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Sample records for beam biomechanical study

  1. Biomechanics or Necromechanics? Or How to Interpret Biomechanical Studies

    PubMed Central

    Brand, Richard A

    2002-01-01

    The field of biomechanics is inextricably linked with orthopaedic surgery: loads and load distribution play a major role in the problems we treat and in the success and failure of many of our treatments. Nonetheless, despite powerful investigational tools, I would argue biomechanics has made a relatively minor impact in clinical practice primarily because most studies fail to account for the major distinction between living and nonliving systems: adaptability. While any study requires a clear question or hypothesis or goal, without accounting for adaptability and tissue tolerance, these studies might well be termed "necromechanical." These studies will always have limited clinical relevance unless they contain several key features: 1.) A choice of a mechanical parameter which is arguably a surrogate for relevant biological behavior; 2.) A set of loading regimens which arguably represent the entire range of loadings experienced in vivo; 3.) An explicit discussion of tissue tolerance to the mechanical perturbations of the study; 4.) When appropriate (i.e., the question relates to longer-term effects), an explicit exploration of tissue adaptation over time. Without meeting these requirements, any biomechanical study is suspect and requires interpretation with great caution. When meeting these requirements, biomechanics can provide powerful tools to explain the function of the body and to predict the success or failure of treatments prior to using them on patients. PMID:12180603

  2. A biomechanical approach for in vivo lung tumor motion prediction during external beam radiation therapy

    NASA Astrophysics Data System (ADS)

    Karami, Elham; Gaede, Stewart; Lee, Ting-Yim; Samani, Abbas

    2015-03-01

    Lung Cancer is the leading cause of cancer death in both men and women. Among various treatment methods currently being used in the clinic, External Beam Radiation Therapy (EBRT) is used widely not only as the primary treatment method, but also in combination with chemotherapy and surgery. However, this method may lack desirable dosimetric accuracy because of respiration induced tumor motion. Recently, biomechanical modeling of the respiratory system has become a popular approach for tumor motion prediction and compensation. This approach requires reasonably accurate data pertaining to thoracic pressure variation, diaphragm position and biomechanical properties of the lung tissue in order to predict the lung tissue deformation and tumor motion. In this paper, we present preliminary results of an in vivo study obtained from a Finite Element Model (FEM) of the lung developed to predict tumor motion during respiration.

  3. Biomechanics of Distance Running: A Longitudinal Study

    ERIC Educational Resources Information Center

    Nelson, Richard C.; Gregor, Robert J.

    1976-01-01

    Training for distance running over a long period produces meaningful changes in the running mechanics of experienced runners, as revealed in this longitudinal study of the biomechanical components of stride length, stride rate, stride time, and support and nonsupport time. (MB)

  4. Verification, validation and sensitivity studies in computational biomechanics.

    PubMed

    Anderson, Andrew E; Ellis, Benjamin J; Weiss, Jeffrey A

    2007-06-01

    Computational techniques and software for the analysis of problems in mechanics have naturally moved from their origins in the traditional engineering disciplines to the study of cell, tissue and organ biomechanics. Increasingly complex models have been developed to describe and predict the mechanical behavior of such biological systems. While the availability of advanced computational tools has led to exciting research advances in the field, the utility of these models is often the subject of criticism due to inadequate model verification and validation (V&V). The objective of this review is to present the concepts of verification, validation and sensitivity studies with regard to the construction, analysis and interpretation of models in computational biomechanics. Specific examples from the field are discussed. It is hoped that this review will serve as a guide to the use of V&V principles in the field of computational biomechanics, thereby improving the peer acceptance of studies that use computational modeling techniques.

  5. Verification, Validation and Sensitivity Studies in Computational Biomechanics

    PubMed Central

    Anderson, Andrew E.; Ellis, Benjamin J.; Weiss, Jeffrey A.

    2012-01-01

    Computational techniques and software for the analysis of problems in mechanics have naturally moved from their origins in the traditional engineering disciplines to the study of cell, tissue and organ biomechanics. Increasingly complex models have been developed to describe and predict the mechanical behavior of such biological systems. While the availability of advanced computational tools has led to exciting research advances in the field, the utility of these models is often the subject of criticism due to inadequate model verification and validation. The objective of this review is to present the concepts of verification, validation and sensitivity studies with regard to the construction, analysis and interpretation of models in computational biomechanics. Specific examples from the field are discussed. It is hoped that this review will serve as a guide to the use of verification and validation principles in the field of computational biomechanics, thereby improving the peer acceptance of studies that use computational modeling techniques. PMID:17558646

  6. Use of electronic speckle pattern interferometry to study the biomechanics of human bone and prostheses

    NASA Astrophysics Data System (ADS)

    Heras-Palov, Carlos; Tyrer, John R.; Petzing, Jon N.; Stoyle, Tom F.; Gregg, P. J.

    1995-02-01

    Electronic speckle pattern interferometry (ESPI) is a laser based technique developed for the study of stresses and strains in complex structures. This method consists of the projection of two laser beams onto the object of study. This produces a visible pattern that is recorded by a video camera. When the structure is stressed in a jig, the pattern changes depending on the in- plane and out-of-plane deformation and movement of the surface observed. This allows us to qualify and quantify strain in the whole area under study, in real time. We describe the method of application of ESPI to the study of the biomechanics of the proximal femur, before and after the implantation of the femoral component of a total hip replacement in cadaveric femora, under physiological loads and tensions, and report our preliminary results. The information obtained with this technique should provide a better understanding of the biomechanics of bone after joint replacement.

  7. Using Clinical Gait Case Studies to Enhance Learning in Biomechanics

    ERIC Educational Resources Information Center

    Chester, Victoria

    2011-01-01

    Clinical case studies facilitate the development of clinical reasoning strategies through knowledge and integration of the basic sciences. Case studies have been shown to be more effective in developing problem-solving abilities than the traditional lecture format. To enhance the learning experiences of students in biomechanics, clinical case…

  8. Poor relation between biomechanical and clinical studies for the proximal femoral locking compression plate.

    PubMed

    Viberg, Bjarke; Rasmussen, Katrine M V; Overgaard, Søren; Rogmark, Cecilia

    2017-03-13

    Background and purpose - The proximal femur locking compression plate (PF-LCP) is a new concept in the treatment of hip fractures. When releasing new implants onto the market, biomechanical studies are conducted to evaluate performance of the implant. We investigated the relation between biomechanical and clinical studies on PF-LCP. Methods - A systematic literature search of relevant biomechanical and clinical studies was conducted in PubMed on December 1, 2015. 7 biomechanical studies and 15 clinical studies were included. Results - Even though the biomechanical studies showed equivalent or higher failure loads for femoral neck fracture, the clinical results were far worse, with a 37% complication rate. There were no biomechanical studies on pertrochanteric fractures. Biomechanical studies on subtrochanteric fractures showed that PF-LCP had a lower failure load than with proximal femoral nail, but higher than with angled blade plate. 4 clinical studies had complication rates less than 8% and 9 studies had complication rates between 15% and 53%. Interpretation - There was no clear relation between biomechanical and clinical studies. Biomechanical studies are generally inherently different from clinical studies, as they examine the best possible theoretical use of the implant without considering the long-term outcome in a clinical setting. Properly designed clinical studies are mandatory when introducing new implants, and they cannot be replaced by biomechanical studies.

  9. Segmentation algorithms for ear image data towards biomechanical studies.

    PubMed

    Ferreira, Ana; Gentil, Fernanda; Tavares, João Manuel R S

    2014-01-01

    In recent years, the segmentation, i.e. the identification, of ear structures in video-otoscopy, computerised tomography (CT) and magnetic resonance (MR) image data, has gained significant importance in the medical imaging area, particularly those in CT and MR imaging. Segmentation is the fundamental step of any automated technique for supporting the medical diagnosis and, in particular, in biomechanics studies, for building realistic geometric models of ear structures. In this paper, a review of the algorithms used in ear segmentation is presented. The review includes an introduction to the usually biomechanical modelling approaches and also to the common imaging modalities. Afterwards, several segmentation algorithms for ear image data are described, and their specificities and difficulties as well as their advantages and disadvantages are identified and analysed using experimental examples. Finally, the conclusions are presented as well as a discussion about possible trends for future research concerning the ear segmentation.

  10. Biomechanical study of tarsometatarsal joint fusion using finite element analysis.

    PubMed

    Wang, Yan; Li, Zengyong; Zhang, Ming

    2014-11-01

    Complications of surgeries in foot and ankle bring patients with severe sufferings. Sufficient understanding of the internal biomechanical information such as stress distribution, contact pressure, and deformation is critical to estimate the effectiveness of surgical treatments and avoid complications. Foot and ankle is an intricate and synergetic system, and localized intervention may alter the functions to the adjacent components. The aim of this study was to estimate biomechanical effects of the TMT joint fusion using comprehensive finite element (FE) analysis. A foot and ankle model consists of 28 bones, 72 ligaments, and plantar fascia with soft tissues embracing all the segments. Kinematic information and ground reaction force during gait were obtained from motion analysis. Three gait instants namely the first peak, second peak and mid-stance were simulated in a normal foot and a foot with TMT joint fusion. It was found that contact pressure on plantar foot increased by 0.42%, 19% and 37%, respectively after TMT fusion compared with normal foot walking. Navico-cuneiform and fifth meta-cuboid joints sustained 27% and 40% increase in contact pressure at second peak, implying potential risk of joint problems such as arthritis. Von Mises stress in the second metatarsal bone increased by 22% at midstance, making it susceptible to stress fracture. This study provides biomechanical information for understanding the possible consequences of TMT joint fusion.

  11. Ion Beam Propulsion Study

    NASA Technical Reports Server (NTRS)

    2008-01-01

    The Ion Beam Propulsion Study was a joint high-level study between the Applied Physics Laboratory operated by NASA and ASRC Aerospace at Kennedy Space Center, Florida, and Berkeley Scientific, Berkeley, California. The results were promising and suggested that work should continue if future funding becomes available. The application of ion thrusters for spacecraft propulsion is limited to quite modest ion sources with similarly modest ion beam parameters because of the mass penalty associated with the ion source and its power supply system. Also, the ion source technology has not been able to provide very high-power ion beams. Small ion beam propulsion systems were used with considerable success. Ion propulsion systems brought into practice use an onboard ion source to form an energetic ion beam, typically Xe+ ions, as the propellant. Such systems were used for steering and correction of telecommunication satellites and as the main thruster for the Deep Space 1 demonstration mission. In recent years, "giant" ion sources were developed for the controlled-fusion research effort worldwide, with beam parameters many orders of magnitude greater than the tiny ones of conventional space thruster application. The advent of such huge ion beam sources and the need for advanced propulsion systems for exploration of the solar system suggest a fresh look at ion beam propulsion, now with the giant fusion sources in mind.

  12. The anisotropic hyperelastic biomechanical response of the vocal ligament and implications for frequency regulation: a case study.

    PubMed

    Kelleher, Jordan E; Siegmund, Thomas; Du, Mindy; Naseri, Elhum; Chan, Roger W

    2013-03-01

    One of the primary mechanisms to vary one's vocal frequency is through vocal fold length changes. As stress and deformation are linked to each other, it is hypothesized that the anisotropy in the biomechanical properties of the vocal fold tissue would affect the phonation characteristics. A biomechanical model of vibrational frequency rise during vocal fold elongation is developed which combines an advanced biomechanical characterization protocol of the vocal fold tissue with continuum beam models. Biomechanical response of the tissue is related to a microstructurally informed, anisotropic, nonlinear hyperelastic constitutive model. A microstructural characteristic (the dispersion of collagen) was represented through a statistical orientation function acquired from a second harmonic generation image of the vocal ligament. Continuum models of vibration were constructed based upon Euler-Bernoulli and Timoshenko beam theories, and applied to the study of the vibration of a vocal ligament specimen. From the natural frequency predictions in dependence of elongation, two competing processes in frequency control emerged, i.e., the applied tension raises the frequency while simultaneously shear deformation lowers the frequency. Shear becomes much more substantial at higher modes of vibration and for highly anisotropic tissues. The analysis was developed as a case study based on a human vocal ligament specimen.

  13. Pilot study of manual sugarcane harvesting using biomechanical analysis.

    PubMed

    Clementson, C L; Hansen, A C

    2008-07-01

    In many countries, sugar cane harvesting is a very labor-intensive activity in which workers usually become fatigued after manually cutting the cane for a few hours. They need frequent pauses for rest, and they experience sustained injuries from excessive stress on the joints and muscles of the body. The cutting tool and motion involved directly influence the stresses created. A cutting tool that has not been designed by taking into consideration occupational biomechanics can lead to unnecessary strains in the body's muscle system, resulting in injuries. The purpose of this research was to carry out a pilot study of the impact of two common manual sugarcane cutting tools and the cutting posture they induce on the body with the aid of biomechanics. The machete and the cutlass from South Africa and Guyana, respectively, were examined to determine the cutting forces. Using static strength prediction modeling, the body stress levels at the point of cut in the cutting motion were determined. The cutting postures of three subjects were contrasted, their extreme postures were identified, and suggestions were made to improve the ergonomics of the cutting activity. The results of this pilot study showed that the cutlass required less cutting force than the machete because of the slicing cut provided by the curved blade edge of the cutlass. However, the biomechanical analysis indicated that the bent blade of the machete required less flexion of the back and therefore was likely to cause less back fatigue and injury. An improved design of the sugarcane manual harvesting tool should incorporate the bend of the machete to reduce flexion and a curved cutting edge that provides a slicing cut.

  14. Absorbable scaphoid screw development: a comparative study on biomechanics

    PubMed Central

    Wang, Yi; Song, Muguo; Xu, Yongqing; He, Xiaoqing; Zhu, YueLiang

    2016-01-01

    Background The scaphoid is critical for maintaining the stability and movement of the wrist joints. This study aimed to develop a new internal fixator absorbable scaphoid screw (ASS) for fixation of the scaphoid waist after fracture and to test the biomechanical characteristics of ASS. Materials and methods An ASS was prepared using polylactic acids and designed based on scaphoid measurements and anatomic features. Twenty fractured scaphoid waist specimens were randomly divided into experimental and control groups (n=10/group). Reduction and internal fixation of the scaphoid were achieved with either Kirschner wires (K-wires) or ASS. A moving target simulator was used to test palmar flexion and dorsal extension, with the range of testing (waist movement) set from 5° of palmar flexion to 25° of dorsal extension. Flexion and extension were repeated 2,000 times for each specimen. Fracture gap displacements were measured with a computerized tomography scanning. Scaphoid tensile and bending strengths were measured by using a hydraulic pressure biomechanical system. Results Prior to biomechanical fatigue testing, fracture gap displacements were 0.16±0.02 mm and 0.22±0.02 mm in the ASS and K-wire groups, respectively. After fatigue testing, fracture gap displacements in the ASS and the K-wire groups were 0.21±0.03 mm and 1.52±0.07 mm, respectively. The tensile strengths for the ASS and K-wire groups were 0.95±0.02 MPa and 0.63±0.02 MPa, respectively. Conclusion Fixation using an ASS provided sufficient mechanical support for the scaphoid after fracture. PMID:27217756

  15. Considerations for Reporting Finite Element Analysis Studies in Biomechanics

    PubMed Central

    Erdemir, Ahmet; Guess, Trent M.; Halloran, Jason; Tadepalli, Srinivas C.; Morrison, Tina M.

    2012-01-01

    Simulation-based medicine and the development of complex computer models of biological structures is becoming ubiquitous for advancing biomedical engineering and clinical research. Finite element analysis (FEA) has been widely used in the last few decades to understand and predict biomechanical phenomena. Modeling and simulation approaches in biomechanics are highly interdisciplinary, involving novice and skilled developers in all areas of biomedical engineering and biology. While recent advances in model development and simulation platforms offer a wide range of tools to investigators, the decision making process during modeling and simulation has become more opaque. Hence, reliability of such models used for medical decision making and for driving multiscale analysis comes into question. Establishing guidelines for model development and dissemination is a daunting task, particularly with the complex and convoluted models used in FEA. Nonetheless, if better reporting can be established, researchers will have a better understanding of a model’s value and the potential for reusability through sharing will be bolstered. Thus, the goal of this document is to identify resources and considerate reporting parameters for FEA studies in biomechanics. These entail various levels of reporting parameters for model identification, model structure, simulation structure, verification, validation, and availability. While we recognize that it may not be possible to provide and detail all of the reporting considerations presented, it is possible to establish a level of confidence with selective use of these parameters. More detailed reporting, however, can establish an explicit outline of the decision-making process in simulation-based analysis for enhanced reproducibility, reusability, and sharing. PMID:22236526

  16. Biomechanical study of a hat type cervical intervertebral fusion cage.

    PubMed

    Gu, Yu-Tong; Jia, Lian-Shun; Chen, Tong-Yi

    2007-02-01

    The purpose of this study was to evaluate the biomechanical effect of a hat type cervical intervertebral fusion cage (HCIFC). In this in vitro biomechanical study, 48 goat cervical spines (C2-5) were tested in flexion, extension, axial rotation, and lateral bending with a nondestructive stiffness method using a nonconstrained testing apparatus, and three-dimensional displacement was measured. Autologous iliac bone and cervical spine intervertebral fusion cage were implanted according to manufacturers' information after complete discectomy (C3-4). Eight spines in each of the following groups were tested: intact, autologous iliac bone graft, Harms cage, SynCage C, carbon cage, and HCIFC. The mean apparent stiffness values were calculated from the corresponding load-displacement curves. Additionally, cage volume and volume-related stiffness were determined. The stiffness of the SynCage C was statistically greatest in all directions. After implantation of the HCIFC, flexion stiffness increased compared with that of the intact motion segment. There was no significant difference in stiffness between the HCIFC and carbon cage. The stiffness of the HCIFC was statistically higher than that of the Harms cage in axial rotation and significantly lower in flexion, extension, and lateral bending. Volume-related stiffness of all cages was higher than that of iliac bone graft. The Harms cage was highest in volume-related stiffness in all directions. The HCIFC can provide enough primary stability for cervical intervertebral fusion.

  17. Biomechanical Study of Two Peripheral Suture Methods on Repaired Tendons

    PubMed Central

    Qiu, Zhenling

    2015-01-01

    Flexor digitorum tendon injuries are challenging conditions to manage to ensure optimal patient outcomes. While several surgical approaches with high success rates have been developed, there remains no gold standard for suture technique for the repair of flexor tendon injuries. In this study, we compared two distinct peripheral suture methods on the strength of repaired tendons. Pig flexor digitorum profundus tendons were used in biomechanical studies and the biomechanical influence on tendon repair of continuous running peripheral suture (CRPS) and continuous locking peripheral suture (CLPS), were compared, using stitch length ranging from 1mm to 5mm. In CRPS, the 1mm stitch length group displayed the highest maximum load and breaking power, which was 1.57 fold higher than the 2mm stitch length group. Pairwise comparison revealed that the 1 and 2mm groups were statistically different from the 3, 4, and 5mm stitch length groups while comparison among the latter groups was not statistically significant. For CLPS, the 1mm group exhibited consistently the highest maximum load strength and breaking power, which was twice the strength displayed by the 2mm group. Pairwise comparisons between groups showed statistical significance. For future repairs of flexor tendon injuries, 1mm stitch length is highly recommended for simple peripheral suture.

  18. Recent microfluidic devices for studying gamete and embryo biomechanics.

    PubMed

    Lai, David; Takayama, Shuichi; Smith, Gary D

    2015-06-25

    The technical challenges of biomechanic research such as single cell analysis at a high monetary cost, labor, and time for just a small number of measurements is a good match to the strengths of microfluidic devices. New scientific discoveries in the fertilization and embryo development process, of which biomechanics is a major subset of interest, is crucial to fuel the continual improvement of clinical practice in assisted reproduction. The following review will highlight some recent microfluidic devices tailored for gamete and embryo biomechanics where biomimicry arises as a major theme of microfluidic device design and function, and the application of fundamental biomechanic principles are used to improve outcomes of cryopreservation.

  19. Study of beam-beam effects in eRHIC

    SciTech Connect

    Hao, Y.; Litvinenko, V.; Ptitsyn, V.

    2010-05-23

    Beam-beam effects in eRHIC have a number of unique features, which distinguish them from both hadron and lepton colliders. Due to beam-beam interaction, both electron and hadron beams would suffer quality degradation or beam loss from without proper treatments. Those features need novel study and dedicate countermeasures. We study the beam dynamics and resulting luminosity of the characteristics, including mismatch, disruption and pinch effects on electron beam, in additional to their consequences on the opposing beam as a wake field and other incoherent effects of hadron beam. We also carry out countermeasures to prevent beam quality degrade and coherent instability.

  20. High-dose electron beam sterilization of soft-tissue grafts maintains significantly improved biomechanical properties compared to standard gamma treatment.

    PubMed

    Hoburg, A; Keshlaf, S; Schmidt, T; Smith, M; Gohs, U; Perka, C; Pruss, A; Scheffler, S

    2015-06-01

    Allografts have gained increasing popularity in anterior cruciate ligament (ACL) reconstruction. However, one of the major concerns regarding allografts is the possibility of disease transmission. Electron beam (Ebeam) and Gamma radiation have been proven to be successful in sterilization of medical products. In soft tissue sterilization high dosages of gamma irradiation have been shown to be detrimental to biomechanical properties of grafts. Therefore, it was the objective of this study to compare the biomechanical properties of human bone-patellar tendon-bone (BPTB) grafts after ebeam with standard gamma irradiation at medium (25 kGy) and high doses (34 kGy). We hypothesized that the biomechanical properties of Ebeam irradiated grafts would be superior to gamma irradiated grafts. Paired 10 mm-wide human BPTB grafts were harvested from 20 donors split into four groups following irradiation with either gamma or Ebeam (each n = 10): (A) Ebeam 25 kGy, (B) Gamma 25 kGy, (C) Ebeam 34 kGy (D) Gamma 34 kGy and ten non-irradiated BPTB grafts were used as controls. All grafts underwent biomechanical testing which included preconditioning (ten cycles, 0-20 N); cyclic loading (200 cycles, 20-200 N) and a load-to-failure (LTF) test. Stiffness of non-irradiated controls (199.6 ± 59.1 N/mm) and Ebeam sterilized grafts did not significantly differ (152.0 ± 37.0 N/mm; 192.8 ± 58.0 N/mm), while Gamma-irradiated grafts had significantly lower stiffness than controls at both irradiation dosages (25 kGy: 126.1 ± 45.4 N/mm; 34 kGy: 170.6 ± 58.2 N/mm) (p < 0.05). Failure loads at 25 kGy were significantly lower in the gamma group (1,009 ± 400 N), while the failure load was significantly lower in both study groups at high dose irradiation with 34 kGy (Ebeam: 1,139 ± 445 N, Gamma: 1,073 ± 617 N) compared to controls (1,741 ± 304 N) (p < 0.05). Creep was significantly larger in the gamma irradiated groups (25 kGy: 0.96 ± 1.34 mm; 34 kGy: 1.06 ± 0.58 mm) than in the Ebeam (25 k

  1. Effect of patellar thickness on knee flexion in total knee arthroplasty: a biomechanical and experimental study.

    PubMed

    Abolghasemian, Mansour; Samiezadeh, Saeid; Sternheim, Amir; Bougherara, Habiba; Barnes, C Lowry; Backstein, David J

    2014-01-01

    A biomechanical computer-based model was developed to simulate the influence of patellar thickness on passive knee flexion after arthroplasty. Using the computer model of a single-radius, PCL-sacrificing knee prosthesis, a range of patella-implant composite thicknesses was simulated. The biomechanical model was then replicated using two cadaveric knees. A patellar-thickness range of 15 mm was applied to each of the knees. Knee flexion was found to decrease exponentially with increased patellar thickness in both the biomechanical and experimental studies. Importantly, this flexion loss followed an exponential pattern with higher patellar thicknesses in both studies. In order to avoid adverse biomechanical and functional consequences, it is recommended to restore patellar thickness to that of the native knee during total knee arthroplasty.

  2. Physiologic strains in the lumbar spinal ligaments. An in vitro biomechanical study 1981 Volvo Award in Biomechanics.

    PubMed

    Panjabi, M M; Goel, V K; Takata, K

    1982-01-01

    For understanding of the mechanical causes of low-back pain, knowledge of the biomechanics of the various spinal elements is essential. In this in vitro biomechanical study, in situ behavior of spinal ligaments of the L3-4 and L4-5 functional spinal units during physiologic activities was studied in a three-stage procedure. First, 72 load-displacement curves were obtained to determine the three-dimensional flexibility characteristics of the spinal units. Second, three-dimensional morphometric measurements were made of all the spinal ligament attachment points. Finally, a mathematical model was constructed to combine the flexibility and morphometric data and compute the ligament length changes and strains as functions of various spinal movements. In flexion movement, the interspinous and supra-spinous ligaments were found to be subjected to the highest strains, followed by the capsular ligaments and the ligamentum flavum. During extension, it is the anterior longitudinal ligament that has the maximum strain. In lateral bending, the contralateral transverse ligaments carried the highest strains, while the interspinous and supraspinous ligaments were relatively unstrained. In rotation, the capsular ligaments were by far the most strained ligaments.

  3. A biomechanical study of periacetabular defects and cement filling.

    PubMed

    Li, Zuoping; Butala, Neha B; Etheridge, Brandon S; Siegel, Herrick J; Lemons, Jack E; Eberhardt, Alan W

    2007-04-01

    Periacetabular bone metastases cause severe pain and functional disability in cancer patients. Percutaneous acetabuloplasty (PCA) is a minimally invasive, image-guided procedure whereby cement is injected into lesion sites. Pain relief and functional restoration have been observed clinically; however, neither the biomechanical consequences of the lesions nor the effectiveness of the PCA technique are well understood. The objective of this study was to investigate how periacetabular lesion size, cortex involvement, and cement modulus affect pelvic bone stresses and strains under single-legged stance loading. Experiments were performed on a male cadaver pelvis under conditions of intact, periacetabular defect, and cement-filling with surface strains recorded at three strain gage locations. The experimental data were then employed to validate three-dimensional finite element models of the same pelvis, developed using computed tomography data. The models demonstrated that increases in cortical stresses were highest along the posterior column of the acetabulum, adjacent to the defect. Cortical stresses were more profoundly affected in the presence of transcortical defects, as compared to those involving only trabecular bone. Cement filling with a modulus of 2.2 GPa was shown to restore cortical stresses to near intact values, while a decrease in cement modulus due to inclusion of BaSO(4) reduced the restorative effect. Peak acetabular contact pressures increased less than 15% for all simulated defect conditions; however, the contact stresses were reduced to levels below intact in the presence of either cement filling. These results suggest that periacetabular defects may increase the vulnerability of the pelvis to fracture depending on size and cortical involvement and that PCA filling may lower the risk of periacetabular fractures.

  4. Beam Propagation Experimental Study.

    DTIC Science & Technology

    1983-04-01

    and locating the camera next to the FX-100 output switch . The camera trigger was derived directly from the light emitted by the FX-100 output switch ...Instability 20 ASSTRPACT eContinue an reverse aide it necessary and Identify by block number) )A program of extensively diagnosed experiments to investigate ...primary objectives of this research were to measure the rate of erosion of the headIof the beam, and to investigate resistive instabilities, such as

  5. LHC beam-beam compensation studies at RHIC

    SciTech Connect

    Fischer,W.; Abreu, N.; Calaga, R.; Robert-Demolaize, G.; Luo, Y.; Montag, C.

    2009-05-04

    Long-range and head-on beam-beam effects are expected to limit the LHC performance with design parameters. To mitigate long-range effects current carrying wires parallel to the beam were proposed. Two such wires are installed in RHIC where they allow studying the effect of strong long-range beam-beam effects, as well as the compensation of a single long-range interaction. The tests provide benchmark data for simulations and analytical treatments. To reduce the head-on beam-beam effect electron lenses were proposed for both the LHC and RHIC. We present the experimental long-range beam-beam program and report on head-on compensations studies at RHIC, which are based on simulations.

  6. Beam Propagation Experimental Study.

    DTIC Science & Technology

    1982-03-01

    30- -40- -50 I 0 100 200 300 Time (ns) Figure 2. FX-100 diode voltage and current. The gas- insulated coax was charged to 4.2 MV in order to produce...limit the usable gradient. The voltage standoff capability will be further limited by electron bombardment of the insulators , which may lead to flashover ...the low-pressure window for stable propagation has been inferred from measurements of the time delay for the beam arrival at a given axial position. 8

  7. Sensitivity studies of crystalline beams

    SciTech Connect

    Wei, J.; Sessler, A.M.

    1996-07-01

    The equations of motion are presented, appropriate to interacting charged particles of diverse charge and mass, subject to the external forces produced by various kinds of magnetic fields and rf electric fields in storage rings. These equations have been employed in the molecular dynamics simulations for sensitivity studies of crystalline beams. The two necessary conditions for the formation and maintenance of crystalline beams are summarized. Effects of lattice shear and AG focusing, magnetic field imperfection, and ion neutralization on crystalline beam heating is presented.

  8. Quantitative methods for reconstructing tissue biomechanical properties in optical coherence elastography: a comparison study

    PubMed Central

    Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Wu, Chen; Liu, Chih-hao; Wang, Shang; Idugboe, Rita; Raghunathan, Raksha; Sudheendran, Narendran; Aglyamov, Salavat R.; Twa, Michael D.; Larin, Kirill V.

    2015-01-01

    We present a systematic analysis of the accuracy of five different methods for extracting the biomechanical properties of soft samples using optical coherence elastography (OCE). OCE is an emerging noninvasive technique, which allows assessing biomechanical properties of tissues with a micrometer spatial resolution. However, in order to accurately extract biomechanical properties from OCE measurements, application of proper mechanical model is required. In this study, we utilize tissue-mimicking phantoms with controlled elastic properties and investigate the feasibilities of four available methods for reconstructing elasticity (Young’s modulus) based on OCE measurements of an air-pulse induced elastic wave. The approaches are based on the shear wave equation (SWE), the surface wave equation (SuWE), Rayleigh-Lamb frequency equation (RLFE), and finite element method (FEM), Elasticity values were compared with uniaxial mechanical testing. The results show that the RLFE and the FEM are more robust in quantitatively assessing elasticity than the other simplified models. This study provides a foundation and reference for reconstructing the biomechanical properties of tissues from OCE data, which is important for the further development of noninvasive elastography methods. PMID:25860076

  9. Overground vs. treadmill walking on biomechanical energy harvesting: An energetics and EMG study.

    PubMed

    Martin, Jean-Paul; Li, Qingguo

    2017-02-01

    A biomechanical energy harvester is a wearable device that generates electricity from human motion. Walking on a treadmill has been used almost exclusively by researchers for studying the energetic effects of biomechanical energy harvesters and wearable robotics. A treadmill provides the advantage of having long duration trials within a stationary motion capture volume. However, no consensus exists on whether the results from treadmill walking accurately represent overground walking. We aim to investigate how a biomechanical energy harvester performs overground compared to on a treadmill by measuring energy expenditure and muscle activity. Participants (n=15) walked both overground and on a treadmill with and without a lower limb-driven biomechanical energy harvester. Energy expenditure was measured using indirect calorimetry and muscle activity was collected with surface electromyograms on seven superficial lower limb muscles. We observed a similar increase in metabolic cost of transport (Δoverground: 0.28±0.24J/kgm, Δtreadmill: 0.30±0.24J/kgm) from normal walking (overground: 2.56±0.33J/kgm, treadmill: 3.39±0.31J/kgm) to harvester walking (overground: 2.83±0.35J/kgm, treadmill: 3.69±0.32J/kgm) in both walking modes (p>0.05). This was accompanied a significant increase in muscle activity of select muscle groups (p<0.05). There was also a significant increase observed during walking on a treadmill compared to overground walking (p<0.05). In conclusion, our results suggest that although the metabolic cost of transport and muscle activation for treadmill walking is higher than that of overground, when studying the effects of a biomechanical energy harvester, treadmill will give similar net increases when compared to a controlled walking condition, such as normal walking, on the same walking surface.

  10. Studies of beam heating of proton beam profile monitor SEM's

    SciTech Connect

    Pavlovich, Zarko; Osiecki, Thomas H.; Kopp, Sacha E.; /Texas U.

    2005-05-01

    The authors present calculations of the expected temperature rise of proton beam profile monitors due to beam heating. The profile monitors are secondary emission monitors (SEM's) to be made of Titanium foils. The heating is studied to understand whether there is any loss of tension or alignment of such devices. Additionally, calculations of thermally-induced dynamic stress are presented. Ti foil is compared to other materials and also to wire SEM's. The calculations were initially performed for the NuMI beam, where the per-pulse intensity is quite high; for completeness the calculations are also performed for other beam energies and intensities.

  11. Stiffness of various pin configurations for pediatric supracondylar humeral fracture: a systematic review on biomechanical studies.

    PubMed

    Chen, Tony Lin-wei; He, Chang-qiang; Zheng, Ting-qu; Gan, Yan-qun; Huang, Ming-xiang; Zheng, Yan-dong; Zhao, Jing-tao

    2015-09-01

    To compare the biomechanical stability of various pin configurations for pediatric supracondylar humeral fractures under varus, internal rotation, and extension conditions. After electronic retrieval, 11 biomechanical studies were included. Stiffness values of pin configurations under different loading conditions were extracted and pooled. There were no statistically significant differences between two cross pins and two divergent lateral pins on the basis of the 'Hamdi method' (P=0.249-0.737). An additional pin did not strengthen two-pin construct (P=0.124-0.367), but better stabilized fractures with medial comminution (P<0.01). Isolated lateral pins are preferable because of a better balance of a lower risk of nerve injury and comparable fixation strength. Limitations such as differences in experimental setup among recruited studies and small sample size may compromise the methodologic power of this study.

  12. [Longitudinal study of a population exposed to risk of biomechanical overload of the upper limb].

    PubMed

    Martmelli, R; Tobia, L; Lupi, A; Monaco, M; Capitano, T; Ponzi, I; Paoletti, A

    2005-01-01

    One of the most important factors of the work-related musculoskeletal disorders of the upper extremities (WMSDs) is the biomechanical overload. The purpose of this study is to evaluate the possibility of the worker fitting to the job, to decrease the upper limb repetitive stress. In order to this aim, we have collected and compared, in different controls at the distance of two years, the clinical-anamnestic and instrumental data of a cohort of workers in a car industry.

  13. Beam Studies with Electron Columns

    SciTech Connect

    Shiltsev, V.; Valishev, A.; Kuznetsov, G.; Kamerdzhiev, V.; Romanov, A.; /Novosibirsk, IYF

    2009-04-01

    We report preliminary results of experimental studies of 'electron columns' in the Tevatron and in a specialized test setup. In the Tevatron, a beam of 150 GeV protons ionizes residual gas and ionization electrons are stored in an electrostatic trap immersed into strong longitudinal magnetic field. Shifts of proton betatron frequencies are observed. In the test setup, we observe effects pointing to accumulation and escape of ionization electrons.

  14. A biomechanical study of bankart lesion fixation - biodegradable ArthroRivet tack vs. suture repair.

    PubMed

    Collins, Kevin J; Mukherjee, Debi P; Ogden, Alan L; Sadasivan, Kalia K; Albright, James A; Pietrzak, William S

    2007-01-01

    Bioabsorbable fixation is commonly used in soft tissue procedures performed in the shoulder. ArthroRivettrade mark tacks (referred to as rivets here), made from a copolymer of 82% poly-L-lactic acid and 18% polyglycolic acid, were developed for the Bankart procedure. Although a previous in vivo study demonstrated favorable comparison of the fixation strength and absorption characteristics of this device with that of polyglyconate bioabsorbable tacks, there have been no published biomechanical studies of this rivet in the shoulder. Fourteen shoulders were harvested from fresh-frozen cadavers of average age 74 years (46-89). Biomechanical testing was performed by measuring the energy, or work, required to anteriorly displace the humeral head 6 mm from the glenoid. Each shoulder was tested intact, vented, and before and after repair of a simulated Bankart lesion at 0, 45, and 90 degrees of abduction with and without maximal external rotation. Overall, the average work required ranged from 54.7 N-mm to 178.27 N-mm. Although the biomechanical performance of the rivet, based on resistance to anterior displacement of the humeral head, was indistinguishable from that of the suture repair, the statistical power of the test was low due to the large variance in the cadaver specimens. The results, in general, correlated well with those of previously published studies, suggesting the suitability of the bioabsorbable rivet for use in Bankart repair.

  15. MRI-based biomechanical imaging: initial study on early plaque progression and vessel remodeling

    PubMed Central

    Zheng, Jie; Abendschein, Dana R.; Okamoto, Ruth J.; Yang, Deshan; McCommis, Kyle S.; Misselwitz, Bernd; Gropler, Robert J.; Tang, Dalin

    2010-01-01

    The goal of the study is to develop a noninvasive magnetic resonance imaging (MRI)-based biomechanical imaging technique to address biomechanical pathways of atherosclerotic progression and regression in vivo using a 3D fluid-structure interaction (FSI) model. Initial in vivo study was carried out in an early plaque model in pigs that underwent balloon-overstretch injury to the left carotid arteries. Consecutive MRI scans were performed while the pigs were maintained on high cholesterol (progression) or normal chow (regression), with an injection of a plaque-targeted contrast agent, Gadofluorine M. At the end of study, the specimens of carotid arterial segments were dissected and underwent dedicated mechanical testing to determine their material properties. 3D FSI computational model was applied to calculate structure stress and strain distribution. The plaque structure resembles early plaque with thickened intima. Lower maximal flow shear stress correlates with the growth of plaque volume during progression, but not during regression. In contrast, maximal principle structure stress/stain (stress-P1 and strain-P1) were shown to correlate strongly with the change in the plaque dimension during regression, but moderately during progression. This MRI-based biomechanical imaging method may allow for noninvasive dynamic assessment of local hemodynamic forces on the development of atherosclerotic plaques in vivo. PMID:19559552

  16. Low Emittance Electron Beam Studies

    SciTech Connect

    Tikhoplav, Rodion

    2006-01-01

    We have studied the properties of a low emittance electron beam produced by laser pulses incident onto an rf gun photocathode. The experiments were carried out at the A0 photoinjector at Fermilab. Such beam studies are necessary for fixing the design of new Linear Colliders as well as for the development of Free Electron Lasers. An overview of the A0 photoinjector is given in Chapter 1. In Chapter 2 we describe the A0 photoinjector laser system. A stable laser system is imperative for reliable photoinjector operation. After the recent upgrade, we have been able to reach a new level of stability in the pulse-to-pulse fluctuations of the pulse amplitude, and of the temporal and transverse profiles. In Chapter 3 we present a study of transverse emittance versus the shape of the photo-cathode drive-laser pulse. For that purpose a special temporal profile laser shaping device called a pulse-stacker was developed. In Chapter 4 we discuss longitudinal beam dynamics studies using a two macro-particle bunch; this technique is helpful in analyzing pulse compression in the magnetic chicane, as well as velocity bunching effects in the rf-gun and the 9-cell accelerating cavity. In Chapter 5 we introduce a proposal for laser acceleration of electrons. We have developed a laser functioning on the TEM*01 mode, a mode with a longitudinal electric field component which is suitable for such a process. Using this technique at energies above 40 MeV, one would be able to observe laser-based acceleration.

  17. Beam Beam Simulation Studies for NLC And SLC2000

    SciTech Connect

    Thompson, K.A.; Chen, P.; Irwin, J.; Zimmermann, F.; /SLAC

    2010-05-27

    We apply and modify the computer codes CAIN(P.Chen, G.Horton-Smith, T.Ohgaki, A.W.Weidemann, K.Yokoya, contributed to Workshop on Gamma-Gamma Colliders, Berkeley, CA, March 28-31, 1994; SLAC-PUB-6583.) and GUINEAPIG(D.Schulte (DESY), unpublished.) to make detailed studies of the beam-beam interaction in the SLAC design for a future linear collider (NLC), as well as to the proposed SLC2000 project. Using realistic beam distributions, we present simulations related to the tuning and optimization of luminosity in SLC2000 and NLC.

  18. Beam instability studies for the SSC

    SciTech Connect

    Chou, W.

    1994-09-01

    Beam instability studies of the Superconducting Super Collider (SSC) during the period 1989--1993 are briefly reviewed in this paper. Various topics are covered: single bunch and multi-bunch, single beam and beam-beam, parasitic heating and active feedback, etc. Although the SSC will not be built, many of the results obtained from these studies remain as useful references to the accelerator community.

  19. Longitudinal study in male swimmers: a hierachical modeling of energetics and biomechanical contributions for performance.

    PubMed

    Costa, Mário J; Bragada, José A; Marinho, Daniel A; Lopes, Vitor P; Silva, António J; Barbosa, Tiago M

    2013-01-01

    The aim of this study was to assess the pooled and individual response of male swimmers over two consecutive years of training and identify the energetic and biomechanical factors that most contributed for the final performance. Nine competitive swimmers (20.0 ± 3.54 years old; 10.1 ± 3.41 years of training experience; 1.79 ± 0.07 m of height; 71.34 ± 8.78 kg of body mass; 22.35 ± 2.02 kg·m(-2) of body mass index; 1.86 ± 0.07 m of arm span; 116.22 ± 4.99 s of personal record in the 200 m long course freestyle event) performed an incremental test in six occasions to obtain the velocity at 4 mmol of blood lactate (V4) and the peak blood lactate concentrations (Lapeak) as energetics, and the stroke frequency (SF), stroke length (SL), stroke index and swim efficiency as biomechanical variables. Performance was determined based on official time's lists of 200 m freestyle event. Slight non-significant improvements in performance were determined throughout the two season period. All energetic and biomechanical factors also presented slight non-significant variations with training. Swimmers demonstrat-ed high inter-individual differences in the annual adaptations. The best performance predictors were the V4, SF and SL. Each unit of change V4, SF and SL represented an enhancement of 0.11 s, 1.21 s and 0.36 s in performance, respectively. The results show that: (i) competitive male swimmers need at least two consecutive seasons to have slight improvements in performance, energetics and biomechanical profiles; (ii) major improvements in competition performance can be accomplished by improving the V4, SF and SL based on the individual background. Key PointsElite swimmers are able to demonstrate slight changes in performance, energetic and biomechanical characteristics at least during two seasons of training;Additional improvements in competition performance can be accomplished by manipulating the V4, SF and SL based on the individual background.Each unit of change V4

  20. Importance of the different posterolateral knee static stabilizers: biomechanical study

    PubMed Central

    Lasmar, Rodrigo Campos Pace; Marques de Almeida, Adriano; Serbino, José Wilson; da Mota Albuquerque, Roberto Freire; Hernandez, Arnaldo José

    2010-01-01

    PURPOSE The purpose of this study was to evaluate the relative importance of the different static stabilizers of the posterolateral corner of the knee in cadavers. METHODS Tests were performed with the application of a varus and external rotation force to the knee in extension at 30 and 60 degrees of flexion using 10 cadaver knees. The forces were applied initially to an intact knee and then repeated after a selective sectioning of the ligaments into the following: section of the lateral collateral ligament; section of the lateral collateral ligament and the popliteofibular complex; and section of the lateral collateral ligament, the popliteofibular complex and the posterolateral capsule. The parameters studied were the angular deformity and stiffness when the knees were submitted to a 15 Newton-meter varus torque and a 6 Newton-meter external tibial torque. Statistical analysis was performed using the ANOVA (Analysis of Variance) and Tukey’s tests. RESULTS AND CONCLUSION Our findings showed that the lateral collateral ligament was important in varus stability at 0, 30 and 60 degrees. The popliteofibular complex was the most important structure for external rotation stability at all angles of flexion and was also important for varus stability at 30 and 60 degrees. The posterolateral capsule was important for varus stability at 0 and 30 degrees and for external rotation stability in extension. Level of evidence: Level IV (cadaver study). PMID:20454502

  1. Biomechanics of Interspinous Devices

    PubMed Central

    Parchi, Paolo D.; Evangelisti, Gisberto; Vertuccio, Antonella; Piolanti, Nicola; Andreani, Lorenzo; Cervi, Valentina; Giannetti, Christian; Calvosa, Giuseppe; Lisanti, Michele

    2014-01-01

    A number of interspinous devices (ISD) have been introduced in the lumbar spine implant market. Unfortunately, the use of these devices often is not associated with real comprehension of their biomechanical role. The aim of this paper is to review the biomechanical studies about interspinous devices available in the literature to allow the reader a better comprehension of the effects of these devices on the treated segment and on the adjacent segments of the spine. For this reason, our analysis will be limited to the interspinous devices that have biomechanical studies published in the literature. PMID:25114923

  2. Collimation Studies with Hollow Electron Beams

    SciTech Connect

    Stancari, G.; Annala, G.; Johnson, T.R.; Saewert, G.W.; Shiltsev, V.; Still, D.A.; Valishev, A.; /Fermilab

    2011-08-01

    Recent experimental studies at the Fermilab Tevatron collider have shown that magnetically confined hollow electron beams can act as a new kind of collimator for high-intensity beams in storage rings. In a hollow electron beam collimator, electrons enclose the circulating beam. Their electric charge kicks halo particles transversely. If their distribution is axially symmetric, the beam core is unaffected. This device is complementary to conventional two-stage collimation systems: the electron beam can be placed arbitrarily close to the circulating beam; and particle removal is smooth, so that the device is a diffusion enhancer rather than a hard aperture limitation. The concept was tested in the Tevatron collider using a hollow electron gun installed in one of the existing electron lenses. We describe some of the technical aspects of hollow-beam scraping and the results of recent measurements.

  3. Biomechanical study of the final push-pull in archery.

    PubMed

    Leroyer, P; Van Hoecke, J; Helal, J N

    1993-02-01

    The purpose of this study was to analyse archery performance among eight archers of different abilities by means of displacement pull-hand measurements during the final push-pull phase of the shoot. The archers showed an irregular displacement negatively related to their technical level. Displacement signal analysis showed high power levels in both the 0-5 Hz and 8-12 Hz ranges. The latter peak corresponds to electromyographic tremor observed during a prolonged push-pull effort. The results are discussed in relation to some potentially helpful training procedures such as biofeedback and strength conditioning.

  4. Tissue-Engineering for the Study of Cardiac Biomechanics

    PubMed Central

    Ma, Stephen P.; Vunjak-Novakovic, Gordana

    2016-01-01

    The notion that both adaptive and maladaptive cardiac remodeling occurs in response to mechanical loading has informed recent progress in cardiac tissue engineering. Today, human cardiac tissues engineered in vitro offer complementary knowledge to that currently provided by animal models, with profound implications to personalized medicine. We review here recent advances in the understanding of the roles of mechanical signals in normal and pathological cardiac function, and their application in clinical translation of tissue engineering strategies to regenerative medicine and in vitro study of disease. PMID:26720588

  5. Biomechanical study of the tibia in knee replacement revision.

    PubMed

    Quílez, M P; Pérez, M A; Seral-García, B

    2015-01-01

    The best management of severe bone defects following total knee replacement is still controversial. Metal augments, tantalum cones and porous tibial sleeves could help the surgeon to manage any type of bone loss, providing a stable and durable knee joint reconstruction. Five different types of prostheses have been analysed: one prosthesis with straight stem; two prostheses with offset stem, with and without supplement, and two prostheses with sleeves, with and without stem. The purpose of this study is to report a finite element study of revision knee tibial implants. The main objective was to analyse the tibial bone density changes and Von Misses tension changes following different tibial implant designs. In all cases, the bone density decreases in the proximal epiphysis and medullary channels, with a bone density increase also being predicted in the diaphysis and at the bone around the stems tips. The highest value of Von Misses stress has been obtained for the straight tibial stem, and the lowest for the stemless metaphyseal sleeves prosthesis.

  6. A biomechanical study of the finger pulley system during repair.

    PubMed

    Amirouche, F; Gonzalez, M; Koldoff, J; Tioco, J; Ham, K

    2002-01-01

    This paper addresses the mechanics of the finger/pulley system when subjected to various excisions and repairs. Several cadaver hands were used to study the finger/pulley's function, finger joint dynamics, and the relationship between tendon excursion and finger joint angles of rotation. By using a method of continuous and simultaneous data acquisition of the entire finger joint's motion, a more detailed analysis was achieved. Our experimental investigation is based on the use of four micro-potentiometers inserted at the finger's joints and a pulley system to simulate tendon excursion. Using this procedure, a detailed kinematic analysis of the entire finger was performed. This included analysis of the intact hand, various pulley excisions, and reconstruction. In addition to introducing a new method of acquisition, a mathematical model was developed for the inverse dynamic analysis of the finger pulley system. From this model, the torques required at the joints for the motion were computed. The results provided new insight into possible ways of characterizing kinematic changes resulting from pulley damage and repair.

  7. Biomechanical study of different plate configurations for distal humerus osteosynthesis.

    PubMed

    Bogataj, M; Kosel, F; Norris, R; Krkovic, M; Brojan, M

    2015-05-01

    Fractures of the distal humerus are most commonly fixed by open reduction and internal fixation, using plates and screws, either in a locking or in a non-locking construct. Three different plating systems are commonly used in practice. The most important differences between them are in plate orientation, which affects both the rigidity of the osteosynthesis and invasiveness of the surgical procedure. Unfortunately, there is no common agreement between surgeons about which plate configuration brings the best clinical outcome. In this study, we investigate the theoretical rigidity of plate osteosyntheses considering two types of AO/ASIF configurations (90° angle between plates), Mayo clinic (Acumed) configuration (180° between plates) and dorsal fixation of both plates. We also compared the results for cases with and without contact between the bone fragments. In the case of no bone contact, the Mayo clinic plate configuration is found to be the most rigid, followed by both AO/ASIF plate configurations, and the least rigid system is the Korosec plate configuration. On the other hand, no significant differences between all types of fixation configurations are found in cases with contact in-between the bone fragments. Our findings show that this contact is very important and can compensate for the lack of load carrying capacity of the implants. This could therefore incite other implant fixation solutions, leading to less invasive surgical procedures and consequently improved clinical outcome.

  8. A biomechanical study of pediatric flexor profundus tendon repair

    PubMed Central

    Al-Thunayan, Turki A.; Al-Zahrani, Mohammed T.; Hakeem, Ahmad A.; Al-Zahrani, Fahad M.; Al-Qattan, Mohammad M.

    2016-01-01

    Objectives: To investigate the tensile strength of repaired flexor profundus tendons in young lambs, which would be equivalent to repairs in children older than 2 years of age. Methods: A comparative in-vitro experimental study conducted at King Saud University, Riyadh, Kingdom of Saudi Arabia from October 2014 to December 2015. We utilized 30 flexor profundus tendons of young lambs with a width of 4 mm. All tendons were repaired with a 4-strand repair technique using 4/0 polypropylene core sutures. In group I (n=10 tendons), 2 separate figure-of-eight sutures were applied. In group II (n=10 tendons), simple locking sutures were added to the corners of 2 separate figure-of-eight sutures. In group III (n=10 tendons), the locked cruciate repair was used. All tendon repairs were tested to single-cycle tensile failure. Results: There was no significant difference between groups II and III with regards to gap and breaking forces; and all forces of these 2 groups were significantly higher than the forces in group I. Conclusion: It was concluded that 4 mm-wide pediatric flexor tendons allow a 4-strand repair and the use of 4/0 sutures. The use of locking sutures increases the tensile strength to values that may allow protective mobilization in children. PMID:27570850

  9. [Biomechanical study of lumbar spine under different vibration conditions].

    PubMed

    Xiang, Pin; Du, Chengfei; Mo, Zhongjun; Gong, He; Wang, Lizhen; Fan, Yubo

    2015-02-01

    We observed the effect of vibration parameters on lumbar spine under different vibration conditions using finite element analysis method in our laboratory. In this study, the CT-images of L1-L5 segments were obtained. All images were used to develop 3D geometrical model using the Mimics10. 01 (Materialise, Belgium). Then it was modified using Geomagic Studio12. 0 (Raindrop Geomagic Inc. USA). Finite element (FE) mesh model was generated by Hypermesh11. 0 (Altair Engineering, Inc. USA) and Abaqus. Abaqus was used to calculate the stress distribution of L1-L5 under different vibration conditions. It was found that in a vibration cycle, tensile stress was occurred on lumbar vertebra mainly. Stress distributed evenly and stress concentration occurred on the left rear side of the upper endplate. The stress had no obvious changes under different frequencies, but the stress was higher when amplitude was greater. In conclusion, frequency and amplitude parameters have little effect on the stress distribution in vertebra. The stress magnitude is positively correlated with the amplitude.

  10. Studying neuronal biomechanics and its role in CNS development

    NASA Astrophysics Data System (ADS)

    Franze, Kristian; Svoboda, Hanno; da F. Costa, Luciano; Guck, Jochen; Holt, Christine

    2013-03-01

    During the development of the nervous system, neurons migrate and grow over great distances. Currently, our understanding of nervous tissue development is, in large part, based on studies of biochemical signaling. Despite the fact that forces are involved in any kind of cell motion, mechanical aspects have so far rarely been considered. Here we used deformable cell culture substrates, traction force microscopy and calcium imaging to investigate how neurons probe and respond to their mechanical environment. While the growth rate of retinal ganglion cell axons was increased on stiffer substrates, their tendency to grow in bundles, which they show in vivo, was significantly enhanced on more compliant substrates. Moreover, if grown on substrates incorporating linear stiffness gradients, neuronal axons were repelled by stiff substrates. Mechanosensing involved the application of forces driven by the interaction of actin and myosin II, and the activation of stretch-activated ion channels leading to calcium influxes into the cells. Applying a modified atomic force microscopy techniquein vivo, we found mechanical gradients in developing brain tissue along which neurons grow. The application of chondroitin sulfate, which is a major extracellular matrix component in the developing brain, changed tissue mechanics and disrupted axonal pathfinding. Hence, our data suggest that neuronal growth is not only guided by chemical signals - as it is currently assumed - but also by the nervous tissue's mechanical properties.

  11. Biomechanical wall properties of the human rectum. A study with impedance planimetry.

    PubMed Central

    Dall, F H; Jørgensen, C S; Houe, D; Gregersen, H; Djurhuus, J C

    1993-01-01

    Biomechanical properties of the rectal wall were studied in 17 healthy adult volunteers (nine men and eight women). With impedance planimetry it is possible to obtain simultaneous measurements of pressure and rectal cross sectional area (CSA) during balloon inflations. Rectal distensions were done with an intraluminal balloon using specified pressures up to 40 cmH2O above baseline rectal pressure. Balloon inflation elicited a phase of rapid increase in rectal CSA followed by a phase of slow increase until a steady state was reached. Steady state occurred within 67 to 140 seconds with the shortest period at the highest distension pressures. Steady state rectal CSA values had a non-linear relation to increasing distension pressure. Rectal CSA values in women showed a tendency of being slightly higher than male values at all pressure steps with a significant difference at 3 and 5 cm H2O. Biomechanical parameters were calculated from rectal CSA pressure relations. Circumferential wall tension increased in a linear way. Rectal compliance decreased in a non-linear way with no further decline between 30 and 40 cmH2O. The pressure elastic modulus increased steeply until a distension pressure of 35 cmH2O with no further increase to 40 cmH2O. This suggests that rectal tone is reduced as the muscle fails to resist further distension at 35 cmH2O and higher pressures. Impedance planimetry offers new possibilities for investigation of anorectal physiology through the study of segmental biomechanical wall properties of the human rectum. PMID:8244148

  12. Beam simulation studies of ECR beam extraction and low energy beam transport for FRIB

    SciTech Connect

    Ren, Haitao Pozdeyev, Eduard; Lund, Steven M.; Machicoane, Guillaume; Wu, Xiaoyu; Morgan, Glenn

    2016-02-15

    To meet the beam power requirements of 400 kW at the fragmentation target for facility for Rare Isotope Beams (FRIB), simultaneous acceleration of two-charge states should be used for heavier ions. These intense multi-charged ion beams will be produced by a 28 GHz electron cyclotron resonance (ECR) ion source at a high voltage of 35 kV. After extraction, the ion beam will be pre-accelerated to 12 keV/u with a 50 kV platform, transported down to an achromatic charge state selection (CSS) system followed by a vertical transport line, and then injected into a radio frequency quadrupole accelerator. The TRACK code developed at ANL is used to perform the simulations of the ECR beam extraction and low energy beam transport for FRIB. In this study, we include the magnetic field of ECR ion source into simulations. Different initial beam conditions as well as different space charge neutralization levels are tested for the ECR beamline. The beam loss in CSS system and the corresponding protective measures are discussed. The detailed results about the beam dynamic simulation and beam loss in CSS system will be presented in this paper.

  13. Beam simulation studies of ECR beam extraction and low energy beam transport for FRIB

    NASA Astrophysics Data System (ADS)

    Ren, Haitao; Pozdeyev, Eduard; Lund, Steven M.; Machicoane, Guillaume; Wu, Xiaoyu; Morgan, Glenn

    2016-02-01

    To meet the beam power requirements of 400 kW at the fragmentation target for facility for Rare Isotope Beams (FRIB), simultaneous acceleration of two-charge states should be used for heavier ions. These intense multi-charged ion beams will be produced by a 28 GHz electron cyclotron resonance (ECR) ion source at a high voltage of 35 kV. After extraction, the ion beam will be pre-accelerated to 12 keV/u with a 50 kV platform, transported down to an achromatic charge state selection (CSS) system followed by a vertical transport line, and then injected into a radio frequency quadrupole accelerator. The TRACK code developed at ANL is used to perform the simulations of the ECR beam extraction and low energy beam transport for FRIB. In this study, we include the magnetic field of ECR ion source into simulations. Different initial beam conditions as well as different space charge neutralization levels are tested for the ECR beamline. The beam loss in CSS system and the corresponding protective measures are discussed. The detailed results about the beam dynamic simulation and beam loss in CSS system will be presented in this paper.

  14. Microrobotized blasting improves the bone-to-textured implant response. A preclinical in vivo biomechanical study.

    PubMed

    Coelho, Paulo G; Gil, Luiz F; Neiva, Rodrigo; Jimbo, Ryo; Tovar, Nick; Lilin, Thomas; Bonfante, Estevam A

    2016-03-01

    This study evaluated the effect of microrobotized blasting of titanium endosteal implants relative to their manually blasted counterparts. Two different implant systems were utilized presenting two different implant surfaces. Control surfaces (Manual) were fabricated by manually grit blasting the implant surfaces while experimental surfaces (Microblasted) were fabricated through a microrobotized system that provided a one pass grit blasting routine. Both surfaces were created with the same ~50µm average particle size alumina powder at ~310KPa. Surfaces were then etched with 37% HCl for 20min, washed, and packaged through standard industry procedures. The surfaces were characterized through scanning electron microscopy (SEM) and optical interferometry, and were then placed in a beagle dog radius model remaining in vivo for 3 and 6 weeks. The implant removal torque was recorded and statistical analysis evaluated implant system and surface type torque levels as a function of time in vivo. Histologic sections were qualitatively evaluated for tissue response. Electron microscopy depicted textured surfaces for both manual and microblasted surfaces. Optical interferometry showed significantly higher Sa, Sq, values for the microblasted surface and no significant difference for Sds and Sdr values between surfaces. In vivo results depicted that statistically significant gains in biomechanical fixation were obtained for both implant systems tested at 6 weeks in vivo, while only one system presented significant biomechanical gain at 3 weeks. Histologic sections showed qualitative higher amounts of new bone forming around microblasted implants relative to the manually blasted group. Microrobotized blasting resulted in higher biomechanical fixation of endosteal dental implants and should be considered as an alternative for impant surface manufacturing.

  15. Managing Vancouver B1 fractures by cerclage system compared to locking plate fixation - a biomechanical study.

    PubMed

    Gordon, Katharina; Winkler, Martin; Hofstädter, Thomas; Dorn, Ulrich; Augat, Peter

    2016-06-01

    With increasing life expectancy and number of total hip arthroplasties (THA), the need for revision surgery is increasing too. The aim of this study was to evaluate the optimal fracture treatment for a clinically characteristic Vancouver B1 fracture. We hypothesized that locking plate fixation has biomechanical advantages over fixation with a simple cerclage system. Additionally, we hypothesized that removal of the primary short stem and revision with a long stem would show biomechanical benefit. The biomechanical testing was performed with a static and a dynamic loading protocol on twenty 4th Generation sawbones. These were divided into four different groups (n = 5 each). In group 1, the primary uncemented short stem remained and the fracture was stabilized with a locking plate. In group 2, the primary stem remained and the fracture was stabilized with a cerclage stabilization system containing two stabilizers and four cerclages. In group 3, the primary stem was replaced by an uncemented long revision stem and the fracture was fixed with a locking plate. In group 4, the short stem was replaced by a long revision stem and the fracture was fixed with the cerclage system. Static testing revealed that the revision of the short stem with the long stem caused a 2-fold (p < 0.001, ANOVA) increase of axial stiffness. In dynamic testing, the number of cycles to failure was 4 times (p < 0.001, ANOVA) higher with the long revision stem. Compared to locked plating cerclage wiring demonstrated a 26% more cycles to failure (p = 0.031, ANOVA). The load to failure was 91% larger (p < 0.001, ANOVA) with the long revision stem and 11% smaller with locked plating (p < 0.001, ANOVA). In conclusion, the present biomechanical study indicates that periprosthetic Vancouver B1 fractures can be sufficiently fixed by simple cerclage systems. Revision with a long replacement stem provides a superior mechanical stability regardless of type of osteosynthesis fixation and is therefore a viable

  16. [Biomechanics study during march with different military equipment of equal carrying load].

    PubMed

    Lang, Y Y

    1992-03-01

    The purpose of the study is to select the best military equipment of equal carrying load by the index of biomechanics. Six healthy young men whose age varied between 19 and 25 years were volunteered, in the experiment. They were required to march 1.5 h, carried with different military equipment of equal weight, 25 kg, at a speed of 5 km/h. The centre of gravity of the body and its kinesic parameters were measured before and after the march. The frequency and length of pace were measured during the march. The results of the study indicated that the displacement of the body's centre of gravity carrying equipment I was the most evident, whereas the least displacement of centre of gravity of the body was that carrying equipment II. The frequency of pace during the march was reduced in all three carrying different kinds of equipment, the most evident being that carrying equipment I; the length of pace became bigger with those carrying equipment II and III; the speed of pace was decelerated using equipment I, but it was quickened with equipment II. The change of kinesic parameters have no significant difference among the three. In summary; equipment II conforms best to biomechanical principles, whereas equipment I is the worst.

  17. Physical-Performance Outcomes and Biomechanical Correlates from the 32-Week Yoga Empowers Seniors Study

    PubMed Central

    Wang, Man-Ying; Yu, Sean S.-Y.

    2016-01-01

    Background. Yoga Empowers Seniors Study (YESS) quantified physical demands associated with yoga performance using biomechanical methods. This study evaluated the efficacy of the program on physical function outcomes. Methods. Twenty community-dwelling older adults aged 70.7 ± 3.8 years attended biweekly 60-minute Hatha yoga classes for 32 weeks. Four domains of the physical measurements including (1) functional performance, (2) flexibility, (3) muscle strength, and (4) balance were taken at the baseline, 16-week and 32-week time points. Repeated-measures ANOVA omnibus tests and Tukey's post hoc tests were employed to examine the differences in each outcome variable across the 3 time points. Results. Improved timed chair stands (p < 0.01), 8-foot up and go (p < 0.05), 2-min step test (p < 0.05), and vertical reach (p = 0.05) performance were evident. Isometric knee flexor strength (p < 0.05) and repetitions of the heel rise test (p < 0.001) also increased following the 32-week intervention. Both flexibility and balance performance remained unchanged. Conclusions. Significant improvements in physical function and muscle-specific lower-extremity strength occur with the regular practice of a modified Hatha yoga program designed for seniors. These adaptations corresponded with the previously reported biomechanical demands of the poses. PMID:27885329

  18. Low-cost microcontroller platform for studying lymphatic biomechanics in vitro

    PubMed Central

    Kornuta, Jeffrey A.; Nipper, Matthew E.; Dixon, J. Brandon

    2012-01-01

    The pumping innate to collecting lymphatic vessels routinely exposes the endothelium to oscillatory wall shear stress and other dynamic forces. However, studying the mechanical sensitivity of the lymphatic endothelium remains a difficult task due to limitations of commercial or custom systems to apply a variety of time-varying stresses in vitro. Current biomechanical in vitro testing devices are very expensive, limited in capability, or highly complex; rendering them largely inaccessible to the endothelial cell biology community. To address these short-comings, the authors propose a reliable, low-cost platform for augmenting the capabilities of commercially available pumps to produce a wide variety of flow rate waveforms. In particular, the Arduino Uno, a microcontroller development board, is used to provide open-loop control of a digital peristaltic pump using precisely-timed serial commands. In addition, the flexibility of this platform is further demonstrated through its support of a custom-built cell-straining device capable of producing oscillatory strains with varying amplitudes and frequencies. Hence, this microcontroller development board is shown to be an inexpensive, precise, and easy-to-use tool for supplementing in vitro assays to quantify the effects of biomechanical forces on lymphatic endothelial cells. PMID:23178036

  19. Low-cost microcontroller platform for studying lymphatic biomechanics in vitro.

    PubMed

    Kornuta, Jeffrey A; Nipper, Matthew E; Dixon, J Brandon

    2013-01-04

    The pumping innate to collecting lymphatic vessels routinely exposes the endothelium to oscillatory wall shear stress and other dynamic forces. However, studying the mechanical sensitivity of the lymphatic endothelium remains a difficult task due to limitations of commercial or custom systems to apply a variety of time-varying stresses in vitro. Current biomechanical in vitro testing devices are very expensive, limited in capability, or highly complex; rendering them largely inaccessible to the endothelial cell biology community. To address these shortcomings, the authors propose a reliable, low-cost platform for augmenting the capabilities of commercially available pumps to produce a wide variety of flow rate waveforms. In particular, the Arduino Uno, a microcontroller development board, is used to provide open-loop control of a digital peristaltic pump using precisely timed serial commands. In addition, the flexibility of this platform is further demonstrated through its support of a custom-built cell-straining device capable of producing oscillatory strains with varying amplitudes and frequencies. Hence, this microcontroller development board is shown to be an inexpensive, precise, and easy-to-use tool for supplementing in vitro assays to quantify the effects of biomechanical forces on lymphatic endothelial cells.

  20. Biomechanics of oral mucosa

    PubMed Central

    Chen, Junning; Ahmad, Rohana; Li, Wei; Swain, Michael; Li, Qing

    2015-01-01

    The prevalence of prosthodontic treatment has been well recognized, and the need is continuously increasing with the ageing population. While the oral mucosa plays a critical role in the treatment outcome, the associated biomechanics is not yet fully understood. Using the literature available, this paper provides a critical review on four aspects of mucosal biomechanics, including static, dynamic, volumetric and interactive responses, which are interpreted by its elasticity, viscosity/permeability, apparent Poisson's ratio and friction coefficient, respectively. Both empirical studies and numerical models are analysed and compared to gain anatomical and physiological insights. Furthermore, the clinical applications of such biomechanical knowledge on the mucosa are explored to address some critical concerns, including stimuli for tissue remodelling (interstitial hydrostatic pressure), pressure–pain thresholds, tissue displaceability and residual bone resorption. Through this review, the state of the art in mucosal biomechanics and their clinical implications are discussed for future research interests, including clinical applications, computational modelling, design optimization and prosthetic fabrication. PMID:26224566

  1. Bicondylar tibial plateau fractures managed with the Sheffield Hybrid Fixator. Biomechanical study and operative technique.

    PubMed

    Ali, A M; Yang, L; Hashmi, M; Saleh, M

    2001-12-01

    The two main challenges in the management of bicondylar tibial plateau fractures are: Firstly, the compromised skin and soft tissue envelope which invite a high rate of complications following attempted open reduction and dual plating. Secondly, poor bone quality and comminuted fracture patterns, which create difficulty in achieving stable fixation. Although dual plating is considered to be the best mechanical method of stabilizing these complex fractures, there remains concern regarding the high rate of complications associated with extensive soft tissue dissection, required for the insertion of these plates in an already compromised knee. The Sheffield Hybrid fixator (SHF) technique offers a solution to the two main problems of these difficult fractures by minimizing soft tissue dissection, since bone fragments are reduced and fixed percutaneously, and providing superior cancellous bone purchase with beam loading stabilization for comminuted fractures. Our biomechanical testing showed the SHF with four tensioned wires to be as strong as dual plating and able to provide adequate mechanical stability in the fixation of bicondylar tibial plateau fractures. This was confirmed clinically by a prospective review of the use of the SHF at our centre, for managing complex and high-energy tibial plateau fractures with a good final outcome and no cases of deep infection or septic arthritis.

  2. The use of wearable inertial motion sensors in human lower limb biomechanics studies: a systematic review.

    PubMed

    Fong, Daniel Tik-Pui; Chan, Yue-Yan

    2010-01-01

    Wearable motion sensors consisting of accelerometers, gyroscopes and magnetic sensors are readily available nowadays. The small size and low production costs of motion sensors make them a very good tool for human motions analysis. However, data processing and accuracy of the collected data are important issues for research purposes. In this paper, we aim to review the literature related to usage of inertial sensors in human lower limb biomechanics studies. A systematic search was done in the following search engines: ISI Web of Knowledge, Medline, SportDiscus and IEEE Xplore. Thirty nine full papers and conference abstracts with related topics were included in this review. The type of sensor involved, data collection methods, study design, validation methods and its applications were reviewed.

  3. Ulnar impaction syndrome with different operative methods: a comparative biomechanical study

    PubMed Central

    Yu, Ya-Dong; Wu, Tao; Tian, Fang-Tao; Shang, Yun-Tao; Yu, Xiao-Fei; Bai, Yan-Bin; Han, Chang-Ling

    2015-01-01

    Objective: Ulnar impaction syndrome seriously impairs wrist and hand function. Three main treatment procedures are available; however, little systematic research on the post-operation changes in wrist biomechanics currently exists. This study aimed to determine the long-term effects of these procedures and the optimal treatment methods for ulnar impaction syndrome. Methods: Twenty-four cases of fresh upper limb specimens were randomized into four groups: (1) the control group, (2) the ulnar-shortening operation group, (3) the Sauvé-Kapandji procedure group (distal radioulnar arthrodesis and intentional distal ulnar pseudoarthrosis), and (4) the Darrach procedure group (distal ulna resection). After keeping the wrist in a neutral position, a pressure sensitive film was applied. Starting at 0 N, the load was increased gradually at a speed of 0.1 N/s until reaching 200 N and then maintained for 60 s by the CSS-44020 series biomechanical machine. Then, the pressure sensitive films from each group were measured, and the results were analyzed with SPSS software. Results: The mean pressure and force on the ulna in the groups followed a decreasing trend from the control group, Sauvé-Kapandji procedure group and ulnar-shortening operation group. The mean pressure of the scaphoid fossa and the force on distal aspect of the radius in the groups followed an increasing trend from the control group, Sauvé-Kapandji procedure group, ulnar-shortening operation group and Darrach procedure group. This study found no significant differences in the mean pressure of the scaphoid fossa and the force on distal aspect of the radius between the Sauvé-Kapandji procedure group and the ulnar-shortening operation group. The Sauvé-Kapandji procedure group showed the greatest mean pressure on lunate fossa. Conclusions: In this comprehensive analysis of wrist biomechanics, the ulnar-shortening operation was superior to the Sauvé-Kapandji procedure and Darrach procedure, which adequately

  4. Experimental observation, theoretical models, and biomechanical inference in the study of mandibular form.

    PubMed

    Daegling, D J; Hylander, W L

    2000-08-01

    Experimental studies and mathematical models are disparate approaches for inferring the stress and strain environment in mammalian jaws. Experimental designs offer accurate, although limited, characterization of biomechanical behavior, while mathematical approaches (finite element modeling in particular) offer unparalleled precision in depiction of strain magnitudes, directions, and gradients throughout the mandible. Because the empirical (experimental) and theoretical (mathematical) perspectives differ in their initial assumptions and their proximate goals, the two methods can yield divergent conclusions about how masticatory stresses are distributed in the dentary. These different sources of inference may, therefore, tangibly influence subsequent biological interpretation. In vitro observation of bone strain in primate mandibles under controlled loading conditions offers a test of finite element model predictions. Two issues which have been addressed by both finite element models and experimental approaches are: (1) the distribution of torsional shear strains in anthropoid jaws and (2) the dissipation of bite forces in the human alveolar process. Not surprisingly, the experimental data and mathematical models agree on some issues, but on others exhibit discordance. Achieving congruence between these methods is critical if the nature of the relationship of masticatory stress to mandibular form is to be intelligently assessed. A case study of functional/mechanical significance of gnathic morphology in the hominid genus Paranthropus offers insight into the potential benefit of combining theoretical and experimental approaches. Certain finite element analyses claim to have identified a biomechanical problem unrecognized in previous comparative work, which, in essence, is that the enlarged transverse dimensions of the postcanine corpus may have a less important role in resisting torsional stresses than previously thought. Experimental data have identified

  5. Biomechanical effect of isolated capitate shortening in Kienbock's disease: an anatomical study.

    PubMed

    Werber, K-D; Schmelz, R; Peimer, C A; Wagenpfeil, S; Machens, H-G; Lohmeyer, J A

    2013-06-01

    Multiple operations have been proposed to slow the progression of osteonecrosis and secondary carpal damage in Kienböck's disease. To assess the biomechanical changes after capitate shorting, we inserted pressure-testing devices into the carpal and radiocarpal joints in an anatomical study. Pressure sensors were placed into eight thawed non-fixated human cadaver arms to measure the forces transmitted in physiological loading. Longitudinal 9.8 N and 19.6 N forces were applied before and after capitate shortening. After capitate shortening, significant load reduction on the lunate was evident in all specimens. An average decrease of 49% was seen under a 9.8 N load and 56% under a 19.6 N load. The load was transferred to the radial and ulnar intercarpal joints. More relief of pressure on the lunate after isolated capitate shortening is achieved with a shallow angle between the scaphoid and capitate in the posteroanterior radiograph.

  6. Study on Brain Injury Biomechanics Based on the Real Pedestrian Traffic Accidents

    NASA Astrophysics Data System (ADS)

    Feng, Chengjian; Yin, Zhiyong

    This paper aimed to research the dynamic response and injury mechanisms of head based on real pedestrian traffic accidents with video. The kinematics of head contact with the vehicle was reconstructed by using multi-body dynamics models. These calculated parameters such as head impact velocity and impact location and head orientation were applied to the THUMS-4 FE head model as initial conditions. The intracranial pressure and stress of brain were calculated from simulations of head contact with the vehicle. These results were consistent with that of others. It was proved that real traffic accidents combined with simulation analysis can be used to study head injury biomechanics. Increasing in the number of cases, a tolerance limit of brain injury will be put forward.

  7. Fixed-angle screws vs standard screws in acetabular prosthesis fixation: a cadaveric biomechanical study.

    PubMed

    Hugate, Ronald R; Dickey, Ian D; Chen, Qingshan; Wood, Christina M; Sim, Franklin H; Rock, Michael G

    2009-08-01

    Secure fixation of acetabular components in total hip arthroplasty can be challenging. The purpose of this study was to perform biomechanical analysis of cup fixation strength using fixed-angle vs standard screw fixation. Multihole, porous-backed acetabular prostheses were implanted in both acetabuli of 8 cadaveric pelves using standard press-fit techniques. Fixed-angle screws were used on the left side, and standard cancellous screws were used in the right. The use of fixed-angle screws enhanced acetabular fixation substantially under subfailure cyclic loading conditions and load-to-failure. The triradiate screw configuration increases the bending moment required to fail the specimens as well. Fixed-angle screws may be useful for achieving rigid fixation of acetabular prostheses in challenging clinical scenarios.

  8. Robots in human biomechanics--a study on ankle push-off in walking.

    PubMed

    Renjewski, Daniel; Seyfarth, André

    2012-09-01

    In biomechanics, explanatory template models are used to identify the basic mechanisms of human locomotion. However, model predictions often lack verification in a realistic environment. We present a method that uses template model mechanics as a blueprint for a bipedal robot and a corresponding computer simulation. The hypotheses derived from template model studies concerning the function of heel-off in walking are analysed and discrepancies between the template model and its real-world anchor are pointed out. Neither extending the ground clearance of the swinging leg nor an impact reduction at touch-down as an effect of heel lifting was supported by the experiments. To confirm the relevance of the experimental findings, a comparison of robot data to human walking data is discussed and we speculate on an alternative explanation of heel-off in human walking, i.e. that the push-off powers the following leg swing.

  9. Biomechanical Assessment of Stabilization of Simulated Type II Odontoid Fracture with Case Study

    PubMed Central

    Daniel, Roy T.; Klocke, Noelle; Yandamuri, Soumya S.; Bobinski, Lukas; Duff, John M.; Bucklen, Brandon S.

    2017-01-01

    Study Design Researchers created a proper type II dens fracture (DF) and quantified a novel current posterior fixation technique with spacers at C1–C2. A clinical case study supplements this biomechanical analysis. Purpose Researchers explored their hypothesis that spacers combined with posterior instrumentation (PI) reduce range of motion significantly, possibly leading to better fusion outcomes. Overview of Literature Literature shows that the atlantoaxial joint is unique in allowing segmental rotary motion, enabling head turning. With no intervertebral discs at these joints, multiple ligaments bind the axis to the skull base and to the atlas; an intact odontoid (dens) enhances stability. The most common traumatic injury at these strong ligaments is a type II odontoid fracture. Methods Each of seven specimens (C0–C3) was tested on a custom-built six-degrees-of-freedom spine simulator with constructs of intact state, type II DF, C1–C2 PI, PI with joint capsulotomy (PIJC), PI with spacers (PIS) at C1–C2, and spacers alone (SA). A bending moment of 2.0 Nm (1.5°/sec) was applied in flexion-extension (FE), lateral bending (LB), and axial rotation (AR). One-way analysis of variance with repeated measures was performed. Results DF increased motion to 320%, 429%, and 120% versus intact (FE, LB, and AR, respectively). PI significantly reduced motion to 41%, 21%, and 8%. PIJC showed negligible changes from PI. PIS reduced motion to 16%, 14%, and 3%. SA decreased motion to 64%, 24%, and 54%. Reduced motion facilitated solid fusion in an 89-year-old female patient within 1 year. Conclusions Type II odontoid fractures can lead to acute or chronic instability. Current fixation techniques use C1–C2 PI or an anterior dens screw. Addition of spacers alongside PI led to increased biomechanical rigidity over intact motion and may offer an alternative to established surgical fixation techniques. PMID:28243364

  10. Controlled Study of Correlation of Biomechanical Profile of Hemiparetic Patients with Distance Travelled in Six Minutes

    PubMed Central

    Moura, Laís Moreira; Quintão, Mônica Maria Pena; de Carvalho, Karen Santos R.; Carrapatoso, Beatriz Cantanhede; Malfacini, Sabrina Lindenberg L.; da Silva, André Custódio; Orsini, Marco; Nascimento, Osvaldo J.M.; Chermont, Sergio S.M.C.

    2015-01-01

    The six-minute walking test (6MWT) is used to assess exercise tolerance that is associated with motor function of the lower limbs in hemiparetic patients. It is suggested that, for post-stroke subjects, performance in the 6MWT may be limited by biomechanical and cardiovascular factors. Our aim is to determine the correlation between the six-minute walk distance (6MWD) and the biomechanical profile of hemiparetic patients. During this cross-sectional controlled study, 10 hemiparetic patients with heart failure underwent 6MWT (ATS protocol). Tonus (Ashworth Scale) and goniometry of the lower limbs were measured. The average of 6MWD in two tests was 279±8 m. There was a negative correlation between the degree of spasticity for both the sural triceps (r=–0.57, P<0.05), quadriceps (r=–0.58, P<0.05) and the limitation in ankle dorsiflexion and the 6MWD (r=–0.76, P<0.05). Also, there was correlation between hip extension and ankle dorsiflexion limitations with 6MWD (r=0.66, P<0.05), (r=0.77, P<0.05). The negative correlation between the highest spasticity in paretic limb and the 6MWD and the correlation between the lower movement range of paretic hip and ankle suggest association with these factors and gait velocity in 6MWT. Loss percentage represents the percentage calculation between distance traveled and the distance predicted achieved by patients. In this study, the negative correlation between the percentage of loss of 6MWD and the limitation in the ankle dorsiflexion movement suggests that for a minor motion arch of the ankle, there is a higher percentage of walking distance loss foretold. PMID:26487924

  11. Controlled Study of Correlation of Biomechanical Profile of Hemiparetic Patients with Distance Travelled in Six Minutes.

    PubMed

    Moura, Laís Moreira; Quintão, Mônica Maria Pena; de Carvalho, Karen Santos R; Carrapatoso, Beatriz Cantanhede; Malfacini, Sabrina Lindenberg L; da Silva, André Custódio; Orsini, Marco; Nascimento, Osvaldo J M; Chermont, Sergio S M C

    2015-09-24

    The six-minute walking test (6MWT) is used to assess exercise tolerance that is associated with motor function of the lower limbs in hemiparetic patients. It is suggested that, for post-stroke subjects, performance in the 6MWT may be limited by biomechanical and cardiovascular factors. Our aim is to determine the correlation between the six-minute walk distance (6MWD) and the biomechanical profile of hemiparetic patients. During this cross-sectional controlled study, 10 hemiparetic patients with heart failure underwent 6MWT (ATS protocol). Tonus (Ashworth Scale) and goniometry of the lower limbs were measured. The average of 6MWD in two tests was 279±8 m. There was a negative correlation between the degree of spasticity for both the sural triceps (r=-0.57, P<0.05), quadriceps (r=-0.58, P<0.05) and the limitation in ankle dorsiflexion and the 6MWD (r=-0.76, P<0.05). Also, there was correlation between hip extension and ankle dorsiflexion limitations with 6MWD (r=0.66, P<0.05), (r=0.77, P<0.05). The negative correlation between the highest spasticity in paretic limb and the 6MWD and the correlation between the lower movement range of paretic hip and ankle suggest association with these factors and gait velocity in 6MWT. Loss percentage represents the percentage calculation between distance traveled and the distance predicted achieved by patients. In this study, the negative correlation between the percentage of loss of 6MWD and the limitation in the ankle dorsiflexion movement suggests that for a minor motion arch of the ankle, there is a higher percentage of walking distance loss foretold.

  12. Acousto-Optic Beam Steering Study

    DTIC Science & Technology

    1994-08-01

    8217111 INK $ 1 1 illl iII Ill i, R L-TR-94-121 !1!1Il t 11I1!I!11! ilI, / Final Technical Report August 1994 ACOUSTO - OPTIC BEAM STEERING STUDY Harris...contractual obligations or notices on a specific document require that it be returned. For i ..........I ,, ACOUSTO - OPTIC BEAM STEERING STUDY H. W...4. TITLE AND SUBTITLE 5. FUNDING NUMBERS ACOUSTO - OPTIC BEAM STEERING STUDY C - F30602-91-C-0131 PE - 63215C 6. AUTHOR(S) PR - 1405 TA - 02 H. W

  13. Effect of pathological myopia on biomechanical properties: a study by ocular response analyzer

    PubMed Central

    Öner, Veysi; Taş, Mehmet; Özkaya, Erdal; Oruç, Yavuz

    2015-01-01

    AIM To evaluate the ocular response analyzer (ORA) measurements of patients with pathological myopia in comparison with those of emmetropic control subjects, and to investigate the correlation between these ORA measurements and spherical equivalent (SE). METHODS Measurements of 53 eyes of 53 subjects with pathological myopia (SE>-6.00 D) were compared with those of 60 eyes of 60 emmetropic controls. Corneal hysteresis (CH), corneal resistance factor (CRF), noncontact tonometer intraocular pressure (IOPg), and corneal-compensated IOP (IOPcc) were obtained for each subject. The refractive error value was determined as SE via a cycloplegic refraction test. RESULTS The mean age was 54.1±18.9y (ranging from 5 to 88) in the pathological myopic group and 56.2±19.0y (ranging from 6 to 89) in the control group. There were no significant differences between the groups concerning age and sex. CH and CRF were significantly lower in the pathological myopic group than in the control group (P<0.001, P=0.005, respectively). IOPcc and IOPg were significantly higher in the pathological myopic group than in the control group (P<0.001, P=0.009, respectively). There were significantly positive correlations between CH and SE (r=0.565, P<0.001) and between CRF and SE (r=0.364, P=0.007). There were significantly negative correlations between IOPcc and SE (r=-0.432, P=0.001) and between IOPg and SE (r=-0.401, P=0.003). CONCLUSION The present study displayed that pathological myopia affected biomechanical properties measured by ORA. The results of corneal biomechanical properties measured by ORA may need to be appreciated by taking refraction into account. Further, pathological myopia might be related with the increased IOP. PMID:25938057

  14. Silicon nitride films for the protective functional coating: blood compatibility and biomechanical property study.

    PubMed

    Shi, Zhifeng; Wang, Yingjun; Du, Chang; Huang, Nan; Wang, Lin; Ning, Chengyun

    2012-12-01

    Behaviors of silicon nitride films and their relation to blood compatibility and biomechanical have been interesting subjects to researchers. A systematic blood compatibility and biomechanical property investigation on the deposition of silicon-nitride films under varying N₂ and CF₄ flows was carried out by direct current unbalanced magnetron sputtering techniques. Significant role of surface property, chemical bonding state of silicon nitride film and blood compatibility, mechanical properties for the films were observed. The chemical bonding configurations, surface topography, contact angle and mechanical properties were characterized by means of X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and nano-indentation technique and CSEM pin-on-disk tribometer. Blood compatibility of the films was evaluated by platelet adhesion investigation. The results of the platelet adhesion tests shown that the effect of fluorine and nitrogen-doped revealed an intimate relationship between the ratio of polar component and dispersion component of the surface energy and its hemocompatibility. Si-N-O coating can be a great candidate for developing antithrombogenic surfaces in blood contacting materials. The chemical bonding state made an adjustment in microstructured surfaces, once in the totally wettable configuration, may improve the initial contact between platelet and biomedical materials, due to the appropriate ratio of dispersion component and polar component. To resist wear, biomedical components require coatings that are tough and hard, have low friction, and are bio-inert. The study suggests that by Si-N coating the metal surfaces could be a choice to prolong the life of the sliding pair Co-Cr-Mo alloy/UHMWPE implants.

  15. Quantum dots as mineral- and matrix-specific strain gages for bone biomechanical studies

    NASA Astrophysics Data System (ADS)

    Zhu, Peizhi; Xu, Jiadi; Morris, Michael; Ramamoorthy, Ayyalusamy; Sahar, Nadder; Kohn, David

    2009-02-01

    We report the use of quantum dots (Qdots) as strain gages in the study of bone biomechanics using solid state nuclear magnetic resonance (NMR) spectroscopy. We have developed solid state NMR sample cells for investigation of deformations of bone tissue components at loads up to several Mega Pascal. The size constraints of the NMR instrumentation limit the bone specimen diameter and length to be no greater than 2-3 mm and 30 mm respectively. Further, magic angle spinning (MAS) solid state NMR experiments require the use of non-metallic apparatus that can be rotated at kilohertz rates. These experimental constraints preclude the use of standard biomechanical measurement systems. In this paper we explore the use of quantum dot center of gravity measurement as a strain gage technology consistent with the constraints of solid state NMR. We use Qdots that bind calcium (625 nm emission) and collagen (705 nm emission) for measurement of strain in these components. Compressive loads are applied to a specimen in a cell through a fine pitch screw turned with a mini-torque wrench. Displacement is measured as changes in the positions of arrays of quantum dots on the surface of a specimen. Arrays are created by spotting the specimen with dilute suspensions of Qdots. Mineral labeling is achieved with 705 nm carboxylated dots and matrix labeling with 565 nm quantum dots conjugated to collagen I antibodies. After each load increment the new positions of the quantum dots are measured by fluorescence microscopy. Changes in Qdot center of gravity as a function of applied load can be measured with submicron accuracy.

  16. SU-E-J-163: A Biomechanical Lung Model for Respiratory Motion Study

    SciTech Connect

    Liu, X; Belcher, AH; Grelewicz, Z; Wiersma, RD

    2015-06-15

    Purpose: This work presents a biomechanical model to investigate the complex respiratory motion for the lung tumor tracking in radiosurgery by computer simulation. Methods: The models include networked massspring-dampers to describe the tumor motion, different types of surrogate signals, and the force generated by the diaphragm. Each mass-springdamper has the same mechanical structure and each model can have different numbers of mass-spring-dampers. Both linear and nonlinear stiffness parameters were considered, and the damping ratio was tuned in a range so that the tumor motion was over-damped (no natural tumor oscillation occurs without force from the diaphragm). The simulation was run by using ODE45 (ordinary differential equations by Runge-Kutta method) in MATLAB, and all time courses of motions and inputs (force) were generated and compared. Results: The curvature of the motion time courses around their peaks was sensitive to the damping ratio. Therefore, the damping ratio can be determined based on the clinical data of a high sampling rate. The peak values of different signals and the time the peaks occurred were compared, and it was found that the diaphragm force had a time lead over the tumor motion, and the lead time (0.1–0.4 seconds) depended on the distance between the tumor and the diaphragm. Conclusion: We reported a model based analysis approach for the spatial and temporal relation between the motion of the lung tumor and the surrogate signals. Due to the phase lead of the diaphragm in comparing with the lung tumor motion, the measurement of diaphragm motion (or its electromyography signal) can be used as a beam gating signal in radiosurgery, and it can also be an additional surrogate signal for better tumor motion tracking. The research is funded by the American Cancer Society (ACS) grant. The grant name is: Frameless SRS Based on Robotic Head Motion Cancellation. The grant number is: RSG-13-313-01-CCE.

  17. Foot orthoses in the treatment of symptomatic midfoot osteoarthritis using clinical and biomechanical outcomes: a randomised feasibility study.

    PubMed

    Halstead, Jill; Chapman, Graham J; Gray, Janine C; Grainger, Andrew J; Brown, Sarah; Wilkins, Richard A; Roddy, Edward; Helliwell, Philip S; Keenan, Anne-Maree; Redmond, Anthony C

    2016-04-01

    This randomised feasibility study aimed to examine the clinical and biomechanical effects of functional foot orthoses (FFOs) in the treatment of midfoot osteoarthritis (OA) and the feasibility of conducting a full randomised controlled trial. Participants with painful, radiographically confirmed midfoot OA were recruited and randomised to receive either FFOs or a sham control orthosis. Feasibility measures included recruitment and attrition rates, practicality of blinding and adherence rates. Clinical outcome measures were: change from baseline to 12 weeks for severity of pain (numerical rating scale), foot function (Manchester Foot Pain and Disability Index) and patient global impression of change scale. To investigate the biomechanical effect of foot orthoses, in-shoe foot kinematics and plantar pressures were evaluated at 12 weeks. Of the 119 participants screened, 37 were randomised and 33 completed the study (FFO = 18, sham = 15). Compliance with foot orthoses and blinding of the intervention was achieved in three quarters of the group. Both groups reported improvements in pain, function and global impression of change; the FFO group reporting greater improvements compared to the sham group. The biomechanical outcomes indicated the FFO group inverted the hindfoot and increased midfoot maximum plantar force compared to the sham group. The present findings suggest FFOs worn over 12 weeks may provide detectable clinical and biomechanical benefits compared to sham orthoses. This feasibility study provides useful clinical, biomechanical and statistical information for the design and implementation of a definitive randomised controlled trial to evaluate the effectiveness of FFOs in treating painful midfoot OA.

  18. Biomechanics of slips.

    PubMed

    Redfern, M S; Cham, R; Gielo-Perczak, K; Grönqvist, R; Hirvonen, M; Lanshammar, H; Marpet, M; Pai, C Y; Powers, C

    2001-10-20

    The biomechanics of slips are an important component in the prevention of fall-related injuries. The purpose of this paper is to review the available literature on the biomechanics of gait relevant to slips. This knowledge can be used to develop slip resistance testing methodologies and to determine critical differences in human behaviour between slips leading to recovery and those resulting in falls. Ground reaction forces at the shoe-floor interface have been extensively studied and are probably the most critical biomechanical factor in slips. The ratio of the shear to normal foot forces generated during gait, known as the required coefficient of friction (RCOF) during normal locomotion on dry surfaces or 'friction used/achievable' during slips, has been one biomechanical variable most closely associated with the measured frictional properties of the shoe/floor interface (usually the coefficient of friction or COF). Other biomechanical factors that also play an important role are the kinematics of the foot at heel contact and human responses to slipping perturbations, often evident in the moments generated at the lower extremity joints and postural adaptations. In addition, it must be realized that the biomechanics are dependent upon the capabilities of the postural control system, the mental set of the individual, and the perception of the environment, particularly, the danger of slipping. The focus of this paper is to review what is known regarding the kinematics and kinetics of walking on surfaces under a variety of environmental conditions. Finally, we discuss future biomechanical research needs to help to improve walkway-friction measurements and safety.

  19. Open-cellular metal implant design and fabrication for biomechanical compatibility with bone using electron beam melting.

    PubMed

    Murr, L E

    2017-02-27

    Implant history extends more than 4000 years in antiquity, with biocompatible alloy implants extending over only 70 years. Over the past several decades, total hip and knee replacements of Ti-6Al-4V and Co-Cr-Mo alloys have exhibited post implantation life spans extending over 15 years; limited by infection, loosening, stress-shielding-related bone resorption and other mechanical failures. With the advent of additive manufacturing technologies, such as electron beam melting (EBM) over the past decade, personalized, patient-specific; porous (open-cellular) implant components can be manufactured, and the integration of chemical, biological and mechanical methods is able to optimize strategies for improving long-term clinical outcomes. This review outlines these strategies, which include enhanced osseointegration and vascularization prospects, and provides some evidence for, and examples of, clinical trials representative of millions of implant surgeries world-wide.

  20. Studies of Beam Dynamics in Cooler Rings

    SciTech Connect

    Dietrich, J.; Stein, J.; Meshkov, I.; Sidorin, A.; Smirnov, A.

    2006-03-20

    This report describes the numerical simulation of the crystalline proton beam formation in COSY using BETACOOL code. The study includes the description of experimental results at NAP-M storage ring where the large reduction of the momentum spread was observed for first time. The present simulation shows that this behavior of proton beam can not be explained as ordered state of protons. The numerical simulation of crystalline proton beams was done for COSY parameters. The number of protons when the ordering state can be observed is limited by value 106 particles and momentum spread less then 10-6. Experimental results for the attempt to achieve of ordered state of proton beam for COSY is presented. This work is supported by RFBR grant no. 05-02-16320 and INTAS grant no. 03-54-5584.

  1. A material sensitivity study on the accuracy of deformable organ registration using linear biomechanical models.

    PubMed

    Chi, Y; Liang, J; Yan, D

    2006-02-01

    Model-based deformable organ registration techniques using the finite element method (FEM) have recently been investigated intensively and applied to image-guided adaptive radiotherapy (IGART). These techniques assume that human organs are linearly elastic material, and their mechanical properties are predetermined. Unfortunately, the accurate measurement of the tissue material properties is challenging and the properties usually vary between patients. A common issue is therefore the achievable accuracy of the calculation due to the limited access to tissue elastic material constants. In this study, we performed a systematic investigation on this subject based on tissue biomechanics and computer simulations to establish the relationships between achievable registration accuracy and tissue mechanical and organ geometrical properties. Primarily we focused on image registration for three organs: rectal wall, bladder wall, and prostate. The tissue anisotropy due to orientation preference in tissue fiber alignment is captured by using an orthotropic or a transversely isotropic elastic model. First we developed biomechanical models for the rectal wall, bladder wall, and prostate using simplified geometries and investigated the effect of varying material parameters on the resulting organ deformation. Then computer models based on patient image data were constructed, and image registrations were performed. The sensitivity of registration errors was studied by perturbating the tissue material properties from their mean values while fixing the boundary conditions. The simulation results demonstrated that registration error for a subvolume increases as its distance from the boundary increases. Also, a variable associated with material stability was found to be a dominant factor in registration accuracy in the context of material uncertainty. For hollow thin organs such as rectal walls and bladder walls, the registration errors are limited. Given 30% in material uncertainty

  2. A material sensitivity study on the accuracy of deformable organ registration using linear biomechanical models

    SciTech Connect

    Chi, Y.; Liang, J.; Yan, D.

    2006-02-15

    Model-based deformable organ registration techniques using the finite element method (FEM) have recently been investigated intensively and applied to image-guided adaptive radiotherapy (IGART). These techniques assume that human organs are linearly elastic material, and their mechanical properties are predetermined. Unfortunately, the accurate measurement of the tissue material properties is challenging and the properties usually vary between patients. A common issue is therefore the achievable accuracy of the calculation due to the limited access to tissue elastic material constants. In this study, we performed a systematic investigation on this subject based on tissue biomechanics and computer simulations to establish the relationships between achievable registration accuracy and tissue mechanical and organ geometrical properties. Primarily we focused on image registration for three organs: rectal wall, bladder wall, and prostate. The tissue anisotropy due to orientation preference in tissue fiber alignment is captured by using an orthotropic or a transversely isotropic elastic model. First we developed biomechanical models for the rectal wall, bladder wall, and prostate using simplified geometries and investigated the effect of varying material parameters on the resulting organ deformation. Then computer models based on patient image data were constructed, and image registrations were performed. The sensitivity of registration errors was studied by perturbating the tissue material properties from their mean values while fixing the boundary conditions. The simulation results demonstrated that registration error for a subvolume increases as its distance from the boundary increases. Also, a variable associated with material stability was found to be a dominant factor in registration accuracy in the context of material uncertainty. For hollow thin organs such as rectal walls and bladder walls, the registration errors are limited. Given 30% in material uncertainty

  3. Biomechanical podiatric evaluation in an Italian cohort of patients with systemic sclerosis: A pilot study

    PubMed Central

    Maddali Bongi, Susanna; Ravenni, Giovanni; Ciampi, Benedetta; Del Rosso, Angela; El Aoufy, Khadija

    2016-01-01

    Objective Foot problems are often present in Systemic Sclerosis (SSc) patients, however studies regarding podiatric problems related to SSc are lacking and there are no data evaluating the foot biomechanical changes. The aim of the present pilot study was to evaluate podiatric problems in an Italian cohort of SSc patients by assessing received podiatric services, foot pain and disability and biomechanical foot deformity. Material and Methods 25 consecutive SSc patients were enrolled from the Division of Rheumatology, University of Florence. All SSc patients were assessed by: Standards of Care for People with Foot Musculoskeletal Health problems: Audit Tool, Foot Function Index (FFI), Weight and non-weight bearing foot joint assessment, (Foot Posture Index (FPI) and Gait Cycle), Health Assessment Questionnaire (HAQ) and Medical Outcomes Survey Short Form 36 (SF-36). Results Audit Tool - Only 7 (28%) out of the 25 patients with SSc had a specific podiatric assessment and treatment: no patient received a foot health assessment within the first 6 months of disease diagnosis and no patient received information about foot involvement. 1 patient (4%) received foot assessment every year; 1 patient (4%) received specific information about the disease and 5 patients (20%) received information about the benefits of using adapted footwear and insoles. FFI - Values of pain, disability and activity limitations, reported in FFI, are 4.7±5.1, 5.1±3.2 and 3.2±3.1 (M±DS), respectively. Non-weight bearing foot joint assessment shows a rearfoot varus deformity in 64% of patients, forefoot varus deformity in 42% and 6% forefoot valgus deformity. Weight bearing foot joint assessment, through FPI shows a pronated foot 20% of patients with and 34% with highly pronated overall foot posture. Gait analysis shows that 64% of patients has a contact of the calcaneus in invertion while 36% in eversion. In the midstance, 78% have the foot in pronation and 22% in supination, while in

  4. A numerical study of the left ventricle using structure-based bio-mechanical model

    NASA Astrophysics Data System (ADS)

    Zhu, Yunfei; Luo, Xiaoyu; Feng, Yaoqi

    A numerical study of the left ventricle using structure-based bio-mechanical model In space environment, microgravity and radiation can have deleterious effects on the cardiovascular system of the astronauts. The work in this paper is part of an ongoing effort to use mathematical models to provide a better understanding of the impact of long-duration spaceflight on the heart and blood vessels. In this study, we develop a computational left ventricle model before and after myocardium infarction based on cardiovascular mechanical theory. The anatomically realistic model has a rule-based fibre structure and a orthotropic structure-based constitutive model. The differences of deformations in the left ventricle before and after infarction are compared in details. In particular, the effects of fiber direction and fiber dispersion are examined. The disarray of both the fiber and sheet orientation is characterized by a dispersion parameter. The left ventricle volume is calculated from the MRI images and used for the optimization of the parameters of the myocardium. We provide the numerical framework for further study on effects of spaceflight on the cardiovascular system.

  5. Experimental Studies of Compensation of Beam-Beam Effects with Tevatron Electron Lenses

    SciTech Connect

    Shiltsev, V.; Alexahin, Yu.; Bishofberger, Kip; Kamerdzhiev, V.; Parkhomchuk, V.; Reva, V.; Solyak, N.; Wildman, D.; Zhang, X.-L.; Zimmermann, F.; /Fermilab /Los Alamos /Novosibirsk, IYF /CERN

    2008-02-01

    Applying the space-charge forces of a low-energy electron beam can lead to a significant improvement of the beam-particle lifetime limit arising from the beam-beam interaction in a high-energy collider [1]. In this article we present the results of various beam experiments with 'electron lenses', novel instruments developed for the beam-beam compensation at the Tevatron, which collides 980-GeV proton and antiproton beams. We study the dependencies of the particle betatron tunes on the electron beam current, energy and position; we explore the effects of electron-beam imperfections and noises; and we quantify the improvements of the high-energy beam intensity and the collider luminosity lifetime obtained by the action of the Tevatron Electron Lenses.

  6. 6-D weak-strong beam-beam simulation study of proton lifetime in presence of head-on beam-beam compensation in the RHIC

    SciTech Connect

    Luo, Y.; Fischer, W.

    2010-08-01

    In this note we summarize the calculated particle loss of a proton bunch in the presence of head-on beam-beam compensation in the Relativistic Heavy Ion Collider (RHIC). To compensate the head-on beam-beam effect in the RHIC 250 GeV polarized proton run, we are introducing a DC electron beam with the same transverse profile as the proton beam to collide with the proton beam. Such a device is called an electron lens (e-lens). In this note we first present the optics and beam parameters and the tracking setup. Then we calculate and compare the particle loss of a proton bunch with head-on beam-beam compensation, phase advance of k{pi} between IP8 and the center of the e-lens and second order chromaticity correction. We scanned the proton beam's linear chromaticity, working point and bunch intensity. We also scanned the electron beam's intensity, transverse beam size. The effect of the electron-proton transverse offset in the e-lens was studied. In the study 6-D weak-strong beam-beam interaction model a la Hirata is used for proton collisions at IP6 and IP8. The e-lens is modeled as 8 slices. Each slice is modeled with as drift - (4D beam-beam kick) - drift.

  7. Prospective Study of the Relation between Landing Biomechanics and Jumper's Knee.

    PubMed

    der Worp, H van; van der Does, H T D; Brink, M S; Zwerver, J; Hijmans, J M

    2016-03-01

    The literature on the relation between jump biomechanics and jumper's knee indicates that a jump with horizontal displacement poses a threat for developing jumper's knee. Subjects with jumper's knee have been shown to display a stiff landing pattern characterized by a small range of motion. However, up to now only cross-sectional studies have been conducted. 6 teams from sports involving repetitive landing were followed prospectively for 2 years. At baseline athletes performed the Landing Error Scoring System jump and 3D kinematics and kinetics were obtained. A comparison was made between subjects who developed jumper's knee and those who did not develop it. 3 subjects developed jumper's knee during the study. Leg stiffness during landing was high compared to the mean of the healthy controls. No common kinematic patterns could be identified in these 3 subjects. The results suggest that athletes with high leg stiffness during landing might have an increased risk for developing jumper's knee, yet this conclusion is based on a very small sample. Subjects who develop jumper's knee do not show a common landing technique. Further research is needed to investigate whether leg stiffness can be used to identify athletes at risk and as a target variable to be used in prevention.

  8. A comparative biomechanical study of bone ingrowth in two porous hydroxyapatite bioceramics

    NASA Astrophysics Data System (ADS)

    Ren, Li-Mei; Todo, Mitsugu; Arahira, Takaaki; Yoshikawa, Hideki; Myoui, Akira

    2012-12-01

    Calcium phosphate-based bioceramics have been widely used as artificial bone substitute materials because of their superior biocompatibility and osteoconductivity. In the present study, mechanical properties changes of two hydroxyapatite (HA) ceramics induced by bone ingrowth were tested and evaluated in a rabbit model. Both materials (NEOBONE®, Apaceram-AX®) have highly interconnected pores with a porosity of 75-85%. The major structural difference between them lies in that Apaceram-AX® has micropores smaller than 10 micrometers in diameter, whereas NEOBONE® does not contain such micropores. Both materials were implanted into the femoral condyles of rabbits for the specified observation period (1, 5, 12, 24, and 48 weeks) and then evaluated by experimental approach in combination with finite element method (FEM). Results indicate that two porous bioceramics exhibit different degradability in vivo, and remarkably different variation of total stiffness, elastic modulus distribution, as well as strain energy density distribution calculated by FE simulation. These results demonstrate how the internal microstructures affect the progress of bone regeneration and mechanical properties with the duration of implantation, emphasizing the importance of biomaterial design tailored to various clinic applications. Additionally, this study showed a potential for applying the computational method to monitor the time-dependent biomechanical changes of implanted porous bioceramics.

  9. Gastrocsoleus recession techniques: an anatomical and biomechanical study in human cadavers.

    PubMed

    Tinney, A; Khot, A; Eizenberg, N; Wolfe, R; Graham, H K

    2014-06-01

    Lengthening of the conjoined tendon of the gastrocnemius aponeurosis and soleus fascia is frequently used in the treatment of equinus deformities in children and adults. The Vulpius procedure as described in most orthopaedic texts is a division of the conjoined tendon in the shape of an inverted V. However, transverse division was also described by Vulpius and Stoffel, and has been reported in some clinical studies. We studied the anatomy and biomechanics of transverse division of the conjoined tendon in 12 human cadavers (24 legs). Transverse division of the conjoined tendon resulted in predictable, controlled lengthening of the gastrocsoleus muscle-tendon unit. The lengthening achieved was dependent both on the level of the cut in the conjoined tendon and division of the midline raphé. Division at a proximal level resulted in a mean lengthening of 15.2 mm (sd 2.0, (12 to 19), which increased to 17.1 mm (sd 1.8, (14 to 20) after division of the midline raphé. Division at a distal level resulted in a mean lengthening of 21.0 mm (sd 2.0, (18 to 25), which increased to 26.4 mm (sd 1.4, (24 to 29) after division of the raphé. These differences were significant (p < 0.001).

  10. Topography of acoustical properties of long bones: from biomechanical studies to bone health assessment.

    PubMed

    Tatarinov, Alexey; Sarvazyan, Armen

    2008-01-01

    The article presents a retrospective view on the assessment of long bones condition using topographical patterns of the acoustic properties. The application of ultrasonic point-contact transducers with exponential waveguides on a short acoustic base for detailed measurements in human long bones by the surface transmission was initiated during the 1980s in Latvia. The guided wave velocity was mapped on the surface of the long bones and the topographical patterns reflected the biomechanical peculiarities. Axial velocity profiles obtained in vivo by measurements along the medial surface of tibia varied due to aging, hypokinesia, and physical training. The method has been advanced at Artann Laboratories (West Trenton, NJ) by the introduction of multifrequency data acquisition and axial scanning. The model studies carried out on synthetic phantoms and in bone specimens confirmed the potential to evaluate separately changes of the bone material properties and of the cortical thickness by multifrequency acoustic measurements at the 0.1 to 1 MHz band. The bone ultrasonic scanner (BUSS) is an axial mode ultrasonometer developed to depict the acoustic profile of bone that will detect the onset of bone atrophy as a spatial process. Clinical trials demonstrated a high sensitivity of BUSS to osteoporosis and the capability to assess early stage of osteopenia.

  11. Topography of Acoustical Properties of Long Bones: From Biomechanical Studies to Bone Health Assessment

    PubMed Central

    Tatarinov, Alexey; Sarvazyan, Armen

    2010-01-01

    The article presents a retrospective view on the assessment of long bones condition using topographical patterns of the acoustic properties. The application of ultrasonic point-contact transducers with exponential waveguides on a short acoustic base for detailed measurements in human long bones by the surface transmission was initiated during the 1980s in Latvia. The guided wave velocity was mapped on the surface of the long bones and the topographical patterns reflected the biomechanical peculiarities. Axial velocity profiles obtained in vivo by measurements along the medial surface of tibia varied due to aging, hypokinesia, and physical training. The method has been advanced at Artann Laboratories (West Trenton, NJ) by the introduction of multifrequency data acquisition and axial scanning. The model studies carried out on synthetic phantoms and in bone specimens confirmed the potential to evaluate separately changes of the bone material properties and of the cortical thickness by multifrequency acoustic measurements at the 0.1 to 1 MHz band. The bone ultrasonic scanner (BUSS) is an axial mode ultrasonometer developed to depict the acoustic profile of bone that will detect the onset of bone atrophy as a spatial process. Clinical trials demonstrated a high sensitivity of BUSS to osteoporosis and the capability to assess early stage of osteopenia. PMID:18599416

  12. A biomechanical study on fixation stability with twin hook or lag screw in artificial cancellous bone.

    PubMed

    Olsson, O; Tanner, K E; Ceder, L; Ryd, L

    2002-01-01

    The twin hook has been developed as an alternative to the conventional lag screw to be combined with a barrelled side-plate in the treatment of trochanteric hip fractures. With two oppositely directed apical hooks introduced into the subchondral bone of the femoral head, the twin hook provides different stabilising properties to the lag screw. The femoral head purchase of the twin hook and the lag screw were compared in a biomechanical study using artificial cancellous bone, and responses to axial and torsional loading was determined. A distinct yield point in load and torque was noted for the lag screw, representing failure of the laminas supporting the threads. For the twin hook, gradual increase of load and torque occurred during impaction of the bone supporting the hooks. The peak loads and torques were higher for the lag screw, but were similar for both devices after 8 mm deformation. The stiffness was higher for the lag screw, but in counter-clockwise rotation the stiffness for the lag screw was negligible. The twin hook appeared to provide fixation stability comparable to that offered by the lag screw, but with conceivable advantages in terms of a deformation response involving bone impaction and gradually increasing stability.

  13. Biomechanical effect of increasing or decreasing degrees of freedom for surgery of trapeziometacarpal joint arthritis: a simulation study.

    PubMed

    Domalain, Mathieu F; Seitz, William H; Evans, Peter J; Li, Zong-Ming

    2011-11-01

    Osteoarthritis of the trapeziometacarpal (TMC) joint can be treated by arthrodesis and arthroplasty, which potentially decreases or increases the degrees of freedom (DoF) of the joint, respectively. The aim of our study was to bring novel biomechanical insights into these joint surgery procedures by investigating the influence of DoF at the TMC joint on muscle and joint forces in the thumb. A musculoskeletal model of the thumb was developed to equilibrate a 1 N external force in various directions while the thumb assumed key and pulp pinch postures. Muscle and joint forces were computed with an optimization method. In comparison to that of the 2-DoF (intact joint) condition, muscle forces slightly decreased in the 0-DoF (arthrodesis) condition, but drastically increased in the 3-DoF (arthroplasty) condition. TMC joint forces in the 3-DoF condition were 12 times larger than the 2-DoF joint. This study contributes to a further understanding of the biomechanics of the intact and surgically repaired TMC joint and addresses the biomechanical consequences of changing a joint's DoF by surgery. 

  14. A biomechanical study of 3 different types of sublaminar wire used for constructs in the thoracic spine.

    PubMed

    Murakami, Hideki; Yamazaki, Ken; Attallah-Wasif, Emad S; Tsai, Kai-Jow; Shimamura, Tadashi; Hutton, William C

    2006-08-01

    A biomechanical study was carried out on 3 different types of sublaminar wire used in constructs to secure the thoracic spine: stainless steel monofilament wire (steel wire), titanium cable (cable), and ultra-high molecular weight polyethylene tape (tape). Two experiments were carried out. Experiment 1: Thirty-one fresh human thoracic vertebrae classified as osteoporotic (bone mineral density of <0.8 g/cm2) were used. The steel wire, cable, or tape was placed sublaminarly and a tensile force was applied until the steel wire, cable, or tape cut 5 mm through the lamina, and the force at this point was noted. Experiment 2: Seven fresh human thoracic spines (T7-T10) were biomechanically tested as follows: axial compression (250 N), flexion (7.5 Nm), extension (7.5 Nm), left lateral bending (7.5 Nm), right lateral bending (7.5 Nm), left axial torsion (10 Nm), and right axial torsion (10 Nm). This sequence was applied to the intact spine. The spine was then de-stabilized and then restabilized using one or other of the 3 different types of sublaminar wires. The biomechanical testing was then repeated on the restabilized spine and stiffness curves were generated. In the laminar cut-through test, the cut-through force for tape was higher than that for either steel wire or cable. In the biomechanical stiffness testing, there was no significant difference between the 3 different sublaminar wiring constructs in any of the loading modes tested. The results of both experiments suggest that tape is as good, if not better, than steel wire or cable as a sublaminar wiring construct material.

  15. Preliminary Biomechanical Study of Different Acetabular Reinforcement Devices for Acetabular Reconstruction

    PubMed Central

    Tai, Ching-Lung; Lee, Po-Yi; Hsieh, Pang-Hsing

    2015-01-01

    Background Acetabular reinforcement devices (ARDs) are frequently used as load-sharing devices to allow allograft incorporation in revision hip arthroplasty with massive acetabular bone loss. The key to a successful reconstruction is robust fixation of the device to the host acetabulum. Interlocking fixation is expected to improve the initial stability of the postoperative construct. However, all commercially available ARDs are designed with non-locking fixation. This study investigates the efficacy of standard ARDs modified with locking screw mechanisms for improving stability in acetabular reconstruction. Methods Three types of ARDs were examined to evaluate the postoperative compression and angular stability: i) standard commercial ARDs, ii) standard ARDs modified with monoaxial and iii) standard ARDs modified with polyaxial locking screw mechanisms. All ARDs were implanted into osteomized synthetic pelvis with pelvic discontinuity. Axial compression and torsion tests were then performed using a servohydraulic material testing machine that measured load (angle) versus displacement (torque). Initial stability was compared among the groups. Results Equipping ARDs with interlocking mechanisms effectively improved the initial stability at the device/bone interface compared to standard non-locked ARDs. In both compression and torsion experiments, the monoaxial interlocking construct demonstrated the highest construct stiffness (672.6 ± 84.1 N/mm in compression and 13.3 ± 1.0 N·m/degree in torsion), whereas the non-locked construct had the lowest construct stiffness (381.4 ± 117.2 N/mm in compression and 6.9 ± 2.1 N·m/degree in torsion) (P < 0.05). Conclusions Our study demonstrates the potential benefit of adding a locking mechanism to an ARD. Polyaxial ARDs provide the surgeon with more flexibility in placing the screws at the cost of reduced mechanical performance. This in vitro study provides a preliminary evaluation of biomechanical performance for ARDs

  16. Gamma Putty dosimetric studies in electron beam

    PubMed Central

    Gloi, Aime M.

    2016-01-01

    Traditionally, lead has been used for field shaping in megavoltage electron beams in radiation therapy. In this study, we analyze the dosimetric parameters of a nontoxic, high atomic number (Z = 83), bismuth-loaded material called Gamma Putty that is malleable and can be easily molded to any desired shape. First, we placed an ionization chamber at different depths in a solid water phantom under a Gamma Putty shield of thickness (t = 0, 3, 5, 10, 15, 20, and 25 mm, respectively) and measured the ionizing radiation on the central axis (CAX) for electron beam ranging in energies from 6 to 20 MeV. Next, we investigated the relationship between the relative ionization (RI) measured at a fixed depth for several Gamma Putty shield at different cutout diameters ranging from 2 to 5 cm for various beam energies and derived an exponential fitting equation for clinical purposes. The dose profiles along the CAX show that bremsstrahlung dominates for Gamma Putty thickness >15 mm. For high-energy beams (12–20 MeV) and all Gamma Putty thicknesses up to 25 mm, RI below 5% could not be achieved due to the strong bremsstrahlung component. However, Gamma Putty is a very suitable material for reducing the transmission factor below 5% and protecting underlying normal tissues for low-energy electron beams (6–9 MeV). PMID:27651563

  17. The Relationship between MR Parameters and Biomechanical Quantities of Loaded Human Articular Cartilage in Osteoarthritis: An In-Vitro Study

    NASA Astrophysics Data System (ADS)

    Juráš, V.; Szomolányi, P.; Gäbler, S.; Frollo, I.; Trattnig, S.

    2009-01-01

    The aim of this study was to assess the changes in MRI parameters during applied load directly in MR scanner and correlate these changes with biomechanical parameters of human articular cartilage. Cartilage explants from patients who underwent total knee replacement were examined in the micro-imaging system in 3T scanner. Respective MRI parameters (T1 without- and T1 with contrast agent as a marker of proteoglycan content, T2 as a marker of collagen network anisotropy and ADC as a measure of diffusivity) were calculated in pre- and during compression state. Subsequently, these parameters were compared to the biomechanical properties of articular cartilage, instantaneous modulus (I), equilibrium modulus (Eq) and time of tissue relaxation (τ). Significant load-induced changes of T2 and ADC were recorded. High correlation between T1Gd and I (r = 0.6324), and between ADC and Eq (r = -0.4884) was found. Multi-parametric MRI may have great potential in analyzing static and dynamic biomechanical behavior of articular cartilage in early stages of osteoarthritis (OA).

  18. Visualisation to enhance biomechanical tuning of ankle-foot orthoses (AFOs) in stroke: study protocol for a randomised controlled trial

    PubMed Central

    2011-01-01

    Background There are a number of gaps in the evidence base for the use of ankle-foot orthoses for stroke patients. Three dimensional motion analysis offers an ideal method for objectively obtaining biomechanical gait data from stroke patients, however there are a number of major barriers to its use in routine clinical practice. One significant problem is the way in which the biomechanical data generated by these systems is presented. Through the careful design of bespoke biomechanical visualisation software it may be possible to present such data in novel ways to improve clinical decision making, track progress and increase patient understanding in the context of ankle-foot orthosis tuning. Methods A single-blind randomised controlled trial will be used to compare the use of biomechanical visualisation software in ankle-foot orthosis tuning against standard care (tuning using observation alone). Participants (n = 70) will have experienced a recent hemiplegia (1-12 months) and will be identified by their care team as being suitable candidates for a rigid ankle-foot orthosis. The primary outcome measure will be walking velocity. Secondary outcome measures include; lower limb joint kinematics (thigh and shank global orientations) & kinetics (knee and hip flexion/extension moments, ground reaction force FZ2 peak magnitude), step length, symmetry ratio based on step length, Modified Ashworth Scale, Modified Rivermead Mobility Index and EuroQol (EQ-5D). Additional qualitative measures will also be taken from participants (patients and clinicians) at the beginning and end of their participation in the study. The main aim of the study is to determine whether or not the visualisation of biomechanical data can be used to improve the outcomes of tuning ankle-foot orthoses for stroke patients. Discussion In addition to answering the primary research question the broad range of measures that will be taken during this study are likely to contribute to a wider understanding of

  19. [A complex study of the movement biomechanics in patients with post-stroke hemiparesis].

    PubMed

    Skvortsov, D V; Bulatova, M A; Kovrazhkina, E A; Suvorov, A Iu; Ivanova, G E; Skvortsova, V I

    2012-01-01

    The authors present results of a pilot study on biomechanics of non-cyclic movements of the human consequent verticalization in the ontogenesis of patients with post-stroke hemiparesis (10 patients in the acute stage of cerebral stroke) and 10 healthy volunteers without neurologic and orthopedic pathology. Some movements of therapeutic exercises Balance (a model of ontogenetic kinesitherapy) have been selected for the study. Cinematic parameters have been recorded using a system of motion 3D video analysis, a kinematic model was build in accordance to standard protocols. The skin (native and straightened) electromyogram (EMG) was recorded synchronously with kinematic data using 16-channel electromyography from the following pairs of muscles: mm. sternocleido-mastoideus, trapezius (горизонтальная порция), biceps brachii, triceps brachii, rectus femoris, adductor magnus. Major differences in the EMG picture between patients and controls were: 1) the EMG "monotony" with the involvement of multiple additional muscles in locomotions with the prevalence of the peculiar "tonic" muscle activity (low amplitudes without distinct peaks), stretching along the whole cycle of movement. In controls, EMG demonstrated variability and had mostly "phasic" character with distinct 1 or 2 peaks; 2) the asymmetry of EMG profile in symmetric movements. i.e. when performed simultaneously from the right and from the left sides. The latter feature may be considered as predictive because it was never found in healthy people. It allows to identify objectively weak muscles even in the absence of visible parethis during the routine neurological examination.

  20. Biomechanical and morphological study of a new elastic mesh (Ciberlastic) to repair abdominal wall defects.

    PubMed

    Calvo, B; Pascual, G; Peña, E; Pérez-Khöler, B; Rodríguez, M; Bellón, J M

    2016-06-01

    The aim of this study was to conduct a preclinical evaluation of the behaviour of a new type of abdominal LW prosthesis (Ciberlastic), which was designed with a non-absorbable elastic polyurethane monofilament (Assuplus, Assut Europe, Italy) to allow greater adaptability to mechanical area requirements and higher bio-mimicking with the newly formed surrounding tissues. Our hypothesis was that an increase in the elasticity of the mesh filament could improve the benefits of LW prostheses. To verify our hypothesis, we compared the short- and long-term behaviour of Ciberlastic and Optilene(®) elastic commercial meshes by repairing the partially herniated abdomen in New Zealand White rabbits. The implanted meshes were mechanically and histologically assessed at 14 and 180 days post-implant. We mechanically characterized the partially herniated repaired muscle tissue and also determined mesh shrinkage at different post-implant times. This was followed by a histological study in which the tissue incorporation process was analysed over time. The new prosthesis designed by our group achieved good behaviour that was similar to that of Optilene(®), one of the most popular LW prostheses on the market, with the added advantage of its elastic property. The mechanical properties are significantly lower than those of the polypropylene Optilene(®) mesh, and the new elastic mesh meets the basic mechanical requirements for positioning in the abdominal wall, which was also demonstrated by the absence of recurrences after implantation in the experimental model. We found that the growth of a connective tissue rich in collagen over the hernial defect and the proper deposit of the collagen fibres in the regenerated tissue substantially modified the original properties of the mesh, thereby increasing its biomechanical strength and making the whole tissue/mesh stiffer.

  1. Shoulder biomechanics.

    PubMed

    Lugo, Roberto; Kung, Peter; Ma, C Benjamin

    2008-10-01

    The biomechanics of the glenohumeral joint depend on the interaction of both static and dynamic-stabilizing structures. Static stabilizers include the bony anatomy, negative intra-articular pressure, the glenoid labrum, and the glenohumeral ligaments along with the joint capsule. The dynamic-stabilizing structures include the rotator cuff muscles and the other muscular structures surrounding the shoulder joint. The combined effect of these stabilizers is to support the multiple degrees of motion within the glenohumeral joint. The goal of this article is to review how these structures interact to provide optimal stability and how failure of some of these mechanisms can lead to shoulder joint pathology.

  2. Improved wire stiffness with modified connection bolts in Ilizarov external frames: a biomechanical study.

    PubMed

    Gessmann, Jan; Jettkant, Birger; Königshausen, Matthias; Schildhauer, Thomas Armin; Seybold, Dominik

    2012-01-01

    Frame stability in Ilizarov external fixators is mainly dependent on the tension of the transosseous wires, which are clamped to the ring by connection bolts. It was the purpose of this biomechanical study to investigate the holding capacity of a modified bolt design featuring a ruffled wire-bolt interface (TrueLok™) and its influence on wire stiffness in comparison with that of classic bolts featuring a smooth, unruffled wire-bolt interface. Six different ring and bolt configurations were tested using a simplified model consisting of a single ring and wire. The holding capacity at two different tightening torques (10 and 14 Nm) of classic cannulated bolts (CB) and slotted bolts (SB) was determined on Ilizarov and Taylor Spatial Frame (TSF™) rings, whereas the modified TrueLok™ CBs and SBs were used with the TrueLok™ rings. The wire stiffness was calculated via a regression analysis of the load-displacement graphs. The modified TrueLok™ bolts demonstrated significantly better slippage resistance than the classic bolts in all configurations and wire stiffness was significantly higher in the TrueLok™ frame set-ups. After maximum loading, all of the wires showed plastic deformation, including constant wire deflection and dent marks at the clamped wire ends. In conclusion, the decrease in wire stiffness can be explained mainly as a result of wire slippage, but plastic deformation and material yielding also contribute. The relatively simple modification made by roughening the wire-bolt interface results in improved holding capacity and wire stiffness. A frame that contains these modified TrueLok™ bolts should provide improved mechanical stiffness.

  3. Effects of a contoured articular prosthetic device on tibiofemoral peak contact pressure: a biomechanical study

    PubMed Central

    Huber, Roland; Thermann, Hajo; Paessler, Hans H.; Skrbensky, Gobert

    2007-01-01

    Many middle-aged patients are affected by localized cartilage defects that are neither appropriate for primary, nor repeat biological repair methods, nor for conventional arthroplasty. This in vitro study aims to determine the peak contact pressure in the tibiofemoral joint with a partial femoral resurfacing device (HemiCAP®, Arthrosurface Inc., Franklin, MA, USA). Peak contact pressure was determined in eight fresh-frozen cadaveric specimens using a Tekscan sensor placed in the medial compartment above the menisci. A closed loop robotic knee simulator was used to test each knee in static stance positions (5°/15°/30°/45°) with body weight ground reaction force (GRF), 30° flexion with twice the body weight (2tBW) GRF and dynamic knee-bending cycles with body weight GRF. The ground reaction force was adjusted to the living body weight of the cadaver donor and maintained throughout all cycles. Each specimen was tested under four different conditions: Untreated, flush HemiCAP® implantation, 1-mm proud implantation and 20-mm defect. A paired sampled t test to compare means (significance, P ≤ 0.05) was used for statistical analysis. On average, no statistically significant differences were found in any testing condition comparing the normal knee with flush device implantation. With the 1-mm proud implant, statistically significant increase of peak contact pressures of 217% (5° stance), 99% (dynamic knee bending) and 90% (30° stance with 2tBW) compared to the untreated condition was seen. No significant increase of peak contact pressure was evaluated with the 20-mm defect. The data suggests that resurfacing with the HemiCAP® does not lead to increased peak contact pressure with flush implantation. However, elevated implantation results in increased peak contact pressure and might be biomechanically disadvantageous in an in vivo application. PMID:17934718

  4. [Study of the immediate biomechanical stability in a goat cervical spine model].

    PubMed

    Li, Xiaohui; Zhou, Chunguang; Song, Yueming

    2009-10-01

    A new kind of Cage made of poly-DL-lactic acid was designed and an in-vitro study was conducted to evaluate the biomechanical effect of PDLLA Cage on a goat cervical spine model. 27 goat cervical spines were divided into four groups randomly: intact group, PDLLA Cage group, titanium Cage group, and autologous tricortical iliac crest bone group. Different implants were implanted after complete discectomy (C3-4) was performed, then they were tested in flexion, extension, axial rotation, and lateral bending with a nondestructive stiffness method using a nonconstrained testing apparatus, and three-dimensional displacement was measured. The range of motion (ROM) and the mean stiffness values were calculated and compared between groups. The result showed that the ROM values between PDLLA Cage group and the titanium Cage group were not significantly different in extensional and rotational movement (P > 0.05), but they were lower than that of rest groups (P < 0.05). In flexional loading mode, the ROM values showed statistically significant difference between the four groups (P < 0.05). And in lateral bending loading mode, no significant difference was found between PDLLA Cage group and iliac crest bone group (P > 0.05), but significant difference was found among the other groups (P < 0.05). The stiffness of cervical spine was raised after Cage was implanted. In flexional and rotational loading mode, significant difference in stiffness was found between PDLLA Cage group and control group or iliac crest bone group (P < 0.05). So PDLLA Cage can provide enough primary stability for cervical intervertebral fusion.

  5. Double plating in Vancouver type B1 periprosthetic proximal femur fractures: A biomechanical study.

    PubMed

    Wähnert, Dirk; Grüneweller, Niklas; Gehweiler, Dominic; Brunn, Benjamin; Raschke, Michael J; Stange, Richard

    2017-02-01

    Periprosthetic hip fractures are an increasing problem in modern orthopedic and trauma surgery. Many options for the operative treatment are available to the surgeon ranging from modern variable angular systems to standard plates, screws, and cerclages. However, there is no gold standard and therefore, the aim of this study, was to investigate the biomechanical characteristics of double plating versus a lateral standard plate in a Vancouver B1 fracture model. Ten 4th generation composite femora were used to implant cementless total hip prosthesis and create Vancouver B1 periprosthetic fractures. Afterwards, the osteotomies were fixed using the locking compression plate in combination with the locking attachment plate (LCP, LAP, DePuy Synthes, Solothurn, Switzerland)-group I. Group II additionally achieved a 5-hole 4.5/5.0 mm LCP anteriorly. Each construct was cyclically loaded to failure in axial compression. Axial construct stiffness was 50.87 N/mm (SD 1.61) for group I compared to 738.68 N/mm (SD 94.8) for group II, this difference was statistically significant (p = 0.016). The number of cycles to failure was also significant higher for group II (2,375 vs. 13,000 cycles; p = 0.016). Double plating can significantly increase construct stiffness and stability, and thus, is an option in the treatment of complex periprosthetic fractures, in revision surgery and for patients with the inability to partial weight bear. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:234-239, 2017.

  6. Beamed-Energy Propulsion (BEP) Study

    NASA Technical Reports Server (NTRS)

    George, Patrick; Beach, Raymond

    2012-01-01

    The scope of this study was to (1) review and analyze the state-of-art in beamed-energy propulsion (BEP) by identifying potential game-changing applications, (2) formulate a roadmap of technology development, and (3) identify key near-term technology demonstrations to rapidly advance elements of BEP technology to Technology Readiness Level (TRL) 6. The two major areas of interest were launching payloads and space propulsion. More generally, the study was requested and structured to address basic mission feasibility. The attraction of beamed-energy propulsion (BEP) is the potential for high specific impulse while removing the power-generation mass. The rapid advancements in high-energy beamed-power systems and optics over the past 20 years warranted a fresh look at the technology. For launching payloads, the study concluded that using BEP to propel vehicles into space is technically feasible if a commitment to develop new technologies and large investments can be made over long periods of time. From a commercial competitive standpoint, if an advantage of beamed energy for Earth-to-orbit (ETO) is to be found, it will rest with smaller, frequently launched payloads. For space propulsion, the study concluded that using beamed energy to propel vehicles from low Earth orbit to geosynchronous Earth orbit (LEO-GEO) and into deep space is definitely feasible and showed distinct advantages and greater potential over current propulsion technologies. However, this conclusion also assumes that upfront infrastructure investments and commitments to critical technologies will be made over long periods of time. The chief issue, similar to that for payloads, is high infrastructure costs.

  7. [Researches in forensic biomechanics].

    PubMed

    Xu, Yan; Fan, Yubo; Yu, Xiaojun

    2004-02-01

    Forensic biomechanics is the science of proof, which applies the biomechanical theory and technology to resolve problems related to mechanics in the process of expert witness. It belongs to the realm of a new subject combining biomechanics and forensics. Forensic biomechanics is a new branch of modern biomechanics and at the same time a new important branch of forensics, and it is one of the most potential research areas in forensics of injury. In this paper, the task of forensic biomechanics expert witness, the procedure of expert witness, and the forensic biomechanics research methods and cases are reviewed.

  8. Evaluation of Stability of Rotating Hinge Knee Prostheses: A Biomechanical Study

    PubMed Central

    Friesenbichler, Joerg; Leithner, Andreas; Glehr, Mathias; Sadoghi, Patrick; Maurer-Ertl, Werner; Avian, Alexander

    2013-01-01

    Purpose. Rotating hinge knee prostheses should provide a stable situation following reconstruction. We performed a biomechanical analysis to establish the association between design of the central rotational stem (peg) and implant's stability, in a theoretical setting. Methods. Six different rotating hinge designs were tested, and three observers performed two different measurements with a custom made biomechanical apparatus and laterally directed pressure. The aim was to assign the degree of tilting of the peg within the vertical post-in channel by extending the distraction as well as the maximum amount of distraction before the peg's dislocation. An intraclass-correlation coefficient (ICC) was calculated to determine the observer's reliability. Results. Implant designs with cylindrical pegs of different lengths were superior to implant designs with conical or other shaped pegs concerning stability and maximum amount of distraction before dislocation, showing steep rising distraction-angular displacement curves. The ICC at 15 mm and 25 mm of distraction revealed high interobserver reliability (P < 0.001). Conclusion. The biomechanical analysis showed that rotating hinge prostheses with long and cylindrical pegs have the highest stability at any given amount of distraction. Designs with shorter and markedly tapered pegs may become unstable under conditions of mild joint distraction which has to be proven in future in vivo investigations. PMID:24967114

  9. Beam-Beam Study on the Upgrade of Beijing Electron Positron Collider

    SciTech Connect

    Wang, S.; Cai, Y.; /SLAC

    2006-02-10

    It is an important issue to study the beam-beam interaction in the design and performance of such a high luminosity collider as BEPCII, the upgrade of Beijing Electron Positron Collider. The weak-strong simulation is generally used during the design of a collider. For performance a large scale tune scan, the weak-strong simulation studies on beam-beam interaction were done, and the geometry effects were taken into account. The strong-strong simulation studies were done for investigating the luminosity goal and the dependence of the luminosity on the beam parameters.

  10. Beam structure and transverse emittance studies of high-energy ion beams

    NASA Astrophysics Data System (ADS)

    Saadatmand, K.; Johnson, K. F.; Schneider, J. D.

    1991-05-01

    A visual diagnostic technique was developed to monitor and study ion beam structure shape and size along a transport line. In this technique, a commercially available fluorescent screen is utilized in conjunction with a video camera. This visual representation of the beam structure is digitized and enhanced through use of false color coding and displayed on a TV monitor for on-line viewing. Digitized information is stored for further off-line processing (e.g., extraction of beam profiles). An optional wire grid placed upstream of the fluor screen adds the capability of transverse emittance (or angular spread) measurement to this technique. This diagnostic allows real time observation of the beam response to parameter changes (e.g., evolution of the beam structure, shifts in the beam intensity at various spatial locations within the beam perimeter, and shifts in the beam center and position).

  11. Biomechanics of fibrous proteins of the extracellular matrix studied by Brillouin scattering

    PubMed Central

    Palombo, Francesca; Winlove, C. Peter; Edginton, Ryan S.; Green, Ellen; Stone, Nick; Caponi, Silvia; Madami, Marco; Fioretto, Daniele

    2014-01-01

    Brillouin light scattering (BLS) spectroscopy is a technique that is able to detect thermally excited phonons within a material. The speed of propagation of these phonons can be determined from the magnitude of the Brillouin frequency shift between incident and scattered light, thereby providing a measure of the mechanical properties of the material in the gigahertz range. The mechanical properties of the extracellular matrices of biological tissues and their constituent biopolymers are important for normal tissue function and disturbances in these properties are widely implicated in disease. BLS offers the prospect of measuring mechanical properties on a microscopic scale in living tissues, thereby providing insights into structure–function relationships under normal and pathological conditions. In this study, we investigated BLS in collagen and elastin—the fibrous proteins of the extracellular matrix (ECM). Measurements were made on type I collagen in rat tail tendon, type II collagen in articular cartilage and nuchal ligament elastin. The dependence of the BLS spectrum on fibre orientation was investigated in a backscattering geometry using a reflective substrate. Two peaks, a bulk mode arising from phonon propagation along a quasi-radial direction to the fibre axis and a mode parallel to the surface, depending on sample orientation relative to the fibre axis, could be distinguished. The latter peak was fitted to a model of wave propagation through a hexagonally symmetric elastic solid, and the five components of the elasticity tensor were combined to give axial and transverse Young's, shear and bulk moduli of the fibres. These were 10.2, 8.3, 3.2 and 10.9 GPa, and 6.1, 5.3, 1.9 and 8 GPa for dehydrated type I collagen and elastin, respectively. The former values are close to those previously reported. A microfocused BLS approach was also applied providing selection of single fibres. The moduli of collagen and elastin are much higher than those measured at

  12. Biomechanics of fibrous proteins of the extracellular matrix studied by Brillouin scattering.

    PubMed

    Palombo, Francesca; Winlove, C Peter; Edginton, Ryan S; Green, Ellen; Stone, Nick; Caponi, Silvia; Madami, Marco; Fioretto, Daniele

    2014-12-06

    Brillouin light scattering (BLS) spectroscopy is a technique that is able to detect thermally excited phonons within a material. The speed of propagation of these phonons can be determined from the magnitude of the Brillouin frequency shift between incident and scattered light, thereby providing a measure of the mechanical properties of the material in the gigahertz range. The mechanical properties of the extracellular matrices of biological tissues and their constituent biopolymers are important for normal tissue function and disturbances in these properties are widely implicated in disease. BLS offers the prospect of measuring mechanical properties on a microscopic scale in living tissues, thereby providing insights into structure-function relationships under normal and pathological conditions. In this study, we investigated BLS in collagen and elastin-the fibrous proteins of the extracellular matrix (ECM). Measurements were made on type I collagen in rat tail tendon, type II collagen in articular cartilage and nuchal ligament elastin. The dependence of the BLS spectrum on fibre orientation was investigated in a backscattering geometry using a reflective substrate. Two peaks, a bulk mode arising from phonon propagation along a quasi-radial direction to the fibre axis and a mode parallel to the surface, depending on sample orientation relative to the fibre axis, could be distinguished. The latter peak was fitted to a model of wave propagation through a hexagonally symmetric elastic solid, and the five components of the elasticity tensor were combined to give axial and transverse Young's, shear and bulk moduli of the fibres. These were 10.2, 8.3, 3.2 and 10.9 GPa, and 6.1, 5.3, 1.9 and 8 GPa for dehydrated type I collagen and elastin, respectively. The former values are close to those previously reported. A microfocused BLS approach was also applied providing selection of single fibres. The moduli of collagen and elastin are much higher than those measured at lower

  13. Biomechanical evaluation of an integrated fixation cage during fatigue loading: a human cadaver study.

    PubMed

    Palepu, Vivek; Peck, Jonathan H; Simon, David D; Helgeson, Melvin D; Nagaraja, Srinidhi

    2017-04-01

    OBJECTIVE Lumbar cages with integrated fixation screws offer a low-profile alternative to a standard cage with anterior supplemental fixation. However, the mechanical stability of integrated fixation cages (IFCs) compared with a cage with anterior plate fixation under fatigue loading has not been investigated. The purpose of this study was to compare the biomechanical stability of a screw-based IFC with a standard cage coupled with that of an anterior plate under fatigue loading. METHODS Eighteen functional spinal units were implanted with either a 4-screw IFC or an anterior plate and cage (AP+C) without integrated fixation. Flexibility testing was conducted in flexion-extension (FE), lateral bending (LB), and axial rotation (AR) on intact spines, immediately after device implantation, and post-fatigue up to 20,000 cycles of FE loading. Stability parameters such as range of motion (ROM) and lax zone (LZ) for each loading mode were compared between the 2 constructs at multiple stages of testing. In addition, construct loosening was quantified by subtracting post-instrumentation ROM from post-fatigue ROM. RESULTS IFC and AP+C configurations exhibited similar stability (ROM and LZ) at every stage of testing in FE (p ≥ 0.33) and LB (p ≥ 0.23) motions. In AR, however, IFCs had decreased ROM compared with AP+C constructs at pre-fatigue (p = 0.07) and at all post-fatigue time points (p ≤ 0.05). LZ followed a trend similar to that of ROM in AR. ROM increased toward intact motion during fatigue cycling for AP+C and IFC implants. IFC specimens remained significantly (p < 0.01) more rigid than specimens in the intact condition during fatigue for each loading mode, whereas AP+C construct motion did not differ significantly (p ≥ 0.37) in FE and LB and was significantly greater (p < 0.01) in AR motion compared with intact specimens after fatigue. Weak to moderate correlations (R(2) ≤ 56%) were observed between T-scores and construct loosening, with lower T

  14. Biomechanics of Rowing

    NASA Astrophysics Data System (ADS)

    Hase, Kazunori; Kaya, Motoshi; Yamazaki, Nobutoshi; Andrews, Brian J.; Zavatsky, Amy B.; Halliday, Suzanne E.

    Compared with the other exercise, such as walking and cycling, rowing was expected to have some fitness advantage, while there were some misgivings about the risk of injury. The objectives of this study were to quantify biomechanical characteristics of rowing for fitness and rehabilitation and to offer normative data for the prevention of injury and for determining effective exercise. An experiment was performed to collect the kinematic and kinetic data during rowing by experienced and non-experienced subjects. A three-dimensional whole-body musculo-skeletal model was used to calculate the biomechanical loads, such as the joint moments, the muscular tensions, the joint contact forces and the energy consumption. The results of this study indicate that rowing is an effective exercise for rehabilitation and fitness. However, the non-experienced rower should acquire considerable skill to obtain sufficient exercise. The rowing cadence should be decided according to the purpose of the exercise.

  15. Biomechanical characteristics of bone in streptozotocin-induced diabetic rats: An in-vivo randomized controlled experimental study

    PubMed Central

    Korres, Nektarios; Tsiridis, Eleftherios; Pavlou, George; Mitsoudis, Athanasios; Perrea, Despina N; Zoumbos, Aristedes B

    2013-01-01

    AIM: To investigate the in vivo effects of type I diabetes on the mechanical strength of tibial bone in a rodent model. METHODS: The biomechanical effect of diabetes on the structural integrity of the tibia in streptozotocin induced diabetic Wistar rats was analysed. Induction of diabetes was achieved by an intra-peritoneal injection and confirmed by measuring serial blood glucose levels (> 150 mg/dL). After 8 wk the tibiae were harvested and compared to a control group. Biomechanical analysis of harvested tibiae was performed using a three-point bending technique on a servo hydraulic MTS 858 MiniBionix frame. Maximum force applied to failure (N), stiffness (N × mm) and energy absorbed (N/mm) were recorded and plotted on load displacement curves. A displacement control loading mode of 1 mm/min was selected to simulate quasi-static loading conditions. Measurements from load-displacement curves were directly compared between groups. RESULTS: Fourteen streptozotocin induced diabetic Wistar rats were compared against nineteen non-diabetic controls. An average increase of 155.2 g in body weight was observed in the control group compared with only 5 g in the diabetic group during the experimental study period. Levels of blood glucose increased to 440.25 mg/dL in the diabetic group compared to 116.62 mg/dL in the control group.The biomechanical results demonstrate a highly significant reduction in the maximum load to failure from 69.5 N to 58 N in diabetic group compared to control (P = 0.011). Energy absorption to fracture was reduced from 28.2 N in the control group to 23.5 N in the diabetic group (P = 0.082). No significant differences were observed between the groups for bending stiffness. CONCLUSION: Streptozotocin-induced diabetes in rodents reduces the maximum force and energy absorption to failure of bone, suggesting a predisposition for fracture risk. PMID:23878780

  16. Physical modelling in biomechanics.

    PubMed Central

    Koehl, M A R

    2003-01-01

    Physical models, like mathematical models, are useful tools in biomechanical research. Physical models enable investigators to explore parameter space in a way that is not possible using a comparative approach with living organisms: parameters can be varied one at a time to measure the performance consequences of each, while values and combinations not found in nature can be tested. Experiments using physical models in the laboratory or field can circumvent problems posed by uncooperative or endangered organisms. Physical models also permit some aspects of the biomechanical performance of extinct organisms to be measured. Use of properly scaled physical models allows detailed physical measurements to be made for organisms that are too small or fast to be easily studied directly. The process of physical modelling and the advantages and limitations of this approach are illustrated using examples from our research on hydrodynamic forces on sessile organisms, mechanics of hydraulic skeletons, food capture by zooplankton and odour interception by olfactory antennules. PMID:14561350

  17. Biomechanics of Rowing

    NASA Astrophysics Data System (ADS)

    Hase, Kazunori; Andrews, Brian J.; Zavatsky, Amy B.; Halliday, Suzanne E.

    A new control model for the study of biomechanical simulation of human movement was investigated using rowing as an example. The objectives were to explore biological and mechanical alternatives to optimal control methods. The simulation methods included simple control mechanisms based on proportional and derivative (PD) control, consideration of a simple neural model, introduction of an inverse dynamics system for feedback, and computational adjustment of control parameters by using an evaluative criterion and optimization method. By using simulation, appropriate rowing motions were synthesized. The generated rowing motion was periodic, continuous, and adaptable so that the pattern was stable against the mechanical force and independent of the initial condition. We believe that the simulation model is not only practical as a computational research tool from a biomechanical-engineering viewpoint but also significant from the point of view of fundamental biological theories of movement.

  18. Application Of Biomechanics Cinematography To The Study Of Sports And Industrial Injuries

    NASA Astrophysics Data System (ADS)

    Plagenhoef, Stanley

    1982-02-01

    A personal history of biomechanical analyses from motion pictures is presented. The areas of work are of total body motions of athletes in many sports, analysis of work-related injuries in industry, measurements of synthetic turfs, diagnosis of muscular imbalance, and animal motion. A film presentation illustrates each of these areas.The filming and analysing of any motion should produce data that has practical applications. This means taking measured data, interpreting it properly, and then using the information to actually obtain useful results. The practical application of data obtained from the high speed filming of humans and animals is presented here.

  19. Biomechanics of Cardiac Function

    PubMed Central

    Voorhees, Andrew P.; Han, Hai-Chao

    2015-01-01

    The heart pumps blood to maintain circulation and ensure the delivery of oxygenated blood to all the organs of the body. Mechanics play a critical role in governing and regulating heart function under both normal and pathological conditions. Biological processes and mechanical stress are coupled together in regulating myocyte function and extracellular matrix structure thus controlling heart function. Here we offer a brief introduction to the biomechanics of left ventricular function and then summarize recent progress in the study of the effects of mechanical stress on ventricular wall remodeling and cardiac function as well as the effects of wall mechanical properties on cardiac function in normal and dysfunctional hearts. Various mechanical models to determine wall stress and cardiac function in normal and diseased hearts with both systolic and diastolic dysfunction are discussed. The results of these studies have enhanced our understanding of the biomechanical mechanism in the development and remodeling of normal and dysfunctional hearts. Biomechanics provide a tool to understand the mechanism of left ventricular remodeling in diastolic and systolic dysfunction and guidance in designing and developing new treatments. PMID:26426462

  20. A Static Biomechanical Load Carriage Model

    DTIC Science & Technology

    2001-05-01

    three categories: physiological studies, biomechanical studies, and subjective appraisal studies. Most of the biomechanical studies concentrate on gait ... analysis (e.g. DeVita et al., 1991). As there are several comprehensive survey articles on various aspects of load carriage (e.g. Rorke, 1990; Haisman

  1. Dinosaur biomechanics

    PubMed Central

    Alexander, R. McNeill

    2006-01-01

    Biomechanics has made large contributions to dinosaur biology. It has enabled us to estimate both the speeds at which dinosaurs generally moved and the maximum speeds of which they may have been capable. It has told us about the range of postures they could have adopted, for locomotion and for feeding, and about the problems of blood circulation in sauropods with very long necks. It has made it possible to calculate the bite forces of predators such as Tyrannosaurus, and the stresses they imposed on its skull; and to work out the remarkable chewing mechanism of hadrosaurs. It has shown us how some dinosaurs may have produced sounds. It has enabled us to estimate the effectiveness of weapons such as the tail spines of Stegosaurus. In recent years, techniques such as computational tomography and finite element analysis, and advances in computer modelling, have brought new opportunities. Biomechanists should, however, be especially cautious in their work on animals known only as fossils. The lack of living specimens and even soft tissues oblige us to make many assumptions. It is important to be aware of the often wide ranges of uncertainty that result. PMID:16822743

  2. Dinosaur biomechanics.

    PubMed

    Alexander, R McNeill

    2006-08-07

    Biomechanics has made large contributions to dinosaur biology. It has enabled us to estimate both the speeds at which dinosaurs generally moved and the maximum speeds of which they may have been capable. It has told us about the range of postures they could have adopted, for locomotion and for feeding, and about the problems of blood circulation in sauropods with very long necks. It has made it possible to calculate the bite forces of predators such as Tyrannosaurus, and the stresses they imposed on its skull; and to work out the remarkable chewing mechanism of hadrosaurs. It has shown us how some dinosaurs may have produced sounds. It has enabled us to estimate the effectiveness of weapons such as the tail spines of Stegosaurus. In recent years, techniques such as computational tomography and finite element analysis, and advances in computer modelling, have brought new opportunities. Biomechanists should, however, be especially cautious in their work on animals known only as fossils. The lack of living specimens and even soft tissues oblige us to make many assumptions. It is important to be aware of the often wide ranges of uncertainty that result.

  3. MR LLRF VXI upgrade beam study period

    SciTech Connect

    Mesiner, K.; /Fermilab

    1995-01-01

    AD/RFI/LLRF group personnel performed several studies with the MR LLRF VXI upgrade system during the evening of 7/29/95. The study period lasted about 4 hours. The MR operating conditions were a mixture of $29 and $2B cycles, with beam injected only on the $29. The author believes the $2B cycles were present for reasons unrelated to the study. The basic study period goal was to test the initial VXI version of MR LLRF finite state machine (FSM) execution. This goal represents what has been called MR LLRF VXI Upgrade Implementation Stage No.2 throughout presentations and documentation on the upgrade project. The test includes control of MR LLRF NIM hardware, the MR RF cavities, and beam via XVI TTL FSM outputs. Numerous MR LLRF VXI system objects, or components, must work together correctly for a successful test. Very briefly, the required objects include VXI Front End hardware, the ACNET/Front End interface code, and the VXI/NIM Interface chassis (the chassis solves VXI-CAMAC-NIM RF and FSM output connectivity and development problems). Though this initial FSM does not yet fully support Upgrade Implementation Stage 2 functionality, all code and hardware for the following basic functionality is tested.

  4. Bioinspirations: cell-inspired small-scale systems for enabling studies in experimental biomechanics.

    PubMed

    Ruder, Warren C; Leduc, Philip R

    2011-07-01

    Biomechanical forces govern the behaviors of organisms and their environment and examining these behaviors to understand the underlying phenomena is an important challenge. One experimental approach for probing these interactions between organisms and their biomechanical environment uses biologically-inspired, artificial surrogates that reproduce organic mechanical systems. For the case of complex, multicellular organisms, robot surrogates have been particularly effective, such as in the analysis of the fins of fish and insects' wings. This biologically-inspired approach is also exciting when examining cell-scale responses as multicellular organisms' behavior is directly influenced by the integrated interactions of smaller-scale components (i.e., cells). In this review, we introduce the burgeoning field of engineering of artificial cells, which focuses on developing cell-scale entities replicating cellular behaviors. We describe both a bottom-up approach to constructing artificial cells, using molecular components to directly assemble artificial cells, as well as a top-down approach, in which living cells are encapsulated in a single entity whose behavior is determined by its constituent members. In particular, we discuss the potential role of these artificial cells as implantable controllers, designed to alter the mechanical behavior of a host organism. Eventually, artificial cells designed to function as small-scale controllers may help alter organisms' phenotypes.

  5. Marking-dots digital image correlation and application to studies of spinal biomechanics

    NASA Astrophysics Data System (ADS)

    Chen, Jinlong; Sun, Cuiru; Qin, Yuwen; Ji, Xinhua

    2005-04-01

    A method of marking-dots digital image correlation is developed to measure the biomechanics behavior of cattle spine. In the system, a video camera and personal computer are used to acquire digitized images of a random speckle pattern on the surface of a marking-dot before and after deformation. The method of making-dots digital image correlation can immediately measure the transformation by tracking the gray value pattern in small local neighborhoods commonly referred to as subsets. In the experiment, a specimen was selected from the cattle's spine that was covered with some muscles and tissues. It is apparent that the covering muscles and tissues cannot be treated as the information carrier, for they must be kept active and moist curing by the physiological brine in the course of the experiment. In order to solve the problem, the marking-dots were fixed into the vertebrae, and the front surface of a marking-dot was coated with a thin layer of white paint and splattered with black spot so as to create a random black-on-white speckle pattern. Experimental results have shown that the marking-dots digital image correlation method can be applied to the measurement of the biomechanical behavior of cattle spine, and offer an effective measurement tool to research the range of motion of the adjacent segment in spine under intervertebral fusion.

  6. Comparison of two tension-band fixation materials and techniques in transverse patella fractures: a biomechanical study.

    PubMed

    Rabalais, R David; Burger, Evalina; Lu, Yun; Mansour, Alfred; Baratta, Richard V

    2008-02-01

    This study compared the biomechanical properties of 2 tension-band techniques with stainless steel wire and ultra high molecular weight polyethylene (UHMWPE) cable in a patella fracture model. Transverse patella fractures were simulated in 8 cadaver knees and fixated with figure-of-8 and parallel wire configurations in combination with Kirschner wires. Identical configurations were tested with UHMWPE cable. Specimens were mounted to a testing apparatus and the quadriceps was used to extend the knees from 90 degrees to 0 degrees; 4 knees were tested under monotonic loading, and 4 knees were tested under cyclic loading. Under monotonic loading, average fracture gap was 0.50 and 0.57 mm for steel wire and UHMWPE cable, respectively, in the figure-of-8 construct compared with 0.16 and 0.04 mm, respectively, in the parallel wire construct. Under cyclic loading, average fracture gap was 1.45 and 1.66 mm for steel wire and UHMWPE cable, respectively, in the figure-of-8 construct compared with 0.45 and 0.60 mm, respectively, in the parallel wire construct. A statistically significant effect of technique was found, with the parallel wire construct performing better than the figure-of-8 construct in both loading models. There was no effect of material or interaction. In this biomechanical model, parallel wires performed better than the figure-of-8 configuration in both loading regimens, and UHMWPE cable performed similarly to 18-gauge steel wire.

  7. Emittance compensation studies of photoinjector beams with angular momentum

    SciTech Connect

    Lidia, Steven

    2003-05-19

    Beam dynamics studies on the FNPL photo injector that seek to optimize the transport of intense electron beams with large values of canonical angular momentum have been performed. These studies investigate the effect of solenoid emittance compensation on beams that evolve under the combined influence of intense space charge forces and large angular momentum. We present details of experimental measurements and supporting simulations of beam envelope evolution.

  8. Biomechanics in Schools.

    ERIC Educational Resources Information Center

    Vincent, J. F. V.

    1980-01-01

    Examines current usage of the term "biomechanics" and emphasizes the importance of differentiating between structure and material. Describes current prolects in biomechanics and lists four points about the educational significance of the field. (GS)

  9. Results of head-on beam-beam compensation studies at the Tevatron

    SciTech Connect

    Valishev, A.; Stancari, G.; /Fermilab

    2011-03-01

    At the Tevatron collider, we studied the feasibility of suppressing the antiproton head-on beam-beamtune spread using a magnetically confined 5-keV electron beam with Gaussian transverse profile overlapping with the circulating beam. When electron cooling of antiprotons is applied in regular Tevatron operations, the head-on beam-beam effect on antiprotons is small. Therefore, we first focused on the operational aspects, such as beam alignment and stability, and on fundamental observations of tune shifts, tune spreads, lifetimes, and emittances. We also attempted two special collider stores with only 3 proton bunches colliding with 3 antiproton bunches, to suppress long-range forces and enhance head-on effects. We present here the results of this study and a comparison between numerical simulations and observations, in view of the planned application of this compensation concept to RHIC.

  10. Beam-beam studies for the proposed SLAC/LBL/LLNL B Factory

    SciTech Connect

    Furman, M.A.

    1991-05-01

    We present a summary of beam-beam dynamics studies that have been carried out to date for the proposed SLAC/LBL/LLNL B Factory. Most of the material presented here is contained in the proposal's Conceptual Design Report, although post-CDR studies are also presented. 15 refs., 6 figs., 2 tabs.

  11. Studies of Ion Beam Charge Neutralization by Ferroelectric Plasma Sources

    NASA Astrophysics Data System (ADS)

    Stepanov, A.; Gilson, E. P.; Grisham, L.; Davidson, R. C.

    2013-10-01

    Space-charge forces limit the possible transverse compression of high perveance ion beams that are used in ion-beam-driven high energy density physics applications; the minimum radius to which a beam can be focused is an increasing function of perveance. The limit can be overcome if a plasma is introduced in the beam path between the focusing element and the target in order to neutralize the space charge of the beam. This concept has been implemented on the Neutralized Drift Compression eXperiment (NDCX) at LBNL using Ferroelectric Plasma Sources (FEPS). In our experiment at PPPL, we propagate a perveance-dominated ion beam through a FEPS to study the effect of the neutralizing plasma on the beam envelope and its evolution in time. A 30-60 keV space-charge-dominated Argon beam is focused with an Einzel lens into a FEPS located at the beam waist. The beam is intercepted downstream from the FEPS by a movable Faraday cup that provides time-resolved 2D current density profiles of the beam spot on target. We report results on: (a) dependence of charge neutralization on FEPS plasma density; (b) effects on beam emittance, and (c) time evolution of the beam envelope after the FEPS pulse. Research supported by the U.S. Department of Energy.

  12. Research Techniques in Biomechanics.

    ERIC Educational Resources Information Center

    Ward, Terry

    Biomechanics involves the biological human beings interacting with his/her mechanical environment. Biomechanics research is being done in connection with sport, physical education, and general motor behavior, and concerns mechanics independent of implements. Biomechanics research falls in the following two general categories: (1) that specific…

  13. Cementation of a polyethylene liner into a metal acetabular shell: a biomechanical study.

    PubMed

    Hofmann, Aaron A; Prince, Edward J; Drake, F Thurston; Hunt, Kenneth J

    2009-08-01

    Cementation of a liner into a well-fixed acetabular shell is common in revision hip arthroplasty. We compare the biomechanical strengths of cemented liners with standard locked liners. Fifty polyethylene liners were inserted into acetabular shells using the standard locking mechanism or 1 of 2 cement types then loaded to failure by torsion or lever-out testing. Lever-out testing showed that all cemented liners failed at similar loads to standard locked liners. With torsion testing, cemented liners failed at significantly higher loads than standard locked liners; roughening the liner increased load to failure. Cementation of an acetabular liner into a metal shell is safe and strong and a good alternative to metal shell replacement. Saw roughening of the polyethylene liner strengthens the poly-cement interface.

  14. Hydroxyapatite coating on PEEK implants: Biomechanical and histological study in a rabbit model.

    PubMed

    Durham, John W; Montelongo, Sergio A; Ong, Joo L; Guda, Teja; Allen, Matthew J; Rabiei, Afsaneh

    2016-11-01

    A bioactive two-layer coating consisting of hydroxyapatite (HA) and yttria-stabilized zirconia (YSZ) was investigated on cylindrical polyetheretherketone (PEEK) implants using ion beam assisted deposition (IBAD). Post-deposition heat treatments via variable frequency microwave annealing with and without subsequent autoclaving were used to crystallize the as-deposited amorphous HA layer. Microstructural analysis, performed by TEM and EDS, showed that these methods were capable of crystallizing HA coating on PEEK. The in vivo response to cylindrical PEEK samples with and without coating was studied by implanting uncoated PEEK and coated PEEK implants in the lateral femoral condyle of 18 rabbits. Animals were studied in two groups of 9 for observation at 6 or 18weeks post surgery. Micro-CT analysis, histology, and mechanical pull-out tests were performed to determine the effect of the coating on osseointegration. The heat-treated HA/YSZ coatings showed improved implant fixation as well as higher bone regeneration and bone-implant contact area compared to uncoated PEEK. The study offers a novel method to coat PEEK implants with improved osseointegration.

  15. Technology integration box beam failure study

    NASA Technical Reports Server (NTRS)

    Shuart, Mark J.; Ambur, D. R.; Davis, D. D., Jr.; Davis, Randall C.; Farley, G. L.; Lotts, C. G.; Wang, J. T.

    1992-01-01

    Composite structures have the potential to be cost effective, structurally efficient primary aircraft structures. As part of the Advanced Composite Technology (ACT) program to exploit this potential for heavily loaded aircraft structures, the design and fabrication of the technology integration box beam (TIBB) was completed. The TIBB is an advanced composite prototype structure for the center wing section of the Lockheed C-130 aircraft. The TIBB was tested for downbending, upbending, torsion, and combined upbending and torsion load conditions to verify the design. The TIBB failed at 83 percent of design ultimate load for the combined upbending and torsion load condition. Current analytical and experimental results are described for a study of the mechanisms that led to the failure of the TIBB. Experimental results include load, strain, and deflection data. An analytical study was conducted of the TIBB structural response. Analytical results include strain and deflection results from a global analysis of the TIBB.

  16. Feasibility study for mega-electron-volt electron beam tomography

    SciTech Connect

    Hampel, U.; Baertling, Y.; Hoppe, D.; Kuksanov, N.; Fadeev, S.; Salimov, R.

    2012-09-15

    Electron beam tomography is a promising imaging modality for the study of fast technical processes. But for many technical objects of interest x rays of several hundreds of keV energy are required to achieve sufficient material penetration. In this article we report on a feasibility study for fast electron beam computed tomography with a 1 MeV electron beam. The experimental setup comprises an electrostatic accelerator with beam optics, transmission target, and a single x-ray detector. We employed an inverse fan-beam tomography approach with radiographic projections being generated from the linearly moving x-ray source. Angular projections were obtained by rotating the object.

  17. TEBPP: Theoretical and Experimental study of Beam-Plasma-Physics

    NASA Technical Reports Server (NTRS)

    Anderson, H. R.; Bernstein, W.; Linson, L. M.; Papadopoulos, K.; Kellogg, P. J.; Szuszczewicz, E. P.; Hallinan, T. J.; Leinbach, H.

    1980-01-01

    The interaction of an electron beam (0 to 10 keV, 0 to 1.5 Amp) with the plasma and neutral atmospheres at 200 to 400 km altitude is studied with emphasis on applications to near Earth and cosmical plasmas. The interaction occurs in four space time regions: (1) near electron gun, beam coming into equilibrium with medium; (2) equilibrium propagation in ionosphere; (3) ahead of beam pulse, temporal and spatial precursors; (4) behind a beam pulse. While region 2 is of the greatest interest, it is essential to study Region 1 because it determines the characteristics of the beam as it enters 2 through 4.

  18. Feasibility study for mega-electron-volt electron beam tomography.

    PubMed

    Hampel, U; Bärtling, Y; Hoppe, D; Kuksanov, N; Fadeev, S; Salimov, R

    2012-09-01

    Electron beam tomography is a promising imaging modality for the study of fast technical processes. But for many technical objects of interest x rays of several hundreds of keV energy are required to achieve sufficient material penetration. In this article we report on a feasibility study for fast electron beam computed tomography with a 1 MeV electron beam. The experimental setup comprises an electrostatic accelerator with beam optics, transmission target, and a single x-ray detector. We employed an inverse fan-beam tomography approach with radiographic projections being generated from the linearly moving x-ray source. Angular projections were obtained by rotating the object.

  19. Fast beam studies of free radical photodissociation

    SciTech Connect

    Neumark, D.M.

    1993-12-01

    The authors have developed a novel technique for studying the photodissociation spectroscopy and dynamics of free radicals. In these experiments, radicals are generated by laser photodetachment of a fast (6-8 keV) mass-selected negative ion beam. The resulting radicals are photodissociated with a second laser, and the photofragments are collected and detected with high efficiency using a microchannel plate detector. The overall process is: ABC{sup -} {yields} ABC + e{sup -} {yields} A + BC, AB + C. Two types of fragment detection schemes are used. To map out the photodissociation cross-section of the radical, the photodissociation laser is scanned and the total photofragment yield is measured as a function of wavelength. In other experiments, the photodissociation frequency is fixed and the photofragment masses, kinetic energy release, and scattering angle is determined for each photodissociation event.

  20. Multiple beam antenna/switch system study

    NASA Technical Reports Server (NTRS)

    1989-01-01

    In the study of the Multiple Beam Antenna/Switch for the space to ground link (SGL) uplink and downlink services, several issues related to system engineering, antenna, transmit/receive, and switch systems were addressed and the results are provided. Bandwidth allocation at Ku band is inadequate to serve the data rate requirements for the forward and return services. Rain and depolarization effects at EHF, especially at Ka band, pose a significant threat to the link availabilities at heavy rain areas. Hardware induced effects such as the nonlinear characteristics of the power amplifier may necessitate the use of linearizers and limiters. It is also important to identify the components that are susceptible to the space radiation effects and shield or redesign them with rad-hard technologies for meeting the requirements of the space environment.

  1. Biomechanics finds practical applications in aerospace research

    NASA Astrophysics Data System (ADS)

    Yanghe, X.

    1984-10-01

    Biomechanics is a branch of science which studies the mechanical properties of biological parts using the basic principles of mechanics and engineering. Formulas and quantitative calculations are used to analyze and understand physiological phenomena. Problems caused by weightlessness, coronary heart disease, blood circulation, use of medication, and application of biomechanics in aviation rescue are discussed.

  2. Beam Dynamics Simulation Platform and Studies of Beam Breakup in Dielectric Wakefield Structures

    NASA Astrophysics Data System (ADS)

    Schoessow, P.; Kanareykin, A.; Jing, C.; Kustov, A.; Altmark, A.; Gai, W.

    2010-11-01

    A particle-Green's function beam dynamics code (BBU-3000) to study beam breakup effects is incorporated into a parallel computing framework based on the Boinc software environment, and supports both task farming on a heterogeneous cluster and local grid computing. User access to the platform is through a web browser.

  3. Beam Dynamics Simulation Platform and Studies of Beam Breakup in Dielectric Wakefield Structures

    SciTech Connect

    Schoessow, P.; Kanareykin, A.; Jing, C.; Kustov, A.; Altmark, A.; Gai, W.

    2010-11-04

    A particle-Green's function beam dynamics code (BBU-3000) to study beam breakup effects is incorporated into a parallel computing framework based on the Boinc software environment, and supports both task farming on a heterogeneous cluster and local grid computing. User access to the platform is through a web browser.

  4. Study on space charge compensation in negative hydrogen ion beam

    SciTech Connect

    Zhang, A. L.; Chen, J. E.; Peng, S. X. Ren, H. T.; Zhang, T.; Zhang, J. F.; Xu, Y.; Guo, Z. Y.

    2016-02-15

    Negative hydrogen ion beam can be compensated by the trapping of ions into the beam potential. When the beam propagates through a neutral gas, these ions arise due to gas ionization by the beam ions. However, the high neutral gas pressure may cause serious negative hydrogen ion beam loss, while low neutral gas pressure may lead to ion-ion instability and decompensation. To better understand the space charge compensation processes within a negative hydrogen beam, experimental study and numerical simulation were carried out at Peking University (PKU). The simulation code for negative hydrogen ion beam is improved from a 2D particle-in-cell-Monte Carlo collision code which has been successfully applied to H{sup +} beam compensated with Ar gas. Impacts among ions, electrons, and neutral gases in negative hydrogen beam compensation processes are carefully treated. The results of the beam simulations were compared with current and emittance measurements of an H{sup −} beam from a 2.45 GHz microwave driven H{sup −} ion source in PKU. Compensation gas was injected directly into the beam transport region to modify the space charge compensation degree. The experimental results were in good agreement with the simulation results.

  5. Further studies of shoulder and neck pain and exposures in customer service work with low biomechanical demands.

    PubMed

    Holte, Kari Anne; Westgaard, Rolf H

    2002-10-20

    The aim of the study was to establish insight into work exposures that cause shoulder and neck pain among occupational groups that have low biomechanical exposure and experience work stress from client/customer contact, among other exposures. Four occupational groups were studied, in health care (n = 20), retail (n = 22), banking (n = 26), and university secretaries (n = 26), a total of 94 volunteers. Thirty-nine were classified as pain-afflicted in the shoulder and neck, while 55 were pain-free. The subjects' perceptions of biomechanical and psychosocial exposures were established by use of quantitative questionnaires and by explorative interviews with open-ended questions, covering the same themes. Heart rate and trapezius EMG were recorded over a full workday and the following leisure period. Trapezius median and static activity during work were 3.3% and 0.3% EMG(max), only marginally higher than trapezius activity in the leisure period (2.7% and 0.2% EMG(max)). The quantitative questionnaire did not identify any variable that correlated with shoulder and neck pain except perceived general tension. The interviews established that the interaction with clients or customers was an important source of work stress. Such stress appeared to be a complex entity not easily characterized by established psychosocial questionnaires. The physiological variables were at most weakly elevated in periods with high stress as compared to periods with low stress. The authors caution against relying on standardized quantitative questionnaires and/or physiological recordings to characterize work stress in occupations with emotional stress through client/customer service work.

  6. Biomechanical Rupture Risk Assessment

    PubMed Central

    2016-01-01

    Abdominal aortic aneurysm (AAA) rupture is a local event in the aneurysm wall that naturally demands tools to assess the risk for local wall rupture. Consequently, global parameters like the maximum diameter and its expansion over time can only give very rough risk indications; therefore, they frequently fail to predict individual risk for AAA rupture. In contrast, the Biomechanical Rupture Risk Assessment (BRRA) method investigates the wall’s risk for local rupture by quantitatively integrating many known AAA rupture risk factors like female sex, large relative expansion, intraluminal thrombus-related wall weakening, and high blood pressure. The BRRA method is almost 20 years old and has progressed considerably in recent years, it can now potentially enrich the diameter indication for AAA repair. The present paper reviews the current state of the BRRA method by summarizing its key underlying concepts (i.e., geometry modeling, biomechanical simulation, and result interpretation). Specifically, the validity of the underlying model assumptions is critically disused in relation to the intended simulation objective (i.e., a clinical AAA rupture risk assessment). Next, reported clinical BRRA validation studies are summarized, and their clinical relevance is reviewed. The BRRA method is a generic, biomechanics-based approach that provides several interfaces to incorporate information from different research disciplines. As an example, the final section of this review suggests integrating growth aspects to (potentially) further improve BRRA sensitivity and specificity. Despite the fact that no prospective validation studies are reported, a significant and still growing body of validation evidence suggests integrating the BRRA method into the clinical decision-making process (i.e., enriching diameter-based decision-making in AAA patient treatment). PMID:27757402

  7. A biomechanical study on burst mechanisms of plant fruit: stress analysis of pericarps before bursting.

    PubMed

    Endo, Yasuhiro; Sakamoto, Jiro; Kashiwano, Yuki; Yokota, Hideo; Nakamura, Sakiko; Kinoshita, Eichiro

    2010-10-01

    Bursting of fruit is a very interesting biomechanical phenomenon because its mechanism is directly related to the plant's reproduction. A plant that produces fruit that bursts powerfully and spreads the seeds widely has the advantage of reproduction without relying on other mechanisms such as transportation of fruit by insects. The structures of many types of fruit have likely been optimized by evolution, although the structure itself appears rather simplistic. Strain energy is stored in each pericarp because of growth deformation, swelling or desiccation just before bursting. Throughout these changes, the mechanical stress of the pericarps is at equilibrium. At the instant of bursting, the stored strain energy is released very rapidly. Quick and wide motion of the pericarps in a certain direction is advantageous for throwing the seed a long distance. The motion and deformation of bursting pericarps depend on their tissue structure and mechanical stress condition just before the burst. We tracked the bursting motion by using a high-speed camera. Then we calculated the pre-burst stress generated in a pericarp of Impatiens by using the finite-element method. The boundary condition obtained by experiments using a high-speed video camera is given, and the stress was calculated using reverse deformation analysis. The stress distribution of the pericarp is effective in causing the pericarp motion to throw the seeds far away.

  8. Effects of the fibers distribution in the human eardrum: A biomechanical study.

    PubMed

    Gentil, Fernanda; Parente, Marco; Martins, Pedro; Garbe, Carolina; Santos, Carla; Areias, Bruno; Branco, Carla; Paço, João; Jorge, Renato Natal

    2016-06-14

    The eardrum separates the external ear from the middle ear and it is responsible to convert the acoustical energy into mechanical energy. It is divided by pars tensa and pars flaccida. The aim of this work is to analyze the susceptibility of the four quadrants of the pars tensa under negative pressure, to different lamina propria fibers distribution. The development of associated ear pathology, in particular the formation of retraction pockets, is also evaluated. To analyze these effects, a computational biomechanical model of the tympano-ossicular chain was constructed using computerized tomography images and based on the finite element method. Three fibers distributions in the eardrum middle layer were compared: case 1 (eardrum with a circular band of fibers surrounding all quadrants equally), case 2 (eardrum with a circular band of fibers that decreases in thickness in posterior quadrants), case 3 (eardrum without circular fibers in the posterior/superior quadrant). A static analysis was performed by applying approximately 3000Pa in the eardrum. The pars tensa of the eardrum was divided in four quadrants and the displacement of a central point of each quadrant analyzed. The largest displacements of the eardrum were obtained for the eardrum without circular fibers in the posterior/superior quadrant.

  9. Biomechanical studies in an ovine model of non-accidental head injury.

    PubMed

    Anderson, R W G; Sandoz, B; Dutschke, J K; Finnie, J W; Turner, R J; Blumbergs, P C; Manavis, J; Vink, R

    2014-08-22

    This paper presents the head kinematics of a novel ovine model of non-accidental head injury (NAHI) that consists only of a naturalistic oscillating insult. Nine, 7-to-10-day-old anesthetized and ventilated lambs were subjected to manual shaking. Two six-axis motion sensors tracked the position of the head and torso, and a triaxial accelerometer measured head acceleration. Animals experienced 10 episodes of shaking over 30 min, and then remained under anesthesia for 6h until killed by perfusion fixation of the brain. Each shaking episode lasted for 20s resulting in about 40 cycles per episode. Each cycle typically consisted of three impulsive events that corresponded to specific phases of the head's motion; the most substantial of these were interactions typically with the lamb's own torso, and these generated accelerations of 30-70 g. Impulsive loading was not considered severe. Other kinematic parameters recorded included estimates of head power transfer, head-torso flexion, and rate of flexion. Several styles of shaking were also identified across episodes and subjects. Axonal injury, neuronal reaction and albumin extravasation were widely distributed in the hemispheric white matter, brainstem and at the craniocervical junction and to a much greater magnitude in lower body weight lambs that died. This is the first biomechanical description of a large animal model of NAHI in which repetitive naturalistic insults were applied, and that reproduced a spectrum of injury associated with NAHI.

  10. Classroom Journal Club: Collaborative Study of Contemporary Primary Literature in the Biomechanics Classroom.

    PubMed

    Kuxhaus, Laurel; Corbiere, Nicole C

    2016-07-01

    Current engineering pedagogy primarily focuses on developing technical proficiency and problem solving skills; the peer-review process for sharing new research results is often overlooked. The use of a collaborative classroom journal club can engage students with the excitement of scientific discovery and the process of dissemination of research results, which are also important lifelong learning skills. In this work, a classroom journal club was implemented and a survey of student perceptions spanning three student cohorts was collected. In this collaborative learning activity, students regularly chose and discussed a recent biomechanics journal article, and were assessed based on specific, individual preparation tasks. Most student-chosen journal articles were relevant to topics discussed in the regular class lecture. Surveys assessed student perceptions of the activity. The survey responses show that, across all cohorts, students both enjoyed the classroom journal club and recognized it as an important learning experience. Many reported discussing their journal articles with others outside of the classroom, indicating good engagement. The results demonstrate that student engagement with primary literature can foster both technical knowledge and lifelong learning skills.

  11. Parametric study of transport beam lines for electron beams accelerated by laser-plasma interaction

    NASA Astrophysics Data System (ADS)

    Scisciò, M.; Lancia, L.; Migliorati, M.; Mostacci, A.; Palumbo, L.; Papaphilippou, Y.; Antici, P.

    2016-03-01

    In the last decade, laser-plasma acceleration of high-energy electrons has attracted strong attention in different fields. Electrons with maximum energies in the GeV range can be laser-accelerated within a few cm using multi-hundreds terawatt (TW) lasers, yielding to very high beam currents at the source (electron bunches with up to tens-hundreds of pC in a few fs). While initially the challenge was to increase the maximum achievable electron energy, today strong effort is put in the control and usability of these laser-generated beams that still lack of some features in order to be used for applications where currently conventional, radio-frequency (RF) based, electron beam lines represent the most common and efficient solution. Several improvements have been suggested for this purpose, some of them acting directly on the plasma source, some using beam shaping tools located downstream. Concerning the latter, several studies have suggested the use of conventional accelerator magnetic devices (such as quadrupoles and solenoids) as an easy implementable solution when the laser-plasma accelerated beam requires optimization. In this paper, we report on a parametric study related to the transport of electron beams accelerated by laser-plasma interaction, using conventional accelerator elements and tools. We focus on both, high energy electron beams in the GeV range, as produced on petawatt (PW) class laser systems, and on lower energy electron beams in the hundreds of MeV range, as nowadays routinely obtained on commercially available multi-hundred TW laser systems. For both scenarios, our study allows understanding what are the crucial parameters that enable laser-plasma accelerators to compete with conventional ones and allow for a beam transport. We show that suitable working points require a tradeoff-combination between low beam divergence and narrow energy spread.

  12. Technology integration box beam failure study

    NASA Technical Reports Server (NTRS)

    Shuart, Mark J.; Ambur, Damodar R.; Davis, D. D., Jr.; Davis, R. C.; Farley, G. L.; Lotts, C. G.; Wang, J. T.

    1992-01-01

    The objective of this paper is to describe current results from an on-going study of the mechanisms that led to the failure of the TIBB. Experimental and analytical results are presented. Experimental results include load, strain, and deflection data for the TIBB (Technology Integration Box Beam). An analytical investigation was conducted to compliment the experimental investigation and to gain additional insight into the TIBB structural response. Analytical results include strain and deflection results from a global analysis of the TIBB. A local analysis of the failure region is being completed. These analytical results are validated through comparisons with the experimental results from the TIBB tests. The experimental and analytical results from the TIBB tests are used to determine a sequence of events that may have resulted in failure of the TIBB. A potential cause of failure is high stresses in a stiffener runout region. Typical analytical results are presented for a stiffener runout specimen that is being defined to simulate the TIBB failure mechanisms. The results of this study are anticipated to provide better understanding of potential failure mechanisms in composite aircraft structures, to lead to future design improvements, and to identify needed analytical tools for design and analysis.

  13. Recent study of beam stability in the PSR

    SciTech Connect

    Wang, T.S.F.; Cooper, R.; Fitzgerald, D.; Frankle, S.; Hardek, T.; Hutson, R.; Macek, R.; Ohmori, C.; Plum, M.; Thiessen, H.; Wilkinson, C. ); Colton, E. ); Neuffer, D. ); Rees, G. )

    1993-01-01

    A fast transverse instability with beam loss has been observed in the 800 MeV Los Alamos Pro Ring (PSR) when the injected beam intensity reaches 2 - 4 [times] 10[sup 13] protons per pulse. Previous observations in that the instability is most likely driven by electrons trapped within the proton beam. Theoretical study shown that beam leakage into the inter-bunch gap leads to electron trapping. Recent experiments were carried out by using the newly implemented pinger'' and by varying the machine transition gamma to explore further the e-p'' instability and the nature of the instability. This paper summarizes some of these recent experimental results and theoretical studies.

  14. Recent study of beam stability in the PSR

    SciTech Connect

    Wang, T.S.F.; Cooper, R.; Fitzgerald, D.; Frankle, S.; Hardek, T.; Hutson, R.; Macek, R.; Ohmori, C.; Plum, M.; Thiessen, H.; Wilkinson, C.; Colton, E.; Neuffer, D.; Rees, G.

    1993-06-01

    A fast transverse instability with beam loss has been observed in the 800 MeV Los Alamos Pro Ring (PSR) when the injected beam intensity reaches 2 - 4 {times} 10{sup 13} protons per pulse. Previous observations in that the instability is most likely driven by electrons trapped within the proton beam. Theoretical study shown that beam leakage into the inter-bunch gap leads to electron trapping. Recent experiments were carried out by using the newly implemented ``pinger`` and by varying the machine transition gamma to explore further the ``e-p`` instability and the nature of the instability. This paper summarizes some of these recent experimental results and theoretical studies.

  15. Molecular beam studies of reaction dynamics

    SciTech Connect

    Lee, Y.T.

    1993-12-01

    The major thrust of this research project is to elucidate detailed dynamics of simple elementary reactions that are theoretically important and to unravel the mechanism of complex chemical reactions or photochemical processes that play important roles in many macroscopic processes. Molecular beams of reactants are used to study individual reactive encounters between molecules or to monitor photodissociation events in a collision-free environment. Most of the information is derived from measurement of the product fragment energy, angular, and state distributions. Recent activities are centered on the mechanisms of elementary chemical reactions involving oxygen atoms with unsaturated hydrocarbons, the dynamics of endothermic substitution reactions, the dependence of the chemical reactivity of electronically excited atoms on the alignment of excited orbitals, the primary photochemical processes of polyatomic molecules, intramolecular energy transfer of chemically activated and locally excited molecules, the energetics of free radicals that are important to combustion processes, the infrared-absorption spectra of carbonium ions and hydrated hydronium ions, and bond-selective photodissociation through electric excitation.

  16. Molecular beam studies of reaction dynamics

    SciTech Connect

    Lee, Yuan T.

    1991-03-01

    The major thrust of this research project is to elucidate detailed dynamics of simple elementary reactions that are theoretically important and to unravel the mechanism of complex chemical reactions or photochemical processes that play important roles in many macroscopic processes. Molecular beams of reactants are used to study individual reactive encounters between molecules or to monitor photodissociation events in a collision-free environment. Most of the information is derived from measurement of the product fragment energy, angular, and state distributions. Recent activities are centered on the mechanisms of elementary chemical reactions involving oxygen atoms with unsaturated hydrocarbons, the dynamics of endothermic substitution reactions, the dependence of the chemical reactivity of electronically excited atoms on the alignment of excited orbitals, the primary photochemical processes of polyatomic molecules, intramolecular energy transfer of chemically activated and locally excited molecules, the energetics of free radicals that are important to combustion processes, the infrared-absorption spectra of carbonium ions and hydrated hydronium ions, and bond-selective photodissociation through electric excitation.

  17. Technology integration box beam failure study

    NASA Technical Reports Server (NTRS)

    Shuart, M. J.; Ambur, Damodar R.; Davis, D. D., Jr.; Davis, R. C.; Farley, G. L.; Lotts, C. G.; Wang, J. T.

    1993-01-01

    Composite structures have the potential to be cost-effective, structurally efficient primary aircraft structures. The Advanced Composites Technology (ACT) Program has the goal to develop the technology to exploit this potential for heavily loaded aircraft structures. As part of the ACT Program, Lockheed Aeronautical Systems Company completed the design and fabrication of the Technology Integration Box Beam (TIBB). The TIBB is an advanced composite prototype structure for the center wing section of the C-130 aircraft. Lockheed subjected the TIBB to downbending, upbending, torsion and combined upbending and torsion load conditions to verify the design. The TIBB failed at 83 percent of design ultimate load for the combined upbending and torsion load condition. The objective of this paper is to describe the mechanisms that led to the failure of the TIBB. The results of a comprehensive analytical and experimental study are presented. Analytical results include strain and deflection results from both a global analysis of the TIBB and a local analysis of the failure region. These analytical results are validated by experimental results from the TIBB tests. The analytical and experimental results from the TIBB tests are used to determine a sequence of events that resulted in failure of the TIBB. A potential cause of failure is high stresses in a stiffener runout region. Analytical and experimental results are also presented for a stiffener runout specimen that was used to simulate the TIBB failure mechanisms.

  18. Patellofemoral anatomy and biomechanics.

    PubMed

    Sherman, Seth L; Plackis, Andreas C; Nuelle, Clayton W

    2014-07-01

    Patellofemoral disorders are common. There is a broad spectrum of disease, ranging from patellofemoral pain and instability to focal cartilage disease and arthritis. Regardless of the specific condition, abnormal anatomy and biomechanics are often the root cause of patellofemoral dysfunction. A thorough understanding of normal patellofemoral anatomy and biomechanics is critical for the treating physician. Recognizing and addressing abnormal anatomy will optimize patellofemoral biomechanics and may ultimately translate into clinical success.

  19. A feasibility study of multiplexing parallel beam.

    PubMed

    Ma, Jiayi; Zhao, Jingwu; Shi, Xiaodong; Huang, Runshen

    2013-05-01

    Single-photon emission computed tomography (SPECT) is a suitable tool for clinically localizing deep-sited tumors; SPECT with high spatial resolution has the ability to localize deep-sited tumors precisely. However, because of its poor sensitivity, in China SPECT now only plays a complementary role. To improve the sensitivity of the parallel beam collimator mainly used in China, a multiplexing parallel beam collimator is proposed, which can improve sensitivity while maintaining higher spatial resolution by using theoretical prediction and Monte Carlo simulation. The improved sensitivity-to-spatial resolution ratio has an optimal value. In addition, a set of gamma ray channels, introduced only in the transverse direction, did not have any effect in the axial direction. In the transverse direction, the projection data are the sum of the parallel beam and two oblique parallel beams. From visual assessment obtained using computer simulations with equal sensitivity, the reconstructed image at deep-sited was noticeably better than that with the high sensitivity parallel beam.

  20. Simulation Studies of Beam-Beam Effects of a Ring-Ring Electron-Ion Collider Based on CEBAF

    SciTech Connect

    Yuhong Zhang,Ji Qiang

    2009-05-01

    The collective beam-beam effect can potentially cause a rapid growth of beam sizes and reduce the luminosity of a collider to an unacceptably low level. The ELIC, a proposed ultra high luminosity electron-ion collider based on CEBAF, employs high repetition rate crab crossing colliding beams with very small bunch transverse sizes and very short bunch lengths, and collides them at up to 4 interaction points with strong final focusing. All of these features can make the beam-beam effect challenging. In this paper, we present simulation studies of the beam-beam effect in ELIC using a self-consistent strong-strong beam-beam simulation code developed at Lawrence Berkeley National Laboratory. This simulation study is used for validating the ELIC design and for searching for an optimal parameter set.

  1. Numerical study of neutron beam divergence in a beam-fusion scenario employing laser driven ions

    NASA Astrophysics Data System (ADS)

    Alejo, A.; Green, A.; Ahmed, H.; Robinson, A. P. L.; Cerchez, M.; Clarke, R.; Doria, D.; Dorkings, S.; Fernandez, J.; McKenna, P.; Mirfayzi, S. R.; Naughton, K.; Neely, D.; Norreys, P.; Peth, C.; Powell, H.; Ruiz, J. A.; Swain, J.; Willi, O.; Borghesi, M.; Kar, S.

    2016-09-01

    The most established route to create a laser-based neutron source is by employing laser accelerated, low atomic-number ions in fusion reactions. In addition to the high reaction cross-sections at moderate energies of the projectile ions, the anisotropy in neutron emission is another important feature of beam-fusion reactions. Using a simple numerical model based on neutron generation in a pitcher-catcher scenario, anisotropy in neutron emission was studied for the deuterium-deuterium fusion reaction. Simulation results are consistent with the narrow-divergence (∼ 70 ° full width at half maximum) neutron beam recently served in an experiment employing multi-MeV deuteron beams of narrow divergence (up to 30° FWHM, depending on the ion energy) accelerated by a sub-petawatt laser pulse from thin deuterated plastic foils via the Target Normal Sheath Acceleration mechanism. By varying the input ion beam parameters, simulations show that a further improvement in the neutron beam directionality (i.e. reduction in the beam divergence) can be obtained by increasing the projectile ion beam temperature and cut-off energy, as expected from interactions employing higher power lasers at upcoming facilities.

  2. Biomechanics in dermatology: Recent advances and future directions.

    PubMed

    Lewinson, Ryan T; Haber, Richard M

    2017-02-01

    Biomechanics is increasingly being recognized as an important research area in dermatology. To highlight only a few examples, biomechanics has contributed to the development of novel topical therapies for aesthetic and medical purposes, enhanced our understanding of the pathogenesis of plantar melanoma, and provided insight into the epidemiology of psoriatic disease. This article summarizes the findings from recent studies to demonstrate the important role that biomechanics may have in dermatologic disease and therapy and places these biomechanical findings in a clinical context for the practicing physician. In addition, areas for future biomechanics research and development in dermatology are discussed.

  3. Biomechanical strain of goldsmiths.

    PubMed

    Cândido, Paula Emanuela Fernandes; Teixeira, Juliana Vieira Schmidt; Moro, Antônio Renato Pereira; Gontijo, Leila Amaral

    2012-01-01

    The work of the goldsmiths consists in the manufacture of jewelry. The piece, be it an earring, bracelet or necklace, is hand-assembled. This task requires precision, skill, kindness and patience. In this work, we make use of tools such as cuticle clippers and rounded tip, beads or precious stones and also pieces of metal. This type of activity requires a biomechanical stress of hands and wrists. In order to quantify the biomechanical stress, we performed a case study to measure the movements performed by an assembly of pieces of jewelry. As method for research, filming was done during assembly of parts to a paste, using a Nikon digital camera, for 1 (one) hour. The film was edited by Kinovea software, and the task was divided into cycles, each cycle corresponds to a complete object. In one cycle, there are four two movements of supination and pronation movements of the forearm. The cycle lasts approximately sixteen seconds, totaling 1800 cycles in eight hours. Despite the effort required of the wrists, the activity shows no complaints from the employees, but this fact does not mischaracterizes the ability of employees to acquire repetitive strain injuries and work-related musculoskeletal disorders.

  4. ATOMIC BEAM STUDIES IN THE RHIC H-JET POLARIMETER.

    SciTech Connect

    MAKDISI,Y.; ZELENSKI,A.; GRAHAM,D.; KOKHANOVSKI,S.; MAHLER,G.; NASS,A.; RITTER,J.; ZUBETS,V.; ET AL.

    2005-01-28

    The results of atomic beam production studies are presented. Improved cooling of the atoms before jet formation in the dissociator cold nozzle apparently reduces the atomic beam velocity spread and improves beam focusing conditions. A carefully designed sextupole separating (and focusing) magnet system takes advantage of the high brightness source. As a result a record beam intensity of a 12.4 {center_dot} 10{sup 16} atoms/s was obtained within 10 mm acceptance at the collision point. The results of the polarization dilution factor measurements (by the hydrogen molecules at the collision point) are also presented.

  5. Experimental Studies of Ion Beam Neutralization: Preliminary Results

    SciTech Connect

    Ding, N.; Polansky, J.; Downey, R.; Wang, J.

    2011-05-20

    A testing platform is designed to study ion beam neutralization in the mesothermal, collisionless region. In the experimental setup, argon neutrals were ionized in a microwave cavity and accelerated by a plasma lens system which was biased to 2500 V above the system ground. Electrons were boiled off from two hot tungsten filaments to neutralize the ion beam. The plasma is diagnosed using Langmuir probe and Faraday probe. A 3-D traversing system and a complete data acquisition loop were developed to efficiently measure 3-D beam profile. Preliminary measurements of beam profiles are presented for different operating conditions.

  6. Anatomy and Biomechanical Properties of the Plantar Aponeurosis: A Cadaveric Study

    PubMed Central

    Chen, Da-wei; Li, Bing; Aubeeluck, Ashwin; Yang, Yun-feng; Huang, Yi-gang; Zhou, Jia-qian; Yu, Guang-rong

    2014-01-01

    Objectives To explore the anatomy of the plantar aponeurosis (PA) and its biomechanical effects on the first metatarsophalangeal (MTP) joint and foot arch. Methods Anatomic parameters (length, width and thickness of each central PA bundle and the main body of the central part) were measured in 8 cadaveric specimens. The ratios of the length and width of each bundle to the length and width of the central part were used to describe these bundles. Six cadaveric specimens were used to measure the range of motion of the first MTP joint before and after releasing the first bundle of the PA. Another 6 specimens were used to evaluate simulated static weight-bearing. Changes in foot arch height and plantar pressure were measured before and after dividing the first bundle. Results The average width and thickness of the origin of the central part at the calcaneal tubercle were 15.45 mm and 2.79 mm respectively. The ratio of the length of each bundle to the length of the central part was (from medial to lateral) 0.29, 0.30, 0.28, 0.25, and 0.27, respectively. Similarly, the ratio of the widths was 0.26, 0.25, 0.23, 0.19 and 0.17. The thickness of each bundle at the bifurcation of the PA into bundles was (from medial to lateral) 1.26 mm, 1.04 mm, 0.91 mm, 0.84 mm and 0.72 mm. The average dorsiflexion of the first MTP joint increased 10.16° after the first bundle was divided. Marked acute changes in the foot arch height and the plantar pressure were not observed after division. Conclusions The first PA bundle was not the longest, widest, or the thickest bundle. Releasing the first bundle increased the range of motion of the first MTP joint, but did not acutely change foot arch height or plantar pressure during static load testing. PMID:24392127

  7. Alignment Sensitivity Study of the St. ANA Beam Line

    NASA Astrophysics Data System (ADS)

    Gervais, Michelle; Couder, Manoel; Jung, Hyo Soon; Setoodehnia, Kiana

    2014-09-01

    The St. ANA (STable Accelerator for Nuclear Astrophysics) accelerator is being prepared for use with the St. George recoil mass separator. The accelerator is in working condition for use in direct kinematic experiments but the St. George separator works with inverse kinematics and requires a highly controlled beam restricted by severe position and divergence parameters that are not achieved at the present time. A systematic sensitivity study was conducted using a simulation of the beam line in order to assess the impact of a misalignment in each optical element or in the beam itself. Tests were done with the beam to analyze how the beam behaves at various points in the line and to compare this data with simulation results to determine possible causes of misalignment. The results of these tests and simulations are that the beam characteristics are now better understood and the possible causes of the limitations have been narrowed down. The St. ANA (STable Accelerator for Nuclear Astrophysics) accelerator is being prepared for use with the St. George recoil mass separator. The accelerator is in working condition for use in direct kinematic experiments but the St. George separator works with inverse kinematics and requires a highly controlled beam restricted by severe position and divergence parameters that are not achieved at the present time. A systematic sensitivity study was conducted using a simulation of the beam line in order to assess the impact of a misalignment in each optical element or in the beam itself. Tests were done with the beam to analyze how the beam behaves at various points in the line and to compare this data with simulation results to determine possible causes of misalignment. The results of these tests and simulations are that the beam characteristics are now better understood and the possible causes of the limitations have been narrowed down. Project advisor

  8. H line; a beam line for fundamental physics study

    NASA Astrophysics Data System (ADS)

    Kawamura, Naritoshi; Toyoda, Akihisa; Aoki, Masaharu; Shimomura, Koichiro; Mibe, Tsutomu; Nakatsugawa, Yohei; Otani, Masashi; Saito, Naohito; Miyake, Yasuhiro

    2014-12-01

    The muon facility, J-PARC (Muon Science Establishment; MUSE), has been operating since the first beam in 2008. Starting with a 200 kW proton beam, a beam intensity of 3 × 106 muons/s was reached in 2009 which was the most intense pulsed muon beam in the world. From the 2 cm thick graphite target, four secondary muon beam lines are designed to be extracted. Three beam lines currently exist, the first being operational and the other two undergoing commissioning. The fourth and the last beam line, the H line, is planned to be constructed. This new beam line is designed to have a large acceptance, provides the ability to tune the momentum, and use a kicker magnet and/or a Wien filter. The H line is designed to provide an intense beam of 108 surface muons/s for fundamental physics studies to observe new physics beyond the standard model. Such studies require high statistics and they need to occupy the experimental areas for a relatively long period.

  9. Influences of tongue biomechanics on speech movements during the production of velar stop consonants: A modeling study

    NASA Astrophysics Data System (ADS)

    Perrier, Pascal; Payan, Yohan; Zandipour, Majid; Perkell, Joseph

    2003-09-01

    This study explores the following hypothesis: forward looping movements of the tongue that are observed in VCV sequences are due partly to the anatomical arrangement of the tongue muscles, how they are used to produce a velar closure, and how the tongue interacts with the palate during consonantal closure. The study uses an anatomically based two-dimensional biomechanical tongue model. Tissue elastic properties are accounted for in finite-element modeling, and movement is controlled by constant-rate control parameter shifts. Tongue raising and lowering movements are produced by the model mainly with the combined actions of the genioglossus, styloglossus, and hyoglossus. Simulations of V1CV2 movements were made, where C is a velar consonant and V is [a], [i], or [u]. Both vowels and consonants are specified in terms of targets, but for the consonant the target is virtual, and cannot be reached because it is beyond the surface of the palate. If V1 is the vowel [a] or [u], the resulting trajectory describes a movement that begins to loop forward before consonant closure and continues to slide along the palate during the closure. This pattern is very stable when moderate changes are made to the specification of the target consonant location and agrees with data published in the literature. If V1 is the vowel [i], looping patterns are also observed, but their orientation was quite sensitive to small changes in the location of the consonant target. These findings also agree with patterns of variability observed in measurements from human speakers, but they contradict data published by Houde [Ph.D. dissertation (1967)]. These observations support the idea that the biomechanical properties of the tongue could be the main factor responsible for the forward loops when V1 is a back vowel, regardless of whether V2 is a back vowel or a front vowel. In the [i] context it seems that additional factors have to be taken into consideration in order to explain the observations made

  10. Beam Dynamics Studies for the SPARC Project

    SciTech Connect

    Ferrario, M.; Biagini, Maria E.; Boscolo, M.; Fusco, V.; Guiducci, S.; Migliorati, M.; Serafini, L.; Vaccarezza, C.; Bartolini, R.; Giannessi, L.; Quattromini, M.; Ronsivalle, C.; Limborg, C.G.; /Unlisted /Unlisted /ENEA, Frascati /SLAC

    2008-03-17

    The aim of the SPARC project, is to promote an R&D activity oriented to the development of a high brightness photoinjector to drive SASE-FEL experiments. We discuss in this paper the status of the beam dynamics simulation activities.

  11. Atom beam surface interaction studies: Experimental system development

    NASA Technical Reports Server (NTRS)

    Gregory, J. C.

    1973-01-01

    Quantitative deposition by standard techniques of adsorbates containing C and Si onto selected substrates is studied. The interaction kinetics of a beam of oxygen, nitrogen, or hydrogen atoms of known flux are investigated by Auger electron spectroscopy and LEED. Desborbed molecules will be analyzed by mass spectroscopy using modulated beam techniques. Experimental conditions permitting, two sets of measurements will be correlated.

  12. Biomechanical evaluation of reconstruction plates with locking, nonlocking, and hybrid screws configurations in calcaneal fracture: a finite element model study.

    PubMed

    Chen, Ching-Hsuan; Hung, Chinghua; Hsu, Yu-Chun; Chen, Chen-Sheng; Chiang, Chao-Ching

    2017-02-21

    Calcaneal fractures are the most common fractures of the tarsal bones. The stability of fixation is an important factor for successful reconstruction of calcaneal fractures. The purpose of this study was to analyze the biomechanical influence of plate fixation with different combinations of locking and nonlocking screws during early weight-bearing phase. A three-dimensional FE foot model was established using ANSYS software, which comprised bones, cartilages, plantar fascia, and soft tissue. Calcaneal plate was fixed with whole locking (WLS), whole nonlocking (WNS), and hybrid screw configurations for FE analysis. The WNS generated a 6.1° and 2.2° Bohler angle decrease compared with the intact model and WLS (WNS: 18.9; WLS: 21.1; intact: 25.0°). Some hybrid screw configurations (Bohler angle: 21.5° and 21.2°) generated stability similar to WLS. The FE results showed that the fragments at the posterior facet and the posterior tuberosity sustained more stress. This study recommends that the hybrid screw configuration with at least four locking screws, two at the posterior facet fragment and two at the posterior tuberosity fragment, is the optimal choice for the fixation of Sanders type IIB calcaneal fractures.

  13. [A biomechanical study of the mechanical stress transmission of dental implants using finite element analysis. Review of literature. Part I].

    PubMed

    Szucs, Attila; Divinyi, Tamás; Lorincz, Adám

    2006-08-01

    Finite Element Analysis (FEA) is a computerised investigative method that is capable of determining the mechanical stress arising in various objects and their environment as a result of forces effecting the system by using a mathematical model. The method is most often used for purposes of technical, engineering design, but is very useful for medical purposes-the static and functional investigation of the skeletal and motor system of the human body-as well. The transmission of mechanical stress between the implant and bone depends on a number of factors, and its description is quite complicated. A model has to be created to perform a FEA, the geometric data of the implant, the mechanical properties of the bone and the parameters of the bone-implant interface have to be determined, a so-called finite element network has to be created. Valuable data can be obtained by changing the individual elements of the system. The study of dental implants makes it possible to better investigate biomechanical conditions and thus the further perfection of implant methods. In the first part of the present two-part publication authors review the possibilities of use of the finite element analysis in examining the stress transmission of dental implants. In the second part of the publication their own studies will be presented.

  14. The morphological and biomechanical changes of keratocytes cultured on modified p (HEMA-MMA) hydrogel studied by AFM.

    PubMed

    Yan, Tuo; Sun, Rong; Deng, Hua; Tan, Baihua; Ao, Ningjian

    2009-01-01

    The poor integration with host cornea tissue and the low mechanical properties of pHEMA hydrogel for artificial cornea remains a difficult problem to solve. A modified pHEMA hydrogel, MMA copolymerized and type-I collagen and bFGF immobilized, was previously prepared in an attempt to solve the problems. In this study, the cytotoxicity of Col/bFGF-p (HEMA-MMA) and p (HEMA-MMA) was studied by cell adhesion assay and atomic force microscopy (AFM). The results of cell adhesion assay show that the attachment of keratocytes on the modified membrane is much higher than that of the unmodified membrane. This indicates that the material after modification have better cell-material interaction. The AFM images reveal that the morphology of keratocytes cultured on different substrate is obviously different. The cell cultured on modified membrane presented a completely elongated and spindle-shape morphology. The force-distance indicates that the biomechanical of keratocytes changes significantly after culturing on different substrates. The adhesion force (2328+/-523 pN) and Young's modulus (0.51+/-0.125 kPa) of the cell cultured on modified membrane are much higher, and the stiffness (0.08+/-0.022 mN/m) is lower than those of the cell cultured on unmodified membrane. These results show that the cytotoxicity of Col/bFGF-p (HEMA-MMA) for keratocytes is much improved.

  15. [Biomechanics and aging].

    PubMed

    Struck, H J

    1991-01-01

    Starting from the physical basics of the biomechanics of connective tissues, organ structures and the corresponding age-related changes of skin, tendons, ligaments, cartilage, bones, blood vessels, and lungs are described. Finally, exogenous factors such as nutrition, hormones, immobilization, activity and adaptive mechanisms and their influence on the biomechanical properties of connective tissue are represented.

  16. Reduction of Biomechanical and Welding Fume Exposures in Stud Welding.

    PubMed

    Fethke, Nathan B; Peters, Thomas M; Leonard, Stephanie; Metwali, Mahmoud; Mudunkotuwa, Imali A

    2016-04-01

    The welding of shear stud connectors to structural steel in construction requires a prolonged stooped posture that exposes ironworkers to biomechanical and welding fume hazards. In this study, biomechanical and welding fume exposures during stud welding using conventional methods were compared to exposures associated with use of a prototype system that allowed participants to weld from an upright position. The effect of base material (i.e. bare structural beam versus galvanized decking) on welding fume concentration (particle number and mass), particle size distribution, and particle composition was also explored. Thirty participants completed a series of stud welding simulations in a local apprenticeship training facility. Use of the upright system was associated with substantial reductions in trunk inclination and the activity levels of several muscle groups. Inhalable mass concentrations of welding fume (averaged over ~18 min) when using conventional methods were high (18.2 mg m(-3) for bare beam; 65.7 mg m(-3) for through deck), with estimated mass concentrations of iron (7.8 mg m(-3) for bare beam; 15.8 mg m(-3) for through deck), zinc (0.2 mg m(-3) for bare beam; 15.8 mg m(-3) for through deck), and manganese (0.9 mg m(-3) for bare beam; 1.5 mg m(-3) for through deck) often exceeding the American Conference of Governmental Industrial Hygienists Threshold Limit Values (TLVs). Number and mass concentrations were substantially reduced when using the upright system, although the total inhalable mass concentration remained above the TLV when welding through decking. The average diameters of the welding fume particles for both bare beam (31±17 nm) through deck conditions (34±34 nm) and the chemical composition of the particles indicated the presence of metallic nanoparticles. Stud welding exposes ironworkers to potentially high levels of biomechanical loading (primarily to the low back) and welding fume. The upright system used in this study improved exposure

  17. Long-range and head-on beam-beam compensation studies in RHIC with lessons for the LHC

    SciTech Connect

    Fischer,W.; Luo, Y.; Abreu, N.; Calaga, R.; Montag, C.; Robert-Demolaize, G.; Dorda, U.; Koutchouk, J. -P.; Sterbini, G.; Zimmermann, F.; Kim, H. -J.; Sen, T.; Shiltsev, V.; Valishev, A.; Qiang, J.; Kabel, A.

    2008-11-24

    Long-range as well as head-on beam-beam effects are expected to limit the LHC performance with design parameters. They are also important consideration for the LHC upgrades. To mitigate long-range effects current carrying wires parallel to the beam were proposed. Two such wires are installed in RHIC where they allow studying the effect of strong long-range beam-beam effects, as well as the compensation of a single long-range interaction. The tests provide benchmark data for simulations and analytical treatments. To reduce the head-on beam-beam effect electron lenses were proposed for both RIDC and the LHC. We present the experimental long-range beam-beam program at RHIC and report on head-on compensations studies based on simulations.

  18. Long-Range And Head-On Beam-Beam Compensation Studies in RHIC With Lessons for the LHC

    SciTech Connect

    Fischer, W.; Luo, Y.; Abreu, N.; Calaga, R.; Montag, C.; Robert-Demolaize, G.; Dorda, U.; Koutchouk, J.P.; Sterbini, G.; Zimmermann, F.; Kim, H.J.; Sen, T.; Shiltsev, V.; Valishev, A.; Qiang, J.; Kabel, A.; /SLAC

    2011-11-28

    Long-range as well as head-on beam-beam effects are expected to limit the LHC performance with design parameters. They are are also important consideration for the LHC upgrades. To mitigate long-range effects, current carrying wires parallel to the beam were proposed. Two such wires are installed in RHIC where they allow studying the effect of strong long-range beam-beam effects, as well as the compensation of a single long-range interaction. The tests provide benchmark data for simulations and analytical treatments. Electron lenses were proposed for both RHIC and the LHC to reduce the head-on beam-beam effect. We present the experimental long-range beam-beam program at RHIC and report on head-on compensations studies based on simulations.

  19. Long-range and head-on beam-beam compensation studies in RHIC with lessons for the LHC

    SciTech Connect

    Fischer, W.; Luo, Y.; Abreu, N.; Calaga, R.; Montag, C.; Robert-Demolaize, G.; Dorda, U.; Koutchouk, J.-P.; Sterbini, G.; Zimmermann, F.; Kim, H.-J.; Sen, T.; Shiltsev, V.; Valishev, A.; Qiang, J.; Kabel, A.

    2009-01-12

    Long-range as well as head-on beam-beam effects are expected to limit the LHC performance with design parameters. They are also important consideration for the LHC upgrades. To mitigate long-range effects, current carrying wires parallel to the beam were proposed. Two such wires are installed in RHIC where they allow studying the effect of strong long-range beam-beam effects, as well as the compensation of a single long-range interaction. The tests provide benchmark data for simulations and analytical treatments. Electron lenses were proposed for both RHIC and the LHC to reduce the head-on beam-beam effect. We present the experimental long-range beam-beam program at RHIC and report on head-on compensations studies based on simulations.

  20. Neutral beam source commercialization study. Final report

    SciTech Connect

    King, H.J.

    1980-06-01

    The basic tasks of this Phase II project were to: generate a set of design drawings suitable for quantity production of sources of this design; fabricate a functional neutral beam source incorporating as many of the proposed design changes as proved feasible; and document the procedures and findings developed during the contract. These tasks have been accomplished and represent a demonstrated milestone in the industrialization of this complete device.

  1. A biomechanical study comparing helical blade with screw design for sliding hip fixations of unstable intertrochanteric fractures.

    PubMed

    Luo, Qiang; Yuen, Grace; Lau, Tak-Wing; Yeung, Kelvin; Leung, Frankie

    2013-01-01

    Dynamic hip screw (DHS) is a well-established conventional implant for treating intertrochanteric fracture. However, revision surgery sometimes still occurs due to the cutting out of implants. A helical blade instead of threaded screw (DHS blade) was designed to improve the fixation power of the osteoporotic intertrochanteric fracture. In this study, the biomechanical properties of DHS blade compared to the conventional DHS were evaluated using an unstable AO/OTA 31-A2 intertrochanteric fracture model. Fifty synthetic proximal femoral bone models with such configuration were fixed with DHS and DHS blade in five different positions: centre-centre (CC), superior-centre (SC), inferior-center (IC), centre-anterior (CA), and centre-posterior (CP). All models had undergone mechanical compression test, and the vertical and rotational displacements were recorded. The results showed that DHS blade had less vertical or rotational displacement than the conventional DHS in CC, CA, and IC positions. The greatest vertical and rotational displacements were found at CP position in both groups. Overall speaking, DHS blade was superior in resisting vertical or rotational displacement in comparison to conventional DHS, and the centre-posterior position had the poorest performance in both groups.

  2. Eccentric and concentric loading of the triceps surae: an in vivo study of dynamic muscle and tendon biomechanical parameters.

    PubMed

    Chaudhry, Saira; Morrissey, Dylan; Woledge, Roger C; Bader, Dan L; Screen, Hazel R C

    2015-04-01

    Triceps surae eccentric exercise is more effective than concentric exercise for treating Achilles tendinopathy, however the mechanisms underpinning these effects are unclear. This study compared the biomechanical characteristics of eccentric and concentric exercises to identify differences in the tendon load response. Eleven healthy volunteers performed eccentric and concentric exercises on a force plate, with ultrasonography, motion tracking, and EMG applied to measure Achilles tendon force, lower limb movement, and leg muscle activation. Tendon length was ultrasonographically tracked and quantified using a novel algorithm. The Fourier transform of the ground reaction force was also calculated to investigate for tremor, or perturbations. Tendon stiffness and extension did not vary between exercise types (P = .43). However, tendon perturbations were significantly higher during eccentric than concentric exercises (25%-40% higher, P = .02). Furthermore, perturbations during eccentric exercises were found to be negatively correlated with the tendon stiffness (R2 = .59). The particular efficacy of eccentric exercise does not appear to result from variation in tendon stiffness or extension within a given session. However, varied perturbation magnitude may have a role in mediating the observed clinical effects. This property is subject-specific, with the source and clinical time-course of such perturbations requiring further research.

  3. Biomechanical effect of altered lumbar lordosis on intervertebral lumbar joints during the golf swing: a simulation study.

    PubMed

    Bae, Tae Soo; Cho, Woong; Kim, Kwon Hee; Chae, Soo Won

    2014-11-01

    Although the lumbar spine region is the most common site of injury in golfers, little research has been done on intervertebral loads in relation to the anatomical-morphological differences in the region. This study aimed to examine the biomechanical effects of anatomical-morphological differences in the lumbar lordosis on the lumbar spinal joints during a golf swing. The golf swing motions of ten professional golfers were analyzed. Using a subject-specific 3D musculoskeletal system model, inverse dynamic analyses were performed to compare the intervertebral load, the load on the lumbar spine, and the load in each swing phase. In the intervertebral load, the value was the highest at the L5-S1 and gradually decreased toward the T12. In each lumbar spine model, the load value was the greatest on the kypholordosis (KPL) followed by normal lordosis (NRL), hypolordosis (HPL), and excessive lordosis (EXL) before the impact phase. However, results after the follow-through (FT) phase were shown in reverse order. Finally, the load in each swing phase was greatest during the FT phase in all the lumbar spine models. The findings can be utilized in the training and rehabilitation of golfers to help reduce the risk of injury by considering individual anatomical-morphological characteristics.

  4. Polarization Studies in Fast-Ion Beam Spectroscopy

    SciTech Connect

    Trabert, E

    2001-12-20

    In a historical review, the observations and the insight gained from polarization studies of fast ions interacting with solid targets are presented. These began with J. Macek's recognition of zero-field quantum beats in beam-foil spectroscopy as indicating alignment, and D.G. Ellis' density operator analysis that suggested the observability of orientation when using tilted foils. Lastly H. Winter's studies of the ion-beam surface interaction at grazing incidence yielded the means to produce a high degree of nuclear orientation in ion beams.

  5. Cellular track model for study of heavy ion beams

    NASA Technical Reports Server (NTRS)

    Shinn, Judy L.; Katz, Robert; Cucinotta, Francis A.; Wilson, John W.; Ngo, Duc M.

    1993-01-01

    Track theory is combined with a realistic model of a heavy ion beam to study the effects of nuclear fragmentation on cell survival and biological effectiveness. The effects of secondary reaction products are studied as a function of depth in a water column. Good agreement is found with experimental results for the survival of human T-l cells exposed to monoenergetic carbon, neon, and argon beams under aerobic and hypoxia conditions. The present calculation, which includes the effect of target fragmentation, is a significant improvement over an earlier calculation because of the use of a vastly improved beam model with no change in the track theory or cellular response parameters.

  6. Studies of beam dynamics in relativistic klystron two-beam accelerators

    SciTech Connect

    Lidia, Steven M.

    1999-11-01

    Two-beam accelerators (TBAs) based upon free-electron lasers (FELs) or relativistic klystrons (RK-TBAs) have been proposed as efficient power sources for next generation high-energy linear colliders. Studies have demonstrated the possibility of building TBAs from X-band (~8-12 GHz) through Ka band (~ 30-35 GHz) frequency regions. Provided that further prototyping shows stable beam propagation with minimal current loss and production of good quality, high-power rf fields, this technology is compatible with current schemes for electron-positron colliders in the multi-TeV center-of-mass scale. A new method of simulating the beam dynamics in accelerators of this type has been developed in this dissertation. There are three main components to this simulation. The first is a tracking algorithm to generate nonlinear transfer maps for pushing noninteracting particles through the external fields. The second component is a 3D Particle-In-Cell (PIC) algorithm that solves a set of Helmholtz equations for the self-fields, including the conducting boundary condition, and generates impulses that are interleaved with the nonlinear maps by means of a split-operation algorithm. The Helmholtz equations are solved by a multi-grid algorithm. The third component is an equivalent circuit equation solver that advances the modal rf cavity fields in time due to excitation by the modulated beam. The RTA project is described, and the simulation code is used to design the latter portions of the experiment. Detailed calculations of the beam dynamics and of the rf cavity output are presented and discussed. A beamline design is presented that will generate nearly 1.2 GW of power from 40 input, gain, and output rv cavities over a 10 m distance. The simulations show that beam current losses are acceptable, and that longitudinal and transverse focusing techniques are sufficient capable of maintaining a high degree of beam quality along the entire beamline. Additional experimental efforts are also

  7. Molecular beam studies of reaction dynamics

    SciTech Connect

    Lee, Y.T.

    1987-03-01

    Purpose of this research project is two-fold: (1) to elucidate detailed dynamics of simple elementary reactions which are theoretically important and to unravel the mechanism of complex chemical reactions or photo chemical processes which play an important role in many macroscopic processes and (2) to determine the energetics of polyatomic free radicals using microscopic experimental methods. Most of the information is derived from measurement of the product fragment translational energy and angular distributions using unique molecular beam apparati designed for these purposes.

  8. Biomechanical patterns of text-message distraction.

    PubMed

    Le, Peter; Hwang, Jaejin; Grawe, Sarah; Li, Jing; Snyder, Alison; Lee, Christina; Marras, William S

    2015-01-01

    The objective of this study was to identify biomechanical measures that can distinguish texting distraction in a laboratory-simulated driving environment. The goal would be to use this information to provide an intervention for risky driving behaviour. Sixteen subjects participated in this study. Three independent variables were tested: task (texting, visual targeting, weighted and non-weighted movements), task direction (front and side) and task distance (close and far). Dependent variables consisted of biomechanical moments, head displacement and the length of time to complete each task. Results revealed that the time to complete each task was higher for texting compared to other tasks. Peak moments during texting were only distinguishable from visual targeting. Peak head displacement and cumulative biomechanical exposure measures indicated that texting can be distinguished from other tasks. Therefore, it may be useful to take into account both temporal and biomechanical measures when considering warning systems to detect texting distraction.

  9. Spes: Exotic Beams for Nuclear Physics Studies

    NASA Astrophysics Data System (ADS)

    Andrighetto, Alberto; Manzolaro, Mattia; Corradetti, Stefano; Scarpa, Daniele; Vasquez, Jesu; Rossignoli, Massimo; Monetti, Alberto; Calderolla, Michele; Prete, Gianfranco

    2014-02-01

    The SPES project at Laboratori di Legnaro of INFN (Italy) is concentrating on the production of neutron-rich radioactive nuclei for nuclear physics experiments using uranium fission at a rate of 1013 fission/s. The emphasis on neutron-rich isotopes is justified by the fact that this vast territory has been little explored. The Radioactive Ion Beam (RIB) will be produced by the ISOL technique using proton induced fission on a direct target of UCx. The most critical element of the SPES project is the Multi-Foil Direct Target. Up to the present time, the proposed target represents an innovation in terms of its capability to sustain the primary beam power. This talk will present the status of the project financed by INFN, which is actually in the construction phase at Legnaro. In particular, developments related to the target and the ion-source activities using the surface ion source, plasma ion source, and laser ion source techniques will be reported.

  10. Biomechanics of Gait during Pregnancy

    PubMed Central

    Vieira, Filomena

    2014-01-01

    Introduction. During pregnancy women experience several changes in the body's physiology, morphology, and hormonal system. These changes may affect the balance and body stability and can cause discomfort and pain. The adaptations of the musculoskeletal system due to morphological changes during pregnancy are not fully understood. Few studies clarify the biomechanical changes of gait that occur during pregnancy and in postpartum period. Purposes. The purpose of this review was to analyze the available evidence on the biomechanical adaptations of gait that occur throughout pregnancy and in postpartum period, specifically with regard to the temporal, spatial, kinematic, and kinetic parameters of gait. Methods. Three databases were searched and 9 studies with a follow-up design were retrieved for analysis. Results. Most studies performed temporal, spatial, and kinematic analysis. Only three studies performed kinetic analysis. Conclusion. The adaptation strategies to the anatomical and physiological changes throughout pregnancy are still unclear, particularly in a longitudinal perspective and regarding kinetic parameters. PMID:25587566

  11. Study of the bending vibration characteristic of phononic crystals beam-foundation structures by Timoshenko beam theory

    NASA Astrophysics Data System (ADS)

    Zhang, Yan; Ni, Zhi-Qiang; Jiang, Lin-Hua; Han, Lin; Kang, Xue-Wei

    2015-07-01

    Vibration problems wildly exist in beam-foundation structures. In this paper, finite periodic composites inspired by the concept of ideal phononic crystals (PCs), as well as Timoshenko beam theory (TBT), are proposed to the beam anchored on Winkler foundation. The bending vibration band structure of the PCs Timoshenko beam-foundation structure is derived from the modified transfer matrix method (MTMM) and Bloch's theorem. Then, the frequency response of the finite periodic composite Timoshenko beam-foundation structure by the finite element method (FEM) is performed to verify the above theoretical deduction. Study shows that the Timoshenko beam-foundation structure with periodic composites has wider attenuation zones compared with homogeneous ones. It is concluded that TBT is more available than Euler beam theory (EBT) in the study of the bending vibration characteristic of PCs beam-foundation structures with different length-to-height ratios.

  12. A Biomechanical Modeling Study of the Effects of the Orbicularis Oris Muscle and Jaw Posture on Lip Shape

    ERIC Educational Resources Information Center

    Stavness, Ian; Nazari, Mohammad Ali; Perrier, Pascal; Demolin, Didier; Payan, Yohan

    2013-01-01

    Purpose: The authors' general aim is to use biomechanical models of speech articulators to explore how possible variations in anatomical structure contribute to differences in articulatory strategies and phone systems across human populations. Specifically, they investigated 2 issues: (a) the link between lip muscle anatomy and variability in…

  13. Course setting and selected biomechanical variables related to injury risk in alpine ski racing: an explorative case study

    PubMed Central

    Spörri, Jörg; Kröll, Josef; Schwameder, Hermann; Schiefermüller, Christian; Müller, Erich

    2012-01-01

    Background Course setting has often been discussed as a potential preventative measure in the World Cup ski-racing community. However, there is limited understanding of how it is related to injury risk. Objective This study was undertaken to investigate the effect of increased horizontal gate distance on energy-related and injury mechanism-related variables. Methods During a video-based three-dimensional (3D)-kinematic field measurement, a top world-class racer performed giant slalom runs at two course settings with different horizontal gate distances. A full-body segment model was reconstructed in 3D and selected biomechanical parameters were calculated. Results For the analysed turn, no significant differences were found in turn speed for increased horizontal gate distance. However, a large effect size was observed for speed reduction towards the end of the turn. Turn forces were by tendency higher at the beginning and significantly higher towards the end of the turn. Additionally, significant differences were found in higher inward leaning, and large effect sizes were observed for a decreased fore/aft position after gate passage. Conclusions On the basis of the data of this study, no final conclusion can be made about whether, for a section of consecutive turns, increasing horizontal gate distance is an effective tool for speed reduction. However, this study pointed out two major drawbacks of this course setting modification: (1) it may increase fatigue as a consequence of loading forces acting over a longer duration; (2) it may increase the risk of out-of-balance situations by forcing the athlete to exhaust his backward and inward leaning spectrum. PMID:22983120

  14. BEAM-BEAM 2003 SUMMARY.

    SciTech Connect

    FISCHER,W.SEN,T.

    2003-05-19

    This paper summarizes the presentations and discussions of the Beam-Beam'03 workshop, held in Montauk, Long Island, from May 19 to 23, 2003. Presentations and discussions focused on halo generation from beam-beam interactions; beam-beam limits, especially coherent limits and their effects on existing and future hadron colliders; beam-beam compensation techniques, particularly for long-range interactions; and beam-beam study tools in theory, simulation, and experiment.

  15. Propulsion phase of the single leg triple hop test in women with patellofemoral pain syndrome: a biomechanical study.

    PubMed

    Bley, Andre Serra; Correa, João Carlos Ferrari; Dos Reis, Amir Curcio; Rabelo, Nayra Deise Dos Anjos; Marchetti, Paulo Henrique; Lucareli, Paulo Roberto Garcia

    2014-01-01

    Asymmetry in the alignment of the lower limbs during weight-bearing activities is associated with patellofemoral pain syndrome (PFPS), caused by an increase in patellofemoral (PF) joint stress. High neuromuscular demands are placed on the lower limb during the propulsion phase of the single leg triple hop test (SLTHT), which may influence biomechanical behavior. The aim of the present cross-sectional study was to compare kinematic, kinetic and muscle activity in the trunk and lower limb during propulsion in the SLTHT using women with PFPS and pain free controls. The following measurements were made using 20 women with PFPS and 20 controls during propulsion in the SLTHT: kinematics of the trunk, pelvis, hip, and knee; kinetics of the hip, knee and ankle; and muscle activation of the gluteus maximus (GM), gluteus medius (GMed), biceps femoris (BF) and vastus lateralis (VL). Differences between groups were calculated using three separate sets of multivariate analysis of variance for kinematics, kinetics, and electromyographic data. Women with PFPS exhibited ipsilateral trunk lean; greater trunk flexion; greater contralateral pelvic drop; greater hip adduction and internal rotation; greater ankle pronation; greater internal hip abductor and ankle supinator moments; lower internal hip, knee and ankle extensor moments; and greater GM, GMed, BL, and VL muscle activity. The results of the present study are related to abnormal movement patterns in women with PFPS. We speculated that these findings constitute strategies to control a deficient dynamic alignment of the trunk and lower limb and to avoid PF pain. However, the greater BF and VL activity and the extensor pattern found for the hip, knee, and ankle of women with PFPS may contribute to increased PF stress.

  16. Slow positron beam generator for lifetime studies

    NASA Technical Reports Server (NTRS)

    Singh, Jag J. (Inventor); Eftekhari, Abe (Inventor); St.clair, Terry L. (Inventor)

    1991-01-01

    A slow positron beam generator uses a conductive source residing between two test films. Moderator pieces are placed next to the test film on the opposite side of the conductive source. A voltage potential is applied between the moderator pieces and the conductive source. Incident energetic positrons: (1) are emitted from the conductive source; (2) are passed through test film; and (3) isotropically strike moderator pieces before diffusing out of the moderator pieces as slow positrons, respectively. The slow positrons diffusing out of moderator pieces are attracted to the conductive source which is held at an appropriate potential below the moderator pieces. The slow positrons have to pass through the test films before reaching the conductive source. A voltage is adjusted so that the potential difference between the moderator pieces and the conductive source forces the positrons to stop in the test films. Measurable annihilation radiation is emitted from the test film when positrons annihilate (combine) with electrons in the test film.

  17. Ionosphere/microwave beam interaction study

    NASA Technical Reports Server (NTRS)

    Gordon, W. E.; Duncan, L. M.

    1978-01-01

    The microwave beam of the Solar Power Satellite (SPS) is predicted to interact with the ionosphere producing thermal runaway up to an altitude of about 100 kilometers at a power density threshold of 12 mW/cm sq (within a factor of two). The operation of the SPS at two frequencies, 2450 and 5800 MHz, is compared. The ionosphere interaction is less at the higher frequency, but the tropospheric problem scattering from heavy rain and hail is worse at the higher frequency. Microwave signals from communication satellites were observed to scintillate, but there is some concern that the uplink pilot signal may be distorted by the SPS heated ionosphere. The microwave scintillations are only observed in the tropics in the early evenings near the equinoxes. Results indicate that large phase errors in the uplink pilot signal can be reduced.

  18. Positron beam studies of transients in semiconductors

    NASA Astrophysics Data System (ADS)

    Beling, C. D.; Ling, C. C.; Cheung, C. K.; Naik, P. S.; Zhang, J. D.; Fung, S.

    2006-02-01

    Vacancy-sensing positron deep level transient spectroscopy (PDLTS) is a positron beam-based technique that seeks to provide information on the electronic ionization levels of vacancy defects probed by the positron through the monitoring of thermal transients. The experimental discoveries leading to the concept of vacancy-sensing PDLTS are first reviewed. The major problem associated with this technique is discussed, namely the strong electric fields establish in the near surface region of the sample during the thermal transient which tend to sweep positrons into the contact with negligible defect trapping. New simulations are presented which suggest that under certain conditions a sufficient fraction of positrons may be trapped into ionizing defects rendering PDLTS technique workable. Some suggestions are made for techniques that might avoid the problematic electric field problem, such as optical-PDLTS where deep levels are populated using light and the use of high forward bias currents for trap filling.

  19. High-precision satellite positioning system as a new tool to study the biomechanics of human locomotion.

    PubMed

    Terrier, P; Ladetto, Q; Merminod, B; Schutz, Y

    2000-12-01

    New Global Positioning System (GPS) receivers allow now to measure a location on earth at high frequency (5Hz) with a centimetric precision using phase differential positioning method. We studied whether such technique was accurate enough to retrieve basic parameters of human locomotion. Eight subjects walked on an athletics track at four different imposed step frequencies (70-130steps/min) plus a run at free pace. Differential carrier phase localization between a fixed base station and the mobile antenna mounted on the walking person was calculated. In parallel, a triaxial accelerometer, attached to the low back, recorded body accelerations. The different parameters were averaged for 150 consecutive steps of each run for each subject (total of 6000 steps analyzed). We observed a perfect correlation between average step duration measured by accelerometer and by GPS (r=0.9998, N=40). Two important parameters for the calculation of the external work of walking were also analyzed, namely the vertical lift of the trunk and the velocity variation per step. For an average walking speed of 4.0km/h, average vertical lift and velocity variation were, respectively, 4.8cm and 0.60km/h. The average intra-individual step-to-step variability at a constant speed, which includes GPS errors and the biological gait style variation, were found to be 24. 5% (coefficient of variation) for vertical lift and 44.5% for velocity variation. It is concluded that GPS technique can provide useful biomechanical parameters for the analysis of an unlimited number of strides in an unconstrained free-living environment.

  20. Biomechanically Engineered Athletes.

    ERIC Educational Resources Information Center

    Perry, Tekla S.

    1991-01-01

    The real-world meeting of electronics, computer monitoring, control systems, and mathematics, introduced in the context of sports, is described. Recent advances in the field of biomechanics and its use in improving athletic performance are discussed. (KR)

  1. Biomechanics and tennis

    PubMed Central

    Elliott, B

    2006-01-01

    Success in tennis requires a mix of player talent, good coaching, appropriate equipment, and an understanding of those aspects of sport science pertinent to the game. This paper outlines the role that biomechanics plays in player development from sport science and sport medicine perspectives. Biomechanics is a key area in player development because all strokes have a fundamental mechanical structure and sports injuries primarily have a mechanical cause. PMID:16632567

  2. Optics Studies of the LHC Beam Transfer Line TI8

    SciTech Connect

    J. Wenninger; G. Arduini; B. Goddard; D. Jacquet; V. Kain; M. Lamont; V. Mertens; J.A. Uythoven; Y.-C. Chao

    2005-05-16

    The optics of the newly commissioned LHC beam transfer line TI 8 was studied with beam trajectories, dispersion and profile measurements. Steering magnet response measurements were used to analyze the quality of the steering magnets and of the beam position monitors. A simultaneous fit of the quadrupole strengths was used to search for setting or calibration errors. Residual coupling between the planes was evaluated using high statistics samples of trajectories. Initial conditions for the optics at the entrance of the transfer line were reconstructed from beam profile measurements with Optical Transition Radiation monitors. The paper presents the various analysis methods and their errors. The expected emittance growth arising from optical mismatch into the LHC is evaluated.

  3. A Study to Determine the Biomechanics of Running in Skilled Trackmen. Final Report.

    ERIC Educational Resources Information Center

    Nelson, Richard C.

    The purpose of this study is to investigate the manner in which selected mechanical elements of the running stride are altered with accompanying variations in the speed of running and the slope upon which running occurs. Subjects, 16 intercollegiate runners, were marked at reference points of the body pertinent to this study and filmed twice…

  4. Study of the beam profile and position instability of a post-accelerated pseudospark-sourced electron beam

    NASA Astrophysics Data System (ADS)

    Zhao, J.; Yin, H.; Zhang, L.; Shu, G.; He, W.; Phelps, A. D. R.; Cross, A. W.; Pang, L.; Zhang, Q.

    2017-03-01

    A pseudospark-sourced electron beam is a promising candidate for driving a THz millimeter wave radiation source. However, the physics governing the electron beam density profile and the beam center deviation from the axis of the structure, which may be caused by the randomness in the pseudospark discharge process, remains still unclear especially for the high energy component of the pseudospark-sourced electron beam, which is usually non-mono-energetic. It is essential to study the electron beam density profile and the beam center position distribution for optimizing the pseudospark discharge configuration. In this paper, images of some single-shot electron beam pulses have been captured using a 50 μm thickness stopping copper foil and a phosphor screen coated with a P47 scintillator to study the electron beam density profile and the beam center position distribution of the high energy component of the electron beam. The experiments have been carried out on two pseudospark discharge configurations with two different size hollow cathode cavities. The influence of the cathode aperture of each configuration has also been studied according to the beam images. Experimental results show that the beam profile of the high energy component has a Lorentzian distribution and is much smaller than the axial aperture size with the beam centers dispersing within a certain range around the axis of the discharge structure. The pseudospark-sourced electron beam with a larger hollow cathode cavity shows a smaller full width at half maximum radius and a more concentrated beam center distribution.

  5. Ion source studies for particle beam accelerators

    SciTech Connect

    Bieg, K.W.; Burns, E.J.T.; Olsen, J.N.; Dorrell, L.R.

    1985-05-01

    High power particle beam accelerators are being developed for use in inertial confinement fusion applications. These pulsed power accelerators require sources of low atomic number ions (e.g., protons, deuterons, carbon, or lithium). The sources must be of high purity for efficient accelerator operation and proper target coupling, must have a rapid ''turn-on,'' and must be compatible with ion diode configurations under development. A particular type of source presently being investigated is the flashover ion source which generates ions by means of the vacuum flashover of an insulating anode material when the high voltage pulse arrives at the diode. We have developed an applied-magnetic-field, extraction ion diode for the 0.03 TW Nereus accelerator specifically to investigate these sources. Extracted ion species are measured by means of a Thomson-parabola ion analyzer, dB/dt current monitors, and Faraday cups. Experiments have been performed to investigate the surface flashover mechanism and the effects of various dielectric source materials, anode preparation methods (including rf glow discharge cleaning), and vacuum conditions on ion species and diode operation.

  6. A surface energy spectral study on the bone heterogeneity and beam obliquity using the flattened and unflattened photon beams

    PubMed Central

    Chow, James C.L.; Owrangi, Amir M.

    2016-01-01

    Aim Using flattened and unflattened photon beams, this study investigated the spectral variations of surface photon energy and energy fluence in the bone heterogeneity and beam obliquity. Background Surface dose enhancement is a dosimetric concern when using unflattened photon beam in radiotherapy. It is because the unflattened photon beam contains more low-energy photons which are removed by the flattening filter of the flattened photon beam. Materials and methods We used a water and bone heterogeneity phantom to study the distributions of energy, energy fluence and mean energy of the 6 MV flattened and unflattened photon beams (field size = 10 cm × 10 cm) produced by a Varian TrueBEAM linear accelerator. These elements were calculated at the phantom surfaces using Monte Carlo simulations. The photon energy and energy fluence calculations were repeated with the beam angle turned from 0° to 15°, 30° and 45° in the water and bone phantom. Results Spectral results at the phantom surfaces showed that the unflattened photon beams contained more photons concentrated mainly in the low-energy range (0–2 MeV) than the flattened beams associated with a flattening filter. With a bone layer of 1 cm under the phantom surface and within the build-up region of the 6 MV photon beam, it is found that both the flattened and unflattened beams had slightly less photons in the energy range <0.4 MeV compared to the water phantom. This shows that the presence of the bone decreased the low-energy photon backscatters to the phantom surface. When both the flattened and unflattened photon beams were rotated from 0° to 45°, the number of photon and mean photon energy increased. This indicates that both photon beams became more hardened or penetrate when the beam angle increased. In the presence of bone, the mean energies of both photon beams increased. This is due to the absorption of low-energy photons by the bone, resulting in more beam hardening. Conclusions This study

  7. Nuclear photofission studies with monochromatic γ ray beams

    NASA Astrophysics Data System (ADS)

    Csige, L.; Gulyás, J.; Habs, D.; Krasznahorkay, A.; Thirolf, P. G.; Tornyi, T. G.

    2012-07-01

    Two new research facilities will be ready for operation very soon (MEGa-Ray at Liver-more National Laboratory) or start construction (ELI-Nuclear Physics in Bucharest), both providing highly brilliant γ beams with so far unprecedented properties via Compton backscattering of laser photons from a high-quality, relativistic electron beam. With these intense, monochromatic γ beams, a new era of photonuclear physics will be enabled. A new research campaign is proposed to exploit the unprecedented properties of these highly-brilliant, novel γ beams on highly-selective studies of extremely deformed nuclei in the multiple-humped potential energy landscape of the actinides via photofission. With the unique γ beam bandwidth of ΔE/E = 10-3, we can aim at resolving individual resonances which could never be achieved so far due to the limited γ bandwidth of bremsstrahlung beams. Exploratory, non-bremsstrahlung photofission experiments are going to be performed very soon at the HIγS facility (Duke University, USA) to investigate the fine structure of the sub-barrier transmission resonances of the actinides.

  8. Nuclear photofission studies with monochromatic {gamma} ray beams

    SciTech Connect

    Csige, L.; Gulyas, J.; Habs, D.; Krasznahorkay, A.; Thirolf, P. G.; Tornyi, T. G.

    2012-07-09

    Two new research facilities will be ready for operation very soon (MEGa-Ray at Liver-more National Laboratory) or start construction (ELI-Nuclear Physics in Bucharest), both providing highly brilliant {gamma} beams with so far unprecedented properties via Compton backscattering of laser photons from a high-quality, relativistic electron beam. With these intense, monochromatic {gamma} beams, a new era of photonuclear physics will be enabled. A new research campaign is proposed to exploit the unprecedented properties of these highly-brilliant, novel {gamma} beams on highly-selective studies of extremely deformed nuclei in the multiple-humped potential energy landscape of the actinides via photofission. With the unique {gamma} beam bandwidth of {Delta}E/E = 10{sup -3}, we can aim at resolving individual resonances which could never be achieved so far due to the limited {gamma} bandwidth of bremsstrahlung beams. Exploratory, non-bremsstrahlung photofission experiments are going to be performed very soon at the HI{gamma}S facility (Duke University, USA) to investigate the fine structure of the sub-barrier transmission resonances of the actinides.

  9. The effect of a cadence retraining protocol on running biomechanics and efficiency: a pilot study.

    PubMed

    Hafer, Jocelyn F; Brown, Allison M; deMille, Polly; Hillstrom, Howard J; Garber, Carol Ewing

    2015-01-01

    Many studies have documented the association between mechanical deviations from normal and the presence or risk of injury. Some runners attempt to change mechanics by increasing running cadence. Previous work documented that increasing running cadence reduces deviations in mechanics tied to injury. The long-term effect of a cadence retraining intervention on running mechanics and energy expenditure is unknown. This study aimed to determine if increasing running cadence by 10% decreases running efficiency and changes kinematics and kinetics to make them less similar to those associated with injury. Additionally, this study aimed to determine if, after 6 weeks of cadence retraining, there would be carryover in kinematic and kinetic changes from an increased cadence state to a runner's preferred running cadence without decreased running efficiency. We measured oxygen uptake, kinematic and kinetic data on six uninjured participants before and after a 6-week intervention. Increasing cadence did not result in decreased running efficiency but did result in decreases in stride length, hip adduction angle and hip abductor moment. Carryover was observed in runners' post-intervention preferred running form as decreased hip adduction angle and vertical loading rate.

  10. IMMEDIATE AND LATE EFFECT OF SUTURES IN EXTRASYNOVIAL TENDONS: BIOMECHANICAL STUDY IN RATS

    PubMed Central

    Sardenberg, Trajano; Muller, Sérgio Swain; Garms, Luciana Zauhy; Miduati, Francini Belluci

    2015-01-01

    Objective: The aim of this study was to evaluate the effects on the mechanical properties of rats’ calcaneus tendons, of repair arrangements using suture material in the absence of any healing process. Method: Twelve male Wistar rats were used. They were subjected to placement of a modified Kessler suture stitch in the calcaneus tendon. The sacrifices were performed immediately after and six weeks after the operation. The mechanical properties studied were maximum load, tension in the maximum load and module of elasticity. The contralateral tendon was used as a control. Results: The statistical analysis showed that for the times studied, the values for mechanical properties did not present any significant differences. In relation to the control, i.e. the contralateral tendon without a suture, the results demonstrated that, six weeks after the operation, the values for the modulus of elasticity were lower, whereas there were no significant variations in maximum load or tension at maximum load. Conclusion: Placement of suture material on an extrasynovial tendon without lesions decreased the modulus of elasticity, but it did not interfere with the maximum load or tension at maximum load, six weeks after the operation. PMID:27047823

  11. The effect of cement on hip stem fixation: a biomechanical study.

    PubMed

    Çelik, Talip; Mutlu, İbrahim; Özkan, Arif; Kişioğlu, Yasin

    2017-03-20

    This study presents the numerical analysis of stem fixation in hip surgery using with/without cement methods since the use of cement is still controversial based on the clinical studies in the literature. Many different factors such as stress shielding, aseptic loosening, material properties of the stem, surgeon experiences etc. play an important role in the failure of the stem fixations. The stem fixation methods, cemented and uncemented, were evaluated in terms of mechanical failure aspects using computerized finite element method. For the modeling processes, three dimensional (3D) femur model was generated from computerized tomography (CT) images taken from a patient using the MIMICS Software. The design of the stem was also generated as 3D CAD model using the design parameters taken from the manufacturer catalogue. These 3D CAD models were generated and combined with/without cement considering the surgical procedure using SolidWorks program and then imported into ANSYS Workbench Software. Two different material properties, CoCrMo and Ti6Al4V, for the stem model and Poly Methyl Methacrylate (PMMA) for the cement were assigned. The material properties of the femur were described according to a density calculated from the CT images. Body weight and muscle forces were applied on the femur and the distal femur was fixed for the boundary conditions. The calculations of the stress distributions of the models including cement and relative movements of the contacts examined to evaluate the effects of the cement and different stem material usage on the failure of stem fixation. According to the results, the use of cement for the stem fixation reduces the stress shielding but increases the aseptic loosening depending on the cement crack formations. Additionally, using the stiffer material for the stem reduces the cement stress but increases the stress shielding. Based on the results obtained in the study, even when taking the disadvantages into account, the cement usage

  12. The application of biomechanics to penalty corner drag-flick training: a case study.

    PubMed

    de Subijana, Cristina López; Juárez, Daniel; Mallo, Javier; Navarro, Enrique

    2011-01-01

    The penalty corner is one of the most important game situations in field hockey with one third of all goals resulting from this tactical situation. The aim of this study was to develop and apply a training method, based on previous studies, to improve the drag- flick skill on a young top-class field hockey player. A young top-class player exercised three times per week using specific drills over a four week period. A VICON optoelectronic system (Oxford Metrics, Oxford, UK) was employed to capture twenty drag-flicks, with six cameras sampling at 250 Hz, prior and after the training period. In order to analyze pre- and post-test differences a dependent t-test was carried out. Angular velocities and the kinematic sequence were similar to previous studies. The player improved (albeit not significantly) the angular velocity of the stick. The player increased front foot to the ball at T1 (p < 0.01) and the drag-flick distances. The range of motion from the front leg decreased from T1 to T6 after the training period (p < 0.01). The specific training sessions conducted with the player improved some features of this particular skill. This article shows how technical knowledge can help with the design of training programs and whether some drills are more effective than others. Key pointsThis article adds information about the drag-flick kinematics.This article adds information about how to train the drag-flick.The drag-flick is the most efficient technique shooting for goal after a penalty corner.

  13. Coupled Biomechanical Response of the Cornea Assessed by Non-Contact Tonometry. A Simulation Study

    PubMed Central

    2015-01-01

    The mechanical response of the cornea subjected to a non-contact air-jet tonometry diagnostic test represents an interplay between its geometry, the corneal material behavior and the loading. The objective is to study this interplay to better understand and interpret the results obtained with a non-contact tonometry test. A patient-specific finite element model of a healthy eye, accounting for the load free configuration, was used. The corneal tissue was modeled as an anisotropic hyperelastic material with two preferential directions. Three different sets of parameters within the human experimental range obtained from inflation tests were considered. The influence of the IOP was studied by considering four pressure levels (10–28 mmHg) whereas the influence of corneal thickness was studied by inducing a uniform variation (300–600 microns). A Computer Fluid Dynamics (CFD) air-jet simulation determined pressure loading exerted on the anterior corneal surface. The maximum apex displacement showed a linear variation with IOP for all materials examined. On the contrary, the maximum apex displacement followed a cubic relation with corneal thickness. In addition, a significant sensitivity of the apical displacement to the corneal stiffness was also obtained. Explanation to this behavior was found in the fact that the cornea experiences bending when subjected to an air-puff loading, causing the anterior surface to work in compression whereas the posterior surface works in tension. Hence, collagen fibers located at the anterior surface do not contribute to load bearing. Non-contact tonometry devices give useful information that could be misleading since the corneal deformation is the result of the interaction between the mechanical properties, IOP, and geometry. Therefore, a non-contact tonometry test is not sufficient to evaluate their individual contribution and a complete in-vivo characterization would require more than one test to independently determine the membrane

  14. Biomechanics of whiplash injury.

    PubMed

    Chen, Hai-bin; Yang, King H; Wang, Zheng-guo

    2009-10-01

    Despite a large number of rear-end collisions on the road and a high frequency of whiplash injuries reported, the mechanism of whiplash injuries is not completely understood. One of the reasons is that the injury is not necessarily accompanied by obvious tissue damage detectable by X-ray or MRI. An extensive series of biomechanics studies, including injury epidemiology, neck kinematics, facet capsule ligament mechanics, injury mechanisms and injury criteria, were undertaken to help elucidate these whiplash injury mechanisms and gain a better understanding of cervical facet pain. These studies provide the following evidences to help explain the mechanisms of the whiplash injury: (1) Whiplash injuries are generally considered to be a soft tissue injury of the neck with symptoms such as neck pain and stiffness, shoulder weakness, dizziness, headache and memory loss, etc. (2) Based on kinematical studies on the cadaver and volunteers, there are three distinct periods that have the potential to cause injury to the neck. In the first stage, flexural deformation of the neck is observed along with a loss of cervical lordosis; in the second stage, the cervical spine assumes an S-shaped curve as the lower vertebrae begin to extend and gradually cause the upper vertebrae to extend; during the final stage, the entire neck is extended due to the extension moments at both ends. (3) The in vivo environment afforded by rodent models of injury offers particular utility for linking mechanics, nociception and behavioral outcomes. Experimental findings have examined strains across the facet joint as a mechanism of whiplash injury, and suggested a capsular strain threshold or a vertebral distraction threshold for whiplash-related injury, potentially producing neck pain. (4) Injuries to the facet capsule region of the neck are a major source of post-crash pain. There are several hypotheses on how whiplash-associated injury may occur and three of these injuries are related to strains

  15. Biomechanics and Biotensegrity: Study Method and Frequency Response of the Simplex and 3-bar-SVD Tensegrity Configurations

    NASA Astrophysics Data System (ADS)

    Castro Arenas, C.; Ghersi, I.; Miralles, M. T.

    2016-04-01

    The purpose of this work is to study the frequency response of 3D tensegrity structures. These are structures that have been used, since the 80’s, to model biological systems of different scales. This fact led to the origin of the field of biotensegrity, which includes biomechanics as a natural field of application. In this work: a) A simple method for the analysis of frequency response of different nodes in 3D tensegrity structures was set up and tuned. This method is based on a video-analysis algorithm, which was applied to the structures, as they were vibrated along their axis of symmetry, at frequencies from 1 Hz to 60 Hz. b) Frequency-response analyses were performed, for the simplest 3D structure, the Simplex module, as well as for two towers, formed by stacking two and three Simplex modules, respectively. Resonant frequencies were detected for the Simplex module at (19.2±0.1) Hz and (50.2±0.1) Hz (the latter being an average of frequencies between homologous nodes). For the towers with two and three modules, each selected node presented a characteristic frequency response, modulated by their spatial placement in each model. Resonances for the two-stage tower were found at: (12±0.1) Hz; (16.2±0.1) Hz; (29.4±0.1) Hz and (37.2±0.1) Hz. For the tower with three Simplex modules, the main resonant frequencies were found at (12.0±0.1) Hz and (21.0±0.1) Hz. Results show that the proposed method is adequate for the study (2D) of any 3D tensegrity structure, with the potential of being generalized to the study of oscillations in three dimensions. A growing complexity and variability in the frequency response of the nodes was observed, as modules were added to the structures. These findings were compared to those found in the available literature.

  16. Hydrolyzed collagen improves bone metabolism and biomechanical parameters in ovariectomized mice: an in vitro and in vivo study.

    PubMed

    Guillerminet, Fanny; Beaupied, Hélène; Fabien-Soulé, Véronique; Tomé, Daniel; Benhamou, Claude-Laurent; Roux, Christian; Blais, Anne

    2010-03-01

    Collagen has an important structural function in several organs of the body, especially in bone and cartilage. The aim of this study was to investigate the effect of hydrolyzed collagen on bone metabolism, especially in the perspective of osteoporosis treatment and understanding of its mechanism of action. An in vivo study was carried out in 12-week-old female C3H/HeN mice. These were either ovariectomized (OVX) or sham-operated (SHAM) and fed for 12 weeks with a diet containing 10 or 25 g/kg of hydrolyzed collagen. We measured bone mineral density (BMD) using dual-energy X-ray absorptiometry (DXA). C-terminal telopeptide of type I collagen (CTX), marker of bone resorption, and alkaline phosphatase (ALP), marker of bone formation, were assayed after 4 and 12 weeks. Femur biomechanical properties were studied by a 3-point bending test and bone architecture by microtomography. The BMD for OVX mice fed the diet including 25 g/kg of hydrolyzed collagen was significantly higher as compared to OVX mice. The blood CTX level significantly decreased when mice were fed with either of the diets containing hydrolyzed collagen. Finally, we have shown a significant increase in bone strength correlated to geometrical changes for the OVX mice fed the 25 g/kg hydrolyzed collagen diet. Primary cultures of murine bone cells were established from the tibia and femur marrow of BALB/c mice. The growth and differentiation of osteoclasts and osteoblasts cultured with different concentrations (from 0.2 to 1.0 mg/mL) of bovine, porcine or fish hydrolyzed collagens (2 or 5 kDa) were measured. Hydrolyzed collagens (2 or 5 kDa) in the tissue culture medium did not have any significant effects on cell growth as compared to controls. However, there was a significant and dose-dependent increase in ALP activity, a well-known marker of osteogenesis, and a decrease in octeoclast activity in primary culture of bone cells cultured with hydrolyzed collagens (2 kDa only) as compared to the control. It

  17. Gliding resistance of flexor tendon associated with carpal tunnel pressure: a biomechanical cadaver study.

    PubMed

    Zhao, Chunfeng; Ettema, Anke M; Berglund, Lawrence J; An, Kai-Nan; Amadio, Peter C

    2011-01-01

    The purpose of this study was to investigate the effect of carpal tunnel pressure on the gliding characteristics of flexor tendons within the carpal tunnel. Eight fresh human cadaver wrists and hands were used. A balloon was inserted into the carpal tunnel to elevate the pressure. The mean gliding resistance of the middle finger flexor digitorum superficialis tendon was measured with the following six conditions: (1) as a baseline, before balloon insertion; (2) balloon with 0 mmHg pressure; (3) 30 mmHg; (4) 60 mmHg; (5) 90 mmHg; (6) 120 mmHg. The gliding resistance of flexor tendon gradually increased as the carpal tunnel pressure was elevated. At pressures above 60 mmHg, the increase in gliding resistance became significant compared to the baseline condition. This study helps us to understand the relationship between carpal tunnel pressure, which is elevated in the patient with carpal tunnel syndrome (CTS) and tendon gliding resistance, which is a component of the work of flexion. These findings suggest that patients with CTS may have to expend more energy to accomplish specific motions, which may in turn affect symptoms of hand pain, weakness and fatigue, seen commonly in such patients.

  18. Forces involved in lower limb lengthening: an in vivo biomechanical study.

    PubMed

    Lauterburg, Martin Th; Exner, G Ulrich; Jacob, Hilaire A C

    2006-09-01

    Despite improvements in surgical techniques for limb-lengthening procedures, the complication rate remains high. Bone fixators must cope with the forces involved during treatment, providing sufficient strength to maintain integrity of the limb in the course of lengthening, while permitting some "micromotion" across the bone gap that could enhance healing during the final phase of bone consolidation. This study reports on the forces generated during limb lengthening in the distraction and consolidation phases. Forces were measured on 19 patients between 6 and 22 years of age with 10 femoral and 11 tibial lengthenings of 1 mm/day by means of a monotube external fixator, fitted diaphysially, and modified to measure tension and weight-bearing forces. Peak force measured during the lengthening period amounted to about 14 N/kg of body mass. Generally, distraction forces leveled off at between 8 and 10 N/kg of body mass. During the consolidation period, the average force carried by the fixator dropped from 55% initially to about 10% of the force transmitted to the ground, consistent with increased load carrying capacity of the bone as healing progressed. Studying the forces involved in limb lengthening is important to gain knowledge of the forces required to overcome the resistance offered by the tissues that bridge the osteotomy site, to understand the biology of distraction osteogenesis and histiogenesis across the regenerate over time, and to provide scientific guidelines for frame removal.

  19. [Bond strength of a bioresorbable bone adhesive: results of a biomechanical study in a sheep model].

    PubMed

    Heiss, Christian; Schettler, Nicky; Schilke, Peter; Horas, Uwe; Kilian, Olaf; Meyer, Christof; Kraus, Ralf; Schnettler, Reinhard

    2008-04-01

    The purpose of this study was to investigate the bond strength of a new bone adhesive based on ethylene glycol-oligolactide-bismethacrylate on 36 sheep. A 2-cm metaphysial segment was produced on the ulna of each sheep by an oscillating saw and it was not stabilized by any type of additional osteosynthesis. Adhesive was applied to the osteotomy gaps in 18 sheep, the remaining 18 animals served as controls. A total of 6 animals with glue and 6 controls were euthanized after 21, 42 and 84 days. The bond strength after repair of the gaps through bone adhesive compared to a control group was studied by using a four-point bending test. There was a continual increase of bending stiffness from 21 to 84 days in all sheep, with the highest bending stiffness of 102.83 N/mm2 by the glue group after 84 days as opposed to the control group with 58.48 N/mm2 (p = 0.25). Morphological investigations showed more callus formation by the control group than the adhesive group after 84 days (p = 0.04). In addition, an in vitro gluing of the ulna segment was performed with a four-point bending test after 10, 60 and 360 min polymerization time. The in vitro gluing of the ulna segment showed a continual increase of bending stiffness to 17.32 N/mm2 after 360 min (p = 0.59).

  20. Experimental and constitutive modeling approaches for a study of biomechanical properties of human coronary arteries.

    PubMed

    Jankowska, Malgorzata A; Bartkowiak-Jowsa, Magdalena; Bedzinski, Romuald

    2015-10-01

    The study concerns the determination of mechanical properties of human coronary arterial walls with both experimental and constitutive modeling approaches. The research material was harvested from 18 patients (range 50-84 years). On the basis of hospital records and visual observation, each tissue sample was classified according to the stage (0, I, II, III) of atherosclerosis development (SAD). Then, strip samples considered as a membrane with the shape of rectangular parallelepiped were preconditioned and subjected to uniaxial tensile tests in longitudinal (n=27) and circumferential (n=4) direction. With experimental data obtained, the stress-strain characteristics were prepared. Furthermore, tensile strengths and related strains, stiffness coefficients and tangent modules of elasticity were computed. For a constitutive model of passive mechanical behavior of coronary arteries, values of material parameters were computed. The studies led to the following conclusions. Most importantly, the atherosclerotic changes affect all the mechanical properties of arterial walls. A progress of arteriosclerosis contributes to an increase of vascular stiffness. The highest values of the stiffness coefficients are obtained for the tissues in the advanced stage of the disease. We were also able to observe that gradual calcification, progression of atherosclerosis and degradation of collagen in the tissue caused a decrease of tensile strengths and related strains. Finally, a comparison made for the tissues with the advanced SAD showed that the tensile strengths and strains were much higher in the case of the samples with the circumferential orientation rather than those with the longitudinal one.

  1. Kinematic MRI study of upper-airway biomechanics using electrical muscle stimulation

    NASA Astrophysics Data System (ADS)

    Brennick, Michael J.; Margulies, Susan S.; Ford, John C.; Gefter, Warren B.; Pack, Allan I.

    1997-05-01

    We have developed a new and powerful method to study the movement and function of upper airway muscles. Our method is to use direct electrical stimulation of individual upper airway muscles, while performing state of the art high resolution magnetic resonance imaging (MRI). We have adapted a paralyzed isolated UA cat model so that positive or negative static pressure in the UA can be controlled at specific levels while electrical muscle stimulation is applied during MRI. With these techniques we can assess the effect of muscle stimulation on airway cross-sectional area compliance and soft tissue motion. We are reporting the preliminary results and MRI techniques which have enabled us to examine changes in airway dimensions which result form electrical stimulation of specific upper airway dilator muscles. The results of this study will be relevant to the development of new clinical treatments for obstructive sleep apnea by providing new information as to exactly how upper airway muscles function to dilate the upper airway and the strength of stimulation required to prevent the airway obstruction when overall muscle tone may not be sufficient to maintain regular breathing.

  2. Case study: a novel biomechanical approach for evaluating extended body armor systems.

    PubMed

    Selinger, Jessica C; Gooyers, Chad E; Stevenson, Joan M; Costigan, Patrick A; Chafe, Gabrielle S

    2010-11-01

    To combat the devastating effects of improvised explosive devices (IEDs), body armor that provides extended coverage has been developed. However, this extended coverage increases the armor's weight and may restrict movement. Throughout this case study, a novel technique to assess several armor systems was investigated. Four soldiers performed shoulder and trunk movements while wearing each of the six different armor inserts. Electromyography (EMG) was used to quantify muscular activity and inertial motion sensors were used to determine joint range of motion (ROM). Outcome measures included maximum ROM, integrated EMG, and the soldiers' subjective rankings. For the shoulder tasks, objective ROM and EMG measures were related to each other as well as to subjective rankings and armor material properties. Conversely, little agreement was found between measures for the trunk tasks. Results of this preliminary investigation indicate that combining shoulder ROM and EMG measures has the potential to provide an objective assessment of body armor systems.

  3. Biomechanical and histomorphometric study of dental implants with different surface characteristics.

    PubMed

    Yeo, In-Sung; Han, Jung-Suk; Yang, Jae-Ho

    2008-11-01

    The aim of this study was to investigate the early bone response to the titanium dental implants with different surface characteristics using the rabbit tibia model. Calcium metaphosphate coated, anodic oxidized, hydroxyapatite particle-blasted, and turned (control) surfaces were compared. Surface topography was evaluated by field emission scanning electron microscope and optical interferometer. Eighteen rabbits received 72 implants in the tibia. Resonance frequency was analyzed every week for 6 weeks. Removal torque values were measured 2 and 6 weeks after placement. The implant-bone interfaces were directly observed by light microscope and bone-to-implant contact ratios were measured 2 and 6 weeks after insertion. All the surface-modified implants showed superior initial bone responses to the control. No significant differences were found among the surface-modified groups. Data suggest that various surface modification methods can provide favorable bone responses for early functioning and healing of dental implants.

  4. Biomechanics of Corneal Ring Implants

    PubMed Central

    2015-01-01

    Purpose: To evaluate the biomechanics of corneal ring implants by providing a related mathematical theory and biomechanical model for the treatment of myopia and keratoconus. Methods: The spherical dome model considers the inhomogeneity of the tunica of the eye, dimensions of the cornea, lamellar structure of the corneal stroma, and asphericity of the cornea. It is used in this study for calculating a strengthening factor sf for the characterization of different ring-shaped corneal implant designs. The strengthening factor is a measure of the amount of strengthening of the cornea induced by the implant. Results: For ring segments and incomplete rings, sf = 1.0, which indicates that these implants are not able to strengthen the cornea. The intracorneal continuous complete ring (MyoRing) has a strengthening factor of up to sf = 3.2. The MyoRing is, therefore, able to strengthen the cornea significantly. Conclusions: The result of the presented biomechanical analysis of different ring-shaped corneal implant designs can explain the different postoperative clinical results of different implant types in myopia and keratoconus. PMID:26312619

  5. Patients with knee osteoarthritis demonstrate improved gait pattern and reduced pain following a non-invasive biomechanical therapy: a prospective multi-centre study on Singaporean population

    PubMed Central

    2014-01-01

    Background Previous studies have shown the effect of a unique therapy with a non-invasive biomechanical foot-worn device (AposTherapy) on Caucasian western population suffering from knee osteoarthritis. The purpose of the current study was to evaluate the effect of this therapy on the level of symptoms and gait patterns in a multi-ethnic Singaporean population suffering from knee osteoarthritis. Methods Fifty-eight patients with bilateral medial compartment knee osteoarthritis participated in the study. All patients underwent a computerized gait test and completed two self-assessment questionnaires (WOMAC and SF-36). The biomechanical device was calibrated to each patient, and therapy commenced. Changes in gait patterns and self-assessment questionnaires were reassessed after 3 and 6 months of therapy. Results A significant improvement was seen in all of the gait parameters following 6 months of therapy. Specifically, gait velocity increased by 15.9%, step length increased by 10.3%, stance phase decreased by 5.9% and single limb support phase increased by 2.7%. In addition, pain, stiffness and functional limitation significantly decreased by 68.3%, 66.7% and 75.6%, respectively. SF-36 physical score and mental score also increased significantly following 6 months of therapy (46.1% and 22.4%, respectively) (P < 0.05 for all parameters). Conclusions Singaporean population with medial compartment knee osteoarthritis demonstrated improved gait patterns, reported alleviation in symptoms and improved function and quality of life following 6 months of therapy with a unique biomechanical device. Trial registration Registration number NCT01562652. PMID:24383821

  6. The importance of accurate muscle modelling for biomechanical analyses: a case study with a lizard skull

    PubMed Central

    Gröning, Flora; Jones, Marc E. H.; Curtis, Neil; Herrel, Anthony; O'Higgins, Paul; Evans, Susan E.; Fagan, Michael J.

    2013-01-01

    Computer-based simulation techniques such as multi-body dynamics analysis are becoming increasingly popular in the field of skull mechanics. Multi-body models can be used for studying the relationships between skull architecture, muscle morphology and feeding performance. However, to be confident in the modelling results, models need to be validated against experimental data, and the effects of uncertainties or inaccuracies in the chosen model attributes need to be assessed with sensitivity analyses. Here, we compare the bite forces predicted by a multi-body model of a lizard (Tupinambis merianae) with in vivo measurements, using anatomical data collected from the same specimen. This subject-specific model predicts bite forces that are very close to the in vivo measurements and also shows a consistent increase in bite force as the bite position is moved posteriorly on the jaw. However, the model is very sensitive to changes in muscle attributes such as fibre length, intrinsic muscle strength and force orientation, with bite force predictions varying considerably when these three variables are altered. We conclude that accurate muscle measurements are crucial to building realistic multi-body models and that subject-specific data should be used whenever possible. PMID:23614944

  7. Gliding characteristics between flexor tendons and surrounding tissues in the carpal tunnel: a biomechanical cadaver study.

    PubMed

    Zhao, Chunfeng; Ettema, Anke M; Osamura, Naoki; Berglund, Lawrence J; An, Kai-Nan; Amadio, Peter C

    2007-02-01

    The purpose of this study was to investigate the gliding characteristics of flexor tendons within the carpal tunnel with varied wrist positions and tendon motion styles, which may help us to understand the relationship between carpal tunnel syndrome (CTS) and repetitive hand motion. Eight fresh human cadaveric wrists and hands were used. The peak (PGR) and mean (MGR) gliding resistance of the middle finger flexor digitorum superficialis tendon were measured with the wrist in 0, 30, and 60 degrees of flexion and extension. While moving all three fingers together, the PGR at 60 degrees flexion was significantly higher than that at 0, 30, or 60 degrees extension. While moving the middle finger alone, the PGR at 60 and 30 degrees flexion was significantly higher than the PGR at 60 degrees extension. The PGR moving the middle finger FDS alone was significantly greater than that for all three digits moving together in 0, 30, and 60 degrees flexion. Differential finger motion with wrist flexion elevated the tendon gliding resistance in the carpal tunnel, which may be relevant in considering the possible role of wrist position and activity in the etiology of CTS.

  8. Vein grafts to augment flexor tendon repairs: a biomechanical study on strength and gap resistance.

    PubMed

    Rodger, M P; Theobald, P; Giddins, G

    2015-09-01

    The ultimate tensile repair strength and gap formation of the pig extensor tendons repaired with a standard 4-strand Savage with epitendinous suture repair, was compared with a new technique of adding a vein sleeve. Force and displacement data were recorded, and video images during linear cyclic loading up to failure. At 35 N, video-graphic observation detected significantly smaller gap lengths in the standard and vein repair specimens compared with standard repair specimens (p = 0.047). The incidence of 3 mm gaps between the repaired tendon ends in the standard repair group was 20 %, but no 3 mm gaps were seen in the standard and vein specimens. The addition of a vein sleeve increased the ultimate tensile strength of the standard repair from 50.4 N (4.5) to 55.4 N (4.5); this was statistically significant (p = 0.03). This study demonstrated that the addition of a vein graft prevented gap formation and increased ultimate tensile strength of tendon repair.

  9. Zeroing of six-component handrim dynamometer for biomechanical studies of manual wheelchair locomotion.

    PubMed

    Sauret, Christophe; Dabonneville, Michel; Couétard, Yves; de Saint Rémy, Nicolas; Kauffmann, Philippe; Cid, Mariano; Vaslin, Philippe

    2014-01-01

    A six-component handrim dynamometer (HRD) is a dynamometer that rotates around the wheel axle during measurements. For this kind of dynamometer, static zero level calibration is insufficient because the proportion of the forces (i.e. handrim weight and centrifugal force) measured by each sensor varies according to the angular position and velocity of the dynamometer. The dynamic calibration presented in this paper is based on the direct correction of the sensor signals using Fourier's polynomials that take into account the influences of both the handrim weight distribution on the sensors with respect to the wheel's angular position and the effect of the wheel's angular velocity. When these corrections were applied to the signals produced by the sensors while the HRD was rotating and no effort was being exerted on the handrim, the calculated forces and torques remained close to zero, as expected. Based on these results, the wheel dynamometer can be confidently used for studying manual wheelchair locomotion under various real conditions. The method could also be applied in other situations in which a dynamometer rotates during measurements.

  10. Beam dynamics and error study of the medium energy beam transport line in the Korea Heavy-Ion Medical Accelerator

    NASA Astrophysics Data System (ADS)

    Kim, Chanmi; Kim, Eun-San; Hahn, Garam

    2016-11-01

    The Korea Heavy Ion Medical Accelerator consists of an injector and a synchrotron for an ion medical accelerator that is the first carbon-ion therapy system in Korea. The medium energy beam transport(MEBT) line connects the interdigital H-mode drift tube linac and the synchrotron. We investigated the beam conditions after the charge stripper by using the LISE++ and the SRIM codes. The beam was stripped from C4+ into C6+ by using the charge stripper. We investigated the performance of a de-buncher in optimizing the energy spread and the beam distribution in z-dW/W (direction of beam progress-beam and energy) phase. We obtained the results of the tracking simulation and the error analysis by using the TRACK code. Possible misalignments and rotations of the magnets were considered in the simulations. States of the beam were examined when errors occurred in the magnets by the applying analytic fringe field model in TRACK code. The condition for the beam orbit was optimized by using correctors and profile monitors to correct the orbit. In this paper, we focus on the beam dynamics and the error studies dedicated to the MEBT beam line and show the optimized beam parameters for the MEBT.

  11. The use of biomechanics in the study of movement in microgravity

    NASA Technical Reports Server (NTRS)

    Gregor, R. J.; Broker, J. P.; Ryan, M. M.

    1994-01-01

    As biomechanists interested in the adaptability of the human body to microgravity conditions, it appears that our job is not only to make sure that the astronauts can function adequately in space but also that they can function upon their return to Earth. This is especially significant since many of the projects now being designed at NASA concern themselves with humans performing for up to 3 years in microgravity. While the Extended Duration Orbiter flights may last 30 to 60 days, future flights to Mars using current propulsion technology may last from 2 to 3 years. It is for this range of time that the adaptation process must be studied. Specifically, biomechanists interested in space travel realize that human performance capabilities will change as a result of exposure to microgravity. The role of the biomechanist then is to first understand the nature of the changes realized by the body. These changes include adaptation by the musculoskeletal system, the nervous system, cardiorespiratory system, and the cardiovascular system. As biomechanists, it is also our role to take part in the development of countermeasure programs that involve some form of regular exercise. Exercise countermeasure programs should include a variety of modalities with full knowledge of the loads imposed on the body by these modalities. Any exercise programs that are to be conducted by the astronauts during space travel must consider the fact that the musculoskeletal and neuromuscular systems degrade as a function of flight duration. Additionally, it must be understood that the central nervous system modifies its output in the control of the human body during space flight and most importantly, we must prepare the astronauts for their return to one g.

  12. A biomechanical study of two different pedicle screw methods for fixation in osteoporotic and nonosteoporotic vertebrae.

    PubMed

    Higashino, Kosaku; Kim, Jin Hwan; Horton, William C; Hutton, William C

    2012-01-01

    In reconstruction of the osteoporotic spine, patients often show poor outcome because of pedicle screw failure. This study used osteoporotic and nonosteoporotic vertebrae to determine the difference in fixation strength between pedicle screws inserted straight forward and pedicle screws inserted in an upward trajectory toward the superior end plate (i.e., end-plate screws). There is some evidence to suggest that end-plate screws have a strength advantage. The particular focus was on osteoporotic vertebrae. Thirty-three vertebrae (T10-L2) were harvested. The bone mineral density (BMD) was measured: 15 vertebrae were greater than 0.8 g/cm(2) and designated as nonosteoporotic (average BMD 1.146 ± 0.186 g/cm(2)) and 18 vertebrae were designated as osteoporotic (average BMD 0.643 ± 0.088 g/cm(2)). On one pedicle the screw was inserted straight forward and on the other pedicle the screw was inserted as an end-plate screw. The torque of insertion was measured (Proto 6106 torque screwdriver). Using an MTS Mini Bionix, two types of mechanical testing were carried out on each pedicle: (a) cephalocaudad toggling was first carried out to simulate some physiological type loading: 500 cycles at 0.3 Hz, at ±50 N; and (b) then each pedicle screw was pulled out at a displacement rate of 12.5 cm/min.There was no difference in pullout force between the pedicle screws inserted straight forward and the pedicle screws inserted as end-plate screws. This result applies whether the vertebrae were osteoporotic or nonosteoporotic. For both the straight-forward screws and the end-plate screws, a statistically significant correlation was observed between torque of insertion and pullout force. The results of this experiment indicate that pedicle screws inserted as end-plate screws do not provide a strength advantage over pedicle screws inserted straight forward, whether the vertebrae are osteoporotic or not.

  13. Fracture resistance of orthodontic mini-implants: a biomechanical in vitro study.

    PubMed

    Wilmes, Benedict; Panayotidis, Agamemnon; Drescher, Dieter

    2011-08-01

    Sufficient primary stability is of importance for the survival of orthodontic mini-implants. This means that adequate torque has to be achieved during insertion. However, as moments exceeding the fracture resistance of a mini-implant may result in their fracture, the maximum torque load capacity should be known. In this study, the threshold torque values resulting in the fracture of various mini-implant types and diameters were evaluated. Forty-one different mini-implants with diameters ranging from 1.3 to 2.0 mm (Aarhus screw, Abso Anchor, Ancora, Bone screw, Dual Top, Lomas, MAS, O.S.A.S, Ortho Easy, Spider Screw, and Tomas pin) were inserted in acrylic glass by a robot system. Ten specimens of each mini-implant type were tested. The insertion torque was measured and the maximum torque at the time of mini-implant fracture was evaluated. Significance of the mean value differences was evaluated by Kruskal-Wallis tests. Fracture moments varied depending on the diameter of the mini-implants. The measured values ranged from 108.9 Nmm (MAS 1.3×11 mm) to 640.9 Nmm (Lomas 2.0×11 mm). The differences were highly statistically significant (P<0.001). The risk of mini-implant fracture should be borne in mind at the time of insertion, especially if mini-implants with a small diameter are employed. To minimize the risk of fracture, pre-drilling should be carried out if the mini-implants are to be inserted at a site with a high bone density.

  14. SU-E-T-635: Quantitative Study On Beam Flatness Variation with Beam Energy Change

    SciTech Connect

    Li, J S; Eldib, A; Ma, C; Lin, M

    2014-06-15

    Purpose: Beam flatness check has been proposed for beam energy check for photon beams with flattering filters. In this work, beam flatness change with beam energy was investigated quantitatively using the Monte Carlo method and its significance was compared with depth dose curve change. Methods: Monte Carlo simulations for a linear accelerator with flattering filter were performed with different initial electron energies for photon beams of 6MV and 10MV. Dose calculations in a water phantom were then perform with the phase space files obtained from the simulations. The beam flatness was calculated based on the dose profile at 10 cm depth for all the beams with different initial electron energies. The percentage depth dose (PDD) curves were also analyzed. The dose at 10cm depth (D10) and the ratio of the dose at 10cm and 20cm depth (D10/D20) and their change with the beam energy were calculated and compared with the beam flatness variation. Results: It was found that the beam flatness variation with beam energy change was more significant than the change of D10 and the ratio between D10 and D20 for both 6MV and 10MV beams. Half MeV difference on the initial electron beam energy brought in at least 20% variation on the beam flatness but only half percent change on the ratio of D10 and D20. The change of D10 or D20 alone is even less significant. Conclusion: The beam energy impact on PDD is less significant than that on the beam flatness. If the PDD is used for checking the beam energy, uncertainties of the measurement could possibly disguise its change. Beam flatness changes more significantly with beam energy and therefore it can be used for monitoring the energy change for photon beams with flattering filters. However, other factors which may affect the beam flatness should be watched as well.

  15. A Biomechanical Stability Study of Extraforaminal Lumbar Interbody Fusion on the Cadaveric Lumbar Spine Specimens

    PubMed Central

    Guo, Song; Yan, Meijun; Han, Yingchao; Xia, Dongdong; Sun, Guixin; Li, Lijun; Tan, Jun

    2016-01-01

    Background Transforaminal lumbar interbody fusion (TLIF) is an effective surgery for lumbar degenerative disease. However, this fusion technique requires resection of inferior facet joint to provide access for superior facet joint resection, which results in reduced lumbar spinal stability and unnecessary trauma. We have previously developed extraforaminal lumbar interbody fusion (ELIF) that can avoid back muscle injury with direct nerve root decompression. This study aims to show that ELIF enhances lumbar spinal stability in comparison to TLIF by comparing lumbar spinal stability of L4–L5 range of motion (ROM) on 12 cadaveric spine specimens after performing TLIF or ELIF. Methods 12 cadaveric spine specimens were randomly divided and treated in accordance with the different internal fixations, including ELIF with a unilateral pedicle screw (ELIF+UPS), TLIF with a unilateral pedicle screw (TLIF+UPS), TLIF with a bilateral pedicle screw (TLIF+BPS), ELIF with a unilateral pedicle screw and translaminar facet screw (ELIF+UPS+TLFS) and ELIF with a bilateral pedicle screw (ELIF+BPS). The treatment groups were exposed to a 400-N load and 6 N·m movement force to calculate the angular displacement of L4-L5 during anterior flexion, posterior extension, lateral flexion and rotation operation conditions. Results The ROM in ELIF+UPS group was smaller than that of TLIF+UPS group under all operating conditions, with the significant differences in left lateral flexion and right rotation by 36.15% and 25.97% respectively. The ROM in ELIF+UPS group was higher than that in TLIF+BPS group. The ROM in the ELIF+UPS+TLFS group was much smaller than that in the ELIF+UPS group, but was not significantly different than that in the TLIF+BPS group. Conclusions Despite that TLIF+BPS has great stability, which can be comparable by that of ELIF+UPS. Additionally, ELIF stability can be further improved by using translaminar facet screws without causing more tissue damage to patient. PMID

  16. Biomechanical Study of the Fixation Strength of Anteromedial Plating for Humeral Shaft Fractures

    PubMed Central

    Zheng, Yin-Feng; Zhou, Jun-Lin; Wang, Xiao-Hong; Shan, Lei; Liu, Yang

    2016-01-01

    Background: Open reduction and internal fixation with plate and screws are the gold standard for the surgical treatment of humeral shaft fractures, this study was to compare the mechanical properties of anteromedial, anterolateral, and posterior plating for humeral shaft fractures. Methods: A distal third humeral shaft fracture model was constructed using fourth-generation sawbones (#3404, composite bone). A total of 24 sawbones with a distal third humeral shaft fracture was randomly divided into three Groups: A, B, and C (n = 8 in each group) for anteromedial, anterolateral, and posterior plating, respectively. All sawbones were subjected to horizontal torsional fatigue tests, horizontal torsional and axial compressive fatigue tests, four-point bending fatigue tests in anteroposterior (AP) and mediolateral (ML) directions and horizontal torsional destructive tests. Results: In the horizontal torsional fatigue tests, the mean torsional angle amplitude in Groups A, B, and C were 6.12°, 6.53°, and 6.81°. In horizontal torsional and axial compressive fatigue tests, the mean torsional angle amplitude in Groups A, B, and C were 5.66°, 5.67°, and 6.36°. The mean plate displacement amplitude was 0.05 mm, 0.08 mm, and 0.10 mm. Group A was smaller than Group C (P < 0.05). In AP four-point bending fatigue tests, the mean plate displacement amplitude was 0.16 mm, 0.13 mm, and 0.20 mm. Group B was smaller than Group C (P < 0.05). In ML four-point bending fatigue tests, the mean plate displacement amplitude were 0.16 mm, 0.19 mm, and 0.17 mm. In horizontal torsional destructive tests, the mean torsional rigidity in Groups A, B, and C was 0.82, 0.75, and 0.76 N·m/deg. The yielding torsional angle was 24.50°, 25.70°, and 23.86°. The mean yielding torque was 18.46, 18.05, and 16.83 N·m, respectively. Conclusions: Anteromedial plating was superior to anterolateral or posterior plating in all mechanical tests except in AP four-point bending fatigue tests compared to the

  17. Compression and contact area of anterior strut grafts in spinal instrumentation: a biomechanical study

    PubMed Central

    2013-01-01

    Background Anterior bone grafts are used as struts to reconstruct the anterior column of the spine in kyphosis or following injury. An incomplete fusion can lead to later correction losses and compromise further healing. Despite the different stabilizing techniques that have evolved, from posterior or anterior fixating implants to combined anterior/posterior instrumentation, graft pseudarthrosis rates remain an important concern. Furthermore, the need for additional anterior implant fixation is still controversial. In this bench-top study, we focused on the graft-bone interface under various conditions, using two simulated spinal injury models and common surgical fixation techniques to investigate the effect of implant-mediated compression and contact on the anterior graft. Methods Calf spines were stabilised with posterior internal fixators. The wooden blocks as substitutes for strut grafts were impacted using a “pressfit” technique and pressure-sensitive films placed at the interface between the vertebral bone and the graft to record the compression force and the contact area with various stabilization techniques. Compression was achieved either with posterior internal fixator alone or with an additional anterior implant. The importance of concomitant ligament damage was also considered using two simulated injury models: pure compression Magerl/AO fracture type A or rotation/translation fracture type C models. Results In type A injury models, 1 mm-oversized grafts for impaction grafting provided good compression and fair contact areas that were both markedly increased by the use of additional compressing anterior rods or by shortening the posterior fixator construct. Anterior instrumentation by itself had similar effects. For type C injuries, dramatic differences were observed between the techniques, as there was a net decrease in compression and an inadequate contact on the graft occurred in this model. Under these circumstances, both compression and the

  18. Biomechanics, Exercise Physiology, and the 75th Anniversary of RQES

    ERIC Educational Resources Information Center

    Hamill, Joseph; Haymes, Emily M.

    2005-01-01

    The purpose of this paper is to review the biomechanics and exercise physiology studies published in the Research Quarterly for Exercise and Sport (RQES) over the past 75 years. Studies in biomechanics, a relatively new subdiscipline that evolved from kinesiology, first appeared in the journal about 40 years ago. Exercise physiology studies have…

  19. Study of longitudinal dynamics in space-charge dominated beams

    NASA Astrophysics Data System (ADS)

    Tian, Kai

    from the 6-D phase space measurement has been used as initial conditions in computer simulations in order to explore the cause of discrepancies we have observed earlier between the experimental and theoretical models. After extensive simulation studies, we find that the beam loss inside the perturbation due to mismatch or misalignment is an important factor that needs to be included in the models for better reliability.

  20. Corneal biomechanics: a review.

    PubMed

    Piñero, David P; Alcón, Natividad

    2015-03-01

    Biomechanics is often defined as 'mechanics applied to biology'. Due to the variety and complexity of the behaviour of biological structures and materials, biomechanics is better defined as the development, extension and application of mechanics for a better understanding of physiology and physiopathology and consequently for a better diagnosis and treatment of disease and injury. Different methods for the characterisation of corneal biomechanics are reviewed in detail, including those that are currently commercially available (Ocular Response Analyzer and CorVis ST). The clinical applicability of the parameters provided by these devices are discussed, especially in the fields of glaucoma, detection of ectatic disorders and orthokeratology. Likewise, other methods are also reviewed, such as Brillouin microscopy or dynamic optical coherence tomography and others with potential application to clinical practice but not validated for in vivo measurements, such as ultrasonic elastography. Advantages and disadvantages of all these techniques are described. Finally, the concept of biomechanical modelling is revised as well as the requirements for developing biomechanical models, with special emphasis on finite element modelling.

  1. Biomechanics of concussion.

    PubMed

    Stemper, Brian D; Pintar, Frank A

    2014-01-01

    This report provides an overview of the biomechanics associated with mild traumatic brain injury (TBI), also known as concussion. Specifically, the role of angular acceleration in modulating concussion onset and severity is highlighted. Studies conducted and published from the 1960s to the 1980s provided initial estimates for TBI tolerance due to high rate head rotation. However, injury levels in those studies were more severe than what is considered to be concussion in the contemporary environment. Therefore, this issue deserves additional attention to provide quantitative estimates for concussive tolerance due to head rotational acceleration focusing on the types of clinical outcomes described today. Likewise, concussion in military personnel has notably increased in current conflicts due to the incorporation of improvised explosive devices and roadside bombs. Clinical evidence indicates that outcomes from concussion due to blast may be quite different from those due to head rotational acceleration. This report also provides an overview of blast concussion mechanisms and highlights some of the recent preclinical work in this area. As with head rotational acceleration, blast tolerance is necessary to understand the scope of this problem, better protect these personnel, and provide more informed return-to-duty guidelines for service members.

  2. The effect of the variation in ACL constitutive model on joint kinematics and biomechanics under different loads: a finite element study.

    PubMed

    Wan, Chao; Hao, Zhixiu; Wen, Shizhu

    2013-04-01

    The biomechanics and function of the anterior cruciate ligament (ACL) have been widely studied using both experimental and simulation methods. It is known that a constitutive model of joint tissue is a critical factor in the numerical simulation. Some different ligament constitutive models have been presented to describe the ACL material behavior. However, the effect of the variation in the ligament constitutive model on joint kinematics and biomechanics has still not been studied. In this paper, a three-dimensional finite element model of an intact tibiofemoral joint was reconstructed. Three ACL constitutive models were compared under different joint loads (such as anterior tibial force, varus tibial torque, and valgus tibial torque) to investigate the effect of the change of the ACL constitutive model. The three constitutive models corresponded to an isotropic hyperelasticity model, a transversely isotropic hyperelasticity model with neo-Hookean ground substance description, and a transversely isotropic hyperelastic model with nonlinear ground substance description. Although the material properties of these constitutive equations were fitted on the same uniaxial tension stress-strain curve, the change of the ACL material constitutive model was found to induce altered joint kinematics and biomechanics. The effect of different ACL constitutive equations on joint kinematics depended on both deformation direction and load type. The variation in the ACL constitutive models would influence the joint kinematic results greatly in both the anterior and internal directions under anterior tibial force as well as some other deformations such as the anterior and medial tibial translations under valgus tibial torque, and the medial tibial translation and internal rotation under varus torque. It was revealed that the transversely isotropic hyperelastic model with nonlinear ground substance description (FE model III) was the best representation of the realistic ACL property by a

  3. Factors Related to Students' Learning of Biomechanics Concepts

    ERIC Educational Resources Information Center

    Hsieh, ChengTu; Smith, Jeremy D.; Bohne, Michael; Knudson, Duane

    2012-01-01

    The purpose of this study was to replicate and expand a previous study to identify the factors that affect students' learning of biomechanical concepts. Students were recruited from three universities (N = 149) located in the central and western regions of the United States. Data from 142 students completing the Biomechanics Concept Inventory…

  4. A Case Study in Proton Pencil-Beam Scanning Delivery

    SciTech Connect

    Kooy, Hanne M.; Clasie, Benjamin M.; Lu, H.-M.; Madden, Thomas M.; Bentefour, Hassan; Depauw, Nicolas M.S.; Adams, Judy A.; Trofimov, Alexei V.; Demaret, Denis; Delaney, Thomas F.; Flanz, Jacob B.

    2010-02-01

    Purpose: We completed an implementation of pencil-beam scanning (PBS), a technology whereby a focused beam of protons, of variable intensity and energy, is scanned over a plane perpendicular to the beam axis and in depth. The aim of radiotherapy is to improve the target to healthy tissue dose differential. We illustrate how PBS achieves this aim in a patient with a bulky tumor. Methods and Materials: Our first deployment of PBS uses 'broad' pencil-beams ranging from 20 to 35 mm (full-width-half-maximum) over the range interval from 32 to 7 g/cm{sup 2}. Such beam-brushes offer a unique opportunity for treating bulky tumors. We present a case study of a large (4,295 cc clinical target volume) retroperitoneal sarcoma treated to 50.4 Gy relative biological effectiveness (RBE) (presurgery) using a course of photons and protons to the clinical target volume and a course of protons to the gross target volume. Results: We describe our system and present the dosimetry for all courses and provide an interdosimetric comparison. Discussion: The use of PBS for bulky targets reduces the complexity of treatment planning and delivery compared with collimated proton fields. In addition, PBS obviates, especially for cases as presented here, the significant cost incurred in the construction of field-specific hardware. PBS offers improved dose distributions, reduced treatment time, and reduced cost of treatment.

  5. Fermilab Booster Transition Crossing Simulations and Beam Studies

    SciTech Connect

    Bhat, C. M.; Tan, C. Y.

    2016-01-01

    The Fermilab Booster accelerates beam from 400 MeV to 8 GeV at 15 Hz. In the PIP (Proton Improvement Plan) era, it is required that Booster deliver 4.2 x $10^{12}$ protons per pulse to extraction. One of the obstacles for providing quality beam to the users is the longitudinal quadrupole oscillation that the beam suffers from right after transition. Although this oscillation is well taken care of with quadrupole dampers, it is important to understand the source of these oscillations in light of the PIP II requirements that require 6.5 x $10^{12}$ protons per pulse at extraction. This paper explores the results from machine studies, computer simulations and solutions to prevent the quadrupole oscillations after transition.

  6. Spheromak Energy Transport Studies via Neutral Beam Injection

    SciTech Connect

    McLean, H S; Hill, D N; Wood, R D; Jayakumar, J; Pearlstein, L D

    2008-02-11

    Results from the SSPX spheromak experiment provide strong motivation to add neutral beam injection (NBI) heating. Such auxiliary heating would significantly advance the capability to study the physics of energy transport and pressure limits for the spheromak. This LDRD project develops the physics basis for using NBI to heat spheromak plasmas in SSPX. The work encompasses three activities: (1) numerical simulation to make quantitative predictions of the effect of adding beams to SSPX, (2) using the SSPX spheromak and theory/modeling to develop potential target plasmas suitable for future application of neutral beam heating, and (3) developing diagnostics to provide the measurements needed for transport calculations. These activities are reported in several publications.

  7. High Brightness Electron Beam Studies at the NSLS SDL

    SciTech Connect

    Qian,H.; Hidaka, Y.; Murphy, J. B.; Podobedov, B.; Seletskiy, S.; Shen, Y.; Yang, X.; Wang, X. J.; Tang, C. X.

    2009-05-04

    Experimental optimization of electron beam brightness at the NSLS SDL is reported in this paper. Using a high quantum efficiency (QE) Mg metal cathode and the S-band BNL-type RF gun, we have systematically studied electron beams transverse and longitudinal emittance. The measured thermal emittance for the Mg cathode is 0.85{+-}0.04 mm-mrad/mm, which contradicts the current thermal emittance model. For a 50 pC beam, measured normalized transverse and longitudinal RMS emittance are 0.6 mm-mrd and 5.2 ps-keV, respectively. The smallest projected transverse emittance observed for a 20 pC charge is 0.15 {+-} 0.02 mm-mrad.

  8. Studies of polarized beam acceleration and Siberian Snakes

    SciTech Connect

    Lee, S.Y.

    1992-12-31

    We studied depolarization mechanisms of polarized proton acceleration in high energy accelerators with snakes and found that the perturbed spin tune due to the imperfection resonance plays an important role in beam depolarization at snake resonances. We also found that even order snake resonances exist in the overlapping intrinsic and imperfection resonances. Due to the perturbed spin tune of imperfection resonances, each snake resonance splits into two. Thus the available betatron tune space becomes smaller. Some constraints on polarized beam colliders were also examined.

  9. Molecular Beam Studies of Low Energy Reactions.

    DTIC Science & Technology

    1983-03-31

    COMPLETING PORN . REPORT NUMBER 1 2. GOVT ACCESSION NO. S. RECIPIENT’S CATALOG NUMBER A D A Oaq J- 4. TITLE (And Subtitle) . TYPE OF REPORT & PERIOD COVERED...Gatlinburg, Tenn . in 1981. 2+ c) Studies were made of the charge transfer reaction Ar + Ar 4 2+ Ar + Ar at relative energies from 2 to 1000 eV. Reasons for

  10. Simulation study of dynamic aperture with head-on beam-beam compensation in the RHIC

    SciTech Connect

    Luo, Y.; Fischer, W.

    2010-08-01

    In this note we summarize the calculated 10{sup 6} turn dynamic apertures with the proposed head-on beam-beam compensation in the Relativistic Heavy Ion Collider (RHIC). To compensate the head-on beam-beam effect in the RHIC 250 GeV polarized proton run, we are planning to introduce a DC electron beam with the same transverse profile as the proton beam to collide with the proton beam. Such a device to provide the electron beam is called an electron lens (e-lens). In this note we first present the optics and beam parameters and the tracking setup. Then we compare the calculated dynamic apertures without and with head-on beam-beam compensation. The effects of adjusted phase advances between IP8 and the center of e-lens and second order chromaticity correction are checked. In the end we will scan the proton and electron beam parameters with head-on beam-beam compensation.

  11. Cluster Beam Studies of Metal Combustion

    DTIC Science & Technology

    1992-07-21

    begun the first high-quality experiments on reactions of clean boron surfaces. This work is important because it directly measures the elementary...studies. (See Fig. 1 for a schematic diagram of one of the instruments). * Measurements of reaction cross sections over a wide collision energy range... Measurement of exciton structure near the boron K-edge. * High level ab iniflo calculation of boron duster ion structures and properties to compliment

  12. A preliminary case study of the effect of shoe-wearing on the biomechanics of a horse’s foot

    PubMed Central

    Rankin, Jeffery W.; Gatesy, Stephen M.

    2016-01-01

    Horse racing is a multi-billion-dollar industry that has raised welfare concerns due to injured and euthanized animals. Whilst the cause of musculoskeletal injuries that lead to horse morbidity and mortality is multifactorial, pre-existing pathologies, increased speeds and substrate of the racecourse are likely contributors to foot disease. Horse hooves have the ability to naturally deform during locomotion and dissipate locomotor stresses, yet farriery approaches are utilised to increase performance and protect hooves from wear. Previous studies have assessed the effect of different shoe designs on locomotor performance; however, no biomechanical study has hitherto measured the effect of horseshoes on the stresses of the foot skeleton in vivo. This preliminary study introduces a novel methodology combining three-dimensional data from biplanar radiography with inverse dynamics methods and finite element analysis (FEA) to evaluate the effect of a stainless steel shoe on the function of a Thoroughbred horse’s forefoot during walking. Our preliminary results suggest that the stainless steel shoe shifts craniocaudal, mediolateral and vertical GRFs at mid-stance. We document a similar pattern of flexion-extension in the PIP (pastern) and DIP (coffin) joints between the unshod and shod conditions, with slight variation in rotation angles throughout the stance phase. For both conditions, the PIP and DIP joints begin in a flexed posture and extend over the entire stance phase. At mid-stance, small differences in joint angle are observed in the PIP joint, with the shod condition being more extended than the unshod horse, whereas the DIP joint is extended more in the unshod than the shod condition. We also document that the DIP joint extends more than the PIP after mid-stance and until the end of the stance in both conditions. Our FEA analysis, conducted solely on the bones, shows increased von Mises and Maximum principal stresses on the forefoot phalanges in the shod

  13. Student factors related to learning in biomechanics.

    PubMed

    Hsieh, Chengtu; Knudson, Duane

    2008-09-01

    The aim of this study was to identify the student behaviours and characteristics that are related to learning biomechanical concepts. The Biomechanics Concept Inventory (BCI) was given to 53 kinesiology majors before and after an introductory biomechanics class together with a survey of student behaviours to determine factors that assisted in learning. Analysis of scores from 49 students showed significant (P < 0.001) improvement following instruction. Variables that significantly (P < 0.05) and uniquely correlated with improvement were grade point average (r = 0.46) and student interest in biomechanics (r = 0.41). Thirty-one percent of the variance in learning could be accounted for by these two variables, with no distinctive associations with student behaviours like course reading, hours studying, and credits earned in maths and physics. However, grade point average was significantly correlated with several student behaviour variables. Consequently, student learning of biomechanical concepts is likely a complex phenomenon with individual learning related to variables that interact with student interest and overall academic ability.

  14. Commisioning of the second Tevatron electron lens and beam study results

    SciTech Connect

    Kamerdzhiev, V.; Fellenz, B.; Hively, R.; Kuznetsov, G.; Olson, M.; Pfeffer, H.; Saewert, G.; Scarpine, V.; Shiltsev, V.; Zhang, X.L.; /Fermilab

    2007-06-01

    In the framework of Fermilab's Beam-Beam Compensation (BBC) project, the 2nd Tevatron Electron Lens (TEL2) was installed in the Tevatron during Spring 2006 shutdown. It was successfully commissioned and a series of beam studies has been carried out in single bunch and all-bunch modes. The paper describes TEL2 commissioning and beam studies results.

  15. Parametric study of beam refraction problems across laser anemometer windows

    NASA Technical Reports Server (NTRS)

    Owen, A. K.

    1986-01-01

    The experimenter is often required to view flows through a window with a different index of refraction than either the medium being observed or the medium that the laser anemometer is immersed in. The refraction that occurs at the window surfaces may lead to undesirable changes in probe volume position or beam crossing angle and can lead to partial or complete beam uncrossing. This report describes the results of a parametric study of this problem using a ray tracing technique to predict these changes. The windows studied were a flat plate and a simple cyclinder. For the flat-plate study: (1) surface thickness, (2) beam crossing angle, (3) bisecting line - surface normal angle, and (4) incoming beam plane surface orientation were varied. For the cylindrical window additional parameters were also varied: (1) probe volume immersion, (2) probe volume off-radial position, and (3) probe volume position out of the R-theta plane of the lens. A number of empirical correlations were deduced to aid the interested reader in determining the movement, uncrossing, and change in crossing angle for a particular situation.

  16. Study of a multi-beam accelerator driven thorium reactor

    SciTech Connect

    Ludewig, H.; Aronson, A.

    2011-03-01

    The primary advantages that accelerator driven systems have over critical reactors are: (1) Greater flexibility regarding the composition and placement of fissile, fertile, or fission product waste within the blanket surrounding the target, and (2) Potentially enhanced safety brought about by operating at a sufficiently low value of the multiplication factor to preclude reactivity induced events. The control of the power production can be achieved by vary the accelerator beam current. Furthermore, once the beam is shut off the system shuts down. The primary difference between the operation of an accelerator driven system and a critical system is the issue of beam interruptions of the accelerator. These beam interruptions impose thermo-mechanical loads on the fuel and mechanical components not found in critical systems. Studies have been performed to estimate an acceptable number of trips, and the value is significantly less stringent than had been previously estimated. The number of acceptable beam interruptions is a function of the length of the interruption and the mission of the system. Thus, for demonstration type systems and interruption durations of 1sec < t < 5mins, and t > 5mins 2500/yr and 50/yr are deemed acceptable. However, for industrial scale power generation without energy storage type systems and interruption durations of t < 1sec., 1sec < t < 10secs., 10secs < t < 5mins, and t > 5mins, the acceptable number of interruptions are 25000, 2500, 250, and 3 respectively. However, it has also been concluded that further development is required to reduce the number of trips. It is with this in mind that the following study was undertaken. The primary focus of this study will be the merit of a multi-beam target system, which allows for multiple spallation sources within the target/blanket assembly. In this manner it is possible to ameliorate the effects of sudden accelerator beam interruption on the surrounding reactor, since the remaining beams will still

  17. Fast beam studies of free radical photodissociation

    SciTech Connect

    Cyr, Douglas Robert

    1993-11-01

    The photodissociation of free radicals is studied in order to characterize the spectroscopy and dissociation dynamics of the dissociative electronic states in these species. To accomplish this, a novel method of radical production, based on the photodetachment of the corresponding negative ion, has been combined with a highly complementary form of photofragment translational spectroscopy. The optical spectroscopy of transitions to dissociative states is determined by monitoring the total photofragment yield as a function of dissociation photon energy. Branching ratios to various product channels, internal energy distributions of the fragments, bond dissociation energies, and the translational energy-dependent photofragment recoil angular distributions are then determined at selected excitation energies. A detailed picture of the dissociation dynamics can then be formulated, allowing insight concerning the interactions of potential energy surfaces involved in the dissociation. After an introduction to the concepts and techniques mentioned above, the experimental apparatus used in these experiments is described in detail. The basis and methods used in the treatment of data, especially in the dissociation dynamics experiments, are then put forward.

  18. Modeling the impact of prostate edema on LDR brachytherapy: a Monte Carlo dosimetry study based on a 3D biphasic finite element biomechanical model

    NASA Astrophysics Data System (ADS)

    Mountris, K. A.; Bert, J.; Noailly, J.; Rodriguez Aguilera, A.; Valeri, A.; Pradier, O.; Schick, U.; Promayon, E.; Gonzalez Ballester, M. A.; Troccaz, J.; Visvikis, D.

    2017-03-01

    Prostate volume changes due to edema occurrence during transperineal permanent brachytherapy should be taken under consideration to ensure optimal dose delivery. Available edema models, based on prostate volume observations, face several limitations. Therefore, patient-specific models need to be developed to accurately account for the impact of edema. In this study we present a biomechanical model developed to reproduce edema resolution patterns documented in the literature. Using the biphasic mixture theory and finite element analysis, the proposed model takes into consideration the mechanical properties of the pubic area tissues in the evolution of prostate edema. The model’s computed deformations are incorporated in a Monte Carlo simulation to investigate their effect on post-operative dosimetry. The comparison of Day1 and Day30 dosimetry results demonstrates the capability of the proposed model for patient-specific dosimetry improvements, considering the edema dynamics. The proposed model shows excellent ability to reproduce previously described edema resolution patterns and was validated based on previous findings. According to our results, for a prostate volume increase of 10–20% the Day30 urethra D10 dose metric is higher by 4.2%–10.5% compared to the Day1 value. The introduction of the edema dynamics in Day30 dosimetry shows a significant global dose overestimation identified on the conventional static Day30 dosimetry. In conclusion, the proposed edema biomechanical model can improve the treatment planning of transperineal permanent brachytherapy accounting for post-implant dose alterations during the planning procedure.

  19. Biomechanics and mechanobiology in functional tissue engineering

    PubMed Central

    Guilak, Farshid; Butler, David L.; Goldstein, Steven A.; Baaijens, Frank P.T.

    2014-01-01

    The field of tissue engineering continues to expand and mature, and several products are now in clinical use, with numerous other preclinical and clinical studies underway. However, specific challenges still remain in the repair or regeneration of tissues that serve a predominantly biomechanical function. Furthermore, it is now clear that mechanobiological interactions between cells and scaffolds can critically influence cell behavior, even in tissues and organs that do not serve an overt biomechanical role. Over the past decade, the field of “functional tissue engineering” has grown as a subfield of tissue engineering to address the challenges and questions on the role of biomechanics and mechanobiology in tissue engineering. Originally posed as a set of principles and guidelines for engineering of load-bearing tissues, functional tissue engineering has grown to encompass several related areas that have proven to have important implications for tissue repair and regeneration. These topics include measurement and modeling of the in vivo biomechanical environment; quantitative analysis of the mechanical properties of native tissues, scaffolds, and repair tissues; development of rationale criteria for the design and assessment of engineered tissues; investigation of the effects biomechanical factors on native and repair tissues, in vivo and in vitro; and development and application of computational models of tissue growth and remodeling. Here we further expand this paradigm and provide examples of the numerous advances in the field over the past decade. Consideration of these principles in the design process will hopefully improve the safety, efficacy, and overall success of engineered tissue replacements. PMID:24818797

  20. Biomechanics and mechanobiology in functional tissue engineering.

    PubMed

    Guilak, Farshid; Butler, David L; Goldstein, Steven A; Baaijens, Frank P T

    2014-06-27

    The field of tissue engineering continues to expand and mature, and several products are now in clinical use, with numerous other preclinical and clinical studies underway. However, specific challenges still remain in the repair or regeneration of tissues that serve a predominantly biomechanical function. Furthermore, it is now clear that mechanobiological interactions between cells and scaffolds can critically influence cell behavior, even in tissues and organs that do not serve an overt biomechanical role. Over the past decade, the field of "functional tissue engineering" has grown as a subfield of tissue engineering to address the challenges and questions on the role of biomechanics and mechanobiology in tissue engineering. Originally posed as a set of principles and guidelines for engineering of load-bearing tissues, functional tissue engineering has grown to encompass several related areas that have proven to have important implications for tissue repair and regeneration. These topics include measurement and modeling of the in vivo biomechanical environment; quantitative analysis of the mechanical properties of native tissues, scaffolds, and repair tissues; development of rationale criteria for the design and assessment of engineered tissues; investigation of the effects biomechanical factors on native and repair tissues, in vivo and in vitro; and development and application of computational models of tissue growth and remodeling. Here we further expand this paradigm and provide examples of the numerous advances in the field over the past decade. Consideration of these principles in the design process will hopefully improve the safety, efficacy, and overall success of engineered tissue replacements.

  1. Biomechanics of foetal movement.

    PubMed

    Nowlan, N C

    2015-01-02

    Foetal movements commence at seven weeks of gestation, with the foetal movement repertoire including twitches, whole body movements, stretches, isolated limb movements, breathing movements, head and neck movements, jaw movements (including yawning, sucking and swallowing) and hiccups by ten weeks of gestational age. There are two key biomechanical aspects to gross foetal movements; the first being that the foetus moves in a dynamically changing constrained physical environment in which the freedom to move becomes increasingly restricted with increasing foetal size and decreasing amniotic fluid. Therefore, the mechanical environment experienced by the foetus affects its ability to move freely. Secondly, the mechanical forces induced by foetal movements are crucial for normal skeletal development, as evidenced by a number of conditions and syndromes for which reduced or abnormal foetal movements are implicated, such as developmental dysplasia of the hip, arthrogryposis and foetal akinesia deformation sequence. This review examines both the biomechanical effects of the physical environment on foetal movements through discussion of intrauterine factors, such as space, foetal positioning and volume of amniotic fluid, and the biomechanical role of gross foetal movements in human skeletal development through investigation of the effects of abnormal movement on the bones and joints. This review also highlights computational simulations of foetal movements that attempt to determine the mechanical forces acting on the foetus as it moves. Finally, avenues for future research into foetal movement biomechanics are highlighted, which have potential impact for a diverse range of fields including foetal medicine, musculoskeletal disorders and tissue engineering.

  2. A positron beam study on vacancy formation in iron by ion beam irradiation at low temperature

    NASA Astrophysics Data System (ADS)

    Iwai, T.; Murakami, K.; Katano, Y.; Iwata, T.; Onitsuka, T.; Abe, H.

    2010-04-01

    This study intends to investigate cascade damage structure produced by energetic ion irradiation. Cascade damage structure is preserved at low temperature below stage I where interstitial atoms begin to migrate. Then positron beam is implanted to the irradiated surface as a vacancy probe to evaluate vacancy concentration remained in the irradiated specimens. By this method, defect production efficiency was evaluated for iron irradiated with proton and carbon ions. The defect production efficiency values indicate enhanced recombination for carbon irradiation due to primary knock-on atoms (PKA) with higher energies.

  3. A study on beam homogeneity for a Siemens Primus linac.

    PubMed

    Cutanda Henriquez, F; Vargas-Castrillón, S T

    2007-06-01

    Asymmetric offset fields are an important tool for radiotherapy and their suitability for treatment should be assessed. Dose homogeneity for highly asymmetric fields has been studied for a Siemens PRIMUS clinical linear accelerator. Profiles and absolute dose have been measured in fields with two jaws at maximal position (20 cm) and the other two at maximal overtravel (10 cm), corresponding to 10 cm x 10 cm fields with extreme offset. Measured profiles have a marked decreasing gradient towards the beam edge, making these fields unsuitable for treatments. The flattening filter radius is smaller than the primary collimator aperture, and this creates beam inhomogeneities that affect large fields in areas far from the collimator axis, and asymmetric fields with large offset. The results presented assess the effect that the design of the primary collimator and flattening filter assembly has on beam homogeneity. This can have clinical consequences for treatments involving fields that include these inhomogeneous areas. Comparison with calculations from a treatment planning system, Philips Pinnacle v6.3, which computes under the hypotheses of a uniformly flattened beam, results in severe discrepancies.

  4. Study of the neutron beam line shield design for JSNS.

    PubMed

    Kawai, M; Saito, K; Sanami, T; Nakao, N; Maekawa, F

    2005-01-01

    The JSNS, a spallation neutron source of J-PARC (JAERI-KEK Joint Project of the High Intensity Proton Accelerator) has 23 neutron beam lines. In the present study, a database was formulated for an optimum shielding design using the MCNP-X code. The calculations involved two steps. In the first step, the neutron distributions were created in the typical neutron beam line with a model that included the spallation neutron source target. The neutron currents evaluated flowed from the duct into the duct wall which was the boundary source for the bulk shield surrounding the beam line. In the second step, bulk-shield calculations were performed for the various shielding materials (iron, concrete, heavy concrete and so on) used and their composites up to thicknesses of 3 m. The results were compared with each other. Composite material shields of iron and such hydrogeneous materials as polyethylene or concrete were more effective. A typical design was prepared for a beam line within 25 m distance from a moderator, as a sample.

  5. Experimental Studies of Electrons in a Heavy-Ion Beam

    SciTech Connect

    Molvik, A W; Seidl, P A; Bieniosek, F M; Cohen, R H; Faltens, A; Friedman, A; Covo, M K; Lund, S M; Prost, L

    2004-06-23

    Electron cloud effects, ECEs, are normally a problem only in ring accelerators. However, heavy-ion induction linacs for inertial fusion energy have an economic incentive to fit beam tubes tightly to intense beams. This places them at risk from electron clouds produced by emission of electrons and gas from walls. We have measured electron and gas emission from 1 MeV K{sup +} impact on surfaces near grazing incidence on the High-Current Experiment (HCX) at LBNL. Electron emission coefficients reach *values of 130, whereas gas desorption coefficients are near 10{sup 4}. Mitigation techniques are being studied: A bead-blasted rough surface reduces electron emission by a factor of 10 and gas desorption by a factor of 2. Diagnostics are installed on HCX, between and within quadrupole magnets, to measure the beam halo loss, net charge and expelled ions, from which we infer gas density, electron trapping, and the effects of mitigation techniques. Here we discuss a new diagnostic technique that measures gas pressure and electron ionization rates within quadrupole magnets during the beam transit.

  6. A simulation study of radial expansion of an electron beam injected into an ionospheric plasma

    NASA Technical Reports Server (NTRS)

    Koga, J.; Lin, C. S.

    1994-01-01

    Injections of nonrelativistic electron beams from a finite equipotential conductor into an ionospheric plasma have been simulated using a two-dimensional electrostatic particle code. The purpose of the study is to survey the simulation parameters for understanding the dependence of beam radius on physical variables. The conductor is charged to a high potential when the background plasma density is less than the beam density. Beam electrons attracted by the charged conductor are decelerated to zero velocity near the stagnation point, which is at a few Debye lengths from the conductor. The simulations suggest that the beam electrons at the stagnation point receive a large transverse kick and the beam expands radially thereafter. The buildup of beam electrons at the stagnation point produces a large electrostatic force responsible for the transverse kick. However, for the weak charging cases where the background plasma density is larger than the beam density, the radial expansion mechanism is different; the beam plasma instability is found to be responsible for the radial expansion. The simulations show that the electron beam radius for high spacecraft charging cases is of the order of the beam gyroradius, defined as the beam velocity divided by the gyrofrequency. In the weak charging cases, the beam radius is only a fraction of the beam gyroradius. The parameter survey indicates that the beam radius increases with beam density and decreases with magnetic field and beam velocity. The beam radius normalized by the beam gyroradius is found to scale according to the ratio of the beam electron Debye length to the ambient electron Debye length. The parameter dependence deduced would be useful for interpreting the beam radius and beam density of electron beam injection experiments conducted from rockets and the space shuttle.

  7. Recent observations of beam plasma interactions in the ionosphere and a comparison with laboratory studies of the beam plasma discharge

    NASA Technical Reports Server (NTRS)

    Bernstein, W.; Kellogg, P. J.; Monson, S. J.; Holzworth, R. H.; Whalen, B. A.

    1982-01-01

    Experimental results from an electron beam injection rocket flight (27:010 AE) launched into an active aurora are summarized. The rocket carried an accelerator which injected programmed electron beams of less than 100 ma at 2 and 4 kV into the ionospheric plasma over the altitude range 120-240 km. A major objective of the experiment was the study of beam-plasma interactions and the possible identification of the ignition of the beam-plasma discharge (BPD) which had been intensively studied in the laboratory. A qualitative assessment of the data indicates that BPD ignition was produced by both 10 ma and Im beams at 2 and 4 kV. Many of the observed characteristics are similar to the BPD characteristics observed in the laboratory.

  8. Beam Loss Studies for the 2-MW LBNE Proton Beam Line

    SciTech Connect

    Drozhdin, A.I.; Childress, S.R.; Mokhov, N.V.; Tropin, I.S.; Zwaska, R.; /Fermilab

    2012-05-01

    Severe limits are put on allowable beam loss during extraction and transport of a 2.3 MW primary proton beam for the Long Baseline Neutrino Experiment (LBNE) at Fermilab. Detailed simulations with the STRUCT and MARS codes have evaluated the impact of beam loss of 1.6 x 10{sup 14} protons per pulse at 120 GeV, ranging from a single pulse full loss to sustained small fractional loss. It is shown that loss of a single beam pulse at 2.3 MW will result in a catastrophic event: beam pipe destruction, damaged magnets and very high levels of residual radiation inside and outside the tunnel. Acceptable beam loss limits have been determined and robust solutions developed to enable efficient proton beam operation under these constraints.

  9. Study on astrophysical reactions using low-energy RI beams

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Hidetoshi

    2009-10-01

    In recent years, low-energy RI beams can be produced in a good intensity and they have been used for studying many astrophysical reactions. One of the facilities producing low-energy RI beams is CRIB (CNS Radio-Isotope Beam separator) [1,2], an RI-beam separator of Center for Nuclear Study, University of Tokyo. Taking CRIB as an example, recent improvements on the RI-beam production and experimental results on astrophysical studies are presented. Several experimental approaches have been taken for the studies on astrophysical reactions.The feature of each method are discussed based on real measurements performed at CRIB. One is the direct method, applied for measurements of reactions such as (α,p) [3]. Another is the measurement of proton/alpha resonance scattering using the thick target method in inverse kinematics, by which we can obtain information on the resonances relevant in astrophysical reactions [4,5]. A recent fruitful result was from a measurement of proton resonance scattering using a ^7Be beam [5]. The energy level structure of ^8B, revealed by the experiment, is especially of interest as it is related with the ^7Be(p,γ) ^8B reaction, responsible for the production of ^8B neutrinos in the sun. We successfully determined parameters of resonances in ^8B below 6.7 MeV, which may affect the ^7Be(p,γ)^8B reaction rate at the solar temparature. Indirect methods, such as ANC and the Trojan Horse Method, were also used in some of the measurements.[4pt] [1] S. Kubono et al., Eur. Phys. J. A13 (2002) 217.[0pt] [2] Y. Yanagisawa et al., Nucl. Instrum. Meth. Phys. Res., Sect. A 539 (2005) 74.[0pt] [3] M. Notani et al., Nucl. Phys. A 764 (2004) 113c.[0pt] [4] T. Teranishi et al., Phys. Lett. B 650 (2007) 129.[0pt] [5] H. Yamaguchi et al., Phys. Lett. B 672 (2009) 230.

  10. Hip fracture risk estimation based on bone mineral density of a biomechanically guided region of interest: a preliminary study

    NASA Astrophysics Data System (ADS)

    Li, Wenjun; Kornak, John; Li, Caixia; Koyama, Alain; Saeed, Isra; Lu, Ying; Lang, Thomas

    2008-03-01

    We aim to define a biomechanically-guided region of interest inside the proximal femur for improving fracture risk prediction based on bone density measurements. The central hypothesis is that by identifying and focusing on the proximal femoral tissues strongly associated with hip fracture risk, we can provide a better densitometric evaluation of fracture risk compared to current evaluations based on anatomically defined regions of interest using DXA or CT. To achieve this, we have constructed a hip statistical atlas of quantitative computed tomography (QCT) images by applying rigid and non-rigid inter-subject image registration to transform hip QCT scans of 15 fractured patients and 15 controls into a common reference space, and performed voxel-by-voxel t-tests between the two groups to identify bone tissues that showed the strongest relevance to hip fracture. Based on identification of this fracture-relevant tissue volume, we have generated a biomechanically-guided region of interest (B-ROI). We have applied BMD measured from this new region of interest to discriminate the fractured patients and controls, and compared it to BMD measured in the total proximal femur. For the femur ROI approach, the BMD values of the fractured patients and the controls had an overlap of 60 mg/cm 3, and only 1 out of 15 fractured patients had BMD below the overlap region; for the B-ROI approach, a much narrower BMD overlap region of 28 mg/cm 3 was observed, and 11 out of 15 fractured patients had BMDs below the overlap region.

  11. Role of Aquaporin 0 in lens biomechanics.

    PubMed

    Sindhu Kumari, S; Gupta, Neha; Shiels, Alan; FitzGerald, Paul G; Menon, Anil G; Mathias, Richard T; Varadaraj, Kulandaiappan

    2015-07-10

    Maintenance of proper biomechanics of the eye lens is important for its structural integrity and for the process of accommodation to focus near and far objects. Several studies have shown that specialized cytoskeletal systems such as the beaded filament (BF) and spectrin-actin networks contribute to mammalian lens biomechanics; mutations or deletion in these proteins alters lens biomechanics. Aquaporin 0 (AQP0), which constitutes ∼45% of the total membrane proteins of lens fiber cells, has been shown to function as a water channel and a structural cell-to-cell adhesion (CTCA) protein. Our recent ex vivo study on AQP0 knockout (AQP0 KO) mouse lenses showed the CTCA function of AQP0 could be crucial for establishing the refractive index gradient. However, biomechanical studies on the role of AQP0 are lacking. The present investigation used wild type (WT), AQP5 KO (AQP5(-/-)), AQP0 KO (heterozygous KO: AQP0(+/-); homozygous KO: AQP0(-/-); all in C57BL/6J) and WT-FVB/N mouse lenses to learn more about the role of fiber cell AQPs in lens biomechanics. Electron microscopic images exhibited decreases in lens fiber cell compaction and increases in extracellular space due to deletion of even one allele of AQP0. Biomechanical assay revealed that loss of one or both alleles of AQP0 caused a significant reduction in the compressive load-bearing capacity of the lenses compared to WT lenses. Conversely, loss of AQP5 did not alter the lens load-bearing ability. Compressive load-bearing at the suture area of AQP0(+/-) lenses showed easy separation while WT lens suture remained intact. These data from KO mouse lenses in conjunction with previous studies on lens-specific BF proteins (CP49 and filensin) suggest that AQP0 and BF proteins could act co-operatively in establishing normal lens biomechanics. We hypothesize that AQP0, with its prolific expression at the fiber cell membrane, could provide anchorage for cytoskeletal structures like BFs and together they help to confer

  12. Crossed-beam studies of the dynamics of radical reactions

    SciTech Connect

    Liu, K.

    1993-12-01

    The objective of this program is to characterize the detailed dynamics of elementary radical reactions and to provide a better understanding of radical reactivity in general. The radical beam is typically generated by a laser photolysis method. After colliding with the reacting molecule in a crossed-beam apparatus, the reaction product state distribution is interrogated by laser spectroscopic techniques. Several radicals of combustion significance, such as O, CH, OH, CN and NCO have been successfully generated and their collisional behavior at the state-to-state integral cross section level of detail has been studied in this manner. During the past year, the detection system has been converted from LIF to REMPI schemes, and the emphasis of this program shifted to investigate the product angular distributions. Both inelastic and reactive processes have been studied.

  13. A Biomechanical Analysis of the Karate Chop.

    ERIC Educational Resources Information Center

    Cavanagh, Peter R.; Landa, Jean

    Although the sport of karate has been somewhat neglected by scientists, the following two isolated biomechanical studies exist in literature: (1) tracings of a karate chop in two planes were presented, but no data was given concerning the rates of movement of the limb segments, and (2) pre- and postimpact phenomena of five subjects were studied,…

  14. Electrostatic ion beam trap for electron collision studies

    SciTech Connect

    Heber, O.; Witte, P.D.; Diner, A.; Bhushan, K.G.; Strasser, D.; Toker, Y.; Rappaport, M.L.; Ben-Itzhak, I.; Altstein, N.; Schwalm, D.; Wolf, A.; Zajfman, D.

    2005-01-01

    We describe a system combining an ion beam trap and a low energy electron target in which the interaction between electrons and vibrationally cold molecular ions and clusters can be studied. The entire system uses only electrostatic fields for both trapping and focusing, thus being able to store particles without a mass limit. Preliminary results for the electron impact neutralization of C{sub 2}{sup -} ions and aluminum clusters are presented.

  15. Use of exotic nuclear beams for nuclear structure studies

    SciTech Connect

    Sugimoto, K.

    1984-10-01

    Possible experiments are discussed for nuclear structure studies using, as secondary beams, projectile fragments produced by high-energy heavy-ion collisions. They are, specifically, (a) determination of nuclear sizes from measurements of the total interaction cross sections of nucleus-nucleus collisions, and (b) determination of static electromagnetic moments, ..mu..'s and Q's, of short-lived ..beta..-radioactive nuclei. 9 references.

  16. Outrun or Outmaneuver: Predator-Prey Interactions as a Model System for Integrating Biomechanical Studies in a Broader Ecological and Evolutionary Context.

    PubMed

    Moore, Talia Y; Biewener, Andrew A

    2015-12-01

    Behavioral studies performed in natural habitats provide a context for the development of hypotheses and the design of experiments relevant both to biomechanics and to evolution. In particular, predator-prey interactions are a model system for integrative study because success or failure of predation has a direct effect on fitness and drives the evolution of specialized performance in both predator and prey. Although all predators share the goal of capturing prey, and all prey share the goal of survival, the behavior of predators and prey are diverse in nature. This article presents studies of some predator-prey interactions sharing common predation strategies that reveal general principles governing the behaviors of predator and prey, even in distantly related taxa. Studies of predator-prey interactions also reveal that maximal performance observed in a laboratory setting is not necessarily the performance that determines fitness. Thus, considering locomotion in the context of predation ecology can aid in evolutionarily relevant experimental design. Classification by strategy reveals that displaying unpredictable trajectories is a relevant anti-predator behavior in response to multiple predation strategies. A predator's perception and pursuit of prey can be affected indirectly by divergent locomotion of similar animals that share an ecosystem. Variation in speed and direction of locomotion that directly increases the unpredictability of a prey's trajectory can be increased through genetic mutation that affects locomotor patterns, musculoskeletal changes that affect maneuverability, and physical interactions between an animal and the environment. By considering the interconnectedness of ecology, physical constraints, and the evolutionary history of behavior, studies in biomechanics can be designed to inform each of these fields.

  17. Recent Direct Reaction Experimental Studies with Radioactive Tin Beams

    SciTech Connect

    Jones, K. L.; Ahn, S.; Allmond, J. M.; Ayres, A.; Bardayan, D. W.; Baugher, T.; Bazin, D.; Berryman, J. S.; Bey, A.; Bingham, C.; Cartegni, L.; Cerizza, G.; Chae, K. Y.; Cizewski, J. A.; Gade, A.; Galindo-Uribarri, A.; Garcia-Ruiz, R. F.; Grzywacz, R.; Howard, M. E.; Kozub, R. L.; Liang, J. F.; Manning, B.; Matoš, M.; McDaniel, S.; Miller, D.; Nesaraja, C. D.; O'Malley, P. D.; Padgett, S.; Padilla-Rodal, E.; Pain, S. D.; Pittman, S. T.; Radford, D. C.; Ratkiewicz, A.; Schmitt, K. T.; Shore, A.; Smith, M. S.; Stracener, D. W.; Stroberg, S. R.; Tostevin, J.; Varner, R. L.; Weisshaar, D.; Wimmer, K.; Winkler, R.

    2015-01-01

    Direct reaction techniques are powerful tools to study the single-particle nature of nuclei. Performing direct reactions on short-lived nuclei requires radioactive ion beams produced either via fragmentation or the Isotope Separation OnLine (ISOL) method. Some of the most interesting regions to study with direct reactions are close to the magic numbers where changes in shell structure can be tracked. These changes can impact the final abundances of explosive nucleosynthesis. The structure of the chain of tin isotopes is strongly influenced by the Z = 50 proton shell closure, as well as the neutron shell closures lying in the neutron-rich, N = 82, and neutron-deficient, N = 50, regions. Here, we present two examples of direct reactions on exotic tin isotopes. The first uses a one-neutron transfer reaction and a low-energy reaccelerated ISOL beam to study states in Sn-131 from across the N = 82 shell closure. The second example utilizes a one-neutron knockout reaction on fragmentation beams of neutron-deficient Sn-106,108Sn. In conclusion, In both cases, measurements of γ rays in coincidence with charged particles proved to be invaluable.

  18. Recent Direct Reaction Experimental Studies with Radioactive Tin Beams

    DOE PAGES

    Jones, K. L.; Ahn, S.; Allmond, J. M.; ...

    2015-01-01

    Direct reaction techniques are powerful tools to study the single-particle nature of nuclei. Performing direct reactions on short-lived nuclei requires radioactive ion beams produced either via fragmentation or the Isotope Separation OnLine (ISOL) method. Some of the most interesting regions to study with direct reactions are close to the magic numbers where changes in shell structure can be tracked. These changes can impact the final abundances of explosive nucleosynthesis. The structure of the chain of tin isotopes is strongly influenced by the Z = 50 proton shell closure, as well as the neutron shell closures lying in the neutron-rich, Nmore » = 82, and neutron-deficient, N = 50, regions. Here, we present two examples of direct reactions on exotic tin isotopes. The first uses a one-neutron transfer reaction and a low-energy reaccelerated ISOL beam to study states in Sn-131 from across the N = 82 shell closure. The second example utilizes a one-neutron knockout reaction on fragmentation beams of neutron-deficient Sn-106,108Sn. In conclusion, In both cases, measurements of γ rays in coincidence with charged particles proved to be invaluable.« less

  19. Biomechanics of Disc Degeneration

    PubMed Central

    Palepu, V.; Kodigudla, M.; Goel, V. K.

    2012-01-01

    Disc degeneration and associated disorders are among the most debated topics in the orthopedic literature over the past few decades. These may be attributed to interrelated mechanical, biochemical, and environmental factors. The treatment options vary from conservative approaches to surgery, depending on the severity of degeneration and response to conservative therapies. Spinal fusion is considered to be the “gold standard” in surgical methods till date. However, the association of adjacent level degeneration has led to the evolution of motion preservation technologies like spinal arthroplasty and posterior dynamic stabilization systems. These new technologies are aimed to address pain and preserve motion while maintaining a proper load sharing among various spinal elements. This paper provides an elaborative biomechanical review of the technologies aimed to address the disc degeneration and reiterates the point that biomechanical efficacy followed by long-term clinical success will allow these nonfusion technologies as alternatives to fusion, at least in certain patient population. PMID:22745914

  20. Beam Line Design and Beam Physics Study of Energy Recovery Linac Free Electron Laser at Peking University

    SciTech Connect

    Wang, Guimei

    2011-12-31

    Energy recovering linac (ERL) offers an attractive alternative for generating intense beams of charged particles by approaching the operational efficiency of a storage ring while maintaining the superior beam quality typical of a linear accelerator. In ERLs, the decelerated beam cancels the beam loading effects of the accelerated beam with high repetition rate. Therefore, ERLs can, in principle, accelerate very high average currents with only modest amounts of RF power. So the efficiency of RF power to beam is much higher. Furthermore, the energy of beam to dump is lower, so it will reduce dump radiation. With the successful experiments in large maximum-to-injection energy ratio up to 51:1 and high power FEL up to 14kW, the use of ERL, especially combining with superconducting RF technology, provides a potentially powerful new paradigm for generation of the charged particle beams used in MW FEL, synchrotron radiation sources, high-energy electron cooling devices and so on. The 3+1/2 DC-SC photo injector and two 9cell TESLA superconducting cavity for IR SASE FEL in PKU provides a good platform to achieve high average FEL with Energy Recovery. The work of this thesis is on Beam line design and Beam dynamics study of Energy Recovery Linac Free Electron Laser for Peking University. It is the upgrade of PKU facility, which is under construction. With ERL, this facility can work in CW mode, so it can operate high average beam current without RF power constraint in main linac and generate high average FEL power. Moreover, it provides a test facility to study the key technology in ERL. System parameters are optimized for PKU ERL-FEL. The oscillation FEL output power is studied with different bunch charge, transverse emittance, bunch length and energy spread. The theory of optimal RF power and Q{sub ext} with ERL and without ERL is analyzed and applied to PKU injector and linac including microphonic effect. pace charge effect in the injector and merger is studied for beam

  1. Experimental Studying of Dust Particles Charging by Electron Beam

    SciTech Connect

    Gavrikov, A. V.; Fortov, V. E.; Petrov, O. F.; Vorona, N. A.; Vasiliev, M. N.

    2008-09-07

    The studying of the dusty plasma properties under electron beam action are of great interest because it gives the unique opportunities for experimental investigation of strongly coupled systems as well as for developing the new dusty plasma technologies of creating the new composite materials. Highly charged dust particle generates electrostatic field that can accelerate positive ions to high power. It gives the unique possibilities of using these macroparticles (for deeply ions implantation, as catalysts for increasing rate of reactions with the high energy barrier, in the new ionic engines etc.). Presented work deals with the experimental investigation of dust particles charging under direct influence of electron beam. On the basis of experimental data the average velocities of dust particles were obtained and the charge of macroparticle was estimated.

  2. A Study of Effects of Tissue Inhomogeneity on HIFU Beam

    NASA Astrophysics Data System (ADS)

    Amin, Viren; Roberts, Ron; Long, Tao; Thompson, R. B.; Ryken, Timothy

    2006-05-01

    The potential of high-intensity focused ultrasound (HIFU) will not be realized unless the effects of overlaying tissues are understood in such a way that allows for estimation of HIFU dose distribution at a target tissue. We employ computational models to examine the impact of phase aberration on tissue ablation. Thompson and Roberts have recently studied the effects of phase aberration on ultrasound focusing in aerospace engine materials such as titanium alloy, and have developed a computational model to examine these effects. The ultrasound beam observed after transmission through the fused quartz (homogeneous) and that observed after transmission through the titanium (inhomogeneous) demonstrate the severe beam wavefield amplitude distortion introduced by the velocity inhomogeneity-induced phase aberration. We study applicability of this approach to model phase aberration in inhomogeneous tissues and its effect on HIFU dose distribution around the focus. It is hypothesized that the ill-effects of phase aberration accumulate during propagation through intervening tissue in which field intensities are substantially lower than that in the focal zone, and it is therefore appropriate to use a linear acoustic model to describe the transport of energy from the transducer to the volume targeted for ablation. We present initial results of the simulation and experiments of beam measurements under water without and with different tissue layers.

  3. Biomechanics, exercise physiology, and the 75th anniversary of RQES.

    PubMed

    Hamill, Joseph; Haymes, Emily M

    2005-06-01

    The purpose of this paper is to review the biomechanics and exercise physiology studies published in the Research Quarterly for Exercise and Sport (RQES) over the past 75 years. Studies in biomechanics, a relatively new subdiscipline that evolved from kinesiology, first appeared in the journal about 40 years ago. Exercise physiology studies have been published in RQES throughout its history. Studies in both subdisciplines reflect areas of research that were of great interest at the time of their publication. Many of the leading scholars, past and present, in both biomechanics and exercise physiology were authors of papers in RQES.

  4. Study of beam optics and beam halo by integrated modeling of negative ion beams from plasma meniscus formation to beam acceleration

    SciTech Connect

    Miyamoto, K.; Okuda, S.; Hatayama, A.; Hanada, M.; Kojima, A.

    2013-01-14

    To understand the physical mechanism of the beam halo formation in negative ion beams, a two-dimensional particle-in-cell code for simulating the trajectories of negative ions created via surface production has been developed. The simulation code reproduces a beam halo observed in an actual negative ion beam. The negative ions extracted from the periphery of the plasma meniscus (an electro-static lens in a source plasma) are over-focused in the extractor due to large curvature of the meniscus.

  5. Influence of loading cycle profile and frequency on a biomechanical parameter of a model of a balloon kyphoplasty-augmented lumbar spine segment: a finite element analysis study.

    PubMed

    Li, Yuan; Lewis, Gladius

    2010-01-01

    For patients who are suffering debilitating and persistent pain due to vertebral compression fracture(s) and for whom conservative therapies have not provided relief, balloon kyphoplasty (BKP) is used as a surgical option. There are only a very few literature reports on the use of the finite element analysis (FEA) method to obtain biomechanical parameters of models of spine segments that include BKP augmentation at a given level. In each of these studies, the applied loading used was quasi-static. During normal activities of daily living, the patient's spine would be subject to dynamically-applied loading. Thus, the question of the influence of the characteristics of a dynamically-applied loading cycle on biomechanical parameters of a spine that includes BKP-augmented segment(s) is germane; however, a study of this issue is lacking. We investigated this issue in the present FEA work, with the spine segment model being the L1-L3 motion segment units (MSUs) (a segment that is commonly augmented using BKP) and prophylactic BKP simulated at L2. The dynamic load was the compressive load-versus-time cycle to which the L3-L4 MSU is subjected during gait. Four cases of the cycle were considered, corresponding to slow-, normal-, fast- and very fast-paced gait. The loading cycle was applied to the superior surface of L1 while the inferior surface of L3 was fully constrained. It was found that (1) the global mean von Mises stress during the loading cycle (σVMG), in each tissue in the model increased in going from a slow-paced gait cycle to a very fast-paced gait cycle; and (2) for the slow-paced gait cycle, with increase in frequency of the cycle, f (1 ≤ f ≤ 3 Hz), σVMG in each of these tissues increased. Potential uses of the present findings are identified.

  6. Effects of sodium-hyaluronate and glucosamine-chondroitin sulfate on remodeling stage of tenotomized superficial digital flexor tendon in rabbits: a clinical, histopathological, ultrastructural, and biomechanical study.

    PubMed

    Oryan, Ahmad; Moshiri, Ali; Meimandiparizi, Abdul-Hamid

    2011-01-01

    This study was designed to evaluate the effects of sodium-hyaluronate (NaH) combined with glucosamine HCl-chondroitin sulfate (GlcN-CS) on the post-surgical repair of tendon rupture on day 84 post injury. Twenty white New Zealand female rabbits were divided randomly into two equal groups of injured treated and injured untreated. After tenotomy and surgical repair, using the modified Kessler technique and running pattern, the injured legs were casted for 14 days. NaH was injected subcutaneously over the lesion on days 3, 7, and 10 and was followed by daily oral administration of GlcN-CS on days 3 to 23 post injury. The control animals received normal saline injection and oral placebo similarly. The weight of the animals, tendon diameter, clinical manifestations, and radiographic and ultrasonographic evaluations were conducted for 12 weeks. The rabbits were euthanized 84 days post injury and the tendons were evaluated at macroscopic, histopathologic, and ultrastructural level and were assessed for biomechanical and percentage dry-weight parameters. Treatment significantly reduced the tendon diameter and ultimate and yield strain, and increased the echogenicity, dry-weight content, ultimate and yield strength, and stress and stiffness of the injured tendons compared to those of the untreated ones. Treatment also significantly enhanced the maturation rate of the tenoblasts, fibrillogenesis, the diameters of the collagen fibrils, and fibrillar density. These findings suggest that a combined treatment of NaH and GlcN-CS could be effective in restoring the morphological and biomechanical properties of injured superficial digital flexor tendon of rabbits and might be helpful for future clinical trial studies in tendon ruptures.

  7. A Biomechanical Modeling Guided CBCT Estimation Technique.

    PubMed

    Zhang, You; Tehrani, Joubin Nasehi; Wang, Jing

    2017-02-01

    Two-dimensional-to-three-dimensional (2D-3D) deformation has emerged as a new technique to estimate cone-beam computed tomography (CBCT) images. The technique is based on deforming a prior high-quality 3D CT/CBCT image to form a new CBCT image, guided by limited-view 2D projections. The accuracy of this intensity-based technique, however, is often limited in low-contrast image regions with subtle intensity differences. The solved deformation vector fields (DVFs) can also be biomechanically unrealistic. To address these problems, we have developed a biomechanical modeling guided CBCT estimation technique (Bio-CBCT-est) by combining 2D-3D deformation with finite element analysis (FEA)-based biomechanical modeling of anatomical structures. Specifically, Bio-CBCT-est first extracts the 2D-3D deformation-generated displacement vectors at the high-contrast anatomical structure boundaries. The extracted surface deformation fields are subsequently used as the boundary conditions to drive structure-based FEA to correct and fine-tune the overall deformation fields, especially those at low-contrast regions within the structure. The resulting FEA-corrected deformation fields are then fed back into 2D-3D deformation to form an iterative loop, combining the benefits of intensity-based deformation and biomechanical modeling for CBCT estimation. Using eleven lung cancer patient cases, the accuracy of the Bio-CBCT-est technique has been compared to that of the 2D-3D deformation technique and the traditional CBCT reconstruction techniques. The accuracy was evaluated in the image domain, and also in the DVF domain through clinician-tracked lung landmarks.

  8. SPS ionosphere/microwave beam interactions: Arecibo experimental studies

    SciTech Connect

    Duncan, L.M.

    1980-10-01

    The purpose of this program is to determine the environmental impacts associated with the operation of the proposed SPS microwave power transmission system. It is expected that thermal effects will provide the dominant force driving the nonlinear ionosphere/microwave beam interactions. Collisional damping of radio waves, producing ohmic heating of the ionospheric plasma, depends inversely on the square of the radio wave frequency. Therefore, equivalent heating and equivalent thermal forces can be generated at lower radiated power densities by using lower radio wave frequencies. This principle is fundamental to a large part of the experimental program. An understanding of the physics of the specific interactions excited by the SPS microwave beam is also an important part of the assessment program. This program is designed to determine instability thresholds, the growth rates and spatial extent of the resultant ionospheric disturbances, and the frequency and power dependences of the interactions. How these interactions are affected by variations in the natural ionospheric conditions, how different instabilities occurring simultaneously may affect each other, and how distinct microwave beams might mutually interact are studied. Status of the program is described. (WHK)

  9. Radiobiological study by using laser-driven proton beams

    SciTech Connect

    Yogo, A.; Nishikino, M.; Mori, M.; Ogura, K.; Sagisaka, A.; Orimo, S.; Nishiuchi, M.; Pirozhkov, A. S.; Ikegami, M.; Tampo, M.; Sakaki, H.; Suzuki, M.; Daito, I.; Kiriyama, H.; Okada, H.; Kanazawa, S.; Kondo, S.; Shimomura, T.; Nakai, Y.; Kawachi, T.

    2009-07-25

    Particle acceleration driven by high-intensity laser systems is widely attracting interest as a potential alternative to conventional ion acceleration, including ion accelerator applications to tumor therapy. Recent works have shown that a high intensity laser pulse can produce single proton bunches of a high current and a short pulse duration. This unique feature of laser-ion acceleration can lead to progress in the development of novel ion sources. However, there has been no experimental study of the biological effects of laser-driven ion beams. We describe in this report the first demonstrated irradiation effect of laser-accelerated protons on human lung cancer cells. In-vitro A549 cells are irradiated with a proton dose of 20 Gy, resulting in a distinct formation of gamma-H2AX foci as an indicator of DNA double-strand breaks. This is a pioneering result that points to future investigations of the radiobiological effects of laser-driven ion beams. The laser-driven ion beam is apotential excitation source for time-resolved determination of hydroxyl (OH) radical yield, which will explore relationship between the fundamental chemical reactions of radiation effects and consequent biological processes.

  10. Biomechanical Stability of Dental Implants in Augmented Maxillary Sites: Results of a Randomized Clinical Study with Four Different Biomaterials and PRF and a Biological View on Guided Bone Regeneration

    PubMed Central

    Angelo, Troedhan; Marcel, Wainwright; Andreas, Kurrek; Izabela, Schlichting

    2015-01-01

    Introduction. Bone regenerates mainly by periosteal and endosteal humoral and cellular activity, which is given only little concern in surgical techniques and choice of bone grafts for guided bone regeneration. This study investigates on a clinical level the biomechanical stability of augmented sites in maxillary bone when a new class of moldable, self-hardening calcium-phosphate biomaterials (SHB) is used with and without the addition of Platelet Rich Fibrin (aPRF) in the Piezotome-enhanced subperiosteal tunnel-technique (PeSPTT). Material and Methods. 82 patients with horizontal atrophy of anterior maxillary crest were treated with PeSPTT and randomly assigned biphasic (60% HA/40% bTCP) or monophasic (100% bTCP) SHB without or with addition of aPRF. 109 implants were inserted into the augmented sites after 8.3 months and the insertion-torque-value (ITV) measured as clinical expression of the (bio)mechanical stability of the augmented bone and compared to ITVs of a prior study in sinus lifting. Results. Significant better results of (bio)mechanical stability almost by two-fold, expressed by higher ITVs compared to native bone, were achieved with the used biomaterials and more constant results with the addition of aPRF. Conclusion. The use of SHB alone or combined with aPRF seems to be favourable to achieve a superior (bio)mechanical stable restored alveolar bone. PMID:25954758

  11. Neutralized ion beam modification of cellulose membranes for study of ion charge effect on ion-beam-induced DNA transfer

    NASA Astrophysics Data System (ADS)

    Prakrajang, K.; Sangwijit, K.; Anuntalabhochai, S.; Wanichapichart, P.; Yu, L. D.

    2012-02-01

    Low-energy ion beam biotechnology (IBBT) has recently been rapidly developed worldwide. Ion-beam-induced DNA transfer is one of the important applications of IBBT. However, mechanisms involved in this application are not yet well understood. In this study plasma-neutralized ion beam was applied to investigate ion charge effect on induction of DNA transfer. Argon ion beam at 7.5 keV was neutralized by RF-driven plasma in the beam path and then bombarded cellulose membranes which were used as the mimetic plant cell envelope. Electrical properties such as impedance and capacitance of the membranes were measured after the bombardment. An in vitro experiment on plasmid DNA transfer through the cellulose membrane was followed up. The results showed that the ion charge input played an important role in the impedance and capacitance changes which would affect DNA transfer. Generally speaking, neutral particle beam bombardment of biologic cells was more effective in inducing DNA transfer than charged ion beam bombardment.

  12. The biomechanics of solids and fluids: the physics of life

    NASA Astrophysics Data System (ADS)

    Alexander, David E.

    2016-09-01

    Biomechanics borrows and extends engineering techniques to study the mechanical properties of organisms and their environments. Like physicists and engineers, biomechanics researchers tend to specialize on either fluids or solids (but some do both). For solid materials, the stress-strain curve reveals such useful information as various moduli, ultimate strength, extensibility, and work of fracture. Few biological materials are linearly elastic so modified elastic moduli are defined. Although biological materials tend to be less stiff than engineered materials, biomaterials tend to be tougher due to their anisotropy and high extensibility. Biological beams are usually hollow cylinders; particularly in plants, beams and columns tend to have high twist-to-bend ratios. Air and water are the dominant biological fluids. Fluids generate both viscous and pressure drag (normalized as drag coefficients) and the Reynolds number (Re) gives their relative importance. The no-slip conditions leads to velocity gradients (‘boundary layers’) on surfaces and parabolic flow profiles in tubes. Rather than rigidly resisting drag in external flows, many plants and sessile animals reconfigure to reduce drag as speed increases. Living in velocity gradients can be beneficial for attachment but challenging for capturing particulate food. Lift produced by airfoils and hydrofoils is used to produce thrust by all flying animals and many swimming ones, and is usually optimal at higher Re. At low Re, most swimmers use drag-based mechanisms. A few swimmers use jetting for rapid escape despite its energetic inefficiency. At low Re, suspension feeding depends on mechanisms other than direct sieving because thick boundary layers reduce effective porosity. Most biomaterials exhibit a combination of solid and fluid properties, i.e., viscoelasticity. Even rigid biomaterials exhibit creep over many days, whereas pliant biomaterials may exhibit creep over hours or minutes. Instead of rigid materials

  13. A study on the role of articular cartilage soft tissue constitutive form in models of whole knee biomechanics.

    PubMed

    Marchi, Benjamin C; Arruda, Ellen M

    2017-02-01

    The mechanical behaviors of biological soft tissues are challenging to describe abstractly, with each individual tissue potentially characterized by its own unique nonlinear, anisotropic, and viscoelastic properties. These complexities are exacerbated by patient to patient variability, both mechanically and anatomically, and by inherent constitutive heterogeneity. Despite these challenges, computational models of whole knee biomechanics can be instrumental in describing the onset and progression of injury and disease. In this work, a three-dimensional whole knee computational model was developed using patient-specific anatomy, containing tissues with constitutive relationships built from relevant experimental investigations. In an effort to address the common assumption of linear elastic descriptions of articular cartilage in whole knee models, this work investigates the implications, with respect to macroscopic kinematics and local deformation, of incorporating physiologically motivated and mechanically accurate constitutive heterogeneity in articular cartilage, highlighting the sensitivities of each corresponding level of constitutive complexity. We show how the inclusion of representative cartilage material models affects deformation distributions within the joint, as well as relative joint motion. In particular, the assumption of linear elasticity in articular cartilage results in an overprediction of joint motion and significantly affects predicted local cartilage strains, while full-field, mechanically heterogeneous cartilage descriptions have a less drastic effect at both the tissue and joint levels. Nonetheless, joints containing complete descriptions of articular cartilage heterogeneity may be an integral component in building comprehensive computational tools to advance our understanding of injury and disease mechanisms.

  14. Icariin Promotes Tendon-Bone Healing during Repair of Rotator Cuff Tears: A Biomechanical and Histological Study

    PubMed Central

    Ye, Chenyi; Zhang, Wei; Wang, Shengdong; Jiang, Shuai; Yu, Yuanbin; Chen, Erman; Xue, Deting; Chen, Jianzhong; He, Rongxin

    2016-01-01

    To investigate whether the systematic administration of icariin (ICA) promotes tendon-bone healing after rotator cuff reconstruction in vivo, a total of 64 male Sprague Dawley rats were used in a rotator cuff injury model and underwent rotator cuff reconstruction (bone tunnel suture fixation). Rats from the ICA group (n = 32) were gavage-fed daily with ICA at 0.125 mg/g, while rats in the control group (n = 32) received saline only. Micro-computed tomography, biomechanical tests, serum ELISA (calcium; Ca, alkaline phosphatase; AP, osteocalcin; OCN) and histological examinations (Safranin O and Fast Green staining, type I, II and III collagen (Col1, Col2, and Col3), CD31, and vascular endothelial growth factor (VEGF)) were analyzed two and four weeks after surgery. In the ICA group, the serum levels of AP and OCN were higher than in the control group. More Col1-, Col2-, CD31-, and VEGF-positive cells, together with a greater degree of osteogenesis, were detected in the ICA group compared with the control group. During mechanical testing, the ICA group showed a significantly higher ultimate failure load than the control group at both two and four weeks. Our results indicate that the systematic administration of ICA could promote angiogenesis and tendon-bone healing after rotator cuff reconstruction, with superior mechanical strength compared with the controls. Treatment for rotator cuff injury using systematically-administered ICA could be a promising strategy. PMID:27792147

  15. Icariin Promotes Tendon-Bone Healing during Repair of Rotator Cuff Tears: A Biomechanical and Histological Study.

    PubMed

    Ye, Chenyi; Zhang, Wei; Wang, Shengdong; Jiang, Shuai; Yu, Yuanbin; Chen, Erman; Xue, Deting; Chen, Jianzhong; He, Rongxin

    2016-10-25

    To investigate whether the systematic administration of icariin (ICA) promotes tendon-bone healing after rotator cuff reconstruction in vivo, a total of 64 male Sprague Dawley rats were used in a rotator cuff injury model and underwent rotator cuff reconstruction (bone tunnel suture fixation). Rats from the ICA group (n = 32) were gavage-fed daily with ICA at 0.125 mg/g, while rats in the control group (n = 32) received saline only. Micro-computed tomography, biomechanical tests, serum ELISA (calcium; Ca, alkaline phosphatase; AP, osteocalcin; OCN) and histological examinations (Safranin O and Fast Green staining, type I, II and III collagen (Col1, Col2, and Col3), CD31, and vascular endothelial growth factor (VEGF)) were analyzed two and four weeks after surgery. In the ICA group, the serum levels of AP and OCN were higher than in the control group. More Col1-, Col2-, CD31-, and VEGF-positive cells, together with a greater degree of osteogenesis, were detected in the ICA group compared with the control group. During mechanical testing, the ICA group showed a significantly higher ultimate failure load than the control group at both two and four weeks. Our results indicate that the systematic administration of ICA could promote angiogenesis and tendon-bone healing after rotator cuff reconstruction, with superior mechanical strength compared with the controls. Treatment for rotator cuff injury using systematically-administered ICA could be a promising strategy.

  16. Design study of low-energy beam transport for multi-charge beams at RAON

    NASA Astrophysics Data System (ADS)

    Bahng, Jungbae; Qiang, Ji; Kim, Eun-San

    2015-12-01

    The Rare isotope Accelerator Of Newness (RAON) at the Rare Isotope Science Project (RISP) is being designed to simultaneously accelerate beams with multiple charge states. It includes a driver superconducting (SC) linac for producing 200 MeV/u and 400 kW continuous wave (CW) heavy ion beams from protons to uranium. The RAON consists of a few electron cyclotron resonance ion sources, a low-energy beam transport (LEBT) system, a CW 81.25 MHz, 500 keV/u radio frequency quadrupole (RFQ) accelerator, a medium-energy beam transport system, the SC linac, and a charge-stripper system. The LEBT system for the RISP accelerator facility consists of a high-voltage platform, two 90° dipoles, a multi-harmonic buncher (MHB), solenoids, electrostatic quadrupoles, a velocity equalizer, and a diagnostic system. The ECR ion sources are located on a high-voltage platform to reach an initial beam energy of 10 keV/u. After extraction, the ion beam is transported through the LEBT system to the RFQ accelerator. The generated charge states are selected by an achromatic bending system and then bunched by the MHB in the LEBT system. The MHB is used to achieve a small longitudinal emittance in the RFQ by generating a sawtooth wave with three harmonics. In this paper, we present the results and issues of the beam dynamics of the LEBT system.

  17. Teaching undergraduate biomechanics with Just-in-Time Teaching.

    PubMed

    Riskowski, Jody L

    2015-06-01

    Biomechanics education is a vital component of kinesiology, sports medicine, and physical education, as well as for many biomedical engineering and bioengineering undergraduate programmes. Little research exists regarding effective teaching strategies for biomechanics. However, prior work suggests that student learning in undergraduate physics courses has been aided by using the Just-in-Time Teaching (JiTT). As physics understanding plays a role in biomechanics understanding, the purpose of study was to evaluate the use of a JiTT framework in an undergraduate biomechanics course. This two-year action-based research study evaluated three JiTT frameworks: (1) no JiTT; (2) mathematics-based JiTT; and (3) concept-based JiTT. A pre- and post-course assessment of student learning used the biomechanics concept inventory and a biomechanics concept map. A general linear model assessed differences between the course assessments by JiTT framework in order to evaluate learning and teaching effectiveness. The results indicated significantly higher learning gains and better conceptual understanding in a concept-based JiTT course, relative to a mathematics-based JiTT or no JiTT course structure. These results suggest that a course structure involving concept-based questions using a JiTT strategy may be an effective method for engaging undergraduate students and promoting learning in biomechanics courses.

  18. Experimental study on full-scale steel beam-to-column moment connections

    NASA Astrophysics Data System (ADS)

    Qian, Jiaru; Yu, Haiqun; Yan, Feng; Dong, Hai; Li, Jianhua; Liu, Yueming

    2005-12-01

    Ten full-scale steel beam-to-column moment connections used in moment-resisting frames (MRFs) were tested to study the failure process, failure mode, strength and plastic rotation capacity. The specimens include one traditional welded flange-bolted web connection, one traditional fully welded connection, four beam flange strengthened connections, three beam flange weakened connections, and one through-diaphragm connection. The test results show that the connections with flange cover plates or with partly cut beam flanges satisfy the beam plastic rotation demand for ductile MRFs. From the measured stress profiles along the beam flange and beam web depth, the mechanics of brittle fracture at the end of the beam is discussed. Design recommendations for steel beam-to-column moment connections are proposed.

  19. Proposal of a beam study in the AGS Booster

    SciTech Connect

    Machida, S.; Chen, S.

    1991-10-01

    IN order to achieve the design luminosity, the Superconducting Super Collider (SSC) parameter choices emphasize the preservation of the transverse emittance requiring in the collider a normalized transverse emittance of 1 {pi}.mm.mrad. A stringent accelerator chain emittance budget must be maintained to achieve the final value. Budgeted emittance specifications for the Low Energy Booster (LEB) include 0.4 {pi}.mm.mrad at injection and {le} 0.6 {pi}.mm.mrad at extraction. The space-charge tune shift is expected to be more than 0.5 when the rms normalized emittance of 0.4 {pi}.mm.mrad at injection and the total number of particles is 1.1 {times} 10{sup 12} with 1 {times} 10{sup 10} particles per bunch. Therefore, it is necessary to cope with a large tune shift and avoid emittance deterioration. We have been studying the beam emittance evolution in the LEB by a multi-particle simulation code with space-charge effects. As reported in the several papers we have obtained from the simulation some new insights into the effects which seem to explain qualitatively a cause of the emittance growth. Even quantitatively, we believe that the simulation can predict the emittance growth as a function of time quite accurately because the code includes most details of the physics processes, such as the adiabatic bunching process and acceleration in the fully 6-D phase space treatment, transverse as well as longitudinal space-charge calculations in a self-consistent manner, and intensity decrease due to particle loss. The purpose of this study is to determine quantitatively the emittance deterioration due to space-charge effects, not to find the maximum current an accelerator could accommodate. Since the charge distribution itself may not remain the same, an accurate measurement of the beam profile is an essential factor of the beam study.

  20. Nuclear structure studies with gamma-ray beams

    SciTech Connect

    Tonchev, Anton; Bhatia, Chitra; Kelley, John; Raut, Rajarshi; Rusev, Gencho; Tornow, Werner; Tsoneva, Nadia

    2015-05-28

    In stable and weakly bound neutron-rich nuclei, a resonance-like concentration of dipole states has been observed for excitation energies below the neutron-separation energy. This clustering of strong dipole states has been named the Pygmy Dipole Resonance (PDR) in contrast to the Giant Dipole Resonance (GDR) that dominates the E1 response. Understanding the PDR is presently of great interest in nuclear structure and nuclear astrophysics. High-sensitivity studies of E1 and M1 transitions in closed-shell nuclei using monoenergetic and 100% linearly-polarized photon beams are presented.

  1. Identifying nonlinear biomechanical models by multicriteria analysis

    NASA Astrophysics Data System (ADS)

    Srdjevic, Zorica; Cveticanin, Livija

    2012-02-01

    In this study, the methodology developed by Srdjevic and Cveticanin (International Journal of Industrial Ergonomics 34 (2004) 307-318) for the nonbiased (objective) parameter identification of the linear biomechanical model exposed to vertical vibrations is extended to the identification of n-degree of freedom (DOF) nonlinear biomechanical models. The dynamic performance of the n-DOF nonlinear model is described in terms of response functions in the frequency domain, such as the driving-point mechanical impedance and seat-to-head transmissibility function. For randomly generated parameters of the model, nonlinear equations of motion are solved using the Runge-Kutta method. The appropriate data transformation from the time-to-frequency domain is performed by a discrete Fourier transformation. Squared deviations of the response functions from the target values are used as the model performance evaluation criteria, thus shifting the problem into the multicriteria framework. The objective weights of criteria are obtained by applying the Shannon entropy concept. The suggested methodology is programmed in Pascal and tested on a 4-DOF nonlinear lumped parameter biomechanical model. The identification process over the 2000 generated sets of parameters lasts less than 20 s. The model response obtained with the imbedded identified parameters correlates well with the target values, therefore, justifying the use of the underlying concept and the mathematical instruments and numerical tools applied. It should be noted that the identified nonlinear model has an improved accuracy of the biomechanical response compared to the accuracy of a linear model.

  2. Nuclear Structure Studies with Stable and Radioactive Beams: The SPES radioactive ion beam project

    NASA Astrophysics Data System (ADS)

    de Angelis, G.; SPES Collaboration; Prete, G.; Andrighetto, A.; Manzolaro, M.; Corradetti, S.; Scarpa, D.; Rossignoli, M.; Monetti, A.; Lollo, M.; Calderolla, M.; Vasquez, J.; Zafiropoulos, D.; Sarchiapone, L.; Benini, D.; Favaron, P.; Rigato, M.; Pegoraro, R.; Maniero, D.; Calabretta, L.; Comunian, M.; Maggiore, M.; Lombardi, A.; Piazza, L.; Porcellato, A. M.; Roncolato, C.; Bisoffi, G.; Pisent, A.; Galatà, A.; Giacchini, M.; Bassato, G.; Canella, S.; Gramegna, F.; Valiente, J.; Bermudez, J.; Mastinu, P. F.; Esposito, J.; Wyss, J.; Russo, A.; Zanella, S.

    2015-04-01

    A new Radioactive Ion Beam (RIB) facility (SPES) is presently under construction at the Legnaro National Laboratories of INFN. The SPES facility is based on the ISOL method using an UCx Direct Target able to sustain a power of 10 kW. The primary proton beam is provided by a high current Cyclotron accelerator with energy of 35-70 MeV and a beam current of 0.2-0.5 mA. Neutron-rich radioactive ions are produced by proton induced fission on an Uranium target at an expected fission rate of the order of 1013 fissions per second. After ionization and selection the exotic isotopes are re-accelerated by the ALPI superconducting LINAC at energies of 10A MeV for masses in the region A=130 amu. The expected secondary beam rates are of the order of 107 - 109 pps. Aim of the SPES facility is to deliver high intensity radioactive ion beams of neutron rich nuclei for nuclear physics research as well as to be an interdisciplinary research centre for radio-isotopes production for medicine and for neutron beams.

  3. Developmental biomechanics of the human cervical spine.

    PubMed

    Nuckley, David J; Linders, David R; Ching, Randal P

    2013-04-05

    Head and neck injuries, the leading cause of death for children in the U.S., are difficult to diagnose, treat, and prevent because of a critical void in our understanding of the biomechanical response of the immature cervical spine. The objective of this study was to investigate the functional and failure biomechanics of the cervical spine across multiple axes of loading throughout maturation. A correlational study design was used to examine the relationships governing spinal maturation and biomechanical flexibility curves and tolerance data using a cadaver human in vitro model. Eleven human cadaver cervical spines from across the developmental spectrum (2-28 years) were dissected into segments (C1-C2, C3-C5, and C6-C7) for biomechanical testing. Non-destructive flexibility tests were performed in tension, compression, flexion, extension, lateral bending, and axial rotation. After measuring their intact biomechanical responses, each segment group was failed in different modes to measure the tissue tolerance in tension (C1-C2), compression (C3-C5), and extension (C5-C6). Classical injury patterns were observed in all of the specimens tested. Both the functional (p<0.014) and failure (p<0.0001) mechanics exhibited significant relationships with age. Nonlinear flexibility curves described the functional response of the cervical spine throughout maturation and elucidated age, spinal level, and mode of loading specificity. These data support our understanding of the child cervical spine from a developmental perspective and facilitate the generation of injury prevention or management schema for the mitigation of child spine injuries and their deleterious effects.

  4. High-spin nuclear structure studies with radioactive ion beams

    SciTech Connect

    Baktash, C.

    1992-12-31

    Two important developments in the sixties, namely the advent of heavy-ion accelerators and fabrication of Ge detectors, opened the way for the experimental studies of nuclear properties at high angular momentum. Addition of a new degree of freedom, namely spin, made it possible to observe such fascinating phenomena as occurrences and coexistence of a variety of novel shapes, rise, fall and occasionally rebirth of nuclear collectivity, and disappearance of pairing correlations. Today, with the promise of development of radioactive ion beams (RIB) and construction of the third-generation Ge-detection systems (GAMMASPHERE and EUROBALL), the authors are poised to explore new and equally fascinating phenomena that have been hitherto inaccessible. With the addition of yet another dimension, namely the isospin, they will be able to observe and verify predictions for exotic shapes as varied as rigid triaxiality, hyperdeformation and triaxial octupole shapes, or to investigate the T = 0 pairing correlations. In this paper, they shall review, separately for neutron-deficient and neutron-rich nuclei, these and a few other new high-spin physics opportunities that may be realized with RIB. Following this discussion, they shall present a list of the beam species, intensities and energies that are needed to fulfill these goals. The paper will conclude with a description of the experimental techniques and instrumentations that are required for these studies.

  5. Study of Synchrotron Radiation for the Electron Beam Polarimeter for the MEIC

    SciTech Connect

    Sullivan, M.

    2015-08-06

    This is a look at the synchrotron radiation coming from the chicane in the electron beam line for the MEIC design. The power density on the beam pipe as well as transmission through the beam pipe is studied. The optics design is version 12.

  6. Studies of Limits on Uncontrolled Heavy Ion Beam Losses for Allowing Hands-On Maintenance

    SciTech Connect

    Reginald M. Ronningen; Igor Remec

    2010-09-11

    Dose rates from accelerator components activated by 1 W/m beam losses are obtained semiempirically for a 1 GeV proton beam and by use of Monte Carlo transport codes for the proton beam and for 777 MeV/u 3He, 500 MeV/u 48Ca, 86Kr, 136Xe, and 400 MeV/u 238U ions. The dose rate obtained by the semi-empirical method, 0.99 mSv/h (99 mrem/h) at 30 cm, 4 h after 100 d irradiation by a 1-GeV proton beam, is consistent with studies at several accelerator facilities and with adopted hands-on maintenance dose rate limits. Monte Carlo simulations verify this result for protons and extend studies to heavy ion beam losses in drift-tube linac and superconducting linac accelerating structures. The studies indicate that the 1 W/m limit imposed on uncontrolled beam losses for high-energy proton beams might be relaxed for heavy ion beams. These studies further suggest that using the ratio of neutrons produced by a heavy ion beam to neutrons produced by a proton beam along with the dose rate from the proton beam (for thin-target scenarios) should allow an estimate of the dose rates expected from heavy ion beam losses.

  7. Simulation study of interactions of Space Shuttle-generated electron beams with ambient plasmas

    NASA Technical Reports Server (NTRS)

    Lin, Chin S.

    1992-01-01

    This report summarizes results obtained through the support of NASA Grant NAGW-1936. The objective of this report is to conduct large scale simulations of electron beams injected into space. The topics covered include the following: (1) simulation of radial expansion of an injected electron beam; (2) simulations of the active injections of electron beams; (3) parameter study of electron beam injection into an ionospheric plasma; and (4) magnetosheath-ionospheric plasma interactions in the cusp.

  8. Laboratory studies of the charge neutralization of a rocket payload during electron beam emission

    NASA Technical Reports Server (NTRS)

    Bernstein, W.; Whalen, B. A.; Harris, F. R.; Mcnamara, A. G.; Konradi, A.

    1980-01-01

    The charge neutralization of an electrically-isolated rocket payload emitting an energetic electron beam has been studied in experiments in the large vacuum chamber at Johnson Space Center. The introduction of an RF-discharge-produced ambient plasma density (10,000 to 50,000 per cu cm) reduces the payload potential to 200 V for low current (1 and 10 ma) beams. The ignition of the beam-plasma discharge provides an efficient neutralization process for higher current beams.

  9. Suspension biomechanics of swimming microbes

    PubMed Central

    Ishikawa, Takuji

    2009-01-01

    Micro-organisms play a vital role in many biological, medical and engineering phenomena. Some recent research efforts have demonstrated the importance of biomechanics in understanding certain aspects of micro-organism behaviours such as locomotion and collective motions of cells. In particular, spatio-temporal coherent structures found in a bacterial suspension have been the focus of many research studies over the last few years. Recent studies have shown that macroscopic properties of a suspension, such as rheology and diffusion, are strongly affected by meso-scale flow structures generated by swimming microbes. Since the meso-scale flow structures are strongly affected by the interactions between microbes, a bottom-up strategy, i.e. from a cellular level to a continuum suspension level, represents the natural approach to the study of a suspension of swimming microbes. In this paper, we first provide a summary of existing biomechanical research on interactions between a pair of swimming micro-organisms, as a two-body interaction is the simplest many-body interaction. We show that interactions between two nearby swimming micro-organisms are described well by existing mathematical models. Then, collective motions formed by a group of swimming micro-organisms are discussed. We show that some collective motions of micro-organisms, such as coherent structures of bacterial suspensions, are satisfactorily explained by fluid dynamics. Lastly, we discuss how macroscopic suspension properties are changed by the microscopic characteristics of the cell suspension. The fundamental knowledge we present will be useful in obtaining a better understanding of the behaviour of micro-organisms. PMID:19674997

  10. Androgen deprivation causes selective deficits in the biomechanical leg muscle function of men during walking: a prospective case–control study

    PubMed Central

    Cheung, Ada S.; Gray, Hans; Schache, Anthony G.; Hoermann, Rudolf; Lim Joon, Daryl; Zajac, Jeffrey D.; Pandy, Marcus G.

    2016-01-01

    Abstract Background Although muscle mass declines with testosterone deficiency in men, previous studies of muscle function have not demonstrated consistent deficits, likely due to relatively insensitive methodology. Our objective was to determine the effects of testosterone deprivation on the biomechanical function of individual lower‐limb muscles. Methods We conducted a 12‐month prospective, observational case–control study of 34 men newly commencing androgen deprivation treatment (ADT) for prostate cancer and 29 age‐matched prostate cancer controls. Participants were assessed at 0, 6, and 12 months while walking in a biomechanics laboratory. We combined video‐based motion capture and ground reaction force data with computerized musculoskeletal modelling to assess the following primary outcomes: (i) peak joint torques at the hip, knee and ankle, and corresponding individual muscle forces; (ii) individual muscle contributions to acceleration of the body's centre of mass; and (iii) walking speed, stride length, and step width. A linear mixed model was used to compare mean differences between groups. Results Compared with controls over 12 months, men receiving ADT had a mean reduction in total testosterone level from 14.1 to 0.4 nmol/L, and demonstrated more marked decreases in peak hip flexor torque by 14% [mean difference −0.11 N/kg (−0.19, −0.03), P = 0.01] and peak knee extensor torque by 16% [−0.11 N/kg (−0.20, −0.02), P = 0.02] of the initial mean value. Correspondingly, iliopsoas force decreased by 14% (P = 0.006), and quadriceps force decreased by 11%, although this narrowly missed statistical significance (P = 0.07). Soleus decreased contribution to forward acceleration of the body's centre of mass by 17% [mean difference −0.17 m/s2 (−0.29, −0.05), P < 0.01]. No significant changes between groups were observed in other joint torques or individual muscle contributions to acceleration of the body

  11. Energy deposition studies for the LBNE beam absorber

    SciTech Connect

    Rakhno, Igor L.; Mokhov, Nikolai V.; Tropin, Igor S.

    2015-01-29

    Results of detailed Monte Carlo energy deposition studies performed for the LBNE absorber core and the surrounding shielding with the MARS15 code are described. The model of the entire facility, that includes a pion-production target, focusing horns, target chase, decay channel, hadron absorber system – all with corresponding radiation shielding – was developed using the recently implemented ROOT-based geometry option in the MARS15 code. This option provides substantial flexibility and automation when developing complex geometry models. Both normal operation and accidental conditions were studied. Various design options were considered, in particular the following: (i) filling the decay pipe with air or helium; (ii) the absorber mask material and shape; (iii) the beam spoiler material and size. Results of detailed thermal calculations with the ANSYS code helped to select the most viable absorber design options.

  12. Experimental studies to test simple flexural neutralizers fitted to beams

    NASA Astrophysics Data System (ADS)

    Clark, P.; White, R. G.

    1994-10-01

    The control of vibration in one-dimensional structures is of considerable interest in practical engineering. With the majority of industrial machinery installations, it is this type of structure, for example, beams, pipework vibrating at low frequencies and other mechanical linkages, which forms one of the main vibration paths that bypass isolator systems. It is of interest to consider discontinuities that may be incorporated into these types of structure since they significantly affect the vibration characteristics of the complete installation. One such discontinuity that may be employed in vibration control is the vibration neutralizer. Previous work in this area of research has developed theoretical models of the neutralizer performance as a vibration control technique with particular reference to the effect of incorporating alternative mounting methods. In this work, complementary experimental studies are presented with a view to validating those theoretical studies previously undertaken.

  13. Biomechanics as a window into the neural control of movement.

    PubMed

    Latash, Mark L

    2016-09-01

    Biomechanics and motor control are discussed as parts of a more general science, physics of living systems. Major problems of biomechanics deal with exact definition of variables and their experimental measurement. In motor control, major problems are associated with formulating currently unknown laws of nature specific for movements by biological objects. Mechanics-based hypotheses in motor control, such as those originating from notions of a generalized motor program and internal models, are non-physical. The famous problem of motor redundancy is wrongly formulated; it has to be replaced by the principle of abundance, which does not pose computational problems for the central nervous system. Biomechanical methods play a central role in motor control studies. This is illustrated with studies with the reconstruction of hypothetical control variables and those exploring motor synergies within the framework of the uncontrolled manifold hypothesis. Biomechanics and motor control have to merge into physics of living systems, and the earlier this process starts the better.

  14. Minicomputer For Biomechanical Research

    NASA Astrophysics Data System (ADS)

    Shierman, Gail; Rhymes, Tom

    1982-02-01

    The increased capabilities of minicomputers today allows a biomechanics laboratory to establish a self-contained computer system for a reasonable price. The system includes a microprocessor, a printer and a CRT. Analog to digital conversion is an important feature to consider as well as the ability to interface with a mainframe computer. A minicomputer adapted for film analysis should be a consideration for data analysis when developing a cinematography laboratory. For the past 10-15 years the area of biomechanics has enjoyed the advances in technology. Equipment and instrumentation once used exclusively by engineers and physicists have become readily available to those involved with snorts analyses. Among the various pieces of equipment accessible to biomechanists today, probably the most important one is the computer. At this time several biomechanics laboratories are using the computer to analyze kinematic and kinetic data obtained from film. The computer in use at each school is generally the main University or College computer with a remote terminal set-up in the biomechanics laboratory. This system functions well if there is adequate response from the time-sharing system of the main computer, and if there is at least one knowledgeable technician available. With the trend toward minicomputers today, their increased capabilities, and their ease of use, a self-contained minicomputer system in the biomechanics laboratory appears to be a viable alternative. The computer system in use in the ,Biomechanics Laboratory at the University of Oklahoma is based around the Cromemco Z2D computer connected to a PCD motion analyzer (Figure 1). The data acquisition system consists of the eight-bit microprocessor-based minicomputer connected to an analog to digital converter (ADC). As a terminal for the computer, we have either a video display unit or a Model 43 Teletype. The Model 43 provides a hard copy out-put while the video terminal provides much faster I/O, useful for

  15. Role of Aquaporin 0 in lens biomechanics

    SciTech Connect

    Sindhu Kumari, S.; Gupta, Neha; Shiels, Alan; FitzGerald, Paul G.; Menon, Anil G.; Mathias, Richard T.; Varadaraj, Kulandaiappan

    2015-07-10

    Maintenance of proper biomechanics of the eye lens is important for its structural integrity and for the process of accommodation to focus near and far objects. Several studies have shown that specialized cytoskeletal systems such as the beaded filament (BF) and spectrin-actin networks contribute to mammalian lens biomechanics; mutations or deletion in these proteins alters lens biomechanics. Aquaporin 0 (AQP0), which constitutes ∼45% of the total membrane proteins of lens fiber cells, has been shown to function as a water channel and a structural cell-to-cell adhesion (CTCA) protein. Our recent ex vivo study on AQP0 knockout (AQP0 KO) mouse lenses showed the CTCA function of AQP0 could be crucial for establishing the refractive index gradient. However, biomechanical studies on the role of AQP0 are lacking. The present investigation used wild type (WT), AQP5 KO (AQP5{sup −/−}), AQP0 KO (heterozygous KO: AQP0{sup +/−}; homozygous KO: AQP0{sup −/−}; all in C57BL/6J) and WT-FVB/N mouse lenses to learn more about the role of fiber cell AQPs in lens biomechanics. Electron microscopic images exhibited decreases in lens fiber cell compaction and increases in extracellular space due to deletion of even one allele of AQP0. Biomechanical assay revealed that loss of one or both alleles of AQP0 caused a significant reduction in the compressive load-bearing capacity of the lenses compared to WT lenses. Conversely, loss of AQP5 did not alter the lens load-bearing ability. Compressive load-bearing at the suture area of AQP0{sup +/−} lenses showed easy separation while WT lens suture remained intact. These data from KO mouse lenses in conjunction with previous studies on lens-specific BF proteins (CP49 and filensin) suggest that AQP0 and BF proteins could act co-operatively in establishing normal lens biomechanics. We hypothesize that AQP0, with its prolific expression at the fiber cell membrane, could provide anchorage for cytoskeletal structures like BFs and

  16. Experimental study of the stability of a neutralized electron beam

    SciTech Connect

    Kudelainen, V.I.; Parkhomchuk, V.V.; Pestrikov, D.V.

    1983-05-01

    Results are reported from measurements of the spectral properties of a long neutralized electron beam in the NAP-M proton storage ring. It is shown that when the number of secondary electrons is small, both the longitudinal and the transverse oscillations are strongly damped, so that beam instability is suppressed. The current density of the neutralized electron beam produced in the experiments was approx.10/sup 2/ times greater than the theoretical value determined from the instability threshold for nonaxisymmetric oscillations.

  17. Study on electron beam in a low energy plasma focus

    SciTech Connect

    Khan, Muhammad Zubair; Ling, Yap Seong; San, Wong Chiow

    2014-03-05

    Electron beam emission was investigated in a low energy plasma focus device (2.2 kJ) using copper hollow anode. Faraday cup was used to estimate the energy of the electron beam. XR100CR X-ray spectrometer was used to explore the impact of the electron beam on the target observed from top-on and side-on position. Experiments were carried out at optimized pressure of argon gas. The impact of electron beam is exceptionally notable with two different approaches using lead target inside hollow anode in our plasma focus device.

  18. Radiographic, biomechanical, and histological evaluation of rhBMP-2 in a 3-level intertransverse process spine fusion: an ovine study.

    PubMed

    Toth, Jeffrey M; Wang, Mei; Lawson, Joshua; Badura, Jeffrey M; DuBose, Kimberly Bailey

    2016-12-01

    OBJECTIVE The objective of this study was to evaluate bone grafts consisting of rhBMP-2 on an absorbable collagen sponge with a ceramic composite bulking agent, rhBMP-2, directly on a ceramic-collagen sponge carrier or iliac crest bone graft (ICBG) in combination with local bone graft to effect fusion in a multisegmental instrumented ovine lumbar intertransverse process fusion model. METHODS Thirty-six sheep had a single treatment at 3 spinal levels in both the right and left intertransverse process spaces. Group 1 sheep were treated with 7.5 cm(3) of autograft consisting of ICBG plus local bone for each intertransverse process space. For Groups 2-4, 4 cm(3) of local bone was placed within the intertransverse process space followed by 4.5-5 cm(3) of the rhBMP-2 graft material. Group 2 animals received 1.5 mg/cm(3) rhBMP-2 on an absorbable collagen sponge with a commercial bone void filler consisting of Type I lyophilized collagen with a biphasic hydroxyapatite/β-tricalcium phosphate ceramic with local bone. Group 3 animals received 0.75 mg/m cm(3) of rhBMP-2 on a collagen ceramic sponge carrier with local bone. Group 4 animals received 1.35 mg/cm(3) of rhBMP-2 on the same collagen ceramic sponge carrier with local bone. Sheep were euthanized 6 months postoperatively. Manual palpation, biomechanical testing, CT, radiography, and undecalcified histology were performed to assess the presence of fusion associated with the treatments. RESULTS All animals in Groups 2-4 that received grafts containing rhBMP-2 achieved radiographic and CT fusion at all 3 levels. In Group 1 (bone autograft alone), only 19% of the levels demonstrated radiographic fusion, 14% resulted in possible radiographic fusion, and 67% of the levels demonstrated radiographic nonfusion. Biomechanical testing showed that Groups 2-4 demonstrated similar stiffness of the L2-5 segment in all 6 loading directions, with each of the 3 groups having significantly greater stiffness than the autograft-only group

  19. Effects of Suture Choice on Biomechanics and Physeal Status After Bioenhanced Anterior Cruciate Ligament Repair in Skeletally Immature Patients: A Large-Animal Study

    PubMed Central

    Vavken, Patrick; Proffen, Benedikt; Peterson, Chris; Fleming, Braden C.; Machan, Jason T.; Murray, Martha M.

    2012-01-01

    Purpose The objective of this study was to assess the effect of absorbable or nonabsorbable sutures in bioenhanced anterior cruciate ligament (ACL) repair in a skeletally immature pig model on suture tunnel and growth plate healing and biomechanical outcomes. Methods Sixteen female skeletally immature Yorkshire pigs were randomly allocated to receive unilateral, bioenhanced ACL repair with an absorbable (Vicryl) or nonabsorbable (Ethibond) suture augmented by an extracellular matrix-based scaffold (MIACH). After 15 weeks of healing, micro–computed tomography was used to measure residual tunnel diameters and growth plate status, and biomechanical outcomes were assessed. Results At 15 weeks postoperatively, there was a significant difference in tunnel diameter with significantly larger diameters in the nonabsorbable suture group (4.4 ± 0.3 mm; mean ± SD) than in the absorbable group (1.8 ± 0.5 mm; P <.001). The growth plate showed a significantly greater affected area in the nonabsorbable group (15.2 ± 3.4 mm2) than in the absorbable group (2.7 ± 0.8 mm2, P < .001). There was no significant difference in the linear stiffness of the repairs (29.0 ± 14.8 N/mm for absorbable v 43.3 ± 28.3 N/mm for nonabsorbable sutures, P = .531), but load to failure was higher in the nonabsorbable suture group (211 ± 121.5 N) than in the absorbable suture group (173 ± 101.4 N, P =.002). There was no difference between the 2 groups in anteroposterior laxity at 30° (P = .5117), 60° (P = .3150), and 90° (P = .4297) of knee flexion. Conclusions The use of absorbable sutures for ACL repair resulted in decreased physeal plate damage after 15 weeks of healing; however, use of nonabsorbable sutures resulted in 20% stronger repairs. Clinical Relevance Choice of suture type for ACL repair or repair of tibial avulsion fractures may depend on patient skeletal age and size, with absorbable sutures preferred in very young, small patients at higher risk with physeal damage and

  20. Study of nanoscale structural biology using advanced particle beam microscopy

    NASA Astrophysics Data System (ADS)

    Boseman, Adam J.

    This work investigates developmental and structural biology at the nanoscale using current advancements in particle beam microscopy. Typically the examination of micro- and nanoscale features is performed using scanning electron microscopy (SEM), but in order to decrease surface charging, and increase resolution, an obscuring conductive layer is applied to the sample surface. As magnification increases, this layer begins to limit the ability to identify nanoscale surface structures. A new technology, Helium Ion Microscopy (HIM), is used to examine uncoated surface structures on the cuticle of wild type and mutant fruit flies. Corneal nanostructures observed with HIM are further investigated by FIB/SEM to provide detailed three dimensional information about internal events occurring during early structural development. These techniques are also used to reconstruct a mosquito germarium in order to characterize unknown events in early oogenesis. Findings from these studies, and many more like them, will soon unravel many of the mysteries surrounding the world of developmental biology.

  1. Intra-beam scattering studies for low emittance at BAPS

    NASA Astrophysics Data System (ADS)

    Tian, Sai-Ke; Wang, Jiu-Qing; Xu, Gang; Jiao, Yi

    2015-06-01

    The target parameters of modern ultra-low emittance storage ring light sources are entering into a regime where intra-beam scattering (IBS) becomes important and, in the case of the Beijing Advanced Photon Source (BAPS), which is being designed at the Institute of High Energy Physics (IHEP), even a limitation for achieving the desired emittances in both transverse planes at the diffraction limit for X-ray wavelengths (≈10 pm). Due to the low emittance, the IBS effect will be very strong. Accurate calculations are needed to check if the design goal (ɛh+ɛv = 20 pm) can be reached. In this paper, we present the results of numerical simulation studies of the IBS effect on a BAPS temporary design lattice.

  2. Direct reaction experimental studies with beams of radioactive tin ions

    SciTech Connect

    Jones, K. L. Ayres, A.; Bey, A.; Burcher, S.; Cartegni, L.; Cerizza, G.; Ahn, S.; Allmond, J. M.; Beene, J. R.; Galindo-Uribarri, A.; Liang, J. F.; Nesaraja, C. D.; Pain, S. D.; Radford, D. C.; Schmitt, K. T.; Smith, M. S.; Stracener, D. W.; Varner, R. L.; Bardayan, D. W.; Baugher, T.; and others

    2015-10-15

    The tin chain of isotopes provides a unique region in which to investigate the evolution of single-particle structure, spreading from N = 50 at {sup 100}Sn, through 10 stable isotopes and the N = 82 shell closure at {sup 132}Sn out into the r-process path. Direct reactions performed on radioactive ion beams are sensitive spectroscopic tools for studying exotic nuclei. Here we present one experiment knocking out neutrons from tin isotopes that are already neutron deficient and two reactions that add a neutron to neutron-rich {sup 130}Sn. Both techniques rely on selective particle identification and the measurement of γ rays in coincidence with charged ions. We present the goals of the two experiments and the particle identification for the channels of interest. The final results will be presented in future publications.

  3. Diagnostic studies of ion beam formation in inductively coupled plasma

    SciTech Connect

    Jacobs, Jenee L.

    2015-01-01

    This dissertation describes a variety of studies focused on the plasma and the ion beam in inductively coupled plasma mass spectrometry (ICP-MS). The ability to use ICP-MS for measurements of trace elements in samples requires the analytes to be efficiently ionized. Updated ionization efficiency tables are discussed for ionization temperatures of 6500 K and 7000 K with an electron density of 1 x 1015 cm-3. These values are reflective of the current operating parameters of ICP-MS instruments. Calculations are also discussed for doubly charged (M2+) ion formation, neutral metal oxide (MO) ionization, and metal oxide (MO+) ion dissociation for similar plasma temperature values. Ionization efficiency results for neutral MO molecules in the ICP have not been reported previously.

  4. Comments on Injector Proton Beam Study in Run 2014

    SciTech Connect

    Zhang, S. Y.

    2014-09-15

    During the entire period of injector proton study in run 2014, it seems that the beam transverse emittance out of Booster is larger than that in run 2013. The emittance measured at the BtA transfer line and also the transmission from Booster late to AGS late are presented for this argument. In addition to this problem, it seems that the multiturn Booster injection, which defines the transverse emittance, needs more attention. Moreover, for high intensity operations, the space charge effect may be already relevant in RHIC polarized proton runs. With the RHIC proton intensity improvement in the next several years, higher Booster input intensity is needed, therefore, the space charge effect at the Booster injection and early ramp may become a new limiting factor.

  5. Direct Reaction Experimental Studies with Beams of Radioactive Tin Ions

    SciTech Connect

    Jones, K. L.; Ahn, S.H.; Allmond, James M; Ayres, A.; Bardayan, Daniel W; Baugher, T.; Bazin, D.; Beene, James R; Berryman, J. S.; Bey, A.; Bingham, C. R.; Cartegni, L.; Chae, K. Y.; Gade, A.; Galindo-Uribarri, Alfredo {nmn}; Garcia-Ruiz, R.F.; Grzywacz, Robert Kazimierz; Howard, Meredith E; Kozub, R. L.; Liang, J Felix; Manning, Brett M; Matos, M.; McDaniel, S.; Miller, D.; Nesaraja, Caroline D; O'Malley, Patrick; Padgett, S; Padilla-Rodal, Elizabeth; Pain, Steven D; Pittman, S. T.; Radford, David C; Ratkiewicz, Andrew J; Schmitt, Kyle; Smith, Michael Scott; Stracener, Daniel W; Stroberg, S.; Tostevin, Jeffrey A; Varner Jr, Robert L; Weisshaar, D.; Wimmer, K.

    2015-01-01

    The tin chain of isotopes provides a unique region in which to investigate the evolution of single-particle structure, spreading from N = 50 at Sn-100, through 10 stable isotopes and the N = 82 shell closure at Sn-132 out into the r-process path. Direct reactions performed on radioactive ion beams are sensitive spectroscopic tools for studying exotic nuclei. Here we present one experiment knocking out neutrons from tin isotopes that are already neutron deficient and two reactions that add a neutron to neutron-rich Sn-130. Both techniques rely on selective particle identification and the measurement of gamma rays in coincidence with charged ions. We present the goals of the two experiments and the particle identification for the channels of interest. The final results will be presented in future publications.

  6. Radiological Studies for the LCLS Beam Abort System

    SciTech Connect

    Santana Leitner, M.; Vollaire, J.; Mao, X.S.

    2008-03-25

    The Linac Coherent Light Source (LCLS), a pioneer hard x-ray free electron laser is currently under construction at the Stanford Linear Accelerator Center. It is expected that by 2009 LCLS will deliver laser pulses of unprecedented brightness and short length, which will be used in several forefront research applications. This ambitious project encompasses major design challenges to the radiation protection like the numerous sources and the number of surveyed objects. In order to sort those, the showers from various loss sources have been tracked along a detailed model covering 1/2 mile of LCLS accelerator by means of the Monte Carlo intra nuclear cascade codes FLUKA and MARS15. This article covers the FLUKA studies of heat load; prompt and residual dose and environmental impact for the LCLS beam abort system.

  7. Cartesian beams.

    PubMed

    Bandres, Miguel A; Gutiérrez-Vega, Julio C

    2007-12-01

    A new and very general beam solution of the paraxial wave equation in Cartesian coordinates is presented. We call such a field a Cartesian beam. The complex amplitude of the Cartesian beams is described by either the parabolic cylinder functions or the confluent hypergeometric functions, and the beams are characterized by three parameters that are complex in the most general situation. The propagation through complex ABCD optical systems and the conditions for square integration are studied in detail. Applying the general expression of the Cartesian beams, we also derive two new and meaningful beam structures that, to our knowledge, have not yet been reported in the literature. Special cases of the Cartesian beams are the standard, elegant, and generalized Hermite-Gauss beams, the cosine-Gauss beams, the Lorentz beams, and the fractional order beams.

  8. Measurement Techniques for Cellular Biomechanics In Vitro

    PubMed Central

    Addae-Mensah, Kweku A; Wikswo, John P

    2014-01-01

    Living cells and tissues experience mechanical forces in their physiological environments that are known to affect many cellular processes. Also of importance are the mechanical properties of cells, as well as the microforces generated by cellular processes themselves in their microenvironments. The difficulty associated with studying these phenomena in vivo has led to alternatives such as using in vitro models. The need for experimental techniques for investigating cellular biomechanics and mechanobiology in vitro has fueled an evolution in the technology used in these studies. Particularly noteworthy are some of the new biomicroelectromechanical systems (BioMEMs) devices and techniques that have been introduced to the field. We describe some of the cellular micromechanical techniques and methods that have been developed for in vitro studies, and provide summaries of the ranges of measured values of various biomechanical quantities. We also briefly address some of our experiences in using these methods and include modifications we have introduced in order to improve them. PMID:18445766

  9. Biomechanics of the sclera and effects on intraocular pressure

    PubMed Central

    Jia, Xu; Yu, Juan; Liao, Sheng-Hui; Duan, Xuan-Chu

    2016-01-01

    Accumulating evidence indicates that glaucoma is a multifactorial neurodegenerative disease characterized by the loss of retinal ganglion cells (RGC), resulting in gradual and progressive permanent loss of vision. Reducing intraocular pressure (IOP) remains the only proven method for preventing and delaying the progression of glaucomatous visual impairment. However, the specific role of IOP in optic nerve injury remains controversial, and little is known about the biomechanical mechanism by which elevated IOP leads to the loss of RGC. Published studies suggest that the biomechanical properties of the sclera and scleral lamina cribrosa determine the biomechanical changes of optic nerve head, and play an important role in the pathologic process of loss of RGC and optic nerve damage. This review focuses on the current understanding of biomechanics of sclera in glaucoma and provides an overview of the possible interactions between the sclera and IOP. Treatments and interventions aimed at the sclera are also discussed. PMID:28003987

  10. Experimental beam system studies of plasma-polymer interactions

    NASA Astrophysics Data System (ADS)

    Nest, Dustin George

    Since the invention of the integrated circuit, the semiconductor industry has relied on the shrinking of device dimensions to increase device performance and decrease manufacturing costs. However, the high degree of roughening observed during plasma etching of current generation photoresist (PR) polymers can result in poor pattern transfer and ultimately decreased device performance or failure. Plasma-surface interactions are inherently difficult to study due to the highly coupled nature of the plasma enviroment. To better understand these interactions, a beam system approach is employed where polymers are exposed to beams of ions and vacuum ultraviolet (VUV) photons. Through the use of the beam system approach, simultaneous VUV radiation, ion bombardment, and moderate substrate heating have been identified as key elements, acting synergistically, as being responsible for roughening of current generation 193 nm PR during plasma processing. Sequential exposure is not adequate for the development of surface roughness, as observed through AFM and SEM. Ion bombardment results in the formation of a graphitized near-surface region with a depth of a few nanometers, the expected ion penetration depth of 150 eV argon ions. In contrast, VUV radiation results in the loss of carbon-oxygen bonds in the bulk PR as observed through Transmission FTIR. Based on the differing penetration depth of either ions or photons, their resulting chemical modifications, and the temperature dependence of the observed roughening, a mechanism is proposed based on stress relaxation resulting in surface buckling. The surface roughness of poly(4-methyl styrene) (P4MS) and poly(alpha-methyl styrene) (PalphaMS) have also been investigated under exposure to ions and VUV photons. PaMS degrades during VUV radiation above its ceiling temperature of ˜60°C. Despite having the same chemical composition as PalphaMS, P4MS does not degrade during VUV exposure at 70°C due to its relatively high ceiling

  11. Inside-Out or Outside-In Suturing Should Not Be Considered the Standard Repair Method for Radial Tears of the Midbody of the Lateral Meniscus: A Systematic Review and Meta-Analysis of Biomechanical Studies.

    PubMed

    Alentorn-Geli, Eduard; Choi, J H James; Stuart, Joseph J; Toth, Alison P; Garrett, William E; Taylor, Dean C; Moorman, Claude T

    2016-10-01

    The purpose was to evaluate which meniscal repair technique for radial tears of the midbody of the lateral meniscus demonstrates the best biomechanical properties. An electronic literature search was conducted using PubMed, EMBASE, CINAHL, and ScienceDirect databases. Biomechanical studies investigating the repair characteristics of radial tears in the midbody of the lateral meniscus were included. After appropriate screening, a total of 54 studies were reviewed in detail (full text), and 6 met inclusion criteria. The most common cause of exclusion was the investigation of longitudinal tears. Only two studies could be meta-analyzed. Stiffness was significantly higher for all-inside compared with inside-out repair techniques (p = 0.0009). No significant differences were observed between both suture methods for load to failure (p = 0.45). However, both studies used different all-inside devices and suture constructs. No clear conclusions can be drawn from the comparison of both types of repairs for displacement, site of failure, or contact pressure changes. Overall, there are no conclusive data to suggest that inside-out or outside-in suture repair has better load to failure or stiffness, less displacement, or different site of failure compared with all-inside repair. According to biomechanical data, it is under surgeon's preference to elect one repair technique over the other.

  12. Beam Simulation Studies of the LEBT for RIA Driver Linac

    SciTech Connect

    Zhao, Q.; Wu, X.; Andreev, V.; Balabin, A.; Doleans, M.; Gorelov, D.; Grimm, T.L.; Hartung, W.; Marti, F.; Schriber, S.O.; York, R.C.; Leitner, D.; Lyneis, C.M.

    2005-03-15

    The low energy beam transport (LEBT) system in the front-end of the Rare Isotope Accelerator (RIA) uses a 70 kV platform to pre-accelerate the ion beam from a 30 kV Electron Cyclotron Resonance (ECR) ion source, followed by an achromatic charge selection system. The selected beam is then pre-bunched and matched into the entrance of a Radio Frequency Quadrupole (RFQ) with a multi-harmonic buncher. To meet the beam power requirements for heavy ions, high current (several mA), multi-species beams will be extracted from the ECR. Therefore, it is crucial to control space charge effects in order to obtain the low emittance beam required for RIA. The PARMELA code is used to perform the LEBT simulations for the multi-species beams with 3D space charge calculations. The results of the beam dynamics simulations are presented, and the key issues of emittance growth in the LEBT and its possible compensation are discussed.

  13. Comparative study of beam losses and heat loads reduction methods in MITICA beam source

    SciTech Connect

    Sartori, E. Agostinetti, P.; Dal Bello, S.; Marcuzzi, D.; Serianni, G.; Veltri, P.; Sonato, P.

    2014-02-15

    In negative ion electrostatic accelerators a considerable fraction of extracted ions is lost by collision processes causing efficiency loss and heat deposition over the components. Stripping is proportional to the local density of gas, which is steadily injected in the plasma source; its pumping from the extraction and acceleration stages is a key functionality for the prototype of the ITER Neutral Beam Injector, and it can be simulated with the 3D code AVOCADO. Different geometric solutions were tested aiming at the reduction of the gas density. The parameter space considered is limited by constraints given by optics, aiming, voltage holding, beam uniformity, and mechanical feasibility. The guidelines of the optimization process are presented together with the proposed solutions and the results of numerical simulations.

  14. Comparative study of beam losses and heat loads reduction methods in MITICA beam source

    NASA Astrophysics Data System (ADS)

    Sartori, E.; Agostinetti, P.; Dal Bello, S.; Marcuzzi, D.; Serianni, G.; Sonato, P.; Veltri, P.

    2014-02-01

    In negative ion electrostatic accelerators a considerable fraction of extracted ions is lost by collision processes causing efficiency loss and heat deposition over the components. Stripping is proportional to the local density of gas, which is steadily injected in the plasma source; its pumping from the extraction and acceleration stages is a key functionality for the prototype of the ITER Neutral Beam Injector, and it can be simulated with the 3D code AVOCADO. Different geometric solutions were tested aiming at the reduction of the gas density. The parameter space considered is limited by constraints given by optics, aiming, voltage holding, beam uniformity, and mechanical feasibility. The guidelines of the optimization process are presented together with the proposed solutions and the results of numerical simulations.

  15. Comparative study of beam losses and heat loads reduction methods in MITICA beam source.

    PubMed

    Sartori, E; Agostinetti, P; Dal Bello, S; Marcuzzi, D; Serianni, G; Sonato, P; Veltri, P

    2014-02-01

    In negative ion electrostatic accelerators a considerable fraction of extracted ions is lost by collision processes causing efficiency loss and heat deposition over the components. Stripping is proportional to the local density of gas, which is steadily injected in the plasma source; its pumping from the extraction and acceleration stages is a key functionality for the prototype of the ITER Neutral Beam Injector, and it can be simulated with the 3D code AVOCADO. Different geometric solutions were tested aiming at the reduction of the gas density. The parameter space considered is limited by constraints given by optics, aiming, voltage holding, beam uniformity, and mechanical feasibility. The guidelines of the optimization process are presented together with the proposed solutions and the results of numerical simulations.

  16. Experimental Studies on Behaviour of Reinforced Geopolymer Concrete Beams Subjected to Monotonic Static Loading

    NASA Astrophysics Data System (ADS)

    Madheswaran, C. K.; Ambily, P. S.; Dattatreya, J. K.; Ramesh, G.

    2015-06-01

    This work describes the experimental investigation on behaviour of reinforced GPC beams subjected to monotonic static loading. The overall dimensions of the GPC beams are 250 mm × 300 mm × 2200 mm. The effective span of beam is 1600 mm. The beams have been designed to be critical in shear as per IS:456 provisions. The specimens were produced from a mix incorporating fly ash and ground granulated blast furnace slag, which was designed for a compressive strength of 40 MPa at 28 days. The reinforced concrete specimens are subjected to curing at ambient temperature under wet burlap. The parameters being investigated include shear span to depth ratio (a/d = 1.5 and 2.0). Experiments are conducted on 12 GPC beams and four OPCC control beams. All the beams are tested using 2000 kN servo-controlled hydraulic actuator. This paper presents the results of experimental studies.

  17. Interpreting locomotor biomechanics from the morphology of human footprints.

    PubMed

    Hatala, Kevin G; Wunderlich, Roshna E; Dingwall, Heather L; Richmond, Brian G

    2016-01-01

    Fossil hominin footprints offer unique direct windows to the locomotor behaviors of our ancestors. These data could allow a clearer understanding of the evolution of human locomotion by circumventing issues associated with indirect interpretations of habitual locomotor patterns from fossil skeletal material. However, before we can use fossil hominin footprints to understand better the evolution of human locomotion, we must first develop an understanding of how locomotor biomechanics are preserved in, and can be inferred from, footprint morphologies. In this experimental study, 41 habitually barefoot modern humans created footprints under controlled conditions in which variables related to locomotor biomechanics could be quantified. Measurements of regional topography (depth) were taken from 3D models of those footprints, and principal components analysis was used to identify orthogonal axes that described the largest proportions of topographic variance within the human experimental sample. Linear mixed effects models were used to quantify the influences of biomechanical variables on the first five principal axes of footprint topographic variation, thus providing new information on the biomechanical variables most evidently expressed in the morphology of human footprints. The footprint's overall depth was considered as a confounding variable, since biomechanics may be linked to the extent to which a substrate deforms. Three of five axes showed statistically significant relationships with variables related to both locomotor biomechanics and substrate displacement; one axis was influenced only by biomechanics and another only by the overall depth of the footprint. Principal axes of footprint morphological variation were significantly related to gait type (walking or running), kinematics of the hip and ankle joints and the distribution of pressure beneath the foot. These results provide the first quantitative framework for developing hypotheses regarding the

  18. A study into lowering beam trajectories in P01

    SciTech Connect

    Sondgeroth, A.

    1995-09-01

    This document describes what changes would be needed to lower the primary beams coming from switchyard into enclosure P01 without changing trajectories in the downstream enclosures. There is a 680 foot pipe buried in the ground between Enclosure E and P01 which allows primary beam to travel from the switchyard area to the research division area. This pipe is approximately 25 years old and has started to leak. The effects of the leaky pipe can be catastrophic to the transportation of the proton area beams. The vacuum group has devised an ingenious way of repairing a leak from the inside using remotely controlled grinders, patchers, welders and cameras mounted on carts that can be pulled into the pipe. A typical patch adds approximately one half of an inch of material which, in turn, restricts the aperture of the pipe. This pipe has three separate beams running through it split in the vertical plane. Pwest is the highest beam in the pipe and, in at least one location, the center of the beam clears the top of the pipe by one and one half inches. If a leak were to develop at a low spot in the pipe the patch to fix the leak might create an obstruction for the beam. Hence, the request from the Research Division Head.

  19. Studies on space charge neutralization and emittance measurement of beam from microwave ion source

    SciTech Connect

    Misra, Anuraag; Goswami, A.; Sing Babu, P.; Srivastava, S.; Pandit, V. S. E-mail: vspandit12@gmail.com

    2015-11-15

    A 2.45 GHz microwave ion source together with a beam transport system has been developed at VECC to study the problems related with the injection of high current beam into a compact cyclotron. This paper presents the results of beam profile measurement of high current proton beam at different degrees of space charge neutralisation with the introduction of neon gas in the beam line using a fine leak valve. The beam profiles have been measured at different pressures in the beam line by capturing the residual gas fluorescence using a CCD camera. It has been found that with space charge compensation at the present current level (∼5 mA at 75 keV), it is possible to reduce the beam spot size by ∼34%. We have measured the variation of beam profile as a function of the current in the solenoid magnet under the neutralised condition and used these data to estimate the rms emittance of the beam. Simulations performed using equivalent Kapchinsky-Vladimirsky beam envelope equations with space charge neutralization factor are also presented to interpret the experimental results.

  20. Performance Studies of the Vibration Wire Monitor on the Test Stand with Low Energy Electron Beam

    NASA Astrophysics Data System (ADS)

    Okabe, Kota; Yoshimoto, Masahiro; Kinsho, Michikazu

    In the high intensity proton accelerator as the Japan Proton Accelerator Research Complex (J-PARC) accelerators, serious radiation and residual dose is induced by a small beam loss such a beam halo. Therefore, diagnostics of the beam halo formation is one of the most important issues to control the beam loss. For the beam halo monitor, the vibration wire monitor (VWM) has a potential for investigating the beam halo and weak beam scanning. The VWM has a wide dynamic range, high resolution and the VWM is not susceptible to secondary electrons and electric noises. We have studied the VWM features as a new beam-halo monitor on the test stand with low energy electron gun. The frequency shift of the irradiated vibration wire was confirmed about wire material and the electron beam profile measured by using the VWM was consistent with the results of the Faraday cup measurement. Also we calculated a temperature distribution on the vibration wire which is irradiated by the electron beam with the numerical simulation. The simulations have been fairly successful in reproducing the transient of the irradiated vibration wire frequency measured by test stand experiments. In this paper, we will report a result of performance evaluation for the VWM on the test stands and discuss the VWM for beam halo diagnostic

  1. Biomechanics of occlusion--implications for oral rehabilitation.

    PubMed

    Peck, C C

    2016-03-01

    The dental occlusion is an important aspect of clinical dentistry; there are diverse functional demands ranging from highly precise tooth contacts to large crushing forces. Further, there are dogmatic, passionate and often diverging views on the relationship between the dental occlusion and various diseases and disorders including temporomandibular disorders, non-carious cervical lesions and tooth movement. This study provides an overview of the biomechanics of the masticatory system in the context of the dental occlusion's role in function. It explores the adaptation and precision of dental occlusion, its role in bite force, jaw movement, masticatory performance and its influence on the oro-facial musculoskeletal system. Biomechanics helps us better understand the structure and function of biological systems and consequently an understanding of the forces on, and displacements of, the dental occlusion. Biomechanics provides insight into the relationships between the dentition, jaws, temporomandibular joints, and muscles. Direct measurements of tooth contacts and forces are difficult, and biomechanical models have been developed to better understand the relationship between the occlusion and function. Importantly, biomechanical research will provide knowledge to help correct clinical misperceptions and inform better patient care. The masticatory system demonstrates a remarkable ability to adapt to a changing biomechanical environment and changes to the dental occlusion or other components of the musculoskeletal system tend to be well tolerated.

  2. Performance studies of four-dimensional cone beam computed tomography

    NASA Astrophysics Data System (ADS)

    Qi, Zhihua; Chen, Guang-Hong

    2011-10-01

    Four-dimensional cone beam computed tomography (4DCBCT) has been proposed to characterize the breathing motion of tumors before radiotherapy treatment. However, when the acquired cone beam projection data are retrospectively gated into several respiratory phases, the available data to reconstruct each phase is under-sampled and thus causes streaking artifacts in the reconstructed images. To solve the under-sampling problem and improve image quality in 4DCBCT, various methods have been developed. This paper presents performance studies of three different 4DCBCT methods based on different reconstruction algorithms. The aims of this paper are to study (1) the relationship between the accuracy of the extracted motion trajectories and the data acquisition time of a 4DCBCT scan and (2) the relationship between the accuracy of the extracted motion trajectories and the number of phase bins used to sort projection data. These aims will be applied to three different 4DCBCT methods: conventional filtered backprojection reconstruction (FBP), FBP with McKinnon-Bates correction (MB) and prior image constrained compressed sensing (PICCS) reconstruction. A hybrid phantom consisting of realistic chest anatomy and a moving elliptical object with known 3D motion trajectories was constructed by superimposing the analytical projection data of the moving object to the simulated projection data from a chest CT volume dataset. CBCT scans with gantry rotation times from 1 to 4 min were simulated, and the generated projection data were sorted into 5, 10 and 20 phase bins before different methods were used to reconstruct 4D images. The motion trajectories of the moving object were extracted using a fast free-form deformable registration algorithm. The root mean square errors (RMSE) of the extracted motion trajectories were evaluated for all simulated cases to quantitatively study the performance. The results demonstrate (1) longer acquisition times result in more accurate motion delineation

  3. Nuclear Astrophysics and Structure Studies Using Low-energy RI Beams at CRIB

    SciTech Connect

    Yamaguchi, H.; Hashimoto, T.; Hayakawa, S.; Binh, D. N.; Kahl, D.; Kubono, S.

    2010-05-12

    CRIB (CNS Radioactive Ion Beam separator) is a low-energy RI beam separator at the Center for Nuclear Study (CNS) of the University of Tokyo. Using the RI beams at CRIB, Many measurements on proton and alpha resonance scatterings, (alpha,p) reactions, and others were peformed in recent years, mainly for studying astrophysical reactions and exotic nuclear structure. Among them, the results on the {sup 7}Be+p and {sup 7}Li+alpha resonance scatterings are presented.

  4. Biomechanical Assessment of Rucksack Shoulder Strap Attachment Location: Effect on Load Distribution to the Torso

    DTIC Science & Technology

    2001-05-01

    UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADPO 11003 TITLE: Biomechanical Assessment of Rucksack Shoulder Strap...ADP010987 thru ADPO11009 UNCLASSIFIED 20-1 Biomechanical Assessment of Rucksack Shoulder Strap Attachment Location: Effect on Load Distribution to the...Education Queen’s University Kingston, Ontario, Canada K7L 3N6 Summary The objective of this study was to conduct biomechanical testing of pack component

  5. Morphology and biomechanics of human heart

    NASA Astrophysics Data System (ADS)

    Chelnokova, Natalia O.; Golyadkina, Anastasiya A.; Kirillova, Irina V.; Polienko, Asel V.; Ivanov, Dmitry V.

    2016-03-01

    Object of study: A study of the biomechanical characteristics of the human heart ventricles was performed. 80 hearts were extracted during autopsy of 80 corpses of adults (40 women and 40 men) aged 31-70 years. The samples were investigated in compliance with the recommendations of the ethics committee. Methods: Tension and compression tests were performed with help of the uniaxial testing machine Instron 5944. Cardiometry was also performed. Results: In this work, techniques for human heart ventricle wall biomechanical properties estimation were developed. Regularities of age and gender variability in deformative and strength properties of the right and left ventricle walls were found. These properties were characterized by a smooth growth of myocardial tissue stiffness and resistivity at a relatively low strain against reduction in their strength and elasticity from 31-40 to 61-70 years. It was found that tissue of the left ventricle at 61-70 years had a lower stretchability and strength compared with tissues of the right ventricle and septum. These data expands understanding of the morphological organization of the heart ventricles, which is very important for the development of personalized medicine. Taking into account individual, age and gender differences of the heart ventricle tissue biomechanical characteristics allows to rationally choosing the type of patching materials during reconstructive operations on heart.

  6. Biomechanics of Esophageal Function in Eosinophilic Esophagitis

    PubMed Central

    Pandolfino, John E

    2012-01-01

    Eosinophilic Esophagitis (EoE) is a chronic inflammatory disease of the esophagus triggered by an immune response that leads to symptoms of dysphagia, chest pain, and food impaction. EoE is a clinicopathologic syndrome that requires clinical symptoms and pathologic findings for a diagnosis. The inflammatory process and eosinophilic infiltration of the esophagus in EoE lead to fibrosis and structural changes within the esophagus that cause esophageal dysfunction. The biomechanics of the esophageal function in EoE have been explored using manometry, impedance planimetry, barium esophagograms, and endoscopic ultrasound. These studies have identified several biomechanical changes to the esophagus in EoE including pan-esophageal pressurization on manometry, changes in esophageal compliance with decreased distentisbility by impedance planimetry, decreased esophageal luminal diameter by esophagograms, and dysfunction in the esophageal longitudinal muscles by endoscopic ultrasound. Treatments for the disease involve dietary changes, immunosuppressive drugs, and dilation techniques. However, the data regarding the effect of these therapies on altering mechanical properties of the esophagus is limited. As the pathogenesis of esophageal dysfunction in EoE appears multifactorial, further study of the biomechanics of EoE is critical to better diagnose, monitor and treat the disease. PMID:23105995

  7. Biomechanics of esophageal function in eosinophilic esophagitis.

    PubMed

    Read, Andrew J; Pandolfino, John E

    2012-10-01

    Eosinophilic Esophagitis (EoE) is a chronic inflammatory disease of the esophagus triggered by an immune response that leads to symptoms of dysphagia, chest pain, and food impaction. EoE is a clinicopathologic syndrome that requires clinical symptoms and pathologic findings for a diagnosis. The inflammatory process and eosinophilic infiltration of the esophagus in EoE lead to fibrosis and structural changes within the esophagus that cause esophageal dysfunction. The biomechanics of the esophageal function in EoE have been explored using manometry, impedance planimetry, barium esophagograms, and endoscopic ultrasound. These studies have identified several biomechanical changes to the esophagus in EoE including pan-esophageal pressurization on manometry, changes in esophageal compliance with decreased distentisbility by impedance planimetry, decreased esophageal luminal diameter by esophagograms, and dysfunction in the esophageal longitudinal muscles by endoscopic ultrasound. Treatments for the disease involve dietary changes, immunosuppressive drugs, and dilation techniques. However, the data regarding the effect of these therapies on altering mechanical properties of the esophagus is limited. As the pathogenesis of esophageal dysfunction in EoE appears multifactorial, further study of the biomechanics of EoE is critical to better diagnose, monitor and treat the disease.

  8. Interpreting principal components in biomechanics: representative extremes and single component reconstruction.

    PubMed

    Brandon, Scott C E; Graham, Ryan B; Almosnino, Sivan; Sadler, Erin M; Stevenson, Joan M; Deluzio, Kevin J

    2013-12-01

    Principal component analysis is a powerful tool in biomechanics for reducing complex multivariate datasets to a subset of important parameters. However, interpreting the biomechanical meaning of these parameters can be a subjective process. Biomechanical interpretations that are based on visual inspection of extreme 5th and 95th percentile waveforms may be confounded when extreme waveforms express more than one biomechanical feature. This study compares interpretation of principal components using representative extremes with a recently developed method, called single component reconstruction, which provides an uncontaminated visualization of each individual biomechanical feature. Example datasets from knee joint moments, lateral gastrocnemius EMG, and lumbar spine kinematics are used to demonstrate that the representative extremes method and single component reconstruction can yield equivalent interpretations of principal components. However, single component reconstruction interpretation cannot be contaminated by other components, which may enhance the use and understanding of principal component analysis within the biomechanics community.

  9. Rebuilding the Brookhaven high flux beam reactor: A feasibility study

    SciTech Connect

    Brynda, W.J.; Passell, L.; Rorer, D.C.

    1995-01-01

    After nearly thirty years of operation, Brookhaven`s High Flux Beam Reactor (HFBR) is still one of the world`s premier steady-state neutron sources. A major center for condensed matter studies, it currently supports fifteen separate beamlines conducting research in fields as diverse as crystallography, solid-state, nuclear and surface physics, polymer physics and structural biology and will very likely be able to do so for perhaps another decade. But beyond that point the HFBR will be running on borrowed time. Unless appropriate remedial action is taken, progressive radiation-induced embrittlement problems will eventually shut it down. Recognizing the HFBR`s value as a national scientific resource, members of the Laboratory`s scientific and reactor operations staffs began earlier this year to consider what could be done both to extend its useful life and to assure that it continues to provide state-of-the-art research facilities for the scientific community. This report summarizes the findings of that study. It addresses two basic issues: (i) identification and replacement of lifetime-limiting components and (ii) modifications and additions that could expand and enhance the reactor`s research capabilities.

  10. Cone beam CT tumor vasculature dynamic study (Murine model)

    NASA Astrophysics Data System (ADS)

    Yang, Dong; Ning, Ruola; Conover, David; Ricardo, Betancourt; Liu, Shaohua

    2008-03-01

    Tumor angiogenesis is the process by which new blood vessels are formed from the existing vessels in a tumor to promote tumor growth. Tumor angiogenesis has important implications in the diagnosis and treatment of various solid tumors. Flat panel detector based cone beam CT opens up a new way for detection of tumors, and tumor angiogenesis associated with functional CBCT has the potential to provide more information than traditional functional CT due to more overall coverage during the same scanning period and the reconstruction being isotropic resulting in a more accurate 3D volume intensity measurement. A functional study was conducted by using CBCT to determine the degree of the enhancement within the tumor after injecting the contrast agent intravenously. For typical doses of contrast material, the amount of enhancement is proportional to the concentration of this material within the region of interest. A series of images obtained at one location over time allows generation of time-attenuation data from which a number of semi-quantitative parameters, such as enhancement rate, can be determined. An in vivo mice study with and without mammo tumor was conducted on our prototype CBCT system, and half scan scheme is used to determine the time-intensity curve within the VOI of the mouse. The CBCT has an x-ray tube, a gantry with slip ring technology, and a 40×30 cm Varian Paxscan 4030CB real time FPD.

  11. Molecular-beam Studies of Primary Photochemical Processes

    DOE R&D Accomplishments Database

    Lee, Y. T.

    1982-12-01

    Application of the method of molecular-beam photofragmentation translational spectroscopy to the investigation of primary photochemical processes of polyatomic molecules is described. Examples will be given to illustrate how information concerning the energetics, dynamics, and mechanism of dissociation processes can be obtained from the precise measurements of angular and velocity distributions of products in an experiment in which a well-defined beam of molecules is crossed with a laser.

  12. Status of LHC crab activity simulations and beam studies

    SciTech Connect

    Calaga,R.; Assman, R.; Barranco, J.; Barranco, J.; Calaga, R.; Caspers, F.; Ciapala, E.; De-Maria, R.; Koutchouk, J. P.; Linnecar, T.; Metral, E.; Morita, A.; Solyak, N.; Sun, Y.; Tomas, R.; Tuckmantel, J.; Weiler, T.; Zimmermann, F.

    2009-05-04

    The LHC crab cavity program is advancing rapidly towards a first prototype which is anticipated to be tested during the early stages of the LHC phase I upgrade and commissioning. The general project status and some aspects related to crab optics, collimation, aperture constraints, impedances, noise effects. beam transparency and machine protection critical for a safe and robust operation of LHC beams with crab cavities are addressed here.

  13. On Monte Carlo modeling of megavoltage photon beams: A revisited study on the sensitivity of beam parameters

    SciTech Connect

    Chibani, Omar; Moftah, Belal; Ma, C.-M. Charlie

    2011-01-15

    Purpose: To commission Monte Carlo beam models for five Varian megavoltage photon beams (4, 6, 10, 15, and 18 MV). The goal is to closely match measured dose distributions in water for a wide range of field sizes (from 2x2 to 35x35 cm{sup 2}). The second objective is to reinvestigate the sensitivity of the calculated dose distributions to variations in the primary electron beam parameters. Methods: The GEPTS Monte Carlo code is used for photon beam simulations and dose calculations. The linear accelerator geometric models are based on (i) manufacturer specifications, (ii) corrections made by Chibani and Ma [''On the discrepancies between Monte Carlo dose calculations and measurements for the 18 MV Varian photon beam,'' Med. Phys. 34, 1206-1216 (2007)], and (iii) more recent drawings. Measurements were performed using pinpoint and Farmer ionization chambers, depending on the field size. Phase space calculations for small fields were performed with and without angle-based photon splitting. In addition to the three commonly used primary electron beam parameters (E{sub AV} is the mean energy, FWHM is the energy spectrum broadening, and R is the beam radius), the angular divergence ({theta}) of primary electrons is also considered. Results: The calculated and measured dose distributions agreed to within 1% local difference at any depth beyond 1 cm for different energies and for field sizes varying from 2x2 to 35x35 cm{sup 2}. In the penumbra regions, the distance to agreement is better than 0.5 mm, except for 15 MV (0.4-1 mm). The measured and calculated output factors agreed to within 1.2%. The 6, 10, and 18 MV beam models use {theta}=0 deg., while the 4 and 15 MV beam models require {theta}=0.5 deg. and 0.6 deg., respectively. The parameter sensitivity study shows that varying the beam parameters around the solution can lead to 5% differences with measurements for small (e.g., 2x2 cm{sup 2}) and large (e.g., 35x35 cm{sup 2}) fields, while a perfect agreement is

  14. Studies on Neutral Beam Injection into the SSPX Spheromak Plasma

    SciTech Connect

    Jayakumar, R; Pearlstein, L D; Casper, T A; Fowler, T K; Hill, D N; Hudson, B; McLean, H; Moller, J

    2007-10-19

    In the Sustained Spheromak Physics Experiment, (SSPX) ['Improved operation of the SSPX spheromak', R.D. Wood, D.N. Hill, E.B. Hooper, S. Woodruff1, H.S. McLean and B.W. Stallard, Nucl. Fusion 45 1582-1588 (2005)], plasmas with core electron temperatures reaching up to 500 eV at densities of 10{sup 20}/m{sup 3} have been sustained for several milliseconds, making them suitable as targets for neutral beam injection. High performance and further progress in understanding Spheromak plasma physics are expected if neutral beams are injected into the plasma. This paper presents the results of numerical 1.5 D modeling of the plasma to calculate neutral beam current drive and ion and electron heating. The results are presented for varying initial conditions of density, temperatures and profiles and beam energy, injection angle and power. Current drive efficiency (Ampere/Watt of absorbed power) of up to 0.08 can be achieved with best performance SSPX shots as target. Analyses of neutral beam heating indicate that ion temperatures of up to 1.5 keV and electron temperatures of up to 750 eV can be obtained with injection of about 1 MW of neutral beam for 5-10 ms and with diffusivities typically observed in SSPX. Injection targeting near the magnetic axis appears to be the best for heating and current drive. Effect of the current drive and evolution of SSPX equilibrium are discussed.

  15. Correlation study of a beam-position monitor and a photon-beam-position monitor in the PLS-II

    NASA Astrophysics Data System (ADS)

    Kim, Changbum; Shin, Seunghwan; Hwang, Ilmoon; Lee, Byung-Joon; Joo, Young-Do; Ha, Taekyun; Yoon, Jong Chel; Kim, Ghyung Hwa; Kim, Mungyung; Lee, Eun Hee; Kim, Ilyou; Huang, Jung-Yun

    2015-01-01

    The beam stability is one of the most important issues for the user service of the synchrotron radiation facility. After the upgrade of the Pohang Light Source (PLS-II), the electron-beam orbit is maintained within a root-mean-squred (rms) 1- μm range by using an orbit feedback system. However, that does not guarantee the radiation stability at the end of the beamline because unknown factors, such as focusing mirrors and double-crystal monocrometers, are present in the beamline. As a first step to solve this problem, photon-beam-position monitors (PBPMs) are installed in the front ends of the beamline to monitor the radiation stability. If the radiation is stable at the starting point of the beamline, we can move to the other components downstream that make the radiation unstable. In this paper, a correlation study will be presented between the beam-position monitor (BPM) and the PBPM. In addition, the effect of the orbit feedback system on the correlation will be described.

  16. Beam dynamics studies in the driver LINAC pre-Stripper section of the RIA facility.

    SciTech Connect

    Lessner, E. S.; Ostroumov, P. N.

    2003-07-10

    The RIA facility driver linac consists of about 400 superconducting (SC) independently phased rf cavities. The linac is designed to accelerate simultaneously several-charge-state beams to generate as much as 400 kW of uranium beam power. The linac beam dynamics is most sensitive to the focusing and accelerating-structure parameters of the prestripper section, where the uranium beam is accelerated from 0.17 keV/u to 9.4 MeV/u. This section is designed to accept and accelerate 2 charge states (28 and 29) of uranium beam from an ECR ion source. The prestripper section must be designed to minimize the beam emittance distortion of this two-charge-state beam. In particular, the inter-cryostat spaces must be minimized and beam parameters near transitions of the accelerating and focusing lattices must be matched carefully. Several sources of possible effective emittance growth are considered in the design of the prestripper section and a tolerance budget is established. Numerical beam dynamics studies include realistic electric and magnetic 3-dimensional field distributions in the SC rf cavities and SC solenoids. Error effects in the longitudinal beam parameters are studied.

  17. Beam loss studies in high-intensity heavy-ion linacs

    NASA Astrophysics Data System (ADS)

    Ostroumov, P. N.; Aseev, V. N.; Mustapha, B.

    2004-09-01

    The proposed Rare Isotope Accelerator (RIA) Facility, an innovative exotic-beam facility for the production of high-quality beams of short-lived isotopes, consists of a fully superconducting 1.4GV driver linac and a 140MV postaccelerator. To produce sufficient intensities of secondary beams the driver linac will provide 400kW primary beams of any ion from hydrogen to uranium. Because of the high intensity of the primary beams the beam losses must be minimized to avoid radioactivation of the accelerator equipment. To keep the power deposited by the particles lost on the accelerator structures below 1 W/m, the relative beam losses per unit length should be less than 10-5, especially along the high-energy section of the linac. A new beam dynamics simulation code TRACK has been developed and used for beam loss studies in the RIA driver linac. In the TRACK code, ions are tracked through the three-dimensional electromagnetic fields of every element of the linac starting from the electron cyclotron resonance (ECR) ion source to the production target. The simulation starts with a multicomponent dc ion beam extracted from the ECR. The space charge forces are included in the simulations. They are especially important in the front end of the driver linac. Beam losses are studied by tracking a large number of particles (up to 106) through the whole linac considering all sources of error such us element misalignments, rf field errors, and stripper thickness fluctuations. For each configuration of the linac, multiple sets of error values have been randomly generated and used in the calculations. The results are then combined to calculate important beam parameters, estimate beam losses, and characterize the corresponding linac configuration. To track a large number of particles for a comprehensive number of error sets (up to 500), the code TRACK was parallelized and run on the Jazz computer cluster at ANL.

  18. Effect of Graded Facetectomy on Lumbar Biomechanics

    PubMed Central

    Zeng, Zhi-li; Wu, Yang-chun; Zuo, Wei; Yu, Yan; Cheng, Li-ming

    2017-01-01

    Facetectomy is an important intervention for spinal stenosis but may lead to spinal instability. Biomechanical knowledge for facetectomy can be beneficial when deciding whether fusion is necessary. Therefore, the aim of this study was to investigate the biomechanical effect of different grades of facetectomy. A three-dimensional nonlinear finite element model of L3–L5 was constructed. The mobility of the model and the intradiscal pressure (IDP) of L4-L5 for standing were inside the data from the literature. The effect of graded facetectomy on intervertebral rotation, IDP, facet joint forces, and maximum von Mises equivalent stresses in the annuli was analyzed under flexion, extension, left/right lateral bending, and left/right axial rotation. Compared with the intact model, under extension, unilateral facetectomy increased the range of intervertebral rotation (IVR) by 11.7% and IDP by 10.7%, while the bilateral facetectomy increased IVR by 40.7% and IDP by 23.6%. Under axial rotation, the unilateral facetectomy and the bilateral facetectomy increased the IVR by 101.3% and 354.3%, respectively, when turned to the right and by 1.1% and 265.3%, respectively, when turned to the left. The results conclude that, after unilateral and bilateral facetectomy, care must be taken when placing the spine into extension and axial rotation posture from the biomechanical point of view.

  19. A biomechanical perspective on bone quality

    PubMed Central

    Hernandez, C.J.; Keaveny, T.M

    2007-01-01

    Observations that dual-energy x-ray absorptiometry (DXA) measures of areal bone mineral density cannot completely explain fracture incidence after anti-resorptive treatment have led to renewed interest in bone quality. Bone quality is a vague term, but generally refers to the effects of skeletal factors that contribute to bone strength but are not accounted for by measures of bone mass. Since a clinical fracture is ultimately a mechanical event, it follows then that any clinically relevant modification of bone quality must change bone biomechanical performance relative to bone mass. In this perspective, we discuss a framework for assessing the clinically relevant effects of bone quality based on two general concepts: 1) the biomechanical effects of bone quality can be quantified from analysis of the relationship between bone mechanical performance and bone density; and 2) because of its hierarchical nature, biomechanical testing of bone at different physical scales (<1mm, 1mm, 1 cm, etc.) can be used to isolate the scale at which the most clinically relevant changes in bone quality occur. As an example, we review data regarding the relationship between the strength and density in excised specimens of trabecular bone and highlight the fact that it is not yet clear how this relationship changes during aging, osteoporosis development, and anti-resorptive treatment. Further study of new and existing data using this framework should provide insight into the role of bone quality in osteoporotic fracture risk. PMID:16876493

  20. Design study of beam dynamics issues for 1 TeV next linear collider based upon the relativistic-klystron two-beam accelerator

    SciTech Connect

    Li, H.; Goffeney, N.; Henestroza, E.; Sessler, A.; Yu, S.; Houck, T.; Westenskow, G.

    1994-11-01

    A design study has recently been conducted for exploring the feasibility of a relativistic-klystron two-beam accelerator (RK-TBA) system as a rf power source for a 1 TeV linear collider. The author present, in this paper, the beam dynamics part of this study. They have achieved in their design study acceptable transverse and longitudinal beam stability properties for the resulting high efficiency and low cost RK-TBA.

  1. Biomechanical in vitro evaluation of three stable internal fixation techniques used in sagittal osteotomy of the mandibular ramus: a study in sheep mandibles

    PubMed Central

    de OLIVERA, Leandro Benetti; SANT'ANA, Eduardo; MANZATO, Antonio José; GUERRA, Fábio Luis Bunemer; ARNETT, G. William

    2012-01-01

    Among the osteotomies performed in orthognathic surgery, the sagittal osteotomy of the mandibular ramus (SOMR) is the most common, allowing a great range of movements and stable internal fixation (SIF), therefore eliminating the need of maxillomandibular block in the postoperative period. Objectives: The purpose of this study was to evaluate the biomechanical resistance of three national systems used for SIF in SOMR in sheep mandibles. Material and methods: The study was performed in 30 sheep hemi-mandibles randomly divided into 3 experimental groups, each containing 10 hemi-mandibles. The samples were measured to avoid discrepancies and then subjected to SOMR with 5-mm advancement. In group I, 2.0x12 mm screws were used for fixation, inserted in an inverted "L" pattern (inverted "L" group). In group II, fixation was performed with two 2.0x12 mm screws, positioned in a linear pattern and a 4-hole straight miniplate and four 2.0x6.0 mm monocortical screws (hybrid group). In group III, fixation was performed with two 4-hole straight miniplates and eight 2.0x6.0 mm monocortical screws (mini plate group). All materials used for SIF were supplied by Osteosin - SIN. The hemimandibles were subjected to vertical linear load test by Kratos K2000MP mechanical testing unit for loading registration and displacement. Results: All groups showed similar resistance during mechanical test for loading and displacement, with no statistically significant differences between groups according to analysis of variance. Conclusion: These results indicate that the three techniques of fixation are equally effective for clinical fixation of SOMR. PMID:23032203

  2. Study on shear strengthening of RC continuous T-beams using different layers of CFRP strips

    SciTech Connect

    Alferjani, M. B. S.; Samad, A. A. Abdul; Mohamad, Noridah; Elrawaff, Blkasem S.; Elzaroug, Omer

    2015-05-15

    Carbon fiber reinforced polymer (CFRP) laminates are externally bonded to reinforced concrete (RC) members to provide additional strength such as flexural, shear, etc. However, this paper presents the results of an experimental investigation for enhancing the shear capacity of reinforced concrete (RC) continuous T- beams using different layers of CFRP wrapping schemes. A total of three concrete beams were tested and various sheet configurations and layouts were studied to determine their effects on ultimate shear strength and shear capacity of the beams. One beam was kept as control beams, while other beams were strengthened with externally bonded CFRP strips with three side bonding and one or two layers of CFRP strips. From the test results, it was found that all schemes were found to be effective in enhancing the shear strength of RC beams. It was observed that the strength increases with the number of sheet layers provided the most effective strengthening for RC continuous T- beam. Beam strengthened using this scheme showed 23.21% increase in shear capacity as compared to the control beam. Two prediction models available in literature were used for computing the contribution of CFRP strips and compared with the experimental results.

  3. Study on shear strengthening of RC continuous T-beams using different layers of CFRP strips

    NASA Astrophysics Data System (ADS)

    Alferjani, M. B. S.; Samad, A. A. Abdul; Elrawaff, Blkasem S.; Elzaroug, Omer; Mohamad, Noridah

    2015-05-01

    Carbon fiber reinforced polymer (CFRP) laminates are externally bonded to reinforced concrete (RC) members to provide additional strength such as flexural, shear, etc. However, this paper presents the results of an experimental investigation for enhancing the shear capacity of reinforced concrete (RC) continuous T- beams using different layers of CFRP wrapping schemes. A total of three concrete beams were tested and various sheet configurations and layouts were studied to determine their effects on ultimate shear strength and shear capacity of the beams. One beam was kept as control beams, while other beams were strengthened with externally bonded CFRP strips with three side bonding and one or two layers of CFRP strips. From the test results, it was found that all schemes were found to be effective in enhancing the shear strength of RC beams. It was observed that the strength increases with the number of sheet layers provided the most effective strengthening for RC continuous T- beam. Beam strengthened using this scheme showed 23.21% increase in shear capacity as compared to the control beam. Two prediction models available in literature were used for computing the contribution of CFRP strips and compared with the experimental results.

  4. Harnessing biomechanics to develop cartilage regeneration strategies.

    PubMed

    Athanasiou, Kyriacos A; Responte, Donald J; Brown, Wendy E; Hu, Jerry C

    2015-02-01

    As this review was prepared specifically for the American Society of Mechanical Engineers H.R. Lissner Medal, it primarily discusses work toward cartilage regeneration performed in Dr. Kyriacos A. Athanasiou's laboratory over the past 25 years. The prevalence and severity of degeneration of articular cartilage, a tissue whose main function is largely biomechanical, have motivated the development of cartilage tissue engineering approaches informed by biomechanics. This article provides a review of important steps toward regeneration of articular cartilage with suitable biomechanical properties. As a first step, biomechanical and biochemical characterization studies at the tissue level were used to provide design criteria for engineering neotissues. Extending this work to the single cell and subcellular levels has helped to develop biochemical and mechanical stimuli for tissue engineering studies. This strong mechanobiological foundation guided studies on regenerating hyaline articular cartilage, the knee meniscus, and temporomandibular joint (TMJ) fibrocartilage. Initial tissue engineering efforts centered on developing biodegradable scaffolds for cartilage regeneration. After many years of studying scaffold-based cartilage engineering, scaffoldless approaches were developed to address deficiencies of scaffold-based systems, resulting in the self-assembling process. This process was further improved by employing exogenous stimuli, such as hydrostatic pressure, growth factors, and matrix-modifying and catabolic agents, both singly and in synergistic combination to enhance neocartilage functional properties. Due to the high cell needs for tissue engineering and the limited supply of native articular chondrocytes, costochondral cells are emerging as a suitable cell source. Looking forward, additional cell sources are investigated to render these technologies more translatable. For example, dermis isolated adult stem (DIAS) cells show potential as a source of

  5. The biomechanics of soccer: a review.

    PubMed

    Lees, A; Nolan, L

    1998-04-01

    This review considers the biomechanical factors that are relevant to success in the game of soccer. Three broad areas are covered: (1) the technical performance of soccer skills; (2) the equipment used in playing the game; and (3) the causative mechanisms of specific soccer injuries. Kicking is the most widely studied soccer skill. Although there are many types of kick, the variant most widely reported in the literature is the maximum velocity instep kick of a stationary ball. In contrast, several other skills, such as throwing-in and goalkeeping, have received little attention; some, for example passing and trapping the ball, tackling, falling behaviour, jumping, running, sprinting, starting, stopping and changing direction, have not been the subject of any detailed biomechanical investigation. The items of equipment reviewed are boots, the ball, artificial and natural turf surfaces and shin guards. Little of the research conducted by equipment manufacturers is in the public domain; this part of the review therefore concentrates on the mechanical responses of equipment, player-equipment interaction, and the effects of equipment on player performance and protection. Although the equipment has mechanical characteristics that can be reasonably well quantified, the player-equipment interaction is more difficult to establish; this makes its efficacy for performance or protection difficult to predict. Some soccer injuries may be attributable to the equipment used. The soccer boot has a poor protective capability, but careful design can have a minor influence on reducing the severity of ankle inversion injuries. Performance requirements limit the scope for reducing these injuries; alternative methods for providing ankle stability are necessary. Artificial surfaces result in injury profiles different from those on natural turf pitches. There is a tendency for fewer serious injuries, but more minor injuries, on artificial turf than on natural turf pitches. Players adapt to

  6. The biomechanics of seed germination.

    PubMed

    Steinbrecher, Tina; Leubner-Metzger, Gerhard

    2016-12-07

    From a biomechanical perspective, the completion of seed (and fruit) germination depends on the balance of two opposing forces: the growth potential of the embryonic axis (radicle-hypocotyl growth zone) and the restraint of the seed-covering layers (endosperm, testa, and pericarp). The diverse seed tissues are composite materials which differ in their dynamic properties based on their distinct cell wall composition and water uptake capacities. The biomechanics of embryo cell growth during seed germination depend on irreversible cell wall loosening followed by water uptake due to the decreasing turgor, and this leads to embryo elongation and eventually radicle emergence. Endosperm weakening as a prerequisite for radicle emergence is a widespread phenomenon among angiosperms. Research into the biochemistry and biomechanics of endosperm weakening has demonstrated that the reduction in puncture force of a seed's micropylar endosperm is environmentally and hormonally regulated and involves tissue-specific expression of cell wall remodelling proteins such as expansins, diverse hydrolases, and the production of directly acting apoplastic reactive oxygen. The endosperm-weakening biomechanics and its underlying cell wall biochemistry differ between the micropylar (ME) and chalazal (CE) endosperm domains. In the ME, they involve cell wall loosening, cell separation, and programmed cell death to provide decreased and localized ME tissue resistance, autolysis, and finally the formation of an ME hole required for radicle emergence. Future work will further unravel the molecular mechanisms, environmental regulation, and evolution of the diverse biomechanical cell wall changes underpinning the control of germination by endosperm weakening.

  7. Assessment of ankle and hindfoot stability and joint pressures using a human cadaveric model of a large lateral talar process excision: a biomechanical study.

    PubMed

    Sands, Andrew; White, Charles; Blankstein, Michael; Zderic, Ivan; Wahl, Dieter; Ernst, Manuela; Windolf, Markus; Hagen, Jennifer E; Richards, R Geoff; Stoffel, Karl; Gueorguiev, Boyko

    2015-03-01

    Lateral talar process fragment excision may be followed by hindfoot instability and altered biomechanics. There is controversy regarding the ideal fragment size for internal fixation versus excision and a concern that excision of a large fragment may lead to significant instability. The aim of this study was to assess the effect of a simulated large lateral talar process excision on ankle and subtalar joint stability.A custom-made seesaw rig was designed to apply inversion/eversion stress loading on 7 fresh-frozen human cadaveric lower legs and investigate them in pre-excision, 5 cm and 10 cm lateral talar process fragment excision states. Anteroposterior radiographs were taken to assess ankle and subtalar joint tilt and calculate angular change from neutral hindfoot alignment to 10-kg forced inversion/eversion. Ankle joint pressures and contact areas were measured under 30-kg axial load in neutral hindfoot alignment.In comparison to the pre-excision state, no significantly different mediolateral angular change was observed in the subtalar joint after 5 and 10 cm lateral talar process fragment excision in inversion and eversion. With respect to the ankle joint, 10-cm fragment excision produced significantly bigger inversion tibiotalar tilt compared with the pre-excision state, P = .04. No significant change of the ankle joint pressure and contact area was detected after 5 and 10-cm excision in comparison with the pre-excison state.An excision of up to 10 cm of the lateral talar process does not cause a significant instability at the level of the subtalar joint but might be a destabilizing factor at the ankle joint under inversion stress. The latter could be related to extensive soft tissue dissection required for resection.

  8. Acromioclavicular joint reconstruction using a tendon graft: a biomechanical study comparing a novel “sutured throughout” tendon graft to a standard tendon graft

    PubMed Central

    Naziri, Qais; Williams, Nadine; Hayes, Westley; Kapadia, Bhaveen H.; Chatterjee, Dipal; Urban, William P.

    2016-01-01

    Background: With a recurrence rate of over 30%, techniques that offer stronger acromioclavicular (AC) joint reconstruction through increased graft strength may provide longevity. The purpose of our study was to determine the biomechanical strength of a novel tendon graft sutured throughout compared to a native tendon graft in Grade 3 anatomical AC joint reconstruction. Methods: For this in vitro experiment, nine paired (n = 18) embalmed cadaveric AC joints of three males and six females (age 86 years, range 51–94 years) were harvested. Anatomic repair with fresh bovine Achilles tendon grafts without bone block was simulated. Specimens were divided into two groups; with group 1 using grafts with ultra-high molecular-weight polyethylene (UHMWPE) suture ran throughout the entire length. In group 2, reconstruction with only native allografts was performed. The distal scapula and humerus were casted in epoxy compound and mounted on the mechanical testing machine. Tensile tests were performed using a mechanical testing machine at the rate of 50 mm/min. Maximum load and displacement to failure were collected. Results: The average load to failure was significantly higher for group 1 compared to group 2, with mean values of 437.5 N ± 160.7 N and 94.4 N ± 43.6 N, (p = 0.001). The average displacement to failure was not significantly different, with 29.7 mm ± 10.6 mm in group 1 and 25 mm ± 9.1 mm in group 2 (p = 0.25). Conclusion: We conclude that a UHMWPE suture reinforced graft can provide a 3.6 times stronger AC joint reconstruction compared to a native graft. PMID:27163106

  9. Analysis of bending and buckling of pre-twisted beams: A bioinspired study

    NASA Astrophysics Data System (ADS)

    Zhao, Zi-Long; Zhao, Hong-Ping; Chang, Zheng; Feng, Xi-Qiao

    2014-08-01

    Twisting chirality is widely observed in artificial and natural materials and structures at different length scales. In this paper, we theoretically investigate the effect of twisting chiral morphology on the mechanical properties of elastic beams by using the Timoshenko beam model. Particular attention is paid to the transverse bending and axial buckling of a pre-twisted rectangular beam. The analytical solution is first derived for the deflection of a clamped-free beam under a uniformly or periodically distributed transverse force. The critical buckling condition of the beam subjected to its self-weight and an axial compressive force is further solved. The results show that the twisting morphology can significantly improve the resistance of beams to both transverse bending and axial buckling. This study helps understand some phenomena associated with twisting chirality in nature and provides inspirations for the design of novel devices and structures.

  10. Initial Experimental Studies of Electron Accumulation in a Heavy Ion Beam

    SciTech Connect

    Molvik, A W; Baca, D; Bieniosek, F M; Cohen, R H; Friedman, A; Furman, M A; Lee, E P; Lund, S M; Prost, L; Sakumi, A; Seidl, P A; Vay, J L

    2003-05-01

    Accelerators for heavy-ion inertial fusion energy (HIF) have an economic incentive to fit beam tubes tightly to beams, putting them at risk from electron clouds produced by emission of electrons and gas from walls. Theory and PIC simulations suggest that the electrons will be radially trapped in the {approx}>1 kV ion-beam potential. We are beginning studies on the High-Current Experiment (HCX) with unique capabilities to characterize electron production and trapping, the effects on ion beams, and mitigation techniques. We are measuring the flux of electrons and gas evolved from a target, whose angle to the beam can be varied between 78 and 88 degrees from normal incidence. Quadrupole magnets are operating with a variety of internal charged particle diagnostics to measure the beam halo loss, net charge, electron ionization rate, and gas density.

  11. Initial experimental studies of electron accumulation in a heavy-ion beam

    SciTech Connect

    Molvik, A.W.; Baca, D.; Bieniosek, F.M.; Cohen, R.H.; Friedman, A.; Furman, M.A.; Lee, E.P.; Lund, S.M.; Prost, L.; Sakumi, A.; Seidl, P.A.; Vay, J-L.

    2003-05-01

    Accelerators for heavy-ion inertial fusion energy (HIF) have an economic incentive to fit beam tubes tightly to beams, putting them at risk from electron clouds produced by emission of electrons and gas from walls. Theory and PIC simulations suggest that the electrons will be radially trapped in the {ge}1 kV ion-beam potential. We are beginning studies on the High-Current Experiment (HCX) with unique capabilities to characterize electron production and trapping, the effects on ion beams, and mitigation techniques. We are measuring the flux of electrons and gas evolved from a target, whose angle to the beam can be varied between 78{sup o} and 88{sup o} from normal incidence. Quadrupole magnets are operating with a variety of internal charged particle diagnostics to measure the beam halo loss, net charge, electron ionization rate, and gas density.

  12. Beam dynamics studies for transverse electromagnetic mode type rf deflectors

    DOE PAGES

    Ahmed, Shahid; Krafft, Geoffrey A.; Deitrick, Kirsten; ...

    2012-02-14

    We have performed three-dimensional simulations of beam dynamics for transverse electromagnetic mode (TEM) type rf deflectors: normal and superconducting. The compact size of these cavities as compared to the conventional TM110 type structures is more attractive particularly at low frequency. Highly concentrated electromagnetic fields between the parallel bars provide strong electrical stability to the beam for any mechanical disturbance. An array of six 2-cell normal conducting cavities or a single cell superconducting structure is enough to produce the required vertical displacement at the target point. Both the normal and superconducting structures show very small emittance dilution due to the verticalmore » kick of the beam.« less

  13. Beam Dynamics Studies of Parallel-Bar Deflecting Cavities

    SciTech Connect

    S. Ahmed, G. Krafft, K. Detrick, S. Silva, J. Delayen, M. Spata ,M. Tiefenback, A. Hofler ,K. Beard

    2011-03-01

    We have performed three-dimensional simulations of beam dynamics for parallel-bar transverse electromagnetic mode (TEM) type RF separators: normal- and super-conducting. The compact size of these cavities as compared to conventional TM$_{110}$ type structures is more attractive particularly at low frequency. Highly concentrated electromagnetic fields between the parallel bars provide strong electrical stability to the beam for any mechanical disturbance. An array of six 2-cell normal conducting cavities or a one- or two-cell superconducting structure are enough to produce the required vertical displacement at the Lambertson magnet. Both the normal and super-conducting structures show very small emittance dilution due to the vertical kick of the beam.

  14. Kinesiology/Biomechanics: Perspectives and Trends.

    ERIC Educational Resources Information Center

    Atwater, Anne E.

    1980-01-01

    Past and recent developments and future directions in kinesiology and biomechanics are reviewed. Similarities and differences between these two areas are clarified. The areas of kinesiology and biomechanics have distinct unique qualities and should be treated as separate disciplines. (CJ)

  15. Beam-Based Alignment, Tuning and Beam Dynamics Studies for the ATF2 Extraction Line and Final Focus System

    SciTech Connect

    White, Glen R.; Molloy, S.; Woodley, M.; /SLAC

    2008-07-25

    Using a new extraction line currently under construction, the ATF2 experiment plans to test the novel compact final focus optics design with local chromaticity correction intended for use in future linear colliders. With a 1.3 GeV design beam of 30nm normalized vertical emittance extracted from the ATF damping ring, the primary goal is to achieve a vertical spot-size at the IP waist of 37nm. We discuss our planned strategy for tuning the ATF2 beam to meet the primary goal. Simulation studies have been performed to asses the effectiveness of the strategy, including 'static' (installation) errors and dynamical effects (ground-motion, mechanical vibration, ring extraction jitter etc.). We have simulated all steps in the tuning procedure, from initial orbit establishment to final IP spot-size tuning. Through a Monte Carlo study of 100's of simulation seeds we find we can achieve a spot-size within {approx}10% of the design optics value in at least 75% of cases. We also ran a simulation to study the long-term performance with the use of beam-based feedbacks.

  16. Speciation through the lens of biomechanics: locomotion, prey capture and reproductive isolation.

    PubMed

    Higham, Timothy E; Rogers, Sean M; Langerhans, R Brian; Jamniczky, Heather A; Lauder, George V; Stewart, William J; Martin, Christopher H; Reznick, David N

    2016-09-14

    Speciation is a multifaceted process that involves numerous aspects of the biological sciences and occurs for multiple reasons. Ecology plays a major role, including both abiotic and biotic factors. Whether populations experience similar or divergent ecological environments, they often adapt to local conditions through divergence in biomechanical traits. We investigate the role of biomechanics in speciation using fish predator-prey interactions, a primary driver of fitness for both predators and prey. We highlight specific groups of fishes, or specific species, that have been particularly valuable for understanding these dynamic interactions and offer the best opportunities for future studies that link genetic architecture to biomechanics and reproductive isolation (RI). In addition to emphasizing the key biomechanical techniques that will be instrumental, we also propose that the movement towards linking biomechanics and speciation will include (i) establishing the genetic basis of biomechanical traits, (ii) testing whether similar and divergent selection lead to biomechanical divergence, and (iii) testing whether/how biomechanical traits affect RI. Future investigations that examine speciation through the lens of biomechanics will propel our understanding of this key process.

  17. Speciation through the lens of biomechanics: locomotion, prey capture and reproductive isolation

    PubMed Central

    Rogers, Sean M.; Langerhans, R. Brian; Jamniczky, Heather A.; Lauder, George V.; Stewart, William J.; Martin, Christopher H.; Reznick, David N.

    2016-01-01

    Speciation is a multifaceted process that involves numerous aspects of the biological sciences and occurs for multiple reasons. Ecology plays a major role, including both abiotic and biotic factors. Whether populations experience similar or divergent ecological environments, they often adapt to local conditions through divergence in biomechanical traits. We investigate the role of biomechanics in speciation using fish predator–prey interactions, a primary driver of fitness for both predators and prey. We highlight specific groups of fishes, or specific species, that have been particularly valuable for understanding these dynamic interactions and offer the best opportunities for future studies that link genetic architecture to biomechanics and reproductive isolation (RI). In addition to emphasizing the key biomechanical techniques that will be instrumental, we also propose that the movement towards linking biomechanics and speciation will include (i) establishing the genetic basis of biomechanical traits, (ii) testing whether similar and divergent selection lead to biomechanical divergence, and (iii) testing whether/how biomechanical traits affect RI. Future investigations that examine speciation through the lens of biomechanics will propel our understanding of this key process. PMID:27629033

  18. Simulation study of accelerator based quasi-mono-energetic epithermal neutron beams for BNCT.

    PubMed

    Adib, M; Habib, N; Bashter, I I; El-Mesiry, M S; Mansy, M S

    2016-01-01

    Filtered neutron techniques were applied to produce quasi-mono-energetic neutron beams in the energy range of 1.5-7.5 keV at the accelerator port using the generated neutron spectrum from a Li (p, n) Be reaction. A simulation study was performed to characterize the filter components and transmitted beam lines. The feature of the filtered beams is detailed in terms of optimal thickness of the primary and additive components. A computer code named "QMNB-AS" was developed to carry out the required calculations. The filtered neutron beams had high purity and intensity with low contamination from the accompanying thermal, fast neutrons and γ-rays.

  19. High transformer ratio drive beams for wakefield accelerator studies

    SciTech Connect

    England, R. J.; Ng, C.-K.; Frederico, J.; Hogan, M. J.; Litos, M.; Muggli, P.; Joshi, C.; An, W.; Andonian, G.; Mori, W.; Lu, W.

    2012-12-21

    For wakefield based acceleration schemes, use of an asymmetric (or linearly ramped) drive bunch current profile has been predicted to enhance the transformer ratio and generate large accelerating wakes. We discuss plans and initial results for producing such bunches using the 20 to 23 GeV electron beam at the FACET facility at SLAC National Accelerator Laboratory and sending them through plasmas and dielectric tubes to generate transformer ratios greater than 2 (the limit for symmetric bunches). The scheme proposed utilizes the final FACET chicane compressor and transverse collimation to shape the longitudinal phase space of the beam.

  20. Experimental Studies of Electron Beam Transport in Stellarator Focussing Fields

    DTIC Science & Technology

    1991-07-01

    3 Temporal width (ns) of beam pulse passed to Faraday cup ..... 37 1.0 INTRODUCTION The Spiral Line Induction Accelerator (SLIA)[ 1] is under...Faraday cup. The straight pipe is surrounded by a two-layer solenoid winding (zero net axial current). The solenoid coil provides a stand-off between...I ,4 / O~o Di/ (2 SD DI/ Z4/ 4. &e)DIA ’ 1 :)/ A Figure 3. Engineering, drawingy of the cross-section of the bend magnet, showing the beam pipe and A

  1. Biomechanics of soft tissues.

    PubMed

    Miller, K

    2000-01-01

    Recent developments in Computer-Integrated and Robot-Aided Surgery (in particular, the emergence of automatic surgical tools and robots (as well as advances in Virtual Reality techniques, call for closer examination of the mechanical properties of very soft tissues (such as brain, liver, kidney, etc.). Moreover, internal organs are very susceptible to trauma. In order to protect them properly against car crash and other impact consequences we need to be able to predict the organ deformation. Such prediction can be achieved by proper mathematical modelling followed by a computer simulation. The ultimate goal of our research into the biomechanics of these tissues is development of corresponding, realistic mathematical models. This paper contains experimental results of in vitro, uniaxial, unconfined compression of swine brain tissue obtained by the author in Mechanical Engineering Laboratory, Japan, and discusses liver and kidney in vivo compression experiments conducted in Highway Safety Research Institute and the Medical Centre of The University of Michigan. The stress-strain curves for investigated tissues are concave upward for all compression rates containing no linear portion from which a meaningful elastic modulus might be determined. The tissue response stiffened as the loading speed increased, indicating a strong stress (strain rate dependence. As the step in the direction towards realistic computer simulation of injuries and surgical procedures, this paper presents two mathematical representations of brain, liver and kidney tissue stiffness. Biphasic and single-phase models are discussed. The biphasic model is shown to be inappropriate due to its inability to account for strong stress-strain relationship. Agreement between the proposed single-phase models and experiment is good for compression levels reaching 30% and for loading velocities varying over five orders of magnitude. Presented mathematical models can find applications in computer and robot

  2. Biomechanics of Single Cortical Neurons

    PubMed Central

    Bernick, Kristin B.; Prevost, Thibault P.; Suresh, Subra; Socrate, Simona

    2011-01-01

    This study presents experimental results and computational analysis of the large strain dynamic behavior of single neurons in vitro with the objective of formulating a novel quantitative framework for the biomechanics of cortical neurons. Relying on the atomic force microscopy (AFM) technique, novel testing protocols are developed to enable the characterization of neural soma deformability over a range of indentation rates spanning three orders of magnitude – 10, 1, and 0.1 μm/s. Modified spherical AFM probes were utilized to compress the cell bodies of neonatal rat cortical neurons in load, unload, reload and relaxation conditions. The cell response showed marked hysteretic features, strong non-linearities, and substantial time/rate dependencies. The rheological data were complemented with geometrical measurements of cell body morphology, i.e. cross-diameter and height estimates. A constitutive model, validated by the present experiments, is proposed to quantify the mechanical behavior of cortical neurons. The model aimed to correlate empirical findings with measurable degrees of (hyper-) elastic resilience and viscosity at the cell level. The proposed formulation, predicated upon previous constitutive model developments undertaken at the cortical tissue level, was implemented into a three-dimensional finite element framework. The simulated cell response was calibrated to the experimental measurements under the selected test conditions, providing a novel single cell model that could form the basis for further refinements. PMID:20971217

  3. The Prosthetic Influence and Biomechanics on Peri-Implant Strain: a Systematic Literature Review of Finite Element Studies

    PubMed Central

    Puisys, Algirdas; Kuoppala, Ritva; Raustia, Aune; Juodzbalys, Gintaras

    2016-01-01

    ABSTRACT Objectives To systematically review risks of mechanical impact on peri-implant strain and prosthetic influence on stability across finite element studies. Material and Methods An online literature search was performed on MEDLINE and EMBASE databases published between 2011 and 2016. Following keywords tiered screening and selection of the title, abstract and full-text were performed. Studies of finite element analysis (FEA) were considered for inclusion that were written in English and revealed stress concentrations or strain at peri-implant bone level. Results There were included 20 FEA studies in total. Data were organized according to the following topics: bone layers, type of bone, osseointegration level, bone level, design of implant, diameter and length of implant, implant-abutment connection, type of supra-construction, loading axis, measurement units. The stress or strain at implant-bone contact was measured over all studies and numerical values estimated. Risks of overloading were accented as non-axial loading, misfits, cantilevers and the stability of peri-implant bone was related with the usage of platform switch connection of abutment. Conclusions Peri-implant area could be affected by non-axial loading, cantilever prosthetic elements, crown/implant ratio, type of implant-abutment connection, misfits, properties of restoration materials and antagonistic tooth. The heterogeneity of finite element analysis studies limits systematization of data. Results of these studies are comparable with other findings of in vitro, in vivo, prospective and retrospective studies. PMID:27833729

  4. Crossed molecular beam studies of atmospheric chemical reaction dynamics

    SciTech Connect

    Zhang, Jingsong

    1993-04-01

    The dynamics of several elementary chemical reactions that are important in atmospheric chemistry are investigated. The reactive scattering of ground state chlorine or bromine atoms with ozone molecules and ground state chlorine atoms with nitrogen dioxide molecules is studied using a crossed molecular beams apparatus with a rotatable mass spectrometer detector. The Cl + O3 → ClO + O2 reaction has been studied at four collision energies ranging from 6 kcal/mole to 32 kcal/mole. The derived product center-of-mass angular and translational energy distributions show that the reaction has a direct reaction mechanism and that there is a strong repulsion on the exit channel. The ClO product is sideways and forward scattered with respect to the Cl atom, and the translational energy release is large. The Cl atom is most likely to attack the terminal oxygen atom of the ozone molecule. The Br + O3 → ClO + O2 reaction has been studied at five collision energies ranging from 5 kcal/mole to 26 kcal/mole. The derived product center-of-mass angular and translational energy distributions are quite similar to those in the Cl + O3 reaction. The Br + O3 reaction has a direct reaction mechanism similar to that of the Cl + O3 reaction. The electronic structure of the ozone molecule seems to play the central role in determining the reaction mechanism in atomic radical reactions with the ozone molecule. The Cl + NO2 → ClO + NO reaction has been studied at three collision energies ranging from 10.6 kcal/mole to 22.4 kcal/mole. The center-of-mass angular distribution has some forward-backward symmetry, and the product translational energy release is quite large. The reaction proceeds through a short-lived complex whose lifetime is less than one rotational period. The experimental results seem to show that the Cl atom mainly attacks the oxygen atom instead of the nitrogen atom of the NO2

  5. [A biomechanical study of the mechanical stress transmission of dental implants using finite element analysis. Part II. Experiments].

    PubMed

    Szucs, Attila; Divinyi, Tamás; Bojtár, Imre; Polgár, Krisztina; Nasztanovics, Ferenc; Füstös, Attila; Lorincz, Adam; Barabás, József

    2006-10-01

    In the first part of this two-part study the possible uses of finite element analysis in studying the stress transmission of dental implants were reviewed. In the present second part our own experiments are presented. In the first series the effect of the geometric parameters and load types on mechanical stresses arising around cylindrical implants in bone were studied with 2D and 3D finite element analysis. In the second series the stress transmissions of various implant geometries were compared and an attempt was made to determine the optimal implant shape from the point of view of stress transmission.

  6. Design study of a superconducting gantry for carbon beam therapy

    NASA Astrophysics Data System (ADS)

    Kim, J.; Yoon, M.

    2016-09-01

    This paper describes beam-optics design of a gantry for carbon ions in cancer therapy accelerators. A compact design is important for such a gantry. The designed gantry is compact such that its size is comparable to the size of the existing proton gantries. This is made possible by introducing superconducting double helical coils for dipole magnets. The gantry optics is designed in such a way that it provides rotation-invariant optics, a variable beam size, and point-to-parallel scanning of a beam. For large-aperture magnet, a three-dimensional magnetic field distribution is obtained by invoking a computer code, and a number of particles are tracked by integrating equations of motion numerically together with a three-dimensional interpolation. The beam-shape distortion due to the fringe field is reduced to an acceptable level by optimizing the coil windings with the help of a genetic algorithm. Higher-order transfer coefficients are calculated and shown to be reduced greatly with appropriate optimization of the coil windings.

  7. The multilayer Fe/Hf studied with slow positron beam

    NASA Astrophysics Data System (ADS)

    Murashige, Y.; Tashiro, M.; Nakajyo, T.; Koizumi, T.; Kanazawa, I.; Komori, F.; Ito, Y.

    1997-04-01

    The positron annihilation parameter versus the incident positron energy is measured in the thin Fe films and the Fe/Hf bilayer on silica substrate, by means of the variable energetic slow-positron beam technique. We have analyzed the change in open-volume spaces and vacancy-type defects among the Fe microcrystals in these thin films with the deposition temperature.

  8. Experimental and numerical study of high intensity argon cluster beams

    SciTech Connect

    Korobeishchikov, N. G.; Kalyada, V. V.; Shmakov, A. A.; Zarvin, A. E.; Skovorodko, P. A.

    2014-12-09

    Experimental and numerical investigations of expansion of argon with homogeneous condensation in supersonic conical nozzle and in free jet behind it were carried out. Optimal parameters (stagnation pressure, nozzle-skimmer distance) for the formation of cluster beam with maximum intensity were determined. Two available models for nonequilibrium nucleation were tested. The numerical results are in satisfactory agreement with the measured data.

  9. Nanoscale characterization of the biomechanical hardening of bovine zona pellucida.

    PubMed

    Boccaccio, Antonio; Frassanito, Maria Cristina; Lamberti, Luciano; Brunelli, Roberto; Maulucci, Giuseppe; Monaci, Maurizio; Papi, Massimiliano; Pappalettere, Carmine; Parasassi, Tiziana; Sylla, Lakamy; Ursini, Fulvio; De Spirito, Marco

    2012-11-07

    The zona pellucida (ZP) is an extracellular membrane surrounding mammalian oocytes. The so-called zona hardening plays a key role in fertilization process, as it blocks polyspermy, which may also be caused by an increase in the mechanical stiffness of the ZP membrane. However, structural reorganization mechanisms leading to ZP's biomechanical hardening are not fully understood yet. Furthermore, a correct estimate of the elastic properties of the ZP is still lacking. Therefore, the aim of the present study was to investigate the biomechanical behaviour of ZP membranes extracted from mature and fertilized bovine oocytes to better understand the mechanisms involved in the structural reorganization of the ZP that may lead to the biomechanical hardening of the ZP. For that purpose, a hybrid procedure is developed by combining atomic force microscopy nanoindentation measurements, nonlinear finite element analysis and nonlinear optimization. The proposed approach allows us to determine the biomechanical properties of the ZP more realistically than the classical analysis based on Hertz's contact theory, as it accounts for the nonlinearity of finite indentation process, hyperelastic behaviour and material heterogeneity. Experimental results show the presence of significant biomechanical hardening induced by the fertilization process. By comparing various hyperelastic constitutive models, it is found that the Arruda-Boyce eight-chain model best describes the biomechanical response of the ZP. Fertilization leads to an increase in the degree of heterogeneity of membrane elastic properties. The Young modulus changes sharply within a superficial layer whose thickness is related to the characteristic distance between cross-links in the ZP filamentous network. These findings support the hypothesis that biomechanical hardening of bovine ZP is caused by an increase in the number of inter-filaments cross-links whose density should be higher in the ZP inner side.

  10. Experimental study of vortex ring interactions with a flexible beam; investigating the role of viscous effects

    NASA Astrophysics Data System (ADS)

    Pirnia, Alireza; Hu, Jiacheng; Peterson, Sean; Erath, Byron

    2016-11-01

    Energy can be extracted from flow instabilities in the environment for powering low consumption devices. When vortices pass tangentially over a flexible beam the lower pressure in the vortex core causes the beam to deflect, and induces sustained oscillations which can be converted into energy via piezoelectric materials. The beam dynamics can be parameterized according to the beam properties (nondimensional mass and stiffness ratios) as well as the vortex properties (size, vortex circulation strength and advection velocity). Recently, inviscid models have been developed to solve this fluid-structure interaction problem but they do not capture viscous interactions; features that become more prominent when the beam is positioned close to the vortex core. In this study the interaction of a vortex ring passing tangentially over a flexible beam as a function of circulation strength, beam properties, and offset distance are investigated to identify how viscous interactions influence the energy exchange process. Particle image velocimetry is acquired in tandem with the beam dynamics. The velocity and pressure fields, and transient beam dynamics are compared and contrasted with an inviscid model to identify the role of viscous interactions. This work was supported by the National Science Foundation Grant CBET #1511761.

  11. Beam studies at the SPEAR3 synchrotron using a digital optical mask

    SciTech Connect

    Zhang, H. D.; Fiorito, R. B.; Corbett, J.; Shkvarunets, A. G.; Tian, K.; Fisher, A.

    2016-05-01

    The 3GeV SPEAR3 synchrotron light source operates in top-up injection mode with up to 500 mA circulating in the storage ring (equivalently 392 nC). Each injection pulse contains 40–80 pC producing a contrast ratio between total stored charge and injected charge of about 6500:1. In order to study transient injected beam dynamics during user operations, it is desirable to optically image the injected pulse in the presence of the bright stored beam. In the present work this is done by imaging the visible component of the synchrotron radiation onto a digital micro-mirror-array device (DMD), which is then used as an optical mask to block out light from the bright central core of the stored beam. The physical masking, together with an asynchronously-gated, ICCD imaging camera, makes it possible to observe the weak injected beam component on a turn-by-turn basis. The DMD optical masking system works similar to a classical solar coronagraph but has some distinct practical advantages: i.e. rapid adaption to changes in the shape of the stored beam, a high extinction ratio for unwanted light and minimum scattering from the primary beam into the secondary optics. In this paper we describe the DMD masking method, features of the high dynamic range point spread function for the SPEAR3 optical beam line and measurements of the injected beam in the presence of the stored beam.

  12. Beam studies at the SPEAR3 synchrotron using a digital optical mask

    NASA Astrophysics Data System (ADS)

    Zhang, H. D.; Fiorito, R. B.; Corbett, J.; Shkvarunets, A. G.; Tian, K.; Fisher, A.

    2016-05-01

    The 3GeV SPEAR3 synchrotron light source operates in top-up injection mode with up to 500 mA circulating in the storage ring (equivalently 392 nC). Each injection pulse contains 40-80 pC producing a contrast ratio between total stored charge and injected charge of about 6500:1. In order to study transient injected beam dynamics during user operations, it is desirable to optically image the injected pulse in the presence of the bright stored beam. In the present work this is done by imaging the visible component of the synchrotron radiation onto a digital micro-mirror-array device (DMD), which is then used as an optical mask to block out light from the bright central core of the stored beam. The physical masking, together with an asynchronously-gated, ICCD imaging camera, makes it possible to observe the weak injected beam component on a turn-by-turn basis. The DMD optical masking system works similar to a classical solar coronagraph but has some distinct practical advantages: i.e. rapid adaption to changes in the shape of the stored beam, a high extinction ratio for unwanted light and minimum scattering from the primary beam into the secondary optics. In this paper we describe the DMD masking method, features of the high dynamic range point spread function for the SPEAR3 optical beam line and measurements of the injected beam in the presence of the stored beam.

  13. Nuclear Structure and Nuclear Astrophysics Studies with Fast Heavy-Ion Beams

    NASA Astrophysics Data System (ADS)

    Motobayashi, Tohru

    Collaboration between France and Japan on studies with fast RI (radioactive isotope) beams and related technical developments started in 1980s, when the GANIL accelerators and RIKEN cyclotron complex started operation and RI beam production technique was developed. Several examples of collaboration on nuclear physics and nuclear astrophysics experiments including related technical development are discussed.

  14. Crossed Molecular Beam Studies of the Reactions of Oxygen and Fluorine Atoms.

    DTIC Science & Technology

    1983-11-09

    Spectroscopy , Western Spectroscopy Association Conference, Asilomar, Pacific Grove, California, January 28-30, 1981. 96. Y. T. Lee, Dynamics of Infared ...reverse side If neceasary and Identify by block number) Molecular Beam Dynamics; Photofragmentation Translational Spectroscopy ; Unimolecular Decay...we initiated molecular beam photofragmentation translational spectroscopy experiments to study for the dissociation of ozone and other molecules

  15. Clinical biomechanics of the elbow.

    PubMed

    Lockard, Margary

    2006-01-01

    This paper describes the biomechanics of the articulations of the elbow joint that is relevant to therapists who design rehabilitation programs for patients following injuries or surgeries to the elbow. Individual and combined joint movements required for function such as activities of daily living are discussed, including normal arthrokinematics and the components that contribute to joint stability. The strain behavior of the nerves that cross the elbow is also reviewed. Therapists will understand the complexities of the biomechanics of the elbow that is necessary to design safe and effective rehabilitation programs.

  16. Biomechanics and functionality of hepatocytes in liver cirrhosis.

    PubMed

    Sun, Shan; Song, Zhenyuan; Cotler, Scott J; Cho, Michael

    2014-06-27

    Cirrhosis is a life-threatening condition that is generally attributed to overproduction of collagen fibers in the extracellular matrix that mechanically stiffens the liver. Chronic liver injury due to causes including viral hepatitis, inherited and metabolic liver diseases and external factors such as alcohol abuse can result in the development of cirrhosis. Progression of cirrhosis leads to hepatocellular dysfunction. While extensive studies to understand the complexity underlying liver fibrosis have led to potential application of anti-fibrotic drugs, no such FDA-approved drugs are currently available. Additional studies of hepatic fibrogenesis and cirrhosis primarily have focused on the extracellular matrix, while hepatocyte biomechanics has received limited attention. The role of hepatocyte biomechanics in liver cirrhosis remains elusive, and how the cell stiffness is correlated with biological functions of hepatocytes is also unknown. In this study, we demonstrate that the biomechanical properties of hepatocytes are correlated with their functions (e.g., glucose metabolism), and that hepatic dysfunction can be restored through modulation of the cellular biomechanics. Furthermore, our results indicate the hepatocyte functionality appears to be regulated through a crosstalk between the Rho and Akt signaling. These novel findings may lead to biomechanical intervention of hepatocytes and the development of innovative tissue engineering for clinical treatment to target liver cells rather than exclusively focusing on the extracellular matrix alone in liver cirrhosis.

  17. Single-scan scatter correction for cone-beam CT using a stationary beam blocker: a preliminary study

    NASA Astrophysics Data System (ADS)

    Niu, Tianye; Zhu, Lei

    2011-03-01

    The performance of cone-beam CT (CBCT) is greatly limited by scatter artifacts. The existing measurement-based methods have promising advantages as a standard scatter correction solution, except that they currently require multiple scans or moving the beam blocker during data acquisition to compensate for the missing primary data. These approaches are therefore unpractical in clinical applications. In this work, we propose a new measurement-based scatter correction method to achieve accurate reconstruction with one single scan and a stationary beam blocker, two seemingly incompatible features which enable simple and effective scatter correction without increase of scan time or patient dose. Based on CT reconstruction theory, we distribute the blocked areas over one projection where primary signals are considered to be redundant in a full scan. The CT image quality is not degraded even with primary loss. Scatter is accurately estimated by interpolation and scatter-corrected CT images are obtained using an FDK-based reconstruction. In a Monte Carlo simulation study, we first optimize the beam blocker geometry using projections on the Shepp-Logan phantom and then carry out a complete simulation of a CBCT scan on a water phantom. With the scatter-to-primary ratio around 1.0, our method reduces the CT number error from 293 to 2.9 Hounsfield unit (HU) around the phantom center. The proposed approach is further evaluated on a CBCT tabletop system. On the Catphan©600 phantom, the reconstruction error is reduced from 202 to 10 HU in the selected region of interest after the proposed correction.

  18. Biomechanical tactics of chiral growth in emergent aquatic macrophytes

    PubMed Central

    Zhao, Zi-Long; Zhao, Hong-Ping; Li, Bing-Wei; Nie, Ben-Dian; Feng, Xi-Qiao; Gao, Huajian

    2015-01-01

    Through natural selection, many plant organs have evolved optimal morphologies at different length scales. However, the biomechanical strategies for different plant species to optimize their organ structures remain unclear. Here, we investigate several species of aquatic macrophytes living in the same natural environment but adopting distinctly different twisting chiral morphologies. To reveal the principle of chiral growth in these plants, we performed systematic observations and measurements of morphologies, multiscale structures, and mechanical properties of their slender emergent stalks or leaves. Theoretical modeling of pre-twisted beams in bending and buckling indicates that the different growth tactics of the plants can be strongly correlated with their biomechanical functions. It is shown that the twisting chirality of aquatic macrophytes can significantly improve their survivability against failure under both internal and external loads. The theoretical predictions for different chiral configurations are in excellent agreement with experimental measurements. PMID:26219724

  19. Biomechanical tactics of chiral growth in emergent aquatic macrophytes

    NASA Astrophysics Data System (ADS)

    Zhao, Zi-Long; Zhao, Hong-Ping; Li, Bing-Wei; Nie, Ben-Dian; Feng, Xi-Qiao; Gao, Huajian

    2015-07-01

    Through natural selection, many plant organs have evolved optimal morphologies at different length scales. However, the biomechanical strategies for different plant species to optimize their organ structures remain unclear. Here, we investigate several species of aquatic macrophytes living in the same natural environment but adopting distinctly different twisting chiral morphologies. To reveal the principle of chiral growth in these plants, we performed systematic observations and measurements of morphologies, multiscale structures, and mechanical properties of their slender emergent stalks or leaves. Theoretical modeling of pre-twisted beams in bending and buckling indicates that the different growth tactics of the plants can be strongly correlated with their biomechanical functions. It is shown that the twisting chirality of aquatic macrophytes can significantly improve their survivability against failure under both internal and external loads. The theoretical predictions for different chiral configurations are in excellent agreement with experimental measurements.

  20. Preliminary Study of the Effects of Prolonged Acceleration on Spinal Dynamics of Baboons. 1. Acceleration. 2. Biomechanical Analysis

    DTIC Science & Technology

    1981-06-01

    cortical thickness, increased diameter/cortlcal thickness ratio, thinned and distorted epiphyseal plate, and thickened condylar cartilage in female rats...histomorphometric and histodynamic (tetracycline fixation) studies were conducted on calcified sections by analyzing six bone parameters (e,g,, bone volume , relative...growth cartilage alterations, a decrease in bone volume without an Increase in osteocytic activity, and (by tetracycline fluroescent analysis) a reduced

  1. [Biomechanical studies of forces occurring in the Ilizarov and Orthofix apparatuses during limb lengthening by distractive osteogenesis].

    PubMed

    Snela, S; Kisiel, J; Gregosiewicz, A; Dziubiński, F

    2000-01-01

    The magnitude of the distractive forces occurring in the Ilizarov and Orthofix apparatuses during limb lengthening by distractive osteogenesis has been investigated. Eighteen patients treated between 1995 and 1998 were included in the study. The data obtained were computerized and related to clinical, radiographic and sonographic findings. Typical and repeatable graphs of forces were found during the process of lengthening as well as typical relationships between the callus and the values of distractive forces.

  2. Can Radiocarpal-Spanning Fixation Be Made More Functional by Placing the Wrist in Extension? A Biomechanical Study Under Physiologic Loads

    PubMed Central

    Mann, Tobias; Lee, Daniel J.; Dahl, Jason

    2016-01-01

    We investigate whether applying an internal radiocarpal-spanning plate with the wrist in slight extension affects the biomechanical stability of the construct. An unstable distal radius fracture was simulated in 10 cadaveric specimens and immobilized with a radiocarpal-spanning plate holding the wrist in a neutral position. This construct was then physiologically loaded through the wrist flexor and extensor tendons. The resulting motion at the fracture was captured with a displacement sensor. The plate was then extended using an in situ bending technique, placing the wrist in extension, and the experiment was repeated. No statistically significant difference in the biomechanical stability afforded by the radiocarpal-spanning plate was detected with the wrist in extension compared to that in the traditional neutral position. The radiocarpal-spanning plate fixation was more stable when loaded through the extensor tendons. We conclude that immobilizing a distal radius fracture with an internal radiocarpal-spanning plate that holds the wrist in extension does not compromise biomechanical stability. PMID:26929853

  3. COMPUTATIONAL BEAM DYNAMICS STUDIES FOR IMPROVING THE RING INJECTION AND EXTRACTION SYSTEMS IN SNS

    SciTech Connect

    Holmes, Jeffrey A; Cousineau, Sarah M; Plum, Michael A; Wang, Jian-Guang

    2008-01-01

    The ring injection and extraction systems must function as designed in order for the Spallation Neutron Source (SNS) to achieve its specified performance. In commissioning and early operations we have encountered problems that have been traced to these systems. We experienced high beam losses in and around the injection dump, the rectification of which has necessitated ongoing study and development by a multidisciplinary team. Results already include a number of enhancements of existing features and the addition of new elements and diagnostics. The problem in the extraction region stems from tilted beam distributions observed in the ring-to-target beam transport line (RTBT) and on the target, thus complicating the control of the beam-on-target distribution. This indicates the inadvertent introduction of x-y beam coupling somewhere upstream of the RTBT. The present paper describes computational studies, using the ORBIT Code, addressed at the detailed understanding and solution of these problems.

  4. Generation of pulsed Bessel-Gauss beams using passive axicon-theoretical and experimental studies.

    PubMed

    Parsa, Shahrzad; Fallah, Hamid Reza; Ramezani, Mohsen; Soltanolkotabi, Mahmood

    2012-10-20

    We studied the conditions for generating passive Bessel-Gauss beams by using an axicon. We designed an appropriate Gaussian resonator and extracted a quasi-fundamental Gaussian mode from a pulsed Nd:YAG laser pumped by a Xenon flash lamp and measured its parameters, such as propagation factor, divergence angle, and Rayleigh range. Then we generated passive Bessel-Gauss beams using an axicon and investigated their propagation properties, theoretically and experimentally. For example, for the axicon of 1°, the output energy and the Rayleigh range of the generated Bessel-Gauss beams were measured to be 58 mJ and 229.3 mm, respectively. We compared these properties with our results of the Gaussian mode. Finally, by using axicons with different apex angles, and also by changing the beam spot size on the axicon, we generated Bessel-Gauss beams and studied their properties theoretically and experimentally.

  5. A biomechanical sorting of clinical risk factors affecting osteoporotic hip fracture.

    PubMed

    Luo, Y

    2016-02-01

    Osteoporotic fracture has been found associated with many clinical risk factors, and the associations have been explored dominantly by evidence-based and case-control approaches. The major challenges emerging from the studies are the large number of the risk factors, the difficulty in quantification, the incomplete list, and the interdependence of the risk factors. A biomechanical sorting of the risk factors may shed lights on resolving the above issues. Based on the definition of load-strength ratio (LSR), we first identified the four biomechanical variables determining fracture risk, i.e., the risk of fall, impact force, bone quality, and bone geometry. Then, we explored the links between the FRAX clinical risk factors and the biomechanical variables by looking for evidences in the literature. To accurately assess fracture risk, none of the four biomechanical variables can be ignored and their values must be subject-specific. A clinical risk factor contributes to osteoporotic fracture by affecting one or more of the biomechanical variables. A biomechanical variable represents the integral effect from all the clinical risk factors linked to the variable. The clinical risk factors in FRAX mostly stand for bone quality. The other three biomechanical variables are not adequately represented by the clinical risk factors. From the biomechanical viewpoint, most clinical risk factors are interdependent to each other as they affect the same biomechanical variable(s). As biomechanical variables must be expressed in numbers before their use in calculating LSR, the numerical value of a biomechanical variable can be used as a gauge of the linked clinical risk factors to measure their integral effect on fracture risk, which may be more efficient than to study each individual risk factor.

  6. In-vitro biomechanical study of a dorso-lumbo-sacral posterior supple instrumentation with variable section.

    PubMed

    Gayet, L E; Duport, G; Pries, P; Lavaste, F; Rideau, Y

    1996-10-01

    This study is designed to analyse the behavior, in the sagittal plane, of a complete human dorso-lumbar rachis, made rigid by the posterior instrumentation used for the treatment of scoliosis, on subjects suffering from DMD (Duchenne Muscular Dystrophy). The object of this analysis is to demonstrate the reliability of early surgery made possible by new instrumentation. Close review of the literature shows that the currently used Harrington or Luque instrumentations lead to mechanical complications, especially rod breaking, at the thoraco-lumbar junction. 8 specimens were non-destructively tested in-vitro. Compression and flexion were applied. For each test, rachis movements with and then without instrumentation, and also rod restraints were noted. The results show a linear stiffness multiplied by 8.3 in flexion and 11.6 in extension. The maximum restraint recorded for physiological displacements is 77 MPa. This remains largely under the fatigue-breaking limit of the metal used (stainless steel hammer-hardened 316 L, Young's modulus = 200,000 MPa, Poisson's ratio = 0.21, endurance limit = 350 MPa at 5 x 10(6) cycles). The results of this study encourage us to continue and develop early surgery in children affected by myopathy, with fixation of the complete rachis, including a lumbo-sacral arthrodesis and a supple dorsal part of the mounting, in the sagittal plane.

  7. Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

    PubMed Central

    Johansson, Pär; Jimbo, Ryo; Kjellin, Per; Currie, Fredrik; Chrcanovic, Bruno Ramos; Wennerberg, Ann

    2014-01-01

    Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bioinert and hydrophobic, and it does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano-modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n=24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n=24) were left uncoated (control). Half of the animals (n=12) were euthanized after 3 weeks of healing and the remaining (n=12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy, and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks (P=0.05) and 12 weeks (P=0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline hydroxyapatite coating to PEEK surfaces significantly increases its removal torque and biocompatibility. PMID:25152620

  8. Strength of the pin-bone interface of external fixation pins in the iliac crest. A biomechanical study.

    PubMed

    Liu, J; Lai, K A; Chou, Y L

    1995-01-01

    The iliac crest is a frequent insertion site for external fixation pins in treating unstable pelvic or acetabular fractures and in iliofemoral distraction for superiorly dislocated hips. The pin-bone interface is critical for the success of treatment, but studies of the iliac crest are lacking. The purpose of this study was to investigate the strength of the pin-bone interface of different pins and different insertion methods. Four types of commercial pins, Wagner pins, Orthofix cortical and cancellous screws, and AO pins, were driven into sheep iliac crests by 2 methods: the intercortical and the transcortical. Specimens were tested for pullout and bending with an Instron testing machine (Model 1343) at a extension rate of 0.02 mm/sec to failure. The results revealed that the intercortical method had a stronger pullout force than the transcortical in all types of screws (p < 0.05), probably caused by longer insertion in the bone. In the pullout tests, the Wagner pins were the strongest and the Orthofix cancellous screws were the weakest. There were no differences in bending. In the iliac crest, the intercortical method was the better way of driving pins, and the new Orthofix screws were not proven to be stronger than the Wagner pins, nor were the cancellous screws more suitable than the cortical ones.

  9. A Comparative Study on the Kinematic Biomechanical Effects of Tibia Vara in the Healthy and Diseased Individuals

    NASA Astrophysics Data System (ADS)

    Shahmohammadi, Mehrdad; Karami, Hossein; Bani, Milad Salimi; Zadeh, Hossein Bahreini; Karimi, Alireza; Navidbakhsh, Mahdi

    2016-08-01

    BACKGROUND: Malalignment about the knee leads to a pathological-mechanical load that may cause early osteoarthritis of the knee joint and high degree of deformity which may need surgical treatment. Analysis of the leg movements in the experimental cases and comparing acquired results to the normal ones during the gait is used as a practical method to evaluate the effects of the disease. METHOD: In this study, gait differences between the patients with tibia vara and normal people were studied according to the data obtained from a three-dimensional (3D) motion analyzer. Various parameters, including positions, linear and angular velocities, linear and angular accelerations, total velocity, total acceleration, and path length at different angels were extracted and processed via a 3D motion analyzer. Then the results of the patient and control groups were compared to identify the differences. RESULTS: The maximum and average values as well as sample entropy were also calculated for all the mentioned parameters. Among all, only nine remarkable differences between these two groups were observed. The results revealed that the great difference between the patients with tibia vara compared to the normal ones in gait cycle lies on the abnormal movement of fibula bone and less irregularities along the z-axis. CONCLUSIONS: These findings may have implications not only for understanding the differences between the tibia vara in the healthy and diseased individuals, but also for providing a practical understanding for the medical and orthopedic experts to propose a better treatment method.

  10. Effects of biosilicate and bioglass 45S5 on tibial bone consolidation on rats: a biomechanical and a histological study.

    PubMed

    Granito, Renata N; Ribeiro, Daniel Araki; Rennó, Ana Claudia M; Ravagnani, Christian; Bossini, Paulo S; Peitl-Filho, Oscar; Zanotto, Edgar D; Parizotto, Nivaldo A; Oishi, Jorge

    2009-12-01

    The purpose of this study was to investigate the effects of Bioglass 45S5 and Biosilicate, on bone defects inflicted on the tibia of rats. Fifty male Wistar rats were used in this study, and divided into five groups, including a control group, to test Biosilicate and Bioglass materials of two different particle sizes (180-212 microm or 300-355 microm). All animals were sacrificed 15 days after surgery. No significant differences (P > 0.05) were found when values for Maximal load, Energy Absorption and Structural Stiffness were compared among the groups. Histopathological evaluation revealed osteogenic activity in the bone defect for the control group. Nevertheless, it seems that the amount of fully formed bone was higher in specimens treated with Biosilicate (granulometry 300-355 microm) when compared to the control group. The same picture occurred regarding Biosilicate with granulometry 180-212 microm. Morphometric findings for bone area results (%) showed no statistically significant differences (P > 0.05) among the groups. Taken together, such findings suggest that, Biosilicate exerts more osteogenic activity when compared to Bioglass under subjective histopathological analysis.

  11. The biomechanical effects of the inclusion of a torque absorber on trans-femoral amputee gait, a pilot study.

    PubMed

    Van der Linden, M L; Twiste, N; Rithalia, S V S

    2002-04-01

    This paper reports on a pilot study investigating the effects on the gait of two transfemoral amputees of to the inclusion of a torque absorber (TA) and its location relative to the knee unit. Both subjects carried out gait tests with a prosthesis with no TA with, a TA proximal to the knee unit and with a TA distal to the knee unit. Three-dimensional gait analysis was carried out to establish the kinematic and kinetic gait parameters of both the prosthetic and sound side. It was found that the TA did not significantly affect the sagittal kinetic and kinematic parameters of the sound or the prosthetic side. However, for one subject the axial rotation of the socket relative to the foot was significantly greater with the TA. It was concluded that by using the methodology of this pilot study, it is possible to investigate the rotations in the transverse plane within the prosthetic limb and pelvis. Further, including a TA may reduce the relative motion between the stump and the socket and therefore may decrease skin breakdown due to diminished shear forces.

  12. Biomechanical analysis of distal radius fractures using intramedullary Kirschner wires.

    PubMed

    Tsai, Wen-Chi; Lin, Shang-Chih; Hsiao, Chun-Ching; Lu, Tung-Wu; Chao, Ching-Kong; Liu, Hwa-Chang

    2009-03-01

    Colles's fracture is the most common type of distal radius fracture. Surgically, it remains a challenge to restore radial height and volar tilt in order to regain optimal wrist function. Ulson's procedure provides a dynamic effect on fixing fractured fragments and restoring joint function using two wires. However, the biomechanical influences of bone and wire remain critical issues for fracture reduction and bone union in Ulson's procedure. Based on elastic beam and foundation theory, this study formulated a closed-form mathematical model to investigate the effects of bone and wire parameters on wire deflection and bony reaction. The wire deflection and bony reaction were chosen as the indices of wrist stability and reduction within the post-operative period. The predicted results showed that greater bone strength, higher wire stiffness, and longer wire contact length provide a more stable wire-bone construct, thus facilitating fracture reduction and bone union. The wire stiffness had a much more significant effect on the construct stability compared with bone quality and contact length. In terms of entry point and insertion angle, surgical planning for the contact length was more important than bony quality for stabilizing the whole wire-bone construct.

  13. Optical studies of ion-beam synthesized metal alloy nanoparticles

    NASA Astrophysics Data System (ADS)

    Magudapathy, P.; Srivatsava, S. K.; Gangopadhyay, P.; Amirthapandian, S.; Sairam, T. N.; Panigrahi, B. K.

    2015-06-01

    AuxAg1-x alloy nanoparticles with tunable surface plasmon resonance (SPR) have been synthesized on a silica glass substrate. A small Au foil on an Ag foil is irradiated as target substrates such that ion beam falls on both Ag foil and Au foils. Silica slides are kept at an angle ˜45° with respect to the metallic foils. While irradiating the metallic foils with 100 keV Ar+ ions, sputtered Au and Ag atoms get deposited on the silica-glass. In this configuration the foils have been irradiated by Ar+ ions to various fluences at room temperature and the sputtered species are collected on silica slides. Formation of AuxAg1-x nanoparticles has been confirmed from the optical absorption measurements. With respect to the exposure area of Au and Ag foils to the ion beam, the SPR peak position varies from 450 to 500 nm. Green photoluminescence has been observed from these alloy metal nanoparticles.

  14. Analytical and simulation studies for diode and triode ion beam extraction systems

    NASA Astrophysics Data System (ADS)

    M. Abdelrahman, M.; I. Basal, N.; G. Zakhary, S.

    2012-04-01

    This work is concerned with ion beam dynamics and compares the emittance to aberration ratios of two-and three-electrode extraction systems. The study is conducted with the aid of Version 7 of SIMION 3D ray-tracing software. The beam dependence on various parameters of the extraction systems is studied and the numerical results lead to qualitative conclusions. Ion beam characteristics using diode and triode extraction systems are investigated with the aid of the computer code SIMION 3 D, Version 7.0. The diode (two electrode extraction system) and triode (three-electrode extraction, acceleration-deceleration system) extraction systems are designed and optimized with different geometric parameters of the electrode system, voltage applied to the extraction electrode, and plasma parameters inside the ion source chamber, as well as by the ion beam space charge. This work attempts to describe the importance of the acceleration-deceleration extraction system. It shows that besides an increase of the beam energy, the ion beam has lower emittance than the two-electrode extraction system. Ion beams of the highest quality are extracted whenever the half-angular divergence is minimum for which the perveance current intensity and the extraction gap have optimum value. Knowing the electron temperature of the plasma is necessary to determine plasma potential and the exact beam energy.

  15. Diagnostic Assessment of Preparedness of Level One Sports Science Students for Biomechanics Modules

    ERIC Educational Resources Information Center

    Dixon, Sharon J.

    2005-01-01

    The primary objective of this study was to investigate the use of a diagnostic test to assess the preparedness of level one students for a sports biomechanics module. During their first week at university, a cohort of 108 students completed a diagnostic test at the end of their first lecture in sports biomechanics, with no prior notice. Upon…

  16. A comparative biomechanical analysis of term fetal membranes in human and domestic species

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The purpose of this study was to biomechanically characterize and compare human, porcine, equine, and ovine fetal membranes. Noncontact metrology was used for topographic analyses. Uniaxial tensile testing was performed to resolve specific biomechanical values. Puncture force and radial stresses we...

  17. Studies of Compound States of Negative Ions Using Laser Beams

    DTIC Science & Technology

    1985-08-15

    Beams" under Office of Naval Research (ONR) task NR 393-071. The reader will note a change in the title of the proposal from that of the previous year...final results, referring the reader to the papers in Appendix I for details. We will separate discussions of the progress into two parts. Part I will...were observed. Thus, neither model could explain the also included. The reader is referred to the articles by Sel- enhanced doubly differential cross

  18. Fundamental Study of Antimonide Nanostructures by Molecular Beam Epitaxy

    DTIC Science & Technology

    2016-02-04

    to conduct experimental work in molecular beam epitaxial growth of GaSb/GaAs and InSb/GaAs quantum dots (QDs) are conducted and compared with...Nanoelectronics, Quantum Nanostructures 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 10 19a.  NAME OF...September 2014 to July 2015 being conducted at Chulalongkorn University in Thailand. Following the research work on InAs quantum dots (QDs) and quantum

  19. Studies in High Current Beam Propagation at Reduced Pressures.

    DTIC Science & Technology

    1985-01-31

    43 3.2.2 Beam-Driven Chemistry in the Low-Density Regime..... 44 3.2.3 Non-Local, Non-Ohmic Conductivity Model ............. 45... chemistry processes (especially recombina- tion), and the role of radiative cooling in determining the onset of Spitzer conduction. Progress in...represent the cynamics of the two lower-energy groups, and a detailed air- chemistry reaction scheme also modifies the population of the low-energy group

  20. A biomechanical study of the flexor digitorum superficialis: effects of digital pulley excision and loss of the flexor digitorum profundus.

    PubMed

    Hamman, J; Ali, A; Phillips, C; Cunningham, B; Mass, D P

    1997-03-01

    Many reports have been devoted to characterizing the significance of the pulleys for the flexor digitorum profundus (FDP). However, no comparable work has been published on the flexor digitorum superficialis (FDS). This study characterized the FDS in a human cadaver model. Eleven fresh-frozen cadaver hands were used. By using a tensiometer, data were gathered for tendon excursion, tendon load, and work of flexion. Changes in efficiency were caused by excision of annular pulleys A1, A2, A3, and the palmar aponeurotic pulley. We also measured the effect of FDP excision on FDS efficiency. Sectioning of the A2 and A3 pulleys together caused statistically significant losses of efficiency in all three parameters (work, load, and excursion). When the FDP was removed from a finger with an intact pulley system, losses in both work and excursion efficiencies were significant. Removing the FDP while cutting different pulleys caused significant decrease in FDS excursion efficiency. We conclude that A2 and A3 are the most important pulleys for maintaining normal FDS function, and that the presence of the FDP in the digital sheath is essential for optimal FDS excursion efficiency.

  1. A multiscale model for the study of cardiac biomechanics in single-ventricle surgeries: a clinical case.

    PubMed

    Meoli, Alessio; Cutrì, Elena; Krishnamurthy, Adarsh; Dubini, Gabriele; Migliavacca, Francesco; Hsia, Tain-Yen; Pennati, Giancarlo; Taylor, Andrew; Giardini, Alessandro; Khambadkone, Sachin; Schievano, Silvia; de Leval, Marc; Hsia, T-Y; Bove, Edward; Dorfman, Adam; Baker, G Hamilton; Hlavacek, Anthony; Migliavacca, Francesco; Pennati, Giancarlo; Dubini, Gabriele; Marsden, Alison; Feinstein, Jeffrey; Vignon-Clementel, Irene; Figliola, Richard; McGregor, John

    2015-04-06

    Complex congenital heart disease characterized by the underdevelopment of one ventricular chamber (single ventricle (SV) circulation) is normally treated with a three-stage surgical repair. This study aims at developing a multiscale computational framework able to couple a patient-specific three-dimensional finite-element model of the SV to a patient-specific lumped parameter (LP) model of the whole circulation, in a closed-loop fashion. A sequential approach was carried out: (i) cardiocirculatory parameters were estimated by using a fully LP model; (ii) ventricular material parameters and unloaded geometry were identified by means of the stand-alone, three-dimensional model of the SV; and (iii) the three-dimensional model of SV was coupled to the LP model of the circulation, thus closing the loop and creating a multiscale model. Once the patient-specific multiscale model was set using pre-operative clinical data, the virtual surgery was performed, and the post-operative conditions were simulated. This approach allows the analysis of local information on ventricular function as well as global parameters of the cardiovascular system. This methodology is generally applicable to patients suffering from SV disease for surgical planning at different stages of treatment. As an example, a clinical case from stage 1 to stage 2 is considered here.

  2. Effect of recombinant human platelet-derived growth factor-BB-coated sutures on Achilles tendon healing in a rat model: A histological and biomechanical study

    PubMed Central

    Cummings, Stephen H; Grande, Daniel A; Hee, Christopher K; Kestler, Hans K; Roden, Colleen M; Shah, Neil V; Razzano, Pasquale; Dines, David M; Chahine, Nadeen O

    2012-01-01

    Purpose: Repairing tendon injuries with recombinant human platelet-derived growth factor-BB has potential for improving surgical outcomes. Augmentation of sutures, a critical component of surgical tendon repair, by coating with growth factors may provide a clinically useful therapeutic device for improving tendon repair. Therefore, the purpose of this study was to (a) coat Vicryl sutures with a defined dose of recombinant human platelet-derived growth factor-BB without additional coating excipients (e.g. gelatin), (b) quantify the recombinant human platelet-derived growth factor-BB released from the suture, and (c) use the recombinant human platelet-derived growth factor-BB-coated sutures to enhance tendon repair in a rat Achilles tendon transection model. Methods: Vicryl sutures were coated with 0, 0.3, 1.0, and 10.0 mg/mL concentrations of recombinant human platelet-derived growth factor-BB using a dip-coating process. In vitro release was quantified by an enzyme-linked immunosorbent assay. Acutely transected rat Achilles tendons were repaired using one of the four suture groups (n = 12 per group). Four weeks following repair, the tensile biomechanical and histological (i.e. collagen organization and angiogenesis) properties were determined. Results: A dose-dependent bolus release of recombinant human platelet-derived growth factor-BB occurred within the first hour in vitro, followed by a gradual release over 48 h. There was a significant increase in ultimate tensile strength (p < 0.01) in the two highest recombinant human platelet-derived growth factor-BB dose groups (1.9 ± 0.5 and 2.1 ± 0.5 MPa) relative to controls (1.0 ± 0.2 MPa). The modulus significantly increased (p = 0.031) with the highest recombinant human platelet-derived growth factor-BB dose group (7.2 ± 3.8 MPa) relative to all other groups (control: 3.5 ± 0.9 MPa). No significant differences were identified for the maximum load or stiffness. The histological collagen and angiogenesis scores

  3. Biomechanical and histologic basis of osseodensification drilling for endosteal implant placement in low density bone. An experimental study in sheep.

    PubMed

    Lahens, Bradley; Neiva, Rodrigo; Tovar, Nick; Alifarag, Adham M; Jimbo, Ryo; Bonfante, Estevam A; Bowers, Michelle M; Cuppini, Marla; Freitas, Helora; Witek, Lukasz; Coelho, Paulo G

    2016-10-01

    A bone drilling concept, namely osseodensification, has been introduced for the placement of endosteal implants to increase primary stability through densification of the osteotomy walls. This study investigated the effect of osseodensification on the initial stability and early osseointegration of conical and parallel walled endosteal implants in low density bone. Five male sheep were used. Three implants were inserted in the ilium, bilaterally, totaling 30 implants (n=15 conical, and n=15 parallel). Each animal received 3 implants of each type, inserted into bone sites prepared as follows: (i) regular-drilling (R: 2mm pilot, 3.2mm, and 3.8mm twist drills), (ii) clockwise osseodensification (CW), and (iii) counterclockwise (CCW) osseodensification drilling with Densah Bur (Versah, Jackson, MI, USA): 2.0mm pilot, 2.8mm, and 3.8mm multi-fluted burs. Insertion torque as a function of implant type and drilling technique, revealed higher values for osseodensification relative to R-drilling, regardless of implant macrogeometry. A significantly higher bone-to-implant contact (BIC) for both osseodensification techniques (p<0.05) was observed compared to R-drilling. There was no statistical difference in BIC as a function of implant type (p=0.58), nor in bone-area-fraction occupancy (BAFO) as a function of drilling technique (p=0.22), but there were higher levels of BAFO for parallel than conic implants (p=0.001). Six weeks after surgery, new bone formation along with remodeling sites was observed for all groups. Bone chips in proximity with the implants were seldom observed in the R-drilling group, but commonly observed in the CW, and more frequently under the CCW osseodensification technique. In low-density bone, endosteal implants present higher insertion torque levels when placed in osseodensification drilling sites, with no osseointegration impairment compared to standard subtractive drilling methods.

  4. An ergonomic study on the biomechanical consequences in children, generated by the use of computers at school.

    PubMed

    Paraizo, Claudia; de Moraes, Anamaria

    2012-01-01

    This research deals with the influence of the computer use in schools related to the children posture, in an ergonomic point of view. The research tries to identify probable causes for the children early postural constraints, relating it to the sedentary behavior and the lack of an ergonomic project in schools. The survey involved 186 children, between 8 and 12 years old, students of a private school in Rio de Janeiro-Brasil. An historical and theoretical school furniture research was conducted as well as a survey with the students and teachers, computer postural evaluation, ergonomic evaluation (RULA method), and observations in the computer classroom. The research dealt with the student's perception with respect to the furniture utilized by him in the classroom during the use of the computer, his body complaint, the time he spent working on the school computer and the possibility of the existence of sedentariness. Also deals with the teachers' perception and knowledge regarding ergonomics with reference to schoolroom furniture and its Regulatory Norms (RN). The purpose of the research work is to highlight the importance of this knowledge, having in view the possibility of the teachers' collaboration in the ergonomic adaptation of the classroom environment and in their conscientious opinion during the purchasing of this furniture. A questionnaire was utilized and its results showed some discontent on the part of the teachers with relation to the schoolroom furniture as well as the teachers' scant knowledge of Ergonomics.We conclude with a survey that despite the children had constraints in postural assessments and school furniture needs a major ergonomic action, the time that children use the computer at school is small compared with the time of use at home and therefore insufficient to be the main cause of quantified commitments, thus the study of computer use at home as a development and continuity of this research.

  5. Alpha-induced reaction studies using low-energy RI beams at CRIB

    SciTech Connect

    Yamaguchi, H.; Kahl, D.; Hu, J.; Kubono, S.; Hayakawa, S.; Hashimoto, T.

    2012-11-12

    CRIB (CNS Radioactive Ion Beam separator) is a low-energy RI beam separator at the Center for Nuclear Study (CNS) of the University of Tokyo. Studies on proton and alpha resonance scatterings, ({alpha}, p) reactions, and other types of measurements ({beta}-decay lifetimes etc.) have been performed using RI beams at CRIB, motivated by interests on astrophysical reactions and exotic nuclear structure. Among the studies at CRIB, the measurement of {sup 7}Li+{alpha}/{sup 7}Be+{alpha} resonant scatterings are presented.

  6. Studies on Nuclear Astrophysics and Exotic Structure at the Low-Energy RI Beam Facility CRIB

    NASA Astrophysics Data System (ADS)

    Yamaguchi, H.; Kahl, D.; Hayakawa, S.; Sakaguchi, Y.; Nakao, T.; Wakabayashi, Y.; Hashimoto, T.; Teranishi, T.; Kubono, S.; Cherubini, S.; Mazzocco, M.; Signorini, C.; Gulino, M.; Di Pietro, A.; Figuera, P.; La Cognata, M.; Lattuada, M.; Spitaleri, C.; Torresi, D.; Lee, P. S.; Lee, C. S.; Komatsubara, T.; Iwasa, N.; Okoda, Y.; Pierroutsakou, D.; Parascandolo, C.; La Commara, M.; Strano, E.; Boiano, C.; Boiano, A.; Manea, C.; Sánchez-Benítez, A. M.; Miyatake, H.; Watanabe, Y. X.; Ishiyama, H.; Jeong, S. C.; Imai, N.; Hirayama, Y.; Kimura, S.; Mukai, M.; Kim, Y. H.; Lin, C. J.; Jia, H. M.; Yan, L.; Yang, Y. Y.; Kawabata, T.; Kwon, Y. K.; Binh, D. N.; Khiem, L. H.; Duy, N. N.

    Studies on nuclear astrophysics, resonant structure, and nuclear reaction are going on at CRIB (CNS Radioactive Ion Beam separator), a low-energy RI beam separator operated by Center for Nuclear Study (CNS), the University of Tokyo. Two major methods used at CRIB to study nuclear reactions of astrophysical relevance are the resonant scattering, and direct measurements of (α,p) reactions using a thick-gas target. Several experiments for decay measurements and reaction mechanism are also performed using low-energy RI beams at CRIB. Some of the results from recent experiments at CRIB are discussed.

  7. A new methodology to measure the running biomechanics of amputees.

    PubMed

    Wilson, James Richard; Asfour, Shihab; Abdelrahman, Khaled Zakaria; Gailey, Robert

    2009-09-01

    We present a new methodology to measure the running biomechanics of amputees. This methodology combines the use of a spring-mass model and symmetry index, two standard techniques in biomechanics literature, but not yet used in concert to evaluate amputee biomechanics. The methodology was examined in the context of a pilot study to examine two transtibial amputee sprinters and showed biomechanically quantifiable changes for small adjustments in prosthetic prescription. Vertical ground reaction forces were measured in several trials for two transtibial amputees running at constant speed. A spring-mass model was used in conjunction with a symmetry index to observe the effect of varying prosthetic height and stiffness on running biomechanics. All spring-mass variables were significantly affected by changes in prosthetic prescription among the two subjects tested (p < 0.05). When prosthetic height was changed, both subjects showed significant differences, in Deltay(max), Deltal and contact time (t(c)) on the prosthetic limb and in k(vert) and k(leg) on the sound limb. The symmetry indices calculated for spring-mass variables were all significantly affected due to changes in prosthetic prescription for the male subject and all but the peak force (F(peak)) for the female subject. This methodology is a straight-forward tool for evaluating the effect of changes to prosthetic prescription.

  8. A selection of biomechanical research problems: From modeling to experimentation

    NASA Astrophysics Data System (ADS)

    Abbasi, Cyrus Omid

    The research undertakings within this manuscript illustrate the importance of biomechanics in today's science. Without doubt, biomechanics can be utilized to obtain a better understanding of many unsolved mysteries involved in the field of medicine. Moreover, biomechanics can be used to develop better prosthetic or surgical devices as well. Chapter 2 represents a medical problem, which has not been solved for more than a century. With the use of fundamental principles of biomechanics', a better insight of this problem and its possible causes were obtained. Chapter 3 investigates the mechanical interaction between the human teeth and some processed food products during mastication, which is a routine but crucial daily activity of a human being. Chapter 4 looks at a problem within the field of surgery. In this chapter the stability and reliability of two different Suturing-Techniques are explored. Chapters 5 and 6 represent new patent designs as a result of the investigations made in Chapter 4. Chapter 7 studies the impact and load transfer patterns during the collision between a child's head and the ground. All of the above mentioned chapters show the significance of biomechanics in solving a range of different medical problems that involve physical and or mechanical characters.

  9. Biomechanical Assessment in Models of Glaucomatous Optic Neuropathy

    PubMed Central

    Nguyen, Thao D.; Ethier, C. Ross

    2015-01-01

    The biomechanical environment within the eye is of interest in both the regulation of intraocular pressure and the loss of retinal ganglion cell axons in glaucomatous optic neuropathy. Unfortunately, this environment is complex and difficult to determine. Here we provide a brief introduction to basic concepts of mechanics (stress, strain, constitutive relationships) as applied to the eye, and then describe a variety of experimental and computational approaches used to study ocular biomechanics. These include finite element modeling, direct experimental measurements of tissue displacements using optical and other techniques, direct experimental measurement of tissue microstructure, and combinations thereof. Thanks to notable technical and conceptual advances in all of these areas, we are slowly gaining a better understanding of how tissue biomechanical properties in both the anterior and posterior segments may influence the development of, and risk for, glaucomatous optic neuropathy. Although many challenging research questions remain unanswered, the potential of this body of work is exciting; projects underway include the coupling of clinical imaging with biomechanical modeling to create new diagnostic tools, development of IOP control strategies based on improved understanding the mechanobiology of the outflow tract, and attempts to develop novel biomechanically-based therapeutic strategies for preservation of vision in glaucoma. PMID:26115620

  10. Clinical applications of biomechanics cinematography.

    PubMed

    Woodle, A S

    1986-10-01

    Biomechanics cinematography is the analysis of movement of living organisms through the use of cameras, image projection systems, electronic digitizers, and computers. This article is a comparison of cinematographic systems and details practical uses of the modality in research and education.

  11. Biomechanics and pathomechanisms of osteoarthritis.

    PubMed

    Egloff, Christian; Hügle, Thomas; Valderrabano, Victor

    2012-07-19

    Today, the most frequent chronic musculoskeletal disorder and the leading cause of disability in the elderly is osteoarthritis (OA). Approximately 43 million people in the United States and 15% of the world population are affected. Due to demographic changes, the incidence of OA is rapidly increasing, leading to an ascending socioeconomical and personal burden. Despite the exact cause of OA remains unknown, the pathogenic role of biomechanical dysfunction in OA is well established. For weight-bearing joints altered loading mechanisms, increased mechanical forces and changed biomechanics are significant contributing factors for initiation and progression of OA. Thus, OA is a disease of the whole joint, including muscles, tendons, ligaments, synovium and bone. This review focuses on the influence of biomechanics on the pathogenesis and progression of OA. We notably illustrate the pathological bioreactivity of soft tissues, subchondral bone and joint inflammation. Procedures, conservative or surgical, which actively alter the biomechanics of the lower limb, are promising strategies to treat symptoms as well as to influence disease progression in OA.

  12. Biomechanics of complex shoulder instability.

    PubMed

    Degen, Ryan M; Giles, Joshua W; Thompson, Stephen R; Litchfield, Robert B; Athwal, George S

    2013-10-01

    Identification and treatment of the osseous lesions associated with complex shoulder instability remains challenging. Further biomechanical testing is required to delineate critical defect values and determine which treatments provide improved glenohumeral joint stability for the various defect sizes, while minimizing the associated complications.

  13. Focused neutron beam dose deposition profiles in tissue equivalent materials: a pilot study for BNCT

    NASA Astrophysics Data System (ADS)

    Mayer, Rulon R.; Welsh, James; Chen-Mayer, Huaiyu H.

    1997-02-01

    Boron Neutron Capture Therapy (BNCT) has been limited by the inability to direct neutrons toward the therapeutic target and away from sensitive normal tissues. The recently developed Kumakhov lens has focused a broad incident low energy neutron beam in air to a sub-mm spot. This study examines the radiation does distribution of a converging beam passing through tissue equivalent materials. A neutron beam exiting a focusing lens is directed toward a stack of thin radiochromic media sandwiched between plastic sheets. The depth dose and beam profile within the tissue equivalent materials are determined by optical scanning and image processing of the individual radiochromic media sheets, a polymer based dosimetry medium which darkens upon exposure to ionizing radiation. The alpha particle emission from boron is examined by substituting a plastic sheet with a 6Li enriched lithium carbonate sheet positioned at the focal plane. The information will help determine the feasibility of applying the focused neutron beam to BNCT for therapy.

  14. Beam tracking strategies for studies of kinetic scales in the solar wind with THOR-CSW

    NASA Astrophysics Data System (ADS)

    De Keyser, Johan; Lavraud, Benoit; Neefs, Eddy; Berkenbosch, Sophie; Anciaux, Michel; Maggiolo, Romain

    2016-04-01

    Modern plasma spectrometers for monitoring the solar wind attempt to intelligently track the energy and direction of the solar wind beam in order to obtain solar wind velocity distributions more efficiently. Such beam tracking strategies offer some benefits, but also have their limitations and drawbacks. Benefits include an improved resolution and/or a faster velocity distribution function acquisition time. Limitations are due to instrument characteristics that tend to be optimized for a particular range of particle energies and arrival directions. A drawback is the risk to miss an important part of the velocity distribution or to lose track of the beam altogether. A comparison is presented of different beam tracking strategies under consideration for the THOR-CSW instrument in order to highlight a number of design decisions and their impact on the acquired velocity distributions. The gain offered by beam tracking in terms of increased time resolution turns out to be essential for studies of solar wind physics at kinetic scales.

  15. Transfer matrix of a Glaser magnet to study the dynamics of non-axisymmetric beam

    NASA Astrophysics Data System (ADS)

    Goswami, A.; Sing Babu, P.; Pandit, V. S.

    2012-06-01

    A Glaser magnet, having bell-shaped distribution of axial field, is often used to focus charged particle beams in the low energy section of accelerators and in many other devices. The transfer matrix of a Glaser magnet available in the literature is only for a rotationally axisymmetric beam. The objective of this paper is to obtain the 4D transfer matrix of a Glaser magnet for a non-axisymmetric beam having different emittances in the two transverse planes. Starting from the Hamiltonian of a single particle motion we have obtained the 4×4 linear transfer matrix of the Glaser magnet in symplectic form. The matrix so derived has been used to estimate the beam envelope through a Glaser magnet using the well known sigma matrix method. We have also studied the emittance growth that results from the coupling between the two transverse planes as the beam passes through the Glaser magnet.

  16. Dosimetric study of total skin irradiation with a scanning beam electron accelerator

    SciTech Connect

    Sharma, S.C.; Wilson, D.L.

    1987-05-01

    The Therac 20 6-MeV scanned electron beam may be used for partial or total skin therapy. The maximum field size at 1 m is 30 x 30 cm defined by a set of primary photon collimators in conjunction with secondary trimmers. We have studied electron beam profiles with and without trimmers at the nominal source--skin distance of 1 m versus extended distances of 3--5 m. We find that the trimmers limit the field size and add little to the beam uniformity at extended distances. Beam energy, dose distributions, and output factors at extended distances were measured for single and multiple field arrangements with and without trimmers. Beam parameters were measured after introducing a degrader that lowered the energy to 3.7 MeV.

  17. Dosimetric study of total skin irradiation with a scanning beam electron accelerator.

    PubMed

    Sharma, S C; Wilson, D L

    1987-01-01

    The Therac 20 6-MeV scanned electron beam may be used for partial or total skin therapy. The maximum field size at 1 m is 30 X 30 cm defined by a set of primary photon collimators in conjunction with secondary trimmers. We have studied electron beam profiles with and without trimmers at the nominal source-skin distance of 1 m versus extended distances of 3-5 m. We find that the trimmers limit the field size and add little to the beam uniformity at extended distances. Beam energy, dose distributions, and output factors at extended distances were measured for single and multiple field arrangements with and without trimmers. Beam parameters were measured after introducing a degrader that lowered the energy to 3.7 MeV.

  18. The biomechanical ambiguity of the articular surface.

    PubMed Central

    Kamalanathan, S; Broom, N D

    1993-01-01

    A series of micromechanical tests carried out on the articular surface of cartilage have provided an accurate description of the mechanical properties of any one site with respect to the orientation framework obtained from its characteristic split-line direction. Ultrastructural studies revealed little evidence that the split-line direction correlated strongly with any preferred alignment of fibrils. This paper therefore offers a new interpretation of the biomechanical significance of the widely used split-line test for the articular surface of cartilage. Images Fig. 9 Fig. 2 Fig. 6 Fig. 7 Fig. 8 Fig. 10 Fig. 11 PMID:8300433

  19. Studies of the beam extraction system of the GTS-LHC electron cyclotron resonance ion source at CERN

    SciTech Connect

    Toivanen, V. Küchler, D.

    2016-02-15

    The 14.5 GHz GTS-LHC Electron Cyclotron Resonance Ion Source (ECRIS) provides multiply charged heavy ion beams for the CERN experimental program. The GTS-LHC beam formation has been studied extensively with lead, argon, and xenon beams with varied beam extraction conditions using the ion optical code IBSimu. The simulation model predicts self-consistently the formation of triangular and hollow beam structures which are often associated with ECRIS ion beams, as well as beam loss patterns which match the observed beam induced markings in the extraction region. These studies provide a better understanding of the properties of the extracted beams and a way to diagnose the extraction system performance and limitations, which is otherwise challenging due to the lack of direct diagnostics in this region and the limited availability of the ion source for development work.

  20. Studies of the beam extraction system of the GTS-LHC electron cyclotron resonance ion source at CERN.

    PubMed

    Toivanen, V; Küchler, D

    2016-02-01

    The 14.5 GHz GTS-LHC Electron Cyclotron Resonance Ion Source (ECRIS) provides multiply charged heavy ion beams for the CERN experimental program. The GTS-LHC beam formation has been studied extensively with lead, argon, and xenon beams with varied beam extraction conditions using the ion optical code IBSimu. The simulation model predicts self-consistently the formation of triangular and hollow beam structures which are often associated with ECRIS ion beams, as well as beam loss patterns which match the observed beam induced markings in the extraction region. These studies provide a better understanding of the properties of the extracted beams and a way to diagnose the extraction system performance and limitations, which is otherwise challenging due to the lack of direct diagnostics in this region and the limited availability of the ion source for development work.

  1. Positron beam studies of saponite film prepared by precipitation method

    NASA Astrophysics Data System (ADS)

    Numata, K.; Sato, K.; Fujimoto, K.; Ito, K.

    2017-01-01

    Micrometer-sized saponite particles were isolated by means of gravitational sedimentation method applying Stokes’ law. The sample prepared with this method was film-like state with a thickness of ~ 30 μm and was semitransparent, indicating that the particles are homogeneously stacked all together. Positron lifetime spectroscopy using a slow positron beam yielded two components for ortho-positronium with lifetimes of 1.5 ns and 8.4 ns with the respective relative intensities of 13 % and 10 %. The results suggest that the self-assembly of the larger particles toward structural densification is suppressed for the present film in comparison with the smaller nanoparticles.

  2. 8B studied as a secondary beam at GANIL

    NASA Astrophysics Data System (ADS)

    Borcea, C.; Carstoiu, F.; Negoita, F.; Lewitowicz, M.; Saint-Laurent, M. G.; Anne, R.; Bazin, D.; Borrel, V.; Corre, J. M.; Dlouhy, Z.; Fomitchev, A.; Guillemaud-Mueller, D.; Keller, H.; Kordyasz, A.; Lukyanov, S.; Mueller, A. C.; Penionzhkevich, Yu.; Roussel-Chomaz, P.; Skobelev, N.; Sorlin, O.; Tarasov, O.

    1997-02-01

    The LISE spectrometer at GANIL has been used to form a 8B secondary beam. Using a multiple silicon telescope, data have been obtained for the reaction and break-up cross sections, as well as for the parallel momentum distribution of 7Be from break-up. For the first time, separate contributions to the break-up of diffraction and/or Coulomb dissociation and absorption mechanisms have been determined. The ensemble of data supports the existence in 8B of a "pigmy" halo.

  3. Ion beam analysis in cultural heritage studies: Milestones and perspectives

    SciTech Connect

    Dran, Jean-Claude; Calligaro, Thomas

    2013-07-18

    For three decades, ion beam analysis (IBA) in external mode was considered as the best choice for the characterisation of cultural heritage materials, as it combines excellent analytical performance and non-invasive character. However, in recent years, other analytical techniques arose as serious competitors, such as those based on synchrotron radiation (X-ray absorption, fluorescence or diffraction) or those using portable instruments (XRF, micro-Raman). It is shown that nevertheless IBA remains unmatched thanks to two unique features, namely the analysis of light elements and the high-resolution 3D chemical imaging.

  4. Noise Studies on Injected-Beam Crossed-Field Devices.

    DTIC Science & Technology

    1980-11-01

    In the gyrotron, where l magnetron injection guns are used, noise under crossed-field conditions is a limiting factor in the performance of the gun...charge I affected the behavior of the beam. Two factors which seemed to give rise to these effects appeared to be in the noise generated near the cathode...circuit I bars, or 0.270". The essential electrical properties of the meander circuit, the delay ratio (C/ vph ) and coupling impedance at the level of the

  5. Biomechanics of Wheat/Barley Straw and Corn Stover

    SciTech Connect

    Christopher T. Wright; Peter A. Pryfogle; Nathan A. Stevens; Eric D. Steffler; J. Richard Hess; Thomas H. Ulrich

    2005-03-01

    The lack of understanding of the mechanical characteristics of cellulosic feedstocks is a limiting factor in economically collecting and processing crop residues, primarily wheat and barley stems and corn stover. Several testing methods, including compression, tension, and bend have been investigated to increase our understanding of the biomechanical behavior of cellulosic feedstocks. Biomechanical data from these tests can provide required input to numerical models and help advance harvesting, handling, and processing techniques. In addition, integrating the models with the complete data set from this study can identify potential tools for manipulating the biomechanical properties of plant varieties in such a manner as to optimize their physical characteristics to produce higher value biomass and more energy efficient harvesting practices.

  6. Significant and meaningful effects in sports biomechanics research.

    PubMed

    Knudson, Duane

    2009-03-01

    Errors in statistical analysis of multiple dependent variables and in documenting the size of effects are common in the scientific and biomechanical literature. In this paper, I review these errors and several solutions that can improve the validity of sports biomechanics research reports. Studies examining multiple dependent variables should either control for the inflation of Type I errors (e.g. Holm's procedure) during multiple comparisons or use multivariate analysis of variance to focus on the structure and interaction of the dependent variables. When statistically significant differences are observed, research reports should provide confidence limits or effect sizes to document the size of the effects. Authors of sports biomechanics research reports are encouraged to analyse and present their data accounting for the experiment-wise Type I error rate, as well as reporting data documenting the size or practical significance of effects reaching their standard of statistical significance.

  7. [Air transport biomechanical risk: reduced mobility passengers' handling].

    PubMed

    Draicchio, F; Campoli, G; Silvetti, A; Badellino, E; Forzano, F; Ranavolo, A; Iavicoli, S; Campagna, G; Raffaele, G; Gismondi, M

    2012-01-01

    As the airport traffic increases there is a continuous increase of passengers with different motor disabilities. Disabled passenger's assistance causes a biomechanical overload in airport workers. Some disabled passengers are classified by IATA as WCHC (wheel chair in cabin or Charlie). Our study, was performed in one of the most important Italian airport on Charlie passengers (about 10% of all assistances). We identified four critical points: 1) wheelchair and baggage moving (unstable load), 2) inclined ramps with worker's backwards steps and braked wheelchair to prevent passenger tipping or falling, 3) transfer from standard wheelchair to bicycle wheelchair, specifically designed for the aisle; 4.) transfer from bicycle wheelchair to aircraft seat. The last two points required sometimes to lift passengers over the armrest and positioning them on a window side seat, causing a serious increase of biomechanical load. For each critical point we have proposed technical and organizational measures to reduce airport worker's biomechanical risk.

  8. Feasibility study of fusion plasma heating by relativistic high-current electron beams

    NASA Astrophysics Data System (ADS)

    Yakimenko, V.

    2017-03-01

    The goal of this research will be to study the feasibility of fusion plasma heating using ultra-short high intensity electron beam by dissipating the energy of excited wakes either in linear or nonlinear regimes.

  9. Biomechanics of fruits and vegetables.

    PubMed

    Peleg, K

    1985-01-01

    The scope of fruit and vegetable biomechanics is reviewed. Sources of mechanical injury to produce in harvesting, processing, storage, packaging and transportation are briefly described. A survey of produce handling and transportation environments was conducted, whereby an envelope model encompassing composite spectra of trucks, railroad, marine and cargo aircraft is presented. The protective quality, i.e. strength of shipping containers is quantified in static and dynamic loading such as encountered in storage, handling and transportation. Mechanical response of fruits and vegetables in quasistatic and dynamic loading are formulated by a nonlinear rheological model, whereby a time and deformation dependent relaxation modulus is defined. A realistic link is established between the model and real fruits and vegetables by test procedures for determination of the parameters in the governing nonlinear equations. Based on the nonlinear relaxation modulus, mechanical damage of fruits and vegetables is quantified for static compression, transients and vibration loading as well as for combined static and dynamic loading, by equations of contact circle diameter, bruise depth and contact pressure. Distribution of loads over a maximal number of contact points per fruit is linked to geometrical patterns of produce packs. The application of Shock Damage Boundary techniques for produce-package testing is described along with a case study comparing the protective qualities of two types of apple packs. Produce damage quantification by direct fruit inspection in terms of a 'Bruise Index' is described, including a practical example, comparing the protective qualities of three types of apple packs in shipping tests. Indirect methods of mechanical injury evaluation, based on weight loss and CO2 emission differences between bruised and wholesome fruits are also briefly discussed.

  10. Optical studies of ion-beam synthesized metal alloy nanoparticles

    SciTech Connect

    Magudapathy, P. Srivatsava, S. K.; Gangopadhyay, P.; Amirthapandian, S.; Sairam, T. N.; Panigrahi, B. K.

    2015-06-24

    Au{sub x}Ag{sub 1-x} alloy nanoparticles with tunable surface plasmon resonance (SPR) have been synthesized on a silica glass substrate. A small Au foil on an Ag foil is irradiated as target substrates such that ion beam falls on both Ag foil and Au foils. Silica slides are kept at an angle ∼45° with respect to the metallic foils. While irradiating the metallic foils with 100 keV Ar{sup +} ions, sputtered Au and Ag atoms get deposited on the silica-glass. In this configuration the foils have been irradiated by Ar{sup +} ions to various fluences at room temperature and the sputtered species are collected on silica slides. Formation of Au{sub x}Ag{sub 1-x} nanoparticles has been confirmed from the optical absorption measurements. With respect to the exposure area of Au and Ag foils to the ion beam, the SPR peak position varies from 450 to 500 nm. Green photoluminescence has been observed from these alloy metal nanoparticles.

  11. Expanded studies of linear collider final focus systems at the Final Focus Test Beam

    SciTech Connect

    Tenenbaum, Peter Gregory

    1995-12-01

    In order to meet their luminosity goals, linear colliders operating in the center-of-mass energy range from 3,50 to 1,500 GeV will need to deliver beams which are as small as a few Manometers tall, with x:y aspect ratios as large as 100. The Final Focus Test Beam (FFTB) is a prototype for the final focus demanded by these colliders: its purpose is to provide demagnification equivalent to those in the future linear collider, which corresponds to a focused spot size in the FFTB of 1.7 microns (horizontal) by 60 manometers (vertical). In order to achieve the desired spot sizes, the FFTB beam optics must be tuned to eliminate aberrations and other errors, and to ensure that the optics conform to the desired final conditions and the measured initial conditions of the beam. Using a combination of incoming-beam diagnostics. beam-based local diagnostics, and global tuning algorithms, the FFTB beam size has been reduced to a stable final size of 1.7 microns by 70 manometers. In addition, the chromatic properties of the FFTB have been studied using two techniques and found to be acceptable. Descriptions of the hardware and techniques used in these studies are presented, along with results and suggestions for future research.

  12. Corneal biomechanical properties in thyroid eye disease.

    PubMed

    Karabulut, Gamze Ozturk; Kaynak, Pelin; Altan, Cıgdem; Ozturker, Can; Aksoy, Ebru Funda; Demirok, Ahmet; Yılmaz, Omer Faruk

    2014-06-01

    The purpose of this study is to investigate the effect of thyroid eye disease (TED) on the measurement of corneal biomechanical properties and the relationship between these parameters and disease manifestations. A total of 54 eyes of 27 individuals with TED and 52 eyes of 30 healthy control participants were enrolled. Thyroid ophthalmopathy activity was defined using the VISA (vision, inflammation, strabismus, and appearance/exposure) classification for TED. The intraocular pressure (IOP) measurement with Goldmann applanation tonometer (GAT), axial length (AL), keratometry, and central corneal thickness (CCT) measurements were taken from each patient. Corneal biomechanical properties, including corneal hysteresis (CH) and corneal resistance factor (CRF) and noncontact IOP measurements, Goldmann-correlated IOP (IOPg) and corneal-compensated IOP (IOPcc) were measured with the Ocular Response Analyzer (ORA) using the standard technique. Parameters such as best corrected visual acuity, axial length, central corneal thickness, and corneal curvature were not statistically significant between the two groups (p > 0.05). IOP measured with GAT was higher in participants with TED (p < 0.001). The CH of TED patients was significantly lower than that of the control group. There was no significant difference in the corneal resistance factor between groups. However, IOPg and IOPcc were significantly higher in TED patients. CH and VISA grading of TED patients showed a negative correlation (p = 0.007). In conclusion, TED affects the corneal biomechanical properties by decreasing CH. IOP with GAT and IOPg is found to be increased in these patients. As the severity of TED increases, CH decreases in these patients.

  13. Biomechanics and biophysics of cancer cells ☆

    PubMed Central

    Suresh, Subra

    2010-01-01

    The past decade has seen substantial growth in research into how changes in the biomechanical and biophysical properties of cells and subcellular structures influence, and are influenced by, the onset and progression of human diseases. This paper presents an overview of the rapidly expanding, nascent field of research that deals with the biomechanics and biophysics of cancer cells. The review begins with some key observations on the biology of cancer cells and on the role of actin microfilaments, intermediate filaments and microtubule biopolymer cytoskeletal components in influencing cell mechanics, locomotion, differentiation and neoplastic transformation. In order to set the scene for mechanistic discussions of the connections among alterations to subcellular structures, attendant changes in cell deformability, cytoadherence, migration, invasion and tumor metastasis, a survey is presented of the various quantitative mechanical and physical assays to extract the elastic and viscoelastic deformability of cancer cells. Results available in the literature on cell mechanics for different types of cancer are then reviewed. Representative case studies are presented next to illustrate how chemically induced cytoskeletal changes, biomechanical responses and signals from the intracellular regions act in concert with the chemomechanical environment of the extracellular matrix and the molecular tumorigenic signaling pathways to effect malignant transformations. Results are presented to illustrate how changes to cytoskeletal architecture induced by cancer drugs and chemotherapy regimens can significantly influence cell mechanics and disease state. It is reasoned through experimental evidence that greater understanding of the mechanics of cancer cell deformability and its interactions with the extracellular physical, chemical and biological environments offers enormous potential for significant new developments in disease diagnostics, prophylactics, therapeutics and drug

  14. Biomechanical parameters of the BP-enriched bone cement.

    PubMed

    Matuszewski, Łukasz; Olchowik, Grażyna; Mazurkiewicz, Tomasz; Kowalczyk, Bartłomiej; Zdrojewska, Agata; Matuszewska, Anna; Ciszewski, Andrzej; Gospodarek, Małgorzata; Morawik, Iwona

    2014-05-01

    Bisphosphonates (BPs) are well-known substances with very efficient antiresorptive properties. Their beneficial actions are useful not only in achieving better bone mineral density but also in improving bone microarchitecture, strength and, consequently, its quality. Surgical cement, being a polymer composite, is required to be highly biocompatible and biotolerant. The goal of the presented study was to assess whether the enrichment of cement with pamidronate has changed its biomechanical properties. We compared the biomechanical parameters of clean bone cement and BP-enriched bone cement, which were both used formerly in our rat models. Biomechanical properties of BP-enriched bone cement are defined by two basic terms: stress and strain, which are caused by the influence of external force. In the investigatory process of the bone's biomechanical parameters, the compressive test and the three-point flexural tests were used. During the three-point flexural investigation, the sample was supported at both ends and loaded in the middle, resulting in a flexure. After a specific range of flexure, the sample was fractured. In obtained results, there were no significant differences in the values of the stress determined at the point of maximal load and the energy stored in the samples for proportional stress-strain limit (elastic region). There were also no significant differences in the density of the samples. The study shows that the enrichment of bisphosphonates causes yielding of the bone cement material. In the presented data, we conclude that use of pamidronate implanted in bone cement did not have a detrimental effect on its biomechanical properties. Therefore, the obtained results encouraged us to perform further in vivo experiments which assess the biomechanical properties of bones implanted with BP-enriched bone cement.

  15. VI.1. Gait analysis and synthesis: biomechanics, orthotics, prosthetics.

    PubMed

    Matjacić, Zlatko

    2010-01-01

    This contribution presents and establishes the biomechanical principles that underlie human walking. This is done by using a range of simplified biomechanical models of bipedal walking to explain the laws of movement and associated energetic requirements. Based on these simplified models, the measurements of normal walking are described. Selected pathological cases are used to illustrate the changes that occur in abnormal walking patterns. Finally, the basic design principles used when applying orthotics and prosthetics to enhance or restore impaired or missing function in walking are described for these case studies.

  16. Biomechanical Evaluation of Ascending Aortic Aneurysms

    PubMed Central

    Avanzini, Andrea; Battini, Davide

    2014-01-01

    The biomechanical properties of ascending aortic aneurysms were investigated only in the last decade in a limited number of studies. Indeed, in recent years, there has been a growing interest in this field in order to identify new predictive parameters of risk of dissection, which may have clinical relevance. The researches performed so far have been conducted according to the methods used in the study of abdominal aortic aneurysms. In most cases, uniaxial or biaxial tensile tests were used, while in a smaller number of studies other methods, such as opening angle, bulge inflation, and inflation-extension tests, were used. However, parameters and protocols of these tests are at present very heterogeneous in the studies reported in the literature, and, therefore, the results are not comparable and are sometimes conflicting. The purpose of this review then thence to provide a comprehensive analysis of the experimental methodology for determination of biomechanical properties in the specific field of aneurysms of the ascending aorta to allow for better comparison and understanding of the results. PMID:24991568

  17. Experimental Study on Nonlinear Vibrations of Fixed-Fixed Curved Beams

    NASA Astrophysics Data System (ADS)

    Kumar, Ajay; Patel, B. P.

    2016-07-01

    Nonlinear dynamic behavior of fixed-fixed shallow and deep curved beams is studied experimentally using non-contact type of electromagnetic shaker and acceleration measurements. The frequency response obtained from acceleration measurements is found to be in fairly good agreement with the computational response. The travellingwave phenomenon along with participation of higher harmonics and softening nonlinearity are observed. The experimental results on the internal resonance of curved beams due to direct excitation of anti-symmetric mode are reported for the first time. The deep curved beam depicts chaotic response at higher excitation amplitude.

  18. Figure of merit studies of beam power concepts for advanced space exploration

    NASA Technical Reports Server (NTRS)

    Miller, Gabriel; Kadiramangalam, Murali N.

    1990-01-01

    Surface to surface, millimeter wavelength beam power systems for power transmission on the lunar base were investigated. Qualitative/quantitative analyses and technology assessment of 35, 110 and 140 GHz beam power systems were conducted. System characteristics including mass, stowage volume, cost and efficiency as a function of range and power level were calculated. A simple figure of merit analysis indicates that the 35 GHz system would be the preferred choice for lunar base applications, followed closely by the 110 GHz system. System parameters of a 35 GHz beam power system appropriate for power transmission on a recent lunar base concept studied by NASA-Johnson and the necessary deployment sequence are suggested.

  19. Scintillating screens sensitivity and resolution studies for low energy, low intensity beam diagnostics

    SciTech Connect

    Harasimowicz, Janusz; Welsch, Carsten P.; Cosentino, Luigi; Finocchiaro, Paolo; Pappalardo, Alfio

    2010-10-15

    In order to investigate the limits of scintillating screens for beam profile monitoring in the ultra-low energy, ultra-low intensity regime, CsI:Tl, YAG:Ce, and a Tb glass-based scintillating fiber optic plate (SFOP) were tested. The screens response to 200 and 50 keV proton beams with intensities ranging from a few picoampere down to the subfemtoampere region was examined. In the following paper, the sensitivity and resolution studies are presented in detail for CsI:Tl and the SFOP, the two most sensitive screens. In addition, a possible use of scintillators for ultra-low energy antiproton beam monitoring is discussed.

  20. Effects of cord pretension and stiffness of the Dynesys system spacer on the biomechanics of spinal decompression- a finite element study

    PubMed Central

    2013-01-01

    Background The Dynesys system provides stability for destabilized spines while preserving segmental motion. However, clinical studies have demonstrated that the Dynesys system does not prevent adjacent segment disease. Moreover, biomechanical studies have revealed that the stiffness of the Dynesys system is comparable to rigid fixation. Our previous studies showed that adjusting the cord pretension of the Dynesys system alleviates stress on the adjacent level during flexion. We also demonstrated that altering the stiffness of Dynesys system spacers can alleviate stress on the adjacent level during extension of the intact spine. In the present study, we hypothesized that omitting the cord preload and changing the stiffness of the Dynesys system spacers would abate stress shielding on adjacent spinal segments. Methods Finite element models were developed for - intact spine (INT), facetectomy and laminectomy at L3-4 (DEC), intact spine with Dynesys system (IntDyWL), decompressed spine with Dynesys system (DecDyWL), decompressed spine with Dynesys system without cord preload (DecDyNL), and decompressed spine with Dynesys system assembled using spacers that were 0.8 times the standard diameter without cord pretension (DecDyNL0.8). These models were subjected to hybrid control for flexion, extension, axial rotation; and lateral bending. Results The greatest decreases in range of motion (ROM) at the L3-4 level occurred for axial rotation and lateral bending in the IntDyWL model and for flexion and extension in the DecDyWL model. The greatest decreases in disc stress occurred for extension and lateral bending in the IntDyWL model and for flexion in the DecDyWL model. The greatest decreases in facet contact force occurred for extension and lateral bending in the DecDyNL model and for axial rotation in the DecDyWL model. The greatest increases in ROMs at L2-3 level occurred for flexion, axial rotation and lateral bending in IntDyWL model and for extension in the Dec

  1. A 2D simulation study of Langmuir, whistler, and cyclotron maser instabilities induced by an electron ring-beam distribution

    SciTech Connect

    Lee, K. H.; Lee, L. C.; Omura, Y.

    2011-09-15

    We carried out a series of 2D simulations to study the beam instability and cyclotron maser instability (CMI) with the initial condition that a population of tenuous energetic electrons with a ring-beam distribution is present in a magnetized background plasma. In this paper, weakly relativistic cases are discussed with the ring-beam kinetic energy ranging from 25 to 100 keV. The beam component leads to the two-stream or beam instability at an earlier stage, and the beam mode is coupled with Langmuir or whistler mode, leading to excitation of beam-Langmuir or beam-whistler waves. When the beam velocity is large with a strong beam instability, the initial ring-beam distribution is diffused in the parallel direction rapidly. The diffused distribution may still support CMI to amplify the X1 mode (the fundamental X mode). On the contrary, when the beam velocity is small and the beam instability is weak, CMI can amplify the Z1 (the fundamental Z mode) effectively while the O1 (the fundamental O mode) and X2 (the second harmonic X mode) modes are very weak and the X1 mode is not excited. In this report, different cases with various parameters are presented and discussed for a comprehensive understanding of ring-beam instabilities.

  2. Three-dimensional numerical studies of the temperature anisotropy instability in intense charged particle beams

    NASA Astrophysics Data System (ADS)

    Startsev, Edward A.; Davidson, Ronald C.; Qin, Hong

    2005-05-01

    In neutral plasmas with a uniform magnetic field and strongly anisotropic distribution function (T∥/T⊥≪1) an electrostatic Harris-type collective instability may develop if the plasma is sufficiently dense. Such anisotropies develop naturally in accelerators, and a similar instability may lead to a deterioration of the beam quality in a one-component nonneutral charged particle beam. The instability may also lead to an increase in the longitudinal velocity spread, which would make the focusing of the beam difficult and impose a limit on the minimum spot size achievable in heavy ion fusion experiments. This paper reports the results of recent numerical studies of the temperature anisotropy instability using the newly developed Beam Eigenmodes And Spectra (bEASt) code for space-charge-dominated, low-emittance beams with large tune depression (ν/ν0≪1). Such high-intensity beams are relevant to next-step experiments such as the Integrated Beam Experiment (IBX), which would serve as proof-of-principal experiment for heavy-ion fusion.

  3. Transport studies of LPA electron beam towards the FEL amplification at COXINEL

    NASA Astrophysics Data System (ADS)

    Khojoyan, M.; Briquez, F.; Labat, M.; Loulergue, A.; Marcouillé, O.; Marteau, F.; Sharma, G.; Couprie, M. E.

    2016-09-01

    Laser Plasma Acceleration (LPA) [1] is an emerging concept enabling to generate electron beams with high energy, high peak current and small transverse emittance within a very short distance. The use of LPA can be applied to the Free Electron Laser (FEL) [2] case in order to investigate whether it is suitable for the light amplification in the undulator. However, capturing and guiding of such beams to the undulator is very challenging, because of the large divergence and high energy spread of the electron beams at the plasma exit, leading to large chromatic emittances. A specific beam manipulation scheme was recently proposed for the COXINEL (Coherent X-ray source inferred from electrons accelerated by laser) setup, which makes an advantage from the intrinsically large chromatic emittance of such beams [3]. The electron beam transport is studied using two simulation codes: a SOLEIL in-house one and ASTRA [4]. The influence of the collective effects on the electron beam performance is also examined.

  4. Ionosphere/microwave beam interaction study. [satellite solar energy conversion

    NASA Technical Reports Server (NTRS)

    Duncan, L. M.; Gordon, W. E.

    1977-01-01

    A solar power satellite microwave power density of 20mw sq cm was confirmed as the level where nonlinear interactions may occur in the ionosphere, particularly at 100 km altitude. Radio wave heating at this altitude, produced at the Arecibo Observatory, yielded negative results for radio wave heating of an underdense ionosphere. Overdense heating produced striations in the ionosphere which may cause severe radio frequency interference problems under certain conditions. The effects of thermal self-focusing are shown to be limited severely geographically. The aspect sensitivity of field-aligned striations makes interference-free regions above magnetic latitude about 60 deg. A test program is proposed to simulate the interaction of the SPS beam with the ionosphere, to measure the effects of the interaction on the ionosphere and on communication and navigation systems, and to interpret the results.

  5. Computational study of ion beam extraction phenomena through multiple apertures

    SciTech Connect

    Hu, Wanpeng; Sang, Chaofeng; Tang, Tengfei; Wang, Dezhen; Li, Ming; Jin, Dazhi; Tan, Xiaohua

    2014-03-15

    The process of ion extraction through multiple apertures is investigated using a two-dimensional particle-in-cell code. We consider apertures with a fixed diameter with a hydrogen plasma background, and the trajectories of electrons, H{sup +} and H{sub 2}{sup +} ions in the self-consistently calculated electric field are traced. The focus of this work is the fundamental physics of the ion extraction, and not particular to a specific device. The computed convergence and divergence of the extracted ion beam are analyzed. We find that the extracted ion flux reaching the extraction electrode is non-uniform, and the peak flux positions change according to operational parameters, and do not necessarily match the positions of the apertures in the y-direction. The profile of the ion flux reaching the electrode is mainly affected by the bias voltage and the distance between grid wall and extraction electrode.

  6. Electron beam radiation effects on UHMWPE: an EPR study.

    PubMed

    Brunella, Valentina; Paganini, Maria Cristina

    2011-09-01

    Electron paramagnetic resonance (EPR) technique has been employed to detect and characterise a series of different radical species generated in ultra-high molecular weight polyethylene (UHMWPE) via electron beam irradiation. Three different radical species have been found and assigned on the basis of their EPR spectra and of the related computer simulations. A secondary alkyl species, the prevalent one, is present immediately after irradiation, an allyl species appears only 24 h after irradiation when the alkyl species disappears.The third species, clearly visible at high microwave power only, has been observed for the first time and assigned to a tertiary alkyl carbon radical, whose formation is strictly connected with a Y-shape crosslink and a migration of the unpaired electron on a carbon atom localised in an adjacent position.

  7. Confinement studies during neutral beam injection in PLT

    SciTech Connect

    Goldston, R.; Davis, S.; Eubank, H.

    1980-12-01

    Neutral beam injection experiments on PLT have provided definitive information on ion energy confinement in highly collisionless plasmas. We find that ion thermal conduction is consistent, within a factor of approx. 3, with neoclassical theory, and that anomalous thermal convection of ion energy is a factor of 2-3 less than would be calculated from the INTOR D/sub e/ with a convection loss term of the form 5/2nkTv/sub r/. From our experiments with a shunted TF coil we have found that a single shallow ripple well of 2.5% has a neglible effect on ion energy confinement, even at the lowest collisionality obtainable on PLT. Scrutiny of the analytic theories of ripple induced transport motivated by these experiments, suggests that more theoretical (and perhaps numerical) work is needed in this area.

  8. The electron beam welding of dissimilar materials - case study

    NASA Astrophysics Data System (ADS)

    Munteanu, A.

    2016-11-01

    The modalities to realize the welding workpieces are multiple. The electron beam welding is one of them. One can weld two different types of materials that give the possibility to reduce the cost of workpiece, if the active part is realised of rich materials welded on components with inferior phisico-mecanical characteristics. The procedure provides great flexibility to the product designs through efficient use of each type of material. So this aspects lead to the necessity to join dissimilar metals. Different tables are given in the specific literature regarding the possible combination. Conflicts may arise by the compromises required for to the optimum heat control of the two dissimilar materials used. But nowadays, more and more frequently are meet the welding of dissimilar metals, thus, the objective of this article is to provide information regarding the particular case of welding between stainless steel and copper without the filler material use.

  9. A study of refraction of a cylindrical laser beam in stratified liquid

    NASA Astrophysics Data System (ADS)

    Rinkevichyus, B. S.; Sapronov, M. V.; Pavlov, I. N.

    2016-09-01

    Refraction of a cylindrical laser beam in a transition layer at the interface of two liquids with different optical characteristics is studied theoretically and experimentally. A theoretical basis for calculations of the beam trajectory in the transition layer of stratified liquid is given. Two- and three-dimensional images (2D and 3D refractograms) of a cylindrical laser beam inside and outside the media are obtained on the basis of a tangential model of the refractive index profile. The influence of the parameters of the laser beam and media on the appearance of refractograms is studied and the optimal experimental conditions are selected with the use of computer simulation. A scheme of the setup for recording digital 2D refractogram and experimental results are presented. Algorithms for digitizing experimental images and for their comparison with calculated refractograms to determine the refractive index profile in the transition layer based on the tangential model are developed.

  10. Recent studies of the electron cloud induced beam instability at the Los Alamos PSR

    SciTech Connect

    Macek, Robert James; McCrady, Rodney C; Rybarcyk, Lawrence J; Zaugg, Thomas J

    2010-10-06

    Recent beam studies have focused on two aspects of the observed e-p instability at the Los Alamos Proton Storage Ring (PSR). Most recently it has been observed that a stable beam with the standard production bunch width (290 ns injected beam bunch width) will become e-p unstable when the bunch width is shortened to 200 ns or less. This was not the case years earlier when the ring RF operated at the exact 72.000 sub harmonic of the Linac bunch frequency. Experimental characteristics and possible explanations of this recent ''short pulse instability phenomenon'' will be presented. Other beam studies have focused on electron cloud generation, trapping and ejection from quadrupoles and are the focus of another talk. (auth)

  11. Coherent beam-beam interaction with four colliding beams

    NASA Astrophysics Data System (ADS)

    Podobedov, B.; Siemann, R. H.

    1995-09-01

    The coherent beam-beam interaction in the absence of Landau damping is studied with a computer simulation of four space-charge-compensated colliding beams. Results are presented for the modes, phase space structures, widths, and growth rates of coherent beam-beam resonances. These results are compared with solutions of the Vlasov equation, and with measurements made at the Dispositif de Collisions dans l'Igloo (DCI) storage ring in Orsay, France, which operated with space-charge-compensated colliding beams.

  12. A wire calorimeter for the SPIDER beam: Experimental tests and feasibility study

    SciTech Connect

    Pasqualotto, R. Serianni, G.; Veltri, P.; Cervaro, V.; Fasolo, D.; Mario, I.; Zanini, M.

    2015-04-08

    To study and optimize negative ion production and acceleration, in view of the use of neutral beam injectors in the ITER project, the SPIDER test facility (particle energy 100keV; beam current 50A, distributed over 1280 beamlets) is under construction in Padova, with the aim of testing beam characteristics and to verify the source proper operation, by means of several diagnostic systems. An array of tungsten wires, directly exposed to the beam and consequently heated to high temperature, is used in similar experiments at IPP-Garching to study the beam optics, which is one of the most important issues, in a qualitative way. The present contribution gives a description of an experimental investigation of the behavior of tungsten wires under high heat loads in vacuum. Samples of tungsten wires are heated by electrical currents and the emitted light is measured by a camera in the 400-1100nm wavelength range, which is proposed as a calibration tool. Simultaneously, the voltage applied to the wire is measured to study the dependency of emissivity on temperature. The feasibility study of a wire calorimeter for SPIDER is finally proposed; to this purpose, the expected behaviour of tungsten with the two-dimensional beam profile in SPIDER is numerically addressed.

  13. A wire calorimeter for the SPIDER beam: Experimental tests and feasibility study

    NASA Astrophysics Data System (ADS)

    Pasqualotto, R.; Serianni, G.; Mario, I.; Veltri, P.; Zanini, M.; Cervaro, V.; Fasolo, D.

    2015-04-01

    To study and optimize negative ion production and acceleration, in view of the use of neutral beam injectors in the ITER project, the SPIDER test facility (particle energy 100keV; beam current 50A, distributed over 1280 beamlets) is under construction in Padova, with the aim of testing beam characteristics and to verify the source proper operation, by means of several diagnostic systems. An array of tungsten wires, directly exposed to the beam and consequently heated to high temperature, is used in similar experiments at IPP-Garching to study the beam optics, which is one of the most important issues, in a qualitative way. The present contribution gives a description of an experimental investigation of the behavior of tungsten wires under high heat loads in vacuum. Samples of tungsten wires are heated by electrical currents and the emitted light is measured by a camera in the 400-1100nm wavelength range, which is proposed as a calibration tool. Simultaneously, the voltage applied to the wire is measured to study the dependency of emissivity on temperature. The feasibility study of a wire calorimeter for SPIDER is finally proposed; to this purpose, the expected behaviour of tungsten with the two-dimensional beam profile in SPIDER is numerically addressed.

  14. An exploratory study of the relationship between biomechanical factors and right-arm musculoskeletal discomfort and fatigue in a VDT data-entry task.

    PubMed

    Pan, C S; Schleifer, L M

    1996-06-01

    The relationship of key force and keystroke rate with right-arm musculoskeletal discomfort and fatigue was explored in a video-display-terminal (VDT) data-entry task. Forty-three data transcribers entered bogus data from tax forms at a VDT for one workday with their right hand. Peak key force and keystroke rate were monitored on a continuous basis. Self-ratings of right-arm discomfort and fatigue were assessed at periodic intervals. Stepwise regression analyses indicated that both lower key forces and lower keystroke rates were associated with higher ratings of right-elbow discomfort. In addition, lower key forces were associated with higher ratings of right-hand discomfort and lower keystroke rates were associated with higher ratings of right-shoulder discomfort and fatigue. The amount of variance accounted for by these models ranged from 7 to 24%. These results appear to be contrary to conventional biomechanical models that postulate a positive association between key force, keystroke rate and musculoskeletal discomfort in VDT work. Further laboratory and field research under controlled conditions is needed to clarify the direction and extent of the cause-and-effect relationship between biomechanical factors and musculoskeletal discomfort in VDT data-entry work.

  15. Numerical study of super-resolved optical microscopy with partly staggered beams

    NASA Astrophysics Data System (ADS)

    He, Jinping; Wang, Nan; Kobayashi, Takayoshi

    2016-12-01

    The resolving power of optical microscopy involving two or even more beams, such as pump-probe microscopy and nonlinear optical microscopy, can be enhanced both laterally and longitudinally with partly staggered beams. A numerical study of the new super-resolution imaging technology is performed with vector diffraction theory. The influence of polarization is discussed. A resolving power of sub-100 nm and sub-300 nm in the lateral and longitudinal directions, respectively, is achievable.

  16. JINR test facility for studies FEL bunching technique for CLIC driving beam

    SciTech Connect

    Dolbilov, G.V.; Fateev, A.A.; Ivanov, I.N.

    1995-12-31

    SILUND-21 linear induction accelerator (energy up to 10 MeV, peak current about of 1 kA, pulse duration 50 - 70 ns) is constructed at JINR in the framework of experimental program to study free electron laser physics, a problem of two-beam acceleration and microwave electronics. In this paper we present project of an experiment to adopt the FEL bunching technique for generation of the CLIC driving beam.

  17. The biomechanical structure of swim start performance.

    PubMed

    Fischer, Sebastian; Kibele, Armin

    2016-11-01

    The aim of this study was to analyse the significance of various biomechanical parameters in swim start performance for the grab and track start techniques. To do so, structural equation models were analysed, incorporating measurements for the take-off phase, flight phase and entry phase. Forty-six elite German swimmers (18 female and 28 male; age: 20.1 ± 4.2 yrs; PB (100 m Freestyle): 53.6 ± 2.9 s) participated in the study. Their swim start performance was examined within a 25-m sprint test. Structural equation modelling was conducted in separate models for the block time, flight time and water time and in a combined model for swim start time. Our main finding was that swim start time is predominantly related to water time and determined to a lesser extent by block time and flight time. We conclude that more emphasis should be given to the water immersion behaviour and the gliding phase when analysing swim start performance. Furthermore, significant differences were found between the grab start and track techniques as regards the biomechanical parameters representing the take-off phase and water phase.

  18. Modeling the biomechanics of fetal movements.

    PubMed

    Verbruggen, Stefaan W; Loo, Jessica H W; Hayat, Tayyib T A; Hajnal, Joseph V; Rutherford, Mary A; Phillips, Andrew T M; Nowlan, Niamh C

    2016-08-01

    Fetal movements in the uterus are a natural part of development and are known to play an important role in normal musculoskeletal development. However, very little is known about the biomechanical stimuli that arise during movements in utero, despite these stimuli being crucial to normal bone and joint formation. Therefore, the objective of this study was to create a series of computational steps by which the forces generated during a kick in utero could be predicted from clinically observed fetal movements using novel cine-MRI data of three fetuses, aged 20-22 weeks. A custom tracking software was designed to characterize the movements of joints in utero, and average uterus deflection of [Formula: see text] mm due to kicking was calculated. These observed displacements provided boundary conditions for a finite element model of the uterine environment, predicting an average reaction force of [Formula: see text] N generated by a kick against the uterine wall. Finally, these data were applied as inputs for a musculoskeletal model of a fetal kick, resulting in predicted maximum forces in the muscles surrounding the hip joint of approximately 8 N, while higher maximum forces of approximately 21 N were predicted for the muscles surrounding the knee joint. This study provides a novel insight into the closed mechanical environment of the uterus, with an innovative method allowing elucidation of the biomechanical interaction of the developing fetus with its surroundings.

  19. Contribution of biomechanics to clinical practice in orthopaedics.

    PubMed

    Woo, Savio L-Y

    2004-01-01

    clinicians to work together in a seamless manner to solve these complicated problems. As biomechanics is a field to study force and motion of the living, which includes molecules to cells to tissues to organs to the whole body, it has and will continue to be an integral part seeking solutions that will help injured patients to return to their sports activities more quickly and completely.

  20. Energetics, Biomechanics, and Performance in Masters' Swimmers: A Systematic Review.

    PubMed

    Ferreira, Maria I; Barbosa, Tiago M; Costa, Mário J; Neiva, Henrique P; Marinho, Daniel A

    2016-07-01

    Ferreira, MI, Barbosa, TM, Costa, MJ, Neiva, HP, and Marinho, DA. Energetics, biomechanics, and performance in masters' swimmers: a systematic review. J Strength Cond Res 30(7): 2069-2081, 2016-This study aimed to summarize evidence on masters' swimmers energetics, biomechanics, and performance gathered in selected studies. An expanded search was conducted on 6 databases, conference proceedings, and department files. Fifteen studies were selected for further analysis. A qualitative evaluation of the studies based on the Quality Index (QI) was performed by 2 independent reviewers. The studies were thereafter classified into 3 domains according to the reported data: performance (10 studies), energetics (4 studies), and biomechanics (6 studies). The selected 15 articles included in this review presented low QI scores (mean score, 10.47 points). The biomechanics domain obtained higher QI (11.5 points), followed by energetics and performance (10.6 and 9.9 points, respectively). Stroke frequency (SF) and stroke length (SL) were both influenced by aging, although SF is more affected than SL. Propelling efficiency (ηp) decreased with age. Swimming performance declined with age. The performance declines with age having male swimmers deliver better performances than female counterparts, although this difference tends to be narrow in long-distance events. One single longitudinal study is found in the literature reporting the changes in performance over time. The remaining studies are cross-sectional designs focusing on the energetics and biomechanics. Overall, biomechanics parameters, such as SF, SL, and ηp, tend to decrease with age. This review shows the lack of a solid body of knowledge (reflected in the amount and quality of the articles published) on the changes in biomechanics, energetics, and performance of master swimmers over time. The training programs for this age-group should aim to preserve the energetics as much as possible and, concurrently, improve the

  1. Investigation of Crew Restraint System Biomechanics.

    DTIC Science & Technology

    1982-05-01

    46FAMRL-TR-81 -103 SINVESTIGATION OF CREW RESTRAINT SYSTEM BIOMECHANICS NORMWAN S. PHILLIPS ROBERT A. THOMSON IRA B. FISCUS UNIVERSITY OF DA YTON RESEARCH...Escape System Biomechanics 20. ABSTRACT (Continue on reverse side If necessary and identify by block number) .Experimental data were collected and...properties and harness characteristics were included in the model. The analytical model was also used with biomechanical data for the rhesus monkey

  2. Laser ion acceleration toward future ion beam cancer therapy - Numerical simulation study -

    PubMed Central

    Kawata, Shigeo; Izumiyama, Takeshi; Nagashima, Toshihiro; Takano, Masahiro; Barada, Daisuke; Kong, Qing; Gu, Yan Jun; Wang, Ping Xiao; Ma, Yan Yun; Wang, Wei Min

    2013-01-01

    Background: Ion beam has been used in cancer treatment, and has a unique preferable feature to deposit its main energy inside a human body so that cancer cell could be killed by the ion beam. However, conventional ion accelerator tends to be huge in its size and its cost. In this paper a future intense-laser ion accelerator is proposed to make the ion accelerator compact. Subjects and methods: An intense femtosecond pulsed laser was employed to accelerate ions. The issues in the laser ion accelerator include the energy efficiency from the laser to the ions, the ion beam collimation, the ion energy spectrum control, the ion beam bunching and the ion particle energy control. In the study particle computer simulations were performed to solve the issues, and each component was designed to control the ion beam quality. Results: When an intense laser illuminates a target, electrons in the target are accelerated and leave from the target; temporarily a strong electric field is formed between the high-energy electrons and the target ions, and the target ions are accelerated. The energy efficiency from the laser to ions was improved by using a solid target with a fine sub-wavelength structure or by a near-critical density gas plasma. The ion beam collimation was realized by holes behind the solid target. The control of the ion energy spectrum and the ion particle energy, and the ion beam bunching were successfully realized by a multi-stage laser-target interaction. Conclusions: The present study proposed a novel concept for a future compact laser ion accelerator, based on each component study required to control the ion beam quality and parameters. PMID:24155555

  3. Studies of a gas-filled helical muon beam cooling channel

    SciTech Connect

    Yonehara, K.; Derbenev, Y.; Johnson, R.P.; Roberts, T.J.; /MUONS Inc., Batavia

    2006-06-01

    A helical cooling channel (HCC) can quickly reduce the six dimensional phase space of muon beams for muon colliders, neutrino factories, and intense muon sources. The HCC is composed of solenoidal, helical dipole, and helical quadrupole magnetic fields to provide the focusing and dispersion needed for emittance exchange as the beam follows an equilibrium helical orbit through a continuous homogeneous absorber. The beam dynamics of a gas-filled helical muon beam cooling channel is studied by using Monte Carlo simulations. The results verify the cooling theory [1] of the helical magnet. The cooling performance has been improved by correcting chromatic aberration and the non-linear effects caused by the ionization energy loss process. With these improvements, a simulated cooling channel of 160 meters length has achieved a reduction of 6-dimensional (6D) phase space by a factor of 50,000.

  4. Numerical studies of the Weibel Instability in Intense Charged Particle Beams with Large Energy Anisotropy

    NASA Astrophysics Data System (ADS)

    Lee, Wei-Li; Startsev, Edward A.; Davidson, Ronald C.

    2004-11-01

    In intense charged particle beams with large temperature anisotropy free energy is available to drive a transverse electromagnetic Weibel-type instability. The finite transverse geometry of the confined beam makes a detailed theoretical investigation difficult. In this paper the newly developed bEASt (beam eigenmode and spectra) code which solves the linearized Vlasov-Maxwell equations is used to investigate the detailed properties of the Weibel instability for a long charge bunch propagating through a cylindrical pipe of radius r_w. The stability analysis is carried out for azimuthally symmetric perturbations about a two-temperature thermal equilibrium distribution in the smooth-focusing approximation. To study the nonlinear stage of the instability, the Darwin model is being developed and incorporated into the Beam Equilibrium Stability and Transport(BEST) code.

  5. Experimental study of ultrasonic beam sectors for energy conversion into Lamb waves and Rayleigh waves.

    PubMed

    Declercq, Nico Felicien

    2014-02-01

    When a bounded beam is incident on an immersed plate Lamb waves or Rayleigh waves can be generated. Because the amplitude of a bounded beam is not constant along its wave front, a specific beam profile is formed that influences the local efficiency of energy conversion of incident sound into Lamb waves or Rayleigh waves. Understanding this phenomenon is important for ultrasonic immersion experiments of objects because the quality of such experiments highly depends on the amount of energy transmitted into the object. This paper shows by means of experiments based on monochromatic Schlieren photography that the area within the bounded beam responsible for Lamb wave generation differs from that responsible for Rayleigh wave generation. Furthermore it provides experimental verification of an earlier numerical study concerning Rayleigh wave generation.

  6. Studies of the effects of electron cloud formation on beam dynamics at CesrTA

    SciTech Connect

    Crittenden, J. A.; Calvey, J. R.; Dugan, G.; Livezey, J. A.; Kreinick, D.L.; Palmer, M. A.; Rubin, D. L.; Harkay, K.; Holtzapple, R. L.; Ohmi, K.; Furman, M. A.; Penn, G.; Venturini, M.; Pivi, M. T. F.; Wang, L.

    2009-05-01

    The Cornell Electron Storage Ring Test Accelerator (CesrTA) has commenced operation as a linear collider damping ring test bed following its conversion from an e{sup +}e{sup -}-collider in 2008. A core component of the research program is the measurement of effects of synchrotron-radiation-induced electron cloud formation on beam dynamics. We have studied the interaction of the beam with the cloud with measurements of coherent tune shifts and emittance growth in various bunch train configurations, bunch currents, beam energies, and bunch lengths, for both e{sup +} and e{sup -} beams. This paper compares a subset of these measurements to modeling results from the two-dimensional cloud simulation packages ECLOUD and POSINST. These codes each model most of the tune shift measurements with remarkable accuracy, while some comparisons merit further investigation.

  7. Biomechanics of sport concussion: quest for the elusive injury threshold.

    PubMed

    Guskiewicz, Kevin M; Mihalik, Jason P

    2011-01-01

    Previous concussion biomechanics research has relied heavily on the animal model or laboratory reconstruction of concussive injuries captured on video footage. Real-time data collection involves a novel approach to better understanding the medical issues related to sport concussion. Recent studies suggest that a concussive injury threshold is elusive and may, in fact, be irrelevant when predicting the clinical outcome.

  8. The Biomechanical Implications of Obesity in K-12 Learners

    ERIC Educational Resources Information Center

    Strohmeyer, Scott

    2007-01-01

    Few biomechanical studies have examined obese individuals as primary subjects. However, some mechanical differences have been identified between overweight or obese individuals and nonoverweight movers. It is not clear how obesity affects the onset of osteoarthritis, for example, but it is evident that obesity does place significant limitations on…

  9. Lower Extremity Biomechanical Demands During Saut de Chat Leaps.

    PubMed

    Jarvis, Danielle N; Kulig, Kornelia

    2016-12-01

    In dance, high demands are placed on the lower extremity joints during jumping tasks. The purpose of this study was to compare biomechanical demands placed on the lower extremity joints during the takeoff and landing phases of saut de chat leaps.

  10. BEAM-BEAM SIMULATIONS FOR DOUBLE-GAUSSIAN BEAMS.

    SciTech Connect

    MONTAG, C.; MALITSKY, N.; BEN-ZVI, I.; LITVINENKO, V.

    2005-05-16

    Electron cooling together with intra-beam scattering results in a transverse distribution that can best be described by a sum of two gaussians, one for the high-density core and one for the tails of the distribution. Simulation studies are being performed to understand the beam-beam interaction of these double-gaussian beams. Here we report the effect of low-frequency random tune modulations on diffusion in double-gaussian beams and compare the effects to those in beam-beam interactions with regular gaussian beams and identical tune shift parameters.

  11. Integrative Structural Biomechanical Concepts of Ankylosing Spondylitis

    PubMed Central

    Masi, Alfonse T.; Nair, Kalyani; Andonian, Brian J.; Prus, Kristina M.; Kelly, Joseph; Sanchez, Jose R.; Henderson, Jacqueline

    2011-01-01

    Ankylosing spondylitis (AS) is not fully explained by inflammatory processes. Clinical, epidemiological, genetic, and course of disease features indicate additional host-related risk processes and predispositions. Collectively, the pattern of predisposition to onset in adolescent and young adult ages, male preponderance, and widely varied severity of AS is unique among rheumatic diseases. However, this pattern could reflect biomechanical and structural differences between the sexes, naturally occurring musculoskeletal changes over life cycles, and a population polymorphism. During juvenile development, the body is more flexible and weaker than during adolescent maturation and young adulthood, when strengthening and stiffening considerably increase. During middle and later ages, the musculoskeletal system again weakens. The novel concept of an innate axial myofascial hypertonicity reflects basic mechanobiological principles in human function, tissue reactivity, and pathology. However, these processes have been little studied and require critical testing. The proposed physical mechanisms likely interact with recognized immunobiological pathways. The structural biomechanical processes and tissue reactions might possibly precede initiation of other AS-related pathways. Research in the combined structural mechanobiology and immunobiology processes promises to improve understanding of the initiation and perpetuation of AS than prevailing concepts. The combined processes might better explain characteristic enthesopathic and inflammatory processes in AS. PMID:22216409

  12. Biomechanical analysis of jaw-closing movements.

    PubMed

    Koolstra, J H; van Eijden, T M

    1995-09-01

    This study concerns the complex interaction between active muscle forces and passive guiding structures during jaw-closing movements. It is generally accepted that the ligaments of the joint play a major role in condylar guidance during these movements. While these ligaments permit a wide range of motions, it was assumed that they are not primarily involved in force transmission in the joints. Therefore, it was hypothesized that muscle forces and movement constraints caused by the articular surfaces imply a necessary and sufficient condition to generate ordinary jaw-closing movements. This hypothesis was tested by biomechanical analysis. A dynamic six-degrees-of-freedom mathematical model of the human masticatory system has been developed for qualitative analysis of the contributions of the different masticatory muscles to jaw-closing movements, it was found that the normally observed movement, which includes a swing-slide condylar movement along the articular eminence, can be generated by various separate pairs of masticatory muscles, among which the different parts of the masseter as well as the medial pterygoid muscle appeared to be the most suitable to complete this action. The results seem to be in contrast to the general opinion that a muscle with a forward-directed force component may not be suitable for generating jaw movements in which the condyle moves backward. The results can be explained, however, by biomechanical analysis which includes not only muscle and joint forces as used in standard textbooks of anatomy, but also the torques generated by these forces.

  13. Biomechanical consequences of epiphytism in intertidal macroalgae.

    PubMed

    Anderson, Laura M; Martone, Patrick T

    2014-04-01

    Epiphytic algae grow on other algae rather than hard substrata, perhaps circumventing competition for space in marine ecosystems. Aquatic epiphytes are widely thought to negatively affect host fitness; it is also possible that epiphytes benefit from associating with hosts. This study explored the biomechanical costs and benefits of the epiphytic association between the intertidal brown algal epiphyte Soranthera ulvoidea and its red algal host Odonthalia floccosa. Drag on epiphytized and unepiphytized hosts was measured in a recirculating water flume. A typical epiphyte load increased drag on hosts by ~50%, increasing dislodgment risk of epiphytized hosts compared with hosts that did not have epiphytes. However, epiphytes were more likely to dislodge from hosts than hosts were to dislodge from the substratum, suggesting that drag added by epiphytes may not be mechanically harmful to hosts if epiphytes break first. Concomitantly, epiphytes experienced reduced flow when attached to hosts, perhaps allowing them to grow larger or live in more wave-exposed areas. Biomechanical interactions between algal epiphytes and hosts are complex and not necessarily negative, which may partially explain the evolution and persistence of epiphytic relationships.

  14. Biomechanical analysis of traumatic mesenteric avulsion.

    PubMed

    Bège, Thierry; Ménard, Jérémie; Tremblay, Jaelle; Denis, Ronald; Arnoux, Pierre-Jean; Petit, Yvan

    2015-02-01

    Mesenteric avulsion, corresponding to a tearing of intestine's root, generally results from high deceleration in road accidents. The biomechanical analysis of bowel and mesenteric injuries is a major challenge for injury prevention, particularly because seat belt restraint may paradoxically increase their risk of occurrence. The aim of this study was to identify the biomechanical behavior of mesentery and small bowel (MSB) tissue samples under dynamical loading conditions. A dedicated test bench was designed in order to perform tensile tests on fresh MSB porcine specimens, with quasi-static (1 mm/s) and dynamic (100 mm/s) loading conditions. The mechanical behavior of MSB specimens was investigated and compared to isolated mesenteric and isolated small bowel specimens. The results show a high sensitivity of MSB stiffness (1.0 ± 0.2 and 1.3 ± 0.3 N/mm at 1 and 100 mm/s, p = 0.001) and ultimate force (22 ± 5 and 35 ± 8 N at 1 and 100 mm/s, p = 0.001) to the loading rate but not for the displacement at failure. This leads to postulate on a failure criteria based on strain level regardless of the strain rate. These experimental results could be further used to develop refined finite element models and to further investigate on injury mechanisms associated to seat belt restraints, as well as to evaluate and improve protective devices.

  15. Integrated biomechanical and topographical surface characterization (IBTSC)

    NASA Astrophysics Data System (ADS)

    Löberg, Johanna; Mattisson, Ingela; Ahlberg, Elisabet

    2014-01-01

    In an attempt to reduce the need for animal studies in dental implant applications, a new model has been developed which combines well-known surface characterization methods with theoretical biomechanical calculations. The model has been named integrated biomechanical and topographical surface characterization (IBTSC), and gives a comprehensive description of the surface topography and the ability of the surface to induce retention strength with bone. IBTSC comprises determination of 3D-surface roughness parameters by using 3D-scanning electron microscopy (3D-SEM) and atomic force microscopy (AFM), and calculation of the ability of different surface topographies to induce retention strength in bone by using the local model. Inherent in this integrated approach is the use of a length scale analysis, which makes it possible to separate different size levels of surface features. The IBTSC concept is tested on surfaces with different level of hierarchy, induced by mechanical as well as chemical treatment. Sequential treatment with oxalic and hydrofluoric acid results in precipitated nano-sized features that increase the surface roughness and the surface slope on the sub-micro and nano levels. This surface shows the highest calculated shear strength using the local model. The validity, robustness and applicability of the IBTSC concept are demonstrated and discussed.

  16. Temporomandibular joint: disorders, treatments, and biomechanics.

    PubMed

    Ingawalé, Shirish; Goswami, Tarun

    2009-05-01

    Temporomandibular joint (TMJ) is a complex, sensitive, and highly mobile joint. Millions of people suffer from temporomandibular disorders (TMD) in USA alone. The TMD treatment options need to be looked at more fully to assess possible improvement of the available options and introduction of novel techniques. As reconstruction with either partial or total joint prosthesis is the potential treatment option in certain TMD conditions, it is essential to study outcomes of the FDA approved TMJ implants in a controlled comparative manner. Evaluating the kinetics and kinematics of the TMJ enables the understanding of structure and function of normal and diseased TMJ to predict changes due to alterations, and to propose more efficient methods of treatment. Although many researchers have conducted biomechanical analysis of the TMJ, many of the methods have certain limitations. Therefore, a more comprehensive analysis is necessary for better understanding of different movements and resulting forces and stresses in the joint components. This article provides the results of a state-of-the-art investigation of the TMJ anatomy, TMD, treatment options, a review of the FDA approved TMJ prosthetic devices, and the TMJ biomechanics.

  17. A slow positron beam generator for lifetime studies

    NASA Technical Reports Server (NTRS)

    Singh, Jag J.; Eftekhari, Abe; St.clair, Terry L.

    1989-01-01

    A slow positron beam generator using well-annealed polycrystalline tungsten moderators and a Na-22 positron source was developed. A 250 micro c source, deposited on a 2.54 micron thick aluminized mylar, is sandwiched between two (2.54 cm x 2.54 cm x 0.0127 cm) tungsten pieces. Two (2.54 cm x 2.54 cm x t cm) test polymer films insulate the two tungsten moderator pieces from the aluminized mylar source holder (t=0.00127 to 0.0127). A potential difference of 10 to 100 volts--depending on the test polymer film thickness (t)--is applied between the tungsten pieces and the source foil. Thermalized positrons diffusing out of the moderator pieces are attracted to the source foil held at an appropriate potential below the moderator pieces. These positrons have to pass through the test polymer films before they can reach the source foil. The potential difference between the moderator pieces and the aluminized mylar is so adjusted as to force the positrons to stop in the test polymer films. Thus the new generator becomes an effective source of positrons for assaying thin polymer films for their molecular morphology.

  18. Ion Beam Analyses Of Bark And Wood In Environmental Studies

    NASA Astrophysics Data System (ADS)

    Lill, J.-O.; Saarela, K.-E.; Harju, L.; Rajander, J.; Lindroos, A.; Heselius, S.-J.

    2011-06-01

    A large number of wood and bark samples have been analysed utilizing particle-induced X-ray emission (PIXE) and particle-induced gamma-ray emission (PIGE) techniques. Samples of common tree species like Scots Pine, Norway Spruce and birch were collected from a large number of sites in Southern and Southwestern Finland. Some of the samples were from a heavily polluted area in the vicinity of a copper-nickel smelter. The samples were dry ashed at 550 °C for the removal of the organic matrix in order to increase the analytical sensitivity of the method. The sensitivity was enhanced by a factor of 50 for wood and slightly less for bark. The ashed samples were pressed into pellets and irradiated as thick targets with a millimetre-sized proton beam. By including the ashing procedure in the method, the statistical dispersion due to elemental heterogeneities in wood material could be reduced. As a by-product, information about the elemental composition of ashes was obtained. By comparing the concentration of an element in bark ash to the concentration in wood ash of the same tree useful information from environmental point of view was obtained. The obtained ratio of the ashes was used to distinguish between elemental contributions from anthropogenic atmospheric sources and natural geochemical sources, like soil and bedrock.

  19. Photoemission studies using femtosecond pulses for high brightness electron beams

    NASA Astrophysics Data System (ADS)

    Srinivasan-Rao, T.; Tsang, T.; Fischer, J.

    1990-06-01

    We present the results of a series of experiments where various metal photocathodes are irradiated with ultrashort laser pulses, whose characteristics are: (lambda) = 625 nm, (tau) = 100 fs, PRR = 89.5 MHz, H(nu) = 2 eV and average power 25 mW in each of the two beams. The quantum efficiency of the metals range from approximately 10(exp -12) to 10(exp -8) at a power density of 100 MW/sq cm at normal incidence. Since all the electrons are emitted due to multiphoton processes, these efficiencies are expected to increase substantially at large intensities. The efficiency at 100 MW/sq cm was increased by using p-polarized light at oblique incidence by approximately 20 x and by mediating the electron emission through surface plasmon excitation by approximately 10(exp 3) x. For the low intensities used in these experiments, the electron pulse duration is almost the same as the laser pulse duration for both the bulk and the surface plasmon mediated photoemission.

  20. Biomechanical properties of the keratoconic cornea: a review.

    PubMed

    Vellara, Hans R; Patel, Dipika V

    2015-01-01

    There has been a recent surge of interest in assessing corneal biomechanical properties due to potential clinical applications, particularly in the early detection of keratoconus (KC). This review discusses the effects of keratoconus on the biomechanical properties of the cornea and the current techniques used to detect these changes both in the laboratory and clinical setting. Specific structural changes occurring in the corneal stroma as part of the disease process can be linked to alterations in the viscous and elastic properties of the cornea in keratoconus. Although there are extensive ex vivo studies using techniques such as extensometry and inflation testing to analyse the biomechanical properties of the normal cornea, few have investigated the keratoconic cornea using the same methods. There are a number of ex vivo studies that confirm the effectiveness of collagen cross-linking in increasing Young's modulus in healthy corneas. Recently, research has focussed on measuring corneal biomechanical parameters in vivo using two commercially available instruments: the Ocular Response Analyser (ORA) and the CorVis ST (CST). Both instruments analyse the dynamic behaviour of the cornea, when temporarily deformed by an air puff; however, the outputs of these instruments are not directly comparable due to differences in the characteristics of the air puff and output parameters. Studies using these instruments have reported significant differences between keratoconic and healthy corneas; however, neither instrument can currently be used in isolation to reliably diagnose keratoconus. Further research analysing the outputs of these instruments may enhance their diagnostic capabilities.