Sample records for beam-collimation system performance

  1. Cleaning Insertions and Collimation Challenges

    NASA Astrophysics Data System (ADS)

    Redaelli, S.; Appleby, R. B.; Bertarelli, A.; Bruce, R.; Jowett, J. M.; Lechner, A.; Losito, R.

    High-performance collimation systems are essential for operating efficiently modern hadron machine with large beam intensities. In particular, at the LHC the collimation system ensures a clean disposal of beam halos in the superconducting environment. The challenges of the HL-LHC study pose various demanding requests for beam collimation. In this paper we review the present collimation system and its performance during the LHC Run 1 in 2010-2013. Various collimation solutions under study to address the HL-LHC requirements are then reviewed, identifying the main upgrade baseline and pointing out advanced collimation concept for further enhancement of the performance.

  2. Comparison of fan beam, slit-slat and multi-pinhole collimators for molecular breast tomosynthesis.

    PubMed

    van Roosmalen, Jarno; Beekman, Freek J; Goorden, Marlies C

    2018-05-16

    Recently, we proposed and optimized dedicated multi-pinhole molecular breast tomosynthesis (MBT) that images a lightly compressed breast. As MBT may also be performed with other types of collimators, the aim of this paper is to optimize MBT with fan beam and slit-slat collimators and to compare its performance to that of multi-pinhole MBT to arrive at a truly optimized design. Using analytical expressions, we first optimized fan beam and slit-slat collimator parameters to reach maximum sensitivity at a series of given system resolutions. Additionally, we performed full system simulations of a breast phantom containing several tumours for the optimized designs. We found that at equal system resolution the maximum achievable sensitivity increases from pinhole to slit-slat to fan beam collimation with fan beam and slit-slat MBT having on average a 48% and 20% higher sensitivity than multi-pinhole MBT. Furthermore, by inspecting simulated images and applying a tumour-to-background contrast-to-noise (TB-CNR) analysis, we found that slit-slat collimators underperform with respect to the other collimator types. The fan beam collimators obtained a similar TB-CNR as the pinhole collimators, but the optimum was reached at different system resolutions. For fan beam collimators, a 6-8 mm system resolution was optimal in terms of TB-CNR, while with pinhole collimation highest TB-CNR was reached in the 7-10 mm range.

  3. Comparison of fan beam, slit-slat and multi-pinhole collimators for molecular breast tomosynthesis

    NASA Astrophysics Data System (ADS)

    van Roosmalen, Jarno; Beekman, Freek J.; Goorden, Marlies C.

    2018-05-01

    Recently, we proposed and optimized dedicated multi-pinhole molecular breast tomosynthesis (MBT) that images a lightly compressed breast. As MBT may also be performed with other types of collimators, the aim of this paper is to optimize MBT with fan beam and slit-slat collimators and to compare its performance to that of multi-pinhole MBT to arrive at a truly optimized design. Using analytical expressions, we first optimized fan beam and slit-slat collimator parameters to reach maximum sensitivity at a series of given system resolutions. Additionally, we performed full system simulations of a breast phantom containing several tumours for the optimized designs. We found that at equal system resolution the maximum achievable sensitivity increases from pinhole to slit-slat to fan beam collimation with fan beam and slit-slat MBT having on average a 48% and 20% higher sensitivity than multi-pinhole MBT. Furthermore, by inspecting simulated images and applying a tumour-to-background contrast-to-noise (TB-CNR) analysis, we found that slit-slat collimators underperform with respect to the other collimator types. The fan beam collimators obtained a similar TB-CNR as the pinhole collimators, but the optimum was reached at different system resolutions. For fan beam collimators, a 6–8 mm system resolution was optimal in terms of TB-CNR, while with pinhole collimation highest TB-CNR was reached in the 7–10 mm range.

  4. Laser beam projection with adaptive array of fiber collimators. II. Analysis of atmospheric compensation efficiency.

    PubMed

    Lachinova, Svetlana L; Vorontsov, Mikhail A

    2008-08-01

    We analyze the potential efficiency of laser beam projection onto a remote object in atmosphere with incoherent and coherent phase-locked conformal-beam director systems composed of an adaptive array of fiber collimators. Adaptive optics compensation of turbulence-induced phase aberrations in these systems is performed at each fiber collimator. Our analysis is based on a derived expression for the atmospheric-averaged value of the mean square residual phase error as well as direct numerical simulations. Operation of both conformal-beam projection systems is compared for various adaptive system configurations characterized by the number of fiber collimators, the adaptive compensation resolution, and atmospheric turbulence conditions.

  5. Beam feasibility study of a collimator with in-jaw beam position monitors

    NASA Astrophysics Data System (ADS)

    Wollmann, Daniel; Nosych, Andriy A.; Valentino, Gianluca; Aberle, Oliver; Aßmann, Ralph W.; Bertarelli, Alessandro; Boccard, Christian; Bruce, Roderik; Burkart, Florian; Calvo, Eva; Cauchi, Marija; Dallocchio, Alessandro; Deboy, Daniel; Gasior, Marek; Jones, Rhodri; Kain, Verena; Lari, Luisella; Redaelli, Stefano; Rossi, Adriana

    2014-12-01

    At present, the beam-based alignment of the LHC collimators is performed by touching the beam halo with both jaws of each collimator. This method requires dedicated fills at low intensities that are done infrequently and makes this procedure time consuming. This limits the operational flexibility, in particular in the case of changes of optics and orbit configuration in the experimental regions. The performance of the LHC collimation system relies on the machine reproducibility and regular loss maps to validate the settings of the collimator jaws. To overcome these limitations and to allow a continuous monitoring of the beam position at the collimators, a design with jaw-integrated Beam Position Monitors (BPMs) was proposed and successfully tested with a prototype (mock-up) collimator in the CERN SPS. Extensive beam experiments allowed to determine the achievable accuracy of the jaw alignment for single and multi-turn operation. In this paper, the results of these experiments are discussed. The non-linear response of the BPMs is compared to the predictions from electromagnetic simulations. Finally, the measured alignment accuracy is compared to the one achieved with the present collimators in the LHC.

  6. Beam halo collimation in heavy ion synchrotrons

    NASA Astrophysics Data System (ADS)

    Strašík, I.; Prokhorov, I.; Boine-Frankenheim, O.

    2015-08-01

    This paper presents a systematic study of the halo collimation of ion beams from proton up to uranium in synchrotrons. The projected Facility for Antiproton and Ion Research synchrotron SIS100 is used as a reference case. The concepts are separated into fully stripped (e.g., 238U92+ ) and partially stripped (e.g., 238U28+ ) ion collimation. An application of the two-stage betatron collimation system, well established for proton accelerators, is intended also for fully stripped ions. The two-stage system consists of a primary collimator (a scattering foil) and secondary collimators (bulky absorbers). Interaction of the particles with the primary collimator (scattering, momentum losses, and nuclear interactions) was simulated by using fluka. Particle-tracking simulations were performed by using mad-x. Finally, the dependence of the collimation efficiency on the primary ion species was determined. The influence of the collimation system adjustment, lattice imperfections, and beam parameters was estimated. The concept for the collimation of partially stripped ions employs a thin stripping foil in order to change their charge state. These ions are subsequently deflected towards a dump location using a beam optical element. The charge state distribution after the stripping foil was obtained from global. The ions were tracked by using mad-x.

  7. Design and implementation of a crystal collimation test stand at the Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Mirarchi, D.; Hall, G.; Redaelli, S.; Scandale, W.

    2017-06-01

    Future upgrades of the CERN Large Hadron Collider (LHC) demand improved cleaning performance of its collimation system. Very efficient collimation is required during regular operations at high intensities, because even a small amount of energy deposited on superconducting magnets can cause an abrupt loss of superconducting conditions (quench). The possibility to use a crystal-based collimation system represents an option for improving both cleaning performance and impedance compared to the present system. Before relying on crystal collimation for the LHC, a demonstration under LHC conditions (energy, beam parameters, etc.) and a comparison against the present system is considered mandatory. Thus, a prototype crystal collimation system has been designed and installed in the LHC during the Long Shutdown 1 (LS1), to perform feasibility tests during the Run 2 at energies up to 6.5 TeV. The layout is suitable for operation with proton as well as heavy ion beams. In this paper, the design constraints and the solutions proposed for this test stand for feasibility demonstration of crystal collimation at the LHC are presented. The expected cleaning performance achievable with this test stand, as assessed in simulations, is presented and compared to that of the present LHC collimation system. The first experimental observation of crystal channeling in the LHC at the record beam energy of 6.5 TeV has been obtained in 2015 using the layout presented (Scandale et al., Phys Lett B 758:129, 2016). First tests to measure the cleaning performance of this test stand have been carried out in 2016 and the detailed data analysis is still on-going.

  8. Radiation beam collimation system and method

    DOEpatents

    Schmidt, Oliver A.; Ramanathan, Mohan

    2015-08-18

    The invention provides a method for collimating a radiation beam, the method comprising subjecting the beam to a collimator that yaws and pitches, either separately or simultaneously relative to the incident angle of the beam. Also provided is a system for collimating radiation beams, the system comprising a collimator body, and a stage for pitching and yawing the body. A feature of the invention is that a single, compact mask body defines one or a plurality of collimators having no moving surfaces relative to each other, whereby the entire mask body is moved about a point in space to provide various collimator opening dimensions to oncoming radiation beams.

  9. Numerical simulations of a proposed hollow electron beam collimator for the LHC upgrade at CERN.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Previtali, V.; Stancari, G.; Valishev, A.

    2013-07-12

    In the last years the LHC collimation system has been performing over the expectations, providing the machine with a nearly perfect e cient cleaning system[1]. Nonetheless, when trying to push the existing accelerators to - and over - their design limits, all the accelerator components are required to boost their performances. In particular, in view of the high luminosity frontier for the LHC, the increased intensity would ask for a more e cient cleaning system. In this framework innovative collimation solutions are under evaluation[2]: one option is the usage of an hollow electron lens for beam halo cleaning. This workmore » intends to study the applicability of an the hollow electron lens for the LHC collimation, by evaluating the case of the existing Tevatron e-lens applied to the nominal LHC 7 TeV beam. New e-lens operation modes are here proposed to standard enhance the electron lens halo removal e ect.« less

  10. A conceptual solution for a beam halo collimation system for the Future Circular hadron-hadron Collider (FCC-hh)

    NASA Astrophysics Data System (ADS)

    Fiascaris, M.; Bruce, R.; Redaelli, S.

    2018-06-01

    We present the first conceptual solution for a collimation system for the hadron-hadron option of the Future Circular Collider (FCC-hh). The collimation layout is based on the scaling of the present Large Hadron Collider collimation system to the FCC-hh energy and it includes betatron and momentum cleaning, as well as dump protection collimators and collimators in the experimental insertions for protection of the final focus triplet magnets. An aperture model for the FCC-hh is defined and the geometrical acceptance is calculated at injection and collision energy taking into account mechanical and optics imperfections. The performance of the system is then assessed through the analysis of normalized halo distributions and complete loss maps for an ideal lattice. The performance limitations are discussed and a solution to improve the system performance with the addition of dispersion suppression collimators around the betatron cleaning insertion is presented.

  11. Dose characteristics of in-house-built collimators for stereotactic radiotherapy with a linear accelerator.

    PubMed

    Norrgård, F S; Sipilä, P M; Kulmala, J A; Minn, H R

    1998-06-01

    Dose characteristics of a stereotactic radiotherapy unit based on a standard Varian Clinac 4/100 4 MV linear accelerator, in-house-built Lipowitz collimators and the SMART stereotactic radiotherapy treatment planning software have been determined. Beam collimation is constituted from the standard collimators of the linear accelerator and a tertiary collimation consisting of a replaceable divergent Lipowitz collimator. Four collimators with isocentre diameters of 15, 25, 35 and 45 mm, respectively, were constructed. Beam characteristics were measured in air, acrylic or water with ionization chamber, photon diode, electron diode, diamond detector and film. Monte Carlo simulation was also applied. The radiation leakage under the collimators was less than 1% at 50 mm depth in water. Specific beam characteristics for each collimator were imported to SMART and dose planning with five non-coplanar converging 140 degrees arcs separated by 36 degrees angles was performed for treatment of a RANDO phantom. Dose verification was made with TLD and radiochromic film. The in-house-built collimators were found to be suitable for stereotactic radiotherapy and patient treatments with this system are in progress.

  12. An empirical model for calculation of the collimator contamination dose in therapeutic proton beams

    NASA Astrophysics Data System (ADS)

    Vidal, M.; De Marzi, L.; Szymanowski, H.; Guinement, L.; Nauraye, C.; Hierso, E.; Freud, N.; Ferrand, R.; François, P.; Sarrut, D.

    2016-02-01

    Collimators are used as lateral beam shaping devices in proton therapy with passive scattering beam lines. The dose contamination due to collimator scattering can be as high as 10% of the maximum dose and influences calculation of the output factor or monitor units (MU). To date, commercial treatment planning systems generally use a zero-thickness collimator approximation ignoring edge scattering in the aperture collimator and few analytical models have been proposed to take scattering effects into account, mainly limited to the inner collimator face component. The aim of this study was to characterize and model aperture contamination by means of a fast and accurate analytical model. The entrance face collimator scatter distribution was modeled as a 3D secondary dose source. Predicted dose contaminations were compared to measurements and Monte Carlo simulations. Measurements were performed on two different proton beam lines (a fixed horizontal beam line and a gantry beam line) with divergent apertures and for several field sizes and energies. Discrepancies between analytical algorithm dose prediction and measurements were decreased from 10% to 2% using the proposed model. Gamma-index (2%/1 mm) was respected for more than 90% of pixels. The proposed analytical algorithm increases the accuracy of analytical dose calculations with reasonable computation times.

  13. Wakefields in SLAC linac collimators

    DOE PAGES

    Novokhatski, A.; Decker, F. -J.; Smith, H.; ...

    2014-12-02

    When a beam travels near collimator jaws, it gets an energy loss and a transverse kick due to the backreaction of the beam field diffracted from the jaws. The effect becomes very important for an intense short bunch when a tight collimation of the background beam halo is required. In the Linac Coherent Light Source at SLAC a collimation system is used to protect the undulators from radiation due to particles in the beam halo. The halo is most likely formed from gun dark current or dark current in some of the accelerating sections. However, collimators are also responsible formore » the generation of wake fields. The wake field effect from the collimators not only brings an additional energy jitter and change in the trajectory of the beam, but it also rotates the beam on the phase plane, which consequently leads to a degradation of the performance of the Free Electron Laser at the Linac Coherent Light Source. In this paper, we describe a model of the wake field radiation in the SLAC linac collimators. We use the results of a numerical simulation to illustrate the model. Based on the model, we derive simple formulas for the bunch energy loss and the average kick. We also present results from experimental measurements that confirm our model.« less

  14. Design of a Multi-Pinhole Collimator for I-123 DaTscan Imaging on Dual-Headed SPECT Systems in Combination with a Fan-Beam Collimator.

    PubMed

    King, Michael A; Mukherjee, Joyeeta M; Könik, Arda; Zubal, I George; Dey, Joyoni; Licho, Robert

    2016-02-01

    For the 2011 FDA approved Parkinson's Disease (PD) SPECT imaging agent I-123 labeled DaTscan, the volume of interest (VOI) is the interior portion of the brain. However imaging of the occipital lobe is also required with PD for calculation of the striatal binding ratio (SBR), a parameter of significance in early diagnosis, differentiation of PD from other disorders with similar clinical presentations, and monitoring progression. Thus we propose the usage of a combination of a multi-pinhole (MPH) collimator on one head of the SPECT system and a fan-beam on the other. The MPH would be designed to provide high resolution and sensitivity for imaging of the interior portion of the brain. The fan-beam collimator would provide lower resolution but complete sampling of the brain addressing data sufficiency and allowing a volume-of-interest to be defined over the occipital lobe for calculation of SBR's. Herein we focus on the design of the MPH component of the combined system. Combined reconstruction will be addressed in a subsequent publication. An analysis of 46 clinical DaTscan studies was performed to provide information to define the VOI, and design of a MPH collimator to image this VOI. The system spatial resolution for the MPH was set to 4.7 mm, which is comparable to that of clinical PET systems, and significantly smaller than that of fan-beam collimators employed in SPECT. With this set, we compared system sensitivities for three aperture array designs, and selected the 3 × 3 array due to it being the highest of the three. The combined sensitivity of the apertures for it was similar to that of an ultra-high resolution fan-beam (LEUHRF) collimator, but smaller than that of a high-resolution fan-beam collimator (LEHRF). On the basis of these results we propose the further exploration of this design through simulations, and the development of combined MPH and fan-beam reconstruction.

  15. Measured and simulated heavy-ion beam loss patterns at the CERN Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Hermes, P. D.; Bruce, R.; Jowett, J. M.; Redaelli, S.; Salvachua Ferrando, B.; Valentino, G.; Wollmann, D.

    2016-05-01

    The Large Hadron Collider (LHC) at CERN pushes forward to new regimes in terms of beam energy and intensity. In view of the combination of very energetic and intense beams together with sensitive machine components, in particular the superconducting magnets, the LHC is equipped with a collimation system to provide protection and intercept uncontrolled beam losses. Beam losses could cause a superconducting magnet to quench, or in the worst case, damage the hardware. The collimation system, which is optimized to provide a good protection with proton beams, has shown a cleaning efficiency with heavy-ion beams which is worse by up to two orders of magnitude. The reason for this reduced cleaning efficiency is the fragmentation of heavy-ion beams into isotopes with a different mass to charge ratios because of the interaction with the collimator material. In order to ensure sufficient collimation performance in future ion runs, a detailed theoretical understanding of ion collimation is needed. The simulation of heavy-ion collimation must include processes in which 82 + 208Pb ions fragment into dozens of new isotopes. The ions and their fragments must be tracked inside the magnetic lattice of the LHC to determine their loss positions. This paper gives an overview of physical processes important for the description of heavy-ion loss patterns. Loss maps simulated by means of the two tools ICOSIM [1,2] and the newly developed STIER (SixTrack with Ion-Equivalent Rigidities) are compared with experimental data measured during LHC operation. The comparison shows that the tool STIER is in better agreement.

  16. Loss Control and Collimation for the LHC

    NASA Astrophysics Data System (ADS)

    Burkhardt, H.

    2005-06-01

    The total energy stored in the LHC is expected to reach 360 Mega Joule, which is about two orders of magnitude higher than in HERA or the Tevatron. Damage and quench protection in the LHC require a highly efficient and at the same time very robust collimation system. The currently planned system, the status of the project and the expected performance of the collimation system from injection up to operation with colliding beams will be presented.

  17. BPM Design and Impedance Considerations for a Rotatable Collimator for the LHC Collimation Upgrade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Jeffrey Claiborne; /SLAC; Keller, Lewis

    2010-08-26

    The Phase II upgrade to the LHC collimation system calls for complementing the 30 high robust Phase I graphite secondary collimators with 30 high Z Phase II collimators. This paper reports on BPM and impedance considerations and measurements of the integrated BPMs in the prototype rotatable collimator to be installed in the Super Proton Synchrotron (SPS) at CERN. The BPMs are necessary to align the jaws with the beam. Without careful design the beam impedance can result in unacceptable heating of the chamber wall or beam instabilities. The impedance measurements involve utilizing both a single displaced wire and two wiresmore » excited in opposite phase to disentangle the driving and detuning transverse impedances. Trapped mode resonances and longitudinal impedance are to also be measured and compared with simulations. These measurements, when completed, will demonstrate the device is fully operational and has the impedance characteristics and BPM performance acceptable for installation in the SPS.« less

  18. A neutral-beam profile monitor with a phosphor screen and a high-sensitivity camera for the J-PARC KOTO experiment

    NASA Astrophysics Data System (ADS)

    Matsumura, T.; Kamiji, I.; Nakagiri, K.; Nanjo, H.; Nomura, T.; Sasao, N.; Shinkawa, T.; Shiomi, K.

    2018-03-01

    We have developed a beam-profile monitor (BPM) system to align the collimators for the neutral beam-line at the Hadron Experimental Facility of J-PARC. The system is composed of a phosphor screen and a CCD camera coupled to an image intensifier mounted on a remote control X- Y stage. The design and detailed performance studies of the BPM are presented. The monitor has a spatial resolution of better than 0.6 mm and a deviation from linearity of less than 1%. These results indicate that the BPM system meets the requirements to define collimator-edge positions for the beam-line tuning. Confirmation using the neutral beam for the KOTO experiment is also presented.

  19. Electron radiography

    DOEpatents

    Merrill, Frank E.; Morris, Christopher

    2005-05-17

    A system capable of performing radiography using a beam of electrons. Diffuser means receive a beam of electrons and diffuse the electrons before they enter first matching quadrupoles where the diffused electrons are focused prior to the diffused electrons entering an object. First imaging quadrupoles receive the focused diffused electrons after the focused diffused electrons have been scattered by the object for focusing the scattered electrons. Collimator means receive the scattered electrons and remove scattered electrons that have scattered to large angles. Second imaging quadrupoles receive the collimated scattered electrons and refocus the collimated scattered electrons and map the focused collimated scattered electrons to transverse locations on an image plane representative of the electrons' positions in the object.

  20. Quantitative Single-Ion Irradiation by ASIPP Microbeam

    NASA Astrophysics Data System (ADS)

    Wang, Xu-Fei; Chen, Lian-Yun; Hu, Zhi-Wen; Wang, Xiao-Hua; Zhang, Jun; Li, Jun; Chen, Bin; Hu, Su-Hua; Shi, Zhong-Tao; Wu, Yu; Xu, Ming-Liang; Wu, Li-Jun; Wang, Shao-Hu; Yu, Zeng-Liang

    2004-05-01

    A single-ion microbeam facility has been constructed by the microbeam research group in ASIPP (Institute of Plasma Physics, Chinese Academy of Science). The system was designed to deliver defined numbers of hydrogen ions produced by a van de Graaff accelerator, covering an energy range from 200 keV to 3 MeV, into living cells (5 mum-20 mum diameter) growing in culture on thin plastic films. The beam is collimated by a 1- mum inner diameter HPLC (high performance liquid chromatography) capillary, which forms the micron-dimensional beam-line exit. A microbeam collimator, a scintillation ion counting system and a fast beam shutter, which constitute a precise dosage measuring and controlling system, jointly perform quantitative single-ion irradiation. With this facility, we can presently acquire ion-hitting efficiency close to 95%.

  1. Comparative efficiency analysis of fiber-array and conventional beam director systems in volume turbulence.

    PubMed

    Vorontsov, Mikhail; Filimonov, Grigory; Ovchinnikov, Vladimir; Polnau, Ernst; Lachinova, Svetlana; Weyrauch, Thomas; Mangano, Joseph

    2016-05-20

    The performance of two prominent laser beam projection system types is analyzed through wave-optics numerical simulations for various atmospheric turbulence conditions, propagation distances, and adaptive optics (AO) mitigation techniques. Comparisons are made between different configurations of both a conventional beam director (BD) using a monolithic-optics-based Cassegrain telescope and a fiber-array BD that uses an array of densely packed fiber collimators. The BD systems considered have equal input power and aperture diameters. The projected laser beam power inside the Airy size disk at the target plane is used as the performance metric. For the fiber-array system, both incoherent and coherent beam combining regimes are considered. We also present preliminary results of side-by-side atmospheric beam projection experiments over a 7-km propagation path using both the AO-enhanced beam projection system with a Cassegrain telescope and the coherent fiber-array BD composed of 21 densely packed fiber collimators. Both wave-optics numerical simulation and experimental results demonstrate that, for similar system architectures and turbulence conditions, coherent fiber-array systems are more efficient in mitigation of atmospheric turbulence effects and generation of a hit spot of the smallest possible size on a remotely located target.

  2. Collimation system design for beam loss localization with slipstacking injection in the Fermilab Main Injector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Drozhdin, A.I.; Brown, B.C.; Johnson, D.E.

    2007-06-01

    Results of modeling with the 3-D STRUCT and MARS15 codes of beam loss localization and related radiation effects are presented for the slipstacking injection to the Fermilab Main Injector. Simulations of proton beam loss are done using multi-turn tracking with realistic accelerator apertures, nonlinear fields in the accelerator magnets and time function of the RF manipulations to explain the results of beam loss measurements. The collimation system consists of one primary and four secondary collimators. It intercepts a beam power of 1.6 kW at a scraping rate of 5% of 5.5E+13 ppp, with a beam loss rate in the ringmore » outside the collimation region of 1 W/m or less. Based on thorough energy deposition and radiation modeling, a corresponding collimator design was developed that satisfies all the radiation and engineering constraints.« less

  3. Influence of detector collimation and beam pitch for identification and image quality of ground-glass attenuation and nodules on 16- and 64-detector row CT systems: experimental study using chest phantom.

    PubMed

    Ohno, Yoshiharu; Koyama, Hisanobu; Kono, Astushi; Terada, Mari; Inokawa, Hiroyasu; Matsumoto, Sumiaki; Sugimura, Kazuro

    2007-12-01

    The purpose of the present study was to determine the influence of detector collimation and beam pitch for identification and image quality of ground-glass attenuation (GGA) and nodules on 16- and 64-detector row CTs, by using a commercially available chest phantom. A chest CT phantom including simulated GGAs and nodules was scanned with different detector collimations, beam pitches and tube currents. The probability and image quality of each simulated abnormality was visually assessed with a five-point scoring system. ROC-analysis and ANOVA were then performed to compare the identification and image quality of either protocol with standard values. Detection rates of low-dose CTs were significantly reduced when tube currents were set at 40mA or less by using detector collimation 16 and 64x0.5mm and 16 and 32mmx1.0mm for low pitch, and at 100mA or less by using detector collimation 16 and 64x0.5mm and 16 and 32mmx1.0mm for high pitch (p<0.05). Image qualities of low-dose CTs deteriorated significantly when tube current was set at 100mA or less by using detector collimation 16 and 64x0.5mm and 16 and 32x1.0mm for low pitch, and at 150mA or less by using detector collimation 16 and 64x0.5mm and 16 and 32x1.0mm for high pitch (p<0.05). Detector collimation and beam pitch were important factors for the image quality and identification of GGA and nodules by 16- and 64-detector row CT.

  4. Microbial UV fluence-response assessment using a novel UV-LED collimated beam system.

    PubMed

    Bowker, Colleen; Sain, Amanda; Shatalov, Max; Ducoste, Joel

    2011-02-01

    A research study has been performed to determine the ultraviolet (UV) fluence-response of several target non-pathogenic microorganisms to UV light emitting diodes (UV-LEDs) by performing collimated beam tests. UV-LEDs do not contain toxic mercury, offer design flexibility due to their small size, and have a longer operational life than mercury lamps. Comsol Multiphysics was utilized to create an optimal UV-LED collimated beam design based on number and spacing of UV-LEDs and distance of the sample from the light source while minimizing the overall cost. The optimized UV-LED collimated beam apparatus and a low-pressure mercury lamp collimated beam apparatus were used to determine the UV fluence-response of three surrogate microorganisms (Escherichia coli, MS-2, T7) to 255 nm UV-LEDs, 275 nm UV-LEDs, and 254 nm low-pressure mercury lamps. Irradiation by low-pressure mercury lamps produced greater E. coli and MS-2 inactivation than 255 nm and 275 nm UV-LEDs and similar T7 inactivation to irradiation by 275 nm UV-LEDs. The 275 nm UV-LEDs produced more efficient T7 and E. coli inactivation than 255 nm UV-LEDs while both 255 nm and 275 nm UV-LEDs produced comparable microbial inactivation for MS-2. Differences may have been caused by a departure from the time-dose reciprocity law due to microbial repair mechanisms. Copyright © 2010 Elsevier Ltd. All rights reserved.

  5. Computational Analysis Supporting the Design of a New Beamline for the Mines Neutron Radiography Facility

    NASA Astrophysics Data System (ADS)

    Wilson, C.; King, J.

    The Colorado School of Mines installed a neutron radiography system at the United States Geological Survey TRIGA reactor in 2012. An upgraded beamline could dramatically improve the imaging capabilities of this system. This project performed computational analyses to support the design of a new beamline, with the major goals of minimizing beam divergence and maximizing beam intensity. The new beamline will consist of a square aluminum tube with an 11.43 cm (4.5 in) inner side length and 0.635 cm (0.25 in) thick walls. It is the same length as the original beam tube (8.53 m) and is composed of 1.22 m (4 ft) and 1.52 m (5 ft) flanged sections which bolt together. The bottom 1.22 m of the beamline is a cylindrical aluminum pre-collimator which is 0.635 cm (0.25 in) thick, with an inner diameter of 5.08 cm (2 in). Based on Monte Carlo model results, when a pre-collimator is present, the use of a neutron absorbing liner on the inside surface of the beam tube has almost no effect on the angular distribution of the neutron current at the collimator exit. The use of a pre-collimator may result in a non-uniform flux profile at the image plane; however, as long as the collimator is at least three times longer than the pre-collimator, the flux distortion is acceptably low.

  6. Thermomechanical assessment of the effects of a jaw-beam angle during beam impact on Large Hadron Collider collimators

    NASA Astrophysics Data System (ADS)

    Cauchi, Marija; Assmann, R. W.; Bertarelli, A.; Carra, F.; Lari, L.; Rossi, A.; Mollicone, P.; Sammut, N.

    2015-02-01

    The correct functioning of a collimation system is crucial to safely and successfully operate high-energy particle accelerators, such as the Large Hadron Collider (LHC). However, the requirements to handle high-intensity beams can be demanding, and accident scenarios must be well studied in order to assess if the collimator design is robust against possible error scenarios. One of the catastrophic, though not very probable, accident scenarios identified within the LHC is an asynchronous beam dump. In this case, one (or more) of the 15 precharged kicker circuits fires out of time with the abort gap, spraying beam pulses onto LHC machine elements before the machine protection system can fire the remaining kicker circuits and bring the beam to the dump. If a proton bunch directly hits a collimator during such an event, severe beam-induced damage such as magnet quenches and other equipment damage might result, with consequent downtime for the machine. This study investigates a number of newly defined jaw error cases, which include angular misalignment errors of the collimator jaw. A numerical finite element method approach is presented in order to precisely evaluate the thermomechanical response of tertiary collimators to beam impact. We identify the most critical and interesting cases, and show that a tilt of the jaw can actually mitigate the effect of an asynchronous dump on the collimators. Relevant collimator damage limits are taken into account, with the aim to identify optimal operational conditions for the LHC.

  7. Final implementation, commissioning, and performance of embedded collimator beam position monitors in the Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Valentino, Gianluca; Baud, Guillaume; Bruce, Roderik; Gasior, Marek; Mereghetti, Alessio; Mirarchi, Daniele; Olexa, Jakub; Redaelli, Stefano; Salvachua, Belen; Valloni, Alessandra; Wenninger, Jorg

    2017-08-01

    During Long Shutdown 1, 18 Large Hadron Collider (LHC) collimators were replaced with a new design, in which beam position monitor (BPM) pick-up buttons are embedded in the collimator jaws. The BPMs provide a direct measurement of the beam orbit at the collimators, and therefore can be used to align the collimators more quickly than using the standard technique which relies on feedback from beam losses. Online orbit measurements also allow for reducing operational margins in the collimation hierarchy placed specifically to cater for unknown orbit drifts, therefore decreasing the β* and increasing the luminosity reach of the LHC. In this paper, the results from the commissioning of the embedded BPMs in the LHC are presented. The data acquisition and control software architectures are reviewed. A comparison with the standard alignment technique is provided, together with a fill-to-fill analysis of the measured orbit in different machine modes, which will also be used to determine suitable beam interlocks for a tighter collimation hierarchy.

  8. Calculations of safe collimator settings and β* at the CERN Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Bruce, R.; Assmann, R. W.; Redaelli, S.

    2015-06-01

    The first run of the Large Hadron Collider (LHC) at CERN was very successful and resulted in important physics discoveries. One way of increasing the luminosity in a collider, which gave a very significant contribution to the LHC performance in the first run and can be used even if the beam intensity cannot be increased, is to decrease the transverse beam size at the interaction points by reducing the optical function β*. However, when doing so, the beam becomes larger in the final focusing system, which could expose its aperture to beam losses. For the LHC, which is designed to store beams with a total energy of 362 MJ, this is critical, since the loss of even a small fraction of the beam could cause a magnet quench or even damage. Therefore, the machine aperture has to be protected by the collimation system. The settings of the collimators constrain the maximum beam size that can be tolerated and therefore impose a lower limit on β*. In this paper, we present calculations to determine safe collimator settings and the resulting limit on β*, based on available aperture and operational stability of the machine. Our model was used to determine the LHC configurations in 2011 and 2012 and it was found that β* could be decreased significantly compared to the conservative model used in 2010. The gain in luminosity resulting from the decreased margins between collimators was more than a factor 2, and a further contribution from the use of realistic aperture estimates based on measurements was almost as large. This has played an essential role in the rapid and successful accumulation of experimental data in the LHC.

  9. Design and dosimetry of small animal radiation facilities

    NASA Astrophysics Data System (ADS)

    Rodriguez, Manuel R.

    The aim of this work was to develop an irradiation system for radiobiology studies. We designed a novel image-guided micro-irradiator capable of partial-body zebrafish embryo irradiation. The radiation source is a 50 kV photon beam from a miniature x-ray source (Xoft Inc., CA). The source is inserted in a cylindrical brass collimator, 3 cm in diameter and 3 cm in length. The collimator has a 1 mm-diameter pinhole along the longitudinal axis, which provides a well-focused beam with a sharp penumbra. A photodiode is installed at one exit of the pinhole collimator to monitor the photon dose rate. The source with the collimator is attached under a movable table. A video camera, connected to the computer, is placed above the movable table to record position of the specimens in relation to the pinhole collimator. The captured images are analyzed, and the relative distances between the specimens and the pinhole are calculated. The coordinates are sent to the computer-controlled movable table to accurately position the specimens in the beam. Monte Carlo simulations were performed to characterize dosimetric properties of the system, to determine dosimetric sensitivity, and to help in the design. The image-guidance and high precision of the movable table enable very accurate specimen position. The beam monitoring system provides accurate, fast and easy dose determination. Portability and self-shielding make this system suitable for any radiobiology laboratory. This novel micro-irradiator is appropriate for partial irradiation of zebrafish embryos; however its potential use is much wider like irradiation of cell cultures or other small specimens.

  10. Thermostructural characterization and structural elastic property optimization of novel high luminosity LHC collimation materials at CERN

    NASA Astrophysics Data System (ADS)

    Borg, M.; Bertarelli, A.; Carra, F.; Gradassi, P.; Guardia-Valenzuela, J.; Guinchard, M.; Izquierdo, G. Arnau; Mollicone, P.; Sacristan-de-Frutos, O.; Sammut, N.

    2018-03-01

    The CERN Large Hadron Collider is currently being upgraded to operate at a stored beam energy of 680 MJ through the High Luminosity upgrade. The LHC performance is dependent on the functionality of beam collimation systems, essential for safe beam cleaning and machine protection. A dedicated beam experiment at the CERN High Radiation to Materials facility is created under the HRMT-23 experimental campaign. This experiment investigates the behavior of three collimation jaws having novel composite absorbers made of copper diamond, molybdenum carbide graphite, and carbon fiber carbon, experiencing accidental scenarios involving the direct beam impact on the material. Material characterization is imperative for the design, execution, and analysis of such experiments. This paper presents new data and analysis of the thermostructural characteristics of some of the absorber materials commissioned within CERN facilities. In turn, characterized elastic properties are optimized through the development and implementation of a mixed numerical-experimental optimization technique.

  11. Verification of passive cooling techniques in the Super-FRS beam collimators

    NASA Astrophysics Data System (ADS)

    Douma, C. A.; Gellanki, J.; Najafi, M. A.; Moeini, H.; Kalantar-Nayestanaki, N.; Rigollet, C.; Kuiken, O. J.; Lindemulder, M. F.; Smit, H. A. J.; Timersma, H. J.

    2016-08-01

    The Super FRagment Separator (Super-FRS) at the FAIR facility will be the largest in-flight separator of heavy ions in the world. One of the essential steps in the separation procedure is to stop the unwanted ions with beam collimators. In one of the most common situations, the heavy ions are produced by a fission reaction of a primary 238U-beam (1.5 GeV/u) hitting a 12C target (2.5 g/cm2). In this situation, some of the produced ions are highly charged states of 238U. These ions can reach the collimators with energies of up to 1.3 GeV/u and a power of up to 500 W. Under these conditions, a cooling system is required to prevent damage to the collimators and to the corresponding electronics. Due to the highly radioactive environment, both the collimators and the cooling system must be suitable for robot handling. Therefore, an active cooling system is undesirable because of the increased possibility of malfunctioning and other complications. By using thermal simulations (performed with NX9 of Siemens PLM), the possibility of passive cooling is explored. The validity of these simulations is tested by independent comparison with other simulation programs and by experimental verification. The experimental verification is still under analysis, but preliminary results indicate that the explored passive cooling option provides sufficient temperature reduction.

  12. Inverse-collimated proton radiography for imaging thin materials

    NASA Astrophysics Data System (ADS)

    Freeman, Matthew S.; Allison, Jason; Andrews, Malcolm; Ferm, Eric; Goett, John J.; Kwiatkowski, Kris; Lopez, Julian; Mariam, Fesseha; Marr-Lyon, Mark; Martinez, Michael; Medina, Jason; Medina, Patrick; Merrill, Frank E.; Morris, Chris L.; Murray, Matthew M.; Nedrow, Paul; Neukirch, Levi P.; Prestridge, Katherine; Rigg, Paolo; Saunders, Alexander; Schurman, Tamsen; Tainter, Amy; Trouw, Frans; Tupa, Dale; Tybo, Josh; Vogan-McNeil, Wendy; Wilde, Carl

    2017-01-01

    Relativistic, magnetically focused proton radiography was invented at Los Alamos National Laboratory using the 800 MeV LANSCE beam and is inherently well-suited to imaging dense objects, at areal densities >20 g cm-2. However, if the unscattered portion of the transmitted beam is removed at the Fourier plane through inverse-collimation, this system becomes highly sensitive to very thin media, of areal densities <100 mg cm-2. Here, this inverse-collimation scheme is described in detail and demonstrated by imaging Xe gas with a shockwave generated by an aluminum plate compressing the gas at Mach 8.8. With a 5-mrad inverse collimator, an areal density change of just 49 mg cm-2 across the shock front is discernible with a contrast-to-noise ratio of 3. Geant4 modeling of idealized and realistic proton transports can guide the design of inverse-collimators optimized for specific experimental conditions and show that this technique performs better for thin targets with reduced incident proton beam emittance. This work increases the range of areal densities to which the system is sensitive to span from ˜25 mg cm-2 to 100 g cm-2, exceeding three orders of magnitude. This enables the simultaneous imaging of a dense system as well as thin jets and ejecta material that are otherwise difficult to characterize with high-energy proton radiography.

  13. Inverse-collimated proton radiography for imaging thin materials.

    PubMed

    Freeman, Matthew S; Allison, Jason; Andrews, Malcolm; Ferm, Eric; Goett, John J; Kwiatkowski, Kris; Lopez, Julian; Mariam, Fesseha; Marr-Lyon, Mark; Martinez, Michael; Medina, Jason; Medina, Patrick; Merrill, Frank E; Morris, Chris L; Murray, Matthew M; Nedrow, Paul; Neukirch, Levi P; Prestridge, Katherine; Rigg, Paolo; Saunders, Alexander; Schurman, Tamsen; Tainter, Amy; Trouw, Frans; Tupa, Dale; Tybo, Josh; Vogan-McNeil, Wendy; Wilde, Carl

    2017-01-01

    Relativistic, magnetically focused proton radiography was invented at Los Alamos National Laboratory using the 800 MeV LANSCE beam and is inherently well-suited to imaging dense objects, at areal densities >20 g cm -2 . However, if the unscattered portion of the transmitted beam is removed at the Fourier plane through inverse-collimation, this system becomes highly sensitive to very thin media, of areal densities <100 mg cm -2 . Here, this inverse-collimation scheme is described in detail and demonstrated by imaging Xe gas with a shockwave generated by an aluminum plate compressing the gas at Mach 8.8. With a 5-mrad inverse collimator, an areal density change of just 49 mg cm -2 across the shock front is discernible with a contrast-to-noise ratio of 3. Geant4 modeling of idealized and realistic proton transports can guide the design of inverse-collimators optimized for specific experimental conditions and show that this technique performs better for thin targets with reduced incident proton beam emittance. This work increases the range of areal densities to which the system is sensitive to span from ∼25 mg cm -2 to 100 g cm -2 , exceeding three orders of magnitude. This enables the simultaneous imaging of a dense system as well as thin jets and ejecta material that are otherwise difficult to characterize with high-energy proton radiography.

  14. Holographic memory using beam steering

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin (Inventor); Hanan, Jay C. (Inventor); Reyes, George F. (Inventor); Zhou, Hanying (Inventor)

    2006-01-01

    A method, apparatus, and system provide the ability for storing holograms at high speed. A single laser diode emits a collimated laser beam to both write to and read from a photorefractice crystal. One or more liquid crystal beam steering spatial light modulators (BSSLMs) or Micro-Electro-Mechanical Systems (MEMS) mirrors steer a reference beam, split from the collimated laser beam, at high speed to the photorefractive crystal.

  15. Radiation collimator and systems incorporating same

    DOEpatents

    Norman, Daren R [Idaho Falls, ID; Yoon, Woo Y [Idaho Falls, ID; Jones, James L [Idaho Falls, ID; Haskell, Kevin J [Idaho Falls, ID; Bennett, Brion D [Idaho Falls, ID; Tschaggeny, Charles W [Woods Cross, UT; Jones, Warren F [Idaho Falls, ID

    2011-09-13

    A collimator including a housing having disposed therein a shield element surrounding a converter core in which a photon beam is generated from electrons emanating from a linear accelerator. A beam channeler longitudinally adjacent the shield element has a beam aperture therethrough coaxially aligned with, and of the same diameter as, an exit bore of the converter core. A larger entry bore in the converter core is coaxial with, and longitudinally separated from, the exit bore thereof. Systems incorporating the collimator are also disclosed.

  16. Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging

    PubMed Central

    Van Audenhaege, Karen; Van Holen, Roel; Vandenberghe, Stefaan; Vanhove, Christian; Metzler, Scott D.; Moore, Stephen C.

    2015-01-01

    In single photon emission computed tomography, the choice of the collimator has a major impact on the sensitivity and resolution of the system. Traditional parallel-hole and fan-beam collimators used in clinical practice, for example, have a relatively poor sensitivity and subcentimeter spatial resolution, while in small-animal imaging, pinhole collimators are used to obtain submillimeter resolution and multiple pinholes are often combined to increase sensitivity. This paper reviews methods for production, sensitivity maximization, and task-based optimization of collimation for both clinical and preclinical imaging applications. New opportunities for improved collimation are now arising primarily because of (i) new collimator-production techniques and (ii) detectors with improved intrinsic spatial resolution that have recently become available. These new technologies are expected to impact the design of collimators in the future. The authors also discuss concepts like septal penetration, high-resolution applications, multiplexing, sampling completeness, and adaptive systems, and the authors conclude with an example of an optimization study for a parallel-hole, fan-beam, cone-beam, and multiple-pinhole collimator for different applications. PMID:26233207

  17. The realuminizing of the 7-meter-diameter solar simulator collimating mirror

    NASA Technical Reports Server (NTRS)

    Noller, E. W.

    1994-01-01

    This paper describes the modification of a three-electron-beam (EB) gun system for vacuum depositing a highly reflective aluminum coating on a 7.01-m (23-ft) -diam nickel-plated aluminum collimating mirror. The mirror is part of the JPL 7.62-m space simulator that was recently modernized with a new high vacuum pumping system, solar lamp power supplies, solar optic lens system, and refurbished collimating mirror. The 7.01-m 12,700-kg (14-ton) spherical collimating mirror was removed from this facility for replating with 381 micron (0.015 in.) of electroless nickel and polished to a specular finish for realuminizing. The space chamber served as the vacuum coating vessel for the realuminizing coating process. The mirror is the primary reflector for the solar simulation system and the aluminized reflective surface is its most critical performance element. The uniformity of thickness and high reflectivity of the coating in visible and near-ultraviolet (UV) light governs the accuracy of the beam for solar testing. The uniformity of the thin-film thickness also controls the durability of the mirror over time. The mirror was polished to a 64-percent reflectivity with a uniformity of 1.5 percent. The performance goal for the aluminizing was 89 percent with +/- 0.5-percent variation over the mirror.

  18. Study on Dynamic Alignment Technology of COIL Resonator

    NASA Astrophysics Data System (ADS)

    Xiong, M. D.; Zou, X. J.; Guo, J. H.; Jia, S. N.; Zhang2, Z. B.

    2006-10-01

    The performance of great power chemical oxygen-iodine laser (COIL) beam is decided mostly by resonator mirror maladjustment and environment vibration. To improve the performance of light beam, an auto-alignment device is used in COIL resonator, the device can keep COIL resonator collimating by adjusting the optical components of resonator. So the coupling model of COIL resonator is present. The multivariable self study fuzzy uncoupling arithmetic and six-dimensional micro drive technology are used to design a six-input-three-output uncoupling controller, resulting in the realization of the high precision dynamic alignment. The experiments indicate that the collimating range of this system is 8 mrad, precision is 5 urad and frequency response is 20Hz, which meet the demand of resonator alignment system.

  19. Carbon nanotube collimator fabrication and application

    DOEpatents

    Chow, Lee; Chai, Guangyu; Schenkel, Thomas

    2010-07-06

    Apparatus, methods, systems and devices for fabricating individual CNT collimators. Micron size fiber coated CNT samples are synthesized with chemical vapor deposition method and then the individual CNT collimators are fabricated with focused ion beam technique. Unfocused electron beams are successfully propagated through the CNT collimators. The CNT nano-collimators are used for applications including single ion implantation and in high-energy physics, and allow rapid, reliable testing of the transmission of CNT arrays for transport of molecules.

  20. Slit-Slat Collimator Equipped Gamma Camera for Whole-Mouse SPECT-CT Imaging

    NASA Astrophysics Data System (ADS)

    Cao, Liji; Peter, Jörg

    2012-06-01

    A slit-slat collimator is developed for a gamma camera intended for small-animal imaging (mice). The tungsten housing of a roof-shaped collimator forms a slit opening, and the slats are made of lead foils separated by sparse polyurethane material. Alignment of the collimator with the camera's pixelated crystal is performed by adjusting a micrometer screw while monitoring a Co-57 point source for maximum signal intensity. For SPECT, the collimator forms a cylindrical field-of-view enabling whole mouse imaging with transaxial magnification and constant on-axis sensitivity over the entire axial direction. As the gamma camera is part of a multimodal imaging system incorporating also x-ray CT, five parameters corresponding to the geometric displacements of the collimator as well as to the mechanical co-alignment between the gamma camera and the CT subsystem are estimated by means of bimodal calibration sources. To illustrate the performance of the slit-slat collimator and to compare its performance to a single pinhole collimator, a Derenzo phantom study is performed. Transaxial resolution along the entire long axis is comparable to a pinhole collimator of same pinhole diameter. Axial resolution of the slit-slat collimator is comparable to that of a parallel beam collimator. Additionally, data from an in-vivo mouse study are presented.

  1. TU-H-BRC-09: Validation of a Novel Therapeutic X-Ray Array Source and Collimation System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Trovati, S; King, GJ; Loo, BW

    2016-06-15

    Purpose: We have experimentally characterized and simulated the dosimetric properties and spatial fidelity of a novel X-ray array source and collimation system called SPHINX that has the potential to generate complex intensity modulated X-ray beams by varying the electron beam intensity only, and without any moving parts like in multi-leaf collimators. Methods: We investigated the spatial fidelity and the X-ray performances of a SPHINX prototype in tungsten, using a Cyber Knife and the experimental high-energy electron beam line at XTA at SLAC National Laboratory. Dose distributions were recorded with gafchromic films, placed at the distal end of SPHINX and atmore » several depths in a solid water phantom. The geometry of SPHINX and of the experimental set-ups was also modeled in Monte Carlo (MC) simulations with the FLUKA code, used to reproduce the experimental results and, after validation, to predict and optimize the performance and design of the SPHINX. Results: The results indicate significant particle leakage through the channels during a single-channel irradiation for high incident energies, followed by a rapid decrease for energies of clinical interest. When the collimator channels are used as target, the photon production increases, however at expense of the beam size that is also enlarged. The illumination of all channels simultaneously shows a fairly even transmission of the beam. Conclusion: With the measurements we have verified the MC models and the uniformity of beam transmission through SPHINX, and we have evaluated the importance of particle leakage through adjacent channels. These results can be used to optimize SPHINX design through the validated MC simulations. Funding: Weston Havens Foundation, Office of the Dean of Medical School and Office of the Provost (Stanford University). Loo, Maxim, Borchard, Tantawi are co-founders of TibaRay Inc. Loo and Tantawi are TibaRay Inc. board members. Loo and Maxim received grants from Varian Medical Systems and RaySearch Laboratory.« less

  2. Holographic memory using beam steering

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin (Inventor); Hanan, Jay C. (Inventor); Reyes, George F. (Inventor); Zhou, Hanying (Inventor)

    2007-01-01

    A method, apparatus, and system provide the ability for storing holograms at high speed. A single laser diode emits a collimated laser beam to both write to and read from a photorefractice crystal. One or more liquid crystal beam steering spatial light modulators (BSSLMs) steer a reference beam, split from the collimated laser beam, at high speed to the photorefractive crystal.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mihailescu, Lucian

    This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.

  4. High contrast laser beam collimation testing using two proximately placed holographic optical elements

    NASA Astrophysics Data System (ADS)

    Rajkumar; Dubey, Rajiv; Debnath, Sanjit K.; Chhachhia, D. P.

    2018-05-01

    Accuracy in laser beam collimation is very important in systems used for precision measurements. The present work reports a technique for collimation testing of laser beams using two proximately placed holographic optical elements (HOEs). The required HOEs are designed and fabricated such that upon illumination with the test beam, they release two laterally sheared wavefronts, at desired angles from the directly transmitted beam, that superimpose each other to generate straight interference fringes. Deviation from the collimation of the test beam results in orientation of these otherwise horizontal fringes. The novelty of this setup comes from the fact that HOEs are lightweight, as well as easy to fabricate as compared to conventional wedge plates used for collimation testing, and generate high contrast fringes compared to other interferometry, holography, Talbot and Moiré based techniques in a compact manner. The proposed technique is experimentally validated by measuring the orientation of fringes by an angle of 16.4° when a collimating lens of focal length 200 mm is defocused by 600 μm. The accuracy in the setting of this collimation position is obtained to be 10 μm.

  5. Characterization of the Shielded Neutron Source at Triangle Universities Nuclear Laboratory

    NASA Astrophysics Data System (ADS)

    Hobson, Chad; Finch, Sean; Howell, Calvin; Malone, Ron; Tornow, Wernew

    2016-09-01

    In 2015, Triangle Universities Nuclear Laboratory rebuilt its shielded neutron source (SNS) with the goal of improving neutron beam collimation and reducing neutron and gamma-ray backgrounds. Neutrons are produced via the 2H(d,n)3He reaction and then collimated by heavy shielding to form a beam. The SNS has the ability to produce both a rectangular and circular neutron beam through use of two collimators with different beam apertures. Our work characterized both the neutron beam profiles as well as the neutron and gamma-ray backgrounds at various locations around the SNS. This characterization was performed to provide researchers who use the SNS with beam parameters necessary to plan and conduct an experiment. Vertical and horizontal beam profiles were measured at two different distances from the neutron production cell by scanning a small plastic scintillator across the face of the beam at various energies for each collimator. Background neutron and gamma-ray intensities were measured using time-of-flight techniques at 10 MeV and 16 MeV with the rectangular collimator. We present results on the position and size of neutron beam as well as on the structure and magnitude of the backgrounds.

  6. Mini-beam collimator applications at the Advanced Photon Source

    NASA Astrophysics Data System (ADS)

    Xu, Shenglan; Keefe, Lisa J.; Mulichak, Anne; Yan, Lifen; Alp, Ercan E.; Zhao, Jiyong; Fischetti, Robert F.

    2011-09-01

    In 2007, the General Medicine and Cancer Institutes Collaborative Access Team (GM/CA CAT, Sector 23, Advanced Photon Source) began providing mini-beam collimators to its users. These collimators contained individual, 5- or 10-μm pinholes and were rapidly exchangeable, thereby allowing users to tailor the beam size to their experimental needs. The use of these collimators provided a reduction in background noise, and thus improved the signal-to-noise ratio [1,2]. Recent improvements in the collimator design include construction of the device from a monolithic piece of molybdenum with multiple pinholes mounted inside [3]. This allows users to select from various size options from within the beamline control software without the realignment that was previously necessary. In addition, a new, 20-μm pinhole has been added to create a "quad-collimator", resulting in greater flexibility for the users. The mini-beam collimator is now available at multiple crystallographic beamlines and also is a part of the first Mössbauer Microscopic system at sector 3-ID.

  7. EPICS Controlled Collimator for Controlling Beam Sizes in HIPPO

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Napolitano, Arthur Soriano; Vogel, Sven C.

    2017-08-03

    Controlling the beam spot size and shape in a diffraction experiment determines the probed sample volume. The HIPPO - High-Pressure-Preferred Orientation– neutron time-offlight diffractometer is located at the Lujan Neutron Scattering Center in Los Alamos National Laboratories. HIPPO characterizes microstructural parameters, such as phase composition, strains, grain size, or texture, of bulk (cm-sized) samples. In the current setup, the beam spot has a 10 mm diameter. Using a collimator, consisting of two pairs of neutron absorbing boron-nitride slabs, horizontal and vertical dimensions of a rectangular beam spot can be defined. Using the HIPPO robotic sample changer for sample motion, themore » collimator would enable scanning of e.g. cylindrical samples along the cylinder axis by probing slices of such samples. The project presented here describes implementation of such a collimator, in particular the motion control software. We utilized the EPICS (Experimental Physics Interface and Control System) software interface to integrate the collimator control into the HIPPO instrument control system. Using EPICS, commands are sent to commercial stepper motors that move the beam windows.« less

  8. Design a freeform microlens array module for any arbitrary-shape collimated beam shaping and color mixing

    NASA Astrophysics Data System (ADS)

    Chen, Enguo; Wu, Rengmao; Guo, Tailiang

    2014-06-01

    Collimated beam shaping with freeform surface usually employs a predefined mapping to tailor one or multiple freeform surfaces. Limitation on those designs is that the source, the freeform optics and the target are in fixed one-to-one correspondence with each other. To overcome this drawback, this paper presents a kind of freeform microlens array module integrated with an ultra-thin freeform microlens array and a condenser lens to reshape any arbitrary-shape collimated beam into a prescribed uniform rectangular illumination and achieve color mixing. The design theory is explicitly given, and some key issues are addressed. Several different application examples are given, and the target is obtained with high uniformity and energy efficiency. This freeform microlens array module, which shows better flexibility and practicality than the regular designs, can be used not only to reshape any arbitrary-shape collimated beam (or a collimated beam integrated with several sub-collimated beams), but also most importantly to achieve color mixing. With excellent optical performance and ultra-compact volume, this optical module together with the design theory can be further introduced into other applications and will have a huge market potential in the near future.

  9. Beam Loss Simulation and Collimator System Configurations for the Advanced Photon Source Upgrade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiao, A.; Borland, M.

    The proposed multi-bend achromat lattice for the Advanced Photon Source upgrade (APS-U) has a design emittance of less than 70 pm. The Touschek loss rate is high: compared with the current APS ring, which has an average beam lifetime ~ 10 h, the simulated beam lifetime for APS-U is only ~2 h when operated in the high flux mode (I=200 mA in 48 bunches). An additional consequence of the short lifetime is that injection must be more frequent, which provides another potential source of particle loss. In order to provide information for the radiation shielding system evaluation and to avoidmore » particle loss in sensitive locations around the ring (for example, insertion device straight sections), simulations of the detailed beam loss distribution have been performed. Several possible collimation configurations have been simulated and compared.« less

  10. Anomaly Detection for Beam Loss Maps in the Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Valentino, Gianluca; Bruce, Roderik; Redaelli, Stefano; Rossi, Roberto; Theodoropoulos, Panagiotis; Jaster-Merz, Sonja

    2017-07-01

    In the LHC, beam loss maps are used to validate collimator settings for cleaning and machine protection. This is done by monitoring the loss distribution in the ring during infrequent controlled loss map campaigns, as well as in standard operation. Due to the complexity of the system, consisting of more than 50 collimators per beam, it is difficult to identify small changes in the collimation hierarchy, which may be due to setting errors or beam orbit drifts with such methods. A technique based on Principal Component Analysis and Local Outlier Factor is presented to detect anomalies in the loss maps and therefore provide an automatic check of the collimation hierarchy.

  11. Modeling of beam customization devices in the pencil-beam splitting algorithm for heavy charged particle radiotherapy.

    PubMed

    Kanematsu, Nobuyuki

    2011-03-07

    A broad-beam-delivery system for radiotherapy with protons or ions often employs multiple collimators and a range-compensating filter, which offer complex and potentially useful beam customization. It is however difficult for conventional pencil-beam algorithms to deal with fine structures of these devices due to beam-size growth during transport. This study aims to avoid the difficulty with a novel computational model. The pencil beams are initially defined at the range-compensating filter with angular-acceptance correction for upstream collimation followed by stopping and scattering. They are individually transported with possible splitting near the aperture edge of a downstream collimator to form a sharp field edge. The dose distribution for a carbon-ion beam was calculated and compared with existing experimental data. The penumbra sizes of various collimator edges agreed between them to a submillimeter level. This beam-customization model will be used in the greater framework of the pencil-beam splitting algorithm for accurate and efficient patient dose calculation.

  12. Numerical Calculations of Short-Range Wakefields of Collimators

    NASA Astrophysics Data System (ADS)

    Ng, C. K.

    2001-12-01

    The performance of future linear colliders are limited by the effect of short-range collimator wakefields on the beam. The beam quality is sensitive to the positioning of collimators at the end of the linac. The determination of collimator wakefields has been difficult, largely because of the scarcity of measurement data, and of the limitation of applicability of analytical results to realistic structures. In this paper, numerical methods using codes such as MAFIA are used to determine a series of tapered collimators with rectangular apertures that have been built for studies at SLAC (Stanford Linear Accelerator Center). We will study the dependences of the wakefield on the collimator taper angle, the collimator gap as well as the bunch length. Calculations are also compared with measurements.

  13. Neutron beam optimization based on a 7Li(p,n)7Be reaction for treatment of deep-seated brain tumors by BNCT

    NASA Astrophysics Data System (ADS)

    Zahra Ahmadi, Ganjeh; S. Farhad, Masoudi

    2014-10-01

    Neutron beam optimization for accelerator-based Boron Neutron Capture Therapy (BNCT) is investigated using a 7Li(p,n)7Be reaction. Design and optimization have been carried out for the target, cooling system, moderator, filter, reflector, and collimator to achieve a high flux of epithermal neutron and satisfy the IAEA criteria. Also, the performance of the designed beam in tissue is assessed by using a simulated Snyder head phantom. The results show that the optimization of the collimator and reflector is critical to finding the best neutron beam based on the 7Li(p,n)7Be reaction. Our designed beam has 2.49×109n/cm2s epithermal neutron flux and is suitable for BNCT of deep-seated brain tumors.

  14. Reduction of the unnecessary dose from the over-range area with a spiral dynamic z-collimator: comparison of beam pitch and detector coverage with 128-detector row CT.

    PubMed

    Shirasaka, Takashi; Funama, Yoshinori; Hayashi, Mutsukazu; Awamoto, Shinichi; Kondo, Masatoshi; Nakamura, Yasuhiko; Hatakenaka, Masamitsu; Honda, Hiroshi

    2012-01-01

    Our purpose in this study was to assess the radiation dose reduction and the actual exposed scan length of over-range areas using a spiral dynamic z-collimator at different beam pitches and detector coverage. Using glass rod dosimeters, we measured the unilateral over-range scan dose between the beginning of the planned scan range and the beginning of the actual exposed scan range. Scanning was performed at detector coverage of 80.0 and 40.0 mm, with and without the spiral dynamic z-collimator. The dose-saving ratio was calculated as the ratio of the unnecessary over-range dose, with and without the spiral dynamic z-collimator. In 80.0 mm detector coverage without the spiral dynamic z-collimator, the actual exposed scan length for the over-range area was 108, 120, and 126 mm, corresponding to a beam pitch of 0.60, 0.80, and 0.99, respectively. With the spiral dynamic z-collimator, the actual exposed scan length for the over-range area was 48, 66, and 84 mm with a beam pitch of 0.60, 0.80, and 0.99, respectively. The dose-saving ratios with and without the spiral dynamic z-collimator for a beam pitch of 0.60, 0.80, and 0.99 were 35.07, 24.76, and 13.51%, respectively. With 40.0 mm detector coverage, the dose-saving ratios with and without the spiral dynamic z-collimator had the highest value of 27.23% with a low beam pitch of 0.60. The spiral dynamic z-collimator is important for a reduction in the unnecessary over-range dose and makes it possible to reduce the unnecessary dose by means of a lower beam pitch.

  15. WE-AB-BRB-10: Filmless QA of CyberKnife MLC-Collimated and Iris-Collimated Fields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gersh, J; Spectrum Medical Physics, LLC, Greenville, SC

    Purpose: Current methods of CK field shape QA is based on the use of radiochromic film. Though accurate results can be attained, these methods are prone to error, time consuming, and expensive. The techniques described herein perform similar QA using the FOIL Detector (Field, Output, and Image Localization). A key feature of this in-house QA solution, and central to this study, is an aSi flat-panel detector which provides the user with the means to perform accurate, immediate, and quantitative field analysis. Methods: The FOIL detector is automatically aligned in the CK beam using fiducial markers implanted within the detector case.more » Once the system is aligned, a treatment plan is delivered which irradiates the flat-panel imager using the field being tested. The current study tests each of the clinically-used fields shaped using the Iris variable-aperture collimation system using a plan which takes 6 minutes to deliver. The user is immediately provided with field diameter and beam profile, as well as a comparison to baseline values. Additionally, the detector is used to acquire and analyze leaf positions of the InCise multi-leaf collimation system. Results: Using a 6-minute plan consisting of 11 beams of 25MU-per-beam, the FOIL detector provided the user with a quantitative analysis of all clinically-used field shapes. The FOIL detector was also able to clearly resolve field edge junctions in a picket fence test, including slight over-travel of individual leaves as well as inter-leaf leakage. Conclusion: The FOIL system provided comparable field diameter and profile data when compared to methods using film; providing results much faster and with 5% of the MU used for film. When used with the MLC system, the FOIL detector provided the means for immediate quantification of the performance of the system through analysis of leaf positions in a picket fence test field. Author is the President/Owner of Spectrum Medical Physics, LLC, a company which maintains contracts with Siemens Healthcare and Standard Imaging, Inc.« less

  16. High resolution collimator system for X-ray detector

    DOEpatents

    Eberhard, Jeffrey W.; Cain, Dallas E.

    1987-01-01

    High resolution in an X-ray computerized tomography (CT) inspection system is achieved by using a collimator/detector combination to limit the beam width of the X-ray beam incident on a detector element to the desired resolution width. In a detector such as a high pressure Xenon detector array, a narrow tapered collimator is provided above a wide detector element. The collimator slits have any desired width, as small as a few mils at the top, the slit width is easily controlled, and they are fabricated on standard machines. The slit length determines the slice thickness of the CT image.

  17. Measurement system with high accuracy for laser beam quality.

    PubMed

    Ke, Yi; Zeng, Ciling; Xie, Peiyuan; Jiang, Qingshan; Liang, Ke; Yang, Zhenyu; Zhao, Ming

    2015-05-20

    Presently, most of the laser beam quality measurement system collimates the optical path manually with low efficiency and low repeatability. To solve these problems, this paper proposed a new collimated method to improve the reliability and accuracy of the measurement results. The system accuracy controlled the position of the mirror to change laser beam propagation direction, which can realize the beam perpendicularly incident to the photosurface of camera. The experiment results show that the proposed system has good repeatability and the measuring deviation of M2 factor is less than 0.6%.

  18. Wavefront sensing and adaptive control in phased array of fiber collimators

    NASA Astrophysics Data System (ADS)

    Lachinova, Svetlana L.; Vorontsov, Mikhail A.

    2011-03-01

    A new wavefront control approach for mitigation of atmospheric turbulence-induced wavefront phase aberrations in coherent fiber-array-based laser beam projection systems is introduced and analyzed. This approach is based on integration of wavefront sensing capabilities directly into the fiber-array transmitter aperture. In the coherent fiber array considered, we assume that each fiber collimator (subaperture) of the array is capable of precompensation of local (onsubaperture) wavefront phase tip and tilt aberrations using controllable rapid displacement of the tip of the delivery fiber at the collimating lens focal plane. In the technique proposed, this tip and tilt phase aberration control is based on maximization of the optical power received through the same fiber collimator using the stochastic parallel gradient descent (SPGD) technique. The coordinates of the fiber tip after the local tip and tilt aberrations are mitigated correspond to the coordinates of the focal-spot centroid of the optical wave backscattered off the target. Similar to a conventional Shack-Hartmann wavefront sensor, phase function over the entire fiber-array aperture can then be retrieved using the coordinates obtained. The piston phases that are required for coherent combining (phase locking) of the outgoing beams at the target plane can be further calculated from the reconstructed wavefront phase. Results of analysis and numerical simulations are presented. Performance of adaptive precompensation of phase aberrations in this laser beam projection system type is compared for various system configurations characterized by the number of fiber collimators and atmospheric turbulence conditions. The wavefront control concept presented can be effectively applied for long-range laser beam projection scenarios for which the time delay related with the double-pass laser beam propagation to the target and back is compared or even exceeds the characteristic time of the atmospheric turbulence change - scenarios when conventional target-in-the-loop phase-locking techniques fail.

  19. Thermal analysis and cooling structure design of the primary collimator in CSNS/RCS

    NASA Astrophysics Data System (ADS)

    Zou, Yi-Qing; Wang, Na; Kang, Ling; Qu, Hua-Min; He, Zhe-Xi; Yu, Jie-Bing

    2013-05-01

    The rapid cycling synchrotron (RCS) of the China Spallation Neutron Source (CSNS) is a high intensity proton ring with beam power of 100 kW. In order to control the residual activation to meet the requirements of hands-on maintenance, a two-stage collimation system has been designed for the RCS. The collimation system consists of one primary collimator made of thin metal to scatter the beam and four secondary collimators as absorbers. Thermal analysis is an important aspect in evaluating the reliability of the collimation system. The calculation of the temperature distribution and thermal stress of the primary collimator with different materials is carried out by using ANSYS code. In order to control the temperature rise and thermal stress of the primary collimator to a reasonable level, an air cooling structure is intended to be used. The mechanical design of the cooling structure is presented, and the cooling efficiency with different chin numbers and wind velocity is also analyzed. Finally, the fatigue lifetime of the collimator under thermal shocks is estimated.

  20. Inverse-collimated proton radiography for imaging thin materials

    DOE PAGES

    Freeman, Matthew S.; Allison, Jason; Andrews, Malcolm; ...

    2017-01-01

    Relativistic, magnetically-focused proton radiography was invented at Los Alamos National Laboratory using the 800 MeV LANSCE beam, and is inherently well-suited to imaging dense objects, at areal densities >20 g cm -2. However, if the unscattered portion of the transmitted beam is removed at the Fourier plane through inverse-collimation, this system becomes highly sensitive to very thin media, of areal densities <100 mg cm -2. Here, this inversecollimation scheme is described in detail and demonstrated by imaging Xe gas with a shockwave generated by an aluminum plate compressing the gas at Mach 8.8. With a 5-mrad inverse collimator, an arealmore » density change of just 49 mg cm-2 across the shock front is discernible with a contrast-to-noise ratio of 3. Geant4 modeling of idealized and realistic proton transports can guide the design of inverse-collimators optimized for specific experimental conditions and show that this technique performs better for thin targets with reduced incident proton beam emittance. This work increases the range of areal densities to which the system is sensitive to span from ~25 mg cm -2 to 100 g cm -2, exceeding three orders of magnitude. This enables the simultaneous imaging of a dense system, as well as thin jets and ejecta material that are otherwise difficult to characterize with high-energy proton radiography.« less

  1. Modeling of beam-induced damage of the LHC tertiary collimators

    NASA Astrophysics Data System (ADS)

    Quaranta, E.; Bertarelli, A.; Bruce, R.; Carra, F.; Cerutti, F.; Lechner, A.; Redaelli, S.; Skordis, E.; Gradassi, P.

    2017-09-01

    Modern hadron machines with high beam intensity may suffer from material damage in the case of large beam losses and even beam-intercepting devices, such as collimators, can be harmed. A systematic method to evaluate thresholds of damage owing to the impact of high energy particles is therefore crucial for safe operation and for predicting possible limitations in the overall machine performance. For this, a three-step simulation approach is presented, based on tracking simulations followed by calculations of energy deposited in the impacted material and hydrodynamic simulations to predict the thermomechanical effect of the impact. This approach is applied to metallic collimators at the CERN Large Hadron Collider (LHC), which in standard operation intercept halo protons, but risk to be damaged in the case of extraction kicker malfunction. In particular, tertiary collimators protect the aperture bottlenecks, their settings constrain the reach in β* and hence the achievable luminosity at the LHC experiments. Our calculated damage levels provide a very important input on how close to the beam these collimators can be operated without risk of damage. The results of this approach have been used already to push further the performance of the present machine. The risk of damage is even higher in the upgraded high-luminosity LHC with higher beam intensity, for which we quantify existing margins before equipment damage for the proposed baseline settings.

  2. Alignment reference device

    DOEpatents

    Patton, Gail Y.; Torgerson, Darrel D.

    1987-01-01

    An alignment reference device provides a collimated laser beam that minimizes angular deviations therein. A laser beam source outputs the beam into a single mode optical fiber. The output end of the optical fiber acts as a source of radiant energy and is positioned at the focal point of a lens system where the focal point is positioned within the lens. The output beam reflects off a mirror back to the lens that produces a collimated beam.

  3. Experimental Comparison of Knife-Edge and Multi-Parallel Slit Collimators for Prompt Gamma Imaging of Proton Pencil Beams.

    PubMed

    Smeets, Julien; Roellinghoff, Frauke; Janssens, Guillaume; Perali, Irene; Celani, Andrea; Fiorini, Carlo; Freud, Nicolas; Testa, Etienne; Prieels, Damien

    2016-01-01

    More and more camera concepts are being investigated to try and seize the opportunity of instantaneous range verification of proton therapy treatments offered by prompt gammas emitted along the proton tracks. Focusing on one-dimensional imaging with a passive collimator, the present study experimentally compared in combination with the first, clinically compatible, dedicated camera device the performances of instances of the two main options: a knife-edge slit (KES) and a multi-parallel slit (MPS) design. These two options were experimentally assessed in this specific context as they were previously demonstrated through analytical and numerical studies to allow similar performances in terms of Bragg peak retrieval precision and spatial resolution in a general context. Both collimators were prototyped according to the conclusions of Monte Carlo optimization studies under constraints of equal weight (40 mm tungsten alloy equivalent thickness) and of the specificities of the camera device under consideration (in particular 4 mm segmentation along beam axis and no time-of-flight discrimination, both of which less favorable to the MPS performance than to the KES one). Acquisitions of proton pencil beams of 100, 160, and 230 MeV in a PMMA target revealed that, in order to reach a given level of statistical precision on Bragg peak depth retrieval, the KES collimator requires only half the dose the present MPS collimator needs, making the KES collimator a preferred option for a compact camera device aimed at imaging only the Bragg peak position. On the other hand, the present MPS collimator proves more effective at retrieving the entrance of the beam in the target in the context of an extended camera device aimed at imaging the whole proton track within the patient.

  4. Poster — Thur Eve — 19: Performance assessment of a 160-leaf beam collimation system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ali, E. S. M.; La Russa, D. J.; Vandervoort, E.

    2014-08-15

    In this study, the performance of the new beam collimation system with 160 leaves, each with a 5 mm leaf width projected at isocenter, is evaluated in terms of positional accuracy and plan/delivery quality. Positional accuracy was evaluated using a set of static and dynamic MLC/jaw delivery patterns at different gantry angles, dose rates, and MLC/jaw speeds. The impact on IMRT plan quality was assessed by comparing against a previous generation collimation system using the same optimization parameters, while delivery quality was quantified using a combination of patient-specific QA measurements with ion chambers, film, and a bi-planar diode array. Positionalmore » accuracy for four separate units was comparable. The field size accuracy, junction width, and total displacement over 16 cm leaf travel are 0.3 ± 0.2 mm, 0.4 ± 0.3 mm, and 0.5 ± 0.2 mm, respectively. The typical leaf minor offset is 0.05 ± 0.04 mm, and MLC hysteresis effects are 0.2 ± 0.1 mm over 16 cm travel. The dynamic output is linear with MU and MLC/jaw speed, and is within 0.7 ± 0.3 % of the planning system value. Plan quality is significantly improved both in terms of target coverage and OAR sparing due, in part, to the larger allowable MLC and jaw speeds. γ-index pass rates for the patient-specific QA measurements exceeded 97% using criteria of 2%/2 mm. In conclusion, the performance of the Agility system is consistent among four separate installations, and is superior to its previous generations of collimation systems.« less

  5. Compact laser transmitter delivering a long-range infrared beam aligned with a monitoring visible beam.

    PubMed

    Lee, Hong-Shik; Kim, Haeng-In; Lee, Sang-Shin

    2012-06-10

    A compact laser transmitter, which takes advantage of an optical subassembly module, was proposed and demonstrated, providing precisely aligned collinear IR and visible beams. The collimated IR beam acts as a long-range projectile for simulated combat, carrying an optical pulsed signal, whereas the visible beam plays the role of tracking the IR beam. The proposed laser transmitter utilizes IR (λ(1)=905 nm) and visible (λ(2)=660 nm) light sources, a fiber-optic collimator, and a beam combiner, which includes a wavelength division multiplexing (WDM) filter in conjunction with optical fiber. The device was built via the laser welding technique and then evaluated by investigating the characteristics of the generated light beams. The IR collimated beam produced had a Gaussian profile and a divergence angle of ~1.3 mrad, and the visible monitoring beam was appropriately collimated to be readily discernible in the vicinity of the transmitter. The two beams were highly aligned within an angle of 0.004 deg as anticipated. Finally, we performed a practical outdoor field test to assess the IR beam with the help of a receiver. An effective trajectory was observed ranging up to 660 m with an overall detectable beam width of ~60 cm.

  6. Analysis and experimental demonstration of conformal adaptive phase-locked fiber array for laser communications and beam projection applications

    NASA Astrophysics Data System (ADS)

    Liu, Ling

    The primary goal of this research is the analysis, development, and experimental demonstration of an adaptive phase-locked fiber array system for free-space optical communications and laser beam projection applications. To our knowledge, the developed adaptive phase-locked system composed of three fiber collimators (subapertures) with tip-tilt wavefront phase control at each subaperture represents the first reported fiber array system that implements both phase-locking control and adaptive wavefront tip-tilt control capabilities. This research has also resulted in the following innovations: (a) The first experimental demonstration of a phase-locked fiber array with tip-tilt wave-front aberration compensation at each fiber collimator; (b) Development and demonstration of the fastest currently reported stochastic parallel gradient descent (SPGD) system capable of operation at 180,000 iterations per second; (c) The first experimental demonstration of a laser communication link based on a phase-locked fiber array; (d) The first successful experimental demonstration of turbulence and jitter-induced phase distortion compensation in a phase-locked fiber array optical system; (e) The first demonstration of laser beam projection onto an extended target with a randomly rough surface using a conformal adaptive fiber array system. Fiber array optical systems, the subject of this study, can overcome some of the draw-backs of conventional monolithic large-aperture transmitter/receiver optical systems that are usually heavy, bulky, and expensive. The primary experimental challenges in the development of the adaptive phased-locked fiber-array included precise (<5 microrad) alignment of the fiber collimators and development of fast (100kHz-class) phase-locking and wavefront tip-tilt control systems. The precise alignment of the fiber collimator array is achieved through a specially developed initial coarse alignment tool based on high precision piezoelectric picomotors and a dynamic fine alignment mechanism implemented with specially designed and manufactured piezoelectric fiber positioners. Phase-locking of the fiber collimators is performed by controlling the phases of the output beams (beamlets) using integrated polarization-maintaining (PM) fiber-coupled LiNbO3 phase shifters. The developed phase-locking controllers are based on either the SPGD algorithm or the multi-dithering technique. Subaperture wavefront phase tip-tilt control is realized using piezoelectric fiber positioners that are controlled using a computer-based SPGD controller. Both coherent (phase-locked) and incoherent beam combining in the fiber array system are analyzed theoretically and experimentally. Two special fiber-based beam-combining testbeds have been built to demonstrate the technical feasibility of phase-locking compensation prior to free-space operation. In addition, the reciprocity of counter-propagating beams in a phase-locked fiber array system has been investigated. Coherent beam combining in a phase-locking system with wavefront phase tip-tilt compensation at each subaperture is successfully demonstrated when laboratory-simulated turbulence and wavefront jitters are present in the propagation path of the beamlets. In addition, coherent beam combining with a non-cooperative extended target in the control loop is successfully demonstrated.

  7. High energy beam impact tests on a LHC tertiary collimator at the CERN high-radiation to materials facility

    NASA Astrophysics Data System (ADS)

    Cauchi, Marija; Aberle, O.; Assmann, R. W.; Bertarelli, A.; Carra, F.; Cornelis, K.; Dallocchio, A.; Deboy, D.; Lari, L.; Redaelli, S.; Rossi, A.; Salvachua, B.; Mollicone, P.; Sammut, N.

    2014-02-01

    The correct functioning of a collimation system is crucial to safely operate highly energetic particle accelerators, such as the Large Hadron Collider (LHC). The requirements to handle high intensity beams can be demanding. In this respect, investigating the consequences of LHC particle beams hitting tertiary collimators (TCTs) in the experimental regions is a fundamental issue for machine protection. An experimental test was designed to investigate the robustness and effects of beam accidents on a fully assembled collimator, based on accident scenarios in the LHC. This experiment, carried out at the CERN High-Radiation to Materials (HiRadMat) facility, involved 440 GeV proton beam impacts of different intensities on the jaws of a horizontal TCT. This paper presents the experimental setup and the preliminary results obtained, together with some first outcomes from visual inspection and a comparison of such results with numerical simulations.

  8. Measurement of bow tie profiles in CT scanners using a real-time dosimeter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Whiting, Bruce R., E-mail: whitingbrucer@gmail.com; Evans, Joshua D.; Williamson, Jeffrey F.

    2014-10-15

    Purpose: Several areas of computed tomography (CT) research require knowledge about the intensity profile of the x-ray fan beam that is introduced by a bow tie filter. This information is considered proprietary by CT manufacturers, so noninvasive measurement methods are required. One method using real-time dosimeters has been proposed in the literature. A commercially available dosimeter was used to apply that method, and analysis techniques were developed to extract fan beam profiles from measurements. Methods: A real-time ion chamber was placed near the periphery of an empty CT gantry and the dose rate versus time waveform was recorded as themore » x-ray source rotated about the isocenter. In contrast to previously proposed analysis methods that assumed a pointlike detector, the finite-size ion chamber received varying amounts of coverage by the collimated x-ray beam during rotation, precluding a simple relationship between the source intensity as a function of fan beam angle and measured intensity. A two-parameter model for measurement intensity was developed that included both effective collimation width and source-to-detector distance, which then was iteratively solved to minimize the error between duplicate measurements at corresponding fan beam angles, allowing determination of the fan beam profile from measured dose-rate waveforms. Measurements were performed on five different scanner systems while varying parameters such as collimation, kVp, and bow tie filters. On one system, direct measurements of the bow tie profile were collected for comparison with the real-time dosimeter technique. Results: The data analysis method for a finite-size detector was found to produce a fan beam profile estimate with a relative error between duplicate measurement intensities of <5%. It was robust over a wide range of collimation widths (e.g., 1–40 mm), producing fan beam profiles that agreed with a relative error of 1%–5%. Comparison with a direct measurement technique on one system produced agreement with a relative error of 2%–6%. Fan beam profiles were found to differ for different filter types on a given system and between different vendors. Conclusions: A commercially available real-time dosimeter probe was found to be a convenient and accurate instrument for measuring fan beam profiles. An analysis method was developed that could handle a wide range of collimation widths by explicitly considering the finite width of the ion chamber. Relative errors in the profiles were found to be less than 5%. Measurements of five different clinical scanners demonstrate the variation in bow tie designs, indicating that generic bow tie models will not be adequate for CT system research.« less

  9. Dual laser optical system and method for studying fluid flow

    NASA Technical Reports Server (NTRS)

    Owen, R. B.; Witherow, W. K. (Inventor)

    1983-01-01

    A dual laser optical system and method is disclosed for visualization of phenomena in transport substances which induce refractive index gradients such as fluid flow and pressure and temperature gradients in fluids and gases. Two images representing mutually perpendicular components of refractive index gradients may be viewed simultaneously on screen. Two lasers having wave lengths in the visible range but separated by about 1000 angstroms are utilized to provide beams which are collimated into a beam containing components of the different wave lengths. The collimated beam is passed through a test volume of the transparent substance. The collimated beam is then separated into components of the different wave lengths and focused onto a pair of knife edges arranged mutually perpendicular to produce and project images onto the screen.

  10. FLUKA Monte Carlo simulations and benchmark measurements for the LHC beam loss monitors

    NASA Astrophysics Data System (ADS)

    Sarchiapone, L.; Brugger, M.; Dehning, B.; Kramer, D.; Stockner, M.; Vlachoudis, V.

    2007-10-01

    One of the crucial elements in terms of machine protection for CERN's Large Hadron Collider (LHC) is its beam loss monitoring (BLM) system. On-line loss measurements must prevent the superconducting magnets from quenching and protect the machine components from damages due to unforeseen critical beam losses. In order to ensure the BLM's design quality, in the final design phase of the LHC detailed FLUKA Monte Carlo simulations were performed for the betatron collimation insertion. In addition, benchmark measurements were carried out with LHC type BLMs installed at the CERN-EU high-energy Reference Field facility (CERF). This paper presents results of FLUKA calculations performed for BLMs installed in the collimation region, compares the results of the CERF measurement with FLUKA simulations and evaluates related uncertainties. This, together with the fact that the CERF source spectra at the respective BLM locations are comparable with those at the LHC, allows assessing the sensitivity of the performed LHC design studies.

  11. Evaluating Red Reflex and Surgeon Preference Between Nearly-Collimated and Focused Beam Microscope Illumination Systems.

    PubMed

    Cionni, Robert J; Pei, Ron; Dimalanta, Ramon; Lubeck, David

    2015-08-01

    To evaluate the intensity and stability of the red reflex produced by ophthalmic surgical microscopes with nearly-collimated versus focused illumination systems and to assess surgeon preference in a simulated surgical setting. This two-part evaluation consisted of postproduction surgical video analysis of red reflex intensity and a microscope use and preference survey completed by 13 experienced cataract surgeons. Survey responses were based on bench testing and experience in a simulated surgical setting. A microscope with nearly-collimated beam illumination and two focused beam microscopes were assessed. Red reflex intensity and stability were greater with the nearly-collimated microscope illumination system. In the bench testing survey, surgeons reported that the red reflex was maintained over significantly greater distances away from pupillary center, and depth of focus was numerically greater with nearly-collimated illumination relative to focused illumination. Most participating surgeons (≥64%) reported a preference for the microscope with nearly-collimated illumination with regard to red reflex stability, depth of focus, visualization, surgical working distance, and perceived patient comfort. The microscope with nearly-collimated illumination produced a more intense and significantly more stable red reflex and was preferred overall by more surgeons. This is the first report of an attempt to quantify red reflex intensity and stability and to evaluate surgically-relevant parameters between microscope systems. The data and methods presented here may provide a basis for future studies attempting to quantify differences between surgical microscopes that may affect surgeon preference and microscope use in ophthalmic surgery.

  12. Demonstrating H- beam focusing using an elliptical einzel lens

    NASA Astrophysics Data System (ADS)

    Lawrie, S. R.; Faircloth, D. C.; Letchford, A. P.; Whitehead, M. O.; Wood, T.

    2017-08-01

    H- ion source research is being performed at the ISIS spallation neutron and muon facility on a dedicated Vessel for Extraction and Source Plasma Analyses (VESPA). The ion extraction and optics system presently being used on ISIS is centered on a combined-function sector dipole magnet. This traps cesium vapor escaping the ion source; mass-separates co-extracted electrons and stripped neutrals, and weak-focusses the highly asymmetric slit-shaped ion beam. Unfortunately the added drift length through the magnet under strong space-charge forces means up to 50% of the beam is collimated on the magnet. The VESPA has shown that the ISIS ion source actually produces 80 mA of beam current at standard settings, but because of magnet collimation only 55 mA is injected into the solenoid Low Energy Beam Transport (LEBT). A new purely electrostatic post-extraction system incorporating an einzel lens with an elliptical aperture is currently under test. This allows much greater flexibility of perveance and phase space matching for injection into the LEBT and Radio Frequency Quadrupole (RFQ). This paper discusses high voltage breakdown mitigation strategies and presents the first results of the novel elliptical transport system. So far, 70 mA of beam has been transported through the new system with a normalized transverse RMS emittance of 0.2 π mm mrad.

  13. SU-G-IeP4-04: DD-Neutron Source Collimation for Neutron Stimulated Emission Computed Tomography: A Monte Carlo Simulation Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fong, G; Kapadia, A

    Purpose: To optimize collimation and shielding for a deuterium-deuterium (DD) neutron generator for an inexpensive and compact clinical neutron imaging system. The envisioned application is cancer diagnosis through Neutron Stimulated Emission Computed Tomography (NSECT). Methods: Collimator designs were tested with an isotropic 2.5 MeV neutron source through GEANT4 simulations. The collimator is a 52×52×52 cm{sup 3} polyethylene block coupled with a 1 cm lead sheet in sequence. Composite opening was modeled into the collimator to permit passage of neutrons. The opening varied in shape (cylindrical vs. tapered), size (1–5 cm source-side and target-side openings) and aperture placements (13–39 cm frommore » source-side). Spatial and energy distribution of neutrons and gammas were tracked from each collimator design. Parameters analyzed were primary beam width (FWHM), divergence, and efficiency (percent transmission) for different configurations of the collimator. Select resultant outputs were then used for simulated NSECT imaging of a virtual breast phantom containing a 2.5 cm diameter tumor to assess the effect of the collimator on spatial resolution, noise, and scan time. Finally, composite shielding enclosure made of polyethylene and lead was designed and evaluated to block 99.99% of neutron and gamma radiation generated in the system. Results: Analysis of primary beam indicated the beam-width is linear to the aperture size. Increasing source-side opening allowed at least 20% more neutron throughput for all designs relative to the cylindrical openings. Maximum throughput for all designs was 364% relative to cylindrical openings. Conclusion: The work indicates potential for collimating and shielding a DD neutron generator for use in a clinical NSECT system. The proposed collimator designs produced a well-defined collimated neutron beam that can be used to image samples of interest with millimeter resolution. Balance in output efficiency, noise reduction, and scan time should be considered to determine the optimal design for specific NSECT applications.« less

  14. Analysis and design of fiber-coupled high-power laser diode array

    NASA Astrophysics Data System (ADS)

    Zhou, Chongxi; Liu, Yinhui; Xie, Weimin; Du, Chunlei

    2003-11-01

    A conclusion that a single conventional optical system could not realize fiber coupled high-power laser diode array is drawn based on the BPP of laser beam. According to the parameters of coupled fiber, a method to couple LDA beams into a single multi-mode fiber including beams collimating, shaping, focusing and coupling is present. The divergence angles after collimating are calculated and analyzed; the shape equation of the collimating micro-lenses array is deprived. The focusing lens is designed. A fiber coupled LDA result with the core diameter of 800 um and numeric aperture of 0.37 is gotten.

  15. [Evaluation of Dose Reduction of the Active Collimator in Multi Detector Row CT].

    PubMed

    Ueno, Hiroyuki; Matsubara, Kosuke

    The purpose of this study was to evaluate the performance of active collimator by changing acquisition parameters and obtaining dose profiles in z-axis direction. Dose profiles along z-axis were obtained using XRQA2 Gafchromic film. As a result, the active collimator reduced overranging about 55% compared to that without the active collimator. In addition, by changing the combination of X-ray beam width (32 mm, 40 mm), pitch factor (1.4, 0.6), and the X-ray tube rotation time (0.5 s/rot, 1.0 s/rot), the overranging changed from 19.4 to 34.9 mm. Although the active collimator is effective for reducing overranging, it is necessary to adjust acquisition parameters by taking the properties of the active collimator for acquisition parameters, especially setting beam width, into consideration.

  16. Laser schlieren crystal monitor

    NASA Technical Reports Server (NTRS)

    Owen, Robert B. (Inventor); Johnston, Mary H. (Inventor)

    1987-01-01

    A system and method for monitoring the state of a crystal which is suspended in a solution is described which includes providing a light source for emitting a beam of light along an optical axis. A collimating lens is arranged along the optical axis for collimating the emitted beam to provide a first collimated light beam consisting of parallel light rays. By passing the first collimated light beam through a transparent container, a number of the parallel light rays are deflected off the surfaces of said crystal being monitored according to the refractive index gradient to provide a deflected beam of deflected light rays. A focusing lens is arranged along optical axis for focusing the deflected rays towards a desired focal point. A knife edge is arranged in a predetermined orientation at the focal point; and a screen is provided. A portion of the deflected beam is blocked with the knife edge to project only a portion of the deflected beam. A band is created at one edge of the image of the crystal which indicates the state of change of the surface of the crystal being monitored.

  17. MCNP simulation of a Theratron 780 radiotherapy unit.

    PubMed

    Miró, R; Soler, J; Gallardo, S; Campayo, J M; Díez, S; Verdú, G

    2005-01-01

    A Theratron 780 (MDS Nordion) 60Co radiotherapy unit has been simulated with the Monte Carlo code MCNP. The unit has been realistically modelled: the cylindrical source capsule and its housing, the rectangular collimator system, both the primary and secondary jaws and the air gaps between the components. Different collimator openings, ranging from 5 x 5 cm2 to 20 x 20 cm2 (narrow and broad beams) at a source-surface distance equal to 80 cm have been used during the study. In the present work, we have calculated spectra as a function of field size. A study of the variation of the electron contamination of the 60Co beam has also been performed.

  18. High spatial resolution technique for SPECT using a fan-beam collimator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ichihar, T.; Nambu, K.; Motomura, N.

    1993-08-01

    The physical characteristics of the collimator cause degradation of resolution with increasing distance from the collimator surface. A new convolutional backprojection algorithm has been derived for fanbeam SPECT data without rebinding into parallel beam geometry. The projections are filtered and then backprojected into the area within an isosceles triangle whose vertex is the focal point of the fan-beam and whose base is the fan-beam collimator face, and outside of the circle whose center is located midway between the focal point and the center of rotation and whose diameter is the distance between the focal point and the center of rotation.more » Consequently the backprojected area is close to the collimator surface. This algorithm has been implemented on a GCA-9300A SPECT system showing good results with both phantom and patient studies. The SPECT transaxial resolution was 4.6mm FWHM (reconstructed image matrix size of 256x256) at the center of SPECT FOV using UHR (ultra-high-resolution) fan beam collimators for brain study. Clinically, Tc-99m HMPAO and Tc-99m ECD brain data were reconstructed using this algorithm. The reconstruction results were compared with MRI images of the same slice position and showed significantly improved over results obtained with standard reconstruction algorithms.« less

  19. Can Collimated Extraterrestrial Signals be Intercepted?

    NASA Astrophysics Data System (ADS)

    Forgan, D. H.

    2014-06-01

    The Optical Search for Extraterrestrial Intelligence (OSETI) attempts to detect collimated, narrow-band pulses of electromagnetic radiation. These pulses may either consist of signals intentionally directed at the Earth, or signals between two star systems with a vector that unintentionally intersects the Solar System, allowing Earth to intercept the communication. But should we expect to be able to intercept these unintentional signals? And what constraints can we place upon the frequency of intelligent civilisations if we do? We carry out Monte Carlo Realisation simulations of interstellar communications between civilisations in the Galactic Habitable Zone (GHZ) using collimated beams. We measure the frequency with which beams between two stars are intercepted by a third. The interception rate increases linearly with the fraction of communicating civilisations, and as the cube of the beam opening angle, which is somewhat stronger than theoretical expectations, which we argue is due to the geometry of the GHZ. We find that for an annular GHZ containing 10,000 civilisations, intersections are unlikely unless the beams are relatively uncollimated. These results indicate that optical SETI is more likely to find signals deliberately directed at the Earth than accidentally intercepting collimated communications. Equally, civilisations wishing to establish a network of communicating species may use weakly collimated beams to build up the network through interception, if they are willing to pay a cost penalty that is lower than that meted by fully isotropic beacons. Future SETI searches should consider the possibility that communicating civilisations will attempt to strike a balance between optimising costs and encouraging contact between civilisations, and look for weakly collimated pulses as well as narrow-beam pulses directed deliberately at the Earth.

  20. Dosimetric characteristics of Novalis Tx system with high definition multileaf collimator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chang Zheng; Wang Zhiheng; Wu, Q. Jackie

    A new Novalis Tx system equipped with a high definition multileaf collimator (HDMLC) recently became available to perform both image-guided radiosurgery and conventional radiotherapy. It is capable of delivering a highly conformal radiation dose with three energy modes: 6 MV photon energy, 15 MV photon energy, and 6 MV photon energy in a stereotactic radiosurgery mode with 1000 MU/min dose rate. Dosimetric characteristics of the new Novalis Tx treatment unit with the HDMLC are systematically measured for commissioning. A high resolution diode detector and miniion-chamber detector are used to measure dosimetric data for a range of field sizes from 4x4more » mm to 400x400 mm. The commissioned Novalis Tx system has passed the RPC stereotactic radiosurgery head phantom irradiation test. The Novalis Tx system not only expands its capabilities with three energy modes, but also achieves better beam conformity and sharer beam penumbra with HDMLC. Since there is little beam data information available for the new Novalis Tx system, we present in this work the dosimetric data of the new modality for reference and comparison.« less

  1. Use of capillary optics as a beam intensifier for a Compton x-ray source.

    PubMed

    Tompkins, P A; Abreu, C C; Carroll, F E; Xiao, Q F; MacDonald, C A

    1994-11-01

    The use of Kumakhov capillary optics will significantly enhance the performance of near-monochromatic, Compton backscattered x-ray programs. The Vanderbilt University Medical Free-Electron Laser Center is developing the capability to create these tunable x rays for medical imaging. The present transport has only reflection optics, and the beam is quite large in diameter at the laboratory. Low loss collimation of this beam would allow higher x-ray intensities after transport. This article describes experimental and computer simulation results which predict the expected performance for a multifiber Kumakhov collimator for use in the x-ray beam transport. Estimates from our research are that a multifiber optic formed of individual polycapillary fibers could be used to capture the full 7 mrad of the Vanderbilt x-ray beam and collimate it to a 1-2 mrad divergence with approximately 40%-50% transmission efficiency. This optic should increase the x-ray intensity at the laboratory level by a factor of > or = 5 by decreasing the beam divergence and subsequent spot size. Additionally, analysis of monolithic optics of fused multicapillary fibers predicts an increase in the intensity of the x rays at the laboratory by a factor of 55. These optics can have tapered channels that greatly decrease their exit divergence. This will greatly enhance the capabilities of this unique x-ray source. This article reports the initial results from a collaboration between Vanderbilt, The Center for X-Ray Optics at University at Albany, SUNY, and X-Ray Optical Systems in Albany, NY.

  2. Study on initiative vibration absorbing technology of optics in strong disturbed environment

    NASA Astrophysics Data System (ADS)

    Jia, Si-nan; Xiong, Mu-di; Zou, Xiao-jie

    2007-12-01

    Strong disturbed environment is apt to cause irregular vibration, which seriously affects optical collimation. To improve the performance of laser beam, three-point dynamic vibration absorbing method is proposed, and laser beam initiative vibration absorbing system is designed. The maladjustment signal is detected by position sensitive device (PSD), three groups of PZT are driven to adjust optical element in real-time, so the performance of output-beam is improved. The coupling model of the system is presented. Multivariable adaptive closed-loop decoupling arithmetic is used to design three-input-three-output decoupling controller, so that high precision dynamic adjusting is realized. Experiments indicate that the system has good shock absorbing efficiency.

  3. Two self-referencing methods for the measurement of beam spot position.

    PubMed

    Nyiri, Balazs J; Smale, Jason R; Gerig, Lee H

    2012-12-01

    Two quantitative methods of measuring electron beam spot position with respect to the collimator axis of rotation (CAOR) are described. Method 1 uses a cylindrical ion chamber (IC) mounted on a jig corotational with the collimator making the relationship among the chamber, jaws, and CAOR fixed and independent of collimator angle. A jaw parallel to the IC axis is set to zero and the IC position adjusted so that the IC signal is approximately 50% of the open field value, providing a large dose gradient in the region of the IC. The cGy∕MU value is measured as a function of collimator rotation, e.g., every 30°. If the beam spot does not lie on the CAOR, the signal from the ion chamber will vary with collimator rotation. Based on a measured spatial sensitivity, the distance of the beam spot from the CAOR can be calculated from the IC signal variation with rotation. The 2nd method is image based. Two stainless steel rods, 3 mm in diameter, are mounted to a jig attached to the Linac collimator. The rods, offset from the CAOR, lay in different planes normal to the CAOR, one at 158 cm SSD and the other at 70 cm SSD. As the collimator rotates the rods move tangent along an envelope circle, the centers of which are on the CAOR in their respective planes. Three images, each at a different collimator rotation, containing the shadows of both rods, are acquired on the Linac EPID. At each angle the shadow of the rods on the EPID defines lines tangent to the projection of the envelope circles. From these the authors determine the projected centers of the two circles at different heights. From the distance of these two points using the two heights and the source to EPID distance, the authors calculate the distance of the beam spot from the CAOR. Measurements with all two techniques were performed on an Elekta Linac. Measurements were performed with the beam spot in nominal clinical position and in a deliberately offset position. Measurements were also performed using the Flexmap image registration∕ball-bearing test. Within their uncertainties, both methods report the same beam spot displacement. In clinical use, a total of 203 monthly beam spot measurements on 14 different beams showed an average displacement of 0.11 mm (σ = 0.07 mm) in-plane and 0.10 mm (σ = 0.07 mm) cross-plane with maximum displacement of 0.37 mm in-plane and 0.34 mm cross-plane. The methods described provide a quantitative measure of beam spot position, are easy to use, and provide another tool for Linac setup and quality assurance. Fundamental to the techniques is that they are self-referencing-i.e., they do not require the user to independently define the CAOR.

  4. Two self-referencing methods for the measurement of beam spot position

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nyiri, Balazs J.; Smale, Jason R.; Gerig, Lee H.

    2012-12-15

    Purpose: Two quantitative methods of measuring electron beam spot position with respect to the collimator axis of rotation (CAOR) are described. Methods: Method 1 uses a cylindrical ion chamber (IC) mounted on a jig corotational with the collimator making the relationship among the chamber, jaws, and CAOR fixed and independent of collimator angle. A jaw parallel to the IC axis is set to zero and the IC position adjusted so that the IC signal is approximately 50% of the open field value, providing a large dose gradient in the region of the IC. The cGy/MU value is measured as amore » function of collimator rotation, e.g., every 30 Degree-Sign . If the beam spot does not lie on the CAOR, the signal from the ion chamber will vary with collimator rotation. Based on a measured spatial sensitivity, the distance of the beam spot from the CAOR can be calculated from the IC signal variation with rotation. The 2nd method is image based. Two stainless steel rods, 3 mm in diameter, are mounted to a jig attached to the Linac collimator. The rods, offset from the CAOR, lay in different planes normal to the CAOR, one at 158 cm SSD and the other at 70 cm SSD. As the collimator rotates the rods move tangent along an envelope circle, the centers of which are on the CAOR in their respective planes. Three images, each at a different collimator rotation, containing the shadows of both rods, are acquired on the Linac EPID. At each angle the shadow of the rods on the EPID defines lines tangent to the projection of the envelope circles. From these the authors determine the projected centers of the two circles at different heights. From the distance of these two points using the two heights and the source to EPID distance, the authors calculate the distance of the beam spot from the CAOR. Measurements with all two techniques were performed on an Elekta Linac. Measurements were performed with the beam spot in nominal clinical position and in a deliberately offset position. Measurements were also performed using the Flexmap image registration/ball-bearing test. Results: Within their uncertainties, both methods report the same beam spot displacement. In clinical use, a total of 203 monthly beam spot measurements on 14 different beams showed an average displacement of 0.11 mm ({sigma}= 0.07 mm) in-plane and 0.10 mm ({sigma}= 0.07 mm) cross-plane with maximum displacement of 0.37 mm in-plane and 0.34 mm cross-plane. Conclusions: The methods described provide a quantitative measure of beam spot position, are easy to use, and provide another tool for Linac setup and quality assurance. Fundamental to the techniques is that they are self-referencing-i.e., they do not require the user to independently define the CAOR.« less

  5. Evaluating Red Reflex and Surgeon Preference Between Nearly-Collimated and Focused Beam Microscope Illumination Systems

    PubMed Central

    Cionni, Robert J.; Pei, Ron; Dimalanta, Ramon; Lubeck, David

    2015-01-01

    Purpose To evaluate the intensity and stability of the red reflex produced by ophthalmic surgical microscopes with nearly-collimated versus focused illumination systems and to assess surgeon preference in a simulated surgical setting. Methods This two-part evaluation consisted of postproduction surgical video analysis of red reflex intensity and a microscope use and preference survey completed by 13 experienced cataract surgeons. Survey responses were based on bench testing and experience in a simulated surgical setting. A microscope with nearly-collimated beam illumination and two focused beam microscopes were assessed. Results Red reflex intensity and stability were greater with the nearly-collimated microscope illumination system. In the bench testing survey, surgeons reported that the red reflex was maintained over significantly greater distances away from pupillary center, and depth of focus was numerically greater with nearly-collimated illumination relative to focused illumination. Most participating surgeons (≥64%) reported a preference for the microscope with nearly-collimated illumination with regard to red reflex stability, depth of focus, visualization, surgical working distance, and perceived patient comfort. Conclusions The microscope with nearly-collimated illumination produced a more intense and significantly more stable red reflex and was preferred overall by more surgeons. Translational Relevance This is the first report of an attempt to quantify red reflex intensity and stability and to evaluate surgically-relevant parameters between microscope systems. The data and methods presented here may provide a basis for future studies attempting to quantify differences between surgical microscopes that may affect surgeon preference and microscope use in ophthalmic surgery. PMID:26290778

  6. Prompt gamma imaging of proton pencil beams at clinical dose rate

    NASA Astrophysics Data System (ADS)

    Perali, I.; Celani, A.; Bombelli, L.; Fiorini, C.; Camera, F.; Clementel, E.; Henrotin, S.; Janssens, G.; Prieels, D.; Roellinghoff, F.; Smeets, J.; Stichelbaut, F.; Vander Stappen, F.

    2014-10-01

    In this work, we present experimental results of a prompt gamma camera for real-time proton beam range verification. The detection system features a pixelated Cerium doped lutetium based scintillation crystal, coupled to Silicon PhotoMultiplier arrays, read out by dedicated electronics. The prompt gamma camera uses a knife-edge slit collimator to produce a 1D projection of the beam path in the target on the scintillation detector. We designed the detector to provide high counting statistics and high photo-detection efficiency for prompt gamma rays of several MeV. The slit design favours the counting statistics and could be advantageous in terms of simplicity, reduced cost and limited footprint. We present the description of the realized gamma camera, as well as the results of the characterization of the camera itself in terms of imaging performance. We also present the results of experiments in which a polymethyl methacrylate phantom was irradiated with proton pencil beams in a proton therapy center. A tungsten slit collimator was used and prompt gamma rays were acquired in the 3-6 MeV energy range. The acquisitions were performed with the beam operated at 100 MeV, 160 MeV and 230 MeV, with beam currents at the nozzle exit of several nA. Measured prompt gamma profiles are consistent with the simulations and we reached a precision (2σ) in shift retrieval of 4 mm with 0.5 × 108, 1.4 × 108 and 3.4 × 108 protons at 100, 160 and 230 MeV, respectively. We conclude that the acquisition of prompt gamma profiles for in vivo range verification of proton beam with the developed gamma camera and a slit collimator is feasible in clinical conditions. The compact design of the camera allows its integration in a proton therapy treatment room and further studies will be undertaken to validate the use of this detection system during treatment of real patients.

  7. Measurements of beam halo diffusion and population density in the Tevatron and in the Large Hadron Collider

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stancari, Giulio

    2015-03-01

    Halo dynamics influences global accelerator performance: beam lifetimes, emittance growth, dynamic aperture, and collimation efficiency. Halo monitoring and control are also critical for the operation of high-power machines. For instance, in the high-luminosity upgrade of the LHC, the energy stored in the beam tails may reach several megajoules. Fast losses can result in superconducting magnet quenches, magnet damage, or even collimator deformation. The need arises to measure the beam halo and to remove it at controllable rates. In the Tevatron and in the LHC, halo population densities and diffusivities were measured with collimator scans by observing the time evolution ofmore » losses following small inward or outward collimator steps, under different experimental conditions: with single beams and in collision, and, in the case of the Tevatron, with a hollow electron lens acting on a subset of bunches. After the LHC resumes operations, it is planned to compare measured diffusivities with the known strength of transverse damper excitations. New proposals for nondestructive halo population density measurements are also briefly discussed.« less

  8. Spatial resolution test of a beam diagnostic system for DESIREE

    NASA Astrophysics Data System (ADS)

    Das, Susanta; Kallberg, A.

    2010-11-01

    A diagnostic system based on the observation of low energy ( ˜ 10 eV) secondary electrons (SE) produced by a beam, striking a metallic foil has been built to monitor and to cover the wide range of beam intensities and energies for Double ElectroStatic Ion Ring ExpEriment [1,2].The system consists of a Faraday cup to measure the beam current, a collimator with circular apertures of different diameters to measure the spatial resolution of the system, a beam profile monitoring system (BPMS), and a control unit. The BPMS, in turn, consists of an aluminim (Al) foil, a grid placed in front of the Al foil to accelerate the SE, position sensitive MCP, fluorescent screen, and a CCD camera to capture the images. The collimator contains a set of circular holes of different diameters and separations (d) between them. The collimator cuts out from the beam areas equal to the holes with separation d mm between the beams centers and creates well separated (distinguishable) narrow beams of approximately same intensity close to each other. A 10 keV proton beam was used. The spatial resolution of the system was tested for different Al plate and MCP voltages and resolution of better than 2 mm was achieved. Ref.: 1. K. Kruglov {et al}., NIM A 441 (2000) 595; 701 (2002) 193c, 2. MSL and Atomic Physics, Stockholm Univ.(www.msl.se, http://www.atom.physto.se/Cederquist/desiree/web/hc.html).

  9. Adaptation, Commissioning, and Evaluation of a 3D Treatment Planning System for High-Resolution Small-Animal Irradiation

    PubMed Central

    Jeong, Jeho; Chen, Qing; Febo, Robert; Yang, Jie; Pham, Hai; Xiong, Jian-Ping; Zanzonico, Pat B.; Deasy, Joseph O.; Humm, John L.; Mageras, Gig S.

    2016-01-01

    Although spatially precise systems are now available for small-animal irradiations, there are currently limited software tools available for treatment planning for such irradiations. We report on the adaptation, commissioning, and evaluation of a 3-dimensional treatment planning system for use with a small-animal irradiation system. The 225-kV X-ray beam of the X-RAD 225Cx microirradiator (Precision X-Ray) was commissioned using both ion-chamber and radiochromic film for 10 different collimators ranging in field size from 1 mm in diameter to 40 × 40 mm2. A clinical 3-dimensional treatment planning system (Metropolis) developed at our institution was adapted to small-animal irradiation by making it compatible with the dimensions of mice and rats, modeling the microirradiator beam orientations and collimators, and incorporating the measured beam data for dose calculation. Dose calculations in Metropolis were verified by comparison with measurements in phantoms. Treatment plans for irradiation of a tumor-bearing mouse were generated with both the Metropolis and the vendor-supplied software. The calculated beam-on times and the plan evaluation tools were compared. The dose rate at the central axis ranges from 74 to 365 cGy/min depending on the collimator size. Doses calculated with Metropolis agreed with phantom measurements within 3% for all collimators. The beam-on times calculated by Metropolis and the vendor-supplied software agreed within 1% at the isocenter. The modified 3-dimensional treatment planning system provides better visualization of the relationship between the X-ray beams and the small-animal anatomy as well as more complete dosimetric information on target tissues and organs at risk. It thereby enhances the potential of image-guided microirradiator systems for evaluation of dose–response relationships and for preclinical experimentation generally. PMID:25948321

  10. Understanding space charge and controlling beam loss in high intensity synchrotrons

    NASA Astrophysics Data System (ADS)

    Cousineau, Sarah M.

    Future high intensity synchrotrons will require unprecedented control of beam loss in order to comply with radiation safety regulations and to allow for safe, hands-on maintenance of machine hardware. A major cause of beam loss in high intensity synchrotrons is the space charge force of the beam, which can lead to beam halo and emittance dilution. This dissertation presents a comprehensive study of space charge effects in high intensity synchrotron beams. Experimental measurements taken at the Proton Storage Ring (PSR) in Los Alamos National Laboratory and detailed simulations of the experiments are used to identify and characterize resonances that affect these beams. The collective motion of the beam is extensively studied and is shown to be more relevant than the single particle dynamics in describing the resonance response. The emittance evolution of the PSR beam and methods for reducing the space-charge-induced emittance growth are addressed. In a separate study, the emittance evolution of an intense space charge beam is experimentally measured at the Cooler Injector Synchrotron (CIS) at Indiana University. This dissertation also investigates the sophisticated two-stage collimation system of the future Spallation Neutron Source (SNS) high intensity accumulator ring. A realistic Monte-Carlo collimation simulation is developed and used to optimize the SNS ring collimation system parameters. The finalized parameters and predicted beam loss distribution around the ring are presented. The collimators will additionally be used in conjunction with a set of fast kickers to remove the beam from the gap region before the rise of the extraction magnets. The gap cleaning process is optimized and the cleaning efficiency versus momentum spread of the beam is examined.

  11. Stimulated Brillouin scattering mirror system, high power laser and laser peening method and system using same

    DOEpatents

    Dane, C Brent [Livermore, CA; Hackel, Lloyd [Livermore, CA; Harris, Fritz B [Rocklin, CA

    2007-04-24

    A laser system, such as a master oscillator/power amplifier system, comprises a gain medium and a stimulated Brillouin scattering SBS mirror system. The SBS mirror system includes an in situ filtered SBS medium that comprises a compound having a small negative non-linear index of refraction, such as a perfluoro compound. An SBS relay telescope having a telescope focal point includes a baffle at the telescope focal point which blocks off angle beams. A beam splitter is placed between the SBS mirror system and the SBS relay telescope, directing a fraction of the beam to an alternate beam path for an alignment fiducial. The SBS mirror system has a collimated SBS cell and a focused SBS cell. An adjustable attenuator is placed between the collimated SBS cell and the focused SBS cell, by which pulse width of the reflected beam can be adjusted.

  12. SU-E-T-453: A Novel Daily QA System for Robotic Image Guided Radiosurgery with Variable Aperture Collimator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, L; Nelson, B

    Purpose: A novel end-to-end system using a CCD camera and a scintillator based phantom that is capable of measuring the beam-by-beam delivery accuracy of Robotic Radiosurgery has been developed and reported in our previous work. This work investigates its application to end-to-end type daily QA for Robotic Radiosurgery (Cyberknife) with Variable Aperture Collimator (Iris). Methods: The phantom was first scanned with a CT scanner at 0.625 slice thickness and exported to the Cyberknife Muliplan (v4.6) treatment planning system. An isocentric treatment plan was created consisting of ten beams of 25 Monitor Units each using Iris apertures of 7.5, 10, 15,more » 20, and 25 mm. The plan was delivered six times in two days on the Cyberknife G4 system with fiducial tracking on the four metal fiducials embedded in phantom with re-positioning between the measurements. The beam vectors (X, Y, Z) are measured and compared with the plan from the machine delivery file (XML file). The Iris apertures (FWHM) were measured from the beam flux map and compared with the commissioning data. Results: The average beam positioning accuracies of the six deliveries are 0.71 ± 0.40 mm, 0.72 ± 0.44 mm, 0.74 ± 0.42 mm, 0.70 ± 0.40 mm, 0.79 ± 0.44 mm and 0.69 ± 0.41 mm respectively. Radiation beam width (FWHM) variations are within ±0.05 mm, and they agree with the commissioning data within 0.22 mm. The delivery time for the plan is about 7 minutes and the results are given instantly. Conclusion: The experimental results agree with stated sub-millimeter delivery accuracy of Cyberknife system. Beam FWHM variations comply with the 0.2 mm accuracy of the Iris collimator at SAD. The XRV-100 system has proven to be a powerful tool in performing end-to-end type tests for Robotic Image Guided Radiosurgery Daily QA.« less

  13. Characteristics and performance of the first commercial multileaf collimator for a robotic radiosurgery system.

    PubMed

    Fürweger, Christoph; Prins, Paulette; Coskan, Harun; Heijmen, Ben J M

    2016-05-01

    The "InCise™ multileaf-collimator (MLC)" is the first commercial MLC to be mounted on a robotic SRS/SBRT platform (CyberKnife). The authors assessed characteristics and performance of this novel device in a preclinical five months test period. Commissioning beam data were acquired with unshielded diodes. EBT3 radiochromic films were employed for measurement of transmission, leaf/bank position accuracy (garden fence) before and after exercising the MLC, for end-to-end testing and further characterization of the beam. The robot workspace with MLC was assessed analytically by transformation to an Euler geometry ("plane," "gantry," and "collimator" angles) and by measuring pointing accuracy at each node. Stability over time was evaluated in picket fence and adapted Winston-Lutz tests (AQA). Beam penumbrae (80%-20%, with 100% = 2 × dose at inflection point for field sizes ≥ 50 × 50 mm(2)) were 2.2-3.7 mm for square fields in reference condition (source-axis-distance 800 mm, depth 15 mm) and depended on field size and off-axis position. Transmission and leakage did not exceed 0.5%. Accessible clinical workspace with MLC covered non-coplanar gantry angles of [-113°; +112°] and collimator angles of [-100°; +107°], with an average robot pointing accuracy of 0.12 ± 0.09 mm. For vertical beams, garden fence tests exhibited an average leaf positioning error of ≤0.2 mm, which increased by 0.25 and 0.30 mm (banks X1 and X2) with leaves traveling parallel to gravity. After execution of a leaf motion stress routine, garden fence tests showed slightly increased jaggedness and allowed to identify one malfunctioning leaf motor. Total system accuracy with MLC was 0.38 ± 0.05 mm in nine end-to-end tests. Picket fence and AQA tests displayed stable results over the test period. The InCise™ MLC for CyberKnife showed high accuracy and adequate characteristics for SRS/SBRT applications. MLC performance after exercise demands specific quality assurance measures.

  14. Method for pulse control in a laser including a stimulated brillouin scattering mirror system

    DOEpatents

    Dane, C. Brent; Hackel, Lloyd; Harris, Fritz B.

    2007-10-23

    A laser system, such as a master oscillator/power amplifier system, comprises a gain medium and a stimulated Brillouin scattering SBS mirror system. The SBS mirror system includes an in situ filtered SBS medium that comprises a compound having a small negative non-linear index of refraction, such as a perfluoro compound. An SBS relay telescope having a telescope focal point includes a baffle at the telescope focal point which blocks off angle beams. A beam splitter is placed between the SBS mirror system and the SBS relay telescope, directing a fraction of the beam to an alternate beam path for an alignment fiducial. The SBS mirror system has a collimated SBS cell and a focused SBS cell. An adjustable attenuator is placed between the collimated SBS cell and the focused SBS cell, by which pulse width of the reflected beam can be adjusted.

  15. Ion beam collimating grid to reduce added defects

    DOEpatents

    Lindquist, Walter B.; Kearney, Patrick A.

    2003-01-01

    A collimating grid for an ion source located after the exit grid. The collimating grid collimates the ion beamlets and disallows beam spread and limits the beam divergence during transients and steady state operation. The additional exit or collimating grid prevents beam divergence during turn-on and turn-off and prevents ions from hitting the periphery of the target where there is re-deposited material or from missing the target and hitting the wall of the vessel where there is deposited material, thereby preventing defects from being deposited on a substrate to be coated. Thus, the addition of a collimating grid to an ion source ensures that the ion beam will hit and be confined to a specific target area.

  16. Multiple pinhole collimator based X-ray luminescence computed tomography

    PubMed Central

    Zhang, Wei; Zhu, Dianwen; Lun, Michael; Li, Changqing

    2016-01-01

    X-ray luminescence computed tomography (XLCT) is an emerging hybrid imaging modality, which is able to improve the spatial resolution of optical imaging to hundreds of micrometers for deep targets by using superfine X-ray pencil beams. However, due to the low X-ray photon utilization efficiency in a single pinhole collimator based XLCT, it takes a long time to acquire measurement data. Herein, we propose a multiple pinhole collimator based XLCT, in which multiple X-ray beams are generated to scan a sample at multiple positions simultaneously. Compared with the single pinhole based XLCT, the multiple X-ray beam scanning method requires much less measurement time. Numerical simulations and phantom experiments have been performed to demonstrate the feasibility of the multiple X-ray beam scanning method. In one numerical simulation, we used four X-ray beams to scan a cylindrical object with 6 deeply embedded targets. With measurements from 6 angular projections, all 6 targets have been reconstructed successfully. In the phantom experiment, we generated two X-ray pencil beams with a collimator manufactured in-house. Two capillary targets with 0.6 mm edge-to-edge distance embedded in a cylindrical phantom have been reconstructed successfully. With the two beam scanning, we reduced the data acquisition time by 50%. From the reconstructed XLCT images, we found that the Dice similarity of targets is 85.11% and the distance error between two targets is less than 3%. We have measured the radiation dose during XLCT scan and found that the radiation dose, 1.475 mSv, is in the range of a typical CT scan. We have measured the changes of the collimated X-ray beam size and intensity at different distances from the collimator. We have also studied the effects of beam size and intensity in the reconstruction of XLCT. PMID:27446686

  17. A comparison of two prompt gamma imaging techniques with collimator-based cameras for range verification in proton therapy

    NASA Astrophysics Data System (ADS)

    Lin, Hsin-Hon; Chang, Hao-Ting; Chao, Tsi-Chian; Chuang, Keh-Shih

    2017-08-01

    In vivo range verification plays an important role in proton therapy to fully utilize the benefits of the Bragg peak (BP) for delivering high radiation dose to tumor, while sparing the normal tissue. For accurately locating the position of BP, camera equipped with collimators (multi-slit and knife-edge collimator) to image prompt gamma (PG) emitted along the proton tracks in the patient have been proposed for range verification. The aim of the work is to compare the performance of multi-slit collimator and knife-edge collimator for non-invasive proton beam range verification. PG imaging was simulated by a validated GATE/GEANT4 Monte Carlo code to model the spot-scanning proton therapy and cylindrical PMMA phantom in detail. For each spot, 108 protons were simulated. To investigate the correlation between the acquired PG profile and the proton range, the falloff regions of PG profiles were fitted with a 3-line-segment curve function as the range estimate. Factors including the energy window setting, proton energy, phantom size, and phantom shift that may influence the accuracy of detecting range were studied. Results indicated that both collimator systems achieve reasonable accuracy and good response to the phantom shift. The accuracy of range predicted by multi-slit collimator system is less affected by the proton energy, while knife-edge collimator system can achieve higher detection efficiency that lead to a smaller deviation in predicting range. We conclude that both collimator systems have potentials for accurately range monitoring in proton therapy. It is noted that neutron contamination has a marked impact on range prediction of the two systems, especially in multi-slit system. Therefore, a neutron reduction technique for improving the accuracy of range verification of proton therapy is needed.

  18. Development of a Method to Assess the Precision Of the z-axis X-ray Beam Collimation in a CT Scanner

    NASA Astrophysics Data System (ADS)

    Kim, Yon-Min

    2018-05-01

    Generally X-ray equipment specifies the beam collimator for the accuracy measurement as a quality control item, but the computed tomography (CT) scanner with high dose has no collimator accuracy measurement item. If the radiation dose is to be reduced, an important step is to check if the beam precisely collimates at the body part for CT scan. However, few ways are available to assess how precisely the X-ray beam is collimated. In this regard, this paper provides a way to assess the precision of z-axis X-ray beam collimation in a CT scanner. After the image plate cassette had been exposed to the X-ray beam, the exposed width was automatically detected by using a computer program developed by the research team to calculate the difference between the exposed width and the imaged width (at isocenter). The result for the precision of z-axis X-ray beam collimation showed that the exposed width was 3.8 mm and the overexposure was high at 304% when a narrow beam of a 1.25 mm imaged width was used. In this study, the precision of the beam collimation of the CT scanner, which is frequently used for medical services, was measured in a convenient way by using the image plate (IP) cassette.

  19. All-reflective optical target illumination system with high numerical aperture

    DOEpatents

    Thomas, Carlton E.; Sigler, Robert D.; Hoeger, John G.

    1979-01-01

    An all-reflective optical system for providing illumination of a target focal region at high numerical aperture from a pair of confluent collimated light beams. The collimated beams are each incident upon an associated concave eccentric pupil paraboloidal reflective surface, and thereby each focused through an opening in an associated outer ellipsoidal reflective surface onto a plane reflector. Each beam is reflected by its associated plane reflector onto the opposing concave surface of the outer ellipsoids to be focused through an opening in the plane surface onto an opposing inner concave ellipsoidal reflective surface, and thence onto the target region.

  20. Electron beam collimation with a photon MLC for standard electron treatments

    NASA Astrophysics Data System (ADS)

    Mueller, S.; Fix, M. K.; Henzen, D.; Frei, D.; Frauchiger, D.; Loessl, K.; Stampanoni, M. F. M.; Manser, P.

    2018-01-01

    Standard electron treatments are currently still performed using standard or molded patient-specific cut-outs placed in the electron applicator. Replacing cut-outs and electron applicators with a photon multileaf collimator (pMLC) for electron beam collimation would make standard electron treatments more efficient and would facilitate advanced treatment techniques like modulated electron radiotherapy (MERT) and mixed beam radiotherapy (MBRT). In this work, a multiple source Monte Carlo beam model for pMLC shaped electron beams commissioned at a source-to-surface distance (SSD) of 70 cm is extended for SSDs of up to 100 cm and validated for several Varian treatment units with field sizes typically used for standard electron treatments. Measurements and dose calculations agree generally within 3% of the maximal dose or 2 mm distance to agreement. To evaluate the dosimetric consequences of using pMLC collimated electron beams for standard electron treatments, pMLC-based and cut-out-based treatment plans are created for a left and a right breast boost, a sternum, a testis and a parotid gland case. The treatment plans consist of a single electron field, either alone (1E) or in combination with two 3D conformal tangential photon fields (1E2X). For each case, a pMLC plan with similar treatment plan quality in terms of dose homogeneity to the target and absolute mean dose values to the organs at risk (OARs) compared to a cut-out plan is found. The absolute mean dose to an OAR is slightly increased for pMLC-based compared to cut-out-based 1E plans if the OAR is located laterally close to the target with respect to beam direction, or if a 6 MeV electron beam is used at an extended SSD. In conclusion, treatment plans using cut-out collimation can be replaced by plans of similar treatment plan quality using pMLC collimation with accurately calculated dose distributions.

  1. Multispectral scanner optical system

    NASA Technical Reports Server (NTRS)

    Stokes, R. C.; Koch, N. G. (Inventor)

    1980-01-01

    An optical system for use in a multispectral scanner of the type used in video imaging devices is disclosed. Electromagnetic radiation reflected by a rotating scan mirror is focused by a concave primary telescope mirror and collimated by a second concave mirror. The collimated beam is split by a dichroic filter which transmits radiant energy in the infrared spectrum and reflects visible and near infrared energy. The long wavelength beam is filtered and focused on an infrared detector positioned in a cryogenic environment. The short wavelength beam is dispersed by a pair of prisms, then projected on an array of detectors also mounted in a cryogenic environment and oriented at an angle relative to the optical path of the dispersed short wavelength beam.

  2. Introduction of a novel ultrahigh sensitivity collimator for brain SPECT imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, Mi-Ae, E-mail: miaepark@bwh.harvard.edu; Kij

    Purpose: Noise levels of brain SPECT images are highest in central regions, due to preferential attenuation of photons emitted from deep structures. To address this problem, the authors have designed a novel collimator for brain SPECT imaging that yields greatly increased sensitivity near the center of the brain without loss of resolution. This hybrid collimator consisted of ultrashort cone-beam holes in the central regions and slant-holes in the periphery (USCB). We evaluated this collimator for quantitative brain imaging tasks. Methods: Owing to the uniqueness of the USCB collimation, the hole pattern required substantial variations in collimator parameters. To utilize themore » lead-casting technique, the authors designed two supporting plates to position about 37 000 hexagonal, slightly tapered pins. The holes in the supporting plates were modeled to yield the desired focal length, hole length, and septal thickness. To determine the properties of the manufactured collimator and to compute the system matrix, the authors prepared an array of point sources that covered the entire detector area. Each point source contained 32 μCi of Tc-99m at the first scan time. The array was imaged for 5 min at each of the 64 shifted locations to yield a 2-mm sampling distance, and hole parameters were calculated. The sensitivity was also measured using a point source placed along the central ray at several distances from the collimator face. High-count projection data from a five-compartment brain phantom were acquired with the three collimators on a dual-head SPECT/CT system. The authors calculated Cramer-Rao bounds on the precision of estimates of striatal and background activity concentration. In order to assess the new collimation system to detect changes in striatal activity, the authors evaluated the precision of measuring a 5% decrease in right putamen activity. The authors also reconstructed images of projection data obtained by summing data from the individual phantom compartments. Results: The sensitivity of the novel cone-beam collimator varied with distance from the detector face; it was higher than that of the fan-beam collimator by factors ranging from 2.7 to 162. Examination of the projections of the point sources revealed that only a few holes were distorted or partially blocked, indicating that the intensive manual fabrication process was very successful. Better reconstructed phantom images were obtained from the USCB+FAN collimator pair than from either LEHR or FAN collimation. For the left caudate, located near the center of the brain, the detected counts were 9.8 (8.3) times higher for UCSB compared with LEHR (FAN), averaged over 60 views. The task-specific SNR for detecting a 5% decrease in putamen uptake was 7.4 for USCB and 3.2 for LEHR. Conclusions: The authors have designed and manufactured a novel collimator for brain SPECT imaging. The sensitivity is much higher than that of a fan-beam collimator. Because of differences between the manufactured collimator and its design, reconstruction of the data requires a measured system matrix. The authors have demonstrated the potential of USCB collimation for improved precision in estimating striatal uptake. The novel collimator may be useful for early detection of Parkinson’s disease, and for monitoring therapy response and disease progression.« less

  3. EPR/alanine dosimetry for two therapeutic proton beams

    NASA Astrophysics Data System (ADS)

    Marrale, Maurizio; Carlino, Antonio; Gallo, Salvatore; Longo, Anna; Panzeca, Salvatore; Bolsi, Alessandra; Hrbacek, Jan; Lomax, Tony

    2016-02-01

    In this work the analysis of the electron paramagnetic resonance (EPR) response of alanine pellets exposed to two different clinical proton beams employed for radiotherapy is performed. One beam is characterized by a passive delivery technique and is dedicated to the eyes treatment (OPTIS2 beam line). Alanine pellets were irradiated with a 70 MeV proton beam corresponding to 35 mm range in eye tissue. We investigated how collimators with different sizes and shape used to conform the dose to the planned target volume influence the delivered dose. For this purpose we performed measurements with varying the collimator size (Output Factor) and the results were compared with those obtained with other dosimetric techniques (such as Markus chamber and diode detector). This analysis showed that the dosimeter response is independent of collimator diameter if this is larger than or equal to 10 mm. The other beam is characterized by an active spot-scanning technique, the Gantry1 beam line (maximum energy 230 MeV), and is used to treat deep-seated tumors. The dose linearity of alanine response in the clinical dose range was tested and the alanine dose response at selected locations in depth was measured and compared with the TPS planned dose in a quasi-clinical scenario. The alanine response was found to be linear in the dose in the clinical explored range (from 10 to 70 Gy). Furthermore, a depth dose profile in a quasi-clinical scenario was measured and compared to the dose computed by the Treatment Planning System PSIPLAN. The comparison of calibrated proton alanine measurements and TPS dose shows a difference under 1% in the SOBP and a "quenching" effect up to 4% in the distal part of SOBP. The positive dosimetric characteristics of the alanine pellets confirm the feasibility to use these detectors for "in vivo" dosimetry in clinical proton beams.

  4. Poster - 23: Dosimetric Characterization and Transferability of an Accessory Mounted Mini-Beam Collimator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, William; Crewson, Cody; Alexander, Andrew

    Objective: The dosimetric characterization of an accessory-mounted mini-beam collimator across three beam matched linear accelerators. Materials and Methods: Percent depth dose and profiles were measured for the open and mini-beam collimated fields. The average beam quality and peak-to-valley dose ratio (PVDR), the ratio of average peak dose to average valley dose, were obtained from these measurements. The open field relative output and the mini-beam collimator factor, the ratio of the mini-beam dose to open field dose at the beam center, were measured for square fields of side 2, 3, 4, and 5 cm. Mini-beam output as a function of collimatormore » inclination angle relative to the central axis was also investigated. Results and Discussion: Beam quality for both the open and mini-beam collimated fields agreed across all linacs to within ±1.0%. The PVDR was found to vary by up to ±6.6% from the mean. For the 2, 3, and 4 cm fields the average open field relative output with respect to the 5 cm field was 0.874±0.4%, 0.921±0.3%, and 0.962±0.1%. The average collimator factors were 0.450±3.9%, 0.443±3.9%, 0.438±3.9%, and 0.434±3.9%. A decrease in collimator factor greater than 7% was found for an inclination angle change of 0.09°. Conclusion: The mini-beam collimator has revealed a difference between the three linacs not apparent in the open field data, yet transferability can still be attained through thorough dosimetric characterization.« less

  5. High efficiency ion beam accelerator system

    NASA Technical Reports Server (NTRS)

    Aston, G.

    1981-01-01

    An ion accelerator system that successfully combines geometrical and electrostatic focusing principles is presented. This accelerator system uses thin, concave, multiple-hole, closely spaced graphite screen and focusing grids which are coupled to single slot accelerator and decelerator grids to provide high ion extraction efficiency and good focusing. Tests with the system showed a substantial improvement in ion beam current density and collimation as compared with a Pierce electrode configuration. Durability of the thin graphite screen and focusing grids has been proven, and tests are being performed to determine the minimum screen and focusing grid spacing and thickness required to extract the maximum reliable beam current density. Compared with present neutral beam injector accelerator systems, this one has more efficient ion extraction, easier grid alignment, easier fabrication, a less cumbersome design, and the capacity to be constructed in a modular fashion. Conceptual neutral beam injector designs using this modular approach have electrostatic beam deflection plates downstream of each module.

  6. Characterization of equipment for shaping and imaging hadron minibeams

    NASA Astrophysics Data System (ADS)

    Pugatch, V.; Brons, S.; Campbell, M.; Kovalchuk, O.; Llopart, X.; Martínez-Rovira, I.; Momot, Ie.; Okhrimenko, O.; Prezado, Y.; Sorokin, Yu.

    2017-11-01

    For the feasibility studies of spatially fractionated hadron therapy prototypes of the equipment for hadron minibeams shaping and monitoring have been designed, built and tested. The collimators design was based on Monte Carlo simulations (Gate v.6.2). Slit and matrix collimators were used for minibeams shaping. Gafchromic films, micropixel detectors Timepix in a hybrid as well as metal mode were tested for measuring hadrons intensity distribution in minibeams. An overall beam profile was measured by the metal microstrip detector. The performance of a mini-beams shaping and monitoring equipment was characterized exploring low energy protons at the KINR Tandem generator as well as high energy carbon and oxygen ion beams at HIT (Heidelberg). The results demonstrate reliable performance of the tested equipment for shaping and imaging hadron mini-beam structures.

  7. Design of a fast multileaf collimator for radiobiological optimized IMRT with scanned beams of photons, electrons, and light ions.

    PubMed

    Svensson, Roger; Larsson, Susanne; Gudowska, Irena; Holmberg, Rickard; Brahme, Anders

    2007-03-01

    Intensity modulated radiation therapy is rapidly becoming the treatment of choice for most tumors with respect to minimizing damage to the normal tissues and maximizing tumor control. Today, intensity modulated beams are most commonly delivered using segmental multileaf collimation, although an increasing number of radiation therapy departments are employing dynamic multileaf collimation. The irradiation time using dynamic multileaf collimation depends strongly on the nature of the desired dose distribution, and it is difficult to reduce this time to less than the sum of the irradiation times for all individual peak heights using dynamic leaf collimation [Svensson et al., Phys. Med. Biol. 39, 37-61 (1994)]. Therefore, the intensity modulation will considerably increase the total treatment time. A more cost-effective procedure for rapid intensity modulation is using narrow scanned photon, electron, and light ion beams in combination with fast multileaf collimator penumbra trimming. With this approach, the irradiation time is largely independent of the complexity of the desired intensity distribution and, in the case of photon beams, may even be shorter than with uniform beams. The intensity modulation is achieved primarily by scanning of a narrow elementary photon pencil beam generated by directing a narrow well focused high energy electron beam onto a thin bremsstrahlung target. In the present study, the design of a fast low-weight multileaf collimator that is capable of further sharpening the penumbra at the edge of the elementary scanned beam has been simulated, in order to minimize the dose or radiation response of healthy tissues. In the case of photon beams, such a multileaf collimator can be placed relatively close to the bremsstrahlung target to minimize its size. It can also be flat and thin, i.e., only 15-25 mm thick in the direction of the beam with edges made of tungsten or preferably osmium to optimize the sharpening of the penumbra. The low height of the collimator will minimize edge scatter from glancing incidence. The major portions of the collimator leafs can then be made of steel or even aluminum, so that the total weight of the multileaf collimator will be as low as 10 kg, which may even allow high-speed collimation in real time in synchrony with organ movements. To demonstrate the efficiency of this collimator design in combination with pencil beam scanning, optimal radiobiological treatments of an advanced cervix cancer were simulated. Different geometrical collimator designs were tested for bremsstrahlung, electron, and light ion beams. With a 10 mm half-width elementary scanned photon beam and a steel collimator with tungsten edges, it was possible to make as effective treatments as obtained with intensity modulated beams of full resolution, i.e., here 5 mm resolution in the fluence map. In combination with narrow pencil beam scanning, such a collimator may provide ideal delivery of photons, electrons, or light ions for radiation therapy synchronized to breathing and other organ motions. These high-energy photon and light ion beams may allow three-dimensional in vivo verification of delivery and thereby clinical implementation of the BioArt approach using Biologically Optimized three-dimensional in vivo predictive Assay based adaptive Radiation Therapy [Brahme, Acta Oncol. 42, 123-126 (2003)].

  8. Feasibility study on low-dosage digital tomosynthesis (DTS) using a multislit collimation technique

    NASA Astrophysics Data System (ADS)

    Park, S. Y.; Kim, G. A.; Park, C. K.; Cho, H. S.; Seo, C. W.; Lee, D. Y.; Kang, S. Y.; Kim, K. S.; Lim, H. W.; Lee, H. W.; Park, J. E.; Kim, W. S.; Jeon, D. H.; Woo, T. H.

    2018-04-01

    In this study, we investigated an effective low-dose digital tomosynthesis (DTS) where a multislit collimator placed between the X-ray tube and the patient oscillates during projection data acquisition, partially blocking the X-ray beam to the patient thereby reducing the radiation dosage. We performed a simulation using the proposed DTS with two sets of multislit collimators both having a 50% duty cycle and investigated the image characteristics to demonstrate the feasibility of this proposed approach. In the simulation, all projections were taken at a tomographic angle of θ = ± 50° and an angle step of Δθ =2°. We utilized an iterative algorithm based on a compressed-sensing (CS) scheme for more accurate DTS reconstruction. Using the proposed DTS, we successfully obtained CS-reconstructed DTS images with no bright-band artifacts around the multislit edges of the collimator, thus maintaining the image quality. Therefore, the use of multislit collimation in current real-world DTS systems can reduce the radiation dosage to patients.

  9. Experiments with crystal deflectors for high energy ion beams: Electromagnetic dissociation probability for well channeled ions

    NASA Astrophysics Data System (ADS)

    Scandale, W.; Taratin, A. M.; Kovalenko, A. D.

    2013-01-01

    The paper presents the current status with the use of the crystal defectors for high energy ion beams. The channeling properties of multicharged ions are discussed. The results of the experiments on the deflection and extraction (collimation) of high energy ion beams with bent crystals performed in the accelerator centers are shortly considered. The analysis of the recent collimation experiment with a Pb nuclei of 270GeV/c per charge at the CERN Super Proton Synchrotron showed that the channeling efficiency was as large as about 90%. For Pb ions of the LHC energies a new mechanism, which can reduce the channeling efficiency, appears. The electromagnetic dissociation (ED) becomes possible for well channeled particles. However, the estimations performed in the paper show that the ED probability is small and should not visibly reduce the collimation efficiency. On the other hand, the aligned crystal gives the possibility to study the ED processes of heavy nuclei in the conditions when nuclear interactions are fully suppressed.

  10. Detector, collimator and real-time reconstructor for a new scanning-beam digital x-ray (SBDX) prototype.

    PubMed

    Speidel, Michael A; Tomkowiak, Michael T; Raval, Amish N; Dunkerley, David A P; Slagowski, Jordan M; Kahn, Paul; Ku, Jamie; Funk, Tobias

    Scanning-beam digital x-ray (SBDX) is an inverse geometry fluoroscopy system for low dose cardiac imaging. The use of a narrow scanned x-ray beam in SBDX reduces detected x-ray scatter and improves dose efficiency, however the tight beam collimation also limits the maximum achievable x-ray fluence. To increase the fluence available for imaging, we have constructed a new SBDX prototype with a wider x-ray beam, larger-area detector, and new real-time image reconstructor. Imaging is performed with a scanning source that generates 40,328 narrow overlapping projections from 71 × 71 focal spot positions for every 1/15 s scan period. A high speed 2-mm thick CdTe photon counting detector was constructed with 320×160 elements and 10.6 cm × 5.3 cm area (full readout every 1.28 μs), providing an 86% increase in area over the previous SBDX prototype. A matching multihole collimator was fabricated from layers of tungsten, brass, and lead, and a multi-GPU reconstructor was assembled to reconstruct the stream of captured detector images into full field-of-view images in real time. Thirty-two tomosynthetic planes spaced by 5 mm plus a multiplane composite image are produced for each scan frame. Noise equivalent quanta on the new SBDX prototype measured 63%-71% higher than the previous prototype. X-ray scatter fraction was 3.9-7.8% when imaging 23.3-32.6 cm acrylic phantoms, versus 2.3-4.2% with the previous prototype. Coronary angiographic imaging at 15 frame/s was successfully performed on the new SBDX prototype, with live display of either a multiplane composite or single plane image.

  11. Successive approximation algorithm for beam-position-monitor-based LHC collimator alignment

    NASA Astrophysics Data System (ADS)

    Valentino, Gianluca; Nosych, Andriy A.; Bruce, Roderik; Gasior, Marek; Mirarchi, Daniele; Redaelli, Stefano; Salvachua, Belen; Wollmann, Daniel

    2014-02-01

    Collimators with embedded beam position monitor (BPM) button electrodes will be installed in the Large Hadron Collider (LHC) during the current long shutdown period. For the subsequent operation, BPMs will allow the collimator jaws to be kept centered around the beam orbit. In this manner, a better beam cleaning efficiency and machine protection can be provided at unprecedented higher beam energies and intensities. A collimator alignment algorithm is proposed to center the jaws automatically around the beam. The algorithm is based on successive approximation and takes into account a correction of the nonlinear BPM sensitivity to beam displacement and an asymmetry of the electronic channels processing the BPM electrode signals. A software implementation was tested with a prototype collimator in the Super Proton Synchrotron. This paper presents results of the tests along with some considerations for eventual operation in the LHC.

  12. SU-E-I-42: Measurement of X-Ray Beam Width and Geometric Efficiency in MDCT Using Radiochromic Films.

    PubMed

    Liillau, T; Liebmann, M; von Boetticher, H; Poppe, B

    2012-06-01

    The purpose of this work was to measure the x-ray beam width and geometric efficiency (GE) of a multi detector computed tomography scanner (MDCT) for different beam collimations using radiochromic films. In MDCT, the primary beam width extends the nominal beam collimation to irradiate the active detector elements uniformly (called 'over-beaming') which contributes to increased radiation dose to the patient compared to single detector CT. Therefore, the precise determination of the primary beam width and GE is of value for any CT dose calculation using Monte Carlo or analytical methods. Single axial dose profiles free in air were measured for 6 different beam collimations nT for a Siemens SOMATOM Sensation 64 Scanner with Gafchromic XR-QA2 films. The films were calibrated relative to the measured charge of a PTW semiflex ionization chamber (type: 31010) for a single rotation in the CT scanner at the largest available beam collimation of 28.8 mm. The beam energy for all measurements in this work was set to 120 kVp. For every measured dose profile and beam collimation the GEin-air and the full-width-at-half- maximum value (FWHM) as a value for the x-ray beam width was determined. Over-beaming factors FWHM / nT were calculated accordingly. For MDCT beam collimations from 7.2 (12×0.6 mm) to 28.8 (24×1.2 mm) the geometric efficiency was between 58 and 85 %. The over- beaming factor ranged from 1.43 to 1.11. For beam collimations of 1×5 mm and 1×10 mm the GE was 77 % and 84 % respectively. The over-beaming factors were close to 1, as expected. This work has shown that radiochromic films can be used for accurate x-ray beam width and geometric efficiency measurements due to their high spatial resolution. The measured free-in-air geometric efficiency and the over-beaming factor depend strongly on beam collimation. © 2012 American Association of Physicists in Medicine.

  13. Collimation study for LCLS

    DOE PAGES

    Marin, E.; Raubenhaimer, T.; Welch, J.; ...

    2017-06-13

    In this study we investigate the power deposition along the undulator section of the SLAC Linac Coherent Light Source (LCLS) due to the primary e¯ -beam but also due to potential secondary particles. The expected beam distribution after the LCLS injector is deliberately broadened as an approximated representation of the beam halo. Secondary particles, as e +, e¯ and photons, are generated as a result of tracking the intercepted beam through a dense material. This process is carried out by means of GEANT-4, which has been convoluted into our main tracking engine, LUCRETIA. Simulations show no losses along the undulatormore » section when assuming the nominal primary beam and collimator gaps. However when opening the gaps of collimators located at the first collimator section, by 25%, the fattened beam is partially intercepted by the second collimator section, which is aligned to the undulators. Secondary particles, mostly photons generated at the second collimator section, deposit their energy along the undulator section, at a rate of the order of a milliwatt.« less

  14. Collimation study for LCLS

    NASA Astrophysics Data System (ADS)

    Marin, E.; Raubenhaimer, T.; Welch, J.; White, G.

    2017-09-01

    In this paper we investigate the power deposition along the undulator section of the SLAC Linac Coherent Light Source (LCLS) due to the primary e--beam but also due to potential secondary particles. The expected beam distribution after the LCLS injector is deliberately broadened as an approximated representation of the beam halo. Secondary particles, as e+, e- and photons, are generated as a result of tracking the intercepted beam through a dense material. This process is carried out by means of GEANT-4, which has been convoluted into our main tracking engine, LUCRETIA. Simulations show no losses along the undulator section when assuming the nominal primary beam and collimator gaps. However when opening the gaps of collimators located at the first collimator section, by 25%, the fattened beam is partially intercepted by the second collimator section, which is aligned to the undulators. Secondary particles, mostly photons generated at the second collimator section, deposit their energy along the undulator section, at a rate of the order of a milliwatt.

  15. The design of the new LHC connection cryostats

    NASA Astrophysics Data System (ADS)

    Vande Craen, A.; Barlow, G.; Eymin, C.; Moretti, M.; Parma, V.; Ramos, D.

    2017-12-01

    In the frame of the High Luminosity upgrade of the LHC, improved collimation schemes are needed to cope with the superconducting magnet quench limitations due to the increasing beam intensities and particle debris produced in the collision points. Two new TCLD collimators have to be installed on either side of the ALICE experiment to intercept heavy-ion particle debris. Beam optics solutions were found to place these collimators in the continuous cryostat of the machine, in the locations where connection cryostats, bridging a gap of about 13 m between adjacent magnets, are already present. It is therefore planned to replace these connection cryostats with two new shorter ones separated by a bypass cryostat allowing the collimators to be placed close to the beam pipes. The connection cryostats, of a new design when compared to the existing ones, will still have to ensure the continuity of the technical systems of the machine cryostat (i.e. beam lines, cryogenic and electrical circuits, insulation vacuum). This paper describes the functionalities and the design solutions implemented, as well as the plans for their construction.

  16. Sci—Thur PM: Planning and Delivery — 03: Automated delivery and quality assurance of a modulated electron radiation therapy plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Connell, T; Papaconstadopoulos, P; Alexander, A

    2014-08-15

    Modulated electron radiation therapy (MERT) offers the potential to improve healthy tissue sparing through increased dose conformity. Challenges remain, however, in accurate beamlet dose calculation, plan optimization, collimation method and delivery accuracy. In this work, we investigate the accuracy and efficiency of an end-to-end MERT plan and automated-delivery workflow for the electron boost portion of a previously treated whole breast irradiation case. Dose calculations were performed using Monte Carlo methods and beam weights were determined using a research-based treatment planning system capable of inverse optimization. The plan was delivered to radiochromic film placed in a water equivalent phantom for verification,more » using an automated motorized tertiary collimator. The automated delivery, which covered 4 electron energies, 196 subfields and 6183 total MU was completed in 25.8 minutes, including 6.2 minutes of beam-on time with the remainder of the delivery time spent on collimator leaf motion and the automated interfacing with the accelerator in service mode. The delivery time could be reduced by 5.3 minutes with minor electron collimator modifications and the beam-on time could be reduced by and estimated factor of 2–3 through redesign of the scattering foils. Comparison of the planned and delivered film dose gave 3%/3 mm gamma pass rates of 62.1, 99.8, 97.8, 98.3, and 98.7 percent for the 9, 12, 16, 20 MeV, and combined energy deliveries respectively. Good results were also seen in the delivery verification performed with a MapCHECK 2 device. The results showed that accurate and efficient MERT delivery is possible with current technologies.« less

  17. Novel adaptive fiber-optics collimator for coherent beam combination.

    PubMed

    Zhi, Dong; Ma, Pengfei; Ma, Yanxing; Wang, Xiaolin; Zhou, Pu; Si, Lei

    2014-12-15

    In this manuscript, we experimentally validate a novel design of adaptive fiber-optics collimator (AFOC), which utilizes two levers to enlarge the movable range of the fiber end cap. The enlargement of the range makes the new AFOC possible to compensate the end-cap/tilt aberration in fiber laser beam combining system. The new AFOC based on flexible hinges and levers was fabricated and the performance of the new AFOC was tested carefully, including its control range, frequency response and control accuracy. Coherent beam combination (CBC) of two 5-W fiber amplifiers array with simultaneously end-cap/tilt control and phase-locking control was implemented successfully with the novel AFOC. Experimental results show that the average normalized power in the bucket (PIB) value increases from 0.311 to 0.934 with active phasing and tilt aberration compensation simultaneously, and with both controls on, the fringe contrast improves to more than 82% from 0% for the case with both control off. This work presents a promising structure for tilt aberration control in high power CBC system.

  18. Method and apparatus for a multibeam beacon laser assembly for optical communications

    NASA Technical Reports Server (NTRS)

    Biswas, Abhijit (Inventor); Sanji, Babak (Inventor); Wright, Malcolm W. (Inventor); Page, Norman Alan (Inventor)

    2005-01-01

    An optical beacon is comprised of a telescope having a primary focal plane or Coud? focal plane, a plurality of fiber coupled laser sources for generating a plurality of beams, a collimator for collimating the plurality of beams, and optics for combining and focusing the plurality of collimated beams onto the primary or Coud? focal plane of the telescope. The telescope propagates the optical beacon, which is arranged into a ring of incoherent plurality of collimated beams. The apparatus further comprises fiber splitters coupled to each laser source to provide at least eight beams from at least four laser sources. The optics comprises a prism assembly, a combiner lens, a focusing lens and a field lens for focusing the plurality of collimated beams onto the primary focal plane or Coud? focal plane of the telescope.

  19. A dynamic collimation system for penumbra reduction in spot-scanning proton therapy: Proof of concept

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hyer, Daniel E., E-mail: daniel-hyer@uiowa.edu; Hill, Patrick M.; Wang, Dongxu

    2014-09-15

    Purpose: In the absence of a collimation system the lateral penumbra of spot scanning (SS) dose distributions delivered by low energy proton beams is highly dependent on the spot size. For current commercial equipment, spot size increases with decreasing proton energy thereby reducing the benefit of the SS technique. This paper presents a dynamic collimation system (DCS) for sharpening the lateral penumbra of proton therapy dose distributions delivered by SS. Methods: The collimation system presented here exploits the property that a proton pencil beam used for SS requires collimation only when it is near the target edge, enabling the usemore » of trimmers that are in motion at times when the pencil beam is away from the target edge. The device consists of two pairs of parallel nickel trimmer blades of 2 cm thickness and dimensions of 2 cm × 18 cm in the beam's eye view. The two pairs of trimmer blades are rotated 90° relative to each other to form a rectangular shape. Each trimmer blade is capable of rapid motion in the direction perpendicular to the central beam axis by means of a linear motor, with maximum velocity and acceleration of 2.5 m/s and 19.6 m/s{sup 2}, respectively. The blades travel on curved tracks to match the divergence of the proton source. An algorithm for selecting blade positions is developed to minimize the dose delivered outside of the target, and treatment plans are created both with and without the DCS. Results: The snout of the DCS has outer dimensions of 22.6 × 22.6 cm{sup 2} and is capable of delivering a minimum treatment field size of 15 × 15 cm{sup 2}. Using currently available components, the constructed system would weigh less than 20 kg. For irregularly shaped fields, the use of the DCS reduces the mean dose outside of a 2D target of 46.6 cm{sup 2} by approximately 40% as compared to an identical plan without collimation. The use of the DCS increased treatment time by 1–3 s per energy layer. Conclusions: The spread of the lateral penumbra of low-energy SS proton treatments may be greatly reduced with the use of this system at the cost of only a small penalty in delivery time.« less

  20. Simulations and measurements of beam loss patterns at the CERN Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Bruce, R.; Assmann, R. W.; Boccone, V.; Bracco, C.; Brugger, M.; Cauchi, M.; Cerutti, F.; Deboy, D.; Ferrari, A.; Lari, L.; Marsili, A.; Mereghetti, A.; Mirarchi, D.; Quaranta, E.; Redaelli, S.; Robert-Demolaize, G.; Rossi, A.; Salvachua, B.; Skordis, E.; Tambasco, C.; Valentino, G.; Weiler, T.; Vlachoudis, V.; Wollmann, D.

    2014-08-01

    The CERN Large Hadron Collider (LHC) is designed to collide proton beams of unprecedented energy, in order to extend the frontiers of high-energy particle physics. During the first very successful running period in 2010-2013, the LHC was routinely storing protons at 3.5-4 TeV with a total beam energy of up to 146 MJ, and even higher stored energies are foreseen in the future. This puts extraordinary demands on the control of beam losses. An uncontrolled loss of even a tiny fraction of the beam could cause a superconducting magnet to undergo a transition into a normal-conducting state, or in the worst case cause material damage. Hence a multistage collimation system has been installed in order to safely intercept high-amplitude beam protons before they are lost elsewhere. To guarantee adequate protection from the collimators, a detailed theoretical understanding is needed. This article presents results of numerical simulations of the distribution of beam losses around the LHC that have leaked out of the collimation system. The studies include tracking of protons through the fields of more than 5000 magnets in the 27 km LHC ring over hundreds of revolutions, and Monte Carlo simulations of particle-matter interactions both in collimators and machine elements being hit by escaping particles. The simulation results agree typically within a factor 2 with measurements of beam loss distributions from the previous LHC run. Considering the complex simulation, which must account for a very large number of unknown imperfections, and in view of the total losses around the ring spanning over 7 orders of magnitude, we consider this an excellent agreement. Our results give confidence in the simulation tools, which are used also for the design of future accelerators.

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Igarashi, Noriyuki, E-mail: noriyuki.igarashi@kek.jp; Nitani, Hiroaki; Takeichi, Yasuo

    BL-15A is a new x-ray undulator beamline at the Photon Factory. It will be dedicated to two independent research activities, simultaneous XAFS/XRF/XRD experiments, and SAXS/WAXS/GI-SAXS studies. In order to supply a choice of micro-focus, low-divergence and collimated beams, a double surface bimorph mirror was recently developed. To achieve further mirror surface optimization, the pencil beam scanning method was applied for “in-situ” beam inspection and the Inverse Matrix method was used for determination of optimal voltages on the piezoelectric actuators. The corrected beam profiles at every focal spot gave good agreement with the theoretical values and the resultant beam performance ismore » promising for both techniques. Quick and stable switching between highly focused and intense collimated beams was established using this new mirror with the simple motorized stages.« less

  2. Research and development of a dedicated collimator for 14.2 MeV fast neutrons for imaging using a D-T generator

    NASA Astrophysics Data System (ADS)

    Sabo-Napadensky, I.; Weiss-Babai, R.; Gayer, A.; Vartsky, D.; Bar, D.; Mor, I.; Chacham-Zada, R.; Cohen, M.; Tamim, N.

    2012-06-01

    One of the main problems in neutron imaging is the scattered radiation that accompanies the direct neutrons that reach the imaging detectors and affect the image quality. We have developed a dedicated collimator for 14.2 MeV fast neutrons. The collimator optimizes the amount of scattered radiation to primary neutrons that arrive at the imaging plane. We have used different materials within the collimator in order to lower the scattered radiation that arrives at the scanned object. The image quality and the signal to noise ratios that are measured show that a mixture of BORAX (Na2B4O7ṡ10H2O) and water in the experimental beam collimator give the best results. We have used GEANT4 to simulate the collimator performance, the simulations predict the optimized material looking on the ratios of the scattered to primary neutrons that contribute in the detector. We present our experimental setup, report the results of the experimental and related simulation studies with neutrons beam generated by a 14.2 MeV D-T neutron generator.

  3. Modified optical fiber daylighting system with sunlight transportation in free space.

    PubMed

    Vu, Ngoc-Hai; Pham, Thanh-Tuan; Shin, Seoyong

    2016-12-26

    We present the design, optical simulation, and experiment of a modified optical fiber daylighting system (M-OFDS) for indoor lighting. The M-OFDS is comprised of three sub-systems: concentration, collimation, and distribution. The concentration part is formed by coupling a Fresnel lens with a large-core plastic optical fiber. The sunlight collected by the concentration sub-system is propagated in a plastic optical fiber and then collimated by the collimator, which is a combination of a parabolic mirror and a convex lens. The collimated beam of sunlight travels in free space and is guided to the interior by directing flat mirrors, where it is diffused uniformly by a distributor. All parameters of the system are calculated theoretically. Based on the designed system, our simulation results demonstrated a maximum optical efficiency of 71%. The simulation results also showed that sunlight could be delivered to the illumination destination at distance of 30 m. A prototype of the M-OFDS was fabricated, and preliminary experiments were performed outdoors. The simulation results and experimental results confirmed that the M-OFDS was designed effectively. A large-scale system constructed by several M-OFDSs is also proposed. The results showed that the presented optical fiber daylighting system is a strong candidate for an inexpensive and highly efficient application of solar energy in buildings.

  4. Holographic Waveguide Array Rollable Display.

    DTIC Science & Technology

    1997-04-01

    scale lithography for fabrication. Projection systems offer large images, in the range of 40 - 60 inches diagonal, and both front-view and rear-view...Boulder, CO, and a l-D array of digital micromirrors ( DMD ) from Texas Instruments. The linear format permits simple driving electronics and high...TI’s DMD , or a CMOS-SLM. A collimated laser beaming (combine three colors) or a collimated white light beam from a high intensity halogen lamp can be

  5. Matching of electron beams for conformal therapy of target volumes at moderate depths.

    PubMed

    Zackrisson, B; Karlsson, M

    1996-06-01

    The basic requirements for conformal electron therapy are an accelerator with a wide range of energies and field shapes. The beams should be well characterised in a full 3-D dose planning system which has been verified for the geometries of the current application. Differences in the basic design of treatment units have been shown to have a large influence on beam quality and dosimetry. Modern equipment can deliver electron beams of good quality with a high degree of accuracy. A race-track microtron with minimised electron scattering and a multi-leaf collimator (MLC) for electron collimating will facilitate the isocentric technique as a general treatment technique for electrons. This will improve the possibility of performing combined electron field techniques in order to conform the dose distribution with no or minimal use of a bolus. Furthermore, the isocentric technique will facilitate multiple field arrangements that decrease the problems with distortion of the dose distribution due to inhomogeneities, etc. These situations are demonstrated by clinical examples where isocentric, matched electron fields for treatment of the nose, thyroid and thoracic wall have been used.

  6. Machine-related backgrounds in the SiD detector at ILC

    NASA Astrophysics Data System (ADS)

    Denisov, D. S.; Mokhov, N. V.; Striganov, S. I.; Kostin, M. A.; Tropin, I. S.

    2006-12-01

    With a multi-stage collimation system and magnetic iron spoilers in the tunnel, the background particle fluxes on the ILC detector can be substantially reduced. At the same time, beam-halo interactions with collimators and protective masks in the beam delivery system create fluxes of muons and other secondary particles which can still exceed the tolerable levels for some of the ILC sub-detectors. Results of modeling of such backgrounds in comparison to those from the e+e- interactions are presented in this paper for the SiD detector.

  7. SU-E-T-187: Collimation Methods in Spot Scanning Proton Therapy: A Treatment Plan Comparison Between a Fixed Aperture and a Dynamic Collimation System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, B; Gelover, E; Wang, D

    2015-06-15

    Purpose: Low-energy treatments during spot scanning proton therapy (SSPT) suffer from poor conformity due to increased spot size. Collimation devices can reduce the lateral penumbra of a proton therapy dose distribution and improve the overall plan quality. The purpose of this work was to study the advantages of individual energy-layer collimation, which is unique to a recently proposed Dynamic Collimation System (DCS), in comparison to a standard, fixed aperture that allows only a single shape for all energy layers. Methods: Three brain patients previously planned and treated with SSPT were re-planned using an in-house treatment planning system capable of modelingmore » collimated and un-collimated proton beamlets. The un-collimated plans, which served as a baseline for comparison, reproduced the target coverage of the clinically delivered plans. The collimator opening for the aperture based plans included a 0.6 cm expansion of the largest cross section of the target in the Beam’s Eye View, while the DCS based plans were created by optimizing the collimator position for beam spots near the periphery of the target in each energy layer. Results: The reduction of mean dose to normal tissue adjacent to the target, as defined by a 10 mm ring, averaged 9.13% and 3.48% for the DCS and aperture plans, respectively. The conformity index, as defined by the ratio of the volume of the 50% isodose line to the target volume, yielded an average improvement of 16.42% and 8.16% for the DCS and aperture plans, respectively. Conclusion: Collimation reduces the dose to normal tissue adjacent to the target and increases dose conformity to the target region for low-energy SSPT. The ability of the DCS to provide collimation to each energy layer yields better conformity in comparison to fixed aperture plans. This work was partially funded by IBA (Ion Beam Applications S.A.)« less

  8. Hollow Electron Beam Collimation for HL-LHC - Effects on the Beam Core

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fitterer, M.; Stancari, G.; Valishev, A.

    2017-06-13

    Collimation with hollow electron beams is currently one of the most promising concepts for active halo control in the High Luminosity Large Hadron Collider (HL-LHC). To ensure the successful operation of the hollow beam collimator the unwanted effects on the beam core, which might arise from the operation with a pulsed electron beam, must be minimized. This paper gives a summary of the effect of hollow electron lenses on the beam core in terms of sources, provides estimates for HL-LHC and discusses the possible mitigation methods.

  9. Transmission calculation and intensity suppression for a proton therapy system

    NASA Astrophysics Data System (ADS)

    Chen, Wei; Yang, Jun; Qin, Bin; Liang, ZhiKai; Chen, Qushan; Liu, Kaifeng; Li, Dong; Fan, Mingwu

    2018-02-01

    A proton therapy project HUST-PTF (HUST Proton Therapy Facility) based on a 250 MeV isochronous superconducting cyclotron is under development in Huazhong University of Science and Technology (HUST). In this paper we report the main design features of the beam line in HUST-PTF project. The energy selection system (ESS) for energy modulation is discussed in detail, including the collimators, momentum slit and transmission calculation. Due to significant difference among the transmissions of ESS for different energies, the intensity suppression scheme by defocusing beam at high energies on collimators in the beam line is proposed and discussed. Finally, the ratios of beam intensities between low and high energies are expected to be controlled within 10 to meet the clinical requirement, and the beam optics of each energy step after intensity suppression is studied respectively.

  10. Variability of surface and center position radiation dose in MDCT: Monte Carlo simulations using CTDI and anthropomorphic phantoms

    PubMed Central

    Zhang, Di; Savandi, Ali S.; Demarco, John J.; Cagnon, Chris H.; Angel, Erin; Turner, Adam C.; Cody, Dianna D.; Stevens, Donna M.; Primak, Andrew N.; McCollough, Cynthia H.; McNitt-Gray, Michael F.

    2009-01-01

    The larger coverage afforded by wider z-axis beams in multidetector CT (MDCT) creates larger cone angles and greater beam divergence, which results in substantial surface dose variation for helical and contiguous axial scans. This study evaluates the variation of absorbed radiation dose in both cylindrical and anthropomorphic phantoms when performing helical or contiguous axial scans. The approach used here was to perform Monte Carlo simulations of a 64 slice MDCT. Simulations were performed with different radiation profiles (simulated beam widths) for a given collimation setting (nominal beam width) and for different pitch values and tube start angles. The magnitude of variation at the surface was evaluated under four different conditions: (a) a homogeneous CTDI phantom with different combinations of pitch and simulated beam widths, (b) a heterogeneous anthropomorphic phantom with one measured beam collimation and various pitch values, (c) a homogeneous CTDI phantom with fixed beam collimation and pitch, but with different tube start angles, and (d) pitch values that should minimize variations of surface dose—evaluated for both homogeneous and heterogeneous phantoms. For the CTDI phantom simulations, peripheral dose patterns showed variation with percent ripple as high as 65% when pitch is 1.5 and simulated beam width is equal to the nominal collimation. For the anterior surface dose on an anthropomorphic phantom, the percent ripple was as high as 40% when the pitch is 1.5 and simulated beam width is equal to the measured beam width. Low pitch values were shown to cause beam overlaps which created new peaks. Different x-ray tube start angles create shifts of the peripheral dose profiles. The start angle simulations showed that for a given table position, the surface dose could vary dramatically with minimum values that were 40% of the peak when all conditions are held constant except for the start angle. The last group of simulations showed that an “ideal” pitch value can be determined which reduces surface dose variations, but this pitch value must take into account the measured beam width. These results reveal the complexity of estimating surface dose and demonstrate a range of dose variability at surface positions for both homogeneous cylindrical and heterogeneous anthropomorphic phantoms. These findings have potential implications for small-sized dosimeter measurements in phantoms, such as with TLDs or small Farmer chambers. PMID:19378763

  11. Dosimetric effect of limited aperture multileaf collimator on VMAT plan quality: A study of prostate and head-and-neck cancers.

    PubMed

    Murtaza, Ghulam; Mehmood, Shahid; Rasul, Shahid; Murtaza, Imran; Khan, Ehsan Ullah

    2018-01-01

    The aim of study was to evaluate the dosimetric effect of collimator-rotation on VMAT plan quality, when using limited aperture multileaf collimator of Elekta Beam Modulator™ providing a maximum aperture of 21 cm × 16 cm. The increased use of VMAT technique to deliver IMRT from conventional to very specialized treatments present a challenge in plan optimization. In this study VMAT plans were optimized for prostate and head and neck cancers using Elekta Beam-Modulator TM , whereas previous studies were reported for conventional Linac aperture. VMAT plans for nine of each prostate and head-and-neck cancer patients were produced using the 6 MV photon beam for Elekta-SynergyS ® Linac using Pinnacle 3 treatment planning system. Single arc, dual arc and two combined independent-single arcs were optimized for collimator angles (C) 0°, 90° and 0°-90° (0°-90°; i.e. the first-arc was assigned C0° and second-arc was assigned C90°). A treatment plan comparison was performed among C0°, C90° and C(0°-90°) for single-arc dual-arc and two independent-single-arcs VMAT techniques to evaluate the influence of extreme collimator rotations (C0° and 90°) on VMAT plan quality. Plan evaluation criteria included the target coverage, conformity index, homogeneity index and doses to organs at risk. A 'two-sided student t -test' ( p  ≤ 0.05) was used to determine if there was a significant difference in dose volume indices of plans. For both prostate and head-and-neck, plan quality at collimator angles C0° and C(0°-90°) was clinically acceptable for all VMAT-techniques, except SA for head-and-neck. Poorer target coverage, higher normal tissue doses and significant p -values were observed for collimator angle 90° when compared with C0° and C(0°-90°). A collimator rotation of 0° provided significantly better target coverage and sparing of organs-at-risk than a collimator rotation of 90° for all VMAT techniques.

  12. Influence of beam efficiency through the patient-specific collimator on secondary neutron dose equivalent in double scattering and uniform scanning modes of proton therapy.

    PubMed

    Hecksel, D; Anferov, V; Fitzek, M; Shahnazi, K

    2010-06-01

    Conventional proton therapy facilities use double scattering nozzles, which are optimized for delivery of a few fixed field sizes. Similarly, uniform scanning nozzles are commissioned for a limited number of field sizes. However, cases invariably occur where the treatment field is significantly different from these fixed field sizes. The purpose of this work was to determine the impact of the radiation field conformity to the patient-specific collimator on the secondary neutron dose equivalent. Using a WENDI-II neutron detector, the authors experimentally investigated how the neutron dose equivalent at a particular point of interest varied with different collimator sizes, while the beam spreading was kept constant. The measurements were performed for different modes of dose delivery in proton therapy, all of which are available at the Midwest Proton Radiotherapy Institute (MPRI): Double scattering, uniform scanning delivering rectangular fields, and uniform scanning delivering circular fields. The authors also studied how the neutron dose equivalent changes when one changes the amplitudes of the scanned field for a fixed collimator size. The secondary neutron dose equivalent was found to decrease linearly with the collimator area for all methods of dose delivery. The relative values of the neutron dose equivalent for a collimator with a 5 cm diameter opening using 88 MeV protons were 1.0 for the double scattering field, 0.76 for rectangular uniform field, and 0.6 for the circular uniform field. Furthermore, when a single circle wobbling was optimized for delivery of a uniform field 5 cm in diameter, the secondary neutron dose equivalent was reduced by a factor of 6 compared to the double scattering nozzle. Additionally, when the collimator size was kept constant, the neutron dose equivalent at the given point of interest increased linearly with the area of the scanned proton beam. The results of these experiments suggest that the patient-specific collimator is a significant contributor to the secondary neutron dose equivalent to a distant organ at risk. Improving conformity of the radiation field to the patient-specific collimator can significantly reduce secondary neutron dose equivalent to the patient. Therefore, it is important to increase the number of available generic field sizes in double scattering systems as well as in uniform scanning nozzles.

  13. Full-field fan-beam x-ray fluorescence computed tomography system design with linear-array detectors and pinhole collimation: a rapid Monte Carlo study

    NASA Astrophysics Data System (ADS)

    Zhang, Siyuan; Li, Liang; Li, Ruizhe; Chen, Zhiqiang

    2017-11-01

    We present the design concept and initial simulations for a polychromatic full-field fan-beam x-ray fluorescence computed tomography (XFCT) device with pinhole collimators and linear-array photon counting detectors. The phantom is irradiated by a fan-beam polychromatic x-ray source filtered by copper. Fluorescent photons are stimulated and then collected by two linear-array photon counting detectors with pinhole collimators. The Compton scatter correction and the attenuation correction are applied in the data processing, and the maximum-likelihood expectation maximization algorithm is applied for the image reconstruction of XFCT. The physical modeling of the XFCT imaging system was described, and a set of rapid Monte Carlo simulations was carried out to examine the feasibility and sensitivity of the XFCT system. Different concentrations of gadolinium (Gd) and gold (Au) solutions were used as contrast agents in simulations. Results show that 0.04% of Gd and 0.065% of Au can be well reconstructed with the full scan time set at 6 min. Compared with using the XFCT system with a pencil-beam source or a single-pixel detector, using a full-field fan-beam XFCT device with linear-array detectors results in significant scanning time reduction and may satisfy requirements of rapid imaging, such as in vivo imaging experiments.

  14. Scanning optical microscope with long working distance objective

    DOEpatents

    Cloutier, Sylvain G.

    2010-10-19

    A scanning optical microscope, including: a light source to generate a beam of probe light; collimation optics to substantially collimate the probe beam; a probe-result beamsplitter; a long working-distance, infinity-corrected objective; scanning means to scan a beam spot of the focused probe beam on or within a sample; relay optics; and a detector. The collimation optics are disposed in the probe beam. The probe-result beamsplitter is arranged in the optical paths of the probe beam and the resultant light from the sample. The beamsplitter reflects the probe beam into the objective and transmits resultant light. The long working-distance, infinity-corrected objective is also arranged in the optical paths of the probe beam and the resultant light. It focuses the reflected probe beam onto the sample, and collects and substantially collimates the resultant light. The relay optics are arranged to relay the transmitted resultant light from the beamsplitter to the detector.

  15. ABORT GAP CLEANING IN RHIC.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DREES,A.; AHRENS,L.; III FLILLER,R.

    2002-06-03

    During the RHIC Au-run in 2001 the 200 MHz storage cavity system was used for the first time. The rebucketing procedure caused significant beam debunching in addition to amplifying debunching due to other mechanisms. At the end of a four hour store, debunched beam could account for approximately 30%-40% of the total beam intensity. Some of it will be in the abort gap. In order to minimize the risk of magnet quenching due to uncontrolled beam losses at the time of a beam dump, a combination of a fast transverse kicker and copper collimators were used to clean the abortmore » gap. This report gives an overview of the gap cleaning procedure and the achieved performance.« less

  16. Efficient dielectric metasurface collimating lenses for mid-infrared quantum cascade lasers.

    PubMed

    Arbabi, Amir; Briggs, Ryan M; Horie, Yu; Bagheri, Mahmood; Faraon, Andrei

    2015-12-28

    Light emitted from single-mode semiconductor lasers generally has large divergence angles, and high numerical aperture lenses are required for beam collimation. Visible and near infrared lasers are collimated using aspheric glass or plastic lenses, yet collimation of mid-infrared quantum cascade lasers typically requires more costly aspheric lenses made of germanium, chalcogenide compounds, or other infrared-transparent materials. Here we report mid-infrared dielectric metasurface flat lenses that efficiently collimate the output beam of single-mode quantum cascade lasers. The metasurface lenses are composed of amorphous silicon posts on a flat sapphire substrate and can be fabricated at low cost using a single step conventional UV binary lithography. Mid-infrared radiation from a 4.8 μm distributed-feedback quantum cascade laser is collimated using a polarization insensitive metasurface lens with 0.86 numerical aperture and 79% transmission efficiency. The collimated beam has a half divergence angle of 0.36° and beam quality factor of M2=1.02.

  17. Efficient dielectric metasurface collimating lenses for mid-infrared quantum cascade lasers

    DOE PAGES

    Arbabi, Amir; Briggs, Ryan M.; Horie, Yu; ...

    2015-01-01

    Light emitted from single-mode semiconductor lasers generally has large divergence angles, and high numerical aperture lenses are required for beam collimation. Visible and near infrared lasers are collimated using aspheric glass or plastic lenses, yet collimation of mid-infrared quantum cascade lasers typically requires more costly aspheric lenses made of germanium, chalcogenide compounds, or other infrared-transparent materials. We report mid-infrared dielectric metasurface flat lenses that efficiently collimate the output beam of single-mode quantum cascade lasers. The metasurface lenses are composed of amorphous silicon posts on a flat sapphire substrate and can be fabricated at low cost using a single step conventionalmore » UV binary lithography. Mid-infrared radiation from a 4.8 μm distributed-feedback quantum cascade laser is collimated using a polarization insensitive metasurface lens with 0.86 numerical aperture and 79% transmission efficiency. The collimated beam has a half divergence angle of 0.36° and beam quality factor of M² =1.02.« less

  18. Effect of confining wall potential on charged collimated dust beam in low-pressure plasma

    NASA Astrophysics Data System (ADS)

    Kausik, S. S.; Kakati, B.; Saikia, B. K.

    2013-05-01

    The effect of confining wall potential on charged collimated dust beam in low-pressure plasma has been studied in a dusty plasma experimental setup by applying electrostatic field to each channel of a multicusp magnetic cage. Argon plasma is produced by hot cathode discharge method at a pressure of 5×10-4 millibars and is confined by a full line cusped magnetic field confinement system. Silver dust grains are produced by gas-evaporation technique and move upward in the form of a collimated dust beam due to differential pressure maintained between the dust and plasma chambers. The charged grains in the beam after coming out from the plasma column enter into the diagnostic chamber and are deflected by a dc field applied across a pair of deflector plates at different confining potentials. Both from the amount of deflection and the floating potential, the number of charges collected by the dust grains is calculated. Furthermore, the collimated dust beam strikes the Faraday cup, which is placed above the deflector plates, and the current (˜pA) so produced is measured by an electrometer at different confining potentials. The experimental results demonstrate the significant effect of confining wall potential on charging of dust grains.

  19. A study of lateral fall-off (penumbra) optimisation for pencil beam scanning (PBS) proton therapy

    NASA Astrophysics Data System (ADS)

    Winterhalter, C.; Lomax, A.; Oxley, D.; Weber, D. C.; Safai, S.

    2018-01-01

    The lateral fall-off is crucial for sparing organs at risk in proton therapy. It is therefore of high importance to minimize the penumbra for pencil beam scanning (PBS). Three optimisation approaches are investigated: edge-collimated uniformly weighted spots (collimation), pencil beam optimisation of uncollimated pencil beams (edge-enhancement) and the optimisation of edge collimated pencil beams (collimated edge-enhancement). To deliver energies below 70 MeV, these strategies are evaluated in combination with the following pre-absorber methods: field specific fixed thickness pre-absorption (fixed), range specific, fixed thickness pre-absorption (automatic) and range specific, variable thickness pre-absorption (variable). All techniques are evaluated by Monte Carlo simulated square fields in a water tank. For a typical air gap of 10 cm, without pre-absorber collimation reduces the penumbra only for water equivalent ranges between 4-11 cm by up to 2.2 mm. The sharpest lateral fall-off is achieved through collimated edge-enhancement, which lowers the penumbra down to 2.8 mm. When using a pre-absorber, the sharpest fall-offs are obtained when combining collimated edge-enhancement with a variable pre-absorber. For edge-enhancement and large air gaps, it is crucial to minimize the amount of material in the beam. For small air gaps however, the superior phase space of higher energetic beams can be employed when more material is used. In conclusion, collimated edge-enhancement combined with the variable pre-absorber is the recommended setting to minimize the lateral penumbra for PBS. Without collimator, it would be favourable to use a variable pre-absorber for large air gaps and an automatic pre-absorber for small air gaps.

  20. An investigation of accelerator head scatter and output factor in air.

    PubMed

    Ding, George X

    2004-09-01

    Our purpose in this study was to investigate whether the Monte Carlo simulation can accurately predict output factors in air. Secondary goals were to study the head scatter components and investigate the collimator exchange effect. The Monte Carlo code, BEAMnrc, was used in the study. Photon beams of 6 and 18 MV were from a Varian Clinac 2100EX accelerator and the measurements were performed using an ionization chamber in a mini-phantom. The Monte Carlo calculated in air output factors was within 1% of measured values. The simulation provided information of the origin and the magnitude of the collimator exchange effect. It was shown that the collimator backscatter to the beam monitor chamber played a significant role in the beam output factors. However the magnitude of the scattered dose contributions from the collimator at the isocenter is negligible. The maximum scattered dose contribution from the collimators was about 0.15% and 0.4% of the total dose at the isocenter for a 6 and 18 MV beam, respectively. The scattered dose contributions from the flattening filter at the isocenter were about 0.9-3% and 0.2-6% of the total dose for field sizes of 4x4 cm2-40x40 cm2 for the 6 and 18 MV beam, respectively. The study suggests that measurements of head scatter factors be done at large depth well beyond the depth of electron contamination. The insight information may have some implications for developing generalized empirical models to calculate the head scatter.

  1. Long range laser traversing system

    NASA Technical Reports Server (NTRS)

    Caudill, L. O. (Inventor)

    1974-01-01

    The relative azimuth bearing between first and second spaced terrestrial points which may be obscured from each other by intervening terrain is measured by placing at one of the points a laser source for projecting a collimated beam upwardly in the vertical plane. The collimated laser beam is detected at the second point by positioning the optical axis of a receiving instrument for the laser beam in such a manner that the beam intercepts the optical axis. In response to the optical axis intercepting the beam, the beam is deflected into two different ray paths by a beam splitter having an apex located on the optical axis. The energy in the ray paths is detected by separate photoresponsive elements that drive logic networks for proving indications of: (1) the optical axis intercepting the beam; (2) the beam being on the left of the optical axis and (3) the beam being on the right side of the optical axis.

  2. Fiber optic diffraction grating maker

    DOEpatents

    Deason, V.A.; Ward, M.B.

    1991-05-21

    A compact and portable diffraction grating maker is comprised of a laser beam, optical and fiber optics devices coupling the beam to one or more evanescent beam splitters, and collimating lenses or mirrors directing the split beam at an appropriate photosensitive material. The collimating optics, the output ends of the fiber optic coupler and the photosensitive plate holder are all mounted on an articulated framework so that the angle of intersection of the beams can be altered at will without disturbing the spatial filter, collimation or beam quality, and assuring that the beams will always intersect at the position of the plate. 4 figures.

  3. Fiber optic diffraction grating maker

    DOEpatents

    Deason, Vance A.; Ward, Michael B.

    1991-01-01

    A compact and portable diffraction grating maker comprised of a laser beam, optical and fiber optics devices coupling the beam to one or more evanescent beam splitters, and collimating lenses or mirrors directing the split beam at an appropriate photosensitive material. The collimating optics, the output ends of the fiber optic coupler and the photosensitive plate holder are all mounted on an articulated framework so that the angle of intersection of the beams can be altered at will without disturbing the spatial filter, collimation or beam quality, and assuring that the beams will always intersect at the position of the plate.

  4. Beam collimation and energy spectrum compression of laser-accelerated proton beams using solenoid field and RF cavity

    NASA Astrophysics Data System (ADS)

    Teng, J.; Gu, Y. Q.; Zhu, B.; Hong, W.; Zhao, Z. Q.; Zhou, W. M.; Cao, L. F.

    2013-11-01

    This paper presents a new method of laser produced proton beam collimation and spectrum compression using a combination of a solenoid field and a RF cavity. The solenoid collects laser-driven protons efficiently within an angle that is smaller than 12 degrees because it is mounted few millimeters from the target, and collimates protons with energies around 2.3 MeV. The collimated proton beam then passes through a RF cavity to allow compression of the spectrum. Particle-in-cell (PIC) simulations demonstrate the proton beam transport in the solenoid and RF electric fields. Excellent energy compression and collection efficiency of protons are presented. This method for proton beam optimization is suitable for high repetition-rate laser acceleration proton beams, which could be used as an injector for a conventional proton accelerator.

  5. BEAM TRANSPORT LINES FOR THE BSNS.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    WEI, J.

    2006-06-26

    This paper presents the design of two beam transport lines at the BSNS: one is the injection line from the Linac to the RCS and the other is the target line from the RCS to the target station. In the injection beam line, space charge effects, transverse halo collimation, momentum tail collimation and debunching are the main concerned topics. A new method of using triplet cells and stripping foils is used to collimate transverse halo. A long straight section is reserved for the future upgrading linac and debuncher. In the target beam line, large halo emittance, beam stability at themore » target due to kicker failures and beam jitters, shielding of back-scattering neutrons from the target are main concerned topics. Special bi-gap magnets will be used to reduce beam losses in the collimators in front of the target.« less

  6. Solar concentrator with integrated tracking and light delivery system with collimation

    DOEpatents

    Maxey, Lonnie Curt

    2015-06-09

    A solar light distribution system includes a solar light concentrator that is affixed externally to a light transfer tube. Solar light waves are processed by the concentrator into a collimated beam of light, which is then transferred through a light receiving port and into the light transfer tube. A reflector directs the collimated beam of light through the tube to a light distribution port. The interior surface of the light transfer tube is highly reflective so that the light transfers through the tube with minimal losses. An interchangeable luminaire is attached to the light distribution port and distributes light inside of a structure. A sun tracking device rotates the concentrator and the light transfer tube to optimize the receiving of solar light by the concentrator throughout the day. The system provides interior lighting, uses only renewable energy sources, and releases no carbon dioxide emissions into the atmosphere.

  7. Optimisation of a polygon mirror-based spectral filter for swept source optical coherence tomography (SS-OCT)

    NASA Astrophysics Data System (ADS)

    Everson, Michael; Duma, Virgil-Florin; Dobre, George

    2018-03-01

    Medical imaging using Optical Coherence Tomography (OCT) provides clinicians with 3D, high resolution reconstructions of microscopic structures, in depth. It has been initially developed for ophthalmology, in order to scan the retinas of patients to diagnose illness. The quality of the images depends upon their axial and lateral resolutions and the properties of the light being used. Research using a polygon mirror (PM) as a spectral filter in Swept Source OCT (SS-OCT) has resulted in a variety of different experimental arrangements. Although the application of PM-based SS-OCT sources has been successfully demonstrated, the combination of their components' fundamental properties and the overall impact they have on imaging performance is rarely reported. A more detailed examination of these properties would lead to a full description of their operation and to the best methods to employ if system performance is to be maximised. This work presents our current findings of on-going research into the optimisation of PM-based SS-OCT systems. A swept source spectral filter, consisting of a collimator, a transmission grating, a two-lens telescope and an off-axis PM with an end reflector mirror has been evaluated experimentally and compared with theoretical predictions. The system's performance has been compared for two different fibre collimators. Although the beam width on the grating is different for each of the two collimators, the spot size at the PM facet is made the same by selecting appropriate focal lengths. An improvement in the signal roll-off at the interferometer output of 1.0 dB/mm was obtained when using a 3.4 mm collimator compared to a 1.5 mm collimator.

  8. Normalization of a collimated 14.7 MeV neutron source in a neutron spectrometry system for benchmark experiments

    NASA Astrophysics Data System (ADS)

    Ofek, R.; Tsechanski, A.; Shani, G.

    1988-05-01

    In the present study a method used to normalize a collimated 14.7 MeV neutron beam is introduced. It combined a measurement of the fast neutron scalar flux passing through the collimator, using a copper foil activation, with a neutron transport calculation of the foil activation per unit source neutron, carried out by the discrete-ordinates transport code DOT 4.2. The geometry of the collimated neutron beam is composed of a D-T neutron source positioned 30 cm in front of a 6 cm diameter collimator, through a 120 cm thick paraffin wall. The neutron flux emitted from the D-T source was counted by an NE-213 scintillator, simultaneously with the irradiation of the copper foil. Thus, the determination of the normalization factor of the D-T source is used for an absolute flux calibration of the NE-213 scintillator. The major contributions to the uncertainty in the determination of the normalization factor, and their origins, are discussed.

  9. Characterization of the Los Alamos IPG YLR-6000 fiber laser using multiple optical paths and laser focusing optics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Milewski, John O; Bernal, John E

    2009-01-01

    Fiber laser technology has been identified as the replacement power source for the existing Los Alamos TA-55 production laser welding system. An IPG YLR-6000 fiber laser was purchased, installed at SM-66 R3, and accepted in February 2008. No characterization of the laser and no welding was performed in the Feb 2008 to May 2009 interval. T. Lienert and J. Bernal (Ref. 1, July 2009) determined the existing 200 mm Rofin collimator and focus heads used with the Rofin diode pumped lasers were inadequate for use with the IPG laser due to clipping of the IPG laser beam. Further efforts inmore » testing of the IPG laser with Optoskand fiber delivery optics and a Rofin 120 mm collimator proved problematic due to optical fiber damage. As a result, IPG design optical fibers were purchased as replacements for subsequent testing. Within the same interval, an IPG fiber-to-fiber (F2F) connector, custom built for LANL, (J. Milewski, S. Gravener, Ref.2) was demonstrated and accepted at IPG Oxford, MA in August 2009. An IPG service person was contracted to come to LANL to assist in the installation, training, troubleshooting and characterization of the multiple beam paths and help perform laser head optics characterization. The statement of work is provided below: In summary the laser system, optical fibers, F2F connector, Precitec head, and a modified Rofin type (w/120mm Optoskand collimator) IWindowIBoot system focus head (Figure 1) were shown to perform well at powers up to 6 kW CW. Power measurements, laser spot size measurements, and other characterization data and lessons learned are contained within this report. In addition, a number of issues were identified that will require future resolution.« less

  10. Freeform lens design for LED collimating illumination.

    PubMed

    Chen, Jin-Jia; Wang, Te-Yuan; Huang, Kuang-Lung; Liu, Te-Shu; Tsai, Ming-Da; Lin, Chin-Tang

    2012-05-07

    We present a simple freeform lens design method for an application to LED collimating illumination. The method is derived from a basic geometric-optics analysis and construction approach. By using this method, a highly collimating lens with LED chip size of 1.0 mm × 1.0 mm and optical simulation efficiency of 86.5% under a view angle of ± 5 deg is constructed. To verify the practical performance of the lens, a prototype of the collimator lens is also made, and an optical efficiency of 90.3% with a beam angle of 4.75 deg is measured.

  11. A comparison between using incoherent or coherent sources to align and test an adaptive optical telescope

    NASA Technical Reports Server (NTRS)

    Anderson, Richard

    1994-01-01

    The concept in the initial alignment of the segmented mirror adaptive optics telescope called the phased array mirror extendable large aperture telescope (Pamela) is to produce an optical transfer function (OTF) which closely approximates the diffraction limited value which would correspond to a system pupil function that is unity over the aperture and zero outside. There are differences in the theory of intensity measurements between coherent and incoherent radiation. As a result, some of the classical quantities which describe the performance of an optical system for incoherent radiation can not be defined for a coherent field. The most important quantity describing the quality of an optical system is the OTF and for a coherent source the OTF is not defined. Instead a coherent transfer function (CTF) is defined. The main conclusion of the paper is that an incoherent collimated source and not a collimated laser source is preferred to calibrate the Hartmann wavefront sensor (WFS) of an aligned adaptive optical system. A distant laser source can be used with minimum problems to correct the system for atmospheric turbulence. The collimation of the HeNe laser alignment source can be improved by using a very small pin hole in the spatial filter so only the central portion of the beam is transmitted and the beam from the filter is nearly constant in amplitude. The size of this pin hole will be limited by the sensitivity of the lateral effect diode (LEDD) elements.

  12. Hybrid Parallel-Slant Hole Collimators for SPECT Imaging

    NASA Astrophysics Data System (ADS)

    Bai, Chuanyong; Shao, Ling; Ye, Jinghan; Durbin, M.; Petrillo, M.

    2004-06-01

    We propose a new collimator geometry, the hybrid parallel-slant (HPS) hole geometry, to improve sensitivity for SPECT imaging with large field of view (LFOV) gamma cameras. A HPS collimator has one segment with parallel holes and one or more segments with slant holes. The collimator can be mounted on a conventional SPECT LFOV system that uses parallel-beam collimators, and no additional detector or collimator motion is required for data acquisition. The parallel segment of the collimator allows for the acquisition of a complete data set of the organs-of-interest and the slant segments provide additional data. In this work, simulation studies of an MCAT phantom were performed with a HPS collimator with one slant segment. The slant direction points from patient head to patient feet with a slant angle of 30/spl deg/. We simulated 64 projection views over 180/spl deg/ with the modeling of nonuniform attenuation effect, and then reconstructed images using an MLEM algorithm that incorporated the hybrid geometry. It was shown that sensitivity to the cardiac region of the phantom was increased by approximately 50% when using the HPS collimator compared with a parallel-hole collimator. No visible artifacts were observed in the myocardium and the signal-to-noise ratio (SNR) of the myocardium walls was improved. Compared with collimators with other geometries, using a HPS collimator has the following advantages: (a) significant sensitivity increase; (b) a complete data set obtained from the parallel segment that allows for artifact-free image reconstruction; and (c) no additional collimator or detector motion. This work demonstrates the potential value of hybrid geometry in collimator design for LFOV SPECT imaging.

  13. Muon spin rotation studies

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The bulk of the muon spin rotation research work centered around the development of the muon spin rotation facility at the Alternating Gradient Synchrotron (AGS) of Brookhaven National Laboratory (BNL). The collimation system was both designed and fabricated at Virginia State University. This improved collimation system, plus improvements in detectors and electronics enabled the acquisition of spectra free of background out to 15 microseconds. There were two runs at Brookhaven in 1984, one run was devoted primarily to beam development and the other run allowed several successful experiments to be performed. The effect of uniaxial strain on an Fe(Si) crystal at elevated temperature (360K) was measured and the results are incorporated herein. A complete analysis of Fe pulling data taken earlier is included.

  14. Minibeam radiotherapy with small animal irradiators; in vitro and in vivo feasibility studies

    NASA Astrophysics Data System (ADS)

    Bazyar, Soha; Inscoe, Christina R.; O'Brian, E. Timothy; Zhou, Otto; Lee, Yueh Z.

    2017-12-01

    Minibeam radiation therapy (MBRT) delivers an ultrahigh dose of x-ray (⩾100 Gy) in 200-1000 µm beams (peaks), separated by wider non-irradiated regions (valleys) usually as a single temporal fraction. Preclinical studies performed at synchrotron facilities revealed that MBRT is able to ablate tumors while maintaining normal tissue integrity. The main purpose of the present study was to develop an efficient and accessible method to perform MBRT using a conventional x-ray irradiator. We then tested this new method both in vitro and in vivo. Using commercially available lead ribbon and polyethylene sheets, we constructed a collimator that converted the cone beam of an industrial irradiator to 44 identical beams (collimator size  ≈  4  ×  10 cm). The dosimetry characteristics of the generated beams were evaluated using two different radiochromic films (beam FWHM  =  246  ±  32 µm center-to-center  =  926  ±  23 µm peak-to-valley dose ratio  =  24.35  ±  2.10 collimator relative output factor  =  0.84  ±  0.04). Clonogenic assays demonstrated the ability of our method to induce radiobiological cell death in two radioresistant murine tumor cell lines (TRP  =  glioblastoma B16-F10  =  melanoma). A radiobiological equivalent dose (RBE) was calculated by evaluating the acute skin response to graded doses of MBRT and conventional radiotherapy (CRT). Normal mouse skin demonstrated resistance to doses up to 150 Gy on peak. MBRT significantly extended the survival of mice with flank melanoma tumors compared to CRT when RBE were applied (overall p  <  0.001). Loss of spatial resolution deep in the tissue has been a major concern. The beams generated using our collimator maintained their resolution in vivo (mouse brain tissue) and up to 10 cm deep in the radiochromic film. In conclusion, the initial dosimetric, in vitro and in vivo evaluations confirmed the utility of this affordable and easy-to-replicate minibeam collimator for future preclinical studies.

  15. WE-DE-BRA-10: Development of a Novel Scanning Beam Low-Energy Intraoperative Radiation Therapy (SBIORT) System for Pancreatic Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wears, B; Mohiuddin, I; Flynn, R

    2016-06-15

    Purpose: Developing a compact collimator system and validating a 3D surface imaging module for a scanning beam low-energy x-ray radiation therapy (SBIORT) system that enables delivery of non-uniform radiation dose to targets with irregular shapes intraoperatively. Methods: SBIORT consists of a low energy x-ray source, a custom compact collimator module, a robotic arm, and a 3D surface imaging module. The 3D surface imaging system (structure sensor) is utilized for treatment planning and motion monitoring of the surgical cavity. SBIORT can deliver non-uniform dose distributions by dynamically moving the x-ray source assembly along optimal paths with various collimator apertures. The compactmore » collimator utilizes a dynamic shutter mechanism to form a variable square aperture. The accuracy and reproducibility of the collimator were evaluated using a high accuracy encoder and a high resolution camera platform. The dosimetrical characteristics of the collimator prototype were evaluated using EBT3 films with a Pantak Therapax unit. The accuracy and clinical feasibility of the 3D imaging system were evaluated using a phantom and a cadaver cavity. Results: The SBIORT collimator has a compact size: 66 mm diameter and 10 mm thickness with the maximum aperture of 20 mm. The mechanical experiment indicated the average accuracy of leaf position was 0.08 mm with a reproducibility of 0.25 mm at 95% confidence level. The dosimetry study indicated the collimator had a penumbra of 0.35 mm with a leaf transmission of 0.5%. 3D surface scans can be acquired in 5 seconds. The average difference between the acquired 3D surface and the ground truth is 1 mm with a standard deviation of 0.6 mm. Conclusion: This work demonstrates the feasibility of the compact collimator and 3D scanning system for the SBIORT. SBIORT is a way of delivering IORT with a compact system that requires minimum shielding of the procedure room. This research is supported by the University of Iowa Internal Funding Initiatives.« less

  16. Low-frequency ultrasonic Bessel-like collimated beam generation from radial modes of piezoelectric transducers

    DOE PAGES

    Chillara, Vamshi Krishna; Pantea, Cristian; Sinha, Dipen N.

    2017-02-06

    We present a very simple approach to generate a collimated ultrasonic beam that exploits the natural Bessel-like vibration pattern of the radial modes of a piezoelectric disc with lateral clamping. This eliminates the need for the conventional annular Bessel pattern of the electrodes with individual electrode excitation on the piezo-disc, thus simplifying the transducer design. Numerical and experimental studies are carried out to investigate the Bessel-like vibration patterns of these radial modes showing an excellent agreement between these two studies. Measured ultrasonic beam- pro les in water from the radial modes con rm the profile to be a Bessel beam.more » Collimated beam generation from radial modes is investigated using a coupled electromechanical finite-element model. It is found that clamping the lateral edges of piezoelectric transducers results in a high-degree of collimation with practically no side-lobes similar to a parametric array beam. Ultrasonic beam- profile measurements in water with both free and clamped piezoelectric transducer are presented. The collimated beam generation using the present technique of using the laterally clamped radial modes finds significant applications in low-frequency imaging through highly attenuating materials.« less

  17. Low-frequency ultrasonic Bessel-like collimated beam generation from radial modes of piezoelectric transducers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chillara, Vamshi Krishna; Pantea, Cristian; Sinha, Dipen N.

    We present a very simple approach to generate a collimated ultrasonic beam that exploits the natural Bessel-like vibration pattern of the radial modes of a piezoelectric disc with lateral clamping. This eliminates the need for the conventional annular Bessel pattern of the electrodes with individual electrode excitation on the piezo-disc, thus simplifying the transducer design. Numerical and experimental studies are carried out to investigate the Bessel-like vibration patterns of these radial modes showing an excellent agreement between these two studies. Measured ultrasonic beam- pro les in water from the radial modes con rm the profile to be a Bessel beam.more » Collimated beam generation from radial modes is investigated using a coupled electromechanical finite-element model. It is found that clamping the lateral edges of piezoelectric transducers results in a high-degree of collimation with practically no side-lobes similar to a parametric array beam. Ultrasonic beam- profile measurements in water with both free and clamped piezoelectric transducer are presented. The collimated beam generation using the present technique of using the laterally clamped radial modes finds significant applications in low-frequency imaging through highly attenuating materials.« less

  18. Monte Carlo design and simulation of a grid-type multi-layer pixel collimator for radiotherapy: Feasibility study

    NASA Astrophysics Data System (ADS)

    Yoon, Do-Kun; Jung, Joo-Young; Suh, Tae Suk

    2014-05-01

    In order to confirm the possibility of field application of a different type collimator with a multileaf collimator (MLC), we constructed a grid-type multi-layer pixel collimator (GTPC) by using a Monte Carlo n-particle simulation (MCNPX). In this research, a number of factors related to the performance of the GPTC were evaluated using simulated output data of a basic MLC model. A layer was comprised of a 1024-pixel collimator (5.0 × 5.0 mm2) which could operate individually as a grid-type collimator (32 × 32). A 30-layer collimator was constructed for a specific portal form to pass radiation through the opening and closing of each pixel cover. The radiation attenuation level and the leakage were compared between the GTPC modality simulation and MLC modeling (tungsten, 17.50 g/cm3, 5.0 × 70.0 × 160.0 mm3) currently used for a radiation field. Comparisons of the portal imaging, the lateral dose profile from a virtual water phantom, the dependence of the performance on the increase in the number of layers, the radiation intensity modulation verification, and the geometric error between the GTPC and the MLC were done using the MCNPX simulation data. From the simulation data, the intensity modulation of the GTPC showed a faster response than the MLC's (29.6%). In addition, the agreement between the doses that should be delivered to the target region was measured as 97.0%, and the GTPC system had an error below 0.01%, which is identical to that of MLC. A Monte Carlo simulation of the GTPC could be useful for verification of application possibilities. Because the line artifact is caused by the grid frame and the folded cover, a lineal dose transfer type is chosen for the operation of this system. However, the result of GTPC's performance showed that the methods of effective intensity modulation and the specific geometric beam shaping differed with the MLC modality.

  19. Adjustable mounting device for high-volume production of beam-shaping systems for high-power diode lasers

    NASA Astrophysics Data System (ADS)

    Haag, Sebastian; Bernhardt, Henning; Rübenach, Olaf; Haverkamp, Tobias; Müller, Tobias; Zontar, Daniel; Brecher, Christian

    2015-02-01

    In many applications for high-power diode lasers, the production of beam-shaping and homogenizing optical systems experience rising volumes and dynamical market demands. The automation of assembly processes on flexible and reconfigurable machines can contribute to a more responsive and scalable production. The paper presents a flexible mounting device designed for the challenging assembly of side-tab based optical systems. It provides design elements for precisely referencing and fixating two optical elements in a well-defined geometric relation. Side tabs are presented to the machine allowing the application of glue and a rotating mechanism allows the attachment to the optical elements. The device can be adjusted to fit different form factors and it can be used in high-volume assembly machines. The paper shows the utilization of the device for a collimation module consisting of a fast-axis and a slow-axis collimation lens. Results regarding the repeatability and process capability of bonding side tab assemblies as well as estimates from 3D simulation for overall performance indicators achieved such as cycle time and throughput will be discussed.

  20. A micro-scale plasma spectrometer for space and plasma edge applications (invited)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scime, E. E., E-mail: escime@wvu.edu; Keesee, A. M.; Elliott, D.

    2016-11-15

    A plasma spectrometer design based on advances in lithography and microchip stacking technologies is described. A series of curved plate energy analyzers, with an integrated collimator, is etched into a silicon wafer. Tests of spectrometer elements, the energy analyzer and collimator, were performed with a 5 keV electron beam. The measured collimator transmission and energy selectivity were in good agreement with design targets. A single wafer element could be used as a plasma processing or fusion first wall diagnostic.

  1. Radiation Safety Considerations Near Collimators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stevens, A. J.

    1997-04-15

    The primary collimators are clearly a concern as regards radiation safety since they are intended to be the place where "lost" beam particles interact. These collimators and the beam dumps, therefore, are expected to be the "hot spots" in the machine. Unfortunately, the amount of beam which will end up on the collimators is not really known. For the purposes of this note, the assumption will be made that, averaged over a year, 20% of the beam in each ring will interact in the limiting aperture collimator for that ring, and at most 10% of stored beam in in amore » single hour. Faults will also be considered, but the annual assumed beam loss will be shown to be the limiting factor. The annual beam per ring from the Beam Loss Scenario (BLS) is the equivalent of 5.5 x 10 14 au ions at 100 GeV/u. It should be noted that this number assumes operation at 4 times the design intensity for 38 weeks a year at 100% efficiency. The 20% loss assumption is somewhat higher than given by Ref. [1] because the internal dump aperture is larger than was assumed when the BLS was written and will therefore "catch" less lost particles than assumed at that time. For the purposes of the estimates made here, therefore, the loss assumption per primary collimator in normal operation are assumed to be 1.1 x 10 14 Au ions per year and 2.85 x 10 10 Au ions per hour. The last number is 10% of the maximum beam per ring per hour in the BLS which corresponds to 1.25 fill per hour. The assumption will also be made that both primary collimators are located downstream of the crossing point at 8 o'clock. In subsequent sections of this note the following potential problems are considered: (1) prompt radiation occupied regions nearest to the collimators, (2) skyshine, and (3) soil activation. Section VII recommends actions to address these problems.« less

  2. Protecting LHC components against radiation resulting from an unsynchronized beam abort

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nikolai V. Mokhov et al.

    2001-06-26

    The effect of possible accidental beam loss in the LHC on the IP5 and IP6 insertion elements is studied via realistic Monte Carlo simulations. The scenario studied is beam loss due to unsynchronized abort at an accidental prefire of one of the abort kicker modules. Simulations show that this beam loss would result in severe heating of the IP5 and IP6 superconducting (SC) quadrupoles. Contrary to the previous considerations with a stationary set of collimators in IP5, collimators in IP6 close to the cause are proposed: a movable collimator upstream of the Q4 quadrupole and a stationary one upstream ofmore » the extraction septumMSD. The calculated temperature rise in the optimal set of collimators is quite acceptable. All SC magnets are protected by these collimators against damage.« less

  3. Deep turbulence effects mitigation with coherent combining of 21 laser beams over 7 km.

    PubMed

    Weyrauch, Thomas; Vorontsov, Mikhail; Mangano, Joseph; Ovchinnikov, Vladimir; Bricker, David; Polnau, Ernst; Rostov, Andrey

    2016-02-15

    We demonstrate coherent beam combining and adaptive mitigation of atmospheric turbulence effects over 7 km under strong scintillation conditions using a coherent fiber array laser transmitter operating in a target-in-the-loop setting. The transmitter system is composed of a densely packed array of 21 fiber collimators with integrated capabilities for piston, tip, and tilt control of the outgoing beams wavefront phases. A small cat's-eye retro reflector was used for evaluation of beam combining and turbulence compensation performance at the target plane, and to provide the feedback signal for control of piston and tip/tilt phases of the transmitted beams using the stochastic parallel gradient descent maximization of the power-in-the-bucket metric.

  4. Characteristics and performance of the first commercial multileaf collimator for a robotic radiosurgery system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fürweger, Christoph, E-mail: christoph.fuerweger@cyber-knife.net; Prins, Paulette; Coskan, Harun

    Purpose: The “InCise™ multileaf-collimator (MLC)” is the first commercial MLC to be mounted on a robotic SRS/SBRT platform (CyberKnife). The authors assessed characteristics and performance of this novel device in a preclinical five months test period. Methods: Commissioning beam data were acquired with unshielded diodes. EBT3 radiochromic films were employed for measurement of transmission, leaf/bank position accuracy (garden fence) before and after exercising the MLC, for end-to-end testing and further characterization of the beam. The robot workspace with MLC was assessed analytically by transformation to an Euler geometry (“plane,” “gantry,” and “collimator” angles) and by measuring pointing accuracy at eachmore » node. Stability over time was evaluated in picket fence and adapted Winston–Lutz tests (AQA). Results: Beam penumbrae (80%–20%, with 100% = 2 × dose at inflection point for field sizes ≥ 50 × 50 mm{sup 2}) were 2.2–3.7 mm for square fields in reference condition (source-axis-distance 800 mm, depth 15 mm) and depended on field size and off-axis position. Transmission and leakage did not exceed 0.5%. Accessible clinical workspace with MLC covered non-coplanar gantry angles of [−113°; +112°] and collimator angles of [−100°; +107°], with an average robot pointing accuracy of 0.12 ± 0.09 mm. For vertical beams, garden fence tests exhibited an average leaf positioning error of ≤0.2 mm, which increased by 0.25 and 0.30 mm (banks X1 and X2) with leaves traveling parallel to gravity. After execution of a leaf motion stress routine, garden fence tests showed slightly increased jaggedness and allowed to identify one malfunctioning leaf motor. Total system accuracy with MLC was 0.38 ± 0.05 mm in nine end-to-end tests. Picket fence and AQA tests displayed stable results over the test period. Conclusions: The InCise™ MLC for CyberKnife showed high accuracy and adequate characteristics for SRS/SBRT applications. MLC performance after exercise demands specific quality assurance measures.« less

  5. Electron intensity modulation for mixed-beam radiation therapy with an x-ray multi-leaf collimator

    NASA Astrophysics Data System (ADS)

    Weinberg, Rebecca

    The current standard treatment for head and neck cancer at our institution uses intensity-modulated x-ray therapy (IMRT), which improves target coverage and sparing of critical structures by delivering complex fluence patterns from a variety of beam directions to conform dose distributions to the shape of the target volume. The standard treatment for breast patients is field-in-field forward-planned IMRT, with initial tangential fields and additional reduced-weight tangents with blocking to minimize hot spots. For these treatment sites, the addition of electrons has the potential of improving target coverage and sparing of critical structures due to rapid dose falloff with depth and reduced exit dose. In this work, the use of mixed-beam therapy (MBT), i.e., combined intensity-modulated electron and x-ray beams using the x-ray multi-leaf collimator (MLC), was explored. The hypothesis of this study was that addition of intensity-modulated electron beams to existing clinical IMRT plans would produce MBT plans that were superior to the original IMRT plans for at least 50% of selected head and neck and 50% of breast cases. Dose calculations for electron beams collimated by the MLC were performed with Monte Carlo methods. An automation system was created to facilitate communication between the dose calculation engine and the treatment planning system. Energy and intensity modulation of the electron beams was accomplished by dividing the electron beams into 2x2-cm2 beamlets, which were then beam-weight optimized along with intensity-modulated x-ray beams. Treatment plans were optimized to obtain equivalent target dose coverage, and then compared with the original treatment plans. MBT treatment plans were evaluated by participating physicians with respect to target coverage, normal structure dose, and overall plan quality in comparison with original clinical plans. The physician evaluations did not support the hypothesis for either site, with MBT selected as superior in 1 out of the 15 head and neck cases (p=1) and 6 out of 18 breast cases (p=0.95). While MBT was not shown to be superior to IMRT, reductions were observed in doses to critical structures distal to the target along the electron beam direction and to non-target tissues, at the expense of target coverage and dose homogeneity.

  6. SU-F-T-131: No Increase in Biological Effectiveness Through Collimator Scattered Low Energy Protons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matsuura, T; Takao, S; Matsuzaki, Y

    Purpose: To reduce the lateral penumbra of low-energy proton beams, brass collimators are often used in spot-scanning proton therapy (SSPT). This study investigates the increase in biological effectiveness through collimator scattered protons in SSPT. Methods: The SSPT system of the Hokkaido University Hospital Proton Beam Therapy Center, which consists of a scanning nozzle, a 2-cm thick brass collimator, and a 4-cm thick energy absorber, was simulated with our validated Geant4 Monte Carlo code (ver. 9.3). A water phantom was irradiated with proton pencil beams of 76, 110, and 143 MeV. The tested collimator opening areas (COA) were 5×5, 10×10, andmore » 15×15 cm{sup 2}. Comparisons were made among the dose-averaged LET values of protons that hit the collimators (LETDColl), protons that did not hit the collimators (LETDNoColl), and all protons (LETDTotal). X-ray equivalent doses (Deq) were calculated using the linear-quadratic model with LETDNoColl and LETDTotal, and their maximum difference was determined over regions where the physical dose was greater than 10% of the peak dose of 2 Gy. Results: The ratio of the dose contribution of collimator scattered protons to that of all protons, defined as λ, was large at high proton energies and large COAs. The maximum λ value ranged from 3% (76 MeV, 5×5 cm{sup 2}) to 29% (143 MeV, 15×15 cm{sup 2}). Moreover, a large difference between LETDColl and LETDNoColl was only found in regions where λ was below 20% (ΔLETD > 2 keV/µm) and 8% (ΔLETD > 5 keV/µm). Consequently, the maximum difference between LETDNoColl and LETDTotal was as small as 0.8 keV/µm in all simulated voxels, and the difference of Deq reached a maximum of 1.5% that of the peak dose obtained at the water surface with a 76 MeV beam. Conclusion: Although collimator scattered protons have high LET, they only increase the physical dose, not the biological effectiveness.« less

  7. VUV-soft x-ray beamline for spectroscopy and calibration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bartlett, R.J.; Trela, W.J.; Southworth, S.H.

    1986-01-01

    We describe the design and performance of the Los Alamos VUV synchrotron radiation beamline, U3C, on the VUV ring of the National Synchrotron Light Source at Brookhaven National Laboratory. The beamline uses separate function optics to collect and focus the horizontally and vertically diverging beam. The monochromator is a grazing incidence Roland circle instrument of the extended grasshopper design (ERG). A post monochromator refocusing mirror is used to focus or collimate the diverging beam from the monochromator. The beamline control and diagnostics systems are also discussed.

  8. Radiation leakage dose from Elekta electron collimation system

    PubMed Central

    Hogstrom, Kenneth R.; Carver, Robert L.

    2016-01-01

    This study provided baseline data required for a greater project, whose objective was to design a new Elekta electron collimation system having significantly lighter electron applicators with equally low out‐of field leakage dose. Specifically, off‐axis dose profiles for the electron collimation system of our uniquely configured Elekta Infinity accelerator with the MLCi2 treatment head were measured and calculated for two primary purposes: 1) to evaluate and document the out‐of‐field leakage dose in the patient plane and 2) to validate the dose distributions calculated using a BEAMnrc Monte Carlo (MC) model for out‐of‐field dose profiles. Off‐axis dose profiles were measured in a water phantom at 100 cm SSD for 1 and 2 cm depths along the in‐plane, cross‐plane, and both diagonal axes using a cylindrical ionization chamber with the 10×10 and 20×20 cm2 applicators and 7, 13, and 20 MeV beams. Dose distributions were calculated using a previously developed BEAMnrc MC model of the Elekta Infinity accelerator for the same beam energies and applicator sizes and compared with measurements. Measured results showed that the in‐field beam flatness met our acceptance criteria (±3% on major and ±4% on diagonal axes) and that out‐of‐field mean and maximum percent leakage doses in the patient plane met acceptance criteria as specified by the International Electrotechnical Commission (IEC). Cross‐plane out‐of‐field dose profiles showed greater leakage dose than in‐plane profiles, attributed to the curved edges of the upper X‐ray jaws and multileaf collimator. Mean leakage doses increased with beam energy, being 0.93% and 0.85% of maximum central axis dose for the 10×10 and 20×20 cm2 applicators, respectively, at 20 MeV. MC calculations predicted the measured dose to within 0.1% in most profiles outside the radiation field; however, excluding modeling of nontrimmer applicator components led to calculations exceeding measured data by as much as 0.2% for some regions along the in‐plane axis. Using EGSnrc LATCH bit filtering to separately calculate out‐of‐field leakage dose components (photon dose, primary electron dose, and electron dose arising from interactions in various collimating components), MC calculations revealed that the primary electron dose in the out‐of‐field leakage region was small and decreased as beam energy increased. Also, both the photon dose component and electron dose component resulting from collimator scatter dominated the leakage dose, increasing with increasing beam energy. We concluded that our custom Elekta Infinity with the MLCi2 treatment head met IEC leakage dose criteria in the patient plane. Also, accuracy of our MC model should be sufficient for our use in the design of a new, improved electron collimation system. PACS number(s): 87.56.nk, 87.10.Rt, 87.56.J PMID:27685101

  9. Variable-energy collimator for high-energy radiation

    DOEpatents

    Hill, R.A.

    1982-03-03

    An apparatus is disclosed providing a variable aperture energy beam collimator. A plurality of beam opaque blocks are in sliding interface edge contact to form a variable aperture. The blocks may be offset at the apex angle to provide a non-equilateral aperture. A plurality of collimator block assemblies may be employed for providing a channel defining a collimated beam. Adjacent assemblies are inverted front-to-back with respect to one another for preventing noncollimated ;energy from emergine from the apparatus. An adjustment mechanism comprises a cable attached to at least one block and a hand wheel mechanism for operating the cable. The blocks are supported by guide rods engaging slide brackets on the blocks. The guide rods are pivotally connected at each end to intermediate actuators supported on rotatable shafts to change the shape of the aperture. A divergent collimated beam may be obtained by adjusting the apertures of adjacent stages to be unequal.

  10. Variable aperture collimator for high energy radiation

    DOEpatents

    Hill, Ronald A.

    1984-05-22

    An apparatus is disclosed providing a variable aperture energy beam collimator. A plurality of beam opaque blocks are in sliding interface edge contact to form a variable aperture. The blocks may be offset at the apex angle to provide a non-equilateral aperture. A plurality of collimator block assemblies may be employed for providing a channel defining a collimated beam. Adjacent assemblies are inverted front-to-back with respect to one another for preventing noncollimated energy from emerging from the apparatus. An adjustment mechanism comprises a cable attached to at least one block and a hand wheel mechanism for operating the cable. The blocks are supported by guide rods engaging slide brackets on the blocks. The guide rods are pivotally connected at each end to intermediate actuators supported on rotatable shafts to change the shape of the aperture. A divergent collimated beam may be obtained by adjusting the apertures of adjacent stages to be unequal.

  11. Dosimetric characterization of a bi-directional micromultileaf collimator for stereotactic applications.

    PubMed

    Bucciolini, M; Russo, S; Banci Buonamici, F; Pini, S; Silli, P

    2002-07-01

    A 6 MV photon beam from Linac SL75-5 has been collimated with a new micromultileaf device that is able to shape the field in the two orthogonal directions with four banks of leaves. This is the first clinical installation of the collimator and in this paper the dosimetric characterization of the system is reported. The dosimetric parameters required by the treatment planning system used for the dose calculation in the patient are: tissue maximum ratios, output factors, transmission and leakage of the leaves, penumbra values. Ionization chambers, silicon diode, radiographic films, and LiF thermoluminescent dosimeters have been employed for measurements of absolute dose and beam dosimetric data. Measurements with different dosimeters supply results in reasonable agreement among them and consistent with data available in literature for other models of micromultileaf collimator; that permits the use of the measured parameters for clinical applications. The discrepancies between results obtained with the different detectors (around 2%) for the analyzed parameters can be considered an indication of the accuracy that can be reached by current stereotactic dosimetry.

  12. Device to color modulate a stationary light beam gives high intensity

    NASA Technical Reports Server (NTRS)

    Gantz, W. A.

    1966-01-01

    Signal controlled system color modulates a beam of light while also providing high intensity and a stationary beam, either collimated or focused. The color modulation acquired by the presented system can be compatible with any color film by employing color filters formed to provide a color wedge having a color distribution compatible with the films color sensitivity.

  13. Ion beam neutralization using three-dimensional electron confinement by surface modification of magnetic poles

    NASA Astrophysics Data System (ADS)

    Nicolaescu, Dan; Sakai, Shigeki; Gotoh, Yasuhito; Ishikawa, Junzo

    2011-07-01

    Advanced implantation systems used for semiconductor processing require transportation of quasi-parallel ion beams, which have low energy (11B+, 31P+,75As+, Eion=200-1000 eV). Divergence of the ion beam due to space charge effects can be compensated through injection of electrons into different regions of the ion beam. The present study shows that electron confinement takes place in regions of strong magnetic field such as collimator magnet provided with surface mirror magnetic fields and that divergence of the ion beam passing through such regions is largely reduced. Modeling results have been obtained using Opera3D/Tosca/Scala. Electrons may be provided by collision between ions and residual gas molecules or may be injected by field emitter arrays. The size of surface magnets is chosen such as not to disturb ion beam collimation, making the approach compatible with ion beam systems. Surface magnets may form thin magnetic layers with thickness h=0.5 mm or less. Conditions for spacing of surface magnet arrays for optimal electron confinement are outlined.

  14. Development of Prior Image-Based, High-Quality, Low-Dose Kilovoltage Cone Beam CT for Use in Adaptive Radiotherapy of Prostate Cancer

    DTIC Science & Technology

    2011-05-01

    for the research in the next year. The aims in the next year include further develop- ment of the prior image- based , narrowly collimated CBCT imaging...further investigation planned for the next year. 5 BODY 1 Research Accomplishments 1.1 Implement narrow beam collimation for CBCT ROI imaging I have...noise level to mimic different mAs used in clinical and research modes of the CBCT system. Based upon experiences with the numerical phantom, I designed

  15. Impact of large x-ray beam collimation on image quality

    NASA Astrophysics Data System (ADS)

    Racine, Damien; Ba, Alexandre; Ott, Julien G.; Bochud, François O.; Verdun, Francis R.

    2016-03-01

    Large X-ray beam collimation in computed tomography (CT) opens the way to new image acquisition techniques and improves patient management for several clinical indications. The systems that offer large X-ray beam collimation enable, in particular, a whole region of interest to be investigated with an excellent temporal resolution. However, one of the potential drawbacks of this option might be a noticeable difference in image quality along the z-axis when compared with the standard helical acquisition mode using more restricted X-ray beam collimations. The aim of this project is to investigate the impact of the use of large X-ray beam collimation and new iterative reconstruction on noise properties, spatial resolution and low contrast detectability (LCD). An anthropomorphic phantom and a custom made phantom were scanned on a GE Revolution CT. The images were reconstructed respectively with ASIR-V at 0% and 50%. Noise power spectra, to evaluate the noise properties, and Target Transfer Functions, to evaluate the spatial resolution, were computed. Then, a Channelized Hotelling Observer with Gabor and Dense Difference of Gaussian channels was used to evaluate the LCD using the Percentage correct as a figure of merit. Noticeable differences of 3D noise power spectra and MTF have been recorded; however no significant difference appeared when dealing with the LCD criteria. As expected the use of iterative reconstruction, for a given CTDIvol level, allowed a significant gain in LCD in comparison to ASIR-V 0%. In addition, the outcomes of the NPS and TTF metrics led to results that would contradict the outcomes of CHO model observers if used for a NPWE model observer (Non- Prewhitening With Eye filter). The unit investigated provides major advantages for cardiac diagnosis without impairing the image quality level of standard chest or abdominal acquisitions.

  16. Secondary Neutron Doses to Pediatric Patients During Intracranial Proton Therapy: Monte Carlo Simulation of the Neutron Energy Spectrum and its Organ Doses.

    PubMed

    Matsumoto, Shinnosuke; Koba, Yusuke; Kohno, Ryosuke; Lee, Choonsik; Bolch, Wesley E; Kai, Michiaki

    2016-04-01

    Proton therapy has the physical advantage of a Bragg peak that can provide a better dose distribution than conventional x-ray therapy. However, radiation exposure of normal tissues cannot be ignored because it is likely to increase the risk of secondary cancer. Evaluating secondary neutrons generated by the interaction of the proton beam with the treatment beam-line structure is necessary; thus, performing the optimization of radiation protection in proton therapy is required. In this research, the organ dose and energy spectrum were calculated from secondary neutrons using Monte Carlo simulations. The Monte Carlo code known as the Particle and Heavy Ion Transport code System (PHITS) was used to simulate the transport proton and its interaction with the treatment beam-line structure that modeled the double scattering body of the treatment nozzle at the National Cancer Center Hospital East. The doses of the organs in a hybrid computational phantom simulating a 5-y-old boy were calculated. In general, secondary neutron doses were found to decrease with increasing distance to the treatment field. Secondary neutron energy spectra were characterized by incident neutrons with three energy peaks: 1×10, 1, and 100 MeV. A block collimator and a patient collimator contributed significantly to organ doses. In particular, the secondary neutrons from the patient collimator were 30 times higher than those from the first scatter. These results suggested that proactive protection will be required in the design of the treatment beam-line structures and that organ doses from secondary neutrons may be able to be reduced.

  17. Monitor unit settings for intensity modulated beams delivered using a step-and-shoot approach.

    PubMed

    Sharpe, M B; Miller, B M; Yan, D; Wong, J W

    2000-12-01

    Two linear accelerators have been commissioned for delivering IMRT treatments using a step-and-shoot approach. To assess beam startup stability for 6 and 18 MV x-ray beams, dose delivered per monitor unit (MU), beam flatness, and beam symmetry were measured as a function of the total number of MU delivered at a clinical dose rate of 400 MU per minute. Relative to a 100 MU exposure, the dose delivered per MU by both linear accelerators was found to be within +/-2% for exposures larger than 4 MU. Beam flatness and symmetry also met accepted quality assurance standards for a minimum exposure of 4 MU. We have found that the performance of the two machines under study is well suited to the delivery of step-and-shoot IMRT. A system of dose calculation has also been commissioned for applying head scatter corrections to fields as small as 1x1 cm2. The accuracy and precision of the relative output calculations in water was validated for small fields and fields offset from the axis of collimator rotation. For both 6 and 18 MV x-ray beams, the dose per MU calculated in a water phantom agrees with measured data to within 1% on average, with a maximum deviation of 2.5%. The largest output factor discrepancies were seen when the actual radiation field size deviated from the set field size. The measured output in water can vary by as much 16% for 1x1 cm2 fields, when the measured field size deviates from the set field size by 2 mm. For a 1 mm deviation, this discrepancy was reduced to 8%. Steps should be taken to ensure collimator precision is tightly controlled when using such small fields. If this is not possible, very small fields should not contribute to a significant portion of the treatment, or uncertainties in the collimator position may effect the accuracy of the dose delivered.

  18. Design of a modulated orthovoltage stereotactic radiosurgery system.

    PubMed

    Fagerstrom, Jessica M; Bender, Edward T; Lawless, Michael J; Culberson, Wesley S

    2017-07-01

    To achieve stereotactic radiosurgery (SRS) dose distributions with sharp gradients using orthovoltage energy fluence modulation with inverse planning optimization techniques. A pencil beam model was used to calculate dose distributions from an orthovoltage unit at 250 kVp. Kernels for the model were derived using Monte Carlo methods. A Genetic Algorithm search heuristic was used to optimize the spatial distribution of added tungsten filtration to achieve dose distributions with sharp dose gradients. Optimizations were performed for depths of 2.5, 5.0, and 7.5 cm, with cone sizes of 5, 6, 8, and 10 mm. In addition to the beam profiles, 4π isocentric irradiation geometries were modeled to examine dose at 0.07 mm depth, a representative skin depth, for the low energy beams. Profiles from 4π irradiations of a constant target volume, assuming maximally conformal coverage, were compared. Finally, dose deposition in bone compared to tissue in this energy range was examined. Based on the results of the optimization, circularly symmetric tungsten filters were designed to modulate the orthovoltage beam across the apertures of SRS cone collimators. For each depth and cone size combination examined, the beam flatness and 80-20% and 90-10% penumbrae were calculated for both standard, open cone-collimated beams as well as for optimized, filtered beams. For all configurations tested, the modulated beam profiles had decreased penumbra widths and flatness statistics at depth. Profiles for the optimized, filtered orthovoltage beams also offered decreases in these metrics compared to measured linear accelerator cone-based SRS profiles. The dose at 0.07 mm depth in the 4π isocentric irradiation geometries was higher for the modulated beams compared to unmodulated beams; however, the modulated dose at 0.07 mm depth remained <0.025% of the central, maximum dose. The 4π profiles irradiating a constant target volume showed improved statistics for the modulated, filtered distribution compared to the standard, open cone-collimated distribution. Simulations of tissue and bone confirmed previously published results that a higher energy beam (≥ 200 keV) would be preferable, but the 250 kVp beam was chosen for this work because it is available for future measurements. A methodology has been described that may be used to optimize the spatial distribution of added filtration material in an orthovoltage SRS beam to result in dose distributions with decreased flatness and penumbra statistics compared to standard open cones. This work provides the mathematical foundation for a novel, orthovoltage energy fluence-modulated SRS system. © 2017 American Association of Physicists in Medicine.

  19. Evaluation of performance of the MACAO systems at the VLTI

    NASA Astrophysics Data System (ADS)

    Rengaswamy, Sridharan; Haguenauer, Pierre; Brillant, Stephane; Cortes, Angela; Girard, Julien H.; Guisard, Stephane; Paufique, Jérôme; Pino, Andres

    2010-07-01

    Multiple Application Curvature Adaptive Optics (MACAO) systems are used at the coudé focus of the unit telescopes (UTs) at the La-Silla Paranal Observatory, Paranal, to correct for the wave-front aberrations induced by the atmosphere. These systems are in operation since 2005 and are designed to provide beams with 10 mas residual rms tip-tilt error to the VLTI laboratory. We have initiated several technical studies such as measuring the Strehl ratio of the images recorded at the guiding camera of the VLTI, establishing the optimum setup of the MACAO to get collimated and focused beam down to the VLTI laboratory and to the instruments, and ascertaining the data generated by the real time computer, all aimed at characterizing and improving the overall performance of these systems. In this paper we report the current status of these studies.

  20. Application of Traditional and Nanostructure Materials for Medical Electron Beams Collimation: Numerical Simulation

    NASA Astrophysics Data System (ADS)

    Miloichikova, I. A.; Stuchebrov, S. G.; Zhaksybayeva, G. K.; Wagner, A. R.

    2015-11-01

    Nowadays, the commercial application of the electron accelerators grows in the industry, in the research investigations, in the medical diagnosis and treatment. In this regard, the electron beam profile modification in accordance with specific purposes is an actual task. In this paper the model of the TPU microtron extracted electron beam developed in the program “Computer Laboratory (PCLab)” is described. The internal beam divergence influence for the electron beam profile and depth dose distribution in the air is considered. The possibility of using the nanostructure materials for the electron beam formation was analyzed. The simulation data of the electron beam shape collimated by different materials (lead, corund- zirconia nanoceramic, gypsum) are shown. The collimator material influence for the electron beam profile and shape are analyzed.

  1. Multileaf collimator-based linear accelerator radiosurgery: five-year efficiency analysis.

    PubMed

    Lawson, Joshua D; Fox, Tim; Waller, Anthony F; Davis, Lawrence; Crocker, Ian

    2009-03-01

    In 1989, Emory University initiated a linear accelerator (linac) radiosurgery program using circular collimators. In 2001, the program converted to a multileaf collimator. Since then, the treatment parameters of each patient have been stored in the record-and-verify system. Three major changes have occurred in the radiosurgery program in the past 6 years: in 2002, treatment was changed from static conformal beams to dynamic conformal arc (DCA) therapy, and all patients were imaged before treatment. Beginning in 2005, a linac was used, with the opportunity to treat at higher dose rates (600-1,000 monitor units/min). The aim of this study was to analyze the time required to deliver radiosurgery and the factors affecting treatment delivery. Benchmark data are provided for centers contemplating initiating linac radiosurgery programs. Custom software was developed to mine the record-and-verify system database and automatically perform a chart review on patients who underwent stereotactic radiosurgery from March 2001 to October 2006. The software extracted 510 patients who underwent stereotactic radiosurgery, and the following information was recorded for each patient: treatment technique, treatment time (from initiation of imaging, if done, to completion of therapy), number of isocenters, number of fields, total monitor units, and dose rate. Of the 510 patients, 395 were treated with DCA therapy and 115 with static conformal beams. The average number of isocenters treated was 1.06 (range, 1-4). The average times to deliver treatment were 24.1 minutes for patients who underwent DCA therapy and 19.3 minutes for those treated with static conformal beams, reflecting the lack of imaging in the latter patients. Eighty percent of patients were treated in <30 minutes. For the patients who underwent DCA therapy, the times required to treat 1, 2, 3, and 4 isocenters were 23.9, 24.8, 33.1, and 37.8 minutes, respectively. Average beam-on time for these patients was 11.4 minutes. There has been no significant reduction in treatment delivery with the use of 1,000 monitor units/min, reflecting the fact that beam-on time is not the major determinant of overall treatment time. Multileaf collimator-based linac radiosurgery can be delivered efficiently in <30 minutes in the vast majority of patients. Given the limited treatment room utilization required for stereotactic radiosurgery treatments, this study calls into question the need for a dedicated radiosurgery unit for even busy treatment centers.

  2. 1-D ELECTRO-OPTIC BEAM STEERING DEVICE

    PubMed Central

    Wang, Wei-Chih; Tsui, Chi Leung

    2011-01-01

    In this paper, we present the design and fabrication of a 1D beam steering device based on planar electro-optic thermal-plastic prisms and a collimator lens array. With the elimination of moving parts, the proposed device is able to overcome the mechanical limitations of present scanning devices, such as fatigue and low operating frequency, while maintaining a small system footprint (~0.5mm×0.5mm). From experimental data, our prototype device is able to achieve a maximum deflection angle of 5.6° for a single stage prism design and 29.2° for a cascaded three prisms stage design. The lens array shows a 4µm collimated beam diameter. PMID:22199458

  3. Improved ion containment using a ring-cusp ion thruster

    NASA Technical Reports Server (NTRS)

    Sovey, J. S.

    1982-01-01

    A 30-centimeter diameter ring-cusp ion thruster is described which operates at inert gas ion beam currents up to about 7 ampere, with significant improvements in discharge chamber performance over conventional divergent-field thrusters. The thruster has strong boundary ring-cusp magnetic fields, a diverging field on the cathode region, and a nearly field-free volume upstream of the ion extraction system. Minimum ion beam production costs of 90 to 100 watts per beam ampere (W/A) were obtained for argon, krypton and xenon. Propellant efficiencies in excess of 0.90 were achieved at 100 to 120 W/A for the three inert gases. The ion beam charge-state was documented with a collimating mass spectrometer probe to allow evaluation of overall thruster efficiencies.

  4. Time delay spectrum conditioner

    DOEpatents

    Greiner, Norman R.

    1980-01-01

    A device for delaying specified frequencies of a multiple frequency laser beam. The device separates the multiple frequency beam into a series of spatially separated single frequency beams. The propagation distance of the single frequency beam is subsequently altered to provide the desired delay for each specific frequency. Focusing reflectors can be utilized to provide a simple but nonadjustable system or, flat reflectors with collimating and focusing optics can be utilized to provide an adjustable system.

  5. Significance of including field non-uniformities such as the heel effect and beam scatter in the determination of the skin dose distribution during interventional fluoroscopic procedures

    NASA Astrophysics Data System (ADS)

    Rana, Vijay; Gill, Kamaljit; Rudin, Stephen; Bednarek, Daniel R.

    2012-03-01

    The current version of the real-time skin-dose-tracking system (DTS) we have developed assumes the exposure is contained within the collimated beam and is uniform except for inverse-square variation. This study investigates the significance of factors that contribute to beam non-uniformity such as the heel effect and backscatter from the patient to areas of the skin inside and outside the collimated beam. Dose-calibrated Gafchromic film (XR-RV3, ISP) was placed in the beam in the plane of the patient table at a position 15 cm tube-side of isocenter on a Toshiba Infinix C-Arm system. Separate exposures were made with the film in contact with a block of 20-cm solid water providing backscatter and with the film suspended in air without backscatter, both with and without the table in the beam. The film was scanned to obtain dose profiles and comparison of the profiles for the various conditions allowed a determination of field non-uniformity and backscatter contribution. With the solid-water phantom and with the collimator opened completely for the 20-cm mode, the dose profile decreased by about 40% on the anode side of the field. Backscatter falloff at the beam edge was about 10% from the center and extra-beam backscatter decreased slowly with distance from the field, being about 3% of the beam maximum at 6 cm from the edge. Determination of the magnitude of these factors will allow them to be included in the skin-dose-distribution calculation and should provide a more accurate determination of peak-skin dose for the DTS.

  6. SU-G-TeP2-04: Comprehensive Machine Isocenter Evaluation with Separation of Gantry, Collimator, and Table Variables

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hancock, S; Clements, C; Hyer, D

    2016-06-15

    Purpose: To develop and demonstrate application of a method that characterizes deviation of linac x-ray beams from the centroid of the volumetric radiation isocenter as a function of gantry, collimator, and table variables. Methods: A set of Winston-Lutz ball-bearing images was used to determine the gantry radiation isocenter as the midrange of deviation values resulting from gantry and collimator rotation. Also determined were displacement of table axis from gantry isocenter and recommended table axis adjustment. The method, previously reported, has been extended to include the effect of collimator walkout by obtaining measurements with 0 and 180 degree collimator rotation formore » each gantry angle. Twelve images were used to characterize the volumetric isocenter for the full range of available gantry, collimator, and table rotations. Results: Three Varian True Beam, two Elekta Infinity and four Versa HD linacs at five institutions were tested using identical methodology. Varian linacs exhibited substantially less deviation due to head sag than Elekta linacs (0.4 mm vs. 1.2 mm on average). One linac from each manufacturer had additional isocenter deviation of 0.3 to 0.4 mm due to jaw instability with gantry and collimator rotation. For all linacs, the achievable isocenter tolerance was dependent on adjustment of collimator position offset, transverse position steering, and alignment of the table axis with gantry isocenter, facilitated by these test results. The pattern and magnitude of table axis wobble vs. table angle was reproducible and unique to each machine. Conclusion: This new method provides a comprehensive set of isocenter deviation values including all variables. It effectively facilitates minimization of deviation between beam center and target (ball-bearing) position. This method was used to quantify the effect of jaw instability on isocenter deviation and to identify the offending jaw. The test is suitable for incorporation into a routine machine QA program. Software development was performed by Radiological Imaging Technology, Inc.« less

  7. The "collimator monitoring fill factor" of a two-dimensional detector array, a measure of its ability to detect collimation errors.

    PubMed

    Stelljes, Tenzin Sonam; Looe, Hui Khee; Harder, Dietrich; Poppe, Björn

    2017-03-01

    Two-dimensional detector arrays are routinely used for constancy checks and treatment plan verification in photon-beam radiotherapy. In addition to the spatial resolution of the dose profiles, the "coverage" of the radiation field with respect to the detection of any beam collimation deficiency appears as the second characteristic feature of a detector array. The here proposed "collimator monitoring fill factor" (CM fill factor) has been conceived to serve as a quantitative characteristic of this "coverage". The CM fill factor is defined as the probability of a 2D array to detect any collimator position error. Therefore, it is represented by the ratio of the "sensitive area" of a single detector, in which collimator position errors are detectable, and the geometrical "cell area" associated with this detector within the array. Numerical values of the CM fill factor have been Monte Carlo simulated for 2D detector arrays equipped with air-vented ionization chambers, liquid-filled ionization chambers and diode detectors and were compared with the "FWHM fill factor" defined by Gago-Arias et al. (2012). For arrays with vented ionization chambers, the differences between the CM fill factor and the FWHM fill factor are moderate, but occasionally the latter exceeds unity. For narrower detectors such as liquid-filled ionization chambers and Si diodes and for small sampling distances, large differences between the FWHM fill factor and the CM fill factor have been observed. These differences can be explained by the shapes of the fluence response functions of these narrow detectors. A new parameter "collimator monitoring fill factor" (CM fill factor), applicable to quantitate the collimator position error detection probability of a 2D detector array, has been proposed. It is designed as a help in classifying the clinical performance of two-dimensional detector arrays in photon-beam radiotherapy. © 2017 American Association of Physicists in Medicine.

  8. The radiated electromagnetic field from collimated gamma rays and electron beams in air

    NASA Astrophysics Data System (ADS)

    Tumolillo, T. A.; Wondra, J. P.; Hobbs, W. E.; Smith, K.

    1980-12-01

    Nuclear weapons effects computer codes are used to study the electromagnetic field produced by gamma rays or by highly relativistic electron beams moving through the air. Consideration is given to large-area electron and gamma beams, small-area electron beams, variation of total beam current, variation of pressure in the beam channel, variation of the beam rise time, variation of beam radius, far-field radiated signals, and induced current on a system from a charged-particle beam. The work has application to system EMP coupling from nuclear weapons or charged-particle-beam weapons.

  9. Propagation of a cosh-Gaussian beam through an optical system in turbulent atmosphere.

    PubMed

    Chu, Xiuxiang

    2007-12-24

    The propagation of a cosh-Gaussian beam through an arbitrary ABCD optical system in turbulent atmosphere has been investigated. The analytical expressions for the average intensity at any receiver plane are obtained. As an elementary example, the average intensity and its radius at the image plane of a cosh-Gaussian beam through a thin lens are studied. To show the effects of a lens on the average intensity and the intensity radius of the laser beam in turbulent atmosphere, the properties of a collimated cosh-Gaussian beam and a focused cosh-Gaussian beam for direct propagation in turbulent atmosphere are studied and numerically calculated. The average intensity profiles of a cosh-Gaussian beam through a lens can have a shape similar to that of the initial beam for a longer propagation distance than that of a collimated cosh-Gaussian beam for direct propagation. With the increment in the propagation distance, the average intensity radius at the image plane of a cosh-Gaussian beam through a thin lens will be smaller than that at the focal plane of a focused cosh-Gaussian beam for direct propagation. Meanwhile, the intensity distributions at the image plane of a cosh-Gaussian beam through a lens with different w(0) and Omega(0) are also studied.

  10. Multi-channel automotive night vision system

    NASA Astrophysics Data System (ADS)

    Lu, Gang; Wang, Li-jun; Zhang, Yi

    2013-09-01

    A four-channel automotive night vision system is designed and developed .It is consist of the four active near-infrared cameras and an Mulit-channel image processing display unit,cameras were placed in the automobile front, left, right and rear of the system .The system uses near-infrared laser light source,the laser light beam is collimated, the light source contains a thermoelectric cooler (TEC),It can be synchronized with the camera focusing, also has an automatic light intensity adjustment, and thus can ensure the image quality. The principle of composition of the system is description in detail,on this basis, beam collimation,the LD driving and LD temperature control of near-infrared laser light source,four-channel image processing display are discussed.The system can be used in driver assistance, car BLIS, car parking assist system and car alarm system in day and night.

  11. A Fresnel zone plate collimator: potential and aberrations

    NASA Astrophysics Data System (ADS)

    Menz, Benedikt; Bräuninger, Heinrich; Burwitz, Vadim; Hartner, Gisela; Predehl, Peter

    2015-09-01

    A collimator, that parallelizes an X-ray beam, provides a significant improvement of the metrology to characterize X-ray optics for space instruments at MPE's PANTER X-ray test facility. A Fresnel zone plate was selected as a collimating optic, as it meets a good angular resolution < 0.1n combined with a large active area > 10 cm2. Such an optic is ideally suited to illuminate Silicon Pore Optic (SPO) modules as proposed for ATHENA. This paper provides the theoretic description of such a Fresnel zone plate especially considering resolution and efficiency. Based on the theoretic results the collimator setup performance is analyzed and requirements for fabrication and alignment are calculated.

  12. Conceptual design of hollow electron lenses for beam halo control in the Large Hadron Collider

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stancari, Giulio; Previtali, Valentina; Valishev, Alexander

    Collimation with hollow electron beams is a technique for halo control in high-power hadron beams. It is based on an electron beam (possibly pulsed or modulated in intensity) guided by strong axial magnetic fields which overlaps with the circulating beam in a short section of the ring. The concept was tested experimentally at the Fermilab Tevatron collider using a hollow electron gun installed in one of the Tevatron electron lenses. We are proposing a conceptual design for applying this technique to the Large Hadron Collider at CERN. A prototype hollow electron gun for the LHC was built and tested. Themore » expected performance of the hollow electron beam collimator was based on Tevatron experiments and on numerical tracking simulations. Halo removal rates and enhancements of halo diffusivity were estimated as a function of beam and lattice parameters. Proton beam core lifetimes and emittance growth rates were checked to ensure that undesired effects were suppressed. Hardware specifications were based on the Tevatron devices and on preliminary engineering integration studies in the LHC machine. Required resources and a possible timeline were also outlined, together with a brief discussion of alternative halo-removal schemes and of other possible uses of electron lenses to improve the performance of the LHC.« less

  13. SU-D-206-07: CBCT Scatter Correction Based On Rotating Collimator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, G; Feng, Z; Yin, Y

    2016-06-15

    Purpose: Scatter correction in cone-beam computed tomography (CBCT) has obvious effect on the removal of image noise, the cup artifact and the increase of image contrast. Several methods using a beam blocker for the estimation and subtraction of scatter have been proposed. However, the inconvenience of mechanics and propensity to residual artifacts limited the further evolution of basic and clinical research. Here, we propose a rotating collimator-based approach, in conjunction with reconstruction based on a discrete Radon transform and Tchebichef moments algorithm, to correct scatter-induced artifacts. Methods: A rotating-collimator, comprising round tungsten alloy strips, was mounted on a linear actuator.more » The rotating-collimator is divided into 6 portions equally. The round strips space is evenly spaced on each portion but staggered between different portions. A step motor connected to the rotating collimator drove the blocker to around x-ray source during the CBCT acquisition. The CBCT reconstruction based on a discrete Radon transform and Tchebichef moments algorithm is performed. Experimental studies using water phantom and Catphan504 were carried out to evaluate the performance of the proposed scheme. Results: The proposed algorithm was tested on both the Monte Carlo simulation and actual experiments with the Catphan504 phantom. From the simulation result, the mean square error of the reconstruction error decreases from 16% to 1.18%, the cupping (τcup) from 14.005% to 0.66%, and the peak signal-to-noise ratio increase from 16.9594 to 31.45. From the actual experiments, the induced visual artifacts are significantly reduced. Conclusion: We conducted an experiment on CBCT imaging system with a rotating collimator to develop and optimize x-ray scatter control and reduction technique. The proposed method is attractive in applications where a high CBCT image quality is critical, for example, dose calculation in adaptive radiation therapy. We want to thank Dr. Lei Xing and Dr. Yong Yang in the Stanford University School of Medicine for this work. This work was jointly supported by NSFC (61471226), Natural Science Foundation for Distinguished Young Scholars of Shandong Province (JQ201516), and China Postdoctoral Science Foundation (2015T80739, 2014M551949).« less

  14. Technical Note: Experimental results from a prototype high-field inline MRI-linac

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liney, G. P., E-mail: gary.liney@sswahs.nsw.gov.au

    Purpose: The pursuit of real-time image guided radiotherapy using optimal tissue contrast has seen the development of several hybrid magnetic resonance imaging (MRI)-treatment systems, high field and low field, and inline and perpendicular configurations. As part of a new MRI-linac program, an MRI scanner was integrated with a linear accelerator to enable investigations of a coupled inline MRI-linac system. This work describes results from a prototype experimental system to demonstrate the feasibility of a high field inline MR-linac. Methods: The magnet is a 1.5 T MRI system (Sonata, Siemens Healthcare) was located in a purpose built radiofrequency (RF) cage enablingmore » shielding from and close proximity to a linear accelerator with inline (and future perpendicular) orientation. A portable linear accelerator (Linatron, Varian) was installed together with a multileaf collimator (Millennium, Varian) to provide dynamic field collimation and the whole assembly built onto a stainless-steel rail system. A series of MRI-linac experiments was performed to investigate (1) image quality with beam on measured using a macropodine (kangaroo) ex vivo phantom; (2) the noise as a function of beam state measured using a 6-channel surface coil array; and (3) electron contamination effects measured using Gafchromic film and an electronic portal imaging device (EPID). Results: (1) Image quality was unaffected by the radiation beam with the macropodine phantom image with the beam on being almost identical to the image with the beam off. (2) Noise measured with a surface RF coil produced a 25% elevation of background intensity when the radiation beam was on. (3) Film and EPID measurements demonstrated electron focusing occurring along the centerline of the magnet axis. Conclusions: A proof-of-concept high-field MRI-linac has been built and experimentally characterized. This system has allowed us to establish the efficacy of a high field inline MRI-linac and study a number of the technical challenges and solutions.« less

  15. Optimized Orthovoltage Stereotactic Radiosurgery

    NASA Astrophysics Data System (ADS)

    Fagerstrom, Jessica M.

    Because of its ability to treat intracranial targets effectively and noninvasively, stereotactic radiosurgery (SRS) is a prevalent treatment modality in modern radiation therapy. This work focused on SRS delivering rectangular function dose distributions, which are desirable for some targets such as those with functional tissue included within the target volume. In order to achieve such distributions, this work used fluence modulation and energies lower than those utilized in conventional SRS. In this work, the relationship between prescription isodose and dose gradients was examined for standard, unmodulated orthovoltage SRS dose distributions. Monte Carlo-generated energy deposition kernels were used to calculate 4pi, isocentric dose distributions for a polyenergetic orthovoltage spectrum, as well as monoenergetic orthovoltage beams. The relationship between dose gradients and prescription isodose was found to be field size and energy dependent, and values were found for prescription isodose that optimize dose gradients. Next, a pencil-beam model was used with a Genetic Algorithm search heuristic to optimize the spatial distribution of added tungsten filtration within apertures of cone collimators in a moderately filtered 250 kVp beam. Four cone sizes at three depths were examined with a Monte Carlo model to determine the effects of the optimized modulation compared to open cones, and the simulations found that the optimized cones were able to achieve both improved penumbra and flatness statistics at depth compared to the open cones. Prototypes of the filter designs calculated using mathematical optimization techniques and Monte Carlo simulations were then manufactured and inserted into custom built orthovoltage SRS cone collimators. A positioning system built in-house was used to place the collimator and filter assemblies temporarily in the 250 kVp beam line. Measurements were performed in water using radiochromic film scanned with both a standard white light flatbed scanner as well as a prototype laser densitometry system. Measured beam profiles showed that the modulated beams could more closely approach rectangular function dose profiles compared to the open cones. A methodology has been described and implemented to achieve optimized SRS delivery, including the development of working prototypes. Future work may include the construction of a full treatment platform.

  16. An orbital angular momentum radio communication system optimized by intensity controlled masks effectively: Theoretical design and experimental verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gao, Xinlu; Applied Optics Beijing Area Major Laboratory, Department of Physics, Beijing Normal University, Beijing 100875; Huang, Shanguo, E-mail: shghuang@bupt.edu.cn

    A system of generating and receiving orbital angular momentum (OAM) radio beams, which are collectively formed by two circular array antennas (CAAs) and effectively optimized by two intensity controlled masks, is proposed and experimentally investigated. The scheme is effective in blocking of the unwanted OAM modes and enhancing the power of received radio signals, which results in the capacity gain of system and extended transmission distance of the OAM radio beams. The operation principle of the intensity controlled masks, which can be regarded as both collimator and filter, is feasible and simple to realize. Numerical simulations of intensity and phasemore » distributions at each key cross-sectional plane of the radio beams demonstrate the collimated results. The experimental results match well with the theoretical analysis and the receive distance of the OAM radio beam at radio frequency (RF) 20 GHz is extended up to 200 times of the wavelength of the RF signals, the measured distance is 5 times of the original measured distance. The presented proof-of-concept experiment demonstrates the feasibility of the system.« less

  17. Simulator for beam-based LHC collimator alignment

    NASA Astrophysics Data System (ADS)

    Valentino, Gianluca; Aßmann, Ralph; Redaelli, Stefano; Sammut, Nicholas

    2014-02-01

    In the CERN Large Hadron Collider, collimators need to be set up to form a multistage hierarchy to ensure efficient multiturn cleaning of halo particles. Automatic algorithms were introduced during the first run to reduce the beam time required for beam-based setup, improve the alignment accuracy, and reduce the risk of human errors. Simulating the alignment procedure would allow for off-line tests of alignment policies and algorithms. A simulator was developed based on a diffusion beam model to generate the characteristic beam loss signal spike and decay produced when a collimator jaw touches the beam, which is observed in a beam loss monitor (BLM). Empirical models derived from the available measurement data are used to simulate the steady-state beam loss and crosstalk between multiple BLMs. The simulator design is presented, together with simulation results and comparison to measurement data.

  18. The Los ALamos Neutron Science Center Hydrogen Moderator System

    NASA Astrophysics Data System (ADS)

    Jarmer, J. J.; Knudson, J. N.

    2006-04-01

    At the Los Alamos Neutron Science Center (LANSCE), spallation neutrons are produced by an 800-MeV proton beam interacting with tungsten targets. Gun-barrel-type penetrations through the heavy concrete and steel shielding that surround the targets collimate neutrons to form neutron beams used for scattering experiments. Two liquid hydrogen moderators of one-liter volume each are positioned adjacent to the neutron-production targets. Some of the neutrons that pass through a moderator interact with or scatter from protons in the hydrogen. The neutron-proton interaction reduces the energy or moderates neutrons to lower energies. Lower energy "moderated" neutrons are the most useful for some neutron scattering experiments. We provide a description of the LANSCE hydrogen-moderator system and its cryogenic performance with proton beams of up to 125 micro-amp average current.

  19. Bending self-collimated one-way light by using gyromagnetic photonic crystals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Qing-Bo; Jiangsu Key Construction Laboratory of Modern Measurement Technology and Intelligent System, Huaiyin Normal University, Huaian 223300; Li, Zhen

    2015-12-14

    We theoretically demonstrate that electromagnetic waves can self-collimate and propagate unidirectionally in photonic crystals fabricated using semicylindrical ferrite rods in magnetized states. The parity and time-reversal symmetries of such photonic crystals are broken, resulting in a self-collimated one-way body wave within the photonic crystals. By applying the bias magnetic field in a complex configuration, the self-collimated one-way wave beam can be bent into arbitrary trajectories within the photonic crystal, providing an avenue for controlling wave beams.

  20. Compact 2100 nm laser diode module for next-generation DIRCM

    NASA Astrophysics Data System (ADS)

    Dvinelis, Edgaras; Greibus, Mindaugas; TrinkÅ«nas, Augustinas; NaujokaitÄ--, Greta; Vizbaras, Augustinas; Vizbaras, Dominykas; Vizbaras, Kristijonas

    2017-10-01

    Compact high-power 2100 nm laser diode module for next-generation directional infrared countermeasure (DIRCM) systems is presented. Next-generation DIRCM systems require compact, light-weight and robust laser modules which could provide intense IR light emission capable of disrupting the tracking sensor of heat-seeking missile. Currently used solid-state and fiber laser solutions for mid-IR band are bulky and heavy making them difficult to implement in smaller form-factor DIRCM systems. Recent development of GaSb laser diode technology greatly improved optical output powers and efficiencies of laser diodes working in 1900 - 2450 nm band [1] while also maintaining very attractive size, weight, power consumption and cost characteristics. 2100 nm laser diode module presented in this work performance is based on high-efficiency broad emitting area GaSb laser diode technology. Each laser diode emitter is able to provide 1 W of CW output optical power with working point efficiency up to 20% at temperature of 20 °C. For output beam collimation custom designed fast-axis collimator and slow-axis collimator lenses were used. These lenses were actively aligned and attached using UV epoxy curing. Total 2 emitters stacked vertically were used in 2100 nm laser diode module. Final optical output power of the module goes up to 2 W at temperature of 20 °C. Total dimensions of the laser diode module are 35 x 25 x 16 mm (L x W x H) with a weight of 28 grams. Finally output beam is bore-sighted to mechanical axes of the module housing allowing for easy integration into next-generation DIRCM systems.

  1. Beam shaping to improve the free-electron laser performance at the Linac Coherent Light Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ding, Y.; Bane, K. L. F.; Colocho, W.

    2016-10-27

    A new operating mode has been developed for the Linac Coherent Light Source (LCLS) in which we shape the longitudinal phase space of the electron beam. This mode of operation is realized using a horizontal collimator located in the middle of the first bunch compressor to truncate the head and tail of the beam. With this method, the electron beam longitudinal phase space and current profile are reshaped, and improvement in lasing performance can be realized. As a result, we present experimental studies at the LCLS of the beam shaping effects on the free-electron laser performance.

  2. Fiber optic engine for micro projection display.

    PubMed

    Arabi, Hesam Edin; An, Sohee; Oh, Kyunghwan

    2010-03-01

    A novel compact optical engine for a micro projector display is experimentally demonstrated, which is composed of RGB light sources, a tapered 3 x 1 Fiber Optic Color Synthesizer (FOCS) along with a fiberized ball-lens, and a two dimensional micro electromechanical scanning mirror. In the proposed optical engine, we successfully employed an all-fiber beam shaping technique combining optical fiber taper and fiberized ball lens that can render a narrow beam and enhance the resolution of the screened image in the far field. Optical performances of the proposed device assembly are investigated in terms of power loss, collimating strength of the collimator assembly, and color gamut of the output.

  3. SU-G-TeP4-12: Individual Beam QA for a Robotic Radiosurgery System Using a Scintillator Cone

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McGuinness, C; Descovich, M; Sudhyadhom, A

    2016-06-15

    Purpose: The targeting accuracy of the Cyberknife system is measured by end-to-end tests delivering multiple isocentric beams to a point in space. While the targeting accuracy of two representative beams can be determined by a Winston-Lutz-type test, no test is available today to determine the targeting accuracy of each clinical beam. We used a scintillator cone to measure the accuracy of each individual beam. Methods: The XRV-124 from Logos Systems Int’l is a scintillator cone with an imaging system that is able to measure individual beam vectors and a resulting error between planned and measured beam coordinates. We measured themore » targeting accuracy of isocentric and non-isocentric beams for a number of test cases using the Iris and the fixed collimator. The average difference between plan and measured beam position was 0.8–1.2mm across the collimator sizes and plans considered here. The max error for a single beam was 2.5mm for the isocentric plans, and 1.67mm for the non-isocentric plans. The standard deviation of the differences was 0.5mm or less. Conclusion: The CyberKnife System is specified to have an overall targeting accuracy for static targets of less than 0.95mm. In E2E tests using the XRV124 system we measure average beam accuracy between 0.8 to 1.23mm, with maximum of 2.5mm. We plan to investigate correlations between beam position error and robot position, and to quantify the effect of beam position errors on patient specific plans. Martina Descovich has received research support and speaker honoraria from Accuray.« less

  4. Beam Loss Monitoring for LHC Machine Protection

    NASA Astrophysics Data System (ADS)

    Holzer, Eva Barbara; Dehning, Bernd; Effnger, Ewald; Emery, Jonathan; Grishin, Viatcheslav; Hajdu, Csaba; Jackson, Stephen; Kurfuerst, Christoph; Marsili, Aurelien; Misiowiec, Marek; Nagel, Markus; Busto, Eduardo Nebot Del; Nordt, Annika; Roderick, Chris; Sapinski, Mariusz; Zamantzas, Christos

    The energy stored in the nominal LHC beams is two times 362 MJ, 100 times the energy of the Tevatron. As little as 1 mJ/cm3 deposited energy quenches a magnet at 7 TeV and 1 J/cm3 causes magnet damage. The beam dumps are the only places to safely dispose of this beam. One of the key systems for machine protection is the beam loss monitoring (BLM) system. About 3600 ionization chambers are installed at likely or critical loss locations around the LHC ring. The losses are integrated in 12 time intervals ranging from 40 μs to 84 s and compared to threshold values defined in 32 energy ranges. A beam abort is requested when potentially dangerous losses are detected or when any of the numerous internal system validation tests fails. In addition, loss data are used for machine set-up and operational verifications. The collimation system for example uses the loss data for set-up and regular performance verification. Commissioning and operational experience of the BLM are presented: The machine protection functionality of the BLM system has been fully reliable; the LHC availability has not been compromised by false beam aborts.

  5. Modulation transfer function assessment in parallel beam and fan beam collimators with square and cylindrical holes.

    PubMed

    Khorshidi, Abdollah; Ashoor, Mansour

    2014-05-01

    This study investigates modulation transfer function (MTF) in parallel beam (PB) and fan beam (FB) collimators using the Monte Carlo method with full width at half maximum (FWHM), square and circular-shaped holes, and scatter and penetration (S + P) components. A regulation similar to the lead-to-air ratio was used for both collimators to estimate output data. The hole pattern was designed to compare FB by PB parameters. The radioactive source in air and in a water phantom placed in front of the collimators was simulated using MCNP5 code. The test results indicated that the square holes in PB (PBs) had better FWHM than did the cylindrical (PBc) holes. In contrast, the cylindrical holes in the FB (FBc) had better FWHM than the square holes. In general, the resolution of FBc was better than that of the PBc in air and scatter mediums. The S + P decreased for all collimators as the distance from the source to the collimator surface (z) increased. The FBc had a lower S + P than FBs, but PBc had a higher S + P than PBs. Of the FB and PB collimators with the identical hole shapes, PBs had a smaller S + P than FBs, and FBc had a smaller S + P than PBc. The MTF value for the FB was greater than for the PB and had increased spatial frequency; the FBc had higher MTF than the FBs and PB collimators. Estimating the FB using PB parameters and diverse hole shapes may be useful in collimator design to improve the resolution and efficiency of SPECT images.

  6. Microfocus/Polycapillary-Optic Crystallographic X-Ray System

    NASA Technical Reports Server (NTRS)

    Joy, Marshall; Gubarev, Mikhail; Ciszak, Ewa

    2005-01-01

    A system that generates an intense, nearly collimated, nearly monochromatic, small-diameter x-ray beam has been developed for use in macromolecular crystallography. A conventional x-ray system for macromolecular crystallography includes a rotating-anode x-ray source, which is massive (.500 kg), large (approximately 2 by 2 by 1 m), and power-hungry (between 2 and 18 kW). In contrast, the present system generates a beam of the required brightness from a microfocus source, which is small and light enough to be mounted on a laboratory bench, and operates at a power level of only tens of watts. The figure schematically depicts the system as configured for observing x-ray diffraction from a macromolecular crystal. In addition to the microfocus x-ray source, the system includes a polycapillary optic . a monolithic block (typically a bundle of fused glass tubes) that contains thousands of straight or gently curved capillary channels, along which x-rays propagate with multiple reflections. This particular polycapillary optic is configured to act as a collimator; the x-ray beam that emerges from its output face consists of quasi-parallel subbeams with a small angular divergence and a diameter comparable to the size of a crystal to be studied. The gap between the microfocus x-ray source and the input face of the polycapillary optic is chosen consistently with the focal length of the polycapillary optic and the need to maximize the solid angle subtended by the optic in order to maximize the collimated x-ray flux. The spectrum from the source contains a significant component of Cu K (photon energy is 8.08 keV) radiation. The beam is monochromatized (for Cu K ) by a nickel filter 10 m thick. In a test, this system was operated at a power of 40 W (current of 897 A at an accelerating potential of 45 kV), with an anode x-ray spot size of 41+/-2 microns. Also tested, in order to provide a standard for comparison, was a commercial rotating-anode x-ray crystallographic system with a pyrolytic graphite monochromator and a 250-micron pinhole collimator, operating at a power of 3.15 kW (current of 70 mA at an accelerating potential of 45 kV). The flux of collimated Cu K radiation in this system was found to be approximately 16 times that in the rotatinganode system. Data on x-ray diffraction from crystals of tetragonal form of lysozyme (protein) in this system were found to be of high quality and to be reducible by use of standard crystallographic software.

  7. A design of a high speed dual spectrometer by single line scan camera

    NASA Astrophysics Data System (ADS)

    Palawong, Kunakorn; Meemon, Panomsak

    2018-03-01

    A spectrometer that can capture two orthogonal polarization components of s light beam is demanded for polarization sensitive imaging system. Here, we describe the design and implementation of a high speed spectrometer for simultaneous capturing of two orthogonal polarization components, i.e. vertical and horizontal components, of light beam. The design consists of a polarization beam splitter, two polarization-maintain optical fibers, two collimators, a single line-scan camera, a focusing lens, and a reflection blaze grating. The alignment of two beam paths was designed to be symmetrically incident on the blaze side and reverse blaze side of reflection grating, respectively. The two diffracted beams were passed through the same focusing lens and focused on the single line-scan sensors of a CMOS camera. The two spectra of orthogonal polarization were imaged on 1000 pixels per spectrum. With the proposed setup, the amplitude and shape of the two detected spectra can be controlled by rotating the collimators. The technique for optical alignment of spectrometer will be presented and discussed. The two orthogonal polarization spectra can be simultaneously captured at a speed of 70,000 spectra per second. The high speed dual spectrometer can simultaneously detected two orthogonal polarizations, which is an important component for the development of polarization-sensitive optical coherence tomography. The performance of the spectrometer have been measured and analyzed.

  8. High stability wavefront reference source

    DOEpatents

    Feldman, M.; Mockler, D.J.

    1994-05-03

    A thermally and mechanically stable wavefront reference source which produces a collimated output laser beam is disclosed. The output beam comprises substantially planar reference wavefronts which are useful for aligning and testing optical interferometers. The invention receives coherent radiation from an input optical fiber, directs a diverging input beam of the coherent radiation to a beam folding mirror (to produce a reflected diverging beam), and collimates the reflected diverging beam using a collimating lens. In a class of preferred embodiments, the invention includes a thermally and mechanically stable frame comprising rod members connected between a front end plate and a back end plate. The beam folding mirror is mounted on the back end plate, and the collimating lens mounted to the rods between the end plates. The end plates and rods are preferably made of thermally stable metal alloy. Preferably, the input optical fiber is a single mode fiber coupled to an input end of a second single mode optical fiber that is wound around a mandrel fixedly attached to the frame of the apparatus. The output end of the second fiber is cleaved so as to be optically flat, so that the input beam emerging therefrom is a nearly perfect diverging spherical wave. 7 figures.

  9. High stability wavefront reference source

    DOEpatents

    Feldman, Mark; Mockler, Daniel J.

    1994-01-01

    A thermally and mechanically stable wavefront reference source which produces a collimated output laser beam. The output beam comprises substantially planar reference wavefronts which are useful for aligning and testing optical interferometers. The invention receives coherent radiation from an input optical fiber, directs a diverging input beam of the coherent radiation to a beam folding mirror (to produce a reflected diverging beam), and collimates the reflected diverging beam using a collimating lens. In a class of preferred embodiments, the invention includes a thermally and mechanically stable frame comprising rod members connected between a front end plate and a back end plate. The beam folding mirror is mounted on the back end plate, and the collimating lens mounted to the rods between the end plates. The end plates and rods are preferably made of thermally stable metal alloy. Preferably, the input optical fiber is a single mode fiber coupled to an input end of a second single mode optical fiber that is wound around a mandrel fixedly attached to the frame of the apparatus. The output end of the second fiber is cleaved so as to be optically flat, so that the input beam emerging therefrom is a nearly perfect diverging spherical wave.

  10. Polarization/Spatial Combining of Laser-Diode Pump Beams

    NASA Technical Reports Server (NTRS)

    Gelsinger, Paul; Liu, Duncan

    2008-01-01

    A breadboard version of an optical beam combiner is depicted which make it possible to use the outputs of any or all of four multimode laser diodes to pump a non-planar ring oscillator (NPRO) laser. The output of each laser diode has a single-mode profile in the meridional plane containing an axis denoted the 'fast' axis and a narrower multimode profile in the orthogonal meridional plane, which contains an axis denoted the 'slow' axis and a narrower multimode profile in the orthogonal meridional plane, which contains an axis denoted the 'slow' axis. One of the purposes served by the beam-combining optics is to reduce the fast-axis numerical aperture (NA) of the laser-diode output to match the NA of the optical fiber. Along the slow axis, the unmodified laser-diode NA is already well matched to the fiber optic NA, so no further slow-axis beam shaping is needed. In this beam combiner, the laser-diode outputs are collimated by aspherical lenses, then half-wave plates and polarizing beam splitters are used to combine the four collimated beams into two beams. Spatial combination of the two beams and coupling into the optical fiber is effected by use of anamorphic prisms, mirrors, and a focusing lens. The anamorphic prisms are critical elements in the NA-matching scheme, in that they reduce the fast-axis beam width to 1/6 of its original values. Inasmuch as no slow-axis beam shaping is needed, the collimating and focusing lenses are matched for 1:1 iumaging. Because these lenses are well corrected for infinite conjugates the combiner offers diffraction-limited performance along both the fast and slow axes.

  11. Development of a multi-knife-edge slit collimator for prompt gamma ray imaging during proton beam cancer therapy

    NASA Astrophysics Data System (ADS)

    Ready, John Francis, III

    Proton beam usage to treat cancer has recently experienced rapid growth, as it offers the ability to target dose delivery in a patient more precisely than traditional x-ray treatment methods. Protons stop within the patient, delivering the maximum dose at the end of their track--a phenomenon described as the Bragg peak. However, because a large dose is delivered to a small volume, proton therapy is very sensitive to errors in patient setup and treatment planning calculations. Additionally, because all primary beam particles stop in the patient, there is no direct information available to verify dose delivery. These factors contribute to the range uncertainty in proton therapy, which ultimately hinders its clinical usefulness. A reliable method of proton range verification would allow the clinician to fully utilize the precise dose delivery of the Bragg peak. Several methods to verify proton range detect secondary emissions, especially prompt gamma ray (PG) emissions. However, detection of PGs is challenging due to their high energy (2-10 MeV) and low attenuation coefficients, which limit PG interactions in materials. Therefore, detection and collimation methods must be specifically designed for prompt gamma ray imaging (PGI) applications. In addition, production of PGs relies on delivering a dose of radiation to the patient. Ideally, verification of the Bragg peak location exposes patients to a minimal dose, thus limiting the PG counts available to the imaging system. An additional challenge for PGI is the lack of accurate simulation models, which limit the study of PG production characteristics and the relationship between PG distribution and dose delivery. Specific limitations include incorrect modeling of the reaction cross sections, gamma emission yields, and angular distribution of emission for specific photon energies. While simulations can still be valuable assets in designing a system to detect and image PGs, until new models are developed and incorporated into Monte Carlo simulation packages, simulations cannot be used to study the production and location of PG emissions during proton therapy. This work presents a novel system to image PGs emitted during proton therapy to verify proton beam range. The imaging system consists of a multi-slit collimator paired with a position-sensitive LSO scintillation detector. This innovative design is the first collimated imaging system to implement two-dimensional (2-D) imaging for PG proton beam range verification, while also providing a larger field of view than compared to single-slit collimator systems. Other, uncollimated imaging systems have been explored for PGI applications, such as Compton cameras. However, Compton camera designs are severely limited by counting rate capabilities. A recent Compton camera study reported count rate capability of about 5 kHz. However, at a typical clinical beam current of 1.0 nA, the estimated PG emission rate would be 6 x 108 per second. After accounting for distance to the detector and interaction efficiencies, the detection system will still be overwhelmed with counts in the MHz range, causing false coincidences and hindering the operation of the imaging system. Initial measurements using 50 MeV protons demonstrated the ability of our system to reconstruct 2-D PG distributions at clinical beam currents. A Bragg peak localization precision of 1 mm (2sigma) was achieved with delivery of (1.7 +/- 0.8) x 108 protons into a PMMA target, suggesting the ability of the system to detect relative shifts in proton range while delivering fewer protons than used in a typical treatment fraction. This is key, as the ideal system allows the clinician to verify proton range when delivering only a small portion of the prescribed dose, preventing the mistreatment of the patient. Additionally, the absolute position of the Bragg peak was identified to within 1.6 mm (2sigma) with 5.6 x 1010 protons delivered. These promising results warrant further investigation and system optimization for clinical implementation. While further measurements at clinical beam energy levels will be required to verify system performance, these preliminary results provide evidence that 2-D image reconstruction, with 1-2 mm accuracy, is possible with this design. Implementing such a system in the clinical setting would greatly improve proton therapy cancer treatment outcomes.

  12. Measurement system and model for simultaneously measuring 6DOF geometric errors.

    PubMed

    Zhao, Yuqiong; Zhang, Bin; Feng, Qibo

    2017-09-04

    A measurement system to simultaneously measure six degree-of-freedom (6DOF) geometric errors is proposed. The measurement method is based on a combination of mono-frequency laser interferometry and laser fiber collimation. A simpler and more integrated optical configuration is designed. To compensate for the measurement errors introduced by error crosstalk, element fabrication error, laser beam drift, and nonparallelism of two measurement beam, a unified measurement model, which can improve the measurement accuracy, is deduced and established using the ray-tracing method. A numerical simulation using the optical design software Zemax is conducted, and the results verify the correctness of the model. Several experiments are performed to demonstrate the feasibility and effectiveness of the proposed system and measurement model.

  13. Performance characterization of a new CZT-based preclinical SPECT system: a comparative study of different collimators

    NASA Astrophysics Data System (ADS)

    Yu, A. R.; Park, S.-J.; Choi, Y. Y.; Kim, K. M.; Kim, H.-J.

    2015-09-01

    Triumph X-SPECT is a newly released CZT-based preclinical small-animal SPECT system with interchangeable collimators. The purpose of this work was to evaluate and systematically compare the imaging performances of three different collimators in the CZT-based preclinical small-animal system: a single-pinhole collimator (SPH), a multi-pinhole collimator (MPH) and a parallel-hole collimator. We measured the spatial resolutions and sensitivities of the three collimators with 99mTc sources, considering three distinct energy window widths (5, 10, and 20%), and used the NEMA NU4-2008 Image Quality phantom to test the imaging performance of the three collimators in terms of uniformity and spill-over ratio (SOR) for each energy window. With a 10% energy window width at a radius of rotation (ROR) of 30 mm, the system resolution of the SPH, MPH and parallel-hole collimators was 0.715, 0.855 and 3.270 mm FWHM, respectively. For the same energy window, the sensitivity of the system with SPH, MPH and parallel-hole collimators was 32.860, 152.514 and 49.205 counts/sec/MBq at a 100 mm source-to-detector distance and 6.790, 33.376 and 49.038 counts/sec/MBq at a 130 mm source-to-detector distance, respectively. The image noise and SORair for the three collimators were 20.137, 12.278 and 11.232 (%STDunif) and 0.106, 0.140 and 0.161, respectively. Overall, the results show that the SPH had better spatial resolution than the other collimators. The MPH had the highest sensitivity at 100 mm source-to-collimator distance, and the parallel-hole collimator had the highest sensitivity at 130 mm-source-to-detector distance. Therefore, the proper collimator for Triumph X-SPECT system must be determined by the task. These results provide valuable reference data and insight into the imaging performance of various collimators in CZT-based preclinical small-animal SPECT.

  14. Electron Lenses for the Large Hadron Collider

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stancari, Giulio; Valishev, Alexander; Bruce, Roderik

    Electron lenses are pulsed, magnetically confined electron beams whose current-density profile is shaped to obtain the desired effect on the circulating beam. Electron lenses were used in the Fermilab Tevatron collider for bunch-by-bunch compensation of long-range beam-beam tune shifts, for removal of uncaptured particles in the abort gap, for preliminary experiments on head-on beam-beam compensation, and for the demonstration of halo scraping with hollow electron beams. Electron lenses for beam-beam compensation are being commissioned in RHIC at BNL. Within the US LHC Accelerator Research Program and the European HiLumi LHC Design Study, hollow electron beam collimation was studied as anmore » option to complement the collimation system for the LHC upgrades. This project is moving towards a technical design in 2014, with the goal to build the devices in 2015-2017, after resuming LHC operations and re-assessing needs and requirements at 6.5 TeV. Because of their electric charge and the absence of materials close to the proton beam, electron lenses may also provide an alternative to wires for long-range beam-beam compensation in LHC luminosity upgrade scenarios with small crossing angles.« less

  15. Physical properties of new collimator cone system for stereotactic radiation therapy developed in samsung medical center.

    PubMed

    Kim, D Y; Ahn, Y C; Oh, D G; Choi, D R; Ju, S G; Yeo, I H; Huh, S J

    2000-09-01

    A new collimator cone system has been developed at the Samsung Medical Center that overcomes some of the limitations of present commercially supplied collimator cones. The physical properties of the newly developed cone system are described in this report. The new cones have relatively larger aperture sizes (3.0-7.0 cm in diameter) and are 16 cm in length. Each new cone is fabricated with cerrobend alloy melted and poured into a stainless steel housing that is permanently fixed to a mounting plate. The mounting plate of the new cone is designed to insert into the wedge mount slot of the gantry head. The mechanical accuracy of the central axis of the cone pointing to the isocenter was tested using film, a steel ball positioned at the isocenter by the mechanical isocenter device. For the evaluation of beam flatness and penumbra, off-axis ratios at 5 cm depth were measured by film dosimetry using polystyrene phantom. The average error of the mechanical isocenter was 0.27 mm (+/- 0.16 mm). The beam flatness was excellent in the central region of the beam, and the average penumbra width was 3.35 mm (+/- 0.25 mm). The new cone design has more clearance between the patient's head and the gantry, and can more easily be removed from the gantry head because it slides in and out of the wedge slot. This facilitates changing cone sizes during one treatment session, and makes the process of double exposure port films easier. A new collimator cone system for stereotactic radiation therapy has been developed. The mechanical accuracy and physical properties are satisfactory for clinical use, and the new design permits a wider range of clinical applications for stereotactic radiation therapy.

  16. Readiness of the ATLAS detector: Performance with the first beam and cosmic data

    NASA Astrophysics Data System (ADS)

    Pastore, F.

    2010-05-01

    During 2008 the ATLAS experiment went through an intense period of preparation to have the detector fully commissioned for the first beam period. In about 30 h of beam time available to ATLAS in 2008 the systems went through a rapid setup sequence, from successfully recording the first bunch ever reaching ATLAS, to setting up the timing of the trigger system synchronous to the incoming single beams. The so-called splash events were recorded, where the beam was stopped on a collimator 140 m upstream of ATLAS, showering the experiment with millions of particles per beam shot. These events were found to be extremely useful for timing setup. After the stop of the beam operation, the experiment went through an extensive cosmic ray data taking campaign, recording more than 500 million cosmic ray events. These events have been used to make significant progress on the calibration and alignment of the detector. This paper describes the commissioning programme and the results obtained from both the single beam data and the cosmic data recorded in 2008.

  17. Design and optimization of an energy degrader with a multi-wedge scheme based on Geant4

    NASA Astrophysics Data System (ADS)

    Liang, Zhikai; Liu, Kaifeng; Qin, Bin; Chen, Wei; Liu, Xu; Li, Dong; Xiong, Yongqian

    2018-05-01

    A proton therapy facility based on an isochronous superconducting cyclotron is under construction in Huazhong University of Science and Technology (HUST). To meet the clinical requirements, an energy degrader is essential in the beamline to modulate the fixed beam energy extracted from the cyclotron. Because of the multiple Coulomb scattering in the degrader, the beam emittance and the energy spread will be considerably increased during the energy degradation process. Therefore, a set of collimators is designed to restrict the increase in beam emittance after the energy degradation. The energy spread will be reduced in the following beam line which is not discussed in this paper. In this paper, the design considerations of an energy degrader and collimators are introduced, and the properties of the degrader material, degrader structure and the initial beam parameters are discussed using the Geant4 Monte-Carlo toolkit, with the main purpose of improving the overall performance of the degrader by multiple parameter optimization.

  18. Design of a radiation facility for very small specimens used in radiobiology studies

    NASA Astrophysics Data System (ADS)

    Rodriguez, Manuel; Jeraj, Robert

    2008-06-01

    A design of a radiation facility for very small specimens used in radiobiology is presented. This micro-irradiator has been primarily designed to irradiate partial bodies in zebrafish embryos 3-4 mm in length. A miniature x-ray, 50 kV photon beam, is used as a radiation source. The source is inserted in a cylindrical brass collimator that has a pinhole of 1.0 mm in diameter along the central axis to produce a pencil photon beam. The collimator with the source is attached underneath a computer-controlled movable table which holds the specimens. Using a 45° tilted mirror, a digital camera, connected to the computer, takes pictures of the specimen and the pinhole collimator. From the image provided by the camera, the relative distance from the specimen to the pinhole axis is calculated and coordinates are sent to the movable table to properly position the samples in the beam path. Due to its monitoring system, characteristic of the radiation beam, accuracy and precision of specimen positioning, and automatic image-based specimen recognition, this radiation facility is a suitable tool to irradiate partial bodies in zebrafish embryos, cell cultures or any other small specimen used in radiobiology research.

  19. CONTINUOUS ABORT GAP CLEANING AT RHIC.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DREES,A.FLILLER,R.III.FU,W.MICHNOFF,R.

    2004-07-05

    Since the RHIC Au-Au run in the year 2001 the 200 MHz cavity system was used at storage and a 28 MHz system during injection and acceleration. The rebucketing procedure potentially causes a higher debunching rate of heavy ion beams in addition to amplifying debunching due to other mechanisms. At the end of a four hour store, debunched beam can easily account for more than 50% of the total beam intensity. This effect is even stronger with the achieved high intensities of the RHIC Au-Au run in 2004. A beam abort at the presence of a lot of debunched beammore » bears the risk of magnet quenching and experimental detector damage due to uncontrolled beam losses. Thus it is desirable to avoid any accumulation of debunched beam from the beginning of each store, in particular to anticipate cases of unscheduled beam aborts due to a system failure. A combination of a fast transverse kickers and the new 2-stage copper collimator system are used to clean the abort gap continuously throughout the store with a repetition rate of 1 Hz. This report gives. an overview of the new gap cleaning procedure and the achieved performance.« less

  20. Method for obtaining a collimated near-unity aspect ratio output beam from a DFB-GSE laser with good beam quality.

    PubMed

    Liew, S K; Carlson, N W

    1992-05-20

    A simple method for obtaining a collimated near-unity aspect ratio output beam from laser sources with extremely large (> 100:1) aspect ratios is demonstrated by using a distributed-feedback grating-surfaceemitting laser. Far-field power-in-the-bucket measurements of the laser indicate good beam quality with a high Strehl ratio.

  1. TU-H-BRC-05: Stereotactic Radiosurgery Optimized with Orthovoltage Beams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fagerstrom, J; Culberson, W; Bender, E

    2016-06-15

    Purpose: To achieve improved stereotactic radiosurgery (SRS) dose distributions using orthovoltage energy fluence modulation with inverse planning optimization techniques. Methods: A pencil beam model was used to calculate dose distributions from the institution’s orthovoltage unit at 250 kVp. Kernels for the model were derived using Monte Carlo methods as well as measurements with radiochromic film. The orthovoltage photon spectra, modulated by varying thicknesses of attenuating material, were approximated using open-source software. A genetic algorithm search heuristic routine was used to optimize added tungsten filtration thicknesses to approach rectangular function dose distributions at depth. Optimizations were performed for depths of 2.5,more » 5.0, and 7.5 cm, with cone sizes of 8, 10, and 12 mm. Results: Circularly-symmetric tungsten filters were designed based on the results of the optimization, to modulate the orthovoltage beam across the aperture of an SRS cone collimator. For each depth and cone size combination examined, the beam flatness and 80–20% and 90–10% penumbrae were calculated for both standard, open cone-collimated beams as well as for the optimized, filtered beams. For all configurations tested, the modulated beams were able to achieve improved penumbra widths and flatness statistics at depth, with flatness improving between 33 and 52%, and penumbrae improving between 18 and 25% for the modulated beams compared to the unmodulated beams. Conclusion: A methodology has been described that may be used to optimize the spatial distribution of added filtration material in an orthovoltage SRS beam to result in dose distributions at depth with improved flatness and penumbrae compared to standard open cones. This work provides the mathematical foundation for a novel, orthovoltage energy fluence-modulated SRS system.« less

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liang, Bin; Li, Yongbao; Liu, Bo

    Purpose: CyberKnife system is initially equipped with fixed circular cones for stereotactic radiosurgery. Two dose calculation algorithms, Ray-Tracing and Monte Carlo, are available in the supplied treatment planning system. A multileaf collimator system was recently introduced in the latest generation of system, capable of arbitrarily shaped treatment field. The purpose of this study is to develop a model based dose calculation algorithm to better handle the lateral scatter in an irregularly shaped small field for the CyberKnife system. Methods: A pencil beam dose calculation algorithm widely used in linac based treatment planning system was modified. The kernel parameters and intensitymore » profile were systematically determined by fitting to the commissioning data. The model was tuned using only a subset of measured data (4 out of 12 cones) and applied to all fixed circular cones for evaluation. The root mean square (RMS) of the difference between the measured and calculated tissue-phantom-ratios (TPRs) and off-center-ratio (OCR) was compared. Three cone size correction techniques were developed to better fit the OCRs at the penumbra region, which are further evaluated by the output factors (OFs). The pencil beam model was further validated against measurement data on the variable dodecagon-shaped Iris collimators and a half-beam blocked field. Comparison with Ray-Tracing and Monte Carlo methods was also performed on a lung SBRT case. Results: The RMS between the measured and calculated TPRs is 0.7% averaged for all cones, with the descending region at 0.5%. The RMSs of OCR at infield and outfield regions are both at 0.5%. The distance to agreement (DTA) at the OCR penumbra region is 0.2 mm. All three cone size correction models achieve the same improvement in OCR agreement, with the effective source shift model (SSM) preferred, due to their ability to predict more accurately the OF variations with the source to axis distance (SAD). In noncircular field validation, the pencil beam calculated results agreed well with the film measurement of both Iris collimators and the half-beam blocked field, fared much better than the Ray-Tracing calculation. Conclusions: The authors have developed a pencil beam dose calculation model for the CyberKnife system. The dose calculation accuracy is better than the standard linac based system because the model parameters were specifically tuned to the CyberKnife system and geometry correction factors. The model handles better the lateral scatter and has the potential to be used for the irregularly shaped fields. Comprehensive validations on MLC equipped system are necessary for its clinical implementation. It is reasonably fast enough to be used during plan optimization.« less

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Jungho; Shi, Xianbo; Casa, Diego

    Advances in resonant inelastic X-ray scattering (RIXS) have come in lockstep with improvements in energy resolution. Currently, the best energy resolution at the IrL 3-edge stands at ~25 meV, which is achieved using a diced Si(844) spherical crystal analyzer. However, spherical analyzers are limited by their intrinsic reflection width. A novel analyzer system using multiple flat crystals provides a promising way to overcome this limitation. For the present design, an energy resolution at or below 10 meV was selected. Recognizing that the angular acceptance of flat crystals is severely limited, a collimating element is essential to achieve the necessary solid-anglemore » acceptance. For this purpose, a laterally graded, parabolic, multilayer Montel mirror was designed for use at the IrL 3-absorption edge. It provides an acceptance larger than 10 mrad, collimating the reflected X-ray beam to smaller than 100 µrad, in both vertical and horizontal directions. The performance of this mirror was studied at beamline 27-ID at the Advanced Photon Source. X-rays from a diamond (111) monochromator illuminated a scattering source of diameter 5 µm, generating an incident beam on the mirror with a well determined divergence of 40 mrad. A flat Si(111) crystal after the mirror served as the divergence analyzer. From X-ray measurements, ray-tracing simulations and optical metrology results, it was established that the Montel mirror satisfied the specifications of angular acceptance and collimation quality necessary for a high-resolution RIXS multi-crystal analyzer system.« less

  4. Scanned Image Projection System Employing Intermediate Image Plane

    NASA Technical Reports Server (NTRS)

    DeJong, Christian Dean (Inventor); Hudman, Joshua M. (Inventor)

    2014-01-01

    In imaging system, a spatial light modulator is configured to produce images by scanning a plurality light beams. A first optical element is configured to cause the plurality of light beams to converge along an optical path defined between the first optical element and the spatial light modulator. A second optical element is disposed between the spatial light modulator and a waveguide. The first optical element and the spatial light modulator are arranged such that an image plane is created between the spatial light modulator and the second optical element. The second optical element is configured to collect the diverging light from the image plane and collimate it. The second optical element then delivers the collimated light to a pupil at an input of the waveguide.

  5. Aberration-free intraocular lenses - What does this really mean?

    PubMed

    Langenbucher, Achim; Schröder, Simon; Cayless, Alan; Eppig, Timo

    2017-09-01

    So-called aberration-free intraocular lenses (IOLs) are well established in modern cataract surgery. Usually, they are designed to perfectly refract a collimated light beam onto the focal point. We show how much aberration can be expected with such an IOL in a convergent light beam such as that found anterior to the human cornea. Additionally, the aberration in a collimated beam is estimated for an IOL that has no aberrations in the convergent beam. The convergent beam is modelled as the pencil of rays corresponding to the spherical wavefront resulting from a typical corneal power of 43m -1 . The IOLs are modelled as infinitely thin phase plates with 20m -1 optical power placed 5mm behind the cornea. Their aberrations are reported in terms of optical path length difference and longitudinal spherical aberration (LSA) of the marginal rays, as well as nominal spherical aberration (SA) calculated based on a Zernike representation of the wavefront-error at the corneal plane within a 6mm aperture. The IOL designed to have no aberrations in a collimated light beam has an optical path length difference of -1.8μm, and LSA of 0.15m -1 in the convergent beam of a typical eye. The corresponding nominal SA is 0.065μm. The IOL designed to have no aberrations in a convergent light beam has an optical path length difference of 1.8μm, and LSA of -0.15m -1 in the collimated beam. An IOL designed to have no aberrations in a collimated light beam will increase the SA of a patient's eye after implantation. Copyright © 2017. Published by Elsevier GmbH.

  6. On isocentre adjustment and quality control in linear accelerator based radiosurgery with circular collimators and room lasers.

    PubMed

    Treuer, H; Hoevels, M; Luyken, K; Gierich, A; Kocher, M; Müller, R P; Sturm, V

    2000-08-01

    We have developed a densitometric method for measuring the isocentric accuracy and the accuracy of marking the isocentre position for linear accelerator based radiosurgery with circular collimators and room lasers. Isocentric shots are used to determine the accuracy of marking the isocentre position with room lasers and star shots are used to determine the wobble of the gantry and table rotation movement, the effect of gantry sag, the stereotactic collimator alignment, and the minimal distance between gantry and table rotation axes. Since the method is based on densitometric measurements, beam spot stability is implicitly tested. The method developed is also suitable for quality assurance and has proved to be useful in optimizing isocentric accuracy. The method is simple to perform and only requires a film box and film scanner for instrumentation. Thus, the method has the potential to become widely available and may therefore be useful in standardizing the description of linear accelerator based radiosurgical systems.

  7. Monte Carlo simulation of a compact microbeam radiotherapy system based on carbon nanotube field emission technology.

    PubMed

    Schreiber, Eric C; Chang, Sha X

    2012-08-01

    Microbeam radiation therapy (MRT) is an experimental radiotherapy technique that has shown potent antitumor effects with minimal damage to normal tissue in animal studies. This unique form of radiation is currently only produced in a few large synchrotron accelerator research facilities in the world. To promote widespread translational research on this promising treatment technology we have proposed and are in the initial development stages of a compact MRT system that is based on carbon nanotube field emission x-ray technology. We report on a Monte Carlo based feasibility study of the compact MRT system design. Monte Carlo calculations were performed using EGSnrc-based codes. The proposed small animal research MRT device design includes carbon nanotube cathodes shaped to match the corresponding MRT collimator apertures, a common reflection anode with filter, and a MRT collimator. Each collimator aperture is sized to deliver a beam width ranging from 30 to 200 μm at 18.6 cm source-to-axis distance. Design parameters studied with Monte Carlo include electron energy, cathode design, anode angle, filtration, and collimator design. Calculations were performed for single and multibeam configurations. Increasing the energy from 100 kVp to 160 kVp increased the photon fluence through the collimator by a factor of 1.7. Both energies produced a largely uniform fluence along the long dimension of the microbeam, with 5% decreases in intensity near the edges. The isocentric dose rate for 160 kVp was calculated to be 700 Gy∕min∕A in the center of a 3 cm diameter target. Scatter contributions resulting from collimator size were found to produce only small (<7%) changes in the dose rate for field widths greater than 50 μm. Dose vs depth was weakly dependent on filtration material. The peak-to-valley ratio varied from 10 to 100 as the separation between adjacent microbeams varies from 150 to 1000 μm. Monte Carlo simulations demonstrate that the proposed compact MRT system design is capable of delivering a sufficient dose rate and peak-to-valley ratio for small animal MRT studies.

  8. Method and apparatus for reducing coherence of high-power laser beams

    DOEpatents

    Moncur, Norman K.; Mayer, Frederick J.

    1978-01-01

    Method and apparatus for reducing the coherence and for smoothing the power density profile of a collimated high-power laser beam in which the beam is focused at a point on the surface of a target fabricated of material having a low atomic number. The initial portion of the focused beam heats the material to form a hot reflective plasma at the material surface. The remaining, major portion of the focused beam is reflected by the plasma and recollected to form a collimated beam having reduced beam coherence.

  9. Portable biochip scanner device

    DOEpatents

    Perov, Alexander; Sharonov, Alexei; Mirzabekov, Andrei D.

    2002-01-01

    A portable biochip scanner device used to detect and acquire fluorescence signal data from biological microchips (biochips) is provided. The portable biochip scanner device employs a laser for emitting an excitation beam. An optical fiber delivers the laser beam to a portable biochip scanner. A lens collimates the laser beam, the collimated laser beam is deflected by a dichroic mirror and focused by an objective lens onto a biochip. The fluorescence light from the biochip is collected and collimated by the objective lens. The fluorescence light is delivered to a photomultiplier tube (PMT) via an emission filter and a focusing lens. The focusing lens focuses the fluorescence light into a pinhole. A signal output of the PMT is processed and displayed.

  10. Chalcogenide molded freeform optics for mid-infrared lasers

    NASA Astrophysics Data System (ADS)

    Chenard, Francois; Alvarez, Oseas; Yi, Allen

    2017-05-01

    High-precision chalcogenide molded micro-lenses were produced to collimate mid-infrared Quantum Cascade Lasers (QCLs). Molded cylindrical micro-lens prototypes with aspheric contour (acylindrical), high numerical aperture (NA 0.8) and small focal length (f<2 mm) were fabricated to collimate the QCL fast-axis beam. Another innovative freeform micro-lens has an input acylindrical surface to collimate the fast axis and an orthogonal output acylindrical surface to collimate the slow axis. The thickness of the freeform lens is such that the output fast- and slow-axis beams are circular. This paper presents results on the chalcogenide molded freeform micro-lens designed to collimate and circularize QCL at 4.6 microns.

  11. In vacuum diamond sensor scanner for beam halo measurements in the beam line at the KEK Accelerator Test Facility

    NASA Astrophysics Data System (ADS)

    Liu, S.; Bogard, F.; Cornebise, P.; Faus-Golfe, A.; Fuster-Martínez, N.; Griesmayer, E.; Guler, H.; Kubytskyi, V.; Sylvia, C.; Tauchi, T.; Terunuma, N.; Bambade, P.

    2016-10-01

    The investigation of beam halo transverse distributions is important for the understanding of beam losses and the control of backgrounds in Future Linear Colliders (FLC). A novel in vacuum diamond sensor (DSv) scanner with four strips has been designed and developed for the investigation of the beam halo transverse distributions and also for the diagnostics of Compton recoil electrons after the interaction point (IP) of ATF2, a low energy (1.3 GeV) prototype of the final focus system for the ILC and CLIC linear collider projects. Using the DSv, a dynamic range of ∼106 has been successfully demonstrated and confirmed for the first time in simultaneous beam core (∼109 electrons) and beam halo (∼103 electrons) measurements at ATF2. This report presents the characterization, performance studies and tests of diamond sensors using an α source, as well as using the electron beams at PHIL, a low energy < 5 MeV photo-injector at LAL, and at ATF2. First beam halo measurement results using the DSv at ATF2 with different beam intensities and vacuum levels are also presented. Such measurements not only allow one to evaluate the different sources of beam halo generation but also to define the requirements for a suitable collimation system to be installed at ATF2, as well as to optimize its performance during future operation.

  12. Real-time proton beam range monitoring by means of prompt-gamma detection with a collimated camera

    NASA Astrophysics Data System (ADS)

    Roellinghoff, F.; Benilov, A.; Dauvergne, D.; Dedes, G.; Freud, N.; Janssens, G.; Krimmer, J.; Létang, J. M.; Pinto, M.; Prieels, D.; Ray, C.; Smeets, J.; Stichelbaut, F.; Testa, E.

    2014-03-01

    Prompt-gamma profile was measured at WPE-Essen using 160 MeV protons impinging a movable PMMA target. A single collimated detector was used with time-of-flight (TOF) to reduce the background due to neutrons. The target entrance rise and the Bragg peak falloff retrieval precision was determined as a function of incident proton number by a fitting procedure using independent data sets. Assuming improved sensitivity of this camera design by using a greater number of detectors, retrieval precisions of 1 to 2 mm (rms) are expected for a clinical pencil beam. TOF improves the contrast-to-noise ratio and the performance of the method significantly.

  13. Objective Lens Optimized for Wavefront Delivery, Pupil Imaging, and Pupil Ghosting

    NASA Technical Reports Server (NTRS)

    Olzcak, Gene

    2009-01-01

    An interferometer objective lens (or diverger) may be used to transform a collimated beam into a diverging or converging beam. This innovation provides an objective lens that has diffraction-limited optical performance that is optimized at two sets of conjugates: imaging to the objective focus and imaging to the pupil. The lens thus provides for simultaneous delivery of a high-quality beam and excellent pupil resolution properties.

  14. Differential correction system of laser beam directional dithering based on symmetrical beamsplitter

    NASA Astrophysics Data System (ADS)

    Hongwei, Yang; Wei, Tao; Xiaoqia, Yin; Hui, Zhao

    2018-02-01

    This paper proposes a differential correction system with a differential optical path and a symmetrical beamsplitter for correcting the directional dithering of the laser beams. This system can split a collimated laser beam into two laser beams with equal and opposite movements. Thus, the positional averages of the two split laser beams remain constant irrespective of the dithering angle. The symmetrical beamsplitter designed based on transfer matrix principle is to balance the optical paths and irradiances of the two laser beams. Experimental results show that the directional dithering is reduced to less than one-pixel value. Finally, two examples show that this system can be widely used in one-dimensional measurement.

  15. The design, physical properties and clinical utility of an iris collimator for robotic radiosurgery

    NASA Astrophysics Data System (ADS)

    Echner, G. G.; Kilby, W.; Lee, M.; Earnst, E.; Sayeh, S.; Schlaefer, A.; Rhein, B.; Dooley, J. R.; Lang, C.; Blanck, O.; Lessard, E.; Maurer, C. R., Jr.; Schlegel, W.

    2009-09-01

    Robotic radiosurgery using more than one circular collimator can improve treatment plan quality and reduce total monitor units (MU). The rationale for an iris collimator that allows the field size to be varied during treatment delivery is to enable the benefits of multiple-field-size treatments to be realized with no increase in treatment time due to collimator exchange or multiple traversals of the robotic manipulator by allowing each beam to be delivered with any desired field size during a single traversal. This paper describes the Iris™ variable aperture collimator (Accuray Incorporated, Sunnyvale, CA, USA), which incorporates 12 tungsten-copper alloy segments in two banks of six. The banks are rotated by 30° with respect to each other, which limits the radiation leakage between the collimator segments and produces a 12-sided polygonal treatment beam. The beam is approximately circular, with a root-mean-square (rms) deviation in the 50% dose radius of <0.8% (corresponding to <0.25 mm at the 60 mm field size) and an rms variation in the 20-80% penumbra width of about 0.1 mm at the 5 mm field size increasing to about 0.5 mm at 60 mm. The maximum measured collimator leakage dose rate was 0.07%. A commissioning method is described by which the average dose profile can be obtained from four profile measurements at each depth based on the periodicity of the isodose line variations with azimuthal angle. The penumbra of averaged profiles increased with field size and was typically 0.2-0.6 mm larger than that of an equivalent fixed circular collimator. The aperture reproducibility is <=0.1 mm at the lower bank, diverging to <=0.2 mm at a nominal treatment distance of 800 mm from the beam focus. Output factors (OFs) and tissue-phantom-ratio data are identical to those used for fixed collimators, except the OFs for the two smallest field sizes (5 and 7.5 mm) are considerably lower for the Iris Collimator. If average collimator profiles are used, the assumption of circular symmetry results in dose calculation errors that are <1 mm or <1% for single beams across the full range of field sizes; errors for multiple non-coplanar beam treatment plans are expected to be smaller. Treatment plans were generated for 19 cases using the Iris Collimator (12 field sizes) and also using one and three fixed collimators. The results of the treatment planning study demonstrate that the use of multiple field sizes achieves multiple plan quality improvements, including reduction of total MU, increase of target volume coverage and improvements in conformality and homogeneity compared with using a single field size for a large proportion of the cases studied. The Iris Collimator offers the potential to greatly increase the clinical application of multiple field sizes for robotic radiosurgery.

  16. Holographic Optics for Missile Guidance Systems.

    DTIC Science & Technology

    1978-12-20

    according to SnelPs Law when the ray encounters a change in index of refraction (i.e., a change in the speed of light ). Conventional lenses and prisms are...AA ’ to change the magnification of the system , or individual light sources may be used to address each lens group . Each lens group consists of four...individual lens elements. Element I collimates the light from a source H, 17—mm away . Element II uses the collimated light beam , 8 —. now propagat

  17. [Characterization of a diode system for in vivo dosimetry with electron beams].

    PubMed

    Ragona, R; Rossetti, V; Lucio, F; Anglesio, S; Giglioli, F R

    2001-10-01

    Current quality assurance regulation stresses the basic role of in vivo dosimetry. Our study evaluates the usefulness and reliability of semiconductor diodes in determining the electron absorbed dose. P-type EDE semiconductor detectors were irradiated with electron beams of different energies produced by a CGR Saturn Therac 20. The diode and ionization chamber response were compared, and effect of energy value, collimator opening, source skin distance and gantry angle on diode response was studied. Measurements show a maximum increment of about 20% in diode response increasing the beam energy (6-20 MeV). The response also increases with: collimator opening, reaching 5% with field sizes larger than 10x10 cm2 (with the exception of 20 MeV energy); SSD increase (with a maximum of 8% for 20 MeV); transversal gantry incidence, compared with the diode longitudinal axis; it does not affect the response in the interval of +/- 45 degrees. Absorbed dose attenuation at dmax, due to the presence of diode on the axis of the beam as a function of electron energy was also determined : the maximum attenuation value is 15% in 6 MeV electron beams. A dose calculation algorithm, taking into account diode response dependence was outlined. In vivo dosimetry was performed in 92 fields for 80 patients, with an agreement of +/-4 % (1 SD) between prescribed and measured dose. It is possible to use the EDE semiconductor detectors on a quality control program of dose delivery for electron beam therapy, but particular attention should be paid to the beam incidence angle and diode dose attenuation.

  18. Neutron range spectrometer

    DOEpatents

    Manglos, S.H.

    1988-03-10

    A neutron range spectrometer and method for determining the neutron energy spectrum of a neutron emitting source are disclosed. Neutrons from the source are colliminated along a collimation axis and a position sensitive neutron counter is disposed in the path of the collimated neutron beam. The counter determines positions along the collimation axis of interactions between the neutrons in the neutron beam and a neutron-absorbing material in the counter. From the interaction positions, a computer analyzes the data and determines the neutron energy spectrum of the neutron beam. The counter is preferably shielded and a suitable neutron-absorbing material is He-3. 1 fig.

  19. Remanent dose rates around the collimators of the LHC beam cleaning insertions.

    PubMed

    Brugger, M; Roesler, S

    2005-01-01

    The LHC will require an extremely powerful and unprecedented collimation system. As approximately 30% of the LHC beam is lost in the cleaning insertions, these will become some of the most radioactive locations around the entire LHC ring. Thus, remanent dose rates to be expected during later repair or maintenance interventions must be considered in the design phase itself. As a consequence, the beam cleaning insertions form a unique test bed for a recently developed approach to calculate remanent dose rates. A set of simulations, different in complexity, is used in order to evaluate methods for the estimation of remanent dose rates. The scope, as well as the restrictions, of the omega-factor method are shown and compared with the explicit simulation approach. The latter is then used to calculate remanent dose rates in the beam cleaning insertions. Furthermore, a detailed example for maintenance dose planning is given.

  20. Collimator design for a multipinhole brain SPECT insert for MRI

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Van Audenhaege, Karen; Van Holen, Roel; Vanhove, Christian

    Purpose: Brain single photon emission computed tomography (SPECT) imaging is an important clinical tool, with unique tracers for studying neurological diseases. Nowadays, most commercial SPECT systems are combined with x-ray computed tomography (CT) in so-called SPECT/CT systems to obtain an anatomical background for the functional information. However, while CT images have a high spatial resolution, they have a low soft-tissue contrast, which is an important disadvantage for brain imaging. Magnetic resonance imaging (MRI), on the other hand, has a very high soft-tissue contrast and does not involve extra ionizing radiation. Therefore, the authors designed a brain SPECT insert that canmore » operate inside a clinical MRI. Methods: The authors designed and simulated a compact stationary multipinhole SPECT insert based on digital silicon photomultiplier detector modules, which have shown to be MR-compatible and have an excellent intrinsic resolution (0.5 mm) when combined with a monolithic 2 mm thick LYSO crystal. First, the authors optimized the different parameters of the SPECT system to maximize sensitivity for a given target resolution of 7.2 mm in the center of the field-of-view, given the spatial constraints of the MR system. Second, the authors performed noiseless simulations of two multipinhole configurations to evaluate sampling and reconstructed resolution. Finally, the authors performed Monte Carlo simulations and compared the SPECT insert with a clinical system with ultrahigh-resolution (UHR) fan beam collimators, based on contrast-to-noise ratio and a visual comparison of a Hoffman phantom with a 9 mm cold lesion. Results: The optimization resulted in a stationary multipinhole system with a collimator radius of 150.2 mm and a detector radius of 172.67 mm, which corresponds to four rings of 34 diSPM detector modules. This allows the authors to include eight rings of 24 pinholes, which results in a system volume sensitivity of 395 cps/MBq. Noiseless simulations show sufficient axial sampling (in a Defrise phantom) and a reconstructed resolution of 5.0 mm (in a cold-rod phantom). The authors compared the 24-pinhole setup with a 34-pinhole system (with the same detector radius but a collimator radius of 156.63 mm) and found that 34 pinholes result in better uniformity but a worse reconstruction of the cold-rod phantom. The authors also compared the 24-pinhole system with a clinical triple-head UHR fan beam system based on contrast-to-noise ratio and found that the 24-pinhole setup performs better for the 6 mm hot and the 16 mm cold lesions and worse for the 8 and 10 mm hot lesions. Finally, the authors reconstructed noisy projection data of a Hoffman phantom with a 9 mm cold lesion and found that the lesion was slightly better visible on the multipinhole image compared to the fan beam image. Conclusions: The authors have optimized a stationary multipinhole SPECT insert for MRI and showed the feasibility of doing brain SPECT imaging inside a MRI with an image quality similar to the best clinical SPECT systems available.« less

  1. 3-dimensional beam scanning system for particle radiation therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leemann, C.; Alonso, J.; Grunder, H.

    1977-03-01

    In radiation therapy treatment volumes up to several liters have to be irradiated. Today's charged particle programs use ridge filters, scattering foils, occluding rings collimators and boluses to shape the dose distribution. An alternative approach, scanning of a small diameter beam, is analyzed and tentative systems specifications are derived. Critical components are scheduled for fabrication and testing at LBL.

  2. Development of a low-energy x-ray camera for the imaging of secondary electron bremsstrahlung x-ray emitted during proton irradiation for range estimation.

    PubMed

    Ando, Koki; Yamaguchi, Mitsutaka; Yamamoto, Seiichi; Toshito, Toshiyuki; Kawachi, Naoki

    2017-06-21

    Imaging of secondary electron bremsstrahlung x-ray emitted during proton irradiation is a possible method for measurement of the proton beam distribution in phantom. However, it is not clear that the method is used for range estimation of protons. For this purpose, we developed a low-energy x-ray camera and conducted imaging of the bremsstrahlung x-ray produced during irradiation of proton beams. We used a 20 mm  ×  20 mm  ×  1 mm finely grooved GAGG scintillator that was optically coupled to a one-inch square high quantum efficiency (HQE)-type position-sensitive photomultiplier tube to form an imaging detector. The imaging detector was encased in a 2 cm-thick tungsten container, and a pinhole collimator was attached to its camera head. After performance of the camera was evaluated, secondary electron bremsstrahlung x-ray imaging was conducted during irradiation of the proton beams for three different proton energies, and the results were compared with Monte Carlo simulation as well as calculated value. The system spatial resolution and sensitivity of the developed x-ray camera with 1.5 mm-diameter pinhole collimator were estimated to be 32 mm FWHM and 5.2  ×  10 -7 for ~35 keV x-ray photons at 100 cm from the collimator surface, respectively. We could image the proton beam tracks by measuring the secondary electron bremsstrahlung x-ray during irradiation of the proton beams, and the ranges for different proton energies could be estimated from the images. The measured ranges from the images were well matched with the Monte Carlo simulation, and slightly smaller than the calculated values. We confirmed that the imaging of the secondary electron bremsstrahlung x-ray emitted during proton irradiation with the developed x-ray camera has the potential to be a new tool for proton range estimations.

  3. Incorporation of fiber optic beam shaping into a laparoscopic probe for laser stimulation of the cavernous nerves

    NASA Astrophysics Data System (ADS)

    Tozburun, Serhat; Lagoda, Gwen A.; Mayeh, Mona; Burnett, Arthur L.; Farahi, Faramarz; Fried, Nathaniel M.

    2010-02-01

    The cavernous nerves (CN) course along the prostate surface and are responsible for erectile function. Improved identification and preservation of the CN's is critical to maintaining sexual potency after prostate cancer surgery. Noncontact optical nerve stimulation (ONS) of the CN's was recently demonstrated in a rat model, in vivo, as a potential alternative to electrical nerve stimulation (ENS) for identification of the CN's during prostate surgery. However, the therapeutic window for ONS is narrow, so optimal design of the fiber optic delivery system is critical for safe, reproducible stimulation. This study describes modeling, assembly, and testing of an ONS probe for delivering a small, collimated, flat-top laser beam for uniform CN stimulation. A direct comparison of the magnitude and response time of the intracavernosal pressure (ICP) for both Gaussian and flat-top spatial beam profiles was performed. Thulium fiber laser radiation (λ=1870 nm) was delivered through a 200-μm fiber, with distal fiber tip chemically etched to convert a Gaussian to flat-top beam profile. The laser beam was collimated to a 1-mm-diameter spot using an aspheric lens. Computer simulations of light propagation were used to optimize the probe design. The 10-Fr (3.4-mm-OD) laparoscopic probe provided a constant radiant exposure at the nerve surface. The probe was tested in four rats, in vivo. ONS of the CN's was performed with a 1-mm-diameter spot, 5- ms pulse duration, and pulse rate of 20 Hz for a duration of 15-30 s. The flat-top laser beam profile consistently produced a faster and higher ICP response at a lower radiant exposure than the Gaussian beam profile due, in part, to easier alignment of the more uniform beam with nerve. With further development, ONS may be used as a diagnostic tool for identification of the CN's during laparoscopic and robotic nerve-sparing prostate cancer surgery.

  4. Effect of leaded glasses and thyroid shielding on cone beam CT radiation dose in an adult female phantom

    PubMed Central

    Goren, AD; Prins, RD; Dauer, LT; Quinn, B; Al-Najjar, A; Faber, RD; Patchell, G; Branets, I; Colosi, DC

    2013-01-01

    Objectives: This study aims to demonstrate the effectiveness of leaded glasses in reducing the lens of eye dose and of lead thyroid collars in reducing the dose to the thyroid gland of an adult female from dental cone beam CT (CBCT). The effect of collimation on the radiation dose in head organs is also examined. Methods: Dose measurements were conducted by placing optically stimulated luminescent dosemeters in an anthropomorphic female phantom. Eye lens dose was measured by placing a dosemeter on the anterior surface of the phantom eye location. All exposures were performed on one commercially available dental CBCT machine, using selected collimation and exposure techniques. Each scan technique was performed without any lead shielding and then repeated with lead shielding in place. To calculate the percent reduction from lead shielding, the dose measured with lead shielding was divided by the dose measured without lead shielding. The percent reduction from collimation was calculated by comparing the dose measured with collimation to the dose measured without collimation. Results: The dose to the internal eye for one of the scans without leaded glasses or thyroid shield was 0.450 cGy and with glasses and thyroid shield was 0.116 cGy (a 74% reduction). The reduction to the lens of the eye was from 0.396 cGy to 0.153 cGy (a 61% reduction). Without glasses or thyroid shield, the thyroid dose was 0.158 cGy; and when both glasses and shield were used, the thyroid dose was reduced to 0.091 cGy (a 42% reduction). Conclusions: Collimation alone reduced the dose to the brain by up to 91%, with a similar reduction in other organs. Based on these data, leaded glasses, thyroid collars and collimation minimize the dose to organs outside the field of view. PMID:23412460

  5. Nondestructive Evaluation of Aircraft Composites Using Terahertz Time Domain Spectroscopy

    DTIC Science & Technology

    2008-12-10

    substrate lenses : collimating and aplanatic. In a collimating lens , the rays emitted near the optic axis emerge as a collimated beam, while the rays...emitted at larger angles emerge at substantial angles or are internally reflected and lost. The aplanatic hyperhemispherical lens design, which...propagates out of the lens before it spreads. Many of the hemispherical designs result in the spreading of the THz beam at a given angle , which can then be

  6. Patient handling system for carbon ion beam scanning therapy

    PubMed Central

    Shirai, Toshiyuki; Takei, Yuka; Furukawa, Takuji; Inaniwa, Taku; Matsuzaki, Yuka; Kumagai, Motoki; Murakami, Takeshi; Noda, Koji

    2012-01-01

    Our institution established a new treatment facility for carbon ion beam scanning therapy in 2010. The major advantages of scanning beam treatment compared to the passive beam treatment are the following: high dose conformation with less excessive dose to the normal tissues, no bolus compensator and patient collimator/ multi‐leaf collimator, better dose efficiency by reducing the number of scatters. The new facility was designed to solve several problems encountered in the existing facility, at which several thousand patients were treated over more than 15 years. Here, we introduce the patient handling system in the new treatment facility. The new facility incorporates three main systems, a scanning irradiation system (S‐IR), treatment planning system (TPS), and patient handling system (PTH). The PTH covers a wide range of functions including imaging, geometrical/position accuracy including motion management (immobilization, robotic arm treatment bed), layout of the treatment room, treatment workflow, software, and others. The first clinical trials without respiratory gating have been successfully started. The PTH allows a reduction in patient stay in the treatment room to as few as 7 min. The PTH plays an important role in carbon ion beam scanning therapy at the new institution, particularly in the management of patient handling, application of image‐guided therapy, and improvement of treatment workflow, and thereby allows substantially better treatment at minimum cost. PACS numbers: 87.56.‐v; 87.57.‐s; 87.55.‐x PMID:23149784

  7. Evaluation of myocardial defect detection between parallel-hole and fan-beam SPECT using the Hotelling trace

    NASA Astrophysics Data System (ADS)

    Wollenweber, S. D.; Tsui, B. M. W.; Lalush, D. S.; Frey, E. C.; Gullberg, G. T.

    1998-08-01

    The objective of this study was to implement the Hotelling trace (HT) to evaluate the potential increase in defect detection in myocardial SPECT using high-resolution fan-beam (HRF) versus parallel-hole (HRP) collimation and compare results to a previously reported human observer study (G.K. Gregoriou et al., ibid., vol. 42, p. 1267-75, 1995). Projection data from the 3D MCAT torso phantom were simulated including the effects of attenuation, collimator-detector response blurring and scatter. Poisson noise fluctuations were then simulated. The HRP and HRF collimators had the same spatial resolution at 20 cm. The total counts in the projection data sets were proportional to the detection efficiencies of the collimators and on the order of that found in clinical Tc-99m studies. In six left-ventricular defect locations, the HT found for HRF was superior to that for HRP collimation. For HRF collimation, the HT was calculated for reconstructed images using 64/spl times/64, 128/spl times/128 and 192/spl times/192 grid sizes. The results demonstrate substantial improvement in myocardial defect detection when the grid size was increased from 64/spl times/64 to 128/spl times/128 and slight improvement from 128/spl times/128 to 192/spl times/192. Also, the performance of the Hotelling observer in terms of the HT at the different grid sizes correlates at better than 0.95 to that found in human observers in a previously reported observer experiment and ROC study.

  8. Field precision machining technology of target chamber in ICF lasers

    NASA Astrophysics Data System (ADS)

    Xu, Yuanli; Wu, Wenkai; Shi, Sucun; Duan, Lin; Chen, Gang; Wang, Baoxu; Song, Yugang; Liu, Huilin; Zhu, Mingzhi

    2016-10-01

    In ICF lasers, many independent laser beams are required to be positioned on target with a very high degree of accuracy during a shot. The target chamber provides a precision platform and datum reference for final optics assembly and target collimation and location system. The target chamber consists of shell with welded flanges, reinforced concrete pedestal, and lateral support structure. The field precision machining technology of target chamber in ICF lasers have been developed based on ShenGuangIII (SGIII). The same center of the target chamber is adopted in the process of design, fabrication, and alignment. The technologies of beam collimation and datum reference transformation are developed for the fabrication, positioning and adjustment of target chamber. A supporting and rotating mechanism and a special drilling machine are developed to bore the holes of ports. An adjustment mechanism is designed to accurately position the target chamber. In order to ensure the collimation requirements of the beam leading and focusing and the target positioning, custom-machined spacers are used to accurately correct the alignment error of the ports. Finally, this paper describes the chamber center, orientation, and centering alignment error measurements of SGIII. The measurements show the field precision machining of SGIII target chamber meet its design requirement. These information can be used on similar systems.

  9. The value of thyroid shielding in intraoral radiography

    PubMed Central

    Hazenoot, Bart; Sanderink, Gerard C H; Berkhout, W Erwin R

    2016-01-01

    Objectives: To evaluate the utility of the application of a thyroid shield in intraoral radiography when using rectangular collimation. Methods: Experimental data were obtained by measuring the absorbed dose at the position of the thyroid gland in a RANDO® (The Phantom Laboratory, Salem, NY) male phantom with a dosemeter. Four protocols were tested: round collimation and rectangular collimation, both with and without thyroid shield. Five exposure positions were deployed: upper incisor (Isup), upper canine (Csup), upper premolar (Psup), upper molar (Msup) and posterior bitewing (BW). Exposures were made with 70 kV and 7 mA and were repeated 10 times. The exposure times were as recommended for the exposure positions for the respective collimator type by the manufacturer for digital imaging. The data were statistically analyzed with a three-way ANOVA test. Significance was set at p < 0.01. Results: The ANOVA test revealed that the differences between mean doses of all protocols and geometries were statistically significant, p < 0.001. For the Isup, thyroid dose levels were comparable with both collimators at a level indicating primary beam exposure. Thyroid shield reduced this dose with circa 75%. For the Csup position, round collimation also revealed primary beam exposure, and thyroid shield yield was 70%. In Csup with rectangular collimation, the thyroid dose was reduced with a factor 4 compared with round collimation and thyroid shield yielded an additional 42% dose reduction. The thyroid dose levels for the Csup, Psup, Msup and BW exposures were lower with rectangular collimation without thyroid shield than with round collimation with thyroid shield. With rectangular collimation, the thyroid shield in Psup, Msup and BW reduced the dose 10% or less, where dose levels were already low, implying no clinical significance. Conclusions: For the exposures in the upper anterior region, thyroid shield results in an important dose reduction for the thyroid. For the other exposures, thyroid shield augments little to the reduction achieved by rectangular collimation. The use of thyroid shield is to be advised, when performing upper anterior radiography. PMID:27008105

  10. Large deflection angle, high-power adaptive fiber optics collimator with preserved near-diffraction-limited beam quality.

    PubMed

    Zhi, Dong; Ma, Yanxing; Chen, Zilun; Wang, Xiaolin; Zhou, Pu; Si, Lei

    2016-05-15

    We report on the development of a monolithic adaptive fiber optics collimator, with a large deflection angle and preserved near-diffraction-limited beam quality, that has been tested at a maximal output power at the 300 W level. Additionally, a new measurement method of beam quality (M2 factor) is developed. Experimental results show that the deflection angle of the collimated beam is in the range of 0-0.27 mrad in the X direction and 0-0.19 mrad in the Y direction. The effective working frequency of the device is about 710 Hz. By employing the new measurement method of the M2 factor, we calculate that the beam quality is Mx2=1.35 and My2=1.24, which is in agreement with the result from the beam propagation analyzer and is preserved well with the increasing output power.

  11. Large beam deflection using cascaded prism array

    NASA Astrophysics Data System (ADS)

    Wang, Wei-Chih; Tsui, Chi-Leung

    2012-04-01

    Endoscopes have been utilize in the medical field to observe the internals of the human body to assist the diagnosis of diseases, such as breathing disorders, internal bleeding, stomach ulcers, and urinary tract infections. Endoscopy is also utilized in the procedure of biopsy for the diagnosis of cancer. Conventional endoscopes suffer from the compromise between overall size and image quality due to the required size of the sensor for acceptable image quality. To overcome the size constraint while maintaining the capture image quality, we propose an electro-optic beam steering device based on thermal-plastic polymer, which has a small foot-print (~5mmx5mm), and can be easily fabricated using conventional hot-embossing and micro-fabrication techniques. The proposed device can be implemented as an imaging device inside endoscopes to allow reduction in the overall system size. In our previous work, a single prism design has been used to amplify the deflection generated by the index change of the thermal-plastic polymer when a voltage is applied; it yields a result of 5.6° deflection. To further amplify the deflection, a new design utilizing a cascading three-prism array has been implemented and a deflection angle to 29.2° is observed. The new design amplifies the beam deflection, while keeping the advantage of simple fabrication made possible by thermal-plastic polymer. Also, a photo-resist based collimator lens array has been added to reduce and provide collimation of the beam for high quality imaging purposes. The collimator is able to collimate the exiting beam at 4 μm diameter for up to 25mm, which potentially allows high resolution image capturing.

  12. Reaching record-low β* at the CERN Large Hadron Collider using a novel scheme of collimator settings and optics

    NASA Astrophysics Data System (ADS)

    Bruce, R.; Bracco, C.; De Maria, R.; Giovannozzi, M.; Mereghetti, A.; Mirarchi, D.; Redaelli, S.; Quaranta, E.; Salvachua, B.

    2017-03-01

    The Large Hadron Collider (LHC) at CERN is built to collide intense proton beams with an unprecedented energy of 7 TeV. The design stored energy per beam of 362 MJ makes the LHC beams highly destructive, so that any beam losses risk to cause quenches of superconducting magnets or damage to accelerator components. Collimators are installed to protect the machine and they define a minimum normalized aperture, below which no other element is allowed. This imposes a limit on the achievable luminosity, since when squeezing β* (the β-function at the collision point) to smaller values for increased luminosity, the β-function in the final focusing system increases. This leads to a smaller normalized aperture that risks to go below the allowed collimation aperture. In the first run of the LHC, this was the main limitation on β*, which was constrained to values above the design specification. In this article, we show through theoretical and experimental studies how tighter collimator openings and a new optics with specific phase-advance constraints allows a β* as small as 40 cm, a factor 2 smaller than β*=80 cm used in 2015 and significantly below the design value β*=55 cm, in spite of a lower beam energy. The proposed configuration with β*=40 cm has been successfully put into operation and has been used throughout 2016 as the LHC baseline. The decrease in β* compared to 2015 has been an essential contribution to reaching and surpassing, in 2016, the LHC design luminosity for the first time, and to accumulating a record-high integrated luminosity of around 40 fb-1 in one year, in spite of using less bunches than in the design.

  13. First Results from a Microfocus X-Ray System for Macromolecular Crystallography

    NASA Technical Reports Server (NTRS)

    Gubarev, Mikhail; Ciszak, Ewa; Ponomarev, Igor; Gibson, Walter; Joy, Marshall

    1999-01-01

    The design and performance of a 40 Watt laboratory crystallography system optimized for the structure determination of small protein crystals are described. This system combines a microfocus x-ray generator (40 microns FWHM spot size at a power level of 40 Watts) and a short focal length (F = 2.6 mm) polycapillary collimating optic, and produces a small diameter quasi-parallel x-ray beam. Measurements of x-ray flux, divergence and spectral purity of the resulting x-ray beam are presented. The x-ray flux in a 250 microns diameter aperture produced by the microfocus system is 14.7 times higher .than that from a 3.15 kW rotating anode generator equipped with graphite monochromator. Crystallography data taken with the microfocus system are presented, and indicate that the divergence and spectral purity of the x-ray are sufficient to refine the diffraction data using a standard crystallographic software. Significant additional improvements in flux and beam divergence are possible, and plans for achieving these coals are discussed.

  14. Study and realization of an obstacle detection infrared system for automotive use

    NASA Astrophysics Data System (ADS)

    Alaouiamine, Mohammed

    1991-08-01

    The main technological options available in the field of obstacle detection are presented. Ultrasound, microwave, and infrared detection systems are reviewed. The reasons for choosing an infrared solution are outlined. The problems involved in developing an obstacle detection system in the near infrared are discussed. Weather condition effects, interference limitations due to multiple onboard sensors, and range detection influence are some of the problems studied. A collimated, mechanically scanned, and pulsed infrared beam is proposed to overcome some of these problems. Performances of a first and second prototype made using this system are presented.

  15. Real-time optical multiple object recognition and tracking system and method

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin (Inventor); Liu, Hua-Kuang (Inventor)

    1990-01-01

    System for optically recognizing and tracking a plurality of objects within a field of vision. Laser (46) produces a coherent beam (48). Beam splitter (24) splits the beam into object (26) and reference (28) beams. Beam expanders (50) and collimators (52) transform the beams (26, 28) into coherent collimated light beams (26', 28'). A two-dimensional SLM (54), disposed in the object beam (26'), modulates the object beam with optical information as a function of signals from a first camera (16) which develops X and Y signals reflecting the contents of its field of vision. A hololens (38), positioned in the object beam (26') subsequent to the modulator (54), focuses the object beam at a plurality of focal points (42). A planar transparency-forming film (32), disposed with the focal points on an exposable surface, forms a multiple position interference filter (62) upon exposure of the surface and development processing of the film (32). A reflector (53) directing the reference beam (28') onto the film (32), exposes the surface, with images focused by the hololens (38), to form interference patterns on the surface. There is apparatus (16', 64) for sensing and indicating light passage through respective ones of the positions of the filter (62), whereby recognition of objects corresponding to respective ones of the positions of the filter (62) is affected. For tracking, apparatus (64) focuses light passing through the filter (62) onto a matrix of CCD's in a second camera (16') to form a two-dimensional display of the recognized objects.

  16. TU-EF-304-11: Therapeutic Benefits of Collimation in Spot Scanning Proton Therapy in the Treatment of Brain Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moignier, A; Gelover, E; Wang, D

    Purpose: A dynamic collimation system (DCS) based on two orthogonal pairs of mobile trimmer blades has recently been proposed to reduce the lateral penumbra in spot scanning proton therapy (SSPT). The purpose of this work is to quantify the therapeutic benefit of using the DCS for SSPT of brain cancer by comparing un-collimated and collimated treatment plans. Methods: Un-collimated and collimated brain treatment plans were created for five patients, previously treated with SSPT, using an in-house treatment planning system capable of modeling collimated and un-collimated beamlets. Un-collimated plans reproduced the clinically delivered plans in terms of target coverage and organ-at-riskmore » (OAR) sparing, whereas collimated plans were re-optimized to improve the organ-at-risk sparing while maintaining target coverage. Physical and biological comparison metrics such as dose distribution conformity, mean and maximum doses, normal tissue complication probability (NTCP) and risk of secondary brain cancer were used to evaluate the plans. Results: The DCS systematically improved the dose distribution conformity while preserving the target coverage. The average reduction of the mean dose to the 10-mm ring surrounding the target and the healthy brain were 7.1% (95% CI: 4.2%–9.9%; p<0.01) and 14.3% (95% CI: 7.8%–20.8%; p<0.01), respectively. This yielded an average reduction of 12.0% (95% CI: 8.2%–15.7%; p<0.01) for the brain necrosis NTCP using the Flickinger model, and 14.2% (95% CI: 7.7%–20.8%; p<0.01) for the risk of secondary brain cancer. The average maximum dose reductions for the brainstem, chiasm, optic nerves, cochleae and pituitary gland when comparing un-collimated and collimated plans were 14.3%, 10.4%, 11.2%, 13.0%, 12.9% and 3.4%, respectively. Evaluating individual plans using the Lyman-Kutcher-Burman NTCP model also yielded improvements. Conclusion: The lateral penumbra reduction performed by the DCS increases the normal tissue sparing capabilities of SSPT for brain tumor treatment while preserving the target coverage. This research was financially supported by Ion Beam Applications S.A. (IBA, Louvain-La-Neuve, Belgium)« less

  17. Intensity-modulated radiation therapy (IMRT) with different combinations of treatment-planning systems and linacs: issues and how to detect them.

    PubMed

    Dobler, Barbara; Lorenz, Friedlieb; Wertz, Hansjörg; Polednik, Martin; Wolff, Dirk; Steil, Volker; Lohr, Frank; Wenz, Frederik

    2006-08-01

    To compare different combinations of intensity-modulated radiation therapy (IMRT) system components with regard to quality assurance (QA), especially robustness against malfunctions and dosimetry. Three different treatment-planning systems (TPS), two types of linacs and three multileaf collimator (MLC) types were compared: commissioning procedures were performed for the combination of the TPS Corvus 5.0 (Nomos) and KonRad v2.1.3 (Siemens OCS) with the linacs KD2 (Siemens) and Synergy (Elekta). For PrecisePLAN 2.03 (Elekta) measurements were performed for Elekta Synergy only. As record and verify (R&V) system Multi-Access v7 (IMPAC) was used. The use of the serial tomotherapy system Peacock (Nomos) was investigated in combination with the Siemens KD2 linac. In the comparison of calculated to measured dose, problems were encountered for the combination of KonRad and Elekta MLC as well as for the Peacock system. Multi-Access failed to assign the collimator angle correctly for plans with multiple collimator angles per beam. Communication problems of Multi-Access with both linacs were observed, resulting in incorrect recording of the treatment. All reported issues were addressed by the manufacturers. For the commissioning of IMRT systems, the whole chain from the TPS to the linac has to be investigated. Components that passed the commissioning in another clinical environment can have severe malfunctions when used in a new environment. Therefore, not only single components but the whole chain from planning to delivery has to be evaluated in commissioning and checked regularly for QA.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koren, S; Kindler, J; Reich, E

    Purpose: We propose the use of a HDR X-ray source collimator to apply a conformal, relatively small, radiation suitable for a single fraction with short delivery time. In addition, this technique can be applied using a radioactive source. Methods: We have built a stainless steel 1.5 mm thick applicator, to accommodate the needle applicator of the Intra-Beam X-ray source. Additional cavity is created in the applicator to allow the hosting/nesting/positioning of a LED diode. This LED is allowing a pre-irradiation beam marking on the tissue. The visible light emitted from the opening of the collimated applicator will delineate/verify the aperturemore » of the kV beam to be applied, as well as serve as distance indicator and will assist in the determination of dose to be delivered. For the evaluation of the collimated spatial dose distribution we have performed water tank measurements using (IBA Dosimetry) with a 0.4 cc ion chamber (IBA Dosimetry). We have scanned a two dimensional array with 1mm pitch in depth and 0.3 mm step size laterally. Additional verifications were conducted using Gaf-Chromic film for PDD measurements and Optical Stimulated Luminescence Dosimetry (OSLD, Landauer inc.) for absolute dosimetry. Results: The collimated applicator enables a conformal irradiated cross-section of about 3 mm square at the applicator surface was used in this study. A 180 seconds of 50 kVp delivery yielded 29 Gy, 20.6 Gy and 14.5 Gy at 5, 10 and 15 mm depths respectively. These results are in good agreement with the needle applicator depth dose curve published data. Conclusion: We have demonstrated the feasibility of focal HDR brachytherapy for conjunctival and ocular tumors, using the Intra-Beam needle applicator with in-house developed collimator. The delivery time was found to be several minutes- suitable for an intra-operative procedure and will allow dose fractionation deliveries.« less

  19. Improved design of proton source and low energy beam transport line for European Spallation Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neri, L., E-mail: neri@lns.infn.it; Celona, L.; Gammino, S.

    2014-02-15

    The design update of the European Spallation Source (ESS) accelerator is almost complete and the construction of the prototype of the microwave discharge ion source able to provide a proton beam current larger than 70 mA to the 3.6 MeV Radio Frequency Quadrupole (RFQ) started. The source named PS-ESS (Proton Source for ESS) was designed with a flexible magnetic system and an extraction system able to merge conservative solutions with significant advances. The ESS injector has taken advantage of recent theoretical updates and new plasma diagnostics tools developed at INFN-LNS (Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare). Themore » design strategy considers the PS-ESS and the low energy beam transport line as a whole, where the proton beam behaves like an almost neutralized non-thermalized plasma. Innovative solutions have been used as hereinafter described. Thermo-mechanical optimization has been performed to withstand the chopped beam and the misaligned focused beam over the RFQ input collimator; the results are reported here.« less

  20. Energy- and time-resolved detection of prompt gamma-rays for proton range verification.

    PubMed

    Verburg, Joost M; Riley, Kent; Bortfeld, Thomas; Seco, Joao

    2013-10-21

    In this work, we present experimental results of a novel prompt gamma-ray detector for proton beam range verification. The detection system features an actively shielded cerium-doped lanthanum(III) bromide scintillator, coupled to a digital data acquisition system. The acquisition was synchronized to the cyclotron radio frequency to separate the prompt gamma-ray signals from the later-arriving neutron-induced background. We designed the detector to provide a high energy resolution and an effective reduction of background events, enabling discrete proton-induced prompt gamma lines to be resolved. Measuring discrete prompt gamma lines has several benefits for range verification. As the discrete energies correspond to specific nuclear transitions, the magnitudes of the different gamma lines have unique correlations with the proton energy and can be directly related to nuclear reaction cross sections. The quantification of discrete gamma lines also enables elemental analysis of tissue in the beam path, providing a better prediction of prompt gamma-ray yields. We present the results of experiments in which a water phantom was irradiated with proton pencil-beams in a clinical proton therapy gantry. A slit collimator was used to collimate the prompt gamma-rays, and measurements were performed at 27 positions along the path of proton beams with ranges of 9, 16 and 23 g cm(-2) in water. The magnitudes of discrete gamma lines at 4.44, 5.2 and 6.13 MeV were quantified. The prompt gamma lines were found to be clearly resolved in dimensions of energy and time, and had a reproducible correlation with the proton depth-dose curve. We conclude that the measurement of discrete prompt gamma-rays for in vivo range verification of clinical proton beams is feasible, and plan to further study methods and detector designs for clinical use.

  1. Sub-micrometre accurate free-form optics by three-dimensional printing on single-mode fibres

    PubMed Central

    Gissibl, Timo; Thiele, Simon; Herkommer, Alois; Giessen, Harald

    2016-01-01

    Micro-optics are widely used in numerous applications, such as beam shaping, collimation, focusing and imaging. We use femtosecond 3D printing to manufacture free-form micro-optical elements. Our method gives sub-micrometre accuracy so that direct manufacturing even on single-mode fibres is possible. We demonstrate the potential of our method by writing different collimation optics, toric lenses, free-form surfaces with polynomials of up to 10th order for intensity beam shaping, as well as chiral photonic crystals for circular polarization filtering, all aligned onto the core of the single-mode fibres. We determine the accuracy of our optics by analysing the output patterns as well as interferometrically characterizing the surfaces. We find excellent agreement with numerical calculations. 3D printing of microoptics can achieve sufficient performance that will allow for rapid prototyping and production of beam-shaping and imaging devices. PMID:27339700

  2. Sub-micrometre accurate free-form optics by three-dimensional printing on single-mode fibres.

    PubMed

    Gissibl, Timo; Thiele, Simon; Herkommer, Alois; Giessen, Harald

    2016-06-24

    Micro-optics are widely used in numerous applications, such as beam shaping, collimation, focusing and imaging. We use femtosecond 3D printing to manufacture free-form micro-optical elements. Our method gives sub-micrometre accuracy so that direct manufacturing even on single-mode fibres is possible. We demonstrate the potential of our method by writing different collimation optics, toric lenses, free-form surfaces with polynomials of up to 10th order for intensity beam shaping, as well as chiral photonic crystals for circular polarization filtering, all aligned onto the core of the single-mode fibres. We determine the accuracy of our optics by analysing the output patterns as well as interferometrically characterizing the surfaces. We find excellent agreement with numerical calculations. 3D printing of microoptics can achieve sufficient performance that will allow for rapid prototyping and production of beam-shaping and imaging devices.

  3. Sub-micrometre accurate free-form optics by three-dimensional printing on single-mode fibres

    NASA Astrophysics Data System (ADS)

    Gissibl, Timo; Thiele, Simon; Herkommer, Alois; Giessen, Harald

    2016-06-01

    Micro-optics are widely used in numerous applications, such as beam shaping, collimation, focusing and imaging. We use femtosecond 3D printing to manufacture free-form micro-optical elements. Our method gives sub-micrometre accuracy so that direct manufacturing even on single-mode fibres is possible. We demonstrate the potential of our method by writing different collimation optics, toric lenses, free-form surfaces with polynomials of up to 10th order for intensity beam shaping, as well as chiral photonic crystals for circular polarization filtering, all aligned onto the core of the single-mode fibres. We determine the accuracy of our optics by analysing the output patterns as well as interferometrically characterizing the surfaces. We find excellent agreement with numerical calculations. 3D printing of microoptics can achieve sufficient performance that will allow for rapid prototyping and production of beam-shaping and imaging devices.

  4. Contrast enhancement of transparencies

    NASA Technical Reports Server (NTRS)

    Shulman, A. R.; Lee, S. H.

    1976-01-01

    System can enhance or reduce contrast of photographic transparency for printing or projection by using constructive and destructive interference of collimated laser beam. System is potentially less expensive than electronic CRT methods and is more accurate than trial-and-error manual techniques.

  5. Applications of electron lenses: scraping of high-power beams, beam-beam compensation, and nonlinear optics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stancari, Giulio

    Electron lenses are pulsed, magnetically confined electron beams whose current-density profile is shaped to obtain the desired effect on the circulating beam. Electron lenses were used in the Fermilab Tevatron collider for bunch-by-bunch compensation of long-range beam-beam tune shifts, for removal of uncaptured particles in the abort gap, for preliminary experiments on head-on beam-beam compensation, and for the demonstration of halo scraping with hollow electron beams. Electron lenses for beam-beam compensation are being commissioned in the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory (BNL). Hollow electron beam collimation and halo control were studied as an option to complementmore » the collimation system for the upgrades of the Large Hadron Collider (LHC) at CERN; a conceptual design was recently completed. Because of their electric charge and the absence of materials close to the proton beam, electron lenses may also provide an alternative to wires for long-range beam-beam compensation in LHC luminosity upgrade scenarios with small crossing angles. At Fermilab, we are planning to install an electron lens in the Integrable Optics Test Accelerator (IOTA, a 40-m ring for 150-MeV electrons) as one of the proof-of-principle implementations of nonlinear integrable optics to achieve large tune spreads and more stable beams without loss of dynamic aperture.« less

  6. SU-F-T-527: A Novel Dynamic Multileaf Collimator Leaf-Sequencing Algorithm in Radiation Therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jing, J; Lin, H; Chow, J

    Purpose: A novel leaf-sequencing algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimator (MLC). The efficiency of this dynamic MLC leaf-sequencing method was evaluated using external beam treatment plans delivered by intensity modulated radiation therapy technique. Methods: To qualify and validate this algorithm, integral test for the beam segment of MLC generated by the CORVUS treatment planning system was performed with clinical intensity map experiments. The treatment plans were optimized and the fluence maps for all photon beams were determined. This algorithm started with the algebraic expression for the area under the beammore » profile. The coefficients in the expression can be transformed into the specifications for the leaf-setting sequence. The leaf optimization procedure was then applied and analyzed for clinical relevant intensity profiles in cancer treatment. Results: The macrophysical effect of this method can be described by volumetric plan evaluation tools such as dose-volume histograms (DVHs). The DVH results are in good agreement compared to those from the CORVUS treatment planning system. Conclusion: We developed a dynamic MLC method to examine the stability of leaf speed including effects of acceleration and deceleration of leaf motion in order to make sure the stability of leaf speed did not affect the intensity profile generated. It was found that the mechanical requirements were better satisfied using this method. The Project is sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry.« less

  7. Poster - Thur Eve - 77: Coordinate transformation from DICOM to DOSXYZnrc.

    PubMed

    Zhan, L; Jiang, R; Osei, E K

    2012-07-01

    DICOM format is the de facto standard for communications between therapeutic and diagnostic modalities. A plan generated by a treatment planning system (TPS) is often exported to DICOM format. BEAMnrc/DOSXYZnrc is a widely used Monte Carlo (MC) package for beam and dose simulations in radiotherapy. It has its own definition for beam orientation, which is not in compliance with the one defined in DICOM standard. Dose simulations using TPS generated plans require transformation of beam orientations to DOSXYZnrc coordinate system (c.s.) after extracting the necessary parameters from DICOM RP files. The transformation is nontrivial. There have been two studies for the coordinate transformations. The transformation equation sets derived have been helpful to BEAMnrc/DOSXYZnrc users. However, both the transformation equation sets are complex mathematically and not easy to program. In this study, we derive a new set of transformation equations, which are more compact, better understandable, and easier for computational implementation. The derivation of polar angle θ and azimuthal angle φ is similar to the existing studies by applying a series of rotations to a vector in DICOM patient c.s. The derivation of beam rotation Φ col for DOSXYZnrc, however, is different. It is obtained by a direct combination of the actual collimator rotation with the projection of the couch rotation to the collimator rotating plane. Verification of the transformation has been performed using clinical plans created with Eclipse. The comparison between Eclipse and MC results show exact geometrical agreement for field placements, together with good agreement in dose distributions. © 2012 American Association of Physicists in Medicine.

  8. Beam coordinate transformations from DICOM to DOSXYZnrc

    NASA Astrophysics Data System (ADS)

    Zhan, Lixin; Jiang, Runqing; Osei, Ernest K.

    2012-12-01

    Digital imaging and communications in medicine (DICOM) format is the de facto standard for communications between therapeutic and diagnostic modalities. A plan generated by a treatment planning system (TPS) is often exported in DICOM format. BEAMnrc/DOSXYZnrc is a widely used Monte Carlo (MC) package for modelling the Linac head and simulating dose delivery in radiotherapy. It has its own definition of beam orientation, which is not in compliance with the one defined in the DICOM standard. MC dose calculations using information from TPS generated plans require transformation of beam orientations to the DOSXYZnrc coordinate system (c.s.) and the transformation is non-trivial. There have been two studies on the coordinate transformations. The transformation equation sets derived have been helpful to BEAMnrc/DOSXYZnrc users. However, the transformation equation sets are complex mathematically and not easy to program. In this study, we derive a new set of transformation equations, which are more compact, easily understandable, and easier for computational implementation. The derivation of the polar angle θ and the azimuthal angle φ used by DOSXYZnrc is similar to the existing studies by applying a series of rotations to a vector in DICOM patient c.s. The derivation of the beam rotation ϕcol for DOSXYZnrc, however, is different. It is obtained by a direct combination of the actual collimator rotation with the projection of the couch rotation to the collimator rotating plane. Verification of the transformation has been performed using clinical plans. The comparisons between TPS and MC results show very good geometrical agreement for field placements, together with good agreement in dose distributions.

  9. TH-AB-BRA-12: Experimental Results From the First High-Field Inline MRI-Linac

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keall, P; Dong, B; Zhang, K

    Purpose: The pursuit of real-time image guided radiotherapy using optimal tissue contrast has seen the development of several hybrid MRI-treatment systems, high field and low field, and inline and perpendicular configurations. As part of a new MRI-Linac program, an MRI scanner was integrated with a linear accelerator to enable investigations of a coupled inline MRI-Linac system. This work describes our experimental results from the first high-field inline MRI-Linac. Methods: A 1.5 Tesla magnet (Sonata, Siemens) was located in a purpose built RF cage enabling shielding from and close proximity to a linear accelerator with inline orientation. A portable linear acceleratormore » (Linatron, Varian) was installed together with a multi-leaf collimator (Millennium, Varian) to provide dynamic field collimation and the whole assembly built onto a stainless-steel rail system. A series of MRI-Linac experiments was performed to investigate: (1) image quality with beam on measured using a macropodine (kangaroo) ex vivo phantom; (2) the noise as a function of beam state measured using a 6-channel surface coil array and; (3) electron focusing measured using GafChromic film. Results: (1) The macropodine phantom image quality with the beam on was almost identical to that with the beam off. (2) Noise measured with a surface RF coil produced a 25% elevation of background noise when the radiation beam was on. (3) Film measurements demonstrated electron focusing occurring at the center of the radiation field. Conclusion: The first high-field MRI-Linac has been built and experimentally characterized. This system has allowed us to establish the efficacy of a high field in-line MRI-Linac and study a number of the technical challenges and solutions. Supported by the Australian National Health and Medical Research Council, the Australian Research Council, the Australian Cancer Research Foundation and the Health and Hospitals Fund.« less

  10. Design of collimating and rearrangement systems of laser diode array beam

    NASA Astrophysics Data System (ADS)

    Gao, Runmei; Fang, Tao; Fu, Rulian; Yao, Jianquan

    2015-10-01

    To improve the laser diode output beam quality, micro-cylindrical lens and the step-type lens combination are designed. The former is used to collimate beam in fast-axis direction, while the latter plays a role in the slow-axis of splitting and the rearrangement. The micro-column semi-elliptical lens is made with the drops of spherical zoom lensin electric field and with the help of the material properties of light-cured production, which can reduce the reflection of the front surface and total reflection loss of the after. The divergence angle in the fast axis is compressed to roughly the same as that in the slow-axis direction; Stepped lens splits compressed long strip beam in the slow axis, with parallelogram style of level equidistant and rearrange in the fast axis direction. The spot in the slow axis gets smaller and the spot becomes larger in the fast axis. At last divergence angle and the beam spot achieve balanced in the fast axis and slow axis, optical parameters BPP integrates approximate the same, and beam quality can be improved.

  11. Toward improved target conformity for two spot scanning proton therapy delivery systems using dynamic collimation

    PubMed Central

    Moignier, Alexandra; Gelover, Edgar; Smith, Blake R.; Wang, Dongxu; Flynn, Ryan T.; Kirk, Maura L.; Lin, Liyong; Solberg, Timothy D.; Lin, Alexander; Hyer, Daniel E.

    2016-01-01

    Purpose: To quantify improvement in target conformity in brain and head and neck tumor treatments resulting from the use of a dynamic collimation system (DCS) with two spot scanning proton therapy delivery systems (universal nozzle, UN, and dedicated nozzle, DN) with median spot sizes of 5.2 and 3.2 mm over a range of energies from 100 to 230 MeV. Methods: Uncollimated and collimated plans were calculated with both UN and DN beam models implemented within our in-house treatment planning system for five brain and ten head and neck datasets in patients previously treated with spot scanning proton therapy. The prescription dose and beam angles from the clinical plans were used for both the UN and DN plans. The average reduction of the mean dose to the 10-mm ring surrounding the target between the uncollimated and collimated plans was calculated for the UN and the DN. Target conformity was analyzed using the mean dose to 1-mm thickness rings surrounding the target at increasing distances ranging from 1 to 10 mm. Results: The average reductions of the 10-mm ring mean dose for the UN and DN plans were 13.7% (95% CI: 11.6%–15.7%; p < 0.0001) and 11.5% (95% CI: 9.5%–13.5%; p < 0.0001) across all brain cases and 7.1% (95% CI: 4.4%–9.8%; p < 0.001) and 6.3% (95% CI: 3.7%–9.0%; p < 0.001), respectively, across all head and neck cases. The collimated UN plans were either more conformal (all brain cases and 60% of the head and neck cases) than or equivalent (40% of the head and neck cases) to the uncollimated DN plans. The collimated DN plans offered the highest conformity. Conclusions: The DCS added either to the UN or DN improved the target conformity. The DCS may be of particular interest for sites with UN systems looking for a more economical solution than upgrading the nozzle to improve the target conformity of their spot scanning proton therapy system. PMID:26936726

  12. All-reflective optical target illumination system with high numerical aperture

    DOEpatents

    Sigler, Robert D.

    1978-01-01

    An all-reflective optical system for providing illumination of a target focal region at high numerical aperture from a pair of co-axially, confluent collimated light beams. A target cavity is defined by a pair of opposed inner ellipsoidal reflectors having respective first focal points within a target region and second focal points at a vertex opening in the opposing reflector. Outwardly of each inner reflector is the opposed combination of a spherical reflector, and an outer generally ellipsoidal reflector having an aberrated first focal point coincident with the focus of the opposing spherical reflector and a second focal point coincident with the second focal point of the opposing inner ellipsoidal reflector through a vertex opening in the spherical reflector. The confluent collimated beams are incident through vertex openings in the outer ellipsoidal reflectors onto respective opposing spherical reflectors. Each beam is reflected by the associated spherical reflector onto the opposing outer ellipsoidal reflector and focused thereby onto the opposing inner ellipsoidal reflector, and then onto the target region.

  13. Automated assembly of fast-axis collimation (FAC) lenses for diode laser bar modules

    NASA Astrophysics Data System (ADS)

    Miesner, Jörn; Timmermann, Andre; Meinschien, Jens; Neumann, Bernhard; Wright, Steve; Tekin, Tolga; Schröder, Henning; Westphalen, Thomas; Frischkorn, Felix

    2009-02-01

    Laser diodes and diode laser bars are key components in high power semiconductor lasers and solid state laser systems. During manufacture, the assembly of the fast axis collimation (FAC) lens is a crucial step. The goal of our activities is to design an automated assembly system for high volume production. In this paper the results of an intermediate milestone will be reported: a demonstration system was designed, realized and tested to prove the feasibility of all of the system components and process features. The demonstration system consists of a high precision handling system, metrology for process feedback, a powerful digital image processing system and tooling for glue dispensing, UV curing and laser operation. The system components as well as their interaction with each other were tested in an experimental system in order to glean design knowledge for the fully automated assembly system. The adjustment of the FAC lens is performed by a series of predefined steps monitored by two cameras concurrently imaging the far field and the near field intensity distributions. Feedback from these cameras processed by a powerful and efficient image processing algorithm control a five axis precision motion system to optimize the fast axis collimation of the laser beam. Automated cementing of the FAC to the diode bar completes the process. The presentation will show the system concept, the algorithm of the adjustment as well as experimental results. A critical discussion of the results will close the talk.

  14. Imaging electron flow from collimating contacts in graphene

    NASA Astrophysics Data System (ADS)

    Bhandari, S.; Lee, G. H.; Watanabe, K.; Taniguchi, T.; Kim, P.; Westervelt, R. M.

    2018-04-01

    The ballistic motion of electrons in graphene opens exciting opportunities for electron-optic devices based on collimated electron beams. We form a collimating contact in a hBN-encapsulated graphene hall bar by adding zigzag contacts on either side of an electron emitter that absorb stray electrons; collimation can be turned off by floating the zig-zag contacts. The electron beam is imaged using a liquid-He cooled scanning gate microscope (SGM). The tip deflects electrons as they pass from the collimating contact to a receiving contact on the opposite side of the channel, and an image of electron flow can be made by displaying the change in transmission as the tip is raster scanned across the sample. The angular half width Δθ of the electron beam is found by applying a perpendicular magnetic field B that bends electron paths into cyclotron orbits. The images reveal that the electron flow from the collimating contact drops quickly at B  =  0.05 T when the electron orbits miss the receiving contact. The flow for the non-collimating case persists longer, up to B  =  0.19 T, due to the broader range of entry angles. Ray-tracing simulations agree well with the experimental images. By fitting the fields B at which the magnitude of electron flow drops in the experimental SGM images, we find Δθ  =  9° for electron flow from the collimating contact, compared with Δθ  =  54° for the non-collimating case.

  15. Bent silicon strip crystals for high-energy charged particle beam collimation

    NASA Astrophysics Data System (ADS)

    Germogli, G.; Mazzolari, A.; Guidi, V.; Romagnoni, M.

    2017-07-01

    For applications in high energy particles accelerators, such as the crystal-assisted beam collimation, several strip crystals exploiting anticlastic curvature were produced in the last decade at the Sensor and Semiconductor Laboratory (SSL) of Ferrara by means of revisited techniques for silicon micromachining, such as photolitography and wet etching. Those techniques were recently enhanced by introducing a further treatment called Magnetorheological Finishing (MRF), which allowed to fabricate crystals with ultraflat surface and miscut very close to zero. The technology of the mechanical devices used to hold and bend crystals has been also improved by employing a titanium alloy to realize the holders. Characterization method were also improved: the usage of a high resolution X-rays diffractometer was introduced to directly measure crystal bending and torsion. Accuracy of the diffractometer was furtherly enhanced with an autocollimator, which found an important application in miscut characterization. A new infrared light interferometer was used to map the thickness of the starting swafers with sub-micrometric precision, as well as to measure the length along the beam of the strips. Crystals were characterized at the H8 external lines of CERN-SPS with various hundreds-GeV ion beams, which gave results in agreement with the precharacterization performed at SSL. One strip was selected among the crystals to be installed in the LHC beam pipe during the Long Shutdown 1 in 2014. These crystals were very recently tested in a crystal-assisted collimation experiment with a 6.5 TeV proton beam, resulting in the first observation of channeling at this record energy, being also the first observation of channeling of the beam circulating in the LHC.

  16. Solar concentrator with integrated tracking and light delivery system with summation

    DOEpatents

    Maxey, Lonnie Curt

    2015-05-05

    A solar light distribution system includes a solar light concentrator that is affixed externally to a light transfer tube. Solar light waves are processed by the concentrator into a collimated beam of light, which is then transferred through a light receiving port and into the light transfer tube. A reflector redirects the collimated beam of light through the tube to a light distribution port. The interior surface of the light transfer tube is highly reflective so that the light transfers through the tube with minimal losses. An interchangeable luminaire is attached to the light distribution port and provides light inside of a structure. A sun tracking device rotates the concentrator and the light transfer tube to optimize the receiving of solar light by the concentrator throughout the day. The system provides interior lighting that uses only renewable energy sources, and releases no carbon dioxide emissions into the atmosphere.

  17. Device and method for generating a beam of acoustic energy from a borehole, and applications thereof

    DOEpatents

    Vu, Cung Khac; Sinha, Dipen N; Pantea, Cristian; Nihei, Kurt T; Schmitt, Denis P; Skelt, Christopher

    2013-10-01

    In some aspects of the invention, a method of generating a beam of acoustic energy in a borehole is disclosed. The method includes generating a first acoustic wave at a first frequency; generating a second acoustic wave at a second frequency different than the first frequency, wherein the first acoustic wave and second acoustic wave are generated by at least one transducer carried by a tool located within the borehole; transmitting the first and the second acoustic waves into an acoustically non-linear medium, wherein the composition of the non-linear medium produces a collimated beam by a non-linear mixing of the first and second acoustic waves, wherein the collimated beam has a frequency based upon a difference between the first frequency and the second frequency; and transmitting the collimated beam through a diverging acoustic lens to compensate for a refractive effect caused by the curvature of the borehole.

  18. Characterization of X-Ray Diffraction System with a Microfocus X-Ray Source and a Polycapillary Optic

    NASA Technical Reports Server (NTRS)

    Gubarev, Mikhail; Marshall, Joy K.; Ciszak, Ewa; Ponomarev, Igor

    2000-01-01

    We present here an optimized microfocus x-ray source and polycapillary optic system designed for diffraction of small protein crystals. The x-ray beam is formed by a 5.5mm focal length capillary collimator coupled with a 40 micron x-ray source operating at 46Watts. Measurements of the x-ray flux, the divergence and the spectral characteristics of the beam are presented, This optimized system provides a seven fold greater flux than our recently reported configuration [M. Gubarev, et al., J. of Applied Crystallography (2000) 33, in press]. We now make a comparison with a 5kWatts rotating anode generator (Rigaku) coupled with confocal multilayer focusing mirrors (Osmic, CMF12- 38Cu6). The microfocus x-ray source and polycapillary collimator system delivers 60% of the x-ray flux from the rotating anode system. Additional ways to improve our microfocus x-ray system, and thus increase the x-ray flux will be discussed.

  19. Acoustic logic gates and Boolean operation based on self-collimating acoustic beams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Ting; Xu, Jian-yi; Cheng, Ying, E-mail: chengying@nju.edu.cn

    2015-03-16

    The reveal of self-collimation effect in two-dimensional (2D) photonic or acoustic crystals has opened up possibilities for signal manipulation. In this paper, we have proposed acoustic logic gates based on the linear interference of self-collimated beams in 2D sonic crystals (SCs) with line-defects. The line defects on the diagonal of the 2D square SCs are actually functioning as a 3 dB splitter. By adjusting the phase difference between two input signals, the basic Boolean logic functions such as XOR, OR, AND, and NOT are achieved both theoretically and experimentally. Due to the non-diffracting property of self-collimation beams, more complex Boolean logicmore » and algorithms such as NAND, NOR, and XNOR can be realized by cascading the basic logic gates. The achievement of acoustic logic gates and Boolean operation provides a promising approach for acoustic signal computing and manipulations.« less

  20. Detector-specific correction factors in radiosurgery beams and their impact on dose distribution calculations.

    PubMed

    García-Garduño, Olivia A; Rodríguez-Ávila, Manuel A; Lárraga-Gutiérrez, José M

    2018-01-01

    Silicon-diode-based detectors are commonly used for the dosimetry of small radiotherapy beams due to their relatively small volumes and high sensitivity to ionizing radiation. Nevertheless, silicon-diode-based detectors tend to over-respond in small fields because of their high density relative to water. For that reason, detector-specific beam correction factors ([Formula: see text]) have been recommended not only to correct the total scatter factors but also to correct the tissue maximum and off-axis ratios. However, the application of [Formula: see text] to in-depth and off-axis locations has not been studied. The goal of this work is to address the impact of the correction factors on the calculated dose distribution in static non-conventional photon beams (specifically, in stereotactic radiosurgery with circular collimators). To achieve this goal, the total scatter factors, tissue maximum, and off-axis ratios were measured with a stereotactic field diode for 4.0-, 10.0-, and 20.0-mm circular collimators. The irradiation was performed with a Novalis® linear accelerator using a 6-MV photon beam. The detector-specific correction factors were calculated and applied to the experimental dosimetry data for in-depth and off-axis locations. The corrected and uncorrected dosimetry data were used to commission a treatment planning system for radiosurgery planning. Various plans were calculated with simulated lesions using the uncorrected and corrected dosimetry. The resulting dose calculations were compared using the gamma index test with several criteria. The results of this work presented important conclusions for the use of detector-specific beam correction factors ([Formula: see text] in a treatment planning system. The use of [Formula: see text] for total scatter factors has an important impact on monitor unit calculation. On the contrary, the use of [Formula: see text] for tissue-maximum and off-axis ratios has not an important impact on the dose distribution calculation by the treatment planning system. This conclusion is only valid for the combination of treatment planning system, detector, and correction factors used in this work; however, this technique can be applied to other treatment planning systems, detectors, and correction factors.

  1. Design and characteristic analysis of shaping optics for optical trepanning

    NASA Astrophysics Data System (ADS)

    Zeng, D.; Latham, W. P.; Kar, A.

    2005-08-01

    Optical trepanning is a new laser drilling method using an annular beam. The annular beams allow numerous irradiance profiles to supply laser energy to the workpiece and thus provide more flexibility in affecting the hole quality than a traditional circular laser beam. The refractive axicon system has been designed to generating a collimated annular beam. In this article, calculations of intensity distributions produced by this refractive system are made by evaluating the Kirchhoff-Fresnel diffraction. It is shown that the refractive system is able to transform a Gaussian beam into a full Gaussian annular beam. The base angle of the axicon lens, input laser beam diameter and intensity profiles are found to be important factors for the axcion refractive system. Their effects on the annular beam profiles are analyzed based on the numerical solutions of the diffraction patterns.

  2. Development of a Multileaf Collimator for Proton Radiotherapy

    DTIC Science & Technology

    2010-06-01

    generated and compared to the dosimetry derived from radiochromic media. TLDS may be inserted into the phantom to further confirm the technique. Finally...of dosimetry systems for scanned beams: (FY 2006-2009). We are investigating dosimetry systems for use with scanned beams and will either purchase a...group Research in Monte Carlo Simulations and Dosimetry Studies of Proton Therapy Rulon Mayer, PhD Energetic protons used to damage tumors

  3. Geometric beam coupling impedance of LHC secondary collimators

    NASA Astrophysics Data System (ADS)

    Frasciello, Oscar; Tomassini, Sandro; Zobov, Mikhail; Salvant, Benoit; Grudiev, Alexej; Mounet, Nicolas

    2016-02-01

    The High Luminosity LHC project is aimed at increasing the LHC luminosity by an order of magnitude. One of the key ingredients to achieve the luminosity goal is the beam intensity increase. In order to keep beam instabilities under control and to avoid excessive power losses a careful design of new vacuum chamber components and an improvement of the present LHC impedance model are required. Collimators are among the major impedance contributors. Measurements with beam have revealed that the betatron coherent tune shifts were higher by about a factor of 2 with respect to the theoretical predictions based on the LHC impedance model up to 2012. In that model the resistive wall impedance has been considered as the dominating impedance contribution for collimators. By carefully simulating also their geometric impedance we have contributed to the update of the LHC impedance model, reaching also a better agreement between the measured and simulated betatron tune shifts. During the just ended LHC Long Shutdown I (LSI), TCS/TCT collimators were replaced by new devices embedding BPMs and TT2-111R ferrite blocks. We present here preliminary estimations of their broad-band impedance, showing that an increase of about 20% is expected in the kick factors with respect to previous collimators without BPMs.

  4. First Attempts at using Active Halo Control at the LHC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wagner, Joschka; Bruce, Roderik; Garcia Morales, Hector

    2016-06-01

    The beam halo population is a non-negligible factor for the performance of the LHC collimation system and the machine protection. In particular this could become crucial for aiming at stored beam energies of 700 MJ in the High Luminosity (HL-LHC) project, in order to avoid beam dumps caused by orbit jitter and to ensure safety during a crab cavity failure. Therefore several techniques to safely deplete the halo, i.e. active halo control, are under development. In a first attempt a novel way for safe halo depletion was tested with particle narrow-band excitation employing the LHC Transverse Damper (ADT). At anmore » energy of 450 GeV a bunch selective beam tail scraping without affecting the core distribution was attempted. This paper presents the first measurement results, as well as a simple simulation to model the underlying dynamics.« less

  5. NLC Special Projects

    Science.gov Websites

    Measurement (with NLC RF group) LCLS and related technologies (LCLS work related to NLC work) Collimation Systems (with Beam Delivery group) Combined Laser System (with NLC sources group) Polarized Positron Sources (with NLC sources group) Crab Cavity Phase Control System Timing and RF distribution System (with

  6. Design considerations for a computer controlled multileaf collimator for the Harper Hospital fast neutron therapy facility.

    PubMed

    Maughan, Richard L; Yudelev, Mark; Aref, Amr; Chuba, Paul J; Forman, Jeffrey; Blosser, Emanuel J; Horste, Timothy

    2002-04-01

    The d(48.5) + Be neutron beam from the Harper Hospital superconducting cyclotron is collimated using a unique multirod collimator (MRC). A computer controlled multileaf collimator (MLC) is being designed to improve efficiency and allow for the future development of intensity modulated radiation therapy with neutrons. For the current study the use of focused or unfocused collimator leaves has been studied. Since the engineering effort associated with the leaf design and materials choice impacts significantly on cost, it was desirable to determine the clinical impact of using unfocused leaves in the MLC design. The MRC is a useful tool for studying the effects of using focused versus unfocused beams on beam penumbra. The effects of the penumbra for the different leaf designs on tumor and normal tissue DVHs in two selected sites (prostate and head and neck) was investigated. The increase in the penumbra resulting from using unfocused beams was small (approximately 1.5 mm for a 5 x 5 cm2 field and approximately 7.6 mm for a 25 x 25 cm2 field at 10 cm depth) compared to the contribution of phantom scatter to the penumbra width (5.4 and 20 mm for the small and large fields at 10 cm depth, respectively). Comparison of DVHs for tumor and critical normal tissue in a prostate and head and neck case showed that the dosimetric disadvantages of using an unfocused rather than focused beam were minimal and only significant at shallow depths. For the rare cases, where optimum penumbra conditions are required, a MLC incorporating tapered leaves and, thus, providing focused collimation in one plane is necessary.

  7. On the use of an analytic source model for dose calculations in precision image-guided small animal radiotherapy.

    PubMed

    Granton, Patrick V; Verhaegen, Frank

    2013-05-21

    Precision image-guided small animal radiotherapy is rapidly advancing through the use of dedicated micro-irradiation devices. However, precise modeling of these devices in model-based dose-calculation algorithms such as Monte Carlo (MC) simulations continue to present challenges due to a combination of very small beams, low mechanical tolerances on beam collimation, positioning and long calculation times. The specific intent of this investigation is to introduce and demonstrate the viability of a fast analytical source model (AM) for use in either investigating improvements in collimator design or for use in faster dose calculations. MC models using BEAMnrc were developed for circular and square fields sizes from 1 to 25 mm in diameter (or side) that incorporated the intensity distribution of the focal spot modeled after an experimental pinhole image. These MC models were used to generate phase space files (PSFMC) at the exit of the collimators. An AM was developed that included the intensity distribution of the focal spot, a pre-calculated x-ray spectrum, and the collimator-specific entrance and exit apertures. The AM was used to generate photon fluence intensity distributions (ΦAM) and PSFAM containing photons radiating at angles according to the focal spot intensity distribution. MC dose calculations using DOSXYZnrc in a water and mouse phantom differing only by source used (PSFMC versus PSFAM) were found to agree within 7% and 4% for the smallest 1 and 2 mm collimator, respectively, and within 1% for all other field sizes based on depth dose profiles. PSF generation times were approximately 1200 times faster for the smallest beam and 19 times faster for the largest beam. The influence of the focal spot intensity distribution on output and on beam shape was quantified and found to play a significant role in calculated dose distributions. Beam profile differences due to collimator alignment were found in both small and large collimators sensitive to shifts of 1 mm with respect to the central axis.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sudhyadhom, A; McGuinness, C; Descovich, M

    Purpose: To develop a methodology for validation of a Monte-Carlo dose calculation model for robotic small field SRS/SBRT deliveries. Methods: In a robotic treatment planning system, a Monte-Carlo model was iteratively optimized to match with beam data. A two-part analysis was developed to verify this model. 1) The Monte-Carlo model was validated in a simulated water phantom versus a Ray-Tracing calculation on a single beam collimator-by-collimator calculation. 2) The Monte-Carlo model was validated to be accurate in the most challenging situation, lung, by acquiring in-phantom measurements. A plan was created and delivered in a CIRS lung phantom with film insert.more » Separately, plans were delivered in an in-house created lung phantom with a PinPoint chamber insert within a lung simulating material. For medium to large collimator sizes, a single beam was delivered to the phantom. For small size collimators (10, 12.5, and 15mm), a robotically delivered plan was created to generate a uniform dose field of irradiation over a 2×2cm{sup 2} area. Results: Dose differences in simulated water between Ray-Tracing and Monte-Carlo were all within 1% at dmax and deeper. Maximum dose differences occurred prior to dmax but were all within 3%. Film measurements in a lung phantom show high correspondence of over 95% gamma at the 2%/2mm level for Monte-Carlo. Ion chamber measurements for collimator sizes of 12.5mm and above were within 3% of Monte-Carlo calculated values. Uniform irradiation involving the 10mm collimator resulted in a dose difference of ∼8% for both Monte-Carlo and Ray-Tracing indicating that there may be limitations with the dose calculation. Conclusion: We have developed a methodology to validate a Monte-Carlo model by verifying that it matches in water and, separately, that it corresponds well in lung simulating materials. The Monte-Carlo model and algorithm tested may have more limited accuracy for 10mm fields and smaller.« less

  9. Pin diode calibration - beam overlap monitoring for low energy cooling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Drees, A.; Montag, C.; Thieberger, P.

    2015-09-30

    We were trying to address the question whether or not the Pin Diodes, currently installed approximately 1 meter downstream of the RHIC primary collimators, are suitable to monitor a recombination signal from the future RHIC low energy cooling section. A maximized recombination signal, with the Au+78 ions being lost on the collimator, will indicate optimal Au-electron beam overlap as well as velocity matching of the electron beam in the cooling section.

  10. Sci-Thur PM – Brachytherapy 05: Surface Collimation Applied to Superficial Flap High Dose-Rate Brachytherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Derek; Sabondjian, Eric; Lawrence, Kailin

    Purpose: To apply surface collimation for superficial flap HDR skin brachytherapy utilizing common clinical resources and to demonstrate the potential for OAR dose reduction within a clinically relevant setting. Methods: Two phantom setups were used. 3 mm lead collimation was applied to a solid slab phantom to determine appropriate geometries relating to collimation and dwell activation. The same collimation was applied to the temple of an anthropomorphic head phantom to demonstrate lens dose reduction. Each setup was simulated and planned to deliver 400 cGy to a 3 cm circular target to 3 mm depth. The control and collimated irradiations weremore » sequentially measured using calibrated radiochromic films. Results: Collimation for the slab phantom attenuated the dose beyond the collimator opening, decreasing the fall-off distances by half and reducing the area of healthy skin irradiated. Target coverage can be negatively impacted by a tight collimation margin, with the required margin approximated by the primary beam geometric penumbra. Surface collimation applied to the head phantom similarly attenuated the surrounding normal tissue dose while reducing the lens dose from 84 to 68 cGy. To ensure consistent setup between simulation and treatment, additional QA was performed including collimator markup, accounting for collimator placement uncertainties, standoff distance verification, and in vivo dosimetry. Conclusions: Surface collimation was shown to reduce normal tissue dose without compromising target coverage. Lens dose reduction was demonstrated on an anthropomorphic phantom within a clinical setting. Additional QA is proposed to ensure treatment fidelity.« less

  11. Expanded beam non-imaging fiber optic connector

    DOEpatents

    Jannson, T.; Jannson, J.; Yeung, P.

    1990-02-06

    There is disclosed an expanded beam fiber to fiber connector, based on non-imaging optic principles for coupling light beams from one optical fiber to another. The system consists of two identical connector parts, referred to herein as a collimating part and a concentrating part, each having a preferred partially curved reflective boundary surface for minimizing power loss and surrounding either a hollow space or a space filled with a uniform transparent medium. In one embodiment the boundary is metallic while in a second embodiment the boundary is in the form of an interface allowing total internal reflection. In both the hollow and filled case a lens may be located at the expanded end of both the collimator part and the concentrator part forming the connector. The connector is preferably located in a housing in order to protect and preserve the mechanical stability of the coupler. 13 figs.

  12. An automatic alignment system for measuring optical path of transmissometer based on light beam scanning

    NASA Astrophysics Data System (ADS)

    Zhou, Shudao; Ma, Zhongliang; Wang, Min; Peng, Shuling

    2018-05-01

    This paper proposes a novel alignment system based on the measurement of optical path using a light beam scanning mode in a transmissometer. The system controls both the probe beam and the receiving field of view while scanning in two vertical directions. The system then calculates the azimuth angle of the transmitter and the receiver to determine the precise alignment of the optical path. Experiments show that this method can determine the alignment angles in less than 10 min with errors smaller than 66 μrad in the azimuth. This system also features high collimation precision, process automation and simple installation.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gromov, R.; Bailey, J.; Virgo, M.

    Argonne National Laboratory, in cooperation with Los Alamos National Laboratory, is developing technology with NorthStar Medical Technologies to produce 99Mo from the γ,n reaction on a 100Mo target in an electron accelerator. During production runs and thermal testing of the helium-cooled target, it became obvious that a production-scale beam-line configuration would need a collimator to protect the target from accidental beam misplacement or a beam-profile change. A prototype high-power collimator and beam stop were designed and fabricated. Testing indicated that they will be able to operate at full power in the production-scale accelerator.

  14. Measurements and simulations of boron carbide as degrader material for proton therapy.

    PubMed

    Gerbershagen, Alexander; Baumgarten, Christian; Kiselev, Daniela; van der Meer, Robert; Risters, Yannic; Schippers, Marco

    2016-07-21

    We report on test measurements using boron carbide (B4C) as degrader material in comparison with the conventional graphite, which is currently used in many proton therapy degraders. Boron carbide is a material of lower average atomic weight and higher density than graphite. Calculations predict that, compared to graphite, the use of boron carbide results in a lower emittance behind the degrader due to the shorter degrader length. Downstream of the acceptance defining collimation system we expect a higher beam transmission, especially at low beam energies. This is of great interest in proton therapy applications as it allows either a reduction of the beam intensity extracted from the cyclotron leading to lower activation or a reduction of the treatment time. This paper summarizes the results of simulations and experiments carried out at the PROSCAN facility at the Paul Scherrer Institute(1). The simulations predict an increase in the transmitted beam current after the collimation system of approx. 30.5% for beam degradation from 250 to 84 MeV for a boron carbide degrader compared to graphite. The experiment carried out with a boron carbide block reducing the energy to 84 MeV yielded a transmission improvement of 37% compared with the graphite degrader set to that energy.

  15. High-resolution field shaping utilizing a masked multileaf collimator.

    PubMed

    Williams, P C; Cooper, P

    2000-08-01

    Multileaf collimators (MLCs) have become an important tool in the modern radiotherapy department. However, the current limit of resolution (1 cm at isocentre) can be too coarse for acceptable shielding of all fields. A number of mini- and micro-MLCs have been developed, with thinner leaves to achieve approved resolution. Currently however, such devices are limited to modest field sizes and stereotactic applications. This paper proposes a new method of high-resolution beam collimation by use of a tertiary grid collimator situated below the conventional MLC. The width of each slit in the grid is a submultiple of the MLC width. A composite shaped field is thus built up from a series of subfields, with the main MLC defining the length of each strip within each subfield. Presented here are initial findings using a prototype device. The beam uniformity achievable with such a device was examined by measuring transmission profiles through the grid using a diode. Profiles thus measured were then copied and superposed to generate composite beams, from which the uniformity achievable could be assessed. With the average dose across the profile normalized to 100%, hot spots up to 5.0% and troughs of 3% were identified for a composite beam of 2 x 5.0 mm grids, as measured at Dmax for a 6 MV beam. For a beam composed from 4 x 2.5 mm grids, the maximum across the profile was 3.0% above the average, and the minimum 2.5% below. Actual composite profiles were also formed using the integrating properties of film, with the subfield indexing performed using an engineering positioning stage. The beam uniformity for these fields compared well with that achieved in theory using the diode measurements. Finally sine wave patterns were generated to demonstrate the potential improvements in field shaping and conformity using this device as opposed to the conventional MLC alone. The scalloping effect on the field edge commonly seen on MLC fields was appreciably reduced by use of 2 x 5.0 mm grids, and still further by the use of 4 x 2.5 mm grids, as would be expected. This was also achieved with a small or negligible broadening of the beam penumbra as measured at Dmax.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Verburg, J; Bortfeld, T

    Purpose: We present a new system to perform prompt gamma-ray spectroscopy during proton pencil-beam scanning treatments, which enables in vivo verification of the proton range. This system will be used for the first clinical studies of this technology. Methods: After successful pre-clinical testing of prompt gamma-ray spectroscopy, a full scale system for clinical studies is now being assembled. Prompt gamma-rays will be detected during patient treatment using an array of 8 detector modules arranged behind a tungsten collimator. Each detector module consists of a lanthanum(III) bromide scintillator, a photomultiplier tube, and custom electronics for stable high voltage supply and signalmore » amplification. A new real-time data acquisition and control system samples the signals from the detectors with analog-to-digital converters, analyses events of interest, and communicates with the beam delivery systems. The timing of the detected events was synchronized to the cyclotron radiofrequency and the pencil-beam delivery. Range verification is performed by matching measured energy- and timeresolved gamma-ray spectra to nuclear reaction models based on the clinical treatment plan. Experiments in phantoms were performed using clinical beams in order to assess the performance of the systems. Results: The experiments showed reliable real-time analysis of more than 10 million detector events per second. The individual detector modules acquired accurate energy- and time-resolved gamma-ray measurements at a rate of 1 million events per second, which is typical for beams delivered with a clinical dose rate. The data acquisition system successfully tracked the delivery of the scanned pencil-beams to determine the location of range deviations within the treatment field. Conclusion: A clinical system for proton range verification using prompt gamma-ray spectroscopy has been designed and is being prepared for use during patient treatments. We anticipate to start a first clinical study in the near future. This work was supported by the Federal Share of program income earned by Massachusetts; General Hospital on C06-CA059267, Proton Therapy Research and Treatment Center.« less

  17. Development of the radial neutron camera system for the HL-2A tokamak

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Y. P., E-mail: zhangyp@swip.ac.cn; Yang, J. W.; Liu, Yi

    2016-06-15

    A new radial neutron camera system has been developed and operated recently in the HL-2A tokamak to measure the spatial and time resolved 2.5 MeV D-D fusion neutron, enhancing the understanding of the energetic-ion physics. The camera mainly consists of a multichannel collimator, liquid-scintillation detectors, shielding systems, and a data acquisition system. Measurements of the D-D fusion neutrons using the camera have been successfully performed during the 2015 HL-2A experiment campaign. The measurements show that the distribution of the fusion neutrons in the HL-2A plasma has a peaked profile, suggesting that the neutral beam injection beam ions in the plasmamore » have a peaked distribution. It also suggests that the neutrons are primarily produced from beam-target reactions in the plasma core region. The measurement results from the neutron camera are well consistent with the results of both a standard {sup 235}U fission chamber and NUBEAM neutron calculations. In this paper, the new radial neutron camera system on HL-2A and the first experimental results are described.« less

  18. Isotopic abundance in atom trap trace analysis

    DOEpatents

    Lu, Zheng-Tian; Hu, Shiu-Ming; Jiang, Wei; Mueller, Peter

    2014-03-18

    A method and system for detecting ratios and amounts of isotopes of noble gases. The method and system is constructed to be able to measure noble gas isotopes in water and ice, which helps reveal the geological age of the samples and understand their movements. The method and system uses a combination of a cooled discharge source, a beam collimator, a beam slower and magneto-optic trap with a laser to apply resonance frequency energy to the noble gas to be quenched and detected.

  19. Gaussian versus flat-top spatial beam profiles for optical stimulation of the prostate nerves

    NASA Astrophysics Data System (ADS)

    Tozburun, Serhat; Lagoda, Gwen A.; Burnett, Arthur L.; Fried, Nathaniel M.

    2010-02-01

    The cavernous nerves (CN) course along the prostate surface and are responsible for erectile function. Improved identification and preservation of the CN's is critical to maintaining sexual potency after prostate cancer surgery. Noncontact optical nerve stimulation (ONS) of the CN's was recently demonstrated in a rat model, in vivo, as a potential alternative to electrical nerve stimulation (ENS) for identification of the CN's during prostate surgery. However, the therapeutic window for ONS is narrow, so optimal design of the fiber optic delivery system is critical for safe, reproducible stimulation. This study describes modeling, assembly, and testing of an ONS probe for delivering a small, collimated, flat-top laser beam for uniform CN stimulation. A direct comparison of the magnitude and response time of the intracavernosal pressure (ICP) for both Gaussian and flat-top spatial beam profiles was performed. Thulium fiber laser radiation (λ=1870 nm) was delivered through a 200-μm fiber, with distal fiber tip chemically etched to convert a Gaussian to flat-top beam profile. The laser beam was collimated to a 1-mm-diameter spot using an aspheric lens. Computer simulations of light propagation were used to optimize the probe design. The 10-Fr (3.4-mm-OD) laparoscopic probe provided a constant radiant exposure at the CN surface. The probe was tested in four rats, in vivo. ONS of the CN's was performed with a 1-mm-diameter spot, 5-ms pulse duration, and pulse rate of 20 Hz for a duration of 15-30 s. The flat-top laser beam profile consistently produced a faster and higher ICP response at a lower radiant exposure than the Gaussian beam profile due, in part, to easier alignment of the more uniform beam with nerve. The threshold for ONS was approximately 0.14 J/cm2, corresponding to a temperature increase of 6-8°C at the CN surface after a stimulation time of 15 s. With further development, ONS may be used as a diagnostic tool for identification of CN's during prostate cancer surgery.

  20. Miniaturized CARS microendoscope probe design for label-free intraoperative imaging

    NASA Astrophysics Data System (ADS)

    Chen, Xu; Wang, Xi; Xu, Xiaoyun; Cheng, Jie; Liu, Zhengfan; Weng, Sheng; Thrall, Michael J.; Goh, Alvin C.; McCormick, Daniel T.; Wong, Kelvin; Wong, Stephen T. C.

    2014-03-01

    A Coherent Anti-Stokes Raman Scattering (CARS) microendoscope probe for early stage label-free prostate cancer diagnosis at single cell resolution is presented. The handheld CARS microendoscope probe includes a customized micro-electromechanical systems (MEMS) scanning mirror as well as miniature optical and mechanical components. In our design, the excitation laser (pump and stokes beams) from the fiber is collimated, reflected by the reflecting mirror, and transmitted via a 2D MEMS scanning mirror and a micro-objective system onto the sample; emission in the epi-direction is returned through the micro-objective lens, MEMS and reflecting mirror, and collimation system, and finally the emission signal is collected by a photomultiplier tube (PMT). The exit pupil diameter of the collimator system is designed to match the diameter of the MEMS mirror and the entrance pupil diameter of the micro-objective system. The back aperture diameter of the micro-objective system is designed according to the largest MEMS scanning angle and the distance between the MEMS mirror and the back aperture. To increase the numerical aperture (NA) of the micro-objective system in order to enhance the signal collection efficiency, the back aperture diameter of the micro-objective system is enlarged with an upfront achromatic wide angle Keplerian telescope beam expander. The integration of a miniaturized micro-optics probe with optical fiber CARS microscopy opens up the possibility of in vivo molecular imaging for cancer diagnosis and surgical intervention.

  1. Method for dose-reduced 3D catheter tracking on a scanning-beam digital x-ray system using dynamic electronic collimation

    NASA Astrophysics Data System (ADS)

    Dunkerley, David A. P.; Funk, Tobias; Speidel, Michael A.

    2016-03-01

    Scanning-beam digital x-ray (SBDX) is an inverse geometry x-ray fluoroscopy system capable of tomosynthesis-based 3D catheter tracking. This work proposes a method of dose-reduced 3D tracking using dynamic electronic collimation (DEC) of the SBDX scanning x-ray tube. Positions in the 2D focal spot array are selectively activated to create a regionof- interest (ROI) x-ray field around the tracked catheter. The ROI position is updated for each frame based on a motion vector calculated from the two most recent 3D tracking results. The technique was evaluated with SBDX data acquired as a catheter tip inside a chest phantom was pulled along a 3D trajectory. DEC scans were retrospectively generated from the detector images stored for each focal spot position. DEC imaging of a catheter tip in a volume measuring 11.4 cm across at isocenter required 340 active focal spots per frame, versus 4473 spots in full-FOV mode. The dose-area-product (DAP) and peak skin dose (PSD) for DEC versus full field-of-view (FOV) scanning were calculated using an SBDX Monte Carlo simulation code. DAP was reduced to 7.4% to 8.4% of the full-FOV value, consistent with the relative number of active focal spots (7.6%). For image sequences with a moving catheter, PSD was 33.6% to 34.8% of the full-FOV value. The root-mean-squared-deviation between DEC-based 3D tracking coordinates and full-FOV 3D tracking coordinates was less than 0.1 mm. The 3D distance between the tracked tip and the sheath centerline averaged 0.75 mm. Dynamic electronic collimation can reduce dose with minimal change in tracking performance.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pino, R; Therriault-Proulx, F; Yang, J

    Purpose: To perform dose profile and output factor measurements for the Exradin W1 plastic scintillation detector (PSD) for the Gamma Knife Perfexion (GKP) collimators in a Lucy phantom and to compare these values to an Exradin A16 ion chamber, EBT3 radiochromic film and treatment planning system (TPS) data. Methods: We used the Exradin W1 PSD which has a small volume, near-water equivalent sensitive element. It has also been shown to be energy independent. This new detector is manufactured and distributed by Standard Imaging, Inc. Measurements were performed for all three collimators (4 mm, 8 mm and 16 mm) for themore » GKP. The Lucy phantom with the PSD inserted was moved in small steps to acquire profiles in all three directions. EBT3 film was inserted in the Lucy phantom and exposed to a single shot for each collimator. Relative output factors were measured using the three detectors while profiles acquired with the PSD were compared to the ones measured with EBT3 radiochromic film. Results: Measured output factors relative to the largest collimator are as followsCollimator PS EBT3 A1616mm 1.000 1.000 1.0008mm 0.892 0.881 0.8834mm 0.795 0.793 0.727 The nominal (vendor) OFs for GKP are 1.000, 0.900, and 0.814, for collimators 16 mm, 8 mm and 4 mm, respectively. There is excellent agreement between all profiles measured with the PSD and EBT3 as well as with the TPS data provided by the vendor. Conclusion: Output factors measured with the W1 were consistent with the ones measured with EBT3 and A16 ion chamber. Measured profiles are in excellent agreement. The W1 detector seems well suited for beam QA for Gamma Knife due to its dosimetric characteristics. Sam Beddar would like to disclose a NIH/NCI SBIR Phase II grant (2R44CA153824-02A1) with Standard Imaging, Title: “Water-Equivalent Plastic Scintillation Detectors for Small Field Radiotherapy”.« less

  3. MO-D-213-05: Sensitivity of Routine IMRT QA Metrics to Couch and Collimator Rotations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alaei, P

    Purpose: To assess the sensitivity of gamma index and other IMRT QA metrics to couch and collimator rotations. Methods: Two brain IMRT plans with couch and/or collimator rotations in one or more of the fields were evaluated using the IBA MatriXX ion chamber array and its associated software (OmniPro-I’mRT). The plans were subjected to routine QA by 1) Creating a composite planar dose in the treatment planning system (TPS) with the couch/collimator rotations and 2) Creating the planar dose after “zeroing” the rotations. Plan deliveries to MatriXX were performed with all rotations set to zero on a Varian 21ex linearmore » accelerator. This in effect created TPS-created planar doses with an induced rotation error. Point dose measurements for the delivered plans were also performed in a solid water phantom. Results: The IMRT QA of the plans with couch and collimator rotations showed clear discrepancies in the planar dose and 2D dose profile overlays. The gamma analysis, however, did pass with the criteria of 3%/3mm (for 95% of the points), albeit with a lower percentage pass rate, when one or two of the fields had a rotation. Similar results were obtained with tighter criteria of 2%/2mm. Other QA metrics such as percentage difference or distance-to-agreement (DTA) histograms produced similar results. The point dose measurements did not obviously indicate the error due to location of dose measurement (on the central axis) and the size of the ion chamber used (0.6 cc). Conclusion: Relying on Gamma analysis, percentage difference, or DTA to determine the passing of an IMRT QA may miss critical errors in the plan delivery due to couch/collimator rotations. A combination of analyses for composite QA plans, or per-beam analysis, would detect these errors.« less

  4. SU-E-T-354: Efficient and Enhanced QA Testing of Linear Accelerators Using a Real-Time Beam Monitor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jung, J; Farrokhkish, M; Norrlinger, B

    2015-06-15

    Purpose: To investigate the feasibility of performing routine QA tests of linear accelerators (Linac) using the Integral Quality Monitoring (IQM) system. The system, consisting of a 1-D sensitivity gradient large area ion-chamber mounted at the collimator, allows automatic collection and analysis of beam data. Methods: The IQM was investigated to perform several QA constancy tests, similar to those recommended by AAPM TG142, of a Linac including: beam output, MLC calibration, beam symmetry, relative dose factor (RDF), dose linearity, output as a function of gantry angle and dose rate. All measurements by the IQM system accompanied a reference measurement using amore » conventional dosimetry system and were performed on an Elekta Infinity Linac with Agility MLC. The MLC calibration check is done using a Picket-Fence type 2×10cm{sup 2} field positioned at different off-axis locations along the chamber gradient. Beam symmetry constancy values are established by signals from an 4×4cm{sup 2} aperture located at various off-axis positions; the sensitivity of the test was determined by the changes in the signals in response to a tilt in the beam. The data for various square field sizes were used to develop a functional relationship with RDF. Results: The IQM tracked the beam output well within 1% of the reference ion-chamber readings. The Picket-Fence type field test detected a 1mm shift error of one MLC bank. The system was able to detect 2.5% or greater beam asymmetry. The IQM results for all other QA tests were found to agree with the reference values to within 0.5%. Conclusion: It was demonstrated that the IQM system can effectively monitor the Linac performance parameters for the purpose of routine QA constancy tests. With minimum user interactions a comprehensive set of tests can be performed efficiently, allowing frequent monitoring of the Linac. The presenting author’s salary is funded by the manufacturer of the QA device. All the other authors have financial interests with the commercialization of this QA device.« less

  5. SU-F-T-524: Investigation of the Dosimertric Benefits of Interchangeable Source Size of a Novel Rotating Gamma System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eldib, A; Chibani, O; Chen, L

    Purpose: Tremendous technological developments were made for conformal therapy techniques with linear accelerators, while less attention was paid to cobalt-60 units. The aim of the current study is to explore the dosimetric benefits of a novel rotating gamma ray system enhanced with interchangeable source sizes and multi-leaf collimator (MLC). Material and Methods: CybeRT is a novel rotating gamma ray machine with a ring gantry that ensures an iso-center accuracy of less than 0.3 mm. The new machine has a 70cm source axial distance allowing for improved penumbra compared to conventional machines. MCBEAM was used to simulate Cobalt-60 beams from themore » CybeRT head, while the MCPLAN code was used for modeling the MLC and for phantom/patient dose calculation. The CybeRT collimation will incorporate a system allowing for interchanging source sizes. In this work we have created phase space files for 1cm and 2cm source sizes. Evaluation of the system was done by comparing CybeRT beams with the 6MV beams in a water phantom and in patient geometry. Treatment plans were compared based on isodose distributions and dose volume histograms. Results: Profiles for the 1cm source were comparable to that from 6MV in the order of 6mm for 10×10 cm{sup 2} field size at the depth of maximum dose. This could ascribe to Cobalt-60 beams producing lowerenergy secondary electrons. Although, the 2cm source have a larger penumbra however it could be still used for large targets with proportionally increased dose rate. For large lung targets, the difference between cobalt and 6MV plans is clinically insignificant. Our preliminary results showed that interchanging source sizes will allow cobalt beams for volumetric arc therapy of both small lesions and large tumors. Conclusion: The CybeRT system will be a cost effective machine capable of performing advanced radiation therapy treatments of both small tumors and large target volumes.« less

  6. An image-guided precision proton radiation platform for preclinical in vivo research

    NASA Astrophysics Data System (ADS)

    Ford, E.; Emery, R.; Huff, D.; Narayanan, M.; Schwartz, J.; Cao, N.; Meyer, J.; Rengan, R.; Zeng, J.; Sandison, G.; Laramore, G.; Mayr, N.

    2017-01-01

    There are many unknowns in the radiobiology of proton beams and other particle beams. We describe the development and testing of an image-guided low-energy proton system optimized for radiobiological research applications. A 50 MeV proton beam from an existing cyclotron was modified to produce collimated beams (as small as 2 mm in diameter). Ionization chamber and radiochromic film measurements were performed and benchmarked with Monte Carlo simulations (TOPAS). The proton beam was aligned with a commercially-available CT image-guided x-ray irradiator device (SARRP, Xstrahl Inc.). To examine the alternative possibility of adapting a clinical proton therapy system, we performed Monte Carlo simulations of a range-shifted 100 MeV clinical beam. The proton beam exhibits a pristine Bragg Peak at a depth of 21 mm in water with a dose rate of 8.4 Gy min-1 (3 mm depth). The energy of the incident beam can be modulated to lower energies while preserving the Bragg peak. The LET was: 2.0 keV µm-1 (water surface), 16 keV µm-1 (Bragg peak), 27 keV µm-1 (10% peak dose). Alignment of the proton beam with the SARRP system isocenter was measured at 0.24 mm agreement. The width of the beam changes very little with depth. Monte Carlo-based calculations of dose using the CT image data set as input demonstrate in vivo use. Monte Carlo simulations of the modulated 100 MeV clinical proton beam show a significantly reduced Bragg peak. We demonstrate the feasibility of a proton beam integrated with a commercial x-ray image-guidance system for preclinical in vivo studies. To our knowledge this is the first description of an experimental image-guided proton beam for preclinical radiobiology research. It will enable in vivo investigations of radiobiological effects in proton beams.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Senaratne, Ruwan, E-mail: rsenarat@physics.ucsb.edu; Rajagopal, Shankari V.; Geiger, Zachary A.

    We present a simple and inexpensive design for a multichannel effusive oven nozzle which provides improved atomic beam collimation and thus extended oven lifetimes. Using this design, we demonstrate an atomic lithium source suitable for trapped-atom experiments. At a nozzle temperature of 525 °C, the collimated atomic beam flux directly after the nozzle is 1.2 × 10{sup 14} atoms/s with a peak beam intensity greater than 5.0 × 10{sup 16} atoms/s/sr. This suggests an oven lifetime of several decades of continuous operation.

  8. Ion source for high-precision mass spectrometry

    DOEpatents

    Todd, Peter J.; McKown, Henry S.; Smith, David H.

    1984-01-01

    The invention is directed to a method for increasing the precision of positive-ion relative abundance measurements conducted in a sector mass spectrometer having an ion source for directing a beam of positive ions onto a collimating slit. The method comprises incorporating in the source an electrostatic lens assembly for providing a positive-ion beam of circular cross section for collimation by the slit.

  9. Single-Pulse Multi-Point Multi-Component Interferometric Rayleigh Scattering Velocimeter

    NASA Technical Reports Server (NTRS)

    Bivolaru, Daniel; Danehy, Paul M.; Lee, Joseph W.; Gaffney, Richard L., Jr.; Cutler, Andrew D.

    2006-01-01

    A simultaneous multi-point, multi-component velocimeter using interferometric detection of the Doppler shift of Rayleigh, Mie, and Rayleigh-Brillouin scattered light in supersonic flow is described. The system uses up to three sets of collection optics and one beam combiner for the reference laser light to form a single collimated beam. The planar Fabry-Perot interferometer used in the imaging mode for frequency detection preserves the spatial distribution of the signal reasonably well. Single-pulse multi-points measurements of up to two orthogonal and one non-orthogonal components of velocity in a Mach 2 free jet were performed to demonstrate the technique. The average velocity measurements show a close agreement with the CFD calculations using the VULCAN code.

  10. X-ray luminescence computed tomography imaging based on X-ray distribution model and adaptively split Bregman method

    PubMed Central

    Chen, Dongmei; Zhu, Shouping; Cao, Xu; Zhao, Fengjun; Liang, Jimin

    2015-01-01

    X-ray luminescence computed tomography (XLCT) has become a promising imaging technology for biological application based on phosphor nanoparticles. There are mainly three kinds of XLCT imaging systems: pencil beam XLCT, narrow beam XLCT and cone beam XLCT. Narrow beam XLCT can be regarded as a balance between the pencil beam mode and the cone-beam mode in terms of imaging efficiency and image quality. The collimated X-ray beams are assumed to be parallel ones in the traditional narrow beam XLCT. However, we observe that the cone beam X-rays are collimated into X-ray beams with fan-shaped broadening instead of parallel ones in our prototype narrow beam XLCT. Hence we incorporate the distribution of the X-ray beams in the physical model and collected the optical data from only two perpendicular directions to further speed up the scanning time. Meanwhile we propose a depth related adaptive regularized split Bregman (DARSB) method in reconstruction. The simulation experiments show that the proposed physical model and method can achieve better results in the location error, dice coefficient, mean square error and the intensity error than the traditional split Bregman method and validate the feasibility of method. The phantom experiment can obtain the location error less than 1.1 mm and validate that the incorporation of fan-shaped X-ray beams in our model can achieve better results than the parallel X-rays. PMID:26203388

  11. Design and dosimetry characteristics of a commercial applicator system for intra-operative electron beam therapy utilizing ELEKTA Precise accelerator.

    PubMed

    Nevelsky, Alexander; Bernstein, Zvi; Bar-Deroma, Raquel; Kuten, Abraham; Orion, Itzhak

    2010-07-19

    The design concept and dosimetric characteristics of a new applicator system for intraoperative radiation therapy (IORT) are presented in this work. A new hard-docking commercial system includes polymethylmethacrylate (PMMA) applicators with different diameters and applicator end angles and a set of secondary lead collimators. A telescopic device allows changing of source-to-surface distance (SSD). All measurements were performed for 6, 9, 12 and 18 MeV electron energies. Output factors and percentage depth doses (PDD) were measured in a water phantom using a plane-parallel ion chamber. Isodose contours and radiation leakage were measured using a solid water phantom and radiographic films. The dependence of PDD on SSD was checked for the applicators with the smallest and the biggest diameters. SSD dependence of the output factors was measured. Hardcopies of PDD and isodose contours were prepared to help the team during the procedure on deciding applicator size and energy to be chosen. Applicator output factors are a function of energy, applicator size and applicator type. Dependence of SSD correction factors on applicator size and applicator type was found to be weak. The same SSD correction will be applied for all applicators in use for each energy. The radiation leakage through the applicators is clinically acceptable. The applicator system enables effective collimation of electron beams for IORT. The data presented are sufficient for applicator, energy and monitor unit selection for IORT treatment of a patient.

  12. Surface buildup dose dependence on photon field delivery technique for IMRT

    PubMed Central

    Yokoyama, Shigeru; Roberson, Peter L.; Litzenberg, Dale W.; Moran, Jean M.; Fraass, Benedick A.

    2004-01-01

    The more complex delivery techniques required for implementation of intensity‐modulated radiotherapy (IMRT) based on inverse planning optimization have changed the relationship between dose at depth and dose at buildup regions near the surface. Surface buildup dose is dependent on electron contamination primarily from the unblocked view of the flattening filter and secondarily from air and collimation systems. To evaluate the impact of beam segmentation on buildup dose, measurements were performed with 10×10 cm2 fields, which were delivered with 3 static 3.5×10 cm2 or 3×10 cm2 strips, 5 static 2×10 cm2 strips, 10 static 1×10 cm2 strips, and 1.1×10 cm2 dynamic delivery, compared with a 10×10 cm2 open field. Measurements were performed in water and Solid Water using parallel plate chambers, a stereotactic diode, and thermoluminescent dosimeters (TLDs) for a 6 MV X‐ray beam. Depth doses at 2 mm depth (relative to dose at 10 cm depth) were lower by 6%, 7%, 11%, and 10% for the above field delivery techniques, respectively, compared to the open field. These differences are most influenced by differences in multileaf collimator (MLC) transmission contributing to the useful beam. An example IMRT field was also studied to assess variations due to delivery technique (static vs. dynamic) and intensity level. Buildup dose is weakly dependent on the multileaf delivery technique for efficient IMRT fields. PACS numbers: 87.53.‐j, 87.53.Dq PMID:15738914

  13. Design of refractive laser beam shapers to generate complex irradiance profiles

    NASA Astrophysics Data System (ADS)

    Li, Meijie; Meuret, Youri; Duerr, Fabian; Vervaeke, Michael; Thienpont, Hugo

    2014-05-01

    A Gaussian laser beam is reshaped to have specific irradiance distributions in many applications in order to ensure optimal system performance. Refractive optics are commonly used for laser beam shaping. A refractive laser beam shaper is typically formed by either two plano-aspheric lenses or by one thick lens with two aspherical surfaces. Ray mapping is a general optical design technique to design refractive beam shapers based on geometric optics. This design technique in principle allows to generate any rotational-symmetric irradiance profile, yet in literature ray mapping is mainly developed to transform a Gaussian irradiance profile to a uniform profile. For more complex profiles especially with low intensity in the inner region, like a Dark Hollow Gaussian (DHG) irradiance profile, ray mapping technique is not directly applicable in practice. In order to these complex profiles, the numerical effort of calculating the aspherical surface points and fitting a surface with sufficient accuracy increases considerably. In this work we evaluate different sampling approaches and surface fitting methods. This allows us to propose and demonstrate a comprehensive numerical approach to efficiently design refractive laser beam shapers to generate rotational-symmetric collimated beams with a complex irradiance profile. Ray tracing analysis for several complex irradiance profiles demonstrates excellent performance of the designed lenses and the versatility of our design procedure.

  14. Hand held phase-shifting diffraction moire interferometer

    DOEpatents

    Deason, Vance A.; Ward, Michael B.

    1994-01-01

    An interferometer in which a coherent beam of light is generated within a remote case and transmitted to a hand held unit tethered to said remote case, said hand held unit having optical elements for directing a pair of mutually coherent collimated laser beams at a diffraction grating. Data from the secondary or diffracted beams are then transmitted to a separate video and data acquisition system for recording and analysis for load induced deformation or for identification purposes. Means are also provided for shifting the phase of one incident beam relative to the other incident beam and being controlled from within said remote case.

  15. WE-D-17A-01: A Dynamic Collimation System for Spot Scanned Proton Therapy: Conceptual Overview

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hyer, D; Hill, P; Wang, D

    2014-06-15

    Purpose: In the absence of a collimation system, the lateral penumbra in pencil beam scanning (PBS) proton therapy delivered at low energies is highly dependent on the spot size. This dependence, coupled with the fact that spot sizes increase with decreasing energy, reduces the benefit of the PBS technique for treating shallow tumors such as those found in the head and neck region. In order to overcome this limitation, a dynamic collimation system (DCS) was developed for sharpening the lateral penumbra of low energy proton therapy dose distributions delivered by PBS. Methods: The proposed DCS consists of two pairs ofmore » orthogonal trimmer blades which intercept the edges of the proton beam near the target edge in the beam's eye view. Each trimmer blade is capable of rapid motion in the direction perpendicular to the central beam axis by means of a linear motor, with maximum velocity and acceleration of 2.5 m/s and 19.6 m/s{sup 2}, respectively. Two-dimensional treatment plans were created both with and without the DCS for in-air spot sizes (σ-air) of 3, 5, 7, and 9 mm, representing a wide array of clinically available equipment. Results: In its current configuration, the snout of the DCS has outer dimensions of 22.6 × 22.6 cm{sup 2} and is capable of delivering a minimum treatment field size of 15 × 15 cm{sup 2}. Using off the shelf components, the constructed system would weigh less than 20 kg. The treatment plans created with the DCS yielded a reduction in the mean dose to normal tissue surrounding the target of 26.2–40.6% for spot sizes of 3–9 mm, respectively. Conclusion: The DCS can be integrated with current or future proton therapy equipment and we believe it will serve as a useful tool to further improve the next generation of proton therapy delivery.« less

  16. Application of Gaussian beam ray-equivalent model and back-propagation artificial neural network in laser diode fast axis collimator assembly.

    PubMed

    Yu, Hao; Rossi, Giammarco; Braglia, Andrea; Perrone, Guido

    2016-08-10

    The paper presents the development of a tool based on a back-propagation artificial neural network to assist in the accurate positioning of the lenses used to collimate the beam from semiconductor laser diodes along the so-called fast axis. After training using a Gaussian beam ray-equivalent model, the network is capable of indicating the tilt, decenter, and defocus of such lenses from the measured field distribution, so the operator can determine the errors with respect to the actual lens position and optimize the diode assembly procedure. An experimental validation using a typical configuration exploited in multi-emitter diode module assembly and fast axis collimating lenses with different focal lengths and numerical apertures is reported.

  17. Comparison of secondary neutron dose in proton therapy resulting from the use of a tungsten alloy MLC or a brass collimator system.

    PubMed

    Diffenderfer, Eric S; Ainsley, Christopher G; Kirk, Maura L; McDonough, James E; Maughan, Richard L

    2011-11-01

    To apply the dual ionization chamber method for mixed radiation fields to an accurate comparison of the secondary neutron dose arising from the use of a tungsten alloy multileaf collimator (MLC) as opposed to a brass collimator system for defining the shape of a therapeutic proton field. Hydrogenous and nonhydrogenous ionization chambers were constructed with large volumes to enable measurements of absorbed doses below 10(-4) Gy in mixed radiation fields using the dual ionization chamber method for mixed-field dosimetry. Neutron dose measurements were made with a nominal 230 MeV proton beam incident on a closed tungsten alloy MLC and a solid brass block. The chambers were cross-calibrated against a (60)Co-calibrated Farmer chamber in water using a 6 MV x-ray beam and Monte Carlo simulations were performed to account for variations in ionization chamber response due to differences in secondary neutron energy spectra. The neutron and combined proton plus γ-ray absorbed doses are shown to be nearly equivalent downstream from either a closed tungsten alloy MLC or a solid brass block. At 10 cm downstream from the distal edge of the collimating material the neutron dose from the closed MLC was (5.3 ± 0.4) × 10(- 5) Gy/Gy. The neutron dose with brass was (6.4 ± 0.7) × 10(- 5) Gy/Gy. Further from the secondary neutron source, at 50 cm, the neutron doses remain close for both the MLC and brass block at (6.9 ± 0.6) × 10(- 6) Gy/Gy and (6.3 ± 0.7) × 10(- 6) Gy/Gy, respectively. The dual ionization chamber method is suitable for measuring secondary neutron doses resulting from proton irradiation. The results of measurements downstream from a closed tungsten alloy MLC and a brass block indicate that, even in an overly pessimistic worst-case scenario, secondary neutron production in a tungsten alloy MLC leads to absorbed doses that are nearly equivalent to those seen from brass collimators. Therefore, the choice of tungsten alloy in constructing the leaves of a proton MLC is appropriate, and does not lead to a substantial increase in the secondary neutron dose to the patient compared to that generated in a brass collimator.

  18. Visualization of fluid turbulence and acoustic cavitation during phacoemulsification.

    PubMed

    Tognetto, Daniele; Sanguinetti, Giorgia; Sirotti, Paolo; Brezar, Edoardo; Ravalico, Giuseppe

    2005-02-01

    To describe a technique for visualizing fluid turbulence and cavitational energy created by ultrasonic phaco tips. University Eye Clinic of Trieste, Trieste, Italy. Generation of cavitational energy by the phaco tip was visualized using an optical test bench comprising several components. The technique uses a telescope system to expand a laser light source into a coherent, collimated beam of light with a diameter of approximately 50.0 mm. The expanded laser beam shines on the test tube containing the tip activated in a medium of water or ophthalmic viscosurgical device (OVD). Two precision optical collimators complete the optical test bench and form the system used to focus data onto a charge-coupled device television camera connected to a recorder. Images of irrigation, irrigation combined with aspiration, irrigation/aspiration, and phacosonication were obtained with the tip immersed in a tube containing water or OVD. Optical image processing enabled acoustic cavitation to be visualized during phacosonication. The system is a possible means of evaluating a single phaco apparatus power setting and comparing phaco machines and techniques.

  19. High-Sensitivity Microwave Optics.

    ERIC Educational Resources Information Center

    Nunn, W. M., Jr.

    1981-01-01

    Describes a 3.33-cm wavelength (9 GHz) microwave system that achieves a high overall signal sensitivity and a well-collimated beam with moderate-size equipment. The system has been used to develop microwave versions of the Michelson interferometer, Bragg reflector, Brewster's law and total internal reflection, and Young's interference experiment.…

  20. WE-EF-BRA-06: Feasibility of Spatially Modulated Proton Beams for Small Animal Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, E; Meyer, J

    Purpose: To investigate the feasibility of proton minibeam radiotherapy (pMBRT) for small animal research. The motivation is to explore with protons the extraordinary normal tissue sparing effects to spatially modulated beams as observed on high flux synchrotron beam lines. We hypothesized that we can design a multi-slit collimator for our proton beam line to produce planar-parallel dose profiles with high modulation in the entrance region and homogenous dose coverage in the overlap of the Bragg peaks. Methods: The high dose rate 50 MeV research proton beamline at the University of Washington was modeled using the TOol for PArticle Simulation (TOPAS)more » Monte Carlo package. A brass collimator was implemented to generate proton minibeams. The collimator consists of an array of 2 cm long slits to cover an area of 2×2 cm{sup 2}. The slit widths (0.1–1 mm), center-to-center (ctc) distances (1–3 mm) and collimator thickness (1–7 cm) were varied to evaluate the effect on dose rate, the peak-to-valley dose ratios (PVDR) and the change of penumbra and peak width (FWHM) with depth. Results: The Bragg peak was at a depth of ∼21 mm. The penumbra and FWHM remained relatively constant to a depth of about 10–15 mm. The PVDR ranged from 1.6 to 26 and the dose rate dropped exponentially with collimator thickness. A uniform dose can be achieved at depth with slightly compromised PVDRs and dose rate. Conclusion: The technical realization of pMBRT is feasible. The simulations have shown that it is possible to obtain uniform dose at depth while modulation is maintained on the entrance side. While the simulated beam widths are larger than on synchrotron generated microbeams the dosimetric advantage could avoid having to interlace two microbeams to achieve uniform dose in the target. The next steps are to build a collimator and verify the simulations experimentally.« less

  1. 2.1 μm high-power laser diode beam combining(Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Berrou, Antoine P. C.; Elder, Ian F.; Lamb, Robert A.; Esser, M. J. Daniel

    2016-10-01

    Laser power and brightness scaling, in "eye safe" atmospheric transmission windows, is driving laser system research and development. High power lasers with good beam quality, at wavelength around 2.1 µm, are necessary for optical countermeasure applications. For such applications, focusing on efficiency and compactness of the system is mandatory. In order to cope with these requirements, one must consider the use of laser diodes which emit directly in the desired spectral region. The challenge for these diodes is to maintain a good beam quality factor as the output power increases. 2 µm diodes with excellent beam quality in both axes are available with output powers of 100 mW. Therefore, in order to reach multi-watt of average output power, broad-area single emitters and beam combining becomes relevant. Different solutions have been implemented in the 1.9 to 2 µm wavelength range, one of which is to stack multiple emitter bars reaching more than one hundred watt, while another is a fibre coupled diode module. The beam propagation factor of these systems is too high for long atmospheric propagation applications. Here we describe preliminary results on non-coherent beam combining of 2.1 µm high power Fabry-Perot GaSb laser diodes supplied by Brolis Semiconductors Ltd. First we evaluated single mode diodes (143 mW) with good beam quality (M2 < 1.5 for slow axis and < 1.1 for fast axis). Then we characterized broad-area single emitter diodes (808 mW) with an electrical-to-optical efficiency of 19 %. The emitter width was 90 µm with a cavity length of 1.5 mm. In our experiments we found that the slow axis multimode output beam consisted of two symmetric lobes with a total full width at half maximum (FWHM) divergence angle of 25 degrees, corresponding to a calculated beam quality factor of M2 = 25. The fast axis divergence was specified to be 44 degrees, with an expected beam quality factor close to the diffraction limit, which informed our selection of collimation lenses used in the experiment. We evaluated two broadband (1.8 - 3 µm) AR coated Geltech aspheric lenses with focal lengths of 1.87 mm and 4 mm, with numerical apertures of 0.85 and 0.56, respectively, as an initial collimation lens, followed by an additional cylindrical lens of focal length 100 mm for fully collimating the slow axis. Using D-shaped gold-coated mirrors, multiple single emitter beams are stacked in the fast axis direction with the objective that the combined beam has a beam propagation factor in the stacking direction close to the beam propagation factor of the slow axis of a single emitter, e.g. M2 of 20 to 25 in both axes. We further found that the output beam of a single emitter is highly linearly polarized along the slow axis, making it feasible to implement polarization beam combining techniques to increase the beam power by a factor two while maintaining the same beam quality. Along with full beam characterization, a power scaling strategy towards a multi-watt output power beam combining laser system will be presented.

  2. Ion source for high-precision mass spectrometry

    DOEpatents

    Todd, P.J.; McKown, H.S.; Smith, D.H.

    1982-04-26

    The invention is directed to a method for increasing the precision of positive-ion relative abundance measurements conducted in a sector mass spectrometer having an ion source for directing a beam of positive ions onto a collimating slit. The method comprises incorporating in the source an electrostatic lens assembly for providing a positive-ion beam of circular cross section for collimation by the slit. 2 figures, 3 tables.

  3. Optical development system lab alignment solutions for the ICESat-2 ATLAS instrument

    NASA Astrophysics Data System (ADS)

    Evans, T.

    The ATLAS Instrument for the ICESat-2 mission at NASA's Goddard Space Flight Center requires an alignment test-bed to prove out new concepts. The Optical Development System (ODS) lab was created to test prototype models of individual instrument components to simulate how they will act as a system. The main ICESat-2 instrument is the Advanced Topographic Laser Altimeter System (ATLAS). It measures ice elevation by transmitting laser pulses, and collecting the reflection in a telescope. Because the round trip time is used to calculate distance, alignment between the outgoing transmitter beam and the incoming receiver beams are critical. An automated closed loop monitoring control system is currently being tested at the prototype level to prove out implementation for the final spacecraft. To achieve an error of less than 2 micro-radians, an active deformable mirror was used to correct the lab wave front from the collimated “ ground reflection” beam. The lab includes a focal plane assembly set up, a one meter diameter collimator optic, and a 0.8 meter flight spare telescope for alignment. ATLAS prototypes and engineering models of transmitter and receiver optics and sub-systems are brought in to develop and integrate systems as well as write procedures to be used in integration and testing. By having a fully integrated system with prototypes and engineering units, lessons can be learned before flight designs are finalized.

  4. SU-F-T-481: Physics Evaluation of a Newly Released InCise™ Multileaf Collimator for CyberKnife M6™ System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, L; Chin, E; Lo, A

    2016-06-15

    Purpose: This work reports the results of the physics evaluation of a newly released InCise™2 Multileaf Collimator (MLC) installed in our institution. Methods: Beam property data was measured with unshielded diode and EBT2 films. The measurements included MLC leaf transmission, beam profiles, output factors and tissue-phantom ratios. MLC performance was evaluated for one month after commissioning. Weekly Garden Fence tests were performed for leaf / bank positioning in standard (A/P) and clinically relevant non-standard positions, before and after MLC driving exercises of 10+ minutes. Daily Picket Fence test and AQA test, End-to-End tests and dosimetric quality assurance were performed tomore » evaluate the overall system performance. Results: All measurements including beam energy, flatness and symmetry, were within manufacture specifications. Leaf transmission was 0.4% <0.5% specification. The values of output factors ranged from 0.825 (7.6 mm × 7.5 mm) to 1.026 (115.0 mm × 100.1 mm). Average beam penumbra at 10 cm depth ranged from 2.7mm/2.7mm(7.6 mm × 7.5 mm) to 6.0 mm/6.2mm(84.6 mm × 84.7 mm). Slight penumbra difference (<10% from average penumbra for fields >20 mm) was observed in the direction perpendicular to leaf motion due to the tilting of the leaf housing. Mean leaf position offsets was −0.08±0.07mm and −0.13 ± 0.08 for X1 and X2 leaf banks in 13 Garden Fence tests. No significant difference on average leaf positioning offsets was observed between different leaf orientations and before/after MLC driving exercises. Six End-to-End tests showed 0.43±0.23mm overall targeting accuracy. Picket-Fence and AQA showed stable performance of MLC during the test period. Dosimetric point dose measurements for test cases agreed with calculation within 3%. All film measurements on relative dose had Gamma (2%, 2mm) passing rate of >95%. Conclusion: The Incise™2 MLC for CyberKnife M6™ was proven to be accurate and reliable, and it is currently in clinical use. Stanford was one of the physics evaluation sites for the newly released InCise 2 MLC for Accuray Inc.« less

  5. A coherent light scanner for optical processing of large format transparencies

    NASA Technical Reports Server (NTRS)

    Callen, W. R.; Weaver, J. E.; Shackelford, R. G.; Walsh, J. R.

    1975-01-01

    A laser scanner is discussed in which the scanning beam is random-access addressable and perpendicular to the image input plane and the irradiance of the scanned beam is controlled so that a constant average irradiance is maintained after passage through the image plane. The scanner's optical system and design are described, and its performance is evaluated. It is noted that with this scanner, data in the form of large-format transparencies can be processed without the expense, space, maintenance, and precautions attendant to the operation of a high-power laser with large-aperture collimating optics. It is shown that the scanned format as well as the diameter of the scanning beam may be increased by simple design modifications and that higher scan rates can be achieved at the expense of resolution by employing acousto-optic deflectors with different relay optics.

  6. Radiation shielding of the Fermilab 16 GeV proton driver

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nikolai V. Mokhov, Alexander I. Drozhdin and Oleg E. Krivosheev

    2001-07-12

    The radiation transport analysis in the proposed Fermi-lab 1.2 MWProton Driver (PD) [1] is fundamentally important because of the impact on machine performance, conventional facility design, maintenance operations, and related costs. The strategy adopted in the PD design is that the beam losses in the machine are localized and controlled as much as possible via the dedicated beam collimation system, with a high loss rate localized in that section and drastically lower uncontrolled beam loss rate in the rest of the lattice. Results of thorough Monte Carlo calculations of prompt and residual radiation in and around the PD components aremore » presented for realistic assumptions and geometry under normal operation and accidental conditions. This allowed one to conduct shielding design and analysis to meet regulatory requirements [2] for external shielding, hands-on maintenance and ground-water activation.« less

  7. The propagation of a flattened circular Gaussian beam through an optical system in turbulent atmosphere

    NASA Astrophysics Data System (ADS)

    Chu, X. X.; Liu, Z. J.; Wu, Y.

    2008-07-01

    Based on the Huygens-Fresnel integral, the properties of a circular flattened Gaussian beam through a stigmatic optical system in turbulent atmosphere are investigated. Analytical formulas for the average intensity are derived. As elementary examples, the average intensity distributions of a collimated circular flattened Gaussian beam and a focused circular flattened Gaussian beam through a simple optical system are studied. To see the effects of the optical system on the propagation, the average intensity distributions of the beam for direct propagation are also studied. From the analysis, comparison and numerical calculation we can see that there are many differences between the two propagations. These differences are due to the geometrical magnification of the optical system, different diffraction and different turbulence-induced spreading. Namely, an optical system not only affects the diffraction but also affects the turbulence-induced spreading.

  8. System analysis of wavelength beam combining of high-power diode lasers for photoacoustic endoscopy

    NASA Astrophysics Data System (ADS)

    Leggio, Luca; Gallego, Daniel C.; Gawali, Sandeep B.; Sánchez, Miguel; Rodriguez, Sergio; Osiński, Marek; Sacher, Joachim; Carpintero, Guillermo; Lamela, Horacio

    2016-04-01

    This paper, originally published on 27 April 2016, was replaced with a corrected/revised version on 8 June 2016. If you downloaded the original PDF but are unable to access the revision, please contact SPIE Digital Library Customer Service for assistance. The purpose of wavelength-beam combining (WBC) is to improve the output power of a multi-wavelength laser system while maintaining the quality of the combined beam. This technique has been primarily proposed for industrial applications, such as metal cutting and soldering, which require optical peak power between kilowatts and megawatts. In order to replace the bulkier solid-state lasers, we propose to use the WBC technique for photoacoustic (PA) applications, where a multi-wavelength focused beam with optical peak power between hundreds of watts up to several kilowatts is necessary to penetrate deeply into biological tissues. In this work we present an analytical study about the coupling of light beams emitted by diode laser bars at 808 nm, 880 nm, 910 nm, 940 nm, and 980 nm into a < 600-μm core-diameter optical fiber for PA endoscopy. In order to achieve an efficient coupling it is necessary to collimate the beams in both fast and slow axes by means of cylindrical lenses and to use partial reflection mirrors at 45° tilt. We show an example of beam collimation using cylindrical lenses in both fast and slow axes. In a real PA scenario, the resulting beam should have a sufficient peak power to generate significant PA signals from a turbid tissue>.

  9. X-ray luminescence computed tomography using a focused x-ray beam.

    PubMed

    Zhang, Wei; Lun, Michael C; Nguyen, Alex Anh-Tu; Li, Changqing

    2017-11-01

    Due to the low x-ray photon utilization efficiency and low measurement sensitivity of the electron multiplying charge coupled device camera setup, the collimator-based narrow beam x-ray luminescence computed tomography (XLCT) usually requires a long measurement time. We, for the first time, report a focused x-ray beam-based XLCT imaging system with measurements by a single optical fiber bundle and a photomultiplier tube (PMT). An x-ray tube with a polycapillary lens was used to generate a focused x-ray beam whose x-ray photon density is 1200 times larger than a collimated x-ray beam. An optical fiber bundle was employed to collect and deliver the emitted photons on the phantom surface to the PMT. The total measurement time was reduced to 12.5 min. For numerical simulations of both single and six fiber bundle cases, we were able to reconstruct six targets successfully. For the phantom experiment, two targets with an edge-to-edge distance of 0.4 mm and a center-to-center distance of 0.8 mm were successfully reconstructed by the measurement setup with a single fiber bundle and a PMT. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

  10. Evaluation of dual γ-ray imager with active collimator using various types of scintillators.

    PubMed

    Lee, Wonho; Lee, Taewoong; Jeong, Manhee; Kim, Ho Kyung

    2011-10-01

    The performance of a specialized dual γ-ray imager using both mechanical and electronic collimation was evaluated by Monte Carlo simulation (MCNP5). The dual imager consisted of an active collimator and a planar detector that were made from scintillators. The active collimator served not only as a coded aperture for mechanical collimation but also as a first detector for electronic collimation. Therefore, a single system contained both mechanical and electronic collimation. Various types of scintillators were tested and compared with each other in terms of their angular resolution, efficiency, and background noise. In general, a BGO active collimator had the best mechanical collimation performance, and an LaCl₃(Ce) active collimator provided the best electronic collimation performance. However, for low radiation energies, the mechanical collimation images made from both scintillators showed the same quality, and, for high radiation energies, electronic collimation images made from both scintillators also show similar quality. Therefore, if mechanical collimation is used to detect low-energy radiation and electronic collimation is applied to reconstruct a high-energy source, either LaCl₃(Ce) or BGO would be appropriate for the active collimator of a dual γ-ray imager. These results broaden the choice of scintillators for the active collimator of the dual γ-ray imager, which makes it possible to consider other factors, such as machinability and cost, in making the imager. As a planar detector, BGO showed better performance than other scintillators since its radiation detection efficiency was highest of all. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Design of a setup for 252Cf neutron source for storage and analysis purpose

    NASA Astrophysics Data System (ADS)

    Hei, Daqian; Zhuang, Haocheng; Jia, Wenbao; Cheng, Can; Jiang, Zhou; Wang, Hongtao; Chen, Da

    2016-11-01

    252Cf is a reliable isotopic neutron source and widely used in the prompt gamma ray neutron activation analysis (PGNAA) technique. A cylindrical barrel made by polymethyl methacrylate contained with the boric acid solution was designed for storage and application of a 5 μg 252Cf neutron source. The size of the setup was optimized with Monte Carlo code. The experiments were performed and the results showed the doses were reduced with the setup and less than the allowable limit. The intensity and collimating radius of the neutron beam could also be adjusted through different collimator.

  12. SU-F-T-671: Effects of Collimator Material On Proton Minibeams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, E; Sandison, G; Cao, N

    2016-06-15

    Purpose: To investigate the dosimetric effects of collimator material on spatially modulated proton minibeams (pMBRT). Methods: pMBRT holds promise to exhibit shallow depth normal-tissue sparing effects similar to synchrotron based microbeams while also retaining potential for uniform dose distributions for tumor targets. TOPAS Monte Carlo simulations were performed for a 5cm thick multislit collimator with 0.3mm slits and 1mm center-to-center spacing for a 50.5MeV proton minibeam while varying collimator material between brass, tungsten, and iron. The collimator was placed both “flush” at the water phantom surface and at 5cm distance to investigate the effects on surface dose, peak-to-valley-dose-ratio (PVDR) andmore » neutron contribution. Results: For flush placement, the neutron dose at the phantom surface for the tungsten collimator was approximately 20% higher than for brass and iron. This was not reflected in the overall surface dose, which was comparable for all materials due to the relatively low neutron contribution of <0.1%. When the collimator was retracted, the overall neutron contribution was essentially identical for all three collimators. Surface dose dropped by ∼40% for all collimator materials with air gap compared to being flush with the phantom surface. This surface dose reduction was at the cost of increase in valley dose for all collimator materials due to increased angular divergence of the mini-beams at the surface and their consequent geometric penumbra at depth. When the collimator was placed at distance from the phantom surface the PVDR decreased. The peak-to-entrance-dose ratio was highest for the iron collimator with 5cm air gap. Conclusion: The dosimetric difference between the collimator materials is minimal despite the relatively higher neutron contribution at the phantom surface for the tungsten collimator when placed flush. The air gap between the collimator and phantom surface strongly influences all dosimetry parameters due to the influence of scatter on the narrow spatial modulation.« less

  13. Minimal-effort planning of active alignment processes for beam-shaping optics

    NASA Astrophysics Data System (ADS)

    Haag, Sebastian; Schranner, Matthias; Müller, Tobias; Zontar, Daniel; Schlette, Christian; Losch, Daniel; Brecher, Christian; Roßmann, Jürgen

    2015-03-01

    In science and industry, the alignment of beam-shaping optics is usually a manual procedure. Many industrial applications utilizing beam-shaping optical systems require more scalable production solutions and therefore effort has been invested in research regarding the automation of optics assembly. In previous works, the authors and other researchers have proven the feasibility of automated alignment of beam-shaping optics such as collimation lenses or homogenization optics. Nevertheless, the planning efforts as well as additional knowledge from the fields of automation and control required for such alignment processes are immense. This paper presents a novel approach of planning active alignment processes of beam-shaping optics with the focus of minimizing the planning efforts for active alignment. The approach utilizes optical simulation and the genetic programming paradigm from computer science for automatically extracting features from a simulated data basis with a high correlation coefficient regarding the individual degrees of freedom of alignment. The strategy is capable of finding active alignment strategies that can be executed by an automated assembly system. The paper presents a tool making the algorithm available to end-users and it discusses the results of planning the active alignment of the well-known assembly of a fast-axis collimator. The paper concludes with an outlook on the transferability to other use cases such as application specific intensity distributions which will benefit from reduced planning efforts.

  14. The practical Pomeron for high energy proton collimation

    NASA Astrophysics Data System (ADS)

    Appleby, R. B.; Barlow, R. J.; Molson, J. G.; Serluca, M.; Toader, A.

    2016-10-01

    We present a model which describes proton scattering data from ISR to Tevatron energies, and which can be applied to collimation in high energy accelerators, such as the LHC and FCC. Collimators remove beam halo particles, so that they do not impinge on vulnerable regions of the machine, such as the superconducting magnets and the experimental areas. In simulating the effect of the collimator jaws it is crucial to model the scattering of protons at small momentum transfer t, as these protons can subsequently survive several turns of the ring before being lost. At high energies these soft processes are well described by Pomeron exchange models. We study the behaviour of elastic and single-diffractive dissociation cross sections over a wide range of energy, and show that the model can be used as a global description of the wide variety of high energy elastic and diffractive data presently available. In particular it models low mass diffraction dissociation, where a rich resonance structure is present, and thus predicts the differential and integrated cross sections in the kinematical range appropriate to the LHC. We incorporate the physics of this model into the beam tracking code MERLIN and use it to simulate the resulting loss maps of the beam halo lost in the collimators in the LHC.

  15. Characteristic of laser diode beam propagation through a collimating lens.

    PubMed

    Xu, Qiang; Han, Yiping; Cui, Zhiwei

    2010-01-20

    A mathematical model of a laser diode beam propagating through a collimating lens is presented. Wave propagation beyond the paraxial approximation is studied. The phase delay of the laser diode wave in passing through the lens is analyzed in detail. The propagation optical field after the lens is obtained from the diffraction integral by the stationary phase method. The model is employed to predict the light intensity at various beam cross sections, and the computed intensity distributions are in a good agreement with the corresponding measurements.

  16. Tomotherapy as a tool in image-guided radiation therapy (IGRT): theoretical and technological aspects

    PubMed Central

    Yartsev, S; Kron, T; Van Dyk, J

    2007-01-01

    Helical tomotherapy (HT) is a novel treatment approach that combines Intensity-Modulate Radiation Therapy (IMRT) delivery with in-built image guidance using megavoltage (MV) CT scanning. The technique utilises a 6 MV linear accelerator mounted on a CT type ring gantry. The beam is collimated to a fan beam, which is intensity modulated using a binary multileaf collimator (MLC). As the patient advances slowly through the ring gantry, the linac rotates around the patient with a leaf-opening pattern optimised to deliver a highly conformal dose distribution to the target in the helical beam trajectory. The unit also allows the acquisition of MVCT images using the same radiation source detuned to reduce its effective energy to 3.5 MV, making the dose required for imaging less than 3 cGy. This paper discusses the major features of HT and describes the advantages and disadvantages of this approach in the context of the commercial Hi-ART system. PMID:21614257

  17. Creating and Steering Highly Directional Electron Beams in Graphene.

    PubMed

    Liu, Ming-Hao; Gorini, Cosimo; Richter, Klaus

    2017-02-10

    We put forward a concept to create highly collimated, nondispersive electron beams in pseudorelativistic Dirac materials such as graphene or topological insulator surfaces. Combining negative refraction and Klein collimation at a parabolic pn junction, the proposed lens generates beams, as narrow as the focal length, that stay focused over scales of several microns and can be steered by a magnetic field without losing collimation. We demonstrate the lens capabilities by applying it to two paradigmatic settings of graphene electron optics: We propose a setup for observing high-resolution angle-dependent Klein tunneling, and, exploiting the intimate quantum-to-classical correspondence of these focused electron waves, we consider high-fidelity transverse magnetic focusing accompanied by simulations for current mapping through scanning gate microscopy. Our proposal opens up new perspectives for next-generation graphene electron optics experiments.

  18. Creating and Steering Highly Directional Electron Beams in Graphene

    NASA Astrophysics Data System (ADS)

    Liu, Ming-Hao; Gorini, Cosimo; Richter, Klaus

    2017-02-01

    We put forward a concept to create highly collimated, nondispersive electron beams in pseudorelativistic Dirac materials such as graphene or topological insulator surfaces. Combining negative refraction and Klein collimation at a parabolic p n junction, the proposed lens generates beams, as narrow as the focal length, that stay focused over scales of several microns and can be steered by a magnetic field without losing collimation. We demonstrate the lens capabilities by applying it to two paradigmatic settings of graphene electron optics: We propose a setup for observing high-resolution angle-dependent Klein tunneling, and, exploiting the intimate quantum-to-classical correspondence of these focused electron waves, we consider high-fidelity transverse magnetic focusing accompanied by simulations for current mapping through scanning gate microscopy. Our proposal opens up new perspectives for next-generation graphene electron optics experiments.

  19. Water-cooled hard-soldered kilowatt laser diode arrays operating at high duty cycle

    NASA Astrophysics Data System (ADS)

    Klumel, Genady; Karni, Yoram; Oppenhaim, Jacob; Berk, Yuri; Shamay, Moshe; Tessler, Renana; Cohen, Shalom; Risemberg, Shlomo

    2010-04-01

    High brightness laser diode arrays are increasingly found in defense applications either as efficient optical pumps or as direct energy sources. In many instances, duty cycles of 10- 20 % are required, together with precise optical collimation. System requirements are not always compatible with the use of microchannel based cooling, notwithstanding their remarkable efficiency. Simpler but effective solutions, which will not involve high fluid pressure drops as well as deionized water, are needed. The designer is faced with a number of challenges: effective heat removal, minimization of the built- in and operational stresses as well as precise and accurate fast axis collimation. In this article, we report on a novel laser diode array which includes an integral tap water cooling system. Robustness is achieved by all around hard solder bonding of passivated 940nm laser bars. Far field mapping of the beam, after accurate fast axis collimation will be presented. It will be shown that the design of water cooling channels , proper selection of package materials, careful design of fatigue sensitive parts and active collimation technique allow for long life time and reliability, while not compromising the laser diode array efficiency, optical power density ,brightness and compactness. Main performance characteristics are 150W/bar peak optical power, 10% duty cycle and more than 50% wall plug efficiency with less than 1° fast axis divergence. Lifetime of 0.5 Gshots with less than 10% power degradation has been proved. Additionally, the devices have successfully survived harsh environmental conditions such as thermal cycling of the coolant temperature and mechanical shocks.

  20. Comparison of penumbra regions produced by ancient Gamma knife model C and Gamma ART 6000 using Monte Carlo MCNP6 simulation.

    PubMed

    Banaee, Nooshin; Asgari, Sepideh; Nedaie, Hassan Ali

    2018-07-01

    The accuracy of penumbral measurements in radiotherapy is pivotal because dose planning computers require accurate data to adequately modeling the beams, which in turn are used to calculate patient dose distributions. Gamma knife is a non-invasive intracranial technique based on principles of the Leksell stereotactic system for open deep brain surgeries, invented and developed by Professor Lars Leksell. The aim of this study is to compare the penumbra widths of Leksell Gamma Knife model C and Gamma ART 6000. Initially, the structure of both systems were simulated by using Monte Carlo MCNP6 code and after validating the accuracy of simulation, beam profiles of different collimators were plotted. MCNP6 beam profile calculations showed that the penumbra values of Leksell Gamma knife model C and Gamma ART 6000 for 18, 14, 8 and 4 mm collimators are 9.7, 7.9, 4.3, 2.6 and 8.2, 6.9, 3.6, 2.4, respectively. The results of this study showed that since Gamma ART 6000 has larger solid angle in comparison with Gamma Knife model C, it produces better beam profile penumbras than Gamma Knife model C in the direct plane. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Initial experimental evidence of self-collimation of target-normal-sheath-accelerated proton beam in a stack of conducting foils

    NASA Astrophysics Data System (ADS)

    Ni, P. A.; Lund, S. M.; McGuffey, C.; Alexander, N.; Aurand, B.; Barnard, J. J.; Beg, F. N.; Bellei, C.; Bieniosek, F. M.; Brabetz, C.; Cohen, R. H.; Kim, J.; Neumayer, P.; Roth, M.; Logan, B. G.

    2013-08-01

    Phenomena consistent with self-collimation (or weak self-focusing) of laser target-normal-sheath-accelerated protons was experimentally observed for the first time, in a specially engineered structure ("lens") consisting of a stack of 300 thin aluminum foils separated by 50 μm vacuum gaps. The experiments were carried out in a "passive environment," i.e., no external fields applied, neutralization plasma or injection of secondary charged particles was imposed. Experiments were performed at the petawatt "PHELIX" laser user facility (E = 100 J, Δt = 400 fs, λ = 1062 nm) at the "Helmholtzzentrum für Schwerionenforschung-GSI" in Darmstadt, Germany. The observed rms beam spot reduction depends inversely on energy, with a focusing degree decreasing monotonically from 2 at 5.4 MeV to 1.5 at 18.7 MeV. The physics inside the lens is complex, resulting in a number of different mechanisms that can potentially affect the particle dynamics within the structure. We present a plausible simple interpretation of the experiment in which the combination of magnetic self-pinch forces generated by the beam current together with the simultaneous reduction of the repulsive electrostatic forces due to the foils are the dominant mechanisms responsible for the observed focusing/collimation. This focusing technique could be applied to a wide variety of space-charge dominated proton and heavy ion beams and impact fields and applications, such as HEDP science, inertial confinement fusion in both fast ignition and heavy ion fusion approaches, compact laser-driven injectors for a Linear Accelerator (LINAC) or synchrotron, medical therapy, materials processing, etc.

  2. Initial experimental evidence of self-collimation of TNSA proton beam in a stack of conducting foils

    NASA Astrophysics Data System (ADS)

    Ni, Pavel

    2013-10-01

    Phenomena consistent with self-collimation (or weak self-focusing) of laser target-normal-sheath-accelerated (TNSA) protons was experimentally observed for the first time, in a specially engineered structure (``lens'') consisting of a stack of 300 thin aluminum foils separated by 50 μm vacuum gaps. The experiments were carried out in a ``passive environment,'' i.e. no external fields applied, neutralization plasma or injection of secondary charged particles was imposed. Experiments were performed at the petawatt ``PHELIX'' laser user facility (E = 100 J, Δt = 400 fs, λ = 1062 nm) at the ``Helmholtzzentrum für Schwerionenforschung-GSI'' in Darmstadt, Germany. The observed rms beam spot reduction depends inversely on energy, with a focusing degree decreasing monotonically from 2 at 5.4 MeV to 1.5 MeV at 18.7 MeV. The physics inside the lens is complex, resulting in a number of different mechanisms that can potentially affect the particle dynamics within the structure. We present a plausible simple interpretation of the experiment in which the combination of magnetic self-pinch forces generated by the beam current together with the simultaneous reduction of the repulsive electrostatic forces due to the foils are the dominant mechanisms responsible for the observed focusing/collimation. This focusing technique could be applied to a wide variety of space-charge dominated proton and heavy ion beams and impact fields and applications, such as HEDP science, inertial confinement fusion in both fast ignition and heavy ion fusion approaches, compact laser-driven injectors for a LINAC or synchrotron, medical therapy, materials processing, etc.

  3. Design of optimal collimation for dedicated molecular breast imaging systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weinmann, Amanda L.; Hruska, Carrie B.; O'Connor, Michael K.

    2009-03-15

    Molecular breast imaging (MBI) is a functional imaging technique that uses specialized small field-of-view gamma cameras to detect the preferential uptake of a radiotracer in breast lesions. MBI has potential to be a useful adjunct method to screening mammography for the detection of occult breast cancer. However, a current limitation of MBI is the high radiation dose (a factor of 7-10 times that of screening mammography) associated with current technology. The purpose of this study was to optimize the gamma camera collimation with the aim of improving sensitivity while retaining adequate resolution for the detection of sub-10-mm lesions. Square-hole collimatorsmore » with holes matched to the pixilated cadmium zinc telluride detector elements of the MBI system were designed. Data from MBI patient studies and parameters of existing dual-head MBI systems were used to guide the range of desired collimator resolutions, source-to-collimator distances, pixel sizes, and collimator materials that were examined. General equations describing collimator performance for a conventional gamma camera were used in the design process along with several important adjustments to account for the specialized imaging geometry of the MBI system. Both theoretical calculations and a Monte Carlo model were used to measure the geometric efficiency (or sensitivity) and resolution of each designed collimator. Results showed that through optimal collimation, collimator sensitivity could be improved by factors of 1.5-3.2, while maintaining a collimator resolution of either {<=}5 or {<=}7.5 mm at a distance of 3 cm from the collimator face. These gains in collimator sensitivity permit an inversely proportional drop in the required dose to perform MBI.« less

  4. An MCNP-based model of a medical linear accelerator x-ray photon beam.

    PubMed

    Ajaj, F A; Ghassal, N M

    2003-09-01

    The major components in the x-ray photon beam path of the treatment head of the VARIAN Clinac 2300 EX medical linear accelerator were modeled and simulated using the Monte Carlo N-Particle radiation transport computer code (MCNP). Simulated components include x-ray target, primary conical collimator, x-ray beam flattening filter and secondary collimators. X-ray photon energy spectra and angular distributions were calculated using the model. The x-ray beam emerging from the secondary collimators were scored by considering the total x-ray spectra from the target as the source of x-rays at the target position. The depth dose distribution and dose profiles at different depths and field sizes have been calculated at a nominal operating potential of 6 MV and found to be within acceptable limits. It is concluded that accurate specification of the component dimensions, composition and nominal accelerating potential gives a good assessment of the x-ray energy spectra.

  5. Near-field collimation of light carrying orbital angular momentum with bull's-eye-assisted plasmonic coaxial waveguides.

    PubMed

    Pu, Mingbo; Ma, Xiaoliang; Zhao, Zeyu; Li, Xiong; Wang, Yanqin; Gao, Hui; Hu, Chenggang; Gao, Ping; Wang, Changtao; Luo, Xiangang

    2015-07-10

    The orbital angular momentum (OAM) of light, as an emerging hotspot in optics and photonics, introduces many degrees of freedom for applications ranging from optical communication and quantum processing to micromanipulation. To achieve a high degree of integration, optical circuits for OAM light are essential, which are, however, challenging in the optical regime owing to the lack of well-developed theory. Here we provide a scheme to guide and collimate the OAM beam at the micro- and nano-levels. The coaxial plasmonic slit was exploited as a naturally occurring waveguide for light carrying OAM. Concentric grooves etched on the output surface of the coaxial waveguide were utilized as a plasmonic metasurface to couple the OAM beam to free space with greatly increased beam directivity. Experimental results at λ = 532 nm validated the novel transportation and collimating effect of the OAM beam. Furthermore, dynamic tuning of the topological charges was demonstrated by using a liquid crystal spatial light modulator (SLM).

  6. Near-field collimation of light carrying orbital angular momentum with bull’s-eye-assisted plasmonic coaxial waveguides

    NASA Astrophysics Data System (ADS)

    Pu, Mingbo; Ma, Xiaoliang; Zhao, Zeyu; Li, Xiong; Wang, Yanqin; Gao, Hui; Hu, Chenggang; Gao, Ping; Wang, Changtao; Luo, Xiangang

    2015-07-01

    The orbital angular momentum (OAM) of light, as an emerging hotspot in optics and photonics, introduces many degrees of freedom for applications ranging from optical communication and quantum processing to micromanipulation. To achieve a high degree of integration, optical circuits for OAM light are essential, which are, however, challenging in the optical regime owing to the lack of well-developed theory. Here we provide a scheme to guide and collimate the OAM beam at the micro- and nano-levels. The coaxial plasmonic slit was exploited as a naturally occurring waveguide for light carrying OAM. Concentric grooves etched on the output surface of the coaxial waveguide were utilized as a plasmonic metasurface to couple the OAM beam to free space with greatly increased beam directivity. Experimental results at λ = 532 nm validated the novel transportation and collimating effect of the OAM beam. Furthermore, dynamic tuning of the topological charges was demonstrated by using a liquid crystal spatial light modulator (SLM).

  7. Near-field collimation of light carrying orbital angular momentum with bull’s-eye-assisted plasmonic coaxial waveguides

    PubMed Central

    Pu, Mingbo; Ma, Xiaoliang; Zhao, Zeyu; Li, Xiong; Wang, Yanqin; Gao, Hui; Hu, Chenggang; Gao, Ping; Wang, Changtao; Luo, Xiangang

    2015-01-01

    The orbital angular momentum (OAM) of light, as an emerging hotspot in optics and photonics, introduces many degrees of freedom for applications ranging from optical communication and quantum processing to micromanipulation. To achieve a high degree of integration, optical circuits for OAM light are essential, which are, however, challenging in the optical regime owing to the lack of well-developed theory. Here we provide a scheme to guide and collimate the OAM beam at the micro- and nano-levels. The coaxial plasmonic slit was exploited as a naturally occurring waveguide for light carrying OAM. Concentric grooves etched on the output surface of the coaxial waveguide were utilized as a plasmonic metasurface to couple the OAM beam to free space with greatly increased beam directivity. Experimental results at λ = 532 nm validated the novel transportation and collimating effect of the OAM beam. Furthermore, dynamic tuning of the topological charges was demonstrated by using a liquid crystal spatial light modulator (SLM). PMID:26159423

  8. Coherent beam combining of collimated fiber array based on target-in-the-loop technique

    NASA Astrophysics Data System (ADS)

    Li, Xinyang; Geng, Chao; Zhang, Xiaojun; Rao, Changhui

    2011-11-01

    Coherent beam combining (CBC) of fiber array is a promising way to generate high power and high quality laser beams. Target-in-the-loop (TIL) technique might be an effective way to ensure atmosphere propagation compensation without wavefront sensors. In this paper, we present very recent research work about CBC of collimated fiber array using TIL technique at the Key Lab on Adaptive Optics (KLAO), CAS. A novel Adaptive Fiber Optics Collimator (AFOC) composed of phase-locking module and tip/tilt control module was developed. CBC experimental setup of three-element fiber array was established. Feedback control is realized using stochastic parallel gradient descent (SPGD) algorithm. The CBC based on TIL with piston and tip/tilt correction simultaneously is demonstrated. And the beam pointing to locate or sweep position of combined spot on target was achieved through TIL technique too. The goal of our work is achieve multi-element CBC for long-distance transmission in atmosphere.

  9. Practical UAV Optical Sensor Bench with Minimal Adjustability

    NASA Technical Reports Server (NTRS)

    Pilgrim, Jeffrey; Gonzales, Paula

    2013-01-01

    A multiple-pass optical platform eliminates essentially all optical alignment degrees of freedom, save one. A four-pass absorption spectrometer architecture is made rigid by firmly mounting dielectric-coated mirror prisms with no alignment capability to the platform. The laser diode beam is collimated by a small, custom-developed lens, which has only a rotational degree of freedom along the standard optical "z" axis. This degree is itself eliminated by adhesive after laser collimation. Only one degree of freedom is preserved by allowing the laser diode chip and mount subassembly to move relative to the collimating lens by using over-sized mounting holes. This allows full 360 deg motion of a few millimeters relative to the lens, which, due to the high numerical aperture of the lens, provides wide directional steering of the collimated laser beam.

  10. A 62-MeV Proton Beam for the Treatment of Ocular Melanoma at Laboratori Nazionali del Sud-INFN

    NASA Astrophysics Data System (ADS)

    Cirrone, G. A. P.; Cuttone, G.; Lojacono, P. A.; Lo Nigro, S.; Mongelli, V.; Patti, I. V.; Privitera, G.; Raffaele, L.; Rifuggiato, D.; Sabini, M. G.; Salamone, V.; Spatola, C.; Valastro, L. M.

    2004-06-01

    At the Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali del Sud (INFN-LNS) in Catania, Italy, the first Italian protontherapy facility, named Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) has been built in collaboration with the University of Catania. It is based on the use of the 62-MeV proton beam delivered by the K=800 Superconducting Cyclotron installed and working at INFN-LNS since 1995. The facility is mainly devoted to the treatment of ocular diseases like uveal melanoma. A beam treatment line in air has been assembled together with a dedicated positioning patient system. The facility has been in operation since the beginning of 2002 and 66 patients have been successfully treated up to now. The main features of CATANA together with the clinical and dosimetric features will be extensively described; particularly, the proton beam line, that has been entirely built at LNS, with all its elements, the experimental transversal and depth dose distributions of the 62-MeV proton beam obtained for a final collimator of 25-mm diameter and the experimental depth dose distributions of a modulated proton beam obtained for the same final collimator. Finally, the clinical results over 1 yr of treatments, describing the features of the treated diseases will be reported.

  11. Beam shaping optics to enhance performance of interferometry techniques in grating manufacture

    NASA Astrophysics Data System (ADS)

    Laskin, Alexander; Laskin, Vadim; Ostrun, Aleksei

    2018-02-01

    Improving of industrial holographic and interferometry techniques is of great importance in interference lithography, computer-generated holography, holographic data storage, interferometry recording of Bragg gratings as well as gratings of various types in semiconductor industry. Performance of mentioned techniques is essentially enhanced by providing a light beam with flat phase front and flat-top irradiance distribution. Therefore, transformation of Gaussian distribution of a TEM00 laser to flat-top (top hat, uniform) distribution is an important optical task. There are different refractive and diffractive beam shaping approaches used in laser industrial and scientific applications, but only few of them are capable to fulfil the optimum conditions for beam quality demanding holography and interferometry. As a solution it is suggested to apply refractive field mapping beam shaping optics πShaper, which operational principle presumes almost lossless transformation of Gaussian to flat-top beam with flatness of output wavefront, conserving of beam consistency, providing collimated low divergent output beam, high transmittance, extended depth of field, negligible wave aberration, and achromatic design provides capability to work with several lasers with different wavelengths simultaneously. High optical quality of resulting flat-top beam allows applying additional optical components to build various imaging optical systems for variation of beam size and shape to fulfil requirements of a particular application. This paper will describe design basics of refractive beam shapers and optical layouts of their applying in holography and laser interference lithography. Examples of real implementations and experimental results will be presented as well.

  12. Controllability in Multi-Stage Laser Ion Acceleration

    NASA Astrophysics Data System (ADS)

    Kawata, S.; Kamiyama, D.; Ohtake, Y.; Barada, D.; Ma, Y. Y.; Kong, Q.; Wang, P. X.; Gu, Y. J.; Li, X. F.; Yu, Q.

    2015-11-01

    The present paper shows a concept for a future laser ion accelerator, which should have an ion source, ion collimators, ion beam bunchers and ion post acceleration devices. Based on the laser ion accelerator components, the ion particle energy and the ion energy spectrum are controlled, and a future compact laser ion accelerator would be designed for ion cancer therapy or for ion material treatment. In this study each component is designed to control the ion beam quality. The energy efficiency from the laser to ions is improved by using a solid target with a fine sub-wavelength structure or a near-critical density gas plasma. The ion beam collimation is performed by holes behind the solid target or a multi-layered solid target. The control of the ion energy spectrum and the ion particle energy, and the ion beam bunching are successfully realized by a multi-stage laser-target interaction. A combination of each component provides a high controllability of the ion beam quality to meet variable requirements in various purposes in the laser ion accelerator. The work was partly supported by MEXT, JSPS, ASHULA project/ ILE, Osaka University, CORE (Center for Optical Research and Education, Utsunomiya University, Japan), Fudan University and CDI (Creative Dept. for Innovation) in CCRD, Utsunomiya University.

  13. Hand held phase-shifting diffraction Moire interferometer

    DOEpatents

    Deason, V.A.; Ward, M.B.

    1994-09-20

    An interferometer is described in which a coherent beam of light is generated within a remote case and transmitted to a hand held unit tethered to said remote case, said hand held unit having optical elements for directing a pair of mutually coherent collimated laser beams at a diffraction grating. Data from the secondary or diffracted beams are then transmitted to a separate video and data acquisition system for recording and analysis for load induced deformation or for identification purposes. Means are also provided for shifting the phase of one incident beam relative to the other incident beam and being controlled from within said remote case. 4 figs.

  14. Automated collimation testing by determining the statistical correlation coefficient of Talbot self-images.

    PubMed

    Rana, Santosh; Dhanotia, Jitendra; Bhatia, Vimal; Prakash, Shashi

    2018-04-01

    In this paper, we propose a simple, fast, and accurate technique for detection of collimation position of an optical beam using the self-imaging phenomenon and correlation analysis. Herrera-Fernandez et al. [J. Opt.18, 075608 (2016)JOOPDB0150-536X10.1088/2040-8978/18/7/075608] proposed an experimental arrangement for collimation testing by comparing the period of two different self-images produced by a single diffraction grating. Following their approach, we propose a testing procedure based on correlation coefficient (CC) for efficient detection of variation in the size and fringe width of the Talbot self-images and thereby the collimation position. When the beam is collimated, the physical properties of the self-images of the grating, such as its size and fringe width, do not vary from one Talbot plane to the other and are identical; the CC is maximum in such a situation. For the de-collimated position, the size and fringe width of the self-images vary, and correspondingly the CC decreases. Hence, the magnitude of CC is a measure of degree of collimation. Using the method, we could set the collimation position to a resolution of 1 μm, which relates to ±0.25   μ    radians in terms of collimation angle (for testing a collimating lens of diameter 46 mm and focal length 300 mm). In contrast to most collimation techniques reported to date, the proposed technique does not require a translation/rotation of the grating, use of complicated phase evaluation algorithms, or an intricate method for determination of period of the grating or its self-images. The technique is fully automated and provides high resolution and precision.

  15. Evaluation of clinically applied treatment beams with respect to bunker shielding parameters for a Cyberknife M6.

    PubMed

    Henzen, Dominik; Schmidhalter, Daniel; Zanella, Claudia Christina; Volken, Werner; Mackeprang, Paul-Henry; Malthaner, Marco; Fix, Michael Karl; Manser, Peter

    2018-01-01

    Compared to a conventional linear accelerator, the Cyberknife (CK) is a unique system with respect to radiation protection shielding and the variety and number of non-coplanar beams are two key components regarding this aspect. In this work, a framework to assess the direction distribution and modulation factor (MF) of clinically applied treatment beams of a CyberKnife M6 is developed. Database filtering options allow studying the influence of different parameters such as collimator types, treatment sites or different bunker sizes. A distribution of monitor units (MU) is generated by projecting treatment beams onto the walls, floor and ceiling of the CyberKnife bunker. This distribution is found to be highly heterogeneous and depending, among other parameters, on the bunker size. For our bunker design, 10%-13% of the MUs are delivered to the right and left wall, each. The floor receives more than 64% of the applied MUs, while the wall behind the patient's head is not hit by primary treatment beams. Between 0% and 5% of the total MUs are delivered to the wall at the patient's feet. This number highly depends on the treatment site, e.g., for extracranial patients no beams hit that wall. Collimator choice was found to have minor influence on the distribution of MUs. On the other hand, the MF depends on the collimator type as well as on the treatment site. The MFs (delivered MU/prescribed dose) for all treatments, all MLC treatments, cranial and extracranial treatments are 8.3, 6.4, 7.7, and 9.9 MU/cGy, respectively. The developed framework allows assessing and monitoring important parameters regarding radiation protection of a CK-M6 using the actually applied treatment beams. Furthermore, it enables evaluating different clinical and constructional situations using the filtering options. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

  16. High-performance continuous-wave room temperature 4.0-μm quantum cascade lasers with single-facet optical emission exceeding 2 W

    PubMed Central

    Lyakh, A.; Maulini, R.; Tsekoun, A.; Go, R.; Von der Porten, S.; Pflügl, C.; Diehl, L.; Capasso, Federico; Patel, C. Kumar N.

    2010-01-01

    A strain-balanced, AlInAs/InGaAs/InP quantum cascade laser structure, designed for light emission at 4.0 μm using nonresonant extraction design approach, was grown by molecular beam epitaxy. Laser devices were processed in buried heterostructure geometry. An air-cooled laser system incorporating a 10-mm × 11.5-μm laser with antireflection-coated front facet and high-reflection-coated back facet delivered over 2 W of single-ended optical power in a collimated beam. Maximum continuous-wave room temperature wall plug efficiency of 5.0% was demonstrated for a high-reflection-coated 3.65-mm × 8.7-μm laser mounted on an aluminum nitride submount.

  17. Design of laser afocal zoom expander system

    NASA Astrophysics Data System (ADS)

    Jiang, Lian; Zeng, Chun-Mei; Hu, Tian-Tian

    2018-01-01

    Laser afocal zoom expander system due to the beam diameter variable, can be used in the light sheet illumination microscope to observe the samples of different sizes. Based on the principle of afocal zoom system, the laser collimation and beam expander system with a total length of less than 110mm, 6 pieces of spherical lens and a beam expander ratio of 10 is designed by using Zemax software. The system is focused on laser with a wavelength of 532nm, divergence angle of less than 4mrad and incident diameter of 4mm. With the combination of 6 spherical lens, the beam divergence angle is 0.4mrad at the maximum magnification ratio, and the RMS values at different rates are less than λ/4. This design is simple in structure and easy to process and adjust. It has certain practical value.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harker, Y.D.

    On August 3-4, 1994, an INEL team made measurements related to a real-time monitoring system for use on the epithermal beam facility at the BMRR. BNL has installed two fission chambers in front of the beam collimator, which are to monitor the beam coming from the reactor. These two monitors are located with one just above the 16-cm dia. front aperture and the other is just below. The fission chambers contain depleted uranium, but because of the small amount of U-235 present, they respond to thermal and near thermal neutrons rather than fast neutrons. This feature combined with their relativelymore » small size (0.6 cm dia x 4 cm long) makes them very good monitors in the BMRR epithermal neutron beam. The INEL team worked with H.B. Lui (BNL) in performing initial tests of these monitors and established the settings to achieve stable operation. The main purpose of the measurement studies was to establish a basis for a monitoring method that tracks the dose the patient is receiving rather than the neutron fluence being delivered down the beam line.« less

  19. Method and apparatus for determining the physical properties of materials using dynamic light scattering techniques

    NASA Technical Reports Server (NTRS)

    Dhadwal, Harbans S. (Inventor)

    1992-01-01

    A system for determining the physical properties of materials through the use of dynamic light scattering is disclosed. The system includes a probe, a laser source for directing a laser beam into the probe, and a photodetector for converting scattered light detected by the probe into electrical signals. The probe includes at least one optical fiber connected to the laser source and a second optical fiber connected to the photodetector. Each of the fibers may adjoin a gradient index microlens which is capable of providing a collimated laser beam into a scattering medium. The position of the second optical fiber with respect to the optical axis of the probe determines whether homodyne or self-beating detection is provided. Self-beating detection may be provided without a gradient index microlens. This allows a very small probe to be constructed which is insertable through a hypodermic needle or the like into a droplet extending from such a needle. A method of detecting scattered light through the use of a collimated, Gaussian laser beam is also provided. A method for controlling the waist and divergence of the optical field emanating from the free end of an optical fiber is also provided.

  20. Equipment and Tracking Test Results for the NRL Ship-to- Ship DF Laser Transmission Experiment.

    DTIC Science & Technology

    1982-04-05

    combined with the 2" collimated HeNe laser beam at dichoric beam splitter TBSI. TF2, TF1 , and TPFI direct the beam onto the f/6 parabola Pl. From...following work was done on the pumping system: 1. Install new valves , springs, and seats. 2. Install a new drive shaft, with new bearings and seals. 3...Install a new needle valve in the oil regulator. 4. Steam clean the inside pump surface. The new components were tested first with F2 fuel, then with NF 3

  1. A study of optical design and optimization of laser optics

    NASA Astrophysics Data System (ADS)

    Tsai, C.-M.; Fang, Yi-Chin

    2013-09-01

    This paper propose a study of optical design of laser beam shaping optics with aspheric surface and application of genetic algorithm (GA) to find the optimal results. Nd: YAG 355 waveband laser flat-top optical system, this study employed the Light tools LDS (least damped square) and the GA of artificial intelligence optimization method to determine the optimal aspheric coefficient and obtain the optimal solution. This study applied the aspheric lens with GA for the flattening of laser beams using collimated laser beam light, aspheric lenses in order to achieve best results.

  2. Light beam shaping for collimated emission from white organic light-emitting diodes using customized lenticular microlens arrays structure

    NASA Astrophysics Data System (ADS)

    Zhou, Lei; Bai, Gui-Lin; Guo, Xin; Shen, Su; Ou, Qing-Dong; Fan, Yuan-Yuan

    2018-05-01

    We present a design approach to realizing a desired collimated planar incoherent light source (CPILS) by incorporating lenticular microlens arrays (LMLAs) onto the substrates of discrete white organic light-emitting diode (WOLED) light sources and demonstrate the effectiveness of this method in collimated light beam shaping and luminance enhancement simultaneously. The obtained collimated WOLED light source shows enhanced luminance by a factor of 2.7 compared with that of the flat conventional device at the normal polar angle and, more importantly, exhibits a narrowed angular emission with a full-width at half-maximum (FWHM) of ˜33.6°. We anticipate that the presented strategy could provide an alternative way for achieving the desired large scale CPILS, thereby opening the door to many potential applications, including LCD backlights, three-dimensional displays, car headlights, and so forth.

  3. SU-F-T-178: Optimized Design of a Diamond Detector Specifically Dedicated to the Dose Distribution Measurements in Clinical Proton Pencil Beams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moignier, C; Pomorski, M; Agelou, M

    2016-06-15

    Purpose: In proton-therapy, pencil beam scanning (PBS) dosimetry presents a real challenge due to the small size of the beam (about 3 to 8 mm in FWHM), the pulsed high dose rate (up to 100 Gy/s) and the proton energy variation (about 30 MeV to 250 MeV). In the framework of French INSERM DEDIPRO project, a specifically dedicated single crystal diamond dosimeter (SCDDo) was developed with the objective of obtaining accurate measurements of the dose distribution in PBS modality. Methods: Monte Carlo simulations with MCNPX were performed. A small proton beam of 5 mm in FWHM was simulated as wellmore » as diamond devices with various size, thickness and holder composition. The calculated doses-to-diamond were compared with the doses-to-water in order to reduce the perturbation effects. Monte-Carlo simulations lead to an optimized SCDDo design for small proton beams dosimetry. Following the optimized design, SCDDos were mounted in water-equivalent holders with electrical connection adapted to standard electrometer. First, SCDDos performances (stability, repeatability, signal-to-background ratio…) were evaluated with conventional photon beams. Then, characterizations (dose linearity, dose rate dependence…) with wide proton beams were performed at proton-therapy center (IC-CPO) from Curie Institute (France) with the passive proton delivery technique, in order to confirm dosimetric requirements. Finally, depth-dose distributions were measured in a water tank, for native and modulated Bragg Peaks with the collimator of 12 cm, and compared to a commercial PPC05 parallel-plate ionization chamber reference detector. Lateral-dose profiles were also measured with the collimator of 5 mm, and compared to a commercial SFD diode. Results: The results show that SCDDo design does not disturb the dose distributions. Conclusion: The experimental dose distributions with the SCDDo are in good agreement with the commercial detectors and no energy dependence was observed with this device configuration.« less

  4. Initial alignment method for free space optics laser beam

    NASA Astrophysics Data System (ADS)

    Shimada, Yuta; Tashiro, Yuki; Izumi, Kiyotaka; Yoshida, Koichi; Tsujimura, Takeshi

    2016-08-01

    The authors have newly proposed and constructed an active free space optics transmission system. It is equipped with a motor driven laser emitting mechanism and positioning photodiodes, and it transmits a collimated thin laser beam and accurately steers the laser beam direction. It is necessary to introduce the laser beam within sensible range of the receiver in advance of laser beam tracking control. This paper studies an estimation method of laser reaching point for initial laser beam alignment. Distributed photodiodes detect laser luminescence at respective position, and the optical axis of laser beam is analytically presumed based on the Gaussian beam optics. Computer simulation evaluates the accuracy of the proposed estimation methods, and results disclose that the methods help us to guide the laser beam to a distant receiver.

  5. SU-G-IeP3-07: High-Resolution, High-Sensitivity Imaging and Quantification of Intratumoral Distributions of Gold Nanoparticles Using a Benchtop L-Shell XRF Imaging System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manohar, N; Diagaradjane, P; Krishnan, S

    2016-06-15

    Purpose: To demonstrate the ability to perform high-resolution imaging and quantification of sparse distributions of gold nanoparticles (GNPs) within ex vivo tumor samples using a highly-sensitive benchtop L-shell x-ray fluorescence (XRF) imaging system. Methods: An optimized L-shell XRF imaging system was assembled using a tungsten-target x-ray source (operated at 62 kVp and 45 mA). The x-rays were filtered (copper: 0.08 mm & aluminum: 0.04 mm) and collimated (lead: 5 cm thickness, 3 cm aperture diameter) into a cone-beam in order to irradiate small samples or objects. A collimated (stainless steel: 4 cm thickness, 2 mm aperture diameter) silicon drift detector,more » capable of 2D translation, was placed at 90° with respect to the beam to acquire XRF/scatter spectra from regions of interest. Spectral processing involved extracting XRF signal from background, followed by attenuation correction using a Compton scatter-based normalization algorithm. Calibration phantoms with water/GNPs (0 and 0.00001–10 mg/cm{sup 3}) were used to determine the detection limit of the system at a 10-second acquisition time. The system was then used to map the distribution of GNPs within a 12×11×2 mm{sup 3} slice excised from the center of a GNP-loaded ex vivo murine tumor sample; a total of 110 voxels (2.65×10{sup −3} cm{sup 3}) were imaged with 1.3-mm spatial resolution. Results: The detection limit of the current cone-beam benchtop L-shell XRF system was 0.003 mg/cm{sup 3} (3 ppm). Intratumoral GNP concentrations ranging from 0.003 mg/cm{sup 3} (3 ppm) to a maximum of 0.055 mg/cm{sup 3} (55 ppm) and average of 0.0093 mg/cm{sup 3} (9.3 ppm) were imaged successfully within the ex vivo tumor slice. Conclusion: The developed cone-beam benchtop L-shell XRF imaging system can immediately be used for imaging of ex vivo tumor samples containing low concentrations of GNPs. With minor finetuning/optimization, the system can be directly adapted for performing routine preclinical in vivo imaging tasks. Supported by NIH/NCI grant R01CA155446 This investigation was supported by NIH/NCI grant R01CA155446.« less

  6. Very High Reflectivity Supermirrors And Their Applications

    NASA Astrophysics Data System (ADS)

    Mezei, F.

    1989-01-01

    Very high reflectivity (some 95 % or better) supermirrors, with cut-off angles up to 2 times the critical angle of Ni coated simple total reflection neutron mirrors, can be produced using well established conventional deposition techniques. This performance makes applications involving multiple reflections and transmission geometries feasible, which in turn allow us to use more sophisticated neutron optical systems in order to optimize performance and minimize the amount a scarce supermirrors required. A key feature of several of these novel systems is the distribution of tasks between the several optical components achieving the desired performance by multiple action. The design and characteristics of a series of novel applications, such as polarizing cavities, collimators and guides, non-polarizing guides, beam compressors, deflectors and splitters (most of them tested or being implemented) are the main subjects of the present paper.

  7. SparseCT: interrupted-beam acquisition and sparse reconstruction for radiation dose reduction

    NASA Astrophysics Data System (ADS)

    Koesters, Thomas; Knoll, Florian; Sodickson, Aaron; Sodickson, Daniel K.; Otazo, Ricardo

    2017-03-01

    State-of-the-art low-dose CT methods reduce the x-ray tube current and use iterative reconstruction methods to denoise the resulting images. However, due to compromises between denoising and image quality, only moderate dose reductions up to 30-40% are accepted in clinical practice. An alternative approach is to reduce the number of x-ray projections and use compressed sensing to reconstruct the full-tube-current undersampled data. This idea was recognized in the early days of compressed sensing and proposals for CT dose reduction appeared soon afterwards. However, no practical means of undersampling has yet been demonstrated in the challenging environment of a rapidly rotating CT gantry. In this work, we propose a moving multislit collimator as a practical incoherent undersampling scheme for compressed sensing CT and evaluate its application for radiation dose reduction. The proposed collimator is composed of narrow slits and moves linearly along the slice dimension (z), to interrupt the incident beam in different slices for each x-ray tube angle (θ). The reduced projection dataset is then reconstructed using a sparse approach, where 3D image gradients are employed to enforce sparsity. The effects of the collimator slits on the beam profile were measured and represented as a continuous slice profile. SparseCT was tested using retrospective undersampling and compared against commercial current-reduction techniques on phantoms and in vivo studies. Initial results suggest that SparseCT may enable higher performance than current-reduction, particularly for high dose reduction factors.

  8. Planar microlens with front-face angle: design, fabrication, and characterization

    NASA Astrophysics Data System (ADS)

    Al Hafiz, Md. Abdullah; Michael, Aron; Kwok, Chee-Yee

    2016-07-01

    This paper studies the effect of microlens front-face angle on the performance of an optical system consisting of a planar-graded refractive index (GRIN) lens pair facing each other separated by a free-space region. The planar silica microlens pairs are designed to facilitate low-loss optical signal propagation in the free-space region between the opposing optical waveguides. The planar lens is fabricated from a 38-μm-thick fluorine-doped silica layer on a silicon substrate. It has a parabolic refractive index profile in the vertical direction, which is achieved by controlled fluorine incorporation in the silica film to collimate the optical beam in the vertical direction. Horizontal beam collimation is achieved by incorporating a horizontal curvature at the front face of the lens defined by deep oxide etch. A generalized 3×3 ABCDGH transformation matrix method has been derived to compute the coupling efficiency of such microlens pairs to take front-face angles that may be present due to fabrication variations or limitations and possible input/output optical fiber offset/tilt into considerations. Pairs of such planar GRIN lens with various free-space propagation distances between them ranging from 75 to 2500 μm and with front-face angles of 1.5 deg, 2 deg, and 4 deg have been fabricated and characterized. Beam propagation method simulations have been carried out to substantiate the theoretical and experimental results. The results indicate that the optical loss is reasonably low up to 1.5 deg of front-face angles and increases significantly with further increase in the front-face angle. Analysis shows that for a given system with specific microlens front-face angle, the optical loss can be significantly reduced by properly compensating the vertical position of the input and output fibers.

  9. Radiation environment simulations at the Tevatron, studies of the beam profile and measurement of the B c meson mass

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nicolas, Ludovic Y.

    2005-09-01

    The description of a computer simulation of the CDF detector at Fermilab and the adjacent accelerator parts is detailed, with MARS calculations of the radiation background in various elements of the model due to the collision of beams and machine-related losses. Three components of beam halo formation are simulated for the determination of the principal source of radiation background in CDF due to beam losses. The effect of a collimator as a protection for the detector is studied. The simulation results are compared with data taken by a CDF group. Studies of a 150 GeV Tevatron proton beam are performedmore » to investigate the transverse diffusion growth and distribution. A technique of collimator scan is used to scrape the beam under various experimental conditions, and computer programs are written for the beam reconstruction. An average beam halo growth speed is given and the potential of beam tail reconstruction using the collimator scan is evaluated. A particle physics analysis is conducted in order to detect the B c → J/Ψπ decay signal with the CDF Run II detector in 360 pb -1 of data. The cut variables and an optimization method to determine their values are presented along with a criterion for the detection threshold of the signal. The mass of the B{sub c} meson is measured with an evaluation of the significance of the signal.« less

  10. Monte Carlo study for designing a dedicated “D”-shaped collimator used in the external beam radiotherapy of retinoblastoma patients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mayorga, P. A.; Departamento de Física Atómica, Molecular y Nuclear, Universidad de Granada, E-18071 Granada; Brualla, L.

    2014-01-15

    Purpose: Retinoblastoma is the most common intraocular malignancy in the early childhood. Patients treated with external beam radiotherapy respond very well to the treatment. However, owing to the genotype of children suffering hereditary retinoblastoma, the risk of secondary radio-induced malignancies is high. The University Hospital of Essen has successfully treated these patients on a daily basis during nearly 30 years using a dedicated “D”-shaped collimator. The use of this collimator that delivers a highly conformed small radiation field, gives very good results in the control of the primary tumor as well as in preserving visual function, while it avoids themore » devastating side effects of deformation of midface bones. The purpose of the present paper is to propose a modified version of the “D”-shaped collimator that reduces even further the irradiation field with the scope to reduce as well the risk of radio-induced secondary malignancies. Concurrently, the new dedicated “D”-shaped collimator must be easier to build and at the same time produces dose distributions that only differ on the field size with respect to the dose distributions obtained by the current collimator in use. The scope of the former requirement is to facilitate the employment of the authors' irradiation technique both at the authors' and at other hospitals. The fulfillment of the latter allows the authors to continue using the clinical experience gained in more than 30 years. Methods: The Monte Carlo codePENELOPE was used to study the effect that the different structural elements of the dedicated “D”-shaped collimator have on the absorbed dose distribution. To perform this study, the radiation transport through a Varian Clinac 2100 C/D operating at 6 MV was simulated in order to tally phase-space files which were then used as radiation sources to simulate the considered collimators and the subsequent dose distributions. With the knowledge gained in that study, a new, simpler, “D”-shaped collimator is proposed. Results: The proposed collimator delivers a dose distribution which is 2.4 cm wide along the inferior-superior direction of the eyeball. This width is 0.3 cm narrower than that of the dose distribution obtained with the collimator currently in clinical use. The other relevant characteristics of the dose distribution obtained with the new collimator, namely, depth doses at clinically relevant positions, penumbrae width, and shape of the lateral profiles, are statistically compatible with the results obtained for the collimator currently in use. Conclusions: The smaller field size delivered by the proposed collimator still fully covers the planning target volume with at least 95% of the maximum dose at a depth of 2 cm and provides a safety margin of 0.2 cm, so ensuring an adequate treatment while reducing the irradiated volume.« less

  11. A dose optimization method for electron radiotherapy using randomized aperture beams

    NASA Astrophysics Data System (ADS)

    Engel, Konrad; Gauer, Tobias

    2009-09-01

    The present paper describes the entire optimization process of creating a radiotherapy treatment plan for advanced electron irradiation. Special emphasis is devoted to the selection of beam incidence angles and beam energies as well as to the choice of appropriate subfields generated by a refined version of intensity segmentation and a novel random aperture approach. The algorithms have been implemented in a stand-alone programme using dose calculations from a commercial treatment planning system. For this study, the treatment planning system Pinnacle from Philips has been used and connected to the optimization programme using an ASCII interface. Dose calculations in Pinnacle were performed by Monte Carlo simulations for a remote-controlled electron multileaf collimator (MLC) from Euromechanics. As a result, treatment plans for breast cancer patients could be significantly improved when using randomly generated aperture beams. The combination of beams generated through segmentation and randomization achieved the best results in terms of target coverage and sparing of critical organs. The treatment plans could be further improved by use of a field reduction algorithm. Without a relevant loss in dose distribution, the total number of MLC fields and monitor units could be reduced by up to 20%. In conclusion, using randomized aperture beams is a promising new approach in radiotherapy and exhibits potential for further improvements in dose optimization through a combination of randomized electron and photon aperture beams.

  12. Electro-optical characterization system develped for ATLIDCAS AIV: flat field and collimated beam injections

    NASA Astrophysics Data System (ADS)

    Ramos, G.; Laguna, H.; Torres, J.; Belenguer, T.

    2017-11-01

    In the framework of the ESA EarthCare Mission, an atmospheric LIDAR (ATLID) was included as a payload. CAS is the co-alignment system of such a LIDAR instrument, the system responsible of guaranteeing the proper alignment of the projected laser beam and the reflected light collected. Within CAS, in which a consortium leaded by ASTRIUM France is working in, as well as CRISA (electronics) and LIDAX (mechanical engineering), INTA is in charge of the development of the instrumentation to be used on ground (on ground support equipments, OGSEs) needed for the proper electro-optical characterization.

  13. Development of stereotactic radiosurgery using carbon beams (carbon-knife)

    NASA Astrophysics Data System (ADS)

    Keawsamur, Mintra; Matsumura, Akihiko; Souda, Hikaru; Kano, Yosuke; Torikoshi, Masami; Nakano, Takashi; Kanai, Tatsuaki

    2018-02-01

    The aim of this research is to develop a stereotactic-radiosurgery (SRS) technique using carbon beams to treat small intracranial lesions; we call this device the carbon knife. A 2D-scanning method is adapted to broaden a pencil beam to an appropriate size for an irradiation field. A Mitsubishi slow extraction using third order resonance through a rf acceleration system stabilized by a feed-forward scanning beam using steering magnets with a 290 MeV/u initial beam energy was used for this purpose. Ridge filters for spread-out Bragg peaks (SOBPs) with widths of 5 mm, 7.5 mm, and 10 mm were designed to include fluence-attenuation effects. The collimator, which defines field shape, was used to reduce the lateral penumbra. The lateral-penumbra width at the SOBP region was less than 2 mm for the carbon knife. The penumbras behaved almost the same when changing the air gap, but on the other hand, increasing the range-shifter thickness mostly broadened the lateral penumbra. The physical-dose rates were approximate 6 Gy s-1 and 4.5 Gy s-1 for the 10  ×  10 mm2 and 5  ×  5 mm2 collimators, respectively.

  14. Theoretical Benefits of Dynamic Collimation in Pencil Beam Scanning Proton Therapy for Brain Tumors: Dosimetric and Radiobiological Metrics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moignier, Alexandra, E-mail: alexandra-moignier@uiowa.edu; Gelover, Edgar; Wang, Dongxu

    Purpose: To quantify the dosimetric benefit of using a dynamic collimation system (DCS) for penumbra reduction during the treatment of brain tumors by pencil beam scanning proton therapy (PBS PT). Methods and Materials: Collimated and uncollimated brain treatment plans were created for 5 patients previously treated with PBS PT and retrospectively enrolled in an institutional review board–approved study. The in-house treatment planning system, RDX, was used to generate the plans because it is capable of modeling both collimated and uncollimated beamlets. The clinically delivered plans were reproduced with uncollimated plans in terms of target coverage and organ at risk (OAR) sparingmore » to ensure a clinically relevant starting point, and collimated plans were generated to improve the OAR sparing while maintaining target coverage. Physical and biological comparison metrics, such as dose distribution conformity, mean and maximum doses, normal tissue complication probability, and risk of secondary brain cancer, were used to evaluate the plans. Results: The DCS systematically improved the dose distribution conformity while preserving the target coverage. The average reduction of the mean dose to the 10-mm ring surrounding the target and the healthy brain were 13.7% (95% confidence interval [CI] 11.6%-15.7%; P<.0001) and 25.1% (95% CI 16.8%-33.4%; P<.001), respectively. This yielded an average reduction of 24.8% (95% CI 0.8%-48.8%; P<.05) for the brain necrosis normal tissue complication probability using the Flickinger model, and 25.1% (95% CI 16.8%-33.4%; P<.001) for the risk of secondary brain cancer. A general improvement of the OAR sparing was also observed. Conclusion: The lateral penumbra reduction afforded by the DCS increases the normal tissue sparing capabilities of PBS PT for brain cancer treatment while preserving target coverage.« less

  15. Micro-crystallography developments at GM/CA CAT at the APS.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, S.; Makarov, O.; Benn, R.

    2010-01-01

    Recently, several important structures have been solved using micro-crystallographic techniques that previously could not have been solved with conventional crystallography. At GM/CA-CAT we continue to develop micro-crystallographic capabilities for difficult problems such as small crystals of large macromolecular complexes or membrane proteins grown in the lipidic cubic phase. This paper will describe three major upgrades to our arsenal of tools, 'mini-beam' collimators, active beamstop, and an improved goniostat. Our 'mini-beam' collimators have evolved to a new triple-collimator fabricated from molybdenum as a uni-body. This has significantly improved the robustness, ease of initial alignment, and reduction of background. More recently, twomore » prototypes of a quad-collimator have been developed and fabricated to provide a selection of mini-beams of 5, 10, 20 {mu}m and a 300 {mu}m scatter-guard on a single body. The smaller beams and samples have increased the demand on the tolerances of our goniostat. To meet these challenges we have designed and implemented a goniostat with a 1-micron peak-to-peak sphere of confusion. This is a significant improvement over the previous 6 micron sphere of confusion of the commercially available air-bearing and XY stages. Finally, an 'active beamstop' has been constructed. This will provide non-invasive, real time feedback at the sample during data collection.« less

  16. Micro-Crystallography Developments at GM/CA-CAT at the APS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu Shenglan; Makarov, Oleg; Benn, Rich

    2010-06-23

    Recently, several important structures have been solved using micro-crystallographic techniques that previously could not have been solved with conventional crystallography. At GM/CA-CAT we continue to develop micro-crystallographic capabilities for difficult problems such as small crystals of large macromolecular complexes or membrane proteins grown in the lipidic cubic phase. This paper will describe three major upgrades to our arsenal of tools, 'mini-beam' collimators, active beamstop, and an improved goniostat. Our 'mini-beam' collimators have evolved to a new triple-collimator fabricated from molybdenum as a uni-body. This has significantly improved the robustness, ease of initial alignment, and reduction of background. More recently, twomore » prototypes of a quad-collimator have been developed and fabricated to provide a selection of mini-beams of 5, 10, 20 {mu}m and a 300 {mu}m scatter-guard on a single body. The smaller beams and samples have increased the demand on the tolerances of our goniostat. To meet these challenges we have designed and implemented a goniostat with a 1-micron peak-to-peak sphere of confusion. This is a significant improvement over the previous 6 micron sphere of confusion of the commercially available air-bearing and XY stages. Finally, an 'active beamstop' has been constructed. This will provide non-invasive, real time feedback at the sample during data collection.« less

  17. SU-E-T-804: Verification of the BJR-25 Method of KQ Determination for CyberKnife Absolute Dosimetry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gersh, J; Spectrum Medical Physics, LLC - Greenville, SC; Willett, B

    2015-06-15

    Purpose: Absolute calibration of the CyberKnife is performed using a 6cm-diameter cone defined at 80cm SAD. Since kQ is defined using PDD values determined using 10×10 cm fields at 100cm SSD, the PDD must be corrected in order to correctly apply the quality conversion factor. The accepted method is based on equivalent field-size conversions of PDD values using BJR25. Using the new InCise MLC system, the CK is capable of generating a rectangular field equivalent to 10×10 cm square field. In this study, a comparison is made between kQ values determined using the traditional BJR25 method and the MLC methodmore » introduced herein. Methods: First, kQ(BJR) is determined: a PDD is acquired using a 6cm circular field at 100cm SSD, its field size converted to an equivalent square, and PDD converted to a 10×10cm field using the appropriate BJR25 table. Maintaining a consistent setup, the collimator is changed, and the MLC method is used. Finally, kQ is determined using PDDs acquired with a 9.71×10.31cm at 100cm SSD. This field is produced by setting the field to a size of 7.77×8.25cm (since it is defined at 80cm SAD). An exact 10×10cm field since field size is relegated to increments of its leaf width (0.25cm). This comparison is made using an Exradin A1SL, IBA CC08, IBA CC13, and an Exradin A19. For each detector and collimator type, the beam injector was adjusted to give 5 different beam qualities; representing a range of clinical systems. Results: Averaging across all beam qualities, kQ(MLC) differed from kQ(BJR) by less than 0.15%. The difference between the values increased with detector volume. Conclusion: For CK users with standard cone collimators, the BJR25 method has been verified. For CK users the MLC system, a technique is described to determine kQ. Primary author is the President/Owner of Spectrum Medical Physics, LLC, a company which maintains contracts with Siemens Healthcare and Standard Imaging, Inc.« less

  18. Energy modulated electron therapy: Design, implementation, and evaluation of a novel method of treatment planning and delivery

    NASA Astrophysics Data System (ADS)

    Al-Yahya, Khalid

    Energy modulated electron therapy (EMET) is a promising treatment modality that has the fundamental capabilities to enhance the treatment planning and delivery of superficially located targets. Although it offers advantages over x-ray intensity modulated radiation therapy (IMRT), EMET has not been widely implemented to the same level of accuracy, automation, and clinical routine as its x-ray counterpart. This lack of implementation is attributed to the absence of a remotely automated beam shaping system as well as the deficiency in dosimetric accuracy of clinical electron pencil beam algorithms in the presence of beam modifiers and tissue heterogeneities. In this study, we present a novel technique for treatment planning and delivery of EMET. The delivery is achieved using a prototype of an automated "few leaf electron collimator" (FLEC). It consists of four copper leaves driven by stepper motors which are synchronized with the x-ray jaws in order to form a series of collimated rectangular openings or "fieldlets". Based on Monte Carlo studies, the FLEC has been designed to serve as an accessory tool to the current accelerator equipment. The FLEC was constructed and its operation was fully automated and integrated with the accelerator through an in-house assembled control unit. The control unit is a portable computer system accompanied with customized software that delivers EMET plans after acquiring them from the optimization station. EMET plans are produced based on dose volume constraints that employ Monte Carlo pre-generated and patient-specific kernels which are utilized by an in-house developed optimization algorithm. The structure of the optimization software is demonstrated. Using Monte Carlo techniques to calculate dose allows for accurate modeling of the collimation system as well as the patient heterogeneous geometry and take into account their impact on optimization. The Monte Carlo calculations were validated by comparing them against output measurements with an ionization chamber. Comparisons with measurements using nearly energy-independent radiochromic films were performed to confirm the Monte Carlo calculation accuracy for 1-D and 2-D dose distributions. We investigated the clinical significance of EMET on cancer sites that are inherently difficult to plan with IMRT. Several parameters were used to analyze treatment plans where they show that EMET provides significant overall improvements over IMRT.

  19. Light beam frequency comb generator

    DOEpatents

    Priatko, G.J.; Kaskey, J.A.

    1992-11-24

    A light beam frequency comb generator uses an acousto-optic modulator to generate a plurality of light beams with frequencies which are uniformly separated and possess common noise and drift characteristics. A well collimated monochromatic input light beam is passed through this modulator to produce a set of both frequency shifted and unshifted optical beams. An optical system directs one or more frequency shifted beams along a path which is parallel to the path of the input light beam such that the frequency shifted beams are made incident on the modulator proximate to but separated from the point of incidence of the input light beam. After the beam is thus returned to and passed through the modulator repeatedly, a plurality of mutually parallel beams are generated which are frequency-shifted different numbers of times and possess common noise and drift characteristics. 2 figs.

  20. Light beam frequency comb generator

    DOEpatents

    Priatko, Gordon J.; Kaskey, Jeffrey A.

    1992-01-01

    A light beam frequency comb generator uses an acousto-optic modulator to generate a plurality of light beams with frequencies which are uniformly separated and possess common noise and drift characteristics. A well collimated monochromatic input light beam is passed through this modulator to produce a set of both frequency shifted and unshifted optical beams. An optical system directs one or more frequency shifted beams along a path which is parallel to the path of the input light beam such that the frequency shifted beams are made incident on the modulator proximate to but separated from the point of incidence of the input light beam. After the beam is thus returned to and passed through the modulator repeatedly, a plurality of mutually parallel beams are generated which are frequency-shifted different numbers of times and possess common noise and drift characteristics.

  1. Deriving detector-specific correction factors for rectangular small fields using a scintillator detector.

    PubMed

    Qin, Yujiao; Zhong, Hualiang; Wen, Ning; Snyder, Karen; Huang, Yimei; Chetty, Indrin J

    2016-11-08

    The goal of this study was to investigate small field output factors (OFs) for flat-tening filter-free (FFF) beams on a dedicated stereotactic linear accelerator-based system. From this data, the collimator exchange effect was quantified, and detector-specific correction factors were generated. Output factors for 16 jaw-collimated small fields (from 0.5 to 2 cm) were measured using five different detectors including an ion chamber (CC01), a stereotactic field diode (SFD), a diode detector (Edge), Gafchromic film (EBT3), and a plastic scintillator detector (PSD, W1). Chamber, diodes, and PSD measurements were performed in a Wellhofer water tank, while films were irradiated in solid water at 100 cm source-to-surface distance and 10 cm depth. The collimator exchange effect was quantified for rectangular fields. Monte Carlo (MC) simulations of the measured configurations were also performed using the EGSnrc/DOSXYZnrc code. Output factors measured by the PSD and verified against film and MC calculations were chosen as the benchmark measurements. Compared with plastic scintillator detector (PSD), the small volume ion chamber (CC01) underestimated output factors by an average of -1.0% ± 4.9% (max. = -11.7% for 0.5 × 0.5 cm2 square field). The stereotactic diode (SFD) overestimated output factors by 2.5% ± 0.4% (max. = 3.3% for 0.5 × 1 cm2 rectangular field). The other diode detector (Edge) also overestimated the OFs by an average of 4.2% ± 0.9% (max. = 6.0% for 1 × 1 cm2 square field). Gafchromic film (EBT3) measure-ments and MC calculations agreed with the scintillator detector measurements within 0.6% ± 1.8% and 1.2% ± 1.5%, respectively. Across all the X and Y jaw combinations, the average collimator exchange effect was computed: 1.4% ± 1.1% (CC01), 5.8% ± 5.4% (SFD), 5.1% ± 4.8% (Edge diode), 3.5% ± 5.0% (Monte Carlo), 3.8% ± 4.7% (film), and 5.5% ± 5.1% (PSD). Small field detectors should be used with caution with a clear understanding of their behaviors, especially for FFF beams and small, elongated fields. The scintillator detector exhibited good agreement against Gafchromic film measurements and MC simulations over the range of field sizes studied. The collimator exchange effect was found to be impor-tant at these small field sizes. Detector-specific correction factors were computed using the scintillator measurements as the benchmark. © 2016 The Authors.

  2. Two-step tomographic reconstructions of temperature and species concentration in a flame based on laser absorption measurements with a rotation platform

    NASA Astrophysics Data System (ADS)

    Xia, Huihui; Kan, Ruifeng; Xu, Zhenyu; He, Yabai; Liu, Jianguo; Chen, Bing; Yang, Chenguang; Yao, Lu; Wei, Min; Zhang, Guangle

    2017-03-01

    We present a system for accurate tomographic reconstruction of the combustion temperature and H2O vapor concentration of a flame based on laser absorption measurements, in combination with an innovative two-step algebraic reconstruction technique. A total of 11 collimated laser beams generated from outputs of fiber-coupled diode lasers formed a two-dimensional 5 × 6 orthogonal beam grids and measured at two H2O absorption transitions (7154.354/7154.353 cm-1 and 7467.769 cm-1). The measurement system was designed on a rotation platform to achieve a two-folder improvement in spatial resolution. Numerical simulation showed that the proposed two-step algebraic reconstruction technique for temperature and concentration, respectively, greatly improved the reconstruction accuracy of species concentration when compared with a traditional calculation. Experimental results demonstrated the good performances of the measurement system and the two-step reconstruction technique for applications such as flame monitoring and combustion diagnosis.

  3. New type of capillary for use as ion beam collimator and air-vacuum interface

    NASA Astrophysics Data System (ADS)

    Stoytschew, V.; Schulte-Borchers, M.; Božičević Mihalića, Iva; Perez, R. D.

    2016-08-01

    Glass capillaries offer a unique way to combine small diameter ion beam collimation with an air-vacuum interface for ambient pressure ion beam applications. Usually they have an opening diameter of a few microns, limiting the air inflow sufficiently to maintain stable conditions on the vacuum side. As the glass capillaries generally are quite thin and fragile, handling of the capillary in the experiment becomes difficult. They also introduce an X-ray background produced by the capillary wall material, which has to be shielded or subtracted from the data for Particle Induced X-ray Emission (PIXE) applications. To overcome both drawbacks, a new type of conical glass capillary has been developed. It has a higher wall thickness eliminating the low energy X-ray background produced by common capillaries and leading to a more robust lens. The results obtained in first tests show, that this new capillary is suitable for ion beam collimation and encourage further work on the capillary production process to provide thick wall capillaries with an outlet diameter in the single digit micro- or even nanometre range.

  4. Variable Magnification With Kirkpatrick-Baez Optics for Synchrotron X-Ray Microscopy

    PubMed Central

    Jach, Terrence; Bakulin, Alex S.; Durbin, Stephen M.; Pedulla, Joseph; Macrander, Albert

    2006-01-01

    We describe the distinction between the operation of a short focal length x-ray microscope forming a real image with a laboratory source (convergent illumination) and with a highly collimated intense beam from a synchrotron light source (Köhler illumination). We demonstrate the distinction with a Kirkpatrick-Baez microscope consisting of short focal length multilayer mirrors operating at an energy of 8 keV. In addition to realizing improvements in the resolution of the optics, the synchrotron radiation microscope is not limited to the usual single magnification at a fixed image plane. Higher magnification images are produced by projection in the limit of geometrical optics with a collimated beam. However, in distinction to the common method of placing the sample behind the optical source of a diverging beam, we describe the situation in which the sample is located in the collimated beam before the optical element. The ultimate limits of this magnification result from diffraction by the specimen and are determined by the sample position relative to the focal point of the optic. We present criteria by which the diffraction is minimized. PMID:27274930

  5. Three-dimensional propagation and absorption of high frequency Gaussian beams in magnetoactive plasmas

    NASA Astrophysics Data System (ADS)

    Nowak, S.; Orefice, A.

    1994-05-01

    In today's high frequency systems employed for plasma diagnostics, power heating, and current drive the behavior of the wave beams is appreciably affected by the self-diffraction phenomena due to their narrow collimation. In the present article the three-dimensional propagation of Gaussian beams in inhomogeneous and anisotropic media is analyzed, starting from a properly formulated dispersion relation. Particular attention is paid, in the case of electromagnetic electron cyclotron (EC) waves, to the toroidal geometry characterizing tokamak plasmas, to the power density evolution on the advancing wave fronts, and to the absorption features occurring when a beam crosses an EC resonant layer.

  6. 2000W high beam quality diode laser for direct materials processing

    NASA Astrophysics Data System (ADS)

    Qin, Wen-bin; Liu, You-qiang; Cao, Yin-hua; Gao, Jing; Pan, Fei; Wang, Zhi-yong

    2011-11-01

    This article describes high beam quality and kilowatt-class diode laser system for direct materials processing, using optical design software ZEMAX® to simulate the diode laser optical path, including the beam shaping, collimation, coupling, focus, etc.. In the experiment, the diode laser stack of 808nm and the diode laser stack of 915nm were used for the wavelength coupling, which were built vertical stacks up to 16 bars. The threshold current of the stack is 6.4A, the operating current is 85A and the output power is 1280W. Through experiments, after collimating the diode laser beam with micro-lenses, the fast axis BPP of the stack is less than 60mm.mrad, and the slow-axis BPP of the stack is less than 75mm.mrad. After shaping the laser beam and improving the beam quality, the fast axis BPP of the stack is still 60mm.mrad, and the slow-axis BPP of the stack is less than 19mm.mrad. After wavelength coupling and focusing, ultimately the power of 2150W was obtained, focal spot size of 1.5mm * 1.2mm with focal length 300mm. The laser power density is 1.2×105W/cm2, and that can be used for metal remelting, alloying, cladding and welding. The total optical coupling conversion efficiency is 84%, and the total electrical - optical conversion efficiency is 50%.

  7. Heavy-ion conformal irradiation in the shallow-seated tumor therapy terminal at HIRFL.

    PubMed

    Li, Qiang; Dai, Zhongying; Yan, Zheng; Jin, Xiaodong; Liu, Xinguo; Xiao, Guoqing

    2007-11-01

    Basic research related to heavy-ion cancer therapy has been done at the Institute of Modern Physics (IMP), Chinese Academy of Sciences since 1995. Now a plan of clinical trial with heavy ions has been launched at IMP. First, superficially placed tumor treatment with heavy ions is expected in the therapy terminal at the Heavy Ion Research Facility in Lanzhou (HIRFL), where carbon ion beams with energy up to 100 MeV/u can be supplied. The shallow-seated tumor therapy terminal at HIRFL is equipped with a passive beam delivery system including two orthogonal dipole magnets, which continuously scan pencil beams laterally and generate a broad and uniform irradiation field, a motor-driven energy degrader and a multi-leaf collimator. Two different types of range modulator, ripple filter and ridge filter with which Guassian-shaped physical dose and uniform biological effective dose Bragg peaks can be shaped for therapeutic ion beams respectively, have been designed and manufactured. Therefore, two-dimensional and three-dimensional conformal irradiations to tumors can be performed with the passive beam delivery system at the earlier therapy terminal. Both the conformal irradiation methods have been verified experimentally and carbon-ion conformal irradiations to patients with superficially placed tumors have been carried out at HIRFL since November 2006.

  8. The telecommunications and data acquisition report

    NASA Technical Reports Server (NTRS)

    Renzetti, N. A. (Editor)

    1982-01-01

    Developments in Earth-based radio technology are reported. The Deep Space Network is discussed in terms of its advanced systems, network and facility engineering and implementation, operations, and energy sources. Problems in pulse communication and radio frequency interference are addressed with emphasis on pulse position modulation and laser beam collimation.

  9. High-speed volume measurement system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lane, Michael H.; Doyle, Jr., James L.; Brinkman, Michael J.

    2018-01-30

    Disclosed is a volume sensor having a first axis, a second axis, and a third axis, each axis including a laser source configured to emit a beam; a parallel beam generating assembly configured to receive the beam and split the beam into a first parallel beam and a second parallel beam, a beam-collimating assembly configured to receive the first parallel beam and the second parallel beam and output a first beam sheet and a second beam sheet, the first beam sheet and the second beam sheet being configured to traverse the object aperture; a first collecting lens and a secondmore » collecting lens; and a first photodetector and a second photodetector, the first photodetector and the second photodetector configured to output an electrical signal proportional to the object; wherein the first axis, the second axis, and the third axis are arranged at an angular offset with respect to each other.« less

  10. Analysis of Neutron Production in Passively Scattered Ion-Beam Therapy.

    PubMed

    Heo, Seunguk; Yoo, Seunghoon; Song, Yongkeun; Kim, Eunho; Shin, Jaeik; Han, Soorim; Jung, Wongyun; Nam, Sanghee; Lee, Rena; Lee, Kitae; Cho, Sungho

    2017-07-01

    A new treatment facility for heavy ion therapy since 2010 was constructed. In the broad beam, a range shifter, ridge filter and multi leaf collimator (MLC) for the generation of the spread-out Bragg peak is used. In this case, secondary neutrons produced by the interactions of the ion field with beam-modifying devices (e.g. double-scattering system, beam shaping collimators and range compensators) are very important for patient safety. Therefore, these components must be carefully examined in the context of secondary neutron yield and associated secondary cancer risk. In this article, Monte Carlo simulation has been carried out with the FLUktuierende KAskade particle transport code, the fluence and distribution of neutron generation and the neutron dose equivalent from the broad beam components are compared using carbon and proton beams. As a result, it is confirmed that the yield of neutron production using a carbon beam from all components of the broad beam was higher than using a proton beam. The ambient dose by neutrons per heavy ion and proton ion from the MLC surface was 0.12-0.18 and 0.0067-0.0087 pSv, respectively, which shows that heavy ions generate more neutrons than protons. However, ambient dose per treatment 2 Gy, which means physical dose during treatment by ion beam, is higher than carbon beam because proton therapy needs more beam flux to make 2-Gy prescription dose. Therefore, the neutron production from the MLC, which is closed to the patient, is a very important parameter for patient safety. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Steering and collimating ballistic electrons with amphoteric refraction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Radu, A.; Dragoman, D.; Iftimie, S.

    2012-07-15

    We show that amphoteric refraction of ballistic electrons, i.e., positive or negative refraction depending on the incidence angle, occurs at an interface between an isotropic and an anisotropic medium and can be employed to steer and collimate electron beams. The steering angle is determined by the materials' parameters, but the degree of collimation can be tuned in a significant range by changing the energy of ballistic electrons.

  12. Collimated thermal radiation transfer via half Maxwell's fish-eye lens for thermophotovoltaics

    NASA Astrophysics Data System (ADS)

    Chung, Haejun; Zhou, Zhiguang; Bermel, Peter

    2017-05-01

    Thermophotovoltaics (TPV) convert heat into electricity by capturing thermal radiation with a photovoltaic (PV) cell, ideally at efficiencies of 50% or more. However, excess heating of the PV cell from close proximity to the emitter substantially reduces the system efficiency. In this work, we theoretically develop and numerically demonstrate an approach to fundamentally improving TPV systems that allow for a much greater separation of an emitter and a receiver. Thus, we solve the excess heating dilemma, required for achieving theoretically high efficiencies. It consists of a spherically graded index lens known as Maxwell's Fish-Eye (MFE) structure, capable of collimating hemispherical emission into a much narrower range of angles, close to the normal direction. To fully characterize the power radiation profile of the MFE, we perform finite-difference time-domain simulations for a quarter MFE and then map it onto a Gaussian beam approximation. The modeled beam properties are subsequently used to study a half MFE. In an optimized half MFE design, 90% of all thermal photons reach a receiver at a distance of 100 λ; by comparison, only 15.6% of a blackbody emitter reach a receiver in the same geometry. It is also shown that the emission achieved by a half MFE can lead to a photon recycling rate above 95% for below bandgap photons at an emitter-receiver separation of 100 λ. By applying a half MFE, the absolute TPV efficiency can be improved from 5.74% to 37.15%, which represents a significant step forward in realizing high-efficiency TPV systems.

  13. Near field of an oscillating electric dipole and cross-polarization of a collimated beam of light: Two sides of the same coin

    NASA Astrophysics Data System (ADS)

    Aiello, Andrea; Ornigotti, Marco

    2014-09-01

    We address the question of whether there exists a hidden relationship between the near-field distribution generated by an oscillating electric dipole and the so-called cross-polarization of a collimated beam of light. We find that the answer is affirmative by showing that the complex field distributions occurring in both cases have a common physical origin: the requirement that the electromagnetic fields must be transverse.

  14. Laser goniometer

    DOEpatents

    Fairer, George M.; Boernge, James M.; Harris, David W.; Campbell, DeWayne A.; Tuttle, Gene E.; McKeown, Mark H.; Beason, Steven C.

    1993-01-01

    The laser goniometer is an apparatus which permits an operator to sight along a geologic feature and orient a collimated lamer beam to match the attitude of the feature directly. The horizontal orientation (strike) and the angle from horizontal (dip), are detected by rotary incremental encoders attached to the laser goniometer which provide a digital readout of the azimuth and tilt of the collimated laser beam. A microprocessor then translates the square wave signal encoder outputs into an ASCII signal for use by data recording equipment.

  15. Assessment of human exposure doses received by activation of medical linear accelerator components

    NASA Astrophysics Data System (ADS)

    Lee, D.-Y.; Kim, J.-H.; Park, E.-T.

    2017-08-01

    This study analyzes the radiation exposure dose that an operator can receive from radioactive components during maintenance or repair of a linear accelerator. This study further aims to evaluate radiological safety. Simulations are performed on 10 MV and 15 MV photon beams, which are the most frequently used high-energy beams in clinics. The simulation analyzes components in order of activity and the human exposure dose based on the amount of neutrons received. As a result, the neutron dose, radiation dose, and human exposure dose are ranked in order of target, primary collimator, flattening filter, multi-leaf collimator, and secondary collimator, where the minimum dose is 9.34E-07 mSv/h and the maximum is 1.71E-02 mSv/h. When applying the general dose limit (radiation worker 20 mSv/year, pubic 1 mSv/year) in accordance with the Nuclear Safety Act, all components of a linear accelerator are evaluated as below the threshold value. Therefore, the results suggest that there is no serious safety issue for operators in maintaining and repairing a linear accelerator. Nevertheless, if an operator recognizes an exposure from the components of a linear accelerator during operation and considers the operating time and shielding against external exposure, exposure of the operator is expected to be minimized.

  16. Measurements from a Compact Cost-Effective Beamline for the THC14 PET Cyclotron

    NASA Astrophysics Data System (ADS)

    Dehnel, M. P.; Theroux, J.; Christensen, T.; Stewart, T. M.; Roeder, M.; Sirot, P.; Fasse, D.; Brasile, J. P.; Raoult, F.; Buckley, K.

    2009-03-01

    The THC14 PET Cyclotron produced by THALES specifies two compact cost-effective beamlines for high current PET radioisotope production. The design and development of the beamline system was reported previously in NIM B 261 (2007) pp 809-812. This paper describes the successful testing of this compact beamline at the first installation. A series of measurement data are presented starting from low current scintillator image data, higher current beam diagnostic data (baffles, collimators, targets) and finally a simultaneous dual beam run on Faraday Cups. The beamline system has proven to be a flexible and valuable tool for optimizing high current beam intensity distribution on target in a well-instrumented manner. This ability to tailor the beam characteristics for the target is particularly important as high power targets are developed which can handle very high beam currents.

  17. Holographic Plossl Retroreflectors

    NASA Technical Reports Server (NTRS)

    Waluschka, Eugene

    2006-01-01

    Holographic retroreflectors that function equivalently to Plossl eyepieces have been developed and used in free-space optical communication systems that utilize laser beams. Plossl eyepieces are well known among telescope designers. They have been adopted for use a retroreflectors and as focusing elements (for reception) and collimating elements (for transmission) in optical communication systems. A retro-reflector that incorporates a Plossl eyepiece is termed a cat's-eye retroreflector.

  18. Quality control methods for linear accelerator radiation and mechanical axes alignment.

    PubMed

    Létourneau, Daniel; Keller, Harald; Becker, Nathan; Amin, Md Nurul; Norrlinger, Bernhard; Jaffray, David A

    2018-06-01

    The delivery accuracy of highly conformal dose distributions generated using intensity modulation and collimator, gantry, and couch degrees of freedom is directly affected by the quality of the alignment between the radiation beam and the mechanical axes of a linear accelerator. For this purpose, quality control (QC) guidelines recommend a tolerance of ±1 mm for the coincidence of the radiation and mechanical isocenters. Traditional QC methods for assessment of radiation and mechanical axes alignment (based on pointer alignment) are time consuming and complex tasks that provide limited accuracy. In this work, an automated test suite based on an analytical model of the linear accelerator motions was developed to streamline the QC of radiation and mechanical axes alignment. The proposed method used the automated analysis of megavoltage images of two simple task-specific phantoms acquired at different linear accelerator settings to determine the coincidence of the radiation and mechanical isocenters. The sensitivity and accuracy of the test suite were validated by introducing actual misalignments on a linear accelerator between the radiation axis and the mechanical axes using both beam steering and mechanical adjustments of the gantry and couch. The validation demonstrated that the new QC method can detect sub-millimeter misalignment between the radiation axis and the three mechanical axes of rotation. A displacement of the radiation source of 0.2 mm using beam steering parameters was easily detectable with the proposed collimator rotation axis test. Mechanical misalignments of the gantry and couch rotation axes of the same magnitude (0.2 mm) were also detectable using the new gantry and couch rotation axis tests. For the couch rotation axis, the phantom and test design allow detection of both translational and tilt misalignments with the radiation beam axis. For the collimator rotation axis, the test can isolate the misalignment between the beam radiation axis and the mechanical collimator rotation axis from the impact of field size asymmetry. The test suite can be performed in a reasonable time (30-35 min) due to simple phantom setup, prescription-based beam delivery, and automated image analysis. As well, it provides a clear description of the relationship between axes. After testing the sensitivity of the test suite to beam steering and mechanical errors, the results of the test suite were used to reduce the misalignment errors of the linac to less than 0.7-mm radius for all axes. The proposed test suite offers sub-millimeter assessment of the coincidence of the radiation and mechanical isocenters and the test automation reduces complexity with improved efficiency. The test suite results can be used to optimize the linear accelerator's radiation to mechanical isocenter alignment by beam steering and mechanical adjustment of gantry and couch. © 2018 American Association of Physicists in Medicine.

  19. VMAT optimization with dynamic collimator rotation.

    PubMed

    Lyu, Qihui; O'Connor, Daniel; Ruan, Dan; Yu, Victoria; Nguyen, Dan; Sheng, Ke

    2018-04-16

    Although collimator rotation is an optimization variable that can be exploited for dosimetric advantages, existing Volumetric Modulated Arc Therapy (VMAT) optimization uses a fixed collimator angle in each arc and only rotates the collimator between arcs. In this study, we develop a novel integrated optimization method for VMAT, accounting for dynamic collimator angles during the arc motion. Direct Aperture Optimization (DAO) for Dynamic Collimator in VMAT (DC-VMAT) was achieved by adding to the existing dose fidelity objective an anisotropic total variation term for regulating the fluence smoothness, a binary variable for forming simple apertures, and a group sparsity term for controlling collimator rotation. The optimal collimator angle for each beam angle was selected using the Dijkstra's algorithm, where the node costs depend on the estimated fluence map at the current iteration and the edge costs account for the mechanical constraints of multi-leaf collimator (MLC). An alternating optimization strategy was implemented to solve the DAO and collimator angle selection (CAS). Feasibility of DC-VMAT using one full-arc with dynamic collimator rotation was tested on a phantom with two small spherical targets, a brain, a lung and a prostate cancer patient. The plan was compared against a static collimator VMAT (SC-VMAT) plan using three full arcs with 60 degrees of collimator angle separation in patient studies. With the same target coverage, DC-VMAT achieved 20.3% reduction of R50 in the phantom study, and reduced the average max and mean OAR dose by 4.49% and 2.53% of the prescription dose in patient studies, as compared with SC-VMAT. The collimator rotation co-ordinated with the gantry rotation in DC-VMAT plans for deliverability. There were 13 beam angles in the single-arc DC-VMAT plan in patient studies that requires slower gantry rotation to accommodate multiple collimator angles. The novel DC-VMAT approach utilizes the dynamic collimator rotation during arc delivery. In doing so, DC-VMAT affords more sophisticated intensity modulation, alleviating the limitation previously imposed by the square beamlet from the MLC leaf thickness and achieves higher effective modulation resolution. Consequently, DC-VMAT with a single arc manages to achieve superior dosimetry than SC-VMAT with three full arcs. © 2018 American Association of Physicists in Medicine.

  20. A new method of determining moisture gradient in wood

    Treesearch

    Zhiyong Cai

    2008-01-01

    Moisture gradient in wood and wood composites is one of most important factors that affects both physical stability and mechanical performance. This paper describes a method for measuring moisture gradient in lumber and engineering wood composites as it varies across material thickness. This innovative method employs a collimated radiation beam (x rays or [gamma] rays...

  1. Method for selecting minimum width of leaf in multileaf adjustable collimator while inhibiting passage of particle beams of radiation through sawtooth joints between collimator leaves

    DOEpatents

    Ludewigt, Bernhard; Bercovitz, John; Nyman, Mark; Chu, William

    1995-01-01

    A method is disclosed for selecting the minimum width of individual leaves of a multileaf adjustable collimator having sawtooth top and bottom surfaces between adjacent leaves of a first stack of leaves and sawtooth end edges which are capable of intermeshing with the corresponding sawtooth end edges of leaves in a second stack of leaves of the collimator. The minimum width of individual leaves in the collimator, each having a sawtooth configuration in the surface facing another leaf in the same stack and a sawtooth end edge, is selected to comprise the sum of the penetration depth or range of the particular type of radiation comprising the beam in the particular material used for forming the leaf; plus the total path length across all the air gaps in the area of the joint at the edges between two leaves defined between lines drawn across the peaks of adjacent sawtooth edges; plus at least one half of the length or period of a single sawtooth. To accomplish this, in accordance with the method of the invention, the penetration depth of the particular type of radiation in the particular material to be used for the collimator leaf is first measured. Then the distance or gap between adjoining or abutting leaves is selected, and the ratio of this distance to the height of the sawteeth is selected. Finally the number of air gaps through which the radiation will pass between sawteeth is determined by selecting the number of sawteeth to be formed in the joint. The measurement and/or selection of these parameters will permit one to determine the minimum width of the leaf which is required to prevent passage of the beam through the sawtooth joint.

  2. An optical fiber guided ultrasonic excitation and sensing system for online monitoring of nuclear power plants

    NASA Astrophysics Data System (ADS)

    Yang, J.; Lee, H.; Sohn, H.

    2012-05-01

    This study presents an embedded laser ultrasonic system for pipeline monitoring under high temperature environment. Recently, laser ultrasonics is becoming popular because of their advantageous characteristics such as (a) noncontact inspection, (b) immunity against electromagnetic interference (EMI), and (c) applicability under high temperature. However, the performance of conventional laser ultrasonic techniques for pipeline monitoring has been limited because many pipelines are covered by insulating materials and target surfaces are inaccessible. To overcome the problem, this study designs an embeddable optical fibers and fixing devices that deliver laser beams from laser sources to a target pipe using embedded optical fibers. For guided wave generation, an optical fiber is furnished with a beam collimator for irradiating a laser beam onto a target structure. The corresponding response is measured based on the principle of laser interferometry. Light from a monochromatic source is colliminated and delivered to a target surface by another optical with a focusing module, and reflected light is transmitted back to the interferometer through the same fiber. The feasibility of the proposed system for embedded ultrasonic measurement has been experimentally verified using a pipe specimen under high temperature.

  3. Investigation of converging and collimated beam instrument geometry on specular gloss measurements

    NASA Astrophysics Data System (ADS)

    Zwinkels, Joanne C.; Côté, Éric; Morgan, John

    2018-02-01

    Specular gloss is an important appearance property of a wide variety of manufactured goods. Depending upon the application, e.g. paints, paper, ceramics, etc. different instrument designs and measurement geometries are specified in standard test methods. For a given specular angle, these instrument designs can be broadly classified as converging beam (TAPPI method) and collimated beam (DIN method). In recent comparisons of specular gloss measurements using different glossmeters, very large standard deviations have been reported, well exceeding the manufacturers claims. In this paper, we investigate the effect of instrument beam geometry on gloss measurements. These results indicate that this difference in beam geometry can give the magnitude of gloss differences reported in these comparisons and highlights the importance of educating the user community of best measurement practices and obtaining appropriate traceability for their glossmeters.

  4. 150 {mu}A 18F{sup -} target and beam port upgrade for the IBA 18/9 cyclotron

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stokely, M. H.; Peeples, J. L.; Poorman, M. C.

    2012-12-19

    A high power ({approx}3 kW) target platform has been developed for the IBA 18/9 cyclotron. New designs for the airlock, collimator and target subsystems have been fabricated and deployed. The primary project goal is reliable commercial production of 18F{sup -} at 150 {mu}A or greater, while secondary goals include improving serviceability and extending service intervals relative to OEM systems. Reliable operation in a production environment has been observed at beam currents up to 140 {mu}A. Challenges include ion source lifetime and localized peaking in the beam intensity distribution.

  5. Wavefront Compensation Segmented Mirror Sensing and Control

    NASA Technical Reports Server (NTRS)

    Redding, David C.; Lou, John Z.; Kissil, Andrew; Bradford, Charles M.; Woody, David; Padin, Stephen

    2012-01-01

    The primary mirror of very large submillimeter-wave telescopes will necessarily be segmented into many separate mirror panels. These panels must be continuously co-phased to keep the telescope wavefront error less than a small fraction of a wavelength, to ten microns RMS (root mean square) or less. This performance must be maintained continuously across the full aperture of the telescope, in all pointing conditions, and in a variable thermal environment. A wavefront compensation segmented mirror sensing and control system, consisting of optical edge sensors, Wavefront Compensation Estimator/Controller Soft ware, and segment position actuators is proposed. Optical edge sensors are placed two per each segment-to-segment edge to continuously measure changes in segment state. Segment position actuators (three per segment) are used to move the panels. A computer control system uses the edge sensor measurements to estimate the state of all of the segments and to predict the wavefront error; segment actuator commands are computed that minimize the wavefront error. Translational or rotational motions of one segment relative to the other cause lateral displacement of the light beam, which is measured by the imaging sensor. For high accuracy, the collimator uses a shaped mask, such as one or more slits, so that the light beam forms a pattern on the sensor that permits sensing accuracy of better than 0.1 micron in two axes: in the z or local surface normal direction, and in the y direction parallel to the mirror surface and perpendicular to the beam direction. Using a co-aligned pair of sensors, with the location of the detector and collimated light source interchanged, four degrees of freedom can be sensed: transverse x and y displacements, as well as two bending angles (pitch and yaw). In this approach, each optical edge sensor head has a collimator and an imager, placing one sensor head on each side of a segment gap, with two parallel light beams crossing the gap. Two sets of optical edge sensors are used per segment-to-segment edge, separated by a finite distance along the segment edge, for four optical heads, each with an imager and a collimator. By orienting the beam direction of one edge sensor pair to be +45 away from the segment edge direction, and the other sensor pair to be oriented -45 away from the segment edge direction, all six degrees of freedom of relative motion between the segments can be measured with some redundancy. The software resides in a computer that receives each of the optical edge sensor signals, as well as telescope pointing commands. It feeds back the edge sensor signals to keep the primary mirror figure within specification. It uses a feed-forward control to compensate for global effects such as decollimation of the primary and secondary mirrors due to gravity sag as the telescope pointing changes to track science objects. Three segment position actuators will be provided per segment to enable controlled motions in the piston, tip, and tilt degrees of freedom. These actuators are driven by the software, providing the optical changes needed to keep the telescope phased.

  6. SU-F-BRB-12: A Novel Haar Wavelet Based Approach to Deliver Non-Coplanar Intensity Modulated Radiotherapy Using Sparse Orthogonal Collimators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nguyen, D; Ruan, D; Low, D

    2015-06-15

    Purpose: Existing efforts to replace complex multileaf collimator (MLC) by simple jaws for intensity modulated radiation therapy (IMRT) resulted in unacceptable compromise in plan quality and delivery efficiency. We introduce a novel fluence map segmentation method based on compressed sensing for plan delivery using a simplified sparse orthogonal collimator (SOC) on the 4π non-coplanar radiotherapy platform. Methods: 4π plans with varying prescription doses were first created by automatically selecting and optimizing 20 non-coplanar beams for 2 GBM, 2 head & neck, and 2 lung patients. To create deliverable 4π plans using SOC, which are two pairs of orthogonal collimators withmore » 1 to 4 leaves in each collimator bank, a Haar Fluence Optimization (HFO) method was used to regulate the number of Haar wavelet coefficients while maximizing the dose fidelity to the ideal prescription. The plans were directly stratified utilizing the optimized Haar wavelet rectangular basis. A matching number of deliverable segments were stratified for the MLC-based plans. Results: Compared to the MLC-based 4π plans, the SOC-based 4π plans increased the average PTV dose homogeneity from 0.811 to 0.913. PTV D98 and D99 were improved by 3.53% and 5.60% of the corresponding prescription doses. The average mean and maximal OAR doses slightly increased by 0.57% and 2.57% of the prescription doses. The average number of segments ranged between 5 and 30 per beam. The collimator travel time to create the segments decreased with increasing leaf numbers in the SOC. The two and four leaf designs were 1.71 and 1.93 times more efficient, on average, than the single leaf design. Conclusion: The innovative dose domain optimization based on compressed sensing enables uncompromised 4π non-coplanar IMRT dose delivery using simple rectangular segments that are deliverable using a sparse orthogonal collimator, which only requires 8 to 16 leaves yet is unlimited in modulation resolution. This work is supported in part by Varian Medical Systems, Inc. and NIH R43 CA18339.« less

  7. Radiative transport produced by oblique illumination of turbid media with collimated beams

    NASA Astrophysics Data System (ADS)

    Gardner, Adam R.; Kim, Arnold D.; Venugopalan, Vasan

    2013-06-01

    We examine the general problem of light transport initiated by oblique illumination of a turbid medium with a collimated beam. This situation has direct relevance to the analysis of cloudy atmospheres, terrestrial surfaces, soft condensed matter, and biological tissues. We introduce a solution approach to the equation of radiative transfer that governs this problem, and develop a comprehensive spherical harmonics expansion method utilizing Fourier decomposition (SHEFN). The SHEFN approach enables the solution of problems lacking azimuthal symmetry and provides both the spatial and directional dependence of the radiance. We also introduce the method of sequential-order smoothing that enables the calculation of accurate solutions from the results of two sequential low-order approximations. We apply the SHEFN approach to determine the spatial and angular dependence of both internal and boundary radiances from strongly and weakly scattering turbid media. These solutions are validated using more costly Monte Carlo simulations and reveal important insights regarding the evolution of the radiant field generated by oblique collimated beams spanning ballistic and diffusely scattering regimes.

  8. Mode-mismatched confocal thermal-lens microscope with collimated probe beam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cabrera, Humberto, E-mail: hcabrera@ictp.it; Centro Multidisciplinartio de Ciencias, Instituto Venezolano de Investigaciones Científicas; Korte, Dorota

    2015-05-15

    We report a thermal lens microscope (TLM) based on an optimized mode-mismatched configuration. It takes advantage of the coaxial counter propagating tightly focused excitation and collimated probe beams, instead of both focused at the sample, as it is in currently known TLM setups. A simple mathematical model that takes into account the main features of the instrument is presented. The confocal detection scheme and the introduction of highly collimated probe beam allow enhancing the versatility, limit of detection (LOD), and sensitivity of the instrument. The theory is experimentally verified measuring ethanol’s absorption coefficient at 532.8 nm. Additionally, the presented techniquemore » is applied for detection of ultra-trace amounts of Cr(III) in liquid solution. The achieved LOD is 1.3 ppb, which represents 20-fold enhancement compared to transmission mode spectrometric techniques and a 7.5-fold improvement compared to previously reported methods for Cr(III) based on thermal lens effect.« less

  9. A Compact, High-Flux Cold Atom Beam Source

    NASA Technical Reports Server (NTRS)

    Kellogg, James R.; Kohel, James M.; Thompson, Robert J.; Aveline, David C.; Yu, Nan; Schlippert, Dennis

    2012-01-01

    The performance of cold atom experiments relying on three-dimensional magneto-optical trap techniques can be greatly enhanced by employing a highflux cold atom beam to obtain high atom loading rates while maintaining low background pressures in the UHV MOT (ultra-high vacuum magneto-optical trap) regions. Several techniques exist for generating slow beams of cold atoms. However, one of the technically simplest approaches is a two-dimensional (2D) MOT. Such an atom source typically employs at least two orthogonal trapping beams, plus an additional longitudinal "push" beam to yield maximum atomic flux. A 2D atom source was created with angled trapping collimators that not only traps atoms in two orthogonal directions, but also provides a longitudinal pushing component that eliminates the need for an additional push beam. This development reduces the overall package size, which in turn, makes the 2D trap simpler, and requires less total optical power. The atom source is more compact than a previously published effort, and has greater than an order of magnitude improved loading performance.

  10. Surface dose measurements for highly oblique electron beams.

    PubMed

    Ostwald, P M; Kron, T

    1996-08-01

    Clinical applications of electrons may involve oblique incidence of beams, and although dose variations for angles up to 60 degrees from normal incidence are well documented, no results are available for highly oblique beams. Surface dose measurements in highly oblique beams were made using parallel-plate ion chambers and both standard LiF:Mg, Ti and carbon-loaded LiF Thermoluminescent Dosimeters (TLD). Obliquity factors (OBF) or surface dose at an oblique angle divided by the surface dose at perpendicular incidence, were obtained for electron energies between 4 and 20 MeV. Measurements were performed on a flat solid water phantom without a collimator at 100 cm SSD. Comparisons were also made to collimated beams. The OBFs of surface doses plotted against the angle of incidence increased to a maximum dose followed by a rapid dropoff in dose. The increase in OBF was more rapid for higher energies. The maximum OBF occurred at larger angles for higher-energy beams and ranged from 73 degrees for 4 MeV to 84 degrees for 20 MeV. At the dose maximum, OBFs were between 130% and 160% of direct beam doses, yielding surface doses of up to 150% of Dmax for the 20 MeV beam. At 2 mm depth the dose ratio was found to increase initially with angle and then decrease as Dmax moved closer to the surface. A higher maximum dose was measured at 2 mm depth than at the surface. A comparison of ion chamber types showed that a chamber with a small electrode spacing and large guard ring is required for oblique dose measurement. A semiempirical equation was used to model the dose increase at the surface with different energy electron beams.

  11. SHIELDING CONSIDERATIONS FOR THE SMALL ANIMAL RADIATION RESEARCH PLATFORM (SARRP)

    PubMed Central

    Sayler, Elaine; Dolney, Derek; Avery, Stephen; Koch, Cameron

    2014-01-01

    The Small Animal Radiation Research Platform (SARRP) is a commercially available platform designed to deliver conformal, image-guided radiation to small animals using a dual-anode kV x-ray source. At the University of Pennsylvania, a free-standing 2 m3 enclosure was designed to shield the SARRP according to federal code regulating cabinet x-ray systems. The initial design consisted of 4.0-mm-thick lead for all secondary barriers and proved wholly inadequate. Radiation levels outside the enclosure were 15 times higher than expected. Additionally, the leakage appeared to be distributed broadly within the enclosure, so concern arose that a subject might receive significant doses outside the intended treatment field. Thus, a detailed analysis was undertaken to identify and block all sources of leakage. Leakage sources were identified by Kodak X-OmatV (XV) film placed throughout the enclosure. Radiation inside the enclosure was quantified using Gafchromic film. Outside the enclosure, radiation was measured using a survey meter. Sources of leakage included (1) an unnecessarily broad beam exiting the tube, (2) failure of the secondary collimator to confine the primary beam entirely, (3) scatter from the secondary collimator, (4) lack of beam-stop below the treatment volume, and (5) incomplete shielding of the x-ray tube. The exit window was restricted, and a new collimator was designed to address problems (1–3). A beam-stop and additional tube shielding were installed. These modifications reduced internal scatter by more than 100-fold. Radiation outside the enclosure was reduced to levels compliant with federal regulations, provided the SARRP is operated using tube potentials of 175 kV or less. In addition, these simple and relatively inexpensive modifications eliminate the possibility of exposing a larger animal (such as a rat) to significant doses outside the treatment field. PMID:23532076

  12. WE-EF-BRA-07: High Performance Preclinical Irradiation Through Optimized Dual Focal Spot Dose Painting and Online Virtual Isocenter Radiation Field Targeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stewart, J; Princess Margaret Cancer Centre, University Health Network, Toronto, CA; Lindsay, P

    Purpose: Advances in radiotherapy practice facilitated by collimation systems to shape radiation fields and image guidance to target these conformal beams have motivated proposals for more complex dose patterns to improve the therapeutic ratio. Recent progress in small animal radiotherapy platforms has provided the foundation to validate the efficacy of such interventions, but robustly delivering heterogeneous dose distributions at the scale and accuracy demanded by preclinical studies remains challenging. This work proposes a dual focal spot optimization method to paint spatially heterogeneous dose regions and an online virtual isocenter targeting method to accurately target the dose distributions. Methods: Two-dimensional dosemore » kernels were empirically measured for the 1 mm diameter circular collimator with radiochromic film in a solid water phantom for the small and large x-ray focal spots on the X-RAD 225Cx microirradiator. These kernels were used in an optimization framework which determined a set of animal stage positions, beam-on times, and focal spot settings to optimally deliver a given desired dose distribution. An online method was developed which defined a virtual treatment isocenter based on a single image projection of the collimated radiation field. The method was demonstrated by optimization of a 6 mm circular 2 Gy target adjoining a 4 mm semicircular avoidance region. Results: The dual focal spot technique improved the optimized dose distribution with the proportion of avoidance region receiving more than 0.5 Gy reduced by 40% compared to the large focal spot technique. Targeting tests performed by irradiating ball bearing targets on radiochromic film pieced revealed the online targeting method improved the three-dimensional accuracy from 0.48 mm to 0.15 mm. Conclusion: The dual focal spot optimization and online virtual isocenter targeting framework is a robust option for delivering dose at the preclinical level and provides a new experimental option for unique radiobiological investigations This work is supported, in part, by the Natural Sciences and Engineering Research Council of Canada and a Mitacs-Accelerate fellowship. P.E. Lindsay, and D.A. Jaffray are listed as inventors of the system described herein. This system has been licensed to Precision X-Ray Inc. for commercial development.« less

  13. Conceptual development of the Laser Beam Manifold (LBM)

    NASA Technical Reports Server (NTRS)

    Campbell, W.; Owen, R. B.

    1979-01-01

    The laser beam manifold, a device for transforming a single, narrow, collimated beam of light into several beams of desired intensity ratios is described. The device consists of a single optical substrate with a metallic coating on both optical surfaces. By changing the entry point, the number of outgoing beams can be varied.

  14. On-site audits to investigate the quality of radiation physics of radiation therapy institutions in the Republic of Korea.

    PubMed

    Park, Jong Min; Park, So-Yeon; Chun, Minsoo; Kim, Sang-Tae

    2017-08-01

    To investigate and improve the domestic standard of radiation therapy in the Republic of Korea. On-site audits were performed for 13 institutions in the Republic of Korea. Six items were investigated by on-site visits of each radiation therapy institution, including collimator, gantry, and couch rotation isocenter check; coincidence between light and radiation fields; photon beam flatness and symmetry; electron beam flatness and symmetry; physical wedge transmission factors; and photon beam and electron beam outputs. The average deviations of mechanical collimator, gantry, and couch rotation isocenter were less than 1mm. Those of radiation isocenter were also less than 1mm. The average difference between light and radiation fields was 0.9±0.6mm for the field size of 20cm×20cm. The average values of flatness and symmetry of the photon beams were 2.9%±0.6% and 1.1%±0.7%, respectively. Those of electron beams were 2.5%±0.7% and 0.6%±1.0%, respectively. Every institutions showed wedge transmission factor deviations less than 2% except one institution. The output deviations of both photon and electron beams were less than ±3% for every institution. Through the on-site audit program, we could effectively detect an inappropriately operating linacs and provide some recommendations. The standard of radiation therapy in Korea is expected to improve through such on-site audits. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  15. Testing Instrument for Flight-Simulator Displays

    NASA Technical Reports Server (NTRS)

    Haines, Richard F.

    1987-01-01

    Displays for flight-training simulators rapidly aligned with aid of integrated optical instrument. Calibrations and tests such as aligning boresight of display with respect to user's eyes, checking and adjusting display horizon, checking image sharpness, measuring illuminance of displayed scenes, and measuring distance of optical focus of scene performed with single unit. New instrument combines all measurement devices in single, compact, integrated unit. Requires just one initial setup. Employs laser and produces narrow, collimated beam for greater measurement accuracy. Uses only one moving part, double right prism, to position laser beam.

  16. Simulation of PEP-II Accelerator Backgrounds Using TURTLE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barlow, R.J.; Fieguth, T.; /SLAC

    2006-02-15

    We present studies of accelerator-induced backgrounds in the BaBar detector at the SLAC B-Factory, carried out using LPTURTLE, a modified version of the DECAY TURTLE simulation package. Lost-particle backgrounds in PEP-II are dominated by a combination of beam-gas bremstrahlung, beam-gas Coulomb scattering, radiative-Bhabha events and beam-beam blow-up. The radiation damage and detector occupancy caused by the associated electromagnetic shower debris can limit the usable luminosity. In order to understand and mitigate such backgrounds, we have performed a full program of beam-gas and luminosity-background simulations, that include the effects of the detector solenoidal field, detailed modeling of limiting apertures in bothmore » collider rings, and optimization of the betatron collimation scheme in the presence of large transverse tails.« less

  17. Monte Carlo simulation for coherent backscattering with diverging illumination (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Wu, Wenli; Radosevich, Andrew J.; Eshein, Adam; Nguyen, The-Quyen; Backman, Vadim

    2016-03-01

    Diverging beam illumination is widely used in many optical techniques especially in fiber optic applications and coherence phenomenon is one of the most important properties to consider for these applications. Until now, people have used Monte Carlo simulations to study the backscattering coherence phenomenon in collimated beam illumination only. We are the first one to study the coherence phenomenon under the exact diverging beam geometry by taking into account the impossibility of the existence for the exact time-reversed path pairs of photons, which is the main contribution to the backscattering coherence pattern in collimated beam. In this work, we present a Monte Carlo simulation that considers the influence of the illumination numerical aperture. The simulation tracks the electric field for the unique paths of forward path and reverse path in time-reversed pairs of photons as well as the same path shared by them. With this approach, we can model the coherence pattern formed between the pairs by considering their phase difference at the collection plane directly. To validate this model, we use the Low-coherence Enhanced Backscattering Spectroscopy, one of the instruments looking at the coherence pattern using diverging beam illumination, as the benchmark to compare with. In the end, we show how this diverging configuration would significantly change the coherent pattern under coherent light source and incoherent light source. This Monte Carlo model we developed can be used to study the backscattering phenomenon in both coherence and non-coherence situation with both collimated beam and diverging beam setups.

  18. Study of a high-resolution, 3D positioning cadmium zinc telluride detector for PET.

    PubMed

    Gu, Y; Matteson, J L; Skelton, R T; Deal, A C; Stephan, E A; Duttweiler, F; Gasaway, T M; Levin, C S

    2011-03-21

    This paper investigates the performance of 1 mm resolution cadmium zinc telluride (CZT) detectors for positron emission tomography (PET) capable of positioning the 3D coordinates of individual 511 keV photon interactions. The detectors comprise 40 mm × 40 mm × 5 mm monolithic CZT crystals that employ a novel cross-strip readout with interspersed steering electrodes to obtain high spatial and energy resolution. The study found a single anode FWHM energy resolution of 3.06 ± 0.39% at 511 keV throughout most of the detector volume. Improved resolution is expected with properly shielded front-end electronics. Measurements made using a collimated beam established the efficacy of the steering electrodes in facilitating enhanced charge collection across anodes, as well as a spatial resolution of 0.44 ± 0.07 mm in the direction orthogonal to the electrode planes. Finally, measurements based on coincidence electronic collimation yielded a point spread function with 0.78 ± 0.10 mm FWHM, demonstrating 1 mm spatial resolution capability transverse to the anodes-as expected from the 1 mm anode pitch. These findings indicate that the CZT-based detector concept has excellent performance and shows great promise for a high-resolution PET system.

  19. Sound control by temperature gradients

    NASA Astrophysics Data System (ADS)

    Sánchez-Dehesa, José; Angelov, Mitko I.; Cervera, Francisco; Cai, Liang-Wu

    2009-11-01

    This work reports experiments showing that airborne sound propagation can be controlled by temperature gradients. A system of two heated tubes is here used to demonstrate the collimation and focusing of an ultrasonic beam by the refractive index profile created by the temperature gradients existing around the tubes. Numerical simulations supporting the experimental findings are also reported.

  20. A NUMERICAL CHARACTERIZATION OF PARTICLE BEAM COLLIMATION BY AN AERODYNAMIC LENS-NOZZLE SYSTEM PART I: AN INDIVIDUAL LENS OR NOZZLE. (R825391)

    EPA Science Inventory

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

  1. Differential pencil beam dose computation model for photons.

    PubMed

    Mohan, R; Chui, C; Lidofsky, L

    1986-01-01

    Differential pencil beam (DPB) is defined as the dose distribution relative to the position of the first collision, per unit collision density, for a monoenergetic pencil beam of photons in an infinite homogeneous medium of unit density. We have generated DPB dose distribution tables for a number of photon energies in water using the Monte Carlo method. The three-dimensional (3D) nature of the transport of photons and electrons is automatically incorporated in DPB dose distributions. Dose is computed by evaluating 3D integrals of DPB dose. The DPB dose computation model has been applied to calculate dose distributions for 60Co and accelerator beams. Calculations for the latter are performed using energy spectra generated with the Monte Carlo program. To predict dose distributions near the beam boundaries defined by the collimation system as well as blocks, we utilize the angular distribution of incident photons. Inhomogeneities are taken into account by attenuating the primary photon fluence exponentially utilizing the average total linear attenuation coefficient of intervening tissue, by multiplying photon fluence by the linear attenuation coefficient to yield the number of collisions in the scattering volume, and by scaling the path between the scattering volume element and the computation point by an effective density.

  2. Optical manifold

    DOEpatents

    Falicoff, Waqidi; Chaves, Julio C.; Minano, Juan Carlos; Benitez, Pablo; Dross, Oliver; Parkyn, Jr., William A.

    2010-02-23

    Optical systems are described that have at least one source of a beam of blue light with divergence under 15.degree.. A phosphor emits yellow light when excited by the blue light. A collimator is disposed with the phosphor and forms a yellow beam with divergence under 15.degree.. A dichroic filter is positioned to transmit the beam of blue light to the phosphor and to reflect the beam of yellow light to an exit aperture. In different embodiments, the beams of blue and yellow light are incident upon said filter with central angles of 15.degree., 22.degree., and 45.degree.. The filter may reflect all of one polarization and part of the other polarization, and a polarization rotating retroreflector may then be provided to return the unreflected light to the filter.

  3. Design of an epithermal column for BNCT based on D D fusion neutron facility

    NASA Astrophysics Data System (ADS)

    Durisi, E.; Zanini, A.; Manfredotti, C.; Palamara, F.; Sarotto, M.; Visca, L.; Nastasi, U.

    2007-05-01

    Boron Neutron Capture Therapy (BNCT) is currently performed on patients at nuclear reactors. At the same time the international BNCT community is engaged in the development of alternative facilities for in-hospital treatments. This paper investigates the potential of a novel high-output D-D neutron generator, developed at Lawrence Berkeley National Laboratory (CA, USA), for BNCT. The simulation code MCNP-4C is used to realize an accurate study of the epithermal column in view of the treatment of deep tumours. Different materials and Beam Shaping Assemblies (BSA) are investigated and an optimized configuration is proposed. The neutron beam quality is defined by the standard free beam parameters, calculated averaging over the collimator aperture. The results are discussed and compared with the performances of other facilities.

  4. SU-F-T-459: ArcCHECK Machine QA : Highly Efficient Quality Assurance Tool for VMAT, SRS & SBRT Linear Accelerator Delivery

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mhatre, V; Patwe, P; Dandekar, P

    Purpose: Quality assurance (QA) of complex linear accelerators is critical and highly time consuming. ArcCHECK Machine QA tool is used to test geometric and delivery aspects of linear accelerator. In this study we evaluated the performance of this tool. Methods: Machine QA feature allows user to perform quality assurance tests using ArcCHECK phantom. Following tests were performed 1) Gantry Speed 2) Gantry Rotation 3) Gantry Angle 4)MLC/Collimator QA 5)Beam Profile Flatness & Symmetry. Data was collected on trueBEAM stX machine for 6 MV for a period of one year. The Gantry QA test allows to view errors in gantry angle,more » rotation & assess how accurately the gantry moves around the isocentre. The MLC/Collimator QA tool is used to analyze & locate the differences between leaf bank & jaw position of linac. The flatness & Symmetry test quantifies beam flatness & symmetry in IEC-y & x direction. The Gantry & Flatness/Symmetry test can be performed for static & dynamic delivery. Results: The Gantry speed was 3.9 deg/sec with speed maximum deviation around 0.3 deg/sec. The Gantry Isocentre for arc delivery was 0.9mm & static delivery was 0.4mm. The maximum percent positive & negative difference was found to be 1.9 % & – 0.25 % & maximum distance positive & negative diff was 0.4mm & – 0.3 mm for MLC/Collimator QA. The Flatness for Arc delivery was 1.8 % & Symmetry for Y was 0.8 % & X was 1.8 %. The Flatness for gantry 0°,270°,90° & 180° was 1.75,1.9,1.8 & 1.6% respectively & Symmetry for X & Y was 0.8,0.6% for 0°, 0.6,0.7% for 270°, 0.6,1% for 90° & 0.6,0.7% for 180°. Conclusion: ArcCHECK Machine QA is an useful tool for QA of Modern linear accelerators as it tests both geometric & delivery aspects. This is very important for VMAT, SRS & SBRT treatments.« less

  5. The integral line-beam method for gamma skyshine analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shultis, J.K.; Faw, R.E.; Bassett, M.S.

    1991-03-01

    This paper presents a refinement of a simplified method, based on line-beam response functions, for performing skyshine calculations for shielded and collimated gamma-ray sources. New coefficients for an empirical fit to the line-beam response function are provided and a prescription for making the response function continuous in energy and emission direction is introduced. For a shielded source, exponential attenuation and a buildup factor correction for scattered photons in the shield are used. Results of the new integral line-beam method of calculation are compared to a variety of benchmark experimental data and calculations and are found to give generally excellent agreementmore » at a small fraction of the computational expense required by other skyshine methods.« less

  6. Fast collimated neutron flux measurement using stilbene scintillator and flashy analog-to-digital converter in JT-60U

    NASA Astrophysics Data System (ADS)

    Ishikawa, M.; Itoga, T.; Okuji, T.; Nakhostin, M.; Shinohara, K.; Hayashi, T.; Sukegawa, A.; Baba, M.; Nishitani, T.

    2006-10-01

    A line-integrated neutron emission profile is routinely measured using the radial neutron collimator system in JT-60U tokamak. Stilbene neuron detectors (SNDs), which combine a stilbene organic crystal scintillation detector (SD) with an analog neutron-gamma pulse shape discrimination (PSD) circuit, have been used to measure collimated neutron flux. Although the SND has many advantages as a neutron detector, the maximum count rate is limited up to ˜1×105counts/s due to the analog PSD circuit. To overcome this issue, a digital signal processing system (DSPS) using a flash analog-to-digital converter (Acqiris DC252, 8GHz, 10bits) has been developed at Cyclotron and Radioisotope Center in Tohoku University. In this system anode signals from photomultiplier of the SD are directory stored and digitized. Then, the PSD between neutrons and gamma rays is performed using software. The DSPS has been installed in the vertical neutron collimator system in JT-60U and applied to deuterium experiments. It is confirmed that the PSD is sufficiently performed and collimated neutron flux is successfully measured with count rate up to ˜5×105counts/s without the effect of pileup of detected pulses. The performance of the DSPS as a neutron detector, which supersedes the SND, is demonstrated.

  7. Technical Report: Evaluation of peripheral dose for flattening filter free photon beams.

    PubMed

    Covington, E L; Ritter, T A; Moran, J M; Owrangi, A M; Prisciandaro, J I

    2016-08-01

    To develop a comprehensive peripheral dose (PD) dataset for the two unflattened beams of nominal energy 6 and 10 MV for use in clinical care. Measurements were made in a 40 × 120 × 20 cm(3) (width × length × depth) stack of solid water using an ionization chamber at varying depths (dmax, 5, and 10 cm), field sizes (3 × 3 to 30 × 30 cm(2)), and distances from the field edge (5-40 cm). The effects of the multileaf collimator (MLC) and collimator rotation were also evaluated for a 10 × 10 cm(2) field. Using the same phantom geometry, the accuracy of the analytic anisotropic algorithm (AAA) and Acuros dose calculation algorithm was assessed and compared to the measured values. The PDs for both the 6 flattening filter free (FFF) and 10 FFF photon beams were found to decrease with increasing distance from the radiation field edge and the decreasing field size. The measured PD was observed to be higher for the 6 FFF than for the 10 FFF for all field sizes and depths. The impact of collimator rotation was not found to be clinically significant when used in conjunction with MLCs. AAA and Acuros algorithms both underestimated the PD with average errors of -13.6% and -7.8%, respectively, for all field sizes and depths at distances of 5 and 10 cm from the field edge, but the average error was found to increase to nearly -69% at greater distances. Given the known inaccuracies of peripheral dose calculations, this comprehensive dataset can be used to estimate the out-of-field dose to regions of interest such as organs at risk, electronic implantable devices, and a fetus. While the impact of collimator rotation was not found to significantly decrease PD when used in conjunction with MLCs, results are expected to be machine model and beam energy dependent. It is not recommended to use a treatment planning system to estimate PD due to the underestimation of the out-of-field dose and the inability to calculate dose at extended distances due to the limits of the dose calculation matrix.

  8. Evaluating the influence of laser wavelength and detection stage geometry on optical detection efficiency in a single-particle mass spectrometer

    NASA Astrophysics Data System (ADS)

    Marsden, Nicholas; Flynn, Michael J.; Taylor, Jonathan W.; Allan, James D.; Coe, Hugh

    2016-12-01

    Single-particle mass spectrometry (SPMS) is a useful tool for the online study of aerosols with the ability to measure size-resolved chemical composition with a temporal resolution relevant to atmospheric processes. In SPMS, optical particle detection is used for the effective temporal alignment of an ablation laser pulse with the presence of a particle in the ion source, and it gives the option of aerodynamic sizing by measuring the offset of particle arrival times between two detection stages. The efficiency of the optical detection stage has a strong influence on the overall instrument performance. A custom detection laser system consisting of a high-powered fibre-coupled Nd:YAG solid-state laser with a collimated beam was implemented in the detection stage of a laser ablation aerosol particle time-of-flight (LAAP-TOF) single-particle mass spectrometer without major modifications to instrument geometry. The use of a collimated laser beam permitted the construction of a numerical model that predicts the effects of detection laser wavelength, output power, beam focussing characteristics, light collection angle, particle size, and refractive index on the effective detection radius (R) of the detection laser beam. We compare the model predictions with an ambient data set acquired during the Ice in Clouds Experiment - Dust (ICE-D) project. The new laser system resulted in an order-of-magnitude improvement in instrument sensitivity to spherical particles in the size range 500-800 nm compared to a focussed 405 nm laser diode system. The model demonstrates that the limit of detection in terms of particle size is determined by the scattering cross section (Csca) as predicted by Mie theory. In addition, if light is collected over a narrow collection angle, oscillations in the magnitude of Csca with respect to particle diameter result in a variation in R, resulting in large particle-size-dependent variation in detection efficiency across the particle transmission range. This detection bias is imposed on the aerodynamic size distributions measured by the instrument and accounts for some of the detection bias towards sea salt particles in the ambient data set.

  9. Collider and Detector Protection at Beam Accidents

    NASA Astrophysics Data System (ADS)

    Rakhno, I. L.; Mokhov, N. V.; Drozhdin, A. I.

    2003-12-01

    Dealing with beam loss due to abort kicker prefire is considered for hadron colliders. The prefires occured at Tevatron (Fermilab) during Run I and Run II are analyzed and a protection system implemented is described. The effect of accidental beam loss in the Large Hadron Collider (LHC) at CERN on machine and detector components is studied via realistic Monte Carlo calculations. The simulations show that beam loss at an unsynchronized beam abort would result in severe heating of conventional and superconducting magnets and possible damage to the collider detector elements. A proposed set of collimators would reduce energy deposition effects to acceptable levels. Special attention is paid to reducing peak temperature rise within the septum magnet and minimizing quench region length downstream of the LHC beam abort straight section.

  10. Biconcave micro-optofluidic lens with low-refractive-index liquids.

    PubMed

    Song, Chaolong; Nguyen, Nam-Trung; Asundi, Anand Krishna; Low, Cassandra Lee-Ngo

    2009-12-01

    One of the current problems of micro-optofluidics is the choice of a suitable liquid with a high refractive index (RI). We report the use of a low-RI liquid in a biconcave liquid-core liquid-cladding lens for focusing light. For the characterization of the lens, a telescope system was constructed from polydimethylsiloxane lenses to collimate and expand a light beam emitted from an optical fiber. The tunable optofluidic biconcave lens focuses the parallel beam. Fluorescent dye diluted in an index-matching liquid was used for the visualization of the light rays in a beam-tracing chamber. The focused beam is tuned by adjusting the flow rate ratio between core and cladding streams.

  11. A jaw calibration method to provide a homogeneous dose distribution in the matching region when using a monoisocentric beam split technique.

    PubMed

    Cenizo, E; García-Pareja, S; Galán, P; Bodineau, C; Caudepón, F; Casado, F J

    2011-05-01

    Asymmetric collimators are currently available in most of linear accelerators. They involve a lot of clinical improvements, such as the monoisocentric beam split technique that is more and more used in many external radiotherapy treatments. The tolerance established for each independent jaw positioning is 1 mm. Within this tolerance, a gap or overlap of the collimators up to 2 mm can occur in the half beams matching region, causing dose heterogeneities up to 40%. In order to solve this dosimetric problem, we propose an accurate jaw calibration method based on the Monte Carlo modeling of linac photon beams. Simulating different jaw misalignments, the dose distribution occurring in the matching region for each particular configuration is precisely known, so we can relate the misalignment of the jaws with the maximum heterogeneity produced. From experimental measurements using film dosimetry, and taking into account Monte Carlo results, we obtain the actual misalignment of each jaw. By direct inspection of the readings of the potentiometers that control the position of the jaws, high precision correction can be performed, adjusting the obtained misalignments. In the linac studied, the dose heterogeneity in the junction performed with X jaws (those farther from the source), and 6 MV photon beam was initially over 12%, although each jaw was within the tolerance in position. After jaw calibration, the heterogeneity was reduced to below 3%. With this method, we are able to reduce the positioning accuracy to 0.2 mm. Consequently, the dose distribution in the junction of abutted fields is highly smoothed, achieving the maximum dose heterogeneity to be less than 3%.

  12. System, Apparatus and Method Employing a Dual Head Laser

    NASA Technical Reports Server (NTRS)

    Coyle, Donald B. (Inventor); Stysley, Paul R. (Inventor); Poulios, Demetrios (Inventor)

    2015-01-01

    A system, apparatus and method employing a laser with a split-head, V-assembly gain material configuration. Additionally, the present invention is directed to techniques to better dissipate or remove unwanted energies in laser operations. The present invention is also directed to techniques for better collimated laser beams, with single spatial mode quality (TEM00), with improved efficiency, in extreme environments, such as in outer space.

  13. Laser beam shaping for biomedical microscopy techniques

    NASA Astrophysics Data System (ADS)

    Laskin, Alexander; Kaiser, Peter; Laskin, Vadim; Ostrun, Aleksei

    2016-04-01

    Uniform illumination of a working field is very important in optical systems of confocal microscopy and various implementations of fluorescence microscopy like TIR, SSIM, STORM, PALM to enhance performance of these laser-based research techniques. Widely used TEM00 laser sources are characterized by essentially non-uniform Gaussian intensity profile which leads usually to non-uniform intensity distribution in a microscope working field or in a field of microlenses array of a confocal microscope optical system, this non-uniform illumination results in instability of measuring procedure and reducing precision of quantitative measurements. Therefore transformation of typical Gaussian distribution of a TEM00 laser to flat-top (top hat) profile is an actual technical task, it is solved by applying beam shaping optics. Due to high demands to optical image quality the mentioned techniques have specific requirements to a uniform laser beam: flatness of phase front and extended depth of field, - from this point of view the microscopy techniques are similar to holography and interferometry. There are different refractive and diffractive beam shaping approaches used in laser industrial and scientific applications, but only few of them are capable to fulfil the optimum conditions for beam quality required in discussed microscopy techniques. We suggest applying refractive field mapping beam shapers πShaper, which operational principle presumes almost lossless transformation of Gaussian to flat-top beam with flatness of output wavefront, conserving of beam consistency, providing collimated low divergent output beam, high transmittance, extended depth of field, negligible wave aberration, and achromatic design provides capability to work with several lasers with different wavelengths simultaneously. The main function of a beam shaper is transformation of laser intensity profile, further beam transformation to provide optimum for a particular technique spot size and shape has to be realized by an imaging optical system which can include microscope objectives and tube lenses. This paper will describe design basics of refractive beam shapers and optical layouts of their applying in microscopy systems. Examples of real implementations and experimental results will be presented as well.

  14. The journey from proton to gamma knife.

    PubMed

    Ganz, Jeremy C

    2014-01-01

    It was generally accepted by the early 1960s that proton beam radiosurgery was too complex and impractical. The need was seen for a new machine. The beam design had to be as good as a proton beam. It was also decided that a static design was preferable even if the evolution of that notion is no longer clear. Complex collimators were designed that using sources of cobalt-60 could produce beams with characteristics adequately close to those of proton beams. The geometry of the machine was determined including the distance of the sources from the patient the optimal distance between the sources. The first gamma unit was built with private money with no contribution from the Swedish state, which nonetheless required detailed design information in order to ensure radiation safety. This original machine was built with rectangular collimators to produce lesions for thalamotomy for functional work. However, with the introduction of dopamine analogs, this indication virtually disappeared overnight.

  15. Matching Electron Beams Without Secondary Collimation for Treatment of Extensive Recurrent Chest-Wall Carcinoma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Feygelman, Vladimir; Department of Physics, University of Manitoba, Winnipeg, MB; Mandelzweig, Yuri

    2015-01-15

    Matching electron beams without secondary collimators (applicators) were used for treatment of extensive, recurrent chest-wall carcinoma. Due to the wide penumbra of such beams, the homogeneity of the dose distribution at and around the junction point is clinically acceptable and relatively insensitive to positional errors. Specifically, dose around the junction point is homogeneous to within ±4% as calculated from beam profiles, while the positional error of 1 cm leaves this number essentially unchanged. The experimental isodose distribution in an anthropomorphic phantom supports this conclusion. Two electron beams with wide penumbra were used to cover the desired treatment area with satisfactorymore » dose homogeneity. The technique is relatively simple yet clinically useful and can be considered a viable alternative for treatment of extensive chest-wall disease. The steps are suggested to make this technique more universal.« less

  16. Defocusing beam line design for an irradiation facility at the TAEA SANAEM Proton Accelerator Facility

    NASA Astrophysics Data System (ADS)

    Gencer, A.; Demirköz, B.; Efthymiopoulos, I.; Yiğitoğlu, M.

    2016-07-01

    Electronic components must be tested to ensure reliable performance in high radiation environments such as Hi-Limu LHC and space. We propose a defocusing beam line to perform proton irradiation tests in Turkey. The Turkish Atomic Energy Authority SANAEM Proton Accelerator Facility was inaugurated in May 2012 for radioisotope production. The facility has also an R&D room for research purposes. The accelerator produces protons with 30 MeV kinetic energy and the beam current is variable between 10 μA and 1.2 mA. The beam kinetic energy is suitable for irradiation tests, however the beam current is high and therefore the flux must be lowered. We plan to build a defocusing beam line (DBL) in order to enlarge the beam size, reduce the flux to match the required specifications for the irradiation tests. Current design includes the beam transport and the final focusing magnets to blow up the beam. Scattering foils and a collimator is placed for the reduction of the beam flux. The DBL is designed to provide fluxes between 107 p /cm2 / s and 109 p /cm2 / s for performing irradiation tests in an area of 15.4 cm × 21.5 cm. The facility will be the first irradiation facility of its kind in Turkey.

  17. Influence of beam incidence and irradiation parameters on stray neutron doses to healthy organs of pediatric patients treated for an intracranial tumor with passive scattering proton therapy.

    PubMed

    Bonfrate, A; Farah, J; De Marzi, L; Delacroix, S; Hérault, J; Sayah, R; Lee, C; Bolch, W E; Clairand, I

    2016-04-01

    In scattering proton therapy, the beam incidence, i.e. the patient's orientation with respect to the beam axis, can significantly influence stray neutron doses although it is almost not documented in the literature. MCNPX calculations were carried out to estimate stray neutron doses to 25 healthy organs of a 10-year-old female phantom treated for an intracranial tumor. Two beam incidences were considered in this article, namely a superior (SUP) field and a right lateral (RLAT) field. For both fields, a parametric study was performed varying proton beam energy, modulation width, collimator aperture and thickness, compensator thickness and air gap size. Using a standard beam line configuration for a craniopharyngioma treatment, neutron absorbed doses per therapeutic dose of 63μGyGy(-1) and 149μGyGy(-1) were found at the heart for the SUP and the RLAT fields, respectively. This dose discrepancy was explained by the different patient's orientations leading to changes in the distance between organs and the final collimator where external neutrons are mainly produced. Moreover, investigations on neutron spectral fluence at the heart showed that the number of neutrons was 2.5times higher for the RLAT field compared against the SUP field. Finally, the influence of some irradiation parameters on neutron doses was found to be different according to the beam incidence. Beam incidence was thus found to induce large variations in stray neutron doses, proving that this parameter could be optimized to enhance the radiation protection of the patient. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  18. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Electron beam deflection, focusing, and collimation by a femtosecond laser lens

    NASA Astrophysics Data System (ADS)

    Minogin, V. G.

    2009-11-01

    This work examines spatial separation of femtosecond electron bunches using the ponderomotive potential created by femtosecond laser pulses. It is shown that ponderomotive optical potentials are capable of effectively deflecting, focusing, and collimating narrow femtosecond electron bunches.

  19. The Magsat three axis arc second precision attitude transfer system

    NASA Technical Reports Server (NTRS)

    Schenkel, F. W.; Heins, R. J.

    1981-01-01

    The Magsat Attitude Transfer System (ATS), which provides attitude alteration in pitch, yaw, and roll is described. A remote vector magnetometer extends from Magsat on a 20 ft boom, requiring vector orientation by reference to coordinate axes determined by a set of star mapping cameras. The ATS was designed to perform in a solar illuminated environment by using an optically narrow bandwidth with synchronous demodulation at 9300 A. The pitch/yaw optical design, the electrooptics, and signal and switching diagrams are provided. Simple mirrors with no moving parts are placed on the magnetometer to reflect a collimated beam from the ATS for attitude indication, which is accurate to one part in 96. Alignment was completed within 24 hr after launch.

  20. Optical fiber systems for the BigBOSS instrument

    NASA Astrophysics Data System (ADS)

    Edelstein, Jerry; Poppett, Claire; Sirk, Martin; Besuner, Robert; Lafever, Robin; Allington-Smith, Jeremy R.; Murray, Graham J.

    2012-09-01

    We describe the fiber optics systems for use in BigBOSS, a proposed massively parallel multi-object spectrograph for the Kitt Peak Mayall 4-m telescope that will measure baryon acoustic oscillations to explore dark energy. BigBOSS will include 5,000 optical fibers each precisely actuator-positioned to collect an astronomical target’s flux at the telescope prime-focus. The fibers are to be routed 40m through the telescope facility to feed ten visible-band imaging spectrographs. We report on our fiber component development and performance measurement program. Results include the numerical modeling of focal ratio degradation (FRD), observations of actual fibers’ collimated and converging beam FRD, and observations of FRD from different types of fiber terminations, mechanical connectors, and fusion-splice connections.

  1. Linac head scatter factor for asymmetric radiation field

    NASA Astrophysics Data System (ADS)

    Soubra, Mazen Ahmed

    1997-11-01

    The head scatter factor, Sh is an important dosimetric quantity used in radiation therapy dose calculation. It is empirically determined and its field size dependence reflects changes in photon scatter from components in the linac treatment head. In this work a detailed study of the physical factors influencing the determination of Sh was performed with particular attention given to asymmetric field geometries. Ionization measurements for 6 and 18 MV photon beams were made to examine the factors which determine Sh. These include: phantom size and material, collimator backscatter, non-lateral electronic equilibrium (LEE) conditions, electron contamination, collimator-exchange, photon energy, flattening filter and off-axis distance (OAD). Results indicated that LEE is not required for Sh measurements if electron contamination is minimized. Brass caps or polystyrene miniphantoms can both be used in Sh measurements provided the phantom thickness is large enough to stop contaminant electrons. Backscatter radiation effects into the monitor chamber were found to be negligible for the Siemens linac. It was found that the presence and shape of the flattening filter had a significant effect on the empirically determined value of Sh was also shown to be a function of OAD, particularly for small fields. For fields larger than 12×12 cm2/ Sh was independent of OAD. A flattening filter mass model was introduced to explain qualitatively the above results. A detailed Monte Carlo simulation of the Siemens KD2 linac head in 6 MV mode was performed to investigate the sources of head scatter which contribute to the measured Sh. The simulated head components include the flattening filter, the electron beam stopper, the primary collimator, the photon monitor chamber and the secondary collimators. The simulations showed that the scatter from the head of the Siemens linac is a complex function of the head components. On the central axis the flattening filter played the dominant role in the contributing to scatter. However this role was significantly reduced off- axis and other head components, such as the electron beam stopper and the primary collimator, became more important. The role of the mirror and ion chamber was relatively minor. Scatter from the secondary collimators was shown to be a function of the filed size and the position of the collimators in the treatment head. They were also found to play a dual role, both as a scatter source and as an attenuator for scatter produced upstream in the linac head. A closed form model, based on the work of Yu and Slobada, was developed to estimate head scatter factors for on- and off-axis asymmetric fields. The model requires three parameters to fit the measured data. The first, a constant c, has a physical significance and is independent of energy and off-axis distance. The second, g, shows a small variation with the energy and OAD while the third parameter, the primary-to-scatter ratio, is strongly dependent on energy and off-axis distance. Comparison of Sh, predicted by the model, to measurement for a large range of symmetric and asymmetric fields showed excellent agreement. A maximum of 0.7% discrepancy was observed at 12 cm OAD.

  2. Electron cyclotron resonance ion source plasma characterization by X-ray spectroscopy and X-ray imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mascali, David, E-mail: davidmascali@lns.infn.it; Castro, Giuseppe; Celona, Luigi

    2016-02-15

    An experimental campaign aiming to investigate electron cyclotron resonance (ECR) plasma X-ray emission has been recently carried out at the ECRISs—Electron Cyclotron Resonance Ion Sources laboratory of Atomki based on a collaboration between the Debrecen and Catania ECR teams. In a first series, the X-ray spectroscopy was performed through silicon drift detectors and high purity germanium detectors, characterizing the volumetric plasma emission. The on-purpose developed collimation system was suitable for direct plasma density evaluation, performed “on-line” during beam extraction and charge state distribution characterization. A campaign for correlating the plasma density and temperature with the output charge states and themore » beam intensity for different pumping wave frequencies, different magnetic field profiles, and single-gas/gas-mixing configurations was carried out. The results reveal a surprisingly very good agreement between warm-electron density fluctuations, output beam currents, and the calculated electromagnetic modal density of the plasma chamber. A charge-coupled device camera coupled to a small pin-hole allowing X-ray imaging was installed and numerous X-ray photos were taken in order to study the peculiarities of the ECRIS plasma structure.« less

  3. Exploring Astrophysical Magnetohydrodynamics in the Laboratory

    NASA Astrophysics Data System (ADS)

    Manuel, Mario

    2014-10-01

    Plasma evolution in many astrophysical systems is dominated by magnetohydrodynamics. Specifically of interest to this talk are collimated outflows from accretion systems. Away from the central object, the Euler equations can represent the plasma dynamics well and may be scaled to a laboratory system. We have performed experiments to investigate the effects of a background magnetic field on an otherwise hydrodynamically collimated plasma. Laser-irradiated, cone targets produce hydrodynamically collimated plasma jets and a pulse-powered solenoid provides a constant background magnetic field. The application of this field is shown to completely disrupt the original flow and a new magnetically-collimated, hollow envelope is produced. Results from these experiments and potential implications for their astrophysical analogs will be discussed.

  4. 21 CFR 892.1610 - Diagnostic x-ray beam-limiting device.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Diagnostic x-ray beam-limiting device. 892.1610... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1610 Diagnostic x-ray beam-limiting device. (a) Identification. A diagnostic x-ray beam-limiting device is a device such as a collimator, a...

  5. 21 CFR 892.1610 - Diagnostic x-ray beam-limiting device.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Diagnostic x-ray beam-limiting device. 892.1610... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1610 Diagnostic x-ray beam-limiting device. (a) Identification. A diagnostic x-ray beam-limiting device is a device such as a collimator, a...

  6. 21 CFR 892.1610 - Diagnostic x-ray beam-limiting device.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Diagnostic x-ray beam-limiting device. 892.1610... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1610 Diagnostic x-ray beam-limiting device. (a) Identification. A diagnostic x-ray beam-limiting device is a device such as a collimator, a...

  7. 21 CFR 892.1610 - Diagnostic x-ray beam-limiting device.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Diagnostic x-ray beam-limiting device. 892.1610... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1610 Diagnostic x-ray beam-limiting device. (a) Identification. A diagnostic x-ray beam-limiting device is a device such as a collimator, a...

  8. 21 CFR 892.1610 - Diagnostic x-ray beam-limiting device.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Diagnostic x-ray beam-limiting device. 892.1610... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1610 Diagnostic x-ray beam-limiting device. (a) Identification. A diagnostic x-ray beam-limiting device is a device such as a collimator, a...

  9. Ion source with improved primary arc collimation

    DOEpatents

    Dagenhart, W.K.

    1983-12-16

    An improved negative ion source is provided in which a self-biasing, molybdenum collimator is used to define the primary electron stream arc discharge from a filament operated at a negative potential. The collimator is located between the anode and the filament. It is electrically connected to the anode by means of an appropriate size resistor such that the collimator is biased at essentially the filament voltage during operation. Initially, the full arc voltage appears across the filament to collimator until the arc discharge strikes. Then the collimator biases itself to essentially filament potential due to current flow through the resistor thus defining the primary electron stream without intercepting any appreciable arc power. The collimator aperture is slightly smaller than the anode aperture to shield the anode from the arc power which, in the past, has caused overheating and erosion of the anode collimator during extended time pulsed-beam operation of the source. With the self-biasing collimator of this invention, the ion source may be operated from short pulse periods to steady-state without destroying the anode.

  10. Ion source with improved primary arc collimation

    DOEpatents

    Dagenhart, William K.

    1985-01-01

    An improved negative ion source is provided in which a self-biasing, molybdenum collimator is used to define the primary electron stream arc discharge from a filament operated at a negative potential. The collimator is located between the anode and the filament. It is electrically connected to the anode by means of an appropriate size resistor such that the collimator is biased at essentially the filament voltage during operation. Initially, the full arc voltage appears across the filament to collimator until the arc discharge strikes. Then the collimator biases itself to essentially filament potential due to current flow through the resistor thus defining the primary electron stream without intercepting any appreciable arc power. The collimator aperture is slightly smaller than the anode aperture to shield the anode from the arc power, thereby preventing the exposure of the anode to the full arc power which, in the past, has caused overheating and erosion of the anode collimator during extended time pulsed-beam operation of the source. With the self-biasing collimator of this invention, the ion source may be operated from short pulse periods to steady-state without destroying the anode.

  11. Laser-induced retinal injury studies with wavefront correction

    NASA Astrophysics Data System (ADS)

    Lund, Brian J.; Lund, David J.; Edsall, Peter R.

    2007-02-01

    The ability of a laser beam to damage the retina of the eye depends on the accuracy to which the optics of the eye focuses the beam onto the retina. Data acquired through retinal injury threshold studies indicate that the focus achieved by the eye of an anesthetized non-human primate (NHP) is worse than theoretical predictions, and therefore the measured injury threshold will decrease with decreasing retinal irradiance area until the beam diameter at the retina is less than 10 μm. However, a number of investigations over a range of wavelengths and exposure durations show that the incident energy required to produce a retinal injury in a NHP eye does not decrease for retinal irradiance diameters smaller than ~100 μm, but reaches a minimum at that diameter and remains nearly constant for smaller diameters. A possible explanation is that uncompensated aberrations of the eye of the anesthetized NHP are larger than predicted. Focus is a dynamic process which is purposely defeated while performing measurements of retinal injury thresholds. Optical wavefront correction systems have become available which have the capability to compensate for ocular aberrations. This paper will report on an injury threshold experiment which incorporates an adaptive optics system to compensate for the aberrations of a NHP eye during exposure to a collimated laser beam, therefore producing a near diffraction limited beam spot on the retina.

  12. Analysis of the kinestatic charge detection system as a high detective quantum efficiency electronic portal imaging device.

    PubMed

    Samant, Sanjiv S; Gopal, Arun

    2006-09-01

    Megavoltage x-ray imaging suffers from reduced image quality due to low differential x-ray attenuation and large Compton scatter compared with kilovoltage imaging. Notwithstanding this, electronic portal imaging devices (EPIDs) are now widely used in portal verification in radiotherapy as they offer significant advantages over film, including immediate digital imaging and superior contrast range. However video-camera-based EPIDs (VEPIDs) are limited by problems of low light collection efficiency and significant light scatter, leading to reduced contrast and spatial resolution. Indirect and direct detection-based flat-panel EPIDs have been developed to overcome these limitations. While flat-panel image quality has been reported to exceed that achieved with portal film, these systems have detective quantum efficiency (DQE) limited by the thin detection medium and are sensitive to radiation damage to peripheral read-out electronics. An alternative technology for high-quality portal imaging is presented here: kinesatic charge detection (KCD). The KCD is a scanning tri-electrode ion-chamber containing high-pressure noble gas (xenon at 100 atm) used in conjunction with a strip-collimated photon beam. The chamber is scanned across the patient, and an external electric field is used to regulate the cation drift velocity. By matching the scanning velocity with that of the cation (i.e., ion) drift velocity, the cations remain static in the object frame of reference, allowing temporal integration of the signal. The KCD offers several advantages as a portal imaging system. It has a thick detector geometry with an active detection depth of 6.1 cm, compared to the sub-millimeter thickness of the phosphor layer in conventional phosphor screens, leading to an order of magnitude advantage in quantum efficiency (>0.3). The unique principle of and the use of the scanning strip-collimated x-ray beam provide further integration of charges in time, reduced scatter, and a significantly reduced imaging dose, enhancing the imaging signal-to-noise ratio (SNR) and leading to high DQE. While thick detectors usually suffer from reduced spatial resolution, the KCD provides good spatial resolution due to high gas pressure that limits the spread of scattered electrons, and a strip-collimated beam that significantly reduces the inclusion of scatter in the imaging signal. A 10 cm wide small-field-of-view (SFOV) prototype of the KCD is presented with a complete analysis of its imaging performance. Measurements of modulation transfer function (MTF), noise power spectrum (NPS), and DQE were in good agreement with Monte Carlo simulations. Imaging signal loss from recombination within the KCD chamber was measured at different gas pressures, ion drift velocities, and strip-collimation widths. Image quality for the prototype KCD was also observed with anthropomorphic phantom imaging in comparison with various commercial and research portal imaging systems, including VEPID, flat-panel imager, and conventional and high contrast film systems. KCD-based imaging provided very good contrast and good spatial resolution at very low imaging dose (0.1 cGy per image). For the prototype KCD, measurements yielded DQE(0)=0.19 and DQE(1 cy/mm)=0.004.

  13. Design and performance evaluation of a 20-aperture multipinhole collimator for myocardial perfusion imaging applications.

    PubMed

    Bowen, Jason D; Huang, Qiu; Ellin, Justin R; Lee, Tzu-Cheng; Shrestha, Uttam; Gullberg, Grant T; Seo, Youngho

    2013-10-21

    Single photon emission computed tomography (SPECT) myocardial perfusion imaging remains a critical tool in the diagnosis of coronary artery disease. However, after more than three decades of use, photon detection efficiency remains poor and unchanged. This is due to the continued reliance on parallel-hole collimators first introduced in 1964. These collimators possess poor geometric efficiency. Here we present the performance evaluation results of a newly designed multipinhole collimator with 20 pinhole apertures (PH20) for commercial SPECT systems. Computer simulations and numerical observer studies were used to assess the noise, bias and diagnostic imaging performance of a PH20 collimator in comparison with those of a low energy high resolution (LEHR) parallel-hole collimator. Ray-driven projector/backprojector pairs were used to model SPECT imaging acquisitions, including simulation of noiseless projection data and performing MLEM/OSEM image reconstructions. Poisson noise was added to noiseless projections for realistic projection data. Noise and bias performance were investigated for five mathematical cardiac and torso (MCAT) phantom anatomies imaged at two gantry orbit positions (19.5 and 25.0 cm). PH20 and LEHR images were reconstructed with 300 MLEM iterations and 30 OSEM iterations (ten subsets), respectively. Diagnostic imaging performance was assessed by a receiver operating characteristic (ROC) analysis performed on a single MCAT phantom; however, in this case PH20 images were reconstructed with 75 pixel-based OSEM iterations (four subsets). Four PH20 projection views from two positions of a dual-head camera acquisition and 60 LEHR projections were simulated for all studies. At uniformly-imposed resolution of 12.5 mm, significant improvements in SNR and diagnostic sensitivity (represented by the area under the ROC curve, or AUC) were realized when PH20 collimators are substituted for LEHR parallel-hole collimators. SNR improves by factors of 1.94-2.34 for the five patient anatomies and two orbital positions studied. For the ROC analysis the PH20 AUC is larger than the LEHR AUC with a p-value of 0.0067. Bias performance, however, decreases with the use of PH20 collimators. Systematic analyses showed PH20 collimators present improved diagnostic imaging performance over LEHR collimators, requiring only collimator exchange on existing SPECT cameras for their use.

  14. Design and performance evaluation of a 20-aperture multipinhole collimator for myocardial perfusion imaging applications

    NASA Astrophysics Data System (ADS)

    Bowen, Jason D.; Huang, Qiu; Ellin, Justin R.; Lee, Tzu-Cheng; Shrestha, Uttam; Gullberg, Grant T.; Seo, Youngho

    2013-10-01

    Single photon emission computed tomography (SPECT) myocardial perfusion imaging remains a critical tool in the diagnosis of coronary artery disease. However, after more than three decades of use, photon detection efficiency remains poor and unchanged. This is due to the continued reliance on parallel-hole collimators first introduced in 1964. These collimators possess poor geometric efficiency. Here we present the performance evaluation results of a newly designed multipinhole collimator with 20 pinhole apertures (PH20) for commercial SPECT systems. Computer simulations and numerical observer studies were used to assess the noise, bias and diagnostic imaging performance of a PH20 collimator in comparison with those of a low energy high resolution (LEHR) parallel-hole collimator. Ray-driven projector/backprojector pairs were used to model SPECT imaging acquisitions, including simulation of noiseless projection data and performing MLEM/OSEM image reconstructions. Poisson noise was added to noiseless projections for realistic projection data. Noise and bias performance were investigated for five mathematical cardiac and torso (MCAT) phantom anatomies imaged at two gantry orbit positions (19.5 and 25.0 cm). PH20 and LEHR images were reconstructed with 300 MLEM iterations and 30 OSEM iterations (ten subsets), respectively. Diagnostic imaging performance was assessed by a receiver operating characteristic (ROC) analysis performed on a single MCAT phantom; however, in this case PH20 images were reconstructed with 75 pixel-based OSEM iterations (four subsets). Four PH20 projection views from two positions of a dual-head camera acquisition and 60 LEHR projections were simulated for all studies. At uniformly-imposed resolution of 12.5 mm, significant improvements in SNR and diagnostic sensitivity (represented by the area under the ROC curve, or AUC) were realized when PH20 collimators are substituted for LEHR parallel-hole collimators. SNR improves by factors of 1.94-2.34 for the five patient anatomies and two orbital positions studied. For the ROC analysis the PH20 AUC is larger than the LEHR AUC with a p-value of 0.0067. Bias performance, however, decreases with the use of PH20 collimators. Systematic analyses showed PH20 collimators present improved diagnostic imaging performance over LEHR collimators, requiring only collimator exchange on existing SPECT cameras for their use.

  15. Comparison of three methods reducing the beam parameter product of a laser diode stack for long range laser illumination applications

    NASA Astrophysics Data System (ADS)

    Lutz, Yves; Poyet, Jean-Michel; Metzger, Nicolas

    2013-10-01

    Laser diode stacks are interesting laser sources for active imaging illuminators. They allow the accumulation of large amounts of energy in multi-pulse mode, which is well suited for long-range image recording. Even when laser diode stacks are equipped with fast-axis collimation (FAC) and slow-axis collimation (SAC) microlenses, their beam parameter product (BPP) are not compatible with a direct use in highly efficient and compact illuminators. This is particularly true when narrow divergences are required such as for long range applications. To overcome these difficulties, we conducted investigations in three different ways. A first near infrared illuminator based on the use of conductively cooled mini-bars was designed, realized and successfully tested during outdoor experimentations. This custom specified stack was then replaced in a second step by an off-the-shelf FAC + SAC micro lensed stack where the brightness was increased by polarization overlapping. The third method still based on a commercial laser diode stack uses a non imaging optical shaping principle resulting in a virtually restacked laser source with enhanced beam parameters. This low cost, efficient and low alignment sensitivity beam shaping method allows obtaining a compact and high performance laser diode illuminator for long range active imaging applications. The three methods are presented and compared in this paper.

  16. An accelerator-based neutron microbeam system for studies of radiation effects

    PubMed Central

    Xu, Yanping; Randers-Pehrson, Gerhard; Marino, Stephen A.; Bigelow, Alan W.; Akselrod, Mark S.; Sykora, Jeff G.; Brenner, David J.

    2011-01-01

    A novel neutron microbeam is being developed at the Radiological Research Accelerator Facility (RARAF) of Columbia University. The RARAF microbeam facility has been used for studies of radiation bystander effects in mammalian cells for many years. Now a prototype neutron microbeam is being developed that can be used for bystander effect studies. The neutron microbeam design here is based on the existing charged particle microbeam technology at the RARAF. The principle of the neutron microbeam is to use the proton beam with a micrometre-sized diameter impinging on a very thin lithium fluoride target system. From the kinematics of the 7Li(p,n)7Be reaction near the threshold of 1.881 MeV, the neutron beam is confined within a narrow, forward solid angle. Calculations show that the neutron spot using a target with a 17-µm thick gold backing foil will be <20 µm in diameter for cells attached to a 3.8-µm thick propylene-bottomed cell dish in contact with the target backing. The neutron flux will roughly be 2000 per second based on the current beam setup at the RARAF singleton accelerator. The dose rate will be about 200 mGy min−1. The principle of this neutron microbeam system has been preliminarily tested at the RARAF using a collimated proton beam. The imaging of the neutron beam was performed using novel fluorescent nuclear track detector technology based on Mg-doped luminescent aluminum oxide single crystals and confocal laser scanning fluorescent microscopy. PMID:21131327

  17. The Use of an Electron Microchannel as a Self-Extracting and Focusing Plasma Cathode Electron Gun

    NASA Astrophysics Data System (ADS)

    Cornish, S.; Khachan, J.

    2016-02-01

    A new and simple type of electron gun is presented. Unlike conventional electron guns, which require a heated filament or extractor, accelerator and focusing electrodes, this gun uses the collimated electron microchannels of an inertial electrostatic confinement (IEC) discharge to achieve the same outcome. A cylindrical cathode is placed coaxially within a cylindrical anode to create the discharge. Collimated beams of electrons and fast neutrals emerge along the axis of the cylindrical cathode. This geometry isolates one of the microchannels that emerge in a negatively biased IEC grid. The internal operating pressure range of the gun is 35-190 mTorr. A small aperture separates the gun from the main vacuum chamber in order to achieve a pressure differential. The chamber was operated at pressures of 4-12 mTorr. The measured current produced by the gun was 0.1-3 mA (0.2-14 mA corrected measurement) for discharge currents of 1-45 mA and discharge voltages of 0.5-12 kV. The collimated electron beam emerges from the aperture into the vacuum chamber. The performance of the gun is unaffected by the pressure differential between the vacuum chamber and the gun. This allows the aperture to be removed and the chamber pressure to be equal to the gun pressure if required.

  18. Achromatic self-referencing interferometer

    DOEpatents

    Feldman, Mark

    1994-01-01

    A self-referencing Mach-Zehnder interferometer for accurately measuring laser wavefronts over a broad wavelength range (for example, 600 nm to 900 nm). The apparatus directs a reference portion of an input beam to a reference arm and a measurement portion of the input beam to a measurement arm, recombines the output beams from the reference and measurement arms, and registers the resulting interference pattern ("first" interferogram) at a first detector. Optionally, subportions of the measurement portion are diverted to second and third detectors, which respectively register intensity and interferogram signals which can be processed to reduce the first interferogram's sensitivity to input noise. The reference arm includes a spatial filter producing a high quality spherical beam from the reference portion, a tilted wedge plate compensating for off-axis aberrations in the spatial filter output, and mirror collimating the radiation transmitted through the tilted wedge plate. The apparatus includes a thermally and mechanically stable baseplate which supports all reference arm optics, or at least the spatial filter, tilted wedge plate, and the collimator. The tilted wedge plate is mounted adjustably with respect to the spatial filter and collimator, so that it can be maintained in an orientation in which it does not introduce significant wave front errors into the beam propagating through the reference arm. The apparatus is polarization insensitive and has an equal path length configuration enabling measurement of radiation from broadband as well as closely spaced laser line sources.

  19. Improved self-reliance shearing interferometric technique for collimation testing

    NASA Astrophysics Data System (ADS)

    Zhao, Mingshan; Li, Guohua; Wang, Zhaobing; Jing, Yaling; Li, Yi

    1995-06-01

    Self-reference single plate shearing interferometric technique used for collimation testing of light beams are briefly reviewed. Two improved configurations of this self-reference interferometry with an inclined screen and matched half-field interferograms are described in detail. Sensitivity of these configurations is analyzed and compared with that of the existing ones.

  20. Beam collimation and focusing and error analysis of LD and fiber coupling system based on ZEMAX

    NASA Astrophysics Data System (ADS)

    Qiao, Lvlin; Zhou, Dejian; Xiao, Lei

    2017-10-01

    Laser diodde has many advantages, such as high efficiency, small volume, low cost and easy integration, so it is widely used. Because of its poor beam quality, the application of semiconductor laser has also been seriously hampered. In view of the poor beam quality, the ZEMAX optical design software is used to simulate the far field characteristics of the semiconductor laser beam, and the coupling module of the semiconductor laser and the optical fiber is designed and optimized. And the beam is coupled into the fiber core diameter d=200µm, the numerical aperture NA=0.22 optical fiber, the output power can reach 95%. Finally, the influence of the three docking errors on the coupling efficiency during the installation process is analyzed.

  1. Motion-Base Simulator Evaluation of an Aircraft Using an External Vision System

    NASA Technical Reports Server (NTRS)

    Kramer, Lynda J.; Williams, Steven P.; Arthur, J. J.; Rehfeld, Sherri A.; Harrison, Stephanie

    2012-01-01

    Twelve air transport-rated pilots participated as subjects in a motion-base simulation experiment to evaluate the use of eXternal Vision Systems (XVS) as enabling technologies for future supersonic aircraft without forward facing windows. Three head-up flight display concepts were evaluated -a monochromatic, collimated Head-up Display (HUD) and a color, non-collimated XVS display with a field-of-view (FOV) equal to and also, one significantly larger than the collimated HUD. Approach, landing, departure, and surface operations were conducted. Additionally, the apparent angle-of-attack (AOA) was varied (high/low) to investigate the vertical field-of-view display requirements and peripheral, side window visibility was experimentally varied. The data showed that lateral approach tracking performance and lateral landing position were excellent regardless of AOA, display FOV, display collimation or whether peripheral cues were present. However, the data showed glide slope approach tracking appears to be affected by display size (i.e., FOV) and collimation. The monochrome, collimated HUD and color, uncollimated XVS with Full FOV display had (statistically equivalent) glide path performance improvements over the XVS with HUD FOV display. Approach path performance results indicated that collimation may not be a requirement for an XVS display if the XVS display is large enough and employs color. Subjective assessments of mental workload and situation awareness also indicated that an uncollimated XVS display may be feasible. Motion cueing appears to have improved localizer tracking and touchdown sink rate across all displays.

  2. "Characterization of ELEKTA SRS cone collimator using high spatial resolution monolithic silicon detector array".

    PubMed

    Shukaili, Khalsa Al; Corde, Stéphanie; Petasecca, Marco; Pereveratylo, Vladimir; Lerch, Michael; Jackson, Michael; Rosenfeld, Anatoly

    2018-05-22

    To investigate the accuracy of the dosimetry of radiation fields produced by small ELEKTA cone collimators used for stereotactic radiosurgery treatments (SRS) using commercially available detectors EBT3 Gafchromic TM film, IBA Stereotactic diode (SFD), and the recently developed detector DUO, which is a monolithic silicon orthogonal linear diode array detector. These three detectors were used for the measurement of beam profiles, output factors, and percentage depth dose for SRS cone collimators with cone sizes ranging from 5 to 50 mm diameter. The measurements were performed at 10 cm depth and 90 cm SSD. The SRS cone beam profiles measured with DUO, EBT3 film, and IBA SFD agreed well, results being in agreement within ±0.5 mm in the FWHM, and ±0.7 mm in the penumbra region. The output factor measured by DUO with 0.5 mm air gap above agrees within ±1% with EBT3. The OF measured by IBA SFD (corrected for the over-response) agreed with both EBT3 and DUO within ±2%. All three detectors agree within ±2% for PDD measurements for all SRS cones. The characteristics of the ELEKTA SRS cone collimator have been evaluated by using a monolithic silicon high spatial resolution detector DUO, EBT3, and IBA SFD diode. The DUO detector is suitable for fast real-time quality assurance dosimetry in small radiation fields typical for SRS/SRT. This has been demonstrated by its good agreement of measured doses with EBT 3 films. © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

  3. SU-F-T-670: From the OR to the Radiobiology Lab: The Journey of a Small X-Ray Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lehmann, J; The University of Sydney, Sydney, NSW; The University of Newcastle, Newcastle, NSW

    Purpose: Irradiation of small animal tumor models within laboratories is vital to radiobiological experiments. Often the animals are not able to be brought back into the lab after being taken out for irradiation. Cell biology laboratories benefit from irradiation capability available around the clock without regard to patient load in an associated radiotherapy clinic. Commercial systems are available, but bulky and expensive. Methods: An intraoperative kV irradiation system (IntraBeam™) designed to deliver spherical dose distributions to surgical cavities has been repurposed for the irradiation of cell plates and small laboratory animals. An applicator has been altered to allow for simple,more » open fields. Special collimators are being developed. BEAMnrc Monte Carlo simulations with the “NRC swept BEAM” source model have been performed to characterize the dose distributions, to develop optimal collimators and as basis for dose prescription. Measurements with radiochromic film and with an ionization chamber were performed to characterize the beam and to validate the simulations. Results: Using its highest setting (50 kV and 40 µA) the x-ray unit is capable of delivering dose rates over 1 Gy/min homogeneously to standard cell plates even without an optimized collimator. Smaller areas (tumors in animals) can be irradiated with significantly higher dose rates (> 20 Gy/min) depending on distance of the source to the tumor. The HVL was found to be 0.21 mm Al which means the shielding requirements for the device are easily achievable in the lab. Conclusion: A mobile irradiation facility is feasible. It will allow easier access to radiation for radiobiology experiments. The modified system is versatile in that for cell plates homogenous irradiations can be achieved through distance from the source, while for high dose rate small field irradiations the source can be brought in close proximity to the target.« less

  4. Technical Note: A treatment plan comparison between dynamic collimation and a fixed aperture during spot scanning proton therapy for brain treatment

    PubMed Central

    Smith, Blake; Gelover, Edgar; Moignier, Alexandra; Wang, Dongxu; Flynn, Ryan T.; Lin, Liyong; Kirk, Maura; Solberg, Tim; Hyer, Daniel E.

    2016-01-01

    Purpose: To quantitatively assess the advantages of energy-layer specific dynamic collimation system (DCS) versus a per-field fixed aperture for spot scanning proton therapy (SSPT). Methods: Five brain cancer patients previously planned and treated with SSPT were replanned using an in-house treatment planning system capable of modeling collimated and uncollimated proton beamlets. The uncollimated plans, which served as a baseline for comparison, reproduced the target coverage and organ-at-risk sparing of the clinically delivered plans. The collimator opening for the fixed aperture-based plans was determined from the combined cross sections of the target in the beam’s eye view over all energy layers which included an additional margin equivalent to the maximum beamlet displacement for the respective energy of that energy layer. The DCS-based plans were created by selecting appropriate collimator positions for each row of beam spots during a Raster-style scanning pattern which were optimized to maximize the dose contributions to the target and limited the dose delivered to adjacent normal tissue. Results: The reduction of mean dose to normal tissue adjacent to the target, as defined by a 10 mm ring surrounding the target, averaged 13.65% (range: 11.8%–16.9%) and 5.18% (2.9%–7.1%) for the DCS and fixed aperture plans, respectively. The conformity index, as defined by the ratio of the volume of the 50% isodose line to the target volume, yielded an average improvement of 21.35% (19.4%–22.6%) and 8.38% (4.7%–12.0%) for the DCS and fixed aperture plans, respectively. Conclusions: The ability of the DCS to provide collimation to each energy layer yielded better conformity in comparison to fixed aperture plans. PMID:27487886

  5. Physical and engineering aspect of carbon beam therapy

    NASA Astrophysics Data System (ADS)

    Kanai, Tatsuaki; Kanematsu, Nobuyuki; Minohara, Shinichi; Yusa, Ken; Urakabe, Eriko; Mizuno, Hideyuki; Iseki, Yasushi; Kanazawa, Mitsutaka; Kitagawa, Atsushi; Tomitani, Takehiro

    2003-08-01

    Conformal irradiation system of HIMAC has been up-graded for a clinical trial using a technique of a layer-stacking method. The system has been developed for localizing irradiation dose to target volume more effectively than the present irradiation dose. With dynamic control of the beam modifying devices, a pair of wobbler magnets, and multileaf collimator and range shifter, during the irradiation, more conformal radiotherapy can be achieved. The system, which has to be adequately safe for patient irradiations, was constructed and tested from a viewpoint of safety and the quality of the dose localization realized. A secondary beam line has been constructed for use of radioactive beam in heavy-ion radiotherapy. Spot scanning method has been adapted for the beam delivery system of the radioactive beam. Dose distributions of the spot beam were measured and analyzed taking into account of aberration of the beam optics. Distributions of the stopped positron-emitter beam can be observed by PET. Pencil beam of the positron-emitter, about 1 mm size, can also be used for measurements ranges of the test beam in patients using positron camera. The positron camera, consisting of a pair of Anger-type scintillation detectors, has been developed for this verification before treatment. Wash-out effect of the positron-emitter was examined using the positron camera installed. In this report, present status of the HIMAC irradiation system is described in detail.

  6. Continuous intensity map optimization (CIMO): A novel approach to leaf sequencing in step and shoot IMRT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cao Daliang; Earl, Matthew A.; Luan, Shuang

    2006-04-15

    A new leaf-sequencing approach has been developed that is designed to reduce the number of required beam segments for step-and-shoot intensity modulated radiation therapy (IMRT). This approach to leaf sequencing is called continuous-intensity-map-optimization (CIMO). Using a simulated annealing algorithm, CIMO seeks to minimize differences between the optimized and sequenced intensity maps. Two distinguishing features of the CIMO algorithm are (1) CIMO does not require that each optimized intensity map be clustered into discrete levels and (2) CIMO is not rule-based but rather simultaneously optimizes both the aperture shapes and weights. To test the CIMO algorithm, ten IMRT patient cases weremore » selected (four head-and-neck, two pancreas, two prostate, one brain, and one pelvis). For each case, the optimized intensity maps were extracted from the Pinnacle{sup 3} treatment planning system. The CIMO algorithm was applied, and the optimized aperture shapes and weights were loaded back into Pinnacle. A final dose calculation was performed using Pinnacle's convolution/superposition based dose calculation. On average, the CIMO algorithm provided a 54% reduction in the number of beam segments as compared with Pinnacle's leaf sequencer. The plans sequenced using the CIMO algorithm also provided improved target dose uniformity and a reduced discrepancy between the optimized and sequenced intensity maps. For ten clinical intensity maps, comparisons were performed between the CIMO algorithm and the power-of-two reduction algorithm of Xia and Verhey [Med. Phys. 25(8), 1424-1434 (1998)]. When the constraints of a Varian Millennium multileaf collimator were applied, the CIMO algorithm resulted in a 26% reduction in the number of segments. For an Elekta multileaf collimator, the CIMO algorithm resulted in a 67% reduction in the number of segments. An average leaf sequencing time of less than one minute per beam was observed.« less

  7. The (n,γ) campaigns at EXILL

    NASA Astrophysics Data System (ADS)

    Jolie, J.; Régis, J.-M.; Wilmsen, D.; Ahmed, S.; Pfeiffer, M.; Saed-Samii, N.; Warr, N.; Blanc, A.; Jentschel, M.; Köster, U.; Mutti, P.; Soldner, T.; Simpson, G.; De France, G.; Urban, W.; Drouet, F.; Vancraeyenest, A.; Baczyk, P.; Czerwinski, M.; Korgul, A.; Mazzocchi, C.; Rzaca-Urban, T.; Bruce, A.; Roberts, O. J.; Fraile, L. M.; Mach, H.; Paziy, V.; Ignatov, A.; Ilieva, S.; Kröll, Th.; Scheck, M.; Thürauf, M.; Ivanova, D.; Kisyov, S.; Lalkovski, S.; Podolyák, Zs.; Regan, P. H.; Korten, W.; Zielinska, M.; Salsac, M. D.; Habs, D.; Thirolf, P. G.; Ur, C. A.; Bernards, C.; Casten, R. F.; Cooper, N.; Werner, V.; Cakirli, R. B.; Leoni, S.; Benzoni, G.; Bocchi, G.; Bottoni, S.; Crespi, F. C. L.; Fornal, B.; Cieplicka, N.; Szpak, B.; Petrache, C. M.; Leguillon, R.; John, R.; Lorenz, C.; Massarczyk, R.; Schwengner, R.; Curien, D.; Lozeva, R.; Sengele, L.; Marginean, N.; Lica, R.

    2015-05-01

    At the PF1B cold neutron beam line at the Institut Laue Langevin, the EXILL array consisting of EXOGAM, GASP and ILL-Clover detectors was used to perform (n,γ) measurements at very high coincidence rates. About ten different reactions were measured in autumn 2012 using a highly collimated cold neutron beam. In spring 2013, the EXOGAM array was combined with 16 LaBr3(Ce) scintillators in the EXILL&FATIMA campaign for the measurement of lifetimes using the generalised centroid difference method. We report on the properties of the set-ups and present first results from both campaigns.

  8. Intra-beam scattering and its application to ERL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fedotov A. V.

    Treatment of Coulomb collisions within the beam requires consideration of both large and small angle scattering. Such collisions lead to the Touschek effect and Intrabeam Scattering (IBS). The Touschek effect refers to particle loss as a result of a single collision, where only transfer from the transverse direction into longitudinal plays a role. It is important to consider this effect for ERL design to have an appropriate choice of collimation system. The IBS is a diffusion process which leads to changes of beam distribution but does not necessarily result in a beam loss. Evaluation of IBS in ERLs, where beammore » distribution is non-Gaussian, requires special treatment. Here we describe the IBS and Touschek effects with application to ERLs.« less

  9. Solar simulator for concentrator photovoltaic systems.

    PubMed

    Domínguez, César; Antón, Ignacio; Sala, Gabriel

    2008-09-15

    A solar simulator for measuring performance of large area concentrator photovoltaic (CPV) modules is presented. Its illumination system is based on a Xenon flash light and a large area collimator mirror, which simulates natural sun light. Quality requirements imposed by the CPV systems have been characterized: irradiance level and uniformity at the receiver, light collimation and spectral distribution. The simulator allows indoor fast and cost-effective performance characterization and classification of CPV systems at the production line as well as module rating carried out by laboratories.

  10. Performance improvements in temperature reconstructions of 2-D tunable diode laser absorption spectroscopy (TDLAS)

    NASA Astrophysics Data System (ADS)

    Choi, Doo-Won; Jeon, Min-Gyu; Cho, Gyeong-Rae; Kamimoto, Takahiro; Deguchi, Yoshihiro; Doh, Deog-Hee

    2016-02-01

    Performance improvement was attained in data reconstructions of 2-dimensional tunable diode laser absorption spectroscopy (TDLAS). Multiplicative Algebraic Reconstruction Technique (MART) algorithm was adopted for data reconstruction. The data obtained in an experiment for the measurement of temperature and concentration fields of gas flows were used. The measurement theory is based upon the Beer-Lambert law, and the measurement system consists of a tunable laser, collimators, detectors, and an analyzer. Methane was used as a fuel for combustion with air in the Bunsen-type burner. The data used for the reconstruction are from the optical signals of 8-laser beams passed on a cross-section of the methane flame. The performances of MART algorithm in data reconstruction were validated and compared with those obtained by Algebraic Reconstruction Technique (ART) algorithm.

  11. SU-E-T-457: Design and Characterization of An Economical 192Ir Hemi-Brain Small Animal Irradiator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grams, M; Wilson, Z; Sio, T

    Purpose: To describe the design and dosimetric characterization of a simple and economical small animal irradiator. Methods: A high dose rate 192Ir brachytherapy source from a commercially available afterloader was used with a 1.3 centimeter thick tungsten collimator to provide sharp beam penumbra suitable for hemi-brain irradiation of mice. The unit is equipped with continuous gas anesthesia to allow robust animal immobilization. Dosimetric characterization of the device was performed with Gafchromic film. The penumbra from the small animal irradiator was compared under similar collimating conditions to the penumbra from 6 MV photons, 6 MeV electrons, and 20 MeV electrons frommore » a linear accelerator as well as 300 kVp photons from an orthovoltage unit and Monte Carlo simulated 90 MeV protons. Results: The tungsten collimator provides a sharp penumbra suitable for hemi-brain irradiation, and dose rates on the order of 200 cGy/minute were achieved. The sharpness of the penumbra attainable with this device compares favorably to those measured experimentally for 6 MV photons, and 6 and 20 MeV electron beams from a linear accelerator. Additionally, the penumbra was comparable to those measured for a 300 kVp orthovoltage beam and a Monte Carlo simulated 90 MeV proton beam. Conclusions: The small animal irradiator described here can be built for under $1,000 and used in conjunction with any commercial brachytherapy afterloader to provide a convenient and cost-effective option for small animal irradiation experiments. The unit offers high dose rate delivery and sharp penumbra, which is ideal for hemi-brain irradiation of mice. With slight modifications to the design, irradiation of sites other than the brain could be accomplished easily. Due to its simplicity and low cost, the apparatus described is an attractive alternative for small animal irradiation experiments requiring a sharp penumbra.« less

  12. High-power direct diode laser output by spectral beam combining

    NASA Astrophysics Data System (ADS)

    Tan, Hao; Meng, Huicheng; Ruan, Xu; Du, Weichuan; Wang, Zhao

    2018-03-01

    We demonstrate a spectral beam combining scheme based on multiple mini-bar stacks, which have more diode laser combining elements, to increase the combined diode laser power and realize equal beam quality in both the fast and slow axes. A spectral beam combining diode laser output of 1130 W is achieved with an operating current of 75 A. When a 9.6 X de-magnifying telescope is introduced between the output mirror and the diffraction grating, to restrain cross-talk among diode laser emitters, a 710 W spectral beam combining diode laser output is achieved at the operating current of 70 A, and the beam quality on the fast and slow axes of the combined beam is about 7.5 mm mrad and 7.3 mm mrad respectively. The power reduction is caused by the existence of a couple resonator between the rear facet of the diode laser and the fast axis collimation lens, and it should be eliminated by using diode laser chips with higher front facet transmission efficiency and a fast axis collimation lens with lower residual reflectivity.

  13. Hybrid algorithm for simulating the collimated transmittance of homogeneous stratified turbid media

    PubMed Central

    Cruzado, Beatriz Morales; Atencio, José Alberto Delgado; Vázquez y Montiel, Sergio; Gómez, Erick Sarmiento

    2015-01-01

    In this work we describe the development of a program that simulates the propagation of photons through refractive and reflecting optical components such as lenses, mirrors and stops that includes a biological tissue sample as the main issue to be investigated in order to get a simulated value of light distribution, in particular, of the unscattered light. The analysis of the photons that travel through the sample is based on the program Monte Carlo Multi-Layered with some modifications that consider a Gaussian beam as initial source of light. Position, directional cosines and weight of photons exiting the turbid media are used to propagate them through an optical system. As a mean of validation of the program, we selected a typical optical system for measurement of collimated transmittance. Therefore, several tests were carried out to find the optical system that gives the theoretical collimated transmittance at different values of the optical properties of the turbid media. Along this validation, the optimal experimental configuration is found. Using this results, a comparison between the simulated optimal configuration and the experimental set-up was done, by using a colloidal suspension as a turbid media. PMID:26137375

  14. Transient beam oscillation with a highly dynamic scanner for laser beam fusion cutting

    NASA Astrophysics Data System (ADS)

    Goppold, Cindy; Pinder, Thomas; Herwig, Patrick

    2016-02-01

    Sheet metals with thicknesses >8 mm have a distinct cutting performance. The free choice of the optical configuration composed of fiber diameter, collimation, and focal length offers many opportunities to influence the static beam geometry. Previous analysis points out the limitations of this method in the thick section area. Within the present study, an experimental investigation of fiber laser fusion cutting of 12 mm stainless steel was performed by means of dynamical beam oscillation. Two standard optical setups are combined with a highly dynamic galvano-driven scanner that achieves frequencies up to 4 kHz. Dependencies of the scanner parameter, the optical circumstances, and the conventional cutting parameters are discussed. The aim is to characterize the capabilities and challenges of the dynamic beam shaping in comparison to the state-of-the-art static beam shaping. Thus, the trials are evaluated by quality criteria of the cut edge as surface roughness and burr height, the feed rate, and the cut kerf geometry. The investigation emphasizes promising procedural possibilities for improvements of the cutting performance in the case of fiber laser fusion cutting of thick stainless steel by means of the application of a highly dynamic scanner.

  15. Radiosurgery performed with the aid of a 3-mm collimator in the subthalamic nucleus and substantia nigra of the vervet monkey.

    PubMed

    De Salles, A A; Melega, W P; Laćan, G; Steele, L J; Solberg, T D

    2001-12-01

    Radiosurgery for functional neurosurgery performed using a linear accelerator (LINAC) has not been extensively characterized in preclinical studies. In the present study, the properties of a newly designed 3-mm-diameter collimator were evaluated in a dedicated LINAC, which produced lesions in the basal ganglia of vervet monkeys. Lesion formation was determined in vivo in three animals by examining magnetic resonance (MR) images to show the dose-delivery precision of targeting and the geometry and extent of the lesions. Postmortem immunohistochemical studies were conducted to determine the extent of lesion-induced radiobiological effects. In three male vervet monkeys, the subthalamic nucleus (STN; one animal) and the pars compacta of the lateral substantia nigra (SN; two animals) were targeted by a Novalis Shaped Beam Surgery System that included a 3-mm collimator and delivered a maximum dose of 150 Gy. Magnetic resonance images obtained 4, 5, and 9 months posttreatment were reviewed, and the animals were killed so that immunohistological characterizations could be made. The generation of precise radiosurgical lesions by a 3-mm collimator was validated in studies that targeted the basal ganglia of the vervet monkey. The extent of the lesions created in all animals remained restricted in diameter (< 3 mm) throughout the duration of the studies, as assessed by reviewing MR images. Histological studies showed that the lesions were contained within the STN and SN target areas and that there were persistent increases in glial fibrillary acidic protein immunoreactivity. Increases in immunoreactivity for tyrosine hydroxylase, the serotonin transporter, and the GluR1 subunit of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate glutamate receptor in penumbral regions of the lesion were suggestive of compensatory neuronal adaptations. This radiosurgical approach may be of particular interest for the induction of lesions of the STN and SN in studies of experimental parkinsonism, as well as for the development of potential radiosurgical treatments for Parkinson disease.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Y; Liu, B; Liang, B

    Purpose: Current CyberKnife treatment planning system (TPS) provided two dose calculation algorithms: Ray-tracing and Monte Carlo. Ray-tracing algorithm is fast, but less accurate, and also can’t handle irregular fields since a multi-leaf collimator system was recently introduced to CyberKnife M6 system. Monte Carlo method has well-known accuracy, but the current version still takes a long time to finish dose calculations. The purpose of this paper is to develop a GPU-based fast C/S dose engine for CyberKnife system to achieve both accuracy and efficiency. Methods: The TERMA distribution from a poly-energetic source was calculated based on beam’s eye view coordinate system,more » which is GPU friendly and has linear complexity. The dose distribution was then computed by inversely collecting the energy depositions from all TERMA points along 192 collapsed-cone directions. EGSnrc user code was used to pre-calculate energy deposition kernels (EDKs) for a series of mono-energy photons The energy spectrum was reconstructed based on measured tissue maximum ratio (TMR) curve, the TERMA averaged cumulative kernels was then calculated. Beam hardening parameters and intensity profiles were optimized based on measurement data from CyberKnife system. Results: The difference between measured and calculated TMR are less than 1% for all collimators except in the build-up regions. The calculated profiles also showed good agreements with the measured doses within 1% except in the penumbra regions. The developed C/S dose engine was also used to evaluate four clinical CyberKnife treatment plans, the results showed a better dose calculation accuracy than Ray-tracing algorithm compared with Monte Carlo method for heterogeneous cases. For the dose calculation time, it takes about several seconds for one beam depends on collimator size and dose calculation grids. Conclusion: A GPU-based C/S dose engine has been developed for CyberKnife system, which was proven to be efficient and accurate for clinical purpose, and can be easily implemented in TPS.« less

  17. SU-C-BRE-04: Microbeam-Radiation-Therapy (MRT): Characterizing a Novel MRT Device Using High Resolution 3D Dosimetry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Q; Juang, T; Bache, S

    2014-06-15

    Purpose: The feasibility of MRT has recently been demonstrated utilizing a new technology of Carbon-Nano-Tube(CNT) field emission x-ray sources.This approach can deliver very high dose(10's of Gy) in narrow stripes(sub-mm) of radiation which enables the study of novel radiation treatment approaches. Here we investigate the application of highresolution (50um isotropic) PRESAGE/Optical-CT 3D dosimetry techniques to characterize the radiation delivered in this extremely dosimetrically challenging scenario. Methods: The CNT field emission x-ray source irradiator comprises of a linear cathode array and a novel collimator alignment system. This allows a precise delivery of high-energy small beams up to 160 kVp. A cylindricalmore » dosimeter (∼2.2cm in height ∼2.5cm in diameter) was irradiated by CNT MRT delivering 3 strips of radiation with a nominal entrance dose of 32 Gy.A second dosimeter was irradiated with similar entrance dose, with a regular x-ray irradiator collimated to microscopical strip-beams. 50um (isotropic) 3D dosimetry was performed using an in-house optical-CT system designed and optimized for high resolution imaging (including a stray light deconvolution correction).The percentage depth dose (PDD), peak-to-valley ratio (PVR) and beam width (FWHM) data were obtained and analyzed in both cases. Results: High resolution 3D images were successfully achieved with the prototype system, enabling extraction of PDD and dose profiles. The PDDs for the CNT irradiation showed pronounced attenuation, but less build-up effect than that from the multibeam irradiation. The beam spacing between the three strips has an average value of 0.9mm while that for the 13 strips is 1.5 mm at a depth of 16.5 mm. The stray light corrected image shows line profiles with reduced noise and consistent PVR values. Conclusion: MRT dosimetry is extremely challenging due to the ultra small fields involved.This preliminary application of a novel, ultra-high resolution, optical-CT 3D dosimetry system shows promise, but further work is required to validate and investigate accuracy and artifacts. This work was supported by NIH R01CA100835.« less

  18. High dose-per-pulse electron beam dosimetry: Commissioning of the Oriatron eRT6 prototype linear accelerator for preclinical use.

    PubMed

    Jaccard, Maud; Durán, Maria Teresa; Petersson, Kristoffer; Germond, Jean-François; Liger, Philippe; Vozenin, Marie-Catherine; Bourhis, Jean; Bochud, François; Bailat, Claude

    2018-02-01

    The Oriatron eRT6 is an experimental high dose-per-pulse linear accelerator (linac) which was designed to deliver an electron beam with variable dose-rates, ranging from a few Gy/min up to hundreds of Gy/s. It was built to study the radiobiological effects of high dose-per-pulse/dose-rate electron beam irradiation, in the context of preclinical and cognitive studies. In this work, we report on the commissioning and beam monitoring of the Oriatron eRT6 prototype linac. The beam was characterized in different steps. The output stability was studied by performing repeated measurements over a period of 20 months. The relative output variations caused by changing beam parameters, such as the temporal electron pulse width, the pulse repetition frequency and the pulse amplitude were also analyzed. Finally, depth dose curves and field sizes were measured for two different beam settings, resulting in one beam with a conventional radiotherapy dose-rate and one with a much higher dose-rate. Measurements were performed with Gafchromic EBT3 films and with a PTW Advanced Markus ionization chamber. In addition, we developed a beam current monitoring system based on the signals from an induction torus positioned at the beam exit of the waveguide and from a graphite beam collimator. The stability of the output over repeated measurements was found to be good, with a standard deviation smaller than 1%. However, non-negligible day-to-day variations of the beam output were observed. Those output variations showed different trends depending on the dose-rate. The analysis of the relative output variation as a function of various beam parameters showed that in a given configuration, the dose-rate could be reliably varied over three orders of magnitude. Interdependence effects on the output variation between the parameters were also observed. The beam energy and field size were found to be slightly dose-rate-dependent and suitable mainly for small animal irradiation. The beam monitoring system was able to measure in a reproducible way the total charge of electrons that exit the machine, as long as the electron pulse amplitude remains above a given threshold. Furthermore, we were able to relate the charge measured with the monitoring system to the absorbed dose in a solid water phantom. The Oriatron eRT6 was successfully commissioned for preclinical use and is currently in full operation, with studies being performed on the radiobiological effects of high dose-per-pulse irradiation. © 2017 American Association of Physicists in Medicine.

  19. Sensitivity studies of beam directionality, beam size, and neutron spectrum for a fission converter-based epithermal neutron beam for boron neutron capture therapy.

    PubMed

    Sakamoto, S; Kiger, W S; Harling, O K

    1999-09-01

    Sensitivity studies of epithermal neutron beam performance in boron neutron capture therapy are presented for realistic neutron beams with varying filter/moderator and collimator/delimiter designs to examine the relative importance of neutron beam spectrum, directionality, and size. Figures of merit for in-air and in-phantom beam performance are calculated via the Monte Carlo technique for different well-optimized designs of a fission converter-based epithermal neutron beam with head phantoms as the irradiation target. It is shown that increasing J/phi, a measure of beam directionality, does not always lead to corresponding monotonic improvements in beam performance. Due to the relatively low significance, for most configurations, of its effect on in-phantom performance and the large intensity losses required to produce beams with very high J/phi, beam directionality should not be considered an important figure of merit in epithermal neutron beam design except in terms of its consequences on patient positioning and collateral dose. Hardening the epithermal beam spectrum, while maintaining the specific fast neutron dose well below the inherent hydrogen capture dose, improves beam penetration and advantage depth and, as a desirable by-product, significantly increases beam intensity. Beam figures of merit are shown to be strongly dependent on beam size relative to target size. Beam designs with J/phi approximately 0.65-0.7, specific fast neutron doses of 2-2.6x10(-13) Gy cm2/n and beam sizes equal to or larger than the size of the head target produced the deepest useful penetration, highest therapeutic ratios, and highest intensities.

  20. Correction of measured Gamma-Knife output factors for angular dependence of diode detectors and PinPoint ionization chamber.

    PubMed

    Hršak, Hrvoje; Majer, Marija; Grego, Timor; Bibić, Juraj; Heinrich, Zdravko

    2014-12-01

    Dosimetry for Gamma-Knife requires detectors with high spatial resolution and minimal angular dependence of response. Angular dependence and end effect time for p-type silicon detectors (PTW Diode P and Diode E) and PTW PinPoint ionization chamber were measured with Gamma-Knife beams. Weighted angular dependence correction factors were calculated for each detector. The Gamma-Knife output factors were corrected for angular dependence and end effect time. For Gamma-Knife beams angle range of 84°-54°. Diode P shows considerable angular dependence of 9% and 8% for the 18 mm and 14, 8, 4 mm collimator, respectively. For Diode E this dependence is about 4% for all collimators. PinPoint ionization chamber shows angular dependence of less than 3% for 18, 14 and 8 mm helmet and 10% for 4 mm collimator due to volumetric averaging effect in a small photon beam. Corrected output factors for 14 mm helmet are in very good agreement (within ±0.3%) with published data and values recommended by vendor (Elekta AB, Stockholm, Sweden). For the 8 mm collimator diodes are still in good agreement with recommended values (within ±0.6%), while PinPoint gives 3% less value. For the 4 mm helmet Diodes P and E show over-response of 2.8% and 1.8%, respectively. For PinPoint chamber output factor of 4 mm collimator is 25% lower than Elekta value which is generally not consequence of angular dependence, but of volumetric averaging effect and lack of lateral electronic equilibrium. Diodes P and E represent good choice for Gamma-Knife dosimetry. Copyright © 2014 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  1. Diode-laser-pump module with integrated signal ports for pumping amplifying fibers and method

    DOEpatents

    Savage-Leuchs,; Matthias, P [Woodinville, WA

    2009-05-26

    Apparatus and method for collimating pump light of a first wavelength from laser diode(s) into a collimated beam within an enclosure having first and second optical ports, directing pump light from the collimated beam to the first port; and directing signal light inside the enclosure between the first and second port. The signal and pump wavelengths are different. The enclosure provides a pump block having a first port that emits pump light to a gain fiber outside the enclosure and that also passes signal light either into or out of the enclosure, and another port that passes signal light either out of or into the enclosure. Some embodiments use a dichroic mirror to direct pump light to the first port and direct signal light between the first and second ports. Some embodiments include a wavelength-conversion device to change the wavelength of at least some of the signal light.

  2. A 25kW fiber-coupled diode laser for pumping applications

    NASA Astrophysics Data System (ADS)

    Malchus, Joerg; Krause, Volker; Koesters, Arnd; Matthews, David G.

    2014-03-01

    In this paper we report the development of a new fiber-coupled diode laser for pumping applications capable of generating 25 kW with four wavelengths. The delivery fiber has 2.0 mm core diameter and 0.22 NA resulting in a Beam Parameter Product (BPP) of 220 mm mrad. To achieve the specifications mentioned above a novel beam transformation technique has been developed combining two high power laser stacks in one common module. After fast axis collimation and beam reformatting a beam with a BPP of 200 mm mrad x 40 mm mrad in the slow and fast-axis is generated. Based on this architecture a customer-specific pump laser with 25 kW optical output power has been developed, in which two modules are polarization multiplexed for each wavelength (980nm, 1020nm, 1040m and 1060nm). After slow-axis collimation these wavelengths are combined using dense wavelength coupling before focusing onto the fiber endface. This new laser is based on a turn-key platform, allowing straight-forward integration into any pump application. The complete system has a footprint of less than 1.4m² and a height of less than 1.8m. The laser diodes are water cooled, achieve a wall-plug efficiency of up to 60%, and have a proven lifetime of <30,000 hours. The new beam transformation techniques open up prospects for the development of pump sources with more than 100kW of optical output power.

  3. Nanometer-scale sizing accuracy of particle suspensions on an unmodified cell phone using elastic light scattering.

    PubMed

    Smith, Zachary J; Chu, Kaiqin; Wachsmann-Hogiu, Sebastian

    2012-01-01

    We report on the construction of a Fourier plane imaging system attached to a cell phone. By illuminating particle suspensions with a collimated beam from an inexpensive diode laser, angularly resolved scattering patterns are imaged by the phone's camera. Analyzing these patterns with Mie theory results in predictions of size distributions of the particles in suspension. Despite using consumer grade electronics, we extracted size distributions of sphere suspensions with better than 20 nm accuracy in determining the mean size. We also show results from milk, yeast, and blood cells. Performing these measurements on a portable device presents opportunities for field-testing of food quality, process monitoring, and medical diagnosis.

  4. Device and method for generating a beam of acoustic energy from a borehole, and applications thereof

    DOEpatents

    Vu, Cung Khac; Sinha, Dipen N.; Pantea, Cristian; Nihei, Kurt T.; Schmitt, Denis P.; Skelt, Chirstopher

    2013-10-15

    In some aspects of the invention, a method of generating a beam of acoustic energy in a borehole is disclosed. The method includes generating a first acoustic wave at a first frequency; generating a second acoustic wave at a second frequency different than the first frequency, wherein the first acoustic wave and second acoustic wave are generated by at least one transducer carried by a tool located within the borehole; transmitting the first and the second acoustic waves into an acoustically non-linear medium, wherein the composition of the non-linear medium produces a collimated beam by a non-linear mixing of the first and second acoustic waves, wherein the collimated beam has a frequency based upon a difference between the first frequency range and the second frequency, and wherein the non-linear medium has a velocity of sound between 100 m/s and 800 m/s.

  5. Out-of-Time Beam Extinction in the MU2E Experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prebys, E. J.; Werkema, S.

    The Mu2e Experiment at Fermilab will search for the conversion of a muon to an electron in the field of an atomic nucleus with unprecedented sensitivity. The experiment requires a beam consisting of proton bunches 250 ns FW long, separated by 1.7more » $$\\mu$$ sec, with no out-of-time protons at the $$10^{10}$$ fractional level. Satisfying this "extinction" requirement is very challenging. The formation of the bunches is expected to result in an extinction on the order of $10^5$. The remaining extinction will be accomplished by a system of resonant magnets and collimators, configured such that only in-time beam is delivered to the experiment. Our simulations show that the total extinction achievable by the system is on the order of $$10^{12}$$, with an efficiency for transmitting in-time beam of 99.6%.« less

  6. Calibration techniques and results in the soft X-ray and extreme ultraviolet for components of the Extreme Ultraviolet Explorer Satellite

    NASA Technical Reports Server (NTRS)

    Malina, Roger F.; Jelinsky, Patrick; Bowyer, Stuart

    1986-01-01

    The calibration facilities and techniques for the Extreme Ultraviolet Explorer (EUVE) from 44 to 2500 A are described. Key elements include newly designed radiation sources and a collimated monochromatic EUV beam. Sample results for the calibration of the EUVE filters, detectors, gratings, collimators, and optics are summarized.

  7. Detection and laser ranging of orbital objects using optical methods

    NASA Astrophysics Data System (ADS)

    Wagner, P.; Hampf, D.; Sproll, F.; Hasenohr, T.; Humbert, L.; Rodmann, J.; Riede, W.

    2016-09-01

    Laser ranging to satellites (SLR) in earth orbit is an established technology used for geodesy, fundamental science and precise orbit determination. A combined active and passive optical measurement system using a single telescope mount is presented which performs precise ranging measurements of retro reflector equipped objects in low earth orbit (LEO). The German Aerospace Center (DLR) runs an observatory in Stuttgart where a system has been assembled completely from commercial off-the-shelf (COTS) components. The visible light directed to the tracking camera is used to perform angular measurements of objects under investigation. This is done astrometrically by comparing the apparent target position with cataloged star positions. First successful satellite laser ranging was demonstrated recently using an optical fiber directing laser pulses onto the astronomical mount. The transmitter operates at a wavelength of 1064 nm with a repetition rate of 3 kHz and pulse energy of 25 μJ. A motorized tip/tilt mount allows beam steering of the collimated beam with μrad accuracy. The returning photons reflected from the object in space are captured with the tracking telescope. A special low aberration beam splitter unit was designed to separate the infrared from visible light. This allows passive optical closed loop tracking and operation of a single photon detector for time of flight measurements at a single telescope simultaneously. The presented innovative design yields to a compact and cost effective but very precise ranging system which allows orbit determination.

  8. SU-F-T-425: Head-Scatter Off-Axis for FFF Megavoltage Photon Beams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhu, T; Penjweini, R; Dimofte, A

    Purpose: Head-scatter photons inside a clinical accelerator cause the output to change with collimator setting. On the central-axis, this contribution is well-described by output factor in air (or head-scatter factor). However, a few studies have examined this component at off-axis points. Methods: We define the head-scatter off-axis ratio, HOA, as the ratio of the water kerma in air due to head-scatter photons at the off-axis position x to the water kerma from direct primary photons on the central axis: HOA(cx,cy,xy) = (Q(cx,cy,x) – QP(cx,cy,x))/QP(cx,cy,0), where Q(cx, cy,x), QP(cx,cy,x) are charges measured by an ionization chamber in a miniphantom for collimatormore » setting cx × cy and cx × 3 cm, respectively, at off-axis point x. “Direct primary” is those photons that come from the source without interactions in the intervening structures. Results: We measured HOA for two energies (6XFFF and 6X) along X and Y jaw directions for various collimator settings. The shape of HOA has well defined penumbra for collimator setting larger than 10 × 10 cm2. Conclusion: The narrow gaussian component is interpreted as the source of photons scattered in the flattening filter and the primary collimator. The broad component is attributed to photons scattered in the secondary (variable) collimators. By a direct comparison between 6X and 6XFFF beams, we can confirm that the second component is indeed coming from collimator jaws and identify the parts coming from the primary collimator and the flattening filter, respectively.« less

  9. Operational performance of a low cost, air mass 2 solar simulator

    NASA Technical Reports Server (NTRS)

    Yass, K.; Curtis, H. B.

    1975-01-01

    Modifications and improvements on a low cost air mass 2 solar simulator are discussed. The performance characteristics of total irradiance, uniformity of irradiance, spectral distribution, and beam subtense angle are presented. The simulator consists of an array of tungsten halogen lamps hexagonally spaced in a plane. A corresponding array of plastic Fresnel lenses shapes the output beam such that the simulator irradiates a 1.2 m by 1.2 m area with uniform collimated irradiance. Details are given concerning individual lamp output measurements and placement of the lamps. Originally, only the direct component of solar irradiance was simulated. Since the diffuse component may affect the performance of some collectors, the capability to simulate it is being added. An approach to this diffuse addition is discussed.

  10. Multi-aperture laser transmissometer system for long-path aerosol extinction rate measurement.

    PubMed

    Wu, Chensheng; Rzasa, John R; Ko, Jonathan; Paulson, Daniel A; Coffaro, Joseph; Spychalsky, Jonathan; Crabbs, Robert F; Davis, Christopher C

    2018-01-20

    We present the theory, design, simulation, and experimental evaluations of a new laser transmissometer system for aerosol extinction rate measurement over long paths. The transmitter emits an ON/OFF modulated Gaussian beam that does not require strict collimation. The receiver uses multiple point detectors to sample the sub-aperture irradiance of the arriving beam. The sparse detector arrangement makes our transmissometer system immune to turbulence-induced beam distortion and beam wander caused by the atmospheric channel. Turbulence effects often cause spatial discrepancies in beam propagation and lead to miscalculation of true power loss when using the conventional approach of measuring the total beam power directly with a large-aperture optical concentrator. Our transmissometer system, on the other hand, combines the readouts from distributed detectors to rule out turbulence-induced temporal power fluctuations. As a result, we show through both simulation and field experiments that our transmissometer system works accurately with turbulence strength Cn2 up to 10 -12   m -2/3 over a typical 1-km atmospheric channel. In application, our turbulence- and weather-resistant laser transmissometer system has significant advantages for the measurement and study of aerosol concentration, absorption, and scattering properties, which are crucial for directed energy systems, ground-level free-space optical communication systems, environmental monitoring, and weather forecasting.

  11. Software tool for portal dosimetry research.

    PubMed

    Vial, P; Hunt, P; Greer, P B; Oliver, L; Baldock, C

    2008-09-01

    This paper describes a software tool developed for research into the use of an electronic portal imaging device (EPID) to verify dose for intensity modulated radiation therapy (IMRT) beams. A portal dose image prediction (PDIP) model that predicts the EPID response to IMRT beams has been implemented into a commercially available treatment planning system (TPS). The software tool described in this work was developed to modify the TPS PDIP model by incorporating correction factors into the predicted EPID image to account for the difference in EPID response to open beam radiation and multileaf collimator (MLC) transmitted radiation. The processes performed by the software tool include; i) read the MLC file and the PDIP from the TPS, ii) calculate the fraction of beam-on time that each point in the IMRT beam is shielded by MLC leaves, iii) interpolate correction factors from look-up tables, iv) create a corrected PDIP image from the product of the original PDIP and the correction factors and write the corrected image to file, v) display, analyse, and export various image datasets. The software tool was developed using the Microsoft Visual Studio.NET framework with the C# compiler. The operation of the software tool was validated. This software provided useful tools for EPID dosimetry research, and it is being utilised and further developed in ongoing EPID dosimetry and IMRT dosimetry projects.

  12. Method and apparatus for automatically tracking a workpiece surface. [Patents

    DOEpatents

    Not Available

    1981-02-03

    Laser cutting concepts and apparatus have been developed for cutting the shroud of the core fuel subassemblies. However, much care must be taken in the accuracy of the cutting since the fuel rods within the shroud often become warped and are forced into direct contact with the shroud in random regions. Thus, in order to cut the nuclear fuel rod shroud accurately so as not to puncture the cladding of the fuel rods, and to insure optimal cutting efficiency and performance, the focal point of beam need be maintained accurately at the workpiece surface. It becomes necessary to detect deviations in the level of the workpiece surface accurately in connection with the cutting process. Therefore, a method and apparatus for tracking the surface of a workpiece being cut by a laser beam coming from a focus head assembly is disclosed which includes two collimated laser beams directed onto the work-piece surface at spaced points by beam directing optics in generally parallel planes of incidence. A shift in spacing between the two points is detected by means of a video camera system and processed by a computer to yield a workpiece surface displacement signal which is input to a motor which raises or lowers the beam focus head accordingly.

  13. Modular high power diode lasers with flexible 3D multiplexing arrangement optimized for automated manufacturing

    NASA Astrophysics Data System (ADS)

    Könning, Tobias; Bayer, Andreas; Plappert, Nora; Faßbender, Wilhelm; Dürsch, Sascha; Küster, Matthias; Hubrich, Ralf; Wolf, Paul; Köhler, Bernd; Biesenbach, Jens

    2018-02-01

    A novel 3-dimensional arrangement of mirrors is used to re-arrange beams from 1-D and 2-D high power diode laser arrays. The approach allows for a variety of stacking geometries, depending on individual requirements. While basic building blocks, including collimating optics, always remain the same, most adaptations can be realized by simple rearrangement of a few optical components. Due to fully automated alignment processes, the required changes can be realized in software by changing coordinates, rather than requiring customized mechanical components. This approach minimizes development costs due to its flexibility, while reducing overall product cost by using similar building blocks for a variety of products and utilizing a high grade of automation. The modules can be operated with industrial grade water, lowering overall system and maintenance cost. Stackable macro coolers are used as the smallest building block of the system. Each cooler can hold up to five diode laser bars. Micro optical components, collimating the beam, are mounted directly to the cooler. All optical assembly steps are fully automated. Initially, the beams from all laser bars propagate in the same direction. Key to the concept is an arrangement of deflectors, which re-arrange the beams into a 2-D array of the desired shape and high fill factor. Standard multiplexing techniques like polarization- or wavelengths-multiplexing have been implemented as well. A variety of fiber coupled modules ranging from a few hundred watts of optical output power to multiple kilowatts of power, as well as customized laser spot geometries like uniform line sources, have been realized.

  14. Sci-Thur PM – Colourful Interactions: Highlights 01: Design to delivery of spatially fractionated mini-beam canine radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alexander, Andrew; Crewson, Cody; Davis, William

    Spatial fractionation of radiation using arrays of narrow parallel micro-planar beams (less than 1 mm), is a relatively new concept with many unknowns specifically within the underlying biology of cell death. A tungsten collimator has been designed to produce mini-beams with a Varian linear accelerator for translational animal research into the effectiveness of spatial fractionation mini-beam radiotherapy (MBRT). This work presents the treatment planning process and workflow for the application of MBRT treatments within a clinical study. For patient dose calculations, the MBRT collimator was incorporated into a Monte Carlo based treatment planning system called MMCTP. Treatment planning was splitmore » between Eclipse and MMCTP, as the field apertures were determined within Eclipse prior to being sent to MMCTP for dose calculations. The calculated plan was transferred back into Aria with updated MUs per field for patient treatment. Patients were positioned within a vac-lock bag lying prone with a bite block and a thermoplastic mask to immobilize the head. Prior to treatment, a delivery verification plan was created within MMCTP. DQA output measurements of the treatment fields agreed with the calculated dose to within 1.5%. We have presented a workflow for MBRT treatments that include the planning technique, dose calculation method, DQA process and data integration into a record and verify system. The clinical study following this workflow represent the first series of linac based MBRT patients and depending on the clinical outcome of the study, our technique could be applied to human MBRT treatments.« less

  15. Wavefront reversal technique for self-referencing collimation testing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hii, King Ung; Kwek, Kuan Hiang

    2010-02-01

    We present a wavefront reversal technique to produce a dual-field fringe pattern for self-referencing collimation testing in wedge-plate lateral-shear interferometry. The method requires only a suitably placed cubic beam splitter to produce two replicas of the fringe field formed by the wedge-plate lateral-shear interferometer. One of the replicas has a fringe pattern that is the reverse of the other. With these two fringe fields, the collimation testing has a built-in reference, and the detection sensitivity is twice that of a single-wedge-plate technique.

  16. Dose calculation of dynamic trajectory radiotherapy using Monte Carlo.

    PubMed

    Manser, P; Frauchiger, D; Frei, D; Volken, W; Terribilini, D; Fix, M K

    2018-04-06

    Using volumetric modulated arc therapy (VMAT) delivery technique gantry position, multi-leaf collimator (MLC) as well as dose rate change dynamically during the application. However, additional components can be dynamically altered throughout the dose delivery such as the collimator or the couch. Thus, the degrees of freedom increase allowing almost arbitrary dynamic trajectories for the beam. While the dose delivery of such dynamic trajectories for linear accelerators is technically possible, there is currently no dose calculation and validation tool available. Thus, the aim of this work is to develop a dose calculation and verification tool for dynamic trajectories using Monte Carlo (MC) methods. The dose calculation for dynamic trajectories is implemented in the previously developed Swiss Monte Carlo Plan (SMCP). SMCP interfaces the treatment planning system Eclipse with a MC dose calculation algorithm and is already able to handle dynamic MLC and gantry rotations. Hence, the additional dynamic components, namely the collimator and the couch, are described similarly to the dynamic MLC by defining data pairs of positions of the dynamic component and the corresponding MU-fractions. For validation purposes, measurements are performed with the Delta4 phantom and film measurements using the developer mode on a TrueBeam linear accelerator. These measured dose distributions are then compared with the corresponding calculations using SMCP. First, simple academic cases applying one-dimensional movements are investigated and second, more complex dynamic trajectories with several simultaneously moving components are compared considering academic cases as well as a clinically motivated prostate case. The dose calculation for dynamic trajectories is successfully implemented into SMCP. The comparisons between the measured and calculated dose distributions for the simple as well as for the more complex situations show an agreement which is generally within 3% of the maximum dose or 3mm. The required computation time for the dose calculation remains the same when the additional dynamic moving components are included. The results obtained for the dose comparisons for simple and complex situations suggest that the extended SMCP is an accurate dose calculation and efficient verification tool for dynamic trajectory radiotherapy. This work was supported by Varian Medical Systems. Copyright © 2018. Published by Elsevier GmbH.

  17. Development and deployment of the Collimated Directional Radiation Detection System

    NASA Astrophysics Data System (ADS)

    Guckes, Amber L.; Barzilov, Alexander

    2017-09-01

    The Collimated Directional Radiation Detection System (CDRDS) is capable of imaging radioactive sources in two dimensions (as a directional detector). The detection medium of the CDRDS is a single Cs2LiYCl6:Ce3+ scintillator cell enriched in 7Li (CLYC-7). The CLYC-7 is surrounded by a heterogeneous high-density polyethylene (HDPE) and lead (Pb) collimator. These materials make-up a coded aperture inlaid in the collimator. The collimator is rotated 360° by a stepper motor which enables time-encoded imaging of a radioactive source. The CDRDS is capable of spectroscopy and pulse shape discrimination (PSD) of photons and fast neutrons. The measurements of a radioactive source are carried out in discrete time steps that correlate to the angular rotation of the collimator. The measurement results are processed using a maximum likelihood expectation (MLEM) algorithm to create an image of the measured radiation. This collimator design allows for the directional detection of photons and fast neutrons simultaneously by utilizing only one CLYC-7 scintillator. Directional detection of thermal neutrons can also be performed by utilizing another suitable scintillator. Moreover, the CDRDS is portable, robust, and user friendly. This unit is capable of utilizing wireless data transfer for possible radiation mapping and network-centric applications. The CDRDS was tested by performing laboratory measurements with various gamma-ray and neutron sources.

  18. SU-F-T-366: Dosimetric Parameters Enhancement of 120-Leaf Millennium MLC Using EGSnrc and IAEA Phase-Space Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haddad, K; Alopoor, H

    Purpose: Recently, the multileaf collimators (MLC) have become an important part of any LINAC collimation systems because they reduce the treatment planning time and improves the conformity. Important factors that affects the MLCs collimation performance are leaves material composition and their thickness. In this study, we investigate the main dosimetric parameters of 120-leaf Millennium MLC including dose in the buildup point, physical penumbra as well as average and end leaf leakages. Effects of the leaves geometry and density on these parameters are evaluated Methods: From EGSnrc Monte Carlo code, BEAMnrc and DOSXYZnrc modules are used to evaluate the dosimetric parametersmore » of a water phantom exposed to a Varian xi for 100cm SSD. Using IAEA phasespace data just above MLC (Z=46cm) and BEAMnrc, for the modified 120-leaf Millennium MLC a new phase space data at Z=52cm is produces. The MLC is modified both in leaf thickness and material composition. EGSgui code generates 521ICRU library for tungsten alloys. DOSXYZnrc with the new phase space evaluates the dose distribution in a water phantom of 60×60×20 cm3 with voxel size of 4×4×2 mm3. Using DOSXYZnrc dose distributions for open beam and closed beam as well as the leakages definition, end leakage, average leakage and physical penumbra are evaluated. Results: A new MLC with improved dosimetric parameters is proposed. The physical penumbra for proposed MLC is 4.7mm compared to 5.16 mm for Millennium. Average leakage in our design is reduced to 1.16% compared to 1.73% for Millennium, the end leaf leakage suggested design is also reduced to 4.86% compared to 7.26% of Millennium. Conclusion: The results show that the proposed MLC with enhanced dosimetric parameters could improve the conformity of treatment planning.« less

  19. Biological and dosimetric characterisation of spatially fractionated proton minibeams

    NASA Astrophysics Data System (ADS)

    Meyer, Juergen; Stewart, Robert D.; Smith, Daniel; Eagle, James; Lee, Eunsin; Cao, Ning; Ford, Eric; Hashemian, Reza; Schuemann, Jan; Saini, Jatinder; Marsh, Steve; Emery, Robert; Dorman, Eric; Schwartz, Jeff; Sandison, George

    2017-12-01

    The biological effectiveness of proton beams varies with depth, spot size and lateral distance from the beam central axis. The aim of this work is to incorporate proton relative biological effectiveness (RBE) and equivalent uniform dose (EUD) considerations into comparisons of broad beam and highly modulated proton minibeams. A Monte Carlo model of a small animal proton beamline is presented. Dose and variable RBE is calculated on a per-voxel basis for a range of energies (30-109 MeV). For an open beam, the RBE values at the beam entrance ranged from 1.02-1.04, at the Bragg peak (BP) from 1.3 to 1.6, and at the distal end of the BP from 1.4 to 2.0. For a 50 MeV proton beam, a minibeam collimator designed to produce uniform dose at the depth of the BP peak, had minimal impact on the open beam RBE values at depth. RBE changes were observed near the surface when the collimator was placed flush with the irradiated object, due to a higher neutron contribution derived from proton interactions with the collimator. For proton minibeams, the relative mean RBE weighted entrance dose (RWD) was ~25% lower than the physical mean dose. A strong dependency of the EUD with fraction size was observed. For 20 Gy fractions, the EUD varied widely depending on the radiosensitivity of the cells. For radiosensitive cells, the difference was up to ~50% in mean dose and ~40% in mean RWD and the EUD trended towards the valley dose rather than the mean dose. For comparative studies of uniform dose with spatially fractionated proton minibeams, EUD derived from a per-voxel RWD distribution is recommended for biological assessments of reproductive cell survival and related endpoints.

  20. Biological and dosimetric characterisation of spatially fractionated proton minibeams.

    PubMed

    Meyer, Juergen; Stewart, Robert D; Smith, Daniel; Eagle, James; Lee, Eunsin; Cao, Ning; Ford, Eric; Hashemian, Reza; Schuemann, Jan; Saini, Jatinder; Marsh, Steve; Emery, Robert; Dorman, Eric; Schwartz, Jeff; Sandison, George

    2017-11-21

    The biological effectiveness of proton beams varies with depth, spot size and lateral distance from the beam central axis. The aim of this work is to incorporate proton relative biological effectiveness (RBE) and equivalent uniform dose (EUD) considerations into comparisons of broad beam and highly modulated proton minibeams. A Monte Carlo model of a small animal proton beamline is presented. Dose and variable RBE is calculated on a per-voxel basis for a range of energies (30-109 MeV). For an open beam, the RBE values at the beam entrance ranged from 1.02-1.04, at the Bragg peak (BP) from 1.3 to 1.6, and at the distal end of the BP from 1.4 to 2.0. For a 50 MeV proton beam, a minibeam collimator designed to produce uniform dose at the depth of the BP peak, had minimal impact on the open beam RBE values at depth. RBE changes were observed near the surface when the collimator was placed flush with the irradiated object, due to a higher neutron contribution derived from proton interactions with the collimator. For proton minibeams, the relative mean RBE weighted entrance dose (RWD) was ~25% lower than the physical mean dose. A strong dependency of the EUD with fraction size was observed. For 20 Gy fractions, the EUD varied widely depending on the radiosensitivity of the cells. For radiosensitive cells, the difference was up to ~50% in mean dose and ~40% in mean RWD and the EUD trended towards the valley dose rather than the mean dose. For comparative studies of uniform dose with spatially fractionated proton minibeams, EUD derived from a per-voxel RWD distribution is recommended for biological assessments of reproductive cell survival and related endpoints.

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