Sample records for behavior scale vabs

  1. Introduction to Symposium and Intercorrelations, Sex, and Race Differences on the Vineland Adaptive Behavior Scales.

    ERIC Educational Resources Information Center

    Childers, John S.; And Others

    Preliminary findings are presented from a study of the performance of 99 institutionalized retarded children on the Vineland Adaptive Behavior Scale (VABS), a revised form of the Vineland Social Maturity Scale (VSMS). No significant sex or race differences were revealed on test performances. Mental age was found to correlate with VABS scores with…

  2. Reliability and Validity of the Vietnamese Vineland Adaptive Behavior Scales with Preschool-Age Children

    ERIC Educational Resources Information Center

    Goldberg, Michael R.; Dill, Charles A.; Shin, Jin Y.; Nhan, Nguyen Viet

    2009-01-01

    This study was conducted to examine an adaptation of the Vineland Adaptive Behavior Scale (VABS) [Sparrow, S. S., Balla, D. A., & Cicchetti, D. V. (1984). "The Vineland Adaptive Behavior Scales." Circle Pines, MN: America Guidance Service; Sparrow, S. S., Balla, D. A., & Cicchetti, D. V. (2005). "Vineland Adaptive Behavior…

  3. Neurodevelopmental Status and Adaptive Behaviors in Preschool Children with Chronic Kidney Disease

    ERIC Educational Resources Information Center

    Duquette, Peter J.; Hooper, Stephen R.; Icard, Phil F.; Hower, Sarah J.; Mamak, Eva G.; Wetherington, Crista E.; Gipson, Debbie S.

    2009-01-01

    This study examines the early neurodevelopmental function of infants and preschool children who have chronic kidney disease (CKD). Fifteen patients with CKD are compared to a healthy control group using the "Mullen Scales of Early Learning" (MSEL) and the "Vineland Adaptive Behavior Scale" (VABS). Multivariate analysis reveals…

  4. Functional Outcome Trajectories after Out-of Hospital Pediatric Cardiac Arrest

    PubMed Central

    Silverstein, Faye S; Slomine, Beth; Christensen, James; Holubkov, Richard; Page, Kent; Dean, J. Michael; Moler, Frank

    2016-01-01

    Objective To analyze functional performance measures collected prospectively during the conduct of a clinical trial that enrolled children (up to age 18 years), resuscitated after out-of-hospital cardiac arrest, who were at high risk for poor outcomes. Design Children with Glasgow Motor Scales <5, within 6 hours of resuscitation, were enrolled in a clinical trial that compared two targeted temperature management interventions (THAPCA-OH, NCT00878644). The primary outcome, 12-month survival with Vineland Adaptive Behavior Scales, second edition (VABS-II) score ≥70, did not differ between groups. Setting 38 North American pediatric ICU’s. Participants 295 children were enrolled; 270/295 had baseline VABS-II scores ≥70; 87/270 survived one year. Interventions Targeted temperatures were 33.0°C and 36.8°C for hypothermia and normothermia groups. Measurements and Main Results Baseline measures included VABS-II, Pediatric Cerebral Performance Category(PCPC), and Pediatric Overall Performance Category (POPC). PCPC and POPC were rescored at hospital discharges; all three were scored at 3 and 12 months. In survivors with baseline VABS-II scores ≥70, we evaluated relationships of hospital discharge PCPC with 3 and 12 month scores, and between 3 and 12 month VABS-II scores. Hospital discharge PCPC scores strongly predicted 3 and 12 month PCPC (r=0.82,0.79; p<0.0001) and VABS-II scores (r=−0.81,−0.77; p<0.0001) Three month VABS-II scores strongly predicted 12 month performance (r=0.95, p<0.0001). Hypothermia treatment did not alter these relationships. Conclusions In comatose children, with Glasgow Motor Scales <5 in the initial hours after out-of-hospital cardiac arrest resuscitation, function scores at hospital discharge and at 3 months predicted 12-month performance well in the majority of survivors. PMID:27509385

  5. Nonverbal cognitive development in children with cochlear implants: relationship between the Mullen Scales of Early Learning and later performance on the Leiter International Performance Scales-Revised.

    PubMed

    Caudle, Susan E; Katzenstein, Jennifer M; Oghalai, John S; Lin, Jerry; Caudle, Donald D

    2014-02-01

    Methodologically, longitudinal assessment of cognitive development in young children has proven difficult because few measures span infancy through school age. This matter is further complicated when the child presents with a sensory deficit such as hearing loss. Few measures are validated in this population, and children who are evaluated for cochlear implantation are often reevaluated annually. The authors sought to evaluate the predictive validity of subscales of the Mullen Scales of Early Learning (MSEL) on Leiter International Performance Scales-Revised (LIPS-R) Full-Scale IQ scores. To further elucidate the relationship of these two measures, comparisons were also made with the Vineland Adaptive Behavior Scale-Second Edition (VABS), which provides a measure of adaptive functioning across the life span. Participants included 35 children (14 female, 21 male) who were evaluated both as part of the precandidacy process for cochlear implantation using the MSEL and VABS and following implantation with the LIPS-R and VABS. Hierarchical linear regression revealed that the MSEL Visual Reception subdomain score significantly predicted 52% of the variance in LIPS-R Full-Scale IQ scores at follow-up, F(1, 34) = 35.80, p < .0001, R (2) = .52, β = .72. This result suggests that the Visual Reception subscale offers predictive validity of later LIPS-R Full-Scale IQ scores. The VABS was also significantly correlated with cognitive variables at each time point.

  6. Nonverbal Cognitive Development in Children With Cochlear Implants: Relationship Between the Mullen Scales of Early Learning and Later Performance on the Leiter International Performance Scales–Revised

    PubMed Central

    Caudle, Susan E.; Katzenstein, Jennifer M.; Oghalai, John S.; Lin, Jerry; Caudle, Donald D.

    2013-01-01

    Methodologically, longitudinal assessment of cognitive development in young children has proven difficult because few measures span infancy through school age. This matter is further complicated when the child presents with a sensory deficit such as hearing loss. Few measures are validated in this population, and children who are evaluated for cochlear implantation are often reevaluated annually. The authors sought to evaluate the predictive validity of subscales of the Mullen Scales of Early Learning (MSEL) on Leiter International Performance Scales–Revised (LIPS-R) Full-Scale IQ scores. To further elucidate the relationship of these two measures, comparisons were also made with the Vineland Adaptive Behavior Scale–Second Edition (VABS), which provides a measure of adaptive functioning across the life span. Participants included 35 children (14 female, 21 male) who were evaluated both as part of the precandidacy process for cochlear implantation using the MSEL and VABS and following implantation with the LIPS-R and VABS. Hierarchical linear regression revealed that the MSEL Visual Reception subdomain score significantly predicted 52% of the variance in LIPS-R Full-Scale IQ scores at follow-up, F(1, 34) = 35.80, p < .0001, R2 = .52, β = .72. This result suggests that the Visual Reception subscale offers predictive validity of later LIPS-R Full-Scale IQ scores. The VABS was also significantly correlated with cognitive variables at each time point. PMID:22353228

  7. A 5-Year Investigation of Children's Adaptive Functioning Following Conformal Radiation Therapy for Localized Ependymoma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Netson, Kelli L.; Conklin, Heather M.; Wu Shengjie

    2012-09-01

    Purpose: Conformal and intensity modulated radiation therapies have the potential to preserve cognitive outcomes in children with ependymoma; however, functional behavior remains uninvestigated. This longitudinal investigation prospectively examined intelligence quotient (IQ) and adaptive functioning during the first 5 years after irradiation in children diagnosed with ependymoma. Methods and Materials: The study cohort consisted of 123 children with intracranial ependymoma. Mean age at irradiation was 4.60 years (95% confidence interval [CI], 3.85-5.35). Serial neurocognitive evaluations, including an age-appropriate IQ measure and the Vineland Adaptive Behavior Scales (VABS), were completed before irradiation, 6 months after treatment, and annually for 5 years. Amore » total of 579 neurocognitive evaluations were included in these analyses. Results: Baseline IQ and VABS were below normative means (P<.05), although within the average range. Linear mixed models revealed stable IQ and VABS across the follow-up period, except for the VABS Communication Index, which declined significantly (P=.015). Annual change in IQ (-.04 points) did not correlate with annual change in VABS (-.90 to +.44 points). Clinical factors associated with poorer baseline performance (P<.05) included preirradiation chemotherapy, cerebrospinal fluid shunt placement, number and extent of surgical resections, and younger age at treatment. No clinical factors significantly affected the rate of change in scores. Conclusions: Conformal and intensity modulated radiation therapies provided relative sparing of functional outcomes including IQ and adaptive behaviors, even in very young children. Communication skills remained vulnerable and should be the target of preventive and rehabilitative interventions.« less

  8. Long-term outcome of social skills intervention based on interactive LEGO play.

    PubMed

    Legoff, Daniel B; Sherman, Michael

    2006-07-01

    LEGO building materials have been adapted as a therapeutic modality for increasing motivation to participate in social skills intervention, and providing a medium through which children with social and communication handicaps can effectively interact. A 3 year retrospective study of long-term outcome for autistic spectrum children participating in LEGO therapy (N = 60) compared Vineland Adaptive Behavior Scale socialization domain (VABS-SD) and Gilliam Autism Rating Scale social interaction subscale (GARS-SI) scores preand post-treatment with a matched comparison sample (N = 57) who received comparable non-LEGO therapy. Although both groups made significant gains on the two outcome measures, LEGO participants improved significantly more than the comparison subjects. Diagnosis and pre-treatment full-scale IQ scores did not predict outcome scores; however, Vineland adaptive behavior composite, Vineland communication domain, and verbal IQ all predicted outcome on the VABS-SD, especially for the LEGO therapy group. Results are discussed in terms of implications for methods of social skills intervention for autistic spectrum disorders.

  9. Adaptive functioning and behaviour problems in relation to level of education in children and adolescents with intellectual disability.

    PubMed

    de Bildt, A; Sytema, S; Kraijer, D; Sparrow, S; Minderaa, R

    2005-09-01

    The interrelationship between adaptive functioning, behaviour problems and level of special education was studied in 186 children with IQs ranging from 61 to 70. The objective was to increase the insight into the contribution of adaptive functioning and general and autistic behaviour problems to the level of education in children with intellectual disability (ID). Children from two levels of special education in the Netherlands were compared with respect to adaptive functioning [Vineland Adaptive Behavior Scales (VABS)], general behaviour problems [Child Behavior Checklist (CBCL)] and autistic behaviour problems [Autism Behavior Checklist (ABC)]. The effect of behaviour problems on adaptive functioning, and the causal relationships between behaviour problems, adaptive functioning and level of education were investigated. Children in schools for mild learning problems had higher VABS scores, and lower CBCL and ABC scores. The ABC had a significant effect on the total age equivalent of the VABS in schools for severe learning problems, the CBCL in schools for mild learning problems. A direct effect of the ABC and CBCL total scores on the VABS age equivalent was found, together with a direct effect of the VABS age equivalent on level of education and therefore an indirect effect of ABC and CBCL on level of education. In the children with the highest level of mild ID, adaptive functioning seems to be the most important factor that directly influences the level of education that a child attends. Autistic and general behaviour problems directly influence the level of adaptive functioning. Especially, autistic problems seem to have such a restrictive effect on the level of adaptive functioning that children do not reach the level of education that would be expected based on IQ. Clinical implications are discussed.

  10. Revisiting Cognitive and Adaptive Functioning in Children and Adolescents with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Matthews, Nicole L.; Pollard, Elena; Ober-Reynolds, Sharman; Kirwan, Janet; Malligo, Amanda; Smith, Christopher J.

    2015-01-01

    Profiles of performance on the Stanford Binet Intelligence Scales (SB5) and Vineland Adaptive Behavior Scales (VABS) were examined in 73 children and adolescents with autism spectrum disorder. SB5 cognitive profiles were observed to be similar between participants with and without early language delay, but different between participants with and…

  11. Associations of Gross Motor Delay, Behavior, and Quality of Life in Young Children With Autism Spectrum Disorder.

    PubMed

    Hedgecock, James B; Dannemiller, Lisa A; Shui, Amy M; Rapport, Mary Jane; Katz, Terry

    2018-04-01

    Young children with autism spectrum disorder (ASD) often have gross motor delays that may accentuate problem daytime behavior and health-related quality of life (QoL). The objective of this study was to describe the degree of gross motor delays in young children with ASD and associations of gross motor delays with problem daytime behavior and QoL. The primary hypothesis was that Gross motor delays significantly modifies the associations between internalizing or externalizing problem daytime behavior and QoL. This study used a cross-sectional, retrospective analysis. Data from 3253 children who were 2 to 6 years old and who had ASD were obtained from the Autism Speaks Autism Treatment Network and analyzed using unadjusted and adjusted linear regression. Measures included the Vineland Adaptive Behavior Scales, 2nd edition, gross motor v-scale score (VABS-GM) (for Gross motor delays), the Child Behavior Checklist (CBCL) (for Problem daytime behavior), and the Pediatric Quality of Life Inventory (PedsQL) (for QoL). The mean VABS-GM was 12.12 (SD = 2.2), representing performance at or below the 16th percentile. After adjustment for covariates, the internalizing CBCL t score decreased with increasing VABS-GM (β = - 0.64 SE = 0.12). Total and subscale PedsQL scores increased with increasing VABS-GM (for total score: β = 1.79 SE = 0.17; for subscale score: β = 0.9-2.66 SE = 0.17-0.25). CBCL internalizing and externalizing t scores decreased with increasing PedsQL total score (β = - 0.39 SE = 0.01; β = - 0.36 SE = 0.01). The associations between CBCL internalizing or externalizing t scores and PedsQL were significantly modified by VABSGM (β = - 0.026 SE = 0.005]; β = - 0.019 SE = 0.007). The study lacked ethnic and socioeconomic diversity. Measures were collected via parent report without accompanying clinical assessment. Cross motor delay was independently associated with Problem daytime behavior and QoL in children with ASD. Gross motor delay modified the association between Problem daytime behavior and QoL. Children with ASD and co-occurring internalizing Problem daytime behavior had greater Gross motor delays than children without internalizing Problem daytime behavior; therefore, these children may be most appropriate for early physical therapist evaluation.

  12. Evolution of an adaptive behavior and its sensory receptors promotes eye regression in blind cavefish: response to Borowsky (2013).

    PubMed

    Yoshizawa, Masato; O'Quin, Kelly E; Jeffery, William R

    2013-07-11

    Vibration attraction behavior (VAB) is the swimming of fish toward an oscillating object, a behavior that is likely adaptive because it increases foraging efficiency in darkness. VAB is seen in a small proportion of Astyanax surface-dwelling populations (surface fish) but is pronounced in cave-dwelling populations (cavefish). In a recent study, we identified two quantitative trait loci for VAB on Astyanax linkage groups 2 and 17. We also demonstrated that a small population of superficial neuromast sensors located within the eye orbit (EO SN) facilitate VAB, and two quantitative trait loci (QTL) were identified for EO SN that were congruent with those for VAB. Finally, we showed that both VAB and EO SN are negatively correlated with eye size, and that two (of several) QTL for eye size overlap VAB and EO SN QTLs. From these results, we concluded that the adaptive evolution of VAB and EO SN has contributed to the indirect loss of eyes in cavefish, either as a result of pleiotropy or tight physical linkage of the mutations underlying these traits. In a subsequent commentary, Borowsky argues that there is poor experimental support for our conclusions. Specifically, Borowsky states that: (1) linkage groups (LGs) 2 and 17 harbor QTL for many traits and, therefore, no evidence exists for an exclusive interaction among the overlapping VAB, EO SN and eye size QTL; (2) some of the QTL we identified are too broad (>20 cM) to support the hypothesis of correlated evolution due to pleiotropy or hitchhiking; and (3) VAB is unnecessary to explain the indirect evolution of eye-loss since the negative polarity of numerous eye QTL is consistent with direct selection against eyes. Borowsky further argues that (4) it is difficult to envision an evolutionary scenario whereby VAB and EO SN drive eye loss, since the eyes must first be reduced in order to increase the number of EO SN and, therefore, VAB. In this response, we explain why the evidence of one trait influencing eye reduction is stronger for VAB than other traits, and provide further support for a scenario whereby elaboration of VAB in surface fish may precede complete eye-loss.

  13. Longitudinal Investigation of Adaptive Functioning following Conformal Irradiation for Pediatric Craniopharyngioma and Low-Grade Glioma

    PubMed Central

    Netson, Kelli L.; Conklin, Heather M.; Wu, Shengjie; Xiong, Xiaoping; Merchant, Thomas E.

    2013-01-01

    Purpose Children treated for brain tumors with conformal radiation therapy experience preserved cognitive outcomes. Early evidence suggests that adaptive functions or independent living skills may be spared. This longitudinal investigation prospectively examined intellectual and adaptive functioning during the first 5 years following irradiation for childhood craniopharyngioma and low-grade glioma (LGG). The effect of visual impairment on adaptive outcomes was investigated. Methods and Materials Children with craniopharyngioma (n=62) and LGG (n=77) were treated using conformal or intensity-modulated radiation therapy. The median age was 8.05 years (3.21 years –17.64 years) and 8.09 years (2.20 years–19.27 years), respectively. Serial cognitive evaluations including measures of intelligence quotient (IQ) and the Vineland Adaptive Behavior Scales (VABS) were conducted at pre-irradiation baseline, 6 months after treatment, and annually through 5 years. A total of 588 evaluations were completed during the follow-up period. Results Baseline assessment revealed no deficits in IQ and VABS indices for children with craniopharyngioma, with significant (p < .05) longitudinal decline in VABS Communication and Socialization indices. Clinical factors associated with more rapid decline included females and pre-irradiation chemotherapy (interferon). The only change in VABS Daily Living Skills correlated with IQ change (r = .34; p = .01) in children with craniopharyngioma. Children with LGG performed below population norms (p < .05) at baseline on VABS Communication, Daily Living Indices, and the Adaptive Behavior Composite, with significant (p < .05) longitudinal decline limited to VABS Communication. Older age at irradiation was a protective factor against longitudinal decline. Severe visual impairment did not independently correlate with poorer adaptive outcomes for either tumor group. Conclusions There was relative sparing of post-irradiation functional outcomes over time in this sample. Baseline differences in functional abilities prior to the initiation of irradiation suggested that other factors influence functional outcomes above and beyond the effects of irradiation. PMID:23245284

  14. Longitudinal Investigation of Adaptive Functioning Following Conformal Irradiation for Pediatric Craniopharyngioma and Low-Grade Glioma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Netson, Kelli L.; Conklin, Heather M.; Wu, Shengjie

    2013-04-01

    Purpose: Children treated for brain tumors with conformal radiation therapy experience preserved cognitive outcomes. Early evidence suggests that adaptive functions or independent-living skills may be spared. This longitudinal investigation prospectively examined intellectual and adaptive functioning during the first 5 years following irradiation for childhood craniopharyngioma and low-grade glioma (LGG). The effect of visual impairment on adaptive outcomes was investigated. Methods and Materials: Children with craniopharyngioma (n=62) and LGG (n=77) were treated using conformal or intensity modulated radiation therapy. The median age was 8.05 years (3.21-17.64 years) and 8.09 years (2.20-19.27 years), respectively. Serial cognitive evaluations including measures of intelligence quotientmore » (IQ) and the Vineland Adaptive Behavior Scales (VABS) were conducted at preirradiation baseline, 6 months after treatment, and annually through 5 years. Five hundred eighty-eight evaluations were completed during the follow-up period. Results: Baseline assessment revealed no deficits in IQ and VABS indices for children with craniopharyngioma, with significant (P<.05) longitudinal decline in VABS Communication and Socialization indices. Clinical factors associated with more rapid decline included females and preirradiation chemotherapy (interferon). The only change in VABS Daily Living Skills correlated with IQ change (r=0.34; P=.01) in children with craniopharyngioma. Children with LGG performed below population norms (P<.05) at baseline on VABS Communication, Daily Living Indices, and the Adaptive Behavior Composite, with significant (P<.05) longitudinal decline limited to VABS Communication. Older age at irradiation was a protective factor against longitudinal decline. Severe visual impairment did not independently correlate with poorer adaptive outcomes for either tumor group. Conclusions: There was relative sparing of postirradiation functional outcomes over time in this sample. Baseline differences in functional abilities before the initiation of irradiation suggested that other factors influence functional outcomes above and beyond the effects of irradiation.« less

  15. Longitudinal Trajectories of Aberrant Behavior in Fragile X Syndrome

    PubMed Central

    Hustyi, Kristin M.; Hall, Scott S.; Jo, Booil; Lightbody, Amy A.; Reiss, Allan L.

    2016-01-01

    The Aberrant Behavior Checklist—Community (ABC-C; Aman, Burrow, & Wolford, 1995) has been increasingly adopted as a primary tool for measuring behavioral change in clinical trials for individuals with fragile X syndrome (FXS). To our knowledge, however, no study has documented the longitudinal trajectory of aberrant behaviors in individuals with FXS using the ABC-C. As part of a larger longitudinal study, we examined scores obtained on the ABC-C subscales for 124 children and adolescents (64 males, 60 females) with FXS who had two or more assessments (average interval between assessments was approximately 4 years). Concomitant changes in age-equivalent scores on the Vineland Adaptive Behavior Scales (VABS) were also examined. As expected for an X-linked genetic disorder, males with FXS obtained significantly higher scores on all subscales of the ABC-C and significantly lower age-equivalent scores on the VABS than females with FXS. In both males and females with FXS, scores on the Irritability/Agitation and Hyperactivity/Noncompliance subscales of the ABC-C decreased significantly with age, with little to no change occurring over time on the Lethargy/Social Withdrawal, Stereotypic Behavior, and Inappropriate Speech subscales. The decrease in scores on the Hyperactivity/Noncompliance domain was significantly greater for males than for females. In both males and females, age-equivalent scores on the VABS increased significantly over this developmental period. These results establish a basis upon which to evaluate long-term outcomes from intervention-based research. However, longitudinal direct observational studies are needed to establish whether the severity of problem behavior actually decreases over time in this population. PMID:25129200

  16. Evolution of a behavioral shift mediated by superficial neuromasts helps cavefish find food in darkness

    PubMed Central

    Yoshizawa, Masato; Gorčiki, Špela; Soares, Daphne; Jeffery, William R.

    2010-01-01

    Summary How cave animals adapt to life in darkness is a poorly understood aspect of evolutionary biology [1]. Here we identify a behavioral shift and its morphological basis in Astyanax mexicanus, a teleost with a sighted surface dwelling form (surface fish) and various blind cave dwelling forms (cavefish) [2–4]. Vibration attraction behavior (VAB) is the ability of fish to swim toward the source of a water disturbance in darkness. VAB was typically seen in cavefish, rarely in surface fish, and advantageous for feeding success in the dark. The potential for showing VAB has a genetic component and is linked to the mechanosensory function of the lateral line. VAB was evoked by vibration stimuli peaking at 35 Hz, blocked by lateral line inhibitors, appeared after developmental increases in superficial neuromast (SN) number and size [5–7], and was significantly reduced by bilateral ablation of SN. We conclude that VAB and SN enhancement co-evolved to compensate for loss of vision and help blind cavefish find food in darkness. PMID:20705469

  17. Apparent Diffusion Coefficient Value Changes and Clinical Correlation in 90 Cases of Cytomegalovirus-Infected Fetuses with Unremarkable Fetal MRI Results.

    PubMed

    Kotovich, D; Guedalia, J S B; Hoffmann, C; Sze, G; Eisenkraft, A; Yaniv, G

    2017-07-01

    Cytomegalovirus is the leading intrauterine infection. Fetal MR imaging is an accepted tool for fetal brain evaluation, yet it still lacks the ability to accurately predict the extent of the neurodevelopmental impairment, especially in fetal MR imaging scans with unremarkable findings. Our hypothesis was that intrauterine cytomegalovirus infection causes diffusional changes in fetal brains and that those changes may correlate with the severity of neurodevelopmental deficiencies. A retrospective analysis was performed on 90 fetal MR imaging scans of cytomegalovirus-infected fetuses with unremarkable results and compared with a matched gestational age control group of 68 fetal head MR imaging scans. ADC values were measured and averaged in the frontal, parietal, occipital, and temporal lobes; basal ganglia; thalamus; and pons. For neurocognitive assessment, the Vineland Adaptive Behavior Scales, Second Edition (VABS-II) was used on 58 children in the cytomegalovirus-infected group. ADC values were reduced for the cytomegalovirus-infected fetuses in most brain areas studied. The VABS-II showed no trend for the major domains or the composite score of the VABS-II for the cytomegalovirus-infected children compared with the healthy population distribution. Some subdomains showed an association between ADC values and VABS-II scores. Cytomegalovirus infection causes diffuse reduction in ADC values in the fetal brain even in unremarkable fetal MR imaging scans. Cytomegalovirus-infected children with unremarkable fetal MR imaging scans do not deviate from the healthy population in the VABS-II neurocognitive assessment. ADC values were not correlated with VABS-II scores. However, the lack of clinical findings, as seen in most cytomegalovirus-infected fetuses, does not eliminate the possibility of future neurodevelopmental pathology. © 2017 by American Journal of Neuroradiology.

  18. Assessments Used to Diagnose Developmental Coordination Disorder: Do Their Underlying Constructs Match the Diagnostic Criteria?

    ERIC Educational Resources Information Center

    Darsaklis, Vasiliki; Snider, Laurie M.; Majnemer, Annette; Mazer, Barbara

    2013-01-01

    This study examined the constructs underlying the Movement Assessment Battery for Children-2 (M-ABC-2), Bruninks-Oseretsky Test of Motor Proficiency (BOTMP) and Vineland Adaptive Behavior Scale-2 (VABS-2) using the framework of the International Classification of Functioning Disability and Health--Child Youth version (ICF-CY) and the diagnostic…

  19. Evolution of the developmental plasticity and a coupling between left mechanosensory neuromasts and an adaptive foraging behavior.

    PubMed

    Fernandes, Vânia Filipa Lima; Macaspac, Christian; Lu, Louise; Yoshizawa, Masato

    2018-05-18

    Many animal species exhibit laterality in sensation and behavioral responses, namely, the preference for using either the left or right side of the sensory system. For example, some fish use their left eye when observing social stimuli, whereas they use their right eye to observe novel objects. However, it is largely unknown whether such laterality in sensory-behavior coupling evolves during rapid adaptation processes. Here, in the Mexican tetra, Astyanax mexicanus, we investigate the laterality in the relationship between an evolved adaptive behavior, vibration attraction behavior (VAB), and its main sensors, mechanosensory neuromasts. A. mexicanus has a surface-dwelling form and cave-dwelling forms (cavefish), whereby a surface fish ancestor colonized the new environment of a cave, eventually evolving cave-type morphologies such as increased numbers of neuromasts at the cranium. These neuromasts are known to regulate VAB, and it is known that, in teleosts, the budding (increasing) process of neuromasts is accompanied with dermal bone formation. This bone formation is largely regulated by endothelin signaling. To assess the evolutionary relationship between bone formation, neuromast budding, and VAB, we treated 1-3 month old juvenile fish with endothelin receptor antagonists. This treatment significantly increased cranial neuromasts in both surface and cavefish, and the effect was significantly more pronounced in cavefish. Antagonist treatment also increased the size of dermal bones in cavefish, but neuromast enhancement was observed earlier than dermal bone formation, suggesting that endothelin signaling may independently regulate neuromast development and bone formation. In addition, although we did not detect a major change in VAB level under this antagonist treatment, cavefish did show a positive correlation of VAB with the number of neuromasts on their left side but not their right. This laterality in correlation was observed when VAB emerged during cavefish development, but it was not seen in surface fish under any conditions tested, suggesting this laterality emerged through an evolutionary process. Above all, cavefish showed higher developmental plasticity in neuromast number and bone formation, and they showed an asymmetric correlation between the number of left-right neuromasts and VAB. Published by Elsevier Inc.

  20. Sex differences in parent-reported executive functioning and adaptive behavior in children and young adults with autism spectrum disorder.

    PubMed

    White, Emily I; Wallace, Gregory L; Bascom, Julia; Armour, Anna C; Register-Brown, Kelly; Popal, Haroon S; Ratto, Allison B; Martin, Alex; Kenworthy, Lauren

    2017-10-01

    This study is the largest to date examining executive function and adaptive skills in females with autism spectrum disorder (ASD). Its primary aim was to utilize parent ratings of real-world executive functioning and adaptive behavior to better understand whether females with ASD differ from males with ASD in these areas of everyday functioning. We compared 79 females with ASD to 158 males with ASD (ages 7-18) who were statistically matched on age, IQ, and level of ADHD or ASD traits. All participants were assessed using the Behavior Rating Inventory of Executive Function (BRIEF) and a subset (56 females and 130 males) also received the Vineland Adaptive Behavior Scales (VABS). Females were rated by parents as having greater problems with executive function on the BRIEF. Parents also rated females as exhibiting more difficulties than males on the Daily Living Skills domain of the VABS. There was a correlation between increased global EF difficulty and decreased adaptive ability in both males and females. Our results indicate relative weaknesses for females compared to males diagnosed with ASD on executive function and daily living skills. These differences occur in the absence of sex differences in our sample in age, IQ, clinician ratings of core ASD symptomatology, parent ratings of ADHD symptoms, and parent-reported social and communication adaptive skills on the VABS. These findings indicate specific liabilities in real world EF and daily living skills for females with ASD and have important implications for targeting their treatments. Autism Res 2017, 10: 1653-1662. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.

  1. The New DSM-5 Impairment Criterion: A Challenge to Early Autism Spectrum Disorder Diagnosis?

    ERIC Educational Resources Information Center

    Zander, Eric; Bölte, Sven

    2015-01-01

    The possible effect of the DSM-5 impairment criterion on diagnosing autism spectrum disorder (ASD) in young children was examined in 127 children aged 20-47 months with a DSM-IV-TR clinical consensus diagnosis of ASD. The composite score of the Vineland Adaptive Behavior Scales (VABS) served as a proxy for the DSM-5 impairment criterion. When…

  2. Donepezil for treatment of cognitive dysfunction in children with Down syndrome aged 10-17.

    PubMed

    Kishnani, Priya S; Heller, James H; Spiridigliozzi, Gail A; Lott, Ira; Escobar, Luis; Richardson, Sharon; Zhang, Richard; McRae, Thomas

    2010-12-01

    The objective of this 10-week, randomized, double-blind, placebo-controlled multicenter study was to assess the efficacy and safety of donepezil for the treatment of cognitive dysfunction exhibited by children with Down syndrome (DS). Intervention comprised donepezil (2.5-10 mg/day) in children (aged 10-17 years) with DS of mild-to-moderate severity. The primary measures were the Vineland-II Adaptive Behavior Scales (VABS-II) Parent/Caregiver Rating Form (PCRF) the sum of nine subdomain standardized scores and standard safety measures. Secondary measures included the VABS-II/PCRF scores on the following domains and their respective individual subdomains: Communication (receptive, expressive, and written); Daily Living Skills (personal, domestic, and community); Socialization (interpersonal relationships, play and leisure time, and coping skills), and scores on the Test of Verbal Expression and Reasoning, a subject-performance-based measure of expressive language. At baseline, 129 participants were assigned treatment with donepezil or placebo. During the double-blind phase, VABS II/PCRF sum of the nine subdomain standardized scores, called v-scores, improved significantly from baseline in both groups (P < 0.0001), with no significant between-group differences. This trial failed to demonstrate any benefit for donepezil versus placebo in children and adolescents with DS, although donepezil appeared to be well tolerated. © 2010 Wiley-Liss, Inc.

  3. Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome.

    PubMed

    Berry-Kravis, Elizabeth; Sumis, Allison; Hervey, Crystal; Nelson, Michael; Porges, Stephen W; Weng, Ning; Weiler, Ivan Jeanne; Greenough, William T

    2008-08-01

    In fragile X syndrome (FXS), it is hypothesized that absence of the fragile X mental retardation protein (FMRP) disrupts regulation of group 1 metabotropic glutamate receptor (mGluR and mGluR5)-dependent translation in dendrites. Lithium reduces mGluR-activated translation and reverses phenotypes in the dfxr mutant fly and fmr1 knockout mouse. This pilot add-on trial was conducted to evaluate safety and efficacy of lithium in humans with FXS. Fifteen individuals with FXS, ages 6-23, received lithium titrated to levels of 0.8-1.2 mEq/L. The primary outcome measure, the Aberrant Behavior Checklist --Community Edition (ABC-C) Irritability Subscale, secondary outcome measures (other ABC-C subscales, clinical global improvement scale (CGI), visual analog scale for behavior (VAS), Vineland Adaptive Behavior Scale (VABS)), exploratory cognitive and psychophysiological measures and an extracellular signal-regulated kinase (ERK) activation assay were administered at baseline and 2 months of treatment. Side effects were quantified with a standardized checklist and lithium level, complete blood count (CBC), thyroid stimulating hormone (TSH), and chemistry screen were done at baseline, 2 weeks, 4 weeks and 2 months. The only significant treatment-related side effects were polyuria/polydipsia (n = 7) and elevated TSH (n = 4). Although the ABC-C Irritability Subscale showed only a trend toward improvement, there was significant improvement in the Total ABC-C score (p = 0.005), VAS (p = 0.003), CGI (p = 0.002), VABS Maladaptive Behavior Subscale (p = 0.007), and RBANS List Learning (p = 0.03) and an enhanced ERK activation rate (p = 0.007). Several exploratory tasks proved too difficult for lower-functioning FXS subjects. Results from this study are consistent with results in mouse and fly models of FXS, and suggest that lithium is well-tolerated and provides functional benefits in FXS, possibly by modifying the underlying neural defect. A placebo-controlled trial of lithium in FXS is warranted.

  4. Eye regression in blind Astyanax cavefish may facilitate the evolution of an adaptive behavior and its sensory receptors.

    PubMed

    Borowsky, Richard

    2013-07-11

    The forces driving the evolutionary loss or simplification of traits such as vision and pigmentation in cave animals are still debated. Three alternative hypotheses are direct selection against the trait, genetic drift, and indirect selection due to antagonistic pleiotropy. Recent work establishes that Astyanax cavefish exhibit vibration attraction behavior (VAB), a presumed behavioral adaptation to finding food in the dark not exhibited by surface fish. Genetic analysis revealed two regions in the genome with quantitative trait loci (QTL) for both VAB and eye size. These observations were interpreted as genetic evidence that selection for VAB indirectly drove eye regression through antagonistic pleiotropy and, further, that this is a general mechanism to account for regressive evolution. These conclusions are unsupported by the data; the analysis fails to establish pleiotropy and ignores the numerous other QTL that map to, and potentially interact, in the same regions. It is likely that all three forces drive evolutionary change. We will be able to distinguish among them in individual cases only when we have identified the causative alleles and characterized their effects.

  5. STS-79 Rolls over from OPF to VAB

    NASA Technical Reports Server (NTRS)

    1996-01-01

    A vantage point high atop the Vehicle Assembly Building (VAB) shrinks the size and scale of the orbiter Atlantis as it is rolled from the Orbiter Processing Facility to the VAB. During the five working days it spends inside the huge building, Atlantis will be mated to the external tank/twin solid rocket booster assembly, and then rolled out to Launch Pad 39A. Here, the SPACEHAB Double Module will be installed in the orbiter's payload bay and final launch preparations will get underway. Atlantis is scheduled for liftoff on Mission STS-79 , the fourth docking with the Russian Space Station Mir, scheduled for July 31.

  6. Norms for developmental milestones using VABS-II and association with anthropometric measures among apparently healthy urban Indian preschool children.

    PubMed

    Selvam, Sumithra; Thomas, Tinku; Shetty, Priya; Zhu, Jianjun; Raman, Vijaya; Khanna, Deepti; Mehra, Ruchika; Kurpad, Anura V; Srinivasan, Krishnamachari

    2016-12-01

    Assessment of developmental milestones based on locally developed norms is critical for accurate estimate of overall development of a child's cognitive, behavioral, social, and emotional development. A cross-sectional study was done to develop age specific norms for developmental milestones using Vineland Adaptive Behavior Scales (VABS-II) (Sparrow, Cicchetti, & Balla, 2005) for apparently healthy children from 2 to 5 years from urban Bangalore, India, and to examine its association with anthropometric measures. Mothers (or caregivers) of 412 children participated in the study. Age-specific norms using inferential norming method and adaptive levels for all domains and subdomains were derived. Low adaptive level, also called delayed developmental milestone, was observed in 2.3% of the children, specifically 2.7% in motor and daily living skills and 2.4% in communication skills. When these children were assessed on the existing U.S. norms, there was a significant overestimation of delayed development in socialization and motor skills, whereas delay in communication and daily living skills were underestimated (all p < .01). Multiple linear regression revealed that stunted and underweight children had significantly lower developmental scores for communication and motor skills compared with normal children (β coefficient ranges from 2.6-5.3; all p < .01). In the absence of Indian normative data for VABS-II in preschool children, the prevalence of developmental delay could either be under- or overestimated using Western norms. Thus, locally referenced norms are critical for reliable assessments of development in children. Stunted and underweight children are more likely to have poorer developmental scores compared with healthy children. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  7. Long-term outcome of a cohort of adults with autism and intellectual disability: A pilot prospective study.

    PubMed

    Fusar-Poli, Laura; Brondino, Natascia; Orsi, Paolo; Provenzani, Umberto; De Micheli, Andrea; Ucelli di Nemi, Stefania; Barale, Francesco; Politi, Pierluigi

    2017-01-01

    Autism spectrum disorders (ASD) are a long-life condition frequently associated with intellectual disability. To date, long-term outcome has been investigated mostly in ASD people with average or above-average intelligence and there is a paucity of data about autistic adults with comorbid intellectual disability. The aim of the present study is to assess long-term variations of adaptive abilities in a sample of autistic adults with intellectual disability and severe language impairment. 22 adults (17 males and 5 females) affected by autism and intellectual disability were recruited and evaluated after their admission in an Italian farm-community. Vineland Adaptive Behavior Scales (VABS) were used as outcome measure for adaptive abilities. After ten years the measurement was repeated in order to study the evolution of patients' skills along time. Additionally, sociodemographic variables, changes in medication and comorbidities were recorded. No statistically significant improvement neither deterioration was found according to VABS raw scores in the entire sample. On the contrary, a significant improvement was evident in standard scores for the Adaptive Behavior Composite Scale and for each domain. In general, our patients remained stable in adaptive abilities. However, our results are not generalisable to the entire autistic population, but only to inpatients with autism and comorbid intellectual disability. New measures should be developed in order to better assess changes in this particular population. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Long-term effects of PECS on social-communicative skills of children with autism spectrum disorders: a follow-up study.

    PubMed

    Lerna, Anna; Esposito, Dalila; Conson, Massimiliano; Massagli, Angelo

    2014-01-01

    The Picture Exchange Communication System (PECS) is a popular augmentative communication system frequently used with 'nonverbal' children with autism. Several studies suggested that PECS could represent an effective tool for promoting improvement of several social-communicative skills. Only sparse evidence is instead available on the long-term effectiveness of this treatment system. To test the long-term effects of PECS, for which a follow-up study was conducted by assessing social-communicative skills in nonverbal preschool children with autism after 12 months from treatment completion. Two groups of children (N = 14) were assessed; one group had completed the PECS training and the other conventional language therapy (CLT). At follow-up all children received the same pre- and post-treatment assessment. Outcome measures were the following: Communication and Social domains of Autism Diagnostic Observation Schedule (ADOS); Language and Personal-Social subscales of the Griffiths' Mental Developmental Scales (GMDS); Communication and Social Abilities domains of the Vineland Adaptive Behavior Scales (VABS); and several social-communicative variables coded in an unstructured setting. The PECS group showed significant improvements compared with the CLT group on ADOS severity scores (Communication, Social and Total), on GMDS Social domain and on VABS Communication and Social domains. PECS-related gains on the VABS Social domain and on specific social-communicative measures coded during free-play, i.e. frequency of joint attention and initiation, and duration of cooperative play, were stable after 1-year follow-up. Cooperative play continued to improve on follow-up with respect to both post- and pre-treatment assessment. These findings demonstrated that PECS training can promote long-term enhancement of specific socio-communicative skills in children with autism. © 2014 Royal College of Speech and Language Therapists.

  9. Therapeutic hypothermia after out-of-hospital cardiac arrest in children.

    PubMed

    Moler, Frank W; Silverstein, Faye S; Holubkov, Richard; Slomine, Beth S; Christensen, James R; Nadkarni, Vinay M; Meert, Kathleen L; Clark, Amy E; Browning, Brittan; Pemberton, Victoria L; Page, Kent; Shankaran, Seetha; Hutchison, Jamie S; Newth, Christopher J L; Bennett, Kimberly S; Berger, John T; Topjian, Alexis; Pineda, Jose A; Koch, Joshua D; Schleien, Charles L; Dalton, Heidi J; Ofori-Amanfo, George; Goodman, Denise M; Fink, Ericka L; McQuillen, Patrick; Zimmerman, Jerry J; Thomas, Neal J; van der Jagt, Elise W; Porter, Melissa B; Meyer, Michael T; Harrison, Rick; Pham, Nga; Schwarz, Adam J; Nowak, Jeffrey E; Alten, Jeffrey; Wheeler, Derek S; Bhalala, Utpal S; Lidsky, Karen; Lloyd, Eric; Mathur, Mudit; Shah, Samir; Wu, Theodore; Theodorou, Andreas A; Sanders, Ronald C; Dean, J Michael

    2015-05-14

    Therapeutic hypothermia is recommended for comatose adults after witnessed out-of-hospital cardiac arrest, but data about this intervention in children are limited. We conducted this trial of two targeted temperature interventions at 38 children's hospitals involving children who remained unconscious after out-of-hospital cardiac arrest. Within 6 hours after the return of circulation, comatose patients who were older than 2 days and younger than 18 years of age were randomly assigned to therapeutic hypothermia (target temperature, 33.0°C) or therapeutic normothermia (target temperature, 36.8°C). The primary efficacy outcome, survival at 12 months after cardiac arrest with a Vineland Adaptive Behavior Scales, second edition (VABS-II), score of 70 or higher (on a scale from 20 to 160, with higher scores indicating better function), was evaluated among patients with a VABS-II score of at least 70 before cardiac arrest. A total of 295 patients underwent randomization. Among the 260 patients with data that could be evaluated and who had a VABS-II score of at least 70 before cardiac arrest, there was no significant difference in the primary outcome between the hypothermia group and the normothermia group (20% vs. 12%; relative likelihood, 1.54; 95% confidence interval [CI], 0.86 to 2.76; P=0.14). Among all the patients with data that could be evaluated, the change in the VABS-II score from baseline to 12 months was not significantly different (P=0.13) and 1-year survival was similar (38% in the hypothermia group vs. 29% in the normothermia group; relative likelihood, 1.29; 95% CI, 0.93 to 1.79; P=0.13). The groups had similar incidences of infection and serious arrhythmias, as well as similar use of blood products and 28-day mortality. In comatose children who survived out-of-hospital cardiac arrest, therapeutic hypothermia, as compared with therapeutic normothermia, did not confer a significant benefit in survival with a good functional outcome at 1 year. (Funded by the National Heart, Lung, and Blood Institute and others; THAPCA-OH ClinicalTrials.gov number, NCT00878644.).

  10. Developmental and functional outcomes in children with global developmental delay or developmental language impairment.

    PubMed

    Shevell, Michael; Majnemer, Annette; Platt, Robert W; Webster, Richard; Birnbaum, Rena

    2005-10-01

    Preschool children diagnosed with either global developmental delay (GDD) or developmental language impairment (DLI) were reassessed during their early school years with standardized developmental (Battelle Developmental Inventory [BDI]) and functional (Vineland Adaptive Behavior Scale [VABS]) outcome measures. Of an original cohort of 99 children with GDD and 70 children with DLI assessed and diagnosed at a mean age of 3 years 5 months (SD 1.1) and 3 years 7 months (SD 0.7) respectively, 48 children (34 [71%] males) with GDD and 43 children (36 [84%] males) with DLI were reassessed at a mean age of 7 years 4 months (SD 0.9) and 7 years 5 months (SD 0.7) respectively. The overall total mean BDI score for children with GDD was 66.4 (SD 4.3) versus 71.9 (SD 8.2) for children with DLI (p=0.002). On each subdomain of the BDI, except communication, mean scores for the GDD group were significantly lower than for the DLI group (p<0.05). Similarly, the VABS total score for the GDD group was significantly lower than for the DLI group (p<0.001). For each subdomain of the VABS, the GDD group scored significantly lower than the DLI group (p<0.001). The proportion of children falling below meaningful cut-offs on the outcome measures selected was significantly higher for those initially diagnosed with GDD. Preschool diagnosis of either GDD or DLI has later prognostic validity with regard to persisting developmental and functional deficits.

  11. Association between the oxytocin receptor (OXTR) gene and autism: relationship to Vineland Adaptive Behavior Scales and cognition.

    PubMed

    Lerer, E; Levi, S; Salomon, S; Darvasi, A; Yirmiya, N; Ebstein, R P

    2008-10-01

    Evidence both from animal and human studies suggests that common polymorphisms in the oxytocin receptor (OXTR) gene are likely candidates to confer risk for autism spectrum disorders (ASD). In lower mammals, oxytocin is important in a wide range of social behaviors, and recent human studies have shown that administration of oxytocin modulates behavior in both clinical and non-clinical groups. Additionally, two linkage studies and two recent association investigations also underscore a possible role for the OXTR gene in predisposing to ASD. We undertook a comprehensive study of all 18 tagged SNPs across the entire OXTR gene region identified using HapMap data and the Haploview algorithm. Altogether 152 subjects diagnosed with ASDs (that is, DSM IV autistic disorder or pervasive developmental disorder--NOS) from 133 families were genotyped (parents and affected siblings). Both individual SNPs and haplotypes were tested for association using family-based association tests as provided in the UNPHASED set of programs. Significant association with single SNPs and haplotypes (global P-values <0.05, following permutation test adjustment) were observed with ASD. Association was also observed with IQ and the Vineland Adaptive Behavior Scales (VABS). In particular, a five-locus haplotype block (rs237897-rs13316193-rs237889-rs2254298-rs2268494) was significantly associated with ASD (nominal global P=0.000019; adjusted global P=0.009) and a single haplotype (carried by 7% of the population) within that block showed highly significant association (P=0.00005). This is the third association study, in a third ethnic group, showing that SNPs and haplotypes in the OXTR gene confer risk for ASD. The current investigation also shows association with IQ and total VABS scores (as well as the communication, daily living skills and socialization subdomains), suggesting that this gene shapes both cognition and daily living skills that may cross diagnostic boundaries.

  12. PIONEER VENUS 2 MULTI-PROBE PARACHUTE TESTS IN THE VAB SHOWS OPEN PARACHUTE

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A parachute system, designed to carry an instrument-laden probe down through the dense atmosphere of torrid, cloud-shrouded Venus, was tested in KSC's Vehicle Assembly Building. The tests are in preparation for a Pioneer multi-probe mission to Venus scheduled for launch from KSC in 1978. Full-scale (12-foot diameter) parachutes with simulated pressure vessels weighing up to 45 pounds were dropped from heights of up to 450 feet tot he floor of the VAB where the impact was cushioned by a honeycomb cardboard impact arrestor. The VAB offers an ideal, wind-free testing facility at no additional construction cost and was used for similar tests of the parachute system for the twin Viking spacecraft scheduled for launch toward Mars in August.

  13. PIONEER VENUS 2 MULTI-PROBE PARACHUTE TESTS IN VAB WITH PARACHUTE HOISTED HIGH

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A parachute system, designed to carry an instrument-laden probe down through the dense atmosphere of torrid, cloud-shrouded Venus, was tested in KSC's Vehicle Assembly Building. The tests are in preparation for a Pioneer multi-probe mission to Venus scheduled for launch from KSC in 1978. Full-scale (12-foot diameter) parachutes with simulated pressure vessels weighing up to 45 pounds were dropped from heights of up to 450 feet tot he floor of the VAB where the impact was cushioned by a honeycomb cardboard impact arrestor. The VAB offers an ideal, wind-free testing facility at no additional construction cost and was used for similar tests of the parachute system for the twin Viking spacecraft scheduled for launch toward Mars in August.

  14. PIONEER VENUS 2 MULTI-PROBE PARACHUTE TESTS IN VAB PRIOR TO ATTACHING PRESSURE VESSEL

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A parachute system, designed to carry an instrument-laden probe down through the dense atmosphere of torrid, cloud-shrouded Venus, was tested in KSC's Vehicle Assembly Building. The tests are in preparation for a Pioneer multi-probe mission to Venus scheduled for launch from KSC in 1978. Full-scale (12-foot diameter) parachutes with simulated pressure vessels weighing up to 45 pounds were dropped from heights of up to 450 feet tot he floor of the VAB where the impact was cushioned by a honeycomb cardboard impact arrestor. The VAB offers an ideal, wind-free testing facility at no additional construction cost and was used for similar tests of the parachute system for the twin Viking spacecraft scheduled for launch toward Mars in August.

  15. Quantity Distance for the Kennedy Space Center Vehicle Assembly Building for Solid Propellant Fueled Launchers

    NASA Technical Reports Server (NTRS)

    Stover, Steven; Diebler, Corey; Frazier, Wayne

    2006-01-01

    The NASA KSC VAB was built to process Apollo launchers in the 1960's, and later adapted to process Space Shuttles. The VAB has served as a place to assemble solid rocket motors (5RM) and mate them to the vehicle's external fuel tank and Orbiter before rollout to the launch pad. As Space Shuttle is phased out, and new launchers are developed, the VAB may again be adapted to process these new launchers. Current launch vehicle designs call for continued and perhaps increased use of SRM segments; hence, the safe separation distances are in the process of being re-calculated. Cognizant NASA personnel and the solid rocket contractor have revisited the above VAB QD considerations and suggest that it may be revised to allow a greater number of motor segments within the VAB. This revision assumes that an inadvertent ignition of one SRM stack in its High Bay need not cause immediate and complete involvement of boosters that are part of a vehicle in adjacent High Bay. To support this assumption, NASA and contractor personnel proposed a strawman test approach for obtaining subscale data that may be used to develop phenomenological insight and to develop confidence in an analysis model for later use on full-scale situations. A team of subject matter experts in safety and siting of propellants and explosives were assembled to review the subscale test approach and provide options to NASA. Upon deliberations regarding the various options, the team arrived at some preliminary recommendations for NASA.

  16. "Recovery" from the diagnosis of autism - and then?

    PubMed

    Olsson, Martina Barnevik; Westerlund, Joakim; Lundström, Sebastian; Giacobini, MaiBritt; Fernell, Elisabeth; Gillberg, Christopher

    2015-01-01

    The aim of this study was to follow up the 17 children, from a total group of 208 children with autism spectrum disorder (ASD), who "recovered from autism". They had been clinically diagnosed with ASD at or under the age of 4 years. For 2 years thereafter they received intervention based on applied behavior analysis. These 17 children were all of average or borderline intellectual functioning. On the 2-year follow-up assessment, they no longer met criteria for ASD. At about 10 years of age they were targeted for a new follow-up. Parents were given a semistructured interview regarding the child's daily functioning, school situation, and need of support, and were interviewed using the Vineland Adaptive Behavior Scales (VABS) and the Autism - Tics, Attention-deficit/hyperactivity disorder (AD/HD), and other Comorbidities (A-TAC) telephone interview. The vast majority of the children had moderate-to-severe problems with attention/activity regulation, speech and language, behavior, and/or social interaction. A majority of the children had declined in their VABS scores. Most of the 14 children whose parents were A-TAC-interviewed had problems within many behavioral A-TAC domains, and four (29%) had symptom levels corresponding to a clinical diagnosis of ASD, AD/HD, or both. Another seven children (50%) had pronounced subthreshold indicators of ASD, AD/HD, or both. Children diagnosed at 2-4 years of age as suffering from ASD and who, after appropriate intervention for 2 years, no longer met diagnostic criteria for the disorder, clearly needed to be followed up longer. About 3-4 years later, they still had major problems diagnosable under the umbrella term of ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations). They continued to be in need of support, educationally, from a neurodevelopmental and a medical point of view. According to parent interview data, a substantial minority of these children again met diagnostic criteria for ASD.

  17. Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.

    PubMed

    Moler, Frank W; Silverstein, Faye S; Holubkov, Richard; Slomine, Beth S; Christensen, James R; Nadkarni, Vinay M; Meert, Kathleen L; Browning, Brittan; Pemberton, Victoria L; Page, Kent; Gildea, Marianne R; Scholefield, Barnaby R; Shankaran, Seetha; Hutchison, Jamie S; Berger, John T; Ofori-Amanfo, George; Newth, Christopher J L; Topjian, Alexis; Bennett, Kimberly S; Koch, Joshua D; Pham, Nga; Chanani, Nikhil K; Pineda, Jose A; Harrison, Rick; Dalton, Heidi J; Alten, Jeffrey; Schleien, Charles L; Goodman, Denise M; Zimmerman, Jerry J; Bhalala, Utpal S; Schwarz, Adam J; Porter, Melissa B; Shah, Samir; Fink, Ericka L; McQuillen, Patrick; Wu, Theodore; Skellett, Sophie; Thomas, Neal J; Nowak, Jeffrey E; Baines, Paul B; Pappachan, John; Mathur, Mudit; Lloyd, Eric; van der Jagt, Elise W; Dobyns, Emily L; Meyer, Michael T; Sanders, Ronald C; Clark, Amy E; Dean, J Michael

    2017-01-26

    Targeted temperature management is recommended for comatose adults and children after out-of-hospital cardiac arrest; however, data on temperature management after in-hospital cardiac arrest are limited. In a trial conducted at 37 children's hospitals, we compared two temperature interventions in children who had had in-hospital cardiac arrest. Within 6 hours after the return of circulation, comatose children older than 48 hours and younger than 18 years of age were randomly assigned to therapeutic hypothermia (target temperature, 33.0°C) or therapeutic normothermia (target temperature, 36.8°C). The primary efficacy outcome, survival at 12 months after cardiac arrest with a score of 70 or higher on the Vineland Adaptive Behavior Scales, second edition (VABS-II, on which scores range from 20 to 160, with higher scores indicating better function), was evaluated among patients who had had a VABS-II score of at least 70 before the cardiac arrest. The trial was terminated because of futility after 329 patients had undergone randomization. Among the 257 patients who had a VABS-II score of at least 70 before cardiac arrest and who could be evaluated, the rate of the primary efficacy outcome did not differ significantly between the hypothermia group and the normothermia group (36% [48 of 133 patients] and 39% [48 of 124 patients], respectively; relative risk, 0.92; 95% confidence interval [CI], 0.67 to 1.27; P=0.63). Among 317 patients who could be evaluated for change in neurobehavioral function, the change in VABS-II score from baseline to 12 months did not differ significantly between the groups (P=0.70). Among 327 patients who could be evaluated for 1-year survival, the rate of 1-year survival did not differ significantly between the hypothermia group and the normothermia group (49% [81 of 166 patients] and 46% [74 of 161 patients], respectively; relative risk, 1.07; 95% CI, 0.85 to 1.34; P=0.56). The incidences of blood-product use, infection, and serious adverse events, as well as 28-day mortality, did not differ significantly between groups. Among comatose children who survived in-hospital cardiac arrest, therapeutic hypothermia, as compared with therapeutic normothermia, did not confer a significant benefit in survival with a favorable functional outcome at 1 year. (Funded by the National Heart, Lung, and Blood Institute; THAPCA-IH ClinicalTrials.gov number, NCT00880087 .).

  18. KSC-99pp1133

    NASA Image and Video Library

    1999-09-20

    The Butler Building at Kennedy Space Center is nearly demolished, with the help of the crane in the background. The building, which is near the Orbiter Processing Facility (right), is being demolished in order to extend the crawlerway leading to the high bay of the Vehicle Assembly Building (VAB), part of KSC's Safe Haven project. The goal of Safe Haven is to strengthen readiness for Florida's hurricane season by expanding the VAB's storage capacity. Construction includes outfitting the VAB with a third stacking area, in high bay 2, that will allow NASA to preassemble stacks and still have room in the VAB to pull a Shuttle back from the pad into the safety of the VAB if severe weather threatens. The VAB can withstand winds up to 125 mph

  19. KSC-99pp1132

    NASA Image and Video Library

    1999-09-20

    The walls of the Butler Building at Kennedy Space Center come tumbling down, with the help of the crane in the background. The building, which is near the Orbiter Processing Facility, is being demolished in order to extend the crawlerway leading to the high bay of the Vehicle Assembly Building (VAB), part of KSC's Safe Haven project. The goal of Safe Haven is to strengthen readiness for Florida's hurricane season by expanding the VAB's storage capacity. Construction includes outfitting the VAB with a third stacking area, in high bay 2, that will allow NASA to preassemble stacks and still have room in the VAB to pull a Shuttle back from the pad into the safety of the VAB if severe weather threatens. The VAB can withstand winds up to 125 mph

  20. Effects of compositional defects on small polaron hopping in micas.

    PubMed

    Rosso, Kevin M; Ilton, Eugene S

    2005-06-22

    Hartree-Fock calculations and electron transfer (ET) theory were used to model the effects of compositional defects on ET in the brucite-like octahedral sheet of mica. ET was modeled as an Fe(IIIII) valence interchange reaction across shared octahedral edges of the M2-M2 iron sublattice. The model entails the hopping of localized electrons and small polaron behavior. Hartree-Fock calculations indicate that substitution of F for structural OH bridges increases the reorganization energy lambda, decreases the electronic coupling matrix element V(AB), and thereby substantially decreases the hopping rate. The lambda increase arises from modification of the metal-ligand bond force constants, and the V(AB) decrease arises from reduction of superexchange interaction through anion bridges. Deprotonation of an OH bridge, consistent with a possible mechanism of maintaining charge neutrality during net oxidation, yields a net increase in the ET rate. Although substitution of Al or Mg for Fe in M1 sites distorts the structure of adjacent Fe-occupied M2 sites, the distortion has little net impact on ET rates through these M2 sites. Hence the main effect of Al or Mg substitution for Fe, should it occur in the M2 sublattice, is to block ET pathways. Collectively, these findings pave the way for larger-scale oxidation/reduction models to be constructed for realistic, compositionally diverse micas.

  1. Clinical outcomes of interactive, intensive and individual (3i) play therapy for children with ASD: a two-year follow-up study.

    PubMed

    Tilmont Pittala, Elodie; Saint-Georges-Chaumet, Yann; Favrot, Claire; Tanet, Antoine; Cohen, David; Saint-Georges, Catherine

    2018-05-12

    The outcomes of psycho-educational interventions for Autism Spectrum Disorders (ASDs) comorbid with severe to moderate intellectual disability (ID) are insufficiently documented. In this prospective study, we examined a developmental individual, interactive and intensive approach, called the '3i method', which is based on play therapy. Twenty DSM-IV-TR ASD subjects (mean chronological age 63.8 ± 37.8 months; mean developmental age 19.5 ± 6.6 months) were included and followed the 3i method for 24 months. Developmental and behavioural skills were assessed at baseline and after 24 months using the VABS, PEP-R and Nadel Imitation scale. Autism severity was evaluated using the Child Autism Rating Scale (CARS) and the Autism Diagnostic Interview (ADI-R). After 2 years of the 3i method, our 3 primary outcome variables significantly increased (VABS developmental age of socialization increased by 83%, age of communication by 34%, and Nadel Imitation score by 53%). Almost all VABS and PEP-R domains significantly improved. Additionally, increases in the VABS socialization score were positively correlated with the total number of treatment hours and CARS score; all ADI-R areas significantly decreased; and diagnoses had changed in 47.5% of the subjects (37% for PDD-NOS and even 10.5% for ID without PDD). Children who followed the 3i method for 2 years had significantly improved behavioural and developmental skills and showed a clear decrease in autism severity. These results suggest that the 3i method may be useful for autistic children by improving their daily interactions with their social environment. was retrospectively registered on May 20th, 2014 by the French Agency for drug and health (ANSM) under number ID-RCB 2014-A00542-45, reference: B148558-31.

  2. Morphine sensitization as a model of mania: comparative study of the effects of repeated lithium or carbamazepine administration.

    PubMed

    Grappi, Silvia; Marchese, Giovanna; Secci, Maria Elena; De Montis, Maria Graziella; Gambarana, Carla; Scheggi, Simona

    2011-10-01

    Repeated unavoidable stress induces in rats decreased reactivity to avoidable stressors and an anhedonia-like condition that are reverted by long-term antidepressant treatments and regarded as models of core symptoms of depression. Morphine-sensitized rats present resilience to stress-induced behavioral deficits and, if hyporeactivity to stress models a depressive symptom, stress resistance can be regarded as a manic symptom. This hypothesis is supported by the observation that long-term lithium administration reinstates sensitivity to stress in sensitized rats. The first aim of the study was to examine the effects of carbamazepine, a standard antimanic treatment, on the stress resilience of sensitized rats, to further characterize morphine sensitization as a model of manic symptom. Carbamazepine administration abolished stress resilience but did not interfere with the expression of sensitization. The second aim of the study was to assess whether repeated carbamazepine treatment affected the dopaminergic and behavioral responses to a natural reward, a palatable food (vanilla sugar, VS), in non food-deprived sensitized and control rats and compare these possible effects with those of repeated lithium administration. Control and sensitized rats showed increased extraneuronal dopamine levels in the nucleus accumbens shell after VS consumption and competence to acquire an instrumental VS-sustained appetitive behavior (VAB). Repeated carbamazepine treatment abolished the dopaminergic response to VS consumption and disrupted the competence to acquire VAB in control rats. Lithium-treated rats showed a dopaminergic response to VS and easily acquired the appetitive behavior. In sensitized rats, neither carbamazepine nor lithium administration interfered with the dopaminergic response to VS and the acquisition of VAB. In summary, the effect of carbamazepine on the stress resilience of sensitized rats further supported the hypothesis that morphine sensitization might model some symptoms of mania. Moreover, in control rats carbamazepine treatment elicited an anhedonia-like condition that clearly distinguished the effects of this drug from those of lithium. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. KENNEDY SPACE CENTER, FLA. - The external tank in the Vehicle Assembly Building (VAB) is destacked from the solid rocket boosters. The tank and SRBs were configured for Atlantis and mission STS-114. The tank will remain in the VAB.

    NASA Image and Video Library

    2003-05-20

    KENNEDY SPACE CENTER, FLA. - The external tank in the Vehicle Assembly Building (VAB) is destacked from the solid rocket boosters. The tank and SRBs were configured for Atlantis and mission STS-114. The tank will remain in the VAB.

  4. Social-communicative effects of the Picture Exchange Communication System (PECS) in autism spectrum disorders.

    PubMed

    Lerna, Anna; Esposito, Dalila; Conson, Massimiliano; Russo, Luigi; Massagli, Angelo

    2012-01-01

    The Picture Exchange Communication System (PECS) is a common treatment choice for non-verbal children with autism. However, little empirical evidence is available on the usefulness of PECS in treating social-communication impairments in autism. To test the effects of PECS on social-communicative skills in children with autism, concurrently taking into account standardized psychometric data, standardized functional assessment of adaptive behaviour, and information on social-communicative variables coded in an unstructured setting. Eighteen preschool children (mean age = 38.78 months) were assigned to two intervention approaches, i.e. PECS and Conventional Language Therapy (CLT). Both PECS (Phases I-IV) and CLT were delivered three times per week, in 30-min sessions, for 6 months. Outcome measures were the following: Autism Diagnostic Observation Schedule (ADOS) domain scores for Communication and Reciprocal Social Interaction; Language and Personal-Social subscales of the Griffiths' Mental Developmental Scales (GMDS); Communication and Social Abilities domains of the Vineland Adaptive Behavior Scales (VABS); and several social-communicative variables coded in an unstructured setting. Results demonstrated that the two groups did not differ at Time 1 (pre-treatment assessment), whereas at Time 2 (post-test) the PECS group showed a significant improvement with respect to the CLT group on the VABS social domain score and on almost all the social-communicative abilities coded in the unstructured setting (i.e. joint attention, request, initiation, cooperative play, but not eye contact). These findings showed that PECS intervention (Phases I-IV) can improve social-communicative skills in children with autism. This improvement is especially evident in standardized measures of adaptive behaviour and measures derived from the observation of children in an unstructured setting. © 2012 Royal College of Speech and Language Therapists.

  5. [A longitudinal (3 years) study of the development of four children with autism without mental retardation after 90 sessions of social skills training].

    PubMed

    Liratni, M; Blanchet, C; Pry, R

    2016-12-01

    Few studies on social skills training essentially based on ABA techniques are dedicated to children with autism aged 5 to 10 years whereas autistic disorders can be diagnosed in very early childhood. Generally, the main criticisms about these social skills training are: shortness of programs (around 20 sessions), no manual with precise descriptions of sessions and used techniques, and a lack of generalization of the learned skills in everyday life. To describe the evolution (before/after) of symptoms and sociocommunicative skills of 7 children with autism and no mental retardation (mean age=7.08) who participated in 90 sessions (during 3 years) in a learning group of communication and socialization (or LGCS). To develop these sessions, we referred to intellectual and verbal levels obtained by the children on The Wechsler Intelligence Scales. We proposed activities such as open discussion, telling about events or vacations, learning of and communicative social rules, social games, outdoor exercises at home or in parks/shops/supermarkets/restaurants with known/unknown children/adults/sellers. To target the social and communicative skills, we also referred to their intellectual level and to Assessment of basic language and learning skills (ABBLS). To practice these sessions, we referred to: (1) TEACCH cognitive ergonomics principles (Treatment and education of autistic and related communication handicapped children developed by Schopler); and especially (2) ABA techniques (Applied behavior analysis) which are rarely mentioned as such. In particular, we used techniques such as: (a) concrete reinforcements which were frequently evaluated; (b) precise levels of verbal incentives and (c) error corrections. To measure the changes, we assessed children with psychometric tests before and after 90 sessions (ADOS and VABS). The scores show significant improvements in autistic symptoms related to communication (ADOS, P=0.03) and significant improvements in both socialization and communication domains (VABS, P=0.00). From a symptomatic point of view (ADOS), we clinically observe better conversation skills and more social initiatives. About socialization and communication behaviors, parents reported (VABS): better listening, better verbal expression, more social relationships and a start of friendship for most of the children. This three-year longitudinal follow-up is the first known study about the evolution of children with autistic disorders after a great number of sessions of social skills training. It shows that it is possible to adapt social skills training to young children. In addition, our program and our results (VABS) show clear examples of generalization which is targeted as a weakness in the specialized studies. However, the absence of a control group and of a base line strongly limit our results in terms of effectiveness. Copyright © 2016 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  6. Special education versus inclusive education: the role of the TEACCH program.

    PubMed

    Panerai, Simonetta; Zingale, Marinella; Trubia, Grazia; Finocchiaro, Maria; Zuccarello, Rosa; Ferri, Raffaele; Elia, Maurizio

    2009-06-01

    Our study aimed at comparing, over a period of 3 years, the effectiveness of three different educational approaches addressed to children with autism and severe mental retardation. The first one was a treatment and education of autistic and related communication handicapped children (TEACCH) program implemented in a residential center; the second was a TEACCH program implemented at home and at mainstream schools, after a specific parent psychoeducational training; the third approach referred to inclusive education in mainstream schools, in which a nonspecific approach was implemented. Each subject was assessed twice, using the Psycho-Educational Profile-Revised (PEP-R) and Vineland Adaptive Behavior Scale (VABS)-survey form. Effectiveness of TEACCH appeared to be confirmed, showing positive outcomes in the natural setting, and revealing its inclusive value.

  7. Randomized controlled trial of stereotactic 11-G vacuum-assisted core biopsy for the diagnosis and management of mammographic microcalcification

    PubMed Central

    Maxwell, Anthony J; Morris, Julie; Lim, Yit Y; Harake, MD Janick; Whiteside, Sigrid

    2016-01-01

    Objective: To compare the accuracy of 11-G vacuum-assisted biopsy (VAB) with 14-G core needle biopsy (CNB) to diagnose mammographic microcalcification (MM) and effect on surgical outcomes. Methods: Following ethical approval, VAB and CNB (control) were compared in a randomized prospective study for first-line diagnosis of MM and subsequent surgical outcomes in two breast-screening units. Participants gave written informed consent. Exclusions included comorbidity precluding surgery, prior ipsilateral breast cancer and lesions >40 mm requiring mastectomy as first surgical procedure. The final pathological diagnosis was compared with the initial biopsy result. Quality-of-life (QOL) questionnaires were administered at baseline, 2, 6 and 12 months. 110 participants were required to show a 25% improvement in diagnosis with VAB compared with CNB (90% power). Results: Eligibility was assessed for 787 cases; 129 females recalled from the National Health Service breast screening programme were randomized. Diagnostic accuracy of VAB was 86% and that of CNB was 84%. Using VAB, 2/14 (14.3%) cases upgraded from ductal carcinoma in situ to invasion at surgery and 3/19 (15.8%) using CNB. Following VAB 7/16 (44%) cases required repeat surgery vs 7/24 (29%) after CNB. Both groups recorded significant worsening of functional QOL measures and increased breast pain at follow-up. Conclusion: VAB and CNB were equally accurate at diagnosing MM, and no significant differences in surgical outcomes were observed. Advances in knowledge: The first randomized controlled study of VAB for diagnosis of microcalcification using digital mammography showed no difference in diagnostic accuracy of VAB and CNB, or in the proportion of participants needing repeat non-operative biopsy or second therapeutic operation to treat malignancy. PMID:26654214

  8. Adolescent adaptive behavior profiles in Williams-Beuren syndrome, Down syndrome, and autism spectrum disorder.

    PubMed

    Del Cole, Carolina Grego; Caetano, Sheila Cavalcante; Ribeiro, Wagner; Kümmer, Arthur Melo E E; Jackowski, Andrea Parolin

    2017-01-01

    Adaptive behavior can be impaired in different neurodevelopmental disorders and may be influenced by confounding factors, such as intelligence quotient (IQ) and socioeconomic classification. Our main objective was to verify whether adaptive behavior profiles differ in three conditions-Williams Beuren syndrome (WBS), Down syndrome (DS), and autism spectrum disorder (ASD), as compared with healthy controls (HC) and with each other. Although the literature points towards each disorder having a characteristic profile, no study has compared profiles to establish the specificity of each one. A secondary objective was to explore potential interactions between the conditions and socioeconomic status, and whether this had any effect on adaptive behavior profiles. One hundred and five adolescents were included in the study. All adolescents underwent the following evaluations: the Vineland Adaptive Behavior Scale (VABS), the Wechsler Intelligence Scale for Children (WISC), and the Brazilian Economic Classification Criteria. Our results demonstrated that the WBS group performed better than the DS group in the communication domain, β = -15.08, t(3.45), p = .005, and better than the ASD group in the socialization domain, β = 8.92, t(-2.08), p = .013. The DS group also performed better than the ASD group in socialization, β = 16.98, t(-2.32), p = .024. IQ was an important confounding factor, and socioeconomic status had an important effect on the adaptive behavior of all groups. There is a heterogeneity regarding adaptive behavior profiles in WBS, DS, and ASD. These data are important to better design specific strategies related to the health and social care of each particular group.

  9. Evolution of an adaptive behavior and its sensory receptors promotes eye regression in blind cavefish.

    PubMed

    Yoshizawa, Masato; Yamamoto, Yoshiyuki; O'Quin, Kelly E; Jeffery, William R

    2012-12-27

    How and why animals lose eyesight during adaptation to the dark and food-limited cave environment has puzzled biologists since the time of Darwin. More recently, several different adaptive hypotheses have been proposed to explain eye degeneration based on studies in the teleost Astyanax mexicanus, which consists of blind cave-dwelling (cavefish) and sighted surface-dwelling (surface fish) forms. One of these hypotheses is that eye regression is the result of indirect selection for constructive characters that are negatively linked to eye development through the pleiotropic effects of Sonic Hedgehog (SHH) signaling. However, subsequent genetic analyses suggested that other mechanisms also contribute to eye regression in Astyanax cavefish. Here, we introduce a new approach to this problem by investigating the phenotypic and genetic relationships between a suite of non-visual constructive traits and eye regression. Using quantitative genetic analysis of crosses between surface fish, the Pachón cavefish population and their hybrid progeny, we show that the adaptive vibration attraction behavior (VAB) and its sensory receptors, superficial neuromasts (SN) specifically found within the cavefish eye orbit (EO), are genetically correlated with reduced eye size. The quantitative trait loci (QTL) for these three traits form two clusters of congruent or overlapping QTL on Astyanax linkage groups (LG) 2 and 17, but not at the shh locus on LG 13. Ablation of EO SN in cavefish demonstrated a major role for these sensory receptors in VAB expression. Furthermore, experimental induction of eye regression in surface fish via shh overexpression showed that the absence of eyes was insufficient to promote the appearance of VAB or EO SN. We conclude that natural selection for the enhancement of VAB and EO SN indirectly promotes eye regression in the Pachón cavefish population through an antagonistic relationship involving genetic linkage or pleiotropy among the genetic factors underlying these traits. This study demonstrates a trade-off between the evolution of a non-visual sensory system and eye regression during the adaptive evolution of Astyanax to the cave environment.

  10. PIONEER VENUS 2 MULTI-PROBE PARACHUTE TESTS IN THE VEHICLE ASSEMBLY BUILDING

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A parachute system, designed to carry an instrument-laden probe down through the dense atmosphere of torrid, cloud-shrouded Venus, was tested in KSC's Vehicle Assembly Building. The tests are in preparation for a Pioneer multi-probe mission to Venus scheduled for launch from KSC in 1978. Full-scale (12-foot diameter) parachutes with simulated pressure vessels weighing up to 45 pounds were dropped from heights of up to 450 feet tot he floor of the VAB where the impact was cushioned by a honeycomb cardboard impact arrestor. The VAB offers an ideal, wind-free testing facility at no additional construction cost and was used for similar tests of the parachute system for the twin Viking spacecraft scheduled for launch toward Mars in August.

  11. VIEW OF HB1 (VAB HIGH BAY) WITH MOBILE LAUNCHER PLATFORM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF HB-1 (VAB HIGH BAY) WITH MOBILE LAUNCHER PLATFORM (VEHICLE ACCESS PLATFORMS ARE VISIBLE IN THE CENTER), FACING WEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  12. Workers in the VAB move sling into place to lift Columbia to mobile launcher

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Workers in the Vehicle Assembly Building (VAB) move a specially-built sling into place to lift Orbiter Columbia from the transfer aisle to the mobile launcher platform (27015); Columbia is lifted from the floor of the VAB transfer aisle (27016).

  13. VAB Sway Investigation

    NASA Technical Reports Server (NTRS)

    Youngquist, Robert c.; Ihlefeld, Curtis M.; Lane, John E.; Starr, Stanley O.

    2013-01-01

    The Vehicle Assembly Building (VAB) was constructed in the mid-1960s to house the Saturn V moon rocket while it was being assembled. Designed to withstand hurricanes and tropical storms, the V AB has a foundation consisting of 30,000 cubic yards of concrete strengthened by 4,225 steel rods driven 160 feet into limestone bedrock. The goal of the VAB Sway Investigation, which began collecting data in April 201 0 and ended in November 2012, was to quantify the displacement or sway of the VAB as a function of wind loading.

  14. Interdisciplinary consensus on the uses and technique of MR-guided vacuum-assisted breast biopsy (VAB): results of a European consensus meeting.

    PubMed

    Heywang-Köbrunner, Sylvia H; Sinnatamby, Ruchi; Lebeau, Annette; Lebrecht, Antje; Britton, Peter D; Schreer, Ingrid

    2009-11-01

    Quality assurance of MR-guided vacuum-assisted breast biopsy (VAB). A consensus was achieved based on the existing literature and experience of an interdisciplinary group comprising European specialists in breast imaging and VAB. Full imaging work-up must be completed according to existing standards before an indication for MR-guided VAB is established. The procedure should be reserved for lesions demonstrable by MRI alone. Acquisition of >24 cores (11-Gauge) should be routinely attempted, with the intention of sufficiently removing small lesions for accurate diagnosis. Following biopsy the patient should be re-imaged to demonstrate the biopsy site and its proximity to the lesion and hence the likely accuracy of the sampling. All patients should be discussed in a regular interdisciplinary conference and a documented consensus reached regarding patient management. Regular audit and review of all MR-guided VAB results and subsequent follow-up are recommended. This consensus includes protocols for the indication, performance parameters, interdisciplinary interpretation therapeutic recommendation, documentation and follow-up of MR-guided VAB. It does not replace official recommendations for percutaneous biopsy.

  15. Comparison of motor delays in young children with fetal alcohol syndrome to those with prenatal alcohol exposure and with no prenatal alcohol exposure.

    PubMed

    Kalberg, Wendy O; Provost, Beth; Tollison, Sean J; Tabachnick, Barbara G; Robinson, Luther K; Eugene Hoyme, H; Trujillo, Phyllis M; Buckley, David; Aragon, Alfredo S; May, Philip A

    2006-12-01

    Researchers are increasingly considering the importance of motor functioning of children with fetal alcohol spectrum disorder (FASD). The purpose of this study was to assess the motor development of young children with fetal alcohol syndrome (FAS) to determine the presence and degree of delay in their motor skills and to compare their motor development with that of matched children without FAS. The motor development of 14 children ages 20 to 68 months identified with FAS was assessed using the Vineland Adaptive Behavior Scales (VABS). In addition, 2 comparison groups were utilized. Eleven of the children with FAS were matched for chronological age, gender, ethnicity, and communication age to: (1) 11 children with prenatal alcohol exposure who did not have FAS and (2) 11 matched children without any reported prenatal alcohol exposure. The motor scores on the VABS were compared among the 3 groups. Most of the young children with FAS in this study showed clinically important delays in their motor development as measured on the VABS Motor Domain, and their fine motor skills were significantly more delayed than their gross motor skills. In the group comparisons, the young children with FAS had significantly lower Motor Domain standard (MotorSS) scores than the children not exposed to alcohol prenatally. They also had significantly lower Fine Motor Developmental Quotients than the children in both the other groups. No significant group differences were found in gross motor scores. For MotorSS scores and Fine Motor Developmental Quotients, the means and standard errors indicated a continuum in the scores from FAS to prenatal alcohol exposure to nonexposure. These findings strongly suggest that all young children with FAS should receive complete developmental evaluations that include assessment of their motor functioning, to identify problem areas and provide access to developmental intervention programs that target deficit areas such as fine motor skills. Fine motor delays in children with FAS may be related to specific neurobehavioral deficits that affect fine motor skills. The findings support the concept of an FASD continuum in some areas of motor development.

  16. The autistic phenotype in Down syndrome: differences in adaptive behaviour versus Down syndrome alone and autistic disorder alone.

    PubMed

    Dressler, Anastasia; Perelli, Valentina; Bozza, Margherita; Bargagna, Stefania

    2011-01-01

    The autistic phenotype in Down syndrome (DS) is marked by a characteristic pattern of stereotypies, anxiety and social withdrawal. Our aim was to study adaptive behaviour in DS with and without autistic comorbidity using the Vineland Adaptive Behaviour Scales (VABS), the Childhood Autism Rating Scales (CARS) and the DSM IV-TR criteria. We assessed 24 individuals and established three groups: Down syndrome (DS), DS and autistic disorder (DS-AD), and autistic disorder (AD). The DS and DS-AD groups showed statistically significantly similar strengths on the VABS (in receptive and domestic skills). The DS and DS-AD subjects also showed similar strengths on the CARS (in imitation and relating), differing significantly from the AD group. The profile of adaptive functioning and symptoms in DS-AD seemed to be more similar to that found in DS than to the profile emerging in AD. We suggest that the comorbidity of austistic symptoms in DS hampered the acquisition of adaptive skills more than did the presence of DS alone.

  17. The autistic phenotype in Down syndrome: differences in adaptive behaviour versus Down syndrome alone and autistic disorder alone

    PubMed Central

    Dressler, Anastasia; Perelli, Valentina; Bozza, Margherita; Bargagna, Stefania

    Summary The autistic phenotype in Down syndrome (DS) is marked by a characteristic pattern of stereotypies, anxiety and social withdrawal. Our aim was to study adaptive behaviour in DS with and without autistic comorbidity using the Vineland Adaptive Behaviour Scales (VABS), the Childhood Autism Rating Scales (CARS) and the DSM IV-TR criteria. We assessed 24 individuals and established three groups: Down syndrome (DS), DS and autistic disorder (DS-AD), and autistic disorder (AD). The DS and DS-AD groups showed statistically significantly similar strengths on the VABS (in receptive and domestic skills). The DS and DS-AD subjects also showed similar strengths on the CARS (in imitation and relating), differing significantly from the AD group. The profile of adaptive functioning and symptoms in DS-AD seemed to be more similar to that found in DS than to the profile emerging in AD. We suggest that the comorbidity of austistic symptoms in DS hampered the acquisition of adaptive skills more than did the presence of DS alone. PMID:22152436

  18. KSC-98pc1238

    NASA Image and Video Library

    1998-09-21

    KENNEDY SPACE CENTER, FLA. -- Looking eastward, the Vehicle Assembly Building (VAB) in the Launch Complex 39 area can be seen with its new coat of paint, along with newly painted American flag and NASA logo. The improved look was finished in time to honor NASA's 40th anniversary on Oct. 1. In order to do the job, workers were suspended on platforms from the top of the 525-foot-high VAB. One of the world's largest buildings by volume, the VAB is the last stop for the Shuttle before rollout to the launch pad. Integration and stacking of the complete Space Shuttle vehicle (orbiter, two solid rocket boosters and the external tank) takes place in High Bays 1 or 3. Stretching from the side of the VAB, on the right, is the crawlerway, used to transport the Space Shuttle to the launch pad. Beyond the VAB is Banana Creek

  19. Photocopy of drawing. VAB HB2 & 4 ET HOLDING CELLS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VAB HB-2 & 4 ET HOLDING CELLS, UPGRADE TO CHECKOUT CELLS. NASA John F. Kennedy Space Center, Florida. File Number 79K33180, Reynolds, Smith & Hill, February 1991. GENERAL ARRANGEMENT, PLAN & ELEVATIONS. Sheet 4 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  20. Photocopy of drawing. VAB HB2 & 4 ET HOLDING CELLS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VAB HB-2 & 4 ET HOLDING CELLS, UPGRADE TO CHECKOUT CELLS. NASA John F. Kennedy Space Center, Florida. File Number 79K33180, Reynolds, Smith & Hill, February 1991. HINGED PANEL EQUIPMENT SCHEDULE. Sheet 28 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  1. Total cost comparison of 2 biopsy methods for nonpalpable breast lesions.

    PubMed

    Bodai, B I; Boyd, B; Brown, L; Wadley, H; Zannis, V J; Holzman, M

    2001-05-01

    To identify, quantify, and compare total facility costs for 2 breast biopsy methods: vacuum-assisted biopsy (VAB) and needle-wire-localized open surgical biopsy (OSB). A time-and-motion study was done to identify unit resources used in both procedures. Costs were imputed from published literature to value resources. A comparison of the total (fixed and variable) costs of the 2 procedures was done. A convenience sample of 2 high-volume breast biopsy (both VAB and OSB) facilities was identified. A third facility (OSB only) and 8 other sites (VAB only) were used to capture variation. Staff interviews, patient medical records, and billing data were used to check observed data. One hundred and sixty-seven uncomplicated procedures (71 OSBs, 96 VABs) were observed. Available demographic and clinical data were analyzed to assess selection bias, and sensitivity analyses were done on the main assumptions. The total facility costs of the VAB procedure were lower than the costs of the OSB procedure. The overall cost advantage for using VAB ranges from $314 to $843 per procedure depending on the facility type. Variable cost comparison indicated little difference between the 2 procedures. The largest fixed cost difference was $763. Facilities must consider the cost of new technology, especially when the new technology is as effective as the present technology. The seemingly high cost of equipment might negatively influence a decision to adopt VAB, but when total facility costs were analyzed, the new technology was less costly.

  2. Photocopy of drawing. VAB HB2 & 4 ET HOLDING CELLS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VAB HB-2 & 4 ET HOLDING CELLS, UPGRADE TO CHECKOUT CELLS. NASA John F. Kennedy Space Center, Florida. File Number 79K33180, Reynolds, Smith & Hill, February 1991. H.B.-2, PLANS AT LEVELS 4,5,&6. Sheet 7 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  3. Photocopy of drawing. VAB HB2 & 4 ET HOLDING CELLS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VAB HB-2 & 4 ET HOLDING CELLS, UPGRADE TO CHECKOUT CELLS. NASA John F. Kennedy Space Center, Florida. File Number 79K33180, Reynolds, Smith & Hill, February 1991. H.B.-2, PLANS AT LEVELS 1,2,&3. Sheet 6 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  4. Photocopy of drawing. VAB HB2 & 4 ET HOLDING CELLS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VAB HB-2 & 4 ET HOLDING CELLS, UPGRADE TO CHECKOUT CELLS. NASA John F. Kennedy Space Center, Florida. File Number 79K33180, Reynolds, Smith & Hill, February 1991. H.B.-2, PLANS AT LEVELS 7,8,&9. Sheet 8 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  5. Deletion 2q37 syndrome: Cognitive-behavioral trajectories and autistic features related to breakpoint and deletion size.

    PubMed

    Fisch, Gene S; Falk, Rena E; Carey, John C; Imitola, Jaime; Sederberg, Maria; Caravalho, Karen S; South, Sarah

    2016-09-01

    Subtelomeric deletions have been reported in ∼2.5% of individuals with developmental disabilities. Subtelomeric deletion 2q37 has been detected in many individuals diagnosed with intellectual disabilities (ID) and autism spectrum disorders (ASD). Previously, genotype-phenotype correspondences were examined for their relationship to breakpoints 37.1, 37.2, or 37.3. Our purpose was to ascertain whether there were phenotypic differences at these breakpoints, elucidate the cognitive-behavioral phenotype in del2q37, and examine the genotype-phenotype association in the deletion with respect to cognitive-behavioral profiles and ASD. We administered a comprehensive cognitive-behavioral battery to nine children diagnosed with del 2q37, ages 3.9-17.75 years. ID for five tested with the Stanford-Binet (4th Edition) (SBFE) ranged from severe to mild [IQ Range: 36-59]. Adaptive behavior scores from the Vineland Adaptive Behavior Scale (VABS) were much below adequate levels (DQ Range: floor value ["19"] to 55). Autism scores from the Child Autism Rating Scale (CARS) ranged from 22 [non-autistic] to 56 [extremely autistic]; 5/8 [63%] children received scores on the autism spectrum. Participants with the largest deletions, 10.1 and 9.5 Mb, attained the highest IQ and DQ scores while those with the smallest deletions, 7.9 and 6.6 Mb, made the lowest IQ and DQ scores. No association between deletion breakpoint and phenotype were found. Assessment of the various deleted regions suggested histone deacetylase 4 gene (HDAC4) was a likely candidate gene for ASD in our sample. However, two earlier reports found no association between HDAC4 haploinsufficiency and ASD. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  6. KSC-2011-1449

    NASA Image and Video Library

    2011-02-15

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, workers receive training atop a mast climber that is attached to launch simulation towers outside the Launch Equipment Test Facility. The training includes attaching carrier plates, water and air systems, and electricity to the climber to simulate working in Kennedy's Vehicle Assembly Building (VAB). Mast climbers can be substituted for fixed service structures currently inside the VAB to provide access to any type of launch vehicle. Since 1977, the facility has supported NASA’s Launch Services, shuttle, International Space Station, and Constellation programs, as well as commercial providers. Last year, the facility underwent a major upgrade to support even more programs, projects and customers. It houses a 6,000-square-foot high bay, cable fabrication and molding shop, pneumatics shop, machine and weld shop and full-scale control room. Outside, the facility features a water flow test loop, vehicle motion simulator and a cryogenic system. Photo credit: NASA/Jim Grossmann

  7. KSC-2011-1446

    NASA Image and Video Library

    2011-02-15

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, workers receive training atop a mast climber that is attached to launch simulation towers outside the Launch Equipment Test Facility. The training includes attaching carrier plates, water and air systems, and electricity to the climber to simulate working in Kennedy's Vehicle Assembly Building (VAB). Mast climbers can be substituted for fixed service structures currently inside the VAB to provide access to any type of launch vehicle. Since 1977, the facility has supported NASA’s Launch Services, shuttle, International Space Station, and Constellation programs, as well as commercial providers. Last year, the facility underwent a major upgrade to support even more programs, projects and customers. It houses a 6,000-square-foot high bay, cable fabrication and molding shop, pneumatics shop, machine and weld shop and full-scale control room. Outside, the facility features a water flow test loop, vehicle motion simulator and a cryogenic system. Photo credit: NASA/Jim Grossmann

  8. KSC-2011-1450

    NASA Image and Video Library

    2011-02-15

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, training takes place atop a mast climber that is attached to launch simulation towers outside the Launch Equipment Test Facility. The training includes attaching carrier plates, water and air systems, and electricity to the climber to simulate working in Kennedy's Vehicle Assembly Building (VAB). Mast climbers can be substituted for fixed service structures currently inside the VAB to provide access to any type of launch vehicle. Since 1977, the facility has supported NASA’s Launch Services, shuttle, International Space Station, and Constellation programs, as well as commercial providers. Last year, the facility underwent a major upgrade to support even more programs, projects and customers. It houses a 6,000-square-foot high bay, cable fabrication and molding shop, pneumatics shop, machine and weld shop and full-scale control room. Outside, the facility features a water flow test loop, vehicle motion simulator and a cryogenic system. Photo credit: NASA/Jim Grossmann

  9. KSC-2011-1448

    NASA Image and Video Library

    2011-02-15

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, workers receive training atop a mast climber that is attached to launch simulation towers outside the Launch Equipment Test Facility. The training includes attaching carrier plates, water and air systems, and electricity to the climber to simulate working in Kennedy's Vehicle Assembly Building (VAB). Mast climbers can be substituted for fixed service structures currently inside the VAB to provide access to any type of launch vehicle. Since 1977, the facility has supported NASA’s Launch Services, shuttle, International Space Station, and Constellation programs, as well as commercial providers. Last year, the facility underwent a major upgrade to support even more programs, projects and customers. It houses a 6,000-square-foot high bay, cable fabrication and molding shop, pneumatics shop, machine and weld shop and full-scale control room. Outside, the facility features a water flow test loop, vehicle motion simulator and a cryogenic system. Photo credit: NASA/Jim Grossmann

  10. KSC-2011-1447

    NASA Image and Video Library

    2011-02-15

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, workers receive training on a mast climber that is attached to launch simulation towers outside the Launch Equipment Test Facility. The training includes attaching carrier plates, water and air systems, and electricity to the climber to simulate working in Kennedy's Vehicle Assembly Building (VAB). Mast climbers can be substituted for fixed service structures currently inside the VAB to provide access to any type of launch vehicle. Since 1977, the facility has supported NASA’s Launch Services, shuttle, International Space Station, and Constellation programs, as well as commercial providers. Last year, the facility underwent a major upgrade to support even more programs, projects and customers. It houses a 6,000-square-foot high bay, cable fabrication and molding shop, pneumatics shop, machine and weld shop and full-scale control room. Outside, the facility features a water flow test loop, vehicle motion simulator and a cryogenic system. Photo credit: NASA/Jim Grossmann

  11. Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skills.

    PubMed

    Yirmiya, N; Rosenberg, C; Levi, S; Salomon, S; Shulman, C; Nemanov, L; Dina, C; Ebstein, R P

    2006-05-01

    We examined three microsatellites in the arginine vasopressin 1a receptor gene (AVPR1a), two in the promoter region (RS1 and RS3) and an intronic microsatellite (AVR), for association with autism as well as scores on the Vineland Adaptive Behavior Scale (VABS), the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Scale-Generic (ADOS-G), measures that are widely used to diagnose autism spectrum disorders. We tested for association between the AVPR1a microsatellites and autism in 116 families (128 probands diagnosed with the ADI-R and ADOS-G using a family-based association test (UNPHASED)). Testing each individual microsatellite showed significant transmission disequilibrium in these families with the AVR intronic microsatellite (UNPHASED: LRS=11.46, global P-value=0.009, df=3). Haplotype analysis of three microsatellites also showed significant association (LRS=144.94, df=103, global P=0.004). Additionally, significant association is observed between these three microsatellite haplotypes and the VABS scores (P=0.009), with the ADI-R (P=0.009) and the ADOS-G (P=0.0000765) diagnoses of autistic disorder versus pervasive developmental disorder-not otherwise specified (PDD-NOS) that were available for 47 of these probands. This is the third consecutive report of an association between the AVPR1a gene and autism spectrum disorders and in the current study a third microsatellite is shown to be associated with autism spectrum disorders as well as haplotypes consisting of all three markers. Importantly, the association appears to be mainly mediated by the role of the AVPR1a gene in shaping socialization skills, similar to its role in lower vertebrates.Molecular Psychiatry (2006) 11, 488-494. doi:10.1038/sj.mp.4001812; published online 7 March 2006.

  12. STS-106 orbiter Atlantis rolls over to the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The orbiter Atlantis heads toward the open door of the Vehicle Assembly Building (VAB) on the north side. In the VAB it will be lifted to vertical and placed aboard the mobile launcher platform (MLP) for stacking with the solid rocket boosters and external tank. Atlantis is scheduled to launch Sept. 8 on mission STS-106, the fourth construction flight to the International Space Station, with a crew of seven.

  13. Ultrasound-guided cable-free 13-gauge vacuum-assisted biopsy of non-mass breast lesions

    PubMed Central

    Seo, Jiwoon; Jang, Mijung; Yun, Bo La; Lee, Soo Hyun; Kim, Eun-Kyu; Kang, Eunyoung; Park, So Yeon; Moon, Woo Kyung; Choi, Hye Young; Kim, Bohyoung

    2017-01-01

    Purpose To compare the outcomes of ultrasound-guided core biopsy for non-mass breast lesions by the novel 13-gauge cable-free vacuum-assisted biopsy (VAB) and by the conventional 14-gauge semi-automated core needle biopsy (CCNB). Materials and methods Our institutional review board approved this prospective study, and all patients provided written informed consent. Among 1840 ultrasound-guided percutaneous biopsies performed from August 2013 to December 2014, 145 non-mass breast lesions with suspicious microcalcifications on mammography or corresponding magnetic resonance imaging finding were subjected to 13-gauge VAB or 14-gauge CCNB. We evaluated the technical success rates, average specimen numbers, and tissue sampling time. We also compared the results of percutaneous biopsy and final surgical pathologic diagnosis to analyze the rates of diagnostic upgrade or downgrade. Results Ultrasound-guided VAB successfully targeted and sampled all lesions, whereas CCNB failed to demonstrate calcification in four (10.3%) breast lesions with microcalcification on specimen mammography. The mean sampling time were 238.6 and 170.6 seconds for VAB and CCNB, respectively. No major complications were observed with either method. Ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia (ADH) lesions were more frequently upgraded after CCNB (8/23 and 3/5, respectively) than after VAB (2/26 and 0/4, respectively P = 0.028). Conclusion Non-mass breast lesions were successfully and accurately biopsied using cable-free VAB. The underestimation rate of ultrasound-detected non-mass lesion was significantly lower with VAB than with CCNB. Trial registration CRiS KCT0002267. PMID:28628656

  14. Chest wall mechanics in sustained microgravity

    NASA Technical Reports Server (NTRS)

    Wantier, M.; Estenne, M.; Verbanck, S.; Prisk, G. K.; Paiva, M.; West, J. B. (Principal Investigator)

    1998-01-01

    We assessed the effects of sustained weightlessness on chest wall mechanics in five astronauts who were studied before, during, and after the 10-day Spacelab D-2 mission (n = 3) and the 180-day Euromir-95 mission (n = 2). We measured flow and pressure at the mouth and rib cage and abdominal volumes during resting breathing and during a relaxation maneuver from midinspiratory capacity to functional residual capacity. Microgravity produced marked and consistent changes (Delta) in the contribution of the abdomen to tidal volume [DeltaVab/(DeltaVab + DeltaVrc), where Vab is abdominal volume and Vrc is rib cage volume], which increased from 30.7 +/- 3. 5 (SE)% at 1 G head-to-foot acceleration to 58.3 +/- 5.7% at 0 G head-to-foot acceleration (P < 0.005). Values of DeltaVab/(DeltaVab + DeltaVrc) did not change significantly during the 180 days of the Euromir mission, but in the two subjects DeltaVab/(DeltaVab + DeltaVrc) was greater on postflight day 1 than on subsequent postflight days or preflight. In the two subjects who produced satisfactory relaxation maneuvers, the slope of the Konno-Mead plot decreased in microgravity; this decrease was entirely accounted for by an increase in abdominal compliance because rib cage compliance did not change. These alterations are similar to those previously reported during short periods of weightlessness inside aircrafts flying parabolic trajectories. They are also qualitatively similar to those observed on going from upright to supine posture; however, in contrast to microgravity, such postural change reduces rib cage compliance.

  15. View of VAB from Mobile Launcher

    NASA Image and Video Library

    2017-03-13

    A view of the north side of the Vehicle Assembly Building (VAB) from the top of the mobile launcher tower at NASA's Kennedy Space Center in Florida. Inside the VAB, 10 levels of platforms, 20 platform halves altogether, have been installed in High Bay 3. The platforms will surround NASA's Space Launch System (SLS) rocket and the Orion spacecraft and allow access during processing for missions, including the first uncrewed flight test of Orion atop the SLS rocket in 2018. Crawler-transporter 2 will carry the rocket and spacecraft atop the mobile launcher to Launch Pad 39B for Exploration Mission 1. The Ground Systems Development and Operations Program, with support from the center's Engineering Directorate, is overseeing upgrades and modifications to the VAB and the mobile launcher.

  16. Recommendations for Safe Separation Distances from the Kennedy Space Center (KSC) Vehicle Assembly Building (VAB) Using a Heat-Flux-Based Analytical Approach (Abridged)

    NASA Technical Reports Server (NTRS)

    Cragg, Clinton H.; Bowman, Howard; Wilson, John E.

    2011-01-01

    The NASA Engineering and Safety Center (NESC) was requested to provide computational modeling to support the establishment of a safe separation distance surrounding the Kennedy Space Center (KSC) Vehicle Assembly Building (VAB). The two major objectives of the study were 1) establish a methodology based on thermal flux to determine safe separation distances from the Kennedy Space Center's (KSC's) Vehicle Assembly Building (VAB) with large numbers of solid propellant boosters containing hazard division 1.3 classification propellants, in case of inadvertent ignition; and 2) apply this methodology to the consideration of housing eight 5-segment solid propellant boosters in the VAB. The results of the study are contained in this report.

  17. Brief Report: Adaptive Functioning in Children with ASD, ADHD and ASD + ADHD

    ERIC Educational Resources Information Center

    Ashwood, Karen L.; Tye, Charlotte; Azadi, Bahare; Cartwright, Sally; Asherson, Philip; Bolton, Patrick

    2015-01-01

    Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) often co-occur. Children with ASD and ADHD demonstrate deficits in adaptive functioning, yet pure and comorbid groups have not been directly compared. Vineland Adaptive Behaviour Scales (VABS-II) data were examined in boys with ASD (n = 17), ADHD (n = 31) and…

  18. Phthalate concentrations in house dust in relation to autism spectrum disorder and developmental delay in the CHildhood Autism Risks from Genetics and the Environment (CHARGE) study.

    PubMed

    Philippat, Claire; Bennett, Deborah H; Krakowiak, Paula; Rose, Melissa; Hwang, Hyun-Min; Hertz-Picciotto, Irva

    2015-06-26

    Phthalates are endocrine-disrupting chemicals that influence thyroid hormones and sex steroids, both critical for brain development. We studied phthalate concentrations in house dust in relation to the risks of developing autism spectrum disorder (ASD) or developmental delay (DD). Participants were a subset of children from the CHARGE (CHildhood Autism Risks from Genetics and the Environment) case-control study. ASD and DD cases were identified through the California Department of Developmental Services system or referrals; general population controls were randomly sampled from state birth files and frequency-matched on age, sex, and broad geographic region to ASD cases. All children (50 ASD, 27 DD, 68 typically developing (TD)) were assessed with Mullen Scales of Early Learning, Vineland Adaptive Behavior Scales (VABS) and Aberrant Behavior Checklist. We measured 5 phthalates in dust collected in the child's home using a high volume small surface sampler. None of the phthalates measured in dust was associated with ASD. After adjustment, we observed greater di(2-ethylhexyl) phthalate (DEHP) and butylbenzyl phthalate (BBzP) concentrations in indoor dust from homes of DD children: Odds ratios (OR) were 2.10 (95% confidence interval (CI); 1.10; 4.09) and 1.40 (95% CI; 0.97; 2.04) for a one-unit increase in the ln-transformed DEHP and BBzP concentrations, respectively. Among TD children, VABS communication, daily living, and adaptive composite standard scores were lower, in association with increased diethyl phthalate (DEP) concentrations in dust. Participants with higher dibutyl phthalate (DBP) concentrations in house dust also trended toward reduced performance on these subscales. Among ASD and DD boys, higher indoor dust concentrations of DEP and DBP were associated with greater hyperactivity-impulsivity and inattention. House dust levels of phthalates were not associated with ASD. The inability to distinguish past from recent exposures in house dust and the fact that house dust does not capture exposure from all sources, limit the interpretation of both positive and null findings and further work is needed. However, the associations observed for DEP and DBP with impairments in several adaptive functions and greater hyperactivity, along with evidence for increased risk of DD raise concerns that these chemicals may affect neurodevelopment in children.

  19. A comparison of diagnostic performance of vacuum-assisted biopsy and core needle biopsy for breast microcalcification: a systematic review and meta-analysis.

    PubMed

    Huang, Xu Chen; Hu, Xu Hua; Wang, Xiao Ran; Zhou, Chao Xi; Wang, Fei Fei; Yang, Shan; Wang, Gui Ying

    2018-03-16

    Core needle biopsy (CNB) and vacuum-assisted biopsy (VAB) are both popularly used breast percutaneous biopsies. Both of them have become reliable alternatives to open surgical biopsy (OSB) for breast microcalcification (BM). It is controversial that which biopsy method is more accurate and safer for BM. Hence, we conducted this meta-analysis to compare the diagnostic performance between CNB and VAB for BM, aiming to find out the better method. Articles according with including and excluding criteria were collected from the databases, PubMed, Embase, and the Cochrane Library. Preset outcomes were abstracted and pooled to find out the potential advantages in CNB or VAB. Seven studies were identified and entered final meta-analysis from initially found 138 studies. The rate of ductal carcinoma in situ (DCIS) underestimation was significantly lower in VAB than CNB group [risk ratio (RR) = 1.83, 95% confidence interval (CI) 1.40 to 2.40, p < 0.001]. The microcalcification retrieval rate was significantly higher in VAB than CNB group (RR = 0.89, 95% CI 0.81 to 0.98, p = 0.02), while CNB owned a significantly lower complication rate than VAB (RR = 0.18, 95% CI 0.03 to 0.93, p = 0.04). The atypical ductal hyperplasia (ADH) underestimation rates were not compared for the limited number of studies reporting this outcome. Compared with CNB, VAB shows better diagnostic performance in DCIS underestimation rate and microcalcification retrieval rate. However, CNB shows a significantly lower complication rate. More studies are needed to verify these findings.

  20. An external tank is moved from a barge in the turn basin to the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    A newly arrived external tank is transported from the turn basin to the Vehicle Assembly Building (VAB), seen behind the tank. External tanks are built by the NASA Michoud Assembly Facility in New Orleans and transported by barge to Cape Canaveral and then up the Banana River to the turn basin in the Launch Complex 39 Area. In the VAB, the tank will await stacking for a future Shuttle mission.

  1. An external tank is moved from a barge in the turn basin to the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    A newly arrived external tank heads from the turn basin toward the Vehicle Assembly Building (VAB), seen behind the tank. External tanks are built by the NASA Michoud Assembly Facility in New Orleans and transported by barge to Cape Canaveral and then up the Banana River to the turn basin in the Launch Complex 39 Area. In the VAB, the tank will await stacking for a future Shuttle mission.

  2. A Century after Van Allen's Birth: Conclusion of Reconnaissance of Radiation Belts in the Solar System

    NASA Astrophysics Data System (ADS)

    Krimigis, S. M.

    2014-12-01

    On May 1, 1958 in the Great Hall of the US National Academy of Sciences, James A. Van Allen, having instrumented Explorer-1 and follow-on satellites with radiation detectors, announced the discovery of intense radiation at high altitudes above Earth. The press dubbed the doughnut-shaped structures "Van Allen Belts" (VAB). Soon thereafter, the search began for VAB at nearby planets. Mariner 2 flew by Venus in 1962 at a distance of 41,000 km, but no radiation was detected. The Mariner 4 mission to Mars did not observe planet-associated increase in radiation, but scaling arguments with Earth's magnetosphere yielded an upper limit to the ratio of magnetic moments of MM/ME < 0.001 (Van Allen et al, 1965). Similarly, the Mariner 5 flyby closer to Venus resulted in a ratio of magnetic moments < 0.001 (Van Allen et al, 1967), dealing a blow to the expectation that all planetary bodies must possess significant VAB. The flyby of Mercury in 1974 by Mariner 10 revealed a weak magnetic field, but the presence of durably trapped higher energy particles remained controversial until MESSENGER in 2011.The first flybys of Jupiter by Pioneers 10, 11 in 1973 and 1974, respectively, measured a plethora of energetic particles in Jupiter's magnetosphere and established the fact that their intensities were rotationally modulated. Later flybys of Jupiter and Saturn by the two Voyagers in 1979 and 1981 revealed that those magnetospheres possessed their own internal plasma source(s) and radiation belts. Subsequent discoveries of Van Allen belts at Uranus and Neptune by Voyager 2 demonstrated that VAB are the rule rather than the exception in planetary environments. We now know from the Voyagers and through Energetic Neutral Atom images from Cassini and IBEX that an immense energetic particle population surrounds the heliosphere itself. Thus, the reconnaissance of radiation belts of our solar system has been completed, some 56 years after the discovery of the Van Allen Belts at Earth.

  3. STS-106 orbiter Atlantis rolls over to the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The orbiter Atlantis is moved aboard an orbiter transporter from the Orbiter Processing Facility (OPF) bay 3 over to the Vehicle Assembly Building (VAB). In the background (right) are OPF bays 1 and 2. In the VAB it will be lifted to vertical and placed aboard the mobile launcher platform (MLP) for stacking with the solid rocket boosters and external tank. Atlantis is scheduled to launch Sept. 8 on mission STS-106, the fourth construction flight to the International Space Station, with a crew of seven.

  4. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    The Orion heat shield from Exploration Flight Test-1, secured on a transporter, arrives at the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The heat shield was moved from the Launch Abort System Facility. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  5. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    The Orion heat shield from Exploration Flight Test-1 has arrived in High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The heat shield was moved from the Launch Abort System Facility. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  6. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    Inside the Launch Abort System Facility at NASA's Kennedy Space Center in Florida, the Orion heat shield from Exploration Flight Test-1 is secured on a transporter and ready for its move to the Vehicle Assembly Building (VAB). The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  7. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    Inside the Launch Abort System Facility at NASA's Kennedy Space Center in Florida, the Orion heat shield from Exploration Flight Test-1 is being loaded onto a transporter for its move to the Vehicle Assembly Building (VAB). The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  8. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    Inside the Launch Abort System Facility at NASA's Kennedy Space Center in Florida, a crane lowers the Orion heat shield from Exploration Flight Test-1 onto a transporter for its move to the Vehicle Assembly Building (VAB). The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  9. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    The Orion heat shield from Exploration Flight Test-1, secured on a transporter, departs the Launch Abort System Facility at NASA's Kennedy Space Center in Florida, for its move to the Vehicle Assembly Building (VAB). The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  10. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    Inside the Launch Abort System Facility at NASA's Kennedy Space Center in Florida, the Orion heat shield from Exploration Flight Test-1 is being prepared for its move to the Vehicle Assembly Building (VAB). The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  11. STS-106 orbiter Atlantis rolls over to the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    KSC employees accompany the orbiter Atlantis as it is moved aboard an orbiter transporter to the Vehicle Assembly Building (VAB). In the background are OPF bays 1 and 2. In the VAB it will be lifted to vertical and placed aboard the mobile launcher platform (MLP) for stacking with the solid rocket boosters and external tank. Atlantis is scheduled to launch Sept. 8 on mission STS-106, the fourth construction flight to the International Space Station, with a crew of seven.

  12. STS-106 orbiter Atlantis rolls over to the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Viewed from an upper level in the Vehicle Assembly Building (VAB), the orbiter Atlantis waits in the transfer aisle after its move from the Orbiter Processing Facility. In the VAB it will be lifted to vertical and placed aboard the mobile launcher platform (MLP) for stacking with the solid rocket boosters and external tank. Atlantis is scheduled to launch Sept. 8 on mission STS-106, the fourth construction flight to the International Space Station, with a crew of seven.

  13. KENNEDY SPACE CENTER, FLA. - Flatbed trucks carrying some of the debris of Space Shuttle Columbia approach the Vehicle Assembly Building (VAB). The debris is being transferred from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

    NASA Image and Video Library

    2003-09-15

    KENNEDY SPACE CENTER, FLA. - Flatbed trucks carrying some of the debris of Space Shuttle Columbia approach the Vehicle Assembly Building (VAB). The debris is being transferred from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

  14. KENNEDY SPACE CENTER, FLA. - Pieces of Columbia debris are offloaded from a flatbed truck in the transfer aisle of the Vehicle Assembly Building (VAB). The debris is being moved from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

    NASA Image and Video Library

    2003-09-15

    KENNEDY SPACE CENTER, FLA. - Pieces of Columbia debris are offloaded from a flatbed truck in the transfer aisle of the Vehicle Assembly Building (VAB). The debris is being moved from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

  15. Aerial photo shows Launch Complex 39 Area

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This aerial photo shows the areas recently opened as part of KSC's Safe Haven project. The curved road in the center is the newly restored crawlerway leading around the Vehicle Assembly Building (VAB) and Orbiter Processing Facility 3 (OPF-3) into the VAB high bay 2 (open on the lower right), where a mobile launcher platform/crawler-transporter currently sits. The Safe Haven project will enable the storage of orbiters during severe weather. OPF1 and OPF-2 are at the lower right. The crawlerway also extends from the east side of the VAB out to the two launch pads. Launch Pad 39A is visible to the left of the crawlerway. In the distance is the Atlantic Ocean. To the right of the VAB is the turn basin, into which ships tow the barge for offloading new external tanks from Louisiana.

  16. Repainting of the VAB continues

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The American flag is being repainted on the side of the Vehicle Assembly Building (VAB). The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. In addition to the flag, the NASA logo, also known as the 'meatball,' is being painted on the VAB. When finished, the logo will measure 110 feet by 132 feet, or about 12,300 square feet. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September.

  17. Repainting of the VAB continues

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Painters are dwarfed by the six-foot stars in the blue field of the American flag they are repainting on the side of the Vehicle Assembly Building (VAB). The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. In addition to the flag, the NASA logo, also known as the 'meatball,' is being painted on the VAB. When finished, the logo will measure 110 feet by 132 feet, or about 12,300 square feet. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September.

  18. Repainting of the VAB continues

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The NASA logo, also known as the 'meatball,' is painted on the side of the Vehicle Assembly Building (VAB). When finished, the logo will measure 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525- foot-high VAB, are using rollers and brushes to do the painting. In addition to the logo, the American flag is also being repainted on the other side of the VAB. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid- September.

  19. KENNEDY SPACE CENTER, FLA. - A worker moves some of the Columbia debris to its storage site in the Vehicle Assembly Building (VAB). The debris is being transferred from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

    NASA Image and Video Library

    2003-09-15

    KENNEDY SPACE CENTER, FLA. - A worker moves some of the Columbia debris to its storage site in the Vehicle Assembly Building (VAB). The debris is being transferred from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

  20. KENNEDY SPACE CENTER, FLA. - Workers move some of the Columbia debris to its storage site in the Vehicle Assembly Building (VAB). The debris is being transferred from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

    NASA Image and Video Library

    2003-09-15

    KENNEDY SPACE CENTER, FLA. - Workers move some of the Columbia debris to its storage site in the Vehicle Assembly Building (VAB). The debris is being transferred from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

  1. Composite Beam Theory with Material Nonlinearities and Progressive Damage

    NASA Astrophysics Data System (ADS)

    Jiang, Fang

    Beam has historically found its broad applications. Nowadays, many engineering constructions still rely on this type of structure which could be made of anisotropic and heterogeneous materials. These applications motivate the development of beam theory in which the impact of material nonlinearities and damage on the global constitutive behavior has been a focus in recent years. Reliable predictions of these nonlinear beam responses depend on not only the quality of the material description but also a comprehensively generalized multiscale methodology which fills the theoretical gaps between the scales in an efficient yet high-fidelity manner. The conventional beam modeling methodologies which are built upon ad hoc assumptions are in lack of such reliability in need. Therefore, the focus of this dissertation is to create a reliable yet efficient method and the corresponding tool for composite beam modeling. A nonlinear beam theory is developed based on the Mechanics of Structure Genome (MSG) using the variational asymptotic method (VAM). The three-dimensional (3D) nonlinear continuum problem is rigorously reduced to a one-dimensional (1D) beam model and a two-dimensional (2D) cross-sectional analysis featuring both geometric and material nonlinearities by exploiting the small geometric parameter which is an inherent geometric characteristic of the beam. The 2D nonlinear cross-sectional analysis utilizes the 3D material models to homogenize the beam cross-sectional constitutive responses considering the nonlinear elasticity and progressive damage. The results from such a homogenization are inputs as constitutive laws into the global nonlinear 1D beam analysis. The theoretical foundation is formulated without unnecessary kinematic assumptions. Curvilinear coordinates and vector calculus are utilized to build the 3D deformation gradient tensor, of which the components are formulated in terms of cross-sectional coordinates, generalized beam strains, unknown warping functions, and the 3D spatial gradients of these warping functions. Asymptotic analysis of the extended Hamiltonian's principle suggests dropping the terms of axial gradients of the warping functions. As a result, the solid mechanics problem resolved into a 3D continuum is dimensionally reduced to a problem of solving the warping functions on a 2D cross-sectional field by minimizing the information loss. The present theory is implemented using the finite element method (FEM) in Variational Asymptotic Beam Sectional Analysis (VABS), a general-purpose cross-sectional analysis tool. An iterative method is applied to solve the finite warping field for the classical-type model in the form of the Euler-Bernoulli beam theory. The deformation gradient tensor is directly used to enable the capability of dealing with finite deformation, various strain definitions, and several types of material constitutive laws regarding the nonlinear elasticity and progressive damage. Analytical and numerical examples are given for various problems including the trapeze effect, Poynting effect, Brazier effect, extension-bending coupling effect, and free edge damage. By comparison with the predictions from 3D finite element analyses (FEA), 2D FEA based on plane stress assumptions, and experimental data, the structural and material responses are proven to be rigorously captured by the present theory and the computational cost is significantly reduced. Due to the semi-analytical feature of the code developed, the unrealistic numerical issues widely seen in the conventional FEA with strain softening material behaviors are prevented by VABS. In light of these intrinsic features, the nonlinear elastic and inelastic 3D material models can be economically calibrated by data-matching the VABS predictions directly with the experimental measurements from slender coupons. Furthermore, the global behavior of slender composite structures in meters can also be effectively characterized by VABS without unnecessary loss of important information of its local laminae in micrometers.

  2. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    A flatbed truck carrying the Orion heat shield from Exploration Flight Test-1, prepares to back into High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The heat shield was moved from the Launch Abort System Facility. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  3. Orion EFT-1 Heat Shield Move from LASF to VAB Highbay 2

    NASA Image and Video Library

    2017-04-26

    A flatbed truck carrying the Orion heat shield from Exploration Flight Test-1, backs into High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The heat shield was moved from the Launch Abort System Facility. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  4. Orion EFT-1 Heat Shield move from LASF to VAB for Ground Test Article Integration

    NASA Image and Video Library

    2017-04-26

    The heat shield for Exploration Flight Test-1 is transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations to be integrated with the Ground Test Article to be utilized for future Underway Recovery Testing. After transport from the Launch Abort System Facility (LASF) to the Vehicle Assembly Building (VAB), the heat shield is lifted off of the transport truck and placed onto foam pads (dunnage) for inspection in Highbay 2 of the VAB.

  5. KENNEDY SPACE CENTER, FLA. - Pieces of debris of Space Shuttle Columbia are offloaded from a flatbed truck in the transfer aisle of the Vehicle Assembly Building (VAB). The debris is being moved from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

    NASA Image and Video Library

    2003-09-15

    KENNEDY SPACE CENTER, FLA. - Pieces of debris of Space Shuttle Columbia are offloaded from a flatbed truck in the transfer aisle of the Vehicle Assembly Building (VAB). The debris is being moved from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

  6. STS-98 Atlantis rolls to the VAB

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. -- Space Shuttle Atlantis (right) inches its way at 1 mph atop the crawler-transporter back to the Vehicle Assembly Building from Launch Pad 39A (upper left). A panorama view from the top of the VAB shows the proximity of the pad to the Atlantic Ocean (background) plus the 3.4-mile crawlerway leading from the pad to the VAB. The water areas on both sides of the crawlerway are part of the Banana River. In the VAB workers will conduct inspections, make continuity checks and conduct X-ray analysis on the 36 solid rocket booster cables located inside each booster'''s external system tunnel. An extensive evaluation of NASA'''s SRB cable inventory revealed conductor damage in four (of about 200) cables on the shelf. Shuttle managers decided to prove the integrity of the system tunnel cables already on Atlantis before launching. The launch has been rescheduled no earlier than Feb. 6.

  7. Aerial photo shows Launch Complex 39 Area

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This aerial photo captures many of the facilities involved in Space Shuttle launches. At center is the Vehicle Assembly Building (VAB). The curved road on the near side is the newly restored crawlerway leading into the VAB high bay 2, where a mobile launcher platform/crawler-transporter currently sits. The road restoration and high bay 2 are part of KSC's Safe Haven project, enabling the storage of orbiters during severe weather. The road circles around the Orbiter Processing Facility 3 (OPF-3) at left center. OPF1 and OPF-2 are just below the curving road. The crawlerway also extends from the east side of the VAB out to the two launch pads, only one visible to the left of the VAB. In the distance is the Atlantic Ocean. To the right of the far crawlerway is the turn basin, into which ships tow the barge for offloading new external tanks from Louisiana.

  8. Further evidence for a deficit in switching attention in schizophrenia.

    PubMed

    Smith, G L; Large, M M; Kavanagh, D J; Karayanidis, F; Barrett, N A; Michie, P T; O'Sullivan, B T

    1998-08-01

    In this study, sustained, selective, divided, and switching attention, and reloading of working memory were investigated in schizophrenia by using a newly developed Visual Attention Battery (VAB). Twenty-four outpatients with schizophrenia and 24 control participants were studied using the VAB. Performance on VAB components was correlated with performance of standard tests. Patients with schizophrenia were significantly impaired on VAB tasks that required switching of attention and reloading of working memory but had normal performance on tasks involving sustained attention or attention to multiple stimulus features. Switching attention and reloading of working memory were highly correlated with Trails (B-A) score for patients. The decline in performance on the switching-attention task in patients with schizophrenia met criteria for a differential deficit in switching attention. Future research should examine the neurophysiological basis of the switching deficit and its sensitivity and specificity to schizophrenia.

  9. KSC-2011-6381

    NASA Image and Video Library

    2011-08-11

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, operators begin to move space shuttle Endeavour, its nose encased in protective plastic where its forward reaction control system (FRCS) once resided, from Orbiter Processing Facility-1 (OPF-1) to the Vehicle Assembly Building (VAB). Endeavour is switching places with shuttle Discovery which temporarily has been stored in the VAB. Both shuttles will stop briefly outside OPF-3 for a "nose-to-nose" photo opportunity. Discovery then will be rolled into OPF-1 and Endeavour into the VAB. In OPF-1, Discovery will undergo further preparations for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. Endeavour will be stored in the VAB until October when it will be moved into OPF-2 for further work to get it ready for public display at the California Science Center in Los Angeles. For more information, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jim Grossmann

  10. KSC-2011-6388

    NASA Image and Video Library

    2011-08-11

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Endeavour, its nose encased in protective plastic where its forward reaction control system (FRCS) once resided, backs out of Orbiter Processing Facility-1 (OPF-1) for its move to the Vehicle Assembly Building (VAB). Endeavour is switching places with shuttle Discovery which temporarily has been stored in the VAB. Both shuttles will stop briefly outside OPF-3 for a "nose-to-nose" photo opportunity. Discovery then will be rolled into OPF-1 and Endeavour into the VAB. In OPF-1, Discovery will undergo further preparations for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. Endeavour will be stored in the VAB until October when it will be moved into OPF-2 for further work to get it ready for public display at the California Science Center in Los Angeles. For more information, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jim Grossmann

  11. KSC-00pp0716

    NASA Image and Video Library

    2000-06-01

    KENNEDY SPACE CENTER, FLA. -- A crawler-transporter with mobile launcher platform on top tests the buried portion of the Apollo-era crawlerway leading to the Vehicle Assembly Building (VAB) high bay 2 on the southwest side. The road was restored as part of KSC’s Safe Haven project. High bay 2 provides a third stacking area. The primary goal of the Safe Haven construction project was to strengthen readiness for hurricane season by expanding the VAB’s storage capacity. The new area, in high bay 2, will allow NASA to preassemble stacks and still have room in the VAB to pull a Shuttle back from the pad if severe weather threatens. Potential rollouts of the Space Shuttle to the launch pad from high bay 2 will involve making a turn around the north side of the VAB in contrast to the straight rollouts from high bays 1 and 3, on the east side of the VAB facing the launch pads

  12. KSC00pp0716

    NASA Image and Video Library

    2000-06-01

    KENNEDY SPACE CENTER, FLA. -- A crawler-transporter with mobile launcher platform on top tests the buried portion of the Apollo-era crawlerway leading to the Vehicle Assembly Building (VAB) high bay 2 on the southwest side. The road was restored as part of KSC’s Safe Haven project. High bay 2 provides a third stacking area. The primary goal of the Safe Haven construction project was to strengthen readiness for hurricane season by expanding the VAB’s storage capacity. The new area, in high bay 2, will allow NASA to preassemble stacks and still have room in the VAB to pull a Shuttle back from the pad if severe weather threatens. Potential rollouts of the Space Shuttle to the launch pad from high bay 2 will involve making a turn around the north side of the VAB in contrast to the straight rollouts from high bays 1 and 3, on the east side of the VAB facing the launch pads

  13. The STS-93 external tank and booster stack sits at the Mobile Launcher Platform park site

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-93 stack of solid rocket boosters and external tank sits at the Mobile Launcher Platform park site waiting for lightning shield wires to be installed on the Vehicle Assembly Building (VAB) in the background. The stack is being temporarily stored outside the VAB while Space Shuttle Discovery undergoes repair to hail damage in High Bay 1. Discovery was rolled back from Pad 39B to the VAB for repairs because access to all of the damaged areas was not possible at the pad. The STS-93 stack will be moved under the wires at the VAB for protection until Discovery returns to the pad, later this week. The scheduled date for launch of mission STS-96 is no earlier than May 27. STS-93 is targeted for launch on July 22, carrying the Chandra X-ray Observatory.

  14. KENNEDY SPACE CENTER, FLA. -- Endeavour settles into place inside the Vehicle Assembly Building (VAB) where it has been moved for temporary storage. It left the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- Endeavour settles into place inside the Vehicle Assembly Building (VAB) where it has been moved for temporary storage. It left the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  15. KENNEDY SPACE CENTER, FLA. -- Endeavour rolls into the Vehicle Assembly Building (VAB) for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- Endeavour rolls into the Vehicle Assembly Building (VAB) for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  16. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines is being prepared for the move into the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platform was transported from fabricator Met-Con Inc. in Cocoa, Florida. It will be stored in the VAB, and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  17. Motor skill delays in pre-school children with leukemia one year after treatment: Hematopoietic stem cell transplantation therapy as an important risk factor.

    PubMed

    Taverna, Livia; Tremolada, Marta; Bonichini, Sabrina; Tosetto, Barbara; Basso, Giuseppe; Messina, Chiara; Pillon, Marta

    2017-01-01

    CNS-directed therapies for the treatment of leukemia can adversely affect the acquisition of new skills, such as reading/writing and math. Two years after the end of treatments, children show gross and fine motor skill delays that may persist even when patients are considered healed. The goal of the present study was to assess motor skills difficulties in pre-school children with leukemia one year after treatment. Particular attention has been paid to those patients who had undergone Hematopoietic Stem Cell Transplantation (HSCT) and to the relationship between motor delays and age bands. Participants were 60 children (median age of 5; inter quartile range: 3.07-5.76), including 31 females and 29 males, 91.7% of them were affected by acute lymphoblastic leukemia (ALL), and 8.3% by acute myeloid leukemia (AML). Five children had undergone HCST. Parents were interviewed by Vineland Adaptive Behavior Scales (VABS) on children's motor skills and filled in the Italian Temperament Questionnaire (QUIT). VABS's total scores were converted into equivalent mental age scores (EMA). A score difference of at least three months between current age and equivalent mental age was considered a developmental delay. Non-parametric analyses were run to understand if HSCT treatment and a specific age band influence children's motor skills. Significant delays were found in global motor skills (56.7%) as well as in fine and gross motor domains. Mann Whitney U tests showed that children with HSCT were reported to have lower gross motor mean ranks (U = 62; p = 0.004; Mean rank = 15.40) than peers without HSCT (Mean rank = 31.87) and lower mean rank values on motor temperament scale (U = 9; p = 0.003; HSCT Mean rank = 4.75 versus no HSCT Mean rank = 27.81). Kruskal Wallis' tests identified the high risk treatment showing that HSCT experience negatively impacted the motor skills and temperamental motor activity of pre-school children one year after the diagnosis of leukemia.

  18. A history of low birth weight alters recovery following a future head injury: a case series.

    PubMed

    Schmidt, Adam T; Li, Xiaoqi; Zhang-Rutledge, Kathy; Hanten, Gerri R; Levin, Harvey S

    2014-01-01

    Low birth weight (LBW; below 2500 grams) is a general risk factor for a variety of neurodevelopmental difficulties. However, these children may remain more vulnerable to neurologic and environmental insults occurring years later. This prospective case series reports on children who sustained a mild, moderate, or severe traumatic brain injury (TBI) in middle childhood but who had also been born with birth weights below 2500 grams. PARTICIPANTS were 14 children with mild, moderate, or severe traumatic brain injury (TBI), 5 of whom had birth weights under 2500 grams (LBW) and 9 children with normal birth weight (NBW). All participants were drawn from a larger study on the long-term cognitive and behavioral impact of pediatric TBI and were matched on age, estimated socioeconomic status (SES), and severity of TBI (with NBW children actually having a slightly worse overall injury severity). At baseline, both groups exhibited similar scores on WJ-R Letter Word Identification and Calculations, Tower of London number solved, and CVLT-C total correct. Baseline group differences were observed on the CELF-III Formulated Sentences (NBW > LBW) and on the VABS Adaptive Behavior Composite and Socialization subdomain (LBW > NBW). Over 2 years, relative to the NBW group, the LBW group evidenced declines on both WJ-R subtests, CVLT-C total correct, CELF-III Formulated Sentences, and VABS Adaptive Behavior Composite and Socialization. Although preliminary in nature due to small sample size, findings suggest a history of LBW influences the recovery trajectory following childhood TBI. Academic and adaptive functioning and verbal memory appeared particularly affected.

  19. Repainting of the VAB continues

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The worker on the lower left applies the red paint to the chevron while the worker on the right fills in the blue field to the NASA logo they are painting on the Vehicle Assembly Building (VAB). When finished, the logo, also known as the 'meatball,' will measure 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. In addition to the logo, the American flag is being repainted on the other side of the VAB. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September.

  20. KSC-2011-6387

    NASA Image and Video Library

    2011-08-11

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Endeavour, its nose encased in protective plastic where its forward reaction control system (FRCS) once resided, is towed out of Orbiter Processing Facility-1 (OPF-1) for its move to the Vehicle Assembly Building (VAB). Endeavour is switching places with shuttle Discovery which temporarily has been stored in the VAB. Both shuttles will stop briefly outside OPF-3 for a "nose-to-nose" photo opportunity. Discovery then will be rolled into OPF-1 and Endeavour into the VAB. In OPF-1, Discovery will undergo further preparations for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. Endeavour will be stored in the VAB until October when it will be moved into OPF-2 for further work to get it ready for public display at the California Science Center in Los Angeles. For more information, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jim Grossmann

  1. KENNEDY SPACE CENTER, FLA. -- Endeavour is towed in front of the Vehicle Assembly Building (VAB) where it is going for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- Endeavour is towed in front of the Vehicle Assembly Building (VAB) where it is going for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  2. STS-79 Atlantis rolls back to the VAB at sunrise

    NASA Technical Reports Server (NTRS)

    1996-01-01

    As the sun begins to rise in the early-morning sky, the Space Shuttle Atlantis slowly travels on the Crawlerway toward the Vehicle Assembly Building (VAB) after its departure from Launch Pad 39A. This marks the second rollback for Atlantis since July because of hurricane threats. Atlantis, which is targeted for liftoff later this month on the STS-79 Shuttle mission, is returning to the VAB because of the threat from Hurricane Fran. The threat of Hurricane Bertha forced the rollback of Atlantis in July. Atlantis currently is scheduled for launch on the fourth Shuttle-Mir docking mission around mid-September.

  3. Ab initio quantum chemical study of electron transfer in carboranes

    NASA Astrophysics Data System (ADS)

    Pati, Ranjit; Pineda, Andrew C.; Pandey, Ravindra; Karna, Shashi P.

    2005-05-01

    The electron transfer (ET) properties of 10- and 12-vertex carboranes are investigated by the ab initio Hartree-Fock method within the Marcus-Hush (MH) two-state model and the Koopman theorem (KT) approach. The calculated value of the ET coupling matrix element, VAB, is consistently higher in the KT approach than in the MH two-state model. For the carborane molecules functionalized by -CH 2 groups at C-vertices, VAB strongly depends on the relative orientation of the planes containing the terminal -CH 2 groups. The predicted conformation dependence of VAB offers a molecular mechanism to control ET between two active centers in molecular systems.

  4. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines, secured on a flatbed truck, has arrived at the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. It was transported from fabricator Met-Con Inc. in Cocoa, Florida. The platform will be stored in the VAB and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1 (EM-1). During EM-1, an uncrewed Orion spacecraft will launch on the SLS to a stable orbit beyond the Moon and return to Earth for a splashdown in the Pacific Ocean.

  5. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines has been offloaded from a flatbed truck and is being prepared for the move into the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platform was transported from fabricator Met-Con Inc. in Cocoa, Florida. It will be stored in the VAB, and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  6. 32 CFR 728.52 - Veterans Administration beneficiaries (VAB).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Veterans Administration beneficiaries (VAB). 728.52 Section 728.52 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Beneficiaries of Other...

  7. 32 CFR 728.52 - Veterans Administration beneficiaries (VAB).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Veterans Administration beneficiaries (VAB). 728.52 Section 728.52 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Beneficiaries of Other...

  8. 32 CFR 728.52 - Veterans Administration beneficiaries (VAB).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Veterans Administration beneficiaries (VAB). 728.52 Section 728.52 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Beneficiaries of Other...

  9. Advanced Low NO Sub X Combustors for Supersonic High-Altitude Aircraft Gas Turbines

    NASA Technical Reports Server (NTRS)

    Roberts, P. B.; White, D. J.; Shekleton, J. R.

    1975-01-01

    A test rig program was conducted with the objective of evaluating and minimizing the exhaust emissions, in particular NO sub x, of three advanced aircraft combustor concepts at a simulated, high altitude cruise condition. The three combustor designs, all members of the lean reaction, premixed family, are the Jet Induced Circulation (JIC) combustor, the Vortex Air Blast (VAB) combustor, and a catalytic combustor. They were rig tested in the form of reverse flow can combustors in the 0.127 m. (5.0 in.) size range. Various configuration modifications were applied to each of the initial JIC and VAB combustor model designs in an effort to reduce the emissions levels. The VAB combustor demonstrated a NO sub x level of 1.1 gm NO2/kg fuel with essentially 100% combustion efficiency at the simulated cruise combustor condition of 50.7 N/sq cm (5 atm), 833 K (1500 R) inlet pressure and temperature respectively and 1778 K (3200 R) outlet temperature on Jet-A1 fuel. Early tests on the catalytic combustor were unsuccessful due to a catalyst deposition problem and were discontinued in favor of the JIC and VAB tests. In addition emissions data were obtained on the JIC and VAB combustors at low combustor inlet pressure and temperatures that indicate the potential performance at engine off-design conditions.

  10. Longitudinal trajectories of intellectual and adaptive functioning in adolescents and adults with Williams syndrome.

    PubMed

    Fisher, M H; Lense, M D; Dykens, E M

    2016-10-01

    Williams syndrome (WS) is associated with a distinct cognitive-behavioural phenotype including mild to moderate intellectual disability, visual-spatial deficits, hypersociability, inattention and anxiety. Researchers typically characterise samples of individuals with WS by their intellectual functioning and adaptive behaviour. Because of the low prevalence of the syndrome, researchers often include participants with WS across a broad age range throughout childhood and adulthood and assume participants demonstrate consistent cognitive development across ages. Indeed, IQ scores are generally stable for children and adolescents with WS, although there are significant individual differences. It is less clear whether this pattern of stable intellectual ability persists into adulthood. Furthermore, while adaptive behaviour is an important indicator of an individual's ability to apply their conceptual skills to everyday functioning, conflicting findings on the trajectories of adaptive behaviour in adolescents and adults with WS have been reported. The current study examined longitudinal profiles of cognitive and adaptive functioning in adolescents and adults with WS. To examine cognitive functioning, participants included 52 individuals with WS (51.9% men) who were assessed with the Kaufman Brief Intelligence Test, 2nd edition (KBIT-2) between two and seven times. At their first assessment, participants had a mean age of 25.4 years (SD = 8.4), ranging in age from 14.2 to 48.9 years. To assess adaptive behaviour, participants included a subset of 28 individuals with WS whose parents completed the Vineland Adaptive Behavior Scale, 2nd edition (VABS-II) between two and five times. At their initial administration, participants ranged from 17.1-40.2 years of age, with a mean age of 26.5 years (SD = 7.3). A series of multilevel models were used to examine changes in KBIT-2 Composite IQ, Verbal IQ and Nonverbal IQ standard scores over time, as well as the Adaptive Behavior Composite, and the Communication, Daily Living Skills and Socialization subdomains of the VABS-II. Consistent with the WS cognitive profile, IQ scores were significantly lower than the general population IQ score of 100, and there was significant variability in individual IQ scores and slopes. KBIT-2 IQ scores were generally stable across adolescents and adults with WS. Adaptive behaviour scores were significantly lower than the population mean score of 100, and there was significant variability in individuals' adaptive behaviour scores but not trajectories. However, in contrast to the findings with the KBIT-2, VABS-II scores were observed to significantly decrease over time. Findings suggest that while intellectual functioning remains stable, adaptive functioning does not remain stable across adolescence and adulthood in individuals with WS. Implications for the relation between cognitive and adaptive functioning across development are discussed, with a focus on how this relates to specific aspects of the WS phenotype. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  11. KSC-06pd0820

    NASA Image and Video Library

    2006-05-12

    KENNEDY SPACE CENTER, FLA. - The orbiter Discovery, on top of an orbiter transporter, heads toward NASA's Vehicle Assembly Building (VAB) after leaving the Orbiter Processing Facility. The rollover to the VAB marks the start of the journey to the launch pad and, ultimately, launch. Once inside the VAB, Discovery will be raised to vertical and lifted up and over into high bay 3 for stacking with its redesigned external tank and twin solid rocket boosters. The rollout of Space Shuttle Discovery to Launch Pad 39B is expected in approximately a week. Launch of Discovery on mission STS-121 is scheduled to take place in a window extending July 1 to July 19. Photo credit: NASA/Jim Grossmann

  12. KSC-06pd0821

    NASA Image and Video Library

    2006-05-12

    KENNEDY SPACE CENTER, FLA. - The orbiter Discovery, on top of an orbiter transporter, rolls into NASA's Vehicle Assembly Building (VAB) after leaving the Orbiter Processing Facility. The rollover to the VAB marks the start of the journey to the launch pad and, ultimately, launch. Once inside the VAB, Discovery will be raised to vertical and lifted up and over into high bay 3 for stacking with its redesigned external tank and twin solid rocket boosters. The rollout of Space Shuttle Discovery to Launch Pad 39B is expected in approximately a week. Launch of Discovery on mission STS-121 is scheduled to take place in a window extending July 1 to July 19. Photo credit: NASA/Jim Grossmann

  13. Booster Engine Service Platforms Delivered to VAB

    NASA Image and Video Library

    2018-04-17

    A new service platform for NASA's Space Launch System booster engines, secured on a flatbed truck, is on its way to the Vehicle Assembly Building (VAB), in view in the distance, at the agency's Kennedy Space Center in Florida. It was transported from fabricator Met-Con Inc. in Cocoa, Florida. The platform will be delivered to the VAB, where it will be stored and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1 (EM-1). During EM-1, an uncrewed Orion spacecraft will launch on the SLS to a stable orbit beyond the Moon and return to Earth for a splashdown in the Pacific Ocean.

  14. Platform C South Arrival

    NASA Image and Video Library

    2016-08-05

    A heavy load transport truck from Tillett Heavy Hauling in Titusville, Florida, arrives at the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida, carrying the second section of the first half of the C-level work platforms, C South, for the agency’s Space Launch System (SLS) rocket. The platform will be offloaded in the VAB staging area in the west parking lot. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft and provide access for testing and processing.

  15. Platform C South Arrival

    NASA Image and Video Library

    2016-08-04

    A heavy load transport truck from Tillett Heavy Hauling in Titusville, Florida, arrives at the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida, carrying a section of the first half of the C-level work platforms, C south, for the agency’s Space Launch System (SLS) rocket. The platform will be delivered to the VAB staging area in the west parking lot. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft and provide access for testing and processing.

  16. Apollo spacecraft Command/Service Module and Lunar Module 3 arrive at VAB

    NASA Image and Video Library

    1968-12-03

    Apollo Spacecraft 104 Command/Service Module and Lunar Module 3 arrive at the Vehicle Assembly Building (VAB) for mating atop the Saturn 504 launch vehicle. The Saturn 504 stack is out of view. The Saturn V first (S-IC) stage in left background is scheduled for a later flight.

  17. Georgia Tech Vertical Lift Research Center of Excellence

    DTIC Science & Technology

    2017-12-14

    Technical Project Summaries Task 1.1 (GT-1): Next Generation VABS for More Realistic Modeling of Composite Blades ...Methodology for the Prediction of Rotor Blade Ice Formation and Shedding ..................................................................... 20...software disclosures and technology transfer efforts. Task 1.1 (GT-1): Next Generation VABS for More Realistic Modeling of Composite Blades PIs

  18. APOLLO 4 SATURN V LAUNCH VEHICLE MATING INSIDE VEHICLE ASSEMBLY BUILDING [VAB

    NASA Technical Reports Server (NTRS)

    1967-01-01

    The S II stage of the Apollo/Saturn 501 launch vehicle is being mated to the first stage at the Vehicle Assembly Building [VAB] in preparation for the National Aeronautics and Space Administration's first Saturn V mission. The mission will be unmanned and is scheduled early this year.

  19. Wide range operation of advanced low NOx combustors for supersonic high-altitude aircraft gas turbines

    NASA Technical Reports Server (NTRS)

    Roberts, P. B.; Fiorito, R. J.

    1977-01-01

    An initial rig program tested the Jet Induced Circulation (JIC) and Vortex Air Blast (VAB) systems in small can combustor configurations for NOx emissions at a simulated high altitude, supersonic cruise condition. The VAB combustor demonstrated the capability of meeting the NOx goal of 1.0 g NO2/kg fuel at the cruise condition. In addition, the program served to demonstrate the limited low-emissions range available from the lean, premixed combustor. A follow-on effort was concerned with the problem of operating these lean, premixed combustors with acceptable emissions at simulated engine idle conditions. Various techniques have been demonstrated that allow satisfactory operation on both the JIC and VAB combustors at idle with CO emissions below 20 g/kg fuel. The VAB combustor was limited by flashback/autoignition phenomena at the cruise conditions to a pressure of 8 atmospheres. The JIC combustor was operated up to the full design cruise pressure of 14 atmospheres without encountering an autoignition limitation although the NOx levels, in the 2-3 g NO2/kg fuel range, exceeded the program goal.

  20. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis approaches the Vehicle Assembly Building (VAB). It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis approaches the Vehicle Assembly Building (VAB). It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  1. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  2. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis nears the Vehicle Assembly Building (VAB). It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis nears the Vehicle Assembly Building (VAB). It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  3. KENNEDY SPACE CENTER, FLA. -- After Endeavour’s rollout from inside the Orbiter Processing Facility, the transporter (foreground) prepares to tow it to the Vehicle Assembly Building for temporary transfer. A protective cover surrounds the nose of Endeavour. The move to the VAB allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- After Endeavour’s rollout from inside the Orbiter Processing Facility, the transporter (foreground) prepares to tow it to the Vehicle Assembly Building for temporary transfer. A protective cover surrounds the nose of Endeavour. The move to the VAB allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  4. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis awaits transport from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis awaits transport from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  5. [Diagnosis of flat epithelial atypia (FEA) after stereotactic vacuum-assisted biopsy (VAB) of the breast: What is the best management: systematic surgery for all or follow-up?].

    PubMed

    David, N; Labbe-Devilliers, C; Moreau, D; Loussouarn, D; Campion, L

    2006-11-01

    FEA lesions group two histological types: columnar cell hyperplasia with atypia (CCHA) and columnar cell change with atypia (CCA). The increasing use of VAB has resulted in increased detection of isolated FEA lesions. The aim of this study was to define the best management possible for these patients: which cases may not need excision? From our database of 780 VABs carried out from 2000 to 2004, 59 patients with FEA were diagnosed. Cases in which no surgery was performed or all features were not available were excluded, thus excluding 19 cases. Forty patients with FEA were included. We reviewed clinical and mammographic characteristics, histological biopsy, and the corresponding surgically excised tissue features. VAB yielded 25 cases of CCHA and 15 cases of CCA. Surgery revealed seven ductal carcinoma cases (four invasive, three in situ); nine benign lesions, and 24 with atypia (19 FEA and six atypical ductal hyperplasia). We found two features related to the risk of cancer: the presence and the size of hyperplasia. All carcinomas were found within the CCHA lesions. No cancer was yielded when size was less than 10 mm within CCA lesions and lesions that were totally removed. We recommend surgical excision when CCHA greater than 10 mm is found on the VAB or it is incompletely removed. CCA lesions or CCHA less than 10 mm or totally removed may obviate systematic surgery.

  6. Conserved gene regulatory module specifies lateral neural borders across bilaterians

    PubMed Central

    Li, Yongbin; Zhao, Di; Horie, Takeo; Chen, Geng; Bao, Hongcun; Chen, Siyu; Liu, Weihong; Horie, Ryoko; Liang, Tao; Dong, Biyu; Feng, Qianqian; Tao, Qinghua

    2017-01-01

    The lateral neural plate border (NPB), the neural part of the vertebrate neural border, is composed of central nervous system (CNS) progenitors and peripheral nervous system (PNS) progenitors. In invertebrates, PNS progenitors are also juxtaposed to the lateral boundary of the CNS. Whether there are conserved molecular mechanisms determining vertebrate and invertebrate lateral neural borders remains unclear. Using single-cell-resolution gene-expression profiling and genetic analysis, we present evidence that orthologs of the NPB specification module specify the invertebrate lateral neural border, which is composed of CNS and PNS progenitors. First, like in vertebrates, the conserved neuroectoderm lateral border specifier Msx/vab-15 specifies lateral neuroblasts in Caenorhabditis elegans. Second, orthologs of the vertebrate NPB specification module (Msx/vab-15, Pax3/7/pax-3, and Zic/ref-2) are significantly enriched in worm lateral neuroblasts. In addition, like in other bilaterians, the expression domain of Msx/vab-15 is more lateral than those of Pax3/7/pax-3 and Zic/ref-2 in C. elegans. Third, we show that Msx/vab-15 regulates the development of mechanosensory neurons derived from lateral neural progenitors in multiple invertebrate species, including C. elegans, Drosophila melanogaster, and Ciona intestinalis. We also identify a novel lateral neural border specifier, ZNF703/tlp-1, which functions synergistically with Msx/vab-15 in both C. elegans and Xenopus laevis. These data suggest a common origin of the molecular mechanism specifying lateral neural borders across bilaterians. PMID:28716930

  7. Conserved gene regulatory module specifies lateral neural borders across bilaterians.

    PubMed

    Li, Yongbin; Zhao, Di; Horie, Takeo; Chen, Geng; Bao, Hongcun; Chen, Siyu; Liu, Weihong; Horie, Ryoko; Liang, Tao; Dong, Biyu; Feng, Qianqian; Tao, Qinghua; Liu, Xiao

    2017-08-01

    The lateral neural plate border (NPB), the neural part of the vertebrate neural border, is composed of central nervous system (CNS) progenitors and peripheral nervous system (PNS) progenitors. In invertebrates, PNS progenitors are also juxtaposed to the lateral boundary of the CNS. Whether there are conserved molecular mechanisms determining vertebrate and invertebrate lateral neural borders remains unclear. Using single-cell-resolution gene-expression profiling and genetic analysis, we present evidence that orthologs of the NPB specification module specify the invertebrate lateral neural border, which is composed of CNS and PNS progenitors. First, like in vertebrates, the conserved neuroectoderm lateral border specifier Msx/vab-15 specifies lateral neuroblasts in Caenorhabditis elegans Second, orthologs of the vertebrate NPB specification module ( Msx/vab-15 , Pax3/7/pax-3 , and Zic/ref-2 ) are significantly enriched in worm lateral neuroblasts. In addition, like in other bilaterians, the expression domain of Msx/vab-15 is more lateral than those of Pax3/7/pax-3 and Zic/ref- 2 in C. elegans Third, we show that Msx/vab-15 regulates the development of mechanosensory neurons derived from lateral neural progenitors in multiple invertebrate species, including C. elegans , Drosophila melanogaster , and Ciona intestinalis We also identify a novel lateral neural border specifier, ZNF703/tlp-1 , which functions synergistically with Msx/vab- 15 in both C. elegans and Xenopus laevis These data suggest a common origin of the molecular mechanism specifying lateral neural borders across bilaterians.

  8. Analysis of a Hypergolic Propellant Explosion During Processing of Launch Vehicles in the VAB

    NASA Technical Reports Server (NTRS)

    Chrostowski, Jon D.; Gan Wenshui; Campbell, Michael D.

    2010-01-01

    NASA is developing launch vehicles to support missions to Low Earth Orbit (LEO), the moon and deep space. Whether manned or unmanned, the vehicle components will likely be integrated in the Vehicle Assembly Building (VAB) at Kennedy Space Center (KSC) and typically include a fueled spacecraft (SC) that sits on top of one or more stages. The processing of a fueled SC involves hazardous operations when it is brought into the VAB Transfer Aisle and lifted a significant height for mating with lower stages. Accidents resulting from these hazardous operations could impact unrelated personnel working in buildings adjacent to the VAB. Safe separation distances based on the DOD Explosives Standards Quantity-Distance (Q-D) approach result in large IBD arcs. This paper presents site-specific air blast and fragmentation hazard analyses for comparison with the Q-D arcs as well as consequence and risk analyses to provide added information for the decision maker. A new physics-based fragmentation model is presented that includes: a) the development of a primary fragment list (which defines the fragment characteristics) associated with a hypergolic propellant explosion, b) a description of a 3D fragment bounce model, c) the results of probabilistic Monte-Carlo simulations (that include uncertainties in the fragment characteristics) to determine: i) the hazardous fragment density distance, ii) the expected number of wall/roof impacts and penetrations to over 40 buildings adjacent to the VAB, and iii) the risk to building occupants.

  9. Intensive intervention for children and adolescents with autism in a community setting in Italy: a single-group longitudinal study

    PubMed Central

    2010-01-01

    Background Previous studies have shown favourable results with intensive behavioural treatment for children with autism: evidence has emerged that treatment can be successfully implemented in a community setting and in adolescent participants. The aim of this study was to describe the 2-year adaptive functioning outcome of children and adolescents with autism treated intensively within the context of special autism centres, as well as to evaluate family satisfaction with the activity of the centres. Methods Sixty participants with autism (20 females and 40 males, aged between 4 and 18 years) attending the semi-residential rehabilitation centres for autism located in the Abruzzo region (Central Italy) were followed up and their adaptive functioning was evaluated both at baseline and after one and two years using the Vineland Adaptive Behaviour Scales (VABS). Parents' satisfaction with the service was evaluated using the Orbetello Satisfaction Scale for Children and Adolescent Mental Health. Results The increase in VABS scores was significant on several domains in the different gender and age categories. It is worth noting that male children had improved a great deal (roughly, an effect size >0.20) in the domains of communication, daily living and motor skills (effect sizes 0.34, 0.45 and 0.27 respectively) whereas in male adolescents, a notable increase in VABS scores was recorded in the domain of socialization only (effect size 0.23). On the other hand, adaptive behaviour in female children increased in the domains of socialization and motor skills (effect sizes 0.27 and 0.42 respectively) whereas in female adolescents, good results were achieved in the domains of daily living, socialization and motor skills (effect sizes 0.22, 0.26 and 0.20 respectively). The level of satisfaction of users of the service over time was found to be substantial, even when they had recently started the program. Conclusions Our results support the implementation of special autism treatment community centres, based on a parent co-directed rehabilitative, intensive and early intervention. Further experimental research designed to document the effectiveness of services provided to children and adolescents with autism in the community is recommended. PMID:20809976

  10. A System for Measuring the Sway of the Vehicle Assembly Building

    NASA Technical Reports Server (NTRS)

    Youngquist, Robert; Starr, Stanley; Lane, John; Simmons, Stephen; Ihlefeld, Curtis

    2013-01-01

    A system was developed to measure the sway of the Vehicle Assembly Building (VAB) at Kennedy Space Center. This system was installed in the VAB and gathered more than one total year of data. The building movement was correlated with measurements provided by three wind towers in order to determine the maximum deflection of the building during high-wind events. The VAB owners were in the process of obtaining new platforms for use in assembling very tall rockets when analysis of the VAB showed that a high wind could move the building sufficiently that an upper platform might impact a rocket. The problem arises because safety requires a relatively small gap between the platform and the rocket, while a large enough gap is needed to ensure that stacking tolerances prevent contact between the rocket and the platform. This only leaves an inch or two (approximately 2 to 5 cm) of total clearance, so when the analysis showed that more than a couple of inches of motion could occur in a high wind, there was a potential for damaging the rocket. The KSC Applied Physics Laboratory was asked to install a system in the VAB that could measure the motion of the building in high winds to determine the actual building sway. The motion of the VAB roof under wind load was measured optically, and under analysis, it was determined that a relatively large-aperture optical system would be required to reduce diffraction effects to less than a small fraction of an inch (approximately mm) at a distance of 500 ft (˜150 m). A 10-in. (approximately 250 mm) telescope was placed on the floor of the building, looking at the ceiling. On the ceiling, a flat plate with three white LEDs was mounted in an "L" shape, such that the telescope was essentially looking at three stars. Software was written to track the motion of these three points using an image processing system. This provided a better than 1/10-in. (approximately 2.5-mm) 2D measurement faster than once a second. Data was downloaded once a month for comparison with the wind tower data. The system was fully operational and provided enough data to show that the VAB will only move 1 in. (approximately 2.5 cm) at the ceiling under 70-knot winds. Adjustable platforms are not required.

  11. Length-dependence of intramolecular electron transfer in σ-bonded rigid molecular rods: an ab initio molecular orbital study

    NASA Astrophysics Data System (ADS)

    Pati, Ranjit; Karna, Shashi P.

    2002-01-01

    The dependence of electron transfer (ET) coupling element, VAB, on the length of rigid-rod-like systems consisting of bicyclo[1.1.1]pentane (BCP), cubane (CUB), and bicyclo[2.2.2]octane (BCO) monomers, has been investigated with the use of ab initio Hartree-Fock (HF) method employing Marcus-Hush two-state (TS) model. The value of VAB decreases exponentially with increase in the number of the cage units of the σ-bonded molecules. The calculated decay constant, β, shows good agreement with previously reported data. For molecular length⩾15 Å, the value of VAB becomes negligibly small, suggesting complete suppression of the through bond direct tunneling contribution to ET process.

  12. STS-35 Columbia, OV-102, rolls back to KSC VAB after hydrogen leak discovered

    NASA Image and Video Library

    1990-06-12

    S90-42289 ( 3 July 1990) --- Kennedy Space Center (KSC) workers watch as Columbia, Orbiter Vehicle (OV) 102, along with its external tank (ET) and two solid rocket boosters (SRBs) atop the giant crawler transporter, rolls back to KSC's Vehicle Assembly Building (VAB). The rollback was caused by a hydrogen leak that stopped the STS-35 countdown during ET fueling, 05-29-90. Once in the VAB, OV-102 and its stack will be demated, and OV-102, with its Astronomy Laboratory 1 (ASTRO-1) payload aboard, will be moved to the Orbiter Processing Facility (OPF) to await return to KSC Launch Complex (LC) Pad 39A. View provided by KSC with alternate number KSC-90PC-901.

  13. Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons

    PubMed Central

    Yan, Dong

    2016-01-01

    Gap junctions are present in both vertebrates and invertebrates from nematodes to mammals. Although the importance of gap junctions has been documented in many biological processes, the molecular mechanisms underlying gap junction dynamics remain unclear. Here, using the C. elegans PLM neurons as a model, we show that UNC-44/ankyrin acts upstream of UNC-33/CRMP in regulation of a potential kinesin VAB-8 to control gap junction dynamics, and loss-of-function in the UNC-44/UNC-33/VAB-8 pathway suppresses the turnover of gap junction channels. Therefore, we first show a signal pathway including ankyrin, CRMP, and kinesin in regulating gap junctions. PMID:27015090

  14. Platform C South Arrival

    NASA Image and Video Library

    2016-08-04

    A heavy load transport truck from Tillett Heavy Hauling in Titusville, Florida, arrives at the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida, carrying a section of the first half of the C-level work platforms, C South, for the agency’s Space Launch System (SLS) rocket. The platform is being lifted and transferred onto support stands in the VAB staging area in the west parking lot. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft and provide access for testing and processing.

  15. VAB Temperature and Humidity Study

    NASA Technical Reports Server (NTRS)

    Lane, John E.; Youngquist, Robert C.; Muktarian, Edward; Nurge, Mark A.

    2014-01-01

    In 2012, 17 data loggers were placed in the VAB to measure temperature and humidity at 10-minute intervals over a one-year period. In 2013, the data loggers were replaced with an upgraded model and slight adjustments to their locations were made to reduce direct solar heating effects. The data acquired by the data loggers was compared to temperature data provided by three wind towers located around the building. It was found that the VAB acts as a large thermal filter, delaying and reducing the thermal oscillations occurring outside of the building. This filtering is typically more pronounced at higher locations in the building, probably because these locations have less thermal connection with the outside. We surmise that the lower elevations respond more to outside temperature variations because of air flow through the doors. Temperatures inside the VAB rarely exceed outdoor temperatures, only doing so when measurements are made directly on a surface with connection to the outside (such as a door or wall) or when solar radiation falls directly on the sensor. A thermal model is presented to yield approximate filter response times for various locations in the building. Appendix A contains historical thermal and humidity data from 1994 to 2009.

  16. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis moves into high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis moves into high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  17. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis awaits a tow from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis awaits a tow from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  18. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is turned into position outside the Orbiter Processing Facility (OPF) for its tow to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is turned into position outside the Orbiter Processing Facility (OPF) for its tow to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  19. KENNEDY SPACE CENTER, FLA. - Workers back the Space Shuttle orbiter Atlantis out of the Orbiter Processing Facility (OPF) for its move to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - Workers back the Space Shuttle orbiter Atlantis out of the Orbiter Processing Facility (OPF) for its move to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  20. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is moved into high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is moved into high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  1. KENNEDY SPACE CENTER, FLA. - Workers prepare to tow the Space Shuttle orbiter Atlantis from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - Workers prepare to tow the Space Shuttle orbiter Atlantis from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  2. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is moments away from a tow from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is moments away from a tow from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  3. KENNEDY SPACE CENTER, FLA. - Workers monitor the Space Shuttle orbiter Atlantis as it is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - Workers monitor the Space Shuttle orbiter Atlantis as it is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  4. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis approaches the Vehicle Assembly Building (VAB) high bay 4. It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis approaches the Vehicle Assembly Building (VAB) high bay 4. It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  5. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis approaches high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis approaches high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  6. KENNEDY SPACE CENTER, FLA. - Workers walk with Space Shuttle orbiter Atlantis from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB) high bay 4. The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - Workers walk with Space Shuttle orbiter Atlantis from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB) high bay 4. The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  7. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis backs out of the Orbiter Processing Facility (OPF) for its move to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis backs out of the Orbiter Processing Facility (OPF) for its move to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  8. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis arrives in high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis arrives in high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  9. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is almost in position in high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is almost in position in high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  10. KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is reflected in a rain puddle as it is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-05

    KENNEDY SPACE CENTER, FLA. - The Space Shuttle orbiter Atlantis is reflected in a rain puddle as it is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  11. Cerebellar lesions in tuberous sclerosis complex: neurobehavioral and neuroimaging correlates.

    PubMed

    Eluvathingal, Thomas J; Behen, Michael E; Chugani, Harry T; Janisse, James; Bernardi, Bruno; Chakraborty, Pulak; Juhasz, Csaba; Muzik, Otto; Chugani, Diane C

    2006-10-01

    We assessed the structural and functional imaging features of cerebellar lesions and their neurobehavioral correlates in a large cohort of patients with tuberous sclerosis complex. A consecutive series of 78 patients with tuberous sclerosis complex underwent magnetic resonance imaging (MRI) and positron emission tomography (PET) studies with [(18)F]fluorodeoxyglucose (FDG) and alpha-[(11)C]methyl-l-tryptophan (AMT) as part of their evaluation for epilepsy surgery. Neurobehavioral assessment included the Gilliam Autism Rating Scales (GARS) and the Vineland Adaptive Behavior Scales (VABS). Twenty-one patients (27%) had cerebellar lesions (10 boys; mean age 9 +/- 8 years; 9 had right-sided, 10 had left-sided, and 2 had bilateral cerebellar lesions). The lesions showed decreased glucose metabolism (0.79 +/- 0.10) and increased (1.04 +/- 0.10) AMT uptake compared with the normal (nonlesional) cerebellar cortex. Comparisons between patients with (n = 20) and without (n = 57) a cerebellar lesion on neurobehavioral functioning, controlling for the number and location of cortical tubers, revealed that the cerebellar lesion group had higher overall autistic symptomatology. Within-group analyses of the cerebellar lesion group revealed that children with right-sided cerebellar lesions had higher social isolation and communicative and developmental disturbance compared with children with left-sided cerebellar lesions. The side of the cerebellar lesion was not related to adaptive behavior functioning. These findings provide additional empiric support for a role of the cerebellum in autistic symptomatology. Further investigation of the potential role of the right cerebellum in autism, particularly with regard to the dentatothalamofrontal circuit, is warranted.

  12. KSC-04pd0664

    NASA Image and Video Library

    2004-03-26

    CAPE CANAVERAL, Fla. -- This aerial photo shows the expanse of the Launch Complex 39 Area, bordered on the east by the Atlantic Ocean and cloud-filled sky. At center right, towering above the surrounding sites, is the Vehicle Assembly Building. To the left, or north, is the Orbiter Processing Facility’s Bay 3. On the western side are OPF Bays 1 and 2. In the lower right corner is the Operations Support Building. The two-lane crawlerway stretches from the VAB toward the coast, site of Launch Pad 39A, closest, and Launch Pad 39B, far left. Between the VAB and the ocean sprawl the Banana Creek and the Banana River. The turn basin, at right, allows delivery of external tanks that are offloaded close to and transported to the VAB. Photo credit: NASA

  13. Repainting of the VAB continues

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The Vehicle Assembly Building (VAB) gets a facelift with the repainting of the American flag and replacing of the bicentennial emblem with the NASA logo. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid- September. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the 'meatball,' will measure 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls.

  14. The course of cognitive-behavioral development in children with the FMR1 mutation, Williams-Beuren syndrome, and neurofibromatosis type 1: The effect of gender.

    PubMed

    Fisch, Gene S; Carpenter, Nancy; Howard-Peebles, Patricia N; Holden, Jeanette J A; Tarleton, Jack; Simensen, Richard

    2010-06-01

    The course of cognitive-behavioral development in children with intellectual disabilities produced by genetic disorders has only recently begun to be examined systematically. Unfortunately, these studies are few in number. Previously, we examined cognitive-behavioral development in children with the fragile X (FMR1) mutation and found longitudinal decreases in both IQ and adaptive behavior (DQ) scores in most males and females with the full mutation. In this study, we examine longitudinal changes in IQ and DQ in children with neurofibromatosis type 1 (NF1) and Williams-Beuren Syndrome (WBS) by examining differences in composite IQ and DQ scores between the first test (T1) and retest (T2), and compare their developmental trajectory to children with the FMR1 mutation. Sixty-five children with the FMR1 mutation, or NF1, or WBS, ages 4-16 years, were retested two years after initial testing with the Stanford-Binet 4th Edition (SBFE) and the Vineland Adaptive Behavior Scale (VABS). In addition to significant longitudinal declines in IQ and DQ noted previously in children with the FMR1 mutation, we found significant decreases in IQ in males compared to females in the remainder of our sample. We also observed statistically significant decreases in DQ scores among children the FMR1 mutation, as noted previously, but not among children with NF1 or WBS. Moreover, significant declines were found only among males with the FMR1 mutation. Unlike declines in IQ scores, decreases in DQ were not significantly different between males and females. (c) 2010 Wiley-Liss, Inc.

  15. Papilloma diagnosed at MRI-guided vacuum-assisted breast biopsy: is surgical excision still warranted?

    PubMed

    Brennan, Sandra B; Corben, Adriana; Liberman, Laura; Dershaw, D David; Brogi, Edi; Van Zee, Kimberly J; Morris, Elizabeth

    2012-10-01

    The objective of our study was to determine the frequency of cancer at surgery in breast lesions yielding papilloma at MRI-guided 9-gauge vacuum-assisted biopsy (VAB) and to determine whether any features are associated with cancer upgrade. For this study, 1487 MRI-guided vacuum-assisted biopsies performed from January 2004 to March 2011 were reviewed. Lesions yielding papilloma were identified and classified as papilloma with or without atypia. Surgical findings were reviewed to determine the cancer rate. Statistical analysis was performed and 95% CIs were calculated. Papilloma was identified in 75 of the 1487 MRI-guided vacuum-assisted biopsies (5%). These 75 papillomas occurred in 73 women with a median age of 49 years (age range, 27-70 years). Of the 75 papillomas, 25 (33%) had atypia and 50 (67%) did not on core needle biopsy. Subsequent surgery of 67 of the 75 papillomas (89%) yielded ductal carcinoma in situ (DCIS) in four (6%; 95% CI, 2-15%). Surgery yielded DCIS in two of 23 papillomas with atypia (9%; 95% CI, 1-28%) at MRI-guided VAB and in two of 44 papillomas without atypia (5%; 95% CI, 0.4-16%) at MRI-guided VAB; these cancer rates did not differ significantly (p=0.6). Postmenopausal status (p=0.04) and histologic size of less than 0.2 cm (p=0.04) had a significant association with the cancer upgrade rate. Papilloma with or without atypia was found in 5% of patients who underwent MRI-guided VAB during the study period. Surgery revealed cancer in 6%. DCIS was found at surgery in 9% of lesions yielding papilloma with atypia versus 5% of lesions yielding papilloma without atypia. For lesions yielding papilloma with or without atypia at MRI-guided VAB, surgical excision is warranted.

  16. Aerial photo shows Launch Complex 39 Area

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This aerial photo captures many of the facilities involved in Space Shuttle launches. At center is the Vehicle Assembly Building (VAB), with the Launch Control Center at its right. The curved road on the left in the photo is the newly restored crawlerway leading into the VAB high bay 2, where a mobile launcher platform/crawler-transporter sits. The road restoration and high bay 2 are part of KSC's Safe Haven project, enabling the storage of orbiters during severe weather. The crawlerway also extends from the east side out to the two launch pads, one visible close to the road on the left and one to the left of the VAB. In the distance is the Atlantic Ocean. To the right of the crawlerway is the turn basin, into which ships tow the barge for offloading new external tanks from Louisiana.

  17. Repainting of the VAB nearly finished

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This aerial view shows the Vehicle Assembly Building (VAB) getting a facelift with the repainting of the American flag and replacing of the Bicentennial emblem with the NASA logo. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the 'meatball,' measures 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls.

  18. Repainting of the VAB nearly finished

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This aerial view shows the Vehicle Assembly Building (VAB) getting a facelift with the repainting of the American flag and replacing of the bicentennial emblem with the NASA logo. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the 'meatball,' measures 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls.

  19. KSC-98pc988

    NASA Image and Video Library

    1998-08-28

    KENNEDY SPACE CENTER, FLA. -- The American flag is being repainted on the side of the Vehicle Assembly Building (VAB). The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. In addition to the flag, the NASA logo, also known as the "meatball," is being painted on the VAB. When finished, the logo will measure 110 feet by 132 feet, or about 12,300 square feet. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. The painting honors NASA’s 40th anniversary on Oct. 1 and is expected to be complete in mid-September

  20. KSC-03pd2614

    NASA Image and Video Library

    2003-09-15

    KENNEDY SPACE CENTER, FLA. - A flatbed truck carrying pieces of debris of Space Shuttle Columbia arrives outside the Vehicle Assembly Building (VAB). The debris is being transferred from the Columbia Debris Hangar to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

  1. KSC-03pd2225

    NASA Image and Video Library

    2003-07-23

    CAPE CANAVERAL, Fla. -- This view shows much of the Launch Complex 39 Area looking north. At center is the 525-foot-tall Vehicle Assembly Building. Other buildings surrounding it are counter clockwise from left the Orbiter Processing Facility, Multi-Function Facility, Operations Support Building and Launch Control Center, next to the VAB. The crawlerway leads from the VAB toward the launch pads. In the background are the waters of the Banana Creek. Photo credit: NASA

  2. KSC-00padig095

    NASA Image and Video Library

    2000-11-21

    KENNEDY SPACE CENTER, FLA. -- A newly arrived external tank is transported from the turn basin to the Vehicle Assembly Building (VAB), seen behind the tank. External tanks are built by the NASA Michoud Assembly Facility in New Orleans and transported by barge to Cape Canaveral and then up the Banana River to the turn basin in the Launch Complex 39 Area. In the VAB, the tank will await stacking for a future Shuttle mission

  3. 03pd2225

    NASA Image and Video Library

    2003-07-23

    KENNEDY SPACE CENTER, FLA. – This view shows much of the Launch Complex 39 Area looking north. At center is the 525-foot-tall Vehicle Assembly Building. Other buildings surrounding it are (counter clockwise from left) the Orbiter Processing Facility, Multi-Function Facility, Operations Support Building and Launch Control Center (next to VAB). The crawlerway leads from the VAB toward the launch pads. In the background are the waters of the Banana Creek.

  4. KSC00padig096

    NASA Image and Video Library

    2000-11-21

    KENNEDY SPACE CENTER, FLA. -- A newly arrived external tank heads from the turn basin toward the Vehicle Assembly Building (VAB), seen behind the tank. External tanks are built by the NASA Michoud Assembly Facility in New Orleans and transported by barge to Cape Canaveral and then up the Banana River to the turn basin in the Launch Complex 39 Area. In the VAB, the tank will await stacking for a future Shuttle mission

  5. KSC-00padig096

    NASA Image and Video Library

    2000-11-21

    KENNEDY SPACE CENTER, FLA. -- A newly arrived external tank heads from the turn basin toward the Vehicle Assembly Building (VAB), seen behind the tank. External tanks are built by the NASA Michoud Assembly Facility in New Orleans and transported by barge to Cape Canaveral and then up the Banana River to the turn basin in the Launch Complex 39 Area. In the VAB, the tank will await stacking for a future Shuttle mission

  6. KSC VAB Aeroacoustic Hazard Assessment

    DTIC Science & Technology

    2010-07-01

    a Mobile Launch Platform (MLP). Several platform levels are used to perform processing operations and will too be reused and/or modified. Each HB is...I/V Flight Vehicles and the VAB The shell is made up of hundreds of aluminum “punch-out” panels which are designed to fail above approximately 100...into several slices which are converted to monopole sources (see figure below). Figure 3: Plume conversion into acoustic sources [2] The

  7. STS-106 orbiter Atlantis rolls over to the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Inside the Vehicle Assembly Building (VAB), overhead cranes move above the orbiter Atlantis in order to lift it to vertical. When vertical, the orbiter will be placed aboard the mobile launcher platform (MLP) for stacking with the solid rocket boosters and external tank. Atlantis is scheduled to launch Sept. 8 on mission STS-106, the fourth construction flight to the International Space Station, with a crew of seven.

  8. KSC-04PD-0017

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Endeavour rolls into the Vehicle Assembly Building (VAB) for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bays cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  9. KSC-04PD-0018

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Endeavour rolls into the Vehicle Assembly Building (VAB) for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bays cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  10. KSC-04pd0660

    NASA Image and Video Library

    2004-03-26

    CAPE CANAVERAL, Fla. -- This aerial photo shows the expanse of the Launch Complex 39 Area, bordered on the east by the Atlantic Ocean and cloud-filled sky. At center right, towering above the surrounding sites, is the Vehicle Assembly Building. To the left, or north, is the Orbiter Processing Facility’s Bay 3. On the western side are OPF Bays 1 and 2. South, near the roadway, is the Operations Support Building. The two-lane crawlerway stretches from the VAB toward the coast, site of Launch Pad 39A, closest, and Launch Pad 39B, far left. Between the VAB and the ocean sprawl the Banana Creek and the Banana River. The turn basin, at right, allows delivery of external tanks that are offloaded close to and transported to the VAB. At the western end of the Turn Basin sits the press mound, home of the NASA KSC News Center. Photo credit: NASA

  11. KSC-05PD-1148

    NASA Technical Reports Server (NTRS)

    2005-01-01

    KENNEDY SPACE CENTER, FLA. Dwarfing the accompanying vehicles, Space Shuttle Discovery, resting on the Mobile Launcher Platform atop the Crawler/Transporter, heads along the crawlerway to the Vehicle Assembly Building (VAB). Discovery is rolling back from Launch Pad 39B (in the background). Once inside the VAB, Discovery will be demated from its External Tank and lifted into the transfer aisle. On or about June 7, Discovery will be lifted and attached to its new tank and Solid Rocket Boosters, which are already in the VAB. Only the 15th rollback in Space Shuttle Program history, the 4.2-mile journey allows additional modifications to be made to the External Tank prior to a safe Return to Flight. Discovery is expected to be rolled back to the launch pad in mid-June for Return to Flight mission STS-114. The launch window extends from July 13 to July 31.

  12. KSC-05PD-1175

    NASA Technical Reports Server (NTRS)

    2005-01-01

    KENNEDY SPACE CENTER, FLA. Space Shuttle Discovery, resting on the Mobile Launcher Platform, turns the corner on the crawlerway as it rolls back from Launch Pad 39B to the Vehicle Assembly Building (VAB) at NASAs Kennedy Space Center. Once inside the VAB, it will be demated from its External Tank and lifted into the transfer aisle. On or about June 7, Discovery will be attached to its new tank and Solid Rocket Boosters, which are already in the VAB. Only the 15th rollback in Space Shuttle Program history, the 4.2-mile journey allows additional modifications to be made to the External Tank prior to a safe Return to Flight. Discovery is expected to be rolled back to the launch pad in mid-June for Return to Flight mission STS-114. The launch window extends from July 13 to July 31. [Photo courtesy of Scott Andrews

  13. The American flag on the VAB is being repainted

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Painters are suspended on platforms from the top of the 525-foot- high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag. The flag spans an area 209 feet by 110 feet and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. In addition to the flag, the Bicentennial Emblem on the other side of the VAB doors is being replaced by the NASA logo, honoring NASA's 40th anniversary (in October). The logo covers an area 110 feet by 132 feet. Work is expected to be completed in mid-September.

  14. Repainting of the VAB continues

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Painters are suspended on platforms from the top of the 525-foot- high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag and NASA logo. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet, and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The previous Bicentennial Emblem on the right side of the VAB doors is being replaced by the NASA logo, honoring NASA's 40th anniversary (in October). The logo will cover an area 110 feet by 132 feet, or about 12,300 square feet. The painting platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. Work is expected to be completed in mid-September.

  15. The American flag on the VAB is being repainted

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Painters are suspended on platforms from the top of the 525-foot- high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag and NASA logo. The flag spans an area 209 feet by 110 feet and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The previous Bicentennial Emblem on the other side of the VAB doors is being replaced by the NASA logo, honoring NASA's 40th anniversary (in October). The logo covers an area 110 feet by 132 feet. The painting platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. Work is expected to be completed in mid-September.

  16. Absorption Voltages and Insulation Resistance in Ceramic Capacitors with Cracks

    NASA Technical Reports Server (NTRS)

    Teverovsky, Alexander

    2016-01-01

    Time dependence of absorption voltages (Vabs) in different types of low-voltage X5R and X7R ceramic capacitors was monitored for a maximum duration of hundred hours after polarization. To evaluate the effect of mechanical defects on Vabs, cracks in the dielectric were introduced either mechanically or by thermal shock. The maximum absorption voltage, time to roll-off, and the rate of voltage decrease are shown to depend on the crack-related leakage currents and insulation resistance in the parts. A simple model that is based on the Dow equivalent circuit for capacitors with absorption has been developed to assess the insulation resistance of capacitors. Standard measurements of the insulation resistance, contrary to the measurements based on Vabs, are not sensitive to the presence of mechanical defects and fail to reveal capacitors with cracks. Index Terms: Ceramic capacitor, insulation resistance, dielectric absorption, cracking.

  17. KSC-98pc987

    NASA Image and Video Library

    1998-08-28

    KENNEDY SPACE CENTER, FLA. -- The NASA logo, also known as the "meatball," is painted on the side of the Vehicle Assembly Building (VAB). When finished, the logo will measure 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. In addition to the logo, the American flag is also being repainted on the other side of the VAB. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. The painting honors NASA’s 40th anniversary on Oct. 1 and is expected to be complete in mid-September

  18. KSC-98pc989

    NASA Image and Video Library

    1998-08-28

    KENNEDY SPACE CENTER, FLA. -- Painters are dwarfed by the six-foot stars in the blue field of the American flag they are repainting on the side of the Vehicle Assembly Building (VAB). The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. In addition to the flag, the NASA logo, also known as the "meatball," is being painted on the VAB. When finished, the logo will measure 110 feet by 132 feet, or about 12,300 square feet. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. The painting honors NASA’s 40th anniversary on Oct. 1 and is expected to be complete in mid-September

  19. KSC-2011-6400

    NASA Image and Video Library

    2011-08-11

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttles Discovery and Endeavour, their noses encased in protective plastic where their forward reaction control systems (FRCS) once resided, pause outside Orbiter Processing Facility-3 (OPF-3) for a unique photo opportunity. Discovery, which temporarily was being stored in the Vehicle Assembly Building (VAB), is switching places with Endeavour, which has been undergoing decommissioning in OPF-1. Discovery then will be rolled into OPF-1 and Endeavour into the VAB. In OPF-1, Discovery will undergo further preparations for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. Endeavour will be stored in the VAB until October when it will be moved into OPF-2 for further work to get it ready for public display at the California Science Center in Los Angeles. For more information, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jim Grossmann

  20. Different dissecting orders of the pulmonary bronchus and vessels during right upper lobectomy are associated with surgical feasibility and postoperative recovery for lung cancer patients.

    PubMed

    Zhai, Hao-Ran; Yang, Xue-Ning; Nie, Qiang; Liao, Ri-Qiang; Dong, Song; Li, Wei; Jiang, Ben-Yuan; Yang, Jin-Ji; Zhou, Qing; Tu, Hai-Yan; Zhang, Xu-Chao; Wu, Yi-Long; Zhong, Wen-Zhao

    2017-06-27

    Right upper lobectomy (RUL) for lung cancer with different dissecting orders involves the most variable anatomical structures, but no studies have analyzed its effects on postoperative recovery. This study compared the conventional surgical approach, VAB (dissecting pulmonary vessels first, followed by the bronchus), and the alternative surgical approach, aBVA (dissecting the posterior ascending arterial branch first, followed by the bronchus and vessels) on improving surgical feasibility and postoperative recovery for lung cancer patients. According to the surgical approach, consecutive lung cancer patients undergoing RUL were grouped into aBVA and VAB cohorts. Their clinical, pathologic, and perioperative characteristics were collected to compare perioperative outcomes. Three hundred one patients were selected (109 in the aBVA cohort and 192 in the VAB cohort). The mean operation time was shorter in the aBVA cohort than in the VAB cohort (164 vs. 221 min, P < 0.001), and less blood loss occurred in the aBVA cohort (92 vs. 141 mL, P < 0.001). The rate of conversion to thoracotomy was lower in the aBVA cohort than in the VAB cohort (0% vs. 11.5%, P < 0.001). The mean duration of postoperative chest drainage was shorter in the aBVA cohort than in the VAB cohort (3.6 vs. 4.5 days, P = 0.001). The rates of postoperative complications were comparable (P = 0.629). The median overall survival was not arrived in both cohorts (P > 0.05). The median disease-free survival was comparable for all patients in the two cohorts (not arrived vs. 41.97 months) and for patients with disease recurrences (13.25 vs. 9.44 months) (both P > 0.05). The recurrence models in two cohorts were also comparable for patients with local recurrences (6.4% vs. 7.8%), distant metastases (10.1% vs. 8.3%), and both (1.8% vs. 1.6%) (all P > 0.05). Dissecting the right upper bronchus before turning over the lobe repeatedly and dissecting veins via the aBVA approach during RUL would promote surgical feasibility and achieve comparable postoperative recovery for lung cancer patients.

  1. KSC-02pd1148

    NASA Image and Video Library

    2002-07-25

    KENNEDY SPACE CENTER, FLA. -- In Vehicle Assembly Building (VAB) high bay 4, installation of a Payload Bay Door Drying Enclosure is in progress. The enclosure will keep moisture from being absorbed into the graphite epoxy used on the payload bay doors of the Shuttle orbiters with the assistance of mini-Portable Purge Units (PPUs). Once in operation, the enclosure will allow NASA the option to store an orbiter in the VAB bay up to 180 days in a "standby-to-stack" mode.

  2. KSC-02pd1147

    NASA Image and Video Library

    2002-07-25

    KENNEDY SPACE CENTER, FLA. -- In Vehicle Assembly Building (VAB) high bay 4, installation of a Payload Bay Door Drying Enclosure is in progress. The enclosure will keep moisture from being absorbed into the graphite epoxy used on the payload bay doors of the Shuttle orbiters with the assistance of mini-Portable Purge Units (PPUs). Once in operation, the enclosure will allow NASA the option to store an orbiter in the VAB bay up to 180 days in a "standby-to-stack" mode.

  3. KSC-02pd1150

    NASA Image and Video Library

    2002-07-26

    KENNEDY SPACE CENTER, FLA. -- -- In Vehicle Assembly Building (VAB) high bay 4, installation of a Payload Bay Door Drying Enclosure is in progress. The enclosure will keep moisture from being absorbed into the graphite epoxy used on the payload bay doors of the Shuttle orbiters with the assistance of mini-Portable Purge Units (PPUs). Once in operation, the enclosure will allow NASA the option to store an orbiter in the VAB bay up to 180 days in a "standby-to-stack" mode.

  4. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    The Orion heat shield from Exploration Flight Test-1 has arrived in High Bay 2 of the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  5. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    Inside High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, the Orion heat shield from Exploration Flight Test-1 is secured on foam blocks. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  6. KSC-04PD-0019

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Endeavour settles into place inside the Vehicle Assembly Building (VAB) where it has been moved for temporary storage. It left the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bays cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  7. Engineering Management Board tour Vehicle Assembly Building (VAB)

    NASA Image and Video Library

    2017-03-22

    All the heads of engineering from across the country come together at KSC for a bi-annual face to face meeting to discuss roles, progress and capabilities. The two day meeting helps to ensure a unified focus in all engineering endevours, especially those that involve intercenter collaboration such as upcoming launch of SLS and Orion. The group toured level 1 and 28 of highbay 3 of the VAB on Wednesday, March 22 to look over the newly installed platforms.

  8. Cabana Multi-User Spaceport Tour of KSC

    NASA Image and Video Library

    2017-02-17

    Kennedy Space Center Director Bob Cabana speaks to members of the news media on the balcony of Operations Support Building II describing the site's transition from a primarily government-only facility to a premier, multi-user spaceport. In the background is the Vehicle Assembly Building (VAB). Modifications were recently completed in the VAB where new work platforms were installed to support processing of NASA's Space Launch System rocket designed to send the Orion spacecraft on missions beyond low-Earth orbit.

  9. KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-17

    KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  10. KENNEDY SPACE CENTER, FLA. - The crawler transporter has slowly moved the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, out of the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-17

    KENNEDY SPACE CENTER, FLA. - The crawler transporter has slowly moved the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, out of the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  11. KENNEDY SPACE CENTER, FLA. - The crawler transporter is slowly moving the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, out of the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-17

    KENNEDY SPACE CENTER, FLA. - The crawler transporter is slowly moving the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, out of the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  12. KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, out of the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-17

    KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, out of the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  13. STS-79 Atlantis approaches the VAB (view from inside VAB)

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The Space Shuttle Atlantis begins its move into the Vehicle Assembly Building for shelter from the effects of Hurricane Fran. Atlantis is completing its rollback from Launch Pad 39A, where it was undergoing preparations for Mission STS-79. This marks the second rollback for Atlantis since July because of hurricane threats. The threat of Hurricane Bertha forced the rollback of Atlantis in July. Atlantis currently is scheduled for launch on the fourth Shuttle-Mir docking mission around mid-September.

  14. KSC-01pp1187Crop

    NASA Image and Video Library

    2001-06-20

    CAPE CANAVERAL, Fla. – An aerial view of Launch Complex 39 shows the south and west sides of the Vehicle Assembly Building. The curved roadway heading to the VAB leads to high bay 2, the Safe Haven facility constructed in 2000. Beyond it is the Orbiter Processing Facility, bays 1 and 2. The OPF bay 3 is farther still, closer to the VAB. Farther in the background are the waters of the Banana Creek in the Merritt Island National Wildlife Refuge. Photo credit: NASA

  15. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    Inside High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, a worker monitors the progress as a crane lowers the Orion heat shield from Exploration Flight Test-1 onto foam blocks. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  16. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    Inside High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers monitor the progress as a crane lowers the Orion heat shield from Exploration Flight Test-1 onto foam blocks. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  17. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    Inside High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, a crane is attached to the Orion heat shield from Exploration Flight Test-1 for unloading off its transporter. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  18. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    Inside High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers help prepare the Orion heat shield from Exploration Flight Test-1 for unloading off its transporter. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  19. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    Inside High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, a worker helps prepare the Orion heat shield from Exploration Flight Test-1 for unloading off its transporter. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  20. KSC-04PD-0016

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Endeavour is towed in front of the Vehicle Assembly Building (VAB) where it is going for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bays cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  1. KSC-04PD-0015

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Endeavour is towed in front of the Vehicle Assembly Building (VAB) where it is going for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bays cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  2. Crawler Transporter 2 Trek

    NASA Image and Video Library

    2016-03-23

    NASA’s upgraded crawler-transporter 2 (CT-2) begins its trek from the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida to Launch Pad 39B to test recently completed upgrades and modifications for NASA’s journey to Mars. The Ground Systems Development and Operations Program at Kennedy oversaw upgrades to the crawler in the VAB. The crawler will carry the mobile launcher with Orion atop the Space Launch System rocket to Pad 39B for Exploration Mission-1, scheduled for 2018.

  3. Crawler Transporter 2 Trek

    NASA Image and Video Library

    2016-03-23

    NASA’s upgraded crawler-transporter 2 (CT-2) has exited the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida for its trek along the crawlerway to Launch Pad 39B to test recently completed upgrades and modifications for NASA’s journey to Mars. The Ground Systems Development and Operations Program at Kennedy oversaw upgrades to the crawler in the VAB. The crawler will carry the mobile launcher with Orion atop the Space Launch System rocket to Pad 39B for Exploration Mission-1, scheduled for 2018.

  4. Crawler Transporter 2 Trek

    NASA Image and Video Library

    2016-03-23

    NASA’s upgraded crawler-transporter 2 (CT-2) travels along the crawlerway from the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida on its trek to Launch Pad 39B to test recently completed upgrades and modifications for NASA’s journey to Mars. The Ground Systems Development and Operations Program at Kennedy oversaw upgrades to the crawler in the VAB. The crawler will carry the mobile launcher with Orion atop the Space Launch System rocket to Pad 39B for Exploration Mission-1, scheduled for 2018.

  5. Cabana Multi-User Spaceport Tour of KSC

    NASA Image and Video Library

    2017-02-17

    Nancy Bray, director of Spaceport Integration and Services at NASA's Kennedy Space Center, speaks to members of the news media on the balcony of Operations Support Building II describing the site's transition from a primarily government-only facility to a premier, multi-user spaceport. In the background is the Vehicle Assembly Building (VAB). Modifications were recently completed in the VAB where new work platforms were installed to support processing of NASA's Space Launch System rocket designed to send the Orion spacecraft on missions beyond low-Earth orbit.

  6. Cabana Multi-User Spaceport Tour of KSC

    NASA Image and Video Library

    2017-02-17

    Tom Engler, director of Center Planning and Development at NASA's Kennedy Space Center, speaks to members of the news media on the balcony of Operations Support Building II describing the site's transition from a primarily government-only facility to a premier, multi-user spaceport. In the background is the Vehicle Assembly Building (VAB). Modifications were recently completed in the VAB where new work platforms were installed to support processing of NASA's Space Launch System rocket designed to send the Orion spacecraft on missions beyond low-Earth orbit.

  7. Ground level view of Apollo 14 space vehicle leaving VAB for launch pad

    NASA Image and Video Library

    1970-11-09

    S70-54121 (9 Nov. 1970) --- A ground level view at Launch Complex 39, Kennedy Space Center (KSC), showing the Apollo 14 (Spacecraft 110/Lunar Module 8/Saturn 509) space vehicle leaving the Vehicle Assembly Building (VAB). The Saturn V stack and its mobile launch tower, atop a huge crawler-transporter, were rolled out to Pad A. The Apollo 14 crewmen will be astronauts Alan B. Shepard Jr., commander; Stuart A. Roosa, command module pilot; and Edgar D. Mitchell, lunar module pilot.

  8. KSC-04pd2029

    NASA Image and Video Library

    2004-09-30

    KENNEDY SPACE CENTER, FLA. - A closeup of the Vehicle Assembly Building shows one of the scaffolds being used to allow workers to cover the holes with corrugated steel so the facility can be returned to performing operational activities. Xenon lights on the ground provide the illumination. The VAB lost 820 panels from the south wall during Frances, and 25 additional panels during Hurricane Jeanne. The VAB stands 525 feet tall. Central Florida, including Kennedy Space Center, was battered by four hurricanes between Aug. 13 and Sept. 26.

  9. KSC-04pd2026

    NASA Image and Video Library

    2004-09-30

    KENNEDY SPACE CENTER, FLA. - The south wall of the Vehicle Assembly Building is bathed in light at night to allow workers on a scaffold to cover the holes with corrugated steel so the facility can be returned to performing operational activities. Xenon lights on the ground provide the illumination. The VAB lost 820 panels from the south wall during Frances, and 25 additional panels during Hurricane Jeanne. The VAB stands 525 feet tall. Central Florida, including Kennedy Space Center, was battered by four hurricanes between Aug. 13 and Sept. 26.

  10. KSC-04pd2025

    NASA Image and Video Library

    2004-09-30

    KENNEDY SPACE CENTER, FLA. - Xenon lights on the ground near the Vehicle Assembly Building bathe the south wall in light, allowing workers on scaffolds (center and upper right near the NASA logo) to cover the holes with corrugated steel so the facility can be returned to performing operational activities. The VAB lost 820 panels from the south wall during Frances, and 25 additional panels during Hurricane Jeanne. The VAB stands 525 feet tall. Central Florida, including Kennedy Space Center, was battered by four hurricanes between Aug. 13 and Sept. 26.

  11. KSC-04PD-2025

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Xenon lights on the ground near the Vehicle Assembly Building bathe the south wall in light, allowing workers on scaffolds (center and upper right near the NASA logo) to cover the holes with corrugated steel so the facility can be returned to performing operational activities. The VAB lost 820 panels from the south wall during Frances, and 25 additional panels during Hurricane Jeanne. The VAB stands 525 feet tall. Central Florida, including Kennedy Space Center, was battered by four hurricanes between Aug. 13 and Sept. 26.

  12. C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.

    PubMed

    Kanteti, Rajani; Dhanasingh, Immanuel; El-Hashani, Essam; Riehm, Jacob J; Stricker, Thomas; Nagy, Stanislav; Zaborin, Alexander; Zaborina, Olga; Biron, David; Alverdy, John C; Im, Hae Kyung; Siddiqui, Shahid; Padilla, Pamela A; Salgia, Ravi

    2016-01-01

    We previously investigated MET and its oncogenic mutants relevant to lung cancer in C. elegans. The inactive orthlogues of the receptor tyrosine kinase Eph and MET, namely vab-1 and RB2088 respectively, the temperature sensitive constitutively active form of KRAS, SD551 (let-60; GA89) and the inactive c-CBL equivalent mutants in sli-1 (PS2728, PS1258, and MT13032) when subjected to chronic exposure of nicotine resulted in a significant loss in egg-laying capacity and fertility. While the vab-1 mutant revealed increased circular motion in response to nicotine, the other mutant strains failed to show any effect. Overall locomotion speed increased with increasing nicotine concentration in all tested mutant strains except in the vab-1 mutants. Moreover, chronic nicotine exposure, in general, upregulated kinases and phosphatases. Taken together, these studies provide evidence in support of C. elegans as initial in vivo model to study nicotine and its effects on oncogenic mutations identified in humans.

  13. KSC-98pc990

    NASA Image and Video Library

    1998-08-28

    KENNEDY SPACE CENTER, FLA. -- The worker on the lower left applies the red paint to the chevron while the worker on the right fills in the blue field to the NASA logo they are painting on the Vehicle Assembly Building (VAB). When finished, the logo, also known as the "meatball," will measure 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. In addition to the logo, the American flag is being repainted on the other side of the VAB. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The painting honors NASA’s 40th anniversary on Oct. 1 and is expected to be complete in mid-September

  14. KSC-98pc991

    NASA Image and Video Library

    1998-08-28

    KENNEDY SPACE CENTER, FLA. -- The worker on the lower left applies the red paint to the chevron while the worker on the right fills in the blue field to the NASA logo they are painting on the Vehicle Assembly Building (VAB). When finished, the logo, also known as the "meatball," will measure 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls. In addition to the logo, the American flag is being repainted on the other side of the VAB. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The painting honors NASA’s 40th anniversary on Oct. 1 and is expected to be complete in mid-September

  15. Novel vascular endothelial growth factor blocker improves cellular viability and reduces hypobaric hypoxia-induced vascular leakage and oedema in rat brain.

    PubMed

    Saraswat, Deepika; Nehra, Sarita; Chaudhary, Kamal; CVS, Siva Prasad

    2015-05-01

    Vascular endothelial growth factor (VEGF) is an important cerebral angiogenic and permeability factor under hypoxia. There is a need to find effective molecules that may ameliorate hypoxia-induced cerebral oedema. In silico identification of novel candidate molecules that block VEGF-A site were identified and validated with a Ramachandran plot. The active site residues of VEGF-A were detected by Pocketfinder, CASTp, and DogSiteScorer. Based on in silico data, three VEGF-A blocker (VAB) candidate molecules (VAB1, VAB2, and VAB3) were checked for improvement in cellular viability and regulation of VEGF levels in N2a cells under hypoxia (0.5% O2 ). Additionally, the best candidate molecule's efficacy was assessed in male Sprague-Dawley rats for its ameliorative effect on cerebral oedema and vascular leakage under hypobaric hypoxia 7260 m. All experimental results were compared with the commercially available VEGF blocker sunitinib. Vascular endothelial growth factor-A blocker 1 was found most effective in increasing cellular viability and maintaining normal VEGF levels under hypoxia (0.5% oxygen) in N2a cells. Vascular endothelial growth factor-A blocker 1 effectively restored VEGF levels, decreased cerebral oedema, and reduced vascular leakage under hypobaric hypoxia when compared to sunitinib-treated rats. Vascular endothelial growth factor-A blocker 1 may be a promising candidate molecule for ameliorating hypobaric hypoxia-induced vasogenic oedema by regulating VEGF levels. © 2015 Wiley Publishing Asia Pty Ltd.

  16. KENNEDY SPACE CENTER, FLA. - Mobile Launcher Platform (MLP) number 3 and a set of twin solid rocket boosters, atop the crawler-transporter, inch away from the Vehicle Assembly Building (VAB) in support of the second engineering analysis vibration test on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB, travels toward Launch Pad 39A and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-21

    KENNEDY SPACE CENTER, FLA. - Mobile Launcher Platform (MLP) number 3 and a set of twin solid rocket boosters, atop the crawler-transporter, inch away from the Vehicle Assembly Building (VAB) in support of the second engineering analysis vibration test on the crawler and MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB, travels toward Launch Pad 39A and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  17. Atlantis returns to VAB after beginning rollout to the pad

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. -- Scattered clouds cast shadows as Space Shuttle Atlantis crawls back inside the Vehicle Assembly Building high bay 1. After earlier starting its trek to Launch Pad 39B, Atlantis was returned to the VAB due to lightning in the area. To the left of the VAB is the Launch Control Center. The four-story building houses the firing rooms that are used to conduct Space Shuttle launches. Leading away from the VAB, in the foreground, is the crawlerway, the 130-foot-wide road specially constructed to transport the Shuttle, mobile launcher platform and crawler-transporter with a combined weight of about 17 million pounds. Space Shuttle Atlantis is targeted for launch no earlier than July 12 on mission STS-104, the 10th flight to the International Space Station. The payload on the 11-day mission is the Joint Airlock Module, which will allow astronauts and cosmonauts in residence on the Station to perform future spacewalks without the presence of a Space Shuttle. The module, which comprises a crew lock and an equipment lock, will be connected to the starboard (right) side of Node 1 Unity. Atlantis will also carry oxygen and nitrogen storage tanks, vital to operation of the Joint Airlock, on a Spacelab Logistics Double Pallet in the payload bay. The tanks, to be installed on the perimeter of the Joint Module during the missions spacewalks, will support future spacewalk operations and experiments plus augment the resupply system for the Stations Service Module.

  18. Tolerability, Safety, and Benefits of Risperidone in Children and Adolescents with Autism: 21-Month Follow-up After 8-Week Placebo-Controlled Trial

    PubMed Central

    Rettiganti, Mallikarjuna; Nagaraja, Haikady N.; Hollway, Jill A.; McCracken, James; McDougle, Christopher J.; Tierney, Elaine; Scahill, Lawrence; Arnold, L. Eugene; Hellings, Jessica; Posey, David J.; Swiezy, Naomi B.; Ghuman, Jaswinder; Grados, Marco; Shah, Bhavik; Vitiello, Benedetto

    2015-01-01

    Abstract Objective: Risperidone has demonstrated efficacy for acute (8 week) and intermediate length (6 month) management of severe irritability and aggression in children and adolescents with autism. Less is known about the long-term effects of risperidone exposure in this population. We examined the tolerability, safety, and therapeutic benefit of risperidone exposure over a 1–2 year follow-up period. Methods: In a naturalistic study, 84 children and adolescents 5–17 years of age (from an original sample of 101) were assessed an average of 21.4 months after initial entry into a placebo-controlled 8 week trial of risperidone for children and adolescents with autism and severe irritability. They were assessed at baseline and at follow-up on safety and tolerability measures (blood, urinalysis, electrocardiogram [ECG], medical history, vital signs, neurological symptoms, other adverse events), developmental measures (adaptive behavior, intelligence quotient [IQ]), and standardized rating instruments. Treatment over the follow-up period, after completion of protocol participation, was uncontrolled. Statistical analyses assessed outcome over time with or without prolonged risperidone therapy. Results: Two-thirds of the 84 subjects continued to receive risperidone (mean 2.47 mg/day, S.D. 1.29 mg). At follow-up, risperidone was associated with more enuresis, more excessive appetite, and more weight gain, but not more adverse neurological effects. No clinically significant events were noted on blood counts, chemistries, urinalysis, ECG, or interim medical history. Regardless of drug condition at follow-up, there was considerable improvement in maladaptive behavior compared with baseline, including core symptoms associated with autism. Height and weight gains were elevated with risperidone. Social skills on Vineland Adaptive Behavior Scale (VABS) improved with risperidone. Parent-rated Aberrant Behavior Checklist (ABC) Irritability subscale scores were reduced in those taking risperidone at follow-up. Several other measures of maladaptive behavior (some related to socialization) also showed improved functioning in association with risperidone on the ABC or on the Modified Real Life Rating Scale. Conclusions: Increased appetite, weight gain, and enuresis are risks associated with long-term risperidone. Our data suggest that these risks were balanced by longer-term behavioral and social benefits for many children over 1.8 years of ongoing treatment. PMID:26262903

  19. Parent-child communication and psychological adjustment in children with a brain tumor.

    PubMed

    Adduci, Annarita; Jankovic, Momcilo; Strazzer, Sandra; Massimino, Maura; Clerici, Carlo; Poggi, Geraldina

    2012-08-01

    Internalizing problems, anxiety, depression, withdrawal, and consequent social problems are frequently observed in children with brain tumors. The objective of this work is to describe the relationship between these psychological problems and the type of parent-child communication established about the disease. A group of 64 children surviving a brain tumor (aged 4-18 years) underwent psychological assessment by means of parent reports on the Child Behavior Checklist (CBCL) and the Vineland Adaptive Behavior Scales (VABS). A semi-structured interview with each child and their parents enabled us to classify the method of communication regarding the disease as "avoidance," "ineffective," and "effective." Demographic, clinical, and functional data relating to the disease were also collected. A significant relationship between the onset of Internalizing problems, withdrawal, anxiety-depression, and social problems and the presence of avoidance or ineffective communication about the disease was observed (P = 0.001, P = 0.001, P = 0.001, and P = 0.01, respectively). These psychological problems did not prove to be associated to demographic or clinical variables; however, they were found to be related to the children's residual functional problems. By contrast, the method of communication proved to be unrelated to clinical or functional variables, but it was associated to demographic variables such as sex and age at assessment. Effective (complete, truthful, consistent, comprehensible, gradual and continuous, and tailored) communication to the child about his/her condition proved to be associated with a better psychological outcome. Copyright © 2012 Wiley Periodicals, Inc.

  20. KSC-01pp1187

    NASA Image and Video Library

    2001-06-20

    KENNEDY SPACE CENTER, Fla. -- An aerial view of Launch Complex 39 shows the south and west sides of the Vehicle Assembly Building. The curved roadway heading to the VAB leads to the high bay 2, the Safe Haven facility constructed in 2000. The white building in the foreground is the Processing Control Center. Beyond it is the Orbiter Processing Facility, bays 1 and 2. The OPF bay 3 is farther still, closer to the VAB. Farther in the background are the waters of Banana Creek in the Merritt Island National Wildlife Refuge

  1. Orion EFT-1 Heat Shield Offload from Truck onto Foam Pads (Dunna

    NASA Image and Video Library

    2017-04-27

    Inside High Bay 2 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, a crane lifts the Orion heat shield from Exploration Flight Test-1 up off its transporter. It will be lowered onto foam blocks. The heat shield is being transferred from the Orion Program to the Ground Systems Development and Operations Program, Landing and Recovery Operations. In the VAB, the heat shield will be integrated with the Orion ground test article and used for future underway recovery testing.

  2. KSC-2010-5333

    NASA Image and Video Library

    2010-10-27

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, a crawler-transporter moves a mobile launcher platform with two solid rocket boosters perched on top from the Vehicle Assembly Building's (VAB) High Bay 1 to High Bay 3. Inside the VAB, the boosters will be joined to an external fuel tank next month in preparation for space shuttle Endeavour's STS-134 mission to the International Space Station targeted to launch in February, 2011. For more information visit: http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html Photo credit: NASA/Jim Grossmann

  3. KSC-2010-5334

    NASA Image and Video Library

    2010-10-27

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, a crawler-transporter moves a mobile launcher platform with two solid rocket boosters perched on top from the Vehicle Assembly Building's (VAB) High Bay 1 to High Bay 3. Inside the VAB, the boosters will be joined to an external fuel tank next month in preparation for space shuttle Endeavour's STS-134 mission to the International Space Station targeted to launch in February, 2011. For more information visit: http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html Photo credit: NASA/Jim Grossmann

  4. KSC-2009-6803

    NASA Image and Video Library

    2009-12-14

    CAPE CANAVERAL, Fla. – At NASA's Kennedy Space Center in Florida, dense fog moving ashore from the Atlantic Ocean engulfs the Vehicle Assembly Building on an atypical December afternoon. It is the second time in one day that fog has obscured the top of the 525-foot-tall processing facility, known as the VAB. Space Shuttle Endeavour currently is in the VAB's High Bay 1 where it is being attached to its external fuel tank and solid rocket boosters in preparation for its targeted launch in early February 2010. Photo credit: NASA/Jack Pfaller

  5. KSC-2010-5336

    NASA Image and Video Library

    2010-10-27

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, a crawler-transporter moves a mobile launcher platform with two solid rocket boosters perched on top from the Vehicle Assembly Building's (VAB) High Bay 1 to High Bay 3. Inside the VAB, the boosters will be joined to an external fuel tank next month in preparation for space shuttle Endeavour's STS-134 mission to the International Space Station targeted to launch in February, 2011. For more information visit: http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html Photo credit: NASA/Ben Cooper

  6. KSC-2010-5337

    NASA Image and Video Library

    2010-10-27

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, a crawler-transporter moves a mobile launcher platform with two solid rocket boosters perched on top from the Vehicle Assembly Building's (VAB) High Bay 1 to High Bay 3. Inside the VAB, the boosters will be joined to an external fuel tank next month in preparation for space shuttle Endeavour's STS-134 mission to the International Space Station targeted to launch in February, 2011. For more information visit: http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html Photo credit: NASA/Ben Cooper

  7. KSC-2010-5335

    NASA Image and Video Library

    2010-10-27

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, a crawler-transporter moves a mobile launcher platform with two solid rocket boosters perched on top from the Vehicle Assembly Building's (VAB) High Bay 1 to High Bay 3. Inside the VAB, the boosters will be joined to an external fuel tank next month in preparation for space shuttle Endeavour's STS-134 mission to the International Space Station targeted to launch in February, 2011. For more information visit: http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html Photo credit: NASA/Jim Grossmann

  8. KSC-03PD-3196

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis approaches the Vehicle Assembly Building (VAB). It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  9. KSC-04PD-0013

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- After Endeavours rollout from inside the Orbiter Processing Facility, the transporter (foreground) prepares to tow it to the Vehicle Assembly Building for temporary transfer. A protective cover surrounds the nose of Endeavour. The move to the VAB allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bays cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  10. KSC-03PD-3194

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  11. KSC-03PD-3197

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis nears the Vehicle Assembly Building (VAB). It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  12. KSC-03PD-3189

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis awaits transport from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  13. Crawler Transporter 2 Trek

    NASA Image and Video Library

    2016-03-23

    Technicians walk alongside NASA’s upgraded crawler-transporter 2 (CT-2) as it continues the trek on the crawlerway from the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida to Launch Pad 39B to test recently completed upgrades and modifications for NASA’s journey to Mars. The Ground Systems Development and Operations Program at Kennedy oversaw upgrades to the crawler in the VAB. The crawler will carry the mobile launcher with Orion atop the Space Launch System rocket to Pad 39B for Exploration Mission-1, scheduled for 2018.

  14. Crawler Transporter 2 Trek

    NASA Image and Video Library

    2016-03-23

    Technicians walk alongside NASA’s upgraded crawler-transporter 2 (CT-2) as it continues the trek along the crawlerway from the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida to Launch Pad 39B to test recently completed upgrades and modifications for NASA’s journey to Mars. The Ground Systems Development and Operations Program at Kennedy oversaw upgrades to the crawler in the VAB. The crawler will carry the mobile launcher with Orion atop the Space Launch System rocket to Pad 39B for Exploration Mission-1, scheduled for 2018.

  15. Crawler Transporter 2 Trek

    NASA Image and Video Library

    2016-03-23

    A truck sprays water in front of NASA’s upgraded crawler-transporter 2 (CT-2) to control dust as it begins the trek from the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida to Launch Pad 39B to test recently completed upgrades and modifications for NASA’s journey to Mars. The Ground Systems Development and Operations Program at Kennedy oversaw upgrades to the crawler in the VAB. The crawler will carry the mobile launcher with Orion atop the Space Launch System rocket to Pad 39B for Exploration Mission-1, scheduled for 2018.

  16. Cabana Multi-User Spaceport Tour of KSC

    NASA Image and Video Library

    2017-02-17

    Members of the news media view the 10 levels of new work platforms in High Bay 3 inside the Vehicle Assembly Building (VAB) during a tour of NASA's Kennedy Space Center in Florida with Center Director Bob Cabana. The final platform, A north, was recently installed. The platforms will surround the Space Launch System and Orion spacecraft on the mobile launcher during processing to prepare for the first test flight. The Ground Systems Development and Operations Program is overseeing upgrades to the VAB, including installation of the new work platforms.

  17. View of the Apollo 10 space vehicle at Pad B, ready for launch

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Ground-level view at sunset of the Apollo 10 (Spacecraft 106/Lunar Module 4/Saturn 505) space vehicle at Pad B, Launch Complex 39, Kennedy Space Center. The Apollo 10 stack had just been positioned after being rolled out from the Vehicle Assemble Building (VAB) (34318); View of the Apollo 10 space vehicle (through palm trees and across water) on the way from the VAB to Pad B, Launch Complex 39. The Saturn V and its mobile launch tower are atop a crawler-transporter (34319).

  18. STS-83 Columbia Rollout to PAD-39A (fish eye view in VAB)

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The Space Shuttle Orbiter Columbia begins its rollout from the Vehicle Assembly Building (VAB) to Launch Pad 39A in preparation for the STS-83 mission. The Microgravity Science Laboratory-1 (MSL-1) Spacelab module is the primary payload on this 16-day space flight. The MSL-1 will be used to test some of the hardware, facilities and procedures that are planned for use on the International Space Station while the seven-member flight crew conducts combustion, protein crystal growth and materials processing experiments.

  19. VAB Flag Painting

    NASA Image and Video Library

    2002-01-01

    On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the U.S. flag on the southwest side of the Vehicle Assembly Building. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo is also being painted. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary.

  20. KSC-04pd2027

    NASA Image and Video Library

    2004-09-30

    KENNEDY SPACE CENTER, FLA. - The south wall of the Vehicle Assembly Building is bathed in light at night to allow workers on a scaffold (at left) to cover the holes with corrugated steel so the facility can be returned to performing operational activities. Xenon lights on the ground provide the illumination. The VAB lost 820 panels from the south wall during Frances, and 25 additional panels during Hurricane Jeanne. The VAB stands 525 feet tall. Central Florida, including Kennedy Space Center, was battered by four hurricanes between Aug. 13 and Sept. 26.

  1. Flat epithelial atypia: conservative management of patients without residual microcalcifications post-vacuum-assisted breast biopsy.

    PubMed

    Schiaffino, Simone; Gristina, Licia; Villa, Alessandro; Tosto, Simona; Monetti, Francesco; Carli, Franca; Calabrese, Massimo

    2018-01-01

    To determine the malignancy rate (defined in this study as stability or absence of malignancy developed on close imaging follow-up post-biopsy) of conservative management in patients with a vacuum-assisted breast biopsy (VAB) diagnosis of flat epithelial atypia (FEA), performed on single group of microcalcifications, completely removed during procedure. This is a retrospective, monocentric, observational study, approved by IRB. Inclusion criteria were: VAB performed on a single group of microcalcifications; the absence of residual calcifications post-VAB; diagnosis of isolated FEA as the most advanced proliferative lesion; radiological follow-up at least of 12 months. The personal history of breast cancer or other high-risk lesions was an exclusion criteria. The patients enrolled were conservatively managed, without surgical excision, through close follow-up: the first two mammographies performed with an interval of 6 months after biopsy, followed by annual mammographic and clinical checks. 48 consecutive patients were enrolled in the study, all females, with age range of 39-76 years (mean 53,3 years) and radiological follow-up range of 13-75 months (mean 41.5 months). All the lesions were classified as BI-RADS 4b. The diameter range of the group of calcifications was 3-10 mm (mean 5, 6 mm). In each patient, 7 to 15 samples (mean 11) were obtained. Among all the patients, there was only one case (2%) of new microcalcifications, developed in the same breast, 26 months after and 8 mm from the site of previous VAB, and interpreted as ADH at surgical excision. All the checks of the other patients were negative. Even with a limited follow-up, we found a malignancy rate lower than 2%, through a defined population. Further studies with bigger number of patients and extended follow-up are needed to reinforce this hypothesis. Advances in knowledge: Surgical excision may not be necessary in patients with VAB diagnosis of isolated FEA, without residual microcalcifications post-procedure and considered concordant with the mammographic presentation, considering the low rate of malignancy at subsequent follow-ups.

  2. Vacuum-assisted breast biopsy with 7-gauge, 8-gauge, 9-gauge, 10-gauge, and 11-gauge needles: how many specimens are necessary?

    PubMed

    Preibsch, Heike; Baur, Astrid; Wietek, Beate M; Krämer, Bernhard; Staebler, Annette; Claussen, Claus D; Siegmann-Luz, Katja C

    2015-09-01

    Published national and international guidelines and consensus meetings on the use of vacuum-assisted biopsy (VAB) give different recommendations regarding the required numbers of tissue specimens depending on needle size and imaging method. To evaluate the weights of specimens obtained with different VAB needles to facilitate the translation of the required number of specimens between different breast biopsy systems and needle sizes, respectively. Five different VAB systems and seven different needle sizes were used: Mammotome® (11-gauge (G), 8-G), Vacora® (10-G), ATEC Sapphire™ (9-G), 8-G Mammotome® Revolve™, and EnCor Enspire® (10-G, 7-G). We took 24 (11-G) or 20 (7-10-G) tissue cores from a turkey breast phantom. The mean weight of a single tissue core was calculated for each needle size. A matrix, which allows the translation of the required number of tissue cores for different needle sizes, was generated. Results were compared to the true cumulative tissue weights of consecutively harvested tissue cores. The mean tissue weights obtained with the 11-G / 10-G Vacora® / 10-G Enspire® / 9-G / 8-G Original / 8-G Revolve™ / 7-G needles were 0.084 g / 0.142 g / 0.221 g / 0.121 g / 0.192 g / 0.334 g / 0.363 g, respectively. The calculated required numbers of VAB tissue cores for each needle size build the matrix. For example, the minimum calculated number of required cores according to the current German S3 guideline is 20 / 12 / 8 / 14 / 9 / 5 / 5 for needles of 11-G / 10-G Vacora® / 10-G Enspire® / 9-G / 8-G Original / 8-G Revolve™ / 7-G size. These numbers agree with the true cumulative tissue weights. The presented matrix facilitates the translation of the required number of VAB specimens between different needle sizes and thereby eases the implementation of current guidelines and consensus recommendations into clinical practice. © The Foundation Acta Radiologica 2014.

  3. KENNEDY SPACE CENTER, FLA. - Mobile Launcher Platform (MLP) number 3 and a set of twin solid rocket boosters, atop the crawler-transporter, crawl out of the Vehicle Assembly Building (VAB) in support of the second engineering analysis vibration test on the crawler and MLP. In the background is another MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB, travels toward Launch Pad 39A and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-21

    KENNEDY SPACE CENTER, FLA. - Mobile Launcher Platform (MLP) number 3 and a set of twin solid rocket boosters, atop the crawler-transporter, crawl out of the Vehicle Assembly Building (VAB) in support of the second engineering analysis vibration test on the crawler and MLP. In the background is another MLP. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB, travels toward Launch Pad 39A and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  4. KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. On either side of the boosters on the horizon can be seen the two launch pads. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-17

    KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. On either side of the boosters on the horizon can be seen the two launch pads. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  5. Investigation of a low NOx full-scale annular combustor

    NASA Technical Reports Server (NTRS)

    1982-01-01

    An atmospheric test program was conducted to evaluate a low NOx annular combustor concept suitable for a supersonic, high-altitude aircraft application. The lean premixed combustor, known as the vortex air blast (VAB) concept, was tested as a 22.0-cm diameter model in the early development phases to arrive at basic design and performance criteria. Final demonstration testing was carried out on a full scale combustor of 0.66-m diameter. Variable geometry dilution ports were incorporated to allow operation of the combustor across the range of conditions between idle (T(in) = 422 K, T(out) = 917 K) and cruise (T(in) = 833 K, T(out) - 1778 K). Test results show that the design could meet the program NOx goal of 1.0 g NO2/kg fuel at a one-atmospheric simulated cruise condition.

  6. KSC VAB Aeroacoustic Hazard Assessment

    NASA Technical Reports Server (NTRS)

    Oliveira, Justin M.; Yedo, Sabrina; Campbell, Michael D.; Atkinson, Joseph P.

    2010-01-01

    NASA Kennedy Space Center (KSC) carried out an analysis of the effects of aeroacoustics produced by stationary solid rocket motors in processing areas at KSC. In the current paper, attention is directed toward the acoustic effects of a motor burning within the Vehicle Assembly Building (VAB). The analysis was carried out with support from ASRC Aerospace who modeled transmission effects into surrounding facilities. Calculations were done using semi-analytical models for both aeroacoustics and transmission. From the results it was concluded that acoustic hazards in proximity to the source of ignition and plume can be severe; acoustic hazards in the far-field are significantly lower.

  7. Atlantis begins rolling back to the VAB

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Perched atop its Mobile Launcher Platform, Space Shuttle Atlantis moves back to the Vehicle Assembly Building, via the crawler- transporter underneath, along the crawlerway. The water in the background is part of the Banana River. Atlantis' return to the VAB was determined by Shuttle managers so that inspections, continuity checks and X-ray analysis can be conducted on the 36 solid rocket booster cables located inside each booster's system tunnel. An extensive evaluation of NASA's SRB cable inventory revealed conductor damage in four (of about 200) cables on the shelf. The launch has been rescheduled no earlier than Feb. 6.

  8. KSC-04pd0659

    NASA Image and Video Library

    2004-03-26

    CAPE CANAVERAL, Fla. -- This aerial photo shows the expanse of the Launch Complex 39 Area, bordered at the top by the Atlantic and a cloud-filled sky. At center right, towering above the surrounding sites, is the Vehicle Assembly Building. To the left is the Orbiter Processing Facility's Bay 3. In the foreground are OPF Bays 1 and 2. The two-lane crawlerway stretches from the VAB toward the coast, site of Launch Pad 39A, closest, and Launch Pad 39B, far left. Between the VAB and the ocean sprawl the Banana Creek and the Banana River. Photo credit: NASA

  9. KSC-03PD-3198

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis is moved into high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  10. KSC-03PD-3207

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis approaches the Vehicle Assembly Building (VAB) high bay 4. It is being towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  11. KSC-03PD-3193

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis is turned into position outside the Orbiter Processing Facility (OPF) for its tow to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  12. KSC-03PD-3195

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. Workers monitor the Space Shuttle orbiter Atlantis as it is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  13. KSC-03PD-3199

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. Workers back the Space Shuttle orbiter Atlantis out of the Orbiter Processing Facility (OPF) for its move to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  14. KSC-03PD-3200

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis is reflected in a rain puddle as it is towed from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  15. KSC-03PD-3203

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis is almost in position in high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  16. KSC-03PD-3201

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis approaches high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  17. KSC-03PD-3188

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis awaits a tow from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  18. KSC-03PD-3205

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis backs out of the Orbiter Processing Facility (OPF) for its move to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  19. KSC-03PD-3202

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis moves into high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  20. KSC-03PD-3191

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. Workers prepare to tow the Space Shuttle orbiter Atlantis from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  1. KSC-03PD-3204

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis arrives in high bay 4 of the Vehicle Assembly Building (VAB). It was towed from the Orbiter Processing Facility (OPF) to allow work to be performed in the bay that can only be accomplished while it is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  2. KSC-03PD-3206

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. Workers walk with Space Shuttle orbiter Atlantis from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB) high bay 4. The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to-flight mission, STS-114.

  3. KSC-03PD-3190

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Space Shuttle orbiter Atlantis is moments away from a tow from the Orbiter Processing Facility (OPF) to the Vehicle Assembly Building (VAB). The move will allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the processing facility includes annual validation of the bay's cranes, work platforms, lifting mechanisms, and jack stands. Atlantis will remain in the VAB for about 10 days, then return to the OPF as work resumes to prepare it for launch in September 2004 on the first return-to- flight mission, STS-114.

  4. KSC-2014-3266

    NASA Image and Video Library

    2014-07-23

    CAPE CANAVERAL, Fla. – Inside the Vehicle Assembly Building, or VAB, at NASA’s Kennedy Space Center in Florida, construction workers are hanging protective cloths around a work level near High Bay 3. Modifications are underway in the VAB to prepare High Bay 3 for a new platform system. The modifications are part of a centerwide refurbishment initiative under the Ground Systems Development and Operations Program. High bay 3 is being refurbished to accommodate NASA’s Space Launch System and a variety of other spacecraft. For more information, visit http://www.nasa.gov/exploration/systems/ground/index.html. Photo credit: NASA/Dimitri Gerondidakis

  5. KSC-2014-3265

    NASA Image and Video Library

    2014-07-23

    CAPE CANAVERAL, Fla. – Inside the Vehicle Assembly Building, or VAB, at NASA’s Kennedy Space Center in Florida, protective cloths are being placed around a work level near High Bay 3. Modifications are underway in the VAB to prepare High Bay 3 for a new platform system. The modifications are part of a centerwide refurbishment initiative under the Ground Systems Development and Operations Program. High bay 3 is being refurbished to accommodate NASA’s Space Launch System and a variety of other spacecraft. For more information, visit http://www.nasa.gov/exploration/systems/ground/index.html. Photo credit: NASA/Dimitri Gerondidakis

  6. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines nears the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be delivered to the VAB, where they will be stored and used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  7. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines backs up inside the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  8. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines backs in to the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  9. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines arrives inside the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  10. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    A flatbed truck carrying one of two new service platforms for NASA's Space Launch System booster engines arrives at the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  11. SLS Booster Engine Service Platforms Delivery

    NASA Image and Video Library

    2017-07-31

    One of two new work platforms for NASA's Space Launch System booster engines is secured on dunnage inside the Vehicle Assembly Building (VAB) at the agency's Kennedy Space Center in Florida. The platforms were transported from fabricator Met-Con Inc. in Cocoa, Florida. They will be stored in the VAB, where they will be used for processing and checkout of the engines for the rocket's twin five-segment solid rocket boosters for Exploration Mission-1. EM-1 will launch an uncrewed Orion spacecraft to a stable orbit beyond the Moon and bring it back to Earth for a splashdown in the Pacific Ocean.

  12. VAB Flag Painting

    NASA Image and Video Library

    2002-01-01

    On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the NASA logo on the southeast side of the Vehicle Assembly Building. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The U.S. flag is also being repainted. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary.

  13. Platform C South Arrival

    NASA Image and Video Library

    2016-08-05

    The second section of the first half of the C-level work platforms, C South, for NASA’s Space Launch System (SLS) rocket was offloaded from a heavy transport truck in a staging area on the west side of the Vehicle Assembly Building (VAB) at the agency’s Kennedy Space Center in Florida. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft and provide access for testing and processing.

  14. KSC-04PD-2023

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. On a scaffold barely visible along the south wall of the Vehicle Assembly Building near the NASA logo, workers are covering the holes with corrugated steel so the facility can be returned to performing operational activities. The VAB lost 820 panels from the south wall during the storm, and 25 additional panels pulled off the east wall by Hurricane Jeanne. Another scaffold is suspended near the top of the east wall (right side) for repairs. The VAB stands 525 feet tall. Central Florida, including Kennedy Space Center, has been battered by four hurricanes between Aug. 13 and Sept. 26.

  15. Investigating Autism-Related Symptoms in Children with Prader-Willi Syndrome: A Case Study

    PubMed Central

    Bennett, Jeffrey A.; Hodgetts, Sandra; Mackenzie, Michelle L.; Haqq, Andrea M.; Zwaigenbaum, Lonnie

    2017-01-01

    Prader-Willi syndrome (PWS), a rare genetic disorder caused by the lack of expression of paternal genes from chromosome 15q11-13, has been investigated for autism spectrum disorder (ASD) symptomatology in various studies. However, previous findings have been variable, and no studies investigating ASD symptomatology in PWS have exclusively studied children. We aimed to characterize social communication functioning and other ASD-related symptoms in children with PWS, and assessed agreement across measures and rates of ASD diagnosis. Measures included the Autism Diagnostic Observation Schedule-2 (ADOS-2), the Social Communication Questionnaire (SCQ), Social Responsiveness Scale-2 (SRS-2), Social Skills Improvement System-Rating Scales (SSIS-RS), and the Vineland Adaptive Behavioral Scales-II (VABS-II). General adaptive and intellectual skills were also assessed. Clinical best estimate (CBE) diagnosis was determined by an experienced developmental pediatrician, based on history and review of all available study measures, and taking into account overall developmental level. Participants included 10 children with PWS, aged 3 to 12 years. Three of the 10 children were male and genetic subtypes were two deletion (DEL) and eight uniparental disomy (UPD) (with a total of 6 female UPD cases). Although 8 of the 10 children exceeded cut-offs on at least one of the ASD assessments, agreement between parent questionnaires (SCQ, SRS-2, SSIS-RS) and observational assessment (ADOS-2) was very poor. None of the children were assigned a CBE diagnosis of ASD, with the caveat that the risk may have been lower because of the predominance of girls in the sample. The lack of agreement between the assessments emphasizes the complexity of interpreting ASD symptom measures in children with PWS. PMID:28264487

  16. Investigating Autism-Related Symptoms in Children with Prader-Willi Syndrome: A Case Study.

    PubMed

    Bennett, Jeffrey A; Hodgetts, Sandra; Mackenzie, Michelle L; Haqq, Andrea M; Zwaigenbaum, Lonnie

    2017-02-28

    Prader-Willi syndrome (PWS), a rare genetic disorder caused by the lack of expression of paternal genes from chromosome 15q11-13, has been investigated for autism spectrum disorder (ASD) symptomatology in various studies. However, previous findings have been variable, and no studies investigating ASD symptomatology in PWS have exclusively studied children. We aimed to characterize social communication functioning and other ASD-related symptoms in children with PWS, and assessed agreement across measures and rates of ASD diagnosis. Measures included the Autism Diagnostic Observation Schedule-2 (ADOS-2), the Social Communication Questionnaire (SCQ), Social Responsiveness Scale-2 (SRS-2), Social Skills Improvement System-Rating Scales (SSIS-RS), and the Vineland Adaptive Behavioral Scales-II (VABS-II). General adaptive and intellectual skills were also assessed. Clinical best estimate (CBE) diagnosis was determined by an experienced developmental pediatrician, based on history and review of all available study measures, and taking into account overall developmental level. Participants included 10 children with PWS, aged 3 to 12 years. Three of the 10 children were male and genetic subtypes were two deletion (DEL) and eight uniparental disomy (UPD) (with a total of 6 female UPD cases). Although 8 of the 10 children exceeded cut-offs on at least one of the ASD assessments, agreement between parent questionnaires (SCQ, SRS-2, SSIS-RS) and observational assessment (ADOS-2) was very poor. None of the children were assigned a CBE diagnosis of ASD, with the caveat that the risk may have been lower because of the predominance of girls in the sample. The lack of agreement between the assessments emphasizes the complexity of interpreting ASD symptom measures in children with PWS.

  17. KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. In the distance, at left, is Launch Pad 39A. The water on the right of the crawlerway is the Banana River. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-17

    KENNEDY SPACE CENTER, FLA. - The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. In the distance, at left, is Launch Pad 39A. The water on the right of the crawlerway is the Banana River. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  18. KENNEDY SPACE CENTER, FLA. - Viewed across the turn basin in the Launch Complex 39 Area, the crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB). The journey is in support of engineering analysis vibration tests on the crawler and MLP. The water on the right of the crawlerway is the Banana River. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

    NASA Image and Video Library

    2003-11-17

    KENNEDY SPACE CENTER, FLA. - Viewed across the turn basin in the Launch Complex 39 Area, the crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB). The journey is in support of engineering analysis vibration tests on the crawler and MLP. The water on the right of the crawlerway is the Banana River. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  19. Oral Health Characteristics of Preschool Children with Autistic Syndrome Disorder.

    PubMed

    Sarnat, Haim; Samuel, Eli; Ashkenazi-Alfasi, Naomi; Peretz, Benjamin

    2016-01-01

    to assess the dental status of young children with Autistic Syndrome Disorder (ASD) in order to allow better understanding of the dentist's role in treating these children. The ASD group consisted of 47 children diagnosed as ASD from three special kindergartens from three towns in Israel. The control group was 44 normally developed children from 4 kindergartens from 2 neighboring towns. Parents were asked to complete a questionnaire requesting the following: socio-demographic information, general medical condition, dental information (previous visit to a dentist, feeding habits, oral hygiene behavior, oral habits and the Vinland Adaptive Behavioral Scales (VABS). While in the control group there was no report of no brushing at all, among the ASD children 25% did not brush at all. Use of pacifier, fussy eating and eating problems were significantly more prevalent among the ASD group. In addition, the ASD children significantly preferred more salty, spicy and sweet foods than the control. There were more cariesfree children among the ASD group. In the ASD group, the ability to perform everyday life functions was slightly more than half of what is expected for age. autistic children have a relative age of one half, meaning they function at half the level of normally developed children at their chronological age, more eating problems and more persistent oral habits yet no correlation to dental health could be shown. Caries experience of autistic children was lower than in the control group, maintaining good oral hygiene is difficult for autistic children yet their gingival health was found to be good.

  20. The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses.

    PubMed

    Buxbaum, Joseph D; Bolshakova, Nadia; Brownfeld, Jessica M; Anney, Richard Jl; Bender, Patrick; Bernier, Raphael; Cook, Edwin H; Coon, Hilary; Cuccaro, Michael; Freitag, Christine M; Hallmayer, Joachim; Geschwind, Daniel; Klauck, Sabine M; Nurnberger, John I; Oliveira, Guiomar; Pinto, Dalila; Poustka, Fritz; Scherer, Stephen W; Shih, Andy; Sutcliffe, James S; Szatmari, Peter; Vicente, Astrid M; Vieland, Veronica; Gallagher, Louise

    2014-01-01

    There is an urgent need for expanding and enhancing autism spectrum disorder (ASD) samples, in order to better understand causes of ASD. In a unique public-private partnership, 13 sites with extensive experience in both the assessment and diagnosis of ASD embarked on an ambitious, 2-year program to collect samples for genetic and phenotypic research and begin analyses on these samples. The program was called The Autism Simplex Collection (TASC). TASC sample collection began in 2008 and was completed in 2010, and included nine sites from North America and four sites from Western Europe, as well as a centralized Data Coordinating Center. Over 1,700 trios are part of this collection, with DNA from transformed cells now available through the National Institute of Mental Health (NIMH). Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule-Generic (ADOS-G) measures are available for all probands, as are standardized IQ measures, Vineland Adaptive Behavioral Scales (VABS), the Social Responsiveness Scale (SRS), Peabody Picture Vocabulary Test (PPVT), and physical measures (height, weight, and head circumference). At almost every site, additional phenotypic measures were collected, including the Broad Autism Phenotype Questionnaire (BAPQ) and Repetitive Behavior Scale-Revised (RBS-R), as well as the non-word repetition scale, Communication Checklist (Children's or Adult), and Aberrant Behavior Checklist (ABC). Moreover, for nearly 1,000 trios, the Autism Genome Project Consortium (AGP) has carried out Illumina 1 M SNP genotyping and called copy number variation (CNV) in the samples, with data being made available through the National Institutes of Health (NIH). Whole exome sequencing (WES) has been carried out in over 500 probands, together with ancestry matched controls, and this data is also available through the NIH. Additional WES is being carried out by the Autism Sequencing Consortium (ASC), where the focus is on sequencing complete trios. ASC sequencing for the first 1,000 samples (all from whole-blood DNA) is complete and data will be released in 2014. Data is being made available through NIH databases (database of Genotypes and Phenotypes (dbGaP) and National Database for Autism Research (NDAR)) with DNA released in Dist 11.0. Primary funding for the collection, genotyping, sequencing and distribution of TASC samples was provided by Autism Speaks and the NIH, including the National Institute of Mental Health (NIMH) and the National Human Genetics Research Institute (NHGRI). TASC represents an important sample set that leverages expert sites. Similar approaches, leveraging expert sites and ongoing studies, represent an important path towards further enhancing available ASD samples.

  1. KSC-98pc1166

    NASA Image and Video Library

    1998-09-28

    The orbiter Atlantis, being towed from the Shuttle Landing Facility toward the Vehicle Assembly Building (VAB) , intersects the morning sun's rays. In the background, to the right of the VAB, are the Orbiter Processing Facility 1 and 2. Atlantis spent 10 months in Palmdale, CA, undergoing extensive inspections and modifications in the orbiter processing facility there. The modifications included several upgrades enabling it to support International Space Station missions, such as adding an external airlock for ISS docking missions and installing thinner, lighter thermal protection blankets for weight reduction which will allow it to haul heavier cargo. Atlantis will undergo preparations at KSC in Orbiter Processing Facility 2 for its planned flight in June 1999

  2. Platform C North Arrival

    NASA Image and Video Library

    2016-08-30

    A section of the second half of the C-level platforms, C North, for NASA’s Space Launch System (SLS) rocket, arrives at the agency’s Kennedy Space Center in Florida. The platform was offloaded from a heavy lift transport truck and secured in a staging area in the west parking lot of the Vehicle Assembly Building (VAB). The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft and provide access for testing and processing.

  3. KSC-2012-1083

    NASA Image and Video Library

    2012-01-20

    CAPE CANAVERAL, Fla. -- Protective plastic flanks the nose of space shuttle Atlantis for its move from Orbiter Processing Facility-2 to the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. Atlantis will be stored temporarily in the VAB while transition and retirement processing resumes on shuttle Endeavour in the processing hangar. Endeavour is being prepared for public display at the California Science Center in Los Angeles. A groundbreaking was held Jan. 18 for Atlantis' future home -- a 65,000-square-foot exhibit in Shuttle Plaza at the Kennedy Space Center Visitor Complex. For additional information, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jim Grossmann

  4. An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegans.

    PubMed

    Miller, Michael A; Ruest, Paul J; Kosinski, Mary; Hanks, Steven K; Greenstein, David

    2003-01-15

    During sexual reproduction in most animals, oocytes arrest in meiotic prophase and resume meiosis (meiotic maturation) in response to sperm or somatic cell signals. Despite progress in delineating mitogen-activated protein kinase (MAPK) and CDK/cyclin activation pathways involved in meiotic maturation, it is less clear how these pathways are regulated at the cell surface. The Caenorhabditis elegans major sperm protein (MSP) signals oocytes, which are arrested in meiotic prophase, to resume meiosis and ovulate. We used DNA microarray data and an in situ binding assay to identify the VAB-1 Eph receptor protein-tyrosine kinase as an MSP receptor. We show that VAB-1 and a somatic gonadal sheath cell-dependent pathway, defined by the CEH-18 POU-class homeoprotein, negatively regulate meiotic maturation and MAPK activation. MSP antagonizes these inhibitory signaling circuits, in part by binding VAB-1 on oocytes and sheath cells. Our results define a sperm-sensing control mechanism that inhibits oocyte maturation, MAPK activation, and ovulation when sperm are unavailable for fertilization. MSP-domain proteins are found in diverse animal taxa, where they may regulate contact-dependent Eph receptor signaling pathways.

  5. Parallel Quantum Circuit in a Tunnel Junction

    NASA Astrophysics Data System (ADS)

    Faizy Namarvar, Omid; Dridi, Ghassen; Joachim, Christian

    2016-07-01

    Spectral analysis of 1 and 2-states per line quantum bus are normally sufficient to determine the effective Vab(N) electronic coupling between the emitter and receiver states through the bus as a function of the number N of parallel lines. When Vab(N) is difficult to determine, an Heisenberg-Rabi time dependent quantum exchange process must be triggered through the bus to capture the secular oscillation frequency Ωab(N) between those states. Two different linear and regimes are demonstrated for Ωab(N) as a function of N. When the initial preparation is replaced by coupling of the quantum bus to semi-infinite electrodes, the resulting quantum transduction process is not faithfully following the Ωab(N) variations. Because of the electronic transparency normalisation to unity and of the low pass filter character of this transduction, large Ωab(N) cannot be captured by the tunnel junction. The broadly used concept of electrical contact between a metallic nanopad and a molecular device must be better described as a quantum transduction process. At small coupling and when N is small enough not to compensate for this small coupling, an N2 power law is preserved for Ωab(N) and for Vab(N).

  6. Parallel Quantum Circuit in a Tunnel Junction

    PubMed Central

    Faizy Namarvar, Omid; Dridi, Ghassen; Joachim, Christian

    2016-01-01

    Spectral analysis of 1 and 2-states per line quantum bus are normally sufficient to determine the effective Vab(N) electronic coupling between the emitter and receiver states through the bus as a function of the number N of parallel lines. When Vab(N) is difficult to determine, an Heisenberg-Rabi time dependent quantum exchange process must be triggered through the bus to capture the secular oscillation frequency Ωab(N) between those states. Two different linear and regimes are demonstrated for Ωab(N) as a function of N. When the initial preparation is replaced by coupling of the quantum bus to semi-infinite electrodes, the resulting quantum transduction process is not faithfully following the Ωab(N) variations. Because of the electronic transparency normalisation to unity and of the low pass filter character of this transduction, large Ωab(N) cannot be captured by the tunnel junction. The broadly used concept of electrical contact between a metallic nanopad and a molecular device must be better described as a quantum transduction process. At small coupling and when N is small enough not to compensate for this small coupling, an N2 power law is preserved for Ωab(N) and for Vab(N). PMID:27453262

  7. Parallel Quantum Circuit in a Tunnel Junction.

    PubMed

    Faizy Namarvar, Omid; Dridi, Ghassen; Joachim, Christian

    2016-07-25

    Spectral analysis of 1 and 2-states per line quantum bus are normally sufficient to determine the effective Vab(N) electronic coupling between the emitter and receiver states through the bus as a function of the number N of parallel lines. When Vab(N) is difficult to determine, an Heisenberg-Rabi time dependent quantum exchange process must be triggered through the bus to capture the secular oscillation frequency Ωab(N) between those states. Two different linear and regimes are demonstrated for Ωab(N) as a function of N. When the initial preparation is replaced by coupling of the quantum bus to semi-infinite electrodes, the resulting quantum transduction process is not faithfully following the Ωab(N) variations. Because of the electronic transparency normalisation to unity and of the low pass filter character of this transduction, large Ωab(N) cannot be captured by the tunnel junction. The broadly used concept of electrical contact between a metallic nanopad and a molecular device must be better described as a quantum transduction process. At small coupling and when N is small enough not to compensate for this small coupling, an N(2) power law is preserved for Ωab(N) and for Vab(N).

  8. First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions).

    PubMed

    Rageth, Christoph J; O'Flynn, Elizabeth Am; Comstock, Christopher; Kurtz, Claudia; Kubik, Rahel; Madjar, Helmut; Lepori, Domenico; Kampmann, Gert; Mundinger, Alexander; Baege, Astrid; Decker, Thomas; Hosch, Stefanie; Tausch, Christoph; Delaloye, Jean-François; Morris, Elisabeth; Varga, Zsuzsanna

    2016-09-01

    The purpose of this study is to obtain a consensus for the therapy of B3 lesions. The first International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions) including atypical ductal hyperplasia (ADH), flat epithelial atypia (FEA), classical lobular neoplasia (LN), papillary lesions (PL), benign phyllodes tumors (PT), and radial scars (RS) took place in January 2016 in Zurich, Switzerland organized by the International Breast Ultrasound School and the Swiss Minimally Invasive Breast Biopsy group-a subgroup of the Swiss Society of Senology. Consensus recommendations for the management and follow-up surveillance of these B3 lesions were developed and areas of research priorities were identified. The consensus recommendation for FEA, LN, PL, and RS diagnosed on core needle biopsy or vacuum-assisted biopsy (VAB) is to therapeutically excise the lesion seen on imaging by VAB and no longer by open surgery, with follow-up surveillance imaging for 5 years. The consensus recommendation for ADH and PT is, with some exceptions, therapeutic first-line open surgical excision. Minimally invasive management of selected B3 lesions with therapeutic VAB is acceptable as an alternative to first-line surgical excision.

  9. Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders

    PubMed Central

    Walker, Cheryl K.; Bremer, Andrew A.; Baker, Alice S.; Ozonoff, Sally; Hansen, Robin L.; Hertz-Picciotto, Irva

    2012-01-01

    OBJECTIVE: We examined whether metabolic conditions (MCs) during pregnancy (diabetes, hypertension, and obesity) are associated with autism spectrum disorder (ASD), developmental delays (DD), or impairments in specific domains of development in the offspring. METHODS: Children aged 2 to 5 years (517 ASD, 172 DD, and 315 controls) were enrolled in the CHARGE (Childhood Autism Risks from Genetics and the Environment) study, a population-based, case-control investigation between January 2003 and June 2010. Eligible children were born in California, had parents who spoke English or Spanish, and were living with a biological parent in selected regions of California. Children’s diagnoses were confirmed by using standardized assessments. Information regarding maternal conditions was ascertained from medical records or structured interview with the mother. RESULTS: All MCs were more prevalent among case mothers compared with controls. Collectively, these conditions were associated with a higher likelihood of ASD and DD relative to controls (odds ratio: 1.61 [95% confidence interval: 1.10–2.37; odds ratio: 2.35 [95% confidence interval: 1.43–3.88], respectively). Among ASD cases, children of women with diabetes had Mullen Scales of Early Learning (MSEL) expressive language scores 0.4 SD lower than children of mothers without MCs (P < .01). Among children without ASD, those exposed to any MC scored lower on all MSEL and Vineland Adaptive Behavior Scales (VABS) subscales and composites by at least 0.4 SD (P < .01 for each subscale/composite). CONCLUSIONS: Maternal MCs may be broadly associated with neurodevelopmental problems in children. With obesity rising steadily, these results appear to raise serious public health concerns. PMID:22492772

  10. KSC-2009-5823

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – External tank 134 is towed toward the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Pegasus barge, carrying the fuel tank, arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. Next, the tank will be transported into the VAB where it will be stored until needed. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  11. KSC-2009-5822

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – External tank 134 emerges from the Pegasus barge docked in the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. The fuel tank next will be transported into the VAB where it will be stored until needed. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  12. KSC-2011-4047

    NASA Image and Video Library

    2011-05-25

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, an adult osprey guards its young in a nest built on a platform in the Press Site parking lot. In the background is the 12,300-square-foot NASA logo painted on the side of the Vehicle Assembly Building (VAB). The VAB and Press Site are located at the Turn Basin in Launch Complex 39, making it an ideal osprey nesting place. The Merritt Island National Wildlife Refuge overlaps with Kennedy Space Center property and provides a habitat for many types of wildlife, including the osprey, and 330 species of birds. For information on the refuge, visit http://www.fws.gov/merrittisland/Index.html. Photo credit: NASA/Jack Pfaller

  13. KSC-98pc373

    NASA Image and Video Library

    1998-03-16

    KENNEDY SPACE CENTER, FLA. -- The Space Shuttle orbiter Columbia was transferred from Orbiter Processing Facility Bay 3 today to the Vehicle Assembly Building (VAB), where it will be mated to its external tank and solid rocket boosters. Here it is shown in the transfer aisle of the VAB. Columbia is being prepared for the STS-90 mission, carrying the Neurolab payload. Investigations during the Neurolab mission will focus on the effects of microgravity on the nervous system. The mission is a joint venture of six space agencies and seven U.S. research agencies. Investigator teams from nine countries will conduct 31 studies in the microgravity environment of space. The launch is targeted for April 16 at 2:19 p.m. EDT

  14. KSC-98pc372

    NASA Image and Video Library

    1998-03-16

    KENNEDY SPACE CENTER, FLA. -- The Space Shuttle orbiter Columbia was transferred from Orbiter Processing Facility Bay 3 today to the Vehicle Assembly Building (VAB), where it will be mated to its external tank and solid rocket boosters. Here it is shown on its way to the VAB. Columbia is being prepared for the STS-90 mission, carrying the Neurolab payload. Investigations during the Neurolab mission will focus on the effects of microgravity on the nervous system. The mission is a joint venture of six space agencies and seven U.S. research agencies. Investigator teams from nine countries will conduct 31 studies in the microgravity environment of space. The launch is targeted for April 16 at 2:19 p.m. EDT

  15. KSC-2011-3051

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is positioned between the twin solid rocket boosters on the mobile launcher platform in high bay-1. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  16. KSC-2011-3053

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is positioned between the twin solid rocket boosters on the mobile launcher platform in high bay-1. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  17. KSC-2011-3049

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is being lowered between the twin solid rocket boosters on the mobile launcher platform in high bay-1. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  18. Workers painting the Flag and Meatball on the VAB

    NASA Image and Video Library

    2007-01-03

    Elevated platforms are seen hanging on the side of Kennedy Space Center's Vehicle Assembly Building in a view looking across from the turn basin. To the right is the large external tank barge. Workers, suspended on the platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet.

  19. Platform C Installation

    NASA Image and Video Library

    2016-10-19

    A heavy-lift crane lifts the first half of the C-level work platforms, C south, for NASA’s Space Launch System (SLS) rocket, high up from the transfer aisle floor of the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. The C platform will be installed on the south side of High Bay 3. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  20. Platform C North Installation

    NASA Image and Video Library

    2016-11-10

    A heavy-lift crane lifts the second half of the C-level work platforms, C north, for NASA’s Space Launch System (SLS) rocket, high up from the transfer aisle floor of the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. The C platform will be installed on the north side of High Bay 3. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  1. Platform C Installation

    NASA Image and Video Library

    2016-10-19

    A heavy-lift crane lifts the first half of the C-level work platforms, C south, for NASA’s Space Launch System (SLS) rocket, high up from the transfer aisle floor of the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. The C platform will be moved into High Bay 3 for installation on the south wall. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  2. Platform C North Installation

    NASA Image and Video Library

    2016-11-10

    A heavy-lift crane lifts the second half of the C-level work platforms, C north, for NASA’s Space Launch System (SLS) rocket, up from the transfer aisle floor of the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. The C platform will be installed on the north side of High Bay 3. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  3. Platform C Installation

    NASA Image and Video Library

    2016-10-19

    A heavy-lift crane lowers the first half of the C-level work platforms, C south, for NASA’s Space Launch System (SLS) rocket, for installation on the south side of High Bay 3 in the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. In view below Platform C are several of the previously installed platforms. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  4. Platform C North Installation

    NASA Image and Video Library

    2016-11-10

    A heavy-lift crane lifts the second half of the C-level work platforms, C north, for NASA’s Space Launch System (SLS) rocket, high up from the transfer aisle floor of the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. The C platform will be moved into High Bay 3 for installation on the north wall. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  5. KSC-2014-3264

    NASA Image and Video Library

    2014-07-23

    CAPE CANAVERAL, Fla. – Steel structures surround High Bay 3 inside the Vehicle Assembly Building, or VAB, at NASA’s Kennedy Space Center in Florida. In view, high above, is the 175-ton crane. Banners note the heights of the Saturn V, Space Launch System, or SLS, and shuttle on the steel structure. Modifications are underway in the VAB to prepare High Bay 3 for a new platform system. The modifications are part of a centerwide refurbishment initiative under the Ground Systems Development and Operations Program. High bay 3 is being refurbished to accommodate NASA’s Space Launch System and a variety of other spacecraft. For more information, visit http://www.nasa.gov/exploration/systems/ground/index.html. Photo credit: NASA/Dimitri Gerondidakis

  6. Adaptive behaviour in children and adolescents with foetal alcohol spectrum disorders: a comparison with specific learning disability and typical development

    PubMed Central

    Autti-Rämö, Ilona; Kalland, Mirjam; Santtila, Pekka; Hoyme, H. Eugene; Mattson, Sarah N.; Korkman, Marit

    2013-01-01

    Foetal alcohol spectrum disorders (FASD) is a leading cause of intellectual disability in the western world. Children and adolescents with FASD are often exposed to a double burden in life, as their neurological sequelae are accompanied by adverse living surroundings exposing them to further environmental risk. In the present study, the adaptive abilities of a group of children and adolescents with FASD were examined using the Vineland Adaptive Behaviour Scales (VABS) and compared to those of a group of IQ-matched children with specific learning disorder (SLD) as well as with typically developing controls (CON). The results showed significantly different adaptive abilities among the groups: Children with FASD performed worse than IQ-matched children with SLD, who in turn performed worse than typically developing children on all domains (communication, daily living skills and socialization) on the VABS. Compared to the other groups, social skills declined with age in the FASD group. These results support previous studies of adaptive behaviour deficits in children with FASD and provide further evidence of the specificity of these deficits. On a societal level, more efforts and resources should be focused on recognizing and diagnosing FASD and supporting communication skills, daily living skills and most of all social skills across diagnostic groups within FASD. Without adequate intervention, adolescents and young adults with FASD run a great risk of marginalization and social maladjustment, costly not only to society but also to the lives of the many young people with FASD. PMID:22358422

  7. Predictors of parenting stress in mothers of children with spina bifida.

    PubMed

    Kanaheswari, Y; Razak, N N A; Chandran, V; Ong, L C

    2011-03-01

    Prospective cross-sectional multidimensional study using clinical assessment and standard measures. To determine the medical and social factors associated with parenting stress among mothers of children with spina bifida. Spina bifida clinics of two tertiary hospitals in urban Kuala Lumpur, Malaysia. A total of 81 mothers of children aged 1-18 years completed the Parenting Stress Index-Short Form (PSI/SF). Each child's adaptive skills were assessed using the Vineland Adaptive Behaviour Scales (VABS), Interview Edition. Medical and social data were obtained from direct interviews and case note reviews. Hierarchical multiple regression analysis was used to investigate factors that were determinants for high scores in the parental distress (PD), difficult child (DC) and parent-child dysfunctional interaction (P-CDI) subdomains of the PSI/SF. Results were expressed as beta coefficient (β) and 95% confidence intervals (95% CIs). Single-parent families (β 8.6, 95% CI 3.4-13.9) and the need for clean intermittent catheterization of bladder (β 3.5, 95% CI 0.7-6.2) were associated with high PD scores. Clean intermittent catheterization (β 3.0, 95% CI 0.5-5.5) was associated with higher DC scores. Lower composite VABS scores (β -0.08, 95% CI -0.02 to -0.15) and mother as the sole caregiver (β 2.6, 95% CI 0.15-4.96) was associated with higher P-CDI scores. The need for clean intermittent catheterization was the only medical factor associated with parenting stress in mothers of children with spina bifida. This was mediated by single parenthood, caregiver status and the child's adaptive skills.

  8. KSC-04PD-1808

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. KSC videographer Glenn Benson and photographer Kenny Allen photograph damage incurred on the south wall of the Vehicle Assembly Building (VAB) that sustained damage from Hurricane Frances as it passed over Central Florida during the Labor Day weekend. The maximum wind at the surface from Hurricane Frances was 94 mph from the northeast at 6:40 a.m. on Sunday, September 5. It was recorded at a weather tower located on the east shore of the Mosquito Lagoon near the Cape Canaveral National Seashore. The highest sustained wind at KSC was 68 mph. The VAB lost 820, 4- x 16-foot panels or more than 52,000 square feet of its surface. There was damage to the roof as well.

  9. KSC-04pd1807

    NASA Image and Video Library

    2004-09-14

    KENNEDY SPACE CENTER, FLA. - KSC videographer Glenn Benson adjusts a high definition camera being used to photograph the south wall of the Vehicle Assembly Building (VAB) that sustained damage from Hurricane Frances as it passed over Central Florida during the Labor Day weekend. The maximum wind at the surface from Hurricane Frances was 94 mph from the northeast at 6:40 a.m. on Sunday, September 5. It was recorded at a weather tower located on the east shore of the Mosquito Lagoon near the Cape Canaveral National Seashore. The highest sustained wind at KSC was 68 mph. The VAB lost 820, 4- x 16-foot panels or more than 52,000 square feet of its surface. There was damage to the roof as well.

  10. KSC-04pd1808

    NASA Image and Video Library

    2004-09-14

    KENNEDY SPACE CENTER, FLA. - KSC videographer Glenn Benson and photographer Kenny Allen photograph damage incurred on the south wall of the Vehicle Assembly Building (VAB) that sustained damage from Hurricane Frances as it passed over Central Florida during the Labor Day weekend. The maximum wind at the surface from Hurricane Frances was 94 mph from the northeast at 6:40 a.m. on Sunday, September 5. It was recorded at a weather tower located on the east shore of the Mosquito Lagoon near the Cape Canaveral National Seashore. The highest sustained wind at KSC was 68 mph. The VAB lost 820, 4- x 16-foot panels or more than 52,000 square feet of its surface. There was damage to the roof as well.

  11. KSC-04PD-1807

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. KSC videographer Glenn Benson adjusts a high definition camera being used to photograph the south wall of the Vehicle Assembly Building (VAB) that sustained damage from Hurricane Frances as it passed over Central Florida during the Labor Day weekend. The maximum wind at the surface from Hurricane Frances was 94 mph from the northeast at 6:40 a.m. on Sunday, September 5. It was recorded at a weather tower located on the east shore of the Mosquito Lagoon near the Cape Canaveral National Seashore. The highest sustained wind at KSC was 68 mph. The VAB lost 820, 4- x 16-foot panels or more than 52,000 square feet of its surface. There was damage to the roof as well.

  12. KSC-2009-5810

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – NASA's Liberty Star, one of NASA's a solid rocket booster retrieval ships, moves through the locks at Port Canaveral. The ship towed the Pegasus barge, carrying external tank 134, from NASA's Michoud Assembly Facility near New Orleans. A tugboat will bring the barge through the Banana River to its destination in the turn basin near Kennedy Space Center's Vehicle Assembly Building, or VAB, where the tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  13. KSC-2009-5819

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – Tugboats safely deliver the Pegasus barge, carrying external tank 134, to the dock in the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  14. KSC-2009-5818

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – Tugboats safely deliver the Pegasus barge, carrying external tank 134, to the dock in the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  15. KSC-2009-5825

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – External tank 134 is towed toward the open door of the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Pegasus barge, carrying the fuel tank, arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. Next, the tank will be transported into the VAB where it will be stored until needed. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  16. KSC-2009-5821

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – A worker tows external tank 134 off the Pegasus barge docked in the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After the fuel tank is offloaded, it will be transported into the VAB where it will be stored until needed. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  17. KSC-2009-5817

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – Tugboats safely deliver the Pegasus barge, carrying external tank 134, to the dock in the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  18. KSC-2009-5820

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – Workers prepare to offload external tank 134 from the Pegasus barge docked in the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  19. KSC-2009-5824

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – External tank 134 is towed toward the looming 525-foot-tall Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Pegasus barge, carrying the fuel tank, arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. Next, the tank will be transported into the VAB where it will be stored until needed. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  20. KSC-2011-1797

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, media photograph space shuttle Endeavour's move, or "rollover," to the Vehicle Assembly Building (VAB) from Orbiter Processing Facility-2. In the VAB, Endeavour will be lifted into a high bay where it will be attached to its external fuel tank and solid rocket boosters for its final and upcoming STS-134 mission. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, spare parts, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA

  1. KSC-2011-1902

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Endeavour approaches the Vehicle Assembly Building, or VAB, on its move from Orbiter Processing Facility-2 where it was processed for its final mission, STS-134. In the VAB, Endeavour will be lifted into a high bay where it will be joined to its external fuel tank and solid rocket boosters. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA/Jack Pfaller

  2. KSC-2011-1903

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Endeavour approaches the Vehicle Assembly Building, or VAB, on its move from Orbiter Processing Facility-2 where it was processed for its final mission, STS-134. In the VAB, Endeavour will be lifted into a high bay where it will be joined to its external fuel tank and solid rocket boosters. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA/Jack Pfaller

  3. KSC-08pd3895

    NASA Image and Video Library

    2008-12-03

    CAPE CANAVERAL, Fla. -- An alligator basks in the sun on the bank of the Banana River near NASA's Kennedy Space Center in Florida. It is witness to the passage of the Pegasus barge through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus, carrying external tank 130, arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After the Pegasus docks, the fuel tank will be offloaded and transported to the VAB. External tank 130 is the one designated for space shuttle Endeavour on the STS-127 mission targeted for launch on May 15. Photo credit: NASA/Troy Cryder

  4. KSC-08pd3896

    NASA Image and Video Library

    2008-12-03

    CAPE CANAVERAL, Fla. -- An alligator basks in the sun on the bank of the Banana River near NASA's Kennedy Space Center in Florida. It is witness to the passage of the Pegasus barge through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus, carrying external tank 130, arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After the Pegasus docks, the fuel tank will be offloaded and transported to the VAB. External tank 130 is the one designated for space shuttle Endeavour on the STS-127 mission targeted for launch on May 15. Photo credit: NASA/Troy Cryder

  5. KSC-2011-3035

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank for space shuttle Atlantis' STS-135 mission, ET-138, is prepared for transfer from its test cell to high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  6. KSC-2011-3043

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is lowered into high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  7. KSC-2011-3038

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is lifted from its test cell for transfer to high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  8. KSC-2011-3050

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers monitor the progress of external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, as it is lowered into high bay-1 between the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  9. KSC-2011-3045

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers monitor the progress of external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, as it is lowered into high bay-1 between the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  10. KSC-2011-3041

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is lowered into high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  11. KSC-2011-3044

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is lowered into high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  12. KSC-2011-3040

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is transferred to high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  13. KSC-2011-3034

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank for space shuttle Atlantis' STS-135 mission, ET-138, is prepared for transfer from its test cell to high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  14. KSC-2011-3052

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers monitor the progress of external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, as it is positioned between the twin solid rocket boosters on the mobile launcher platform in high bay-1. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  15. KSC-2011-3046

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers monitor the progress of external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, as it is lowered into high bay-1 between the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  16. KSC-2011-3042

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is lowered into high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  17. KSC-2011-3037

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is lifted from its test cell for transfer to high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  18. KSC-2011-3039

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, is transferred to high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  19. KSC-2011-3048

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers guide external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, as it is lowered into high bay-1 between the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  20. KSC-2011-3047

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers guide external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, as it is lowered into high bay-1 between the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  1. Workers painting the Flag and Meatball on the VAB

    NASA Image and Video Library

    2007-01-03

    Elevated platforms are seen hanging in front of the NASA Logo on the side of Kennedy Space Center's Vehicle Assembly Building. Also in view on the east side of the building are platforms on the facility's large vertical doors. Workers, suspended on the platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet.

  2. Platform B North Installation

    NASA Image and Video Library

    2016-12-16

    Construction workers wearing safety harnesses and tethered lines assist with the installation of the second half of the B-level work platforms, B north, for NASA’s Space Launch System (SLS) rocket, high up in the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. They are securing the large bolts that hold the platform securely in place on the north side of High Bay 3. The B platforms are the ninth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  3. Platform C North Installation

    NASA Image and Video Library

    2016-11-10

    A heavy-lift crane lifts the second half of the C-level work platforms, C north, for NASA’s Space Launch System (SLS) rocket, high up from the transfer aisle of the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The C platform will be moved into High Bay 3 for installation on the north side of High Bay 3. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  4. Platform C North Installation

    NASA Image and Video Library

    2016-11-10

    A heavy-lift crane lowers the second half of the C-level work platforms, C north, for NASA’s Space Launch System (SLS) rocket, into High Bay 3 of the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The C platform will be installed on the north side of High Bay 3. In view below are several of the previously installed levels of platforms. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  5. Platform B North Installation

    NASA Image and Video Library

    2016-12-16

    A construction worker solders a section of steel during the installation of the second half of the B-level work platforms, B north, for NASA's Space Launch System (SLS) rocket, in High Bay 3 in the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. Construction workers will secure the large bolts that hold the platform in place on the north wall. The B platforms are the ninth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  6. Artistic view of VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    A bundle of flexible pipes arcing toward the Vehicle Assembly Building (left) and Operations Support Building (right) presents an artistic design to travelers on nearby Kennedy Parkway and Saturn Causeway.

  7. The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses

    PubMed Central

    2014-01-01

    Background There is an urgent need for expanding and enhancing autism spectrum disorder (ASD) samples, in order to better understand causes of ASD. Methods In a unique public-private partnership, 13 sites with extensive experience in both the assessment and diagnosis of ASD embarked on an ambitious, 2-year program to collect samples for genetic and phenotypic research and begin analyses on these samples. The program was called The Autism Simplex Collection (TASC). TASC sample collection began in 2008 and was completed in 2010, and included nine sites from North America and four sites from Western Europe, as well as a centralized Data Coordinating Center. Results Over 1,700 trios are part of this collection, with DNA from transformed cells now available through the National Institute of Mental Health (NIMH). Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule-Generic (ADOS-G) measures are available for all probands, as are standardized IQ measures, Vineland Adaptive Behavioral Scales (VABS), the Social Responsiveness Scale (SRS), Peabody Picture Vocabulary Test (PPVT), and physical measures (height, weight, and head circumference). At almost every site, additional phenotypic measures were collected, including the Broad Autism Phenotype Questionnaire (BAPQ) and Repetitive Behavior Scale-Revised (RBS-R), as well as the non-word repetition scale, Communication Checklist (Children’s or Adult), and Aberrant Behavior Checklist (ABC). Moreover, for nearly 1,000 trios, the Autism Genome Project Consortium (AGP) has carried out Illumina 1 M SNP genotyping and called copy number variation (CNV) in the samples, with data being made available through the National Institutes of Health (NIH). Whole exome sequencing (WES) has been carried out in over 500 probands, together with ancestry matched controls, and this data is also available through the NIH. Additional WES is being carried out by the Autism Sequencing Consortium (ASC), where the focus is on sequencing complete trios. ASC sequencing for the first 1,000 samples (all from whole-blood DNA) is complete and data will be released in 2014. Data is being made available through NIH databases (database of Genotypes and Phenotypes (dbGaP) and National Database for Autism Research (NDAR)) with DNA released in Dist 11.0. Primary funding for the collection, genotyping, sequencing and distribution of TASC samples was provided by Autism Speaks and the NIH, including the National Institute of Mental Health (NIMH) and the National Human Genetics Research Institute (NHGRI). Conclusions TASC represents an important sample set that leverages expert sites. Similar approaches, leveraging expert sites and ongoing studies, represent an important path towards further enhancing available ASD samples. PMID:25392729

  8. Transcutaneous bilirubinometry reduces the need for blood sampling in neonates with visible jaundice.

    PubMed

    Mishra, S; Chawla, D; Agarwal, R; Deorari, A K; Paul, V K; Bhutani, V K

    2009-12-01

    We determined usefulness of transcutaneous bilirubinometry to decrease the need for blood sampling to assay serum total bilirubin (STB) in the management of jaundiced healthy Indian neonates. Newborns, > or =35 weeks' gestation, with clinical evidence of jaundice were enrolled in an institutional approved randomized clinical trial. The severity of hyperbilirubinaemia was determined by two non-invasive methods: i) protocol-based visual assessment of bilirubin (VaB) and ii) transcutaneous bilirubin (TcB) determination (BiliCheck). By a random allocation, either method was used to decide the need for blood sampling, which was defined to be present if assessed STB by allocated method exceeded 80% of hour-specific threshold values for phototherapy (2004 AAP Guidelines). A total of 617 neonates were randomized to either TcB (n = 314) or VaB (n = 303) groups with comparable gestation, birth weight and postnatal age. Need for blood sampling to assay STB was 34% lower (95% CI: 10% to 51%) in the TcB group compared with VaB group (17.5% vs 26.4% assessments; risk difference: -8.9%, 95% CI: -2.4% to -15.4%; p = 0.008). Routine use of transcutaneous bilirubinometry compared with systematic visual assessment of bilirubin significantly reduced the need for blood sampling to assay STB in jaundiced term and late-preterm neonates. (ClinicalTrials.gov number, NCT00653874).

  9. [Observational medicine in 19th century Iran].

    PubMed

    Ebrahimnejad, H

    1998-01-01

    The ravages wrought by epidemics in Iran as of 1821 acted as a stimulus to medical thought while the awakening of political consciousness mobilized efforts to fight contagious diseases. The combination "epidemics-politics-medicine" made nineteenth-century Persia turn to European science for help. Thus western medicine was introduced into Persia. If this introduction has been perceived by political means and epidemiological justification, the theoretical and epistemological process involved has been almost completely overlooked or misinterpreted. It is generally considered that the imported medicine swept away the local one, but this is not altogether true. It was the internal evolution of traditional medicine which paved the way for anatomoclinical medicine. This evolution comes accross clearly in the works of Shirâzi and Sâveji between 1831 and 1862, years in which epidemics struck frequently and violently. While Europeans in Iran such as Dr. Polak qualified heyzeh (a kind of severe diarrhea) a "sporadic cholera" or "autumn cholera", Shirâzi wrote three treatises to show that heyzeh was not cholera but an ordinary kind of diarrhea caused by generalized malnourishment. Shirâzi was also an innovator in the theoretical and terminological fields, doing away with the notion of vabâ which meant a putrid atmosphere. Vabâ became a physiological anomaly which took on epidemic proportions in an impure atmosphere. The modern definition of vabâ meaning cholera was therefore elaborated thanks to Shirâzi.

  10. KSC-2010-4908

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- This overhead view shows the Space Shuttle Program's last external fuel tank, ET-122, as it is being transported to the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The tank traveled 900 miles by sea, carried in the Pegasus Barge, from NASA's Michoud Assembly Facility in New Orleans. Once inside the VAB, it eventually will be attached to space shuttle Endeavour for the STS-134 mission to the International Space Station targeted to launch Feb. 2011. STS-134 currently is scheduled to be the last mission in the shuttle program. The tank, which is the largest element of the space shuttle stack, was damaged during Hurricane Katrina in August 2005 and restored to flight configuration by Lockheed Martin Space Systems Company employees. Photo credit: NASA/Kevin O'Connell

  11. KSC-2009-5811

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – At Port Canaveral, a tugboat relieves the Liberty Star for the move of the Pegasus barge, carrying external tank 134, through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by the solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  12. KSC-2009-5812

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – At Port Canaveral, a tugboat begins to push the Pegasus barge, carrying external tank 134, through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  13. KSC-2009-5813

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – At Port Canaveral, a tugboat begins to move the Pegasus barge, carrying external tank 134, through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  14. KENNEDY SPACE CENTER, FLA. - A flatbed truck carrying pieces of Columbia debris arrives in the transfer aisle of the Vehicle Assembly Building. The debris is being transferred to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

    NASA Image and Video Library

    2003-09-15

    KENNEDY SPACE CENTER, FLA. - A flatbed truck carrying pieces of Columbia debris arrives in the transfer aisle of the Vehicle Assembly Building. The debris is being transferred to the VAB for permanent storage. More than 83,000 pieces of debris were shipped to KSC during search and recovery efforts in East Texas. That represents about 38 percent of the dry weight of Columbia, equaling almost 85,000 pounds.

  15. KSC-2011-1796

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, media gather outside of Orbiter Processing Facility-2 to photograph space shuttle Endeavour's move, or "rollover," to the Vehicle Assembly Building (VAB). In the VAB, Endeavour will be lifted into a high bay where it will be attached to its external fuel tank and solid rocket boosters for its final and upcoming STS-134 mission. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, spare parts, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA

  16. KSC-2011-1798

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, STS-134 Pilot Gregory H. Johnson and Mission Specialist Roberto Vittori with the European Space Agency accompany space shuttle Endeavour's move, or "rollover," to the Vehicle Assembly Building (VAB). In the VAB, Endeavour will be lifted into a high bay where it will be attached to its external fuel tank and solid rocket boosters for its final and upcoming STS-134 mission. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, spare parts, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA

  17. KSC-2011-1793

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Endeavour approaches the Vehicle Assembly Building, or VAB, on its move from Orbiter Processing Facility-2 where it was processed for its final and upcoming STS-134 mission. In the VAB, Endeavour will be lifted into a high bay where it will be joined to its external fuel tank and solid rocket boosters. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, spare parts, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA/Jack Pfaller

  18. KSC-2011-1794

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, media gather outside of Orbiter Processing Facility-2 to photograph space shuttle Endeavour's move, or "rollover," to the Vehicle Assembly Building (VAB). In the VAB, Endeavour will be lifted into a high bay where it will be attached to its external fuel tank and solid rocket boosters for its final and upcoming STS-134 mission. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, spare parts, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA

  19. KSC-2011-1900

    NASA Image and Video Library

    2011-02-28

    CAPE CANAVERAL, Fla. -- At NASA’s Kennedy Space Center in Florida, space shuttle Endeavour is secured to a transporter for its move, or "rollover" from Orbiter Processing Facility-2 to the Vehicle Assembly Building (VAB). In the VAB, Endeavour will be lifted into a high bay where it will be attached to its external fuel tank and solid rocket boosters for its final mission, STS-134. Endeavour and its STS-134 crew will deliver the Express Logistics Carrier-3, Alpha Magnetic Spectrometer, a high-pressure gas tank, additional spare parts for Dextre and micrometeoroid debris shields to the International Space Station. Launch is targeted for April 19 at 7:48 p.m. EDT. For more information visit, http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts134/index.html. Photo credit: NASA/Jack Pfaller

  20. Space Shuttle Atlantis rolls back to Launch Pad 39A

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Photographed from the top of the Vehicle Assembly Building, Space Shuttle Atlantis creeps along the crawlerway for the 3.4-mile trek to Launch Pad 39A (upper left). In the background is the Atlantic Ocean; on either side is water from the Banana Creek (left) and Banana River (right). The Shuttle has been in the VAB undergoing tests on the solid rocket booster cables. A prior extensive evaluation of NASA's SRB cable inventory on the shelf revealed conductor damage in four (of about 200) cables. Shuttle managers decided to prove the integrity of the system tunnel cables already on Atlantis, causing return of the Shuttle to the VAB a week ago. Launch of Atlantis on STS-98 has been rescheduled to Feb. 7 at 6:11 p.m. EST.

  1. KSC-2011-3036

    NASA Image and Video Library

    2011-04-25

    CAPE CANAVERAL, Fla. - In the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida, workers monitor the progress of external fuel tank, ET-138, for space shuttle Atlantis' STS-135 mission, as it is lifted from its test cell for transfer to high bay-1 for joining with the twin solid rocket boosters on the mobile launcher platform. Shuttle Atlantis' move, or "rollover," from Orbiter Processing Facility-1 to the VAB is targeted for May 10. Once there it will be mated with the external tank and boosters. Atlantis and its crew of four will deliver the Raffaello multipurpose logistics module packed with supplies and spare parts to the International Space Station. STS-135 is targeted to launch June 28, and will be the last spaceflight for the Space Shuttle Program. Photo credit: NASA/Jack Pfaller

  2. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Participants in the ribbon cutting for KSC's new 34,600-square- foot Space Shuttle Main Engine Processing Facility (SSMEPF) gather to talk inside the facility following the ceremony. From left, they are Robert B. Sieck, director of Shuttle Processing; KSC Center Director Roy D. Bridges Jr.; U.S. Congressman Dave Weldon; John Plowden, vice president of Rocketdyne; and Donald R. McMonagle, manager of Launch Integration. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  3. View of Apollo 15 space vehicle on way from VAB to Pad A, Launch Complex 39

    NASA Image and Video Library

    1971-05-11

    S71-33781 (11 May 1971) --- High angle view showing the Apollo 15 (Spacecraft 112/Lunar Module 10/Saturn 510) space vehicle on the way from the Vehicle Assembly Building (VAB) to Pad A, Launch Complex 39, Kennedy Space Center (KSC). The Saturn V stack and its mobile launch tower are atop a huge crawler-transporter. Apollo 15 is scheduled as the fourth manned lunar landing mission by the National Aeronautics and Space Administration (NASA). The crew men will be astronauts David R. Scott, commander; Alfred M. Worden, command module pilot; and James B. Irwin, lunar module pilot. While astronauts Scott and Irwin descend in the Lunar Module (LM) to explore the moon, astronaut Worden will remain with the Command and Service Modules (CSM) in lunar orbit.

  4. VAB Platform K(2) Lift & Install into Highbay 3

    NASA Image and Video Library

    2016-03-07

    A 250-ton crane is used to lower the second half of the K-level work platforms for NASA’s Space Launch System (SLS) rocket into High Bay 3 inside the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The platform will be secured about 86 feet above the VAB floor, on tower E of the high bay. The K work platforms will provide access to the SLS core stage and solid rocket boosters during processing and stacking operations on the mobile launcher. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft.

  5. STS-51 preparation: ACTS, ORFEUS, Discovery in VAB

    NASA Technical Reports Server (NTRS)

    1993-01-01

    In NASA's building AM on Cape Canaveral Air Force Station, STS-51 mission specialist Carl Walz (right) and Deutsche Aerospace technician Gregor Dawidowitsch check over the scientific instruments mounted on the Shuttle Pallet Satellite (SPAS) carrier (38573); The Orbiting and Retrievable Far and Extreme Ultraviolet Spectrometer (ORFEUS) and SPAS is readied for hoisting into a test cell at the Vertical Processing Facility (VPF) (38574); Mating of the Advanced Communications Technology Satellite (ACTS) with the Transfer Orbit Stage (TOS) booster is under way in the Payload Hazardous Servicing Facility (PHSF) (38575); The mated ACTS and TOS are ready to be moved from the PHSF to the Vertical Processsing Facility (VPF) (38576); The orbiter Discovery is rolled into the Vehicle Assembly Building (VAB) for mating with the external tank and twin solid rocket boosters (38577-8).

  6. KSC-98PC-0998

    NASA Image and Video Library

    1998-08-31

    This aerial view shows the Vehicle Assembly Building (VAB) getting a facelift with the repainting of the American flag and replacing of the Bicentennial emblem with the NASA logo. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the 'meatball,' measures 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls.

  7. KSC-2011-5574

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- finds shelter in the Vehicle Assembly Building, or VAB, after rolling from Orbiter Processing Facility-2, or OPF-2. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Ken Thornsley

  8. KSC-2011-5546

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- winds its way from Orbiter Processing Facility-2, or OPF-2, to the Vehicle Assembly Building, or VAB. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Frankie Martin

  9. KSC-2011-5550

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- awaits entry into the Vehicle Assembly Building, or VAB, after rolling from Orbiter Processing Facility-2, or OPF-2. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Frankie Martin

  10. Platform C North Installation

    NASA Image and Video Library

    2016-11-10

    A heavy-lift crane lifts the second half of the C-level work platforms, C north, for NASA’s Space Launch System (SLS) rocket, high up from the transfer aisle of the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. The C platform will be moved into High Bay 3 for installation on the north side of High Bay 3. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. In view below Platform C are several of the previously installed platforms. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  11. Platform C Installation

    NASA Image and Video Library

    2016-10-19

    A heavy-lift crane lifts the first half of the C-level work platforms, C south, for NASA’s Space Launch System (SLS) rocket, up from the transfer aisle floor of the Vehicle Assembly Building (VAB) at NASA’s Kennedy Space Center in Florida. Large Tandemloc bars have been attached to the platform to keep it level during lifting and installation. The C platform will be installed on the south side of High Bay 3. The C platforms are the eighth of 10 levels of work platforms that will surround and provide access to the SLS rocket and Orion spacecraft for Exploration Mission 1. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to VAB High Bay 3, including installation of the new work platforms, to prepare for NASA’s Journey to Mars.

  12. Saturn V Vehicle for the Apollo 4 Mission in the Vehicle Assembly Building

    NASA Technical Reports Server (NTRS)

    1967-01-01

    This photograph depicts the Saturn V vehicle (SA-501) for the Apollo 4 mission in the Vehicle Assembly Building (VAB) at the Kennedy Space Center (KSC). After the completion of the assembly operation, the work platform was retracted and the vehicle was readied to rollout from the VAB to the launch pad. The Apollo 4 mission was the first launch of the Saturn V launch vehicle. Objectives of the unmanned Apollo 4 test flight were to obtain flight information on launch vehicle and spacecraft structural integrity and compatibility, flight loads, stage separation, and subsystems operation including testing of restart of the S-IVB stage, and to evaluate the Apollo command module heat shield. The Apollo 4 was launched on November 9, 1967 from KSC.

  13. An Engineering Look at Space Shuttle and ISS Operations

    NASA Technical Reports Server (NTRS)

    Hernandez, Jose M.

    2004-01-01

    This slide presentation, in Spanish, is an overview of NASA's Space Shuttle operations and preparations for serving the International Space Station. There is information and or views of the shuttle's design, the propulsion system, the external tanks, the foam insulation, the reusable solid rocket motors, the vehicle assembly building (VAB), the mobile launcher platform being moved from the VAB to the launch pad. There is a presentation of some of the current issues with the space shuttle: cracks in the LH2 flow lines, corrosion and pitting, the thermal protection system, and inspection of the thermal protection system while in orbit. The shuttle system has served for more than 20 years, it is still a challenge to re-certify the vehicles for flight. Materials and material science remain as chief concerns for the shuttle,

  14. KSC-2012-5891

    NASA Image and Video Library

    2012-10-19

    CAPE CANAVERAL, Fla. – An Orion mockup spacecraft atop its service module simulator is lifted in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Orion mockup is exact in details on the outside, but mostly empty on the inside. The work in the VAB is crucial to making sure the designs are accurate. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first unpiloted test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  15. KSC-2012-5893

    NASA Image and Video Library

    2012-10-19

    CAPE CANAVERAL, Fla. – An Orion mockup spacecraft atop its service module simulator is lowered onto a transporter in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Orion mockup is exact in details on the outside, but mostly empty on the inside. The work in the VAB is crucial to making sure the designs are accurate. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first unpiloted test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  16. KSC-98pc786

    NASA Image and Video Library

    1998-07-06

    James W. Tibble (pointing at engine), an Engine Systems/Ground Support Equipment team manager for Rocketdyne, discusses the operation of a Space Shuttle Main Engine with Robert B. Sieck, director of Shuttle Processing; U.S. Congressman Dave Weldon; and KSC Center Director Roy D. Bridges Jr. Following the ribbon cutting ceremony for KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF), KSC employees and media explored the facility. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998

  17. KSC-2009-5814

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – A bright sun and blue sky herald the passage of the Pegasus barge, carrying external tank 134, through Port Canaveral. The tugboat will move the barge through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  18. KSC-2009-5816

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – A tugboat moves the Pegasus barge, carrying external tank 134, through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Space Shuttle Atlantis awaits launch on Launch Pad 39A in the background. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  19. KSC-2009-5815

    NASA Image and Video Library

    2009-10-24

    CAPE CANAVERAL, Fla. – The Pegasus barge, carrying external tank 134, passes through a bridge into the river near Port Canaveral. The tugboat will move the barge through the Banana River toward the turn basin near the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Pegasus arrived in Florida after an ocean voyage towed by a solid rocket booster retrieval ship from NASA's Michoud Assembly Facility near New Orleans. After Pegasus docks in the turn basin, the fuel tank will be offloaded and transported into the VAB. ET-134 will be used to launch space shuttle Endeavour on the STS-130 mission to the International Space Station. Launch is targeted for Feb. 4, 2010. For information on the components of the space shuttle and the STS-130 mission, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Jack Pfaller

  20. KSC-03PD-3128

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. Viewed across the turn basin in the Launch Complex 39 Area, the crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB). The journey is in support of engineering analysis vibration tests on the crawler and MLP. The water on the right of the crawlerway is the Banana River. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  1. KSC-03PD-3120

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The crawler transporter slowly moves the Mobile Launcher Platform (MLP), carrying a set of twin solid rocket boosters, away from the Vehicle Assembly Building (VAB) in support of engineering analysis vibration tests on the crawler and MLP. In the distance, at left, is Launch Pad 39A. The water on the right of the crawlerway is the Banana River. The crawler is moving at various speeds up to 1 mph in an effort to achieve vibration data gathering goals as it leaves the VAB and then returns. The boosters are braced at the top for stability. The primary purpose of these rollout tests is to gather data to develop future maintenance requirements on the transport equipment and the flight hardware. Various parts of the MLP and crawler transporter have been instrumented with vibration data collection equipment.

  2. KSC-05PD-1177

    NASA Technical Reports Server (NTRS)

    2005-01-01

    KENNEDY SPACE CENTER, FLA. At NASAs Kennedy Space Center, Space Shuttle Discovery, resting on the Mobile Launcher Platform, rolls into high bay 1 of the Vehicle Assembly Building (VAB). The Shuttle is being rolled back from Launch Pad 39B. It will be demated from its External Tank and lifted into the transfer aisle. On or about June 7, Discovery will be attached to its new tank and Solid Rocket Boosters, which are already in the VAB. Only the 15th rollback in Space Shuttle Program history, the 4.2- mile journey allows additional modifications to be made to the External Tank prior to a safe Return to Flight. Discovery is expected to be rolled back to the launch pad in mid-June for Return to Flight mission STS-114. The launch window extends from July 13 to July 31. [Photo courtesy of Scott Andrews

  3. Aerial view of Launch Complex 39

    NASA Technical Reports Server (NTRS)

    1998-01-01

    In this aerial view looking south can be seen Launch Complex (LC) 39 area, where assembly, checkout and launch of the Space Shuttle Orbiter and its External Tank and twin Solid Rocket Boosters take place. Central to the complex is the tallest building at the center, the Vehicle Assembly Building (VAB). To the immediate left, from top to bottom, are the Orbiter Processing Facility (OPF) High Bay 3 and new engine shop (north side), OPF Modular Office Building, Thermal Protection System Facility, and a crawler-transporter (to its left). In front of the VAB are OPF 1 and OPF 2. At right is the Processing Control Center. West of OPF 3 is the Mobile Launch Platform. In the upper left corner is Launch Pad B; at the far right is the turn basin, with the Press Site located just below it to the right.

  4. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    James W. Tibble (pointing at engine), an Engine Systems/Ground Support Equipment team manager for Rocketdyne, discusses the operation of a Space Shuttle Main Engine with Robert B. Sieck, director of Shuttle Processing; U.S. Congressman Dave Weldon; and KSC Center Director Roy D. Bridges Jr. Following the ribbon cutting ceremony for KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF), KSC employees and media explored the facility. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  5. View of Apollo 15 space vehicle leaving VAB to Pad A, Launch Complex 39

    NASA Image and Video Library

    1971-05-11

    S71-33786 (11 May 1971) --- The 363-feet tall Apollo (Spacecraft 112/Lunar Module 10/Saturn 510) space vehicle which leaves the Vehicle Assembly Building (VAB) to Pad A, Launch Complex 39, Kennedy Space Center (KSC). The Saturn V stack and its mobile launch tower are atop a huge crawler-transporter. Apollo 15 is scheduled as the fourth manned lunar landing mission by the National Aeronautics and Space Administration (NASA) and is scheduled to lift off on July 26, 1971. The crew men will be astronauts David R. Scott, commander; Alfred M. Worden, command module pilot; and James B. Irwin, lunar module pilot. While astronaut Scott and Irwin will descend in the Lunar Module (LM) to explore the moon, astronaut Worden will remain with the Command and Service Modules (CSM) in lunar orbit.

  6. KSC-98pc986

    NASA Image and Video Library

    1998-08-28

    KENNEDY SPACE CENTER, FLA. -- The Vehicle Assembly Building (VAB) gets a facelift with the repainting of the American flag and replacing of the bicentennial emblem with the NASA logo. The painting honors NASA’s 40th anniversary on Oct. 1 and is expected to be complete in mid-September. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," will measure 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls

  7. KSC-98pc996

    NASA Image and Video Library

    1998-08-31

    KENNEDY SPACE CENTER, FLA. -- This aerial view shows the Vehicle Assembly Building (VAB) getting a facelift with the repainting of the American flag and replacing of the bicentennial emblem with the NASA logo. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls

  8. KSC-98pc997

    NASA Image and Video Library

    1998-08-31

    KENNEDY SPACE CENTER, FLA. -- This aerial view shows the Vehicle Assembly Building (VAB) getting a facelift with the repainting of the American flag and replacing of the Bicentennial emblem with the NASA logo. The painting honors NASA's 40th anniversary on Oct. 1 and is expected to be complete in mid-September. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Workers, suspended on platforms from the top of the 525-foot-high VAB, are using rollers and brushes to do the painting. The entire fleet of orbiters is also receiving the addition of the NASA logo on their wings and sidewalls

  9. KSC-2011-5529

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery ventures out in public seemingly "undressed" -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors. The shuttle is rolling from Orbiter Processing Facility-2, or OPF-2, to the Vehicle Assembly Building, or VAB. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Jim Grossmann

  10. KSC-2011-5533

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- has arrived at the door of the Vehicle Assembly Building, or VAB, from Orbiter Processing Facility-2, or OPF-2, in the background. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Jim Grossmann

  11. KSC-2011-5549

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- has arrived at the door of the Vehicle Assembly Building, or VAB, from Orbiter Processing Facility-2, or OPF-2. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Frankie Martin

  12. KSC-2011-5545

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- rolls past Orbiter Processing Facility-3, or OPF-3, at right, on its way from OPF-2 to the Vehicle Assembly Building, or VAB. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Frankie Martin

  13. KSC-2011-5542

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- rolls past the Thermal Protection System Facility, at right, on its way from Orbiter Processing Facility-2, or OPF-2, to the Vehicle Assembly Building, or VAB. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Frankie Martin

  14. KSC-2011-5528

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery, as it is seldom seen in public -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- rolls out of Orbiter Processing Facility-2, or OPF-2, on its way to the Vehicle Assembly Building, or VAB. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Jim Grossmann

  15. KSC-2011-5532

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- rolls past the Thermal Protection System Facility, at right, on its way from Orbiter Processing Facility-2, or OPF-2, to the Vehicle Assembly Building, or VAB. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Jim Grossmann

  16. KSC-2011-5573

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- is welcomed into the Vehicle Assembly Building, or VAB, after its roll from Orbiter Processing Facility-2, or OPF-2. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Ken Thornsley

  17. KSC-2011-5572

    NASA Image and Video Library

    2011-07-13

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, space shuttle Discovery -- its nose encased in protective plastic, its cockpit windows covered, and strongbacks attached to its payload bay doors -- rolls out of Orbiter Processing Facility-2, or OPF-2, on its move to the Vehicle Assembly Building, or VAB. Discovery will be stored inside the VAB for approximately one month while shuttle Atlantis undergoes processing in OPF-2 following its final mission, STS-135. Discovery flew its 39th and final mission, STS-133, in February and March 2011, and currently is being prepared for public display at the Smithsonian's National Air and Space Museum Steven F. Udvar-Hazy Center in Virginia. For more information about Discovery's Transition and Retirement, visit www.nasa.gov/mission_pages/shuttle/launch/discovery_rss_collection_archive_1.html. Photo credit: NASA/Ken Thornsley

  18. KENNEDY SPACE CENTER, FLA. -- Endeavour backs out of the Orbiter Processing Facility for temporary transfer to the Vehicle Assembly Building. The move allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- Endeavour backs out of the Orbiter Processing Facility for temporary transfer to the Vehicle Assembly Building. The move allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  19. Accuracy assessment methods of tissue marker clip placement after 11-gauge vacuum-assisted stereotactic breast biopsy: comparison of measurements using direct and conventional methods.

    PubMed

    Yatake, Hidetoshi; Sawai, Yuka; Nishi, Toshio; Nakano, Yoshiaki; Nishimae, Ayaka; Katsuda, Toshizo; Yabunaka, Koichi; Takeda, Yoshihiro; Inaji, Hideo

    2017-07-01

    The objective of the study was to compare direct measurement with a conventional method for evaluation of clip placement in stereotactic vacuum-assisted breast biopsy (ST-VAB) and to evaluate the accuracy of clip placement using the direct method. Accuracy of clip placement was assessed by measuring the distance from a residual calcification of a targeted calcification clustered to a clip on a mammogram after ST-VAB. Distances in the craniocaudal (CC) and mediolateral oblique (MLO) views were measured in 28 subjects with mammograms recorded twice or more after ST-VAB. The difference in the distance between the first and second measurements was defined as the reproducibility and was compared with that from a conventional method using a mask system with overlap of transparent film on the mammogram. The 3D clip-to-calcification distance was measured using the direct method in 71 subjects. The reproducibility of the direct method was higher than that of the conventional method in CC and MLO views (P = 0.002, P < 0.001). The median 3D clip-to-calcification distance was 2.8 mm, with an interquartile range of 2.0-4.8 mm and a range of 1.1-36.3 mm. The direct method used in this study was more accurate than the conventional method, and gave a median 3D distance of 2.8 mm between the calcification and clip.

  20. Free-Flight Test Results of Scale Models Simulating Viking Parachute/Lander Staging

    NASA Technical Reports Server (NTRS)

    Polutchko, Robert J.

    1973-01-01

    This report presents the results of Viking Aerothermodynamics Test D4-34.0. Motion picture coverage of a number of Scale model drop tests provides the data from which time-position characteristics as well as canopy shape and model system attitudes are measured. These data are processed to obtain the instantaneous drag during staging of a model simulating the Viking decelerator system during parachute staging at Mars. Through scaling laws derived prior to test (Appendix A and B) these results are used to predict such performance of the Viking decelerator parachute during staging at Mars. The tests were performed at the NASA/Kennedy Space Center (KSC) Vertical Assembly Building (VAB). Model assemblies were dropped 300 feet to a platform in High Bay No. 3. The data consist of an edited master film (negative) which is on permanent file in the NASA/LRC Library. Principal results of this investigation indicate that for Viking parachute staging at Mars: 1. Parachute staging separation distance is always positive and continuously increasing generally along the descent path. 2. At staging, the parachute drag coefficient is at least 55% of its prestage equilibrium value. One quarter minute later, it has recovered to its pre-stage value.

  1. Self-esteem in children after traumatic brain injury: an exploratory study.

    PubMed

    Hawley, Carol A

    2012-01-01

    Children with a traumatic brain injury (TBI) often have difficulties in adjusting to their injury and altered abilities, and may be at risk of low self-esteem and loss of confidence. However, few studies have examined self-esteem in this client group. The current study measured the self-esteem of a group of children who were, on average, two years post-TBI and compared this to their performance on other psychometric measures. Participants were 96 children with TBI and 31 peer controls, their parents and teachers. Self-esteem was measured using the Coopersmith Self-esteem Inventory (CSEI). CSEI scores were compared with performance on Wechsler Intelligence Scales (WISC-III), Hospital Anxiety and Depression Scale (HADS); Children's Memory Scale (CMS), Vineland Adaptive Behaviour Scales (VABS) and Parental Stress Index (PSI). Self-esteem was highly correlated with IQ; HADS anxiety and depression; and parental stress (p< 0.001). Children with TBI had significantly lower self-esteem than controls and population norms (p=0.015). Many children with TBI demonstrate low self-esteem and this is closely linked with anxiety and depression. This may hamper academic performance and could lead to further psychosocial problems. It is recommended that self-esteem is routinely assessed after brain injury and rehabilitation strategies implemented to promote a sense of self-worth.

  2. STS-71 hardware assembly view

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Lockheed Space Operations Company workers in the Extended Duration Orbiter (EDO) Facility, located inside the Vehicle Assembly Building (VAB), carefully hoist the Orbiter Docking System (ODS) from its shipping container into a test stand. The ODS was ship

  3. KSC-2010-4899

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- This panoramic image shows the Pegasus Barge carrying the Space Shuttle Program's last external fuel tank, ET-122, through the Port Canaveral locks on its way to the Turn Basin at NASA's Kennedy Space Center in Florida. Once docked, the tank will be offloaded from the barge and transported to the Vehicle Assembly Building (VAB). The tank traveled 900 miles by sea, carried in the barge, from NASA's Michoud Assembly Facility in New Orleans. Once inside the VAB, it eventually will be attached to space shuttle Endeavour for the STS-134 mission to the International Space Station targeted to launch Feb. 2011. STS-134 currently is scheduled to be the last mission in the shuttle program. The tank, which is the largest element of the space shuttle stack, was damaged during Hurricane Katrina in August 2005 and restored to flight configuration by Lockheed Martin Space Systems Company employees. Photo credit: NASA/Frankie Martin

  4. KSC-2012-4319

    NASA Image and Video Library

    2012-08-06

    CAPE CANAVERAL, Fla. – The Orion mockup spacecraft sits atop its service module simulator in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first uncrewed test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. The Orion mockup is exact in details on the outside, but mostly empty on the inside except for four mockup astronaut seats and hatch. The work in the VAB is crucial to making sure the designs are accurate. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  5. KSC-2012-4320

    NASA Image and Video Library

    2012-08-06

    CAPE CANAVERAL, Fla. – The Orion mockup spacecraft sits atop its service module simulator in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. To the left is the aerodynamic shell that will cover the capsule during launch. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first uncrewed test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. The Orion mockup is exact in details on the outside, but mostly empty on the inside except for four mockup astronaut seats and hatch. The work in the VAB is crucial to making sure the designs are accurate. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  6. KSC-2012-4316

    NASA Image and Video Library

    2012-08-06

    CAPE CANAVERAL, Fla. – The Orion mockup spacecraft sits atop its service module simulator in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first uncrewed test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. The Orion mockup is exact in details on the outside, but mostly empty on the inside except for four mockup astronaut seats and hatch. The work in the VAB is crucial to making sure the designs are accurate. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  7. KSC-99pp0552

    NASA Image and Video Library

    1999-05-16

    KENNEDY SPACE CENTER, FLA. -- Standing inside a protective tent around the external tank of Space Shuttle Discovery in the Vehicle Assembly Building (VAB), United Space Alliance technician Don Pataky repairs divots caused by hail storms. The Shuttle was rolled back from Pad 39B to the VAB for repairs because access to all of the damaged areas was not possible at the pad. The work is expected to take two to three days, allowing Discovery to roll back to the pad late this week for launch of mission STS-96, the 94th launch in the Space Shuttle Program. Liftoff will occur no earlier than May 27. STS-96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student-shared experiment

  8. KSC-99pp0553

    NASA Image and Video Library

    1999-05-18

    KENNEDY SPACE CENTER, FLA. -- In the Vehicle Assembly Building (VAB), United Space Alliance technician Robert Williams sands the repaired areas near the top of Space Shuttle Discovery's external tank. Repairs were required for damage caused by hail during recent storms. Because access to all of the damaged areas was not possible at the pad, the Shuttle was rolled back from Pad 39B to the VAB. The work is expected to take two to three days, allowing Discovery to roll back to the pad late this week for launch of mission STS-96, the 94th launch in the Space Shuttle Program. Liftoff will occur no earlier than May 27. STS-96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student-shared experiment

  9. KSC-98pc903

    NASA Image and Video Library

    1998-08-11

    Painters are suspended on platforms from the top of the 525-foot-high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag. The flag spans an area 209 feet by 110 feet and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. In addition to the flag, the Bicentennial Emblem on the other side of the VAB doors is being replaced by the NASA logo, honoring NASA’s 40th anniversary (in October). The logo covers an area 110 feet by 132 feet. Work is expected to be completed in mid-September

  10. KSC-98pc904

    NASA Image and Video Library

    1998-08-11

    Painters are suspended on platforms from the top of the 525-foot-high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag and NASA logo. The flag spans an area 209 feet by 110 feet and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The previous Bicentennial Emblem on the other side of the VAB doors is being replaced by the NASA logo, honoring NASA’s 40th anniversary (in October). The logo covers an area 110 feet by 132 feet. The painting platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. Work is expected to be completed in mid-September

  11. VAB Platform K(2) Lift & Install into Highbay 3

    NASA Image and Video Library

    2016-03-07

    Preparations are underway to lift the second half of the K-level work platforms for NASA’s Space Launch System (SLS) rocket up from High Bay 4 inside the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The platform will be lifted up and over the transfer aisle and then lowered into High Bay 3 for installation. It will be secured about 86 feet above the VAB floor, on tower E of the high bay. The K work platforms will provide access to the SLS core stage and solid rocket boosters during processing and stacking operations on the mobile launcher. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft.

  12. VAB Platform K(2) Lift & Install into Highbay 3

    NASA Image and Video Library

    2016-03-07

    A 250-ton crane is used to lift the second half of the K-level work platforms for NASA’s Space Launch System (SLS) rocket high above the transfer aisle inside the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The platform is being lifted up for transfer into High Bay 3 for installation. The platform will be secured about 86 feet above the VAB floor, on tower E of the high bay. The K work platforms will provide access to the SLS core stage and solid rocket boosters during processing and stacking operations on the mobile launcher. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft.

  13. VAB Platform K(2) Lift & Install into Highbay 3

    NASA Image and Video Library

    2016-03-07

    A 250-ton crane is used to lift the second half of the K-level work platforms for NASA’s Space Launch System (SLS) rocket up from High Bay 4 inside the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The platform will be lifted up and over the transfer aisle and then lowered into High Bay 3 for installation. It will be secured about 86 feet above the VAB floor, on tower E of the high bay. The K work platforms will provide access to the SLS core stage and solid rocket boosters during processing and stacking operations on the mobile launcher. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft.

  14. VAB Platform K(2) Lift & Install into Highbay 3

    NASA Image and Video Library

    2016-03-07

    A 250-ton crane is used to lift the second half of the K-level work platforms for NASA’s Space Launch System (SLS) rocket up from High Bay 4 inside the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The platform is being lifted up and over the transfer aisle and will be lowered into High Bay 3 for installation. It will be secured about 86 feet above the VAB floor, on tower E of the high bay. The K work platforms will provide access to the SLS core stage and solid rocket boosters during processing and stacking operations on the mobile launcher. The Ground Systems Development and Operations Program is overseeing upgrades and modifications to High Bay 3 to support processing of the SLS and Orion spacecraft. A total of 10 levels of new platforms, 20 platform halves altogether, will surround the SLS rocket and Orion spacecraft.

  15. Aerial of the VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    In the early morning, flocks of birds soar over the Banana River, whose waters reflect the Vehicle Assembly Building , bathed in a pink glow from post-dawn light. Next to the VAB, on the left, is the Launch Control Center. The rectangular building closer to the water at left is the Operations Support Building. At right is the Rotation/Processing Facility. The birds are a common sight at KSC since the Center shares a boundary with the Merritt Island National Wildlife Refuge. The Refuge encompasses 92,000 acres that are a habitat for more than 331 species of birds, 31 mammals, 117 fishes, and 65 amphibians and reptiles. The marshes and open water of the refuge provide wintering areas for 23 species of migratory waterfowl, as well as a year-round home for great blue herons, great egrets, wood storks, cormorants, brown pelicans and other species of marsh and shore birds, as well as a variety of insects.

  16. KENNEDY SPACE CENTER, FLA. - The red NASA engine hauls its cargo toward Titusville, Fla. The containers enclose segments of a solid rocket booster being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

    NASA Image and Video Library

    2004-01-30

    KENNEDY SPACE CENTER, FLA. - The red NASA engine hauls its cargo toward Titusville, Fla. The containers enclose segments of a solid rocket booster being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

  17. KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis is backed out of the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis is backed out of the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  18. KENNEDY SPACE CENTER, FLA. -- Endeavour begins rolling out of the Orbiter Processing Facility for temporary transfer to the Vehicle Assembly Building. The move allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- Endeavour begins rolling out of the Orbiter Processing Facility for temporary transfer to the Vehicle Assembly Building. The move allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  19. KENNEDY SPACE CENTER, FLA. -- Endeavour is towed toward the Vehicle Assembly Building for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- Endeavour is towed toward the Vehicle Assembly Building for temporary storage. The orbiter has been moved from the Orbiter Processing Facility (OPF) to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  20. KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis rolls into the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis rolls into the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  1. KENNEDY SPACE CENTER, FLA. -- Endeavour is ready to be rolled out of the Orbiter Processing Facility for temporary transfer to the Vehicle Assembly Building. The move allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

    NASA Image and Video Library

    2004-01-09

    KENNEDY SPACE CENTER, FLA. -- Endeavour is ready to be rolled out of the Orbiter Processing Facility for temporary transfer to the Vehicle Assembly Building. The move allows work to be performed in the OPF that can only be accomplished while the bay is empty. Work scheduled in the OPF includes annual validation of the bay’s cranes, work platforms, lifting mechanisms and jack stands. Endeavour will remain in the VAB for approximately 12 days, then return to the OPF.

  2. KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis is back inside the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis is back inside the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  3. KENNEDY SPACE CENTER, FLA. -- The orbiter Atlantis is backed away from the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. -- The orbiter Atlantis is backed away from the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  4. KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis rolls toward the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis rolls toward the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  5. KENNEDY SPACE CENTER, FLA. -- The orbiter Atlantis is backed out of the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. -- The orbiter Atlantis is backed out of the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  6. KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis rolls out of the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis rolls out of the Vehicle Assembly Building for transfer back to the Orbiter Processing Facility. Atlantis spent 10 days in the VAB to allow work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  7. KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis is towed back to the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. - The orbiter Atlantis is towed back to the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  8. GENERAL VIEW OF VEHICLE ACCESS PLATFORM CNORTH, HB3, FACING NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM C-NORTH, HB-3, FACING NORTHEAST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  9. GENERAL VIEW OF VEHICLE ACCESS PLATFORM ENORTH, HB3, FACING NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM E-NORTH, HB-3, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  10. GENERAL VIEW OF VEHICLE ACCESS PLATFORM ENORTH, HB3, FACING NORTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM E-NORTH, HB-3, FACING NORTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  11. GENERAL VIEW OF VEHICLE ACCESS PLATFORM DNORTH, HB3, FACING NORTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM D-NORTH, HB-3, FACING NORTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  12. GENERAL VIEW OF NORTH VEHICLE ACCESS PLATFORMS, HB3, FACING NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF NORTH VEHICLE ACCESS PLATFORMS, HB-3, FACING NORTHEAST TOWARDS CEILING - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  13. GENERAL VIEW OF VEHICLE ACCESS PLATFORM BNORTH, HB3, FACING NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM B-NORTH, HB-3, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  14. GENERAL VIEW OF VEHICLE ACCESS PLATFORM DNORTH, HB3, FACING NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM D-NORTH, HB-3, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  15. GENERAL VIEW OF NORTH VEHICLE ACCESS PLATFORMS, HB3, FACING NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF NORTH VEHICLE ACCESS PLATFORMS, HB-3, FACING NORTH TOWARDS FLOOR - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  16. GENERAL VIEW OF VEHICLE ACCESS PLATFORM BNORTH, HB3, FACING NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM B-NORTH, HB-3, FACING NORTHEAST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  17. GENERAL VIEW OF VEHICLE ACCESS PLATFORM CNORTH, HB3, FACING NORTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF VEHICLE ACCESS PLATFORM C-NORTH, HB-3, FACING NORTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  18. Center Planning and Development: Multi-User Spaceport Initiatives

    NASA Technical Reports Server (NTRS)

    Kennedy, Christopher John

    2015-01-01

    The Vehicle Assembly building at NASAs Kennedy Space Center has been used since 1966 to vertically assemble every launch vehicle, since the Apollo Program, launched from Launch Complex 39 (LC-39). After the cancellation of the Constellation Program in 2010 and the retirement of the Space Shuttle Program in 2011, the VAB faced an uncertain future. As the Space Launch System (SLS) gained a foothold as the future of American spaceflight to deep space, NASA was only using a portion of the VABs initial potential. With three high bays connected to the Crawler Way transportation system, the potential exists for up to three rockets to be simultaneously processed for launch. The Kennedy Space Center (KSC) Master plan, supported by the Center Planning and Development (CPD) Directorate, is guiding Kennedy toward a 21st century multi-user spaceport. This concept will maintain Kennedy as the United States premier gateway to space and provide multi-user operations through partnerships with the commercial aerospace industry. Commercial aerospace companies, now tasked with transporting cargo and, in the future, astronauts to the International Space Station (ISS) via the Commercial Resupply Service (CRS) and Commercial Crew Program (CCP), are a rapidly growing industry with increasing capabilities to make launch operations more economical for both private companies and the government. Commercial operations to Low Earth Orbit allow the government to focus on travel to farther destinations through the SLS Program. With LC-39B designated as a multi-use launch pad, companies seeking to use it will require an integration facility to assemble, integrate, and test their launch vehicle. An Announcement for Proposals (AFP) was released in June, beginning the process of finding a non-NASA user for High Bay 2 (HB2) and the Mobile Launcher Platforms (MLPs). An Industry Day, a business meeting and tour for interested companies and organizations, was also arranged to identify and answer any additional questions posed by potential proposers. After amending the AFP and posting additional material for potential users to consider, proposals are being accepted until July 31, at which point they will be evaluated to determine the proposer which best meets the objectives of the government. By identifying VAB HB2 as available and seeking proposals from the commercial sector for VAB HB2 and MLP use, Center Planning and Development is ensuring Kennedy Space Centers relevance in the evolving launch industry of the 21st century.

  19. VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. 1N12, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  20. VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. 1N12, FACING SOUTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  1. GENERAL VIEW OF THE MAIN FLOOR LEVEL, PLATFORM DSOUTH, HB3, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF THE MAIN FLOOR LEVEL, PLATFORM D-SOUTH, HB-3, FACING NORTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  2. DETAIL VIEW OF ELECTRONICS TEST AREA, FLIGHT KITS FACILITY, ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF ELECTRONICS TEST AREA, FLIGHT KITS FACILITY, ROOM NO. 1N12, FACING WEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  3. GENERAL VIEW OF THE BRIDGE CRANE USED IN HB3 AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF THE BRIDGE CRANE USED IN HB-3 AND HB-4, FACING SOUTHEAST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  4. DETAIL VIEW OF VIDEO CAMERA, MAIN FLOOR LEVEL, PLATFORM ESOUTH, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF VIDEO CAMERA, MAIN FLOOR LEVEL, PLATFORM E-SOUTH, HB-3, FACING SOUTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  5. VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING SOUTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  6. DETAIL VIEW OF TESTING EQUIPMENT, REMOTE MANIPULATOR SYSTEM LAB, ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF TESTING EQUIPMENT, REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING SOUTHEAST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  7. VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  8. Saint or sinner? Teacher perceptions of a child with traumatic brain injury.

    PubMed

    Hawley, C A

    2005-01-01

    To examine influences on classroom performance and behaviour following traumatic brain injury (TBI). A case-study of one child who suffered a moderate TBI, with frontal brain damage, aged 8, followed up at ages 12 and 13 years. Parents and child were interviewed to establish pre- and post-injury behaviour and functioning. All 19 teachers who taught the child reported on classroom performance, behaviour and educational achievement in each of their subjects. The child completed a comprehensive neuropsychological assessment battery including the Weschler Intelligence Scale for Children (WISC-III(UK)), Children's Memory Scale (CMS) and Vineland Adaptive Behaviour Scales (VABS). This child demonstrated above-average intelligence and good attention/concentration on the CMS. However, he was unable to focus or maintain attention in most classroom situations. His behaviour was erratic and disruptive in class and at home. At 5-year follow-up, his behaviour had deteriorated in both home and school situations, particularly in less structured environments. Teachers of more structured subjects (maths and science) perceived the child as excitable but performing at average or above-average levels, whereas teachers of less structured subjects (art, drama, music) perceived him to be 'attention-seeking' and very disruptive in class. The influences of environmental factors are discussed.

  9. Unified continuum damage model for matrix cracking in composite rotor blades

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pollayi, Hemaraju; Harursampath, Dineshkumar

    This paper deals with modeling of the first damage mode, matrix micro-cracking, in helicopter rotor/wind turbine blades and how this effects the overall cross-sectional stiffness. The helicopter/wind turbine rotor system operates in a highly dynamic and unsteady environment leading to severe vibratory loads present in the system. Repeated exposure to this loading condition can induce damage in the composite rotor blades. These rotor/turbine blades are generally made of fiber-reinforced laminated composites and exhibit various competing modes of damage such as matrix micro-cracking, delamination, and fiber breakage. There is a need to study the behavior of the composite rotor system undermore » various key damage modes in composite materials for developing Structural Health Monitoring (SHM) system. Each blade is modeled as a beam based on geometrically non-linear 3-D elasticity theory. Each blade thus splits into 2-D analyzes of cross-sections and non-linear 1-D analyzes along the beam reference curves. Two different tools are used here for complete 3-D analysis: VABS for 2-D cross-sectional analysis and GEBT for 1-D beam analysis. The physically-based failure models for matrix in compression and tension loading are used in the present work. Matrix cracking is detected using two failure criterion: Matrix Failure in Compression and Matrix Failure in Tension which are based on the recovered field. A strain variable is set which drives the damage variable for matrix cracking and this damage variable is used to estimate the reduced cross-sectional stiffness. The matrix micro-cracking is performed in two different approaches: (i) Element-wise, and (ii) Node-wise. The procedure presented in this paper is implemented in VABS as matrix micro-cracking modeling module. Three examples are presented to investigate the matrix failure model which illustrate the effect of matrix cracking on cross-sectional stiffness by varying the applied cyclic load.« less

  10. DETAIL VIEW OF THE BRIDGE CRANE HOOKS USED IN HB3 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF THE BRIDGE CRANE HOOKS USED IN HB-3 AND HB-4, FACING SOUTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  11. Upgrade of ductal carcinoma in situ on core biopsies to invasive disease at final surgery: a retrospective review across the Scottish Breast Screening Programme.

    PubMed

    Sim, Y T; Litherland, J; Lindsay, E; Hendry, P; Brauer, K; Dobson, H; Cordiner, C; Gagliardi, T; Smart, L

    2015-05-01

    To identify factors affecting upgrade rates from B5a (non-invasive) preoperative core biopsies to invasive disease at surgery and ways to improve screening performance. This was a retrospective analysis of 1252 cases of B5a biopsies across all six Scottish Breast Screening Programmes (BSPs), ranging between 2004 and 2012. Final surgical histopathology was correlated with radiological and biopsy factors. Data were analysed using basic Microsoft Excel and standard Chi-squared test used for evaluating statistical significance. B5a upgrade rates for the units ranged from 19.2% to 29.2%, with an average of 23.6%. Mean sizes of invasive tumours were small (3-11 mm). The upgrade rate was significantly higher for cases where the main mammographic abnormality was mass, distortion, or asymmetry, compared with micro-calcification alone (33.2% versus 21.7%, p = 0.0004). The upgrade rate was significantly lower with the use of large-volume vacuum-assisted biopsy (VAB) devices than 14 G core needles (19.9% versus 26%, p = 0.013); in stereotactic than ultrasound-guided biopsies (21.2% versus 36.1%, p < 0.001). Heterogeneity of data from different centres limited evaluation of other potential factors. Upgrade rates are lower for cases with micro-calcification as the sole mammographic feature with the use of VAB devices. Nevertheless, there is variation in practice across Scottish BSPs, including first-line biopsy technique and/or device; and it is of interest that a few centres maintain low upgrade rates despite not using VAB routinely for biopsy of micro-calcification. Copyright © 2015 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  12. Structures of closed and open states of a voltage-gated sodium channel

    PubMed Central

    Lenaeus, Michael J.; Gamal El-Din, Tamer M.; Ramanadane, Karthik; Pomès, Régis; Zheng, Ning; Catterall, William A.

    2017-01-01

    Bacterial voltage-gated sodium channels (BacNavs) serve as models of their vertebrate counterparts. BacNavs contain conserved voltage-sensing and pore-forming domains, but they are homotetramers of four identical subunits, rather than pseudotetramers of four homologous domains. Here, we present structures of two NaVAb mutants that capture tightly closed and open states at a resolution of 2.8–3.2 Å. Introduction of two humanizing mutations in the S6 segment (NaVAb/FY: T206F and V213Y) generates a persistently closed form of the activation gate in which the intracellular ends of the four S6 segments are drawn tightly together to block ion permeation completely. This construct also revealed the complete structure of the four-helix bundle that forms the C-terminal domain. In contrast, truncation of the C-terminal 40 residues in NavAb/1–226 captures the activation gate in an open conformation, revealing the open state of a BacNav with intact voltage sensors. Comparing these structures illustrates the full range of motion of the activation gate, from closed with its orifice fully occluded to open with an orifice of ∼10 Å. Molecular dynamics and free-energy simulations confirm designation of NaVAb/1–226 as an open state that allows permeation of hydrated Na+, and these results also support a hydrophobic gating mechanism for control of ion permeation. These two structures allow completion of a closed–open–inactivated conformational cycle in a single voltage-gated sodium channel and give insight into the structural basis for state-dependent binding of sodium channel-blocking drugs. PMID:28348242

  13. Probabilistic Survivability Versus Time Modeling

    NASA Technical Reports Server (NTRS)

    Joyner, James J., Sr.

    2015-01-01

    This technical paper documents Kennedy Space Centers Independent Assessment team work completed on three assessments for the Ground Systems Development and Operations (GSDO) Program to assist the Chief Safety and Mission Assurance Officer (CSO) and GSDO management during key programmatic reviews. The assessments provided the GSDO Program with an analysis of how egress time affects the likelihood of astronaut and worker survival during an emergency. For each assessment, the team developed probability distributions for hazard scenarios to address statistical uncertainty, resulting in survivability plots over time. The first assessment developed a mathematical model of probabilistic survivability versus time to reach a safe location using an ideal Emergency Egress System at Launch Complex 39B (LC-39B); the second used the first model to evaluate and compare various egress systems under consideration at LC-39B. The third used a modified LC-39B model to determine if a specific hazard decreased survivability more rapidly than other events during flight hardware processing in Kennedys Vehicle Assembly Building (VAB).Based on the composite survivability versus time graphs from the first two assessments, there was a soft knee in the Figure of Merit graphs at eight minutes (ten minutes after egress ordered). Thus, the graphs illustrated to the decision makers that the final emergency egress design selected should have the capability of transporting the flight crew from the top of LC 39B to a safe location in eight minutes or less. Results for the third assessment were dominated by hazards that were classified as instantaneous in nature (e.g. stacking mishaps) and therefore had no effect on survivability vs time to egress the VAB. VAB emergency scenarios that degraded over time (e.g. fire) produced survivability vs time graphs that were line with aerospace industry norms.

  14. Clinical outcomes of an early intervention program for preschool children with Autism Spectrum Disorder in a community group setting.

    PubMed

    Eapen, Valsamma; Crnčec, Rudi; Walter, Amelia

    2013-01-07

    Available evidence indicates that early intervention programs, such as the Early Start Denver Model (ESDM), can positively affect key outcomes for children with Autism Spectrum Disorder (ASD). However, programs involving resource intensive one-to-one clinical intervention are not readily available or deliverable in the community, resulting in many children with ASD missing out on evidence-based intervention during their early and most critical preschool years. This study evaluated the effectiveness of the ESDM for preschool-aged children with ASD using a predominantly group-based intervention in a community child care setting. Participants were 26 children (21 male) with ASD with a mean age of 49.6 months. The ESDM, a comprehensive early intervention program that integrates applied behaviour analysis with developmental and relationship-based approaches, was delivered by trained therapists during the child's attendance at a child care centre for preschool-aged children with ASD. Children received 15-20 hours of group-based, and one hour of one-to-one, ESDM intervention per week. The average intervention period was ten months. Outcome measures were administered pre- and post-intervention, and comprised a developmental assessment - the Mullen Scales of Early Learning (MSEL); and two parent-report questionnaires - the Social Communication Questionnaire (SCQ) and Vineland Adaptive Behaviours Scales-Second Edition (VABS-II). Statistically significant post-intervention improvements were found in children's performance on the visual reception, receptive language and expressive language domains of the MSEL in addition to their overall intellectual functioning, as assessed by standardised developmental quotients. Parents reported significant increases in their child's receptive communication and motor skills on the VABS-II, and a significant decrease in autism-specific features on the SCQ. These effects were of around medium size, and appeared to be in excess of what may have been expected due to maturation. Nonetheless, these results need to be confirmed in a controlled study. This study suggests community dissemination of the ESDM using predominantly group-based intervention may be an effective intervention. Making the ESDM accessible to the wider ASD community in child care settings has the potential for significant clinical and economic benefits. Further studies are indicated in this area, including those with younger children, and which incorporate a control group and standardised ASD assessments. This trial is registered with the Australian New Zealand Clinical Trials Registry: Registry number ACTRN12612000461897.

  15. Aerial photo shows burned brush at KSC with VAB in background

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Smoke rising from the smoldering brush on Kennedy Space Center illustrates the hazardous fire conditions that exist throughout Central Florida. The 525-foot tall Vehicle Assembly Building is in the background. The site is between Kennedy Parkway North and the Indian River.

  16. Atlantis is lowered to external stack in the VAB

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. -- In Vehicle Assembly Building high bay 1, the orbiter Atlantis is being lowered into position for mating to its external tank/solid rocket booster stack. Space Shuttle Atlantis is scheduled to launch on mission STS-104 in early July.

  17. KSC-91PC-0219

    NASA Image and Video Library

    1990-12-20

    CAPE CANAVERAL, Fla. – The orbiter Discovery, its wheels retracted atop the orbiter transporter, rolls over from the OPF high bay to the VAB. Discovery is slated to lift off in March on mission STS-39, a DoD flight carrying a crew of seven. Photo credit: NASA

  18. Shuttle Boosters stacked in the VAB

    NASA Image and Video Library

    2007-01-04

    Workers continue stacking the solid rocket boosters in highbay 1 inside Kennedy Space Center's Vehicle Assembly Building. The solid rocket boosters are being prepared for NASA's next Space Shuttle launch, mission STS-117. The mission is scheduled to launch aboard Atlantis no earlier than March 16, 2007.

  19. DETAIL VIEW OF A HANDHELD “BUMPER,” USED TO AID IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF A HANDHELD “BUMPER,” USED TO AID IN POSITIONING THE ORBITER DURING STACKING PROCEDURES - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  20. First stage of Saturn launch vehicle in KSC Vehicle Assembly Building

    NASA Technical Reports Server (NTRS)

    1968-01-01

    The first (S-1C) stage of the Saturn 505 launch vehicle being prepared for erection in the high bay area of the Kennedy Space Center's (KSC) Vehicle Assembly Building (VAB). Saturn 505 is the launch vehicle for the Apollo 10 mission.

  1. KSC-2012-5894

    NASA Image and Video Library

    2012-10-19

    CAPE CANAVERAL, Fla. – An Orion mockup spacecraft atop its service module simulator is lowered onto a transporter in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Orion mockup is exact in details on the outside, but mostly empty on the inside. The work in the VAB is crucial to making sure the designs are accurate. Visible in the background on the left is the space shuttle Atlantis being readied for its move to the Kennedy Space Center Visitor Complex. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first unpiloted test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  2. KSC-2012-5892

    NASA Image and Video Library

    2012-10-19

    CAPE CANAVERAL, Fla. – An Orion mockup spacecraft atop its service module simulator is lifted in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Orion mockup is exact in details on the outside, but mostly empty on the inside. The work in the VAB is crucial to making sure the designs are accurate. Visible in the background on the left is the space shuttle Atlantis being readied for its move to the Kennedy Space Center Visitor Complex. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first unpiloted test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  3. KSC-2012-5895

    NASA Image and Video Library

    2012-10-19

    CAPE CANAVERAL, Fla. – An Orion mockup spacecraft atop its service module simulator is lowered onto a transporter in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. The Orion mockup is exact in details on the outside, but mostly empty on the inside. The work in the VAB is crucial to making sure the designs are accurate. Visible in the background on the left is the space shuttle Atlantis being readied for its move to the Kennedy Space Center Visitor Complex. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first unpiloted test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  4. KSC-98pc783

    NASA Image and Video Library

    1998-07-06

    KSC Center Director Roy D. Bridges Jr. and U.S. Congressman Dave Weldon (holding scissors) cut the ribbon at a ceremony on July 6 to open KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF). Joining in the ribbon cutting are (left) Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; Marvin L. Jones, director of Installation Operations; Donald R. McMonagle, manager of Launch Integration; (right) Wade Ivey of Ivey Construction, Inc.; Robert B. Sieck, director of Shuttle Processing; and John Plowden, vice president of Rocketdyne. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998

  5. KSC-99pp0539

    NASA Image and Video Library

    1999-05-16

    KENNEDY SPACE CENTER, FLA. -- Inside High Bay 1 of the Vehicle Assembly Building (VAB) Mike Sestile, with United Space Alliance, draws circles around divots in the foam insulation on the top of the external tank of Space Shuttle Discovery. About 150 divots were caused by hail during recent storms. The Shuttle was rolled back from Pad 39B to the VAB for repairs because access to all of the damaged areas was not possible at the pad. The work is expected to take two to three days, allowing Discovery to roll back to the pad as early as May 20 for launch of mission STS-96, the 94th launch in the Space Shuttle Program. Liftoff will occur no earlier than May 27. STS-96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student-shared experiment

  6. KSC-99pp0538

    NASA Image and Video Library

    1999-05-16

    KENNEDY SPACE CENTER, FLA. -- Inside High Bay 1 of the Vehicle Assembly Building (VAB), John Blue, with United Space Alliance, points to one of the divots in the foam insulation on the external tank of Space Shuttle Discovery. About 150 divots were caused by hail during recent storms. The Shuttle was rolled back from Pad 39B to the VAB for repairs because access to all of the damaged areas was not possible at the pad. The work is expected to take two to three days, allowing Discovery to roll back to the pad as early as May 20 for launch of mission STS-96, the 94th launch in the Space Shuttle Program. Liftoff will occur no earlier than May 27. STS-96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student-shared experiment

  7. KSC-99pp0537

    NASA Image and Video Library

    1999-05-16

    KENNEDY SPACE CENTER, FLA. -- Inside High Bay 1 of the Vehicle Assembly Building (VAB) John Blue, with United Space Alliance, and Jorge Rivera, with NASA, look at the dings in the foam insulation on the external tank of Space Shuttle Discovery. About 150 dings were caused by hail during recent storms. The Shuttle was rolled back from Pad 39B to the VAB for repairs because access to all of the damaged areas was not possible at the pad. The work is expected to take two to three days, allowing Discovery to roll back to the pad as early as May 20 for launch of mission STS-96, the 94th launch in the Space Shuttle Program. Liftoff will occur no earlier than May 27. STS-96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student-shared experiment

  8. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Participants in the ribbon cutting for KSC's new 34,600-square- foot Space Shuttle Main Engine Processing Facility (SSMEPF) pose in front of a Space Shuttle Main Engine on display for the ceremony. From left, they are Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; John Plowden, vice president of Rocketdyne; Donald R. McMonagle, manager of Launch Integration; U.S. Congressman Dave Weldon; KSC Center Director Roy D. Bridges Jr.; Wade Ivey of Ivey Construction, Inc.; and Robert B. Sieck, director of Shuttle Processing. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  9. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    KSC Center Director Roy D. Bridges Jr. and U.S. Congressman Dave Weldon (holding scissors) cut the ribbon at a ceremony on July 6 to open KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF). Joining in the ribbon cutting are (left) Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; Marvin L. Jones, director of Installation Operations; Donald R. McMonagle, manager of Launch Integration; (right) Wade Ivey of Ivey Construction, Inc.; Robert B. Sieck, director of Shuttle Processing; and John Plowden, vice president of Rocketdyne. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  10. KSC-98pc915

    NASA Image and Video Library

    1998-08-13

    KENNEDY SPACE CENTER, FLA. -- Painters are suspended on platforms from the top of the 525-foot-high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag and NASA logo. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet, and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The previous Bicentennial Emblem on the right side of the VAB doors is being replaced by the NASA logo, honoring NASA’s 40th anniversary (in October). The logo will cover an area 110 feet by 132 feet, or about 12,300 square feet. The painting platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. Work is expected to be completed in mid-September

  11. KSC-2009-5322

    NASA Image and Video Library

    2009-10-06

    CAPE CANAVERAL, Fla. – Workers supervise the move of space shuttle Atlantis from its hangar, Orbiter Processing Facility 1, to the Vehicle Assembly Building at NASA’s Kennedy Space Center in Florida. The rollover began about 7 a.m. EDT and was complete at 8:25 a.m. when Atlantis was towed into the VAB's transfer aisle. Next, Atlantis will be lifted over a transom and lowered into the VAB's high bay 1, where it will be attached to its external fuel tank and solid rocket boosters. Rollout of the shuttle stack to Kennedy’s Launch Pad 39A, a significant milestone in launch processing activities, is planned for Oct. 13. Liftoff of Atlantis on its STS-129 mission to the International Space Station is targeted for 4:04 p.m. EST during a 10-minute launch window on Nov. 12. For information on the STS-129 mission and crew, visit http://www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts129/index.html. Photo credit: NASA/Jack Pfaller

  12. KSC-2010-5887

    NASA Image and Video Library

    2010-12-21

    CAPE CANAVERAL, Fla. -- Space shuttle Discovery awaits its move, called rollback, from Launch Pad 39A to the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. Rollback was scheduled for 12:30 a.m., but was postponed until 10 p.m. so technicians could resolve an issue with a leveling system on the crawler-transporter. Once inside the VAB, Discovery's external fuel tank will be examined and foam reapplied where 89 sensors were installed on the tank's aluminum skin for an instrumented tanking test on Dec. 17. The sensors were used to measure changes in the tank as super-cold propellants were pumped in and drained out. Data and analysis from the test will be used to determine what caused the tops of two, 21-foot-long support beams, called stringers, on the outside of the intertank to crack during fueling on Nov. 5. Discovery's next launch opportunity is no earlier than Feb. 3, 2011. For more information on STS-133, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Kim Shiflett

  13. KSC-2010-5888

    NASA Image and Video Library

    2010-12-21

    CAPE CANAVERAL, Fla. -- Space shuttle Discovery awaits its move, called rollback, from Launch Pad 39A to the Vehicle Assembly Building (VAB) at NASA's Kennedy Space Center in Florida. Rollback was scheduled for 12:30 a.m., but was postponed until 10 p.m. so technicians could resolve an issue with a leveling system on the crawler-transporter. Once inside the VAB, Discovery's external fuel tank will be examined and foam reapplied where 89 sensors were installed on the tank's aluminum skin for an instrumented tanking test on Dec. 17. The sensors were used to measure changes in the tank as super-cold propellants were pumped in and drained out. Data and analysis from the test will be used to determine what caused the tops of two, 21-foot-long support beams, called stringers, on the outside of the intertank to crack during fueling on Nov. 5. Discovery's next launch opportunity is no earlier than Feb. 3, 2011. For more information on STS-133, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Kim Shiflett

  14. KSC-98pc1044

    NASA Image and Video Library

    1998-08-06

    In this aerial view the Crawler Transporter Maintenance Building (center) sits between two crawler transporters. The KSC crawlers are the largest tracked vehicles known. Once used to move assembled Apollo/Saturn from the VAB to the launch pad, they are now used for transporting Shuttle vehicles. They move the Mobile Launcher Platform into the Vehicle Assembly Building and then to the Launch Pad with an assembled space vehicle. Maximum speed is 1.6 km (one mile) per hour loaded, about 3.2 km (2 miles) per hour unloaded. Launch Pad to VAB trip time with the Mobile Launch Platform is about 5 hours. The crawler burns 568 liters (150 gallons) of diesel oil per mile. KSC's two crawlers have accumulated 1,243 miles since 1977. Including the Apollo years, the transporters have racked up 2,526 miles, about the same distance as a one-way trip from KSC to Los Angeles by interstate highway or a round trip between KSC and New York City

  15. KENNEDY SPACE CENTER, FLA. - Workers ride the rails along with a container enclosing a segment of a solid rocket booster being moved to the main track. Several segments are being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

    NASA Image and Video Library

    2004-01-30

    KENNEDY SPACE CENTER, FLA. - Workers ride the rails along with a container enclosing a segment of a solid rocket booster being moved to the main track. Several segments are being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

  16. KENNEDY SPACE CENTER, FLA. - The red NASA engine backs up with its cargo of containers in order to change tracks. The containers enclose segments of a solid rocket booster being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

    NASA Image and Video Library

    2004-01-30

    KENNEDY SPACE CENTER, FLA. - The red NASA engine backs up with its cargo of containers in order to change tracks. The containers enclose segments of a solid rocket booster being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

  17. KENNEDY SPACE CENTER, FLA. - The red NASA engine moves forward past the Vehicle Assembly Building with its cargo of containers enclosing segments of a solid rocket booster being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

    NASA Image and Video Library

    2004-01-30

    KENNEDY SPACE CENTER, FLA. - The red NASA engine moves forward past the Vehicle Assembly Building with its cargo of containers enclosing segments of a solid rocket booster being returned to Utah for testing. The segments were part of the STS-114 stack. It is the first time actual flight segments that had been stacked for flight in the VAB are being returned for testing. They will undergo firing, which will enable inspectors to check the viability of the solid and verify the life expectancy for stacked segments.

  18. KENNEDY SPACE CENTER, FLA. - Workers accompany the orbiter Atlantis as it is towed back to the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

    NASA Image and Video Library

    2003-12-16

    KENNEDY SPACE CENTER, FLA. - Workers accompany the orbiter Atlantis as it is towed back to the Orbiter Processing Facility after spending 10 days in the Vehicle Assembly Building. The hiatus in the VAB allowed work to be performed in the OPF that can only be accomplished while the bay is empty. Work included annual validation of the bay's cranes, work platforms, lifting mechanisms and jack stands. Work resumes to prepare Atlantis for launch in September 2004 on the first return-to-flight mission, STS-114.

  19. KSC-2012-4317

    NASA Image and Video Library

    2012-08-06

    CAPE CANAVERAL, Fla. – Mockup components of an Orion spacecraft are laid out in the transfer aisle of the Vehicle Assembly Building, or VAB, at NASA's Kennedy Space Center in Florida. In the foreground is the Launch Abort System. In the background is the Orion capsule model on top of a service module simulator. Orion is the exploration spacecraft designed to carry crews to space beyond low Earth orbit. It will provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities. The first uncrewed test flight of the Orion is scheduled to launch in 2014 atop a Delta IV rocket and in 2017 on a Space Launch System rocket. The Orion mockup is exact in details on the outside, but mostly empty on the inside except for four mockup astronaut seats and hatch. The work in the VAB is crucial to making sure the designs are accurate. For more information, visit http://www.nasa.gov/orion Photo credit: NASA/ Dmitri Gerondidakis

  20. Aerial view of the KSC crawler transporters

    NASA Technical Reports Server (NTRS)

    1998-01-01

    In this aerial view the Crawler Transporter Maintenance Building (center) sits between two crawler transporters. The KSC crawlers are the largest tracked vehicles known. Once used to move assembled Apollo/Saturn from the VAB to the launch pad, they are now used for transporting Shuttle vehicles. They move the Mobile Launcher Platform into the Vehicle Assembly Building and then to the Launch Pad with an assembled space vehicle. Maximum speed is 1.6 km (one mile) per hour loaded, about 3.2 km (2 miles) per hour unloaded. Launch Pad to VAB trip time with the Mobile Launch Platform is about 5 hours. The crawler burns 568 liters (150 gallons) of diesel oil per mile. KSC's two crawlers have accumulated 1,243 miles since 1977. Including the Apollo years, the transporters have racked up 2,526 miles, about the same distance as a one-way trip from KSC to Los Angeles by interstate highway or a round trip between KSC and New York City.

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