16S metagenomic analysis reveals adaptability of a mixed-PAH-degrading consortium isolated from crude oil-contaminated seawater to changing environmental conditions.

PubMed

Muangchinda, Chanokporn; Rungsihiranrut, Adisan; Prombutara, Pinidphon; Soonglerdsongpha, Suwat; Pinyakong, Onruthai

2018-05-29

A bacterial consortium, named SWO, was enriched from crude oil-contaminated seawater from Phrao Bay in Rayong Province, Thailand, after a large oil spill in 2013. The bacterial consortium degraded a polycyclic aromatic hydrocarbon (PAH) mixture consisting of phenanthrene, anthracene, fluoranthene, and pyrene (50 mg L -1 each) by approximately 73%, 69%, 52%, and 48%, respectively, within 21 days. This consortium exhibited excellent adaptation to a wide range of environmental conditions. It could degrade a mixture of four PAHs under a range of pH values (4.0-9.0), temperatures (25 °C-37 °C), and salinities (0-10 g L -1 with NaCl). In addition, this consortium degraded 20-30% of benzo[a]pyrene and perylene (10 mg L -1 each), high molecular weight PAHs, in the presence of other PAHs within 35 days, and degraded 40% of 2% (v/v) crude oil within 20 days. The 16S rRNA gene amplicon sequencing analysis demonstrated that Pseudomonas and Methylophaga were the dominant genera of consortium SWO in almost all treatments, while Pseudidiomarina, Thalassospira and Alcanivorax were predominant under higher salt concentrations. Moreover, Pseudomonas and Alcanivorax were dominant in the crude oil-degradation treatment. Our results suggest that the consortium SWO maintained its biodegradation ability by altering the bacterial community profile upon encountering changes in the environmental conditions. Copyright © 2018 Elsevier B.V. All rights reserved.

Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium.

PubMed

Sarwer, David B; Dilks, Rebecca J; Spitzer, Jacqueline C; Berkowitz, Robert I; Wadden, Thomas A; Moore, Renee H; Chittams, Jesse L; Brandt, Mary L; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Xanthakos, Stavra A; Zeller, Meg H; Jenkins, Todd M; Inge, Thomas H

2017-12-01

A growing number of studies suggest that bariatric surgery is safe and effective for adolescents with severe obesity. However, surprisingly little is known about changes in dietary intake and eating behavior of adolescents who undergo bariatric surgery. Investigate changes in dietary intake and eating behavior of adolescents with obesity who underwent bariatric surgery (n = 119) or lifestyle modification (LM) (n = 169). University-based health systems METHODS: A prospective investigation of 288 participants (219 female and 69 male) prior to bariatric surgery or LM and again 6, 12, and 24 months (surgery patients only) after treatment. Measures included changes in weight, macronutrient intake, eating behavior, and relevant demographic and physiological variables. Adolescents who underwent bariatric surgery experienced significantly greater weight loss than those who received LM. The two groups differed in self-reported intake of a number of macronutrients at 6 and 12 months from baseline, but not total caloric intake. Patients treated with surgery, compared to those treated with LM, also reported significantly greater reductions in a number of disordered eating symptoms. After bariatric surgery, greater weight loss from postoperative month 6 to 12 was associated with self-reported weight consciousness, craving for sweets, and consumption of zinc. Adolescents who underwent bariatric surgery, compared to those who received LM, reported significantly greater reductions in weight after 1 year. They also reported greater reductions in disordered eating symptoms. These findings provide new information on changes in dietary intake and eating behavior among adolescents who undergo bariatric surgery.

Battery Test Manual For 12 Volt Start/Stop Hybrid Electric Vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belt, Jeffrey R.

This manual was prepared by and for the United Stated Advanced Battery Consortium (USABC) Electrochemical Energy Storage Team. It is based on the targets established for 12 Volt Start/Stop energy storage development and is similar (with some important changes) to an earlier manual for the former FreedomCAR program. The specific procedures were developed primarily to characterize the performance of energy storage devices relative to the USABC requirements. However, it is anticipated that these procedures will have some utility for characterizing 12 Volt Start/Stop hybrid energy storage device behavior in general.

External RNA Controls Consortium Beta Version Update.

PubMed

Lee, Hangnoh; Pine, P Scott; McDaniel, Jennifer; Salit, Marc; Oliver, Brian

2016-01-01

Spike-in RNAs are valuable controls for a variety of gene expression measurements. The External RNA Controls Consortium developed test sets that were used in a number of published reports. Here we provide an authoritative table that summarizes, updates, and corrects errors in the test version that ultimately resulted in the certified Standard Reference Material 2374. We have noted existence of anti-sense RNA controls in the material, corrected sub-pool memberships, and commented on control RNAs that displayed inconsistent behavior.

Prebiotics Mediate Microbial Interactions in a Consortium of the Infant Gut Microbiome.

PubMed

Medina, Daniel A; Pinto, Francisco; Ovalle, Aline; Thomson, Pamela; Garrido, Daniel

2017-10-04

Composition of the gut microbiome is influenced by diet. Milk or formula oligosaccharides act as prebiotics, bioactives that promote the growth of beneficial gut microbes. The influence of prebiotics on microbial interactions is not well understood. Here we investigated the transformation of prebiotics by a consortium of four representative species of the infant gut microbiome, and how their interactions changed with dietary substrates. First, we optimized a culture medium resembling certain infant gut parameters. A consortium containing Bifidobacterium longum subsp. infantis , Bacteroides vulgatus , Escherichia coli and Lactobacillus acidophilus was grown on fructooligosaccharides (FOS) or 2'-fucosyllactose (2FL) in mono- or co-culture. While Bi. infantis and Ba. vulgatus dominated growth on 2FL, their combined growth was reduced. Besides, interaction coefficients indicated strong competition, especially on FOS. While FOS was rapidly consumed by the consortium, B. infantis was the only microbe displaying significant consumption of 2FL. Acid production by the consortium resembled the metabolism of microorganisms dominating growth in each substrate. Finally, the consortium was tested in a bioreactor, observing similar predominance but more pronounced acid production and substrate consumption. This study indicates that the chemical nature of prebiotics modulate microbial interactions in a consortium of infant gut species.

From Start-up to Sustainability: A Decade of Collaboration to Shape the Future of Nursing.

PubMed

Gubrud, Paula; Spencer, Angela G; Wagner, Linda

This article describes progress the Oregon Consortium for Nursing Education has made toward addressing the academic progression goals provided by the 2011 Institute of Medicine's Future of Nursing: Leading Change, Advancing Health report. The history of the consortium's development is described, emphasizing the creation of an efficient and sustainable organization infrastructure that supports a shared curriculum provided through a community college/university partnership. Data and analysis describing progress and challenges related to supporting a shared curriculum and increasing access and affordability for nursing education across the state are presented. We identified four crucial attributes of maintaining collaborative community that have been cultivated to assure the consortium continues to make progress toward reaching the Institute of Medicine's Future of Nursing goals. Oregon Consortium for Nursing Education provides important lessons learned for other statewide consortiums to consider when developing plans for sustainability.

Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part I—Psychiatric and Behavioral Interventions

PubMed Central

Murphy, Tanya; Leckman, James; Shaw, Richard; Williams, Kyle; Kapphahn, Cynthia; Frankovich, Jennifer; Geller, Daniel; Bernstein, Gail; Chang, Kiki; Elia, Josephine; Swedo, Susan

2017-01-01

Abstract Objective: This article outlines the consensus guidelines for symptomatic treatment for children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Syndrome Associated with Streptococcal Infection (PANDAS). Methods: Extant literature on behavioral, psychotherapeutic, and psychopharmacologic treatments for PANS and PANDAS was reviewed. Members of the PANS Research Consortium pooled their clinical experiences to find agreement on treatment of PANS and PANDAS symptoms. Results: Current guidelines result from consensus among the Consortium members. Conclusion: While underlying infectious and inflammatory processes in PANS and PANDAS patients are treated, psychiatric and behavioral symptoms need simultaneous treatment to decrease suffering and improve adherence to therapeutic intervention. Psychological, behavioral, and psychopharmacologic interventions tailored to each child's presentation can provide symptom improvement and improve functioning during both the acute and chronic stages of illness. In general, typical evidence-based interventions are appropriate for the varied symptoms of PANS and PANDAS. Individual differences in expected response to psychotropic medication may require marked reduction of initial treatment dose. Antimicrobials and immunomodulatory therapies may be indicated, as discussed in Parts 2 and 3 of this guideline series. PMID:28722481

Social and behavioral research in genomic sequencing: approaches from the Clinical Sequencing Exploratory Research Consortium Outcomes and Measures Working Group.

PubMed

Gray, Stacy W; Martins, Yolanda; Feuerman, Lindsay Z; Bernhardt, Barbara A; Biesecker, Barbara B; Christensen, Kurt D; Joffe, Steven; Rini, Christine; Veenstra, David; McGuire, Amy L

2014-10-01

The routine use of genomic sequencing in clinical medicine has the potential to dramatically alter patient care and medical outcomes. To fully understand the psychosocial and behavioral impact of sequencing integration into clinical practice, it is imperative that we identify the factors that influence sequencing-related decision making and patient outcomes. In an effort to develop a collaborative and conceptually grounded approach to studying sequencing adoption, members of the National Human Genome Research Institute's Clinical Sequencing Exploratory Research Consortium formed the Outcomes and Measures Working Group. Here we highlight the priority areas of investigation and psychosocial and behavioral outcomes identified by the Working Group. We also review some of the anticipated challenges to measurement in social and behavioral research related to genomic sequencing; opportunities for instrument development; and the importance of qualitative, quantitative, and mixed-method approaches. This work represents the early, shared efforts of multiple research teams as we strive to understand individuals' experiences with genomic sequencing. The resulting body of knowledge will guide recommendations for the optimal use of sequencing in clinical practice.

Treatment Fidelity Among Family Health Promoters Delivering a Physical Activity and Nutrition Intervention to Immigrant and Refugee Families.

PubMed

Bronars, Carrie A; Hanza, Marcelo M; Meiers, Sonja J; Patten, Christi A; Clark, Matthew M; Nigon, Julie A; Weis, Jennifer A; Wieland, Mark L; Sia, Irene G

2017-04-01

Lack of treatment fidelity can be an important source of variation affecting the credibility and utility of outcomes from behavioral intervention research. Development and implementation of a well-designed treatment fidelity plan, especially with research involving underserved populations, requires careful conceptualization of study needs in conjunction with what is feasible in the population. The purpose of this article is to review a fidelity-monitoring plan consistent with the National Institutes of Health Behavior Change Consortium guidelines (e.g., design, training, delivery, receipt, and enactment) for an intervention trial designed to improve physical activity and nutrition among immigrant and refugee families. Description of the fidelity monitoring plan is provided and challenges related to monitoring treatment fidelity in a community-based participatory intervention for immigrant and refugee families are discussed.

Gender Differences in HIV Risk Behaviors Among Persons Involved in the U.S. Criminal Justice System and Living with HIV or at Risk for HIV: A "Seek, Test, Treat, and Retain" Harmonization Consortium.

PubMed

Loeliger, Kelsey B; Biggs, Mary L; Young, Rebekah; Seal, David W; Beckwith, Curt G; Kuo, Irene; Gordon, Michael S; Altice, Frederick L; Ouellet, Lawrence J; Cunningham, William E; Young, Jeremy D; Springer, Sandra A

2017-10-01

The U.S. female criminal justice (CJ) population is rapidly growing, yet large-scale studies exploring gender-specific HIV risk behaviors in the CJ population are lacking. This analysis uses baseline data on adults with a CJ history from eight U.S. studies in an NIH-funded "Seek, Test, Treat, Retain" harmonization consortium. Data were collected using a standardized HIV risk behavior assessment tool and pooled across studies to describe participants' characteristics and risk behaviors. Multilevel mixed-effects logistic regression models were used to test for gender-based behavior differences. Among 784 HIV-positive (21.4% female) and 5521 HIV-negative (8.5% female) participants, HIV-positive women had higher odds than HIV-positive men of engaging in condomless sexual intercourse (AOR 1.84 [1.16-2.95]) with potentially sero-discordant partners (AOR 2.40 [1.41-4.09]) and of sharing injection equipment (AOR 3.36 [1.31-8.63]). HIV risk reduction interventions targeting CJ-involved women with HIV are urgently needed as this population may represent an under-recognized potential source of HIV transmission.

Using Research Evidence to Reframe the Policy Debate Around Mental Illness and Guns: Process and Recommendations

PubMed Central

Frattaroli, Shannon; Appelbaum, Paul S.; Bonnie, Richard J.; Grilley, Anna; Horwitz, Joshua; Swanson, Jeffrey W.; Webster, Daniel W.

2014-01-01

Recent mass shootings have prompted a national dialogue around mental illness and gun policy. To advance an evidence-informed policy agenda on this controversial issue, we formed a consortium of national gun violence prevention and mental health experts. The consortium agreed on a guiding principle for future policy recommendations: restricting firearm access on the basis of certain dangerous behaviors is supported by the evidence; restricting access on the basis of mental illness diagnoses is not. We describe the group’s process and recommendations. PMID:25211757

Using research evidence to reframe the policy debate around mental illness and guns: process and recommendations.

PubMed

McGinty, Emma E; Frattaroli, Shannon; Appelbaum, Paul S; Bonnie, Richard J; Grilley, Anna; Horwitz, Joshua; Swanson, Jeffrey W; Webster, Daniel W

2014-11-01

Recent mass shootings have prompted a national dialogue around mental illness and gun policy. To advance an evidence-informed policy agenda on this controversial issue, we formed a consortium of national gun violence prevention and mental health experts. The consortium agreed on a guiding principle for future policy recommendations: restricting firearm access on the basis of certain dangerous behaviors is supported by the evidence; restricting access on the basis of mental illness diagnoses is not. We describe the group's process and recommendations.

NASA Systems Engineering Research Consortium: Defining the Path to Elegance in Systems

NASA Technical Reports Server (NTRS)

Watson, Michael D.; Farrington, Phillip A.

2016-01-01

The NASA Systems Engineering Research Consortium was formed at the end of 2010 to study the approaches to producing elegant systems on a consistent basis. This has been a transformative study looking at the engineering and organizational basis of systems engineering. The consortium has engaged in a variety of research topics to determine the path to elegant systems. In the second year of the consortium, a systems engineering framework emerged which structured the approach to systems engineering and guided our research. This led in the third year to set of systems engineering postulates that the consortium is continuing to refine. The consortium has conducted several research projects that have contributed significantly to the understanding of systems engineering. The consortium has surveyed the application of the NASA 17 systems engineering processes, explored the physics and statistics of systems integration, and considered organizational aspects of systems engineering discipline integration. The systems integration methods have included system exergy analysis, Akaike Information Criteria (AIC), State Variable Analysis, Multidisciplinary Coupling Analysis (MCA), Multidisciplinary Design Optimization (MDO), System Cost Modelling, System Robustness, and Value Modelling. Organizational studies have included the variability of processes in change evaluations, margin management within the organization, information theory of board structures, social categorization of unintended consequences, and initial looks at applying cognitive science to systems engineering. Consortium members have also studied the bidirectional influence of policy and law with systems engineering.

NASA Systems Engineering Research Consortium: Defining the Path to Elegance in Systems

NASA Technical Reports Server (NTRS)

Watson, Michael D.; Farrington, Phillip A.

2016-01-01

The NASA Systems Engineering Research Consortium was formed at the end of 2010 to study the approaches to producing elegant systems on a consistent basis. This has been a transformative study looking at the engineering and organizational basis of systems engineering. The consortium has engaged in a variety of research topics to determine the path to elegant systems. In the second year of the consortium, a systems engineering framework emerged which structured the approach to systems engineering and guided our research. This led in the third year to set of systems engineering postulates that the consortium is continuing to refine. The consortium has conducted several research projects that have contributed significantly to the understanding of systems engineering. The consortium has surveyed the application of the NASA 17 systems engineering processes, explored the physics and statistics of systems integration, and considered organizational aspects of systems engineering discipline integration. The systems integration methods have included system energy analysis, Akaike Information Criteria (AIC), State Variable Analysis, Multidisciplinary Coupling Analysis (MCA), Multidisciplinary Design Optimization (MDO), System Cost Modeling, System Robustness, and Value Modeling. Organizational studies have included the variability of processes in change evaluations, margin management within the organization, information theory of board structures, social categorization of unintended consequences, and initial looks at applying cognitive science to systems engineering. Consortium members have also studied the bidirectional influence of policy and law with systems engineering.

NREL to Helm Laboratory Consortium on Vehicle Connectivity and Automation |

Science.gov Websites

automation, integrated multi-modal transportation systems, behavioral and decision science, urban science money, reduce emissions, save lives, and reshape the urban environment," says Gearhart. Other NREL

Teaching Behavior and Sport History. AAHPER Research Consortium Symposium Papers. Volume 1, Book 1.

ERIC Educational Resources Information Center

Corbin, Charles B., Ed.

This collection of symposium papers is published for members of the American Alliance for Health, Physical Education, and Recreation with the intention of providing current synthesis of research in physical education. This volume contains papers discussing and analyzing research on teacher behaviors in the field of athletics and movement education…

Successive changes in community structure of an ethylbenzene-degrading sulfate-reducing consortium.

PubMed

Nakagawa, Tatsunori; Sato, Shinya; Yamamoto, Yoko; Fukui, Manabu

2002-06-01

The microbial community structure and successive changes in a mesophilic ethylbenzene-degrading sulfate-reducing consortium were for the first time clarified by the denaturing gradient gel electrophoresis (DGGE) analysis of the PCR amplified 16S rRNA gene fragments. At least ten bands on the DGGE gel were detected in the stationary phase. Phylogenetic analysis of the DGGE bands revealed that the consortium consisted of different eubacterial phyla including the delta subgroup of Proteobacteria, the order Sphingobacteriales, the order Spirochaetales, and the unknown bacterium. The most abundant band C was closely related to strain mXyS1, an m-xylene-degrading sulfate-reducing bacterium (SRB), and occurred as a sole band on DGGE gels in the logarithmic growth phase that 40% ethylbenzene was consumed accompanied by sulfide production. During further prolonged incubation, the dominancy of band C did not change. These results suggest that SRB corresponds to the most abundant band C and contributes mainly to the degradation of ethylbenzene coupled with sulfate reduction.

Stable carbon isotope fractionation of chlorinated ethenes by a microbial consortium containing multiple dechlorinating genes.

PubMed

Liu, Na; Ding, Longzhen; Li, Haijun; Zhang, Pengpeng; Zheng, Jixing; Weng, Chih-Huang

2018-08-01

The study aimed to determine the possible contribution of specific growth conditions and community structures to variable carbon enrichment factors (Ɛ- carbon ) values for the degradation of chlorinated ethenes (CEs) by a bacterial consortium with multiple dechlorinating genes. Ɛ- carbon values for trichloroethylene, cis-1,2-dichloroethylene, and vinyl chloride were -7.24% ± 0.59%, -14.6% ± 1.71%, and -21.1% ± 1.14%, respectively, during their degradation by a microbial consortium containing multiple dechlorinating genes including tceA and vcrA. The Ɛ- carbon values of all CEs were not greatly affected by changes in growth conditions and community structures, which directly or indirectly affected reductive dechlorination of CEs by this consortium. Stability analysis provided evidence that the presence of multiple dechlorinating genes within a microbial consortium had little effect on carbon isotope fractionation, as long as the genes have definite, non-overlapping functions. Copyright © 2018 Elsevier Ltd. All rights reserved.

Academic Decision Making: The Consortium of Knox, Franklin and Monmouth Colleges; Volumes I and II. Final Report.

ERIC Educational Resources Information Center

Melville, George L.

This consortium of liberal arts colleges was instrumental in developing and coordinating their research capability through data processing. Forty research and academic development projects were undertaken. Of special importance: The Pass-Fail System, Study Habits in the Three-three calendar, Changing Trends in Attrition, The Weighing of High…

75 FR 24972 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Network Centric...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-06

... Production Act of 1993--Network Centric Operations Industry Consortium, Inc. Notice is hereby given that, on..., 15 U.S.C. 4301 et seq. (``the Act''), Network Centric Operations Industry Consortium, Inc. (``NCOIC... venture. No other changes have been made in either the membership or planned activity of the group...

75 FR 8116 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Network Centric...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... Production Act of 1993--Network Centric Operations Industry Consortium, Inc. Notice is hereby given that, on..., 15 U.S.C. 4301 et seq. (``the Act'') Network Centric Operations Industry Consortium, Inc. has filed... venture. No other changes have been made in either the membership or planned activity of the group...

77 FR 34066 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Network Centric...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-08

... Production Act of 1993--Network Centric Operations Industry Consortium, Inc. Notice is hereby given that, on..., 15 U.S.C. 4301 et seq. (``the Act''), Network Centric Operations Industry Consortium, Inc. (``NCOIC... changes have been made in either the membership or planned activity of the group research project...

Eisenhower Pre-Service Teacher Education Project, Higher Education Consortium Region III. Final Report.

ERIC Educational Resources Information Center

Wozniak, Jacci

The Eisenhower Pre-Service Teacher Education Project was developed by the University of Central Florida, the five community colleges in Region III of the Higher Education Consortium, and the private college and universities in the same region to design curriculum changes to improve the preparation of elementary and secondary math and science…

Project COMPAS [Consortium for Operating and Managing Programs for the Advancment of Skills]: A Design for Change.

ERIC Educational Resources Information Center

Schermerhorn, Leora L., Ed.; And Others

Descriptive and evaluative information is provided in this report on Project COMPAS (Consortium for Operating and Managing Programs for the Advancement of Skills), a cooperative effort between seven community colleges which developed cognitive skills programs for entry-level freshmen. Chapter I reviews the unique features of Project COMPAS,…

Healthy Brain Development: Precursor to Learning. National Health/Education Consortium (1st, Baltimore, Maryland, December 6, 1990).

ERIC Educational Resources Information Center

Institute for Educational Leadership, Washington, DC.

This report presents the proceedings of a consortium at which leading developmental neuroscientists from across the United States and Canada met at Johns Hopkins University to explore the relationship between children's health and learning and to propose policy changes. Early brain development and its relationship to intelligence, learning, and…

The STRONG STAR Multidisciplinary PTSD Research Consortium

DTIC Science & Technology

2013-09-01

prenatal corticosterone exposure mimics the effects of prenatal stress on adult brain stress response systems and fear extinction behavior...stress, prenatal corticosterone reduced TH mRNA, suggesting that prenatal stress produces its effects on TH mRNA through a mechanism dependent on...Exogenous prenatal corticosterone exposure mimics the effects of prenatal stress on adult brain stress response systems and fear extinction behavior

Military Suicide Research Consortium

DTIC Science & Technology

2015-10-01

physical and sexual abuse and lifetime number of suicide attempts: A persistent and theoretically important relationship. Behaviour Research & Therapy ...meeting of the Association of Behavioral and Cognitive Therapies , Chicago, IL. Norr, A. M., Allan, N. P., Macatee, R. J., Capron, D. W., & Schmidt, N. B...presentation to the annual Association for Behavioral and Cognitive Therapies conference, Chicago, IL. >>Dr. Craig Bryan had the following: Bryan, C.J

Reuse at the Software Productivity Consortium

NASA Technical Reports Server (NTRS)

Weiss, David M.

1989-01-01

The Software Productivity Consortium is sponsored by 14 aerospace companies as a developer of software engineering methods and tools. Software reuse and prototyping are currently the major emphasis areas. The Methodology and Measurement Project in the Software Technology Exploration Division has developed some concepts for reuse which they intend to develop into a synthesis process. They have identified two approaches to software reuse: opportunistic and systematic. The assumptions underlying the systematic approach, phrased as hypotheses, are the following: the redevelopment hypothesis, i.e., software developers solve the same problems repeatedly; the oracle hypothesis, i.e., developers are able to predict variations from one redevelopment to others; and the organizational hypothesis, i.e., software must be organized according to behavior and structure to take advantage of the predictions that the developers make. The conceptual basis for reuse includes: program families, information hiding, abstract interfaces, uses and information hiding hierarchies, and process structure. The primary reusable software characteristics are black-box descriptions, structural descriptions, and composition and decomposition based on program families. Automated support can be provided for systematic reuse, and the Consortium is developing a prototype reuse library and guidebook. The software synthesis process that the Consortium is aiming toward includes modeling, refinement, prototyping, reuse, assessment, and new construction.

A History of the Liberal Arts Computer Science Consortium and Its Model Curricula

ERIC Educational Resources Information Center

Bruce, Kim B.; Cupper, Robert D.; Scot Drysdale, Robert L.

2010-01-01

With the support of a grant from the Sloan Foundation, nine computer scientists from liberal arts colleges came together in October, 1984 to form the Liberal Arts Computer Science Consortium (LACS) and to create a model curriculum appropriate for liberal arts colleges. Over the years the membership has grown and changed, but the focus has remained…

Sea Changes in Social Science Education: Woods Hole 2000. The Social Science Education Consortium Conference Series.

ERIC Educational Resources Information Center

White, Charles S., Ed.

The agenda for the Social Science Education Consortium conference at Woods Hole (Massachusetts) was designed to continue a tradition of examining scholarship relative to the social sciences in K-12 education. The content focus for this volume, is political science, economics, and sociology. Following a "Foreword" (Matthew T. Downey; Joseph P.…

Military Suicide Research Consortium: Extension to New Opportunities and Challenges

DTIC Science & Technology

2017-04-01

Abnormal Psychology . 56. Tucker, R., Michaels, M., Rogers, M., Wingate, L., & Joiner, T. (2016). Construct validity of a proposed new diagnostic entity...analysis with implications for understanding suicidal behavior. Journal of Abnormal Psychology , 123, 835-840. 2. Anestis, M., Soberay, K., Gutierrez, P...predictions of the interpersonal- psychological theory of suicidal behavior: Empirical tests in two samples of young adults. Journal of Abnormal

Military Suicide Research Consortium

DTIC Science & Technology

2016-10-01

just prior to the time of death: An analysis with implications for understanding suicidal behavior. Journal of Abnormal Psychology , 124(2), 460-461...suicidal behavior. Journal of Abnormal Psychology , 123(4), 835-840. doi: 10.1037/a0037480 Johnson, L. L., O’Connor, S.S., Kaminer, B., Jobes, D. A...Journal of Clinical and Consulting Psychology ; Journal of Abnormal Psychology ; International Journal of Psychology ; Archives of Suicide Research

From vision to reality--managing change in the provision of library and information services to nurses, midwives, health visitors and PAMs: (professions allied to medicine) a case study of the North Thames experience with the Inner London Consortium.

PubMed

Godbolt, S; Williamson, J; Wilson, A

1997-06-01

One of the North Thames' pioneering consortia, the Inner London Consortium (ILC) is a complex body which includes NHS Trusts with teaching hospital university connections, community-based Trusts and general hospital acute Trusts. Within the consortium there are 12,000 trained nurses, midwives, health visitors and other professional staff working in the professions allied to medicine (PAMs), all of whom require access to and provision of appropriate library information services. In 1994, taking into account experiences elsewhere in the Region and nationally, it became clear that library issues were complex and would become acute with the move of nursing libraries from ILC Trust sites over a very short timescale. A report on the issues commissioned by the Consortium recommended that a library project, which built on existing NHS Trust PGMDE funded library resources and moved these to a multidisciplinary base to serve the consortium membership, be implemented. The objective of providing access to library information services for nurses and PAMs was achieved. Successes that emerged from the implementation included: The registration in Trust libraries of almost 12 000 new members within the initial 6-month monitoring period. The development of service level agreements and standards for the delivery of services to these new user groups. This paper describes the processes behind these significant and complex changes.

Northeast Artificial Intelligence Consortium (NAIC). Volume 9. A Planner System for the Application of Indications and Warning

DTIC Science & Technology

1990-12-01

personality of other cognitive entities in the world. POPLAR is a step towards an AI system whose behavior is psychologically justified and can provide the...natural language capability (i.e. the ver- bal behavior of 1) and 5) are not addressed). Nor do we tackle in any complete ard principled manner the...human cognitive behavior . This property makes POPLAR 1.3 personality-oriented, i.e. provision is made in the present model for introducing personality

Computer-aided injection molding system

NASA Astrophysics Data System (ADS)

Wang, K. K.; Shen, S. F.; Cohen, C.; Hieber, C. A.; Isayev, A. I.

1982-10-01

Achievements are reported in cavity-filling simulation, modeling viscoelastic effects, measuring and predicting frozen-in birefringence in molded parts, measuring residual stresses and associated mechanical properties of molded parts, and developing an interactive mold-assembly design program and an automatic NC maching data generation and verification program. The Cornell Injection Molding Program (CIMP) consortium is discussed as are computer user manuals that have been published by the consortium. Major tasks which should be addressed in future efforts are listed, including: (1) predict and experimentally determine the post-fillin behavior of thermoplastics; (2) simulate and experimentally investigate the injection molding of thermosets and filled materials; and (3) further investigate residual stresses, orientation and mechanical properties.

Duchenne Regulatory Science Consortium Meeting on Disease Progression Modeling for Duchenne Muscular Dystrophy.

PubMed

Larkindale, Jane; Abresch, Richard; Aviles, Enrique; Bronson, Abby; Chin, Janice; Furlong, Pat; Gordish-Dressman, Heather; Habeeb-Louks, Elizabeth; Henricson, Erik; Kroger, Hans; Lynn, Charles; Lynn, Stephen; Martin, Dana; Nuckolls, Glen; Rooney, William; Romero, Klaus; Sweeney, Lee; Vandenborne, Krista; Walter, Glenn; Wolff, Jodi; Wong, Brenda; McDonald, Craig M; Duchenne Regulatory Science Consortium Imaging-Dmd Consortium And The Cinrg Investigators, Members Of The

2017-01-12

The Duchenne Regulatory Science Consortium (D-RSC) was established to develop tools to accelerate drug development for DMD.  The resulting tools are anticipated to meet validity requirements outlined by qualification/endorsement pathways at both the U.S. Food and Drug Administration (FDA) and European Medicines Administration (EMA), and will be made available to the drug development community. The initial goals of the consortium include the development of a disease progression model, with the goal of creating a model that would be used to forecast changes in clinically meaningful endpoints, which would inform clinical trial protocol development and data analysis.  Methods: In April of 2016 the consortium and other experts met to formulate plans for the development of the model.  Conclusions: Here we report the results of the meeting, and discussion as to the form of the model that we plan to move forward to develop, after input from the regulatory authorities.

Performance assessment of a submerged membrane bioreactor using a novel microbial consortium.

PubMed

Chon, Kangmin; Lee, Kyungpyo; Kim, In-Soo; Jang, Am

2016-06-01

The performance of a submerged membrane bioreactor (MBR) with and without a novel microbial consortium (NMBR vs. CMBR) was compared to provide deeper insights into the effects of changes in water quality and dissolved organic matter (DOM) characteristics by a novel microbial consortium on the fouling characteristics of MBR processes. Despite similar operating conditions and identical DOM properties in the feed waters, NMBR exhibited a lower propensity to release polysaccharide-like compounds with low molecular weight by bacterial activities compared to CMBR. These compounds have a great fouling potential for MBR processes. Therefore, an increase in the transmembrane pressure (TMP) of NMBR (normalized TMP (TMP/TMP0): 1.14) was much slower and less significant than that observed in CMBR (TMP/TMP0: 2.61). These observations imply that the novel microbial consortium can efficiently mitigate membrane fouling by hydrophilic DOM in MBR processes. Copyright © 2016 Elsevier Ltd. All rights reserved.

The ARC (Astrophysical Research Consortium) telescope project.

NASA Astrophysics Data System (ADS)

Anderson, K. S.

A consortium of universities intends to construct a 3.5 meter optical-infrared telescope at a site in south-central New Mexico. The use of innovative mirror technology, a fast primary, and an alt-azimuth mounting results in a compact and lightweight instrument. This telescope will be uniquely well-suited for addressing certain observational programs by virtue of its capability for fully remote operation and rapid instrument changes.

Critical Pedagogy--The Practice with Veteran Teachers: The Work of the Eastern Pennsylvania Lead Teacher Consortium. [and] Abandon Ship, Change Course, or Ride It Out: A Reaction to Walker.

ERIC Educational Resources Information Center

Walker, Thomas J.; Johnson, Scott D.

1993-01-01

The Eastern Pennsylvania Lead Teacher Consortium, a regional network for professional development of vocational teachers, demonstrates that lead teachers' work must be tied to student learning outcomes, ideas and practices must be communicated to building-level staff, and regional consortia need a dedicated funding source. (SK)

Chemical sensing in mammalian host-bacterial commensal associations

USDA-ARS?s Scientific Manuscript database

The mammalian gastrointestinal (GI) tract is colonized by a complex consortium of bacterial species. Bacteria engage in chemical signaling to coordinate population-wide behavior. However, it is unclear if chemical sensing plays a role in establishing mammalian host–bacterial commensal relationships....

Military Suicide Research Consortium

DTIC Science & Technology

2012-10-01

J. E. (2010). Surrogate endpoints in suicide research. Suicide and Life-Threatening Behavior, 40(5), 500- 505 . doi:10.1521/suli.2010.40.5.500...symptoms (Baglioni et al., 2010)—all of which may serve to mediate the relationship between insom- nia symptoms and suicidal ideation and behavior. 3...baseline insom- nia symptom index, MSSI, BHS, PTSD, and MCMI scores. Addi- tional analyses involved a logistic regression examining the relation of

DoD Alcohol and Substance Abuse Consortium Award

DTIC Science & Technology

2016-10-01

opiate use disorder (OUD) also has developed significant clinical importance due to prolonged pain treatments with opiates. FDA approved...2) behaviors other than amount of alcohol consumed will be examined, such as anxiety-like behavior, sensitivity to pain and avoidance of an...The prospectus will be reviewed by the entire SRPP Committee and a subset of applications will be approved to develop a 10- to 20-page mini -protocol

The Presence of the Cyanobacterial Toxin Microcystin in Black Band Disease of Corals

USDA-ARS?s Scientific Manuscript database

Black band disease (BBD) of corals consists of a pathogenic consortium of microorganisms of four physiological functional groups: phototrophs, heterotrophs, sulfate reducers, and sulfide oxidizers. Together, using a combination of behavioral and physiological strategies, the members of the BBD con...

Clinicians' experiences with the fragile X clinical and research consortium.

PubMed

Liu, Jessica A; Hagerman, Randi J; Miller, Robert M; Craft, Lisa T; Finucane, Brenda; Tartaglia, Nicole; Berry-Kravis, Elizabeth M; Sherman, Stephanie L; Kidd, Sharon A; Cohen, Jeffrey

2016-12-01

The objectives of the study were to assess the attitudes and experiences of clinicians involved in a consortium of clinics serving people with fragile X-associated disorders to gauge satisfaction with the consortium and its efforts to improve quality of life for patients and the community. An internet survey was sent to 26 fragile X (FX) clinic directors participating in the Fragile X Clinical and Research Consortium (FXCRC). Respondents were asked to complete 19 questions on consortium performance and outcomes relevant for their own clinic. The response rate was 84% (22/26), with two surveys providing incomplete data. Assistance with clinic establishment, opportunities for research collaborations, and access to colleagues and information were highly valued. Approximately 76% of clinicians reported improvements in patient care and 60% reported an increase in patient services. There was a 57% increase in participation in a FX-related clinical trial among clinics since joining the FXCRC (24% vs. 81%). Overall, respondents reported primarily positive experiences from participation in the FXCRC. Common suggestions for improvement included additional financial support and increased utilization of collected patient data for research purposes. Additionally, a Clinic Services Checklist was administered annually to examine changes in services offered over time. There were several important changes regarding the provision of services by clinics, often with multiple clinics changing with respect to a service. In conclusion, the FXCRC has led to the establishment and sustainment of fragile X clinics in the U.S., fostered cooperation among fragile X clinicians, and provided clinics with a platform to share recommendations and best practices to maximize quality of life for their patients and the overall fragile X community. The results from the survey and checklist also provide suggestions to strengthen the FXCRC and enhance future collaborations among FXCRC members. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Characterization of a di-n-butyl phthalate-degrading bacterial consortium and its application in contaminated soil.

PubMed

Yang, Jing; Guo, Chuling; Liu, Shasha; Liu, Weiting; Wang, Han; Dang, Zhi; Lu, Guining

2018-04-17

Dibutyl phthalate (DBP), as a plasticizer, is widely used in China, and it is easily released into diverse environments. In this study, we have obtained a stable bacterial consortium (B1) enriched from municipal sewage treatment plant activated sludge. The obtained bacterial consortium B1 was capable of degrading DBP and was mainly composed of Pandoraea sp. and Microbacterium sp. From the initial concentrations of 35-500 mg L -1 , DBP was efficiently degraded by the consortium, with the degradation rates above 92% within 3 days. The optimal temperature for DBP degradation was 30 °C and consortium B1 could adapt to a wide range of pH (5.5-8.5). The analysis of Illumina sequencing further showed that the relative abundance of Pandoraea was increased at the beginning of the degradation, while Microbacterium was decreased. In the later stage of the degradation, the change of the relative abundance of Pandoraea and Microbacterium was opposite. Apart from DBP, consortium B1 could also utilize dimethyl phthalate (DMP), di-2-ethylhexyl phthalate (DEHP), and phthalic acid (PA) as the sole carbon. Moreover, adding B1 to DBP-contaminated soil could greatly improve the removal rate of DBP, suggesting that B1 has a great potential for the bioremediation of DBP-contaminated environments.

"Cooking the books"--behavior-based safety at the San Francisco Bay Bridge.

PubMed

Brown, Garrett D; Barab, Jordan

2007-01-01

Practitioners of Behavior-Based Safety (BBS) claim dramatic reductions in worker injuries and illnesses through modifying workers' "unsafe behaviors." This case study of a BBS program implemented by KFM, a giant construction consortium rebuilding the eastern span of the San Francisco Bay Bridge in California, documents how BBS was used to suppress reporting of worker injuries and illnesses on site. The key elements of KFM's BBS "injury prevention" strategy included: 1) cash incentives to workers and supervisors who do not report injuries; 2) reprisals and threats of reprisals against those employees who do report injuries; 3) selection and use of employer friendly occupational health clinics and workers compensation insurance administrators; 4) strict limits on the activities of contract industrial hygiene consultants; and 5) a secretive management committee that decides whether reported injuries and illnesses are legitimate and recordable. KFM reported injury and illness rates 55% to 72% lower than other bridge builders in the Bay Area, but the California Division of Occupational Safety and Health (Cal/OSHA) issued Willful citations to the consortium in June 2006 for failing to record 13 worker injuries on its "OSHA Log 300," as required by law.

The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas.

PubMed

Ecker, Joseph R; Geschwind, Daniel H; Kriegstein, Arnold R; Ngai, John; Osten, Pavel; Polioudakis, Damon; Regev, Aviv; Sestan, Nenad; Wickersham, Ian R; Zeng, Hongkui

2017-11-01

A comprehensive characterization of neuronal cell types, their distributions, and patterns of connectivity is critical for understanding the properties of neural circuits and how they generate behaviors. Here we review the experiences of the BRAIN Initiative Cell Census Consortium, ten pilot projects funded by the U.S. BRAIN Initiative, in developing, validating, and scaling up emerging genomic and anatomical mapping technologies for creating a complete inventory of neuronal cell types and their connections in multiple species and during development. These projects lay the foundation for a larger and longer-term effort to generate whole-brain cell atlases in species including mice and humans. Copyright © 2017 Elsevier Inc. All rights reserved.

Military Suicide Research Consortium (MSRC)

DTIC Science & Technology

2013-10-01

suicide research. Suicide and Life-Threatening Behavior, 40(5), 500- 505 . doi:10.1521/suli.2010.40.5.500 Breshears, R. E., Brenner, L. A., Harwood, J...mood symptoms (Baglioni et al., 2010)—all of which may serve to mediate the relationship between insom- nia symptoms and suicidal ideation and behavior...included baseline insom- nia symptom index, MSSI, BHS, PTSD, and MCMI scores. Addi- tional analyses involved a logistic regression examining the relation of

Duchenne Regulatory Science Consortium Meeting on Disease Progression Modeling for Duchenne Muscular Dystrophy

PubMed Central

Larkindale, Jane; Abresch, Richard; Aviles, Enrique; Bronson, Abby; Chin, Janice; Furlong, Pat; Gordish-Dressman, Heather; Habeeb-Louks, Elizabeth; Henricson, Erik; Kroger, Hans; Lynn, Charles; Lynn, Stephen; Martin, Dana; Nuckolls, Glen; Rooney, William; Romero, Klaus; Sweeney, Lee; Vandenborne, Krista; Walter, Glenn; Wolff, Jodi; Wong, Brenda; McDonald, Craig M.; Duchenne Regulatory Science Consortium, Imaging-DMD Consortium and the CINRG Investigators, members of the

2017-01-01

Introduction: The Duchenne Regulatory Science Consortium (D-RSC) was established to develop tools to accelerate drug development for DMD.  The resulting tools are anticipated to meet validity requirements outlined by qualification/endorsement pathways at both the U.S. Food and Drug Administration (FDA) and European Medicines Administration (EMA), and will be made available to the drug development community. The initial goals of the consortium include the development of a disease progression model, with the goal of creating a model that would be used to forecast changes in clinically meaningful endpoints, which would inform clinical trial protocol development and data analysis.  Methods: In April of 2016 the consortium and other experts met to formulate plans for the development of the model.  Conclusions: Here we report the results of the meeting, and discussion as to the form of the model that we plan to move forward to develop, after input from the regulatory authorities. PMID:28228973

Opportunities and Challenges in Using Research to Facilitate Climate Communication Collaborations

NASA Astrophysics Data System (ADS)

Akerlof, K.; Johnson, B. B.; Nackerman, C. J.; Maibach, E.

2014-12-01

Climate change represents the worst of wicked environmental problems, requiring collaborations among individuals and groups that cross public, private and voluntary sectors on a global scale to reduce greenhouse gas emissions and prepare for impacts. The Climate Communication Consortium of Maryland represents such a collaboration on a state level for the purpose of supporting governments, non-profits, businesses and universities in communicating with the public about climate and energy within the context of multiple frames, such as public health, extreme weather, and coastal resilience. The collaboration was developed using communication research as an organizational framework - providing data from yearly public opinion surveys on Marylanders' attitudes, behaviors and policy support, and a variety of other qualitative and quantitative studies. In this presentation, we will highlight four dimensions of the use of research within collaborative organizational climate communication that can lead to success, or impediments: 1) individual organizational ability and resources for using audience data; 2) the linking of research questions to programmatic development goals and processes; 3) the weighing of audience- versus communicator-oriented values and priorities; and 4) identification of overarching communication objectives that span individual organizational interests. We will illustrate these dimensions using findings from surveys of our member organizations describing the types of barriers organizations face in communicating about climate change effectively, including their use of formative and evaluative research, and will discuss some of the findings from our public opinion and experimental research, illustrating the ways in which these findings influenced programmatic development and were used by Consortium member organizations.

The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition

PubMed Central

Deutsch, Eric W.; Csordas, Attila; Sun, Zhi; Jarnuczak, Andrew; Perez-Riverol, Yasset; Ternent, Tobias; Campbell, David S.; Bernal-Llinares, Manuel; Okuda, Shujiro; Kawano, Shin; Moritz, Robert L.; Carver, Jeremy J.; Wang, Mingxun; Ishihama, Yasushi; Bandeira, Nuno; Hermjakob, Henning; Vizcaíno, Juan Antonio

2017-01-01

The ProteomeXchange (PX) Consortium of proteomics resources (http://www.proteomexchange.org) was formally started in 2011 to standardize data submission and dissemination of mass spectrometry proteomics data worldwide. We give an overview of the current consortium activities and describe the advances of the past few years. Augmenting the PX founding members (PRIDE and PeptideAtlas, including the PASSEL resource), two new members have joined the consortium: MassIVE and jPOST. ProteomeCentral remains as the common data access portal, providing the ability to search for data sets in all participating PX resources, now with enhanced data visualization components. We describe the updated submission guidelines, now expanded to include four members instead of two. As demonstrated by data submission statistics, PX is supporting a change in culture of the proteomics field: public data sharing is now an accepted standard, supported by requirements for journal submissions resulting in public data release becoming the norm. More than 4500 data sets have been submitted to the various PX resources since 2012. Human is the most represented species with approximately half of the data sets, followed by some of the main model organisms and a growing list of more than 900 diverse species. Data reprocessing activities are becoming more prominent, with both MassIVE and PeptideAtlas releasing the results of reprocessed data sets. Finally, we outline the upcoming advances for ProteomeXchange. PMID:27924013

Next Steps for Research on SACD Programs: Embracing Complexity

ERIC Educational Resources Information Center

Atkins, Marc S.; Shernoff, Elisa S.; Marinez-Lora, Ane

2009-01-01

This commentary focuses on the promises and challenges facing the Social and Character Development (SACD) consortium in evaluating the effectiveness of seven universal SACD programs designed to enhance student behavior and school climate under conditions of real world practice. In this commentary, we highlight that the opportunity costs associated…

Collegiality or Strategic Compromise? A New Era in Admission Consortia

ERIC Educational Resources Information Center

Barnes, Bradley

2012-01-01

This case study examines the collegial behavior of enrollment professionals within an admission consortium. Resource Dependency Theory provides a guiding framework for the analysis and discussion of the findings. Data collection for this case study was derived from interviews with enrollment deans and directors who represent public universities…

Effects of Leadership on Student Success through the Balanced Leadership Framework

ERIC Educational Resources Information Center

Cetin, Munevver; Kinik, F. Sehkar F.

2016-01-01

Attempts have been made to identify behavior patterns peculiar to leadership by many institutions and organizations; also numerous studies have been conducted in this area. Of all these organizations, The Interstate School Leaders Licensure Consortium (ISLLC) identifies the definitive standards of school leadership. Examining these standards in…

Experience of the Paris Research Consortium Climate-Environment-Society

NASA Astrophysics Data System (ADS)

Joussaume, Sylvie; Pacteau, Chantal; Vanderlinden, Jean Paul

2016-04-01

It is now widely recognized that the complexity of climate change issues translates itself into a need for interdisciplinary approaches to science. This allows to first achieve a more comprehensive vision of climate change and, second, to better inform the decision-making processes. However, it seems that willingness alone is rarely enough to implement interdisciplinarity. The purpose of this presentation is to mobilize reflexivity to revisit and analyze the experience of the Paris Consortium for Climate-Environment-Society. The French Consortium Climate-Environment-Society aims to develop, fund and coordinate interdisciplinary research into climate change and its impacts on society and environment. Launched in 2007, the consortium relies on the research expertise of 17 laboratories and federation in the Paris area working mainly in the fields of climatology, hydrology, ecology, health sciences, and the humanities and social sciences. As examples, economists and climatologists have studied greenhouse gas emission scenarios compatible with climate stabilization goals. Historical records have provided both knowledge about past climate change and vulnerability of societies. Some regions, as the Mediterranean and the Sahel, are particularly vulnerable and already have to cope with water availability, agricultural production and even health issues. A project showed that millet production in West Africa is expected to decline due to warming in a higher proportion than observed in recent decades. Climate change also raises many questions concerning health: combined effects of warming and air quality, impacts on the production of pollens and allergies, impacts on infectious diseases. All these issues lead to a need for approaches integrating different disciplines. Furthermore, climate change impacts many ecosystems which, in turn, affect its evolution. Our experience shows that interdisciplinarity supposes, in order to take shape, the conjunction between programming choices, supporting this kind of approach, and autonomy given to experimenting with interdisciplinary practices. The interdisciplinary approach does not put itself in place and requires a collective reflection on the objectives and practices. Many tools exist to support this process, in particular to mature interdisciplinarity. This incubation period allows the various disciplines to learn to know each other and to build a common conceptual and methodological basis.

Pre-test probability of obstructive coronary stenosis in patients undergoing coronary CT angiography: Comparative performance of the modified diamond-Forrester algorithm versus methods incorporating cardiovascular risk factors.

PubMed

Ferreira, António Miguel; Marques, Hugo; Tralhão, António; Santos, Miguel Borges; Santos, Ana Rita; Cardoso, Gonçalo; Dores, Hélder; Carvalho, Maria Salomé; Madeira, Sérgio; Machado, Francisco Pereira; Cardim, Nuno; de Araújo Gonçalves, Pedro

2016-11-01

Current guidelines recommend the use of the Modified Diamond-Forrester (MDF) method to assess the pre-test likelihood of obstructive coronary artery disease (CAD). We aimed to compare the performance of the MDF method with two contemporary algorithms derived from multicenter trials that additionally incorporate cardiovascular risk factors: the calculator-based 'CAD Consortium 2' method, and the integer-based CONFIRM score. We assessed 1069 consecutive patients without known CAD undergoing coronary CT angiography (CCTA) for stable chest pain. Obstructive CAD was defined as the presence of coronary stenosis ≥50% on 64-slice dual-source CT. The three methods were assessed for calibration, discrimination, net reclassification, and changes in proposed downstream testing based upon calculated pre-test likelihoods. The observed prevalence of obstructive CAD was 13.8% (n=147). Overestimations of the likelihood of obstructive CAD were 140.1%, 9.8%, and 18.8%, respectively, for the MDF, CAD Consortium 2 and CONFIRM methods. The CAD Consortium 2 showed greater discriminative power than the MDF method, with a C-statistic of 0.73 vs. 0.70 (p<0.001), while the CONFIRM score did not (C-statistic 0.71, p=0.492). Reclassification of pre-test likelihood using the 'CAD Consortium 2' or CONFIRM scores resulted in a net reclassification improvement of 0.19 and 0.18, respectively, which would change the diagnostic strategy in approximately half of the patients. Newer risk factor-encompassing models allow for a more precise estimation of pre-test probabilities of obstructive CAD than the guideline-recommended MDF method. Adoption of these scores may improve disease prediction and change the diagnostic pathway in a significant proportion of patients. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Brain-Immune Interactions as the Basis of Gulf War Illness: Consortium Development

DTIC Science & Technology

2012-12-01

advancements regarding the role of glia in chronic pain processing (Watkins et al., 2007; Watkins et al., 2009), axonal transport deficits in...cytokine signaling) Behavioral Effects (fatigue, pain , cognitive problems) Astrocyte Activation (cytokine signaling) mutually exclusive and once...K. Sullivan, Ph.D. 12 characterized by persistent pain , cognitive dysfunction, and fatigue

Religiosity and Health Behavior--What Does Research Tell Us?

ERIC Educational Resources Information Center

Young, Michael

2011-01-01

This article is based on the AAHPERD Research Consortium Scholar Lecture delivered at the 2010 AAHPERD National Convention in Indianapolis, Indiana. Dr. Young's various projects are five-time winners of the U.S. Department of Health & Human Services Award for Outstanding Work in Community Health Promotion. His drug education program, Keep A Clear…

Semisolid Metal Processing Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Apelian,Diran

Mathematical modeling and simulations of semisolid filling processes remains a critical issue in understanding and optimizing the process. Semisolid slurries are non-Newtonian materials that exhibit complex rheological behavior. There the way these slurries flow in cavities is very different from the way liquid in classical casting fills cavities. Actually filling in semisolid processing is often counter intuitive

AAHPER Research Consortium Symposium Papers: Socio-Psychological Dimensions, Research Design and Safety. Volume II, Book 3.

ERIC Educational Resources Information Center

Cox, Richard H., Ed.

This collection focuses on research topics in physical education and athletics and includes the following papers: Methodological Problems in the Assessment of Personality from the Psychoanalytic, Behavioral and Cognitive Positions; Some Factors Affecting the Performance of Women in Sports and Activity; Multivariate Considerations in Children's…

New Learning Programs in Cognitive Vitality, Alzheimer's Disease, and Related Dementias

ERIC Educational Resources Information Center

Kovacich, Joann; Garrett, Ruth; Forti, Esther M.

2006-01-01

As the population continues to age there remains an unmet need in preventing, identifying, treating, and managing mental/behavioral health problems among older adults. The purpose of this paper is to describe educational and training programs offered through three Geriatric Education Centers: (1) the Meharry Consortium Geriatric Education Center,…

Roll-to-Roll Advanced Materials Manufacturing DOE Lab Consortium - FY16 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniel, Claus; Wood, III, David L.; Krumdick, Gregory

2016-12-01

A DOE laboratory consortium comprised of ORNL, ANL, NREL and LBNL, coordinating with Kodak’s Eastman Business Park (Kodak) and other selected industry partners, was formed to address enhancing battery electrode performance and R2R manufacturing challenges. The objective of the FY 2016 seed project was to develop a materials genome synthesis process amenable to R2R manufacturing and to provide modeling, simulation, processing, and manufacturing techniques that demonstrate the feasibility of process controls and scale-up potential for improved battery electrodes. The research efforts were to predict and measure changes and results in electrode morphology and performance based on process condition changes; tomore » evaluate mixed, active, particle size deposition and drying for novel electrode materials; and to model various process condition changes and the resulting morphology and electrode performance.« less

Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study

PubMed Central

Rebuli, Meghan E.; Camacho, Luísa; Adonay, Maria E.; Reif, David M.; Aylor, David L.; Patisaul, Heather B.

2015-01-01

Bisphenol A (BPA) is a high volume production chemical and has been identified as an endocrine disruptor, prompting concern that developmental exposure could impact brain development and behavior. Rodent and human studies suggest that early life BPA exposure may result in an anxious, hyperactive phenotype but results are conflicting and data from studies using multiple doses below the no-observed-adverse-effect level are limited. To address this, the present studies were conducted as part of the CLARITY-BPA (Consortium Linking Academic and Regulatory Insights on BPA Toxicity) program. The impact of perinatal BPA exposure (2.5, 25, or 2500 µg/kg body weight (bw)/day) on behaviors related to anxiety and exploratory activity was assessed in juvenile (prepubertal) and adult NCTR Sprague-Dawley rats of both sexes. Ethinyl estradiol (0.5 µg/kg bw/day) was used as a reference estrogen. Exposure spanned gestation and lactation with dams gavaged from gestational day 6 until birth and then the offspring gavaged directly through weaning (n = 12/sex/group). Behavioral assessments included open field, elevated plus maze, and zero maze. Anticipated sex differences in behavior were statistically identified or suggested in most cases. No consistent effects of BPA were observed for any endpoint, in either sex, at either age compared to vehicle controls; however, significant differences between BPA-exposed and ethinyl estradiol-exposed groups were identified for some endpoints. Limitations of this study are discussed and include suboptimal statistical power and low concordance across behavioral tasks. These data do not indicate BPA-related effects on anxiety or exploratory activity in these developmentally exposed rats. PMID:26209558

Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study

PubMed Central

Arambula, Sheryl E.; Belcher, Scott M.; Planchart, Antonio; Turner, Stephen D.

2016-01-01

Bisphenol A (BPA) is an endocrine disrupting, high volume production chemical found in a variety of products. Evidence of prenatal exposure has raised concerns that developmental BPA may disrupt sex-specific brain organization and, consequently, induce lasting changes on neurophysiology and behavior. We and others have shown that exposure to BPA at doses below the no-observed-adverse-effect level can disrupt the sex-specific expression of estrogen-responsive genes in the neonatal rat brain including estrogen receptors (ERs). The present studies, conducted as part of the Consortium Linking Academic and Regulatory Insights of BPA Toxicity program, expanded this work by examining the hippocampal and hypothalamic transcriptome on postnatal day 1 with the hypothesis that genes sensitive to estrogen and/or sexually dimorphic in expression would be altered by prenatal BPA exposure. NCTR Sprague-Dawley dams were gavaged from gestational day 6 until parturition with BPA (0-, 2.5-, 25-, 250-, 2500-, or 25 000-μg/kg body weight [bw]/d). Ethinyl estradiol was used as a reference estrogen (0.05- or 0.5-μg/kg bw/d). Postnatal day 1 brains were microdissected and gene expression was assessed with RNA-sequencing (0-, 2.5-, and 2500-μg/kg bw BPA groups only) and/or quantitative real-time PCR (all exposure groups). BPA-related transcriptional changes were mainly confined to the hypothalamus. Consistent with prior observations, BPA induced sex-specific effects on hypothalamic ERα and ERβ (Esr1 and Esr2) expression and hippocampal and hypothalamic oxytocin (Oxt) expression. These data demonstrate prenatal BPA exposure, even at doses below the current no-observed-adverse-effect level, can alter gene expression in the developing brain. PMID:27571134

Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study.

PubMed

Arambula, Sheryl E; Belcher, Scott M; Planchart, Antonio; Turner, Stephen D; Patisaul, Heather B

2016-10-01

Bisphenol A (BPA) is an endocrine disrupting, high volume production chemical found in a variety of products. Evidence of prenatal exposure has raised concerns that developmental BPA may disrupt sex-specific brain organization and, consequently, induce lasting changes on neurophysiology and behavior. We and others have shown that exposure to BPA at doses below the no-observed-adverse-effect level can disrupt the sex-specific expression of estrogen-responsive genes in the neonatal rat brain including estrogen receptors (ERs). The present studies, conducted as part of the Consortium Linking Academic and Regulatory Insights of BPA Toxicity program, expanded this work by examining the hippocampal and hypothalamic transcriptome on postnatal day 1 with the hypothesis that genes sensitive to estrogen and/or sexually dimorphic in expression would be altered by prenatal BPA exposure. NCTR Sprague-Dawley dams were gavaged from gestational day 6 until parturition with BPA (0-, 2.5-, 25-, 250-, 2500-, or 25 000-μg/kg body weight [bw]/d). Ethinyl estradiol was used as a reference estrogen (0.05- or 0.5-μg/kg bw/d). Postnatal day 1 brains were microdissected and gene expression was assessed with RNA-sequencing (0-, 2.5-, and 2500-μg/kg bw BPA groups only) and/or quantitative real-time PCR (all exposure groups). BPA-related transcriptional changes were mainly confined to the hypothalamus. Consistent with prior observations, BPA induced sex-specific effects on hypothalamic ERα and ERβ (Esr1 and Esr2) expression and hippocampal and hypothalamic oxytocin (Oxt) expression. These data demonstrate prenatal BPA exposure, even at doses below the current no-observed-adverse-effect level, can alter gene expression in the developing brain.

Quality assurance in European pharmacy education and training*

PubMed Central

Guimarāes Morais, Jose A.; Cavaco, Afonso M.; Rombaut, Bart; Rouse, Michael J.; Atkinson, Jeffrey

A survey of quality assurance (QA) systems in European faculties of pharmacy was carried out under the auspices of the European Association of Faculties of Pharmacy PHARMINE consortium. A questionnaire based on the quality criteria of the International Pharmaceutical Federation and the Accreditation Council for Pharmacy Education (USA) was sent out to European faculties. Replies were obtained from 28 countries. Just above half has a working QA system. QA scores were high concerning matters such as complete curriculum and training, use of European Credit Transfer System, students’ representation and promotion of professional behavior. QA scores were low concerning matters such as evaluation of achievement of mission and goals, and financial resources. The PHARMINE consortium now has a basis upon which to elaborate and promote QA in European pharmacy faculties. PMID:24198856

The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins

PubMed Central

McNulty, Nathan P.; Yatsunenko, Tanya; Hsiao, Ansel; Faith, Jeremiah J.; Muegge, Brian D.; Goodman, Andrew L.; Henrissat, Bernard; Oozeer, Raish; Cools-Portier, Stéphanie; Gobert, Guillaume; Chervaux, Christian; Knights, Dan; Lozupone, Catherine A.; Knight, Rob; Duncan, Alexis E.; Bain, James R.; Muehlbauer, Michael J.; Newgard, Christopher B.; Heath, Andrew C.; Gordon, Jeffrey I.

2012-01-01

Understanding how the human gut microbiota and host are impacted by probiotic bacterial strains requires carefully controlled studies in humans and in mouse models of the gut ecosystem where potentially confounding variables that are difficult to control in humans can be constrained. Therefore, we characterized the fecal microbiomes and metatranscriptomes of adult female monozygotic twin pairs through repeated sampling 4 weeks prior to, 7 weeks during, and 4 weeks following consumption of a commercially available fermented milk product (FMP) containing a consortium of Bifidobacterium animalis subsp. lactis, two strains of Lactobacillus delbrueckii subsp. bulgaricus, Lactococcus lactis subsp. cremoris, and Streptococcus thermophilus. In addition, gnotobiotic mice harboring a 15-species model human gut microbiota whose genomes contain 58,399 known or predicted protein-coding genes were studied prior to and after gavage with all five sequenced FMP strains. No significant changes in bacterial species composition or in the proportional representation of genes encoding known enzymes were observed in the feces of humans consuming the FMP. Only minimal changes in microbiota configuration were noted in mice following single or repeated gavage with the FMP consortium. However, RNA-Seq analysis of fecal samples and follow-up mass spectrometry of urinary metabolites disclosed that introducing the FMP strains into mice results in significant changes in expression of microbiome-encoded enzymes involved in numerous metabolic pathways, most prominently those related to carbohydrate metabolism. B. animalis subsp. lactis, the dominant persistent member of the FMP consortium in gnotobiotic mice, upregulates a locus in vivo that is involved in the catabolism of xylooligosaccharides, a class of glycans widely distributed in fruits, vegetables and other foods, underscoring the importance of these sugars to this bacterial species. The human fecal metatranscriptome exhibited significant changes, confined to the period of FMP consumption, that mirror changes in gnotobiotic mice, including those related to plant polysaccharide metabolism. These experiments illustrate a translational research pipeline for characterizing the effects of fermented milk products on the human gut microbiome. PMID:22030749

Promotores As Advocates for Community Improvement: Experiences of the Western States REACH Su Comunidad Consortium.

PubMed

Kutcher, Rachel; Moore-Monroy, Martha; Bello, Elizur; Doyle, Seth; Ibarra, Jorge; Kunz, Susan; Munoz, Rocio; Patton-Lopez, Megan; Sharkey, Joseph R; Wilger, Susan; Alfero, Charlie

2015-01-01

The REACH Su Comunidad Consortium worked with 10 communities to address disparities in access to healthy food and physical activity opportunities among Hispanic populations through policy, systems, and environmental (PSE) strategies. Community health workers took leadership roles in the implementation of PSE strategies in partnership with local multisector coalitions. This article describes the role of community health workers in PSE change, the technical and professional development support provided to the REACH Su Comunidad Communities, and highlights professional development needs of community health workers engaging in PSE strategies.

Physical activity staging distribution: establishing a heuristic using multiple studies.

PubMed

Nigg, C; Hellsten, L; Norman, G; Braun, L; Breger, R; Burbank, P; Coday, M; Elliot, D; Garber, C; Greaney, M; Keteyian, S; Lees, F; Matthews, C; Moe, E; Resnick, B; Riebe, D; Rossi, J; Toobert, D; Wang, T; Welk, G; Williams, G

2005-04-01

The purpose of this study was to identify the population prevalence across the stages of change (SoC) for regular physical activity and to establish the prevalence of people at risk. With support from the National Institutes of Health, the American Heart Association, and the Robert Wood Johnson Foundation, nine Behavior Change Consortium studies with a common physical activity SoC measure agreed to collaborate and share data. The distribution pattern identified in these predominantly reactively recruited studies was Precontemplation (PC) = 5% (+/- 10), Contemplation (C) = 10% (+/- 10), Preparation (P) = 40% (+/- 10), Action = 10% (+/- 10), and Maintenance = 35% (+/- 10). With reactively recruited studies, it can be anticipated that there will be a higher percentage of the sample that is ready to change and a greater percentage of currently active people compared to random representative samples. The at-risk stage distribution (i.e., those not at criteria or PC, C, and P) was approximately 10% PC, 20% C, and 70% P in specific samples and approximately 20% PC, 10% C, and 70% P in the clinical samples. Knowing SoC heuristics can inform public health practitioners and policymakers about the population's motivation for physical activity, help track changes over time, and assist in the allocation of resources.

Military Suicide Research Consortium

DTIC Science & Technology

2013-10-01

In S . C. Horswill (Chr.), Identifying and treating predispositional variables in the development of PTSD. Symposium submitted for the Annual meeting...of a Targeted Computerized Intervention for Anxiety Sensitivity Cognitive Concerns for use with at-risk Military Populations. Individual oral...Zvolensky, M.J. (2012). Daily marijuana use and suicidality: The unique impact of social anxiety . Addictive Behaviors, 37, 387-392. 8. Capron, D

Rapid Mineralization of Benzo[a]pyrene by a Microbial Consortium Growing on Diesel Fuel

PubMed Central

Kanaly, Robert A.; Bartha, Richard; Watanabe, Kazuya; Harayama, Shigeaki

2000-01-01

A microbial consortium which rapidly mineralized the environmentally persistent pollutant benzo[a]pyrene was recovered from soil. The consortium cometabolically converted [7-14C]benzo[a]pyrene to 14CO2 when it was grown on diesel fuel, and the extent of benzo[a]pyrene mineralization was dependent on both diesel fuel and benzo[a]pyrene concentrations. Addition of diesel fuel at concentrations ranging from 0.007 to 0.2% (wt/vol) stimulated the mineralization of 10 mg of benzo[a]pyrene per liter 33 to 65% during a 2-week incubation period. When the benzo[a]pyrene concentration was 10 to 100 mg liter−1 and the diesel fuel concentration was 0.1% (wt/vol), an inoculum containing 1 mg of cell protein per liter (small inoculum) resulted in mineralization of up to 17.2 mg of benzo[a]pyrene per liter in 16 days. This corresponded to 35% of the added radiolabel when the concentration of benzo[a]pyrene was 50 mg liter−1. A radiocarbon mass balance analysis recovered 25% of the added benzo[a]pyrene solubilized in the culture suspension prior to mineralization. Populations growing on diesel fuel most likely promoted emulsification of benzo[a]pyrene through the production of surface-active compounds. The consortium was also analyzed by PCR-denaturing gradient gel electrophoresis of 16S rRNA gene fragments, and 12 dominant bands, representing different sequence types, were detected during a 19-day incubation period. The onset of benzo[a]pyrene mineralization was compared to changes in the consortium community structure and was found to correlate with the emergence of at least four sequence types. DNA from 10 sequence types were successfully purified and sequenced, and that data revealed that eight of the consortium members were related to the class Proteobacteria but that the consortium also included members which were related to the genera Mycobacterium and Sphingobacterium. PMID:11010861

Understanding Kombucha Tea Fermentation: A Review.

PubMed

Villarreal-Soto, Silvia Alejandra; Beaufort, Sandra; Bouajila, Jalloul; Souchard, Jean-Pierre; Taillandier, Patricia

2018-03-01

Kombucha is a beverage of probable Manchurian origins obtained from fermented tea by a microbial consortium composed of several bacteria and yeasts. This mixed consortium forms a powerful symbiosis capable of inhibiting the growth of potentially contaminating bacteria. The fermentation process also leads to the formation of a polymeric cellulose pellicle due to the activity of certain strains of Acetobacter sp. The tea fermentation process by the microbial consortium was able to show an increase in certain biological activities which have been already studied; however, little information is available on the characterization of its active components and their evolution during fermentation. Studies have also reported that the use of infusions from other plants may be a promising alternative. Kombucha is a traditional fermented tea whose consumption has increased in the recent years due to its multiple functional properties such as anti-inflammatory potential and antioxidant activity. The microbiological composition of this beverage is quite complex and still more research is needed in order to fully understand its behavior. This study comprises the chemical and microbiological composition of the tea and the main factors that may affect its production. © 2018 Institute of Food Technologists®.

Diagnosis and Management of Behavioral Issues in Frontotemporal Dementia

PubMed Central

Manoochehri, Masood; Huey, Edward D.

2012-01-01

Frontotemporal lobar degeneration (FTLD) is an umbrella term for several different disorders. In behavioral variant frontotemporal dementia (bvFTD), patients show deterioration in cognition and social behavior. New diagnostic criteria proposed by the International Behavioral Variant FTD Consortium provide greater sensitivity in diagnosing bvFTD. Current pharmacological management of symptoms relies on medications borrowed from treating Alzheimer’s Disease (AD) and psychiatric disorders. The evidence for using AD medications such as acetylcholinesterase inhibitors is questionable. Psychiatric medications can be helpful. Trazodone or SSRIs can have some efficacy in reducing disinhibition, repetitive behaviors, sexually inappropriate behaviors, and hyperorality. Small doses of atypical antipsychotics may be helpful in decreasing agitation and verbal outbursts. Non-pharmacological management includes caregiver education and support and behavioral interventions. While symptomatic treatments are likely to remain important behavior management tools, targeting the underlying pathology of bvFTD with disease-modifying agents will hopefully be the future of treatment. PMID:22847063

Developing a statewide nursing consortium, island style.

PubMed

Magnussen, Lois; Niederhauser, Victoria; Ono, Charlene K; Johnson, Nancy Katherine; Vogler, Joyce; Ceria-Ulep, Clementina D

2013-02-01

This article describes the transformational changes in the scope and pedagogy of nursing education within a state university system through the development of the Hawaii Statewide Nursing Consortium (HSNC) curriculum. Modeled after the Oregon Consortium for Nursing Education, the HSNC used a community-based participatory approach to develop the curriculum to support all students within the state who are eligible to earn a baccalaureate degree. The curriculum was designed as a long-term solution to the anticipated shortage of nurses to care for Hawaii's diverse population. It is also an effort to increase capacity in schools of nursing by making the best use of resources in the delivery of a baccalaureate curriculum that offers exit opportunities after the completion of an associate degree. Finally, it provides new ways of educating students who will be better prepared to meet Hawaii's health needs. Copyright 2013, SLACK Incorporated.

Standardized End Point Definitions for Coronary Intervention Trials: The Academic Research Consortium-2 Consensus Document.

PubMed

Garcia-Garcia, Hector M; McFadden, Eugène P; Farb, Andrew; Mehran, Roxana; Stone, Gregg W; Spertus, John; Onuma, Yoshinobu; Morel, Marie-Angèle; van Es, Gerrit-Anne; Zuckerman, Bram; Fearon, William F; Taggart, David; Kappetein, Arie-Pieter; Krucoff, Mitchell W; Vranckx, Pascal; Windecker, Stephan; Cutlip, Donald; Serruys, Patrick W

2018-06-14

The Academic Research Consortium (ARC)-2 initiative revisited the clinical and angiographic end point definitions in coronary device trials, proposed in 2007, to make them more suitable for use in clinical trials that include increasingly complex lesion and patient populations and incorporate novel devices such as bioresorbable vascular scaffolds. In addition, recommendations for the incorporation of patient-related outcomes in clinical trials are proposed. Academic Research Consortium-2 is a collaborative effort between academic research organizations in the United States and Europe, device manufacturers, and European, US, and Asian regulatory bodies. Several in-person meetings were held to discuss the changes that have occurred in the device landscape and in clinical trials and regulatory pathways in the last decade. The consensus-based end point definitions in this document are endorsed by the stakeholders of this document and strongly advocated for clinical trial purposes. This Academic Research Consortium-2 document provides further standardization of end point definitions for coronary device trials, incorporating advances in technology and knowledge. Their use will aid interpretation of trial outcomes and comparison among studies, thus facilitating the evaluation of the safety and effectiveness of these devices.

SYNTHETIC BIOLOGY. Emergent genetic oscillations in a synthetic microbial consortium.

PubMed

Chen, Ye; Kim, Jae Kyoung; Hirning, Andrew J; Josić, Krešimir; Bennett, Matthew R

2015-08-28

A challenge of synthetic biology is the creation of cooperative microbial systems that exhibit population-level behaviors. Such systems use cellular signaling mechanisms to regulate gene expression across multiple cell types. We describe the construction of a synthetic microbial consortium consisting of two distinct cell types—an "activator" strain and a "repressor" strain. These strains produced two orthogonal cell-signaling molecules that regulate gene expression within a synthetic circuit spanning both strains. The two strains generated emergent, population-level oscillations only when cultured together. Certain network topologies of the two-strain circuit were better at maintaining robust oscillations than others. The ability to program population-level dynamics through the genetic engineering of multiple cooperative strains points the way toward engineering complex synthetic tissues and organs with multiple cell types. Copyright © 2015, American Association for the Advancement of Science.

Collaboration in a Wireless Grid Innovation Testbed by Virtual Consortium

NASA Astrophysics Data System (ADS)

Treglia, Joseph; Ramnarine-Rieks, Angela; McKnight, Lee

This paper describes the formation of the Wireless Grid Innovation Testbed (WGiT) coordinated by a virtual consortium involving academic and non-academic entities. Syracuse University and Virginia Tech are primary university partners with several other academic, government, and corporate partners. Objectives include: 1) coordinating knowledge sharing, 2) defining key parameters for wireless grids network applications, 3) dynamically connecting wired and wireless devices, content and users, 4) linking to VT-CORNET, Virginia Tech Cognitive Radio Network Testbed, 5) forming ad hoc networks or grids of mobile and fixed devices without a dedicated server, 6) deepening understanding of wireless grid application, device, network, user and market behavior through academic, trade and popular publications including online media, 7) identifying policy that may enable evaluated innovations to enter US and international markets and 8) implementation and evaluation of the international virtual collaborative process.

Intensive Intervention Practice Guide: Intensifying Check-In Check-Out for Students with or At-Risk for Emotional or Behavioral Disabilities

ERIC Educational Resources Information Center

Kunemund, Rachel; Majeika, Caitlyn; De La Cruz, Veronica Mellado; Wilkinson, Sarah

2016-01-01

The National Center for Leadership in Intensive Intervention (NCLII), a consortium funded by the Office of Special Education Programs (OSEP), prepares special education leaders to become experts in research on intensive intervention for students with disabilities who have persistent and severe academic (e.g., reading and math) and behavioral…

Study of the Successes, Pitfalls, and Outcomes of Transition Programs Working within the Consortium for Public Education

ERIC Educational Resources Information Center

Della Lucia, Eric David

2011-01-01

Transition is a concern for children moving from the eighth grade into high school. Students experience difficulty with grades, behavior, and emotional transitions at that juncture in their education. The trend can be observed both across the nation and locally in western Pennsylvania. This paper gives evidence of the national issues that students…

Military Suicide Research Consortium: Extension to New Opportunities and Challenges

DTIC Science & Technology

2017-04-01

implications for understanding suicidal behavior. Journal of Abnormal Psychology , 123(4), 835-840. doi: 10.1037/a0037480 Johnson, L. L...Consulting Psychology ; Journal of Abnormal Psychology ; International Journal of Psychology ; Archives of Suicide Research; American Journal of...Kate Nassauer, and CAPT Mike Colston, Director of the Defense Centers of Excellence for Psychological Health & Traumatic Brain Injury (DCoE) to

Military Suicide Research Consortium

DTIC Science & Technology

2014-10-01

anxiety sensitivity to reduce PTSD and depressive symptoms among civilians and veterans. In S . C. Horswill (Chr.), Identifying and treating ...marijuana use and suicidality: The unique impact of social anxiety . Addictive Behaviors, 37, 387-392. 9. Capron, D., Fitch, K., Medley, A., Blagg...Clinical Psychology, 72, 719-723. 9. Lambert, S ., McCreary, B., Preston, J., Schmidt, N.B., Joiner, T., & Ialongo, N. (2004). Anxiety sensitivity

Improvements to the Magnetics Information Consortium (MagIC) Paleo and Rock Magnetic Database

NASA Astrophysics Data System (ADS)

Jarboe, N.; Minnett, R.; Tauxe, L.; Koppers, A. A. P.; Constable, C.; Jonestrask, L.

2015-12-01

The Magnetic Information Consortium (MagIC) database (http://earthref.org/MagIC/) continues to improve the ease of data uploading and editing, the creation of complex searches, data visualization, and data downloads for the paleomagnetic, geomagnetic, and rock magnetic communities. Online data editing is now available and the need for proprietary spreadsheet software is therefore entirely negated. The data owner can change values in the database or delete entries through an HTML 5 web interface that resembles typical spreadsheets in behavior and uses. Additive uploading now allows for additions to data sets to be uploaded with a simple drag and drop interface. Searching the database has improved with the addition of more sophisticated search parameters and with the facility to use them in complex combinations. A comprehensive summary view of a search result has been added for increased quick data comprehension while a raw data view is available if one desires to see all data columns as stored in the database. Data visualization plots (ARAI, equal area, demagnetization, Zijderveld, etc.) are presented with the data when appropriate to aid the user in understanding the dataset. MagIC data associated with individual contributions or from online searches may be downloaded in the tab delimited MagIC text file format for susbsequent offline use and analysis. With input from the paleomagnetic, geomagnetic, and rock magnetic communities, the MagIC database will continue to improve as a data warehouse and resource.

Syracuse Labor/Management Consortium Workplace Literacy Skills Improvement Project. Evaluation Report.

ERIC Educational Resources Information Center

Mosenthal, Peter B.; Hinchman, Kathleen A.

An evaluation of this Syracuse, New York workplace literacy skills improvement project had three purposes: to characterize changes in the baseline performance of adults' workplace literacy skills as a function of instructional treatment; to characterize changes in workers' and supervisors' perceptions of worker effectiveness as a function of…

Changing Homeland Security: In 2010, Was Homeland Security Useful?

DTIC Science & Technology

2011-02-01

Education Consortium, September 2007). 8 James Ramsay , Daniel Cutrer, and Robert Raffel, “Development of an Outcomes-Based Undergraduate Curriculum in... Gordon , “Changing Homeland Security: Teaching the Core,” Homeland Security Affairs II, no. 1 (April 2006) http://www.hsaj.org/?article=2.1.1. 13 Kuhn

Regional Advanced Manufacturing Academy: An Agent of Change

ERIC Educational Resources Information Center

Schmeling, Daniel M.; Rose, Kevin

2010-01-01

Three Northeast Texas community colleges put aside service delivery areas and matters of "turf" to create Centers of Excellence that provided training throughout a nine county area. This consortium; along with 14 manufacturers, seven economic development corporations, and the regional workforce board, led the change in training a highly…

A preliminary investigation of forest carbon changes associated with land-use change in northern New England

Treesearch

Daolan Zheng; Linda S. Heath; Mark J. Ducey; James E. Smith

2009-01-01

Maine (ME), New Hampshire (NH), and Vermont (VT) are three of the four most heavily forested states in the United States. In these states, we examined how land-use change, at the Anderson Level I classification, affected regional forest carbon using the 30-m Multi-Resolution Land Characteristics Consortium 1992/2001 Retrofit Land Cover Change product coupled with...

Role of technology in supporting quality control and treatment fidelity in a family caregiver clinical trial.

PubMed

Farran, Carol J; Etkin, Caryn D; McCann, Judith J; Paun, Olimpia; Eisenstein, Amy R; Wilbur, Joellen

2011-11-01

This article describes how a family caregiver lifestyle physical activity clinical trial uses research technology to enhance quality control and treatment fidelity. This trial uses a range of Internet, Blaise(®) Windows-based software and Echo Server technologies to support quality control issues, such as data collection, data entry, and study management advocated by the clinical trials literature, and to ensure treatment fidelity concerning intervention implementation (i.e., design, training, delivery, receipt, and enactment) as proposed by the National Institutes of Health Behavior Change Consortium. All research staff are trained to use these technologies. Strengths of this technological approach to support quality control and treatment fidelity include the comprehensive plan, involvement of all staff, and ability to maintain accurate and timely data. Limitations include the upfront time and costs for developing and testing these technological methods, and having support staff readily available to address technological issues if they occur.

Service Modeling Language Applied to Critical Infrastructure

NASA Astrophysics Data System (ADS)

Baldini, Gianmarco; Fovino, Igor Nai

The modeling of dependencies in complex infrastructure systems is still a very difficult task. Many methodologies have been proposed, but a number of challenges still remain, including the definition of the right level of abstraction, the presence of different views on the same critical infrastructure and how to adequately represent the temporal evolution of systems. We propose a modeling methodology where dependencies are described in terms of the service offered by the critical infrastructure and its components. The model provides a clear separation between services and the underlying organizational and technical elements, which may change in time. The model uses the Service Modeling Language proposed by the W3 consortium for describing critical infrastructure in terms of interdependent services nodes including constraints, behavior, information flows, relations, rules and other features. Each service node is characterized by its technological, organizational and process components. The model is then applied to a real case of an ICT system for users authentication.

Fostering Undergraduate Research Change at the System and Consortium Level: Perspectives from the Council on Undergraduate Research

ERIC Educational Resources Information Center

Malachowski, Mitchell; Osborn, Jeffrey M.; Karukstis, Kerry K.; Ambos, Elizabeth L.; Kincaid, Shontay L.; Weiler, Daniel

2015-01-01

In this final chapter, we summarize the lessons learned from working with six systems/consortia to enhance and expand undergraduate research. The theory of change model for systems/consortia differs in significant ways from the change processes exhibited by individual institutions, offering important insights for academic leaders as they seek to…

The Climate Change Consortium of Wales (C3W)

NASA Astrophysics Data System (ADS)

Hendry, K. R.; Reis, J.; Hall, I. R.

2011-12-01

In response to the complexity and multidisciplinary nature of climate change research, the Climate Change Consortium of Wales (C3W) was formed in 2009 by the Welsh universities of Aberystwyth, Bangor, Cardiff and Swansea. Initially funded by Welsh Government, through the Higher Education Funding Council for Wales, the Countryside Council for Wales and the universities, C3W aims to bring together climate change researchers from a wide range of disciplines to explore scientific and sociological drivers, impacts and implications at local, national and international scale. The specific aims are to i) improve our fundamental understanding of the causes, nature, timing and consequences of climate change on Planet Earth's environment and on humanity, and ii) to reconfigure climate research in Wales as a recognisable centre of excellence on the world stage. In addition to improving the infrastructure for climate change research, we aim to improve communication, networking, collaborative research, and multidisciplinary data assimilation within and between the Welsh universities, and other UK and international institutions. Furthermore, C3W aims to apply its research by actively contributing towards national policy development, business development and formal and informal education activities within and beyond Wales.

Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.

PubMed

Chibnik, Lori B; Wolters, Frank J; Bäckman, Kristoffer; Beiser, Alexa; Berr, Claudine; Bis, Joshua C; Boerwinkle, Eric; Bos, Daniel; Brayne, Carol; Dartigues, Jean-Francois; Darweesh, Sirwan K L; Debette, Stephanie; Davis-Plourde, Kendra L; Dufouil, Carole; Fornage, Myriam; Grasset, Leslie; Gudnason, Vilmundur; Hadjichrysanthou, Christoforos; Helmer, Catherine; Ikram, M Arfan; Ikram, M Kamran; Kern, Silke; Kuller, Lewis H; Launer, Lenore; Lopez, Oscar L; Matthews, Fiona; Meirelles, Osorio; Mosley, Thomas; Ower, Alison; Psaty, Bruce M; Satizabal, Claudia L; Seshadri, Sudha; Skoog, Ingmar; Stephan, Blossom C M; Tzourio, Christophe; Waziry, Reem; Wong, Mei Mei; Zettergren, Anna; Hofman, Albert

2017-10-01

Several studies have reported a decline in incidence of dementia which may have large implications for the projected burden of disease, and provide important guidance to preventive efforts. However, reports are conflicting or inconclusive with regard to the impact of gender and education with underlying causes of a presumed declining trend remaining largely unidentified. The Alzheimer Cohorts Consortium aggregates data from nine international population-based cohorts to determine changes in the incidence of dementia since 1990. We will employ Poisson regression models to calculate incidence rates in each cohort and Cox proportional hazard regression to compare 5-year cumulative hazards across study-specific epochs. Finally, we will meta-analyse changes per decade across cohorts, and repeat all analysis stratified by sex, education and APOE genotype. In all cohorts combined, there are data on almost 69,000 people at risk of dementia with the range of follow-up years between 2 and 27. The average age at baseline is similar across cohorts ranging between 72 and 77. Uniting a wide range of disease-specific and methodological expertise in research teams, the first analyses within the Alzheimer Cohorts Consortium are underway to tackle outstanding challenges in the assessment of time-trends in dementia occurrence.

A Material Model for the Cyclic Behavior of Nitinol

NASA Astrophysics Data System (ADS)

Rebelo, Nuno; Zipse, Achim; Schlun, Martin; Dreher, Gael

2011-07-01

The uniaxial behavior of Nitinol in different forms and at different temperatures has been well documented in the literature. Mathematical models for the three-dimensional behavior of this class of materials, covering superelasticity, plasticity, and shape memory effects have been previously developed. Phenomenological models embedded in FEA analysis are part of common practice today in the development of devices made out of Nitinol. In vivo loading of medical devices has cyclic characteristics. There have been some indications in the literature that cyclic loading of Nitinol modifies substantially its behavior. A consortium of several stent manufacturers, Safe Technology and Dassault Systèmes Simulia Corp., dedicated to the development of fatigue laws suitable for life prediction of Nitinol devices, has conducted an extensive experimental study of the modifications in uniaxial behavior of both Nitinol wire and tubing due to cyclic loading. The Abaqus Nitinol material model has been extended to capture some of the phenomena observed and is described in this article. Namely, a preload beyond 6% strain alters the transformation plateaus; if the cyclic load amplitude is large enough, permanent deformations (residual martensite) are observed; the lower plateau increases; and the upper plateau changes. The modifications to the upper plateau are very interesting in the sense that it appears broken: its start stress gets lowered creating a new plateau up to the highest level of cyclic strain, followed by resuming the original plateau until full transformation. Since quite often the geometry of a device at the point at which it is subjected to cyclic loading is very much dependent on the manufacturing, deployment, and preloading sequence, it is important that analyses be conducted with the original material behavior up to that point, and then with the cyclic behavior thereafter.

Brain-Immune Interactions as the Basis of Gulf War Illness: Gulf War Illness Consortium (GWIC)

DTIC Science & Technology

2014-10-01

neuroinflammation as an end result of initial glial activation and subsequent priming of glial responses that cause a chronic activation loop of...infection, or physical trauma—that mobilizes CNS defense systems via activation of glia, the brain’s primary immune response cells, and release of...oligodendrocytes Microglial Activation (cytokine signaling) Behavioral Effects (fatigue, pain, cognitive problems) Astrocyte Activation (cytokine signaling

Parent Perspectives on Communication, Behavioral, and Instructional Strategies for Children and Youth Who Are Deaf-Blind.

ERIC Educational Resources Information Center

National Technical Assistance Consortium for Children and Young Adults Who Are Deaf-Blind, Monmouth, OR.

From July 30-August 1, 1998, eighty parents and family members from across the country attended a national workshop held in St. Louis, Missouri sponsored by the National Technical Assistance Consortium for Children and Young Adults who are Deaf-Blind and the National Family Association for Deaf-Blind. The workshop, entitled "Going for the Best:…

Standardized End Point Definitions for Coronary Intervention Trials: The Academic Research Consortium-2 Consensus Document.

PubMed

Garcia-Garcia, Hector M; McFadden, Eugène P; Farb, Andrew; Mehran, Roxana; Stone, Gregg W; Spertus, John; Onuma, Yoshinobu; Morel, Marie-Angèle; van Es, Gerrit-Anne; Zuckerman, Bram; Fearon, William F; Taggart, David; Kappetein, Arie-Pieter; Krucoff, Mitchell W; Vranckx, Pascal; Windecker, Stephan; Cutlip, Donald; Serruys, Patrick W

2018-06-12

The Academic Research Consortium (ARC)-2 initiative revisited the clinical and angiographic end point definitions in coronary device trials, proposed in 2007, to make them more suitable for use in clinical trials that include increasingly complex lesion and patient populations and incorporate novel devices such as bioresorbable vascular scaffolds. In addition, recommendations for the incorporation of patient-related outcomes in clinical trials are proposed. Academic Research Consortium-2 is a collaborative effort between academic research organizations in the United States and Europe, device manufacturers, and European, US, and Asian regulatory bodies. Several in-person meetings were held to discuss the changes that have occurred in the device landscape and in clinical trials and regulatory pathways in the last decade. The consensus-based end point definitions in this document are endorsed by the stakeholders of this document and strongly advocated for clinical trial purposes. This Academic Research Consortium-2 document provides further standardization of end point definitions for coronary device trials, incorporating advances in technology and knowledge. Their use will aid interpretation of trial outcomes and comparison among studies, thus facilitating the evaluation of the safety and effectiveness of these devices. © 2018 American Heart Association, Inc., and European Society of Cardiology.

The pediatric diabetes consortium: improving care of children with type 1 diabetes through collaborative research.

PubMed

2010-09-01

Although there are some interactions between the major pediatric diabetes programs in the United States, there has been no formal, independent structure for collaboration, the sharing of information, and the development of joint research projects that utilize common outcome measures. To fill this unmet clinical and research need, a consortium of seven pediatric diabetes centers in the United States has formed the Pediatric Diabetes Consortium (PDC) through an unrestricted grant from Novo Nordisk, Inc. (Princeton, NJ). This article describes the organizational structure of the PDC and the design of a study of important clinical outcomes in children and adolescents with new-onset, type 1 diabetes mellitus (T1DM). The outcomes study will describe the changes in A1c levels, the frequency of adverse events (diabetic ketoacidosis/severe hypoglycemia), and the frequency and timing of the "honeymoon" phase in newly diagnosed patients with T1DM over the first 12-24 months of the disease and examine the relationship between these clinical outcomes and demographic, socioeconomic, and treatment factors. This project will also allow the Consortium to develop a cohort of youth with T1DM whose clinical course has been well characterized and who wish to participate in future clinical trials and/or contribute to a repository of biological samples.

Collaborating at a Regional Scale for Climate Literacy and Action

NASA Astrophysics Data System (ADS)

Carlton, C.; Shcherba, O.

2016-12-01

Since 2014, the Bay Area Climate Literacy Impact Collaborative (Bay-CLIC) has been the leading regional consortium dedicated to improving climate education and action. Collectively, Bay-CLIC members reach over 3 million individuals through their educational programming, serve counties all throughout the Bay Area, offer multiple methods of climate communication like place-based school programs and visitor centers, and serve audiences representing all age groups. With over 30 organizations ranging from park agencies to science museums and nonprofits promoting energy efficiency, Bay-CLIC is preparing to push out climate change messaging through a suite of projects. Currently, Bay-CLIC's work is centered on building connections between educators and local scientists and region-specific climate data, implementing joint campaigns to promote the social norming of sustainable behavior change, and developing a toolkit and trainings targeted to the needs of Bay Area environmental educators. Meeting the needs of this diverse group offers many opportunities for increasing impact, growing new, strategic partnerships, as well as overcoming a few challenges along the way. Come learn more about what we've accomplished so far and what new, exciting projects are coming down the pike.

25 CFR 1000.73 - Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information from a non-BIA bureau? 1000.73 Section 1000.73 Indians OFFICE OF THE... § 1000.73 Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information...

Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study.

PubMed

Rebuli, Meghan E; Camacho, Luísa; Adonay, Maria E; Reif, David M; Aylor, David L; Patisaul, Heather B

2015-12-01

Bisphenol A (BPA) is a high volume production chemical and has been identified as an endocrine disruptor, prompting concern that developmental exposure could impact brain development and behavior. Rodent and human studies suggest that early life BPA exposure may result in an anxious, hyperactive phenotype but results are conflicting and data from studies using multiple doses below the no-observed-adverse-effect level are limited. To address this, the present studies were conducted as part of the CLARITY-BPA (Consortium Linking Academic and Regulatory Insights on BPA Toxicity) program. The impact of perinatal BPA exposure (2.5, 25, or 2500 µg/kg body weight (bw)/day) on behaviors related to anxiety and exploratory activity was assessed in juvenile (prepubertal) and adult NCTR Sprague-Dawley rats of both sexes. Ethinyl estradiol (0.5 µg/kg bw/day) was used as a reference estrogen. Exposure spanned gestation and lactation with dams gavaged from gestational day 6 until birth and then the offspring gavaged directly through weaning (n = 12/sex/group). Behavioral assessments included open field, elevated plus maze, and zero maze. Anticipated sex differences in behavior were statistically identified or suggested in most cases. No consistent effects of BPA were observed for any endpoint, in either sex, at either age compared to vehicle controls; however, significant differences between BPA-exposed and ethinyl estradiol-exposed groups were identified for some endpoints. Limitations of this study are discussed and include suboptimal statistical power and low concordance across behavioral tasks. These data do not indicate BPA-related effects on anxiety or exploratory activity in these developmentally exposed rats. © The Author 2015. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans

PubMed Central

Dao, David T.; Mahon, Pamela Belmonte; Cai, Xiang; Kovacsics, Colleen E.; Blackwell, Robert A.; Arad, Michal; Shi, Jianxin; Zandi, Peter P.; O’Donnell, Patricio; Knowles, James A.; Weissman, Myrna M.; Coryell, William; Scheftner, William A.; Lawson, William B.; Levinson, Douglas F.; Thompson, Scott M.; Potash, James B.; Gould, Todd D.

2010-01-01

Background Recent genome-wide association studies have associated polymorphisms in the gene CACNA1C, which codes for Cav1.2, with a bipolar disorder and depression diagnosis. Methods The behaviors of wild type and Cacna1c heterozygous mice of both sexes were evaluated in a number of tests. Based upon sex differences in our mouse data, we assessed a gene x sex interaction for diagnosis of mood disorders in human subjects. Data from the NIMH-BP Consortium and the GenRED Consortium were examined utilizing a combined dataset that included 2,021 mood disorder cases (1,223 females) and 1,840 controls (837 females). Results In both male and female mice, Cacna1c haploinsufficiency is associated with lower exploratory behavior, decreased response to amphetamine, and antidepressant-like behavior in the forced swim and tail suspension tests. Female, but not male, heterozygous mice displayed decreased risk-taking behavior or increased anxiety in multiple tests, greater attenuation of amphetamine-induced hyperlocomotion, decreased development of learned helplessness, and a decreased acoustic startle response indicating a sex-specific role of Cacna1c. In humans, sex-specific genetic association was seen for two intronic single nucleotide polymorphisms (SNPs), rs2370419 and rs2470411, in CACNA1C, with effects in females (OR=1.64, 1.32), but not in males (OR=0.82, 0.86). The interactions by sex were significant after correction for testing 190 SNPs (P=1.4 x 10−4, 2.1 x 10−4; Pcorrected=0.03, 0.04), and were consistent across two large data sets. Conclusions Our preclinical results support a role for CACNA1C in mood disorder pathophysiology, and the combination of human genetic and preclinical data support an interaction between sex and genotype. PMID:20723887

Developing a model for effects of climate change on human health and health-environment interactions: Heat stress in Austin, Texas

EPA Science Inventory

Background/Question/Methods In December, 2010, a consortium of EPA, Centers for Disease Control, and state and local health officials convened in Austin, Texas for a “participatory modeling workshop” on climate change effects on human health and health-environment interactions. ...

SOCIAL SCIENCE EDUCATION CONSORTIUM. PUBLICATION 106, ANTHROPOLOGY.

ERIC Educational Resources Information Center

BOHANNAN, PAUL

A CURRICULUM GUIDE OUTLINES THE MAJOR CONCEPTS, STRUCTURE, AND METHODS OF ANTHROPOLOGY FOR GRADES K-6. THE FOLLOWING UNIT AREAS ARE INCLUDED--(1) NEEDS AND NEED SATISFACTION, (2) HUMAN PERSONALITY, (3) SOCIAL GROUPS, (4) SOCIAL NETWORKS, (5) HUMAN CULTURE, (6) CHANGE AND EVOLUTION, AND (7) CURRENT CULTURAL CHANGES. A SUMMARY CHART PRESENTS A FLOW…

Achieving Sustainability through Targeted Curriculum Change. Strategies for Transformative Change

ERIC Educational Resources Information Center

Audant, B.; Kirby, C.

2016-01-01

Integrated academic skills instruction was one of the core elements of the CareerPATH consortium that provided math, reading, writing, and English language skills instruction "contextualized" to occupational training. Its goal was to engage adult learners and accelerate their progress in college and careers. The focus of this brief is…

Developing a model for effects of climate change on human health and health-environment interactions: Heat stress in Austin, Texas presentation

EPA Science Inventory

Background/Question/Methods In December, 2010, a consortium of EPA, Centers for Disease Control, and state and local health officials convened in Austin, Texas for a “participatory modeling workshop” on climate change effects on human health and health-environment int...

Relative quantitative PCR to assess bacterial community dynamics during biodegradation of diesel and biodiesel fuels under various aeration conditions.

PubMed

Cyplik, Paweł; Schmidt, Marcin; Szulc, Alicja; Marecik, Roman; Lisiecki, Piotr; Heipieper, Hermann J; Owsianiak, Mikołaj; Vainshtein, Mikhail; Chrzanowski, Łukasz

2011-03-01

The degradation of diesel fuel, B20 blend and biodiesel in liquid cultures by a seven-member bacterial consortium was compared under conditions with full aeration or with limited aeration with nitrate added as main electron acceptor. Community dynamics was assessed employing real-time PCR and the ddCt method for relative quantification. Biodegradation rates increased with increasing biodiesel content, but were significantly reduced under conditions with nitrate. Despite large variations in biodegradation rates, magnitude changes in population numbers were typically observed only from zero to one order, regardless the type of fuel and electron acceptor. Only Comamonadaceae and Variovorax sp. distinctly preferred aerobic conditions, and during aerobic growth showed suppression as fuel contained more biodiesel. Thus, the consortium is relatively stable and most of the degraders can shift their metabolism from hydrocarbons to biodiesel. The stability of the consortium is of interest in the context of biodiesel-mediated biodegradation of petroleum hydrocarbons. Copyright © 2010 Elsevier Ltd. All rights reserved.

Method for in situ biological conversion of coal to methane

DOEpatents

Volkwein, Jon C.

1995-01-01

A method and apparatus are provided for the in situ biological conversion of coal to methane comprising culturing on a coal-containing substrate a consortium of microorganisms capable of degrading the coal into methane under suitable conditions. This consortium of microorganisms can be obtained from an underground cavity such as an abandoned mine which underwent a change from being supplied with sewage to where no sewage was present, since these conditions have favored the development of microorganisms capable of using coal as a carbon source and converting coal to methane. The consortium of microorganisms obtained from such abandoned coal mines can be isolated and introduced to hard-to-reach coal-containing substrates which lack such microorganisms and which would otherwise remain unrecoverable. The present invention comprises a significant advantage in that useable energy can be obtained from a number of abandoned mine sites or other areas wherein coal is no longer being recovered, and such energy can be obtained in a safe, efficient, and inexpensive manner.

Consolidated Bio-Processing of Cellulosic Biomass for Efficient Biofuel Production Using Yeast Consortium

NASA Astrophysics Data System (ADS)

Goyal, Garima

Fossil fuels have been the major source for liquid transportation fuels for ages. However, decline in oil reserves and environmental concerns have raised a lot of interest in alternative and renewable energy sources. One promising alternative is the conversion of plant biomass into ethanol. The primary biomass feed stocks currently being used for the ethanol industry have been food based biomass (corn and sugar cane). However, interest has recently shifted to replace these traditional feed-stocks with more abundant, non-food based cellulosic biomass such as agriculture wastes (corn stover) or crops (switch grass). The use of cellulosic biomass as feed stock for the production of ethanol via bio-chemical routes presents many technical challenges not faced with the use of corn or sugar-cane as feed-stock. Recently, a new process called consolidated Bio-processing (CBP) has been proposed. This process combines simultaneous saccharification of lignocellulose with fermentation of the resulting sugars into a single process step mediated by a single microorganism or microbial consortium. Although there is no natural microorganism that possesses all properties of lignocellulose utilization and ethanol production desired for CBP, some bacteria and fungi exhibit some of the essential traits. The yeast Saccharomyces cerevisiae is the most attractive host organism for the usage of this strategy due to its high ethanol productivity at close to theoretical yields (0.51g ethanol/g glucose consumed), high osmo- and ethanol- tolerance, natural robustness in industrial processes, and ease of genetic manipulation. Introduction of the cellulosome, found naturally in microorganisms, has shown new directions to deal with recalcitrant biomass. In this case enzymes work in synergy in order to hydrolyze biomass more effectively than in case of free enzymes. A microbial consortium has been successfully developed, which ensures the functional assembly of minicellulosome on the yeast surface composed of four yeast populations. These yeast populations include: one displaying scaffoldin on its surface and three populations secreting three different cellulases in the medium to hydrolyze the cellulose. The modular nature of the consortium system allows for the fine-tuning of each population by changing their initial inoculum ratio, thereby optimizing the cellulose hydrolysis and hence ethanol production. When comparing the optimized consortium with equal ratio consortium, the optimized one produced almost double the amount of ethanol (1.87 g/l) with a yield of 0.475 g ethanol/g cellulose. To further evaluate the feasibility of using consortium for CBP, it was grown at very low optical density (OD) under anaerobic conditions. Under stressful conditions like low OD and no oxygen, the consortium system was proficient in assembling the cellulosome on its surface and growing on the PAS-avicel as sole carbon source and concomitantly producing ethanol with a yield of 87% of the theoretical value. For the dynamic study of yeast consortium system, quantitative real time PCR was used to enumerate the individual yeast population in the mixed culture. At the end of the cultivation, ratios of each population in this consortium maintained similar number as the initial inoculums ratios, which further confirms the consortium system is suitable for the application of CBP.

CPTAC Establishes Formal Relationships with Two Academic Institutions in Taiwan | Office of Cancer Clinical Proteomics Research

Cancer.gov

The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC) has entered into memorandum of understandings (MOUs) with Chang Gung University and Academia Sinica, in Taipei, Taiwan.

Evaluation of NASA space grant consortia programs

NASA Technical Reports Server (NTRS)

Eisenberg, Martin A.

1990-01-01

The meaningful evaluation of the NASA Space Grant Consortium and Fellowship Programs must overcome unusual difficulties: (1) the program, in its infancy, is undergoing dynamic change; (2) the several state consortia and universities have widely divergent parochial goals that defy a uniform evaluative process; and (3) the pilot-sized consortium programs require that the evaluative process be economical in human costs less the process of evaluation comprise the effectiveness of the programs they are meant to assess. This paper represents an attempt to assess the context in which evaluation is to be conducted, the goals and limitations inherent to the evaluation, and to recommend appropriate guidelines for evaluation.

Completion of the 2011 National Land Cover Database for the conterminous United States – Representing a decade of land cover change information

USGS Publications Warehouse

Homer, Collin G.; Dewitz, Jon; Yang, Limin; Jin, Suming; Danielson, Patrick; Xian, George Z.; Coulston, John; Herold, Nathaniel; Wickham, James; Megown, Kevin

2015-01-01

The National Land Cover Database (NLCD) provides nationwide data on land cover and land cover change at the native 30-m spatial resolution of the Landsat Thematic Mapper (TM). The database is designed to provide five-year cyclical updating of United States land cover and associated changes. The recent release of NLCD 2011 products now represents a decade of consistently produced land cover and impervious surface for the Nation across three periods: 2001, 2006, and 2011 (Homer et al., 2007; Fry et al., 2011). Tree canopy cover has also been produced for 2011 (Coluston et al., 2012; Coluston et al., 2013). With the release of NLCD 2011, the database provides the ability to move beyond simple change detection to monitoring and trend assessments. NLCD 2011 represents the latest evolution of NLCD products, continuing its focus on consistency, production, efficiency, and product accuracy. NLCD products are designed for widespread application in biology, climate, education, land management, hydrology, environmental planning, risk and disease analysis, telecommunications and visualization, and are available for no cost at http://www.mrlc.gov. NLCD is produced by a Federal agency consortium called the Multi-Resolution Land Characteristics Consortium (MRLC) (Wickham et al., 2014). In the consortium arrangement, the U.S. Geological Survey (USGS) leads NLCD land cover and imperviousness production for the bulk of the Nation; the National Oceanic and Atmospheric Administration (NOAA) completes NLCD land cover for the conterminous U.S. (CONUS) coastal zones; and the U.S. Forest Service (USFS) designs and produces the NLCD tree canopy cover product. Other MRLC partners collaborate through resource or data contribution to ensure NLCD products meet their respective program needs (Wickham et al., 2014).

The Johns Hopkins RTR Consortium: A Collaborative Approach to Advance Translational Science and Standardize Clinical Monitoring of Restorative Transplantation

DTIC Science & Technology

2016-10-01

based Therapy, Large animal models, Allograft, Hand Transplantation ,Face Transplantation 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT...Changes in Approach b. Problems/Delays and Plans for Resolution c. Changes that Impacted Expenditures d. Changes in use or care of vertebrate animals ...Vascularized Composite Allotransplantation Immunoregulation Tolerance Rejection Ischemia Reperfusion Cell based Therapy Large animal models

Proposed regulations for research with biospecimens: responses from stakeholders at CTSA consortium institutions.

PubMed

Botkin, Jeffrey R; Anderson, Rebecca; Murray, Tom; Beskow, Laura M; Maschke, Karen; Cuttler, Leona

2014-04-01

Secondary research with biospecimens acquired through clinical care and through research is often conducted without the informed consent of individuals from whom the specimens were acquired. While such uses are consistent with the current federal regulations, surveys of the general public suggest that many individuals would prefer more information and choice regarding research use of biospecimens. The federal government issued an Advance Notice of Proposed Rulemaking (ANPRM) in 2011 that proposed a number of potential changes in the regulations governing human subjects. These proposed regulations are particularly pertinent to institutions committed to research involving human subjects-including institutions in the NIH-funded Clinical and Translational Science Awards (CTSA) consortium. In this study, we reviewed public responses by CTSA-funded institutions and CTSA-affiliated organizations and groups regarding the proposed changes in the ANPRM with respect to research with biospecimens. Our results indicate that the majority of responses to the ANPRM from CTSA institutions were not supportive of the proposed changes. While many responses acknowledge a need to change current research practices regarding biospecimens, the proposed changes in the ANPRM received only limited support from this subgroup of academic research institutions. © 2014 Wiley Periodicals, Inc.

Proposed Regulations for Research with Biospecimens: Responses from Stakeholders at CTSA Consortium Institutions

PubMed Central

Botkin, Jeffrey R; Anderson, Rebecca; Murray, Tom; Beskow, Laura M.; Maschke, Karen; Cuttler, Leona

2014-01-01

Secondary research with biospecimens acquired through clinical care and through research is often conducted without the informed consent of individuals from whom the specimens were acquired. While such uses are consistent with the current federal regulations, surveys of the general public suggest that many individuals would prefer more information and choice regarding research use of biospecimens. The federal government issued an Advance Notice of Proposed Rulemaking (ANPRM) in 2011 that proposed a number of potential changes in the regulations governing human subjects. These proposed regulations are particularly pertinent to institutions committed to research involving human subjects – including institutions in the NIH-funded Clinical and Translational Science Awards (CTSA) consortium. In this study, we reviewed public responses by CTSA-funded institutions and CTS-affiliated organizations and groups regarding the proposed changes in the ANPRM with respect to research with biospecimens. Our results indicate that the majority of responses to the ANPRM from CTSA institutions were not supportive of the proposed changes. While many responses acknowledge a need to change current research practices regarding biospecimens, the proposed changes in the ANPRM received only limited support from this subgroup of academic research institutions. PMID:24459038

Experimental data of lithium-ion battery and ultracapacitor under DST and UDDS profiles at room temperature.

PubMed

Wang, Yujie; Liu, Chang; Pan, Rui; Chen, Zonghai

2017-06-01

This article provides the dataset of both the LiFePO 4 type lithium-ion battery (LIB) behavior and the Maxwell ultracapacitor behavior. The dynamic stress test (DST) condition and the urban dynamometer driving schedule (UDDS) condition were carried out to analyze the battery/ultracapacitor features. The datasets were achieved at room temperature, in August, 2016. The shared data contributes to clarify the behavior of the LIBs and ultracapacitors and can be used to predict the state-of-charge (SOC) of the LIBs and ultracapacitors, which is also shown in the article of "Modeling and state-of-charge prediction of lithium-ion battery and ultracapacitor hybrids with a co-estimator" (United States Advanced Battery Consortium, 1996) [1].

Military and Veterans Rehabilitation and Recovery from Injury Network (MAVERICK): Chronic Effects of Neurotrauma Consortium (CENC)

DTIC Science & Technology

2015-10-01

novel interventions to prevent or mitigate cognitive and behavioral decline, and contribute to long-term planning for service member and veterans...Neurodegeneration, and CENC 0056 Visual Sensory Impairments. j. “Vestibular Sensory Deficits and Cognitive Adaptation in mTBI” study was approved by... Goldstein perform electron micrographic analysis at Boston University. V. Biostatistics [B], Data Management [DM], and Study Management [SM] Core

Changing the Face of Educational Leadership: A Unique Method of Mentoring Hispanic Doctoral Students.

ERIC Educational Resources Information Center

Menchaca, Velma D.; Estrada, Veronica Lopez; Cavazos, Christina; Ramirez, Diana

The Hispanic Border Leadership Institute (HBLI) is a consortium of six Southwestern universities that promotes the improvement of education for Hispanics at all levels, K-16, particularly on the U.S.-Mexico border. HBLI seeks to bring about systematic change in education by designing new approaches to the doctoral preparation programs of…

Zero-sum politics, the Herbert thesis, and the Ryan White CARE Act: lessons learned from the local side of AIDS.

PubMed

Slack, J

2001-01-01

This study examines the dynamics of grass-roots decision-making processes involved in the implementation of the Ryan White CARE Act. Providing social services to persons with HIV/AIDS, the CARE act requires participation of all relevant groups, including representatives of the HIV/AIDS and gay communities. Decision-making behavior is explored by applying a political (zero-sum) model and a bureaucratic (the Herbert Thesis) model. Using qualitative research techniques, the Kern County (California) Consortium is used as a case study. Findings shed light on the decision-making behavior of social service organizations characterized by intense advocacy and structured on the basis of volunteerism and non-hierarchical relationships. Findings affirm bureaucratic behavior predicted by the Herbert Thesis and also discern factors which seem to trigger more conflictual zero-sum behavior.

Keck Geology Consortium Lava Project: Undergraduate Research Linking Natural and Experimental Basaltic Lava Flows

NASA Astrophysics Data System (ADS)

Karson, J. A.; Hazlett, R. W.; Wysocki, R.; Bromfield, M. E.; Browne, N. C.; Davis, N. C.; Pelland, C. G.; Rowan, W. L.; Warner, K. A.

2014-12-01

Undergraduate students in the Keck Geology Consortium Lava Project participated in a month-long investigation of features of basaltic lava flows from two very different perspectives. The first half of the project focused on field relations in basaltic lava flows from the 1984 Krafla Fires eruption in northern Iceland. Students gained valuable experience in the collection of observations and samples in the field leading to hypotheses for the formation of selected features related to lava flow dynamics. Studies focused on a wide range of features including: morphology and heat loss in lava tubes (pyroducts), growth and collapse of lava ponds and overflow deposits, textural changes of lava falls (flow over steep steps), spaced spatter cones from flows over wet ground, and anisotropy of magnetic susceptibility related to flow kinematics. In the second half of the program students designed, helped execute, documented, and analyzed features similar to those they studied in the field with large-scale (50-250 kg) basaltic lava flows created in the Syracuse University Lava Project (http://lavaproject.syr.edu). Data collected included video from multiple perspectives, infrared thermal (FLIR) images, still images, detailed measurements of flow dimensions and rates, and samples for textural and magnetic analyses. Experimental lava flow features provided critical tests of hypotheses generated in the field and a refined understanding of the behavior and final morphology of basaltic lava flows. The linked field and experimental studies formed the basis for year-long independent research projects under the supervision of their faculty mentors, leading to senior theses at the students' respective institutions.

The political anatomy of a guideline: a collaborative effort to develop the AHCPR-sponsored practice guideline on otitis media with effusion.

PubMed

Sebring, R H; Herrerias, C T

1996-06-01

In July 1991 the Agency for Health Care Policy and Research (AHCPR) invited private organizations to develop a practice guideline on otitis media. The American Academy of Pediatrics (AAP) collaborated with the American Academy of Family Physicians, the American Academy of Otolaryngology-Head and Neck Surgery, and the Department of Pediatric Otolaryngology at the University of Pittsburgh in preparing a proposal. The AAP--the prime contractor--and the consortium were awarded the contract in October 1991. The 19-member panel assessed evidence and achieved consensus on most recommendations and maintained positive relationships that helped them function as a group. The practice guideline project has influenced the AAP's own evidence-based practice parameter methodology. Many lessons were learned. For example, since any project is only as strong as its weakest link, it was important to build the proposal on organizational strengths--including access to a combined 244,000 members and other resources. The weak links were the large number of persons involved in the project, their varying time commitments, and the wide geographic distribution of those involved. Also, neither AHCPR nor any of the organizations involved in the consortium had previous government contract experience in developing practice guidelines, so that much of the process became "on-the-job training". Research is needed to determine the extent to which the otitis media guideline is being used. The three academies are conducting a follow-up practice pattern variation study of pediatricians, family physicians, and otolaryngologists, which may provide data on behavior change with regard to managing the condition.

Case study of how successful coordination was achieved between a mental health and social care service in Sweden.

PubMed

Hansson, Johan; Øvretveit, John; Brommels, Mats

2012-01-01

This paper summarises the findings from an empirical longitudinal study of a health and social care consortium for people with mental health problems in one area in Stockholm. The aim was to describe the formation and structure of coordination within the consortium, and to assess the intermediate impact on care processes and client outcomes. A multiple-method case study design, theoretically informed by the Pettigrew and Whipp model of strategic change (1993) was applied. Data was gathered from interviews with informants from different organisations at different times in the development of the consortium, and from administrative documents, plans and service statistics showing some of the intermediate changes and client outcomes. The findings revealed activities and factors both helping and hindering the formation of coordination arrangements. One of the most significant hindering factors was the central county purchasing organisation focusing more on volume and costs, with payments for specific units and services, and with less emphasis on quality of the services. Few studies have described implementation of changes to improve coordination with reference to context over a long period of time, as well as assessing different results. This study contributes to knowledge about improved methods for this type of research, as well as knowledge about developing coordination between public health and welfare services. One lesson for the current policy is that, where full structural integration is not possible, then client-level coordination roles in each sector are useful to connect sector services for shared clients. Copyright © 2011 John Wiley & Sons, Ltd.

Biodegradation of benzo[α]pyrene, toluene, and formaldehyde from the gas phase by a consortium of Rhodococcus erythropolis and Fusarium solani.

PubMed

Morales, Paulina; Cáceres, Manuel; Scott, Felipe; Díaz-Robles, Luis; Aroca, Germán; Vergara-Fernández, Alberto

2017-09-01

Polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs) are important indoor contaminants. Their hydrophobic nature hinders the possibility of biological abatement using biofiltration. Our aim was to establish whether the use of a consortium of Fusarium solani and Rhodococcus erythropolis shows an improved performance (in terms of mineralization rate and extent) towards the degradation of formaldehyde, as a slightly polar VOC; toluene, as hydrophobic VOC; and benzo[α]pyrene (BaP) as PAH at low concentrations compared to a single-species biofilm in serum bottles with vermiculite as solid support to mimic a biofilter and to relate the possible improvements with the surface hydrophobicity and partition coefficient of the biomass at three different temperatures. Results showed that the hydrophobicity of the surface of the biofilms was affected by the hydrophobicity of the carbon source in F. solani but it did not change in R. erythropolis. Similarly, the partition coefficients of toluene and BaP in F. solani biomass (both as pure culture and consortium) show a reduction of up to 38 times compared to its value in water, whereas this reduction was only 1.5 times in presence of R. erythropolis. Despite that increments in the accumulated CO 2 and its production rate were found when F. solani or the consortium was used, the mineralization extent of toluene was below 25%. Regarding BaP degradation, the higher CO 2 production rates and percent yields were obtained when a consortium of F. solani and R. erythropolis was used, despite a pure culture of R. erythropolis exhibits poor mineralization of BaP.

The Multi-Resolution Land Characteristics (MRLC) Consortium: 20 years of development and integration of USA national land cover data

USGS Publications Warehouse

Wickham, James D.; Homer, Collin G.; Vogelmann, James E.; McKerrow, Alexa; Mueller, Rick; Herold, Nate; Coluston, John

2014-01-01

The Multi-Resolution Land Characteristics (MRLC) Consortium demonstrates the national benefits of USA Federal collaboration. Starting in the mid-1990s as a small group with the straightforward goal of compiling a comprehensive national Landsat dataset that could be used to meet agencies’ needs, MRLC has grown into a group of 10 USA Federal Agencies that coordinate the production of five different products, including the National Land Cover Database (NLCD), the Coastal Change Analysis Program (C-CAP), the Cropland Data Layer (CDL), the Gap Analysis Program (GAP), and the Landscape Fire and Resource Management Planning Tools (LANDFIRE). As a set, the products include almost every aspect of land cover from impervious surface to detailed crop and vegetation types to fire fuel classes. Some products can be used for land cover change assessments because they cover multiple time periods. The MRLC Consortium has become a collaborative forum, where members share research, methodological approaches, and data to produce products using established protocols, and we believe it is a model for the production of integrated land cover products at national to continental scales. We provide a brief overview of each of the main products produced by MRLC and examples of how each product has been used. We follow that with a discussion of the impact of the MRLC program and a brief overview of future plans.

The Future of Postgraduate Medical Education in Canada.

PubMed

Busing, Nick; Harris, Ken; MacLellan, Anne-Marie; Moineau, Geneviève; Oandasan, Ivy; Rourke, James; Saxena, Anurag

2015-09-01

The Future of Medical Education in Canada Postgraduate (FMEC PG) Project was launched in 2010 by a consortium of four organizations: the Association of Faculties of Medicine of Canada, the Collège des Médecins du Québec, the College of Family Physicians of Canada, and the Royal College of Physicians and Surgeons of Canada. The FMEC PG study set out to review the state of the Canadian postgraduate medical education (PGME) system and make recommendations for improvements and changes. The extensive process included literature reviews, commissioned papers, stakeholder interviews, international consultations, and dialogue with the public and learners. The resulting key findings and 10 recommendations, published in a report in 2012, represent the collective vision of the consortium partner organizations for PGME in Canada. Implementation of the recommendations began in 2013 and will continue beyond 2016.In this article, the authors describe the complex process of developing the recommendations, highlight several recommendations, consider implementation processes and issues, and share lessons learned to date. They reflect on the ways in which the transformation of a very complex and complicated PGME system has required many stakeholders to work together on multiple interventions simultaneously. Notwithstanding the challenges for the participating organizations, changes have been introduced and sustainability is being forged. Throughout this process, the consortium partners and other stakeholders have continued to address the social accountability role of all physicians with respect to the public they serve.

Evaluating efforts to diversify the biomedical workforce: the role and function of the Coordination and Evaluation Center of the Diversity Program Consortium.

PubMed

McCreath, Heather E; Norris, Keith C; Calderόn, Nancy E; Purnell, Dawn L; Maccalla, Nicole M G; Seeman, Teresa E

2017-01-01

The National Institutes of Health (NIH)-funded Diversity Program Consortium (DPC) includes a Coordination and Evaluation Center (CEC) to conduct a longitudinal evaluation of the two signature, national NIH initiatives - the Building Infrastructure Leading to Diversity (BUILD) and the National Research Mentoring Network (NRMN) programs - designed to promote diversity in the NIH-funded biomedical, behavioral, clinical, and social sciences research workforce. Evaluation is central to understanding the impact of the consortium activities. This article reviews the role and function of the CEC and the collaborative processes and achievements critical to establishing empirical evidence regarding the efficacy of federally-funded, quasi-experimental interventions across multiple sites. The integrated DPC evaluation is particularly significant because it is a collaboratively developed Consortium Wide Evaluation Plan and the first hypothesis-driven, large-scale systemic national longitudinal evaluation of training programs in the history of NIH/National Institute of General Medical Sciences. To guide the longitudinal evaluation, the CEC-led literature review defined key indicators at critical training and career transition points - or Hallmarks of Success. The multidimensional, comprehensive evaluation of the impact of the DPC framed by these Hallmarks is described. This evaluation uses both established and newly developed common measures across sites, and rigorous quasi-experimental designs within novel multi-methods (qualitative and quantitative). The CEC also promotes shared learning among Consortium partners through working groups and provides technical assistance to support high-quality process and outcome evaluation internally of each program. Finally, the CEC is responsible for developing high-impact dissemination channels for best practices to inform peer institutions, NIH, and other key national and international stakeholders. A strong longitudinal evaluation across programs allows the summative assessment of outcomes, an understanding of factors common to interventions that do and do not lead to success, and elucidates the processes developed for data collection and management. This will provide a framework for the assessment of other training programs and have national implications in transforming biomedical research training.

Optimization of a Centrifugal Impeller Design Through CFD Analysis

NASA Technical Reports Server (NTRS)

Chen, W. C.; Eastland, A. H.; Chan, D. C.; Garcia, Roberto

1993-01-01

This paper discusses the procedure, approach and Rocketdyne CFD results for the optimization of the NASA consortium impeller design. Two different approaches have been investigated. The first one is to use a tandem blade arrangement, the main impeller blade is split into two separate rows with the second blade row offset circumferentially with respect to the first row. The second approach is to control the high losses related to secondary flows within the impeller passage. Many key parameters have been identified and each consortium team member involved will optimize a specific parameter using 3-D CFD analysis. Rocketdyne has provided a series of CFD grids for the consortium team members. SECA will complete the tandem blade study, SRA will study the effect of the splitter blade solidity change, NASA LeRC will evaluate the effect of circumferential position of the splitter blade, VPI will work on the hub to shroud blade loading distribution, NASA Ames will examine the impeller discharge leakage flow impacts and Rocketdyne will continue to work on the meridional contour and the blade leading to trailing edge work distribution. This paper will also present Rocketdyne results from the tandem blade study and from the blade loading distribution study. It is the ultimate goal of this consortium team to integrate the available CFD analysis to design an advanced technology impeller that is suitable for use in the NASA Space Transportation Main Engine (STME) fuel turbopump.

Oceanic Communities in a Changing Planet - The Tara Oceans Project (GSC8 Meeting)

ScienceCinema

Raes, Jeroen

2018-01-10

The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding Research Coordination Network from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. Jeroen Raes of the University of Brussels discusses the Tara-Oceans expedition at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, CA on Sept. 9, 2009.

PanScan, the Pancreatic Cancer Cohort Consortium, and the Pancreatic Cancer Case-Control Consortium

Cancer.gov

The Pancreatic Cancer Cohort Consortium consists of more than a dozen prospective epidemiologic cohort studies within the NCI Cohort Consortium, whose leaders work together to investigate the etiology and natural history of pancreatic cancer.

Biodegradation of 2,4,6-trichlorophenol in a packed-bed biofilm reactor equipped with an internal net draft tube riser for aeration and liquid circulation.

PubMed

Jesús, A Gómez-De; Romano-Baez, F J; Leyva-Amezcua, L; Juárez-Ramírez, C; Ruiz-Ordaz, N; Galíndez-Mayer, J

2009-01-30

For the aerobic biodegradation of the fungicide and defoliant 2,4,6-trichlorophenol (2,4,6-TCP), a bench-scale packed-bed bioreactor equipped with a net draft tube riser for liquid circulation and oxygenation (PB-ALR) was constructed. To obtain a high packed-bed volume relative to the whole bioreactor volume, a high A(D)/A(R) ratio was used. Reactor's downcomer was packed with a porous support of volcanic stone fragments. PB-ALR hydrodynamics and oxygen mass transfer behavior was evaluated and compared to the observed behavior of the unpacked reactor operating as an internal airlift reactor (ALR). Overall gas holdup values epsilon(G), and zonal oxygen mass transfer coefficients determined at various airflow rates in the PB-ALR, were higher than those obtained with the ALR. When comparing mixing time values obtained in both cases, a slight increment in mixing time was observed when reactor was operated as a PB-ALR. By using a mixed microbial community, the biofilm reactor was used to evaluate the aerobic biodegradation of 2,4,6-TCP. Three bacterial strains identified as Burkholderia sp., Burkholderia kururiensis and Stenotrophomonas sp. constituted the microbial consortium able to cometabolically degrade the 2,4,6-TCP, using phenol as primary substrate. This consortium removed 100% of phenol and near 99% of 2,4,6-TCP. Mineralization and dehalogenation of 2,4,6-TCP was evidenced by high COD removal efficiencies ( approximately 95%), and by the stoichiometric release of chloride ions from the halogenated compound ( approximately 80%). Finally, it was observed that the microbial consortium was also capable to metabolize 2,4,6-TCP without phenol as primary substrate, with high removal efficiencies (near 100% for 2,4,6-TCP, 92% for COD and 88% for chloride ions).

ENVISIONING ALTERNATIVES: USING CITIZEN GUIDANCE TO MAP FUTURE LAND AND WATER USE

EPA Science Inventory

Spatially explicit landscape analyses are a central activity in research on the relationships between people and changes in natural systems. Using geographical information systems and related tools, the Pacific Northwest Ecosystem Research Consortium depicted historical (pre-Eur...

Northern New Jersey Nursing Education Consortium: a partnership for graduate nursing education.

PubMed

Quinless, F W; Levin, R F

1998-01-01

The purpose of this article is to describe the evolution and implementation of the Northern New Jersey Nursing Education consortium--a consortium of seven member institutions established in 1992. Details regarding the specific functions of the consortium relative to cross-registration of students in graduate courses, financial disbursement of revenue, faculty development activities, student services, library privileges, and institutional research review board mechanisms are described. The authors also review the administrative organizational structure through which the work conducted by the consortium occurs. Both the advantages and disadvantages of such a graduate consortium are explored, and specific examples of recent potential and real conflicts are fully discussed. The authors detail governance and structure of the consortium as a potential model for replication in other environments.

Delivering Coordinated, Community-Based Services by Putting Networks into Action: New York City's Change Capital Fund. No. 3

ERIC Educational Resources Information Center

Aceves, Aurelia De La Rosa; Greenberg, David M.; Schell, Sarah

2016-01-01

This brief is the third in a series documenting the implementation of an economic mobility initiative supported by New York City's Change Capital Fund (CCF). CCF is a consortium of New York City donors formed to invest in local nonprofits that undertake data-driven antipoverty strategies integrating housing, education, and employment services. CCF…

How Has Vocational Culinary Arts Changed as a Result of a Redesign of the Education System.

ERIC Educational Resources Information Center

VanLandingham, Paul G.

Vocational education reforms that followed passage of the Carl D. Perkins Vocational Education Act of 1963 initiated the development of many new vocational culinary arts programs that trained high school students with state-of-the art equipment. When the National Consortium of Competency Based Education was established in 1973, it changed the form…

Mapping New Terrain: Climate Change and America's West. Report of the Consortium for Integrated Climate Research in Western Mountains (CIRMOUNT)

Treesearch

Henry F. CIRMOUNT Committee (Diaz; Constance I. Millar; Daniel R. Cayan; Michael D. Dettinger; Daniel B. Fagre; Lisa J. Graumlich; Greg Greenwood; Malcolm K. Hughes; David L. Peterson; Frank L. Powell; Kelly T. Redmond; Nathan L. Stephenson; Thomas W. Swetnam; Connie) Woodhouse

2006-01-01

Climate variability and sustained change presage far-reaching transformations across America’s West, an expanse dominated by immense mountain ranges and interspersed with important urban centers. These mountains provide the region’s life blood—water that courses through its streams and runs out its faucets, power that fuels its industries...

Metrics for Operator Situation Awareness, Workload, and Performance in Automated Separation Assurance Systems

NASA Technical Reports Server (NTRS)

Strybel, Thomas Z.; Vu, Kim-Phuong L.; Battiste, Vernol; Dao, Arik-Quang; Dwyer, John P.; Landry, Steven; Johnson, Walter; Ho, Nhut

2011-01-01

A research consortium of scientists and engineers from California State University Long Beach (CSULB), San Jose State University Foundation (SJSUF), California State University Northridge (CSUN), Purdue University, and The Boeing Company was assembled to evaluate the impact of changes in roles and responsibilities and new automated technologies, being introduced in the Next Generation Air Transportation System (NextGen), on operator situation awareness (SA) and workload. To meet these goals, consortium members performed systems analyses of NextGen concepts and airspace scenarios, and concurrently evaluated SA, workload, and performance measures to assess their appropriateness for evaluations of NextGen concepts and tools. The following activities and accomplishments were supported by the NRA: a distributed simulation, metric development, systems analysis, part-task simulations, and large-scale simulations. As a result of this NRA, we have gained a greater understanding of situation awareness and its measurement, and have shared our knowledge with the scientific community. This network provides a mechanism for consortium members, colleagues, and students to pursue research on other topics in air traffic management and aviation, thus enabling them to make greater contributions to the field

Bridging the Gap with the Pacific Climate Impacts Consortium (PCIC)

NASA Astrophysics Data System (ADS)

Rodenhuis, D.; Kangasniemi, B.; Murdock, T. Q.

2008-12-01

The difficulty of translating scientific results into useful information defines the abyss that is addressed by a new PCIC consortium of academics-government-industry at the University of Victoria. The scope of the consortium is research applications of climate variability and change, including extreme weather events, for climate impacts and adaptation in Pacific North America. During the past 3 years traditional tools of collaboration have been utilized--both with the science community and with stakeholders. Some success in networking with Provinces, the States, and with national institutions has been achieved. Limitations of governance/management, resources, and cooperation have been identified. Input and statements of need from the climate stakeholders in government and industry has been achieved, but only in specific areas - water/power generation, forestry, communities. Three examples will be given of successful engagement of stakeholders. These examples demonstrate how difficult it is to summarize effectiveness, relevance, and capacity. This experience, and early decisions on scope, focus and priorities have taken us this far, but some exceptional challenges have arisen due to the stakeholder demand for new (geophysical) design conditions for the 21st century.

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 603.515 Qualification of a consortium. (a) A consortium that... under the agreement. (b) If the prospective recipient of a TIA is a consortium that is not formally...

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 603.515 Qualification of a consortium. (a) A consortium that... under the agreement. (b) If the prospective recipient of a TIA is a consortium that is not formally...

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 603.515 Qualification of a consortium. (a) A consortium that... under the agreement. (b) If the prospective recipient of a TIA is a consortium that is not formally...

25 CFR 1000.33 - What amount of funding is to be removed from the Consortium's AFA for the withdrawing Tribe?

Code of Federal Regulations, 2010 CFR

2010-04-01

... Participation in Tribal Self-Governance Withdrawal from A Consortium Annual Funding Agreement § 1000.33 What... the Consortium agreement is reduced if: (1) The Consortium, Tribe, OSG, and bureau agree it is...

The Johns Hopkins RTR Consortium: A Collaborative Approach to Advance Translational Science and Standardize Clinical Monitoring of Restorative Transplantation

DTIC Science & Technology

2014-10-01

Changes in Approach b. Problems/Delays and Plans for Resolution c. Changes that Impacted Expenditures d. Changes in use or care of vertebrate animals...the field of Restorative Transplantation matures , significant opportunities are emerging for transplant researchers and clinicians to capitalize on...that the maturing field of Restorative Transplantation will benefit the most from the establishment of a multi-institutional, multi-disciplinary

Worldwide Consortium for the Grid (W2COG) Research Initiative Phase 1

DTIC Science & Technology

2006-03-31

weight 3 Observable features A changed set of observables 3 Aggregation A change in overall composition 4 Components A change in units aggregated ...Knowledge Unit • Health • Process • Prerequisite • Supply • Supplier 145 • Transport • Target • Center of Gravity • Line of Communication...number of successful and well documented netcentric pilots. The aggregate value of these pilots far exceeds the investment, and proves the hypothesis

Adolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and Behavior

PubMed Central

Vetreno, Ryan P.; Broadwater, Margaret A.; Robinson, Donita L.

2016-01-01

Adolescence is a developmental period when physical and cognitive abilities are optimized, when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal cortical functions mature to adult levels. Adolescents also have unique responses to alcohol compared with adults, being less sensitive to ethanol sedative–motor responses that most likely contribute to binge drinking and blackouts. Population studies find that an early age of drinking onset correlates with increased lifetime risks for the development of alcohol dependence, violence, and injuries. Brain synapses, myelination, and neural circuits mature in adolescence to adult levels in parallel with increased reflection on the consequence of actions and reduced impulsivity and thrill seeking. Alcohol binge drinking could alter human development, but variations in genetics, peer groups, family structure, early life experiences, and the emergence of psychopathology in humans confound studies. As adolescence is common to mammalian species, preclinical models of binge drinking provide insight into the direct impact of alcohol on adolescent development. This review relates human findings to basic science studies, particularly the preclinical studies of the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium. These studies focus on persistent adult changes in neurobiology and behavior following adolescent intermittent ethanol (AIE), a model of underage drinking. NADIA studies and others find that AIE results in the following: increases in adult alcohol drinking, disinhibition, and social anxiety; altered adult synapses, cognition, and sleep; reduced adult neurogenesis, cholinergic, and serotonergic neurons; and increased neuroimmune gene expression and epigenetic modifiers of gene expression. Many of these effects are specific to adolescents and not found in parallel adult studies. AIE can cause a persistence of adolescent-like synaptic physiology, behavior, and sensitivity to alcohol into adulthood. Together, these findings support the hypothesis that adolescent binge drinking leads to long-lasting changes in the adult brain that increase risks of adult psychopathology, particularly for alcohol dependence. PMID:27677720

Earth science information: Planning for the integration and use of global change information

NASA Technical Reports Server (NTRS)

Lousma, Jack R.

1992-01-01

The Consortium for International Earth Science Information Network (CIESIN) was founded in 1989 as a non-profit corporation dedicated to facilitating access to, use and understanding of global change information worldwide. The Consortium was created to cooperate and coordinate with organizations and researchers throughout the global change community to further access the most advanced technology, the latest scientific research, and the best information available for critical environmental decision making. CIESIN study efforts are guided by Congressional mandates to 'convene key present and potential users to assess the need for investment in integration of earth science information,' to 'outline the desirable pattern of interaction with the scientific and policy community,' and to 'develop recommendations and draft plans to achieve the appropriate level of effort in the use of earth science data for research and public policy purposes.' In addition, CIESIN is tasked by NASA to develop a data center that would extend the benefits of Earth Observing System (EOS) to the users of global change information related to human dimensions issues. For FY 1991, CIESIN focused on two main objectives. The first addressed the identification of information needs of global change research and non-research user groups worldwide. The second focused on an evaluation of the most efficient mechanisms for making this information available in usable forms.

25 CFR 1000.310 - What information must the Tribe's/Consortium's response contain?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false What information must the Tribe's/Consortium's response... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.310 What information must the Tribe's/Consortium's response contain? (a) The Tribe's/Consortium's response must indicate the specific measures that...

25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among construction...

25 CFR 1000.310 - What information must the Tribe's/Consortium's response contain?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false What information must the Tribe's/Consortium's response... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.310 What information must the Tribe's/Consortium's response contain? (a) The Tribe's/Consortium's response must indicate the specific measures that...

25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among construction...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development Regulations Relating to Housing and... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

Comparative Metabolomic Analysis of the Green Microalga Chlorella sorokiniana Cultivated in the Single Culture and a Consortium with Bacteria for Wastewater Remediation.

PubMed

Chen, Taojing; Zhao, Quanyu; Wang, Liang; Xu, Yunfeng; Wei, Wei

2017-11-01

Co-culture of microalgae with many types of bacteria usually comes out with significant different treatment efficiencies for COD, nitrogen, and phosphorus in wastewater remediation, compared with the single culture. In order to understand the mechanism behind, a comparative experiment was designed in this study, using the green microalgae species Chlorella sorokiniana in the single culture and a consortium with a bacterium, Pseudomonas H4, for nutrient removal. Comparative metabolome profile analysis was conducted to reveal the Chlorella cell responses to the synergistic growth with the bacteria, and possible relations between the metabolic regulation of microalgae and the nutrient degradation were discussed. The detectable differential metabolites of Chlorella belonged to several classes, including carbohydrates, fatty acids, amino acids, phosphates, polyols, etc. The orthogonal partial least squares discriminant analysis (OPLS-DA) model of the identified metabolites suggests the metabolism in this alga was significantly affected by the bacteria, corresponding to different treatment behaviors.

CERAD (Consortium to Establish a Registry for Alzheimer’s Disease) The first 20 years

PubMed Central

Fillenbaum, Gerda G.; van Belle, Gerald; Morris, John C.; Mohs, Richard C.; Mirra, Suzanne S.; Davis, Patricia C.; Tariot, Pierre N.; Silverman, Jeremy M.; Clark, Christopher M.; Welsh-Bohmer, Kathleen A.; Heyman, Albert

2009-01-01

The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) was funded by the National Institute on Aging in 1986 to develop standardized, validated measures for the assessment of Alzheimer’s disease (AD). The present report describes the measures that CERAD developed during its first decade, and their continued use in their original and translated forms. These measures include clinical, neuropsychological, neuropathological and behavioral assessments of AD, and also assessment of family history and parkinsonism in AD. An approach to evaluating neuroimages did not meet the standards desired. Further evaluations which could not be completed because of lack of funding (but where some materials are available), include evaluation of very severe AD, and of service use and need by patient and caregiver. The information that was developed in the U.S. and abroad permits standardized assessment of AD in clinical practice, facilitates epidemiological studies, and provides information valuable for individual and public health planning. CERAD materials and data remain available for those wishing to use them. PMID:18631955

Metabolism and biotransformation of azo dye by bacterial consortium studied in a bioreaction calorimeter.

PubMed

Shanmugam, Bhuvanesh Kumar; Mahadevan, Surianarayanan

2015-11-01

Effluents from leather and textile industries are difficult for treatment owing to its recalcitrant nature. Since the volume of effluent generated are high, a robust and active microbial consortia is required for effective treatment. The focus in the present study is the calorimetric traceability of the metabolic behaviors of mixed microbial consortia, while it grows and degrades recalcitrant substance such as an azo dye acid blue 113. The consortium exhibited a syntrophic division of substrate and was effective in degrading dye up to 0.8g/l. Notably, it was able to degrade 93.7% of the azo dye in 12-16h whereas its monocultures required 48-72h to reach 82.1%. The products of biodegradation were analyzed and the chemical pathway substantiated using chemical thermodynamic and energy release patterns. MTT assay confirmed that emanates are eco-friendly. Heat profile pattern and bioenergetics provide fundamental data for a feasible application in commercial level. Copyright © 2015 Elsevier Ltd. All rights reserved.

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish

PubMed Central

Giacomotto, J; Carroll, A P; Rinkwitz, S; Mowry, B; Cairns, M J; Becker, T S

2016-01-01

The neurodevelopmentally regulated microRNA miR-137 was strongly implicated as risk locus for schizophrenia in the most recent genome wide association study coordinated by the Psychiatric Genome Consortium (PGC). This molecule is highly conserved in vertebrates enabling the investigation of its function in the developing zebrafish. We utilized this model system to achieve overexpression and suppression of miR-137, both transiently and stably through transgenesis. While miR-137 overexpression was not associated with an observable specific phenotype, downregulation by antisense morpholino and/or transgenic expression of miR-sponge RNA induced significant impairment of both embryonic and larval touch-sensitivity without compromising overall anatomical development. We observed miR-137 expression and activity in sensory neurons including Rohon–Beard neurons and dorsal root ganglia, two neuronal cell types that confer touch-sensitivity in normal zebrafish, suggesting a role of these cell types in the observed phenotype. The lack of obvious anatomical or histological pathology in these cells, however, suggested that subtle axonal network defects or a change in synaptic function and neural connectivity might be responsible for the behavioral phenotype rather than a change in the cellular morphology or neuroanatomy. PMID:27219344

25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

Code of Federal Regulations, 2010 CFR

2010-04-01

... requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT... minimum standards for Tribe/Consortium management systems? Yes, the Tribe/Consortium must maintain...

25 CFR 1000.169 - How does a Tribe/Consortium initiate the information phase?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false How does a Tribe/Consortium initiate the information... of Initial Annual Funding Agreements § 1000.169 How does a Tribe/Consortium initiate the information phase? A Tribe/Consortium initiates the information phase by submitting a letter of interest to the...

25 CFR 1000.169 - How does a Tribe/Consortium initiate the information phase?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium initiate the information... of Initial Annual Funding Agreements § 1000.169 How does a Tribe/Consortium initiate the information phase? A Tribe/Consortium initiates the information phase by submitting a letter of interest to the...

77 FR 8252 - The International Consortium of Energy Managers; Notice of Preliminary Permit Application...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-14

... International Consortium of Energy Managers; Notice of Preliminary Permit Application Accepted for Filing and... Consortium of Energy Managers filed an application, pursuant to section 4(f) of the Federal Power Act (FPA...: Rexford Wait, International Consortium of Energy Managers, 2416 Cades Way, Vista, CA 92083; (760) 599-0086...

Biodegradation of phenanthrene in bioaugmented microcosm by consortium ASP developed from coastal sediment of Alang-Sosiya ship breaking yard.

PubMed

Patel, Vilas; Patel, Janki; Madamwar, Datta

2013-09-15

A phenanthrene-degrading bacterial consortium (ASP) was developed using sediment from the Alang-Sosiya shipbreaking yard at Gujarat, India. 16S rRNA gene-based molecular analyses revealed that the bacterial consortium consisted of six bacterial strains: Bacillus sp. ASP1, Pseudomonas sp. ASP2, Stenotrophomonas maltophilia strain ASP3, Staphylococcus sp. ASP4, Geobacillus sp. ASP5 and Alcaligenes sp. ASP6. The consortium was able to degrade 300 ppm of phenanthrene and 1000 ppm of naphthalene within 120 h and 48 h, respectively. Tween 80 showed a positive effect on phenanthrene degradation. The consortium was able to consume maximum phenanthrene at the rate of 46 mg/h/l and degrade phenanthrene in the presence of other petroleum hydrocarbons. A microcosm study was conducted to test the consortium's bioremediation potential. Phenanthrene degradation increased from 61% to 94% in sediment bioaugmented with the consortium. Simultaneously, bacterial counts and dehydrogenase activities also increased in the bioaugmented sediment. These results suggest that microbial consortium bioaugmentation may be a promising technology for bioremediation. Copyright © 2013 Elsevier Ltd. All rights reserved.

The Virginia Generalist Initiative: Lessons Learned in a Statewide Consortium.

ERIC Educational Resources Information Center

Morse, R. Michael; Plungas, Gay S.; Duke, Debra; Rollins, Lisa K.; Barnes, H. Verdain; Brinson, Betsy K.; Martindale, James R.; Marsland, David W.

1999-01-01

To increase supply of generalist physicians, three state-supported Virginia medical schools formed a partnership with governmental stakeholders in the Generalist Physician Initiative. Lessons learned concerning stakeholder participation in planning, shared philosophical commitment, support for risk-taking, attitudes toward change, and trust are…

US LAND-COVER MONITORING AND DETECTION OF CHANGES IN SCALE AND CONTEXT OF FOREST

EPA Science Inventory

Disparate land-cover mapping programs, previously focused solely on mission-oriented goals, have organized themselves as the Multi-Resolution Land Characteristics (MRLC) Consortium with a unified goal of producing land-cover nationwide at routine intervals. Under MRLC, United Sta...

WILLAMETTE RIVER BASIN TRAJECTORIES OF ENVIRONMENTAL AND ECOLOGICAL CHANGE: A PLANNING ATLAS

EPA Science Inventory

The Pacific Northwest Ecosystem Research Consortium, consisting of scientists at EPA-WED, Oregon State University, and the University of Oregon, completed a planning atlas for the Willamette River Basin in western Oregon. The atlas describes ecological conditions and human activ...

Planning and evaluating mental health services in low- and middle-income countries using theory of change

PubMed Central

Breuer, Erica; De Silva, Mary J.; Shidaye, Rahul; Petersen, Inge; Nakku, Juliet; Jordans, Mark J. D.; Fekadu, Abebaw; Lund, Crick

2016-01-01

Background There is little practical guidance on how contextually relevant mental healthcare plans (MHCPs) can be developed in low-resource settings. Aims To describe how theory of change (ToC) was used to plan the development and evaluation of MHCPs as part of the PRogramme for Improving Mental health carE (PRIME). Method ToC development occurred in three stages: (a) development of a cross-country ToC by 15 PRIME consortium members; (b) development of country-specific ToCs in 13 workshops with a median of 15 (interquartile range 13–22) stakeholders per workshop; and (c) review and refinement of the cross-country ToC by 18 PRIME consortium members. Results One cross-country and five district ToCs were developed that outlined the steps required to improve outcomes for people with mental disorders in PRIME districts. Conclusions ToC is a valuable participatory method that can be used to develop MHCPs and plan their evaluation. PMID:26447178

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chamberlain, S.Z.

Sterling Chemicals is a large chemical manufacturing company located in Texas City, Texas. Formerly a Monsanto plant, the facility was purchased in 1986 as a leveraged buy out by the Sterling Group of Houston, Texas. Total plant manufacturing area is 243 acres with 20 acres of greenbelt adjacent to the plant. The facility manufactures numerous intermediate chemical products: styrene, acrylonitrile, lactic acid, acetic acid, phthalic anhydride, phthalate esters, tertiary burylamine, and in 1989 began manufacturing sodium cyanide. In the early 1980`s Sterling Chemicals, Inc., in concert with approximately twenty other corporations in America, formed a consortium to address the impendingmore » regulatory changes in the federal Underground Injection Control (UIC) program. Since that time, after numerous successful changes in the UIC regulatory program, the consortium, under the administrative support of the Chemical Manufacturers Association (CMA), had embarked upon an effort to correct a wrong in the way Class I injection wells are reported on the Toxic Release Inventory forms in order to gain public confidence in the EPA and State Regulation of Deepwell Injection.« less

Simulating social-ecological systems: the Island Digital Ecosystem Avatars (IDEA) consortium.

PubMed

Davies, Neil; Field, Dawn; Gavaghan, David; Holbrook, Sally J; Planes, Serge; Troyer, Matthias; Bonsall, Michael; Claudet, Joachim; Roderick, George; Schmitt, Russell J; Zettler, Linda Amaral; Berteaux, Véronique; Bossin, Hervé C; Cabasse, Charlotte; Collin, Antoine; Deck, John; Dell, Tony; Dunne, Jennifer; Gates, Ruth; Harfoot, Mike; Hench, James L; Hopuare, Marania; Kirch, Patrick; Kotoulas, Georgios; Kosenkov, Alex; Kusenko, Alex; Leichter, James J; Lenihan, Hunter; Magoulas, Antonios; Martinez, Neo; Meyer, Chris; Stoll, Benoit; Swalla, Billie; Tartakovsky, Daniel M; Murphy, Hinano Teavai; Turyshev, Slava; Valdvinos, Fernanda; Williams, Rich; Wood, Spencer

2016-01-01

Systems biology promises to revolutionize medicine, yet human wellbeing is also inherently linked to healthy societies and environments (sustainability). The IDEA Consortium is a systems ecology open science initiative to conduct the basic scientific research needed to build use-oriented simulations (avatars) of entire social-ecological systems. Islands are the most scientifically tractable places for these studies and we begin with one of the best known: Moorea, French Polynesia. The Moorea IDEA will be a sustainability simulator modeling links and feedbacks between climate, environment, biodiversity, and human activities across a coupled marine-terrestrial landscape. As a model system, the resulting knowledge and tools will improve our ability to predict human and natural change on Moorea and elsewhere at scales relevant to management/conservation actions.

25 CFR 1000.425 - How does a Tribe/Consortium request an informal conference?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false How does a Tribe/Consortium request an informal... INDIAN SELF-DETERMINATION AND EDUCATION ACT Appeals § 1000.425 How does a Tribe/Consortium request an informal conference? The Tribe/Consortium shall file its request for an informal conference with the office...

25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... Miscellaneous Provisions § 1000.396 Does a Tribe/Consortium have additional ongoing requirements to maintain...

25 CFR 1000.222 - How does a Tribe/Consortium obtain a waiver?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium obtain a waiver? 1000.222...-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.222 How does a Tribe/Consortium obtain a waiver? To obtain a waiver, the Tribe/Consortium must: (a) Submit a written request from the designated Tribal...

25 CFR 1000.333 - How does a Tribe/Consortium retrocede a program?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium retrocede a program? 1000.333...-DETERMINATION AND EDUCATION ACT Retrocession § 1000.333 How does a Tribe/Consortium retrocede a program? The Tribe/Consortium must submit: (a) A written notice to: (1) The Office of Self-Governance for BIA...

25 CFR 1000.425 - How does a Tribe/Consortium request an informal conference?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium request an informal... INDIAN SELF-DETERMINATION AND EDUCATION ACT Appeals § 1000.425 How does a Tribe/Consortium request an informal conference? The Tribe/Consortium shall file its request for an informal conference with the office...

25 CFR 1000.400 - Can a Tribe/Consortium retain savings from programs?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Can a Tribe/Consortium retain savings from programs? 1000...-DETERMINATION AND EDUCATION ACT Miscellaneous Provisions § 1000.400 Can a Tribe/Consortium retain savings from programs? Yes, for BIA programs, the Tribe/Consortium may retain savings for each fiscal year during which...

25 CFR 1000.315 - When must the Tribe/Consortium return funds to the Department?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false When must the Tribe/Consortium return funds to the... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.315 When must the Tribe/Consortium return funds to the Department? The Tribe/Consortium must repay funds to the Department as soon as practical...

25 CFR 1000.333 - How does a Tribe/Consortium retrocede a program?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false How does a Tribe/Consortium retrocede a program? 1000.333...-DETERMINATION AND EDUCATION ACT Retrocession § 1000.333 How does a Tribe/Consortium retrocede a program? The Tribe/Consortium must submit: (a) A written notice to: (1) The Office of Self-Governance for BIA...

25 CFR 1000.315 - When must the Tribe/Consortium return funds to the Department?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false When must the Tribe/Consortium return funds to the... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.315 When must the Tribe/Consortium return funds to the Department? The Tribe/Consortium must repay funds to the Department as soon as practical...

Metro-Minnesota Community Clinical Oncology Program (MM-CCOP) | Division of Cancer Prevention

Cancer.gov

The Metro-Minnesota Community Clinical Oncology (MMCCOP) program has a long-standing history which clearly demonstrates the success of the consortium, as demonstrated by both the ongoing commitment of the original consortium members and the growth of the consortium from 1979 through 2014. The MMCCOP consortium represents an established community program base which began in

NET-Works: Linking families, communities and primary care to prevent obesity in preschool-age children.

PubMed

Sherwood, Nancy E; French, Simone A; Veblen-Mortenson, Sara; Crain, A Lauren; Berge, Jerica; Kunin-Batson, Alicia; Mitchell, Nathan; Senso, Meghan

2013-11-01

Obesity prevention in children offers a unique window of opportunity to establish healthful eating and physical activity behaviors to maintain a healthful body weight and avoid the adverse proximal and distal long-term health consequences of obesity. Given that obesity is the result of a complex interaction between biological, behavioral, family-based, and community environmental factors, intervention at multiple levels and across multiple settings is critical for both short- and long-term effectiveness. The Minnesota NET-Works (Now Everybody Together for Amazing and Healthful Kids) study is one of four obesity prevention and/or treatment trials that are part of the Childhood Obesity Prevention and Treatment (COPTR) Consortium. The goal of the NET-Works study is to evaluate an intervention that integrates home, community, primary care and neighborhood strategies to promote healthful eating, activity patterns, and body weight among low income, racially/ethnically diverse preschool-age children. Critical to the success of this intervention is the creation of linkages among the settings to support parents in making home environment and parenting behavior changes to foster healthful child growth. Five hundred racially/ethnically diverse, two-four year old children and their parent or primary caregiver will be randomized to the multi-component intervention or to a usual care comparison group for a three-year period. This paper describes the study design, measurement and intervention protocols, and statistical analysis plan for the NET-Works trial. © 2013 Elsevier Inc. All rights reserved.

International Lymphoma Epidemiology Consortium

Cancer.gov

The InterLymph Consortium, or formally the International Consortium of Investigators Working on Non-Hodgkin's Lymphoma Epidemiologic Studies, is an open scientific forum for epidemiologic research in non-Hodgkin's lymphoma.

A Critical Review of Strategic Planning: Panacea for Public Education?

ERIC Educational Resources Information Center

Beach, Robert H.; Lindahl, Ron

2004-01-01

Many states, accrediting agencies, and the Interstate School Leaders Licensure Consortium have policies and standards mandating strategic planning for public schools. Planning in schools has become synonymous with strategic planning. However, alternative approaches to change exist that offer more effective solutions to school improvement. School…

Completion of the National Land Cover Database (NLCD) 1992-2001 Land Cover Change Retrofit Product

EPA Science Inventory

The Multi-Resolution Land Characteristics Consortium has supported the development of two national digital land cover products: the National Land Cover Dataset (NLCD) 1992 and National Land Cover Database (NLCD) 2001. Substantial differences in imagery, legends, and methods betwe...

Establishment of a Multi-State Experiential Pharmacy Program Consortium

PubMed Central

Unterwagner, Whitney L.; Byrd, Debbie C.

2008-01-01

In 2002, a regional consortium was created for schools and colleges of pharmacy in Georgia and Alabama to assist experiential education faculty and staff members in streamlining administrative processes, providing required preceptor development, establishing a professional network, and conducting scholarly endeavors. Five schools and colleges of pharmacy with many shared experiential practice sites formed a consortium to help experiential faculty and staff members identify, discuss, and solve common experience program issues and challenges. During its 5 years in existence, the Southeastern Pharmacy Experiential Education Consortium has coordinated experiential schedules, developed and implemented uniform evaluation tools, coordinated site and preceptor development activities, established a work group for educational research and scholarship, and provided opportunities for networking and professional development. Several consortium members have received national recognition for their individual experiential education accomplishments. Through the activities of a regional consortium, members have successfully developed programs and initiatives that have streamlined administrative processes and have the potential to improve overall quality of experiential education programs. Professionally, consortium activities have resulted in 5 national presentations. PMID:18698386

A Process Research Framework: The International Process Research Consortium

DTIC Science & Technology

2006-12-01

projects ? 52 Theme P | IPRC Framework 5 P-30 How should a process for collaborative development be formulated? The development at different companies...requires some process for the actual collaboration . How should it be handled? P-31 How do we handle change? Requirements change during development ...source projects employ a single-site development model in which there is no large community of testers but rather a single-site small group

Meta-Analyses of Genome-Wide Association Data Hold New Promise for Addiction Genetics.

PubMed

Agrawal, Arpana; Edenberg, Howard J; Gelernter, Joel

2016-09-01

Meta-analyses of genome-wide association study data have begun to lead to promising new discoveries for behavioral and psychiatrically relevant phenotypes (e.g., schizophrenia, educational attainment). We outline how this methodology can similarly lead to novel discoveries in genomic studies of substance use disorders, and discuss challenges that will need to be overcome to accomplish this goal. We illustrate our approach with the work of the newly established Substance Use Disorders workgroup of the Psychiatric Genomics Consortium.

Southeast Clinical Oncology Research Consortium, Inc. (SCOR) | Division of Cancer Prevention

Cancer.gov

The SCCC-Upstate is a merger of two successful legacy CCOPs known as Southeast Cancer Control Consortium, Inc. (SCCC) and Upstate Carolina (hereafter the Consortium) comprised of 23 components and 63 sub-components, located in a five-state area of the Southeast US (GA, NC, SC, TN, and VA) with a nonclinical Administrative Office (AO) in Winston-Salem, NC. The Consortium

25 CFR 1000.390 - How can a Tribe/Consortium hire a Federal employee to help implement an AFA?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false How can a Tribe/Consortium hire a Federal employee to help implement an AFA? 1000.390 Section 1000.390 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN... Tribe/Consortium hire a Federal employee to help implement an AFA? If a Tribe/Consortium chooses to hire...

25 CFR 1000.390 - How can a Tribe/Consortium hire a Federal employee to help implement an AFA?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false How can a Tribe/Consortium hire a Federal employee to help implement an AFA? 1000.390 Section 1000.390 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN... Tribe/Consortium hire a Federal employee to help implement an AFA? If a Tribe/Consortium chooses to hire...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

AFT-QuEST Consortium Yearbook. Proceedings of the QuEST Consortium (April 2-6, 1972).

ERIC Educational Resources Information Center

American Federation of Teachers, Washington, DC.

This book contains the proceedings from the QuEST Consortium held on April 2-6, 1972, which focused on problems of method and technique in teaching as well as on resource organization. The program schedule for the Consortium is presented with the following goals: (a) investigation of educational policy issues, action programs, and projects and (b)…

Effect of inoculation with white-rot fungi and fungal consortium on the composting efficiency of municipal solid waste.

PubMed

Voběrková, Stanislava; Vaverková, Magdalena D; Burešová, Alena; Adamcová, Dana; Vršanská, Martina; Kynický, Jindřich; Brtnický, Martin; Adam, Vojtěch

2017-03-01

An investigation was carried out on the effect of inoculation methods on the compost of an organic fraction of municipal solid waste. Three types of white-rot fungi (Phanerochaete chrysosporium, Trametes versicolor and Fomes fomentarius), and a consortium of these fungi, were used. The study assessed their influence on microbial enzymatic activities and the quality of the finished compost. It was found that the addition of white-rot fungi to municipal solid waste (after 37days of composting) could be a useful strategy for enhancing the properties of the final compost product. In comparison with the control sample (compost without inoculation), it accelerates degradation of solid waste as indicated by changes in C/N, electrical conductivity and pH. However, the effectiveness of waste degradation and compost maturation depends on the type of microorganism used for inoculation. The presence of inoculants, such as Trametes versicolor and Fomes fomentarius, led to a higher degrading ratio and a better degree of maturity. This resulted in an increase of enzymatic activities (especially dehydrogenase and protease) and a germination index in comparison with inoculation using Phanerochaete chrysosporium or a consortium of fungi. Copyright © 2016 Elsevier Ltd. All rights reserved.

Enhancement of Health Research Capacity in Nigeria through North-South and In-Country Partnerships

PubMed Central

Olaleye, David O.; Odaibo, Georgina N.; Carney, Paula; Agbaji, Oche; Sagay, Atiene S.; Muktar, Haruna; Akinyinka, Olusegun O.; Omigbodun, Akinyinka O.; Ogunniyi, Adesola; Gashau, Wadzani; Akanmu, Sulaimon; Ogunsola, Folasade; Chukwuka, Chinwe; Okonkwo, Prosper I.; Meloni, Seema T.; Adewole, Isaac; Kanki, Phyllis J.; Murphy, Robert L.

2014-01-01

Research productivity in Sub-Saharan Africa has the potential to affect teaching, student quality, faculty career development, and translational country-relevant research as it has in developed countries. Nigeria is the most populous country in Africa, with an academic infrastructure that includes 129 universities and 45 medical schools; however, despite the size, the country has unacceptably poor health status indicators. To further develop the research infrastructure in Nigeria, faculty and research career development topics were identified within the six Nigerian universities of the nine institutions of the Medical Education Partnership Initiative in Nigeria (MEPIN) consortium. The consortium identified a training model that incorporated multi-institutional “train the trainers” programs at the University of Ibadan, followed by replication at the other MEPIN universities. More than 140 in-country trainers subsequently presented nine courses to more than 1,600 faculty, graduate students, and resident doctors throughout the consortium during the program’s first three years (2011–2013). This model has fostered a new era of collaboration among the major Nigerian research universities, which now have increased capacity for collaborative research initiatives and improved research output. These changes, in turn, have the potential to improve the nation’s health outcomes. PMID:25072590

Computational Astrophysics Consortium 3 - Supernovae, Gamma-Ray Bursts and Nucleosynthesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woosley, Stan

Final project report for UCSC's participation in the Computational Astrophysics Consortium - Supernovae, Gamma-Ray Bursts and Nucleosynthesis. As an appendix, the report of the entire Consortium is also appended.

Completion of the 2006 National Land Cover Database Update for the Conterminous United States

EPA Science Inventory

Under the organization of the Multi-Resolution Land Characteristics (MRLC) Consortium, the National Land Cover Database (NLCD) has been updated to characterize both land cover and land cover change from 2001 to 2006. An updated version of NLCD 2001 (Version 2.0) is also provided....

Blessed Unrest: The Power of Unreasonable People to Change the World

ERIC Educational Resources Information Center

Marshall, Stephanie Pace

2008-01-01

In this keynote address presented at the 2008 National Consortium for Specialized Secondary Schools of Mathematics, Science and Technology (NCSSSMST) Professional Conference, Stephanie Marshall describes what is needed to transform STEM education in today's world. While such an endeavor will take multiple systemic actions, here Marshall focuses on…

Goddard Earth Sciences and Technology Center (GEST)

NASA Technical Reports Server (NTRS)

2002-01-01

This document summarizes the activities of the Goddard Earth Sciences and Technology Center (GEST), a consortium of scientists and engineers led by the University of Maryland, Baltimore County (UMBC), during the contract reporting period. Topics covered include: new programs, eligibility and selection criteria, Goddard Coastal Research Graduate Fellowship Program and staffing changes.

Educating the New American Student.

ERIC Educational Resources Information Center

Renaissance Group, Cedar Falls, IA.

The Renaissance Group, a consortium of 19 universities, was created in 1989 to improve the education of teachers and to facilitate efforts to reform teacher education nationally. One of the group's first priorities has been to analyze the growth of several largely environmental conditions such as the changing structure of the American family and…

Changing Workloads and Productivity in Interlibrary Loan.

ERIC Educational Resources Information Center

Paine, Nancy E.; Ward, John

1996-01-01

Compares interlibrary loan data from a 1995 survey of Greater Midwest Research Library Consortium and Association of Research Libraries members with a 1989 survey. Shows an increase in transaction to staff ratio and a negative correlation between transaction to staff ratio and lending fill rate. Relates factors affecting productivity, such as…

Changes in Teachers' Beliefs and Practices in Technology-Rich Classrooms.

ERIC Educational Resources Information Center

Dwyer, David C.; And Others

1991-01-01

The Apple Classrooms of Tomorrow (ACOT) project is a flexible consortium of researchers, educators, students, and parents who have worked collaboratively to create and study innovative learning environments since 1985. ACOT classrooms are true multimedia environments where students move from competitive work patterns toward collaborative ones. (10…

Changes in classification of genetic variants in BRCA1 and BRCA2.

PubMed

Kast, Karin; Wimberger, Pauline; Arnold, Norbert

2018-02-01

Classification of variants of unknown significance (VUS) in the breast cancer genes BRCA1 and BRCA2 changes with accumulating evidence for clinical relevance. In most cases down-staging towards neutral variants without clinical significance is possible. We searched the database of the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) for changes in classification of genetic variants as an update to our earlier publication on genetic variants in the Centre of Dresden. Changes between 2015 and 2017 were recorded. In the group of variants of unclassified significance (VUS, Class 3, uncertain), only changes of classification towards neutral genetic variants were noted. In BRCA1, 25% of the Class 3 variants (n = 2/8) changed to Class 2 (likely benign) and Class 1 (benign). In BRCA2, in 50% of the Class 3 variants (n = 16/32), a change to Class 2 (n = 10/16) or Class 1 (n = 6/16) was observed. No change in classification was noted in Class 4 (likely pathogenic) and Class 5 (pathogenic) genetic variants in both genes. No up-staging from Class 1, Class 2 or Class 3 to more clinical significance was observed. All variants with a change in classification in our cohort were down-staged towards no clinical significance by a panel of experts of the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC). Prevention in families with Class 3 variants should be based on pedigree based risks and should not be guided by the presence of a VUS.

77 FR 43237 - Genome in a Bottle Consortium-Work Plan Review Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-24

... in human whole genome variant calls. A principal motivation for this consortium is to enable... principal motivation for this consortium is to enable science-based regulatory oversight of clinical...

Midwest Transportation Consortium : 2003-2004 annual report.

DOT National Transportation Integrated Search

2004-01-01

Introduction: The Midwest Transportation Consortium (MTC) recently completed its fifth year : of operation. In doing so, the consortium has established itself as an effective : network that promotes the education of future transportation professional...

Consortium for military LCD display procurement

NASA Astrophysics Data System (ADS)

Echols, Gregg

2002-08-01

International Display Consortium (IDC) is the joining together of display companies to combined their buying power and obtained favorable terms with a major LCD manufacturer. Consolidating the buying power and grouping the demand enables the rugged display industry of avionics, ground vehicles, and ship based display manufacturers to have unencumbered access to high performance AMLCDs while greatly reducing risk and lowering cost. With an unrestricted supply of AMLCD displays, the consortium members have total control of their risk, cost, deliveries and added value partners. Every display manufacturer desires a very close relationship with a display vender. With IDC each consortium member achieves a close relationship. Consortium members enjoy cost effective access to high performance, industry standard sized LCD panels, and modified commercial displays with 100 degree C clearing points and portrait configurations. Consortium members also enjoy proposal support, technical support and long-term support.

Biodegradability of fluoxetine, mefenamic acid, and metoprolol using different microbial consortiums.

PubMed

Velázquez, Yolanda Flores; Nacheva, Petia Mijaylova

2017-03-01

The biodegradation of fluoxetine, mefenamic acid, and metoprolol using ammonium-nitrite-oxidizing consortium, nitrite-oxidizing consortium, and heterotrophic biomass was evaluated in batch tests applying different retention times. The ammonium-nitrite-oxidizing consortium presented the highest biodegradation percentages for mefenamic acid and metoprolol, of 85 and 64% respectively. This consortium was also capable to biodegrade 79% of fluoxetine. The heterotrophic consortium showed the highest ability to biodegrade fluoxetine reaching 85%, and it also had a high potential for biodegrading mefenamic acid and metoprolol, of 66 and 58% respectively. The nitrite-oxidizing consortium presented the lowest biodegradation of the three pharmaceuticals, of less than 48%. The determination of the selected pharmaceuticals in the dissolved phase and in the biomass indicated that biodegradation was the major removal mechanism of the three compounds. Based on the obtained results, the biodegradation kinetics was adjusted to pseudo-first-order for the three pharmaceuticals. The values of k biol for fluoxetine, mefenamic acid, and metoprolol determined with the three consortiums indicated that ammonium-nitrite-oxidizing and heterotrophic biomass allow a partial biodegradation of the compounds, while no substantial biodegradation can be expected using nitrite-oxidizing consortium. Metoprolol was the less biodegradable compound. The sorption of fluoxetine and mefenamic acid onto biomass had a significant contribution for their removal (6-14%). The lowest sorption coefficients were obtained for metoprolol indicating that the sorption onto biomass is poor (3-4%), and the contribution of this process to the global removal can be neglected.

ICONE: An International Consortium of Neuro Endovascular Centres.

PubMed

Raymond, J; White, P; Kallmes, D F; Spears, J; Marotta, T; Roy, D; Guilbert, F; Weill, A; Nguyen, T; Molyneux, A J; Cloft, H; Cekirge, S; Saatci, I; Bracard, S; Meder, J F; Moret, J; Cognard, C; Qureshi, A I; Turk, A S; Berenstein, A

2008-06-30

The proliferation of new endovascular devices and therapeutic strategies calls for a prudentand rational evaluation of their clinical benefit. This evaluation must be done in an effective manner and in collaboration with industry. Such research initiative requires organisation a land methodological support to survive and thrive in a competitive environment. We propose the formation of an international consortium, an academic alliance committed to the pursuit of effective neurovascular therapies. Such a consortium would be dedicated to the designand execution of basic science, device developmentand clinical trials. The Consortium is owned and operated by its members. Members are international leaders in neurointerventional research and clinical practice. The Consortium brings competency, knowledge, and expertise to industry as well as to its membership across aspectrum of research initiatives such as: expedited review of clinical trials, protocol development, surveys and systematic reviews; laboratory expertise and support for research design and grant applications to public agencies. Once objectives and protocols are approved, the Consortium provides a stable network of centers capable of timely realization of clinical trials or pre clinical investigations in an optimal environment. The Consortium is a non-profit organization. The potential revenue generated from clientsponsored financial agreements will be redirected to the academic and research objectives of the organization. The Consortium wishes to work inconcert with industry, to support emerging trends in neurovascular therapeutic development. The Consortium is a realistic endeavour optimally structured to promote excellence through scientific appraisal of our treatments, and to accelerate technical progress while maximizing patients' safety and welfare.

Photovoltaic Manufacturing Consortium (PVMC) – Enabling America’s Solar Revolution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Metacarpa, David

The U.S. Photovoltaic Manufacturing Consortium (US-PVMC) is an industry-led consortium which was created with the mission to accelerate the research, development, manufacturing, field testing, commercialization, and deployment of next-generation solar photovoltaic technologies. Formed as part of the U.S. Department of Energy's (DOE) SunShot initiative, and headquartered in New York State, PVMC is managed by the State University of New York Polytechnic Institute (SUNY Poly) at the Colleges of Nanoscale Science and Engineering. PVMC is a hybrid of industry-led consortium and manufacturing development facility, with capabilities for collaborative and proprietary industry engagement. Through its technology development programs, advanced manufacturing development facilities,more » system demonstrations, and reliability and testing capabilities, PVMC has demonstrated itself to be a recognized proving ground for innovative solar technologies and system designs. PVMC comprises multiple locations, with the core manufacturing and deployment support activities conducted at the Solar Energy Development Center (SEDC), and the core Si wafering and metrology technologies being headed out of the University of Central Florida. The SEDC provides a pilot line for proof-of-concept prototyping, offering critical opportunities to demonstrate emerging concepts in PV manufacturing, such as evaluations of innovative materials, system components, and PV system designs. The facility, located in Halfmoon NY, encompasses 40,000 square feet of dedicated PV development space. The infrastructure and capabilities housed at PVMC includes PV system level testing at the Prototype Demonstration Facility (PDF), manufacturing scale cell & module fabrication at the Manufacturing Development Facility (MDF), cell and module testing, reliability equipment on its PV pilot line, all integrated with a PV performance database and analytical characterizations for PVMC and its partners test and commercial arrays. Additional development and deployment support are also housed at the SEDC, such as cost modeling and cost model based development activities for PV and thin film modules, components, and system level designs for reduced LCOE through lower installation hardware costs, labor reductions, soft costs and reduced operations and maintenance costs. The progression of the consortium activities started with infrastructure and capabilities build out focused on CIGS thin film photovoltaics, with a particular focus on flexible cell and module production. As marketplace changes and partners objectives shifted, the consortium shifted heavily towards deployment and market pull activities including Balance of System, cost modeling, and installation cost reduction efforts along with impacts to performance and DER operational costs. The consortium consisted of a wide array of PV supply chain companies from equipment and component suppliers through national developers and installers with a particular focus on commercial scale deployments (typically 25 to 2MW installations). With DOE funding ending after the fifth budget period, the advantages and disadvantages of such a consortium is detailed along with potential avenues for self-sustainability is reviewed.« less

25 CFR 1000.54 - How will a Tribe/Consortium know whether or not it has been selected to receive an advance...

Code of Federal Regulations, 2010 CFR

2010-04-01

...) Planning and Negotiation Grants Advance Planning Grant Funding § 1000.54 How will a Tribe/Consortium know... Director will notify the Tribe/Consortium by letter whether it has been selected to receive an advance... 25 Indians 2 2010-04-01 2010-04-01 false How will a Tribe/Consortium know whether or not it has...

Biodegradation of different petroleum hydrocarbons by free and immobilized microbial consortia.

PubMed

Shen, Tiantian; Pi, Yongrui; Bao, Mutai; Xu, Nana; Li, Yiming; Lu, Jinren

2015-12-01

The efficiencies of free and immobilized microbial consortia in the degradation of different types of petroleum hydrocarbons were investigated. In this study, the biodegradation rates of naphthalene, phenanthrene, pyrene and crude oil reached about 80%, 30%, 56% and 48% under the optimum environmental conditions of free microbial consortia after 7 d. We evaluated five unique co-metabolic substances with petroleum hydrocarbons, α-lactose was the best co-metabolic substance among glucose, α-lactose, soluble starch, yeast powder and urea. The orthogonal biodegradation analysis results showed that semi-coke was the best immobilized carrier followed by walnut shell and activated carbon. Meanwhile, the significance of various factors that contribute to the biodegradation of semi-coke immobilized microbial consortia followed the order of: α-lactose > semi-coke > sodium alginate > CaCl2. Moreover, the degradation rate of the immobilized microbial consortium (47%) was higher than that of a free microbial consortium (26%) under environmental conditions such as the crude oil concentration of 3 g L(-1), NaCl concentration of 20 g L(-1), pH at 7.2-7.4 and temperature of 25 °C after 5 d. SEM and FTIR analyses revealed that the structure of semi-coke became more porous and easily adhered to the microbial consortium; the functional groups (e.g., hydroxy and phosphate) were identified in the microbial consortium and were changed by immobilization. This study demonstrated that the ability of microbial adaptation to the environment can be improved by immobilization which expands the application fields of microbial remediation.

Oil Production by a Consortium of Oleaginous Microorganisms grown on primary effluent wastewater

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hall, Jacqueline; Hetrick, Mary; French, Todd

Municipal wastewater could be a potential growth medium that has not been considered for cultivating oleaginous microorganisms. This study is designed to determine if a consortium of oleaginous microorganism can successfully compete for carbon and other nutrients with the indigenous microorganisms contained in primary effluent wastewater. RESULTS: The oleaginous consortium inoculated with indigenous microorganisms reached stationary phase within 24 h, reaching a maximum cell concentration of 0.58 g L -1. Water quality post-oleaginous consortium growth reached a maximum chemical oxygen demand (COD) reduction of approximately 81%, supporting the consumption of the glucose within 8 h. The oleaginous consortium increased themore » amount of oil produced per gram by 13% compared with indigenous microorganisms in raw wastewater. Quantitative polymerase chain reaction (qPCR) results show a substantial population increase in bacteria within the first 24 h when the consortium is inoculated into raw wastewater. This result, along with the fatty acid methyl esters (FAMEs) results, suggests that conditions tested were not sufficient for the oleaginous consortium to compete with the indigenous microorganisms.« less

Biostimulation of metal-resistant microbial consortium to remove zinc from contaminated environments.

PubMed

Mejias Carpio, Isis E; Franco, Diego Castillo; Zanoli Sato, Maria Inês; Sakata, Solange; Pellizari, Vivian H; Seckler Ferreira Filho, Sidney; Frigi Rodrigues, Debora

2016-04-15

Understanding the diversity and metal removal ability of microorganisms associated to contaminated aquatic environments is essential to develop metal remediation technologies in engineered environments. This study investigates through 16S rRNA deep sequencing the composition of a biostimulated microbial consortium obtained from the polluted Tietê River in São Paulo, Brazil. The bacterial diversity of the biostimulated consortium obtained from the contaminated water and sediment was compared to the original sample. The results of the comparative sequencing analyses showed that the biostimulated consortium and the natural environment had γ-Proteobacteria, Firmicutes, and uncultured bacteria as the major classes of microorganisms. The consortium optimum zinc removal capacity, evaluated in batch experiments, was achieved at pH=5 with equilibrium contact time of 120min, and a higher Zn-biomass affinity (KF=1.81) than most pure cultures previously investigated. Analysis of the functional groups found in the consortium demonstrated that amine, carboxyl, hydroxyl, and phosphate groups present in the consortium cells were responsible for zinc uptake. Copyright © 2016 Elsevier B.V. All rights reserved.

GAS STORAGE TECHNOLGOY CONSORTIUM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert W. Watson

2004-04-23

Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services, and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feetmore » (TCF) over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is critical in meeting the needs of these new markets. In order to address the gas storage needs of the natural gas industry, an industry-driven consortium was created--the Gas Storage Technology Consortium (GSTC). The objective of the GSTC is to provide a means to accomplish industry-driven research and development designed to enhance operational flexibility and deliverability of the Nation's gas storage system, and provide a cost effective, safe, and reliable supply of natural gas to meet domestic demand. To accomplish this objective, the project is divided into three phases that are managed and directed by the GSTC Coordinator. Base funding for the consortium is provided by the U.S. Department of Energy (DOE). In addition, funding is anticipated from the Gas Technology Institute (GTI). The first phase, Phase 1A, was initiated on September 30, 2003, and is scheduled for completion on March 31, 2004. Phase 1A of the project includes the creation of the GSTC structure, development of constitution (by-laws) for the consortium, and development and refinement of a technical approach (work plan) for deliverability enhancement and reservoir management. This report deals with the first 3-months of the project and encompasses the period September 30, 2003, through December 31, 2003. During this 3-month period, the first meeting of individuals representing the storage industry, universities and the Department of energy was held. The purpose of this meeting was to initiate the dialogue necessary to for the creation and adoption of a constitution that would be used to govern the activities of the consortium.« less

GAS STORAGE TECHNOLOGY CONSORTIUM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert W. Watson

2004-04-17

Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services, and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feetmore » (TCF) over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is critical in meeting the needs of these new markets. In order to address the gas storage needs of the natural gas industry, an industry-driven consortium was created--the Gas Storage Technology Consortium (GSTC). The objective of the GSTC is to provide a means to accomplish industry-driven research and development designed to enhance operational flexibility and deliverability of the Nation's gas storage system, and provide a cost effective, safe, and reliable supply of natural gas to meet domestic demand. To accomplish this objective, the project is divided into three phases that are managed and directed by the GSTC Coordinator. Base funding for the consortium is provided by the U.S. Department of Energy (DOE). In addition, funding is anticipated from the Gas Technology Institute (GTI). The first phase, Phase 1A, was initiated on September 30, 2003, and is scheduled for completion on March 31, 2004. Phase 1A of the project includes the creation of the GSTC structure, development of constitution (by-laws) for the consortium, and development and refinement of a technical approach (work plan) for deliverability enhancement and reservoir management. This report deals with the second 3-months of the project and encompasses the period December 31, 2003, through March 31, 2003. During this 3-month, the dialogue of individuals representing the storage industry, universities and the Department of energy was continued and resulted in a constitution for the operation of the consortium and a draft of the initial Request for Proposals (RFP).« less

ANNUAL REPORT For Calendar Year 2007 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2008-02-02

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 2006 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2007-04-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 2009 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2010-03-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 1996 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

1997-01-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

Midwest Transportation Consortium : 2006-2007 annual report.

DOT National Transportation Integrated Search

2007-01-01

Introduction: The Midwest Transportation Consortium (MTC) began year 8 by having the funding it receives from the Research and Innovative Technology Administration doubled, and by losing its regional grant to a consortium led by the University of Neb...

ANNUAL REPORT For Calendar Year 2008 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2009-04-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 2002 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2003-11-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 2003 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2005-09-22

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 2004 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2005-12-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 2001 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2002-12-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

ANNUAL REPORT For Calendar Year 2005 : NEW ENGLAND TRANSPORTATION CONSORTIUM

DOT National Transportation Integrated Search

2006-08-01

The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States. Through the Consortium, the states pool professional, academic and financial resources for transportation research ...

Results of a 2-year randomized, controlled obesity prevention trial: Effects on diet, activity and sleep behaviors in an at-risk young adult population.

PubMed

Laska, Melissa N; Lytle, Leslie A; Nanney, Marilyn S; Moe, Stacey G; Linde, Jennifer A; Hannan, Peter J

2016-08-01

Excess weight gain tends to occur in young adulthood. However, research examining effective weight-related interventions for this age group has been limited. As one of seven trials in the EARLY Trials consortium (Early Adult Reduction of weight through LifestYle intervention), the CHOICES Study (Choosing Healthy Options in College Environments and Settings) tested effects of a technology-integrated, young adult weight gain prevention intervention. It was a randomized controlled trial with assessments at baseline (2011) and 4-, 12- and 24-months post-intervention initiation and included 441 participants (ages 18-35) who were students at three Minnesota community colleges. The 24-month intervention included a 1-credit academic course and social networking and support online intervention. This analysis examined effects on 12 secondary behavioral outcomes across three domains: diet (fast food, sugary beverages, breakfast, at-home meal preparation), physical activity/screen time (minutes and energy expenditure in leisure time physical activity, television viewing, leisure time computer use) and sleep (hours of sleep, time required to fall asleep, days not getting enough rest, difficulty staying awake). The intervention resulted in significant reductions in fast food (p=0.007) but increases in difficulty staying awake (p=0.015). There was limited evidence of other behavior changes at 4months (0.05

Establishing a Consortium for the Study of Rare Diseases: The Urea Cycle Disorders Consortium

PubMed Central

Seminara, Jennifer; Tuchman, Mendel; Krivitzky, Lauren; Krischer, Jeffrey; Lee, Hye-Seung; LeMons, Cynthia; Baumgartner, Matthias; Cederbaum, Stephen; Diaz, George A.; Feigenbaum, Annette; Gallagher, Renata C.; Harding, Cary O.; Kerr, Douglas S.; Lanpher, Brendan; Lee, Brendan; Lichter-Konecki, Uta; McCandless, Shawn E.; Merritt, J. Lawrence; Oster-Granite, Mary Lou; Seashore, Margretta R.; Stricker, Tamar; Summar, Marshall; Waisbren, Susan; Yudkoff, Marc; Batshaw, Mark L.

2010-01-01

The Urea Cycle Disorders Consortium (UCDC) was created as part of a larger network established by the National Institutes of Health to study rare diseases. This paper reviews the UCDC’s accomplishments over the first six years, including how the Consortium was developed and organized, clinical research studies initiated, and the importance of creating partnerships with patient advocacy groups, philanthropic foundations and biotech and pharmaceutical companies. PMID:20188616

Northeast Artificial Intelligence Consortium (NAIC) Review of Technical Tasks. Volume 2, Part 2.

DTIC Science & Technology

1987-07-01

A-A19 774 NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUN (MIC) 1/5 YVIEN OF TEOICR. T.. (U) NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM SYRACUSE MY J...NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM (NAIC) *p,* ~ Review of Technical Tasks ,.. 12 PERSONAL AUTHOR(S) (See reverse) . P VI J.F. Allen, P.B. Berra...See reverse) /" I ABSTRACT (Coninue on ’.wrse if necessary and identify by block number) % .. *. -. ’ The Northeast Artificial Intelligence Consortium

Northeast Artificial Intelligence Consortium Annual Report. 1988 Interference Techniques for Knowledge Base Maintenance Using Logic Programming Methodologies. Volume 11

DTIC Science & Technology

1989-10-01

Northeast Aritificial Intelligence Consortium (NAIC). i Table of Contents Execu tive Sum m ary...o g~nIl ’vLr COPY o~ T- RADC-TR-89-259, Vol XI (of twelve) N Interim Report SOctober 1989 NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM ANNUAL REPORT...ORGANIZATION 6b. OFFICE SYMBOL 7a. NAME OF MONITORING ORGANIZATION Northeast Artificial (If applicable) Intelligence Consortium (NAIC) . Rome Air Development

Fidelity considerations in translational research: Eating As Treatment - a stepped wedge, randomised controlled trial of a dietitian delivered behaviour change counselling intervention for head and neck cancer patients undergoing radiotherapy.

PubMed

Beck, Alison Kate; Baker, Amanda; Britton, Ben; Wratten, Chris; Bauer, Judith; Wolfenden, Luke; Carter, Gregory

2015-10-15

The confidence with which researchers can comment on intervention efficacy relies on evaluation and consideration of intervention fidelity. Accordingly, there have been calls to increase the transparency with which fidelity methodology is reported. Despite this, consideration and/or reporting of fidelity methods remains poor. We seek to address this gap by describing the methodology for promoting and facilitating the evaluation of intervention fidelity in The EAT (Eating As Treatment) project: a multi-site stepped wedge randomised controlled trial of a dietitian delivered behaviour change counselling intervention to improve nutrition (primary outcome) in head and neck cancer patients undergoing radiotherapy. In accordance with recommendations from the National Institutes of Health Behaviour Change Consortium Treatment Fidelity Workgroup, we sought to maximise fidelity in this stepped wedge randomised controlled trial via strategies implemented from study design through to provider training, intervention delivery and receipt. As the EAT intervention is designed to be incorporated into standard dietetic consultations, we also address unique challenges for translational research. We offer a strong model for improving the quality of translational findings via real world application of National Institutes of Health Behaviour Change Consortium recommendations. Greater transparency in the reporting of behaviour change research is an important step in improving the progress and quality of behaviour change research. ACTRN12613000320752 (Date of registration 21 March 2013).

Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.

PubMed

Uzuner, Halil; Bauer, Rudolf; Fan, Tai-Ping; Guo, De-An; Dias, Alberto; El-Nezami, Hani; Efferth, Thomas; Williamson, Elizabeth M; Heinrich, Michael; Robinson, Nicola; Hylands, Peter J; Hendry, Bruce M; Cheng, Yung-Chi; Xu, Qihe

2012-04-10

GP-TCM is the 1st EU-funded Coordination Action consortium dedicated to traditional Chinese medicine (TCM) research. This paper aims to summarise the objectives, structure and activities of the consortium and introduces the position of the consortium regarding good practice, priorities, challenges and opportunities in TCM research. Serving as the introductory paper for the GP-TCM Journal of Ethnopharmacology special issue, this paper describes the roadmap of this special issue and reports how the main outputs of the ten GP-TCM work packages are integrated, and have led to consortium-wide conclusions. Literature studies, opinion polls and discussions among consortium members and stakeholders. By January 2012, through 3 years of team building, the GP-TCM consortium had grown into a large collaborative network involving ∼200 scientists from 24 countries and 107 institutions. Consortium members had worked closely to address good practice issues related to various aspects of Chinese herbal medicine (CHM) and acupuncture research, the focus of this Journal of Ethnopharmacology special issue, leading to state-of-the-art reports, guidelines and consensus on the application of omics technologies in TCM research. In addition, through an online survey open to GP-TCM members and non-members, we polled opinions on grand priorities, challenges and opportunities in TCM research. Based on the poll, although consortium members and non-members had diverse opinions on the major challenges in the field, both groups agreed that high-quality efficacy/effectiveness and mechanistic studies are grand priorities and that the TCM legacy in general and its management of chronic diseases in particular represent grand opportunities. Consortium members cast their votes of confidence in omics and systems biology approaches to TCM research and believed that quality and pharmacovigilance of TCM products are not only grand priorities, but also grand challenges. Non-members, however, gave priority to integrative medicine, concerned on the impact of regulation of TCM practitioners and emphasised intersectoral collaborations in funding TCM research, especially clinical trials. The GP-TCM consortium made great efforts to address some fundamental issues in TCM research, including developing guidelines, as well as identifying priorities, challenges and opportunities. These consortium guidelines and consensus will need dissemination, validation and further development through continued interregional, interdisciplinary and intersectoral collaborations. To promote this, a new consortium, known as the GP-TCM Research Association, is being established to succeed the 3-year fixed term FP7 GP-TCM consortium and will be officially launched at the Final GP-TCM Congress in Leiden, the Netherlands, in April 2012. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Automating linear accelerator quality assurance.

PubMed

Eckhause, Tobias; Al-Hallaq, Hania; Ritter, Timothy; DeMarco, John; Farrey, Karl; Pawlicki, Todd; Kim, Gwe-Ya; Popple, Richard; Sharma, Vijeshwar; Perez, Mario; Park, SungYong; Booth, Jeremy T; Thorwarth, Ryan; Moran, Jean M

2015-10-01

The purpose of this study was 2-fold. One purpose was to develop an automated, streamlined quality assurance (QA) program for use by multiple centers. The second purpose was to evaluate machine performance over time for multiple centers using linear accelerator (Linac) log files and electronic portal images. The authors sought to evaluate variations in Linac performance to establish as a reference for other centers. The authors developed analytical software tools for a QA program using both log files and electronic portal imaging device (EPID) measurements. The first tool is a general analysis tool which can read and visually represent data in the log file. This tool, which can be used to automatically analyze patient treatment or QA log files, examines the files for Linac deviations which exceed thresholds. The second set of tools consists of a test suite of QA fields, a standard phantom, and software to collect information from the log files on deviations from the expected values. The test suite was designed to focus on the mechanical tests of the Linac to include jaw, MLC, and collimator positions during static, IMRT, and volumetric modulated arc therapy delivery. A consortium of eight institutions delivered the test suite at monthly or weekly intervals on each Linac using a standard phantom. The behavior of various components was analyzed for eight TrueBeam Linacs. For the EPID and trajectory log file analysis, all observed deviations which exceeded established thresholds for Linac behavior resulted in a beam hold off. In the absence of an interlock-triggering event, the maximum observed log file deviations between the expected and actual component positions (such as MLC leaves) varied from less than 1% to 26% of published tolerance thresholds. The maximum and standard deviations of the variations due to gantry sag, collimator angle, jaw position, and MLC positions are presented. Gantry sag among Linacs was 0.336 ± 0.072 mm. The standard deviation in MLC position, as determined by EPID measurements, across the consortium was 0.33 mm for IMRT fields. With respect to the log files, the deviations between expected and actual positions for parameters were small (<0.12 mm) for all Linacs. Considering both log files and EPID measurements, all parameters were well within published tolerance values. Variations in collimator angle, MLC position, and gantry sag were also evaluated for all Linacs. The performance of the TrueBeam Linac model was shown to be consistent based on automated analysis of trajectory log files and EPID images acquired during delivery of a standardized test suite. The results can be compared directly to tolerance thresholds. In addition, sharing of results from standard tests across institutions can facilitate the identification of QA process and Linac changes. These reference values are presented along with the standard deviation for common tests so that the test suite can be used by other centers to evaluate their Linac performance against those in this consortium.

The Tennessee Mouse Genome Consortium: Identification of ocular mutants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jablonski, Monica M.; Wang, Xiaofei; Lu, Lu

2005-06-01

The Tennessee Mouse Genome Consortium (TMGC) is in its fifth year of a ethylnitrosourea (ENU)-based mutagenesis screen to detect recessive mutations that affect the eye and brain. Each pedigree is tested by various phenotyping domains including the eye, neurohistology, behavior, aging, ethanol, drug, social behavior, auditory, and epilepsy domains. The utilization of a highly efficient breeding protocol and coordination of various universities across Tennessee makes it possible for mice with ENU-induced mutations to be evaluated by nine distinct phenotyping domains within this large-scale project known as the TMGC. Our goal is to create mutant lines that model human diseases andmore » disease syndromes and to make the mutant mice available to the scientific research community. Within the eye domain, mice are screened for anterior and posterior segment abnormalities using slit-lamp biomicroscopy, indirect ophthalmoscopy, fundus photography, eye weight, histology, and immunohistochemistry. As of January 2005, we have screened 958 pedigrees and 4800 mice, excluding those used in mapping studies. We have thus far identified seven pedigrees with primary ocular abnormalities. Six of the mutant pedigrees have retinal or subretinal aberrations, while the remaining pedigree presents with an abnormal eye size. Continued characterization of these mutant mice should in most cases lead to the identification of the mutated gene, as well as provide insight into the function of each gene. Mice from each of these pedigrees of mutant mice are available for distribution to researchers for independent study.« less

Biodegradation of commercial gasoline (24% ethanol added) in liquid medium by microorganisms isolated from a landfarming site.

PubMed

Oliveira, Núbia M; Bento, Fátima M; Camargo, Flávio A O; Knorst, Aline Jéssica; Dos Santos, Anai Loreiro; Pizzolato, Tania M; Peralba, Maria do Carmo R

2011-01-01

Isolation of soil microorganisms from a landfarming site with a 19-year history of petrochemical residues disposal was carried out. After isolation, the bacteria behavior in mineral medium with 1% commercial gasoline (24% ethanol) was evaluated. Parameters employed for microorganism evaluation and selection of those with the greatest degradation potential were: microbial growth; biosurfactant generation and compound reduction in commercial gasoline. Starting from bacteria that presented the best degradation results, consortiums formed by 4 distinct microorganisms were formed. A microbial growth in the presence of commercial gasoline was observed and, for most of the bacteria, degradations of compounds such as benzene, toluene and xylenes (BTX) as well as biosurfactant production was observed. Ethanol was partially degraded by the bacterial isolates although the data does not allow affirming that it was degraded preferentially to the aromatic hydrocarbons investigated. The analyzed consortiums present an efficiency of 95% to 98% for most of the commercial gasoline compounds and a preferential attack to ethanol under the essay condition was not observed within 72 h.

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2010 CFR

2010-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

24 CFR 943.128 - How does a consortium carry out planning and reporting functions?

Code of Federal Regulations, 2010 CFR

2010-04-01

... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING AGENCY CONSORTIA AND JOINT VENTURES... the consortium agreement, the consortium must submit joint five-year Plans and joint Annual Plans for... the joint PHA Plan. ...

THE FEDERAL INTEGRATED BIOTREATMENT RESEARCH CONSORTIUM (FLASK TO FIELD)

EPA Science Inventory

The Federal Integrated Biotreatment Research Consortium (Flask to Field) represented a 7-year concerted effort by several research laboratories to develop bioremediation technologies for contaminated DoD sites. The consortium structure consisted of a director and four thrust are...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2013 CFR

2013-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2012 CFR

2012-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2011 CFR

2011-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2014 CFR

2014-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

Implementing the Indiana Model. Indiana Leadership Consortium: Equity through Change.

ERIC Educational Resources Information Center

Indiana Leadership Consortium.

This guide, which was developed as a part of a multi-year, statewide effort to institutionalize gender equity in various educational settings throughout Indiana, presents a step-by-step process model for achieving gender equity in the state's secondary- and postsecondary-level vocational programs through coalition building and implementation of a…

Implementing a Military Transitions Program. Strategies for Transformative Change

ERIC Educational Resources Information Center

Mikulka, D.; Remy, K.; Smith, C.; Fox, H. L.

2016-01-01

In 2011, Washburn University of Topeka, Kansas was awarded a $19.6 million Round 1 TAACCCT grant through the Department of Labor to provide industry-relevant, hands-on training for high-demand, high-wage careers. The consortium, Technical Retraining to Achieve Credentials (TRAC-7), was led by Washburn University, and included seven Kansas…

An Examination of Specialized Schools as Agents of Educational Change.

ERIC Educational Resources Information Center

Hanford, Seth

One suggestion for educational improvement is the implementation of specialized schools that offer specific training with a focus. New York and a number of other cities have turned to this choice to offer specialized schools of mathematics and technology. The movement is coordinated on a national level by the National Consortium of Specialized…

Upskilling the Aerospace Workforce in Washington. Scaling Change: Air Washington Consortium

ERIC Educational Resources Information Center

Bragg, D. D.

2016-01-01

Several federal grants prioritized the role of community colleges in education and training in recent years, and one of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (DOL). Beginning October 2011, these $2 billion capacity-building…

Expanding Student Support Services. Scaling Change: MoHealthWINs Consortium

ERIC Educational Resources Information Center

Kirby, C. L.

2016-01-01

Several federal grants prioritized the role of community colleges in education and training in recent years, and one of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (DOL). Beginning October 2011, these $2 billion capacity-building…

The Emergence of Private Higher Education in Australia: The "Silent" Provider

ERIC Educational Resources Information Center

Bennett, Lorraine; Nair, Chenicheri Sid; Shah, Mahsood

2012-01-01

For many years, the university sector has been the dominant provider of higher education in Australia. However, recent changes in government policy which have broadened access to publicly-funded subsidised student loans have resulted in the emergence of small and large private higher education providers and consortiums offering English language,…

Early Detection Research Network (EDRN) | Division of Cancer Prevention

Cancer.gov

http://edrn.nci.nih.gov/EDRN is a collaborative network that maintains comprehensive infrastructure and resources critical to the discovery, development and validation of biomarkers for cancer risk and early detection. The program comprises a public/private sector consortium to accelerate the development of biomarkers that will change medical practice, ensure data

Putting the Pieces Together: Leadership for Change in Low-Performing Urban Schools

ERIC Educational Resources Information Center

Orr, Margaret Terry; Berg, Barbara; Shore, Rima; Meier, Ellen

2008-01-01

This article presents a collaborative inquiry analysis of the school improvement experiences of four persistently low-performing schools. It draws on the experiences of three members of the Laboratory for the Design and Redesign of Schools (LDRS) consortium who helped during their planning for restructuring or restructuring phases and one regional…

Creating Resiliency and Pathways to Opportunity. Strategies for Transformative Change

ERIC Educational Resources Information Center

Powell, M.; Hatch, M. A.; Fians, E.; Shinert, A.; Richie, D.

2016-01-01

Like many colleges funded by the U.S. Department of Labor's TAACCCT program, the goal of the Northeast Resiliency Consortium (NRC) (a Round Three grantee) was to enhance the capacity of colleges to accelerate learning, ensure that students attain industry-recognized credentials, foster innovative employer partnerships, use new technologies, and…

Changing Residential Child Care: A Systems Approach to Consultation Training and Development

ERIC Educational Resources Information Center

Gibson, Johnnie; Leonard, Marcella; Wilson, Mena

2004-01-01

In this article, the authors describe and illustrate their approach to consultancy, development and training in residential child care. When working together the authors form the MOSAIC Consortium and provide training and consultancy to residential child care services. The article draws on systems theory, systems thinking and the politics of child…

Building a Foundational Model for Credit for Prior Learning. Strategies for Transformative Change

ERIC Educational Resources Information Center

Kamps, A.; Loritz, T.; Schaff, E.; Richie, D.

2016-01-01

"Making the Future: The Wisconsin Strategy," under the leadership of Northeast Wisconsin Technical College (NWTC), received a Round Two U.S. Department of Labor Trade Adjustment Assistance for Community College and Career Training (TAACCCT) grant. The consortium brought together all 16 colleges in the Wisconsin Technical College System…

Breaking out of the Box: New Colleges for a New Century. 1996 Critical Issues Paper.

ERIC Educational Resources Information Center

Carter, Patricia; Alfred, Richard

In this book, the Consortium for Community College Development's Think Tank (Michigan) identifies four critical and enduring issues for change in community colleges: (1) attracting and recruiting students in an increasingly competitive market; (2) improving student success through innovative approaches to teaching and learning; (3) encouraging…

REPORT OF THE NIH TASK FORCE ON RESEARCH STANDARDS FOR CHRONIC LOW BACK PAIN

PubMed Central

Deyo, Richard A.; Dworkin, Samuel F.; Amtmann, Dagmar; Andersson, Gunnar; Borenstein, David; Carragee, Eugene; Carrino, John; Chou, Roger; Cook, Karon; DeLitto, Anthony; Goertz, Christine; Khalsa, Partap; Loeser, John; Mackey, Sean; Panagis, James; Rainville, James; Tosteson, Tor; Turk, Dennis; Von Korff, Michael; Weiner, Debra K.

2014-01-01

Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients’ lives. Such cLBP is often termed non-specific, and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. The NIH Pain Consortium therefore charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimal data set to describe research participants (drawing heavily on the PROMIS methodology); reporting “responder analyses” in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect the RTF recommendations will become a dynamic document, and undergo continual improvement. Perspective A Task Force was convened by the NIH Pain Consortium, with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimal dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes. PMID:24787228

Actinobacteria consortium as an efficient biotechnological tool for mixed polluted soil reclamation: Experimental factorial design for bioremediation process optimization.

PubMed

Aparicio, Juan Daniel; Raimondo, Enzo Emanuel; Gil, Raúl Andrés; Benimeli, Claudia Susana; Polti, Marta Alejandra

2018-01-15

The objective of the present work was to establish optimal biological and physicochemical parameters in order to remove simultaneously lindane and Cr(VI) at high and/or low pollutants concentrations from the soil by an actinobacteria consortium formed by Streptomyces sp. M7, MC1, A5, and Amycolatopsis tucumanensis AB0. Also, the final aim was to treat real soils contaminated with Cr(VI) and/or lindane from the Northwest of Argentina employing the optimal biological and physicochemical conditions. In this sense, after determining the optimal inoculum concentration (2gkg -1 ), an experimental design model with four factors (temperature, moisture, initial concentration of Cr(VI) and lindane) was employed for predicting the system behavior during bioremediation process. According to response optimizer, the optimal moisture level was 30% for all bioremediation processes. However, the optimal temperature was different for each situation: for low initial concentrations of both pollutants, the optimal temperature was 25°C; for low initial concentrations of Cr(VI) and high initial concentrations of lindane, the optimal temperature was 30°C; and for high initial concentrations of Cr(VI), the optimal temperature was 35°C. In order to confirm the model adequacy and the validity of the optimization procedure, experiments were performed in six real contaminated soils samples. The defined actinobacteria consortium reduced the contaminants concentrations in five of the six samples, by working at laboratory scale and employing the optimal conditions obtained through the factorial design. Copyright © 2017 Elsevier B.V. All rights reserved.

The Historically Black Colleges and Universities/Minority Institutions Environmental Technology Consortium annual report, 1991--1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1992-12-31

The member institutions of the Consortium continue to play a significant role in increasing the number of African Americans who enter the environmental professions through the implementation of the Consortium`s RETT Plan for Research, Education, and Technology Transfer. The four major program areas identified in the RETT Plan are as follows: (1) minority outreach and precollege education; (2) undergraduate education and postsecondary training; (3) graduate and postgraduate education and research; and (4) technology transfer.

25 CFR 1000.84 - Does a Tribe/Consortium have the right to include provisions of Title I of Pub. L. 93-638 in an AFA?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Does a Tribe/Consortium have the right to include.../Consortium have the right to include provisions of Title I of Pub. L. 93-638 in an AFA? Yes, under Pub. L. 104-109, a Tribe/Consortium has the right to include any provision of Title I of Pub. L. 93-638 in an...

Migrating from Informal to Formal Consortium — COSTLI Issues

NASA Astrophysics Data System (ADS)

Birdie, C.; Patil, Y. M.

2010-10-01

There are many models of library consortia which have come into existence due to various reasons and compulsions. FORSA (Forum for Resource Sharing in Astronomy) is an informal consortium born from the links between academic institutions specializing in astronomy in India. FORSA is a cooperative venture initiated by library professionals. Though this consortium was formed mainly for inter-lending activities and bibliographic access, it has matured over the years to adopt the consortium approach on cooperative acquisitions, due to increased requirements.

Identifying the Role of the International Consortium ``MIT/ LINC'' in Supporting the Integration of ICT in Higher Education in Emerging Countries

NASA Astrophysics Data System (ADS)

Park, Young; Moser, Franziska Zellweger

2008-04-01

The goal of this research effort is to provide insights on what core needs and difficulties exist toward the implementation of ICT in higher education in emerging countries and how a consortium like LINC can best support these efforts. An exploratory research design combining a survey, on-site interviews, participant observation and document analysis were employed to answer the research questions. Main challenges in establishing technology- based learning environments were identified in the area of pedagogies, finances, technological infrastructure, cultural change, organization, and management. LINC, as an non-political organization embedded in an academic environment, can take an important role in facilitating the dialogue among participants through various platforms, take an active role in promoting joint programs and assist with efforts to "localize" tools and practice.

Exploring the Association between Alzheimer's Disease, Oral Health, Microbial Endocrinology and Nutrition.

PubMed

Harding, Alice; Gonder, Ulrike; Robinson, Sarita J; Crean, StJohn; Singhrao, Sim K

2017-01-01

Longitudinal monitoring of patients suggests a causal link between chronic periodontitis and the development of Alzheimer's disease (AD). However, the explanation of how periodontitis can lead to dementia remains unclear. A working hypothesis links extrinsic inflammation as a secondary cause of AD. This hypothesis suggests a compromised oral hygiene leads to a dysbiotic oral microbiome whereby Porphyromonas gingivalis , a keystone periodontal pathogen, with its companion species, orchestrates immune subversion in the host. Brushing and chewing on teeth supported by already injured soft tissues leads to bacteremias. As a result, a persistent systemic inflammatory response develops to periodontal pathogens. The pathogens, and the host's inflammatory response, subsequently lead to the initiation and progression of multiple metabolic and inflammatory co-morbidities, including AD. Insufficient levels of essential micronutrients can lead to microbial dysbiosis through the growth of periodontal pathogens such as demonstrated for P. gingivalis under low hemin bioavailability. An individual's diet also defines the consortium of microbial communities that take up residency in the oral and gastrointestinal (GI) tract microbiomes. Their imbalance can lead to behavioral changes. For example, probiotics enriched in Lactobacillus genus of bacteria, when ingested, exert some anti-inflammatory influence through common host/bacterial neurochemicals, both locally, and through sensory signaling back to the brain. Early life dietary behaviors may cause an imbalance in the host/microbial endocrinology through a dietary intake incompatible with a healthy GI tract microbiome later in life. This imbalance in host/microbial endocrinology may have a lasting impact on mental health. This observation opens up an opportunity to explore the mechanisms, which may underlie the previously detected relationship between diet, oral/GI microbial communities, to anxiety, cognition and sleep patterns. This review suggests healthy diet based interventions that together with improved life style/behavioral changes may reduce and/or delay the incidence of AD.

Exploring the Association between Alzheimer’s Disease, Oral Health, Microbial Endocrinology and Nutrition

PubMed Central

Harding, Alice; Gonder, Ulrike; Robinson, Sarita J.; Crean, StJohn; Singhrao, Sim K.

2017-01-01

Longitudinal monitoring of patients suggests a causal link between chronic periodontitis and the development of Alzheimer’s disease (AD). However, the explanation of how periodontitis can lead to dementia remains unclear. A working hypothesis links extrinsic inflammation as a secondary cause of AD. This hypothesis suggests a compromised oral hygiene leads to a dysbiotic oral microbiome whereby Porphyromonas gingivalis, a keystone periodontal pathogen, with its companion species, orchestrates immune subversion in the host. Brushing and chewing on teeth supported by already injured soft tissues leads to bacteremias. As a result, a persistent systemic inflammatory response develops to periodontal pathogens. The pathogens, and the host’s inflammatory response, subsequently lead to the initiation and progression of multiple metabolic and inflammatory co-morbidities, including AD. Insufficient levels of essential micronutrients can lead to microbial dysbiosis through the growth of periodontal pathogens such as demonstrated for P. gingivalis under low hemin bioavailability. An individual’s diet also defines the consortium of microbial communities that take up residency in the oral and gastrointestinal (GI) tract microbiomes. Their imbalance can lead to behavioral changes. For example, probiotics enriched in Lactobacillus genus of bacteria, when ingested, exert some anti-inflammatory influence through common host/bacterial neurochemicals, both locally, and through sensory signaling back to the brain. Early life dietary behaviors may cause an imbalance in the host/microbial endocrinology through a dietary intake incompatible with a healthy GI tract microbiome later in life. This imbalance in host/microbial endocrinology may have a lasting impact on mental health. This observation opens up an opportunity to explore the mechanisms, which may underlie the previously detected relationship between diet, oral/GI microbial communities, to anxiety, cognition and sleep patterns. This review suggests healthy diet based interventions that together with improved life style/behavioral changes may reduce and/or delay the incidence of AD. PMID:29249963

Applying the COM-B model to creation of an IT-enabled health coaching and resource linkage program for low-income Latina moms with recent gestational diabetes: the STAR MAMA program.

PubMed

Handley, Margaret A; Harleman, Elizabeth; Gonzalez-Mendez, Enrique; Stotland, Naomi E; Althavale, Priyanka; Fisher, Lawrence; Martinez, Diana; Ko, Jocelyn; Sausjord, Isabel; Rios, Christina

2016-05-18

One of the fastest growing risk groups for early onset of diabetes is women with a recent pregnancy complicated by gestational diabetes, and for this group, Latinas are the largest at-risk group in the USA. Although evidence-based interventions, such as the Diabetes Prevention Program (DPP), which focuses on low-cost changes in eating, physical activity and weight management can lower diabetes risk and delay onset, these programs have yet to be tailored to postpartum Latina women. This study aims to tailor a IT-enabled health communication program to promote DPP-concordant behavior change among postpartum Latina women with recent gestational diabetes. The COM-B model (incorporating Capability, Opportunity, and Motivational behavioral barriers and enablers) and the Behavior Change Wheel (BCW) framework, convey a theoretically based approach for intervention development. We combined a health literacy-tailored health IT tool for reaching ethnic minority patients with diabetes with a BCW-based approach to develop a health coaching intervention targeted to postpartum Latina women with recent gestational diabetes. Current evidence, four focus groups (n = 22 participants), and input from a Regional Consortium of health care providers, diabetes experts, and health literacy practitioners informed the intervention development. Thematic analysis of focus group data used the COM-B model to determine content. Relevant cultural, theoretical, and technological components that underpin the design and development of the intervention were selected using the BCW framework. STAR MAMA delivers DPP content in Spanish and English using health communication strategies to: (1) validate the emotions and experiences postpartum women struggle with; (2) encourage integration of prevention strategies into family life through mothers becoming intergenerational custodians of health; and (3) increase social and material supports through referral to social networks, health coaches, and community resources. Feasibility, acceptability, and health-related outcomes (weight loss, physical activity, consumption of healthy foods, breastfeeding, and glucose screening) will be evaluated at 9 months postpartum using a randomized controlled trial design. STAR MAMA provides a DPP-based intervention that integrates theory-based design steps. Through systematic use of behavioral theory to inform intervention development, STAR MAMA may represent a strategy to develop health IT intervention tools to meet the needs of diverse populations. ClinicalTrials.gov NCT02240420.

Increasing Sales by Developing Production Consortiums.

ERIC Educational Resources Information Center

Smith, Christopher A.; Russo, Robert

Intended to help rehabilitation facility administrators increase organizational income from manufacturing and/or contracted service sources, this document provides a decision-making model for the development of a production consortium. The document consists of five chapters and two appendices. Chapter 1 defines the consortium concept, explains…

14 CFR 1274.205 - Consortia as recipients.

Code of Federal Regulations, 2010 CFR

2010-01-01

... agreement with a consortium is the consortium's Articles of Collaboration, which is a definitive description of the roles and responsibilities of the consortium's members. The Articles of Collaboration must... the Articles of Collaboration only if they are inclusive of all of the required information. (e) An...

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2010 CFR

2010-01-01

... is not formally incorporated must provide a collaboration agreement, commonly referred to as the articles of collaboration, which sets out the rights and responsibilities of each consortium member. This... the consortium's collaboration agreement to ensure that the management plan is sound and that it...

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2011 CFR

2011-01-01

... is not formally incorporated must provide a collaboration agreement, commonly referred to as the articles of collaboration, which sets out the rights and responsibilities of each consortium member. This... the consortium's collaboration agreement to ensure that the management plan is sound and that it...

14 CFR 1274.205 - Consortia as recipients.

Code of Federal Regulations, 2011 CFR

2011-01-01

... agreement with a consortium is the consortium's Articles of Collaboration, which is a definitive description of the roles and responsibilities of the consortium's members. The Articles of Collaboration must... the Articles of Collaboration only if they are inclusive of all of the required information. (e) An...

25 CFR 1000.21 - When does a Tribe/Consortium have a “material audit exception”?

Code of Federal Regulations, 2010 CFR

2010-04-01

...-Governance Eligibility § 1000.21 When does a Tribe/Consortium have a “material audit exception”? A Tribe/Consortium has a material audit exception if any of the audits that it submitted under § 1000.17(c...

Consortium List of African-American Materials.

ERIC Educational Resources Information Center

Jordan, Casper L., Ed.

A bibliography is provided of the materials identified by the consortium participating in the African-American Materials Project. Members of the consortium include: Atlanta University, Fisk University, Hampton Institute, North Carolina Central University, South Carolina State College, and Tuskegee Institute. The materials listed were located in…

76 FR 66040 - Announcement of Meeting To Explore Feasibility of Establishing a NIST/Industry Consortium on...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-25

... Explore Feasibility of Establishing a NIST/Industry Consortium on ``Concrete Rheology: Enabling Metrology... meeting. SUMMARY: The National Institute of Standards and Technology (NIST) invites interested parties to attend a pre-consortium meeting on November 8, [[Page 66041

Recovery of valuable metals from polymetallic mine tailings by natural microbial consortium.

PubMed

Vardanyan, Narine; Sevoyan, Garegin; Navasardyan, Taron; Vardanyan, Arevik

2018-05-28

Possibilities for the recovery of non-ferrous and precious metals from Kapan polymetallic mine tailings (Armenia) were studied. The aim of this paper was to study the possibilities of bioleaching of samples of concentrated tailings by the natural microbial consortium of drainage water. The extent of extraction of metals from the samples of concentrated tailings by natural microbial consortium reached 41-55% and 53-73% for copper and zinc, respectively. Metal leaching efficiencies of pure culture Leptospirillum ferrooxidans Teg were higher, namely 47-93% and 73-81% for copper and zinc, respectively. The content of gold in solid phase of tailings increased about 7-16% and 2-9% after bio-oxidation process by L. ferrooxidans Teg and natural microbial consortium, respectively. It was shown that bioleaching of the samples of tailings could be performed using the natural consortium of drainage water. However, to increase the intensity of the recovery of valuable metals, natural consortium of drainage water combined with iron-oxidizing L. ferrooxidans Teg has been proposed.

Pretreatment of piggery wastewater by a stable constructed microbial consortium for improving the methane production.

PubMed

Cai, Jian; Mo, Xiwei; Cheng, Guojun; Du, Dongyun

2015-01-01

A stable aerobic microbial consortium, established by successive subcultivation, was employed to solubilize the solid organic fraction in swine wastewater. In the 30 days' successive biological pretreatments, 30-38% of volatile solids and 19-28% total solids in raw slurry were solubilized after 10 hours at 37 °C. Meanwhile, soluble chemical oxygen demand (COD) and volatile fatty acid increased by 48%-56% and 600%-750%, respectively. Furthermore, the molecular microbial profile of the consortium in successive pretreatment was conducted by denaturing gradient gel electrophoresis (DGGE). The results indicated that bacterial species of the consortium rapidly overgrew the indigenous microbial community of raw water, and showed a stable predominance at the long-term treatment. As a consequence of biological pretreatment, pretreatment shortened digestion time by 50% and increased biogas production by 45% compared to raw water in the anaerobic process. The microbial consortium constructed herein is a potential candidate consortium for biological pretreatment of swine wastewater to enhance biogas production.

[Activity of NTDs Drug-discovery Research Consortium].

PubMed

Namatame, Ichiji

2016-01-01

Neglected tropical diseases (NTDs) are an extremely important issue facing global health care. To improve "access to health" where people are unable to access adequate medical care due to poverty and weak healthcare systems, we have established two consortiums: the NTD drug discovery research consortium, and the pediatric praziquantel consortium. The NTD drug discovery research consortium, which involves six institutions from industry, government, and academia, as well as an international non-profit organization, is committed to developing anti-protozoan active compounds for three NTDs (Leishmaniasis, Chagas disease, and African sleeping sickness). Each participating institute will contribute their efforts to accomplish the following: selection of drug targets based on information technology, and drug discovery by three different approaches (in silico drug discovery, "fragment evolution" which is a unique drug designing method of Astellas Pharma, and phenotypic screening with Astellas' compound library). The consortium has established a brand new database (Integrated Neglected Tropical Disease Database; iNTRODB), and has selected target proteins for the in silico and fragment evolution drug discovery approaches. Thus far, we have identified a number of promising compounds that inhibit the target protein, and we are currently trying to improve the anti-protozoan activity of these compounds. The pediatric praziquantel consortium was founded in July 2012 to develop and register a new praziquantel pediatric formulation for the treatment of schistosomiasis. Astellas Pharma has been a core member in this consortium since its establishment, and has provided expertise and technology in the area of pediatric formulation development and clinical development.

Bacterial community dynamic associated with autochthonous bioaugmentation for enhanced Cu phytoremediation of salt-marsh sediments.

PubMed

Almeida, C Marisa R; Oliveira, Tânia; Reis, Izabela; Gomes, Carlos R; Mucha, Ana P

2017-12-01

Autochthonous bioaugmentation for metal phytoremediation is still little explored, particularly its application to estuarine salt marshes, but results obtained so far are promising. Nevertheless, understanding the behaviour of the microbial communities in the process of bioaugmentation and their role in improving metal phytoremediation is very important to fully validate the application of this biological technology. This study aimed to characterize the bacterial community dynamic associated with the application of autochthonous bioaugmentation in an experimentation which showed that Phragmites australis rhizosphere microorganisms could increase this salt marsh plant potential to phytoremediate Cu contaminated sediments. Bacterial communities present in the autochthonous microbial consortium resistant to Cu added to the medium and in the sediment at the beginning and at the end of the experiment were characterized by ARISA. Complementarily, the consortium and the sediment used for its production were characterized by next generation sequencing using the pyrosequencing platform 454. The microbial consortium resistant to Cu obtained from non-vegetated sediment was dominated by the genus Lactococcus (46%), Raoultella (25%), Bacillus (12%) and Acinetobacter (11%), whereas the one obtained form rhizosediment was dominated by the genus Gluconacetobacter (77%), Bacillus (17%) and Dyella (3%). Results clearly showed that, after two months of experiment, Cu caused a shift in the bacterial community structure of sediments, an effect that was observed either with or without addition of the metal resistant microbial consortium. Therefore, bioaugmentation application improved the process of phytoremediation (metal translocation by the plant was increased) without inducing long term changes in the bacterial community structure of the sediments. So, phytoremediation combined with autochthonous bioaugmentation can be a suitable technology for the recovery of estuarine areas, contributing for an efficient risk management strategy of these coastal zones. Copyright © 2017. Published by Elsevier Ltd.

40 CFR 35.6010 - Indian Tribe and intertribal consortium eligibility.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Indian Tribe and intertribal consortium... for Superfund Response Actions General § 35.6010 Indian Tribe and intertribal consortium eligibility. (a) Indian Tribes are eligible to receive Superfund Cooperative Agreements only when they are...

40 CFR 35.6010 - Indian Tribe and intertribal consortium eligibility.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Indian Tribe and intertribal consortium... for Superfund Response Actions General § 35.6010 Indian Tribe and intertribal consortium eligibility. (a) Indian Tribes are eligible to receive Superfund Cooperative Agreements only when they are...

40 CFR 35.6010 - Indian Tribe and intertribal consortium eligibility.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Indian Tribe and intertribal consortium... for Superfund Response Actions General § 35.6010 Indian Tribe and intertribal consortium eligibility. (a) Indian Tribes are eligible to receive Superfund Cooperative Agreements only when they are...

40 CFR 35.6010 - Indian Tribe and intertribal consortium eligibility.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Indian Tribe and intertribal consortium... for Superfund Response Actions General § 35.6010 Indian Tribe and intertribal consortium eligibility. (a) Indian Tribes are eligible to receive Superfund Cooperative Agreements only when they are...

Limiter heat loads during the first operation of the W7-X stellarator

NASA Astrophysics Data System (ADS)

Wurden, Glen; Niemann, Holger; Jakubowski, Marcin; Bozhenkov, Sergey; Biedermann, Christoph; Marsen, Stefan; Effenberg, Florian; Stephey, Laurie; Schmitz, Oliver; W7-X Team

2016-10-01

During the first operational phase (OP1.1) of the new W7-X stellarator, five poloidal graphite limiters served as the main boundary for the plasma. There was a dedicated set of diagnostics to observe the performance of the temporary poloidal limiters and infer basic transport behavior of the 3-D helical SOL plasma. We describe IR imaging of the limiters, which resulted in observations of 1) heat flux determination as a function of time and space, 2) total energy into the limiters, 3) high-frequency helical patterns of energy bursts onto the limiters, 4) changes in surface emissivity, and 5) detection of UFO's (small-to-large dusts). These measurements were made in 2 magnetic configuration discharges (differing iota), and in ones where the power loads to the limiters were systematically modified by the use of trim coils. Observed power fractions on the limiters ranged from 40% to 20% of the 0.6 to 4 MW ECRH input powers. Acknowledgement: Funded under DOE LANS Contract DE-AC5026NA25396 and DE-SC0014210, and within the EUROfusion Consortium under Euratom Grant 633053.

15 CFR 918.5 - Eligibility, qualifications, and responsibilities-Sea Grant Regional Consortia.

Code of Federal Regulations, 2010 CFR

2010-01-01

... qualifying areas which are pertinent to the Consortium's program: (1) Leadership. The Sea Grant Regional... Consortium candidate must have created the management organization to carry on a viable and productive... assistance as the consortium may offer, and (iii) to assist others in developing research and management...

International Arid Lands Consortium: A synopsis of accomplishments

Treesearch

Peter F. Ffolliott; Jeffrey O. Dawson; James T. Fisher; Itshack Moshe; Timothy E. Fulbright; W. Carter Johnson; Paul Verburg; Muhammad Shatanawi; Jim P. M. Chamie

2003-01-01

The International Arid Lands Consortium (IALC) was established in 1990 to promote research, education, and training activities related to the development, management, and reclamation of arid and semiarid lands in the Southwestern United States, the Middle East, and elsewhere in the world. The Consortium supports the ecological sustainability and environmentally sound...

32 CFR 37.515 - Must I do anything additional to determine the qualification of a consortium?

Code of Federal Regulations, 2010 CFR

2010-07-01

... SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business... relationship is essential to increase the research project's chances of success. (b) The collaboration... things, the consortium's: (1) Management structure. (2) Method of making payments to consortium members...

Consortia: A Challenge to Institutional Autonomy.

ERIC Educational Resources Information Center

Wood, Herbert H.

The kinds of impact a consortium might have on the operations of its member institutions are presented following an overview of the consortium's challenge to institutional autonomy. Ten attitudinal forms of consortium impact challenging autonomy include: (1) the rest are going ahead so do it anyway, (2) infiltration and multiple loyalities of…

The Neuroscience Peer Review Consortium

PubMed Central

Saper, Clifford B; Maunsell, John HR

2009-01-01

As the Neuroscience Peer Review Consortium (NPRC) ends its first year, it is worth looking back to see how the experiment has worked. In order to encourage dissemination of the details outlined in this Editorial, it will also be published in other journals in the Neuroscience Peer Review Consortium. PMID:19284614

Policy Report of the Physician Consortium on Substance Abuse Education.

ERIC Educational Resources Information Center

Lewis, David C.; Faggett, Walter L.

This report contains the recommendations of the Physician Consortium for significantly improving medical education and training to enhance the physician's role in early identification, treatment, and prevention of substance abuse. In addition, the consortium subcommittees report on their examination of substance abuse treatment needs of ethnic and…

77 FR 38770 - Notice of Consortium on “nSoft Consortium”

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-29

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Notice of Consortium on ``n...: NIST will form the ``nSoft Consortium'' to advance and transfer neutron based measurement methods for soft materials manufacturing. The goals of nSoft are to develop neutron- based measurements that...

78 FR 47674 - Genome in a Bottle Consortium-Progress and Planning Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-06

... quantitative performance metrics for confidence in variant calling. These standards and quantitative..., reproducible research and regulated applications in the clinic. On April 13, 2012, NIST convened the workshop... consortium. No proprietary information will be shared as part of the consortium, and all research results...

Targets of Opportunity: Strategies for Managing a Staff Development Consortium.

ERIC Educational Resources Information Center

Parsons, Michael H.

The Appalachian Staff Development Consortium, comprised of three community colleges and the state college located in Appalachian Maryland, attempts to integrate staff development activities into the operational framework of the sponsoring agencies. The consortium, which is managed by a steering committee composed of one teaching faculty member and…

Cohort Profile: The International Childhood Cardiovascular Cohort (i3C) Consortium

PubMed Central

Dwyer, Terence; Sun, Cong; Magnussen, Costan G; Raitakari, Olli T; Schork, Nicholas J; Venn, Alison; Burns, Trudy L; Juonala, Markus; Steinberger, Julia; Sinaiko, Alan R; Prineas, Ronald J; Davis, Patricia H; Woo, Jessica G; Morrison, John A; Daniels, Stephen R; Chen, Wei; Srinivasan, Sathanur R; Viikari, Jorma SA; Berenson, Gerald S

2013-01-01

This is a consortium of large children's cohorts that contain measurements of major cardiovascular disease (CVD) risk factors in childhood and had the ability to follow those cohorts into adulthood. The purpose of this consortium is to enable the pooling of data to increase power, most importantly for the follow-up of CVD events in adulthood. Within the consortium, we hope to be able to obtain data on the independent effects of childhood and early adult levels of CVD risk factors on subsequent CVD occurrence. PMID:22434861

Could petroleum biodegradation be a joint achievement of aerobic and anaerobic microrganisms in deep sea reservoirs?

PubMed Central

2011-01-01

Several studies suggest that petroleum biodegradation can be achieved by either aerobic or anaerobic microorganisms, depending on oxygen input or other electron acceptors and appropriate nutrients. Evidence from in vitro experiments with samples of petroleum formation water and oils from Pampo Field indicate that petroleum biodegradation is more likely to be a joint achievement of both aerobic and anaerobic bacterial consortium, refining our previous observations of aerobic degradation. The aerobic consortium depleted, in decreasing order, hydrocarbons > hopanes > steranes > tricyclic terpanes while the anaerobic consortium depleted hydrocarbons > steranes > hopanes > tricyclic terpanes. The oxygen content of the mixed consortia was measured from time to time revealing alternating periods of microaerobicity (O2 ~0.8 mg.L-1) and of aerobicity (O2~6.0 mg.L-1). In this experiment, the petroleum biodegradation changed from time to time, alternating periods of biodegradation similar to the aerobic process and periods of biodegradation similar to the anaerobic process. The consortia showed preferences for metabolizing hydrocarbons > hopanes > steranes > tricyclic terpanes during a 90-day period, after which this trend changed and steranes were more biodegraded than hopanes. The analysis of aerobic oil degrading microbiota by the 16S rRNA gene clone library detected the presence of Bacillus, Brevibacterium, Mesorhizobium and Achromobacter, and the analysis of the anaerobic oil degrading microbiota using the same technique detected the presence of Bacillus and Acinetobacter (facultative strains). In the mixed consortia Stenotrophomonas, Brevibacterium, Bacillus, Rhizobium, Achromobacter and 5% uncultured bacteria were detected. This is certainly a new contribution to the study of reservoir biodegradation processes, combining two of the more important accepted hypotheses. PMID:22196374

Soil mesocosm studies on atrazine bioremediation.

PubMed

Sagarkar, Sneha; Nousiainen, Aura; Shaligram, Shraddha; Björklöf, Katarina; Lindström, Kristina; Jørgensen, Kirsten S; Kapley, Atya

2014-06-15

Accumulation of pesticides in the environment causes serious issues of contamination and toxicity. Bioremediation is an ecologically sound method to manage soil pollution, but the bottleneck here, is the successful scale-up of lab-scale experiments to field applications. This study demonstrates pilot-scale bioremediation in tropical soil using atrazine as model pollutant. Mimicking field conditions, three different bioremediation strategies for atrazine degradation were explored. 100 kg soil mesocosms were set-up, with or without atrazine application history. Natural attenuation and enhanced bioremediation were tested, where augmentation with an atrazine degrading consortium demonstrated best pollutant removal. 90% atrazine degradation was observed in six days in soil previously exposed to atrazine, while soil without history of atrazine use, needed 15 days to remove the same amount of amended atrazine. The bacterial consortium comprised of 3 novel bacterial strains with different genetic atrazine degrading potential. The progress of bioremediation was monitored by measuring the levels of atrazine and its intermediate, cyanuric acid. Genes from the atrazine degradation pathway, namely, atzA, atzB, atzD, trzN and trzD were quantified in all mesocosms for 60 days. The highest abundance of all target genes was observed on the 6th day of treatment. trzD was observed in the bioaugmented mesocosms only. The bacterial community profile in all mesocosms was monitored by LH-PCR over a period of two months. Results indicate that the communities changed rapidly after inoculation, but there was no drastic change in microbial community profile after 1 month. Results indicated that efficient bioremediation of atrazine using a microbial consortium could be successfully up-scaled to pilot scale. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Western North Carolina Technology Consortium: A Collaborative Approach to Bridging the Digital Divide

ERIC Educational Resources Information Center

Sink, David W.; Jackson, Karen Luke; Boham, Kenneth A.; Shockley, David

2004-01-01

Community college presidents face an uphill struggle in preparing their institutions for the rapidly changing technological learning environment. Visionary presidents in rural community colleges are presented with yet another challenge: that of finding themselves on the wrong side of the digital divide. This article describes how presidents of 12…

Notice of Changes to RFA-CA-15-022 and Pre-Application Webinar | Office of Cancer Clinical Proteomics Research

Cancer.gov

The National Cancer Institute will hold a public Pre-Application webinar on Wednesday, January 13, 2016 at 12:00 p.m. (EST) for the Funding Opportunity Announcement (FOA) RFA-CA-15-022 entitled “Proteogenomic Translational Research Centers for Clinical Proteomic Tumor Analysis Consortium (U01).”

Entrepreneurship and Economic Development: Catalysts for Change. Proceedings of the Meeting of the National Entrepreneurship Education Consortium (Las Vegas, Nevada, December 3, 1987).

ERIC Educational Resources Information Center

Ashmore, M. Catherine, Ed.

These proceedings include the following reports: "Entrepreneurship Education: The Seed of Economic Development" (Gordon Ropp); "A Community College Statewide System" (Randy Grissom); "REAL [Rural Education Action Learning] Enterprises" (June Atkinson); "SBIR [Small Business Innovation Research] Opportunities" (Lou Perry); "The Trade and…

77 FR 30999 - Notice of Submission for OMB Review; Office of Planning, Evaluation and Policy Development; Case...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-24

... Institutions of Higher Education that have entered into consortium arrangements with states or school districts... structure of the education they provide to current and prospective teachers of English Learners; (2) the nature of changes they attempt to make to the full teacher education program at their institutions; (3...

E-Learning Practices in North Cyprus Universities: Benefits, Drawbacks and Recommendations for Effective Implementation

ERIC Educational Resources Information Center

Hismanoglu, Murat

2011-01-01

The nature of higher education is changing in the world today. Rising tuition fees, reduced budgets, and an increasing need for distance education (New Media Consortium, 2007) are pushing educational institutions to reinvestigate how education is delivered. In line with this shifting context, e-learning is being practiced more and more frequently…

The Multilingual Reality of the Multinational Workplace: Language Policy and Language Use

ERIC Educational Resources Information Center

Angouri, Jo

2013-01-01

In the multinational corporation (MNC) context the crossing of linguistic boundaries and the fast-paced change of linguistic ecologies due to market trends and new business activities is the rule rather than the exception. Accordingly, the aim of this paper is to discuss language policy and language practice in one consortium of three…

Learning at Eco-Attractions: Exploring the Bifurcation of Nature and Culture through Experiential Environmental Education

ERIC Educational Resources Information Center

Dunkley, Ria Ann

2016-01-01

This article explores informal environmental education (EE) experiences at eco-attractions. A consortium of three UK-based environmental charities designed an eco-attraction-based EE program aiming to inspire responses to environmental change. Over six months, educators at six eco-attractions delivered this two-day program to 430 young people.…

Shrublands under fire: Disturbance and recovery in a changing world

Treesearch

Stanley G. Kitchen

2008-01-01

These proceedings are part of a series corresponding to fourteen symposia sponsored by the Shrub Research Consortium and published by the U.S. Forest Service, Intermountain Research Station (1983?1996) and Rocky Mountain Research Station (1999 to present). Themes for each symposium were selected to focus on various aspects of the biology, ecology, and management of...

The"minimum information about an environmental sequence" (MIENS) specification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yilmaz, P.; Kottmann, R.; Field, D.

We present the Genomic Standards Consortium's (GSC) 'Minimum Information about an ENvironmental Sequence' (MIENS) standard for describing marker genes. Adoption of MIENS will enhance our ability to analyze natural genetic diversity across the Tree of Life as it is currently being documented by massive DNA sequencing efforts from myriad ecosystems in our ever-changing biosphere.

Transforming College Practices and Student Experiences to Advance STEM Education. Scaling Change: National STEM Consortium

ERIC Educational Resources Information Center

Richie, D.

2016-01-01

Several federal grants prioritized the role of community colleges in education and training in recent years, and one of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (DOL). Beginning October 2011, these $2 billion capacity-building…

Improving Your Organisation's Workplace Learning. Consortium Research Program

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2008

2008-01-01

Many organisations, including VET providers, are looking to find ways to achieve competitive advantage through the people they employ. Creating this advantage has a number of facets and most of these depend on training and developing people, and their ability to learn. The VET sector also faces significant changes in the ways it does business.…

Impact of Calculus Reform in a Liberal Arts Calculus Course.

ERIC Educational Resources Information Center

Brosnan, Patricia A.; Ralley, Thomas G.

This report describes the changes in a freshman-level calculus course that occurred as a consequence of adopting the Harvard Consortium Calculus text. The perspective is that of the lecturer. The course is intended as an introduction to calculus for liberal arts students, that is, students who will not be expected to use calculus as a mathematical…

Changing the English Classroom: When Large-Scale "Common" Testing Meets Secondary Curriculum and Instruction in the United States

ERIC Educational Resources Information Center

Cimbricz, Sandra K.; McConn, Matthew L.

2015-01-01

This article explores the intersection of new, large-scale standards-based testing, teacher accountability policy, and secondary curriculum and instruction in the United States. Two federally funded consortia--the Smarter Balanced Assessment Consortium and the Partnership for Readiness of College and Careers--prove focal to this paper, as these…

Connection and Commitment: The Career of Carrie Billy

ERIC Educational Resources Information Center

Peterson, Richard

2015-01-01

Carrie Billy, a member of the Navajo Nation and CEO and president of the American Indian Higher Education Consortium (AIHEC), attributes one of the country's oldest youth organizations, Girl Scouts, for opening her mind to the possibility of creating change for countless citizens. She is a trained attorney and has made it her life work to advocate…

Anti-Sweatshop Groups Find It Difficult To Turn Campus Idealism into Real Change.

ERIC Educational Resources Information Center

Van der Werf, Martin

2001-01-01

Describes some of the efforts colleges have undertaken to ensure that clothing with college logos is not produced in sweatshops. Outlines work by the Fair Labor Association and the Workers Rights Consortium, organizations to which many colleges belong, to set up programs to monitor factories in the United States and other countries. (SLD)

Massachusetts Institute of Technology Consortium Agreement. Phase II

DTIC Science & Technology

1999-03-01

Portable VOR Testing Apparatusthe visual target. Head movements are monitored with magneto-hydrodynamic rotational velocity sensors , and eye motions are...Zhang 4. Miniaturization of the Ring Sensor B-H Yang, H. Asada, K-W. Chang , S. Rhee, Y. Zhang 5. SIMSUIT and Biochair Projects L. Jones, J. Tangorra...No change along 0 a•0a = (2) Neglect Vr = Vr = 0 (Wall velocity of r direction is very small compared with v.’.) a ax ax= (3) As r << x, Dr• >> axx

The Border Health Consortium of the Californias—Forming a Binational (California–Baja California) Entity to Address the Health of a Border Region: A Case Study

PubMed Central

Kozo, Justine; Zapata-Garibay, Rogelio; Rangel-Gomez, María Gudelia; Fernandez, April; Hirata-Okamoto, Ricardo; Wooten, Wilma; Vargas-Ojeda, Adriana; Jiménez, Barbara; Zepeda-Cisneros, Hector; Matthews, Charles Edwards

2018-01-01

The California–Baja California border region is one of the most frequently traversed areas in the world with a shared population, environment, and health concerns. The Border Health Consortium of the Californias (the “Consortium”) was formed in 2013 to bring together leadership working in the areas of public health, health care, academia, government, and the non-profit sector, with the goal of aligning efforts to improve health outcomes in the region. The Consortium utilizes a Collective Impact framework which supports a shared vision for a healthy border region, mutually reinforcing activities among member organizations and work groups, and a binational executive committee that ensures continuous communication and progress toward meeting its goals. The Consortium is comprised of four binational work groups which address human immunodeficiency virus, tuberculosis, obesity, and mental health, all mutual priorities in the border region. The Consortium holds two general binational meetings each year alternating between California and Baja California. The work groups meet regularly to share information, resources and provide binational training opportunities. Since inception, the Consortium has been successful in strengthening binational communication, coordination, and collaboration by providing an opportunity for individuals to meet one another, learn about each other systems, and foster meaningful relationships. With binational leadership support and commitment, the Consortium could certainly be replicated in other border jurisdictions both nationally and internationally. The present article describes the background, methodology, accomplishments, challenges, and lessons learned in forming the Consortium. PMID:29404318

A Report on the Oregon Consortium for Student Success.

ERIC Educational Resources Information Center

Keyser, John S.; And Others

This report provides an overview of the activities and outcomes of the Oregon Consortium for Student Success during 1980-81. As introductory material notes, the 13 community colleges involved in the consortium were charged with organizing a task force to improve advising and retention strategies for high risk students. The report emphasizes…

The West Virginia Consortium for Faculty and Course Development in International Studies.

ERIC Educational Resources Information Center

Peterson, Sophia; Maxwell, John

The West Virginia Consortium for Faculty and Course Development in International Studies (FACDIS) is described in this report. FACDIS, a consortium of 21 West Virginia institutions of higher education, assists in international studies course development, revision, and enrichment. It also helps faculty remain current in their fields and in new…

The Columbia-Willamette Skill Builders Consortium. Final Performance Report.

ERIC Educational Resources Information Center

Portland Community Coll., OR.

The Columbia-Willamette Skill Builders Consortium was formed in early 1988 in response to a growing awareness of the need for improved workplace literacy training and coordinated service delivery in Northwest Oregon. In June 1990, the consortium received a National Workplace Literacy Program grant to develop and demonstrate such training. The…

24 CFR 943.118 - What is a consortium?

Code of Federal Regulations, 2010 CFR

2010-04-01

... DEVELOPMENT PUBLIC HOUSING AGENCY CONSORTIA AND JOINT VENTURES Consortia § 943.118 What is a consortium? A... consortium also submits a joint PHA Plan. The lead agency collects the assistance funds from HUD that would... same fiscal year so that the applicable periods for submission and review of the joint PHA Plan are the...

15 CFR 918.6 - Duration of Sea Grant Regional Consortium designation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Duration of Sea Grant Regional... REGULATIONS SEA GRANTS § 918.6 Duration of Sea Grant Regional Consortium designation. Designation will be made... consistent with the goals of the Act. Continuation of the Sea Grant Regional Consortium designation is...

15 CFR 918.6 - Duration of Sea Grant Regional Consortium designation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Duration of Sea Grant Regional... REGULATIONS SEA GRANTS § 918.6 Duration of Sea Grant Regional Consortium designation. Designation will be made... consistent with the goals of the Act. Continuation of the Sea Grant Regional Consortium designation is...

15 CFR 918.6 - Duration of Sea Grant Regional Consortium designation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Duration of Sea Grant Regional... REGULATIONS SEA GRANTS § 918.6 Duration of Sea Grant Regional Consortium designation. Designation will be made... consistent with the goals of the Act. Continuation of the Sea Grant Regional Consortium designation is...

15 CFR 918.6 - Duration of Sea Grant Regional Consortium designation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Duration of Sea Grant Regional... REGULATIONS SEA GRANTS § 918.6 Duration of Sea Grant Regional Consortium designation. Designation will be made... consistent with the goals of the Act. Continuation of the Sea Grant Regional Consortium designation is...

15 CFR 918.6 - Duration of Sea Grant Regional Consortium designation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Duration of Sea Grant Regional... REGULATIONS SEA GRANTS § 918.6 Duration of Sea Grant Regional Consortium designation. Designation will be made... consistent with the goals of the Act. Continuation of the Sea Grant Regional Consortium designation is...

The Consortium for Higher Education Tax Reform Report

ERIC Educational Resources Information Center

Center for Postsecondary and Economic Success, 2014

2014-01-01

This White Paper presents the work of the Consortium for Higher Education Tax Reform, a partnership funded by the Bill & Melinda Gates Foundation as part of the second phase of its Reimagining Aid Design and Delivery (RADD) initiative. Consortium partners are the Center for Postsecondary and Economic Success at CLASP, the Education Trust, New…

76 FR 34252 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; IMS Global...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-13

... Production Act of 1993; IMS Global Learning Consortium, Inc. Notice is hereby given that, on May 9, 2011... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications... in this group research project remains open, and IMS Global Learning Consortium, Inc. intends to file...

77 FR 34069 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-08

... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on May 2, 2012... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications... remains open, and IMS Global Learning Consortium, Inc. intends to file additional written notifications...

77 FR 54611 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-05

... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on July 16, 2012... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications.... Membership in this group research project remains open, and IMS Global Learning Consortium, Inc. intends to...

United States Participation in the Pacific Circle Consortium. Final Report.

ERIC Educational Resources Information Center

Northwest Regional Educational Lab., Portland, OR.

The goal of the Pacific Circle Project is to improve international and intercultural understanding among the people and nations of the Pacific. Consortium member countries are Australia, Canada, New Zealand, and the United States. Within the countries are chosen member institutions. Two major types of activities of the consortium are the exchange…

Growth behind the Mirror: The Family Therapy Consortium's Group Process.

ERIC Educational Resources Information Center

Wendorf, Donald J.; And Others

1985-01-01

Charts the development of the Family Therapy Consortium, a group that provides supervision and continuing education in family therapy and explores the peer supervision process at work in the consortium. The focus is on individual and group development, which are seen as complementary aspects of the same growth process. (Author/NRB)

Bioremediation of high molecular weight polyaromatic hydrocarbons co-contaminated with metals in liquid and soil slurries by metal tolerant PAHs degrading bacterial consortium.

PubMed

Thavamani, Palanisami; Megharaj, Mallavarapu; Naidu, Ravi

2012-11-01

Bioremediation of polyaromatic hydrocarbons (PAH) contaminated soils in the presence of heavy metals have proved to be difficult and often challenging due to the ability of toxic metals to inhibit PAH degradation by bacteria. In this study, a mixed bacterial culture designated as consortium-5 was isolated from a former manufactured gas plant (MGP) site. The ability of this consortium to utilise HMW PAHs such as pyrene and BaP as a sole carbon source in the presence of toxic metal Cd was demonstrated. Furthermore, this consortium has proven to be effective in degradation of HMW PAHs even from the real long term contaminated MGP soil. Thus, the results of this study demonstrate the great potential of this consortium for field scale bioremediation of PAHs in long term mix contaminated soils such as MGP sites. To our knowledge this is the first study to isolate and characterize metal tolerant HMW PAH degrading bacterial consortium which shows great potential in bioremediation of mixed contaminated soils such as MGP.

The Historically Black Colleges and Universities/Minority Institutions Environmental Technology Consortium annual report 1994--1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-07-01

The HBCU/MI ET Consortium was established in January 1990, through a Memorandum of Understanding (MOU) among its member institutions. This group of research oriented Historically Black Colleges and Universities and Minority Institutions (HBCU/MIs) agreed to work together to initiate or revise education programs, develop research partnerships with public and private sector organizations, and promote technology development to address the nation`s critical environmental contamination problems. The Consortium`s Research, Education and Technology Transfer (RETT) Plan became the working agenda. The Consortium is a resource for collaboration among the member institutions and with federal an state agencies, national and federal laboratories, industries, (includingmore » small businesses), majority universities, and two and four-year technical colleges. As a group of 17 institutions geographically located in the southern US, the Consortium is well positioned to reach a diverse group of women and minority populations of African Americans, Hispanics and American Indians. This Report provides a status update on activities and achievements in environmental curriculum development, outreach at the K--12 level, undergraduate and graduate education, research and development, and technology transfer.« less

Governing boards and profound organizational change in hospitals.

PubMed

Fennell, M L; Alexander, J A

1989-01-01

Over the past decade the importance of governing boards as policy-making setting and oversight units within organizations has increased dramatically. Although this is true for both corporate- and private-sector organizations (Bacon and Brown 1977; Gelman 1988), it is particularly relevant to the health sector. Hospital governing boards, long considered inconsequential in hospital management, have recently become subject to closer scrutiny. The role of governing boards in decisions affecting hospital strategy and hospital performance is once again a topic of some interest in boardrooms and hospital trade journals. Impressive evidence of the renewed interest in governance is provided by the funding of an instructional consortium by the S.K. Kellogg Foundation to help strengthen trusteeship and governing board decision making, and to improve education for health services managers in the area of governance. Members of the consortium include the Hospital Research and Educational Trust, the American Hospital Association, the American College of Healthcare Executives, and the Association for University Programs in Health Administration. Among the activities being undertaken by this consortium is the development of a self-assessment tool/methodology for boards, a bibliography and reference guide on effective governance for practicing trustees, research workshops for faculty in health administration programs, and a teaching guide on governance and trustee leadership. Despite this interest, the question with which we began this article persists. Do governing boards make a difference? In the course of our review of previous work on governance we found that, more often than not, that question has been transformed into: how do boards influence hospital performance? And very often that question has been further narrowed into: which board structure leads to better hospital performance? We have argued for a respecification of the initial question. Rather than pursuing a definition of the maximally performing governing board, we should perhaps shift our focus back to a fuller understanding of board structure and function, and its influence on hospital change. The model developed here combines four essential, and very basic, questions: 1. What are the basic dimensions that underlie structural variation in different types of governing boards? 2. How do these board types influence structural change in hospitals? 3. How is the effect of board influence on change itself likely to change over time as a function of the hospital's general pattern of growth, decline, stability, or instability?(ABSTRACT TRUNCATED AT 400 WORDS)

CDEP Consortium on Ocean Data Assimilation for Seasonal-to-Interannual Prediction (ODASI)

NASA Technical Reports Server (NTRS)

Rienecker, Michele; Zebiak, Stephen; Kinter, James; Behringer, David; Rosati, Antonio; Kaplan, Alexey

2005-01-01

The ODASI consortium is focused activity of the NOAA/OGP/Climate Diagnostics and Experimental Prediction Program with the goal of improving ocean data assimilation methods and their implementations in support of seasonal forecasts with coupled general circulation models. The consortium is undertaking coordinated assimilation experiments, with common forcing data sets and common input data streams. With different assimilation systems and different models, we aim to understand what approach works best in improving forecast skill in the equatorial Pacific. The presentation will provide an overview of the consortium goals and plans and recent results focused towards evaluating data impacts.

Prostate Cancer Clinical Consortium Clinical Research Site: Targeted Therapies

DTIC Science & Technology

2016-10-01

2016 4 . TITLE AND SUBTITLE 5a. CONTRACT NUMBER Prostate Cancer Clinical Consortium Clinical Research Site: Targeted Therapies 5b. GRANT NUMBER 5c...new biomarker driven trials directly to patients W81XWH-14-2-0159 None listed 20 Table of Contents Page 1. Introduction…………………………………………………………. 4 2...Keywords……………………………………………………………. 4 3. Accomplishments ..……..…………………………………………... 4 4 . Impact…………………………...…………………………………… 8 5. Changes/Problems

Results From the John Glenn Biomedical Engineering Consortium. A Success Story for NASA and Northeast Ohio

NASA Technical Reports Server (NTRS)

Nall, Marsha M.; Barna, Gerald J.

2009-01-01

The John Glenn Biomedical Engineering Consortium was established by NASA in 2002 to formulate and implement an integrated, interdisciplinary research program to address risks faced by astronauts during long-duration space missions. The consortium is comprised of a preeminent team of Northeast Ohio institutions that include Case Western Reserve University, the Cleveland Clinic, University Hospitals Case Medical Center, The National Center for Space Exploration Research, and the NASA Glenn Research Center. The John Glenn Biomedical Engineering Consortium research is focused on fluid physics and sensor technology that addresses the critical risks to crew health, safety, and performance. Effectively utilizing the unique skills, capabilities and facilities of the consortium members is also of prime importance. Research efforts were initiated with a general call for proposals to the consortium members. The top proposals were selected for funding through a rigorous, peer review process. The review included participation from NASA's Johnson Space Center, which has programmatic responsibility for NASA's Human Research Program. The projects range in scope from delivery of prototype hardware to applied research that enables future development of advanced technology devices. All of the projects selected for funding have been completed and the results are summarized. Because of the success of the consortium, the member institutions have extended the original agreement to continue this highly effective research collaboration through 2011.

Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.

PubMed

Tielbeek, Jorim J; Johansson, Ada; Polderman, Tinca J C; Rautiainen, Marja-Riitta; Jansen, Philip; Taylor, Michelle; Tong, Xiaoran; Lu, Qing; Burt, Alexandra S; Tiemeier, Henning; Viding, Essi; Plomin, Robert; Martin, Nicholas G; Heath, Andrew C; Madden, Pamela A F; Montgomery, Grant; Beaver, Kevin M; Waldman, Irwin; Gelernter, Joel; Kranzler, Henry R; Farrer, Lindsay A; Perry, John R B; Munafò, Marcus; LoParo, Devon; Paunio, Tiina; Tiihonen, Jari; Mous, Sabine E; Pappa, Irene; de Leeuw, Christiaan; Watanabe, Kyoko; Hammerschlag, Anke R; Salvatore, Jessica E; Aliev, Fazil; Bigdeli, Tim B; Dick, Danielle; Faraone, Stephen V; Popma, Arne; Medland, Sarah E; Posthuma, Danielle

2017-12-01

Antisocial behavior (ASB) places a large burden on perpetrators, survivors, and society. Twin studies indicate that half of the variation in this trait is genetic. Specific causal genetic variants have, however, not been identified. To estimate the single-nucleotide polymorphism-based heritability of ASB; to identify novel genetic risk variants, genes, or biological pathways; to test for pleiotropic associations with other psychiatric traits; and to reevaluate the candidate gene era data through the Broad Antisocial Behavior Consortium. Genome-wide association data from 5 large population-based cohorts and 3 target samples with genome-wide genotype and ASB data were used for meta-analysis from March 1, 2014, to May 1, 2016. All data sets used quantitative phenotypes, except for the Finnish Crime Study, which applied a case-control design (370 patients and 5850 control individuals). This study adopted relatively broad inclusion criteria to achieve a quantitative measure of ASB derived from multiple measures, maximizing the sample size over different age ranges. The discovery samples comprised 16 400 individuals, whereas the target samples consisted of 9381 individuals (all individuals were of European descent), including child and adult samples (mean age range, 6.7-56.1 years). Three promising loci with sex-discordant associations were found (8535 female individuals, chromosome 1: rs2764450, chromosome 11: rs11215217; 7772 male individuals, chromosome X, rs41456347). Polygenic risk score analyses showed prognostication of antisocial phenotypes in an independent Finnish Crime Study (2536 male individuals and 3684 female individuals) and shared genetic origin with conduct problems in a population-based sample (394 male individuals and 431 female individuals) but not with conduct disorder in a substance-dependent sample (950 male individuals and 1386 female individuals) (R2 = 0.0017 in the most optimal model, P = 0.03). Significant inverse genetic correlation of ASB with educational attainment (r = -0.52, P = .005) was detected. The Broad Antisocial Behavior Consortium entails the largest collaboration to date on the genetic architecture of ASB, and the first results suggest that ASB may be highly polygenic and has potential heterogeneous genetic effects across sex.

Promoting Children's Social-Emotional Skills in Preschool Can Enhance Academic and Behavioral Functioning in Kindergarten: Findings from Head Start REDI

PubMed Central

Nix, Robert L.; Bierman, Karen L.; Domitrovich, Celene E.; Gill, Sukhdeep

2013-01-01

This study examined processes of change associated with the positive preschool and kindergarten outcomes of children who received the Head Start REDI intervention, compared to “usual practice” Head Start. In a large-scale randomized-controlled trial (N = 356 children, 42% African American or Latino, all from low-income families), this study tests the logic model that improving preschool social-emotional skills (e.g., emotion understanding, social problem solving, and positive social behavior) as well as language/emergent literacy skills will promote cross-domain academic and behavioral adjustment after children transition into kindergarten. Validating this logic model, the present study finds that intervention effects on three important kindergarten outcomes (e.g., reading achievement, learning engagement, and positive social behavior) were mediated by preschool gains in the proximal social-emotional and language/emergent literacy skills targeted by the REDI intervention. Importantly, preschool gains in social-emotional skills made unique contributions to kindergarten outcomes in reading achievement and learning engagement, even after accounting for the concurrent preschool gains in vocabulary and emergent literacy skills. These findings highlight the importance of fostering at-risk children's social-emotional skills during preschool as a means of promoting school readiness. The REDI (Research-Based, Developmentally-Informed) enrichment intervention was designed to complement and strengthen the impact of existing Head Start programs in the dual domains of language/emergent literacy skills and social-emotional competencies. REDI was one of several projects funded by the Interagency School Readiness Consortium, a partnership of four federal agencies (the National Institute of Child Health and Human Development, the Administration for Children and Families, the Assistant Secretary for Planning and Evaluation in the Department of Health and Human Services, and the Office of Special Education and Rehabilitation Services in the Department of Education). The projects funded through this partnership were designed to assess how integrative early interventions for at-risk children could promote learning and development across multiple domains of functioning. In addition, the projects were charged with examining processes of change and identifying mechanisms of action by which the early childhood interventions fostered later school adjustment and academic achievement. This study examined such processes of change, with the goal of documenting hypothesized cross-domain influences on kindergarten outcomes. In particular, this study tested whether gains in the proximal language/emergent literacy and social-emotional competencies targeted during Head Start would mediate the REDI intervention effects on kindergarten academic and behavioral outcomes. In addition, it tested the hypothesis that gains in social-emotional competencies during preschool would make unique contributions to intervention effects on both academic and behavioral outcomes, even after accounting for the effects of preschool gains in language and emergent literacy skills. PMID:24311939

Consortium of States to Upgrade Indian Education through State Departments of Education. Second-Year Report, May 1977.

ERIC Educational Resources Information Center

Mueller, Mildred K.

Presenting information regarding second-year activities of the Consortium of States to Upgrade Indian Education through State Departments of Education, this report includes the following: acknowledgments; data re: funding; background; second-year consortium activities; participation (a map depicting the 13-state membership and a list of Consortium…

25 CFR 1000.171 - When should a Tribe/Consortium submit a letter of interest?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false When should a Tribe/Consortium submit a letter of... of Initial Annual Funding Agreements § 1000.171 When should a Tribe/Consortium submit a letter of... BIA by April 1 for fiscal year Tribes/Consortia or May 1 for calendar year Tribes/Consortia. ...

25 CFR 1000.21 - When does a Tribe/Consortium have a “material audit exception”?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false When does a Tribe/Consortium have a âmaterial audit... SELF-DETERMINATION AND EDUCATION ACT Selection of Additional Tribes for Participation in Tribal Self-Governance Eligibility § 1000.21 When does a Tribe/Consortium have a “material audit exception”? A Tribe...

25 CFR 1000.171 - When should a Tribe/Consortium submit a letter of interest?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false When should a Tribe/Consortium submit a letter of... of Initial Annual Funding Agreements § 1000.171 When should a Tribe/Consortium submit a letter of... BIA by April 1 for fiscal year Tribes/Consortia or May 1 for calendar year Tribes/Consortia. ...

25 CFR 1000.21 - When does a Tribe/Consortium have a “material audit exception”?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false When does a Tribe/Consortium have a âmaterial audit... SELF-DETERMINATION AND EDUCATION ACT Selection of Additional Tribes for Participation in Tribal Self-Governance Eligibility § 1000.21 When does a Tribe/Consortium have a “material audit exception”? A Tribe...

Wisconsin Area Planning and Development. Consortium Project, Title I, Higher Education Act 1965.

ERIC Educational Resources Information Center

Wisconsin Univ., Madison. Univ. Extension.

The Consortium for Area Planning and Development was established in 1967 to implement the basic purposes of Title I of the Higher Education Act of 1965. The Consortium's first seminar was held in May 1968 and was attended by 25 project leaders, local and state government officials, technical consultants, and representatives of various institutions…

Cyber Intelligence Research Consortium (Poster)

DTIC Science & Technology

2014-10-24

OCT 2014 2. REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE Cyber Intelligence Research Consortium Poster 5a. CONTRACT NUMBER 5b...nontechnical audiences Environmental Context Provides scope for the analytical effort • Highlights the importance of context - technical and nontechnical... Environmental Context Reporting & Feedback Macroanalysis Microanalysis Data Gathering Steering Committee: Guide Consortium activities and plan for future

Third-Party Evaluation 1977-1978 of the ACCTion Consortium: A Technical Assistance Project for Two-Year Institutions. Volume I.

ERIC Educational Resources Information Center

Enterprises for New Directions, Inc., Washington, DC.

In accordance with federally mandated evaluation requirements, Enterprises for New Directions (END), Inc., was requested to conduct a summative external evaluation of the 1977-78 Association of Community College Trustees (ACCTion) Consortium. The Consortium consists of 114 two-year colleges nationwide which receive technical assistance through…

24 CFR 943.126 - What is the relationship between HUD and a consortium?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false What is the relationship between... § 943.126 What is the relationship between HUD and a consortium? HUD has a direct relationship with the consortium through the PHA Plan process and through one or more payment agreements, executed in a form...

24 CFR 943.126 - What is the relationship between HUD and a consortium?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false What is the relationship between... § 943.126 What is the relationship between HUD and a consortium? HUD has a direct relationship with the consortium through the PHA Plan process and through one or more payment agreements, executed in a form...

24 CFR 943.126 - What is the relationship between HUD and a consortium?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false What is the relationship between... § 943.126 What is the relationship between HUD and a consortium? HUD has a direct relationship with the consortium through the PHA Plan process and through one or more payment agreements, executed in a form...

24 CFR 943.126 - What is the relationship between HUD and a consortium?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false What is the relationship between... § 943.126 What is the relationship between HUD and a consortium? HUD has a direct relationship with the consortium through the PHA Plan process and through one or more payment agreements, executed in a form...

24 CFR 943.126 - What is the relationship between HUD and a consortium?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What is the relationship between... § 943.126 What is the relationship between HUD and a consortium? HUD has a direct relationship with the consortium through the PHA Plan process and through one or more payment agreements, executed in a form...

34 CFR 636.5 - What are the matching contribution and planning consortium requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false What are the matching contribution and planning... PROGRAM General § 636.5 What are the matching contribution and planning consortium requirements? (a) The... agreed to by the members of a planning consortium. (Authority: 20 U.S.C. 1136b, 1136e) ...

Measuring Consortium Impact on User Perceptions: OhioLINK and LibQUAL+[TM

ERIC Educational Resources Information Center

Gatten, Jeffrey N.

2004-01-01

What is the impact of an academic library consortium on the perceptions of library services experienced by users of the member institutions' libraries? What is the impact of an academic library consortium on the perceptions of library services experienced by users of the member institutions libraries? In 2002 and 2003, OhioLINK (Ohio's consortium…

Enriching Doctoral-Level Preparation Programs through a Nationwide Consortium Model: The National Leadership Consortium in Sensory Disabilities

ERIC Educational Resources Information Center

Kruemmling, Brooke; Hayes, Heather; Smith, Derrick W.

2017-01-01

The National Leadership Consortium in Sensory Disabilities (NLCSD) trained doctoral scholars at universities across the United States to increase the number and quality of professionals specializing in educating children with sensory disabilities. NLCSD produced 40 new doctorates and created a community of learners comprised of scholars, faculty,…

42 CFR 137.235 - May an Indian Tribe withdraw from a participating inter-Tribal consortium or Tribal organization?

Code of Federal Regulations, 2011 CFR

2011-10-01

... inter-Tribal consortium or Tribal organization? 137.235 Section 137.235 Public Health PUBLIC HEALTH... SERVICES TRIBAL SELF-GOVERNANCE Withdrawal § 137.235 May an Indian Tribe withdraw from a participating inter-Tribal consortium or Tribal organization? Yes, an Indian Tribe may fully or partially withdraw...

42 CFR 137.235 - May an Indian Tribe withdraw from a participating inter-Tribal consortium or Tribal organization?

Code of Federal Regulations, 2010 CFR

2010-10-01

... inter-Tribal consortium or Tribal organization? 137.235 Section 137.235 Public Health PUBLIC HEALTH... SERVICES TRIBAL SELF-GOVERNANCE Withdrawal § 137.235 May an Indian Tribe withdraw from a participating inter-Tribal consortium or Tribal organization? Yes, an Indian Tribe may fully or partially withdraw...

42 CFR 137.235 - May an Indian Tribe withdraw from a participating inter-Tribal consortium or Tribal organization?

Code of Federal Regulations, 2014 CFR

2014-10-01

... inter-Tribal consortium or Tribal organization? 137.235 Section 137.235 Public Health PUBLIC HEALTH... SERVICES TRIBAL SELF-GOVERNANCE Withdrawal § 137.235 May an Indian Tribe withdraw from a participating inter-Tribal consortium or Tribal organization? Yes, an Indian Tribe may fully or partially withdraw...

32 CFR 37.515 - Must I do anything additional to determine the qualification of a consortium?

Code of Federal Regulations, 2014 CFR

2014-07-01

... SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 37.515 Must I do anything additional to determine the qualification of a consortium? (a) When the prospective recipient of a TIA is a consortium that is not formally incorporated...

32 CFR 37.515 - Must I do anything additional to determine the qualification of a consortium?

Code of Federal Regulations, 2012 CFR

2012-07-01

... SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 37.515 Must I do anything additional to determine the qualification of a consortium? (a) When the prospective recipient of a TIA is a consortium that is not formally incorporated...

32 CFR 37.515 - Must I do anything additional to determine the qualification of a consortium?

Code of Federal Regulations, 2013 CFR

2013-07-01

... SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 37.515 Must I do anything additional to determine the qualification of a consortium? (a) When the prospective recipient of a TIA is a consortium that is not formally incorporated...

A Long Island Consortium Takes Shape. Occasional Paper No. 76-1.

ERIC Educational Resources Information Center

Taylor, William R.

This occasional paper, the first in a "new" series, describes the background, activities, and experiences of the Long Island Consortium, a cooperative effort of two-year and four-year colleges committed to organizing a model program of faculty development. The consortium was organized under an initial grant from the Lilly Endowment. In May and…

Baltimore Education Research Consortium: A Consideration of Past, Present, and Future

ERIC Educational Resources Information Center

Connolly, Faith; Plank, Stephen; Rone, Tracy

2012-01-01

In this paper, we offer an overview of the history and development of the Baltimore Education Research Consortium (BERC). As a part of this overview, we describe challenges and dilemmas encountered during the founding years of this consortium. We also highlight particular benefits or sources of satisfaction we have realized in the course of…

25 CFR 1000.68 - May non-BIA bureaus provide technical assistance to a Tribe/Consortium in drafting its planning...

Code of Federal Regulations, 2010 CFR

2010-04-01

... Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application... Tribe/Consortium in drafting its planning grant application? 1000.68 Section 1000.68 Indians OFFICE OF... planning grant application? Yes, upon request from the Tribe/Consortium, a non-BIA bureau may provide...

76 FR 4723 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-26

... Production Act of 1993--IMS Global Learning Consortium, Inc. Correction In notice document 2011-78 appearing... sixth lines, ``INS Global Learning Consortium, Inc.'' should read ``IMS Global Learning Consortium, Inc.''. 3. On the same page, in the third column, in the 15th and 16th lines, ``INS Global Learning...

Third Progress and Information Report of the Vocational-Technical Education Consortium of States.

ERIC Educational Resources Information Center

Lee, Connie W.; And Others

This description of major activities and accomplishments of the Vocational-Technical Education Consortium of the States (V-TECS) since the second progress report of May, 1975, is designed to provide the reader with a basic understanding of the processes and procedures used by the consortium in achieving its major goal: The production of catalogs…

76 FR 20633 - Announcement of Meeting to Explore Feasibility of Establishing a NIST/Industry Consortium on...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... Explore Feasibility of Establishing a NIST/Industry Consortium on Neutron Measurements for Soft Materials.... SUMMARY: The National Institute of Standards and Technology (NIST) invites interested parties to attend a pre-consortium meeting on June 2-3, 2011 to be held on the NIST campus. The goal of the one-day...

Pacific Eisenhower Mathematics and Science Regional Consortium Final Performance Report, October 1, 1995-February 28, 2001.

ERIC Educational Resources Information Center

Pacific Resources for Education and Learning, Honolulu, HI.

The Pacific Eisenhower Mathematics and Science Regional Consortium was established at Pacific Resources for Education and Learning (PREL) in October, 1992 and completed its second funding cycle in February 2001. The Consortium is a collaboration among PREL, the Curriculum Research and Development Group (CRDG) at the University of Hawaii, and the…

25 CFR 1000.367 - Will the Department evaluate a Tribe's/Consortium's performance of non-trust related programs?

Code of Federal Regulations, 2010 CFR

2010-04-01

... Evaluations § 1000.367 Will the Department evaluate a Tribe's/Consortium's performance of non-trust related... 25 Indians 2 2010-04-01 2010-04-01 false Will the Department evaluate a Tribe's/Consortium's performance of non-trust related programs? 1000.367 Section 1000.367 Indians OFFICE OF THE ASSISTANT SECRETARY...

Evaluation Report for the Massachusetts Workplace Literacy Consortium. National Workplace Literacy Program Wave 6, Year 3.

ERIC Educational Resources Information Center

Sperazi, Laura; DePascale, Charles A.

The Massachusetts Workplace Literacy Consortium sought to upgrade work-related literacy skills at 22 partner sites in the state. Members included manufacturers, health care organizations, educational institutions, and labor unions. In its third year, the consortium served 1,179 workers with classes in English for speakers of other languages, adult…

Coastal Change Along the Shore of Northeastern South Carolina - The South Carolina Coastal Erosion Study

USGS Publications Warehouse

Schwab, W.C.; Gayes, P.T.; Morton, R.A.; Driscoll, N.W.; Baldwin, W.E.; Barnhardt, W.A.; Denny, J.F.; Harris, M.S.; Katuna, M.P.; Putney, T.R.; Voulgaris, G.; Warner, J.C.; Wright, E.E.; Barnhardt, Walter A.

2009-01-01

The U.S. Geological Survey, in cooperation with the South Carolina Sea Grant Consortium, conducted a 7-year, multidisciplinary study of coastal erosion in northeastern South Carolina. Shoreline behavior along the coast of Long Bay is dictated by waves, tidal currents, and sediment supply that act within the overall constraints of the regional geologic setting. Beaches are thin ribbons of sand that sit on top of layered sedimentary rocks, which have been deeply eroded by rivers and coastal processes over millions of years. Offshore of the beaches, these sedimentary rocks are exposed as hardgrounds over large expanses of shallow seafloor and are locally overlain by a discontinuous veneer of sandy sediment generally less than 1 m thick. Rates of shoreline retreat largely depend on the geologic framework of the shoreface that is being excavated by ocean processes. Mainland-attached beaches have remained relatively stable, whereas barrier islands have experienced large shifts in shoreline position. In this sediment-limited region, erosion of the shoreface and inner shelf probably contributes a significant amount of new material to the beach system. Oceanographic studies and numerical modeling show that sediment transport varies along the coast, depending on the type and travel path of storms that impact Long Bay, but the long-term net transport direction is generally from north to south. Changes in storm activity that might accompany climate change, coupled with anticipated increases in sea-level rise, are expected to strongly affect low-lying, heavily developed areas of the coast.

Monitoring Period and Amplitude Changes in Classical Cepheids

NASA Astrophysics Data System (ADS)

Erickson, Mary; Engle, Scott; Guinan, Edward; Wells, Mark

2018-01-01

Classical Cepheids are a specific class of radially pulsating variable stars and are fundamentally important to Astronomy and Cosmology. Their pulsations can be used to determine accurate distances, both inside the Milky Way and to other galaxies throughout the Universe, via the well-studied Period-Luminosity Relationship (the Leavitt Law). This makes Cepheids “standard candles,” and they are helping Astronomers refine the expansion rate and age of the Universe.Though Cepheid pulsations were long-theorized to be completely stable, we now know that they undergo small but observable changes in their pulsation periods. The rates of the period change give us invaluable information on the Cepheids themselves, and the advent of reliable all-sky photometry surveys has allowed Cepheid pulsations to be monitored more easily than ever before.Five Cepheids were analyzed for this study – AA Gem, BB Gem, RZ Gem, AD Gem, and DX Gem. Photometric data were obtained from two sources: ASAS (the All-Sky Automated Survey) and the RCT (Robotically Controlled Telescope) at Kitt Peak National Observatory in Arizona, whose consortium Villanova is a member of. This photometry is combined with available data from the literature. The two instruments combined give a longer time span, and increased precision, from which period variations can be monitored. This gives us an excellent look at how the pulsations of these 5 Cepheids are evolving over time. The pulsation behavior of the 5 Cepheids studies will be presented, along with their calculated stellar parameters.

The response of maize (Zea mays L.) plant assisted with bacterial consortium and fertilizer under oily sludge.

PubMed

Shahzad, Asim; Saddiqui, Samina; Bano, Asghari

2016-01-01

The objective of this study was to evaluate the role of PGPR consortium and fertilizer alone and in combination on the physiology of maize grown under oily sludge stress environment as well on the soil nutrient status. Consortium was prepared from Bacillus cereus (Acc KR232400), Bacillus altitudinis (Acc KF859970), Comamonas (Delftia) belonging to family Comamonadacea (Acc KF859971) and Stenotrophomonasmaltophilia (Acc KF859973). The experiment was conducted in pots with complete randomized design with four replicates and kept in field. Oily sludge was mixed in ml and Ammonium nitrate and Diammonium phosphate (DAP) were added at 70 ug/g and 7 ug/g at sowing. The plant was harvested at 21 d for estimation of protein, proline and antioxidant enzymes superoxide dismutase (SOD) and peroxidase (POD). To study the degradation, total petroleum hydrocarbon was extracted by soxhelt extraction and extract was analyzed by GC-FID at different period after incubation. Combined application of consortium and fertilizer enhanced the germination %, protein and, proline content by 90,130 and 99% higher than untreated maize plants. Bioavailability of macro and micro nutrient was also enhanced with consortium and fertilizer in oily sludge. The consortium and fertilizer in combined treatment decreased the superoxide dismutase (SOD), peroxidase dismutase (POD) of the maize leaves grown in oily sludge. Degradation of total petroleum hydrocarbon (TPHs) was 59% higher in combined application of consortium and fertilizer than untreated maize at 3 d. The bacterial consortium can enhanced the maize tolerance to oily sludge and enhanced degradation of total petroleum hydrocarbon (TPHs). The maize can be considered as tolerant plant species to remediate oily sludge contaminated soils.

Patient-Reported Outcome (PRO) Consortium translation process: consensus development of updated best practices.

PubMed

Eremenco, Sonya; Pease, Sheryl; Mann, Sarah; Berry, Pamela

2017-01-01

This paper describes the rationale and goals of the Patient-Reported Outcome (PRO) Consortium's instrument translation process. The PRO Consortium has developed a number of novel PRO measures which are in the process of qualification by the U.S. Food and Drug Administration (FDA) for use in clinical trials where endpoints based on these measures would support product labeling claims. Given the importance of FDA qualification of these measures, the PRO Consortium's Process Subcommittee determined that a detailed linguistic validation (LV) process was necessary to ensure that all translations of Consortium-developed PRO measures are performed using a standardized approach with the rigor required to meet regulatory and pharmaceutical industry expectations, as well as having a clearly defined instrument translation process that the translation industry can support. The consensus process involved gathering information about current best practices from 13 translation companies with expertise in LV, consolidating the findings to generate a proposed process, and obtaining iterative feedback from the translation companies and PRO Consortium member firms on the proposed process in two rounds of review in order to update existing principles of good practice in LV and to provide sufficient detail for the translation process to ensure consistency across PRO Consortium measures, sponsors, and translation companies. The consensus development resulted in a 12-step process that outlines universal and country-specific new translation approaches, as well as country-specific adaptations of existing translations. The PRO Consortium translation process will play an important role in maintaining the validity of the data generated through these measures by ensuring that they are translated by qualified linguists following a standardized and rigorous process that reflects best practice.

Response surface methodology for optimization of medium for decolorization of textile dye Direct Black 22 by a novel bacterial consortium.

PubMed

Mohana, Sarayu; Shrivastava, Shalini; Divecha, Jyoti; Madamwar, Datta

2008-02-01

Decolorization and degradation of polyazo dye Direct Black 22 was carried out by distillery spent wash degrading mixed bacterial consortium, DMC. Response surface methodology (RSM) involving a central composite design (CCD) in four factors was successfully employed for the study and optimization of decolorization process. The hyper activities and interactions between glucose concentration, yeast extract concentration, dye concentration and inoculum size on dye decolorization were investigated and modeled. Under optimized conditions the bacterial consortium was able to decolorize the dye almost completely (>91%) within 12h. Bacterial consortium was able to decolorize 10 different azo dyes. The optimum combination of the four variables predicted through RSM was confirmed through confirmatory experiments and hence this bacterial consortium holds potential for the treatment of industrial waste water. Dye degradation products obtained during the course of decolorization were analyzed by HPTLC.

Formulation of bacterial consortium as whole cell biocatalyst for degradation of oil compounds

NASA Astrophysics Data System (ADS)

Yetti, Elvi; A'la, Amalia; Luthfiyah, Nailul; Wijaya, Hans; Thontowi, Ahmad; Yopi

2017-11-01

In this research, weaim to investigateformulation of bacterial consortium as whole cell biocatalyst for degradation of oil compounds. We constructed microbial consortium from 4 (four) selected marine oil bacteria to become 15 (twelve) combination culture. Those bacteria were from collection of Laboratory of Biocatalyst and Fermentation, Research Center for Biotechnology, Indonesian Institutes of Sciences and designated as Labrenzia sp. MBTDCMFRIMab26, Labrenzia aggregata strasin HQB397, Novosphingobium pentaromativorans strain PQ-3 16S, and Novosphingobium pentaromativorans strain US6-1. The mixture or bacteria consortia, denoted as F1, F2, …F15 consisted of 1, 2, 3 and 4 bacterial strains, respectively. The strains were selected based on the criteria that they were able to display good growth in crude oil containing media. Five bacterialformulationsshowed good potentialas candidates for microbial consortium. We will optimize these consortium with carrier matrix choosed from biomass materials and also carry out oil content analysis.

The bioleaching potential of a bacterial consortium.

PubMed

Latorre, Mauricio; Cortés, María Paz; Travisany, Dante; Di Genova, Alex; Budinich, Marko; Reyes-Jara, Angélica; Hödar, Christian; González, Mauricio; Parada, Pilar; Bobadilla-Fazzini, Roberto A; Cambiazo, Verónica; Maass, Alejandro

2016-10-01

This work presents the molecular foundation of a consortium of five efficient bacteria strains isolated from copper mines currently used in state of the art industrial-scale biotechnology. The strains Acidithiobacillus thiooxidans Licanantay, Acidiphilium multivorum Yenapatur, Leptospirillum ferriphilum Pañiwe, Acidithiobacillus ferrooxidans Wenelen and Sulfobacillus thermosulfidooxidans Cutipay were selected for genome sequencing based on metal tolerance, oxidation activity and bioleaching of copper efficiency. An integrated model of metabolic pathways representing the bioleaching capability of this consortium was generated. Results revealed that greater efficiency in copper recovery may be explained by the higher functional potential of L. ferriphilum Pañiwe and At. thiooxidans Licanantay to oxidize iron and reduced inorganic sulfur compounds. The consortium had a greater capacity to resist copper, arsenic and chloride ion compared to previously described biomining strains. Specialization and particular components in these bacteria provided the consortium a greater ability to bioleach copper sulfide ores. Copyright © 2016 Elsevier Ltd. All rights reserved.

Advanced Medical Countermeasures Consortium

DTIC Science & Technology

2010-10-01

acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral Nutrition in ARDS Study Group. Crit Care Med...molecular mechanism of action, and (3) efficacy of countermeasures for HD injury. Studies on the Yucatan mini-pig have demonstrated that laminin in...Lindsay CD, Rice P. Changes in connective tissue macromolecular components of Yucatan mini-pig skin following application of sulphur mustard vapour. Hum

Development of a Curriculum to Meet Changing Manpower Needs of the Computer and Business Machine Industries; Interim Developments. Final Report.

ERIC Educational Resources Information Center

Lescarbeau, Roland F.; And Others

This suggested curriculum guide represents the consensus of opinion by the representatives of seven schools comprising the Technical Education Consortium, with advice of industrial experts concerning the essential educational needs of the technicians they would employ. It will serve as a guide to schools planning to institute a program applicable…

Engaging Students in Science Courses: Lessons of Change from the Arctic

ERIC Educational Resources Information Center

Duffy, Lawrence K.; Godduhn, Anna; Fabbri, Cindy E.; van Muelken, Mary; Nicholas-Figueroa, Linda; Middlecamp, Catherine Hurt

2011-01-01

Where you live should have something to do with what you teach. In the Arctic, the idea of place-based education--teaching and sharing knowledge that is needed to live well--is central to the UARCTIC consortium and the 4th International Polar Year educational reform effort. A place-based issue oriented context can engage students in chemistry…

The Consortium on the Genetics of Schizophrenia: Neurocognitive Endophenotypes

PubMed Central

Gur, Raquel E.; Calkins, Monica E.; Gur, Ruben C.; Horan, William P.; Nuechterlein, Keith H.; Seidman, Larry J.; Stone, William S.

2007-01-01

The Consortium on the Genetics of Schizophrenia (COGS) is a 7-site collaboration that examines the genetic architecture of quantitative endophenotypes in families with schizophrenia. Here we review the background and rationale for selecting neurocognitive tasks as endophenotypic measures in genetic studies. Criteria are outlined for the potential of measures as endophenotypic vulnerability markers. These include association with illness, state independence (ie, adequate test-retest stability, adequate between-site reliability, impairments in patients not due to medications, impairments observed regardless of illness state), heritability, findings of higher rates in relatives of probands than in the general population, and cosegregation within families. The COGS required that, in addition, the measures be “neurocognitive” and thus linked to neurobiology and that they be feasible in multisite studies. The COGS neurocognitive assessment includes measures of attention, verbal memory, working memory, and a computerized neurocognitive battery that also includes facial processing tasks. Here we describe data demonstrating that these neurobehavioral measures meet criteria for endophenotypic candidacy. We conclude that quantitative neurocognitive endophenotypes need further evidence for efficacy in identifying genetic effects but have the potential of providing unprecedented insight into gene-environment interaction related to dimensions of brain and behavior in health and disease. PMID:17101692

The influence of pre-existing rib fractures on Global Human Body Models Consortium thorax response in frontal and oblique impact.

PubMed

Zaseck, Lauren Wood; Chen, Cong; Hu, Jingwen; Reed, Matthew P; Rupp, Jonathan

2018-03-01

Many post-mortem human subjects (PMHS) considered for use in biomechanical impact tests have pre-existing rib fractures (PERFs), usually resulting from cardiopulmonary resuscitation. These specimens are typically excluded from impact studies with the assumption that the fractures will alter the thoracic response to loading. We previously used the Global Human Body Models Consortium 50th percentile whole-body finite element model (GHBMC M50-O) to demonstrate that up to three lateral or bilateral PERFs do not meaningfully influence the response of the GHBMC thorax to lateral loading. This current study used the GHBMC M50-O to explore the influence of PERFs on thorax response in frontal and oblique loading. Up to six PERFs were simulated on the anterior or lateral rib regions, and the model was subjected to frontal or oblique cylindrical impactor, frontal seatbelt, or frontal seatbelt + airbag loading. Changes in thorax force-compression responses due to PERFs were generally minor, with the greatest alterations seen in models with six PERFs on one side of the ribcage. The observed changes, however, were small relative to mid-size male corridors for the loading conditions simulated. PERFs altered rib strain patterns, but the changes did not translate to changes in global thoracic response. Within the limits of model fidelity, the results suggest that PMHS with up to six PERFs may be appropriate for use in frontal or oblique impact testing. Copyright © 2018 Elsevier Ltd. All rights reserved.

The transnational circulation of scientific ideas: importing behavioralism in European political science (1950-1970).

PubMed

Boncourt, Thibaud

2015-01-01

This article aims to deepen our understanding of the transatlantic circulation of scientific ideas during the Cold War by looking at the importation of behavioralism in European political science. It analyses the social, institutional, and intellectual dynamics that led to the creation, in 1970, of a transnational organization that aimed to promote behavioralism in Europe: the European Consortium for Political Research (ECPR). Using qualitative material drawn from archives and interviews, the study shows that the creation of the ECPR was the joint product of academic, scientific, and political rivalries. It argues that the founding of the organization served a purpose for several agents (chiefly, academic entrepreneurs and philanthropic foundations) who pursued different strategies in different social fields in the context of the Cold War. More broadly, it suggests that the postwar development of the social sciences and the circulation of scientific ideas are best accounted for by mapping sociological interactions between scientific fields and neighboring social spheres. © 2015 Wiley Periodicals, Inc.

25 CFR 1000.179 - What happens if the Tribe/Consortium and bureau negotiators fail to reach an agreement?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false What happens if the Tribe/Consortium and bureau negotiators fail to reach an agreement? 1000.179 Section 1000.179 Indians OFFICE OF THE ASSISTANT SECRETARY... and bureau negotiators fail to reach an agreement? (a) If the Tribe/Consortium and bureau...

Consortium for Molecular Characterization of Screen-Detected Lesions Created: Eight Grants Awarded | Division of Cancer Prevention

Cancer.gov

The NCI has awarded eight grants to create the Consortium for Molecular Characterization of Screen-Detected Lesions. The consortium has seven molecular characterization laboratories (MCLs) and a coordinating center, and is supported by the Division of Cancer Prevention and the Division of Cancer Biology. | 7 laboratories and a coordinating center focused on identifying

25 CFR 1000.23 - How is a Tribe/Consortium admitted to the applicant pool?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false How is a Tribe/Consortium admitted to the applicant pool...-DETERMINATION AND EDUCATION ACT Selection of Additional Tribes for Participation in Tribal Self-Governance Admission into the Applicant Pool § 1000.23 How is a Tribe/Consortium admitted to the applicant pool? To be...

25 CFR 1000.23 - How is a Tribe/Consortium admitted to the applicant pool?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How is a Tribe/Consortium admitted to the applicant pool...-DETERMINATION AND EDUCATION ACT Selection of Additional Tribes for Participation in Tribal Self-Governance Admission into the Applicant Pool § 1000.23 How is a Tribe/Consortium admitted to the applicant pool? To be...

32 CFR 37.1015 - How do I decide who must sign the TIA if the recipient is an unincorporated consortium?

Code of Federal Regulations, 2010 CFR

2010-07-01

... sign on behalf of the other participants and are binding on all consortium members with respect to the... signed by a single member on behalf of a consortium that is not a legal entity. For example, you should... sign on all members' behalf. Reporting Information About the Award ...

32 CFR 37.1015 - How do I decide who must sign the TIA if the recipient is an unincorporated consortium?

Code of Federal Regulations, 2011 CFR

2011-07-01

... sign on behalf of the other participants and are binding on all consortium members with respect to the... signed by a single member on behalf of a consortium that is not a legal entity. For example, you should... sign on all members' behalf. Reporting Information About the Award ...

AFT-QuEST Consortium Yearbook. Proceedings of the AFT-QuEST Consortium (April 22-26, 1973).

ERIC Educational Resources Information Center

American Federation of Teachers, Washington, DC.

This document is a report on the proceedings of the 1973 American Federation of Teachers-Quality Educational Standards in Teaching (AFT-QuEST) consortium sponsored by the AFT. Included in this document are the texts of speeches and outlines of workshops and iscussions. The document is divided into the following sections: goals, major proposals,…

The Launch of the Philadelphia Education Research Consortium: Lessons Learned from the First Year of Implementation

ERIC Educational Resources Information Center

Shaw, Kate

2016-01-01

The Philadelphia Education Research Consortium (PERC) was launched in July 2014 as an innovative place-based consortium of educational research partners from multiple sectors. Its primary objective is to provide research and analyses on some of the city's most pressing education issues. As such, PERC's research agenda is driven by both traditional…

The Child Development Training Consortium. A Status Report on the San Juan College AACJC-Kellogg Beacon College Project.

ERIC Educational Resources Information Center

Beers, C. David; Ott, Richard W.

The Child Development Training Consortium, a Beacon College Project directed by San Juan College (SJC) is a collaborative effort of colleges and universities in New Mexico and Arizona. The consortium's major objective is to create child development training materials for community college faculty who teach "at-risk" Native American and…

Activities of the Alabama Consortium on forestry education and research, 1993-1999

Treesearch

John Schelhas

2002-01-01

The Alabama Consortium on Forestry Education and Research was established in 1992 to promote communication and collaboration among diverse institutions involved in forestry in the State of Alabama. It was organized to advance forestry education and research in ways that could not be accomplished by individual members alone. This report tells the story of the consortium...

From Franchise Network to Consortium: The Evolution and Operation of a New Kind of Further and Higher Education Partnership

ERIC Educational Resources Information Center

Bridge, Freda; Fisher, Roy; Webb, Keith

2003-01-01

The Consortium for Post-Compulsory Education and Training (CPCET) is a single subject consortium of further education and higher education providers of professional development relating to in-service teacher training for the whole of the post-compulsory sector. Involving more than 30 partners spread across the North of England, CPCET evolved from…

Prostate Cancer Clinical Consortium Clinical Research Site:Targeted Therapies

DTIC Science & Technology

2015-10-01

AWARD NUMBER: W81XWH-14-2-0159 TITLE: Prostate Cancer Clinical Consortium Clinical Research Site: Targeted Therapies PRINCIPAL INVESTIGATOR...Sep 2015 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Prostate Cancer Clinical Consortium Clinical Research Site: Targeted Therapies 5b. GRANT NUMBER... therapy resistance/sensitivity, identification of new therapeutic targets through high quality genomic analyses, providing access to the highest quality

25 CFR 1000.338 - What happens to a Tribe's/Consortium's mature contract status if it has retroceded a program that...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false What happens to a Tribe's/Consortium's mature contract...-DETERMINATION AND EDUCATION ACT Retrocession § 1000.338 What happens to a Tribe's/Consortium's mature contract...? Retrocession has no effect on mature contract status, provided that the 3 most recent audits covering...

25 CFR 1000.107 - Must a Tribe/Consortium with a base budget or base budget-eligible program amounts negotiated...

Code of Federal Regulations, 2010 CFR

2010-04-01

... Programs Establishing Self-Governance Base Budgets § 1000.107 Must a Tribe/Consortium with a base budget or... residual amounts? No, if a Tribe/Consortium negotiated amounts before January 16, 2001, it does not need to.... (c) Self-governance Tribes/Consortia are eligible for funding amounts for new or available programs...

25 CFR 1000.18 - May a Consortium member Tribe withdraw from the Consortium and become a member of the applicant...

Code of Federal Regulations, 2010 CFR

2010-04-01

...-governance activities for a member Tribe, that planning activity and report may be used to satisfy the planning requirements for the member Tribe if it applies for self-governance status on its own. (b) Submit... for Participation in Tribal Self-Governance Eligibility § 1000.18 May a Consortium member Tribe...

Northeast Artificial Intelligence Consortium Annual Report - 1988 Parallel Vision. Volume 9

DTIC Science & Technology

1989-10-01

supports the Northeast Aritificial Intelligence Consortium (NAIC). Volume 9 Parallel Vision Report submitted by Christopher M. Brown Randal C. Nelson...NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM ANNUAL REPORT - 1988 Parallel Vision Syracuse University Christopher M. Brown and Randal C. Nelson...Technical Director Directorate of Intelligence & Reconnaissance FOR THE COMMANDER: IGOR G. PLONISCH Directorate of Plans & Programs If your address has

Genesis of an oak-fire science consortium

USGS Publications Warehouse

Grabner, K.W.; Stambaugh, M. C.; Guyette, R.P.; Dey, D. C.; Willson, G.D.; Dey, D. C.; Stambaugh, M. C.; Clark, S.L.; Schweitzer, C. J.

2012-01-01

With respect to fire management and practices, one of the most overlooked regions lies in the middle of the country. In this region there is a critical need for both recognition of fire’s importance and sharing of fire information and expertise. Recently we proposed and were awarded funding by the Joint Fire Science Program to initiate the planning phase for a regional fire consortium. The purpose of the consortium will be to promote the dissemination of fire information across the interior United States and to identify fire information needs of oak-dominated communities such as woodlands, forests, savannas, and barrens. Geographically, the consortium region will cover: 1) the Interior Lowland Plateau Ecoregion in Illinois, Indiana, central Kentucky and Tennessee; 2) the Missouri, Arkansas, and Oklahoma Ozarks; 3) the Ouachita Mountains of Arkansas and Oklahoma; and 4) the Cross Timbers Region in Texas, Oklahoma, and Kansas. This region coincides with the southwestern half of the Central Hardwoods Forest Region. The tasks of this consortium will be to disseminate fire information, connect fire professionals, and efficiently address fire issues within our region. If supported, the success and the future direction of the consortium will be driven by end-users, their input, and involvement.

Remediation of phenol-contaminated soil by a bacterial consortium and Acinetobacter calcoaceticus isolated from an industrial wastewater treatment plant.

PubMed

Cordova-Rosa, S M; Dams, R I; Cordova-Rosa, E V; Radetski, M R; Corrêa, A X R; Radetski, C M

2009-05-15

Time-course performance of a phenol-degrading indigenous bacterial consortium, and of Acinetobacter calcoaceticus var. anitratus, isolated from an industrial coal wastewater treatment plant was evaluated. This bacterial consortium was able to survive in the presence of phenol concentrations as high as 1200mgL(-1) and the consortium was more fast in degrading phenol than a pure culture of the A. calcoaceticus strain. In a batch system, 86% of phenol biodegradation occurred in around 30h at pH 6.0, while at pH 3.0, 95.2% of phenol biodegradation occurred in 8h. A high phenol biodegradation (above 95%) by the mixed culture in a bioreactor was obtained in both continuous and batch systems, but when test was carried out in coke gasification wastewater, no biodegradation was observed after 10 days at pH 9-11 for both pure strain or the isolated consortium. An activated sludge with the same bacterial consortium characterized above was mixed with a textile sludge-contaminated soil with a phenol concentration of 19.48mgkg(-1). After 20 days of bioaugmentation, the remanescent phenol concentration of the sludge-soil matrix was 1.13mgkg(-1).

Bacterial community composition characterization of a lead-contaminated Microcoleus sp. consortium.

PubMed

Giloteaux, Ludovic; Solé, Antoni; Esteve, Isabel; Duran, Robert

2011-08-01

A Microcoleus sp. consortium, obtained from the Ebro delta microbial mat, was maintained under different conditions including uncontaminated, lead-contaminated, and acidic conditions. Terminal restriction fragment length polymorphism and 16S rRNA gene library analyses were performed in order to determine the effect of lead and culture conditions on the Microcoleus sp. consortium. The bacterial composition inside the consortium revealed low diversity and the presence of specific terminal-restriction fragments under lead conditions. 16S rRNA gene library analyses showed that members of the consortium were affiliated to the Alpha, Beta, and Gammaproteobacteria and Cyanobacteria. Sequences closely related to Achromobacter spp., Alcaligenes faecalis, and Thiobacillus species were exclusively found under lead conditions while sequences related to Geitlerinema sp., a cyanobacterium belonging to the Oscillatoriales, were not found in presence of lead. This result showed a strong lead selection of the bacterial members present in the Microcoleus sp. consortium. Several of the 16S rRNA sequences were affiliated to nitrogen-fixing microorganisms including members of the Rhizobiaceae and the Sphingomonadaceae. Additionally, confocal laser scanning microscopy and scanning and transmission electron microscopy showed that under lead-contaminated condition Microcoleus sp. cells were grouped and the number of electrodense intracytoplasmic inclusions was increased.

Biodegradation of low and high molecular weight hydrocarbons in petroleum refinery wastewater by a thermophilic bacterial consortium.

PubMed

Pugazhendi, Arulazhagan; Abbad Wazin, Hadeel; Qari, Huda; Basahi, Jalal Mohammad Al-Badry; Godon, Jean Jacques; Dhavamani, Jeyakumar

2017-10-01

Clean-up of contaminated wastewater remains to be a major challenge in petroleum refinery. Here, we describe the capacity of a bacterial consortium enriched from crude oil drilling site in Al-Khobar, Saudi Arabia, to utilize polycyclic aromatic hydrocarbons (PAHs) as sole carbon source at 60°C. The consortium reduced low molecular weight (LMW; naphthalene, phenanthrene, fluorene and anthracene) and high molecular weight (HMW; pyrene, benzo(e)pyrene and benzo(k)fluoranthene) PAH loads of up to 1.5 g/L with removal efficiencies of 90% and 80% within 10 days. PAH biodegradation was verified by the presence of PAH metabolites and evolution of carbon dioxide (90 ± 3%). Biodegradation led to a reduction of the surface tension to 34 ± 1 mN/m thus suggesting biosurfactant production by the consortium. Phylogenetic analysis of the consortium revealed the presence of the thermophilic PAH degrader Pseudomonas aeruginosa strain CEES1 (KU664514) and Bacillus thermosaudia (KU664515) strain CEES2. The consortium was further found to treat petroleum wastewater in continuous stirred tank reactor with 96 ± 2% chemical oxygen demand removal and complete PAH degradation in 24 days.

Naphthalene degradation by bacterial consortium (DV-AL) developed from Alang-Sosiya ship breaking yard, Gujarat, India.

PubMed

Patel, Vilas; Jain, Siddharth; Madamwar, Datta

2012-03-01

Naphthalene degrading bacterial consortium (DV-AL) was developed by enrichment culture technique from sediment collected from the Alang-Sosiya ship breaking yard, Gujarat, India. The 16S rRNA gene based molecular analyzes revealed that the bacterial consortium (DV-AL) consisted of four strains namely, Achromobacter sp. BAB239, Pseudomonas sp. DV-AL2, Enterobacter sp. BAB240 and Pseudomonas sp. BAB241. Consortium DV-AL was able to degrade 1000 ppm of naphthalene in Bushnell Haas medium (BHM) containing peptone (0.1%) as co-substrate with an initial pH of 8.0 at 37°C under shaking conditions (150 rpm) within 24h. Maximum growth rate and naphthalene degradation rate were found to be 0.0389 h(-1) and 80 mg h(-1), respectively. Consortium DV-AL was able to utilize other aromatic and aliphatic hydrocarbons such as benzene, phenol, carbazole, petroleum oil, diesel fuel, and phenanthrene and 2-methyl naphthalene as sole carbon source. Consortium DV-AL was also efficient to degrade naphthalene in the presence of other pollutants such as petroleum hydrocarbons and heavy metals. Copyright © 2011 Elsevier Ltd. All rights reserved.

Decreased Phototoxic Effects of TiO₂ Nanoparticles in Consortium of Bacterial Isolates from Domestic Waste Water

PubMed Central

Mathur, Ankita; Kumari, Jyoti; Parashar, Abhinav; T., Lavanya; Chandrasekaran, N.; Mukherjee, Amitava

2015-01-01

This study is aimed to explore the toxicity of TiO2 nanoparticles at low concentrations (0.25, 0.50 & 1.00 μg/ml); on five bacterial isolates and their consortium in waste water medium both in dark and UVA conditions. To critically examine the toxic effects of nanoparticles and the response mechanism(s) offered by microbes, several aspects were monitored viz. cell viability, ROS generation, SOD activity, membrane permeability, EPS release and biofilm formation. A dose and time dependent loss in viability was observed for treated isolates and the consortium. At the highest dose, after 24h, oxidative stress was examined which conclusively showed more ROS generation & cell permeability and less SOD activity in single isolates as compared to the consortium. As a defense mechanism, EPS release was enhanced in case of the consortium against the single isolates, and was observed to be dose dependent. Similar results were noticed for biofilm formation, which substantially increased at highest dose of nanoparticle exposure. Concluding, the consortium showed more resistance against the toxic effects of the TiO2 nanoparticles compared to the individual isolates. PMID:26496250

Sulfur formation by steady-state continuous cultures of a sulfoxidizing consortium and Thiobacillus thioparus ATCC 23645.

PubMed

Alcántara, S; Velasco, A; Revah, S

2004-10-01

The elemental sulfur formation by the partial oxidation of thiosulfate by both a sulfoxidizing consortium and by Thiobacillus thioparus ATCC 23645 was studied under aerobic conditions in chemostat. Steady state was attained with essentially total conversion to sulfate when the dissolved oxygen concentration was 5 mgO2 l(-1) and below a dilution rate (D) of 3.0 d(-1)for the consortium and 0.9 d(-1) for T thioparus. The consortium formed elemental sulfur in steady state under oxygen limitation. Fifty percent of the theoretical elemental sulfur yield was obtained with a dissolved oxygen concentration of 0.2 mgO2 l(-1). Growth of T thioparus was negatively affected with a concentration below 1.9 mgO2 l(-1). Consortium yield from batch cultures was 2.1 g(-1) (protein) mol(-1) (thiosulfate), which was comparable with the values obtained in the chemostat at dilution rates of 0.4 d(-1) and 1.2 d(-1). The consortium showed a maximum degradation rate of 0.105 g(thiosulfate) g(-1) (protein) min(-1) and a saturation rate for S2O3(2-) of 1.9 mM.

Support of Gulf of Mexico Hydrate Research Consortium: Activities of Support Establishment of a Sea Floor Monitoring Station Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Robert Woolsey; Thomas McGee; Carol Lutken

2008-05-31

The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research that shared the need for a way to conduct investigations of gas hydrates and their stability zone in the Gulf of Mexico in situ on a more-or-less continuous basis. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (SFO) on the sea floor in the northern Gulf of Mexico, in an area where gas hydrates are known to be present at, or just below, the sea floor and to discover themore » configuration and composition of the subsurface pathways or 'plumbing' through which fluids migrate into and out of the hydrate stability zone (HSZ) to the sediment-water interface. Monitoring changes in this zone and linking them to coincident and perhaps consequent events at the seafloor and within the water column is the eventual goal of the Consortium. This mission includes investigations of the physical, chemical and biological components of the gas hydrate stability zone - the sea-floor/sediment-water interface, the near-sea-floor water column, and the shallow subsurface sediments. The eventual goal is to monitor changes in the hydrate stability zone over time. Establishment of the Consortium succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among those involved in gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative methods and construct necessary instrumentation. Following extensive investigation into candidate sites, Mississippi Canyon 118 (MC118) was chosen by consensus of the Consortium at their fall, 2004, meeting as the site most likely to satisfy all criteria established by the group. Much of the preliminary work preceding the establishment of the site - sensor development and testing, geophysical surveys, and laboratory studies - has been reported in agency documents including the Final Technical Report to DOE covering Cooperative Agreement DEFC26-00NT40920 and Semiannual Progress Reports for this award, DE-FC26-02NT41628. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in MC118 in May of 2005. Follow-up deployments, planned for fall 2005, had to be postponed due to the catastrophic effects of Hurricane Katrina (and later, Rita) on the Gulf Coast. SFO completion, now anticipated for 2009-10, has, therefore, been delayed. Although delays caused scheduling and deployment difficulties, many sensors and instruments were completed during this period. Software has been written that will accommodate the data that the station retrieves, when it begins to be delivered. In addition, new seismic data processing software has been written to treat the peculiar data to be received by the vertical line array (VLA) and additional software has been developed that will address the horizontal line array (HLA) data. These packages have been tested on data from the test deployments of the VLA and on data from other, similar, areas of the Gulf (in the case of the HLA software). During the life of this Cooperative Agreement (CA), the CMRET conducted many cruises. Early in the program these were executed primarily to survey potential sites and test sensors and equipment being developed for the SFO. When MC118 was established as the observatory site, subsequent cruises focused on this location. Beginning in 2005 and continuing to the present, 13 research cruises to MC118 have been conducted by the Consortium. During September, 2006, the Consortium was able to secure 8 days aboard the R/V Seward Johnson with submersible Johnson SeaLink, a critical chapter in the life of the Observatory project as important documentation, tests, recoveries and deployments were accomplished during this trip (log appended). Consortium members have participated materially in a number of additional cruises including several of the NIUST autonomous underwater vehicle (AUV), Eagle Ray. Activities reports summarize cruise activities, including objectives, how they were met or not met, and challenges. Deployment cruises are scheduled for 2009 that are designed to complete installation of the major observatory components.« less

Effects of adding bulking agent, inorganic nutrient and microbial inocula on biopile treatment for oil-field drilling waste.

PubMed

Ma, Jie; Yang, Yongqi; Dai, Xiaoli; Chen, Yetong; Deng, Hanmei; Zhou, Huijun; Guo, Shaohui; Yan, Guangxu

2016-05-01

Contamination from oil-field drilling waste is a worldwide environmental problem. This study investigated the performance of four bench-scale biopiles in treating drilling waste: 1) direct biopile (DW), 2) biopile plus oil-degrading microbial consortium (DW + M), 3) biopile plus microbial consortium and bulking agents (saw dust) (DW + M + BA), 4) biopile plus microbial consortium, bulking agents, and inorganic nutrients (Urea and K2HPO4) (DW + M + BA + N). Ninety days of biopiling removed 41.0%, 44.0%, 55.7% and 87.4% of total petroleum hydrocarbon (TPH) in the pile "DW", "DW + M", "DW + M + BA", and "DW + M + BA + N" respectively. Addition of inorganic nutrient and bulking agents resulted in a 56.9% and 26.6% increase in TPH removal efficiency respectively. In contrast, inoculation of hydrocarbon-degrading microorganisms only slightly enhanced the contaminant removal (increased 7.3%). The biopile with stronger contaminant removal also had higher pile temperature and lower pile pH (e.g., in "DW + M + BA + N"). GC-MS analysis shows that biopiling significantly reduced the total number of detected contaminants and changed the chemical composition. Overall, this study shows that biopiling is an effective remediation technology for drilling waste. Adding inorganic nutrients and bulking agents can significantly improve biopile performance while addition of microbial inocula had minimal positive impacts on contaminant removal. Copyright © 2016 Elsevier Ltd. All rights reserved.

Extending ACTS Operations Through a University-Based Consortium

NASA Technical Reports Server (NTRS)

Bauer, Robert; Krawcyzk, Richard; Irwin, Dennis; Kruse, Hans

2001-01-01

The Advanced Communications Technology Satellite (ACTS) program was slated for decommissioning in October 2000 as was announced at the 6th Ka-band Utilization Conference in May 2000. Quite a celebration was had at that event too centering on the decommissioning of this very successful technology program. With plans in place to move the spacecraft to an orbital graveyard and then shut the system down, NASA was challenged to consider the feasibility of extending operations for education and research purposes provided that an academic organization would be willing to cover operations costs. Continuing operations of the system was determined viable and in the fall of 2000, an announcement was made by NASA to consider extending operations. Plans are now in place to continue the operations of ACTS through a university-based consortium led by Ohio University, Athens, Ohio. Initial plans are for two more years of operations, with options to extend up to a total of four years. This paper will present the change in plans to continue operations of ACTS. A description of the multi-month transition of the spacecraft to its new and final orbital location is provided. With the spacecraft at this new location, an update on its performance is presented as well as estimates of long-term performance. The consortium development will be presented along with its organization, membership, and operations plans for using ACTS.

Degradation of petroleum hydrocarbons and treatment of refinery wastewater under saline condition by a halophilic bacterial consortium enriched from marine environment (Red Sea), Jeddah, Saudi Arabia.

PubMed

Jamal, Mamdoh T; Pugazhendi, Arulazhagan

2018-06-01

A halophilic bacterial consortium was enriched from Red Sea saline water and sediment samples collected from Abhor, Jeddah, Saudi Arabia. The consortium potentially degraded different low (above 90% for phenanthrene and fluorene) and high (69 ± 1.4 and 56 ± 1.8% at 50 and 100 mg/L of pyrene) molecular weight polycyclic aromatic hydrocarbons (PAHs) at different concentrations under saline condition (40 g/L NaCl concentration). The cell hydrophobicity (91° ± 1°) and biosurfactant production (30 mN/m) confirmed potential bacterial cell interaction with PAHs to facilitate biodegradation process. Co-metabolic study with phenanthrene as co-substrate during pyrene degradation recorded 90% degradation in 12 days. The consortium in continuous stirred tank reactor with petroleum refinery wastewater showed complete and 90% degradation of low and high molecular weight PAHs, respectively. The reactor study also revealed 94 ± 1.8% chemical oxygen demand removal by the halophilic consortium under saline condition (40 g/L NaCl concentration). The halophilic bacterial strains present in the consortium were identified as Ochrobactrum halosaudis strain CEES1 (KX377976), Stenotrophomonas maltophilia strain CEES2 (KX377977), Achromobacter xylosoxidans strain CEES3 (KX377978) and Mesorhizobium halosaudis strain CEES4 (KX377979). Thus, the promising halophilic consortium was highly recommended to be employed in petroleum saline wastewater treatment process.

Nonylphenol biodegradation characterizations and bacterial composition analysis of an effective consortium NP-M2.

PubMed

Bai, Naling; Abuduaini, Rexiding; Wang, Sheng; Zhang, Meinan; Zhu, Xufen; Zhao, Yuhua

2017-01-01

Nonylphenol (NP), ubiquitously detected as the degradation product of nonionic surfactants nonylphenol polyethoxylates, has been reported as an endocrine disrupter. However, most pure microorganisms can degrade only limited species of NP with low degradation efficiencies. To establish a microbial consortium that can effectively degrade different forms of NP, in this study, we isolated a facultative microbial consortium NP-M2 and characterized the biodegradation of NP by it. NP-M2 could degrade 75.61% and 89.75% of 1000 mg/L NP within 48 h and 8 days, respectively; an efficiency higher than that of any other consortium or pure microorganism reported so far. The addition of yeast extract promoted the biodegradation more significantly than that of glucose. Moreover, surface-active compounds secreted into the extracellular environment were hypothesized to promote high-efficiency metabolism of NP. The detoxification of NP by this consortium was determined. The degradation pathway was hypothesized to be initiated by oxidization of the benzene ring, followed by step-wise side-chain biodegradation. The bacterial composition of NP-M2 was determined using 16S rDNA library, and the consortium was found to mainly comprise members of the Sphingomonas, Pseudomonas, Alicycliphilus, and Acidovorax genera, with the former two accounting for 86.86% of the consortium. The high degradation efficiency of NP-M2 indicated that it could be a promising candidate for NP bioremediation in situ. Copyright © 2016 Elsevier Ltd. All rights reserved.

25 CFR 1000.316 - May the Tribe/Consortium be reimbursed for actual and reasonable “wind up costs” incurred after...

Code of Federal Regulations, 2010 CFR

2010-04-01

... reasonable âwind up costsâ incurred after the effective date of retrocession? 1000.316 Section 1000.316... Reassumption § 1000.316 May the Tribe/Consortium be reimbursed for actual and reasonable “wind up costs” incurred after the effective date of retrocession? Yes, the Tribe/Consortium may be reimbursed for actual...

77 FR 23754 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-3D PDF Consortium...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-20

... Production Act of 1993--3D PDF Consortium, Inc. Notice is hereby given that, on March 27, 2012, pursuant to.... (``the Act''), 3D PDF Consortium, Inc. (``3D PDF'') has filed written notifications simultaneously with... Corporation, Boulder, CO; Aras Corporation, Andover, MA; Tetra 4D, LLC, Seattle, WA; Tech Soft 3D, Berkeley...

Legacy System Engineering, VPERC Consortium

DTIC Science & Technology

2009-09-01

REPORT Legacy System Engineering, VPERC Consortium, Final Report, University of Utah for Work Ending Joly 15, 2009. 14. ABSTRACT 16. SECURITY...Engineering, VPERC Consortium, Final Report, University of Utah for Work Ending Joly 15, 2009. Report Title ABSTRACT This paper is one of three...Sons, 1995. [3] Turner MJ, Clough RW, Martin HC, Topp LJ. “Stiffness and deflection analysis of complex structures.” Journal of the Aeronautical

77 FR 38831 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-3D PDF Consortium...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-29

... Production Act of 1993--3D PDF Consortium, Inc. Notice is hereby given that, on June 4, 2012, pursuant to.... (``the Act''), 3D PDF Consortium, Inc. (``3D PDF'') has filed written notifications simultaneously with... research project. Membership in this group research project remains open, and 3D PDF intends to file...

The Activities of the European Consortium on Nuclear Data Development and Analysis for Fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fischer, U., E-mail: ulrich.fischer@kit.edu; Avrigeanu, M.; Avrigeanu, V.

This paper presents an overview of the activities of the European Consortium on Nuclear Data Development and Analysis for Fusion. The Consortium combines available European expertise to provide services for the generation, maintenance, and validation of nuclear data evaluations and data files relevant for ITER, IFMIF and DEMO, as well as codes and software tools required for related nuclear calculations.

A Consortium for Research Development (A Consortium for Educational Research Comprised of Seven Private Liberal Arts Colleges). Final Report.

ERIC Educational Resources Information Center

Johnson, Clifton H.

The initial program of the consortium, which comprised Fisk University, Houston-Tillotson College, LeMoyne College, Dillard University, Tougaloo College, Talladega College, and Clark College, and which extended from July 1967 to July 1970 with a total budget of $85,000, was to be basic institutional research that would help the seven predominately…

Prostate Cancer Clinical Consortium Clinical Research Site: Targeted Therapies

DTIC Science & Technology

2017-10-01

AWARD NUMBER: W81XWH-14-2-0159 TITLE: Prostate Cancer Clinical Consortium Clinical Research Site: Targeted Therapies PRINCIPAL INVESTIGATOR...Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for...AND SUBTITLE Prostate Cancer Clinical Consortium Clinical Research Site: Targeted Therapies 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

25 CFR 1000.50 - What must a Tribe/Consortium seeking a planning grant submit in order to meet the planning phase...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false What must a Tribe/Consortium seeking a planning grant submit in order to meet the planning phase requirements? 1000.50 Section 1000.50 Indians OFFICE OF THE...) Planning and Negotiation Grants Advance Planning Grant Funding § 1000.50 What must a Tribe/Consortium...

European Society of Cardiology-Recommended Coronary Artery Disease Consortium Pretest Probability Scores More Accurately Predict Obstructive Coronary Disease and Cardiovascular Events Than the Diamond and Forrester Score: The Partners Registry.

PubMed

Bittencourt, Marcio Sommer; Hulten, Edward; Polonsky, Tamar S; Hoffman, Udo; Nasir, Khurram; Abbara, Suhny; Di Carli, Marcelo; Blankstein, Ron

2016-07-19

The most appropriate score for evaluating the pretest probability of obstructive coronary artery disease (CAD) is unknown. We sought to compare the Diamond-Forrester (DF) score with the 2 CAD consortium scores recently recommended by the European Society of Cardiology. We included 2274 consecutive patients (age, 56±13 years; 57% male) without prior CAD referred for coronary computed tomographic angiography. Computed tomographic angiography findings were used to determine the presence or absence of obstructive CAD (≥50% stenosis). We compared the DF score with the 2 CAD consortium scores with respect to their ability to predict obstructive CAD and the potential implications of these scores on the downstream use of testing for CAD, as recommended by current guidelines. The DF score did not satisfactorily fit the data and resulted in a significant overestimation of the prevalence of obstructive CAD (P<0.001); the CAD consortium basic score had no significant lack of fitness; and the CAD consortium clinical provided adequate goodness of fit (P=0.39). The DF score had a lower discrimination for obstructive CAD, with an area under the receiver-operating characteristics curve of 0.713 versus 0.752 and 0.791 for the CAD consortium models (P<0.001 for both). Consequently, the use of the DF score was associated with fewer individuals being categorized as requiring no additional testing (8.3%) compared with the CAD consortium models (24.6% and 30.0%; P<0.001). The proportion of individuals with a high pretest probability was 18% with the DF and only 1.1% with the CAD consortium scores (P<0.001) CONCLUSIONS: Among contemporary patients referred for noninvasive testing, the DF risk score overestimates the risk of obstructive CAD. On the other hand, the CAD consortium scores offered improved goodness of fit and discrimination; thus, their use could decrease the need for noninvasive or invasive testing while increasing the yield of such tests. © 2016 American Heart Association, Inc.

Ten years of CLIVE (Computer-Aided Learning in Veterinary Education) in the United Kingdom.

PubMed

Dale, Vicki H M; McConnell, Gill; Short, Andrew; Sullivan, Martin

2005-01-01

This paper outlines the work of the CLIVE (Computer-Aided Learning in Veterinary Education) project over a 10-year period, set against the backdrop of changes in education policy and learning technology developments. The consortium of six UK veterinary schools and 14 international Associate Member Schools has been very successful. Sustaining these partnerships requires that the project redefine itself and adapt to cater to the diverse learning needs of today's students and to changing professional and societal needs on an international scale.

Reforming Health Professions Education through a Network of Strategic Multi-Level Partnerships. Scaling Change: Health Professions Pathways (H2P) Consortium

ERIC Educational Resources Information Center

Fox, H. L.

2016-01-01

Several federal grants prioritized the role of community colleges in education and training in recent years, and one of the most substantial investments was the Trade Adjustment Act Community College and Career Training (TAACCCT) program of the United States Department of Labor (DOL). Beginning October 2011, these $2 billion capacity-building…

Automated Algorithm to Detect Changes in Geostationary Satellites Configuration and Cross-Tagging

DTIC Science & Technology

2015-10-18

Color Photometry Catalog (GCPC) and Geo Observations with Latitudinal Diversity Simultaneously ( GOLDS ) data sets are used to simulate configuration...stabilized geostationary satellites in the Geostationary Observations with Latitudinal Diversity Simultaneously ( GOLDS ) and GEO satellite Color...107.3o W. The GOLDS campaign was conducted in two phases, both lead by AFRL’s Space Vehicles Directorate with the participation of a consortium

The Property Tax in New York State: Condition Report Prepared for the Education Finance Research Consortium

ERIC Educational Resources Information Center

Ward, Robert B.; Dadayan, Lucy

2008-01-01

New York's property tax is often criticized as burdensome and inequitable. This report analyzes changes in the property tax from 1993-2006 to assess its impact across regions, property classes and ability to pay. The study examines both statewide trends and variations in trends among local school districts, as well as the role of the School Tax…

A participatory approach to evaluating a national training and institutional change initiative: the BUILD longitudinal evaluation.

PubMed

Davidson, Pamela L; Maccalla, Nicole M G; Afifi, Abdelmonem A; Guerrero, Lourdes; Nakazono, Terry T; Zhong, Shujin; Wallace, Steven P

2017-01-01

The National Institutes of Health (NIH) funds training programs to increase the numbers and skills of scientists who obtain NIH research grants, but few programs have been rigorously evaluated. The sizeable recent NIH investment in developing programs to increase the diversity of the NIH-funded workforce, implemented through the Diversity Program Consortium (DPC), is unusual in that it also funds a Consortium-wide evaluation plan, which spans the activities of the 10 BUilding Infrastructure Leading to Diversity (BUILD) awardees and the National Research Mentoring Network (NRMN). The purpose of this article is to describe the evaluation design and innovations of the BUILD Program on students, faculty, and institutions of the 10 primarily undergraduate BUILD sites. Our approach to this multi-methods quasi-experimental longitudinal evaluation emphasizes stakeholder participation and collaboration. The evaluation plan specifies the major evaluation questions and key short- to long-term outcome measures (or Hallmarks of Success). The Coordination and Evaluation Center (CEC) embarked on a comprehensive evaluation strategy by developing a set of logic models that incorporate the Hallmarks of Success and other outcomes that were collaboratively identified by the DPC. Data were collected from each BUILD site through national surveys from the Higher Education Research Institute at UCLA (HERI), annual followup surveys that align with the HERI instruments, site visits and case studies, program encounter data ("tracker" data), and institutional data. The analytic approach involves comparing changes in Hallmarks (key outcomes) within institutions for biomedical students who participated versus those who did not participate in the BUILD program at each institution, as well as between institution patterns of biomedical students at the BUILD sites, and matched institutions that were not BUILD grantees. Case studies provide insights into the institutionalization of these new programs and help to explain the processes that lead to the observed outcomes. Ultimately, the results of the consortium-wide evaluation will be used to inform national policy in higher education and will provide relevant examples of institutional and educational programmatic changes required to diversify the biomedical workforce in the USA.

GPo1 alkB gene expression for improvement of the degradation of diesel oil by a bacterial consortium.

PubMed

Luo, Qun; He, Ying; Hou, Deng-Yong; Zhang, Jian-Guo; Shen, Xian-Rong

2015-01-01

To facilitate the biodegradation of diesel oil, an oil biodegradation bacterial consortium was constructed. The alkane hydroxylase (alkB) gene of Pseudomonas putida GPo1 was constructed in a pCom8 expression vector, and the pCom8-GPo1 alkB plasmid was transformed into Escherichia coli DH5α. The AlkB protein was expressed by diesel oil induction and detected through SDS-polyacrylamide gel electrophoresis. The culture of the recombinant (pCom8-GPo1 alkB/E. coli DH5α) with the oil biodegradation bacterial consortium increased the degradation ratio of diesel oil at 24 h from 31% to 50%, and the facilitation rates were increased as the proportion of pCom8-GPo1 alkB/E. coli DH5α to the consortium increased. The results suggested that the expression of the GPo1 gene in E. coli DH5α could enhance the function of diesel oil degradation by the bacterial consortium.

Evaluation of thermophilic fungal consortium for organic municipal solid waste composting.

PubMed

Awasthi, Mukesh Kumar; Pandey, Akhilesh Kumar; Khan, Jamaluddin; Bundela, Pushpendra Singh; Wong, Jonathan W C; Selvam, Ammaiyappan

2014-09-01

Influence of fungal consortium and different turning frequency on composting of organic fraction of municipal solid waste (OFMSW) was investigated to produce compost with higher agronomic value. Four piles of OFMSW were prepared: three piles were inoculated with fungal consortium containing 5l each spore suspensions of Trichoderma viride, Aspergillus niger and Aspergillus flavus and with a turning frequency of weekly (Pile 1), twice a week (Pile 2) and daily (Pile 3), while Pile 4 with weekly turning and without fungal inoculation served as control. The fungal consortium with weekly (Pile 1) turning frequency significantly affected temperature, pH, TOC, TKN, C/N ratio and germination index. High degradation of organic matter and early maturity was observed in Pile 1. Results indicate that fungal consortium with weekly turning frequency of open windrows were more cost-effective in comparison with other technologies for efficient composting and yield safe end products. Copyright © 2014 Elsevier Ltd. All rights reserved.

Impact of oil spills on coral reefs can be reduced by bioremediation using probiotic microbiota

PubMed Central

Fragoso ados Santos, Henrique; Duarte, Gustavo Adolpho Santos; Rachid, Caio TavoraCoelho da Costa; Chaloub, Ricardo Moreira; Calderon, Emiliano Nicolas; Marangoni, Laura Fernandes de Barros; Bianchini, Adalto; Nudi, Adriana Haddad; do Carmo, Flávia Lima; van Elsas, Jan Dirk; Rosado, Alexandre Soares; Castro, Clovis Barreira e; Peixoto, Raquel Silva

2015-01-01

Several anthropogenic factors, including contamination by oil spills, constitute a threat to coral reef health. Current methodologies to remediate polluted marine environments are based on the use of chemical dispersants; however, these can be toxic to the coral holobiont. In this study, a probiotic bacterial consortium was produced from the coral Mussismilia harttii and was trained to degrade water-soluble oil fractions (WSFs). Additionally, we assessed the effect of WSFs on the health of M. harttii in tanks and evaluated the bacterial consortium as a bioremediation agent. The consortium was responsible for the highly efficient degradation of petroleum hydrocarbons, and it minimised the effects of WSFs on coral health, as indicated by raised photosynthetic efficiencies. Moreover, the impact of WSFs on the coral microbiome was diminished by the introduced bacterial consortium. Following introduction, the bacterial consortium thus had a dual function, i.e promoting oil WSF degradation and improving coral health with its probiotic features. PMID:26658023

Isolation of a selected microbial consortium capable of degrading methyl parathion and p-nitrophenol from a contaminated soil site.

PubMed

Pino, Nancy J; Dominguez, Maria C; Penuela, Gustavo A

2011-01-01

A bacterial consortium with the ability to degrade methyl parathion and p-nitrophenol, using these compounds as the only carbon source, was obtained by selective enrichment in a medium with methyl parathion. Samples were taken from Moravia, Medellin; an area that is highly contaminated, owing to the fact that it was used as a garbage dump from 1974 to 1982. Acinetobacter sp, Pseudomonas putida, Bacillus sp, Pseudomonas aeruginosa Citrobacter freundii, Stenotrophomonas sp, Flavobacterium sp, Proteus vulgaris, Pseudomonas sp, Acinetobacter sp, Klebsiella sp and Proteus sp were the microorganisms identified within the consortium. In culture, the consortium was able to degrade 150 mg L⁻¹ of methyl-parathion and p-nitrophenol in 120 h, but after adding glucose or peptone to the culture, the time of degradation decreased to 24 h. In soil, the consortium was also able to degrade 150 mg L⁻¹ of methyl parathion in 120 h at different depths and also managed to decrease the toxicity.

GPo1 alkB gene expression for improvement of the degradation of diesel oil by a bacterial consortium

PubMed Central

Luo, Qun; He, Ying; Hou, Deng-Yong; Zhang, Jian-Guo; Shen, Xian-Rong

2015-01-01

To facilitate the biodegradation of diesel oil, an oil biodegradation bacterial consortium was constructed. The alkane hydroxylase (alkB) gene of Pseudomonas putida GPo1 was constructed in a pCom8 expression vector, and the pCom8-GPo1 alkB plasmid was transformed into Escherichia coli DH5α. The AlkB protein was expressed by diesel oil induction and detected through SDS-polyacrylamide gel electrophoresis. The culture of the recombinant (pCom8-GPo1 alkB/E. coli DH5α) with the oil biodegradation bacterial consortium increased the degradation ratio of diesel oil at 24 h from 31% to 50%, and the facilitation rates were increased as the proportion of pCom8-GPo1 alkB/E. coli DH5α to the consortium increased. The results suggested that the expression of the GPo1 gene in E. coli DH5α could enhance the function of diesel oil degradation by the bacterial consortium. PMID:26413044

Advanced nutrient removal from surface water by a consortium of attached microalgae and bacteria: A review.

PubMed

Liu, Junzhuo; Wu, Yonghong; Wu, Chenxi; Muylaert, Koenraad; Vyverman, Wim; Yu, Han-Qing; Muñoz, Raúl; Rittmann, Bruce

2017-10-01

Innovative and cost-effective technologies for advanced nutrient removal from surface water are urgently needed for improving water quality. Conventional biotechnologies, such as ecological floating beds, or constructed wetlands, are not effective in removing nutrients present at low-concentration. However, microalgae-bacteria consortium is promising for advanced nutrient removal from wastewater. Suspended algal-bacterial systems can easily wash out unless the hydraulic retention time is long, attached microalgae-bacteria consortium is more realistic. This critical review summarizes the fundamentals and status of attached microalgae-bacteria consortium for advanced nutrient removal from surface water. Key advantages are the various nutrient removal pathways, reduction of nutrients to very low concentration, and diversified photobioreactor configurations. Challenges include poor identification of functional species, poor control of the community composition, and long start-up times. Future research should focus on the selection and engineering of robust microbial species, mathematical modelling of the composition and functionality of the consortium, and novel photobioreactor configurations. Copyright © 2017 Elsevier Ltd. All rights reserved.

Impact of oil spills on coral reefs can be reduced by bioremediation using probiotic microbiota.

PubMed

Fragoso Ados Santos, Henrique; Duarte, Gustavo Adolpho Santos; Rachid, Caio TavoraCoelho da Costa; Chaloub, Ricardo Moreira; Calderon, Emiliano Nicolas; Marangoni, Laura Fernandes de Barros; Bianchini, Adalto; Nudi, Adriana Haddad; do Carmo, Flávia Lima; van Elsas, Jan Dirk; Rosado, Alexandre Soares; Castro, Clovis Barreira E; Peixoto, Raquel Silva

2015-12-14

Several anthropogenic factors, including contamination by oil spills, constitute a threat to coral reef health. Current methodologies to remediate polluted marine environments are based on the use of chemical dispersants; however, these can be toxic to the coral holobiont. In this study, a probiotic bacterial consortium was produced from the coral Mussismilia harttii and was trained to degrade water-soluble oil fractions (WSFs). Additionally, we assessed the effect of WSFs on the health of M. harttii in tanks and evaluated the bacterial consortium as a bioremediation agent. The consortium was responsible for the highly efficient degradation of petroleum hydrocarbons, and it minimised the effects of WSFs on coral health, as indicated by raised photosynthetic efficiencies. Moreover, the impact of WSFs on the coral microbiome was diminished by the introduced bacterial consortium. Following introduction, the bacterial consortium thus had a dual function, i.e promoting oil WSF degradation and improving coral health with its probiotic features.

11th Annual NIH Pain Consortium Symposium on Advances in Pain Research | Division of Cancer Prevention

Cancer.gov

The NIH Pain Consortium will convene the 11th Annual NIH Pain Consortium Symposium on Advances in Pain Research, featuring keynote speakers and expert panel sessions on Innovative Models and Methods. The first keynote address will be delivered by David J. Clark, MD, PhD, Stanford University entitled “Challenges of Translational Pain Research: What Makes a Good Model?” |

Breaking barriers through collaboration: the example of the Cell Migration Consortium.

PubMed

Horwitz, Alan Rick; Watson, Nikki; Parsons, J Thomas

2002-10-15

Understanding complex integrated biological processes, such as cell migration, requires interdisciplinary approaches. The Cell Migration Consortium, funded by a Large-Scale Collaborative Project Award from the National Institute of General Medical Science, develops and disseminates new technologies, data, reagents, and shared information to a wide audience. The development and operation of this Consortium may provide useful insights for those who plan similarly large-scale, interdisciplinary approaches.

34 CFR 614.4 - Which member of the consortium must act as the lead applicant and fiscal agent?

Code of Federal Regulations, 2010 CFR

2010-07-01

... TEACHERS TO USE TECHNOLOGY § 614.4 Which member of the consortium must act as the lead applicant and fiscal... 34 Education 3 2010-07-01 2010-07-01 false Which member of the consortium must act as the lead applicant and fiscal agent? 614.4 Section 614.4 Education Regulations of the Offices of the Department of...

Northeast Artificial Intelligence Consortium Annual Report. Volume 2. 1988 Discussing, Using, and Recognizing Plans (NLP)

DTIC Science & Technology

1989-10-01

Encontro Portugues de Inteligencia Artificial (EPIA), Oporto, Portugal, September 1985. [15] N. J. Nilsson. Principles Of Artificial Intelligence. Tioga...FI1 F COPY () RADC-TR-89-259, Vol II (of twelve) Interim Report October 1969 AD-A218 154 NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM ANNUAL...7a. NAME OF MONITORING ORGANIZATION Northeast Artificial Of p0ilcabe) Intelligence Consortium (NAIC) Rome_____ Air___ Development____Center

25 CFR 1000.55 - Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this subpart? 1000.55 Section 1000.55 Indians OFFICE OF THE ASSISTANT... Negotiation Grants Advance Planning Grant Funding § 1000.55 Can a Tribe/Consortium appeal within DOI the...

25 CFR 1000.55 - Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this subpart? 1000.55 Section 1000.55 Indians OFFICE OF THE ASSISTANT... Negotiation Grants Advance Planning Grant Funding § 1000.55 Can a Tribe/Consortium appeal within DOI the...

Compatible bacterial mixture, tolerant to desiccation, improves maize plant growth.

PubMed

Molina-Romero, Dalia; Baez, Antonino; Quintero-Hernández, Verónica; Castañeda-Lucio, Miguel; Fuentes-Ramírez, Luis Ernesto; Bustillos-Cristales, María Del Rocío; Rodríguez-Andrade, Osvaldo; Morales-García, Yolanda Elizabeth; Munive, Antonio; Muñoz-Rojas, Jesús

2017-01-01

Plant growth-promoting rhizobacteria (PGPR) increase plant growth and crop productivity. The inoculation of plants with a bacterial mixture (consortium) apparently provides greater benefits to plant growth than inoculation with a single bacterial strain. In the present work, a bacterial consortium was formulated containing four compatible and desiccation-tolerant strains with potential as PGPR. The formulation had one moderately (Pseudomonas putida KT2440) and three highly desiccation-tolerant (Sphingomonas sp. OF178, Azospirillum brasilense Sp7 and Acinetobacter sp. EMM02) strains. The four bacterial strains were able to adhere to seeds and colonize the rhizosphere of plants when applied in both mono-inoculation and multi-inoculation treatments, showing that they can also coexist without antagonistic effects in association with plants. The effects of the bacterial consortium on the growth of blue maize were evaluated. Seeds inoculated with either individual bacterial strains or the bacterial consortium were subjected to two experimental conditions before sowing: normal hydration or desiccation. In general, inoculation with the bacterial consortium increased the shoot and root dry weight, plant height and plant diameter compared to the non-inoculated control or mono-inoculation treatments. The bacterial consortium formulated in this work had greater benefits for blue maize plants even when the inoculated seeds underwent desiccation stress before germination, making this formulation attractive for future field applications.

Compatible bacterial mixture, tolerant to desiccation, improves maize plant growth

PubMed Central

Molina-Romero, Dalia; Baez, Antonino; Quintero-Hernández, Verónica; Castañeda-Lucio, Miguel; Fuentes-Ramírez, Luis Ernesto; Bustillos-Cristales, María del Rocío; Rodríguez-Andrade, Osvaldo; Morales-García, Yolanda Elizabeth; Munive, Antonio

2017-01-01

Plant growth-promoting rhizobacteria (PGPR) increase plant growth and crop productivity. The inoculation of plants with a bacterial mixture (consortium) apparently provides greater benefits to plant growth than inoculation with a single bacterial strain. In the present work, a bacterial consortium was formulated containing four compatible and desiccation-tolerant strains with potential as PGPR. The formulation had one moderately (Pseudomonas putida KT2440) and three highly desiccation-tolerant (Sphingomonas sp. OF178, Azospirillum brasilense Sp7 and Acinetobacter sp. EMM02) strains. The four bacterial strains were able to adhere to seeds and colonize the rhizosphere of plants when applied in both mono-inoculation and multi-inoculation treatments, showing that they can also coexist without antagonistic effects in association with plants. The effects of the bacterial consortium on the growth of blue maize were evaluated. Seeds inoculated with either individual bacterial strains or the bacterial consortium were subjected to two experimental conditions before sowing: normal hydration or desiccation. In general, inoculation with the bacterial consortium increased the shoot and root dry weight, plant height and plant diameter compared to the non-inoculated control or mono-inoculation treatments. The bacterial consortium formulated in this work had greater benefits for blue maize plants even when the inoculated seeds underwent desiccation stress before germination, making this formulation attractive for future field applications. PMID:29117218

Building psychosocial programming in geriatrics fellowships: a consortium model.

PubMed

Adelman, Ronald D; Ansell, Pamela; Breckman, Risa; Snow, Caitlin E; Ehrlich, Amy R; Greene, Michele G; Greenberg, Debra F; Raik, Barrie L; Raymond, Joshua J; Clabby, John F; Fields, Suzanne D; Breznay, Jennifer B

2011-01-01

Geriatric psychosocial problems are prevalent and significantly affect the physical health and overall well-being of older adults. Geriatrics fellows require psychosocial education, and yet to date, geriatrics fellowship programs have not developed a comprehensive geriatric psychosocial curriculum. Fellowship programs in the New York tristate area collaboratively created the New York Metropolitan Area Consortium to Strengthen Psychosocial Programming in Geriatrics Fellowships in 2007 to address this shortfall. The goal of the Consortium is to develop model educational programs for geriatrics fellows that highlight psychosocial issues affecting elder care, share interinstitutional resources, and energize fellowship program directors and faculty. In 2008, 2009, and 2010, Consortium faculty collaboratively designed and implemented a psychosocial educational conference for geriatrics fellows. Cumulative participation at the conferences included 146 geriatrics fellows from 20 academic institutions taught by interdisciplinary Consortium faculty. Formal evaluations from the participants indicated that the conference: a) positively affected fellows' knowledge of, interest in, and comfort with psychosocial issues; b) would have a positive impact on the quality of care provided to older patients; and c) encouraged valuable interactions with fellows and faculty from other institutions. The Consortium, as an educational model for psychosocial learning, has a positive impact on geriatrics fellowship training and may be replicable in other localities.

Surmounting the unique challenges in health disparities education: a multi-institution qualitative study.

PubMed

Carter-Pokras, Olivia; Bereknyei, Sylvia; Lie, Desiree; Braddock, Clarence H

2010-05-01

The National Consortium for Multicultural Education for Health Professionals (Consortium) comprises educators representing 18 US medical schools, funded by the National Institutes of Health. Collective lessons learned from curriculum implementation by principal investigators (PIs) have the potential to guide similar educational endeavors. Describe Consortium PI's self-reported challenges with curricular development, solutions and their new curricular products. Information was collected from PIs over 2 months using a 53-question structured three-part questionnaire. The questionnaire addressed PI demographics, curriculum implementation challenges and solutions, and newly created curricular products. Study participants were 18 Consortium PIs. Descriptive analysis was used for quantitative data. Narrative responses were analyzed and interpreted using qualitative thematic coding. Response rate was 100%. Common barriers and challenges identified by PIs were: finding administrative and leadership support, sustaining the momentum, continued funding, finding curricular space, accessing and engaging communities, and lack of education research methodology skills. Solutions identified included engaging stakeholders, project-sharing across schools, advocacy and active participation in committees and community, and seeking sustainable funding. All Consortium PIs reported new curricular products and extensive dissemination efforts outside their own institutions. The Consortium model has added benefits for curricular innovation and dissemination for cultural competence education to address health disparities. Lessons learned may be applicable to other educational innovation efforts.

Bioremediation and reclamation of soil contaminated with petroleum oil hydrocarbons by exogenously seeded bacterial consortium: a pilot-scale study.

PubMed

Mukherjee, Ashis K; Bordoloi, Naba K

2011-03-01

Spillage of petroleum hydrocarbons causes significant environmental pollution. Bioremediation is an effective process to remediate petroleum oil contaminant from the ecosystem. The aim of the present study was to reclaim a petroleum oil-contaminated soil which was unsuitable for the cultivation of crop plants by using petroleum oil hydrocarbon-degrading microbial consortium. Bacterial consortium consisting of Bacillus subtilis DM-04 and Pseudomonas aeruginosa M and NM strains were seeded to 20% (v/w) petroleum oil-contaminated soil, and bioremediation experiment was carried out for 180 days under laboratory condition. The kinetics of hydrocarbon degradation was analyzed using biochemical and gas chromatographic (GC) techniques. The ecotoxicity of the elutriates obtained from petroleum oil-contaminated soil before and post-treatment with microbial consortium was tested on germination and growth of Bengal gram (Cicer aretinum) and green gram (Phaseolus mungo) seeds. Bacterial consortium showed a significant reduction in total petroleum hydrocarbon level in contaminated soil (76% degradation) as compared to the control soil (3.6% degradation) 180 days post-inoculation. The GC analysis confirmed that bacterial consortium was more effective in degrading the alkane fraction compared to aromatic fraction of crude petroleum oil hydrocarbons in soil. The nitrogen, sulfur, and oxygen compounds fraction was least degraded. The reclaimed soil supported the germination and growth of crop plants (C. aretinum and P. mungo). In contrast, seeds could not be germinated in petroleum oil-contaminated soil. The present study reinforces the application of bacterial consortium rather than individual bacterium for the effective bioremediation and reclamation of soil contaminated with petroleum oil.

The Bridging Advanced Developments for Exceptional Rehabilitation (BADER) Consortium: Reaching in Partnership for Optimal Orthopaedic Rehabilitation Outcomes.

PubMed

Stanhope, Steven J; Wilken, Jason M; Pruziner, Alison L; Dearth, Christopher L; Wyatt, Marilynn; Ziemke, Gregg W; Strickland, Rachel; Milbourne, Suzanne A; Kaufman, Kenton R

2016-11-01

The Bridging Advanced Developments for Exceptional Rehabilitation (BADER) Consortium began in September 2011 as a cooperative agreement with the Department of Defense (DoD) Congressionally Directed Medical Research Programs Peer Reviewed Orthopaedic Research Program. A partnership was formed with DoD Military Treatment Facilities (MTFs), U.S. Department of Veterans Affairs (VA) Centers, the National Institutes of Health (NIH), academia, and industry to rapidly conduct innovative, high-impact, and sustainable clinically relevant research. The BADER Consortium has a unique research capacity-building focus that creates infrastructures and strategically connects and supports research teams to conduct multiteam research initiatives primarily led by MTF and VA investigators.BADER relies on strong partnerships with these agencies to strengthen and support orthopaedic rehabilitation research. Its focus is on the rapid forming and execution of projects focused on obtaining optimal functional outcomes for patients with limb loss and limb injuries. The Consortium is based on an NIH research capacity-building model that comprises essential research support components that are anchored by a set of BADER-funded and initiative-launching studies. Through a partnership with the DoD/VA Extremity Trauma and Amputation Center of Excellence, the BADER Consortium's research initiative-launching program has directly supported the identification and establishment of eight BADER-funded clinical studies. BADER's Clinical Research Core (CRC) staff, who are embedded within each of the MTFs, have supported an additional 37 non-BADER Consortium-funded projects. Additional key research support infrastructures that expedite the process for conducting multisite clinical trials include an omnibus Cooperative Research and Development Agreement and the NIH Clinical Trials Database. A 2015 Defense Health Board report highlighted the Consortium's vital role, stating the research capabilities of the DoD Advanced Rehabilitation Centers are significantly enhanced and facilitated by the BADER Consortium. Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.

Building non-traditional collaborations to innovatively address climate-related scientific and management needs

NASA Astrophysics Data System (ADS)

Bamzai, A.; Mcpherson, R. A.

2014-12-01

The South Central Climate Science Center (SC-CSC) is one of eight regional centers formed by the U.S. Department of the Interior in order to provide decision makers with the science, tools, and information they need to address the impacts of climate variability and change on their areas of responsibility. The SC-CSC is operated through the U.S. Geological Survey, in partnership with a consortium led by the University of Oklahoma that also includes Texas Tech University, Oklahoma State University, Louisiana State University, the Chickasaw Nation, the Choctaw Nation of Oklahoma, and NOAA's Geophysical Fluid Dynamics Lab (GFDL). The SC-CSC is distinct from all other CSCs in that we have strategically included non-traditional collaborators directly within our governing consortium. The SC-CSC is the only CSC to include any Tribal nations amongst our consortium (the Chickasaw Nation and the Choctaw Nation of Oklahoma) and to employ a full-time tribal liaison. As a result and in partnership with Tribes, we are able to identify the unique challenges that the almost 70 federally recognized Tribes within our region face. We also can develop culturally sensitive research projects or outreach efforts that bridge western science and traditional knowledge to address their needs. In addition, the SC-CSC is the only CSC to include another federal institution (GFDL) amongst our consortium membership. GFDL is a world-leader in climate modeling and model interpretation. Partnering GFDL's expertise in the evaluation of climate models and downscaling methods with the SC-CSC's stakeholder-driven approach allows for the generation and dissemination of guidance documents and training to accompany the high quality datasets already in development. This presentation will highlight the success stories and co-benefits of the SC-CSC's collaborations with Tribal nations and with GFDL, as well as include information on how other partners can connect to our ongoing efforts.

Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study.

PubMed

Arambula, Sheryl E; Jima, Dereje; Patisaul, Heather B

2018-03-01

Bisphenol A (BPA) is a widely recognized endocrine disruptor prevalent in many household items. Because experimental and epidemiological data suggest links between prenatal BPA exposure and altered affective behaviors in children, even at levels below the current US FDA No Observed Adverse Effect Level (NOAEL) of 5mg/kg body weight (bw)/day, there is concern that early life exposure may alter neurodevelopment. The current study was conducted as part of the CLARITY-BPA (Consortium Linking Academic and Regulatory Insights on BPA Toxicity) program and examined the full amygdalar transcriptome on postnatal day (PND) 1, with the hypothesis that prenatal BPA exposure would alter the expression of genes and pathways fundamental to sex-specific affective behaviors. NCTR Sprague-Dawley dams were gavaged from gestational day 6 until parturition with BPA (2.5, 25, 250, 2500, or 25000μg/kg bw/day), a reference estrogen (0.05 or 0.5μg ethinyl estradiol (EE 2 )/kg bw/day), or vehicle. PND 1 amygdalae were microdissected and gene expression was assessed with qRT-PCR (all exposure groups) and RNAseq (vehicle, 25 and 250μg BPA, and 0.5μg EE 2 groups only). Our results demonstrate that that prenatal BPA exposure can disrupt the transcriptome of the neonate amygdala, at doses below the FDA NOAEL, in a sex-specific manner and indicate that the female amygdala may be more sensitive to BPA exposure during fetal development. We also provide additional evidence that developmental BPA exposure can interfere with estrogen, oxytocin, and vasopressin signaling pathways in the developing brain and alter signaling pathways critical for synaptic organization and transmission. Copyright © 2017 Elsevier B.V. All rights reserved.

Radiogenomics Consortium (RGC)

Cancer.gov

The Radiogenomics Consortium's hypothesis is that a cancer patient's likelihood of developing toxicity to radiation therapy is influenced by common genetic variations, such as single nucleotide polymorphisms (SNPs).

Legacy Clinical Data from the Mission Connect Mild TBI Translational Research Consortium

DTIC Science & Technology

2017-10-01

mTBI) Translational Research Consortium was to improve the diagnosis and treatment of mTBI. We enrolled a total of 88 mTBI patients and 73 orthopedic ...AWARD NUMBER: W81XWH-16-2-0026 TITLE: Legacy Clinical Data from the Mission Connect Mild TBI Translational Research Consortium PRINCIPAL...Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for

Prostate Cancer Clinical Trials Group: The University of Michigan Site

DTIC Science & Technology

2012-04-01

and fusion-negative strata. UM will be the lead site for this trial with the Univ. of Chicago N01 Phase II consortium as the coordinating center. Ten...sensitive prostate cancer: a University of Chicago Phase II Consortium/Department of Defense Prostate Cancer Clinical Trials Consortium study. JE Ward, T...N01 contract with CTEP (University of Chicago – Early Therapeutics Development with Phase II emphasis group). The Program is committed to creating

ACTS of Education

NASA Technical Reports Server (NTRS)

Bauer, Robert; Krawczyk, Richard; Gargione, Frank; Kruse, Hans; Vrotsos, Pete (Technical Monitor)

2002-01-01

Now in its ninth year of operations, the Advanced Communications Technology Satellite (ACTS) program has continued, although since May 2000 in a new operations arrangement involving a university based consortium, the Ohio Consortium for Advanced Communications Technology (OCACT), While NASA has concluded its experimental intentions of ACTS, the spacecraft's ongoing viability has permitted its further operations to provide educational opportunities to engineering and communications students interested in satellite operations, as well as a Ka-band test bed for commercial interests in utilizing Kaband space communications. The consortium has reached its first year of operations. This generous opportunity by NASA has already resulted in unique educational opportunities for students in obtaining "hands-on" experience, such as, in satellite attitude control. An update is presented on the spacecraft and consortium operations.

Evaluation of Intervention Fidelity in a Multisite Clinical Trial in Persons With Multiple Sclerosis.

PubMed

Morrison, Janet D; Becker, Heather; Stuifbergen, Alexa K

2017-12-01

Careful consideration of intervention fidelity is critical to establishing the validity and reliability of research findings, yet such reports are often lacking in the research literature. It is imperative that intervention fidelity be methodically evaluated and reported to promote the translation of effective interventions into sound evidence-based practice. The purpose of this article is to explore strategies used to promote intervention fidelity, incorporating examples from a multisite clinical trial, that illustrate the National Institutes of Health Behavior Change Consortium's 5 domains for recommended treatment practices: (1) study design, (2) facilitator training, (3) intervention delivery, (4) intervention receipt, and (5) intervention enactment. A multisite randomized clinical trial testing the efficacy of a computer-assisted cognitive rehabilitation intervention for adults with multiple sclerosis is used to illustrate strategies promoting intervention fidelity. Data derived from audiotapes of intervention classes, audits of computer exercises completed by participants, participant class attendance, and goal attainment scaling suggested relatively high fidelity to the intervention protocol. This study illustrates how to report intervention fidelity in the literature guided by best practice strategies, which may serve to promote fidelity monitoring and reporting in future studies.

CIDR

Science.gov Websites

Consortium Developed Arrays Infinium Human Drug Core Array The Illumina nfinium DrugDev Consortium array drug target discovery, validation and treatment response. Detailed Information on Array Infinium Human

Semi-Quantitative Imaging Biomarkers of Knee Osteoarthritis Progression: Data from the FNIH OA Biomarkers Consortium

PubMed Central

Collins, Jamie E.; Losina, Elena; Nevitt, Michael C.; Roemer, Frank W.; Guermazi, Ali; Lynch, John A.; Katz, Jeffrey N.; Kwoh, C. Kent; Kraus, Virginia B.; Hunter, David J.

2017-01-01

Objective To determine the association between changes in semi-quantitative knee MRI biomarkers over 24 months and radiographic and pain progression over 48 months in knees with mild to moderate osteoarthritis. Methods We undertook a nested case-control study as part of the Osteoarthritis Biomarkers Consortium Project. We built multivariable logistic regression models to examine the association between change over 24 months in semi-quantitative MR imaging markers and knee OA radiographic and pain progression. MRIs were read according to the MRI Osteoarthritis Knee Score (MOAKS) scoring system. We focused on changes in cartilage, osteophytes, meniscus, bone marrow lesions, Hoffa-synovitis, and synovitis-effusion. Results The most parsimonious model included changes in cartilage thickness and surface area, synovitis-effusion, Hoffa-synovitis, and meniscal morphology (C-statistic =0.740). Subjects with worsening cartilage thickness in 3+ subregions vs. no worsening had 2.8-fold (95% CI: 1.3 – 5.9) greater odds of being a case while subjects with worsening in cartilage surface area in 3+ subregions vs. no worsening had 2.4-fold (95% CI: 1.3 – 4.4) greater odds of being a case. Having worsening in any region in meniscal morphology was associated with a 2.2-fold (95%CI: 1.3 – 3.8) greater odds of being a case. Worsening synovitis-effusion (OR=2.7) and Hoffa-synovitis (OR=2.0) were also associated with greater odds of being a case. Conclusion Twenty-four-month change in cartilage thickness, cartilage surface area, synovitis-effusion, Hoffa-synovitis, and meniscal morphology were independently associated with OA progression, suggesting that they may serve as efficacy biomarkers in clinical trials of disease modifying interventions for knee OA. PMID:27111771

The Concept of Missing Incidents in Persons with Dementia

PubMed Central

Rowe, Meredeth; Houston, Amy; Molinari, Victor; Bulat, Tatjana; Bowen, Mary Elizabeth; Spring, Heather; Mutolo, Sandra; McKenzie, Barbara

2015-01-01

Behavioral symptoms of dementia often present the greatest challenge for informal caregivers. One behavior, that is a constant concern for caregivers, is the person with dementia leaving a designated area such that their whereabouts become unknown to the caregiver or a missing incident. Based on an extensive literature review and published findings of their own research, members of the International Consortium on Wandering and Missing Incidents constructed a preliminary missing incidents model. Examining the evidence base, specific factors within each category of the model were further described, reviewed and modified until consensus was reached regarding the final model. The model begins to explain in particular the variety of antecedents that are related to missing incidents. The model presented in this paper is designed to be heuristic and may be used to stimulate discussion and the development of effective preventative and response strategies for missing incidents among persons with dementia. PMID:27417817

The Concept of Missing Incidents in Persons with Dementia.

PubMed

Rowe, Meredeth; Houston, Amy; Molinari, Victor; Bulat, Tatjana; Bowen, Mary Elizabeth; Spring, Heather; Mutolo, Sandra; McKenzie, Barbara

2015-11-10

Behavioral symptoms of dementia often present the greatest challenge for informal caregivers. One behavior, that is a constant concern for caregivers, is the person with dementia leaving a designated area such that their whereabouts become unknown to the caregiver or a missing incident. Based on an extensive literature review and published findings of their own research, members of the International Consortium on Wandering and Missing Incidents constructed a preliminary missing incidents model. Examining the evidence base, specific factors within each category of the model were further described, reviewed and modified until consensus was reached regarding the final model. The model begins to explain in particular the variety of antecedents that are related to missing incidents. The model presented in this paper is designed to be heuristic and may be used to stimulate discussion and the development of effective preventative and response strategies for missing incidents among persons with dementia.

C57BL/6N mutation in Cytoplasmic FMR interacting protein 2 regulates cocaine response

PubMed Central

Kumar, Vivek; Kim, Kyungin; Joseph, Chryshanthi; Kourrich, Saïd; Yoo, Seung Hee; Huang, Hung Chung; Vitaterna, Martha H.; de Villena, Fernando Pardo-Manuel; Churchill, Gary; Bonci, Antonello; Takahashi, Joseph S.

2015-01-01

The inbred mouse C57BL/6J is the reference strain for genome sequence and for most behavioral and physiological phenotypes. However the International Knockout Mouse Consortium uses an embryonic stem cell line derived from a related C57BL/6N substrain. We found that C57BL/6N has lower acute and sensitized response to cocaine and methamphetamine. We mapped a single causative locus and identified a non-synonymous mutation of serine to phenylalanine (S968F) in Cytoplasmic FMR interacting protein 2 (Cyfip2) as the causative variant. The S968F mutation destabilizes CYFIP2 and deletion of the C57BL/6N mutant allele leads to acute and sensitized cocaine response phenotypes. We propose CYFIP2 is a key regulator of cocaine response in mammals and present a framework to utilize mouse substrains to discover novel genes and alleles regulating behavior. PMID:24357318

Metagenomic Analysis of a Biphenyl-Degrading Soil Bacterial Consortium Reveals the Metabolic Roles of Specific Populations

PubMed Central

Garrido-Sanz, Daniel; Manzano, Javier; Martín, Marta; Redondo-Nieto, Miguel; Rivilla, Rafael

2018-01-01

Polychlorinated biphenyls (PCBs) are widespread persistent pollutants that cause several adverse health effects. Aerobic bioremediation of PCBs involves the activity of either one bacterial species or a microbial consortium. Using multiple species will enhance the range of PCB congeners co-metabolized since different PCB-degrading microorganisms exhibit different substrate specificity. We have isolated a bacterial consortium by successive enrichment culture using biphenyl (analog of PCBs) as the sole carbon and energy source. This consortium is able to grow on biphenyl, benzoate, and protocatechuate. Whole-community DNA extracted from the consortium was used to analyze biodiversity by Illumina sequencing of a 16S rRNA gene amplicon library and to determine the metagenome by whole-genome shotgun Illumina sequencing. Biodiversity analysis shows that the consortium consists of 24 operational taxonomic units (≥97% identity). The consortium is dominated by strains belonging to the genus Pseudomonas, but also contains betaproteobacteria and Rhodococcus strains. whole-genome shotgun (WGS) analysis resulted in contigs containing 78.3 Mbp of sequenced DNA, representing around 65% of the expected DNA in the consortium. Bioinformatic analysis of this metagenome has identified the genes encoding the enzymes implicated in three pathways for the conversion of biphenyl to benzoate and five pathways from benzoate to tricarboxylic acid (TCA) cycle intermediates, allowing us to model the whole biodegradation network. By genus assignment of coding sequences, we have also been able to determine that the three biphenyl to benzoate pathways are carried out by Rhodococcus strains. In turn, strains belonging to Pseudomonas and Bordetella are the main responsible of three of the benzoate to TCA pathways while the benzoate conversion into TCA cycle intermediates via benzoyl-CoA and the catechol meta-cleavage pathways are carried out by beta proteobacteria belonging to genera such as Achromobacter and Variovorax. We have isolated a Rhodococcus strain WAY2 from the consortium which contains the genes encoding the three biphenyl to benzoate pathways indicating that this strain is responsible for all the biphenyl to benzoate transformations. The presented results show that metagenomic analysis of consortia allows the identification of bacteria active in biodegradation processes and the assignment of specific reactions and pathways to specific bacterial groups. PMID:29497412

On the Need to Establish an International Soil Modeling Consortium

NASA Astrophysics Data System (ADS)

Vereecken, H.; Vanderborght, J.; Schnepf, A.

2014-12-01

Soil is one of the most critical life-supporting compartments of the Biosphere. Soil provides numerous ecosystem services such as a habitat for biodiversity, water and nutrients, as well as producing food, feed, fiber and energy. To feed the rapidly growing world population in 2050, agricultural food production must be doubled using the same land resources footprint. At the same time, soil resources are threatened due to improper management and climate change. Despite the many important functions of soil, many fundamental knowledge gaps remain, regarding the role of soil biota and biodiversity on ecosystem services, the structure and dynamics of soil communities, the interplay between hydrologic and biotic processes, the quantification of soil biogeochemical processes and soil structural processes, the resilience and recovery of soils from stress, as well as the prediction of soil development and the evolution of soils in the landscape, to name a few. Soil models have long played an important role in quantifying and predicting soil processes and related ecosystem services. However, a new generation of soil models based on a whole systems approach comprising all physical, mechanical, chemical and biological processes is now required to address these critical knowledge gaps and thus contribute to the preservation of ecosystem services, improve our understanding of climate-change-feedback processes, bridge basic soil science research and management, and facilitate the communication between science and society. To meet these challenges an international community effort is required, similar to initiatives in systems biology, hydrology, and climate and crop research. Our consortium will bring together modelers and experimental soil scientists at the forefront of new technologies and approaches to characterize soils. By addressing these aims, the consortium will contribute to improve the role of soil modeling as a knowledge dissemination instrument in addressing key global issues and stimulate the development of translational research activities. This presentation will provide a compelling case for this much-needed effort, with a focus on tangible benefits to the scientific and food security communities.

Induced Pluripotent Stem Cells from Patients with Huntington’s Disease Show CAG Repeat Expansion Associated Phenotypes

PubMed Central

Mattis, Virginia B; Svendsen, Soshana P; Ebert, Allison; Svendsen, Clive N; King, Alvin R; Casale, Malcolm; Winokur, Sara T; Batugedara, Gayani; Vawter, Marquis; Donovan, Peter J; Lock, Leslie F; Thompson, Leslie M; Zhu, Yu; Fossale, Elisa; Singh Atwal, Ranjit; Gillis, Tammy; Mysore, Jayalakshmi; Li, Jian-hong; Seong, IhnSik; Shen, Yiping; Chen, Xiaoli; Wheeler, Vanessa C; MacDonald, Marcy E; Gusella, James F; Akimov, Sergey; Arbez, Nicolas; Juopperi, Tarja; Ratovitski, Tamara; Chiang, Jason H; Kim, Woon Roung; Chighladze, Eka; Watkin, Erin; Zhong, Chun; Makri, Georgia; Cole, Robert N; Margolis, Russell L; Song, Hongjun; Ming, Guoli; Ross, Christopher A; Kaye, Julia A; Daub, Aaron; Sharma, Punita; Mason, Amanda R; Finkbeiner, Steven; Yu, Junying; Thomson, James A; Rushton, David; Brazier, Stephen P; Battersby, Alysia A; Redfern, Amanda; Tseng, Hsui-Er; Harrison, Alexander W; Kemp, Paul J; Allen, Nicholas D; Onorati, Marco; Castiglioni, Valentina; Cattaneo, Elena; Arjomand, Jamshid

2013-01-01

Huntington's disease (HD) is an inherited neurodegenerative disorder caused by an expanded stretch of CAG trinucleotide repeats that results in neuronal dysfunction and death. Here, the HD consortium reports the generation and characterization of 14 induced pluripotent stem cell (iPSC) lines from HD patients and controls. Microarray profiling revealed CAG expansion-associated gene expression patterns that distinguish patient lines from controls, and early onset versus late onset HD. Differentiated HD neural cells showed disease associated changes in electrophysiology, metabolism, cell adhesion, and ultimately cell death for lines with both medium and longer CAG repeat expansions. The longer repeat lines were however the most vulnerable to cellular stressors and BDNF withdrawal using a range of assays across consortium laboratories. The HD iPSC collection represents a unique and well-characterized resource to elucidate disease mechanisms in HD and provides a novel human stem cell platform for screening new candidate therapeutics. PMID:22748968

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

PubMed Central

Koscielny, Gautier; Yaikhom, Gagarine; Iyer, Vivek; Meehan, Terrence F.; Morgan, Hugh; Atienza-Herrero, Julian; Blake, Andrew; Chen, Chao-Kung; Easty, Richard; Di Fenza, Armida; Fiegel, Tanja; Grifiths, Mark; Horne, Alan; Karp, Natasha A.; Kurbatova, Natalja; Mason, Jeremy C.; Matthews, Peter; Oakley, Darren J.; Qazi, Asfand; Regnart, Jack; Retha, Ahmad; Santos, Luis A.; Sneddon, Duncan J.; Warren, Jonathan; Westerberg, Henrik; Wilson, Robert J.; Melvin, David G.; Smedley, Damian; Brown, Steve D. M.; Flicek, Paul; Skarnes, William C.; Mallon, Ann-Marie; Parkinson, Helen

2014-01-01

The International Mouse Phenotyping Consortium (IMPC) web portal (http://www.mousephenotype.org) provides the biomedical community with a unified point of access to mutant mice and rich collection of related emerging and existing mouse phenotype data. IMPC mouse clinics worldwide follow rigorous highly structured and standardized protocols for the experimentation, collection and dissemination of data. Dedicated ‘data wranglers’ work with each phenotyping center to collate data and perform quality control of data. An automated statistical analysis pipeline has been developed to identify knockout strains with a significant change in the phenotype parameters. Annotation with biomedical ontologies allows biologists and clinicians to easily find mouse strains with phenotypic traits relevant to their research. Data integration with other resources will provide insights into mammalian gene function and human disease. As phenotype data become available for every gene in the mouse, the IMPC web portal will become an invaluable tool for researchers studying the genetic contributions of genes to human diseases. PMID:24194600

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition.

PubMed

Charbonneau, Mark R; O'Donnell, David; Blanton, Laura V; Totten, Sarah M; Davis, Jasmine C C; Barratt, Michael J; Cheng, Jiye; Guruge, Janaki; Talcott, Michael; Bain, James R; Muehlbauer, Michael J; Ilkayeva, Olga; Wu, Chao; Struckmeyer, Tedd; Barile, Daniela; Mangani, Charles; Jorgensen, Josh; Fan, Yue-mei; Maleta, Kenneth; Dewey, Kathryn G; Ashorn, Per; Newgard, Christopher B; Lebrilla, Carlito; Mills, David A; Gordon, Jeffrey I

2016-02-25

Identifying interventions that more effectively promote healthy growth of children with undernutrition is a pressing global health goal. Analysis of human milk oligosaccharides (HMOs) from 6-month-postpartum mothers in two Malawian birth cohorts revealed that sialylated HMOs are significantly less abundant in those with severely stunted infants. To explore this association, we colonized young germ-free mice with a consortium of bacterial strains cultured from the fecal microbiota of a 6-month-old stunted Malawian infant and fed recipient animals a prototypic Malawian diet with or without purified sialylated bovine milk oligosaccharides (S-BMO). S-BMO produced a microbiota-dependent augmentation of lean body mass gain, changed bone morphology, and altered liver, muscle, and brain metabolism in ways indicative of a greater ability to utilize nutrients for anabolism. These effects were also documented in gnotobiotic piglets using the same consortium and Malawian diet. These preclinical models indicate a causal, microbiota-dependent relationship between S-BMO and growth promotion. Copyright © 2016 Elsevier Inc. All rights reserved.

Improved fermentation performance in an expanded ectopic fermentation system inoculated with thermophilic bacteria.

PubMed

Guo, Hui; Zhu, Changxiong; Geng, Bing; Liu, Xue; Ye, Jing; Tian, Yunlong; Peng, Xiawei

2015-12-01

Previous research showed that ectopic fermentation system (EFS) inoculated with thermophilic bacteria is an excellent alternative for cow wastewater treatment. In this study, the effects of thermophilic bacterial consortium on the efficiency and quality of the fermentation process in EFS were evaluated by measuring physicochemical and environmental factors and the changes in organic matter composition. In parallel, the microbial communities correlated with fermentation performance were identified. Inoculation of EFS with thermophilic bacterial consortium led to higher temperatures, increased wastewater requirements for continuous fermentation, and improved quality of the litters in terms of physicochemical factors, security test, functional group analysis, and bacterial community composition. The relationship between the transformation of organic component and the dominant bacteria species indicated that environmental factors contributed to strain growth, which subsequently promoted the fermentation process. The results highlight the great potential of EFS model for wide application in cow wastewater treatment and re-utilization as bio-fertilizer. Copyright © 2015 Elsevier Ltd. All rights reserved.

Consortium for Materials Development in Space

NASA Technical Reports Server (NTRS)

1999-01-01

During FY99 the Consortium for Materials Development in Space (CMDS) was reorganized around the following guidelines: industry driven, product focus, an industry led advisory council, focus on University of Alabama in Huntsville (UAH) core competencies, linkage to regional investment firms to assist commercialization and to take advantage of space flights. The organizational structure of the CMDS changed considerably during the year. The decision was made to reduce the organization to a Director and an Administrative Assistant. The various research projects, including the employees, were transferred to the appropriate UAH research center or college. In addition, an advisory council was established to provide direction and guidance to the CMDS to ensure a strong commercial focus. The council will (i) review CMDS commercial development plans and provide feedback, (ii) perform an annual evaluation of the Center's progress and present the results of this review to the UAH Vice President for Research, (iii) serve as an avenue of communication between the CMDS and its commercial partners, and (iv) serve as an ambassador and advocate for the CMDS.

Simultaneous biodegradation of three mononitrophenol isomers by a tailor-made microbial consortium immobilized in sequential batch reactors.

PubMed

Fu, H; Zhang, J-J; Xu, Y; Chao, H-J; Zhou, N-Y

2017-03-01

The ortho-nitrophenol (ONP)-utilizing Alcaligenes sp. strain NyZ215, meta-nitrophenol (MNP)-utilizing Cupriavidus necator JMP134 and para-nitrophenol (PNP)-utilizing Pseudomonas sp. strain WBC-3 were assembled as a consortium to degrade three nitrophenol isomers in sequential batch reactors. Pilot test was conducted in flasks to demonstrate that a mixture of three mononitrophenols at 0·5 mol l -1 each could be mineralized by this microbial consortium within 84 h. Interestingly, neither ONP nor MNP was degraded until PNP was almost consumed by strain WBC-3. By immobilizing this consortium into polyurethane cubes, all three mononitrophenols were continuously degraded in lab-scale sequential reactors for six batch cycles over 18 days. Total concentrations of ONP, MMP and PNP that were degraded were 2·8, 1·5 and 2·3 mol l -1 during this time course respectively. Quantitative real-time PCR analysis showed that each member in the microbial consortium was relatively stable during the entire degradation process. This study provides a novel approach to treat polluted water, particularly with a mixture of co-existing isomers. Nitroaromatic compounds are readily spread in the environment and pose great potential toxicity concerns. Here, we report the simultaneous degradation of three isomers of mononitrophenol in a single system by employing a consortium of three bacteria, both in flasks and lab-scale sequential batch reactors. The results demonstrate that simultaneous biodegradation of three mononitrophenol isomers can be achieved by a tailor-made microbial consortium immobilized in sequential batch reactors, providing a pilot study for a novel approach for the bioremediation of mixed pollutants, especially isomers present in wastewater. © 2016 The Society for Applied Microbiology.

The role of bacterial consortium and organic amendment in Cu and Fe isotope fractionation in plants on a polluted mine site.

PubMed

Pérez Rodríguez, Nathalie; Langella, Francesca; Rodushkin, Ilia; Engström, Emma; Kothe, Erika; Alakangas, Lena; Öhlander, Björn

2014-01-01

Copper and iron isotope fractionation by plant uptake and translocation is a matter of current research. As a way to apply the use of Cu and Fe stable isotopes in the phytoremediation of contaminated sites, the effects of organic amendment and microbial addition in a mine-spoiled soil seeded with Helianthus annuus in pot experiments and field trials were studied. Results show that the addition of a microbial consortium of ten bacterial strains has an influence on Cu and Fe isotope fractionation by the uptake and translocation in pot experiments, with an increase in average of 0.99 ‰ for the δ(65)Cu values from soil to roots. In the field trial, the amendment with the addition of bacteria and mycorrhiza as single and double inoculation enriches the leaves in (65)Cu compared to the soil. As a result of the same trial, the δ(56)Fe values in the leaves are lower than those from the bulk soil, although some differences are seen according to the amendment used. Siderophores, possibly released by the bacterial consortium, can be responsible for this change in the Cu and Fe fractionation. The overall isotopic fractionation trend for Cu and Fe does not vary for pot and field experiments with or without bacteria. However, variations in specific metabolic pathways related to metal-organic complexation and weathering can modify particular isotopic signatures.

Standardizing assessment practices of undergraduate medical competencies across medical schools: challenges, opportunities and lessons learned from a consortium of medical schools in Uganda.

PubMed

Mubuuke, Aloysius Gonzaga; Mwesigwa, Catherine; Maling, Samuel; Rukundo, Godfrey; Kagawa, Mike; Kitara, David Lagoro; Kiguli, Sarah

2014-01-01

Health professions education is gradually moving away from the more traditional approaches to new innovative ways of training aimed at producing professionals with the necessary competencies to address the community health needs. In response to these emerging trends, Medical Education for Equitable Services to All Ugandans (MESAU), a consortium of Ugandan medical schools developed key competencies desirable of graduates and successfully implemented Competency Based Education (CBE) for undergraduate medical students. To examine the current situation and establish whether assessment methods of the competencies are standardized across MESAU schools as well as establish the challenges, opportunities and lessons learned from the MESAU consortium. It was a cross-sectional descriptive study involving faculty of the medical schools in Uganda. Data was collected using focus group discussions and document reviews. Findings were presented in form of themes. Although the MESAU schools have implemented the developed competencies within their curricular, the assessment methods are still not standardized with each institution having its own assessment procedures. Lack of knowledge and skills regarding assessment of the competencies was evident amongst the faculty. The fear for change amongst lecturers was also noted as a major challenge. However, the institutional collaboration created while developing competencies was identified as key strength. Findings demonstrated that despite having common competencies, there is no standardized assessment blue print applicable to all MESAU schools. Continued collaboration and faculty development in assessment is strongly recommended.

Standardizing assessment practices of undergraduate medical competencies across medical schools: challenges, opportunities and lessons learned from a consortium of medical schools in Uganda

PubMed Central

Mubuuke, Aloysius Gonzaga; Mwesigwa, Catherine; Maling, Samuel; Rukundo, Godfrey; Kagawa, Mike; Kitara, David Lagoro; Kiguli, Sarah

2014-01-01

Introduction Health professions education is gradually moving away from the more traditional approaches to new innovative ways of training aimed at producing professionals with the necessary competencies to address the community health needs. In response to these emerging trends, Medical Education for Equitable Services to All Ugandans (MESAU), a consortium of Ugandan medical schools developed key competencies desirable of graduates and successfully implemented Competency Based Education (CBE) for undergraduate medical students. Objectives To examine the current situation and establish whether assessment methods of the competencies are standardized across MESAU schools as well as establish the challenges, opportunities and lessons learned from the MESAU consortium. Methods It was a cross-sectional descriptive study involving faculty of the medical schools in Uganda. Data was collected using focus group discussions and document reviews. Findings were presented in form of themes. Results Although the MESAU schools have implemented the developed competencies within their curricular, the assessment methods are still not standardized with each institution having its own assessment procedures. Lack of knowledge and skills regarding assessment of the competencies was evident amongst the faculty. The fear for change amongst lecturers was also noted as a major challenge. However, the institutional collaboration created while developing competencies was identified as key strength. Conclusion Findings demonstrated that despite having common competencies, there is no standardized assessment blue print applicable to all MESAU schools. Continued collaboration and faculty development in assessment is strongly recommended. PMID:25995778

Needs-driven versus market-driven pharmaceutical innovation: the consortium for the development of a new medicine against malaria in Brazil.

PubMed

Kameda, Koichi

2014-08-01

The prevailing model for encouraging innovation based on patents and market-oriented raises at least two economic and ethical issues: it imposes barriers on individuals and developing countries governments' access to medicines by defining prices that do not match their income, and the unavailability of new or appropriate products to address the health problems of these populations. In the last decade, this scenario has undergone some changes due to the emergence of new actors, the contribution of aid resources, the introduction to the market of new products against neglected diseases, the development of new governmental healthcare policies and research programs, etc. One example of such initiatives is the Fixed-Dose Artesunate Combination Therapy (FACT) project consortium, which brought together institutions with different natures from both the North and the South, for the development of two antimalarial fixed-dose combinations recommended by the WHO - artesunate-amodiaquine (ASAQ) and artesunate-mefloquine (ASMQ). This paper proposes to describe and analyze the ASMQ consortium, which is the result of a new pharmaceutical development approach, based on a different paradigm - needs-driven instead of market-driven -, collaborative, with strategic participation of institutions from the South, funded by alternative resources (public and philanthropic). Thus, it represents an interesting object of study for bioethical debates on intellectual property and innovation, and its analysis is justified in light of the current debate on ways of stimulating needs-driven pharmaceutical innovation. © 2014 John Wiley & Sons Ltd.

Stability of the rhizosphere and endophytic bacterial communities associated with Arabidopsis thaliana (L.) Heynh under impact of cosmic factors

NASA Astrophysics Data System (ADS)

Kordium, V. A.; Adamchuk-Chala, N. I.; Moshinec, H. V.

The orbital experiment will involve a growing of Arabidopsis plant seed to seed in the presence of a plant probiotic bacteria consortium introduced into the system The purpose of experiment is to characterize microbial community associated with Arabidopsis thaliana and determine how consortium of introduced bacteria along with the endemic plant-associated bacteria influences the plant development reproductive system and seed formation in spaceflight conditions The first study will be an examination of the survival of model bacteria in on the inoculated plant The second complex study is to examine the plant traits in particular the ultrastructure of root statocytes in order to determine whether the plant development proceeds normally under microgravity conditions on background of introduced bacteria and to assess the structural changes occurring in the cotyledons generative organs and seeds The third set of observations will concern studies of the structure of microbial community associated with Arabidopsis plants with traditional and molecular tools The fourth part of the work will be an examination of mobile genetic elements that can play a role in adaptation of bacteria to the spaceflight conditions however they may affect the stability of bacterial endo- and rhizosphere communities The final part of the proposal initiates the study of possible risk of the bacterial consortium use for a plant inoculation in spaceflight conditions An evaluation of this risk will be performed via examination of expression of the Klebsiella

Environmental microbiology as a mosaic of explored ecosystems and issues.

PubMed

Faure, Denis; Bonin, Patricia; Duran, Robert

2015-09-01

Microbes are phylogenetically (Archaea, Bacteria, Eukarya, and viruses) and functionally diverse. They colonize highly varied environments and rapidly respond to and evolve as a response to local and global environmental changes, including those induced by pollutants resulting from human activities. This review exemplifies the Microbial Ecology EC2CO consortium's efforts to explore the biology, ecology, diversity, and roles of microbes in aquatic and continental ecosystems.

Mission Connect Mild TBI Translational Research Consortium

DTIC Science & Technology

2010-08-31

symptoms are known to be associated with the study drug, atorvastatin , and they are listed in the Informed Consent document. In this second year of the...confirm that atorvastatin (see note below) given during the acute phase of MTBI has no adverse effects in patients with MTBI NOTE: Due to an...FDA hold on all human studies involving erythropoietin, the neuroprotective agent for this phase II clinical trial was changed to atorvastatin

Valuing and Maintaining Independent Research with Private Sector Funding

NASA Astrophysics Data System (ADS)

Prinn, R. G.

2016-12-01

Industries have been funding important research programs in the Geosciences at universities for decades. This support has proven to be beneficial to both universities and the private sector. It is of course important that the independence of the researchers in this relationship is maintained. The relationship usually involves a common interest in understanding and solving a particular problem. Some common keys to maintaining independence have been transparency about the relationship, control of the research agenda by the researchers, and no censorship of publications. In addressing this topic, I will draw upon my experience in two programs that have been funded by industry as well as federal agencies. The 25-year-old Joint Program on the Science and Policy of Global Change uses coupled earth system and economic models to quantify risks of climate change and assess affordable ways to evolve to low to zero emission energy in the future, and is funded by DOE and other federal agencies plus a large consortium of industries (globalchange.mit.edu). And the 38-year-old AGAGE global network that measures, and estimates emissions and lifetimes, of greenhouse and ozone-depleting gases, and is funded by NASA but was also supported in its first 6 years by a consortium of CFC manufacturing companies (agage.mit.edu).

Massachusetts Institute of Technology Consortium Agreement

DTIC Science & Technology

1999-03-01

In this, our second progress report of the Phase Two Home Automation and Healthcare Consortium at the Brit and Alex d’Arbeloff Laboratory for...Covered here are the diverse fields of home automation and healthcare research, ranging from human modeling, patient monitoring, and diagnosis to new...sensors and actuators, physical aids, human-machine interface and home automation infrastructure. These results will be presented at the upcoming General Assembly of the Consortium held on October 27-October 30, 1998 at MIT.

Development of a consortium for water security and safety: Planning for an early warning system

USGS Publications Warehouse

Clark, R.M.; Adam, N.R.; Atluri, V.; Halem, M.; Vowinkel, E.F.; ,

2004-01-01

The events of September 11, 2001 have raised concerns over the safety and security of the Nation's critical infrastructure including water and waste water systems. In June 2002, the U.S. EPA's Region II Office (New York City), in response to concerns over water security, in collaboration with Rutgers University agreed to establish a Regional Drinking Water Security and Safety Consortium (RDWSSC). Members of the consortium include: Rutgers University's Center for Information Management, Integration and Connectivity (CIMIC), American Water (AW), the Passaic Valley Water Commission (PVWC), the North Jersey District Water Supply Commission (NJDWSC), the N.J. Department of Environmental Protection, the U.S. Geological Survey (USGS), and the U.S. Environmental Protection Agencies, Region II Office. In December of 2002 the consortium members signed a memorandum of understanding (MOU) to pursue activities to enhance regional water security. Development of an early warning system for source and distributed water was identified as being of primary importance by the consortium. In this context, an early warning system (EWS) is an integrated system of monitoring stations located at strategic points in a water utilities source waters or in its distribution system, designed to warn against contaminants that might threaten the health and welfare of drinking water consumers. This paper will discuss the consortium's progress in achieving these important objectives.

Decolorization of adsorbed textile dyes by developed consortium of Pseudomonas sp. SUK1 and Aspergillus ochraceus NCIM-1146 under solid state fermentation.

PubMed

Kadam, Avinash A; Telke, Amar A; Jagtap, Sujit S; Govindwar, Sanjay P

2011-05-15

The objective of this study was to develop consortium using Pseudomonas sp. SUK1 and Aspergillus ochraceus NCIM-1146 to decolorize adsorbed dyes from textile effluent wastewater under solid state fermentation. Among various agricultural wastes rice bran showed dye adsorption up to 90, 62 and 80% from textile dye reactive navy blue HE2R (RNB HE2R) solution, mixture of textile dyes and textile industry wastewater, respectively. Pseudomonas sp. SUK1 and A. ochraceus NCIM-1146 showed 62 and 38% decolorization of RNB HE2R adsorbed on rice bran in 24h under solid state fermentation. However, the consortium of Pseudomonas sp. SUK1 and A. ochraceus NCIM-1146 (consortium-PA) showed 80% decolorization in 24h. The consortium-PA showed effective ADMI removal ratio of adsorbed dyes from textile industry wastewater (77%), mixture of textile dyes (82%) and chemical precipitate of textile dye effluent (CPTDE) (86%). Secretion of extracellular enzymes such as laccase, azoreductase, tyrosinase and NADH-DCIP reductase and their significant induction in the presence of adsorbed dye suggests their role in the decolorization of RNB HE2R. GCMS and HPLC analysis of product suggests the different fates of biodegradation of RNB HE2R when used Pseudomonas sp. SUK1, A. ochraceus NCIM-1146 and consortium PA. Copyright © 2011 Elsevier B.V. All rights reserved.

Surmounting the Unique Challenges in Health Disparities Education: A Multi-Institution Qualitative Study

PubMed Central

Bereknyei, Sylvia; Lie, Desiree; Braddock, Clarence H.

2010-01-01

Background The National Consortium for Multicultural Education for Health Professionals (Consortium) comprises educators representing 18 US medical schools, funded by the National Institutes of Health. Collective lessons learned from curriculum implementation by principal investigators (PIs) have the potential to guide similar educational endeavors. Objective Describe Consortium PI’s self-reported challenges with curricular development, solutions and their new curricular products. Methods Information was collected from PIs over 2 months using a 53-question structured three-part questionnaire. The questionnaire addressed PI demographics, curriculum implementation challenges and solutions, and newly created curricular products. Study participants were 18 Consortium PIs. Descriptive analysis was used for quantitative data. Narrative responses were analyzed and interpreted using qualitative thematic coding. Results Response rate was 100%. Common barriers and challenges identified by PIs were: finding administrative and leadership support, sustaining the momentum, continued funding, finding curricular space, accessing and engaging communities, and lack of education research methodology skills. Solutions identified included engaging stakeholders, project-sharing across schools, advocacy and active participation in committees and community, and seeking sustainable funding. All Consortium PIs reported new curricular products and extensive dissemination efforts outside their own institutions. Conclusion The Consortium model has added benefits for curricular innovation and dissemination for cultural competence education to address health disparities. Lessons learned may be applicable to other educational innovation efforts. PMID:20352503

Mineralization and Detoxification of the Carcinogenic Azo Dye Congo Red and Real Textile Effluent by a Polyurethane Foam Immobilized Microbial Consortium in an Upflow Column Bioreactor.

PubMed

Lade, Harshad; Govindwar, Sanjay; Paul, Diby

2015-06-16

A microbial consortium that is able to grow in wheat bran (WB) medium and decolorize the carcinogenic azo dye Congo red (CR) was developed. The microbial consortium was immobilized on polyurethane foam (PUF). Batch studies with the PUF-immobilized microbial consortium showed complete removal of CR dye (100 mg·L-1) within 12 h at pH 7.5 and temperature 30 ± 0.2 °C under microaerophilic conditions. Additionally, 92% American Dye Manufactureing Institute (ADMI) removal for real textile effluent (RTE, 50%) was also observed within 20 h under the same conditions. An upflow column reactor containing PUF-immobilized microbial consortium achieved 99% CR dye (100 mg·L-1) and 92% ADMI removal of RTE (50%) at 35 and 20 mL·h-l flow rates, respectively. Consequent reduction in TOC (83 and 79%), COD (85 and 83%) and BOD (79 and 78%) of CR dye and RTE were also observed, which suggested mineralization. The decolorization process was traced to be enzymatic as treated samples showed significant induction of oxidoreductive enzymes. The proposed biodegradation pathway of the dye revealed the formation of lower molecular weight compounds. Toxicity studies with a plant bioassay and acute tests indicated that the PUF-immobilized microbial consortium favors detoxification of the dye and textile effluents.

Mineralization and Detoxification of the Carcinogenic Azo Dye Congo Red and Real Textile Effluent by a Polyurethane Foam Immobilized Microbial Consortium in an Upflow Column Bioreactor

PubMed Central

Lade, Harshad; Govindwar, Sanjay; Paul, Diby

2015-01-01

A microbial consortium that is able to grow in wheat bran (WB) medium and decolorize the carcinogenic azo dye Congo red (CR) was developed. The microbial consortium was immobilized on polyurethane foam (PUF). Batch studies with the PUF-immobilized microbial consortium showed complete removal of CR dye (100 mg·L−1) within 12 h at pH 7.5 and temperature 30 ± 0.2 °C under microaerophilic conditions. Additionally, 92% American Dye Manufactureing Institute (ADMI) removal for real textile effluent (RTE, 50%) was also observed within 20 h under the same conditions. An upflow column reactor containing PUF-immobilized microbial consortium achieved 99% CR dye (100 mg·L−1) and 92% ADMI removal of RTE (50%) at 35 and 20 mL·h−l flow rates, respectively. Consequent reduction in TOC (83 and 79%), COD (85 and 83%) and BOD (79 and 78%) of CR dye and RTE were also observed, which suggested mineralization. The decolorization process was traced to be enzymatic as treated samples showed significant induction of oxidoreductive enzymes. The proposed biodegradation pathway of the dye revealed the formation of lower molecular weight compounds. Toxicity studies with a plant bioassay and acute tests indicated that the PUF-immobilized microbial consortium favors detoxification of the dye and textile effluents. PMID:26086710

NCI Cohort Consortium Membership

Cancer.gov

The NCI Cohort Consortium membership is international and includes investigators responsible for more than 40 high-quality cohorts who are studying large and diverse populations in more than 15 different countries.

Decolorization and biogas production by an anaerobic consortium: effect of different azo dyes and quinoid redox mediators.

PubMed

Alvarez, L H; Valdez-Espinoza, R; García-Reyes, R B; Olivo-Alanis, D; Garza-González, M T; Meza-Escalante, E R; Gortáres-Moroyoqui, P

2015-01-01

The inhibitory effect of azo dyes and quinoid compounds on an anaerobic consortium was evaluated during a decolorization process and biogas production. In addition, the impact of quinoid compounds such as lawsone (LAW) and anthraquinone-2,6-disulfonate (AQDS) on the rate of decolorization of Direct Blue 71 (DB71) was assessed. The anaerobic consortium was not completely inhibited under all tested dye concentrations (0.1-2 mmol l(-1)), evidenced by an active decolorization process and biogas production. The presence of quinoid compounds at different concentrations (4, 8, and 12 mmol l(-1)) also inhibited biogas production compared to the control incubated without the quinoid compounds. In summary, the anaerobic consortium was affected to a greater extent by increasing the quantity of azo dyes or quinoid compounds. Nevertheless, at a lower concentration (1 mmol l(-1)) of quinoid compounds, the anaerobic consortium effectively decolorized 2 mmol l(-1) of DB71, increasing up to 5.2- and 20.4-fold the rate of decolorization with AQDS and LAW, respectively, compared to the control lacking quinoid compounds.

National Institute on Alcohol Abuse and Alcoholism and the study of fetal alcohol spectrum disorders. The International Consortium.

PubMed

Calhoun, Faye; Attilia, Maria Luisa; Spagnolo, Primavera Alessandra; Rotondo, Claudia; Mancinelli, Rosanna; Ceccanti, Mauro

2006-01-01

Fetal alcohol syndrome (FAS) is a large and rapidly increasing public health problem worldwide. Aside the full-blown FAS, multiple terms are used to describe the continuum of effects that result from prenatal exposure to alcohol, including the whole fetal alcohol spectrum disorders (FASD). The revised Institute of Medicine (IOM) Diagnostic Classification System and the diagnostic criteria for FAS and FASD are reported, as well as the formation of the four-state FAS International Consortium and its aims, as the development of an information base that systematizes data collection that helps to determine at-high-risk populations, and to implement and test a scientific-based prevention/intervention model for at risk women. The Consortium was further enlarged, with the inclusion of some more states (including Italy), leading to the formation of the International Consortium for the Investigation of FASD. The objectives of the Consortium are reported, as well as its previous activities, the South Africa and Italy Projects (active case ascertainment initiatives), and its future activities.

Consortia for Engineering, Science and Technology Libraries in India: A Case Study of INDEST Consortium

NASA Astrophysics Data System (ADS)

Pathak, S. K.; Deshpande, N. J.

2007-10-01

The present scenario of the INDEST Consortium among engineering, science and technology (including astronomy and astrophysics) libraries in India is discussed. The Indian National Digital Library in Engineering Sciences & Technology (INDEST) Consortium is a major initiative of the Ministry of Human Resource Development, Government of India. The INDEST Consortium provides access to 16 full text e-resources and 7 bibliographic databases for 166 institutions as members who are taking advantage of cost effective access to premier resources in engineering, science and technology, including astronomy and astrophysics. Member institutions can access over 6500 e-journals from 1092 publishers. Out of these, over 150 e-journals are exclusively for the astronomy and physics community. The current study also presents a comparative analysis of the key features of nine major services, viz. ACM Digital Library, ASCE Journals, ASME Journals, EBSCO Databases (Business Source Premier), Elsevier's Science Direct, Emerald Full Text, IEEE/IEE Electronic Library Online (IEL), ProQuest ABI/INFORM and Springer Verlag's Link. In this paper, the limitations of this consortium are also discussed.

Rubber gloves biodegradation by a consortium, mixed culture and pure culture isolated from soil samples.

PubMed

Nawong, Chairat; Umsakul, Kamontam; Sermwittayawong, Natthawan

2018-02-03

An increasing production of natural rubber (NR) products has led to major challenges in waste management. In this study, the degradation of rubber latex gloves in a mineral salt medium (MSM) using a bacterial consortium, a mixed culture of the selected bacteria and a pure culture were studied. The highest 18% weight loss of the rubber gloves were detected after incubated with the mixed culture. The increased viable cell counts over incubation time indicated that cells used rubber gloves as sole carbon source leading to the degradation of the polymer. The growth behavior of NR-degrading bacteria on the latex gloves surface was investigated using the scanning electron microscope (SEM). The occurrence of the aldehyde groups in the degradation products was observed by Fourier Transform Infrared Spectroscopy analysis. Rhodococcus pyridinivorans strain F5 gave the highest weight loss of rubber gloves among the isolated strain and posses latex clearing protein encoded by lcp gene. The mixed culture of the selected strains showed the potential in degrading rubber within 30 days and is considered to be used efficiently for rubber product degradation. This is the first report to demonstrate a strong ability to degrade rubber by Rhodococcus pyridinivorans. Copyright © 2018. Published by Elsevier Editora Ltda.

NCI Pediatric Preclinical Testing Consortium

Cancer.gov

NCI has awarded grants to five research teams to participate in its Pediatric Preclinical Testing Consortium, which is intended to help to prioritize which agents to pursue in pediatric clinical trials.

The ISPRS Student Consortium: From launch to tenth anniversary

NASA Astrophysics Data System (ADS)

Kanjir, U.; Detchev, I.; Reyes, S. R.; Akkartal Aktas, A.; Lo, C. Y.; Miyazaki, H.

2014-04-01

The ISPRS Student Consortium is an international organization for students and young professionals in the fields of photogrammetry, remote sensing, and the geospatial information sciences. Since its start ten years ago, the number of members of the Student Consortium has been steadily growing, now reaching close to 1000. Its increased popularity, especially in recent years, is mainly due to the organization's worldwide involvement in student matters. The Student Consortium has helped organize numerous summer schools, youth forums, and student technical sessions at ISPRS sponsored conferences. In addition, the organization publishes a newsletter, and hosts several social media outlets in order to keep its global membership up-to-date on a regular basis. This paper will describe the structure of the organization, and it will give some example of its past student related activities.

Remote sensing and GIS technology in the Global Land Ice Measurements from Space (GLIMS) Project

USGS Publications Warehouse

Raup, B.; Kääb, Andreas; Kargel, J.S.; Bishop, M.P.; Hamilton, G.; Lee, E.; Paul, F.; Rau, F.; Soltesz, D.; Khalsa, S.J.S.; Beedle, M.; Helm, C.

2007-01-01

Global Land Ice Measurements from Space (GLIMS) is an international consortium established to acquire satellite images of the world's glaciers, analyze them for glacier extent and changes, and to assess these change data in terms of forcings. The consortium is organized into a system of Regional Centers, each of which is responsible for glaciers in their region of expertise. Specialized needs for mapping glaciers in a distributed analysis environment require considerable work developing software tools: terrain classification emphasizing snow, ice, water, and admixtures of ice with rock debris; change detection and analysis; visualization of images and derived data; interpretation and archival of derived data; and analysis to ensure consistency of results from different Regional Centers. A global glacier database has been designed and implemented at the National Snow and Ice Data Center (Boulder, CO); parameters have been expanded from those of the World Glacier Inventory (WGI), and the database has been structured to be compatible with (and to incorporate) WGI data. The project as a whole was originated, and has been coordinated by, the US Geological Survey (Flagstaff, AZ), which has also led the development of an interactive tool for automated analysis and manual editing of glacier images and derived data (GLIMSView). This article addresses remote sensing and Geographic Information Science techniques developed within the framework of GLIMS in order to fulfill the goals of this distributed project. Sample applications illustrating the developed techniques are also shown. ?? 2006 Elsevier Ltd. All rights reserved.

COnsortium of METabolomics Studies (COMETS)

Cancer.gov

The COnsortium of METabolomics Studies (COMETS) is an extramural-intramural partnership that promotes collaboration among prospective cohort studies that follow participants for a range of outcomes and perform metabolomic profiling of individuals.

The climate continuum revisited

NASA Astrophysics Data System (ADS)

Emile-Geay, J.; Wang, J.; Partin, J. W.

2015-12-01

A grand challenge of climate science is to quantify the extent of natural variability on adaptation-relevant timescales (10-100y). Since the instrumental record is too short to adequately estimate the spectra of climate measures, this information must be derived from paleoclimate proxies, which may harbor a many-to-one, non-linear (e.g. thresholded) and non-stationary relationship to climate. In this talk, I will touch upon the estimation of climate scaling behavior from climate proxies. Two case studies will be presented: an investigation of scaling behavior in a reconstruction of global surface temperature using state-of- the-art data [PAGES2K Consortium, in prep] and methods [Guillot et al., 2015]. Estimating the scaling exponent β in spectra derived from this reconstruction, we find that 0 < β < 1 in most regions, suggesting long-term memory. Overall, the reconstruction-based spectra are steeper than the ones based on an instrumental dataset [HadCRUT4.2, Morice et al., 2012], and those estimated from PMIP3/CMIP5 models, suggesting the climate system is more energetic at multidecadal to centennial timescales than can be inferred from the short instrumental record or from the models developed to reproduce it [Laepple and Huybers, 2014]. an investigation of scaling behavior in speleothems records of tropical hydroclimate. We will make use of recent advances in proxy system modeling [Dee et al., 2015] and investigate how various aspects of the speleothem system (karst dynamics, age uncertainties) may conspire to bias the estimate of scaling behavior from speleothem timeseries. The results suggest that ignoring such complications leads to erroneous inferences about hydroclimate scaling. References Dee, S. G., J. Emile-Geay, M. N. Evans, Allam, A., D. M. Thompson, and E. J. Steig (2015), J. Adv. Mod. Earth Sys., 07, doi:10.1002/2015MS000447. Guillot, D., B. Rajaratnam, and J. Emile-Geay (2015), Ann. Applied. Statist., pp. 324-352, doi:10.1214/14-AOAS794. Laepple, T., and P. Huybers (2014), PNAS, doi: 10.1073/pnas.1412077111. Morice, C. P., J. J. Kennedy, N. A. Rayner, and P. D. Jones (2012), JGR: Atmospheres, 117(D8), doi:10.1029/2011JD017187. PAGES2K Consortium (in prep), A global multiproxy database for temperature reconstructions of the Common Era, Scientific Data.

International Cancer Proteogenome Consortium | Office of Cancer Clinical Proteomics Research

Cancer.gov

The International Cancer Proteogenome Consortium (ICPC), is a voluntary scientific organization that provides a forum for collaboration among some of the world's leading cancer and proteogenomic research centers.