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Sample records for bhupendra singh vivek

  1. Observatories of Sawai Jai Singh II

    NASA Astrophysics Data System (ADS)

    Johnson-Roehr, Susan N.

    Sawai Jai Singh II, Maharaja of Amber and Jaipur, constructed five observatories in the second quarter of the eighteenth century in the north Indian cities of Shahjahanabad (Delhi), Jaipur, Ujjain, Mathura, and Varanasi. Believing the accuracy of his naked-eye observations would improve with larger, more stable instruments, Jai Singh reengineered common brass instruments using stone construction methods. His applied ingenuity led to the invention of several outsize masonry instruments, the majority of which were used to determine the coordinates of celestial objects with reference to the local horizon. During Jai Singh's lifetime, the observatories were used to make observations in order to update existing ephemerides such as the Zīj-i Ulugh Begī. Jai Singh established communications with European astronomers through a number of Jesuits living and working in India. In addition to dispatching ambassadorial parties to Portugal, he invited French and Bavarian Jesuits to visit and make use of the observatories in Shahjahanabad and Jaipur. The observatories were abandoned after Jai Singh's death in 1743 CE. The Mathura observatory was disassembled completely before 1857. The instruments at the remaining observatories were restored extensively during the nineteenth and twentieth centuries.

  2. Award for Distinguished Early Career Contributions to Psychology in the Public Interest: Anneliese A. Singh.

    PubMed

    2016-11-01

    The APA Awards for Distinguished Contributions to Psychology in the Public Interest recognize persons who have advanced psychology as a science and/or profession by a single extraordinary achievement or a lifetime of outstanding contributions in the public interest. The 2016 corecipient of the Award for Distinguished Early Career Contributions to Psychology in the Public Interest is Anneliese A. Singh. Dr. Singh's scholarship "has promoted major advancements in LBGT studies and intersectionality of multiple identities." Singh's award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record

  3. Neurovirology: neurotropic viruses and the brain. Interview with Sunit K Singh by Hannah Branch.

    PubMed

    Singh, Sunit K

    2013-08-01

    Sunit K Singh speaks to Hannah Branch, Commissioning Editor Sunit K Singh obtained a Bachelor's degree from GB Pant University of Agriculture and Technology (India) followed by his Master's degree from the Central Institute of Fisheries Education (India). Upon the completion of his Master's degree, Singh moved to the University of Wuerzburg (Germany) to complete his PhD degree in the field of Molecular Infection Biology. Subsequently, he undertook his postdoctoral training at Yale University School of Medicine (CT, USA) and at the University of California Davis Medical Center (CA, USA). Singh has also been visiting faculty at the Albert Einstein College of Medicine (NY, USA), Department of Pathology and Immunology, University of Geneva (Switzerland) and the Institute of Parasitology (Czech Republic). At present, he is a permanent member of faculty in the Section of Infectious Diseases and Immunobiology Centre for Cellular and Molecular Biology (CCMB; India) and is leading a research group in the area of neurovirology there. Singh has been an author of a number of papers published in peer-reviewed journals, and has been honored with several awards, including the Skinner Memorial Award, Young Scientist Award, Travel Grant Award and the NIH-Fogarty Fellowship. In addition, he is a valued editorial board member of several journals, including Future Microbiology.

  4. Print and Electronic Resources: Usage Statistics at Guru Gobind Singh Indraprastha University Library

    ERIC Educational Resources Information Center

    Kapoor, Kanta

    2010-01-01

    Purpose: The purpose of this paper is to quantify the use of electronic journals in comparison with the print collections in the Guru Gobind Singh Indraprastha University Library. Design/methodology/approach: A detailed analysis was made of the use of lending services, the Xerox facility and usage of electronic journals such as Science Direct,…

  5. The Role of Contrast in the Perception of Achromatic Transparency: Comment on Singh and Anderson (2002) and Anderson (2003)

    ERIC Educational Resources Information Center

    Albert, Marc K.

    2008-01-01

    M. Singh and B. L. Anderson proposed a perceptual theory of achromatic transparency in which the perceived transmittance of a perceived transparent filter is determined by the ratio of the Michelson contrast seen in the region of transparency to that of the background seen directly. Subsequently, B. L. Anderson, M. Singh, and J. Meng proposed that…

  6. The nano man from India: in celebration of the 60th birthday of Dr. Hari Singh Nalwa.

    PubMed

    Schmidt, Werner F; Singh, Surya

    2014-01-01

    This article is devoted to the 60th birthday of Dr. Hari Singh Nalwa and outlines his outstanding contributions, distinguished scientific career and business accomplishments to date. The January and February 2014 issues of the Journal of Nanoscience and Nanotechnology, dedicated to Dr. Hari Singh Nalwa on the occasion of his 60th birthday, provide its readers 134 state-of-the-art review articles contributed by leading experts from around the world focusing on a wide range of nanotechnology-related research areas.

  7. Applications of Singh-Rajput Mes in Recall Operations of Quantum Associative Memory for a Two- Qubit System

    NASA Astrophysics Data System (ADS)

    Singh, Manu Pratap; Rajput, B. S.

    2016-03-01

    Recall operations of quantum associative memory (QuAM) have been conducted separately through evolutionary as well as non-evolutionary processes in terms of unitary and non- unitary operators respectively by separately choosing our recently derived maximally entangled states (Singh-Rajput MES) and Bell's MES as memory states for various queries and it has been shown that in each case the choices of Singh-Rajput MES as valid memory states are much more suitable than those of Bell's MES. it has been demonstrated that in both the types of recall processes the first and the fourth states of Singh-Rajput MES are most suitable choices as memory states for the queries `11' and `00' respectively while none of the Bell's MES is a suitable choice as valid memory state in these recall processes. It has been demonstrated that all the four states of Singh-Rajput MES are suitable choice as valid memory states for the queries `1?', `?1', `?0' and `0?' while none of the Bell's MES is suitable choice as the valid memory state for these queries also.

  8. Processes of Quantum Associative Memory (QuAM) Through New Maximally Entangled States (Singh-Rajput MES)

    NASA Astrophysics Data System (ADS)

    Singh, Manu Pratap; Rajput, B. S.

    2016-07-01

    Using Singh-Rajput MES as memory states in the evolutionary process of pattern storage and the non-evolutionary process of pattern recall (the two fundamental constituents of QuAM), the suitability and superiority of these MES over Bell's MES have been demonstrated in both these processes. It has been shown that, under the operations of all the possible memorization operators for a two-qubit system, the first two states of Singh-Rajput MES are useful for storing the pattern |11> and the last two of these MES are useful in storing the pattern |10> while Bell's MES are not much suitable as memory states in a valid memorization process. The recall operations have also been conducted by separately choosing Singh-Rajput MES and Bell's MES as memory states for possible various queries and it has been shown that in each case the choices of Singh-Rajput MES as valid memory states are much more suitable than those of Bell's MES.

  9. Other Aspects of Sutherland and Singh's Take on Learned Helplessness and Students with Emotional or Behavioral Disorders

    ERIC Educational Resources Information Center

    Kavale, Kenneth A.; Mostert, Mark P.

    2004-01-01

    Sutherland and Singh (2004) focus on the relationship between students' inappropriate behaviors and academic failure, articulating how this relationship may be mediated by learned helplessness in a reciprocally negative reinforcing cycle. In responding to their work, the authors suggest a thread of disciplined inquiry and contextual framework for…

  10. Epidemiology of Eimeria and associated risk factors in cattle of district Toba Tek Singh, Pakistan.

    PubMed

    Rehman, Tauseef Ur; Khan, Muhammad Nisar; Sajid, Muhammad Sohail; Abbas, Rao Zahid; Arshad, Muhammad; Iqbal, Zafar; Iqbal, Asif

    2011-05-01

    A cross-sectional study was carried out to determine the prevalence, species characterization, and associated risk factors with Eimeria of cattle of district Toba Tek Singh from April, 2009 to March, 2010. Of the total 584 fecal samples examined for Eimeria, 275 (47.09%) were found infected with six species of Eimeria. Among the identified species of Eimeria, Eimeria bovis was found to be the highest prevalent species (52.36%), followed in order by Eimeria zuernii, Eimeria canadensis, Eimeria ellipsoidalis, Eimeria alabamensis, and Eimeria cylindrica with prevalence of 48.27%, 34.83%, 29.31%, 24.14%, and 8.62% respectively. Peak prevalence was observed in August. Cattle were infected more frequently during rainy (60.32%) and post-rainy seasons (59.25%). Calves had significantly higher prevalence (P<0.05) of Eimeria than adults while higher prevalence of Eimeria was observed in female cattle. Among management and husbandry practices, feeding system, watering system, housing system, floor type, and herd size strongly influenced the prevalence of Eimeria in cattle. Coccidiosis was more prevalent in ground feeding system, pond-watered animals, closed housing system, and non-cemented floor type (P<0.05) as compared to trough feeding system, tap watered animals, open housing system, and partially cemented floor types, respectively. Breed and body condition of animals were not found risk factors (P>0.05) influencing prevalence of Eimeria.

  11. Two new species of Cylicospirura Vevers, 1922 (Nematoda: Spirocercidae) from carnivores in southern Africa, with validation of the related genera Gastronodus Singh, 1934 and Skrjabinocercina Matschulsky, 1952.

    PubMed

    Junker, Kerstin; Lane, Emily P; McRee, Anna E; Foggin, Chris; van Dyk, D Schalk; Mutafchiev, Yasen

    2013-09-01

    Two new species of Cylicospirura Vevers, 1922 are described from carnivores from southern Africa. Cylicospirura crocutae Junker et Mutafchiev sp. n. from Crocuta crocuta (Erxleben) in Zimbabwe is distinguished from its congeners by combinations of characters, including the presence of four cephalic and four external labial papillae, while internal labial papillae were not distinct, the presence of groups of small accessory teeth between the six large tricuspid teeth, the fifth and the sixth pairs of the caudal papillae being equidistant from the cloaca, and a large ratio of length of the muscular oesophagus to that of the glandular oesophagus. Cylicospirura pardalis Junker et Mutafchiev sp. n. from Panthera pardus (Linnaeus) in the Republic of South Africa is characterized by having tricuspid teeth with large, claw-like, abaxial cusps, four cephalic and six internal labial papillae. Based on the number of caudal papillae and the position of the vulva, the subgenera Gastronodus Singh, 1934 and Skrjabinocercina Matschulsky, 1952 are re-elevated to generic rank. Amended diagnoses are proposed for the genera Cylicospirura, Gastronodus and Skrjabinocercina. Petrowospirura lyncis Matschulsky, 1952 is recognized as valid and, together with P. petrowi Sadykhov, 1957 and P. barusi Arya, 1979, is transferred to Cylicospirura as C. lyncis (Matschulsky, 1952) Junker et Mutafchiev comb. n., C. petrowi (Sadykhov, 1957) Junker et Mutafchiev comb. n. and C. barusi (Arya, 1979) Junker et Mutafchiev comb. n., respectively.

  12. Comments on the paper “Temperature dependence of bulk modulus and second-order elastic constants” by P.P. Singh and M. Kumar [Physica B 344 (2004) 41

    NASA Astrophysics Data System (ADS)

    Singh, K. S.

    2005-05-01

    Singh and Kumar have questioned the validity of the Mie-Grüneisen equation using an incorrect formulation. The Suzuki equation for thermal expansivity has been expressed by them in terms of thermal pressure using a wrong definition. The formulations already reported in the literature have been rediscovered by them and redesignated as the Kumar formulation. In the present communication we have reinforced the validity of the Mie-Grüneisen EOS using the correct definition of thermal pressure in the Suzuki formulation.

  13. Note on: 'EMDPLER: A F77 program for modeling the EM response of dipolar sources over the non-magnetic layer earth models' by N.P. Singh and T. Mogi, Computers & Geosciences 36 (2010) 430-440

    NASA Astrophysics Data System (ADS)

    Jamie, Majid; Mirzaei, Saeid; Mirzaei, Mahmoud

    2017-01-01

    In this paper some mistakes arising in Singh and Mogi (2010) that are: (1) wrong formulation of the intrinsic impedance of the layers of an N-layered earth (Zi) and reflection coefficient of the EM wave in TM-mode (rTM), (2) using wrong and the very same algorithms for computing reflection coefficients of the EM wave in both the TE- and the TM-mode (rTE and rTM) and (3) using flawed algorithms for computing phase and normalized phase values, relating to electric and magnetic components of the EM wave, are noted and corrected form of these mistakes are presented. Moreover, in order to illustrate how these mistakes can affect forward modeling results different two- and three-layered earth models, the same as the models used in Singh and Mogi (2010), are chosen; afterwards EMDPLER and corrected version of this program, presented in this paper titled "EMDPLER_Corr", are conducted on these models and real and imaginary parts of Hz and Hy components of the magnetic field intensity, their normalized amplitudes (|Hz /Hz0 |and|Hy /Hy0 |) and the corresponding normalized phases are computed, plotted versus frequency and compared with each other.

  14. Comment on 'A reinterpretation of the linear heat flow and heat production relationship for the exponential model of the heat production in the crust' by R.N. Singh & J.G. Negi.

    USGS Publications Warehouse

    Lachenbruch, A.H.

    1980-01-01

    In their recent paper, Singh & Negi, (This journal, 57, 741-744) contend that if thd slope of the empirical linear relation between heat flow and heat production is interpreted as the decay-length of an exponential depth-distribution of sources, a discrepancy rises, whereas if it is interpreted as the depth of a step distribution, it does not. I should like to point out that their discrepancy follows from their arbitrary assumption of one of a range of physical possibilities unconstrained by the observations; with an equally valid alternate assumption (Lachenbruch 1970) the discrepancy disappears. In any case such discrepancies are probably minor compared to physical difficulties that arise from the step model, and to uncertainties introduced by other assumptions in any simple model.-Author

  15. Note on: 'EMLCLLER-A program for computing the EM response of a large loop source over a layered earth model' by N.P. Singh and T. Mogi, Computers & Geosciences 29 (2003) 1301-1307

    NASA Astrophysics Data System (ADS)

    Jamie, Majid

    2016-11-01

    Singh and Mogi (2003) presented a forward modeling (FWD) program, coded in FORTRAN 77 called "EMLCLLER", which is capable of computing the frequency-domain electromagnetic (EM) response of a large circular loop, in terms of vertical magnetic component (Hz), over 1D layer earth models; computations at this program could be performed by assuming variable transmitter-receiver configurations and incorporating both conduction and displacement currents into computations. Integral equations at this program are computed through digital linear filters based on the Hankel transforms together with analytic solutions based on hyper-geometric functions. Despite capabilities of EMLCLLER, there are some mistakes at this program that make its FWD results unreliable. The mistakes in EMLCLLER arise in using wrong algorithm for computing reflection coefficient of the EM wave in TE-mode (rTE), and using flawed algorithms for computing phase and normalized phase values relating to Hz; in this paper corrected form of these mistakes are presented. Moreover, in order to illustrate how these mistakes can affect FWD results, EMLCLLER and corrected version of this program presented in this paper titled "EMLCLLER_Corr" are conducted on different two- and three-layered earth models; afterwards their FWD results in terms of real and imaginary parts of Hz, its normalized amplitude, and the corresponding normalized phase curves are plotted versus frequency and compared to each other. In addition, in Singh and Mogi (2003) extra derivations for computing radial component of the magnetic field (Hr) and angular component of the electric field (Eϕ) are also presented where the numerical solution presented for Hr is incorrect; in this paper the correct numerical solution for this derivation is also presented.

  16. Comment on “Geochemistry of buried river sediments from Ghaggar Plains, NW India: Multi-proxy records of variations in provenance, paleoclimate, and paleovegetation patterns in the late quaternary” by Ajit Singh, Debajyoti Paul, Rajiv Sinha, Kristina J. Thomsen, Sanjeev Gupta

    USGS Publications Warehouse

    Clift, Peter D.; Giosan, Liviu; East, Amy E.

    2016-01-01

    Singh et al. (2016) published a geochemical record of sediment compositions from the flood plain of the Ghaggar River in western India and use the changing provenance, particularly as traced by Nd isotope composition, to reconstruct how erosion patterns have changed over the past 100 k.y. In doing so they propose a link between climate change and erosion, and they argue for more erosion from the Higher Himalaya during warmer interglacial periods and more from the Lesser Himalaya during glacial intervals. While we support the concept of erosion patterns being climatically modulated we here take the opportunity to compare the data presented by Singh et al. (2016) to relevant published records within the region greater Ghaggar region and to open a balanced discussion on how climate and erosion are coupled in the western Himalaya.

  17. A Model to Predict Duration of Ventilation and 30-Day Mortality in Patients with Traumatic Injuries

    DTIC Science & Technology

    2014-12-02

    Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per...2 19a. NAME OF RESPONSIBLE PERSON a. REPORT unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98...383 PATTERN OF HOSPITAL ADMISSIONS AND OUTCOME OF ACUTE ALUMINIUM PHOSPHIDE POISONING IN AN INDIAN ICU RANVIR SINGH1, diptimala agrawal2, vivek

  18. Philosophizing cannot substitute for experimentation: comment on Hoffman, Singh & Prakash

    PubMed Central

    Pizlo, Zygmunt

    2015-01-01

    The perception of 3D shape must be excluded from Hoffman et al., “interface theory” primarily because shape is characterized by its symmetries. When these symmetries are used as a priori constraints, 3D shapes are always recovered from 2D retinal images veridically. These facts make it clear that 3D shape perception is completely different from, as well as more important than, all other perceptions because the veridicality of our perception of 3D shapes (and 3D scenes) accounts for our successful adaptation to the natural environment. PMID:26384989

  19. VizieR Online Data Catalog: Ultra steep spectrum radio sources (Singh+, 2014)

    NASA Astrophysics Data System (ADS)

    Singh, V.; Beelen, A.; Wadadekar, Y.; Sirothia, S.; Ishwara-Chandra, C. H.; Basu, A.; Omont, A.; McAlpine, K.; Ivison, R. J.; Oliver, S.; Farrah, D.; Lacy, M.

    2014-11-01

    We obtained 325 MHz GMRT observations of the XMM-LSS field over sky area of ~12deg2 with synthesized beamsize ~10.2"x7.9". In the mosaiced 325MHz GMRT image the average noise rms is ~160uJy, while in the central region the average noise-rms reaches to ~120uJy. Our 325MHz observations are one of the deepest low-frequency surveys over such a wide sky area and detect ~2553/3304 radio sources at >=5.0σ with noise rms cut-off <=200/300uJy. (1 data file).

  20. Raja Sawai Jai Singh II: An 18th Century Medieval Astronomer

    ERIC Educational Resources Information Center

    Blanpied, William A.

    1975-01-01

    Offers a description of the instrumentation and methods utilized in this attempt at naked eye astronomy one century after the invention of the telescope. Also examines the motives which resulted in the implementation of an antiquated mode of observation. (Author/CP)

  1. New combination bronchodilators for chronic obstructive pulmonary disease: current evidence and future perspectives Dave Singh

    PubMed Central

    Singh, Dave

    2015-01-01

    Fixed dose combination (FDC) dual bronchodilators that co-administer a long acting β2-adrenoceptor agonist (LABA) and a long acting muscarinic antagonist (LAMA) are a new class of inhaled treatment for chronic obstructive pulmonary disease (COPD). This review focuses on the clinical evidence for the benefit of LABA/LAMA FDCs compared with monocomponent treatments, and also compared with active comparators that are widely used for the treatment of COPD, namely tiotropium and salmeterol-fluticasone. Novel FDC dual bronchodilators include QVA149 and umeclidinium/vilanterol (UMEC/VI). Long term clinical trials show that QVA149 and UMEC/VI are superior to monocomponent therapy in terms of trough forced expiratory volume in 1 s (FEV1), although the FEV1 improvement was limited to approximately 80–90% of the added monocomponent values. This suggests that the effect of combining a LABA and a LAMA is not fully additive. LABA/LAMA FDC were associated with the largest mean changes in symptoms and health status that were above the minimal clinically important difference, in contrast to the monocomponents. Furthermore, these LABA/LAMA FDCs demonstrated superiority over the active comparators tiotropium and salmeterol-fluticasone in terms of trough FEV1 and patient-reported outcomes. LABA/LAMA FDCs offer a simplified means of maximizing bronchodilation for COPD patients, with the improvements in lung function being mirrored by benefits in terms of symptoms and exacerbations. The use of LABA/LAMA FDCs in clinical practice is set to grow and further studies are needed to define their optimal place in treatment guidelines. PMID:25377687

  2. Parts, Materials, and Processes Control Program for Expendable Launch Vehicles

    DTIC Science & Technology

    2015-05-21

    Kysela United Launch Alliance george.f.kysela@ulalaunch.c om Brian Julius SpaceX Brian.Julius@spacex.com Vivek Hazari SpaceX Vivek.Hazari@spacex.com... SpaceX Hans.Koenigsmann@ spacex . com Paul R. Croll Institute of Electrical and Electronics Engineers pcroll@computer.org Steve Henry Northrop Grumman

  3. Contribution to our knowledge of the whitefly genus Aleuroclava Singh (Hemiptera: Aleyrodidae) in China, including Taiwan and Hong Kong, with descriptions of two new species.

    PubMed

    Wang, Ji-Rui; Du, Yu-Zhou

    2016-07-15

    Two new whitefly species, Aleuroclava sterculiae sp. nov., collected from Sterculia nobilis (Malvales: Sterculiaceae) of Qingxiu hill park (Guangxi, China), and Aleuroclava rosae sp. nov., collected from Stranvaesia sp. (Rosales: Rosaceae) of Maoer Mountain (Guangxi, China), are described with morphology, line illustrations, photographs and scanning electron microscope (SEM) images. In addition, two other whitefly species, Aleuroclava lefroyi (Sundararaj & David) and Aleuroclava manii (David), are reported as new to the fauna of China, and are discussed. An identification key to Aleuroclava species known from Mainland China, Taiwan and Hong Kong is provided. The specimens are deposited in the Insect Collection of Yangzhou University (YZU).

  4. Addenda to Allied Medical Publication 8, NATO Planning Guide for the Estimation of Chemical, Biological, Radiological, and Nuclear (CBRN) Casualties (AMedP-8(C)) to Consider the Impact of Medical Treatment on Casualty Estimation

    DTIC Science & Technology

    2013-05-01

    Osterholm, Tara O’Toole, Gerald Parker, Trish M. Perl, Philip K. Russell , David L. Swerdlow, and Kevin Tonat. “Botulinum Toxin as a Biological Weapon...DeAngelis, Louise Cain, Barbara Wallace , and Nellie Dumas. “Laboratory-Acquired Brucellosis.” Emerging Infectious Diseases 10, no. 10 (2004): 1848–50...Amari, Alfred M. Sciuto, Richard K. Gordon, Bhupendra P. Doctor, and Madhusoodana P. Nambiar. “Post-Exposure Treatment with Nasal Atropine Methyl

  5. Systemic Administration of the Potential Countermeasure Huperzine Reversibly Inhibits Central and Peripheral Acetylcholinesterase Activity Without Adverse Cognitive-Behavioral Effects

    DTIC Science & Technology

    2010-01-01

    Medical Research Institute of Chemical Defense ATTN: MCMR-CDT-N 3100 Ricketts Point Road Aberdeen Proving Ground, MD 21010-5400 USAMRICD...P10-013 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) US Army Medical Research Institute of Aberdeen...Ashima Saxena b, Bhupendra P. Doctor b, Andrew J. Bonvillain a, Matthew G. Clark a a United States Army Medical Research Institute of Chemical

  6. 77 FR 52381 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ... Singh Mr. Singh, 27, has had amblyopia in his left eye since childhood. The visual acuity in his right... drive ``semi'' vehicles.'' Mr. Singh reported that he has driven tractor-trailer combinations for...

  7. Comment on "Atomic structure calculations and identification of EUV and SXR spectral lines in Sr XXX" by A. Goyal, I. Khatri, S. Aggarwal, A.K. Singh, M. Mohan [J Quant Spectrosc Radiat Transf 2015;161:157

    NASA Astrophysics Data System (ADS)

    Aggarwal, Kanti M.

    2015-11-01

    Recently, Goyal et al. [1] reported energies and lifetimes (τ) for the lowest 113 levels of the 2s22p5, 2s2p6, 2s22p43ℓ, 2s2p53ℓ and 2p63ℓ configurations of F-like Sr XXX. For the calculations they adopted the multi-configuration Dirac-Fock (MCDF) and the flexible atomic code (FAC). Additionally, they also listed radiative rates (A- values), oscillator strengths (f- values) and line strengths (S- values) for four types of transitions, namely electric dipole (E1), electric quadrupole (E2), magnetic dipole (M1) and magnetic quadrupole (M2), but only from the ground to the higher excited levels. However, there are two clear anomalies in their reported data. Firstly, the f-values listed from FAC in their Tables 3-6 are larger than from MCDF by a factor of two, for all transitions. This is because they have blindly listed the output from FAC without realising that, unlike MCDF, FAC lists ωf where ω is the statistical weight, and happens to be exactly 2 in the present case. Secondly, their lifetime for level 2 (2s22p51/2 o 2P) is incorrect. This is because the dominant contributing transition for this level is 1-2 M1 for which A=3.25×106 s-1, listed (correctly) in their Table 5, and this leads to τ=3.08×10-7 s, and not 1.54×10-7 s, as listed in their Table 1.

  8. A resolution honoring the Prime Minister of India, Dr. Manmohan Singh, for his service to the people of India and to the world, and welcoming the Prime Minister to the United States.

    THOMAS, 111th Congress

    Sen. Dodd, Christopher J. [D-CT

    2009-11-21

    11/21/2009 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S11976-11977; text as passed Senate: CR S11976-11977; text of measure as introduced: CR S11973) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  9. 78 FR 28236 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... Executive Blvd, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Sheo Singh, Ph.D... Executive Blvd., Rockville, MD 20852, (Telephone Conference Call). Contact Person: Sheo Singh,...

  10. Description of a new genus and three species of Encyrtidae (Hymenoptera: Chalcidoidea) from the Western Ghats of Karnataka, India.

    PubMed

    Singh, Sudhir; Devi, O K Rema; Srinivasa, Y B

    2014-06-10

    A new genus of Encyrtidae (Hymenoptera: Chalcidoidea), Noyesencyrtus Singh gen. nov. (type species N. brachyoculus Singh sp. nov.), associated with insects inhabiting fruiting bodies of wood-decaying fungi, and two new species, Psyllaephagus kundapurensis Singh sp. nov. and Ooencyrtus hayatii Singh sp. nov., are described from the Western Ghats of Karnataka, India.

  11. Education Policy and the Pursuit of Equality: Perspectives from South Africa

    ERIC Educational Resources Information Center

    Sayed, Yusuf; Vellanki, Vivek

    2013-01-01

    1994 is an important year in South African history. It brought about significant socio-political changes in an attempt to undo the unjust practices perpetuated during the apartheid regime. The apartheid government had severely impacted all spheres and institutions of society, including education. In this interview, Vivek Vellanki asks Doctor Yusuf…

  12. Safe, Multiphase Bounds Check Elimination in Java

    DTIC Science & Technology

    2010-01-28

    National Science Foundation under grants CCF-0846010, EIA-0117255, CCF-0702527, and CNS-0855247. References [1] Elvira Albert, Germán Puebla , and Manuel...Symbolic analysis for parallelizing compilers. PhD thesis, University of Illinois at Urbana -Champaign, Champaign, IL, USA, 1995. [29] Vivek Haldar

  13. Unlocking Shelves: Fostering a Culture of Reading and Inclusion through Open Libraries

    ERIC Educational Resources Information Center

    Mukunda, Usha; Vellanki, Vivek

    2016-01-01

    This article features a conversation between Usha Mukunda, who identifies herself as a librarian, and Vivek Vellanki, who is currently pursuing a doctoral degree in education. Mukunda has been successful in challenging the stereotypical image of the librarian as being serious, angry, and detached. Shortly after meeting her, one would likely be…

  14. 78 FR 1217 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ..., 6120 Executive Blvd., Rockville, MD 20852, (Telephone Conference Call). Contact Person: Sheo Singh, Ph...., Rockville, MD 20852. Contact Person: Sheo Singh, Ph.D., Scientific Review Officer, Scientific Review...

  15. The Design and Implementation of a Prototype Web-Portal for the Integrated Mobile Alerting System (IMAS)

    DTIC Science & Technology

    2006-06-01

    Thesis Advisor: Gurminder Singh Second Reader: Magdi Kamel THIS PAGE INTENTIONALLY LEFT...Gurminder Singh Thesis Advisor Magdi Kamel Second Reader Dan Boger Chairman, Department of Information Sciences iv

  16. 76 FR 3918 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Call). Contact Person: Sheo Singh, PhD, Scientific Review Officer, Scientific Review Branch, Division...). Contact Person: Sheo Singh, PhD, Scientific Review Officer, Scientific Review Branch, Division of...: Sheo Singh, PhD, Scientific Review Officer, Scientific Review Branch, Division of Extramural...

  17. 75 FR 18512 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ...., Rockville, MD 20852. (Virtual Meeting.) Contact Person: Sheo Singh, PhD, Scientific Review Officer... 20852. (Telephone Conference Call.) Contact Person: Sheo Singh, PhD, Scientific Review Officer...: Sheo Singh, PhD, Scientific Review Officer, Scientific Review Branch, Division of Extramural...

  18. Corrigendum to ''Note on: 'EMDPLER: A F77 program for modeling the EM response of dipolar sources over the non-magnetic layer earth models' by N.P. Singh and T. Mogi, Computers & Geosciences 36 (2010) 430-440'' [Computers & Geosciences 98 (2017) 94-106

    NASA Astrophysics Data System (ADS)

    Jamie, Majid; Mirzaei, Saeid; Mirzaei, Mahmoud

    2017-03-01

    The authors regret that some of the figures published at Jamie et al. (2017) contain error and/or their captions are not well clear (e.g. the receivers' exact locations have not been mentioned); hereby we present correct and more expressive alternatives to these figures. The authors would like to apologize for any inconvenience caused.

  19. Development and Simulation Studies of a Novel Electromagnetics Code

    DTIC Science & Technology

    2011-10-20

    Vivek Krishna, who received his M.S. degree in computer science, Abhijeet Kodgire who was a computer science student, Adarsh Yoga , who received his M.S...graduate students, namely Adarsh Yoga and Abhijeet Kodgire. Mr. Yoga was responsible for benchmarking our dispersion free methods against a finite...computer science department were supported by this grant, Adarsh Yoga and Abhijeet Kodgire. In September 2010, Mr. Kodgire’s support ended on this

  20. 25 Point Implementation Plan to Reform Federal information Technology Management

    DTIC Science & Technology

    2010-12-09

    25 POINT IMPLEMENTATION PLAN TO REFORM FEDERAL INFORMATION TECHNOLOGY MANAGEMENT Vivek Kundra U.S. Chief Information Officer DECEMBER 9, 2 010... information Technology Management 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f...RefoRm fedeRal infoRmaTion TeChnology managemenT ii★ ★ C2 . Align the Budget Process with the Technology Cycle

  1. A Strategic Approach to Network Defense: Framing the Cloud

    DTIC Science & Technology

    2011-03-10

    U.S. Chief Information Officer Vivek Kundra, 25 Point Implementation Plan to Reform Federal Information Technology Management (Washington, DC: The...3 Ibid., 71. 4 U.S. Chief Information Officer, 25 Point Implementation Plan to Reform Federal Information Technology Management , 5. 5 Ibid., 5. 6...Ibid., 73. 56 U.S. Chief Information Officer, 25 Point Implementation Plan to Reform Federal Information Technology Management , 7. 57 Ibid. 58 Ibid

  2. Hypohidrotic ectodermal dysplasia: a felicitous approach to esthetic and prosthetic management.

    PubMed

    Singh, Tapan; Singh, Ronauk; Singh, Gurendra Pal; Singh, Jitender Pal

    2013-05-01

    Ectodermal dysplasia is a hereditary disease characterized by congenital dysplasia of one or more ectodermal structure and other accessory appendages. The oral manifestations are anodontia and poor bony foundation which impairs both esthetic as well as the masticatory function. The prosthodontic management of patients with such dysplastic condition necessitates a multidisciplinary approach. This case report describes the prosthodontic oral rehabilitation of a 16 years old female pediatric patient with ectodermal dysplasia. How to cite this article: Singh T, Singh R, Singh GP, Singh JP. Hypohidrotic Ectodermal Dysplasia: A Felicitous Approach to Esthetic and Prosthetic Management. Int J Clin Pediatr Dent 2013;6(2):140-145.

  3. 76 FR 44330 - Ocean Transportation Intermediary License Applicants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ..., Seattle, WA 98188, Officers: Charles K. Behrens, President, (Qualifying Individual), Todd L. Halverson..., Jamaica, NY 11434, Officers: Harjinder P. Singh, President/Chief Executive Manager, (Qualifying...

  4. Optimizing the Mobilization of Wireless Communications Systems for Disaster Response Efforts

    DTIC Science & Technology

    2015-09-01

    the 9/11 terrorist attack and the 2010 Deepwater Horizon oil spill (Antillon, 2012; Hwee, Calvin, Singh, & McKenzie , 2007; Lancaster, 2005). The...Hwee, L. M., Calvin, N., Singh, G., & Mckenzie , S. (2007). An integrated architecture to the support hastily formed network. Master’s thesis, Naval

  5. Polymers and Liquid Crystals Symposium held in Boston, Massachusetts on August 19-23, 2007 (Abstracts)

    DTIC Science & Technology

    2007-12-20

    SCLCPs Coleen Pugh, Anirudha Singh 4:35 PM 5 Morphology of side chain liquid crystalline block copolymers: Influence of liquid crystal content Eric...Anirudha Singh, Coleen Pugh 472 Preparation of supramolecular discotic liquid crystals containing hydrogen bonds Seung Jun Lee, Mikyung You, Jin Woo Kim

  6. Natural Decompositions of Perceived Transparency: Reply to Albert (2008)

    ERIC Educational Resources Information Center

    Anderson, Barton L.; Singh, Manish; O'Vari, Judit

    2008-01-01

    In M. Singh and B. L. Anderson, the authors proposed a model based on ratios of Michelson contrasts to explain how human observers quantitatively scale the perceived opacity of transparent surfaces. In subsequent work by B. L. Anderson, M. Singh, & J. Meng, the authors found that this model failed to generalize to other contexts and replaced it…

  7. Further Analysis of Picture Interference when Teaching Word Recognition to Children with Autism

    ERIC Educational Resources Information Center

    Dittlinger, Laura Harper; Lerman, Dorothea C.

    2011-01-01

    Previous research indicates that pairing pictures with associated words when teaching sight-word reading may hinder acquisition (e.g., Didden, Prinsen, & Sigafoos, 2000; Singh & Solman, 1990; Solman & Singh, 1992). The purpose of the current study was to determine whether this phenomenon was due to a previously learned association between the…

  8. Codes, Ciphers, and Cryptography--An Honors Colloquium

    ERIC Educational Resources Information Center

    Karls, Michael A.

    2010-01-01

    At the suggestion of a colleague, I read "The Code Book", [32], by Simon Singh to get a basic introduction to the RSA encryption scheme. Inspired by Singh's book, I designed a Ball State University Honors Colloquium in Mathematics for both majors and non-majors, with material coming from "The Code Book" and many other sources. This course became…

  9. Music on the Move: Methodological Applications of Bernstein's Concepts in a Secondary School Music Context

    ERIC Educational Resources Information Center

    McPhail, Graham J.

    2016-01-01

    In 2002 Parlo Singh outlined Bernstein's theory of the pedagogic device, elaborating the potential in Bernstein's complex theoretical framework for empirical research. In particular, Singh suggests that Bernstein's concepts provide the means of making explicit the macro and micro structuring of knowledge into pedagogic communication. More…

  10. The New Leader of the Free World

    ERIC Educational Resources Information Center

    Williamson, Kevin D.

    2012-01-01

    On January 20, 2009, Dr. Manmohan Singh, the prime minister of India, became the leader of the free world. The free world's attention was focused elsewhere: Senator Barack Obama, who on that day became President Barack Obama, quietly abdicated the role now taken up by Dr. Singh, having run an election campaign premised upon the ever-present but…

  11. Comment on ‘A technique for image encryption using digital signature’

    NASA Astrophysics Data System (ADS)

    Hernández Encinas, L.; Peinado Domínguez, A.

    2006-12-01

    The security of a recently proposed technique for encryption images by Sinha and Singh [A. Sinha, K. Singh, Opt. Commun. 218 (2003) 229], based on the use of digital signatures and error correcting codes, is analyzed. The proposed cryptosystem is shown to have some weakness. In fact, the secret key and the original image can be recovered efficiently by a brute force attack.

  12. The Surgeon General's Facing Addiction Report: An Historic Document for Healthcare.

    PubMed

    Levy, Sharon; Seale, J Paul; Osborne, Victoria A; Kraemer, Kevin L; Alford, Daniel P; Baxter, Jeffrey; Finnell, Deborah S; Kunins, Hillary; Walley, Alexander Y; Lewis, David C; MacLane-Baeder, Doreen; Gordon, Adam J

    2017-03-22

    The publication of Facing Addiction in America: The Surgeon General's Report on Alcohol, Drugs, and Health presents an historic moment not only for the field of addiction medicine, but also for the United States as a nation. The Board of Directors of the Association for Medical Education and Research in Substance Abuse (AMERSA), on behalf of our organization, would like to express our appreciation of the efforts of Dr. Vivek Murthy and the Surgeon General's Office to publish the first surgeon general's report covering substance misuse and substance use disorders.

  13. 77 FR 68202 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ... renewable two-year period. They are: Henry W. Adams (AL) Timothy S. Ballard (NC) Larry W. Barnes (AR...) Ranjodh Singh (MA) Mark A. Thornton (WA) Roy F. Varnado, Jr. (LA) Michael J. Welle (MN) Eugene E....

  14. New Maximally Entangled States for Pattern-Association Through Evolutionary Processes in a Two-Qubit System

    NASA Astrophysics Data System (ADS)

    Singh, Manu Pratap; Rajput, Balwant S.

    2017-04-01

    New set of maximally entangled states (Singh-Rajput MES), constituting orthonormal eigen bases, has been revisited and its superiority and suitability in pattern-association (Quantum Associative Memory, QuAM) have been demonstrated. Using these MES as memory states in the evolutionary process of pattern storage in a two-qubit system, it has been shown that the first two states of Singh-Rajput MES are useful for storing the pattern |11> and the last two of these MES are useful in storing the pattern |10> Recall operations of quantum associate memory (QuAM) have been conducted through evolutionary process in terms of unitary operators by separately choosing Singh-Rajput MES and Bell's MES as memory states and it has been shown that Singh-Rajput MES as valid memory states for recalling the patterns in a two-qubit system are much more suitable than Bell's MES.

  15. Why human health and health ethics must be central to climate change deliberations.

    PubMed

    Singh, Jerome Amir

    2012-01-01

    Jerome Singh argues that health ethics principles must be afforded equal status to economics principles in climate change deliberations, and that the health community must play more of a leadership role.

  16. From the NIH Director: A Global Health System

    MedlinePlus

    ... turn Javascript on. During his recent visit to India, NIH Director Dr. Elias Zerhouni (left) met with Manmohan Singh, Prime Minister of India, to discuss NIH's substantial medical research collaborations with ...

  17. Zinc in diet

    MedlinePlus

    ... reduce your risk of becoming sick with the common cold. Starting to take zinc supplements within 24 hours ... 26. Singh M, Das RR. Zinc for the common cold. Cochrane Database Syst Rev . Jun18;6:CD001364. PMID: ...

  18. Erratum

    PubMed Central

    2017-01-01

    Cherian J, Singh R, Varma M, Vidyasagar S, Mukhopadhyay C. Community-acquired methicillin-resistant pyogenic liver abscess: a case report. J Investig Med High Impact Case Rep. 2016;4(3):1-3. doi: 10.1177/2324709616660576

  19. International Conference on Human Relations.

    DTIC Science & Technology

    2007-11-02

    Festinger , Sherif, Ex, Rohrer, Pinto, Singh, and Mailhiot. One outcome of the Conference was the formation of a working committee to establish an International Documentation and Information Center for the field of Human Relations.

  20. Major geomagnetic storm due to solar activity (2006-2013).

    NASA Astrophysics Data System (ADS)

    Tiwari, Bhupendra Kumar

    Major geomagnetic storm due to solar activity (2006-2013). Bhupendra Kumar Tiwari Department of Physics, A.P.S.University, Rewa(M.P.) Email: - btiwtari70@yahoo.com mobile 09424981974 Abstract- The geospace environment is dominated by disturbances created by the sun, it is observed that coronal mass ejection (CME) and solar flare events are the causal link to solar activity that produces geomagnetic storm (GMS).CMEs are large scale magneto-plasma structures that erupt from the sun and propagate through the interplanetary medium with speeds ranging from only a few km/s to as large as 4000 km/s. When the interplanetary magnetic field associated with CMEs impinges upon the earth’s magnetosphere and reconnect occur geomagnetic storm. Based on the observation from SOHO/LASCO spacecraft for solar activity and WDC for geomagnetism Kyoto for geomagnetic storm events are characterized by the disturbance storm time (Dst) index during the period 2006-2013. We consider here only intense geomagnetic storm Dst <-100nT, are 12 during 2006-2013.Geomagnetic storm with maximum Dst< -155nT occurred on Dec15, 2006 associated with halo CME with Kp-index 8+ and also verify that halo CME is the main cause to produce large geomagnetic storms.

  1. Installation Restoration Program. Phase 2. Confirmation/Quantification Stage 2, Moody Air Force Base, Georgia. Appendices. Volume 2

    DTIC Science & Technology

    1988-11-01

    the Florida Pollution Control Association. November 1984. With U. Singh, K. Cable, T. Emenhiser, J.I. Garcia - Bengochea, and J. Orban. Remedial...Conference of the Water Pollution Control Federation. October 1984. With U. Singh, T. Emenhiser, J.I. Garcia -Bengochea, and J. 5i Orban. Remedical...Emenhiser, J.I. Garcia -Bengochea, and J. Orban. Sampling the Biscayne Aquifer for Toxic Pollutants. Proceedings of the Conference on Municipal, Hazardous

  2. Near East/South Asia Report.

    DTIC Science & Technology

    2007-11-02

    Hungarian Minister asked for early clearance for the collaboration project between Kirloskar and Raba. Mr Singh said that efforts should be made to...country projects such as joint tendering and turn- key projects . Mr Singh said 100% export orient units with buy-back arrangements and joint ventures...European Community Reviewed (LA VIE ECONOMIQUE, 30 Sep 83) 17 -a - [III - NE & A - 121] Production of Citrus Fruit Reviewed (ALMAGHRIB, 30 Sep 83

  3. Trajectory Optimization With Detection Avoidance for Visually Identifying an Aircraft

    DTIC Science & Technology

    2005-06-01

    Thesis Supervisor Certified by Brent Appleby Lecturer in Aeronautics and CSDL Technical Supervisor Thesis Advisor Accepted by Jaime Peraire Professor of...Leena Singh Title: Senior Member of the Technical Staff Thesis Advisor: Dr. Brent Appleby Title: Division Leader - Control, Information, and Decision...Systems 3 [This page intentionally left blank.] Acknowledgments I would like to thank my advisors Leena Singh and Brent Appleby for their help with this

  4. New Maximally Entangled States and Pattern Classification in Two-Qubit System

    NASA Astrophysics Data System (ADS)

    Singh, Manu Pratap; Rajput, B. S.

    2014-09-01

    Pattern classifications have been performed by employing the method of Grover's iteration on Bell's MES and Singh-Rajput MES in two-qubit system and it has been demonstrated that for any pattern classification in a two-qubit system the maximally entangled states of Singh-Rajput eigen basis provide the most suitable choice of search states while in no case any of Bell's states is suitable for such pattern classifications.

  5. Bone mineral density in young Indian adults with traumatic proximal femoral fractures. A case control study.

    PubMed

    Gulati, Divesh; Kumar, Sudhir; Arora, Anil; Aggarwal, Aditya Nath; Bhargava, S K

    2010-06-01

    There is scarcity of data on osteoporosis in India for the age group of 20-40 years when peak bone mass is achieved. This study aimed to assess bone mineral density (BMD) in patients in this age group with traumatic proximal femoral fractures, and to compare it with age matched controls. Thirty patients aged 20 to 40 years with traumatic proximal femoral fractures and 30 healthy volunteers within the same age group were included in the study. Radiographs of the pelvis were taken to determine the Singh index, and DEXA scan of the unaffected hip was done to assess BMD. Fracture cases were compared with controls for significant difference in BMD. The male to female ratio of the study was 2:1. Based on Singh's index, 60% of fracture cases and 20% of controls were osteoporotic. T scores by DEXA revealed that 24 patients with fracture and 22 controls had osteopenia or osteoporosis. There was a significant difference in the Singh index between the two groups and no significant difference in BMD assessed by DEXA scan. No agreement was found between BMD determined by DEXA and Singh's index. The study points that our population fails to attain an adequate peak bone mass. It also questions the applicability of Western data to Indian population. The findings also indicate that Singh's Index cannot substitute DEXA for diagnosis of osteoporosis.

  6. Comment on 'Further evidence for lightning at Venus'

    NASA Technical Reports Server (NTRS)

    Taylor, H. A., Jr.; Cloutier, P. A.

    1987-01-01

    In contradiction to the findings of Singh and Russell (1986), the Pioneer Venus Orbiter (PVO) electric-field data are not found to provide evidence for either lightning or volcanism at Venus. It is suggested that the noise considered by Singh and Russell to be clustered at low altitudes actually appears frequently at high altitudes. The frequent appearance of the broadband noise in the upper ionosphere indicates that this noise, like that attributed to lightning by Scarf et al. (1980), is actually generated within the ionosphere near the PVO by the solar wind interaction with the ionosphere.

  7. Enhancement of Radiation Tolerance by Interfaces in Nanostructured Metallic Materials

    DTIC Science & Technology

    2013-06-05

    Bacon , Philosophical Magazine, 86 (2006) 2295-2313. [10] N.M. Ghoniem, B.N. Singh, L.Z. Sun, T. Dı́az de la Rubia, Journal of Nuclear Materials, 276...327 (2010) 1587-1588. [33] Y.N. Osetsky, D.J. Bacon , A. Serra, B.N. Singh, S.I. Golubov, Journal of Nuclear Materials, 276 (2000) 65-77. [34] D.J... Bacon , Y.N. Osetsky, R. Stoller, R.E. Voskoboinikov, Journal of Nuclear Materials, 323 (2003) 152-162. [35] Y. Matsukawa, S.J. Zinkle, Science, 318

  8. Comment on 'A re-examination of impulsive VLF signals in the night ionosphere of Venus'

    NASA Astrophysics Data System (ADS)

    Taylor, H. A.; Cloutier, P. A.

    1991-04-01

    Taylor and Cloutier (TC, 1988) previously argued that Singh and Russell (SR, 1986) wrongly identified telemetry interference as VLF broadband signals originating in Venus 'lightning events'. A response was made by Russell and Singh (RS, 1989). This comment criticizes RS, arguing that the SR did not distinguish between signal and noise and that RS makes false claims about the SR analysis. In a reply to TC, Russell argues that the SR paper, while flawed, was not intended to be quantitative and succeeds in bringing attention to the morphology of the signals seen in the upper three channels of the Pioneer Venus electric field detector.

  9. Big Bang Day: 5 Particles - 5. The Next Particle

    ScienceCinema

    None

    2016-07-12

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 5. The Next Particle The "sparticle" - a super symmetric partner to all the known particles could be the answer to uniting all the known particles and their interactions under one grand theoretical pattern of activity. But how do researchers know where to look for such phenomena and how do they know if they find them? Simon Singh reviews the next particle that physicists would like to find if the current particle theories are to ring true.

  10. Comment on 'A re-examination of impulsive VLF signals in the night ionosphere of Venus'

    NASA Technical Reports Server (NTRS)

    Taylor, H. A., Jr.; Cloutier, P. A.

    1991-01-01

    Taylor and Cloutier (TC, 1988) previously argued that Singh and Russell (SR, 1986) wrongly identified telemetry interference as VLF broadband signals originating in Venus 'lightning events'. A response was made by Russell and Singh (RS, 1989). This comment criticizes RS, arguing that the SR did not distinguish between signal and noise and that RS makes false claims about the SR analysis. In a reply to TC, Russell argues that the SR paper, while flawed, was not intended to be quantitative and succeeds in bringing attention to the morphology of the signals seen in the upper three channels of the Pioneer Venus electric field detector.

  11. JPRS Report, Near East & South Asia.

    DTIC Science & Technology

    2007-11-02

    speculation and putting the cart before the horse. The borders between many countries in the world are changing all the time in conformity with...Minister Rajiv Gandhi and home minister, Buta Singh. In a brief interview with SUNDAY, Abdullah holds forth on the roots of the problem of

  12. Topics in Culture Learning, Volume 5.

    ERIC Educational Resources Information Center

    Brislin, Richard W., Ed.; Hamnett, Michael P., Ed.

    The first section of this volume includes articles on cross-cultural teaching: "Mau Piailug's Navigation of Hokule'a from Hawaii to Tahiti," by David Lewis; "The New World Order and the Globalization of Social Science: Some Implications for Teaching Cross-Culturally," by Amarjit Singh; "Ponape: Cross-Cultural Contact,…

  13. An Academic Survey Concerning High School and University Students' Attitudes and Approaches to Problem Solving in Chemistry

    ERIC Educational Resources Information Center

    Duran, Muharrem

    2016-01-01

    The aim of this study is to reveal differences between attitudes and approaches of students from different types of high school and the first grade of university towards problem solving in chemistry. For this purpose, the scale originally developed by Mason and Singh (2010) to measure students' attitude and approaches towards problem solving in…

  14. Editorial: Looking to the Future of Hydrologic Engineering

    EPA Science Inventory

    Being one of the more recent journals of the American Society of Civil Engineers, the Journal of Hydrologic Engineering (JHE) has made significant strides under the forward-thinking leadership of previous editors (M. Levent Kavvas 1996-2004, and V. P. Singh, 2004-2012) si...

  15. Genetics Home Reference: Aicardi-Goutieres syndrome

    MedlinePlus

    ... RC, Gornall H, Singh-Grewal D, Alcausin M, Rice GI, Crow YJ. Familial Aicardi-Goutières syndrome due ... doi: 10.1002/art.27367. Citation on PubMed Rice G, Patrick T, Parmar R, Taylor CF, Aeby ...

  16. Time-Resolved Electronic Relaxation Processes in Self-Organized Quantum Dots

    DTIC Science & Technology

    2005-05-16

    Colocci, A. Bosacchi, P. Frigeri , and S. Franchi, Appl. Phys. Lett. 69, 3354 (1996). 8. P. Battacharya, K. K. Kamath, J. Singh, D. Klotzkin, J...Sercel, Phys. Rev. B 56, 13314 (1997). 23. S. Sanguinetti, M. Henini, M. Grassi Alessi, M. Capizzi, P. Frigeri , and S. Franchi, Phys. Rev. B 60, 8276

  17. Height, weight and body mass index of girls and boys in a rural school in Punjab India

    Technology Transfer Automated Retrieval System (TEKTRAN)

    All the students at this Bhagat Puran Singh Memorial School in Punjab, India were educated about the importance of caloric intake and physical activity. Body weight and height were recorded once a month for 12 consecutive months for 632 students, age 8-23 years (7584 observations). For US and Euro...

  18. Effect of mean load on the non-linear behavior of spur gear noise source

    NASA Technical Reports Server (NTRS)

    Kahraman, Ahmet; Singh, Rajendra

    1989-01-01

    An analytical technique for estimating noise generation by spur-gear pairs with backlash is developed using the results obtained by Comparin and Singh (1989). The derivation of the governing equations is outlined, and numerical results for sample problems are presented in graphs. Good agreement with published experimental data (Munro, 1962) is demonstrated.

  19. Reciprocal Continuity and Common Fixed Point for two Pairs of Self-Maps Satisfying a Generalized Inequality

    NASA Astrophysics Data System (ADS)

    Phaneendra, T.; Swatmaram

    2012-10-01

    We obtain a common fixed point for two pairs of self-maps on a complete metric space, one of which is reciprocally continuous and compatible, while the other weakly compatible, where all the four maps satisfy a generalized inequality. Our result is a significant generalization of that of Singh and Mishra.

  20. Scalable Effective Approaches for Quadratic Assignment Problems Based on Conic Optimization and Applications

    DTIC Science & Technology

    2012-02-09

    several optimization models and algorithm design for problems from computer vision and learning , research on sparse solutions in quadratic optimization...following papers: [9] L. Mukherjee, V. Singh, J. Peng and C. Hinrichs. Learning kernels for variants of normalized cuts: Convex relaxations and...are very small gaps compared to state-of-the-art knowledge in comunications . Table 1. Bounds for adjacency matrix

  1. CYTOTOXICITY AND CELL SIGNALING IN MH-S CELLS: RELATIVE POTENCY OF DIESEL AND COAL COMBUSTION PARTICLES

    EPA Science Inventory

    Cytotoxicity and Cell Signaling in MH-S Cells: Relative Potency of Diesel and Coal Combustion Particles P. Singh1, Y. Kostetski2, M. Daniels1, T. Stevens3 and MI Gilmour 1USEPA, RTP, NC, 2National University of Singapore, Singapore, 3University of North Carolina, Chapel Hill, NC<...

  2. The Nereus Hybrid Underwater Robotic Vehicle for Global Ocean Science Operations to 11,000m Depth

    DTIC Science & Technology

    2008-09-01

    full extension 30+ lb Controllable grip closure force 0-100 lbf Stowed height 41.5” Wrist rotate torque 180 in-lb Weight in air (sea water) 105 lb...Michigan, May 1999. [35] D. R. Yoerger, A. M. Bradley, B. B. Walden, H. Singh, and R. Bach- mayer . Surveying a Subsea Lava Flow Using the Autonomous

  3. Frequency chirping for resonance-enhanced electron energy during laser acceleration

    NASA Astrophysics Data System (ADS)

    Gupta, D. N.; Suk, H.

    2006-04-01

    The model given by Singh-Tripathi [Phys. Plasmas 11, 743 (2004)] for laser electron acceleration in a magnetic wiggler is revisited by including the effect of laser frequency chirping. Laser frequency chirp helps to maintain the resonance condition longer, which increases the electron energy gain. A significant enhancement in electron energy gain during laser acceleration is observed.

  4. EFFECTS OF DIESEL EXHAUST ON PULMONARY RESPONSES DURING ALLERGIC SENSITIZATION TO AEROSOLIZED OVALBUMIN IN BALB/C MICE

    EPA Science Inventory

    Effects of Diesel Exhaust on Pulmonary Responses During Allergic Sensitization to Aerosolized Ovalbumin in BALB/c Mice. P. Singh1, M.J. Daniels1, D. Andrews1, E. Boykin1, W. P. Linak2 and M.I. Gilmour1. 1USEPA, ORD, NHEERL, RTP, NC. 2 USEPA, ORD, NRMRL, RTP, NC.

    Inhala...

  5. Wireless Content Repurposing Architecture for DC Command and Control

    DTIC Science & Technology

    2003-09-01

    COMMAND AND CONTROL by Robert J. Suh September 2003 Thesis Advisor: Gurminder Singh Second Reader: Perry McDowell...data sources , gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this...3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE: Wireless Content Repurposing Architecture for DC Command and Control

  6. Characterization of Compressive Creep Behavior of Oxide/Oxide Composite with Monazite Coating at Elevated Temperature

    DTIC Science & Technology

    2006-03-01

    Materials, and Structures: A. Ed. Mrityunjay Singh and Todd Jensen. Westerville, OH: The American Ceramic Society, 2001. 5. Antti, M-L, E. Lara-Curzio... Emmanuel E. Boakye, Pavel Mogilevsky, and Michael K. Cinibulk. “Effectiveness of Monazite Coatings in Oxide/Oxide Composites after Long-Term Exposure

  7. Can Exosomes Induced by Breast Involution Be Markers for the Poor Prognosis and Prevention of Postpartum Breast Cancer?

    DTIC Science & Technology

    2014-07-01

    MD Betty Diamond 5d. PROJECT NUMBER 5e. TASK NUMBER E-Mail: Virginia.borges@ucdenver.edu 5f. WORK UNIT NUMBER 7. PERFORMING...KK, Biroc SL, Metz RP, Singh M, Porter W, Schedin P: Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis

  8. Two Boys with Multiple Disabilities Increasing Adaptive Responding and Curbing Dystonic/Spastic Behavior via a Microswitch-Based Program

    ERIC Educational Resources Information Center

    Lancioni, Giulio E.; Singh, Nirbhay N.; O'Reilly, Mark F.; Sigafoos, Jeff; Didden, Robert; Oliva, Doretta

    2009-01-01

    A recent study has shown that microswitch clusters (i.e., combinations of microswitches) and contingent stimulation could be used to increase adaptive responding and reduce dystonic/spastic behavior in two children with multiple disabilities [Lancioni, G. E., Singh, N. N., Oliva, D., Scalini, L., & Groeneweg, J. (2003). Microswitch clusters to…

  9. Motion Estimation from Image and Inertial Measurements

    DTIC Science & Technology

    2004-11-01

    gross mistracking have been explored, corresponding to 3.0, 6.0, and 9.0 pixel thresholds for the change in error. The 3.0 pixel threshold is the most rea ...Experimental comparison of techniques for lo- calization andmapping using a bearing-only sensor. In Daniela Rus and Sanjiv Singh, editors, Experimental

  10. Prospects for Adult Education and Development in Asia and the Pacific. Report of a Regional Seminar (Bangkok, November 24-December 4, 1980).

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and the Pacific.

    Adult education and the economic development of the countries of Asia and the Pacific was discussed at a UNESCO conference held in Bangkok in November-December, 1980. The conference was opened by Raja Roy Singh, who emphasized the crucial significance of adult education in national development. He said that development is no longer construed only…

  11. Evaluation of Simulated Photochemical Partitioning of Oxidized Nitrogen in the Upper Troposphere

    EPA Science Inventory

    Regional and global chemical transport models underpredict NOx (NO +NO2) in the upper troposphere where it is a precursor to the greenhouse gas ozone. The NOx bias has been shown in model evaluations using aircraft data (Singh et al., 2007) and to...

  12. Stimuli Responsive Amphiphilic Assemblies

    DTIC Science & Technology

    2013-11-18

    Enzyme- Sensitive, Amphiphilic- Dendrimer -Based Nanoparticles through Photochemical Crosslinking, Chemistry - A European Journal, (10 2011): 0. doi...17, 2012 (Organizers: R. P. Singh) 8th International Dendrimer Symposium (IDS-8), Madrid, Spain, June 23-27, 2013 (Organizers: Dr. M’Angeles

  13. Strategic Human Resource Development. Symposium.

    ERIC Educational Resources Information Center

    2002

    This document contains three papers on strategic human resource (HR) development. "Strategic HR Orientation and Firm Performance in India" (Kuldeep Singh) reports findings from a study of Indian business executives that suggests there is a positive link between HR policies and practices and workforce motivation and loyalty and…

  14. Adult Learning and the Future of Work.

    ERIC Educational Resources Information Center

    Singh, Madhu, Ed.

    This book contains 15 papers: "Introduction" (Madhu Singh); "Adult Learning and the Transformation of Work" (Paul Belanger); "Future of Work and Adult Learning" (Ettore Gelpi); "The Obligation of Education in the Face of Globalisation" (Nicole Arnaud); "Lifelong Learning and Vocational Education and…

  15. Four Methods of Handling Missing Data in Predicting Educational Achievement.

    ERIC Educational Resources Information Center

    Witta, E. Lea

    Four methods of handling missing data were applied to missing values for variables selected from the National Education Longitudinal Study of 1988. Variables used were those selected by K. Singh and M. Ozturk (1999) for a study concerning high school students' academic achievement and work. Samples selected consisted of 100 cases, 300 cases, and…

  16. Fictionalized Indian English Speech and the Representations of Ideology in Indian Novels in English

    ERIC Educational Resources Information Center

    Muthiah, Kalaivahni

    2009-01-01

    I investigate the spoken dialogue of four Indian novels in English: Mulk Raj Anand's "Untouchable" (1935), Khushwant Singh's "Train to Pakistan" (1956), Rasipuram Krishnaswami Narayan's "The World of Nagaraj" (1990), and Rohinton Mistry's "Family Matters" (2002). Roger Fowler has said that literature, as a form of discourse, articulates ideology;…

  17. Postscript: Qualitative and Quantitative Processes in the Perception of Achromatic Transparency

    ERIC Educational Resources Information Center

    Albert, Marc K.

    2008-01-01

    All of the data reported in Robilotto, Khang, and Zaidi (2002) Robilotto and Zaidi (2004), and Singh and Anderson (2002) are consistent with Robilotto and Zaidi's theory that perceived transparency (or opacity) is determined by the perceived contrast of the filter region. Kasrai and Kingdom's (2001) results also appear largely consistent with the…

  18. From Village to the World: Books with Hope

    ERIC Educational Resources Information Center

    Asher, Rikki

    2008-01-01

    The Pardada Pardadi Girls Vocational School (PPGVS) in India was established in 2000 by Virendera (Sam) Singh, a retired U.S. Dupont South Asia department head to address the issue of gender bias in India. According to the school's website, nearly half of India's population is illiterate: males outnumber females two-to-one in literacy and drop-out…

  19. Evaluating outreach

    NASA Astrophysics Data System (ADS)

    McCracken, Shane

    2015-12-01

    In reply to the physicsworld.com blog post “Quantifying the success of public engagement” (22 October, http://ow.ly/TIWYJ), which discussed criticisms (made by science writer Simon Singh) of certain projects designed to boost interest in science.

  20. The Mathematics of "Star Trek"--An Honors Colloquium

    ERIC Educational Resources Information Center

    Karls, Michael A.

    2011-01-01

    After the success of a course on cryptography for a general audience, based on Simon Singh's "The Code Book" [49], I decided to try again and create a mathematics course for a general audience based on "The Physics of Star Trek" by Lawrence Krauss [32]. This article looks at the challenges of designing a physics-based mathematics course "from…

  1. A Framework for Inclusion: Plurilingual Teachers in Day and Community Schools

    ERIC Educational Resources Information Center

    Cruickshank, Ken

    2015-01-01

    Linguistic and cultural diversity is becoming a feature of the teaching profession in OECD countries with the increase in global migration and mobility (Reid, Collins & Singh, 2014). Plurilingual teachers, however, tend to experience marginalisation in terms of gaining employment and in their workplace experiences. Although there is a body of…

  2. Mechanisms of Modal and Amodal Interpolation

    ERIC Educational Resources Information Center

    Albert, Marc K.

    2007-01-01

    P. J. Kellman and T. F. Shipley (1992) and P. J. Kellman, P. Garrigan, and T. F. Shipley (2005) suggested that completion of partly occluded objects and illusory objects involve the same or similar mechanisms at critical stages of contour interpolation. B. L. Anderson, M. Singh, and R. W. Fleming and B. L. Anderson (2007) presented a number of…

  3. Exploring Klein Bottles through Pottery: A STEAM Investigation

    ERIC Educational Resources Information Center

    Smith, Christopher E.; Paré, Jana N.

    2016-01-01

    While one author was reading "The Simpsons and Their Mathematical Secrets by Simon Singh" (2013) in preparation for a presentation, the second author asked what in the book would be interesting to discuss. The topic of Klein bottles was on the first author's mind at that moment, so he tried to describe and explain the form to her--a real…

  4. Principles of Contour Information: Reply to Lim and Leek (2012)

    ERIC Educational Resources Information Center

    Singh, Manish; Feldman, Jacob

    2012-01-01

    Lim and Leek (2012) presented a formalization of information along object contours, which they argued was an alternative to the approach taken in our article (Feldman & Singh, 2005). Here, we summarize the 2 approaches, showing that--notwithstanding Lim and Leek's (2012) critical rhetoric--their approach is substantially identical to ours,…

  5. Children with Multiple Disabilities and Minimal Motor Behavior Using Chin Movements to Operate Microswitches to Obtain Environmental Stimulation

    ERIC Educational Resources Information Center

    Lancioni, Giulio E.; O'Reilly, Mark F.; Singh, Nirbhay N.; Sigafoos, Jeff; Tota, Alessia; Antonucci, Massimo; Oliva, Doretta

    2006-01-01

    In these two studies, two children with multiple disabilities and minimal motor behavior were assessed to see if they could use chin movements to operate microswitches to obtain environmental stimulation. In Study I, we applied an adapted version of a recently introduced electronic microswitch [Lancioni, G. E., O'Reilly, M. F., Singh, N. N.,…

  6. The Moderating Role of Adult Connections in High School Students' Sense of School Belonging

    ERIC Educational Resources Information Center

    Tillery, Amy Dutton

    2009-01-01

    Researchers have demonstrated that students who had a strong sense of school belonging exhibited greater academic motivation and performance (E. Anderman, 2002; Faircloth & Hamm, 2005), had fewer emotional and behavioral difficulties (Furrer & Skinner, 2003; McMahon, Singh, Garner, & Benhorin; 2004), and were less likely to dropout of…

  7. They Can Still Act Chinese and Be Canadian at the Same Time: Reflections on Multiculturalism and the Alberta Art Curriculum

    ERIC Educational Resources Information Center

    Eiserman, Jennifer

    2009-01-01

    This paper explores how Canadian identity remains a white identity through an examination of the ways in which cultural diversity in Canada has been promoted and controlled in law and in practice through Jakeet Singh's (2004) notion of "culture-blind multiculturalism." It then turns to one instance of this kind of myopic cultural…

  8. Bringing the concepts of peer coaches and local health workers from Africa to Harlem.

    PubMed

    Singh, Prabhjot

    2012-12-01

    Prabhjot Singh, a PhD scientist and medical resident, saw the effectiveness of community health workers while working in Africa. Now he helps run a New York-based organization that trains peer coaches to help struggling Americans manage their health.

  9. Age, Gender and Job Satisfaction among Elementary School Head Teachers in Pakistan

    ERIC Educational Resources Information Center

    Ghazi, Safdar Rehman; Maringe, Felix

    2011-01-01

    The purpose of this study was to explore general job satisfaction of elementary school head teachers in Pakistan with respect to their age and gender. One hundred and eighty head teachers were sampled from government elementary schools of Toba Tek Singh, Punjab, Pakistan, to collect the relevant data using a modified version of the Minnesota…

  10. Teaching with the Flow: Fixity and Fluidity in Education

    ERIC Educational Resources Information Center

    Pennycook, Alastair

    2005-01-01

    In this paper I suggest that as educators we need to understand that the spaces and cultures our students inhabit are to be found not so much in predefinitions of cultural background or in studies of classrooms as cultural spaces as in the transcultural flows with which our students engage. Thus, my argument is not only that, as Singh and Doherty…

  11. Behavioral and Temporal Pattern Detection Within Financial Data With Hidden Information

    DTIC Science & Technology

    2012-02-01

    The StateRover, http://www.time-rover.com [Si] S. Singh, The Code Book: The Science of Secrecy from Ancient Egypt to Quantum Cryptography . London......OMB No. 0704-0188 Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for

  12. Breeding lines and host QTL interaction with bacterial strains

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Resistance to common bacterial blight (CBB) is controlled by more than 20 QTL (Miklas and Singh, 2007). A QTL on Pv10 linked to SAP6 SCAR markers is derived from common bean. Higher levels of resistance associated with BC420 QTL on Pv06 (Yu et al., 2000) and SU91-CG11 QTL on Pv08 (Pedraza et al., 20...

  13. Cosmopolitanism and Rural Education: A Conversation

    ERIC Educational Resources Information Center

    Reid, Carol

    2015-01-01

    In this paper, recent research into the global movement of teachers [C. Reid, J. Collins, and M. Singh. 2014. "Global Teachers, Australian Perspectives: Goodbye Mr Chips, Hello Ms Banerjee." Singapore: Springer] and their experiences in rural areas of Australia are discussed in order to make the case for a cosmopolitan education theory…

  14. Examining the Effects of Jyoti Meditation on Stress and the Moderating Role of Emotional Intelligence

    ERIC Educational Resources Information Center

    Gutierrez, Daniel; Conley, Abigail H.; Young, Mark

    2016-01-01

    The authors examined whether Jyoti meditation (JM), a spiritually based meditation (Singh, 2012), influenced student counselors' (N = 60) level of stress and emotional intelligence (EI). Results from a randomized controlled trial and growth curve analysis provided a multilevel model in which JM reduced stress and EI moderated the effect.

  15. Markets, Distribution, and Exchange after Societal Cataclysm

    DTIC Science & Technology

    1988-03-01

    heterogeneous, as with the copper plates exchanged by the Kwakiutl in their potlatches . These coppers derive their value from their particular histories of...1922, Singh Uberoi 1962), blankets and coppers in Kwakiutl potlatch (Codere 1950), iron rods among the Tiv of central Nigeria (Bohannan 1959), or as

  16. MRI-DTI Tractography to Quantify Brain Connectivity in Traumatic Brain Injury

    DTIC Science & Technology

    2009-04-01

    to Traumatic Brain Injury and Alzheimer Disease ”, 5-th International Annual Symposium of the Brain Mapping and Intraoperative Surgical Planning... Alzheimer Disease , Proc Intl Soc Mag Reson Med 15: 343, 2007. 9. Singh M and Jeong J-W, “ICA based multi-fiber tractography” Proceedings, 17-th

  17. DIESEL AND CARBON PARTICLES ENHANCE HOUSE DUST MITE-INDUCED PULMONARY HYPERSENSITIVITY IN BROWN NORWAY RATS

    EPA Science Inventory

    Diesel and Carbon Particles Enhance House Dust Mite-Induced Pulmonary Hypersensitivity in Brown Norway Rats. P. Singh1, M.J. Daniels2, D. Winsett2, J. Richards2, K. Crissman2, M. Madden2 and M.I. Gilmour2. 1NCSU, Raleigh, NC and 2 USEPA, Research Triangle Park, NC.

    Ep...

  18. CHARACTERIZATION OF IMMEDIATE AND LATE PHASE AIRWAY RESPONSES TO HOUSE DUST MITE CHALLENGE IN BROWN NORWAY RATS AND CORRELATIONS AMONG PHYSIOLOGICAL MEDIATORS

    EPA Science Inventory

    CHARACTERIZATION OF IMMEDIATE AND LATE PHASE AIRWAY RESPONSES TO HOUSE DUST MITE CHALLENGE IN BROWN NORWAY RATS AND CORRELATIONS AMONG PATHOPHYSIOLOGICAL MEDIATORS (P.
    SinghI, D.W. Winsett2, M.J. Daniels2, J. Richards2, K. Crissman2, D.L. Doerfler2 and M.I. Gilmour2, 1NCSU, Ra...

  19. Transient Delivery of Adenosine as a Novel Therapy to Prevent Epileptogenesis

    DTIC Science & Technology

    2013-08-01

    Williams-Karnesky,1,2 Ursula S. Sandau,1 Theresa A. Lusardi,1 Nikki K. Lytle,1 Joseph M. Farrell,1 Eleanor M. Pritchard,3 David L. Kaplan,3 and...receptor activation in a mouse model of pharmacoresistant epilepsy. Epilepsia. 2003;44(7):877–885. 25. Cui XA, Singh B, Park J, Gupta RS

  20. COMPARATIVE TOXICITY OF DIFFERENT EMISSION PARTICLES IN MURINE PULMONARY EPITHELIAL CELLS AND MACROPHAGES

    EPA Science Inventory

    Comparative Toxicity of Different Emission Particles in Murine Pulmonary Epithelial Cells and Macrophages. T Stevens1, M Daniels2, P Singh2, M I Gilmour2. 1 UNC, Chapel Hill 27599 2Experimental Toxicology Division, NHEERL, RTP, NC 27711

    Epidemiological studies have shown ...

  1. 78 FR 60250 - Order Denying Export Privileges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... Bureau of Industry and Security Order Denying Export Privileges In the Matter of: Vikramaditya Singh, a.k... attempting to cause the export of digital microwave radios to Iran without the required authorization from... probation, six months of home confinement and a $100,000 fine. Section 766.25 of the Export...

  2. Back Pain and Endurance Training of Back Muscles: Justification for Further Study in Helicopter Pilots.

    DTIC Science & Technology

    2007-11-02

    clinical trial [see comments]. Spine 1990Dec;15(12):1317-1320. 17. Dul J, Hildebrandt VH. Ergonomie guidelines for the prevention of low back pain at...Congress 1962;XI Congress, Madrid: 145-151. 56. Singh R. Backache in Chetak Crew and Suggested Ergonomie Improvements in Aircraft Seat Design

  3. Research of Ionospheric Scintillation in Asia (RISA)

    DTIC Science & Technology

    2014-03-01

    as from satellite observations (Bilitza et al., 2003). More information on the IRI project, including information on the IRI Newsletter and the IRI...Science, 36 (6), 1559–1572. Chauhan, Vishal., Singh, O.P. A morphological study of GPS-TEC dataat Agra and their comparison with the IRI model. Adv

  4. Proof of Concept Demonstration of the Hybrid Remotely Operated Vehicle (HROV) Light Fiber Tether System

    DTIC Science & Technology

    2008-09-01

    capable of exploring and mapping the seafloor with sonars, cameras, and other on-board sensors . Nereus can be converted at sea to become a remotely...San Diego, CA [4] D.R. Yoerger, A.M. Bradley. B.B.Walden, H. Singh, and R. Bachmayer. Surveying a Subsea Lava Fleow using the Autonomous Benthic

  5. Adaptation of Advanced Diesel Engines for Military Requirements Under Severe Environmental Conditions

    DTIC Science & Technology

    2007-11-02

    Candidate, Wayne State University 2. Inderpal Singh, Ph. D Applicant , Wyne State University 3. Naeim A. Henein, Professor and Director of Center for...23 Appendix C: SAE 2003-01-0699 ....................................... 47 Appendix D : SAE.2004-01-0931...Appendix D : Zhong, L., Henein, N. A., Bryzik, W., "Effect of Smoothing the Pressure Trace on the Interpretation of Experimental Data for Combustion in

  6. Strategy for Isolation of Gene Activation Factors

    DTIC Science & Technology

    1988-11-01

    4723-4733). 10. Singh H, LeBowitz JH, Baldwin AS, Sharp PA: Molecular cloning of an enhancer binding protein: Isolation by screening of an...expression library with a recognition site DNA. Cell, 52:415-423, 1988. 14 ii. Maniatis T, Fritsch EF, Sambrook J: Molecular cloning . A laboratory manual, Cold

  7. COMPARISON OF PULMONARY RESPONSES TO AUTOMOBILE-GENERATED AND NIST STANDARD REFERENCE MATERIAL DIESEL PARTICULATE EMISSIONS IN MICE

    EPA Science Inventory

    COMPARISON OF PULMONARY RESPONSES TO AUTOMOBILE-GENERATED AND NIST STANDARD REFERENCE MATERIAL DIESEL PARTICULATE EMISSIONS IN MICE. P. Singh1, C.A.J. Dick2, J. Richards3, M.J. Daniels3, and M.I. Gilmour3. 1NCSU, Raleigh, NC, 2UNC, Chapel Hill, NC and 3 USEPA, ORD, NHEERL, (ETD,...

  8. EFFECT OF THREE DIFFERENT SIZED FRACTIONS OF OUTDOOR PM ON INFLAMMATORY AND OXIDATIVE MARKERS IN VIVO

    EPA Science Inventory

    EFFECT OF THREE DIFFERENT SIZED FRACTIONS OF OUTDOOR PM ON INFLAMMATORY MARKERS IN VIVO
    C A J Dick', P Singh2, P. Evansky3, S Becker3 and M I Gilmour3.
    'Center For Environmental Medicine and Lung Biology, UNC, Chapel Hill, NC 27599 2NCSU, Raleigh, NC 'Experimental Toxicolog...

  9. Development of Multidisciplinary, Multifidelity Analysis, Integration, and Optimization of Aerospace Vehicles

    DTIC Science & Technology

    2010-02-27

    Optimization," IEEE Transactions on Aerospace and Electronics Systems, Vol. 34, 817-823. Singh, G. and Grandhi, R. V., "Mixed-Variable Optimization...containing the design space S. AS3. The objective function (the augmented Lagrangian function), , satisfies a Lipschitz condition. In words, the

  10. 3D Priors for Scene Learning from a Single View

    DTIC Science & Technology

    2008-05-01

    Conference on Articulated Motion and Deformable Objects, 2006. [13] Seemann, E., Leibe, B. and Schiele , B., "Multi-aspect detection of articulated objects...Seemann, E. and Schiele , B., "Pedestrian detection in crowded scenes." CVPR, 2005. [16] Wang, J. J. L. and Singh, S., "Video analysis of human

  11. A Comparison of Challenging Behaviour in an Adult Group with Down's Syndrome and Dementia Compared with an Adult Down's Syndrome Group without Dementia

    ERIC Educational Resources Information Center

    Huxley, Adam; Van-Schaik, Paul; Witts, Paul

    2005-01-01

    This study investigated the frequency and severity of challenging behaviour in adults with Down's syndrome with and without signs of dementia. Care staff were interviewed using the Aberrant Behaviour Checklist-Community version (M.G. Aman & N.N. Singh, Slosson, East Aurora, NY, 1994), to investigate the frequency and severity of challenging…

  12. Persistence of Early Emerging Aberrant Behavior in Children with Developmental Disabilities

    ERIC Educational Resources Information Center

    Green, Vanessa A.; O'Reilly, Mark; Itchon, Jonathan; Sigafoos, Jeff

    2005-01-01

    This study examined the persistence of early emerging aberrant behavior in 13 preschool children with developmental disabilities. The severity of aberrant behavior was assessed every 6 months over a 3-year period. Teachers completed the assessments using the Aberrant Behavior Checklist [Aman, M. G., & Singh, N. N. (1986). "Aberrant…

  13. Compressive Sensing for Radar and Radar Sensor Networks

    DTIC Science & Technology

    2013-12-02

    27] Hong-Sam Le, Qilian Liang, “Joint Multi-target Identification and Classification in Cognitive Radar Sensor Networks,” International Journal of Wireless Information Networks , vol...Networks," International Journal of Wireless Information Networks , vol. 18, no. 2, pp. 100-107, 2011. 8. Sukhvinder Singh, Qilian Liang, Dechang

  14. Efficacy and compatibility of a biopesticide or a neonicitinoid on the enzootic entomopathogenic fungi and natural enemies for managing the fig whitefly, Singhiella simplex

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The fig whitefly, Singhiella simplex (Singh) is a recent invasive species that has become a major pest in Florida feeding on Ficus shrubs and trees. A pilot study was conducted on a weeping fig, Ficus benjamina shrub hedge to determine the efficacy and compatibility of a biopesticide (PFR 97™=Isaria...

  15. Natural enemies managing the invasion of the Fig whitefly, Singhiella simplex (Hemiptera: Aleyrodidae), infesting a Ficus benjamina hedge

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The fig whitefly, Singhiella simplex (Singh) is a recent invasive species that has become a major pest in Florida feeding on Ficus shrubs and trees. A pilot study was conducted on a weeping fig, Ficus benjamina shrub hedge to determine the efficacy and compatibility of a biopesticide (PFR 97™=Isaria...

  16. Selecting a Benchmark Suite to Profile High-Performance Computing (HPC) Machines

    DTIC Science & Technology

    2014-11-01

    Performance Evaluation Corporation . Gainesville (VA): SPEC; c1995 [accessed 2014 Jun 2]. http://www.spec.org/. 16. Woo SC, Ohara M, Torrie E, Singh JP... communicatons systems. In Proceedings of the 30th Annual ACM/IEEE International Symposium on Microarchitecture; 1997, p. 330–335. 20. Li ML, Sasanka R, Adve

  17. Sleep Duration and Area-Level Deprivation in Twins

    PubMed Central

    Watson, Nathaniel F.; Horn, Erin; Duncan, Glen E.; Buchwald, Dedra; Vitiello, Michael V.; Turkheimer, Eric

    2016-01-01

    Study Objectives: We used quantitative genetic models to assess whether area-level deprivation as indicated by the Singh Index predicts shorter sleep duration and modifies its underlying genetic and environmental contributions. Methods: Participants were 4,218 adult twin pairs (2,377 monozygotic and 1,841 dizygotic) from the University of Washington Twin Registry. Participants self-reported habitual sleep duration. The Singh Index was determined by linking geocoding addresses to 17 indicators at the census-tract level using data from Census of Washington State and Census Tract Cartographic Boundary Files from 2000 and 2010. Data were analyzed using univariate and bivariate genetic decomposition and quantitative genetic interaction models that assessed A (additive genetics), C (common environment), and E (unique environment) main effects of the Singh Index on sleep duration and allowed the magnitude of residual ACE variance components in sleep duration to vary with the Index. Results: The sample had a mean age of 38.2 y (standard deviation [SD] = 18), and was predominantly female (62%) and Caucasian (91%). Mean sleep duration was 7.38 h (SD = 1.20) and the mean Singh Index score was 0.00 (SD = 0.89). The heritability of sleep duration was 39% and the Singh Index was 12%. The uncontrolled phenotypic regression of sleep duration on the Singh Index showed a significant negative relationship between area-level deprivation and sleep length (b = −0.080, P < 0.001). Every 1 SD in Singh Index was associated with a ∼4.5 min change in sleep duration. For the quasi-causal bivariate model, there was a significant main effect of E (b0E = −0.063; standard error [SE] = 0.30; P < 0.05). Residual variance components unique to sleep duration were significant for both A (b0Au = 0.734; SE = 0.020; P < 0.001) and E (b0Eu = 0.934; SE = 0.013; P < 0.001). Conclusions: Area-level deprivation has a quasi-causal association with sleep duration, with greater deprivation being related to

  18. Transcriptome profiling for discovery of genes involved in shoot apical meristem and flower development.

    PubMed

    Singh, Vikash K; Jain, Mukesh

    2014-12-01

    Flower development is one of the major developmental processes that governs seed setting in angiosperms. However, little is known about the molecular mechanisms underlying flower development in legumes. Employing RNA-seq for various stages of flower development and few vegetative tissues in chickpea, we identified differentially expressed genes in flower tissues/stages in comparison to vegetative tissues, which are related to various biological processes and molecular functions during flower development. Here, we provide details of experimental methods, RNA-seq data (available at Gene Expression Omnibus database under GSE42679) and analysis pipeline published by Singh and colleagues in the Plant Biotechnology Journal (Singh et al., 2013), along with additional analysis for discovery of genes involved in shoot apical meristem (SAM) development. Our data provide a resource for exploring the complex molecular mechanisms underlying SAM and flower development and identification of gene targets for functional and applied genomics in legumes.

  19. Radiative effects and the missing energy paradox in the ideal two capacitors problem

    NASA Astrophysics Data System (ADS)

    Urzúa, Gilberto A.; Jiménez, Omar; Maass, Fernando; Restuccia, Álvaro

    2016-05-01

    Starting from the Poynting theorem, which arises from the exact Maxwell equations, we establish the balance of energy for the radiating ideal two capacitors problem. This balance of energy results in a nonlinear differential equation governing the time evolution of the voltage V. Boykin, Hite and Singh, following an approach not based on first principles, were the first to obtain this nonlinear differential equation and proposed an exponentially decaying voltage as a unique solution for it. We claim that the space of solutions for this differential equation is much richer. In fact, besides the exponentially decaying solution just mentioned there exist solutions with a sudden death behavior. The radiative effect introduced by Boykin, Hite and Singh, complemented with our analysis based on the exact Maxwell equations and the characterization of the more general space of solution of the nonlinear differential equation, explain the missing energy paradox in the ideal two capacitors problem.

  20. Internal bremsstrahlung of β decay of atomic S3516

    NASA Astrophysics Data System (ADS)

    Ivanov, A. N.; Höllwieser, R.; Wellenzohn, M.; Troitskaya, N. I.; Berdnikov, Ya. A.

    2014-12-01

    We calculate the energy spectra and the branching ratio of the internal bremsstrahlung (IB) of the β- decay of atomic S3516 . We show that the theoretical spectrum of the IB, calculated within the standard model and QED, fits well the experimental spectra, measured by M. S. Powar and M. Singh [J. Phys. G: Nucl. Part. Phys. 2, 43 (1976), 10.1088/0305-4616/2/1/006] and by A. Singh and A. S. Dhaliwal [Appl. Radiat. Isot. 94, 44 (2014), 10.1016/j.apradiso.2014.07.003] for the photon energy regions 0.025 ≤ω ≤0.150 MeV and 0.001 ≤ω ≤0.100 MeV , respectively.

  1. Metal-Semiconductor Interfaces and Patterns in Functionalized Graphene

    NASA Astrophysics Data System (ADS)

    Singh, Abhishek; Penev, Evgeni; Yakobson, Boris

    2010-03-01

    Functionalization offers a novel way to modify the electronic and magnetic properties of graphene. Specific topology is essential to achieve devices with the desired features. Using density functional theory, we demonstrate stability of several such configurations, (in single and double sided functionalized graphene) and analyze their electronic and magnetic properties. We show that ``nanoroads'' [1] and ``nanodots'' [2] of pristine graphene can be carved in the electrically insulating matrix of fully hydrogenated carbon sheet (graphane) [1]. Such one-dimensional roads display individual characteristics and, depending upon zigzag or armchair orientation, can be metallic or semiconducting. Furthermore, the wide enough zigzag roads become magnetic with energetically similar ferro- and antiferromagnetic states. Engineering magnetic, metallic, and semiconducting elements within the same mechanically intact sheet of graphene presents a new opportunity for applications. [1] A. K. Singh and B. I. Yakobson, Nano Lett., 9, 1540 (2009). [2] A. K. Singh, E. S. Penev, and B. I. Yakobson submitted.

  2. Nonlinear study of seismicity in the Mexican subduction zone by means of visual recurrence analysis

    NASA Astrophysics Data System (ADS)

    Ramirez Rojas, A.; Moreno-Torres, R. L.

    2012-12-01

    The subduction in the Mexican South Pacific coast might be approximated as a subhorizontal slab bounded at the edge by the steep subduction geometry of the Cocos plate beneath the Caribbean plate to the east and of the Rivera plate beneath North America to the west. Singh et al. (1983), reported a study that takes into account the geometry of the subducted Rivera and Cocos plates beneath the North American lithosphere defining, according their geometry, four regions: Jalisco, Michoacán, Guerrero and Oaxaca. In this work we study the seismicity occurred in Mexico, for each region, by means of the visual recurrence analysis (VRA). Our analysis shows important differences between each region that could be associated with nonlinear dynamical properties of each region. Singh, S.K., M. Rodriguez, and L. Esteva (1983), Statistics of small earthquakes and frequency of occurrence of large earthquakes along the Mexican subduction zone, Bull. Seismol. Soc. Am. 73, 6A, 1779-1796.

  3. Pattern classification using maximally entangled quantum states (MES)

    NASA Astrophysics Data System (ADS)

    Singh, Manu Pratap; Rajput, B. S.

    2014-04-01

    Pattern classifications have been performed by employing the method of Grover's iteration on Bell's MES and Singh-Rajput MES in a two-qubit system and it has been demonstrated that, for any pattern classification, in a two-qubit system the maximally entangled states of Singh-Rajput eigenbasis provide the most suitable choice of search states while, in no case, any of Bell's states is suitable for such pattern classifications. Applying the method of Grover's iterate on three different superpositions in a three-qubit system, it has been shown that the choice of exclusive superposition, as the search state, is the most suitable one for the desired pattern classifications based on Grover's iterative search algorithm.

  4. Do OSCAR winners live longer than less successful peers? A reanalysis of the evidence.

    PubMed

    Sylvestre, Marie-Pierre; Huszti, Ella; Hanley, James A

    2006-09-05

    In an article published in Annals of Internal Medicine in 2001, Redelmeier and Singh reported that Academy Award-winning actors and actresses lived almost 4 years longer than their less successful peers. However, the statistical method used to derive this statistically significant difference gave winners an unfair advantage because it credited an Oscar winner's years of life before winning toward survival subsequent to winning. When the authors of the current article reanalyzed the data using methods that avoided this "immortal time" bias, the survival advantage was closer to 1 year and was not statistically significant. The type of bias in Redelmeier and Singh's study is not limited to longevity comparisons of persons who reach different ranks within their profession; it can, and often does, occur in nonexperimental studies of life- or time-extending benefits of medical interventions. The current authors suggest ways in which researchers and readers may avoid and recognize this bias.

  5. The California Central Coast Research Partnership: Building Relationships, Partnerships, and Paradigms for University-Industry Research Collaboration

    DTIC Science & Technology

    2011-03-28

    production of microalgae-based biofuels in closed-loop tubular photobioreactors and microalgae production in a vertical photobioreactor. Ilhami...Burd, D.V.M. 394 Assessment of single-use cold-chain packaging and logistics for temperature sensitive products . Jay Singh, Ph.D., Industrial...health. Michael W. Black, Ph.D., Biological Sciences 433 Extended shelf-life, performance-enhancing, dairy-based food products for the warfighter

  6. Impact of NiB Coating on the Efficiency, Scuffing, and Wear of Gear Contacts

    DTIC Science & Technology

    2013-05-01

    dependent (mechanical) power losses. This was confirmed by Talbot et al. (11) through planetary gear -set power-loss experiments as well. Some of...ground or shaved surfaces. Gear experiments (4, 5, 8, 14) show sizable reductions in spur or planetary gear -mesh mechanical power losses of shaved...D.; Kahraman, A.; Singh, A. An Experimental Investigation of the Efficiency of Planetary Gear Sets. Journal of Mechanical Design 2012, 134 (2

  7. A Kinematic Study of the Merlin 6500 Robot and the UTAH/MIT Dexterous Hand and a Simulation of their Combined Behavior

    DTIC Science & Technology

    1988-09-01

    OF THEIR COMBINED BEHAVIOR (UNCLASSIFIED) 12 . PERSONAL AUTHOR(S) Ranvir Singh Solanki and Kuldip S. Rattan, Wright State University 13a. TYPE OF... 12 The lathematics of Transformation Operators 13 MANIPULATOR KINEMATICS 16 Joint Description 16 Types of lanipulator Joints 16 Significant...Merlin 6500 Horizontal Plane Workspace 65 12 . The Utah/MIT Dexterous Hand Frame Assignments - Top View 67 13. The Utah/KIT Dexterous land Frame

  8. Holocene Depositional History of the Southern New Jersey Barrier and Backbarrier Regions

    DTIC Science & Technology

    1990-02-01

    earlier identified and described by Klein (1977) and 23 Reinleck and Singh (1980). Macrofauna are usually present and include Crassostrea virginica ...substrate. 2110 BP ’, 15 Crassostrea virginica zone of mostly fragmented shells. 5 Cressostrea virginica zone with whole and fragmented shells. Fluvial 1-3...clean sand zone . Scattered organics from 5.2-5.4 a. _ -10 ; Unit becomes cleaner with depth. 95:02:03 00:02:98 6 -120 Crassostrea virginica in

  9. Estimating an Image’s Blur Kernel from Edge Intensity Profiles

    DTIC Science & Technology

    2012-08-01

    B. Singh, A. Hertzmann, S.T. Roweis, and W.T. Freeman “ Removing camera shake from a single photograph ”, SIGGRAPH, 2006. [8] Taeg S. Cho, Sylvain...Estimation for Image Deblurring”, CVGIP: Graphical Models and Image Processing, Vol. 53, No. 4, pp. 364-372, 1991. [14] Azriel Rosenfeld, Avinash Kak, Digital ...of observed distributions”, Journal of Astronomy , Volume 79, number 6, pages 745-754, 1974. [21] L. Yuan, J. Sun, L. Quan,H. Shum, “Progressive

  10. The JWKB approximation in loop quantum cosmology

    NASA Astrophysics Data System (ADS)

    Craig, David; Singh, Parampreet

    2017-01-01

    We explore the JWKB approximation in loop quantum cosmology in a flat universe with a scalar matter source. Exact solutions of the quantum constraint are studied at small volume in the JWKB approximation in order to assess the probability of tunneling to small or zero volume. Novel features of the approximation are discussed which appear due to the fact that the model is effectively a two-dimensional dynamical system. Based on collaborative work with Parampreet Singh.

  11. Engineering of Sensor Network Structure for Dependable Fusion

    DTIC Science & Technology

    2014-08-15

    Transient Time Series for Fault Detection in Gas Turbine Engines, Journal of Dynamic Systems , Measurement, and Control, (01 2013): 0. doi: 10.1115...China. : , Soumik Sarkar, Dheeraj S. Singh, Abhishek Srivastav, Asok Ray. Semantic Sensor Fusion for Fault Diagnosis in Aircraft Gas Turbine...2. Online void fraction measurement in two phase flow systems via nonlinear filtering of ultrasonic signals (Dr. Ray, PSU) 3. Diagnosis and

  12. Isolation of Breast Tumor Suppressor Genes from Chromosome 11p

    DTIC Science & Technology

    2001-09-01

    at chromosome crucial role in urogenital development (Pelletier et al., llp15 has also been described in Wilms tumors but thus 1991). However...Atkins L and Riccardi VM. (1979). Nowak NJ, Evans G, Stanbridge EJ, de Jong P, Shows TB , Cytogenet. Cell Genet., 24, 185-192. Weissman BE and Higgins MJ...Singh-Kahlon P, Weksberg R, Squire J, Grundy P, Coppes MJ and Haber D. (1995). Hematology/ Shows TB and Higgins MJ. (1994). Genes Chromosomes Oncology

  13. Reversal of Doxorubicin Resistance in Human Breast Adenocarcinoma (MCF-7) Cells by Liposomal Monensin

    DTIC Science & Technology

    2005-06-01

    drugs. J. Pharin. Pharinacal. 53: 617--627 lial Caco - 2 cell layers and everted gut sacs of rats. Biocheja. Shaik, M. S., Kanikkasnnan, N.. Singh. M. (201...Intralipid on the transport of cpirubicin in Caco - 2 cells throwugh stealth nanoparticles and liposomrcs. .4APS Pliarin and rat intestines. J. Conitrolled...PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 2 . REPORT TYPE 3. DATES COVERED (From - To) 01-06-2005 Annual Summary

  14. When Diversity Training Isn’t Enough: The Case for Inclusive Leadership

    DTIC Science & Technology

    2013-08-06

    perceptions of organizational justice have myriad outcomes for employees. Procedural justice has been positively related to employees’ self - perceived...Singh (2001) define inclusion as “the degree to which an employee perceives that he or she is an esteemed member of the work group through experiencing...career motivation and self -efficacy with protégé career success. Journal of Vocational Behavior, 64, 72–91. DeConinck, J. B., & Johnson, J. T. (2009

  15. Core Logistics Capability Policy Applied to USAF Combat Aircraft Avionics Software: A Systems Engineering Analysis

    DTIC Science & Technology

    2010-06-01

    PROJECT Presented to the Faculty Department of Systems and Engineering Management Graduate School of Engineering and Management Air Force...a light grey box around the definitions. This table, a fit-for-purpose architecture product , is loosely based on the DoD Architecture Framework ...synopsis of ISO/IEC 12207, Raghu Singh of the Federal Aviation Administration states “Whenever a software product needs modifications, the development

  16. Terrorism in Southeast Asia

    DTIC Science & Technology

    2009-10-16

    Specialist in Asian Affairs Emma Chanlett-Avery Specialist in Asian Affairs Ben Dolven Section Research Manager Mark E. Manyin Specialist in Asian...Asia 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...those terrorists and militants who would also use violence, or the threat of violence, to promote such a cause. 2 Daljit Singh ,”The Terrorist Threat

  17. Lipoid Proteinosis

    PubMed Central

    Yadav, Sunil; Malik, Sunita; Singh, Gurdarshan

    2016-01-01

    ABSTRACT A case report of a 6-year-old male child who reported with recurrent oral and skin ulcerations since childhood and was diagnosed as lipoid proteinosis manifesting with generalized thickening, hardening, and scarring of the skin and hoarseness of voice; is presented here. How to cite this article: Mittal HC, Yadav S, Malik S, Singh G. Lipoid Proteinosis. Int J Clin Pediatr Dent 2016;9(2):149-151. PMID:27365938

  18. Research and Development Strategies for the Current and Future Medical Treatment of Radiation Casualties

    DTIC Science & Technology

    2014-09-01

    include the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute for Allergies and Infectious Diseases (NIAID...Twenty Years of G-CSF: Clinical and Nonclinical Discoveries, ed. G. Molineux, M. Foote , and T. Arvedson (Basel: Springer, 2012). 39 V. K. Singh et al...1980s. For a review see K. Welte, “Discovery of G-CSF and Early Clinical studies,” in Twenty Years of G-CSF, ed. G. Molineux, M. Foote , and T

  19. EnSight Volume Visualization

    DTIC Science & Technology

    2012-11-01

    R L DONEY G VUNNI B VONK RDRL WMP C R B LEAVY M N RAFTENBERG RDRL VTV S ARAM R K SINGH 18 INTENTIONALLY LEFT BLANK. ...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Richard C. Angelini 5d. PROJECT NUMBER R .0000551.1 5e. TASK...100 × 100 × 100 structured mesh (e) 250 × 250 × 250 structured mesh ( f ) 500 × 500 × 500 structured mesh 6

  20. Reflections from a Year at the Center for Global Health

    Cancer.gov

    The Cancer Research Training Award (CRTA) Fellowship is a one-year fellowship, where a laboratory, a Center or a Division within the National Cancer Institute takes in a post baccalaureate trainee for a year. This trainee is typically someone who has completed their Bachelor’s degree and is ready to put their knowledge into useful action as they chart out their career and future education. After a year, CRTA Fellow, Tulika Singh reflects on her year of service.

  1. A Survey of Mobile and Wireless Technologies for Augmented Reality Systems (Preprint)

    DTIC Science & Technology

    2008-02-01

    Page 1 of 30 A survey of mobile and wireless technologies for augmented reality systems George Papagiannakis*, Gurminder Singh**, Nadia...performance of the current task, enabling an “ Augmented Reality ” (AR) Caudell et al [2]. Although AR was meant to include mobility, it was not until...The Columbia Touring Machine” by Feiner et al [3] that the first outdoor Mobile Augmented Reality System (MARS) was created. Around the same time

  2. Morphological redescription and molecular characterization of three species of Travassosinematidae (Nematoda: Oxyurida: Thelastomatoidea) from Gryllotalpa africana Beauv (Orthoptera: Gryllotalpidae).

    PubMed

    Singh, Neetu; Chaudhary, Anshu; Singh, Hridaya Shanker

    2013-01-01

    Binema mirzaia (Basir, 1942a) Basir, 1956, Cameronia nisari (Parveen and Jairajpuri, 1985) Adamson and Van Waerebeke, 1992a and Mirzaiella meerutensis Singh and Malti, 2003 are redescribed morphologically along with molecular identification from the intestine of mole cricket Gryllotalpa africana. Molecular characterization was carried out using the D2-D3 expansion domains of the 18S ribosomal DNA region. This study first time presents molecular data for the above three nematode species.

  3. Propagation and Excitation of Lg, Sn, and P-Pn Waves from Eastern United States Earthquakes by Regression Analysis of RSTN Data. Seismic Attenuation Studies at United Kingdom Arrays

    DTIC Science & Technology

    1987-05-01

    and Sn dominate. Seismo- grams of similar nature have also been observed in eastern Canada (Shin 1985, Shin and Herrmann 1987) and at NORESS over...Canada, Lg experiences significant contamination from Sn coda (Shin 1985, Chun et al 1987, Shin and Herrmann 1987). This is suggested by the way that...surface wave data (Mitchell 1981). Other set of numbers comes from coda Q studies (Singh and Herrmann 1983). Finally, a smaller set of results comes

  4. Revision of the genus Kailasha (Lepidoptera, Erebidae, Arctiinae) from Oriental region, with description of one new species.

    PubMed

    Ulziijargal, Bayarsaikhan; Na, Sol-Moon; Bae, Yang-Seop

    2017-01-03

    The genus Kailasha Singh & Kirti of Erebidae in Oriental Region is reviewed, with six species including a new species, Kailasha babensis Bae & Bayarsaikhan, sp. n., which is closely similar to effracta group in the superficial characters. Two species, K. pellucida (Rothschild), comb. n. and K. angkorensis Bayarsaikhan & Bae, comb. n., are newly combined from the genus Cyana Walker. Brief descriptions on all known species, with illustrations of adults and both sexes of genitalia are provided. A key to species is given.

  5. News and Views: Where at a supermassive black hole do gamma-rays come from? Keep libel laws out of science

    NASA Astrophysics Data System (ADS)

    2009-08-01

    Radio observations of galaxy M87 at the time of a massive gamma-ray flare have established that the gamma-ray emission arises close to the central black hole, in the inner jet. Writer Simon Singh is being sued for libel by the British Chiropractic Association because he wrote a newspaper article about the evidence for the effectiveness of spinal manipulation as a treatment for childhood illnesses. Why should scientists care about this action, asks Sue Bowler?

  6. COMPOSITE CERAMIC ARMOR DEFECT ANALYSIS USING PHASED ARRAY ULTRASOUND

    DTIC Science & Technology

    2011-01-30

    background variation. Such an approximation applied to the FFT results of Conclusion Phased - array ultrasonic inspection methods have been...SNR values above 2.55) were statistically defective either. CONCLUSION Phased - array ultrasonic inspection methods have been successfully applied to...4 G.P. Singh and J. W. Davies, “Multiple Transducer Ultrasonic Techniques: Phased Arrays ” In Nondestructive Testing Handbook, 2nd Ed., 7, pp. 284

  7. Design and Synthesis of Substituted Cyclopropanes as Conformationally Restrained Dipeptide Mimics.

    DTIC Science & Technology

    1992-05-01

    M .; Cramer, R . D .; Opdenbosch, N. V. J . Comp. Chem. 1989, 8, 982. (b) Weiner, S . J .; Kollman, P. A.; Case, D . A.; Singh, U . C .; Ghio, C .; Alagona...Darke, P. L.; Diccarone, T. M .; Colton, C . D .; Rodkey, J . A.; Bennet, C . D .; Waxman, L. N.; Sigal, 1. S . Proc. Nati. Acad. Sci. U . S . A. 1988, 8S, 7129...Heinrikson, R . L.; Tomick, C . C . Biochemistry

  8. Between Hope and Fear: The Psychology of Risk.

    DTIC Science & Technology

    1986-05-01

    further away at the high end (striped area upper right). Thus, the riskless lottery offers both higher minima and higher maxima. Not surprisingly, it...probability theory. Historia Mathematica, 7, 234-260. Day, R. H. (1979). Cautious suboptimizing. In J. A. Roumasset, J.-M. Boussard, & I. Singh (Eds...Alexandria, VA 22311 6 .- . JANUARY 1986 Other Organizations Dr. David Van Essen Dr. Stanley N. Roscoe California Institute of Tech. New Mexico State

  9. Dynamic Data Driven Applications Systems (DDDAS)

    DTIC Science & Technology

    2013-03-06

    of a spinning blade 2. Detected significant changes in the stress levels in the region with defect 3. Refined mesh, re-interpolated solution and...that is dynamically updated? Challenges I Possible Solutions How to e nsure correctness and completeness of dynamically updated workflows? Atomic... Volcanic Ash Transport & Dispersal Forecast A. Patra, M. Bursik, E. B. Pitman, P. Singla, T. Singh, M. Jones – Univ at Buffalo; M. Pavolonis Univ

  10. Dynamic Data Driven Applications Systems (DDDAS)

    DTIC Science & Technology

    2012-05-03

    Swarms Research Test-Bed Synthetic UAV SwarmDDDAS Simulation of UAV Swarm Challenges / Possible Solutions How to ensure correctness and consistency in...Unlimited Distribution DDDAS Approach To Volcanic Ash Transport & Dispersal Forecast A. Patra, M. Bursik, E. B. Pitman, P. Singla, T. Singh, M. Jones...Univ at Buffalo; M. Pavolonis Univ. Wisconsin/NOAA; B. P. Webley, J. Dehn – Univ Alaska Fairbanks; A. Sandu Virginia Tech Solution : Provide

  11. Agent Based Modeling and Simulation Framework for Supply Chain Risk Management

    DTIC Science & Technology

    2012-03-01

    timed Petri net based simulation (Tuncel and Alpan 2010), and Monte Carlo (White 1995, Wu and Olson 2008, and Schmitt and Singh 2009). More detail...benefit costs. (Li and Li 2008) 26 Chen, Zhou, and Hu propose an agent-oriented Petri net model for an inventory- scheduling model, with focus on the...problems of analysis and modeling of multi-agent systems. Petri net aims at researching the organization structure and dynamic behavior of a system

  12. Can Exosomes Induced by Breast Involution Be Markers for the Poor Prognosis and Prevention of Postpartum Breast Cancer

    DTIC Science & Technology

    2015-07-01

    87-98 8. Schedin P: Pregnancy-associated breast cancer and metastasis, Nature reviews 2006, 6:281- 291 9. Schedin P, Strange R, Mitrenga T, Wolfe P... review and audit by the University of Colorado Cancer Center Data Safety Monitoring Committee through the approved parent protocols from which the...Schedin P: Pregnancy-associated breast cancer and metastasis, Nature reviews 2006, 6:281-291 39. Singh-Ranger G, Salhab M, Mokbel K: The role of

  13. Health Risk Assessment of Women in Submarines (Phase III): Two Generation Developmental and Reproductive Safety Evaluation of Major Submarine Atmosphere Components (CO, CO2, and O2) in Rats (Rattus norvegicus)

    DTIC Science & Technology

    2012-05-31

    Mukherjee and Singh, 1967); decreased fetal viability and increased heart malformations in rats at 6% CO2 (Haring, 1960); and, neurobehavioral deficits...Hochrainer, 1977); 11 decreased splenic macrophage function in rats at 75 ppm (Giustino et al., 1993); skeletal malformations in mice at 250 ppm...gross malformations . This current report (Phase 3) describes the results of a modified 90-day, two generation, sub-chronic study modeled after U.S

  14. National Guard Posture Statement 2010. America’s Indispensable Force

    DTIC Science & Technology

    2010-01-01

    Shane A. Cuomo Staff Sergeant Justin Goeden Staff Sergeant Jim Greenhill Technical Sergeant Erik Gudmundson Staff Sergeant Russell L. Klika Technical...W. Clemons, KY SGT Russell L. Collier, AR SFC Kurt J. Comeaux, LA SPC Anthony S. Cometa, NV SGT Brian R. Conner, MD SFC Sean M. Cooley, MS SSG Travis...Sietsema, IL SGT Alfred B. Siler, TN SGT Alfredo B. Silva, CA SGT Isiah J. Sinclair, LA SPC Roshan (Sean) R. Singh, NY SPC Channing G. Singletary, GA

  15. International Laser Radar Conference (16th) held at the Massachusetts Institute of Technology, Cambridge, Massachusetts on 20-24 July 1992. Part 1

    DTIC Science & Technology

    1993-07-24

    Perspectives Giorgo Fiocco 9:30-11:45 SESSION A: Volcanic (Mt. Pinatubo) Dust Layer Measurements Session Chair: Allan Carswell 9:30 Al (Invited) Long...Whiteman, and K. D. Evans 11:30 A6 Lidar Observations of Stratospheric Aerosol Layer After the Mt. Pinatubo Volcanic Eruption...Presence of Volcanic Aerosols ..................................... 31 Upendra N. Singh, Thomas J. McGee, Michael Gross, William S. Heaps, and Richard

  16. JPRS Report, Near East & South Asia.

    DTIC Science & Technology

    1989-03-08

    Barisal, Faridpur and Kush- tia belong to his state to be domiciled by people who had left Bangladesh after the partition of British India in 1947...words and deeds was no follower of Jinnah but of Maulana Maudoodi. Mian Nawaz Sharif, in his zeal to emerge as a national leader had, in a League...be necessary to first examine if there has ever been a Punjabi nation. Historically the pre- partition Punjab was carved out by Ranjit Singh after

  17. Mechanism(s) of Molecular Responses in Mammalian Cells Exposed to Physical Agents (Alone and in Combination).

    DTIC Science & Technology

    2007-11-02

    The bone marrow 26. H. Lai and N. P. Singh, Acute low-intensity microwave exposure micronucleus test . In Handbook of Mutageniciu Test Procedures (B. J...210 (1995). Elsevier. Amsterdam, 1984. 27 T. Sofuni. Japanese guidelines for mutagenicity testing . Environ. 33. W. Schmid, The micronucleus test ...L. Dearfield and M. C. Cimino. Mutagenicity test spontaneous micronucleus frequencies. Environ. MoL Mutagen. 23, schemes and guidelines: U.S. EPA

  18. A Survey of Large High-Resolution Display Technologies, Techniques, and Applications

    DTIC Science & Technology

    2006-03-01

    and et al. Shared display wall based collaboration environment in the control room of the DIII-D national fusion facility. In WACE , 2005. [2] Alias...collaborative classroom learning environment. In WACE , 2005. [74] S. Molnar, M. Cox, D. Ellsworth, and et al. A sorting classification of parallel rendering. IEEE...Last accessed December 18, 2005. [96] L. Renambot, A. Rao, R. Singh, and et al. Sage: the scalable adaptive graphics environment. In WACE , 2004. [97] M

  19. Nanoengineered Carbon-Based Materials For Reactive Adsorption of Toxic Industrial Compounds

    DTIC Science & Technology

    2015-01-13

    Mendoza, T.J. Bandosz. Reactive adsorption of ammonia on Cu-based MOF /graphene composites , Langmuir, (7 2010): . doi: Kavindra Singh, Nikolina A...graphite oxide composites on the adsorption of ammonia , Journal of Colloid and Interface Science, (03 2014): 0. doi: 10.1016/j.jcis.2013.11.010... ammonia on graphene/nanoporous carbon composites, Carbon, (4 2013): 0. doi: 10.1016/j.carbon.2012.12.024 Oluwaniyi Mabayoje, Mykola Seredych, Teresa

  20. GaAs High Breakdown Voltage Front and Back Side Processed Schottky Detectors for X-Ray Detection

    DTIC Science & Technology

    2007-11-01

    currently available SI GaAs materials. This work deals with the fabrication of SI GaAs wafers with front and back end processing for Schottky and...GaAs High Breakdown Voltage Front and Back Side Processed Schottky Detectors for X-ray Detection by Fred Semendy, Satpal Singh, Mark Litz...originator. Army Research Laboratory Adelphi, MD 20783-1197 ARL-TR-4308 November 2007 GaAs High Breakdown Voltage Front and Back

  1. Mechanisms Related to Different Generations of gamma’ Precipitation During Continuous Cooling of a Nickel Base Superalloy

    DTIC Science & Technology

    2012-04-01

    during continuous cooling of a nickel base superalloy A.R.P. Singh a , S. Nag a , S. Chattopadhyay b ,c, Y. Ren f, J. Tiley d, G.B. Viswanathan d, H.L...ABSTRACT: SAR 18. NUMBER OF PAGES 18 19a. NAME OF RESPONSIBLE PERSON (Monitor) Jaimie Tiley a . REPORT Unclassified b . ABSTRACT...superlattice, and ( b ) (111) fundamental reflections arising from both c and c0 phases as a function of temperature during slow continuous cooling of Rene

  2. Mechanisms of Precipitation of Different Generations of Gamma-Prime Precipitates During Continuous Cooling of a Nickel Base Superalloy (PREPRINT)

    DTIC Science & Technology

    2012-08-01

    LIMITATION OF ABSTRACT: SAR NUMBER OF PAGES 34 19a. NAME OF RESPONSIBLE PERSON (Monitor) a . REPORT Unclassified b . ABSTRACT Unclassified...Superalloy A . R. P. Singh1, S. Nag1, S. Chattopadhyay2, Y. Ren2, J. Tiley3, G. B . Viswanathan3, H. L. Fraser4, and, R. Banerjee1 1Center for...Fig. 1. Fig. 1( a ) and ( b ) show the progressive change in the Approved for public release; distribution unlimited 6 intensity of the (001) γ

  3. A re-examination of impulsive VLF signals in the night ionosphere of Venus

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Singh, R. N.

    1989-01-01

    Consideration is given to the impulsive electrical signals clustered around periapsis which were observed by the Pioneer Venus Orbiter Electric Field Detector. The study of these signals by Singh and Russell is repeated, taking into account the telemetry errors noted by Taylor and Cloutier (1988). It is found that there is naturally occurring noise in the dark ionosphere of Venus near periapsis. The absolute rates of occurrence are determined, showing differences with the results from the original study.

  4. An Invitation to Imitation

    DTIC Science & Technology

    2015-03-15

    their deep insight into the key differences between supervised and imitation learning . Consider a smaller, simplified version of the problem...B Tenenbaum. Action understanding as inverse planning. Cognition, 113(3):329–349, 2009. Y. Bengio. Learning deep architectures for AI. Foundations and...International Conference on Machine Learning . X. Guo, S. Singh, H. Lee, R. L Lewis, and X. Wang. Deep learning for real- time atari game play using offline

  5. Studying recombination with high-throughput sequencing: an educational primer for use with "fine-scale heterogeneity in crossover rate in the garnet-scalloped region of the Drosophila melanogaster X chromosome".

    PubMed

    Heil, Caiti S Smukowski; Noor, Mohamed A F

    2013-06-01

    An article by Singh and colleagues in this issue of GENETICS quantifies variation in recombination rate across a small region of the Drosophila melanogaster genome, providing an opportunity for instructors of genetics to introduce or reinforce important concepts such as recombination and recombination rate variation, genome sequencing, and sequence features of the genome. Additional background information, a detailed explanation of the methods used in this study, and discussion questions are provided.

  6. Heteroepitaxial Growth and Doping of ZnO for Optoelectronic Applications

    DTIC Science & Technology

    2005-08-19

    synthesis and characterization of highly monodisperse transition metal doped ZnO nanoparticles," S.P. Singh, 0. Prealez...presented in MRS fall meeting, Nov.29-Dec.3, (2004). 9. " Synthesis and characterization of ZnO and Mn- ZnO nanocrystals for spintronic applications... synthesis of Mn doped ZnO was performed by a solution process at room temperature. This route is based on dehydration properties of

  7. Study of growth of dot and column in porous silicon samples of various thicknesses prepared at a constant current density

    NASA Astrophysics Data System (ADS)

    Gill, Fateh Singh; Panwar, Varij; Gupta, Himanshu; Kalra, G. S.; Chawla, Shanta; Kumar, R.; Mehra, R. M.

    2015-09-01

    Porous silicon is considered to be composed either of spherical shaped interconnected silicon quantum dots or combination of quantum dots and columns. This paper presents a study of a series of porous silicon films of various thicknesses, prepared at a 20 mA current density by the electrochemical etching technique. The photoluminescence spectra of the series samples were monitored. Further, we used a photoluminescence fitting model by Singh and John (John-Singh) in its extended form by Elhouichet to estimate the percentage of dots and columns; their average diameters and corresponding variances. The shape of experimental photoluminescence spectra fits well with John-Singh model. As a result, the analytical curves drawn using the fitting parameters showed the decrease in mean crystallite diameter of columns and dot while increase in variance of column and decrease in variance of dots. Hence, more homogenous dots are formed. Thus, it results in the formation of a more ordered nanocrystalline structure with more porosity. It verified the quantum assumptions. The discrepancy in the PL behavior of a sample is well explained by the model.

  8. Nuclear electric quadrupole moment of potassium from the molecular method

    NASA Astrophysics Data System (ADS)

    Teodoro, Tiago Quevedo; Haiduke, Roberto Luiz Andrade; Visscher, Lucas

    2015-03-01

    The current standard nuclear quadrupole moments (NQMs) of the 39K , 40K , and 41K isotopes have recently been contested by Singh and co-workers on the basis of their atomic computational data [Singh et al., Phys. Rev. A 86, 032509 (2012), 10.1103/PhysRevA.86.032509]. Thus we performed relativistic calculations of electric field gradients at the potassium nuclei in three diatomic molecules (KF, KCl, and KBr) and combined these values with accurate experimental nuclear quadrupole coupling constants to provide an independent assessment of these NQMs. Our most accurate results, obtained by treating electron correlation with coupled cluster theory, employing a four-component Hamiltonian that includes the Gaunt two-electron correction, and with an incremented relativistic basis set of quadruple-ζ quality, yield Q (39K)=60.3 (6 ) , Q (40K)=-75.0 (8 ) , and Q (41K)=73.4 (7 ) mb . These values are in better agreement with the results obtained by Singh et al. and indicate that the standard NQMs should be revised.

  9. Role of Annexin-II in GI cancers: interaction with gastrins/progastrins.

    PubMed

    Singh, Pomila

    2007-07-08

    The role of the gastrin peptide hormones (G17, G34) and their precursors (progastrins, PG; gly-extended gastrin, G-gly), in gastrointestinal (GI) cancers has been extensively reviewed in recent years [W. Rengifo-Cam, P. Singh, Role of progastrins and gastrins and their receptors in GI and pancreatic cancers: targets for treatment, Curr. Pharm. Des. 10 (19) (2004) 2345-2358; M. Dufresne, C. Seva, D. Fourmy, Cholecystokinin and gastrin receptors, Physiol. Rev. 86 (3) (2006) 805-847; A. Ferrand, T.C. Wang, Gastrin and cancer: a review, Cancer Lett. 238 (1) (2006) 15-29]. A possible important role of progastrin peptides in colon carcinogenesis has become evident from experiments with transgenic mouse models [W. Rengifo-Cam, P. Singh, (2004); A. Ferrand, T.C. Wang, (2006)]. It is now known that growth stimulatory and co-carcinogenic effects of gastrin/PG peptides are mediated by both proliferative and anti-apoptotic effects of the peptides on target cells [H. Wu, G.N. Rao, B. Dai, P. Singh, Autocrine gastrins in colon cancer cells Up-regulate cytochrome c oxidase Vb and down-regulate efflux of cytochrome c and activation of caspase-3, J. Biol. Chem. 275 (42) (2000) 32491-32498; H. Wu, A. Owlia, P. Singh, Precursor peptide progastrin(1-80) reduces apoptosis of intestinal epithelial cells and upregulates cytochrome c oxidase Vb levels and synthesis of ATP, Am. J. Physiol. Gastrointest. Liver Physiol. 285 (6) (2003) G1097-G1110]. Several receptor subtypes have been described that mediate growth effects of gastrin peptides [W. Rengifo-Cam, P. Singh (2004); M. Dufresne, C. Seva, D. Fourmy, (2006)]. Recently, we identified Annexin II as a high affinity binding protein for gastrin/PG peptides [P. Singh, H. Wu, C. Clark, A. Owlia, Annexin II binds progastrin and gastrin-like peptides, and mediates growth factor effects of autocrine and exogenous gastrins on colon cancer and intestinal epithelial cells, Oncogene (2006), doi:10.1038/sj.onc.1209798]. Importantly, the expression of

  10. Hierarchical resilience with lightweight threads.

    SciTech Connect

    Wheeler, Kyle Bruce

    2011-10-01

    This paper proposes methodology for providing robustness and resilience for a highly threaded distributed- and shared-memory environment based on well-defined inputs and outputs to lightweight tasks. These inputs and outputs form a failure 'barrier', allowing tasks to be restarted or duplicated as necessary. These barriers must be expanded based on task behavior, such as communication between tasks, but do not prohibit any given behavior. One of the trends in high-performance computing codes seems to be a trend toward self-contained functions that mimic functional programming. Software designers are trending toward a model of software design where their core functions are specified in side-effect free or low-side-effect ways, wherein the inputs and outputs of the functions are well-defined. This provides the ability to copy the inputs to wherever they need to be - whether that's the other side of the PCI bus or the other side of the network - do work on that input using local memory, and then copy the outputs back (as needed). This design pattern is popular among new distributed threading environment designs. Such designs include the Barcelona STARS system, distributed OpenMP systems, the Habanero-C and Habanero-Java systems from Vivek Sarkar at Rice University, the HPX/ParalleX model from LSU, as well as our own Scalable Parallel Runtime effort (SPR) and the Trilinos stateless kernels. This design pattern is also shared by CUDA and several OpenMP extensions for GPU-type accelerators (e.g. the PGI OpenMP extensions).

  11. In vitro evaluation of different varieties of maize fodder for their methane generation potential and digestibility with goat rumen liquor

    PubMed Central

    Vaswani, Shalini; Kumar, Ravindra; Kumar, Vinod; Roy, Debashis; Kumar, Muneendra

    2016-01-01

    Aim: To evaluate the methane generation potential and digestibility of different (normal and three high-quality protein maize [HQPM]) varieties of maize fodder with goat rumen liquor in vitro. Materials and Methods: Methane production potential and digestibility of different varieties of maize fodder were tested in in vitro gas production test. Seven varieties of maize, four normal (HTHM 5101, DHM 117, HM 5, and Shaktiman/900 M Gold), and three high-quality protein (HQPM 5, HQPM 7, and HQPM 9/Vivek) were grown in different plots under the same environmental and agro-climatic conditions. Fodders were harvested at 45-50 days of sowing, and the representative samples of fodder from different varieties of maize were collected for analysis. Dried and grinded form of these maize fodder varieties was tested for gas, methane, and digestibility using goat rumen microflora in in vitro gas syringes. Results: Gas production (ml/g dry matter [DM]) was highest for HM5 variety (97.66, whereas lowest for HQPM 9 variety (64.22). Gas production (ml/g degraded DM [DDM]) and methane (%) were statistically similar in different varieties of maize fodder. The methane production expressed as ml/g DM and ml/g DDM was significantly (p<0.05) highest for HM 5 (14.22 and 26.62) and lowest for DHM 117 variety (7.47 and 14.13). The in vitro DM digestibility (%) and in vitro organic matter digestibility (%) varied from 47.48 (HQPM 5) to 52.05 (HQPM 9) and 50.03 (HQPM 7) to 54.22 (HM 5), respectively. Conclusion: The present study concluded that DHM 117 maize variety fodder has lowest methane generation potential and incorporating it in the dietary regime of ruminants may contribute to lower methane production. PMID:27956770

  12. Classification of Interdental Space for Different Quadrants on the Basis of Standardization through Threshold Data and Its Comparison with BMI and Socioeconomic Status

    PubMed Central

    Singh, Ronauk; Singh, Jatinder Pal

    2013-01-01

    ABSTRACT Background: A better knowledge about the Interdental space is important since it provides insights on the prevalence of malocclusion. To date, there is conflicting evidence on the impact of body mass index (BMI) and Socioeconomic status (SES) on interdental space. A recent review concluded that a greater understanding is required of the interdental space. Therefore, there is a need for a more comprehensive and rigorous assessments of the interdental space and impacts of BMI and SES. Aim: BMI and SES can be associated with the interdental spacing in deciduous dentition. Design: The present cross-sectional study was carried out on 448 children of age group of 3 to 5 years out of which 392 were meeting our criteria. Research assessment questionnaire on demographic data was completed by the parents. Study model cast of 392 children free from malocclusion were analyzed. Results: A statistically significant association between interdental spacing and BMI category was observed. Comparison of BMI with above threshold interdental space revealed that after an optimum weight there is no effect on interdental space. A significant association between SES and interdental spacing was observed for all the four locations (p < 0.01). Conclusion: Evolved normative value can be taken as a standard and the occlusion and interdental spaces are not two completely separate entities and they are interdependent. How to cite this article: Singh T, Singh R, Singh JP. Classification of Interdental Space for Different Quadrants on the Basis of Standardization through Threshold Data and Its Comparison with BMI and Socioeconomic Status. Int J Clin Pediatr Dent 2013;6(1):16-21. PMID:25206181

  13. Nuclear Data Sheets for A = 152

    SciTech Connect

    Martin, M.J.

    2013-11-15

    Detailed level schemes, decay schemes, and the experimental data on which they are based are presented for all nuclei with mass number A=152. The experimental data are evaluated; inconsistencies and discrepancies are noted; and adopted values for level and γ–ray energies, γ intensities, as well as for other nuclear properties are given. This evaluation replaces the A=152 evaluation published by Agda Artna–Cohen in Nuclear Data Sheets 79, 1 (1996) and the evaluation for 152Dy prepared by Balraj Singh and published in Nuclear Data Sheets 95, 995 (2002)

  14. Association of Shock, Coagulopathy, and Initial Vital Signs with Massive Transfusion in Combat Casualties

    DTIC Science & Technology

    2010-07-01

    Forces in the global war on terrorism: 2001–2004. Ann Surg. 2007;245:986–991. 3. Brohi K, Cohen MJ, Ganter MT, et al. Acute coagulopathy of trauma...Cohn SM, Murtha M. Early coagulopathy predicts mortality in trauma. J Trauma. 2003;55:39–44. 5. Hess JR, Brohi K, Dutton RP, et al. The coagulopathy of...Gilmore D, et al. Epidemiology of immediate and early trauma deaths at an urban Level I trauma center. Am Surg. 1998;64:950–954. 30. Brohi K, Singh J

  15. The Sacred and the Sword: A Study of how Religions View War

    DTIC Science & Technology

    1990-06-01

    army supplies , and weapons can be salvaged from the campaign, the state will be lucky. In addition, a countless number of men will desert or become...that supplies do not arrive in time. Such is the injury which warfare Inflicts upon men, the harm it brings to the world. And yet the rulers and...Odds Against V. P. Singh," Theb. Ecnomist, December 23, 1989, p. 37. 31. Drutakarma, qnjt 32. Zara Dian, "Religion and National Security i’n Southeast

  16. Catchment area-based evaluation of the AMC-dependent SCS-CN-based rainfall-runoff models

    NASA Astrophysics Data System (ADS)

    Mishra, S. K.; Jain, M. K.; Pandey, R. P.; Singh, V. P.

    2005-09-01

    Using a large set of rainfall-runoff data from 234 watersheds in the USA, a catchment area-based evaluation of the modified version of the Mishra and Singh (2002a) model was performed. The model is based on the Soil Conservation Service Curve Number (SCS-CN) methodology and incorporates the antecedent moisture in computation of direct surface runoff. Comparison with the existing SCS-CN method showed that the modified version performed better than did the existing one on the data of all seven area-based groups of watersheds ranging from 0.01 to 310.3 km2.

  17. A Key and Diagnostic Compendium to the Species of the Genus Pratylenchus Filipjev, 1936 (Lesion Nematodes)

    PubMed Central

    Handoo, Zafar Ahmad; Golden, A. Morgan

    1989-01-01

    An identification key to 63 species of Pratylenchus is given. A compendium of the most diagnostic characters to be used directly in identification of species is included as a practical alternative and supplement to the key. P. tenuis, P. similis, P. impar, P. ranjani, and P. neocapitatus are recognized as valid species on the basis of study of type specimens. P. hyderabadensis Singh &Gill, 1986 is synonymized with P. dasi Fortuner, 1985. P. hexincisus Taylor &Jenkins, 1957 is confirmed as occasionally having 4 -6 lines in lateral field (instead of 6 only). Comments on the status of some species and a list of species of the genus are given. PMID:19287599

  18. Enhancing Digital Skills Training: Interactive Multimedia Instruction

    DTIC Science & Technology

    2012-05-01

    Wittrock, 2000). For example, an AlU research effM examined modes of instruction (or a digital map int.erface using two groups of So ! diets : intimtry...Army Research Institute the BW:w.vioral and Social Seienc~s. (DTIC No. ADA $08002) Dyer, J. L., Singh, H., & Clark, T.L. (2005). Computllr-based...Scillllces. (DTIC No. ADA 474SS6) I Merrill, M. D. (2002). First principles ofinsrmctlon. Educalional1ecluw/ogy Resel.m;;lltmd Development, 50(3), 43-59

  19. Nuclear Data Sheets for A = 21

    NASA Astrophysics Data System (ADS)

    Firestone, R. B.

    2015-07-01

    This evaluation of A = 21 has been updated from previous evaluations published in 2004Fi10, 1998En04, 1990En08, and 1978En02. Coverage includes properties of adopted levels and γ-rays, decay-scheme data (energies, intensities and placement of radiations), and cross reference entries. The following tables continue the tradition of showing the systematic relationships between levels in A = 21. Much of the new data in this evaluations were taken directly from the xundl database, compiled under the direction of Balraj Singh, McMaster University. The evaluator is particularly appreciative of the efforts of the xundl compilers.

  20. Comment on ‘Yet another encounter with the golden ratio: balancing laminar bodies on the edge’

    NASA Astrophysics Data System (ADS)

    Dutta, Gautam; Mehta, Mitaxi

    2016-11-01

    When a circle is excised from a bigger circle so that the center of mass of the remaining portion is at a point in the inner edge, then the radii of the two circles are in the golden ratio. The same is true for any even sided regular polygon for excissions along certain symmetry axes of the figure as presented in Pathak and Singh (2016 Eur. J. Phys. 37 055001). We extend the result to shapes that do not have any rotational symmetry and also along axes which are not symmetry axes.

  1. Geometric measure of quantum discord with weak measurements

    NASA Astrophysics Data System (ADS)

    Li, Lei; Wang, Qing-Wen; Shen, Shu-Qian; Li, Ming

    2016-01-01

    Super quantum discord based on weak measurements was introduced by Singh and Pati (Ann Phys 343:141-152, 2014). We propose a geometric way of quantifying quantum discord with weak measurements. It is shown that this geometric measure of quantum discord with weak measurements (GQDW) is linearly dependent on geometric measure of quantum discord (Dakic et al. in Phys Rev Lett 105:190502, 2010) and only captures partial quantumness of the states. It is found that the quantum correlation can be extracted by a sequence of infinitesimal weak measurements. Finally, the level surfaces of GQDW for Bell-diagonal states are depicted and the results are demonstrated by explicit example.

  2. Dilepton production as a useful probe of quark gluon plasma with temperature dependent chemical potential quark mass

    NASA Astrophysics Data System (ADS)

    Kumar, Yogesh; Singh, S. Somorendro

    2016-07-01

    We extend the previous study of dilepton production using [S. Somorendro Singh and Y. Kumar, Can. J. Phys. 92 (2014) 31] based on a simple quasiparticle model of quark-gluon plasma (QGP). In this model, finite value of quark mass uses temperature dependent chemical potential the so-called Temperature Dependent Chemical Potential Quark Mass (TDCPQM). We calculate dilepton production in the relevant range of mass region. It is observed that the production rate is marginally enhanced from the earlier work. This is due to the effect of TDCPQM and its effect is highly significant in the production of dilepton.

  3. Restudy of surface tension of QGP with one-loop correction in the mean-field potential

    NASA Astrophysics Data System (ADS)

    Singh, S. Somorendro; Gupta, K. K.; Jha, A. K.

    2014-07-01

    Surface tension of quark-gluon plasma (QGP) evolution with one-loop correction in the mean-field potential is studied. First, with the correction, the stable QGP droplet size decreases. Then, the value of surface tension is found to be improved and it approaches to the lattice value of surface tension 0.24Tc3. Moreover, the ratio of the surface tension to the cube of the critical temperature is found to increase the value in comparison to earlier studies without correction factor [R. Ramanathan, K. K. Gupta, A. K. Jha and S. S. Singh, Pram. J. Phys. 68, 757 (2007)].

  4. Supergranular Convection

    NASA Astrophysics Data System (ADS)

    Udayashankar, Paniveni

    2015-12-01

    Observation of the Solar photosphere through high resolution instruments have long indicated that the surface of the Sun is not a tranquil, featureless surface but is beset with a granular appearance. These cellular velocity patterns are a visible manifestation of sub- photospheric convection currents which contribute substantially to the outward transport of energy from the deeper layers, thus maintaining the energy balance of the Sun as a whole.Convection is the chief mode of transport in the outer layers of all cool stars such as the Sun (Noyes,1982). Convection zone of thickness 30% of the Solar radius lies in the sub-photospheric layers of the Sun. Here the opacity is so large that heat flux transport is mainly by convection rather than by photon diffusion. Convection is revealed on four scales. On the scale of 1000 km, it is granulation and on the scale of 8-10 arcsec, it is Mesogranulation. The next hierarchial scale of convection , Supergranules are in the range of 30-40 arcsec. The largest reported manifestation of convection in the Sun are ‘Giant Cells’or ‘Giant Granules’, on a typical length scale of about 108 m.'Supergranules' is caused by the turbulence that extends deep into the convection zone. They have a typical lifetime of about 20hr with spicules marking their boundaries. Gas rises in the centre of the supergranules and then spreads out towards the boundary and descends.Broadly speaking supergranules are characterized by the three parameters namely the length L, the lifetime T and the horizontal flow velocity vh . The interrelationships amongst these parameters can shed light on the underlying convective processes and are in agreement with the Kolmogorov theory of turbulence as applied to large scale solar convection (Krishan et al .2002 ; Paniveni et. al. 2004, 2005, 2010).References:1) Noyes, R.W., The Sun, Our Star (Harvard University Press, 1982)2) Krishan, V., Paniveni U., Singh , J., Srikanth R., 2002, MNRAS, 334/1,2303) Paniveni

  5. Modified 8×8 quantization table and Huffman encoding steganography

    NASA Astrophysics Data System (ADS)

    Guo, Yongning; Sun, Shuliang

    2014-10-01

    A new secure steganography, which is based on Huffman encoding and modified quantized discrete cosine transform (DCT) coefficients, is provided in this paper. Firstly, the cover image is segmented into 8×8 blocks and modified DCT transformation is applied on each block. Huffman encoding is applied to code the secret image before embedding. DCT coefficients are quantized by modified quantization table. Inverse DCT(IDCT) is conducted on each block. All the blocks are combined together and the steg image is finally achieved. The experiment shows that the proposed method is better than DCT and Mahender Singh's in PSNR and Capacity.

  6. Supergranulation, a convective phenomenon

    NASA Astrophysics Data System (ADS)

    Udayashankar, Paniveni

    2015-08-01

    Observation of the Solar photosphere through high resolution instruments have long indicated that the surface of the Sun is not a tranquil, featureless surface but is beset with a granular appearance. These cellular velocity patterns are a visible manifestation of sub- photospheric convection currents which contribute substantially to the outward transport of energy from the deeper layers, thus maintaining the energy balance of the Sun as a whole.Convection is the chief mode of transport in the outer layers of all cool stars such as the Sun (Noyes,1982). Convection zone of thickness 30% of the Solar radius lies in the sub-photospheric layers of the Sun. Convection is revealed on four scales. On the scale of 1000 km, it is granulation and on the scale of 8-10 arcsec, it is Mesogranulation. The next hierarchial scale of convection ,Supergranules are in the range of 30-40 arcsec. The largest reported manifestation of convection in the Sun are ‘Giant Cells’or ‘Giant Granules’, on a typical length scale of about 108 m.'Supergranules' is caused by the turbulence that extends deep into the convection zone. They have a typical lifetime of about 20hr with spicules marking their boundaries. Gas rises in the centre of the supergranules and then spreads out towards the boundary and descends.Broadly speaking supergranules are characterized by the three parameters namely the length L, the lifetime T and the horizontal flow velocity vh . The interrelationships amongst these parameters can shed light on the underlying convective processes and are in agreement with the Kolmogorov theory of turbulence as applied to large scale solar convection (Krishan et al .2002 ; Paniveni et. al. 2004, 2005, 2010).References:1) Noyes, R.W., The Sun, Our Star (Harvard University Press, 1982)2) Krishan, V., Paniveni U., Singh , J., Srikanth R., 2002, MNRAS, 334/1,2303) Paniveni , U., Krishan, V., Singh, J., Srikanth, R., 2004, MNRAS, 347, 1279-12814) Paniveni , U., Krishan, V., Singh, J

  7. Consistent quantum prediction in spin-foam quantum cosmology

    NASA Astrophysics Data System (ADS)

    Craig, David

    2015-04-01

    A complete ``consistent histories'' framework is given for a covariant ``spin-foam'' quantum cosmological model, a highly symmetry-reduced (FLRW) model of covariant loop quantum gravity. A decoherence functional is constructed through which probabilities may be consistently extracted from quantum amplitudes. Branch wave functions corresponding to different possible quantum histories of the universe are described, such as whether the universe ``bounces'' at small volume or becomes singular. We discuss the construction and calculation of such branch wave functions, with an emphasis on the crucial role played by the decoherence of histories in arriving at self-consistent quantum predictions for these closed quantum systems. [Based on joint work with Parampreet Singh].

  8. Non-Adiabatic Holonomic Quantum Gates in an atomic system

    NASA Astrophysics Data System (ADS)

    Azimi Mousolou, Vahid; Canali, Carlo M.; Sjoqvist, Erik

    2012-02-01

    Quantum computation is essentially the implementation of a universal set of quantum gate operations on a set of qubits, which is reliable in the presence of noise. We propose a scheme to perform robust gates in an atomic four-level system using the idea of non-adiabatic holonomic quantum computation proposed in [1]. The gates are realized by applying sequences of short laser pulses that drive transitions between the four energy levels in such a way that the dynamical phases vanish. [4pt] [1] E. Sjoqvist, D.M. Tong, B. Hessmo, M. Johansson, K. Singh, arXiv:1107.5127v2 [quant-ph

  9. Theory of Lattice Strain for Materials Undergoing Plastic Deformation

    NASA Astrophysics Data System (ADS)

    Karato, S.

    2008-12-01

    Radial x-ray diffraction is used to probe physical properties of materials including elastic and plastic properties. The theory used behind such an practice is the one developed by Singh (1993) in which the relation between lattice strain and elastic constants and macroscopic stress is derived. In this theory, the variation of inferred stress with the crystallographic planes, (hkl), is due to the elastic anisotropy. However, recent experimental studies showed that in many cases, the variation of stress with (hkl) far exceeds the value expected from this theory. I have developed a modified theory to rectify this problem with Singh's theory. In Singh's theory, the stress distribution in a polycrystalline material is treated only either unrelaxed or relaxed state. The role of plastic deformation is included only to the extent that plastic flow influences this stress state. Such an assumption corresponds to a Voigt model behavior, which is not an appropriate model at high temperatures where continuing plastic flow occurs with concurrent microscopic equilibrium, elastic deformation. This is a Maxwell model type behavior, and my model provides a stress analysis in a Maxwell material with anisotropic and non-linear power-law rheology. In this theory, the lattice strain corresponding to an imposed macroscopic strain-rate is calculated by three steps: (i) conversion of macroscopic strain-rate to macroscopic stress, (ii) conversion of macroscopic stress to microscopic stress at individual grains, and (iii) calculation of microscopic strain due to microscopic stress. The first step involves anisotropy in macroscopic viscosity that depends on anisotropy in crystal plasticity and lattice-preferred orientation. The second step involves anisotropic crystal plasticity and finally the third step involves elastic crystal anisotropy. In most cases, the influence of LPO is weak and in such a case, the lattice strain depends on (hkl) due to the anisotropy in both elastic and plastic

  10. EPR, UV-vis, magnetic, spectral studies and electrochemical behaviour of mononuclear transition metal complexes derived from novel hexa-aza-macrotricyclic ligand

    NASA Astrophysics Data System (ADS)

    Chandra, Sulekh; Gupta, Nidhi; Gupta, Rachna; Bawa, Sukhwant Singh

    2005-11-01

    Aza-macrocyclic complexes have gained importance because of their pharmacological properties [N.K. Singh, Srivastava, Trans. Met. Chem. 25 (2000) 133]. Hexa-aza-macrocyles containing glutarimide efficiently coordinate as hexa-dentate ligand, to give complexes of Cu(II) possessing tetragonal structure and Mn(II), Co(II) and Ni(II) metal ions that are essentially octahedral. Spectroscopic, and chemical characterizations of these systems are presented in this article. For Ni(II) complexes results on electron transfer processes measured by cyclic voltammetry and colourimetry have been studied.

  11. Darwin and Mendel today: a comment on "Limits of imagination: the 150th Anniversary of Mendel's Laws, and why Mendel failed to see the importance of his discovery for Darwin's theory of evolution".

    PubMed

    Liu, Yongsheng; Li, Xiuju

    2016-01-01

    We comment on a recent paper by Rama Singh, who concludes that Mendel deserved to be called the father of genetics, and Darwin would not have understood the significance of Mendel's paper had he read it. We argue that Darwin should have been regarded as the father of genetics not only because he was the first to formulate a unifying theory of heredity, variation, and development -- Pangenesis, but also because he clearly described almost all genetical phenomena of fundamental importance, including what he called "prepotency" and what we now call "dominance" or "Mendelian inheritance". The word "gene" evolved from Darwin's imagined "gemmules", instead of Mendel's so-called "factors".

  12. The Indian Ocean - An Area of Future Conflict

    DTIC Science & Technology

    1981-06-05

    abstract entered In Block 20, I difmt from Report) Approved for public release; distribution unlimited. IS. SUPPLEMENTARY NOTES Master of Military Art ...College In partial Sful f01 mint o: t".e requirements for’m the MASTER OF MtLITARY ART AND SCIENCE by ’RAVI INDEk SINGH KAHLON, LTC, INDIA Graduate...oc’m-n "must be referred to: HQ TRADOC, Attn: ATCS-D, Fort Monroe, VA 23651. A- A Master of Military Art and Science thesis presented to the faculty of

  13. JPRS Report, Near East and South Asia.

    DTIC Science & Technology

    1989-01-12

    increase of dairy product in the Kingdom, a country with many disadvan- tages including hot temperatures and lack of grasslands. Among these reasons are...secretary of the Congress(I), in a statement said: "The basic inconsistency of Mr V.P. Singh’s character may prove very costly for our political...when it was shot down by the U.S. Navy on July 3. Flight 655 was en route to Dubai from Bandar Abbas. On Iran Air’s performance, Majidi said despite

  14. Synthesis and Characterization of a Hyperbranched Hydrogen Bond Acidic Carbosilane Sorbent Polymer

    DTIC Science & Technology

    2010-01-01

    double bond of HCSA2 (1) electrophilically attacks the ketone carbon of the HFA. The bonds are formed via a pericyclic mechanism which requires formation...val- ues for H, 3.1% and C, 35.4% compared with the theoretical weight percents of H, 2.2%, and C, 34.3%. Fluorine composi- tion numbers were...Srcic, S. Acta Chim Solv 2004, 51, 373–394. 43 Bhadury, P. S.; Dubey, V.; Singh, S.; Saxena, C. J. Fluorine Chem 2005, 126, 1252–1256. 44 Grate, J. W

  15. Compilation of NRL Publications on High Temperature Superconductivity.

    DTIC Science & Technology

    1987-01-01

    Gubser, and S.A, Wolf (to be published in Proceedings of Novel Mechanisms Conf.) , Suprconducting Phase Transitions in the La-M-Cu-O Layered...Wolf, C.S. Pande, A.K. Singh, E.F. Skelton and B.A. Bender (to be published in Novel Mechanisms Conf. Evidence of conventional superconductivity in I...165 V.Z. Kresin and S.A. Wolf (to be published in Novel Mechanisms Conf.) iv Complex Hamiltonians: Common Features of Mechanisms for High

  16. Report of Symposium: Applications of Advanced and Innovative Computational Methods to Defense Science and Engineering.

    DTIC Science & Technology

    1994-11-01

    Dairy delivery to military deployment) • University Classes • Airline Scheduling of crew, planes in static or dynamic (Midwest snowstorm) cases...VVHY IS 4A; £xP£/it MENTAL ASTKOP*YS\\Z\\ST Gf\\j/AJ6 A TAChr Ar A COW >UT,AJG (AAJJWS*: BecAose /T’S A^OST HALLOW ecu?) W/Ho COULD...LETTERS TO NATURE Theoretical determination that electrons act as anions in the electride Cs+(15-crown-5)2-e~ David J. Singh*, Henry Krakauer

  17. Comparison of the Side Populations in Pretreatment and Postrelapse Neuroblastoma Cell Lines

    DTIC Science & Technology

    2010-08-01

    discussion 1890. [6] Kern SE and Shibata D (2007). The fuzzy math of solid tumor stem cells: a per- spective. Cancer Res 67, 8985–8988. Figure 5...Squire J, and Dirks PB (2003). Identification of a cancer stem cell in human brain tumors . Cancer Res 63, 5821–5828. [14] Singh SK, Hawkins C, Clarke...Sciences, Bethesda, MD, USA Abstract Cancer stem–like cells have been identified in both primary tumors and in cell lines and seem to have a high degree

  18. Three new species of Baeoentedon Girault (Hymenoptera: Eulophidae) from China, with the first record of whitefly host association (Hemiptera: Aleyrodidae).

    PubMed

    Wang, Zhu-Hong; Huang, Jian; Polaszek, Andrew

    2014-07-01

    Three new species of Baeoentedon Girault (Hymenoptera: Eulophidae) are described from China, Baeoentedon balios Wang, Huang & Polaszek sp. nov., Baeoentedon bouceki Wang, Huang & Polaszek sp. nov. and Baeoentedon virgatus Wang, Huang & Polaszek sp. nov. Both female and male of Baeoentedon balios were reared from the whitefly Pealius spina (Singh) (Hemiptera: Aleyrodidae) on the bodhi tree Ficus religiosa L. (Urticales: Moraceae). The male and the whitefly host association of Baeoentedon are recorded for the first time. A key is also provided to females of the world species of the genus.

  19. A possible mechanism for the observed streaming of O(+) and H(+) ions at nearly equal speeds in the distant magnetotail

    NASA Technical Reports Server (NTRS)

    Singh, N.; Schunk, R. W.

    1985-01-01

    In recent years, O(+) and H(+) ions streaming away from the earth along geomagnetic field lines have been observed in the distant magnetotail region. In the present paper, it is suggested that the transverse acceleration of the ions occurs on auroral field lines at altitudes above the field-aligned potential drops, where ion beams and electrostatic hydrogen cyclotron (EHC) waves have been simultaneously observed. It is pointed out that the preferential acceleration of O(+) relative to H(+) occurs through the interaction of O(+) ions with weak EHC waves, as suggested by Singh et al. (1983). A quantitative explanation is provided for the observed relationship between the energies of O(+) and H(+) ions.

  20. Techniques for Exploiting Unlabeled Data

    DTIC Science & Technology

    2008-10-01

    Moore, Ar- jit Singh, Jure Leskovec, Stano Funiak, Andreas Krause, Gaurav Veda, John Lang - ford, R. Ravi, Peter Lee, Srinath Sridhar, Virginia Vassilevska...based on ²-cover size, e.g., Benedek et al.[7]. The idea here is that suppose we have a known distribution D and we identify some hypothesis h that has...examples. Journal of Machine Learning Research, 7:2399–2434, 2006. 2.1.2, 5.1.2 [7] G.M. Benedek and A. Itai. Learnability with respect to a fixed

  1. India-U.S. Relations

    DTIC Science & Technology

    2007-06-26

    Commission Deputy Minister Montek Singh Ahluwalia, and Power Minister Sushil Shinde . Among formal bilateral sessions over the past year were the following...versions of the legislation and provided a 30-page explanatory statement (H.Rept. 109-721). On December 18, President Bush signed the Henry J . Hyde...in Rajya Sabha on Civil Nuclear Energy Coopera t i o n w i t h t h e U n i t e d S t a t e s , ” A u gu s t 17 , 2006 , a t [http

  2. Development of Highly Ordered Heterostructured Semiconductor Nanowire Arrays for Sub-Wavelength Optical Devices

    DTIC Science & Technology

    2007-06-01

    Page 1 of 30 LIST OF PUBLICATIONS 1. T. Xu, S. Yang, S. V. Nair and H. E. Ruda, "Confined modes in finite-size photonic crystals ", Phys. Rev. B 2...045126 (2005). 2. S. Yang, T. Xu, H. E. Ruda and M. Cowan, "Numerical study of anomalous refraction in photonic crystals ", Phys. Rev. B 72, 075128 (2005...Ruda, "Properties and applications of photonic crystals " in "Optical properties of condensed matter and applications", Ed. J. Singh, J. Wiley & Sons

  3. Near East/South Asia Report

    DTIC Science & Technology

    2007-11-02

    and propaganda films for the U.S. police and others. Second, the great demand for films shown by children and teenagers who find their object in...who, a^few years ago, bullied the U.S. State Department into granting a visitor’s visa to Jagjit Singh Chauhan, the London-based "president of the...old world champion hockey team. Is that not national suicide ? And if I were Rajiv Gandhi, one of the first steps I would take would be to remove

  4. Detection of Energetic Materials by Laser Photofragmentation/Fragment Detection and Pyrolysis/Laser-Induced Fluorescence

    DTIC Science & Technology

    2001-02-01

    Analysis." Applied Spectroscopy Reviews, vol. 31, pp. 1-72, 1996. 4. Huang, S. D., L. Kolaitis, and D. M. Lubman. "Detection Of Explosives Using Laser...Desorption/Mass Spectrometry." Applied Spectroscopy , vol. 41, pp. 137 1-1376, 1987. 5. Riris, H., C. B. Carisle, D. F. McMillen, and D. E. Cooper...Photofragmentation/Ionization Spectrometry." Applied Spectroscopy , vol. 47, no. 11, pp. 1907-1912, 1993. 10. Wu, D., J. Singh, F. Yueh, and D. Monts. Ŗ,4,6

  5. Bianchi type-I universe in Lyra manifold with quadratic equation of state

    NASA Astrophysics Data System (ADS)

    Şen, R.; Aygün, S.

    2017-02-01

    In this study, we have solved Einstein field equations for Bianchi type I universe model in Lyra manifold with quadratic equation of state (EoS) p = ap(t)2 - ρ(t). Where α ≠0 is an important constant. Cosmic pressure, density and displacement vector (β2) are related with α constant. In this study β2 is a decreasing function of time and behaves like a cosmological constant. These solutions agree with the studies of Halford, Pradhan and Singh, Aygün et al., Agarwal et al., Yadav and Haque as well as SN Ia observations.

  6. Radiation Protection by the Antioxidant Alpha-Tocopherol Succinate

    DTIC Science & Technology

    2005-01-01

    family of 8 tocols—4 each of α, β, γ, and δ tocopherols and tocotrienols (Figure 1). O CH3 R1 R2 HO CH3 CH3 CH3 CH3 CH3 R1 = R2 = CH3 d- alpha ...CH3 CH3 R1 = R2 = CH3 R1 = R2 = H R1 = H, R2 = CH3 R1 = CH3, R2 = H d- alpha - tocotrienol d-beta- tocotrienol d-gamma- tocotrienol d-delta- tocotrienol ...Radiation Protection by the Antioxidant Alpha -Tocopherol Succinate Vijay K. Singh1, V. Srinivasan1, Raymond Toles1, Patience Karikari1, Thomas

  7. Seroprevalence of bovine herpesvirus-1 antibodies in bovines in five districts of Uttarakhand

    PubMed Central

    Thakur, Vipul; Kumar, Mahesh; Rathish, R. L.

    2017-01-01

    Aim: This study was conducted to know the status of bovine herpesvirus-1 (BHV-1) antibodies in the bovines of the selected area of Uttarakhand. Materials and Methods: A total of 489 serum samples, 392 of cattle and 97 of buffaloes were randomly collected from the unvaccinated bovine population of five districts viz., Dehradun, Haridwar, Nainital, Pithoragarh, and Udham Singh Nagar and were tested by avidin biotin enzyme-linked immunosorbent assay for BHV-1 antibodies. Results: The overall prevalence was observed to be 29.03%. At district level, the highest prevalence was recorded in Pithoragarh district (40.00%) while it was lowest in district Udham Singh Nagar (16.00%). The prevalence of BHV-1 antibodies was found to be higher in unorganized dairy units (31.02%) compared to organized farms (26.51%) in Uttarakhand. Buffaloes were found to have greater prevalence (38.14%) than cattle (26.78%) while on sex-wise basis; it was found that more females (30.08%) were harboring antibodies to the virus than males (16.21%). Conclusion: The study revealed that the population in the area under study has been exposed to BHV-1 and hence prevention and control strategies must be implemented. PMID:28344394

  8. Wheeler-DeWitt quantization and singularities

    NASA Astrophysics Data System (ADS)

    Falciano, F. T.; Pinto-Neto, N.; Struyve, W.

    2015-02-01

    We consider a Bohmian approach to the Wheeler-DeWitt quantization of the Friedmann-Lemaître-Robertson-Walker model and investigate the question of whether or not there are singularities, in the sense that the Universe reaches zero volume. We find that for generic wave functions (i.e., nonclassical wave functions), there is a nonzero probability for a trajectory to be nonsingular. This should be contrasted to the consistent histories approach for which it was recently shown by Craig and Singh that there is always a singularity. This result illustrates that the question of singularities depends much on which version of quantum theory one adopts. This was already pointed out by Pinto-Neto et al., albeit with a different Bohmian approach. Our current Bohmian approach agrees with the consistent histories approach by Craig and Singh for single-time histories, unlike the one studied earlier by Pinto-Neto et al. Although the trajectories are usually different in the two Bohmian approaches, their qualitative behavior is the same for generic wave functions.

  9. Simulation of nose whistlers: An application to low latitude whistlers

    NASA Astrophysics Data System (ADS)

    Singh, Kalpana; Singh, R. P.; Kumar Singh, Abhay; Singh, R. N.

    2006-05-01

    Simulation technique for whistler mode signal propagating through inhomogeneous plasma using WKB approximation has been developed (Singh, K., Singh, R.P., Ferencz, O.E., 2004. Simulation of whistler mode propagation for low latitude stations. Earth Planet Space 56, 979-987). In the present paper, we have used it for the analysis of recorded signals at low latitudes and estimated the nose frequency, which is not observed on the dynamic spectra. At low latitudes nose frequency is ˜100 kHz or more and therefore it is absent in the dynamic spectra due to attenuation of the signal at higher frequencies. The importance of nose frequency is in determining the exact path of propagation, which is required in probing of ambient medium. It is shown that the method permits to study the nose frequency variation, it can be used to deduce physical parameters as the global electric field. A case study permits to get a reasonable value of the electric field, which up to now could not be done at very low latitude.

  10. Mitochondria in biology and medicine--2012.

    PubMed

    Desler, Claus; Rasmussen, Lene Juel

    2014-05-01

    As the understanding of mitochondria and their importance for the cell and organism is developing, increasing evidence is demonstrating the organelle to be intricately involved in an extensive range of pathologies. This range of pathologies include general signs of premature aging, neuro-muscular dysfunctions, cancer, diabetes, various heart diseases, inflammation and other conditions not previously known to be related to mitochondrial function. A better understanding of mitochondria therefore allows a better understanding of related pathologies. It enables the usage of mitochondrial function as biomarkers for the diseases and most important, it opens the possibility of a treatment or a cure for a disease. "Mitochondria in Biology and Medicine" was the title of the second annual conference of Society of Mitochondrial Research and Medicine-India. The conference was organized by Rana P. Singh, Keshav Singh and Kumarasamy Thangaraj, and was held at the newly opened School of Life Sciences, Central University of Gujarat (CUG), Gandhinagar, India, during 2-3 November 2012. The conference featured talks from internationally renowned scientists within the field of mitochondrial research and offered both students and fellow researchers a comprehensive update to the newest research within the field. This paper summarizes key outcomes of the presentations.

  11. Characterization of a 21-Story Reinforced Building in the Valley of Mexico Using MEMS Accelerometers.

    NASA Astrophysics Data System (ADS)

    Husker, A. L.; Dominguez, L. A.; Becerril, A.; Espejo, L.; Cochran, E. S.

    2014-12-01

    Low cost MEMS accelerometers are becoming increasingly higher resolution making them useful in strong motion studies. Here we present a building response analysis in the lakebed zone of the Valley of Mexico. The Valley of Mexico represents one of the highest seismic risk locations in the world and incorporates Mexico City and part of Mexico State. More than 20 million people live there and it is the political and economic center of Mexico. In addition the valley has very high site effects with amplifications 100 - 500 times that of sites outside of the basin (Singh et al., 1988; Singh et al., 1995). We instrumented a 21-story building with MEMS accelerometers as part of the Quake Catcher Network or Red Atrapa Sismos as it is called in Mexico. The building known as the Centro Cultural de Tlateloco is located in an important historical and political area as well as a zone with some of the highest amplifications in the Valley of Mexico that had some of the worst destruction after the 1985 M8.1 Michoacan earthquake. During the earthquake most of the buildings that failed were between 7 - 18 stories tall. The peak accelerations near Tlateloco were at periods of 2 seconds. Since the earthquake the building has been retrofitted with N-S crossing supports to help withstand another earthquake. We present the measurements of frequencies and amplifications between floors for the length of the building.

  12. Immunotherapy of Uveal Melanoma: Vaccination Against Cancer.

    PubMed

    Kummer, Mirko; Schuler-Thurner, Beatrice

    2017-01-01

    Uveal melanoma is the most frequently occurring primary intraocular tumor in adults, with an incidence of about 5 out of 100,000 per year, the incidence rising with increasing age (Lipski, Klin Monbl Augenheilkd 230:1005-1019, 2013; Metz et al., Klin Monbl Augenheilkd 230:686-691, 2013; Singh and Topham, Ophthalmology 110:956-961, 2003). Often diagnosed late due to a lack of early symptoms, this kind of melanoma is associated with a poor prognosis. Approximately 50 % of the patients develop distant metastases (Lipski, Klin Monbl Augenheilkd 230:1005-1019, 2013; Metz et al., Klin Monbl Augenheilkd 230:686-691, 2013; Singh and Topham, Ophthalmology 110:956-961, 2003). In sharp contrast to cutaneous melanoma, uveal melanoma shows a strong liver tropism and spreads exclusively via the hematogenous route (except for tumors with extraocular expansion) (Heindl et al., Arch Ophthalmol 128:1001-1008, 2010). The most likely reason for this observation is the lack of lymphatic vessels in the choroid and alymphatic barrier of the sclera (Schlereth et al., Exp Eye Res 125:203-209, 2014; Schroedl et al., Invest Ophthalmol Vis Sci 49:5222-5229, 2008). Due to its location in the immune-privileged eye, the uveal melanoma is widely protected from the immune system. Therefore, the goal of the approach presented here, of a "personalized vaccination therapy" is to help the immune system recognize and fight the tumor.

  13. Additions to the Encyrtidae and Mymaridae (Chalcidoidea) of India with new distribution and host records for some species

    PubMed Central

    Rameshkumar, A.; V, Naveen

    2015-01-01

    Abstract Background Encyrtidae and Mymaridae of India have not been surveyed in depth and hosts are not known for most of the species as the methods of collections used are passive and do not yield firsthand information on the hosts. Based on our ongoing surveys on the Encyrtidae and Mymaridae of India, we report here new distribution and host records for some species. New information Acmopolynema campylurum Xu and Lin, Litus cynipseus Haliday, Omyomymar glabrum Lin and Chiappini and Platystethynium Ogloblin (Mymaridae), and Rhytidothorax purpureiscutellum (Girault) (Encyrtidae) are reported for the first time from India. Anagyrus aquilonaris (Noyes and Hayat) is recorded as new to Arunachal Pradesh and Meghalaya. Paraphaenodiscus indicus Singh and Agarwal and Paraphaenodiscus monawari Bhuiya are recorded from south India for the first time, the latter on a new host, Pulvinaria polygonata. Chorizococcus sorghi Williams (Pseudococcidae) is reported as a host for Cryptanusia ajmerensis (Fatma & Shafee), for which no hosts are hitherto known and the male of Cryptanusia is documented for the first time. Aclerda sp. is recorded as a new host for Neastymachus axillaris Singh, Agarwal and Basha. PMID:26069438

  14. Revision of Metahaliotrema Yamaguti, 1953 (Monogenoidea: Dactylogyridae), with new and previously described species from the spotted scat Scatophagus argus (Linnaeus) (Perciformes: Scatophagidae) in Vietnam.

    PubMed

    Kritsky, Delane C; Nguyen, Ha Van; Ha, Ngo Duy; Heckmann, Richard A

    2016-05-01

    An emended diagnosis of Metahaliotrema Yamaguti, 1953 (Monogenoidea: Dactylogyridae) is provided based on specimens of six species collected from the spotted scat Scatophagus argus (Linnaeus) (Scatophagidae) in Vietnam: M. scatophagi Yamaguti, 1953 (type-species); M. cf. yamagutii Mizelle & Price, 1964; M. mizellei Venkatanarasaiah, 1981; M. kulkarnii Venkatanarasaiah, 1981; M. ypsilocleithrum n. sp.; and M. similis n. sp. Methaliotrema filamentosum Venkatanarasaiah, 1981 from the whipfin silver-biddy Gerres filamentosus Cuvier (Gerreidae) is included as the only other valid member of the genus. Metahaliotrema arii Yamaguti, 1953 from an ariid catfish is considered incertae sedis within the Dactylogyridae; and Metahaliotrema srivastavai Singh & Agarwal, 1994 from a bagrid catfish is transferred to Chauhanellus Bychowsky & Nagibina, 1969 as Chauhanellus srivastavai (Singh & Agarwal, 1994) n. comb. Metahaliotrema geminatohamula Pan, Ding & Zhang, 1995 from spotted scat in China is determined to be a junior subjective synonym of M. scatophagi. The two new species and M. scatophagi, M. mizellei, and M. kulkarnii are described or redescribed based on specimens from Vietnam.

  15. Drying characteristics of paddy in an integrated dryer.

    PubMed

    Manikantan, M R; Barnwal, P; Goyal, R K

    2014-04-01

    Drying characteristics of paddy (long grain variety PR-118 procured from PAU, Ludhiana) in an integrated dryer using single as well as combined heating source was studied at different air temperatures. The integrated dryer comprises three different air heating sources such as solar, biomass and electrical. Drying of paddy occurred in falling rate period. It was observed that duration of drying of paddy from 22 to 13 % moisture content (w.b.) was 5-9 h depending upon the source of energy used. In order to select a suitable drying curve, six thin layer-drying models (Newton, Page, Modified Page, Henderson and Pabis, Logarithmic and Wang and Singh) were fitted to the experimental moisture ratio data. Among the mathematical models investigated, Wang and Singh model best described the drying behaviour of paddy using solar, biomass and combined heating sources with highest coefficient of determination (r (2)) values and least chi-square, χ (2), mean bias error (MBE) and root mean square error (RMSE) values. However, Page model adequately described the drying behavior of paddy using electrical heating source.

  16. Effect of ultrasound pre-treatment on the drying kinetics of brown seaweed Ascophyllum nodosum.

    PubMed

    Kadam, Shekhar U; Tiwari, Brijesh K; O'Donnell, Colm P

    2015-03-01

    The effect of ultrasound pre-treatment on the drying kinetics of brown seaweed Ascophyllum nodosum under hot-air convective drying was investigated. Pretreatments were carried out at ultrasound intensity levels ranging from 7.00 to 75.78 Wcm(-2) for 10 min using an ultrasonic probe system. It was observed that ultrasound pre-treatments reduced the drying time required. The shortest drying times were obtained from samples pre-treated at 75.78 Wcm(-2). The fit quality of 6 thin-layer drying models was also evaluated using the determination of coefficient (R(2)), root means square error (RMSE), AIC (Akaike information criterion) and BIC (Bayesian information criterion). Drying kinetics were modelled using the Newton, Henderson and Pabis, Page, Wang and Singh, Midilli et al. and Weibull models. The Newton, Wang and Singh, and Midilli et al. models showed the best fit to the experimental drying data. Color of ultrasound pretreated dried seaweed samples were lighter compared to control samples. It was concluded that ultrasound pretreatment can be effectively used to reduce the energy cost and drying time for drying of A. nodosum.

  17. Determining the Probability Distribution of Hillslope Peak Discharge Using an Analytical Solution of Kinematic Wave Time of Concentration

    NASA Astrophysics Data System (ADS)

    Baiamonte, Giorgio; Singh, Vijay P.

    2016-04-01

    Hillslope hydrology is fundamental for understanding the flood phenomenon and for evaluating the time of concentration. The latter is a key variable for predicting peak discharge at the basin outlet and for designing urban infrastructure facilities. There have been a multitude of studies on the hydrologic response at the hillslope scale, and the time of concentration has been derived for different approaches. One approach for deriving hillslope response utilizes, in a distributed form, the differential equations of unsteady overland flow, specifically developed at the hydrodynamic scale, in order to account for the spatial heterogeneity of soil characteristics, topography, roughness and vegetation cover on the hillslope. Therefore, this approach seemingly mimics the complete hydraulics of flow. However, the very complex patterns generated by spatial heterogeneity can cause considerable error in the prediction even by very sophisticated models. Another approach that directly operates at the hillslope scale is by averaging over the hillslope the soil hydraulics, the topography, and the roughness characteristics. A physically-based lumped model of hillslope response was first proposed by Horton (1938), under the assumption that the flow regime is intermediate between laminar and turbulent regimes (transitional flow regime), by applying the mass conservation equation to the hillslope as a whole and by using the kinematic wave assumption for the friction slope (Singh, 1976, 1996). Robinson et al. (1995) and Robinson and Sivapalan (1996) generalized Horton's approach, suggesting an approximate solution of the overland flow equation that is valid for all flow regimes. Agnese et al. (2001) derived an analytical solution of a nonlinear storage model of hillslope response that is valid for all flow regimes, and the associated time of concentration. Recently, the well-known kinematic wave equation for computing the time of concentration for impervious surfaces has been

  18. Statistical Analysis of Tank 5 Floor Sample Results

    SciTech Connect

    Shine, E. P.

    2013-01-31

    Sampling has been completed for the characterization of the residual material on the floor of Tank 5 in the F-Area Tank Farm at the Savannah River Site (SRS), near Aiken, SC. The sampling was performed by Savannah River Remediation (SRR) LLC using a stratified random sampling plan with volume-proportional compositing. The plan consisted of partitioning the residual material on the floor of Tank 5 into three non-overlapping strata: two strata enclosed accumulations, and a third stratum consisted of a thin layer of material outside the regions of the two accumulations. Each of three composite samples was constructed from five primary sample locations of residual material on the floor of Tank 5. Three of the primary samples were obtained from the stratum containing the thin layer of material, and one primary sample was obtained from each of the two strata containing an accumulation. This report documents the statistical analyses of the analytical results for the composite samples. The objective of the analysis is to determine the mean concentrations and upper 95% confidence (UCL95) bounds for the mean concentrations for a set of analytes in the tank residuals. The statistical procedures employed in the analyses were consistent with the Environmental Protection Agency (EPA) technical guidance by Singh and others [2010]. Savannah River National Laboratory (SRNL) measured the sample bulk density, nonvolatile beta, gross alpha, and the radionuclide1, elemental, and chemical concentrations three times for each of the composite samples. The analyte concentration data were partitioned into three separate groups for further analysis: analytes with every measurement above their minimum detectable concentrations (MDCs), analytes with no measurements above their MDCs, and analytes with a mixture of some measurement results above and below their MDCs. The means, standard deviations, and UCL95s were computed for the analytes in the two groups that had at least some measurements

  19. Study of Surface Enhanced Raman Scattering of Alizarin and Crystal Violet Dyes

    NASA Astrophysics Data System (ADS)

    Gopal, Ram; Swarnkar, Raj Kumar

    2010-06-01

    Surface enhanced Raman scattering (SERS) plays a vital role in analytical chemistry to characterize ultra trace quantity of organic compounds and biological samples. Two mechanisms have been considered to explain the SERS effect. The main contribution arises from a huge enhancement of the local electromagnetic field close to surface roughness of the metal structures, due to the excitation of a localized surface plasmon, while a further enhancement can be observed for molecules adsorbed onto specific sites when resonant charge transfer occurs. SERS signals have been observed from adsorbates on many metallic surfaces like Ag, Au, Ni, Cu etc. Additionally, metal oxide nanoparticles also show SERS signals It has now been established that SERS of analyte material is highly dependent on the type of substrate involved. Many types of nanostructures like nanofilms, nanorods, nanospheres etc. show highly efficient SERS signals. In particular, there are two routes available for the synthesis of these nanomaterials: the chemical route and the physical route. Chemical route involves many types of reducing agents and capping agents which can interfere in origin and measurement of these signals. The physical route avoids these anomalies and therefore it is suitable for the study of SERS phenomenon. Pulsed laser ablation in liquid medium is an excellent top down technique to produce colloidal solution of nanoparticles with desired shape and size having surface free from chemical contamination, which is essential requirement for surface application of nanoparticles. The present work deals with the study of SERS of Crystal violet dye and Alizarin group dye on Cu@ Cu_2O and Ag colloidal nanoparticles synthesized by pulsed laser ablation. M. Fleishchmann, P. J. Hendra, and A. J. McQuillian Chem. Phys. Lett., 26, 163, 1974. U. Wenning, B. Pettinger, and H. Wetzel Chem. Phys. Lett., 70, 49, 1980. S. C. Singh, R. K. Swarnkar, P. Ankit, M. C. Chattopadhyaya, and R. Gopal AIP Conf. Proc

  20. STATISTICAL ANALYSIS OF TANK 5 FLOOR SAMPLE RESULTS

    SciTech Connect

    Shine, E.

    2012-03-14

    Sampling has been completed for the characterization of the residual material on the floor of Tank 5 in the F-Area Tank Farm at the Savannah River Site (SRS), near Aiken, SC. The sampling was performed by Savannah River Remediation (SRR) LLC using a stratified random sampling plan with volume-proportional compositing. The plan consisted of partitioning the residual material on the floor of Tank 5 into three non-overlapping strata: two strata enclosed accumulations, and a third stratum consisted of a thin layer of material outside the regions of the two accumulations. Each of three composite samples was constructed from five primary sample locations of residual material on the floor of Tank 5. Three of the primary samples were obtained from the stratum containing the thin layer of material, and one primary sample was obtained from each of the two strata containing an accumulation. This report documents the statistical analyses of the analytical results for the composite samples. The objective of the analysis is to determine the mean concentrations and upper 95% confidence (UCL95) bounds for the mean concentrations for a set of analytes in the tank residuals. The statistical procedures employed in the analyses were consistent with the Environmental Protection Agency (EPA) technical guidance by Singh and others [2010]. Savannah River National Laboratory (SRNL) measured the sample bulk density, nonvolatile beta, gross alpha, radionuclide, inorganic, and anion concentrations three times for each of the composite samples. The analyte concentration data were partitioned into three separate groups for further analysis: analytes with every measurement above their minimum detectable concentrations (MDCs), analytes with no measurements above their MDCs, and analytes with a mixture of some measurement results above and below their MDCs. The means, standard deviations, and UCL95s were computed for the analytes in the two groups that had at least some measurements above their

  1. Statistical Analysis Of Tank 5 Floor Sample Results

    SciTech Connect

    Shine, E. P.

    2012-08-01

    Sampling has been completed for the characterization of the residual material on the floor of Tank 5 in the F-Area Tank Farm at the Savannah River Site (SRS), near Aiken, SC. The sampling was performed by Savannah River Remediation (SRR) LLC using a stratified random sampling plan with volume-proportional compositing. The plan consisted of partitioning the residual material on the floor of Tank 5 into three non-overlapping strata: two strata enclosed accumulations, and a third stratum consisted of a thin layer of material outside the regions of the two accumulations. Each of three composite samples was constructed from five primary sample locations of residual material on the floor of Tank 5. Three of the primary samples were obtained from the stratum containing the thin layer of material, and one primary sample was obtained from each of the two strata containing an accumulation. This report documents the statistical analyses of the analytical results for the composite samples. The objective of the analysis is to determine the mean concentrations and upper 95% confidence (UCL95) bounds for the mean concentrations for a set of analytes in the tank residuals. The statistical procedures employed in the analyses were consistent with the Environmental Protection Agency (EPA) technical guidance by Singh and others [2010]. Savannah River National Laboratory (SRNL) measured the sample bulk density, nonvolatile beta, gross alpha, and the radionuclide, elemental, and chemical concentrations three times for each of the composite samples. The analyte concentration data were partitioned into three separate groups for further analysis: analytes with every measurement above their minimum detectable concentrations (MDCs), analytes with no measurements above their MDCs, and analytes with a mixture of some measurement results above and below their MDCs. The means, standard deviations, and UCL95s were computed for the analytes in the two groups that had at least some measurements

  2. Sandia Simple Particle Tracking (Sandia SPT) v. 1.0

    SciTech Connect

    Anthony, Stephen M.

    2015-06-15

    Sandia SPT is designed as software to accompany a book chapter being published a methods chapter which provides an introduction on how to label and track individual proteins. The Sandia Simple Particle Tracking code uses techniques common to the image processing community, where its value is that it facilitates implementing the methods described in the book chapter by providing the necessary open-source code. The code performs single particle spot detection (or segmentation and localization) followed by tracking (or connecting the detected particles into trajectories). The book chapter, which along with the headers in each file, constitutes the documentation for the code is: Anthony, S.M.; Carroll-Portillo, A.; Timlon, J.A., Dynamics and Interactions of Individual Proteins in the Membrane of Living Cells. In Anup K. Singh (Ed.) Single Cell Protein Analysis Methods in Molecular Biology. Springer

  3. Preface

    NASA Astrophysics Data System (ADS)

    Eliasson, B.; Stenflo, L.; Bingham, R.; Mendonça, J. T.; Mendonça

    2013-12-01

    This special issue is devoted to the memory of Professor Padma Kant Shukla, who passed away 26 January 2013 on his travel to New Delhi, India to receive the prestigious Hind Rattan (Jewel of India) award. Padma was born in Tulapur, Uttar Pradesh, India, 7 July 1950, where he grew up and got his education. He received a PhD degree in Physics at the Banaras Hindu University, Varanasi, Uttar Pradesh, India, in 1972, under the supervision of late Prof. R. N. Singh, and a second PhD degree in Theoretical Plasma Physics from Umeå University in Sweden in 1975, under the supervision of Prof. Lennart Stenflo. He worked at the Faculty of Physics & Astronomy, Ruhr-University Bochum, Germany since January 1973, where he was a permanent faculty member and Professor of International Affairs, a position that was created for him to honour his international accomplishments and reputation.

  4. Nuclear Data Sheets for A = 192

    SciTech Connect

    Baglin, Coral M.

    2012-08-15

    Experimental structure and decay data for all nuclei with mass A=192 (Ta, W, Re, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Po, At) have been evaluated. This evaluation, covering data received by 15 June 2012, supersedes the 1998 evaluation by C. M. Baglin (Nuclear Data Sheets84, 717 (1998), literature cutoff August 1998) and the subsequent inclusion in the ENSDF database of the new nuclide {sup 192}At (C. M. Baglin, literature cutoff 16 May 2006). It also incorporates the current evaluation of superdeformed-band information by B. Singh. Since the last publication, {sup 192}Ta, {sup 192}W and {sup 192}At have been observed, and an isomeric state has been identified in {sup 192}Re. The {epsilon} decay of {sup 192}Au has been studied using a multidetector array resulting in an extensively revised level scheme for {sup 192}Pt.

  5. No-signaling, perfect bipartite dichotomic correlations and local randomness

    SciTech Connect

    Seevinck, M. P.

    2011-03-28

    The no-signaling constraint on bi-partite correlations is reviewed. It is shown that in order to obtain non-trivial Bell-type inequalities that discern no-signaling correlations from more general ones, one must go beyond considering expectation values of products of observables only. A new set of nontrivial no-signaling inequalities is derived which have a remarkably close resemblance to the CHSH inequality, yet are fundamentally different. A set of inequalities by Roy and Singh and Avis et al., which is claimed to be useful for discerning no-signaling correlations, is shown to be trivially satisfied by any correlation whatsoever. Finally, using the set of newly derived no-signaling inequalities a result with potential cryptographic consequences is proven: if different parties use identical devices, then, once they have perfect correlations at spacelike separation between dichotomic observables, they know that because of no-signaling the local marginals cannot but be completely random.

  6. Big Bang Day: 5 Particles - 4. The Neutrino

    ScienceCinema

    None

    2016-07-12

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". It's the most populous particle in the universe. Millions of these subatomic particles are passing through each one of us. With no charge and virtually no mass they can penetrate vast thicknesses of matter without any interaction - indeed the sun emits huge numbers that pass through earth at the speed of light. Neutrinos are similar to the more familiar electron, with one crucial difference: neutrinos do not carry electric charge. As a result they're extremely difficult to detect . But like HG Wells' invisible man they can give themselves away by bumping into things at high energy and detectors hidden in mines are exploiting this to observe these rare interactions.

  7. The dimensionality of defense-mechanism parcels in the Defense Style Questionnaire-40.

    PubMed

    Wilkinson, Wayne W; Ritchie, Timothy D

    2015-03-01

    The Defense Style Questionnaire-40 (DSQ-40; Andrews, Singh, & Bond, 1993) uses pairs of items to measure 20 individual defense mechanisms. In a statistical sense, these item pairs represent parcels and are subject to the standards of unidimensionality demanded of parcels in general. Using a 2-facet modeling approach (N = 672), the present study examined the dimensionality of the defense-mechanism parcels in the DSQ-40 and found that the majority of the parcels did not satisfy the criteria for unidimensionality. In addition, the original 3-factor model of defense styles was not tenable with the present data. Overall, the results suggest caution when attempting to assess individual defense mechanisms using the DSQ-40.

  8. B2 RNA and 7SK RNA, RNA polymerase III transcripts, have a cap-like structure at their 5' end.

    PubMed Central

    Shumyatsky, G P; Tillib, S V; Kramerov, D A

    1990-01-01

    We found that hydrolysates of poly(A)+ RNA from Ehrlich ascites carcinoma cells which were transcribed by RNA polymerase III contained an unusual component designated as X. It was part of B2 RNA representing a transcript of B2 retroposon, typical of rodents. The component X possesses a cap-like structure, xppp5'G, where x has a non-nucleotide structure. About half of all B2 RNAs contained this group at the 5' end. Previously, Epstein et al. (1) detected a similar structure at the 5' end of small nuclear U6 RNA. Later, Singh and Reddy (2) showed methyl to be the blocking group in the component x of U6 RNA. Besides B2 RNA, we found 5' ends containing methyl groups in 7SK RNA. Images PMID:1700854

  9. Career involvement and family involvement as moderators of relationships between work-family conflict and withdrawal from a profession.

    PubMed

    Greenhaus, J H; Parasuraman, S; Collins, K M

    2001-04-01

    This study extended prior analyses by J. H. Greenhaus, K. M. Collins, R. Singh, and S. Parasuraman (1997) by examining relationships between 2 directions of work-family conflict (work-to-family conflict and family-to-work conflict) and withdrawal from public accounting. The sample consisted of 199 members of the American Institute of Certified Public Accountants (135 men and 64 women) who were married or in a long-term relationship and who had 1 or more children. It was found that work-to-family conflict (but not family-to-work conflict) was positively related to withdrawal intentions. In addition, relationships of work-to-family conflict with withdrawal intentions and withdrawal behavior were stronger for individuals who were relatively uninvolved in their careers than for those who were highly involved in their careers. The implications of the findings for future research are discussed.

  10. Nuclear Data Sheets for A=40

    NASA Astrophysics Data System (ADS)

    Chen, Jun

    2017-02-01

    The experimental nuclear structure data and decay data are evaluated for the known nuclides of mass 40 (Mg, Al, Si, P, S, Cl, Ar, K, Ca, Sc, Ti). Detailed evaluated nuclear structure information is presented with the best values recommended for level energies, half-lives, γ-ray energies and intensities, decay properties (energies, intensities and placement of radiations), and other spectroscopic data. The 40Ca and 40K nuclides remain as the most extensively studied from many different reactions and decays; no excited states are known in 40Mg, 40Al, 40P and 40Ti. This work supersedes the earlier full evaluation of A=40 by J. Cameron and B. Singh (2004Ca38).

  11. Analytical Modeling for Mechanical Strength Prediction with Raman Spectroscopy and Fractured Surface Morphology of Novel Coconut Shell Powder Reinforced: Epoxy Composites

    NASA Astrophysics Data System (ADS)

    Singh, Savita; Singh, Alok; Sharma, Sudhir Kumar

    2016-06-01

    In this paper, an analytical modeling and prediction of tensile and flexural strength of three dimensional micro-scaled novel coconut shell powder (CSP) reinforced epoxy polymer composites have been reported. The novel CSP has a specific mixing ratio of different coconut shell particle size. A comparison is made between obtained experimental strength and modified Guth model. The result shows a strong evidence for non-validation of modified Guth model for strength prediction. Consequently, a constitutive modeled equation named Singh model has been developed to predict the tensile and flexural strength of this novel CSP reinforced epoxy composite. Moreover, high resolution Raman spectrum shows that 40 % CSP reinforced epoxy composite has high dielectric constant to become an alternative material for capacitance whereas fractured surface morphology revealed that a strong bonding between novel CSP and epoxy polymer for the application as light weight composite materials in engineering.

  12. Usefulness of the Modified NRCS-CN Method for the Assessment of Direct Runoff in a Mountain Catchment

    NASA Astrophysics Data System (ADS)

    Wałęga, Andrzej; Rutkowska, Agnieszka

    2015-10-01

    The aim of this study was to evaluate the usefulness of modified methods, developed on the basis of NRCS-CN method, in determining the size of an effective rainfall (direct runoff). The analyses were performed for the mountain catchment of the Kamienica river, right-hand tributary of the Dunajec. The amount of direct runoff was calculated using the following methods: (1) Original NRCS-CN model, (2) Mishra—Singh model (MS model), (3) Sahu Mishra Eldho model (SME model), (4) Sahu 1-p model, (5) Sahu 3-p model, and (6) Q_base model. The study results indicated that the amount of direct runoff, determined on the basis of the original NRCS-CN method, may differ significantly from the actually observed values. The best results were achieved when the direct runoff was determined using the SME and Sahu 3-p model.

  13. Inertia in Friedmann Universes with variable and

    NASA Astrophysics Data System (ADS)

    Sultana, J.; Kazanas, D.

    2015-09-01

    In light of the recent interest in dynamical dark energy models based on a cosmology with varying gravitational and cosmological parameters and , we present here a model of inertia in a type of Friedmann universe with ; being the dimensionless scale factor, that was recently studied by Singh et al. (Astrophys. Space Sci. 345:213, 2013). The proposed Machian model of inertia utilizes the curved space generalization of Sciama's law of inertial induction, which is based on the analogy between the retarded far fields of electrodynamics and those of gravitation, and expresses the total inertial force on an accelerating mass in terms of contributions from all matter in the observable Universe. We show that for a varying Friedmann model with , inertial induction alone can account for the total inertial force on the accelerating mass. We then compare this cosmological model with current observational constraints for the variation of.

  14. Energy levels, radiative rates and lifetimes for transitions in Br-like ions with 38 ⩽ Z ⩽ 42

    NASA Astrophysics Data System (ADS)

    Aggarwal, Kanti M.; Keenan, Francis P.

    2014-12-01

    Energy levels and radiative rates for transitions in five Br-like ions (Sr IV, Y V, Zr VI, Nb VII and Mo VIII) are calculated with the general-purpose relativistic atomic structure package (grasp). Extensive configuration interaction has been included and results are presented among the lowest 31 levels of the 4s24p5, 4s24p44d and 4s4p6 configurations. Lifetimes for these levels have also been determined, although unfortunately no measurements are available with which to compare. However, recently theoretical results have been reported by Singh et al (2013 Phys. Scr. 88 035301) using the same grasp code. But their reported data for radiative rates and lifetimes cannot be reproduced and show discrepancies of up to five orders of magnitude with the present calculations.

  15. On the amplitude of dust-density waves in inhomogeneous dusty plasmas

    NASA Astrophysics Data System (ADS)

    Tadsen, Benjamin; Greiner, Franko; Piel, Alexander

    2017-03-01

    Density waves in a cloud of submicron dust particles confined in an rf plasma are examined with respect to their amplitude. The plasma shows a strong inhomogeneity in its densities and the dust particle charge. An ion density gradient appears due to ambipolar diffusion and leads to a dust charge gradient provided by charge depletion. Using dust-density wave frequency and wave number as a diagnostic for the plasma parameters, it is found that the wave amplitude increases or decreases as the wave travels into regions with decreasing or increasing particle charge. The experimental amplitude profile is similar to the theoretical curve predicted by a formula from Singh and Rao [Phys. Plasmas 6, 3157-3162 (1999)].

  16. Tuning quantum properties in bilayer ruthenates

    NASA Astrophysics Data System (ADS)

    Ke, Xianglin

    The mutual coupling among spin, charge, lattice and orbital degrees of freedom in transition-metal oxide materials often leads to the competition of various types of energetic states. This makes such materials dramatically susceptible to external parameters, giving rise to novel physical properties and rich phase diagrams. In this talk, I shall use a bilayer ruthenate, Ca3Ru2O7, as an example to discuss the emergent phenomena achieved by systematically tuning materials magnetic and electronic properties via chemical doping, magnetic field, and pressure. I shall show that this system provides a rare opportunity to investigate the interplay between correlated metal and Mott insulator. This work was done in collaboration with M. Zhu, T. Tao, S. D. Mahanti, Z. Q. Mao, J. Peng, T. Hong, W. Tian, H. Cao, C. R. dela Cruz, D. Singh, and K. Prokes.

  17. Super Quantum Discord for X-type States

    NASA Astrophysics Data System (ADS)

    Li, Tao; Ma, Teng; Wang, Yaokun; Fei, Shaoming; Wang, Zhixi

    2015-02-01

    Weak measurement is a new way to manipulate and control quantum systems. Different from projection measurement, weak measurement only makes a small change in status. Applying weak measurement to quantum discord, Singh and Pati proposed a new kind of quantum correlations called "super quantum discord (SQD)" [Ann. Phys. 343,141(2014)].Unfortunately, the super quantum discord is also difficult to calculate. There are only few explicit formulae about SQD. We derive an analytical formula of SQD for general X-type two-qubit states, which surpass the conclusion for Werner states and Bell diagonal states. Furthermore, our results reveal more knowledge about the new insight of quantum correlation and give a new way to compare SQD with normal quantum discord. Finally, we analyze its dynamics under nondissipative channels.

  18. Loop quantum cosmology of Bianchi IX: Inclusion of inverse triad corrections

    NASA Astrophysics Data System (ADS)

    Corichi, Alejandro; Karami, Asieh

    2016-06-01

    We consider the loop quantization of the (diagonal) Bianchi type IX cosmological model. We explore different quantization prescriptions that extend the work of Wilson-Ewing and Singh. In particular, we study two different ways of implementing the so-called inverse triad corrections. We construct the corresponding Hamiltonian constraint operators and show that the singularity is formally resolved. We find the effective equations associated with the different quantization prescriptions, and study the relation with the isotropic k = 1 model that, classically, is contained within the Bianchi IX model. Somewhat surprisingly, we find the most natural quantization does not reduce to the k = 1 model. We use geometrically defined scalar observables to explore the physical implications of each of these theories. This is the first part in a series of papers analyzing different aspects of the Bianchi IX model, with inverse corrections, within loop quantum cosmology (LQC).

  19. Vertex amplitudes in spin foam loop quantum cosmology

    NASA Astrophysics Data System (ADS)

    Craig, David

    2016-03-01

    We discuss properties of the vertex expansion for homogeneous, isotropic loop quantum cosmological models sourced by a massless, minimally coupled scalar field, which in this model plays the role of an internal matter ``clock''. We show that the vertex expansion, first written down by Ashtekar, Campiglia and Henderson, must be thought of as a short-time expansion in the sense that the amplitude for volume transitions is constrained both by the order of the expansion and by the elapsed scalar field. To calculate the amplitude for significant volume changes or between large differences in the value of the scalar field requires the expansion be evaluated to very high order. This contribution describes work in collaboration with P. Singh.

  20. A novel endohedral silicon nanotube

    NASA Astrophysics Data System (ADS)

    Zhang, Chuan-Hui; Shen, Jiang

    2009-08-01

    Using first principles calculations, we find that novel M@SWSiNTs are stabilized due to their endohedral transition metal atoms, and that their structures are more flexible than SiNTs with hexagonal prism structures [A.K. Singh, V. Kumar, Y. Kawazoe, J. Mat. Chem. 14 (2004) 555]. Because of the strong hybridization between metal and Si orbitals the charge flows freely, as in a crystal, making all M@SWSiNTs studied metallic. Many energy levels are occupied by electrons in hybridized orbitals, resulting in a quasi-continuum energy band. All M@SWSiNTs are good electron acceptors, and most of them are good electron donors. M@SWSiNTs open the possibility of developing novel silicon nanomaterials that could be of interest for industrial applications.

  1. Metallacarboranes: Towards promising hydrogen storage metal organic framework

    NASA Astrophysics Data System (ADS)

    Singh, Abhishek; Sadrzadeh, Arta; Yakobson, Boris

    2011-03-01

    Using first principles calculations we show the high hydrogen storage capacity of metallacarboranes, where the transition metal (TM) atoms bind hydrogen via Kubas interaction. The average binding energy of ~ 0.3 eV/H favorably lies within the reversible adsorption range The Sc and Ti are found to be the optimum metal atoms maximizing the number of stored H2 molecules. Depending upon the structure, metallacarboranes can adsorb up to 8 wt% of hydrogen, which exceeds DOE goal for 2015. Being integral part of the cage, TMs do not suffer from the aggregation problem. Furthermore, the presence of carbon atom in the cages permits linking the metallacarboranes to form metal organic frameworks (MOF), thus able to adsorb hydrogen via Kubas interaction, in addition to van der Waals physisorption. A. K. Singh, A. Sadrzadeh, and B. I. Yakobson, Metallacarboranes: Toward Promising Hydrogen Storage Metal Organic Frameworks, JACS 132,14126 (2010).

  2. How to Obtain Accurate Equations-of-State by Eliminating the Effects of Deviatoric Stresses

    NASA Astrophysics Data System (ADS)

    Chesnut, Gary; Schiferl, David

    2003-03-01

    In the field of static high-pressure research, it is common to find disagreements in the data between individual experiments. For example, there are many disagreements about crystal structures and volume discontinuities at phase transitions. Of course, there are many causes that give rise to these problems. The intrinsic properties of some materials can be the source of the confusion. However, there is another source, which affects every static high-pressure experiment - deviatoric stress. This problem has been well defined in the last decade. In particular, A. K. Singh et al has derived the equations of the deviatoric stresses for all the crystallographic structures. However, it only takes a moment to realize the difficulty in solving these equations for all but the simplest structures. Fortunately, there is a way around the problem of deviatoric stress - Magic Angle X-ray Diffraction.

  3. Neutron diffraction study of the BiFeO₃ spin cycloid at low temperature.

    PubMed

    Herrero-Albillos, Julia; Catalan, Gustau; Rodriguez-Velamazan, José Alberto; Viret, Michel; Colson, Dorothée; Scott, James F

    2010-06-30

    The reported observation of two anomalies in the intensity of the magnon Raman peaks of BiFeO₃ at 140 and 200 K (Singh et al 2008 J. Phys.: Condens. Mater 20 252203; Cazayous et al 2008 Phys. Rev. Lett. 101 037601) led to the hypothesis that such anomalies might originate from a spin reorientation transition. In order to test this hypothesis, we have used temperature-dependent neutron diffraction to track the evolution of the magnetic configuration in single crystals of BiFeO₃. Our results indicate that there is no average reorientation of the spins. This suggests that the magnon anomalies may instead be related to the freezing of modes that do not alter the average projection of the spins over the plane of the cycloid, as also reported for multiferroic TbMnO₃ (Senff et al 2006 J. Phys.: Condens. Mater 18 2069).

  4. Triclinic modification of N-[(1,1-di-methyl-ethoxy)carbon-yl]-3-[(R)-prop-2-en-1-ylsulfin-yl]-(R)-alanine ethyl ester at 120 (1) K.

    PubMed

    Singh, Suneel P; Verdu, Marcus J; Lough, Alan J; Schwan, Adrian L

    2009-05-23

    There are two independent mol-ecules in the asymmetric unit of the title compound, C(13)H(23)NO(5)S. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link mol-ecules into two independent one-dimensional chains along [100]. The crystal studied was found to be a non-merohedral twin with a ratio of 0.615 (6):0.385 (1) for the refined components. At 200 (1) K [Singh et al. (2009 ▶). Acta Cryst. E65, o1385-o1386] the crystal structure of the title compound contains one disordered mol-ecule in the asymmetric unit of a monoclinic unit cell.

  5. Optical spectroscopy of the Triangular Lattice Antiferromagnets CuCrO2 and α-CaCr2O4

    NASA Astrophysics Data System (ADS)

    Schmidt, Michael; Wang, Zhe; Mayr, F.; Toth, S.; Lake, B.; Islam, A. T. M. N.; Tsurkan, V.; Loidl, A.; Deisenhofer, J.

    2012-02-01

    We will compare and discuss our results obtained by optical spectroscopy on CuCrO2 and α-CaCr2O4. While CuCrO2 is famous for its multiferroicity [1], in α-CaCr2O4 a polarization can only be observed under the application of electric or magnetic field, despite having a closely related structure [2]. At near infrared and visible light frequencies we observe Cr^3+ crystal field absorptions and below TN excitons and exciton-magnon-transitions appear. The width of these exciton-magnon transitions is analyzed with respect to the existence of Z2 vortices as proposed by Kojima et al. [3]. [4pt] [1] S. Seki et al., Phys. Rev. Lett. 101, 067240 (2008)[0pt] [2] K. Singh et al., Phys. Rev. B 84, 064129 (2011)[0pt] [3] N. Kojima et al., J. Phys. Soc. Jpn. 62, 4137 (1993)

  6. Neutron diffraction study of the BiFeO3 spin cycloid at low temperature

    NASA Astrophysics Data System (ADS)

    Herrero-Albillos, Julia; Catalan, Gustau; Rodriguez-Velamazan, José Alberto; Viret, Michel; Colson, Dorothée; Scott, James F.

    2010-06-01

    The reported observation of two anomalies in the intensity of the magnon Raman peaks of BiFeO3 at 140 and 200 K (Singh et al 2008 J. Phys.: Condens. Mater 20 252203; Cazayous et al 2008 Phys. Rev. Lett. 101 037601) led to the hypothesis that such anomalies might originate from a spin reorientation transition. In order to test this hypothesis, we have used temperature-dependent neutron diffraction to track the evolution of the magnetic configuration in single crystals of BiFeO3. Our results indicate that there is no average reorientation of the spins. This suggests that the magnon anomalies may instead be related to the freezing of modes that do not alter the average projection of the spins over the plane of the cycloid, as also reported for multiferroic TbMnO3 (Senff et al 2006 J. Phys.: Condens. Mater 18 2069).

  7. Chemi- and physisorption of hydrogen on graphitic substrates

    NASA Astrophysics Data System (ADS)

    Yakobson, Boris; Singh, Abhishek; Lu, Jianxin; Ribas, Morgana

    2010-03-01

    We evaluate the possibilities of hydrogen storage on graphitic substrates by chemical and physical sorption using multiscale modeling. Detailed thermodynamic analysis based on ab initio calculations of chemisorptions via catalytic spillover shows that the catalyst saturation and improved C-H binding energies are the key to enhanced storage [1]. The estimation of amount of physisorbed hydrogen under the ambient condition in 3D-foams using grand canonical Monte Carlo simulations demands judicious choice of interaction potential and incorporation of quantum corrections due to large thermal de Brogile wavelength. We will show that the storage capacities (chemi- or physisorption) in graphitic materials can meet the DOE 2015 targets. [4pt] [1] A. K. Singh, M. A. Ribas, and Boris I. Yakobson, ACS Nano, 3, 1657 (2009).

  8. Critical slowing down of spin fluctuations in BiFeO3

    NASA Astrophysics Data System (ADS)

    Scott, J. F.; Singh, M. K.; Katiyar, R. S.

    2008-10-01

    In earlier work we reported the discovery of phase transitions in BiFeO3 evidenced by divergences in the magnon light-scattering cross-sections at 140 and 201 K (Singh et al 2008 J. Phys.: Condens. Matter 20 252203) and fitted these intensity data to critical exponents α = 0.06 and α' = 0.10 (Scott et al 2008 J. Phys.: Condens. Matter 20 322203), under the assumption that the transitions are strongly magnetoelastic (Redfern et al 2008 at press) and couple to strain divergences through the Pippard relationship (Pippard 1956 Phil. Mag. 1 473). In the present paper we extend those criticality studies to examine the magnon linewidths, which exhibit critical slowing down (and hence linewidth narrowing) of spin fluctuations. The linewidth data near the two transitions are qualitatively different and we cannot reliably extract a critical exponent ν, although the mean field value ν = 1/2 gives a good fit near the lower transition.

  9. The termites of Early Eocene Cambay amber, with the earliest record of the Termitidae (Isoptera).

    PubMed

    Engel, Michael S; Grimaldi, David A; Nascimbene, Paul C; Singh, Hukam

    2011-01-01

    The fauna of termites (Isoptera) preserved in Early Eocene amber from the Cambay Basin (Gujarat, India) are described and figured. Three new genera and four new species are recognized, all of them Neoisoptera - Parastylotermes krishnai Engel & Grimaldi, sp. n. (Stylotermitidae); Prostylotermes kamboja Engel & Grimaldi, gen. et sp. n. (Stylotermitidae?); Zophotermes Engel, gen. n., with Zophotermes ashoki Engel & Singh, sp. n. (Rhinotermitidae: Prorhinotermitinae); and Nanotermes isaacae Engel & Grimaldi, gen. et sp. n. (Termitidae: Termitinae?). Together these species represent the earliest Tertiary records of the Neoisoptera and the oldest definitive record of Termitidae, a family that comprises >75% of the living species of Isoptera. Interestingly, the affinities of the Cambay amber termites are with largely Laurasian lineages, in this regard paralleling relationships seen between the fauna of bees and some flies. Diversity of Neoisoptera in Indian amber may reflect origin of the amber deposit in Dipterocarpaceae forests formed at or near the paleoequator.

  10. Elasticity of Tantalum to 105 Gpa using a stress and angle-resolved x-ray diffraction

    SciTech Connect

    Cynn, H; Yoo, C S

    1999-08-11

    Determining the mechanical properties such as elastic constants of metals at Mbar pressures has been a difficult task in experiment. Following the development of anisotropic elastic theory by Singh et al. [l], Mao et a1.[2] have recently developed a novel experimental technique to determine the elastic constants of Fe by using the stress and energy-dispersive x-ray diffraction (SEX). In this paper, we present an improved complementary technique, stress and angle-resolved x-ray diffraction (SAX), which we have applied to determine the elastic constants of tantalum to 105 GPa. The extrapolation of the tantalum elastic data shows an excellent agreement with the low-pressure ultrasonic data [3]. We also discuss the improvement of this SAX method over the previous SEX. [elastic constant, anisotropic elastic theory, angle-dispersive synchrotron x-ray diffraction, mechanical properties

  11. Refraining Maternal Health Role of Ayurveda in Public Health Care

    PubMed Central

    Singh, Anuradha

    2008-01-01

    Anuradha Singh is a scientist with National Institute of Science, Technology and Development Studies (CSIR) doing research on the theory and practice of Ayurveda. She has authored a book and several research papers on crossroads of Science and Indian Medical Traditions, Philosophical Foundations of Classical Medical Theories and Maternal Health & Ayurveda. She is also a founder member of Lok Swasthya Parampara Samvardhana Samiti (LSPSS) a network of individuals and NGOs working for the development and revitalization of Indian systems of health care. She was a resource person for MATRIKA and also an active member of its Advisory Board. She shares with her fellow contributors (of this issue) the conviction that Ayurveda, as a preventive and curative health system, can be a panacea to all that ails the humans, animals and the plant kingdom. PMID:22557291

  12. Refraining maternal health role of ayurveda in public health care.

    PubMed

    Singh, Anuradha

    2008-07-01

    Anuradha Singh is a scientist with National Institute of Science, Technology and Development Studies (CSIR) doing research on the theory and practice of Ayurveda. She has authored a book and several research papers on crossroads of Science and Indian Medical Traditions, Philosophical Foundations of Classical Medical Theories and Maternal Health & Ayurveda. She is also a founder member of Lok Swasthya Parampara Samvardhana Samiti (LSPSS) a network of individuals and NGOs working for the development and revitalization of Indian systems of health care. She was a resource person for MATRIKA and also an active member of its Advisory Board. She shares with her fellow contributors (of this issue) the conviction that Ayurveda, as a preventive and curative health system, can be a panacea to all that ails the humans, animals and the plant kingdom.

  13. Determination of the stoichiometry, structure, and distribution in living cells of protein complexes from analysis of single-molecular-complexes FRET

    NASA Astrophysics Data System (ADS)

    Stoneman, Michael R.; Patowary, S.; Roesch, M. T.; Singh, D. R.; Strogolov, V.; Oliver, J. A.; Raicu, V.

    2011-03-01

    Advances in two-photon microscopy with spectral resolution (TPM-SR) and the development of a simple theory of Förster Resonance Energy Transfer (FRET) for single molecular complexes recently lead to the development of a novel method for the determination of structure and localization in living cells of membrane protein complexes (Raicu et al., Nature Photon., 3, 2009). An appealing feature of this method is its ability to provide such important information while being unaffected by spurious signals originating from stochastic FRET (Singh and Raicu, Biophys. J., 98, 2010). We will present the results obtained from our recent studies of trimeric FRET calibration standards expressed in the cytoplasm of Chinese hamster ovary (CHO) cells, as well as a model G protein-coupled receptor expressed in the membrane of yeast. Emphasis will be placed on the measurement and analysis of single-molecular-complex FRET data for determination of the quaternary structure of some proteins (or the protein complex structure).

  14. A New Framework for Adptive Sampling and Analysis During Long-Term Monitoring and Remedial Action Management

    SciTech Connect

    Minsker, Barbara

    2005-06-01

    Yonas Demissie, a research assistant supported by the project, has successfully created artificial data and assimilated it into coupled Modflow and artificial neural network models. His initial findings show that the neural networks help correct errors in the Modflow models. Abhishek Singh has used test cases from the literature to show that performing model calibration with an interactive genetic algorithm results in significantly improved parameter values. Meghna Babbar, the third research assistant supported by the project, has found similar results when applying an interactive genetic algorithms to long-term monitoring design. She has also developed new types of interactive genetic algorithms that significantly improve performance. Gayathri Gopalakrishnan, the last research assistant who is partially supported by the project, has shown that sampling branches of phytoremediation trees is an accurate approach to estimating soil and groundwater contaminations in areas surrounding the trees at the Argonne 317/319 site.

  15. Mitochondria in health and disease - 3rd annual conference of society for mitochondrial research and medicine - 19-20 December 2013 - Bengaluru, India.

    PubMed

    Durhuus, Jon Ambæk; Desler, Claus; Rasmussen, Lene Juel

    2015-01-01

    The primary role of mitochondria was long considered to be production of cellular energy. However, as the understanding of mitochondria in disease is ever expanding, so is their additional function for a healthy organism. Mitochondrial dysfunction is linked to a range of pathologies, including cancer, neurodegenerative disorders, premature aging, diabetes and muscular diseases. Mitochondrial diseases can be hard to diagnose and treat and, therefore, interdisciplinary research and communication are important. The Third Annual Conference of Society for Mitochondrial Research and Medicine - India (SMRM) was titled "Mitochondria in Health and Disease". The conference was organized by Gayathri N, K Thangaraj, and KK Singh and was held at the National Institute of Mental Health & Neuro Sciences (NIMHANS) in Bangalore, India, from the 19th to 20th of December 2013. The meeting featured internationally renowned speakers within the field of mitochondrial research and medicine with the goal of bridging the gap between basic and clinical researchers. This review summarizes key outcomes of the conference.

  16. Comparative Evaluation of Electronic Apex Locators and Radiovisiography for Working Length Determination in Primary Teeth in vivo

    PubMed Central

    Singh, Neerja; Rathore, Monika S; Tandon, Shobha; Rajkumar, Balakrishnan

    2016-01-01

    ABSTRACT Aims: The aim of this study was to evaluate the effectiveness of two different varieties of electronic apex locators and radiovisiography (RVG) for working length determination in primary teeth. Materials and methods: A total of 30 primary teeth indicated for pulpectomy in children aged 3 to 8 years were randomly selected and subjected to working length determination using two varieties of electronic apex locators and RVG separately. The data were then subjected to statistical analysis. Results: A very strong correlation between electronic measurement methods and RVG length was observed. Conclusion: Radiovisiography and apex locators are equally effective in determining working length in primary teeth. How to cite this article: Abdullah A, Singh N, Rathore MS, Tandon S, Rajkumar B. Comparative Evaluation of Electronic Apex Locators and Radiovisiography for Working Length Determination in Primary Teeth in vivo. Int J Clin Pediatr Dent 2016;9(2):118-123. PMID:27365931

  17. Early-time plasma expansion characteristics of ionized clouds in the ionosphere

    NASA Technical Reports Server (NTRS)

    Schunk, R. W.; Szuszczewicz, E. P.

    1988-01-01

    A series of Vlasov-Poisson simulations were conducted with barium and lithium gas mixtures expanding into an O(+) background plasma, with the values for the Ba(+)/Li(+) composition ratios and the cloud/background density ratios based on anticipated release values in the upcoming Combined Release and Radiation Effects Satellite (CRRES) experiment. The results obtained on the early-time expansion of high-density Ba(+), Li(+), and Ba(+)-Li(+) plasma clouds into low-density O(+) background plasma complement the H(+)-O(+) expansions of Gurevich et al. (1973) and Singh and Schunk (1982, 1983), and the characteristic features observed apply to the very-early-time expansion phase of the CRRES releases.

  18. The Hidden Side of a Laser Beam

    NASA Astrophysics Data System (ADS)

    Moore, Jared W.; Vyas, Reeta; Singh, Surendra

    In a frequency mixing experiment in Jan's lab, where one of us (SS) was visiting during 1989-90, a linearly polarized Ar-ion beam was accidentally directed onto a crossed polarizer. At the output of the polarizer we saw a four lobe pattern although the incident beam had the lowest order Hermite-Gaussian beam profile [HG00]. We attributed it to a small mixture of HG11 mode in the laser output and moved on. A few years later, when this phenomenon was encountered in a different context, a careful examination revealed the secret side of a gaussian beam - Maxwell's equations require linearly polarized laser beams to have a small mixture of cross-polarization component [Erikson and Singh, Phys Rev. E 49, 5778]. This effect is described here.

  19. Effect of microwave power on kinetics and characteristics of microwave vacuum-dried longan (Dimocarpus longan Lour.) pulp.

    PubMed

    Su, Dongxiao; Zhang, Mingwei; Wei, Zhencheng; Tang, Xiaojun; Zhang, Ruifen; Liu, Lei; Deng, Yuanyuan

    2015-03-01

    The drying kinetics of longan (Dimocarpus longan Lour.) pulp processed by microwave vacuum under different microwave levels (2.67, 5.33, 8.00, and 10.67 W/g) was investigated (pressure controlled at -85 ± 2 kPa) in the present study. It was found that the drying rate of longan pulp was dependent on the microwave power, and the rehydration rate increased from 1.96 to 2.17 with the increase of microwave power from 2.67 to 10.67 W/g. Among nine selected thin layer models, the microwave vacuum drying of longan pulp was well represented by five models, which were Page, Modified Henderson and Pabis, Wang and Singh, Logarithmic, and Midilli models. Furthermore, the results of statistical analysis indicated that the Midilli model could describe the best experimental data. In addition, scanning electron microscope observation showed that the microwave vacuum-dried longan pulp had a porous structure.

  20. A novel dehydration technique for carrot slices implementing ultrasound and vacuum drying methods.

    PubMed

    Chen, Zhi-Gang; Guo, Xiao-Yu; Wu, Tao

    2016-05-01

    A novel drying technique using a combination of ultrasound and vacuum dehydration was developed to shorten the drying time and improve the quality of carrot slices. Carrot slices were dried with ultrasonic vacuum (USV) drying and vacuum drying at 65 °C and 75 °C. The drying rate was significantly influenced by the drying techniques and temperatures. Compared with vacuum drying, USV drying resulted in a 41-53% decrease in the drying time. The drying time for the USV and vacuum drying techniques at 75 °C was determined to be 140 and 340 min for carrot slices, respectively. The rehydration potential, nutritional value (retention of β-carotene and ascorbic acid), color, and textural properties of USV-dried carrot slices are predominately better compared to vacuum-dried carrot slices. Moreover, lower energy consumption was used in the USV technique. The drying data (time versus moisture ratio) were successfully fitted to Wang and Singh model.

  1. Ultrasonic disruption of algae cells

    NASA Astrophysics Data System (ADS)

    King, P. M.; Nowotarski, K.; Joyce, E. M.; Mason, T. J.

    2012-05-01

    During last decade there has been increasing interest in the production of sustainable fuels from microalgae (R.H. Wijffels and M.J. Barbosa, 2010; Singh et al 2011; D.H. Lee 2011). The aim of this project was to determine if algal cells can be ultrasonically disrupted to release lipids for biofuel production. Ultrasonic disruption of two unicellular algal species: Dunnaliella salina and Nannochloropsis oculata was investigated using a 20 kHz probe. Haemocytometer, optical density, UV-Vis, fluoro-spectrophotometer and confocal microscopy results demonstrated complete cell destruction of Dunaliella salina within 16 minutes of sonication. Results obtained for Nannochloropsis oculata differed in that ultrasound dispersed clumped cells with little or no cell disruption, as observed by haemocytometer and confocal microscopy analysis. However, UV-Visible and fluoro-spectrophotometer analysis indicated chlorophyll release following sonication, suggesting some cell disruption had occurred.

  2. Study of naturally occurring Precambrian native iron through high-pressure Mössbauer Spectroscopy up to 10 GPa

    NASA Astrophysics Data System (ADS)

    Chandra, Usha; Parthasarathy, G.

    2009-06-01

    We report here the Mössbauer spectroscopic studies on native iron sample obtained from Proterozoic Mica Schist of Chaibasa SinghBhum craton of Eastern India at ambient condition as well as under high pressure up to 10 GPa using Diamond Anvil Cell and 4:1 methanol -- ethanol mixture as hydrostatic pressure medium. The results were compared with the studies on metallic iron under high pressure [1,2] . A slight variation in isomer shift up to 5.6 GPa and onset of a new peak corresponding to BCC->HCP transformation at 9.1 GPa might indicate the magnitude of impact experienced by the sample before attaining the thermodynamical equilibrium. [1] Pipkorn D.N., Edge C.K., Debrunner P., De Pasquali G., Drickamer H.G. and Fraunfelder H. (1964) 135, 1604. [2] Chandra usha, Mudgal Prerana, Kumar Manoj, Rawat Rajeev, Parthasarathy, Dilawar Nita and Bandyopadhyay A.K. (2005), Hyper. Inter.163, 129.

  3. Big Bang Day: 5 Particles - 1. The Electron

    ScienceCinema

    None

    2016-07-12

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 1. The Electron Just over a century ago, British physicist J.J. Thompson experimenting with electric currents and charged particles inside empty glass tubes, showed that atoms are divisible into indivisible elementary particles. But how could atoms be built up of these so called "corpuscles"? An exciting 30 year race ensued, to grasp the planetary model of the atom with its orbiting electrons, and the view inside the atom was born. Whilst the number of electrons around the nucleus of an atom determines their the chemistry of all elements, the power of electrons themselves have been harnessed for everyday use: electron beams for welding,cathode ray tubes and radiation therapy.

  4. Srivastavanema cynocephali n. sp. (Nematoda, Trichostrongylina, Heligmosomoidea), a parasite of a dermopteran from Indonesia.

    PubMed

    Durette-Desset, M C; Purwaningsih, E

    1999-03-01

    Srivastavanema cynocephali n. sp., a parasite of Cynocephalus variegatus (Dermoptera) from Indonesia, is described. This species is closely related to S. yapi Durette-Desset & Lim Boo Liat, 1975, in the characters of the synlophe at the mid-body and in the shape of the caudal bursa, but it is distinguished by the pattern of the synlophe in the posterior part of the body, very long, thin rays 2 and 3, a less developed genital cone, the absence of a membrane between left and right rays 6, and longer spicules. Its morphology is slightly less specialised than the four previously known species of the genus, which are all parasites of petauristines. The genus Srivastavanema (Singh, 1962) has a systematic position between the Heligmonellinae and the Brevistriatinae. Therefore, it may be a parasite of the Dermoptera which could have secondarily evolved within the Petauristinae. The Dermoptera may have played an important role in the evolution of the Heligmonellinae.

  5. Big Bang Day: 5 Particles - 1. The Electron

    SciTech Connect

    2009-10-07

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 1. The Electron Just over a century ago, British physicist J.J. Thompson experimenting with electric currents and charged particles inside empty glass tubes, showed that atoms are divisible into indivisible elementary particles. But how could atoms be built up of these so called "corpuscles"? An exciting 30 year race ensued, to grasp the planetary model of the atom with its orbiting electrons, and the view inside the atom was born. Whilst the number of electrons around the nucleus of an atom determines their the chemistry of all elements, the power of electrons themselves have been harnessed for everyday use: electron beams for welding,cathode ray tubes and radiation therapy.

  6. Essentiality of early diagnosis of molar incisor hypomineralization in children and review of its clinical presentation, etiology and management.

    PubMed

    Garg, Nishita; Jain, Abhay Kumar; Saha, Sonali; Singh, Jaspal

    2012-09-01

    Molar incisor hypomineralization (MIH) is a common developmental condition resulting in enamel defects in first permanent molars and permanent incisors. It presents at eruption of these teeth. One to four molars, and often also the incisors, could be affected. Since first recognized, the condition has been puzzling and interpreted as a distinct phenomenon unlike other enamel disturbances. Early diagnosis is essential since, rapid breakdown of tooth structure may occur, giving rise to acute symptoms and complicated treatment. The purpose of this article is to review MIH and illustrate its diagnosis and clinical management in young children. How to cite this article: Garg N, Jain AK, Saha S, Singh J. Essentiality of Early Diagnosis of Molar Incisor Hypomineralization in Children and Review of its Clinical Presentation, Etiology and Management. Int J Clin Pediatr Dent 2012;5(3):190-196.

  7. Landscape level analysis of disturbance regimes in protected areas of Rajasthan, India

    NASA Astrophysics Data System (ADS)

    Krishna, P. Hari; Reddy, C. Sudhakar; Singh, Randeep; Jha, C. S.

    2014-04-01

    There is an urgent need to identify the human influence on landscape as disturbance regimes was realized for prioritization of the protected areas. The present study has attempted to describe the landscape level assessment of fragmentation and disturbance index in protected areas of Rajasthan using remote sensing and GIS techniques. Geospatial analysis of disturbance regimes indicates 61.75% of the total PAs are under moderate disturbance index followed by 28.64% and 9.61% under low and high respectively. Among the 28 protected areas- National Chambal WLS, Jaisamand WLS, Kumbhalgarh WLS, Sawai Man Singh WLS, Kailadevi WLS and Bandh Baratha WLS are representing high level of disturbance. The present study has emphasized the moderate to low disturbance regimes in protected areas, which infer low biotic pressure and conservation effectiveness of PA network in Rajasthan. The spatial information generated on PAs is of valuable use for forest management and developing conservation strategies.

  8. Management of pigmented gingiva in child patient: a new era to the pediatric dentistry.

    PubMed

    Namdeoraoji Bahadure, Rakesh; Singh, Parul; Jain, Eesha; Khurana, Heena; Badole, Gautam

    2013-09-01

    Gingival health in the form of size, shape, consistency and appearance are essential components responsible for an attractive smile as well as may cause unpleasant appearance. Melanin pigmentation often occurs in the gingiva as a result of an abnormal deposition of melanin which can compromise the confidence level from the age of childhood. The present article describes and discusses the two cases of gingival melanin pigmentation in 12 and 13 years of female patient and their early surgical intervention with successful follow-up of 9 and 6 months. Patients were instructed to prevent sun exposure, intake of hot foods or beverages like cold drinks, tea, coffee and brushing immediately after surgery. How to cite this article: Bahadure RN, Singh P, Jain E, Khurana H, Badole G. Management of Pigmented Gingiva in Child Patient: A New Era to the Pediatric Dentistry. Int J Clin Pediatr Dent 2013;6(3):197-200.

  9. Management of Pigmented Gingiva in Child Patient: A New Era to the Pediatric Dentistry

    PubMed Central

    Singh, Parul; Jain, Eesha; Khurana, Heena; Badole, Gautam

    2013-01-01

    ABSTRACT Gingival health in the form of size, shape, consistency and appearance are essential components responsible for an attractive smile as well as may cause unpleasant appearance. Melanin pigmentation often occurs in the gingiva as a result of an abnormal deposition of melanin which can compromise the confidence level from the age of childhood. The present article describes and discusses the two cases of gingival melanin pigmentation in 12 and 13 years of female patient and their early surgical intervention with successful follow-up of 9 and 6 months. Patients were instructed to prevent sun exposure, intake of hot foods or beverages like cold drinks, tea, coffee and brushing immediately after surgery. How to cite this article: Bahadure RN, Singh P, Jain E, Khurana H, Badole G. Management of Pigmented Gingiva in Child Patient: A New Era to the Pediatric Dentistry. Int J Clin Pediatr Dent 2013;6(3):197-200. PMID:25206222

  10. Analysis of melting of pyrope compound at high pressures

    NASA Astrophysics Data System (ADS)

    Singh, B. P.; Singh, K. S.

    2012-02-01

    The pressure-volume-temperature relationships have been studied for the pyrope mineral. Values of volumes at simultaneously elevated temperatures and pressures have been evaluated using the Rydberg-Vinet equation of state for isothermal compression and the Singh-Suzuki equation for isobaric thermal expansion. It has been found that the results obtained from these two conventional equations can be reproduced very well by a single equation of state which covers both temperature and pressure changes in solids namely the Hartmann equation of state. Values of volumes at melting temperatures corresponding to elevated pressures have been obtained and found to compare well with the experimental values. It is also found that there exists a simple linear relationship between relative change in melting volume and melting temperature in case of pyrope at different pressures. This is supported by the earlier findings of Anderson in case of forsterite mineral.

  11. Big Bang Day: 5 Particles - 3. The Anti-particle

    ScienceCinema

    None

    2016-07-12

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 3. The Anti-particle. It appears to be the stuff of science fiction. Associated with every elementary particle is an antiparticle which has the same mass and opposite charge. Should the two meet and combine, the result is annihilation - and a flash of light. Thanks to mysterious processes that occurred after the Big Bang there are a vastly greater number of particles than anti-particles. So how could their elusive existence be proved? At CERN particle physicists are crashing together subatomic particles at incredibly high speeds to create antimatter, which they hope will finally reveal what happened at the precise moment of the Big Bang to create the repertoire of elementary particles and antiparticles in existence today.

  12. Nanotechnology in dentistry: Present and future

    PubMed Central

    Bhardwaj, Archana; Bhardwaj, Abhishek; Misuriya, Abhinav; Maroli, Sohani; Manjula, S; Singh, Arvind Kumar

    2014-01-01

    Nanotechnology is the manipulation of matter on the molecular and atomic levels. It has the potential to bring enormous changes into the fields of medicine and dentistry. A day may soon come when nanodentistry will succeed in maintaining near-perfect oral health through the aid of nanorobotics, nanomaterials and biotechnology. However, as with all developments, it may also pose a risk for misuse. Time, economical and technical resources, and human needs will determine the direction this revolutionizing development may take. This article reviews the current status and the potential clinical applications of nanotechnology, nanaomedicine and nanodentistry. How to cite the article: Bhardwaj A, Bhardwaj A, Misuriya A, Maroli S, Manjula S, Singh AK. Nanotechnology in dentistry: Present and future. J Int Oral Health 2013;6(1):121-6. PMID:24653616

  13. Vibration transmission through rolling element bearings. III - Geared rotor system studies

    NASA Technical Reports Server (NTRS)

    Lim, T. C.; Singh, R.

    1991-01-01

    The bearing matrix formulations proposed by Lim and Singh (1990) are extended to analyze the overall dynamics of a geared rotor system which includes a spur gear pair, shafts, rolling-element bearings, a motor, a load, a casing, and flexible or rigid mounts. For this purpose, discrete vibration models are developed and used to predict vibration transmission through the bearings and to investigate the effects of the bearing, casing, and mount dynamics on the dynamic characteristics of the internal rotating system. Analytical predictions show that the theory is capable of predicting the bearing and mount moment transmissibilities in addition to the force transmissibilities. The predicted flexural vibrations of the casing plate are in good agreement with measurements conducted on an experimental set-up that consisted of a high-precision beam and pinion, and four identical rolling element bearings contained in a flexible casing mounted rigidly on a massive foundation.

  14. Preterm Birth: A Primary Etiological Factor for Delayed Oral Growth and Development

    PubMed Central

    Thayath, Muhamad Nishad; Singh, Shikha; Sinha, Anju

    2015-01-01

    ABSTRACT Preterm and low birthweight children comprise approximately 6% of all live births. It is now a well-known fact that premature children experience many oral complications associated with their preterm births. Prematurely born infants have a short prenatal development period and they are prone to many serious medical problems during the neonatal period, which may affect the development of oral tissues. Adverse perinatal factors, premature birth and exceptional early adaptation to extra-uterine life and functional activity may influence dental occlusal development and symmetry in the jaws. Thus, the goal of the present paper is to elucidate further the effect of preterm birth on the development of the dentition. How to cite this article: Zaidi I, Thayath MN, Singh S, Sinha A. Preterm Birth: A Primary Etiological Factor for Delayed Oral Growth and Development. Int J Clin Pediatr Dent 2015;8(3): 215-219. PMID:26628856

  15. Description and evaluation of the QUIC bio-slurry scheme: droplet evaporation and surface deposition

    SciTech Connect

    Zajic, Dragan; Brown, Michael J; Nelson, Matthew A; Williams, Michael D

    2010-01-01

    The Quick Urban and Industrial Complex (QUIC) dispersion modeling system was developed with the goal of improving the transport and dispersion modeling capabilities within urban areas. The modeling system has the ability to rapidly obtain a detailed 3D flow field around building clusters and uses an urbanized Lagrangian random-walk approach to account for transport and dispersion (e.g., see Singh et al., 2008; Williams et al., 2009; and Gowardhan et al., 2009). In addition to wind-tunnel testing, the dispersion modeling system has been evaluated against full-scale urban tracer experiments performed in Salt Lake City, Oklahoma City, and New York City (Gowardhan et al., 2006; Gowardhan et al., 2009; Allwine et al., 2008) and the wind model output to measurements taken in downtown Oklahoma City.

  16. Essentiality of Early Diagnosis of Molar Incisor Hypomineralization in Children and Review of its Clinical Presentation, Etiology and Management

    PubMed Central

    Jain, Abhay Kumar; Saha, Sonali; Singh, Jaspal

    2012-01-01

    Abstract Molar incisor hypomineralization (MIH) is a common developmental condition resulting in enamel defects in first permanent molars and permanent incisors. It presents at eruption of these teeth. One to four molars, and often also the incisors, could be affected. Since first recognized, the condition has been puzzling and interpreted as a distinct phenomenon unlike other enamel disturbances. Early diagnosis is essential since, rapid breakdown of tooth structure may occur, giving rise to acute symptoms and complicated treatment. The purpose of this article is to review MIH and illustrate its diagnosis and clinical management in young children. How to cite this article: Garg N, Jain AK, Saha S, Singh J. Essentiality of Early Diagnosis of Molar Incisor Hypomineralization in Children and Review of its Clinical Presentation, Etiology and Management. Int J Clin Pediatr Dent 2012;5(3):190-196. PMID:25206166

  17. A Method for Calculating Viscosity and Thermal Conductivity of a Helium-Xenon Gas Mixture

    NASA Technical Reports Server (NTRS)

    Johnson, Paul K.

    2006-01-01

    A method for calculating viscosity and thermal conductivity of a helium-xenon (He-Xe) gas mixture was employed, and results were compared to AiResearch (part of Honeywell) analytical data. The method of choice was that presented by Hirschfelder with Singh's third-order correction factor applied to thermal conductivity. Values for viscosity and thermal conductivity were calculated over a temperature range of 400 to 1200 K for He-Xe gas mixture molecular weights of 20.183, 39.94, and 83.8 kg/kmol. First-order values for both transport properties were in good agreement with AiResearch analytical data. Third-order-corrected thermal conductivity values were all greater than AiResearch data, but were considered to be a better approximation of thermal conductivity because higher-order effects of mass and temperature were taken into consideration. Viscosity, conductivity, and Prandtl number were then compared to experimental data presented by Taylor.

  18. Uptake and translocation of Cd[sup 109] by two aquatic ferns in relation to relative toxic response

    SciTech Connect

    Singh, J.; Viswanathan, P.N. ); Gupta, M.; Devi, S. )

    1993-12-01

    Considerable variations exist in the phytotoxic response of different plants to cadmium exposure and uptake as observed in experimental and field studies. Quantitative and qualitative variations in comparative anatomy, physiology and biochemistry could be responsible for selective toxicity. Variations in uptake, translocation, sequestration by cell wall, phytochelation or formation of inclusion bodies have been reported in phytotoxic response to cadmium. Earlier studies by Singh et al. (1991) with the aquatic fern Marsilea minuta Linn showed Cd[sup 2+] induced both ultrastructural lesions and metallothioneins at concentrations above 0.5 ppm. However, another aquatic fern, Ceratopteris thalictroides (L.) Brogn was even more sensitive to the basis of this variation, the comparative uptake and translocation of radioactive Cd[sup 109] by these plans was studied. 11 refs., 1 tab.

  19. Viral contamination of a mosquito cell line, Aedes albopictus, associated with syncytium formation.

    PubMed

    Hirumi, H; Hirumi, K; Speyer, G; Yunker, C E; Thomas, L A; Cory, J; Sweet, B H

    1976-02-01

    Viral contamination associated with syncytium formation in two sbulines of Singh's Aedes albopictus cell cultures was investigated. Electron microscopy of the syncytia revealed the presence of five different types of virus-like particles, which morphologically resembled the parvo-, picorna-, toga-, and orbi-, and bacterial viruses. When a virus-free subline of the A. albopictus cells (SL3) was inoculated with extracts of the syncytium-forming A. albopictus cells, the parvo-, toga-, and orbi-type viral agents were consistently observed. Among these three agents, the togavirus-type agent is most likely responsible for the syncytium induction. Serological examination of the infected cell extract indicated that at least one of three virus-like agents, presumably the togavirus-type agent, was related to Chikungunya. O'nyong-nyong, and Western equine encephalomyelitis viruses (alphaviruses of the Togaviridae), but separable from these.

  20. A Shape-Memory Alloy Thermal Conduction Switch for Use at Cryogenic Temperatures

    NASA Technical Reports Server (NTRS)

    Vaidyanathan, Raj

    2004-01-01

    The following summarizes the activities performed under NASA grant NAG10-323 from September 1, 2002 through September 30, 2004 at the. Univ ersity of Central Florida. A version of this has already been submitt ed for publication in the international journal Swart Materials and S tructures in December 2004. Additionally, a version of this has alrea dy appeared in print in Advances in Cryogenic Engineering, American Institute of Physics, (2004) 50A 26-3; in an article entitled "A Shape Memory Alloy Based Cryogenic Thermal Conduction Switch" by V.B. Krish nan. J.D. Singh. T.R. Woodruff. W.U. Notardonato and R. Vaidyanathan (article is attached at the end of this report).

  1. Map showing depth to bedrock of the Tacoma and part of the Centralia 30' x 60' quadrangles, Washington

    USGS Publications Warehouse

    Buchanan-Banks, Jane M.; Collins, Donley S.

    1994-01-01

    The heavily populated Puget Sound region in the State of Washington has experienced moderate to large earthquakes in the recent past (Nuttli, 1952; Mullineaux and others, 1967). Maps showing thickness of unconsolidated sedimentary deposits are useful aids in delineating areas where damage to engineered structures can result from increased shaking resulting from these earthquakes. Basins containing thick deposits of unconsolidated materials can amplify earthquakes waves and cause far more damage to structures than the same waves passing through bedrock (Singh and others, 1988; Algermissen and others, 1985). Configurations of deep sedimentary basins can also cause reflection and magnification of earthquake waves in ways still not fully understood and presently under investigation (Frankel and Vidale, 1992).

  2. Big Bang Day: 5 Particles - 3. The Anti-particle

    SciTech Connect

    2009-10-07

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 3. The Anti-particle. It appears to be the stuff of science fiction. Associated with every elementary particle is an antiparticle which has the same mass and opposite charge. Should the two meet and combine, the result is annihilation - and a flash of light. Thanks to mysterious processes that occurred after the Big Bang there are a vastly greater number of particles than anti-particles. So how could their elusive existence be proved? At CERN particle physicists are crashing together subatomic particles at incredibly high speeds to create antimatter, which they hope will finally reveal what happened at the precise moment of the Big Bang to create the repertoire of elementary particles and antiparticles in existence today.

  3. In this issue: autoimmunity and innate immunity.

    PubMed

    Bot, Adrian

    2014-01-01

    In this issue of the journal, we host a range of topics relevant to innate immunity as well as certain inflammatory diseases. More specifically, Sanz et al. cover a tantalizing form of death called pyroptosis that leads to inflammation. Samasca et al. provide a brief perspective on celiac disease. Singh and collaborators discuss in detail a newly designed leptin antagonist that could be applicable to colitis treatment. Through a meta-analysis, Wen et al. show that IL-18 gene polymorphism is associated with RA and SLE. Adenovirus-triggered innate immunity is discussed by Chen and Lee. Further, Zheng et al. provide a review of lectin receptors and their importance to anti-microbial immunity. Finally, Rojas et al. discuss tantalizing evidence supporting the fact that endogenous danger motifs such as advanced glycation end products are recognized via a TLR-like molecule and signaling pathway.

  4. Identification of possible structural error in hydrological models

    NASA Astrophysics Data System (ADS)

    Singh, S. K.; Bárdossy, A.; McMillan, H.

    2012-04-01

    Hydrological Models are simplifications and theoretical approximations of complex natural phenomena. Hence, they cannot predict perfectly what happen in natural systems. There are several reasons; some of the main reasons are error in the input data, imperfect model structure, insufficient information for parameter identification etc. The identification of structural error in a complex model is very difficult task. This is especially difficult as the final differences between observation and model results are a combined consequence of the above reasons. In this study we aimed to develop a tool to identify possible model structural error in hydrological model by using the concept of the data depth function. The model was calibrated using the ROPE (Bárdossy and Singh 2008) algorithm and the optimal parameter space was obtained. From N optimal parameter sets N discharge series were obtained and boundary of the convex hull from d-dimensional dataset corresponding N discharge series (DB) is taken for further analysis. A d-dimensional dataset corresponding to the observed discharge (DX) is taken and depth of the each elements of observed discharge is calculated with respect to the boundary of the convex hull from N model discharge series. If there are elements in DX whose depths are zero with respect to the convex hull (DB), then those corresponding to d-days trajectories of the observation for which there is no similarity in any of the model parameterization. These elements can give possible indication for model structure errors. The methodology was demonstrated on two models HYMOD and TopNet in Pelorous catchment of New Zealand. Bárdossy, A. and S. K. Singh (2008). "Robust estimation of hydrological model parameters." Hydrology and Earth System Sciences 12: 1273-1283.

  5. Drying kinetics and mathematical modeling of hot air drying of coconut coir pith.

    PubMed

    Fernando, J A K M; Amarasinghe, A D U S

    2016-01-01

    Drying kinetics of coir pith was studied and the properties of compressed coir pith discs were analyzed. Coir pith particles were oven dried in the range of temperatures from 100 to 240 °C and the rehydration ability of compressed coir pith was evaluated by finding the volume expansion. The optimum drying temperature was found to be 140 °C. Hot air drying was carried out to examine the drying kinetics by allowing the coir pith particles to fluidize and circulate inside the drying chamber. Particle motion within the drying chamber closely resembled the particle motion in a flash dryer. The effective moisture diffusivity was found to increase from 1.18 × 10(-8) to 1.37 × 10(-8) m(2)/s with the increase of air velocity from 1.4 to 2.5 m/s respectively. Correlation analysis and residual plots were used to determine the adequacy of existing mathematical models for describing the drying behavior of coir pith. The empirical models, Wang and Singh model and Linear model, were found to be adequate for accurate prediction of drying behavior of coir pith. A new model was proposed by modifying the Wang and Singh model and considering the effect of air velocity. It gave the best correlation between observed and predicted moisture ratio with high value of coefficient of determination (R(2)) and lower values of root mean square error, reduced Chi square (χ(2)) and mean relative deviation (E%).

  6. Association between Modified Shuttle Walk Test and cardiorespiratory fitness in overweight/obese adults with primary hypertension: EXERDIET-HTA study.

    PubMed

    Jurio-Iriarte, Borja; Gorostegi-Anduaga, Ilargi; Aispuru, G Rodrigo; Pérez-Asenjo, Javier; Brubaker, Peter H; Maldonado-Martín, Sara

    2017-02-07

    The aims of the study were to evaluate the relationship between Modified Shuttle Walk Test (MSWT) with peak oxygen uptake (V˙O2peak) in overweight/obese people with primary hypertension (HTN) and to develop an equation for the MSWT to predict V˙O2peak. Participants (N = 256, 53.9 ± 8.1 years old) with HTN and overweight/obesity performed a cardiorespiratory exercise test to peak exertion on an upright bicycle ergometer using an incremental ramp protocol and the 15-level MSWT. The formula of Singh et al was used as a template to predict V˙O2peak, and a new equation was generated from the measured V˙O2peak-MSWT relationship in this investigation. The correlation between measured and predicted V˙O2peak for Singh et al equation was moderate (r = 0.60, P < .001) with a standard error of the estimate (SEE) of 4.92 mL·kg(-1) minute(-1), SEE% = 21%. The correlation between MSWT and measured V˙O2peak as well as for the new equation was strong (r = 0.72, P < .001) with a SEE of 4.35 mL·kg(-1) minute(-1), SEE% = 19%. These results indicate that MSWT does not accurately predict functional capacity in overweight/obese people with HTN and questions the validity of using this test to evaluate exercise intolerance. A more accurate determination from a new equation in the current study incorporating more variables from MSWT to estimate V˙O2peak has been performed but still results in substantial error.

  7. Crustal Configuration of the Terrace off Trivandrum, Southwestern Continental Margin of India

    NASA Astrophysics Data System (ADS)

    Kurian, J.; Vadakkeyakath, Y.; Bhattacharya, G. C.; Sivaramakrishnan, R.; Sk221 Scientific Team*

    2010-12-01

    The Terrace off Trivandrum (TOT) is an anomalous bathymetric protrusion in the southwestern continental margin of India. Recent studies based on paleogeographic reconstructions have suggested that the Terrace off Trivandrum and the bathymetric notch in the Northern Madagascar Ridge are conjugate features related to India-Madagascar separation. While the nature of crust underlying the Northern Madagascar Ridge is ambiguous, no information is available on the nature of the crust in the Terrace off Trivandrum. In this context, the present study was carried out to understand the crustal configuration of TOT based on recently acquired bathymetry, multi-channel seismic reflection, gravity and magnetic data. The seismic reflection data clearly brings out the block-faulted nature of the basement and presence of a nearly N-S trending wide basement high in the central part of the TOT. This region is characterized by the presence of several prominent high amplitude magnetic anomalies as well as several positive residual gravity anomalies superimposed over a broad negative free-air gravity anomaly. At places, the prominent gravity and magnetic anomalies coincide with the bathymetric features suggesting their probable genesis as volcanic emplacements. In the central part of the TOT, the prominent gravity anomalies coincide with the wide basement high. However, no distinctive basement features are conspicuous in the seismic section corresponding to the prominent magnetic anomalies observed at places over this basement high. Integrated modelling of gravity and magnetic data constrained by seismic reflection information suggests that the crustal configuration of the TOT region is comparable to a thinned continental crust intermingled with intruded / extruded volcanics. *SK221 Scientific Team: M.M. Subramaniam, A. Tyagi, P. Vohat, A. Bhattacharya, V.S.K. Rao, P. Shetkar, R.D. Singh, U.K. Singh, K.V. Swamy, S. Upadhyaya

  8. Inferences on sediment provenance and source weathering using major, trace and Sr-Nd isotopic compositional variations in alluvial sediments from Sirhind, Punjab, India

    NASA Astrophysics Data System (ADS)

    Paul, D.; Amir, M.; Sinha, R.; Singh, A.; Balakrishnan, S.

    2013-12-01

    sediments show less radiogenic Sr and more radiogenic Nd (Higher Himalayan signature) whereas sediments deposited around the post-LGM show more radiogenic Sr and less radiogenic in Nd (Lesser Himalayan signature). These variations can be attributed to decreased monsoon precipitation and larger ice cover over the Higher Himalaya during LGM that reduced Higher Himalayan contribution to the post-LGM samples. Similarly, decreasing glacial cover during Holocene may have resulted in relatively more sediment contribution from the Higher Himalayas giving rise to lower 87Sr/86Sr and higher ɛNd values. The findings of this study are consistent with those from the down-stream (Ghaggar river) core sediments2 and Ganga-Yamuna interfluve sediments1. Sr-Nd compositions coupled with CIA values indicate a dominant control of climate on provenance and source weathering. 1Rahaman, W., S. K. Singh., R. Sinha., and S. K. Tondon (2009), Geology, 37, 559-526. 2Singh, A., D. Paul., S. K. Singh., and R. Sinha (2013), PAGES 4th meeting, Goa, India.

  9. Seismo-electromagnetic phenomena in the western part of the Eurasia-Nubia plate boundary

    NASA Astrophysics Data System (ADS)

    Gonçalves da Silva, Hugo; Bezzeghoud, Mourad; Biagi, Pier; Namorado Rosa, Rui; Salgueiro da Silva, Manuel; Caldeira, Bento; Heitor Reis, Artur; Borges, José Fernando; Tlemçani, Mouhaydine; Manso, Marco

    2010-05-01

    variations of EM properties of the crust/plate in relation with the strain field, and in space in relation with composition and temperature and stress fields. Further, the interplay between atmospheric (and solar) perturbations with crust perturbations will be monitored, to observe geomagnetic perturbations at different locations. Our study will be focused in the analyses of low magnitude earthquakes with M =< 4, these events are frequent in the WENP region, but have been almost completely disregarded in literature [5,6]. [1] J. Borges, A. J. S. Fitas, M. Bezzeghoud, and P. Teves-Costa, Tectonophysics 337, 373 (2001). [2] V. Chauhan, O.P. Singh, V. Kushwah, V. Singh, B. Singh, Journal of Geodynamics 48, 68 (2009). [3] L. Telesca, V. Lapenna, M. Macchiato, and K. Hattori, Earth and Planet. Science Lett. 268, 219 (2008). [4] P. F. Biagi, L. Castellana, T. Maggipinto, D. Loiacono, L. Schiavulli, T. Ligonzo, M. Fiore, E. Suciu, and A. Ermini, Nat. Hazards Earth Syst. Sci. 9, 1551 (2009). [5] A. Rozhnoi , M.S. Solovieva, O.A. Molchanov, and M. Hayakawa, Phys. and Chem. of the Earth 29, 589-598 (2004). [6] K. Hattori, I. Takahashi, C. Yoshino, N. Isezaki, H. Iwasaki, M. Harada, K. Kawabata, E. Kopytenko, Y. Kopytenko, P. Maltsev, V. Korepanov, O. Molchanov, M. Hayakawa, Y. Noda, T. Nagao, S. Uyeda, Physics and Chemistry of the Earth 29, 481-494 (2004).

  10. Managing High-Altitude Pulmonary Edema with Oxygen Alone: Results of a Randomized Controlled Trial.

    PubMed

    Yanamandra, Uday; Nair, Velu; Singh, Surinderpal; Gupta, Amul; Mulajkar, Deepak; Yanamandra, Sushma; Norgais, Konchok; Mukherjee, Ruchira; Singh, Vikrant; Bhattachar, Srinivasa A; Patyal, Sagarika; Grewal, Rajan; Chopra, Bhushan

    2016-12-01

    Yanamandra, Uday, Velu Nair, Surinderpal Singh, Amul Gupta, Deepak Mulajkar, Sushma Yanamandra, Konchok Norgais, Ruchira Mukherjee, Vikrant Singh, Srinivasa A. Bhattachar, Sagarika Patyal, and Rajan Grewal. High-altitude pulmonary edema management: Is anything other than oxygen required? Results of a randomized controlled trial. High Alt Med Biol. 17:294-299, 2016.-Treatment strategies for management of high-altitude pulmonary edema (HAPE) are mainly based on the observational studies with only two randomized controlled trials, thus the practice is very heterogeneous and individualized as per the choice of treating physician. To compare the response to different modalities of therapy in patients with HAPE in a randomized controlled manner. We conducted an open-label, randomized noninferiority trial to compare three modalities of therapy (Therapy 1: supplemental O2 with oral dexamethasone 8 mg q8 hours [n = 42], Therapy 2: supplemental O2 with sustained release oral nifedipine 20 mg q8 hours [n = 41], and Therapy 3: only supplemental O2 [n = 50]). Bed rest was mandated in all patients. The study was conducted in a cohort of previously healthy young lowlander males at an altitude of 3500 m. Baseline characteristics of the patients were comparable in the study arms. Complete response was defined as clinical and radiological resolution of features of HAPE, no oxygen dependency, a normal 6-minute walk test (6MWT) on 2 consecutive days, and normal two-dimensional echocardiography. Results were compared by analysis of variance using SPSS version 16.0. There was no statistical difference in duration of therapy to complete response between the three groups (Therapy 1: 8.1 ± 4.0 days, Therapy 2: 6.7 ± 3.9 days, Therapy 3: 6.8 ± 3.2 days; p = 0.15). There were no deaths in any of the groups. We conclude that oxygen and bed rest alone are adequate therapy for HAPE and that adjuvant pharmacotherapy with either dexamethasone or nifedipine

  11. Low frequency (<1Hz) Large Magnitude Earthquake Simulations in Central Mexico: the 1985 Michoacan Earthquake and Hypothetical Rupture in the Guerrero Gap

    NASA Astrophysics Data System (ADS)

    Ramirez Guzman, L.; Contreras Ruíz Esparza, M.; Aguirre Gonzalez, J. J.; Alcántara Noasco, L.; Quiroz Ramírez, A.

    2012-12-01

    We present the analysis of simulations at low frequency (<1Hz) of historical and hypothetical earthquakes in Central Mexico, by using a 3D crustal velocity model and an idealized geotechnical structure of the Valley of Mexico. Mexico's destructive earthquake history bolsters the need for a better understanding regarding the seismic hazard and risk of the region. The Mw=8.0 1985 Michoacan earthquake is among the largest natural disasters that Mexico has faced in the last decades; more than 5000 people died and thousands of structures were damaged (Reinoso and Ordaz, 1999). Thus, estimates on the effects of similar or larger magnitude earthquakes on today's population and infrastructure are important. Moreover, Singh and Mortera (1991) suggest that earthquakes of magnitude 8.1 to 8.4 could take place in the so-called Guerrero Gap, an area adjacent to the region responsible for the 1985 earthquake. In order to improve previous estimations of the ground motion (e.g. Furumura and Singh, 2002) and lay the groundwork for a numerical simulation of a hypothetical Guerrero Gap scenario, we recast the 1985 Michoacan earthquake. We used the inversion by Mendoza and Hartzell (1989) and a 3D velocity model built on the basis of recent investigations in the area, which include a velocity structure of the Valley of Mexico constrained by geotechnical and reflection experiments, and noise tomography, receiver functions, and gravity-based regional models. Our synthetic seismograms were computed using the octree-based finite element tool-chain Hercules (Tu et al., 2006), and are valid up to a frequency of 1 Hz, considering realistic velocities in the Valley of Mexico ( >60 m/s in the very shallow subsurface). We evaluated the model's ability to reproduce the available records using the goodness-of-fit analysis proposed by Mayhew and Olsen (2010). Once the reliablilty of the model was established, we estimated the effects of a large magnitude earthquake in Central Mexico. We built a

  12. Raman scattering investigations of the interaction of a COV with pure and acid doped ice particles

    NASA Astrophysics Data System (ADS)

    Facq, S.; Oancea, A.; Focsa, C.; Chazallon, B.

    2009-04-01

    (183 K to 273 K). Information at the molecular level on the surface structure can be derived from accompanying changes observed in band shapes and vibrational mode frequencies. The influence of the presence of nitric acid on the molecular interactions with the trapped organic species in ice particles can be also spectroscopically characterized. (1) Gao et al., Science, 2004, 303, 516. (2) Journet et al., J. Phys. Chem. B, 2005, 109, 14112. (3)H. Singh, M. Kanakidou, P.J Crutzen & D.J Jacob, Nature, 1995, 378, 50. (4)H. Singh, Y. Chen, A. Staudt, D. Jacob, D. Blake, B. Heikes & J. Snow, Nature, 2001, 410, 1078. (5)F. Dominé & P.B Shepson, Science, 2002, 297, 1506

  13. Effect of apical hyperosmotic sodium challenge and amiloride on sodium transport in human bronchial epithelial cells from cystic fibrosis donors.

    PubMed

    Rasgado-Flores, Hector; Krishna Mandava, Vamsi; Siman, Homayoun; Van Driessche, Willy; Pilewski, Joseph M; Randell, Scott H; Bridges, Robert J

    2013-12-01

    Hypertonic saline (HS) inhalation therapy benefits cystic fibrosis (CF) patients [Donaldson SH, Bennet WD, Zeman KL, Knowles MR, Tarran R, Boucher RC. N Engl J Med 354: 241-250, 2006; Elkins MR, Robinson M, Rose BR, Harbour C, Moriarty CP, Marks GB, Belousova EG, Xuan W, Bye PT; the National Hypertonic Saline in Cystic Fibrosis (NHSCF) Study Group. N Engl J Med 354: 229-240, 2006]. Surprisingly, these benefits are long-lasting and are diminished by the epithelial Na(+) channel blocker amiloride (Donaldson SH, Bennet WD, Zeman KL, Knowles MR, Tarran R, Boucher RC. N Engl J Med 354: 241-250, 2006). Our aim was to explain these effects. Human bronchial epithelial (hBE) cells from CF lungs were grown in inserts and were used in three experimental approaches: 1) Ussing chambers to measure amiloride-sensitive short-circuit currents (INa); 2) continuous perfusion Ussing chambers; and 3) near "thin-film" conditions in which the airway surface of the inserts was exposed to a small volume (30 μl) of isosmotic or HS solution as the inserts were kept in their incubation tray and were subsequently used to measure INa under isosmotic conditions (near thin-film experiments; Tarran R, Boucher RC. Methods Mol Med 70: 479-492, 2002). HS solutions (660 mosmol/kgH2O) were prepared by adding additional NaCl to the isosmotic buffer. The transepithelial short-circuit current (ISC), conductance (GT), and capacitance (CT) were measured by transepithelial impedance analysis (Danahay H, Atherton HC, Jackson AD, Kreindler JL, Poll CT, Bridges RJ. Am J Physiol Lung Cell Mol Physiol 290: L558-L569, 2006; Singh AK, Singh S, Devor DC, Frizzell RA, van Driessche W, Bridges RJ. Methods Mol Med 70: 129-142, 2002). Exposure to apical HS inhibited INa, GT, and CT. The INa inhibition required 60 min of reexposure to the isosmotic solution to recover 75%. The time of exposure to HS required to inhibit INa was <2.5 min. Under near thin-film conditions, apical exposure to HS inhibited INa, but as

  14. Application of an extension of the MAI method to the Acapulco City, Mexico

    NASA Astrophysics Data System (ADS)

    Contreras, M.; Aguirre, J.

    2001-12-01

    The site effects and the source parameters, are inverted from a Fourier displacement spectra of seismograms that are corrected by geometrical spreading and regional attenuation valid for south center of Mexico(Ordaz and Singh, 1992). We used Genetic Algorithms (GA) to perform the non-linear inversion, like in the MAI method (Moya et al., 2000) . The GA have proved to produce better results than other traditional methods which are frequently trapped in a local minimum. GA is a method that mimics the evolution laws in living creatures. The best individuals reproduce and develop themselves with every generation. In our case each individual correspond to one source and the genes correspond to the source parameters. As in nature, the best source remain and are improved with each iteration. We assume that the site effect at each station are the same independently of the earthquake, because of that we can search for the combination of sources that can produce the smaller standard deviation of the estimated site effects from the different Fourier displacement earthquake spectra. Then we use the obtained site effects to generate a Fourier displacement spectra of an earthquake scenario. With this, we are able to compute the response spectra by means of random vibration theory (Reinoso et al., 1990). We apply this method to four stations located in the Acapulco City, Mexico, that recorded four earthquakes with epicenter located in the Guerrero Subduction Zone. The site effect estimated for one of the stations, called ACAZ, shows a good agreement with the estimated by Chávez-García et al. (1994) using spectral ratios between the ACAZ station and a rock reference site. Also we compare the response spectra from other earthquake, obtained by the former method and the response spectra computed using the acceleration record. We find an acceptable correlation between them. Chávez-García, J. Cuenca y M. Cárdenas (1994), "Estudio complementario de efectos de sitio en Acapulco

  15. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction.

    PubMed

    Smith, Ira J; Godinez, Guillermo L; Singh, Baljit K; McCaughey, Kelly M; Alcantara, Raniel R; Gururaja, Tarikere; Ho, Melissa S; Nguyen, Henry N; Friera, Annabelle M; White, Kathy A; McLaughlin, John R; Hansen, Derek; Romero, Jason M; Baltgalvis, Kristen A; Claypool, Mark D; Li, Wei; Lang, Wayne; Yam, George C; Gelman, Marina S; Ding, Rongxian; Yung, Stephanie L; Creger, Daniel P; Chen, Yan; Singh, Rajinder; Smuder, Ashley J; Wiggs, Michael P; Kwon, Oh-Sung; Sollanek, Kurt J; Powers, Scott K; Masuda, Esteban S; Taylor, Vanessa C; Payan, Donald G; Kinoshita, Taisei; Kinsella, Todd M

    2014-07-01

    Controlled mechanical ventilation (CMV) is associated with the development of diaphragm atrophy and contractile dysfunction, and respiratory muscle weakness is thought to contribute significantly to delayed weaning of patients. Therefore, therapeutic strategies for preventing these processes may have clinical benefit. The aim of the current study was to investigate the role of the Janus kinase (JAK)/signal transducer and activator of transcription 3 (STAT3) signaling pathway in CMV-mediated diaphragm wasting and weakness in rats. CMV-induced diaphragm atrophy and contractile dysfunction coincided with marked increases in STAT3 phosphorylation on both tyrosine 705 (Tyr705) and serine 727 (Ser727). STAT3 activation was accompanied by its translocation into mitochondria within diaphragm muscle and mitochondrial dysfunction. Inhibition of JAK signaling during CMV prevented phosphorylation of both target sites on STAT3, eliminated the accumulation of phosphorylated STAT3 within the mitochondria, and reversed the pathologic alterations in mitochondrial function, reduced oxidative stress in the diaphragm, and maintained normal diaphragm contractility. In addition, JAK inhibition during CMV blunted the activation of key proteolytic pathways in the diaphragm, as well as diaphragm atrophy. These findings implicate JAK/STAT3 signaling in the development of diaphragm muscle atrophy and dysfunction during CMV and suggest that the delayed extubation times associated with CMV can be prevented by inhibition of Janus kinase signaling.-Smith, I. J., Godinez, G. L., Singh, B. K., McCaughey, K. M., Alcantara, R. R., Gururaja, T., Ho, M. S., Nguyen, H. N., Friera, A. M., White, K. A., McLaughlin, J. R., Hansen, D., Romero, J. M., Baltgalvis, K. A., Claypool, M. D., Li, W., Lang, W., Yam, G. C., Gelman, M. S., Ding, R., Yung, S. L., Creger, D. P., Chen, Y., Singh, R., Smuder, A. J., Wiggs, M. P., Kwon, O.-S., Sollanek, K. J., Powers, S. K., Masuda, E. S., Taylor, V. C., Payan, D. G

  16. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction

    PubMed Central

    Smith, Ira J.; Godinez, Guillermo L.; Singh, Baljit K.; McCaughey, Kelly M.; Alcantara, Raniel R.; Gururaja, Tarikere; Ho, Melissa S.; Nguyen, Henry N.; Friera, Annabelle M.; White, Kathy A.; McLaughlin, John R.; Hansen, Derek; Romero, Jason M.; Baltgalvis, Kristen A.; Claypool, Mark D.; Li, Wei; Lang, Wayne; Yam, George C.; Gelman, Marina S.; Ding, Rongxian; Yung, Stephanie L.; Creger, Daniel P.; Chen, Yan; Singh, Rajinder; Smuder, Ashley J.; Wiggs, Michael P.; Kwon, Oh-Sung; Sollanek, Kurt J.; Powers, Scott K.; Masuda, Esteban S.; Taylor, Vanessa C.; Payan, Donald G.; Kinoshita, Taisei; Kinsella, Todd M.

    2014-01-01

    Controlled mechanical ventilation (CMV) is associated with the development of diaphragm atrophy and contractile dysfunction, and respiratory muscle weakness is thought to contribute significantly to delayed weaning of patients. Therefore, therapeutic strategies for preventing these processes may have clinical benefit. The aim of the current study was to investigate the role of the Janus kinase (JAK)/signal transducer and activator of transcription 3 (STAT3) signaling pathway in CMV-mediated diaphragm wasting and weakness in rats. CMV-induced diaphragm atrophy and contractile dysfunction coincided with marked increases in STAT3 phosphorylation on both tyrosine 705 (Tyr705) and serine 727 (Ser727). STAT3 activation was accompanied by its translocation into mitochondria within diaphragm muscle and mitochondrial dysfunction. Inhibition of JAK signaling during CMV prevented phosphorylation of both target sites on STAT3, eliminated the accumulation of phosphorylated STAT3 within the mitochondria, and reversed the pathologic alterations in mitochondrial function, reduced oxidative stress in the diaphragm, and maintained normal diaphragm contractility. In addition, JAK inhibition during CMV blunted the activation of key proteolytic pathways in the diaphragm, as well as diaphragm atrophy. These findings implicate JAK/STAT3 signaling in the development of diaphragm muscle atrophy and dysfunction during CMV and suggest that the delayed extubation times associated with CMV can be prevented by inhibition of Janus kinase signaling.—Smith, I. J., Godinez, G. L., Singh, B. K., McCaughey, K. M., Alcantara, R. R., Gururaja, T., Ho, M. S., Nguyen, H. N., Friera, A. M., White, K. A., McLaughlin, J. R., Hansen, D., Romero, J. M., Baltgalvis, K. A., Claypool, M. D., Li, W., Lang, W., Yam, G. C., Gelman, M. S., Ding, R., Yung, S. L., Creger, D. P., Chen, Y., Singh, R., Smuder, A. J., Wiggs, M. P., Kwon, O.-S., Sollanek, K. J., Powers, S. K., Masuda, E. S., Taylor, V. C., Payan, D. G

  17. Association of Dermatoglyphic Peculiarities with Dental Caries in Preschool Children of Lucknow, India

    PubMed Central

    Saha, Sabyasachi; Jagannath, GV; Singh, Sanjay; Saha, Sonali; Garg, Nishita

    2016-01-01

    ABSTRACT Background: Dermatoglyphics refers to study of the intricate dermal ridge configurations on the skin covering the palmar and plantar surfaces of hand and feet. The basis of considering dermatoglyphic patterns as genetic marker for dental caries is that the epithelium of finger buds as well as enamel has ectodermal origin, and both develop at the same time of intrauterine life. Aim: To assess the relationship between fingerprint patterns and dental caries among preschool children of Lucknow city. Study design: This study was of cross-sectional design. Materials and methods: The study group comprised 512 preschool children 2-6 years of age. The prevalence of caries was recorded using "Dentition status and treatment needs" (WHO basic oral health assessment form, 1997). They were divided into three groups as follows: Group I (dmft score = 0-2), group II (dmft score = 3-4) and group III (dmft score ≥5). The handprints of each child were taken using a stamp pad. The fingertip patterns were analyzed according to the classical method and were classified according to the topological method. The frequency of occurrence of type of dermatoglyphic pattern on fingertip of each digit was noted. Statistics: Chi-square test was used to test the significant difference in proportions. Means were compared using Student’s t-test and analysis of variance (ANOVA) or F-test. Results: Subjects belonging to groups II and III showed maximum occurrence of whorl pattern on all digits. Group I subjects had maximum occurrence of arch pattern. All the variables had statistically significant value, with a degree of divergence of specific dermatoglyphic patterns among all three groups. Conclusion: The dental caries susceptibility of an individual increased with incidence of whorl pattern and it decreased with incidence of arch pattern. How to cite this article: Singh E, Saha S, Jagannath GV, Singh S, Saha S, Garg N. Association of Dermatoglyphic Peculiarities with Dental Caries in

  18. Embedding loop quantum cosmology without piecewise linearity

    NASA Astrophysics Data System (ADS)

    Engle, Jonathan

    2013-04-01

    An important goal is to understand better the relation between full loop quantum gravity (LQG) and the simplified, reduced theory known as loop quantum cosmology (LQC), directly at the quantum level. Such a firmer understanding would increase confidence in the reduced theory as a tool for formulating predictions of the full theory, as well as permitting lessons from the reduced theory to guide further development in the full theory. This paper constructs an embedding of the usual state space of LQC into that of standard LQG, that is, LQG based on piecewise analytic paths. The embedding is well defined even prior to solving the diffeomorphism constraint, at no point is a graph fixed and at no point is the piecewise linear category used. This motivates for the first time a definition of operators in LQC corresponding to holonomies along non-piecewise linear paths, without changing the usual kinematics of LQC in any way. The new embedding intertwines all operators corresponding to such holonomies, and all elements in its image satisfy an operator equation which classically implies homogeneity and isotropy. The construction is made possible by a recent result proven by Fleischhack. Communicated by P Singh

  19. A Study of Correlation of Various Growth Indicators with Chronological Age

    PubMed Central

    Sandhu, Navreet; Puri, Taruna; Gulati, Ritika; Kashyap, Rita

    2015-01-01

    ABSTRACT Introduction: The aim of this study was to assess the relationship of chronological age with cervical vertebrae skeletal maturation, frontal sinus width and antegonial notch depth and a correlation, if any, among the three variables. Materials and methods: The samples were derived from lateral cephalometric radiographs of 80 subjects (40 males, 40 females; age range: 10 to 19 years). Cervical vertebral development was evaluated by the method of Hassel and Farman, frontal sinus width was measured by the method described by Ertürk and antegonial notch depth as described by Singer et al. The Pearson’s correlation coefficients were estimated to assess the relationship of chronological age with cervical vertebrae skeletal maturation, frontal sinus width and antegonial notch depth. Results: The Pearson’s correlation coefficient were 0.855 (p < 0.001) between chronological age and cervical vertebrae skeletal maturation, and 0.333 (p < 0.001) between chronological age and frontal sinus width. Conclusion: A highly significant positive correlation was found between chronological age and cervical vertebrae skeletal maturation, and between chronological age and frontal sinus width. Nonsignificant correlation was found between chronological age and antegonial notch depth. How to cite this article: Singh S, Sandhu N, Puri T, Gulati R, Kashyap R. A Study of Correlation of Various Growth Indicators with Chronological Age. Int J Clin Pediatr Dent 2015;8(3): 190-195. PMID:26628853

  20. Clinical relevance of radiologic examination of the skeleton and bone density measurements in osteoporosis of old age

    SciTech Connect

    Kuester, W.; Seidl, G.; Linkesch, W.; Kotscher, E.; Kovarik, J.; Willvonseder, R.; Kovarik, J.; Willvonseder, R.; Dorda, W.

    1981-10-01

    For the diagnosis of primary osteoporosis, various semiquantitative radiologic methods were compared in 149 unselected patients, aged over 50 years. Crush fracture syndrome (CFS), lumbar spine index (LSI), and Singh Index (SI) were assessed by three radiologists and after reevaluation, the intra- and interobserver errors were calculated. The reliability of the subjective grading was improved by joint and repeated reading of the radiographs. Additionally, the peripheral trabecular bone content was measured by photon absorption densitometry (PAD). To test the value of the various semiquantitative methods. LSI, Si, and PAD have been compared with sex-matching before and after separation into age in decades in CFS-positive and CFS-negative patients. In an attempt to differentiate osteoporotics and non-osteoporotics by CFS, our results indicate that CFS-positive and CFS-negative males cannot be separated by LSI, Si, and PAD, whereas in females these methods can discriminate irrespective of the age in decades. However, in age related groups, only SI can discriminate significantly between CFS-positive and CFS-negative females. Correlation of the semiquantitative methods, regardless of the diagnosis of a CFS, revealed a significant correlation-between SI and PAD, but no correlation between LSI and SI, and LSI and PAD, respectively.

  1. Effect of viscoelastic relaxation on moisture transport in foods. Part I: solution of general transport equation.

    PubMed

    Singh, Pawan P; Maier, Dirk E; Cushman, John H; Haghighi, Kamyar; Corvalan, Carlos

    2004-07-01

    Within the framework of continuum mechanics, Singh et al. developed an integro-differential equation, which applies to both Darcian (Fickian) and non-Darcian (non-Fickian) modes of fluid transport in swelling biological systems. A dimensionless form of the equation was obtained and transformed from moving Eulerian to the stationary Lagrangian coordinates. Here a solution scheme for the transport equation is developed to predict moisture transport and viscoelastic stresses in spheroidal biopolymeric materials. The equation was solved numerically and results used for predicting drying and sorption curves, moisture profiles, and viscoelastic stresses in soybeans. The Lagrangian solution was obtained by assembling together several schemes: the finite element method was used to discretize the equation in space; non-linearity was addressed using the Newton-Raphson method; the Volterra term was handled via a time integration scheme of Patlashenko et al. and the Galerkin rule was used to solve the time-differential term. The solution obtained in Lagrangian coordinates was transformed back to the Eulerian coordinates. In part II of this sequence we present the numerical results.

  2. Dependence of magnetic field and electronic transport of Mn4 Single-molecule magnet in a Single-Electron Transistor

    NASA Astrophysics Data System (ADS)

    Rodriguez, Alvar; Singh, Simranjeet; Haque, Firoze; Del Barco, Enrique; Nguyen, Tu; Christou, George

    2012-02-01

    Dependence of magnetic field and electronic transport of Mn4 Single-molecule magnet in a Single-Electron Transistor A. Rodriguez, S. Singh, F. Haque and E. del Barco Department of Physics, University of Central Florida, 4000 Central Florida Blvd., Orlando, Florida 32816 USA T. Nguyen and G. Christou Department of Chemistry, University of Florida, Gainesville, Florida 32611 USA Abstract We have performed single-electron transport measurements on a series of Mn-based low-nuclearity single-molecule magnets (SMM) observing Coulomb blockade. SMMs with well isolated and low ground spin states, i.e. S = 9/2 (Mn4) and S = 6 (Mn3) were chosen for these studies, such that the ground spin multiplet does not mix with levels of other excited spin states for the magnetic fields (H = 0-8 T) employed in the experiments. Different functionalization groups were employed to change the mechanical, geometrical and transport characteristics of the molecules when deposited from liquid solution on the transistors. Electromigration-broken three-terminal single-electron transistors were used. Results obtained at temperatures down to 240 mK and in the presence of high magnetic fields will be shown.

  3. Mixed fluvial systems of Messak Sandstone, a deposit of Nubian lithofacies, southwestern Libya

    SciTech Connect

    Lorenz, J.C.

    1987-05-01

    The Messak Sandstone is a coarse to pebbly, tabular cross-bedded, Lower Cretaceous deposit of the widespread Nubian lithofacies. It was deposited at the northern edge of the Murzuq basin in southwestern Libya. Although the sedimentary record is predominantly one of braided fluvial systems, a common subfacies within the formation is interpreted to record the passage of straight-crested sand waves across laterally migrating point bars in sinuous rivers, similar to the pattern documented by Singh and Kumar on the modern Ganga and Yamuna Rivers. Because the sand waves were larger on the lower parts of the point bars, lateral migration created diagnostic thinning-upward, unidirectional cosets of tabular cross-beds as well as fining-upward, grain-size trends. Common, thick, interbedded claystones, deposited in associated paludal and lacustrine environments, and high variance in cross-bed dispersion patterns also suggest the local presence of sinuous fluvial systems within the overall braided regime. The Messak Sandstone contains some of the features that led Harms et al to propose an unconventional low-sinuosity fluvial environment for the Nubian lithofacies in Egypt, and the continuously high water levels of this model may explain channel-scale clay drapes and overturned cross-beds in the Messak. However, most of the Messak characteristics are incompatible with the low-sinuosity model, suggesting instead that the fluvial channels in the Murzuq basin alternated between braided and high-sinuosity patterns.

  4. Cyclic electron flow around photosystem I is enhanced at low pH.

    PubMed

    Tongra, Teena; Bharti, Sudhakar; Jajoo, Anjana

    2014-10-01

    Earlier studies have shown that at low pH (pH 5.5), PS II fluorescence decreases with concomitant increase in PS I fluorescence (Singh-Rawal et al., 2010). In order to shed light on the reasons of the above stated change, spinach leaf discs were treated with buffers of different pH (7.5, 6.5 and 5.5)and decrease in the photochemical quantum yield of PS II,Y(II) and increase in the photochemical quantum yield of PS I,Y(I) was observed. We observed an enhanced protection against over-reduction of PS I acceptor side at low pH (5.5) treated leaves. This was obviously achieved by the rapid build-up of trans-thylakoid pH gradient at low light intensities and was directly associated with a steep increase in non- photochemical quenching of chlorophyll fluorescence and a decrease in the electron transport rate of PS II. Our results suggested a strong stimulation of cyclic electron flow around PS I at pH 5.5 which directly supports protection against over-reduction of the PS I acceptor side.

  5. Classical nucleation theory of microstructure development under cascade-damage irradiation

    NASA Astrophysics Data System (ADS)

    Semenov, A. A.; Woo, C. H.

    2003-12-01

    Cascade irradiation produces a significant fraction of the damage in the form of small mobile and immobile vacancy and interstitial clusters. This has led to the introduction of the Woo-Singh production bias theory. In the pursuant studies, the predominant effort that has been spent is in investigating the validity of the concept, and in its usefulness in complementing the traditional theory based on the concept of sink bias. Although plenty of theoretical and experimental results supports the concept, relatively little attention has been paid to the important area of microstructure nucleation. Within the framework of the classical theory of nucleation of overcritical precipitates from small subcritical nuclei, the nucleation processes at elevated temperatures of both voids and interstitial loops from the primary clusters are similar, and can be similarly treated. Recognizing the importance of stochastic fluctuations in the evolution of small embryos, a single-component nucleation theory is formulated using the Fokker-Planck equation, to take into account the stochastic effects of the fluxes of mobile defects, arising from the random nature of diffusion jumps and cascade initiation. Analytic solutions for the separate cases of voids and Frank loops are obtained, and the corresponding effects on the evolution of the microstructure are discussed.

  6. Possible Angular Momentum Dependence of Dissipation in Nuclear Fission

    NASA Astrophysics Data System (ADS)

    Ye, Wei; Toke, Jan; Udo Schroeder, W.

    2008-04-01

    A comparative analysis of the pre-scission neutron multiplicities observed in a new experiment [1] and one reported earlier [2] suggests that, besides known deformation [3] and temperature [4] dependencies, nuclear dissipation in fission may have an angular momentum dependence. The analysis based on a Langevin equation coupled with a statistical decay model [3] considers angular momentum effects on fission dynamics. Pre-saddle reduced dissipation coefficients of β = 2 x10^21s-1 and 3 x10^21s-1 have been extracted for the matched reactions ^16O + ^181Ta and ^19F + ^178Hf [1],respectively. The difference in the extracted β values is attributed to the difference in the angular momenta contributing to the fission process in the two reactions. Work attempting to derive a quantitative expression for an angular momentum dependence of the dissipation strength is in progress. [1] H.Singh et al., Phys. Rev. C76 (2007) 044610 [2] L.G.Moretto et al., Phys. Rev. Lett. 75 (1995) 4186; Phys. Rev. C54 (1996) 3062 [3] P.Frobrich and I.I.Gontchar, Phys. Rep. 292(1998) 131 [4] P.Paul and M.Thoennessen, Ann. Rev. Part. Sci. 44(1994) 65

  7. Comparative Evaluation of Shear Bond Strength of Various Glass Ionomer Cements to Dentin of Primary Teeth: An in vitro Study

    PubMed Central

    Jaidka, Shipra; Singh, Deepti J; Sibal, Gurleen K

    2016-01-01

    Aim To evaluate and compare shear bond strength of various glass ionomer cements (GICs) to dentin of primary teeth. Materials and methods Sample size taken for the study was 72 deciduous molars with intact buccal or lingual surfaces. Samples were randomly divided into three groups, i.e., groups A, B, and C and were restored with conventional type II GIC, type II light cure (LC) GIC, and type IX GIC respectively. Thermocycling was done to simulate oral conditions. After 24 hours, shear bond strength was determined using Instron Universal testing Machine at crosshead speed of 0.5 mm/ minute until fracture. Results were tabulated and statistically analyzed. Results It was found that the shear bond strength was highest in group B (LC GIC) 9.851 ± 1.620 MPa, followed by group C (type IX GIC) 7.226 ± 0.877 MPa, and was lowest in group A (conventional GIC) 4.931 ± 0.9735 MPa. Conclusion Light cure GIC was significantly better than type IX GIC and conventional GIC in terms of shear bond strength. How to cite this article Somani R, Jaidka S, Singh DJ, Sibal GK. Comparative Evaluation of Shear Bond Strength of Various Glass Ionomer Cements to Dentin of Primary Teeth: An in vitro Study. Int J Clin Pediatr Dent 2016;9(3):192-196. PMID:27843248

  8. Drought modeling - A review

    NASA Astrophysics Data System (ADS)

    Mishra, Ashok K.; Singh, Vijay P.

    2011-06-01

    SummaryIn recent years droughts have been occurring frequently, and their impacts are being aggravated by the rise in water demand and the variability in hydro-meteorological variables due to climate change. As a result, drought hydrology has been receiving much attention. A variety of concepts have been applied to modeling droughts, ranging from simplistic approaches to more complex models. It is important to understand different modeling approaches as well as their advantages and limitations. This paper, supplementing the previous paper ( Mishra and Singh, 2010) where different concepts of droughts were highlighted, reviews different methodologies used for drought modeling, which include drought forecasting, probability based modeling, spatio-temporal analysis, use of Global Climate Models (GCMs) for drought scenarios, land data assimilation systems for drought modeling, and drought planning. It is found that there have been significant improvements in modeling droughts over the past three decades. Hybrid models, incorporating large scale climate indices, seem to be promising for long lead-time drought forecasting. Further research is needed to understand the spatio-temporal complexity of droughts under climate change due to changes in spatio-temporal variability of precipitation. Applications of copula based models for multivariate drought characterization seem to be promising for better drought characterization. Research on decision support systems should be advanced for issuing warnings, assessing risk, and taking precautionary measures, and the effective ways for the flow of information from decision makers to users need to be developed. Finally, some remarks are made regarding the future outlook for drought research.

  9. Tracking and Monitoring Oil Slicks Using remote Sensing

    NASA Astrophysics Data System (ADS)

    Klemas, V. V.

    2011-12-01

    Tracking and Monitoring Oil Slicks Using Remote Sensing Victor Klemas, Ph.D. , College of Earth, Ocean and Environment, University of Delaware, Newark, DE 19716 Abstract Oil spills can harm marine life in the ocean, estuaries and wetlands. To limit the damage by a spill and facilitate cleanup efforts, emergency managers need information on spill location, size and extent, direction and speed of oil movement, wind, current, and wave information for predicting oil drift and dispersion. The main operational data requirements are fast turn-around time and frequent imaging to monitor the dynamics of the spill. Radar and multispectral remote sensors on satellites and aircraft meet most of these requirements by tracking the spilled oil at various resolutions, over wide areas and at frequent intervals. They also provide key inputs to drift prediction models and facilitate targeting of skimming and booming efforts. Satellite data are frequently supplemented by information provided by aircraft, ships and remotely controlled underwater robots. The Sea Princess tanker grounding off the coast of Wales and the explosion on the Deepwater Horizon rig in the Gulf of Mexico provide two representative, yet different, scenarios for evaluating the effectiveness of remote sensors during oil spill emergencies. Session NH17: Remote Sensing of Natural Hazards Session Chair: Ramesh P. Singh Sponsor: Natural Hazards (NH)

  10. A molecular model for the active site of S-adenosyl- l-homocysteine hydrolase

    NASA Astrophysics Data System (ADS)

    Yeh, Jerry C.; Borchardt, Ronald T.; Vedani, Angelo

    1991-06-01

    S-adenosyl- l-homocysteine hydrolase (AdoHcy hydrolase, EC 3.3.1.1.), a specific target for antiviral drug design, catalyzes the hydrolysis of AdoHcy to adenosine (Ado) and homocysteine (Hcy) as well as the synthesis of AdoHcy from Ado and Hcy. The enzyme isolated from different sources has been shown to contain tightly bound NAD+. Based on the 2.0 Å-resolution X-ray crystal structure of dogfish lactate dehydrogenase (LDH), which is functionally homologous to AdoHcy hydrolase, and the primary sequence of rat liver AdoHcy hydrolase, we have derived a molecular model of an extended active site for AdoHcy hydrolase. The computational mutation was performed using the software MUTAR (Yeh et al., University of Kansas, Lawrence), followed by molecular mechanics optimizations using the programs AMBER (Singh et al., University of California, San Francisco) and YETI (Vedani, University of Kansas). Solvation of the model structure was achieved by use of the program SOLVGEN (Jacober, University of Kansas); 56 water molecules were explicitly included in all refinements. Some of these may be involved in the catalytic reaction. We also studied a model of the complex of AdoHcy hydrolase with NAD+, as well as the ternary complexes of the redox reaction catalyzed by AdoHcy hydrolase and has been used to differentiate the relative binding strength of inhibitors.

  11. Bis[(1S)-1 4-azanediyl-1-(9-deazaadenin-9-yl)-1 4-dideoxy-5-methylsulfanyl-D-ribitol] tetrakis(hydrochloride) monohydrate: structure DFT energy and ligand docking results of a potent methylthioadenosine phosphorylase inhibitor found in different

    SciTech Connect

    G Gainsford; G Evans; K Johnston; M Seth

    2011-12-31

    The title compound, abbreviated as 5'ThiomethylImmA, is a potent inhibitor of methylthioadenosine phosphorylase [Singh et al. (2004). Biochemistry, 43, 9-18]. The synchrotron study reported here shows that the hydrochloride salt crystallizes with two independent, nearly superimposable, dications as a monohydrate with formula 2C{sub 12}H{sub 19}N{sub 5}O{sub 2}S{sup 2+}{center_dot}4Cl{sup -}{center_dot}H{sub 2}O. Hydrogen bonding utilizing the H atoms of the dication is found to favor certain molecular conformations in the salt, which are significantly different from those found as bound in the enzyme. Ligand docking studies starting from either of these dications or related neutral structures successfully place the conformationally revised structures in the enzyme active site but only under particular hydrogen-bonding and molecular flexibility criteria. Density functional theory calculations verify the energy similarity of the indendent cations and confirm the significant energy cost of the required conformation change to the enzyme bound form. The results suggest the using crystallographically determined free ligand coordinates as starting parameters for modelling may have serious limitations.

  12. Biofilm Formation by Drug Resistant Enterococci Isolates Obtained from Chronic Periodontitis Patients

    PubMed Central

    Mehta, Manjula; Sood, Shaveta; Sharma, Jyoti

    2017-01-01

    Introduction Enterococci are an important cause of opportunistic nosocomial infections and several multidrug resistant strains have emerged. The severity of periodontal diseases is managed by reduction in the pathogenic bacteria. There is a need to assess the prevalence and antibiotic susceptibility of enterococci colonizing the periodontal pocket and correlate its biofilm formation ability because oral biofilms provide a protective environment and are a reservoir of bacterial colonization of the gingival crevice. Aim To investigate possible association between antibiotic susceptibility and biofilm formation in enterococci isolates from chronic periodontitis patients. Materials and Methods This retrospective study was conducted at Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Punjab University, Chandigarh from January 2015 to October 2015. Sterile paper points were inserted in the periodontal pocket of 100 subjects and put in a transport media. Forty -six isolates were identified as enterococci. The isolates were further examined for their ability to form biofilm by microtitre plate assay and antimicrobial susceptibility testing was done by disc diffusion method for clinically relevant antibiotics. Results Significant relationship (p<0.001) was found between biofilm production with antibiotic resistance to Vancomycin, Erythromycin, Ciprofloxacin, Tiecoplanin, Amoxycillin and Gentamycin. Conclusion The study demonstrates a high propensity among the isolates of Enterococci to form biofilm and a significant association of biofilm with multiple drug resistance. PMID:28273964

  13. Genetic Circuit Architectures Underlying Cell Fate Choices for Immunity

    NASA Astrophysics Data System (ADS)

    Dinner, Aaron

    2009-03-01

    Antigen stimulated B cells follow an unusual developmental trajectory that transiently passes through a germinal center state, which promotes receptor affinity maturation and immunoglobulin class switching, before terminally differentiating into antibody secreting plasma cells. It was found that graded expression of the transcription factor IRF-4 regulates cell fate, but the relationship between antigen receptor signaling, the network of interactions with IRF-4, and cell fate was not known. This talk describes models that link ligand-receptor avidity with cell fate. The models have been validated experimentally by directly varying the levels and kinetics of IRF-4 accumulation. Furthermore, signaling through the antigen receptor is demonstrated to control the expression of IRF-4 and in turn the frequency of B cells that undergo class switching before differentiating into plasma cells. These findings provide an explanation for experiments that measure B cell numbers in transgenic mice. The architecture of our regulatory circuit provides a general mechanism for quantitative variations in a signal to be translated into a binary cell-fate choice involving transient expression of one of the two developmental fates. In collaboration with Aryeh Warmflash, Ying Li, Roger Sciammas, and Harinder Singh, The University of Chicago.

  14. Self-reported defence mechanisms as an outcome measure in psychotherapy: a study on the German version of the Defence Style Questionnaire DSQ 40.

    PubMed

    Schauenburg, Henning; Willenborg, Verena; Sammet, Isa; Ehrenthal, Johannes C

    2007-09-01

    The psychoanalytically informed construct of 'defence mechanisms' is of central importance for the understanding of the dynamics of inner conflicts and the onset of neurotic symptoms. Objective and valid assessment of 'defence' is difficult. There are a number of observer rating instruments but only few self-report questionnaires. The German version of the 'Defence Style Questionnaire - DSQ 40' (Andrews, Singh, & Bond, 1993) was examined with regard to its factorial and content validity, and its sensitivity to change during inpatient psychotherapy. One hundred and fifty-five patients with mixed diagnoses were administered the DSQ 40 and the SCL-90-R before and after 3 months of inpatient psychotherapy. Diagnoses were mostly affective and anxiety disorders as well as eating disorders, and there was a high comorbidity of personality disorders. After deletion of some items due to insufficient pairwise item-intercorrelation or false classification to a defence mechanism by experienced clinicians, we found three stable factors of defence (maladaptive, intermediate-neurotic and adaptive) consistent with the previous research. After 3 months of therapy, a decrease in maladaptive mechanisms and an increase in adaptive patterns were found, while neurotic mechanisms did not change on average. Our shortened version of the DSQ 40 was shown to be a valid instrument for the assessment of defence mechanisms and change in these mechanisms after psychotherapy. Our design did not permit an assessment of whether or not the change in defence mechanisms was due to the therapeutic treatment.

  15. RNA-protein cross-links induced by sensitization with a pyrroloquinolinone derivative, a furocoumarin analogue.

    PubMed

    Baccichetti, F; Marzano, C; Carlassare, F; Guiotto, A; Bordin, F

    1997-10-01

    The capacity of 2,6-dimethyl-9-methoxy-4H-pyrrolo [3,2,1-ij] quinolin-4-one (PQ), a furocoumarin analogue, of inhibiting protein synthesis in Ehrlich cells upon UVA irradiation was investigated. Using 8-methoxypsoralen (8-MOP) as a reference, we observed that in our short-term test the block of RNA synthesis do not affect protein synthesis, which is driven by pre-synthesised molecules of m-RNA; actually 8-MOP, studied at 100 microM concentration, practically abolished RNA synthesis without affecting significantly protein synthesis. Studying PQ sensitization in HL60 cells by alkaline elution and protein precipitation, the formation of covalent RNA-protein cross-links was observed. 8-MOP, assayed in severe experimental conditions, induced only moderate amounts of such lesion. On the basis of the data obtained in experiments carried out using various scavengers or exposing cells to UVA light in a nitrogen atmosphere, this damage appeared to be due to singlet oxygen formation, which is generated by PQ to a large extent. These results are consistent with the data obtained by H. Singh and J.A. Vadasz (Singlet oxygen: a major reactive species in the furocoumarin photosensitized inactivation of E.coli ribosomes, Photochem. Photobiol., 28 (1978) 539-545) on E.coli ribosomes. The lower activity we observed with 8-MOP might be attributed to a different sensitivity of whole mammalian cells in comparison with isolated ribosomes.

  16. Cognitive Advantages of Blending with Material Anchors in Energy Instruction

    NASA Astrophysics Data System (ADS)

    Close, Hunter; Close, Eleanor; Scherr, Rachel; McKagan, Sarah

    2012-03-01

    Conceptual blending theory [1] explains how the human imagination creates unreal situations that help us think about reality. In these imaginary blended situations, we establish new correspondences, interactions, and dynamics, and the outcomes of the dynamics lend insight to the nature of various real situations that were used to compose the blend. Blends are not just in the head, however; in some cases, a material system participates in the blend by lending its material structure as conceptual structure [2]. In the instructional activity Energy Theater [3], people represent units of energy and move around in order to solve puzzles of energy transfer and transformation. We use the ideas of blending and material anchors to understand how learners are able to use the representation to their cognitive advantage. [4pt] [1] Fauconnier, G. & Turner, M. (2002). The Way We Think: Conceptual Blending and the Mind's Hidden Complexities. New York: Basic Books.[0pt] [2] Hutchins, E. (2005) Material anchors for conceptual blends. Journal of Pragmatics 37, 1555-1577.[0pt] [3] Scherr, R. E., Close, H. G., McKagan, S. B., & Close, E. W. (2010) ``Energy Theater'': Using the body symbolically to understand energy. In C. Singh, M. Sabella, & S. Rebello (Eds.) 2010 PERC Proceedings. Melville, NY: AIP Press.

  17. Effect of partial atomic charges on the calculated free energy of solvation of poly(vinyl alcohol) in selected solvents.

    PubMed

    Noorjahan, Abolfazl; Choi, Phillip

    2015-03-01

    It is well-known that properties of poly(vinyl alcohol) (PVA) in the pure and solution states depend largely on the hydrogen bonding networks formed. In the context of molecular simulation, such networks are handled through the Coulombic interactions. Therefore, a good set of partial atom charges (PACs) for simulations involving PVA is highly desirable. In this work, we calculated the PACs for PVA using a few commonly used population analysis schemes with a hope to identify an accurate set of PACs for PVA monomers. To evaluate the quality of the calculated parameters, we have benchmarked their predictions for free energy of solvation (FES) in selected solvents by molecular dynamics simulations against the ab initio calculated values. Selected solvents were water, ethanol and benzene as they covered a range of size and polarity. Also, PVA with different tacticities were used to capture their effect on the calculated FESs. Based on our results, neither PACs nor FESs are affected by the chain tacticity. While PACs predicted by the Merz-Singh-Kollman scheme were close to original values in the OPLS-AA force field in way that no significant difference in properties of pure PVA was observed, free energy of solvation calculated using such PACs showed greater agreement with ab initio calculated values than those calculated by OPLS-AA (and all other schemes used in this work) in all three solvents considered.

  18. Cavity optomechanics -- beyond the ground state

    NASA Astrophysics Data System (ADS)

    Meystre, Pierre

    2011-05-01

    The coupling of coherent optical systems to micromechanical devices, combined with breakthroughs in nanofabrication and in ultracold science, has opened up the exciting new field of cavity optomechanics. Cooling of the vibrational motion of a broad range on oscillating cantilevers and mirrors near their ground state has been demonstrated, and the ground state of at least one such system has now been reached. Cavity optomechanics offers much promise in addressing fundamental physics questions and in applications such as the detection of feeble forces and fields, or the coherent control of AMO systems and of nanoscale electromechanical devices. However, these applications require taking cavity optomechanics ``beyond the ground state.'' This includes the generation and detection of squeezed and other non-classical states, the transfer of squeezing between electromagnetic fields and motional quadratures, and the development of measurement schemes for the characterization of nanomechanical structures. The talk will present recent ``beyond ground state'' developments in cavity optomechanics. We will show how the magnetic coupling between a mechanical membrane and a BEC - or between a mechanical tuning fork and a nanoscale cantilever - permits to control and monitor the center-of-mass position of the mechanical system, and will comment on the measurement back-action on the membrane motion. We will also discuss of state transfer between optical and microwave fields and micromechanical devices. Work done in collaboration with Dan Goldbaum, Greg Phelps, Keith Schwab, Swati Singh, Steve Steinke, Mehmet Tesgin, and Mukund Vengallatore and supported by ARO, DARPA, NSF, and ONR.

  19. Field dependent ordering temperature in copper pyrazine perchlorate, Cu(pz)2(ClO4)2

    NASA Astrophysics Data System (ADS)

    Landee, Christopher; Xiao, Fan; Turnbull, Mark; Tsyrulin, N.; Kenzelmann, Michel; van Tol, Hans

    2007-03-01

    Copper pyrazine perchlorate is a molecular-based 2D S=1/2 Heisenberg antiferromagnet (QHAF) with a moderate exchange constant (J/k = 17.5 K) and a saturation field of 60 T. The zero-field ordering temperature, as recently determined by muon spin relaxation experiments [1], is 4.3 K corresponding to excellent isolation (J'/J 8x10-4) between magnetic layers [2]. Recent studies of Cu(pz)2(ClO4)2 in applied fields (specific heat and ESR) show the ordering transition to increase with field by as much as 30% in a field of nine tesla. This effect will be discussed in terms of a field-induced anisotropy crossover model [3]. 1. T. Lancaster, S. J. Blundell et al, submitted for publication. 2. P. Sengupta, A. W. Sandvik, and R. R. P. Singh, Phys. Rev. B 68, 094423 (2003). 3. A. Cuccoli et al, Phys. Rev. B 68, 060402 (2003).

  20. A Palaeohydrological Shift during Neogene East Antarctic Ice Sheet Retreat

    NASA Astrophysics Data System (ADS)

    Rees-Owen, R. L.; Newton, R.; Ivanovic, R. F.; Francis, J.; Tindall, J. C.; Riding, J. B.

    2015-12-01

    The East Antarctic Ice Sheet is an important driver of global climate, playing a particular role in governing albedo and atmospheric circulation (eg. Singh et al., 2013). Recent evidence from marine sediment and terrestrial glaciovolcanic sequences suggests that the EAIS underwent periodic retreat and collapse in response to warmer climates during the late Neogene (14 to 3 million years ago). Mummified prostrate trees recovered from palaeosols at Oliver Bluffs in the Beardmore Glacier region, Transantarctic Mountains (85° S), represent a rare insight into the terrestrial palaeoclimate during one of these periods of retreat. Prostrate trees are an understudied but useful tool for interrogating endmember (e.g. periglacial) environments at high altitudes and latitudes. We present exciting new palaeoclimate data from the sequence at Oliver Bluffs. δ18O analysis of tree ring cellulose suggests that Antarctic summer palaeoprecipitation was enriched relative to today (-25 to -5‰ for ancient, -35 to -20‰ for modern); consistent with our isotope-enabled general circulation model simulations. The MBT/CBT palaeothermometer gives a summer temperature of 3-6ºC, consistent with other palaeobotanical climate indices. These geological and model data have wide-ranging implications for our understanding of the hydrological cycle during this time period. We present data suggesting that changes in moisture recycling and source region indicate a markedly different hydrological cycle.

  1. Effect of household processing on fenazaquin residues in okra fruits.

    PubMed

    Duhan, Anil; Kumari, Beena; Gulati, Rachna

    2010-02-01

    Fenazaquin (4-[[4 (1,1-dimethylethyl) phenyl] ethoxy]quinazoline) is a new acaricide of the quinazoline class. Residue levels of fenazaquin were determined in unprocessed and processed okra fruits to evaluate the effect of different processes (washing, boiling and washing followed by boiling) in reduction of residues of this pesticide in okra. The study was carried out on okra crop (Variety, Varsha Uphar) in research farm of Chaudhary Charan Singh Haryana Agricultural University, Hisar with application of fenazaquin (Magister 10 EC) @ 125 ga.i./ha (Single Dose, T(1)) and 250 g a.i./ha (Double Dose, T(2)). Samples of okra fruits were collected on 0, 3, 7, 15 days after treatment and at harvest (30 days). Residues were estimated by gas chromatograph equipped with capillary column and nitrogen phosphorus detector. Residues reached below maximum residue limit of 0.01 mg/kg at harvest. The residues dissipated with half-life period of 3.13 days at lower dose and 4.43 days at higher dose. Processing is shown to be very effective in reducing the levels of fenazaquin residues in okra fruits. Maximum reduction (60-61%) was observed by washing + boiling followed by boiling/cooking (38-40%) and then by washing (31-32%).

  2. Persistence and effect of processing on reduction of chlorpyriphos residues in okra fruits.

    PubMed

    Samriti; Chauhan, Reena; Kumari, Beena

    2011-08-01

    Residue levels of chlorpyriphos were determined in unprocessed and processed okra fruits to evaluate the effect of different processes (washing and washing followed by boiling/cooking) on reduction of residues of this pesticide in okra. The study was carried out on okra crop (Variety, Varsha Uphar) in research farm of Chaudhary Charan Singh, Haryana Agricultural University, Hisar with application of chlorpyriphos (Radar 20 EC) at 200 g a.i./ha and 400g a.i./ha (Single Dose, T(1)) and 400 g a.i./ha (Double Dose, T(2)). Samples of okra fruits were collected on 0, 1, 3, 5, 7, 10, 15 days and at harvest after treatment. Residues were estimated by GC-ECD system and reached BDL of 0.010 mg kg(-1) on 7th and 15th day in case of single and double dose, respectively. The residues dissipated with half-life period of 3.15 days at lower dose and 3.46 days at higher dose following biphasic first order kinetics. Processing was found very effective in reducing the levels of chlorpyriphos residues in okra fruits. Maximum reduction (64-77%) was observed by washing + boiling followed by washing (13-35%).

  3. Biodynamic performance of hyaluronic acid versus synovial fluid of the knee in osteoarthritis.

    PubMed

    Corvelli, Michael; Che, Bernadette; Saeui, Christopher; Singh, Anirudha; Elisseeff, Jennifer

    2015-08-01

    Hyaluronic acid (HA), a natural biomaterial present in healthy joints but depleted in osteoarthritis (OA), has been employed clinically to provide symptomatic relief of joint pain. Joint movement combined with a reduced joint lubrication in osteoarthritic knees can result in increased wear and tear, chondrocyte apoptosis, and inflammation, leading to cascading cartilage deterioration. Therefore, development of an appropriate cartilage model that can be evaluated for its friction properties with potential lubricants in different conditions is necessary, which can closely resemble a mechanically induced OA cartilage. Additionally, a comparison of different models with and without endogenous lubricating surface zone proteins, such as PRG4 promotes a well-rounded understanding of cartilage lubrication. In this study, we present our findings on the lubricating effects of HA on different articular cartilage model surfaces in comparison to synovial fluid, a physiological lubricating biomaterial. The mechanical testings data demonstrated that HA reduced average static and kinetic friction coefficient values of the cartilage samples by 75% and 70%, respectively. Furthermore, HA mimicked the friction characteristics of freshly harvested natural synovial fluid throughout all tested and modeled OA conditions with no statistically significant difference. These characteristics led us to exclusively identify HA as an effective boundary layer lubricant in the technology that we develop to treat OA (Singh et al., 2014).

  4. Common genetic influences on negative emotionality and a general psychopathology factor in childhood and adolescence.

    PubMed

    Tackett, Jennifer L; Lahey, Benjamin B; van Hulle, Carol; Waldman, Irwin; Krueger, Robert F; Rathouz, Paul J

    2013-11-01

    Previous research using confirmatory factor analysis to model psychopathology comorbidity has supported the hypothesis of a broad general factor (i.e., a "bifactor"; Holzinger & Swineford, 1937) of psychopathology in children, adolescents, and adults, with more specific higher order internalizing and externalizing factors reflecting additional shared variance in symptoms (Lahey et al., 2012; Lahey, van Hulle, Singh, Waldman, & Rathouz, 2011). The psychological nature of this general factor has not been explored, however. The current study tested a prediction, derived from the spectrum hypothesis of personality and psychopathology, that variance in a general psychopathology bifactor overlaps substantially-at both phenotypic and genetic levels-with the dispositional trait of negative emotionality. Data on psychopathology symptoms and dispositional traits were collected from both parents and youth in a representative sample of 1,569 twin pairs (ages 9-17 years) from Tennessee. Predictions based on the spectrum hypothesis were supported, with variance in negative emotionality and the general factor overlapping substantially at both phenotypic and etiologic levels. Furthermore, stronger correlations were found between negative emotionality and the general psychopathology factor than among other dispositions and other psychopathology factors.

  5. Optimizing available phosphorus in calcareous soils fertilized with diammonium phosphate and phosphoric acid using Freundlich adsorption isotherm.

    PubMed

    Naeem, Asif; Akhtar, Muhammad; Ahmad, Waqar

    2013-01-01

    In calcareous soils, phosphorus (P) retention and immobilization take place due to precipitation and adsorption. Since soil pH is considered a major soil variable affecting the P sorption, an acidic P fertilizer could result in low P adsorption compared to alkaline one. Therefore, P adsorption from DAP and phosphoric acid (PA) required to produce desired soil solution P concentration was estimated using Freundlich sorption isotherms. Two soils from Faisalabad and T. T. Singh districts were spiked with 0, 10, and 20 % CaCO3 for 15 days. Freundlich adsorption isotherms (P = aC(b/a)) were constructed, and theoretical doses of PA and DAP to develop a desired soil solution P level (i.e., 0.20 mg L(-1)) were calculated. It was observed that P adsorption in soil increased with CaCO3. Moreover, at all the levels of CaCO3, P adsorption from PA was lower compared to that from DAP in both the soils. Consequently, lesser quantity of PA was required to produce desired solution P, 0.2 mg L(-1), compared to DAP. However, extrapolating the developed relationship between soil CaCO3 contents and quantity of fertilizer to other similar textured soils needs confirmation.

  6. Triplet proximity effect in superconducting heterostructures with a half-metallic layer

    NASA Astrophysics Data System (ADS)

    Mironov, S.; Buzdin, A.

    2015-11-01

    We present the Usadel theory describing the superconducting proximity effect in heterostructures with a half-metallic layer. It is shown that the full spin polarization inside the half-metals gives rise to an additional component of the Green's function which results in the giant triplet spin-valve effect in superconductor (S)-ferromagnet (F)-half-metal (HM) trilayers and provides a natural explanation for the φ0-junction formation in the S/F/HM/F/S systems. In addition, we consider the exactly solvable model of the S/F/HM trilayers of atomic thickness and demonstrate that it reproduces the main features of the spin-valve effect found within the Usadel approach. Our results are shown to be in qualitative agreement with the recent experimental data on the spin-valve effect in MoGe /Ni /Cu /CrO2 hybrids [Singh et al., Phys. Rev. X 5, 021019 (2015), 10.1103/PhysRevX.5.021019].

  7. A measure of scale-dependent asymmetry in turbulent boundary layer flows

    NASA Astrophysics Data System (ADS)

    Guala, Michele; Singh, Arvind

    2015-11-01

    The distribution of scale-dependent, streamwise velocity increments is investigated in turbulent boundary layer flows at laboratory and atmospheric Reynolds number, using the SAFL wind tunnel (Singh et al. Phys. of Fluids 2014) and the SLTEST data (Metzger et al. Phil. Trans Royal Soc. A 2007). The third order moments of velocity increments, or asymmetry index As(a,z), is computed for varying wall distance z and scale separation a, where it was observed to leave a robust, distinct signature in the form of a hump, independent of Reynolds number and located across the inertial subrange. The hump is observed for z + <5000, with a tendency to increase in amplitude, and shift towards smaller timescales, as the wall is approached. Comparing the two datasets, the hump vertical location, obeying to inner wall scaling, is regarded to as a genuine feature of the canonical turbulent boundary layer. The magnitude cumulant analysis of the scale-dependent velocity increments indicates that intermittency is also enhanced in the same flow region. The combination of asymmetry and intermittency is inferred to point at non-local energy transfer across a range of scales and may thus be used to quantify interactions between structural types in boundary layer flows.

  8. Adiabatic channel capture theory applied to cold atom-molecule reactions: Li + CaH \\to LiH + Ca at 1K

    NASA Astrophysics Data System (ADS)

    Tscherbul, Timur V.; Buchachenko, Alexei A.

    2015-03-01

    We use quantum and classical adiabatic capture theories to study the chemical reaction Li + CaH \\to LiH + Ca. Using a recently developed ab initio potential energy surface, which provides an accurate representation of long-range interactions in the entrance reaction channel, we calculate the adiabatic channel potentials by diagonalizing the Li-CaH Hamiltonian as a function of the atom-molecule separation. The resulting adiabatic channel potentials are used to calculate both the classical and quantum capture probabilities as a function of collision energy, as well as the temperature dependencies of the partial and total reaction rates. The calculated reaction rate agrees well with the measured value at 1 K (V Singh et al 2012 Phys. Rev. Lett. 108 203201), suggesting that the title reaction proceeds without an activation barrier. The calculated classical adiabatic capture rate agrees well with the quantum result in the multiple-partial-wave regime of relevance to the experiment. Significant differences are found only in the ultracold limit (T\\lt 1 mK), demonstrating that adiabatic capture theories can predict the reaction rates with nearly quantitative accuracy in the multiple-partial-wave regime.

  9. 23 Na and 17O NMR studies of hyperkagome Na4Ir3O8

    NASA Astrophysics Data System (ADS)

    Shockley, Abigail; Bert, Fabrice; Orain, Jean-Christophe; Okamoto, Yoshihiko; Mendels, Philippe

    2015-03-01

    Na4Ir3O8 is a unique case of a 3D corner sharing triangular lattice which can be decorated with quantum spins. It has spurred a lot of theoretical interest as a spin liquid candidate of a new kind where the Hamiltonian might not be thought in terms of a simple Heisenberg case because of spin orbit coupling on the Ir 5d element. We present a comprehensive set of NMR data taken on both the 23Na and 17O sites. We have found that magnetic freezing of all Ir sites sets in below Tf ~ 7.5K ~ 0 . 019 J with a clear hyperfine field transferred from Ir moments and a drastic decrease of 1 /T1 . Above Tf, physical properties are expected to be a landmark of frustration in this exotic geometry. We will discuss our shift and relaxation data in the temperature range of 300K to 7.5 K in the light of published thermodynamic measurements (Y. Okamotoa et al, PRL 99 137207, 2007 and Y. Singh et al, PRB 88 220413(R), 2013) and comment on their implications for the already existing large body of theoretical work.

  10. Nonlinear instability and intermittent nature of magnetic reconnection in solar chromosphere

    NASA Astrophysics Data System (ADS)

    Singh, K. A. P.; Hillier, Andrew; Isobe, Hiroaki; Shibata, Kazunari

    2015-10-01

    The recent observations of Singh et al. (2012, ApJ, 759, 33) have shown multiple plasma ejections and the intermittent nature of magnetic reconnection in the solar chromosphere, highlighting the need for fast reconnection to occur in highly collisional plasma. However, the physical process through which fast magnetic reconnection occurs in partially ionized plasma, like the solar chromosphere, is still poorly understood. It has been shown that for sufficiently high magnetic Reynolds numbers, Sweet-Parker current sheets can become unstable leading to tearing mode instability and plasmoid formation, but when dealing with a partially ionized plasma the strength of coupling between the ions and neutrals plays a fundamental role in determining the dynamics of the system. We propose that as the reconnecting current sheet thins and the tearing instability develops, plasmoid formation passes through strongly, intermediately, and weakly coupled (or decoupled) regimes, with the time scale for the tearing mode instability depending on the frictional coupling between ions and neutrals. We present calculations for the relevant time scales for fractal tearing in all three regimes. We show that as a result of the tearing mode instability and the subsequent non-linear instability due to the plasmoid-dominated reconnection, the Sweet-Parker current sheet tends to have a fractal-like structure, and when the chromospheric magnetic field is sufficiently strong the tearing instability can reach down to kinetic scales, which are hypothesized to be necessary for fast reconnection.

  11. Quantitative Geomorphological Analysis & Land Use/ Land Cover Change Detection of Two Sub-Watersheds in NE region of Punjab, India

    NASA Astrophysics Data System (ADS)

    Kaur, M.; Singh, S.; Verma, V. K.; Pateriya, B.

    2014-11-01

    Morphometric analysis is the measurement and mathematical analysis of the landforms. The delineation of drainage system is of utmost importance in understanding hydrological system of an area, water resource management and it's planning in an effective manner. Morphometric analysis and land use change detection of two sub-watersheds namely Kukar Suha and Ratewal of district Shahid Bhagat Singh Nagar, Punjab, India was carried out for quantitative description of drainage and characterisation. The stream order, stream number, stream length, mean stream length, and other morphometric analysis like bifurcation ratio, drainage density, texture, relief ratio, ruggedness number etc. were measured. The drainage pattern of Kukar Suha and Ratewal is mainly dendritic. The agriculture and settlements came up along the drainage network causes the pattern disturbance in the watershed. The study was undertaken to spotlight the morphometric parameters, their impact on the basin and the land use land cover changes occurred over the period of time. Morphometric parameters such as linear aspect, areal aspect and relief aspect of the watershed are computed. The land use/land cover change was extracted from LISS IV Mx + Cartosat1 PAN data. ASTER data is used to prepare DEM (digital elevation model) and geographical information system (GIS) was used to evaluate various morphometric parameters in ArcGIS10 software.

  12. Nuclear Data Sheets for A = 42

    NASA Astrophysics Data System (ADS)

    Chen, Jun; Singh, Balraj

    2016-07-01

    The experimental data are evaluated for known nuclides of mass number A = 42 (Al, Si, P, S, Cl, Ar, K, Ca, Sc, Ti, V, Cr). Detailed evaluated level properties and related information are presented, including adopted values of level and γ-ray energies, decay data (energies, intensities and placement of radiations), and other spectroscopic data. This work supersedes earlier full evaluations of A = 42 published by B. Singh, J.A. Cameron - Nucl.Data Sheets 92, 1 (2001) and P.M. Endt - Nucl. Phys. A521, 1 (1990); Errata and Addenda Nucl. Phys. A529, 763 (1991); Errata Nucl. Phys. A564, 609 (1993) (also P.M. Endt - Nucl. Phys. A633, 1 (1998) update). No excited states are known in 42Al, 42P, 42V and 42Cr, and structure information for 42Si and 42S is quite limited. There are no decay schemes available for the decay of 42Al, 42Si, 42P, 42V and 42Cr, while the decay schemes of 42Cl and 42Ti are incomplete in view of scarcity of data, and large gap between their Q-values and the highest energy levels populated in corresponding daughter nuclei. Structures of 42Ca, 42K, 42Sc and 42Ar nuclides remain the most extensively studied via many different nuclear reactions and decays.

  13. Investigation on the forced response of a radial turbine under aerodynamic excitations

    NASA Astrophysics Data System (ADS)

    Ma, Chaochen; Huang, Zhi; Qi, Mingxu

    2016-04-01

    Rotor blades in a radial turbine with nozzle guide vanes typically experience harmonic aerodynamic excitations due to the rotor stator interaction. Dynamic stresses induced by the harmonic excitations can result in high cycle fatigue (HCF) of the blades. A reliable prediction method for forced response issue is essential to avoid the HCF problem. In this work, the forced response mechanisms were investigated based on a fluid structure interaction (FSI) method. Aerodynamic excitations were obtained by three-dimensional unsteady computational fluid dynamics (CFD) simulation with phase shifted periodic boundary conditions. The first two harmonic pressures were determined as the primary components of the excitation and applied to finite element (FE) model to conduct the computational structural dynamics (CSD) simulation. The computed results from the harmonic forced response analysis show good agreement with the predictions of Singh's advanced frequency evaluation (SAFE) diagram. Moreover, the mode superposition method used in FE simulation offers an efficient way to provide quantitative assessments of mode response levels and resonant strength.

  14. The Effect of Nickel on the Strength of Hcp-Iron

    NASA Astrophysics Data System (ADS)

    Reagan, M. M.; Gleason, A. E.; Mao, W. L.

    2015-12-01

    Hydrostatic nuclear resonance inelastic x-ray scattering coupled with non-hydrostatic radial x-ray diffraction measurements can be used to determine the shear strength of Fe-bearing materials at core pressures. Using the Singh et al. formalism (2006), the bulk shear strength (t) of a material is related to its shear modulus(G) and to the average differential strain () over all measured lattice planes (hkl) by t = 6G. We followed an existing framework (Gleason & Mao, 2013) and extend the strength determinations to investigate the effect of nickel on the strength of iron at high pressure. We collected radial X-ray diffraction data on Fe90Ni10 and Fe80Ni20 using a panoramic diamond anvil cell with an X-ray transparent gasket to 100 GPa. This data was combined with existing NRIXS data (Lin 2003) to calculate the strength of these compounds. From this we extrapolated the strength of these iron-nickel alloys to deep earth pressures to give a new constraint on the strength of the inner core. Gaining a better understanding of the strength of iron and its alloys at high pressures can shed light on the strength of the inner core and provide insight into the deformation processes operating in the most remote region of our planet.

  15. On Statistical Methods for Common Mean and Reference Confidence Intervals in Interlaboratory Comparisons for Temperature

    NASA Astrophysics Data System (ADS)

    Witkovský, Viktor; Wimmer, Gejza; Ďuriš, Stanislav

    2015-08-01

    We consider a problem of constructing the exact and/or approximate coverage intervals for the common mean of several independent distributions. In a metrological context, this problem is closely related to evaluation of the interlaboratory comparison experiments, and in particular, to determination of the reference value (estimate) of a measurand and its uncertainty, or alternatively, to determination of the coverage interval for a measurand at a given level of confidence, based on such comparison data. We present a brief overview of some specific statistical models, methods, and algorithms useful for determination of the common mean and its uncertainty, or alternatively, the proper interval estimator. We illustrate their applicability by a simple simulation study and also by example of interlaboratory comparisons for temperature. In particular, we shall consider methods based on (i) the heteroscedastic common mean fixed effect model, assuming negligible laboratory biases, (ii) the heteroscedastic common mean random effects model with common (unknown) distribution of the laboratory biases, and (iii) the heteroscedastic common mean random effects model with possibly different (known) distributions of the laboratory biases. Finally, we consider a method, recently suggested by Singh et al., for determination of the interval estimator for a common mean based on combining information from independent sources through confidence distributions.

  16. High-wavenumber solar f-mode strengthening prior to active region formation

    NASA Astrophysics Data System (ADS)

    Singh, Nishant; Raichur, Harsha; Brandenburg, Axel

    2016-05-01

    We report a systematic strengthening of the local solar surface mode, i.e. the f-mode, 1-2 days prior to the emergence of an active region (AR) in the same (corotating) location while no indication can yet be seen in the magnetograms. Our study is motivated by earlier numerical findings of Singh et al. (2014) which showed that, in the presence of a nonuniform magnetic field that is concentrated a few scale heights below the surface, the f-mode fans out in the diagnostic kΩ diagram at high wavenumbers. Here we explore this possibility using data from the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory, and show for four ARs 11130, 11158, 11768, and 12051, that at large latitudinal wavenumbers (corresponding to horizontal scales of around 3000 km), the f-mode displays strengthening about two days prior to AR formation and thus provides a new precursor for AR formation. The idea that the f-mode is perturbed days before any visible magnetic activity occurs on the surface can be important in constraining dynamo models aimed at understanding the global magnetic activity of the Sun.

  17. Evaluation of the Majorana phases of a general Majorana neutrino mass matrix: Testability of hierarchical flavour models

    NASA Astrophysics Data System (ADS)

    Samanta, Rome; Chakraborty, Mainak; Ghosal, Ambar

    2016-03-01

    We evaluate the Majorana phases for a general 3 × 3 complex symmetric neutrino mass matrix on the basis of Mohapatra-Rodejohann's phase convention using the three rephasing invariant quantities I12, I13 and I23 proposed by Sarkar and Singh. We find them interesting as they allow us to evaluate each Majorana phase in a model independent way even if one eigenvalue is zero. Utilizing the solution of a general complex symmetric mass matrix for eigenvalues and mixing angles we determine the Majorana phases for both the hierarchies, normal and inverted, taking into account the constraints from neutrino oscillation global fit data as well as bound on the sum of the three light neutrino masses (Σimi) and the neutrinoless double beta decay (ββ0ν) parameter |m11 |. This methodology of finding the Majorana phases is applied thereafter in some predictive models for both the hierarchical cases (normal and inverted) to evaluate the corresponding Majorana phases and it is shown that all the sub cases presented in inverted hierarchy section can be realized in a model with texture zeros and scaling ansatz within the framework of inverse seesaw although one of the sub cases following the normal hierarchy is yet to be established. Except the case of quasi degenerate neutrinos, the methodology obtained in this work is able to evaluate the corresponding Majorana phases, given any model of neutrino masses.

  18. Environmental Applications of Nanotechnology

    NASA Astrophysics Data System (ADS)

    Keller, Arturo A.

    2014-07-01

    Engineered nanomaterials (ENMs) are currently used in many applications including agriculture (Gruère, 2012; Khot et al. 2012; Lopez-Moreno et al. 2010; Peralta-Videa et al. 2011; Zhao et al. 2012), aerogels (Bigall et al. 2009), aerospace (Baur and Silverman, 2007), automotive (Coelho et al. 2012; Presting and König, 2003; Salonitis et al. 2010), catalysts (Zhou et al. 2011), coatings, paints and pigments (Dhoke et al. 2009; Gopalakrishnan et al. 2011; Khanna, 2008), composites (Borchardt, 2003; Khanna and Bakshi, 2009; Petrov and Georgiev, 2012; Sahoo et al. 2010), construction (Lee et al. 2010), cosmetics (Musee, 2011; Sabitha et al. 2012; Singh and Nanda, 2012), electronics and optics (Alda et al. 2005; Avasthi et al. 2007; Song et al. 2012; Subramanian and Takhee, 2012), energy (Serrano et al. 2009), environmental remediation (Dionysiou 2004; Khin et al. 2012), filtration and purification (Dhakras, 2011; Savage and Diallo, 2005), food products (Blasco and Picó, 2011; Weiss et al. 2006), medical (Boisseau and Loubaton, 2011; Farokhzad and Langer, 2006), packaging (Silvestre et al. 2011), paper and board (Kharisov and Kharissova, 2010), plastics, security (Marín and Merkoçi, 2012), sensors (Ding et al. 2010; Duncan et al. 2012; Su et al. 2012; Tan et al. 2012), and textiles (Qian and Hinestroza, 2004; Wong et al. 2006), and research is underway on many new applications...

  19. Clausius-Clapeyron Scaling of Convective Available Potential Energy (CAPE) in Cloud-Resolving Simulations

    NASA Astrophysics Data System (ADS)

    Seeley, J.; Romps, D. M.

    2015-12-01

    Recent work by Singh and O'Gorman has produced a theory for convective available potential energy (CAPE) in radiative-convective equilibrium. In this model, the atmosphere deviates from a moist adiabat—and, therefore, has positive CAPE—because entrainment causes evaporative cooling in cloud updrafts, thereby steepening their lapse rate. This has led to the proposal that CAPE increases with global warming because the strength of evaporative cooling scales according to the Clausius-Clapeyron (CC) relation. However, CAPE could also change due to changes in cloud buoyancy and changes in the entrainment rate, both of which could vary with global warming. To test the relative importance of changes in CAPE due to CC scaling of evaporative cooling, changes in cloud buoyancy, and changes in the entrainment rate, we subject a cloud-resolving model to a suite of natural (and unnatural) forcings. We find that CAPE changes are primarily driven by changes in the strength of evaporative cooling; the effect of changes in the entrainment rate and cloud buoyancy are comparatively small. This builds support for CC scaling of CAPE.

  20. Mapping Variation in Vegetation Functioning with Imaging Spectroscopy

    NASA Astrophysics Data System (ADS)

    Townsend, P. A.; Couture, J. J.; Kruger, E. L.; Serbin, S.; Singh, A.

    2015-12-01

    Imaging spectroscopy (otherwise known as hyperspectral remote sensing) offers the potential to characterize the spatial and temporal variation in biophysical and biochemical properties of vegetation that can be costly or logistically difficult to measure comprehensively using traditional methods. A number of recent studies have illustrated the capacity for imaging spectroscopy data, such as from NASA's AVIRIS sensor, to empirically estimate functional traits related to foliar chemistry and physiology (Singh et al. 2015, Serbin et al. 2015). Here, we present analyses that illustrate the implications of those studies to characterize within-field or -stand variability in ecosystem functioning. In agricultural ecosystems, within-field photosynthetic capacity can vary by 30-50%, likely due to within-field variations in water availability and soil fertility. In general, the variability of foliar traits is lower in forests than agriculture, but can still be significant. Finally, we demonstrate that functional trait variability at the stand scale is strongly related to vegetation diversity. These results have two significant implications: 1) reliance on a small number of field samples to broadly estimate functional traits likely underestimates variability in those traits, and 2) if trait estimations from imaging spectroscopy are reliable, such data offer the opportunity to greatly increase the density of measurements we can use to predict ecosystem function.

  1. Analytical investigation of the SAFE diagram for bladed wheels, numerical and experimental validation

    NASA Astrophysics Data System (ADS)

    Bertini, L.; Neri, P.; Santus, C.; Guglielmo, A.; Mariotti, G.

    2014-09-01

    Compressor and turbine bladed wheels interact with the fluid distributed by the stator vanes. They are subject to vibration and fatigue loading, especially when resonance conditions are excited. Avoiding resonance is fundamental when designing bladed wheels. The Campbell diagram approach is too conservative since bladed wheels show many close frequency natural modes, thus it is almost impossible to avoid frequency matching. Singh's Advanced Frequency Evaluation (SAFE) diagram, or interference diagram, also introduces shape matching in addition to the frequency, for resonance prediction, therefore many frequency matching cases can be identified as non-critical and thus tolerated. The present paper explains and demonstrates the SAFE diagram by introducing an analytical expression to identify bladed wheel resonance conditions. The mode shape matching with a harmonic component is investigated by means of specific examples. Symmetry properties of the matching distribution of harmonic indices and mode shapes are also introduced and demonstrated. Finally, a bladed wheel analysis is used for validation, both in FE simulations and experiments.

  2. Magnetism and transport properties of layered rare-earth cobaltates Ln0.3CoO2

    NASA Astrophysics Data System (ADS)

    Knížek, K.; Novák, P.; Jirák, Z.; Hejtmánek, J.; Maryško, M.; Buršík, J.

    2015-05-01

    The ab-initio (GGA+U) electronic structure calculations of layered cobaltates Ln0.3CoO2 (Ln = La, Pr, Nd) prepared by ionic exchange from Na0.90CoO2 precursors have been performed. The data are used for numerical modeling of Seebeck coefficient within Boltzmann transport theory using BoltzTraP program [G. K. H. Madsen and D. J. Singh, Comput. Phys. Commun. 175, 67 (2006)], as well as for determination of the crystal field split levels of rare-earth ions using a method based on a transformation of Bloch states into the basis of Wannier functions [P. Novák et al., Phys. Rev. B 87, 205139 (2013)]. An overall agreement with observed magnetism and transport properties is obtained. In particular, the high p-type thermopower is well reproduced in a broad temperature range, but instead of theoretical linear decrease down to the lowest temperatures, the real systems exhibit an anomalous change of Seebeck sign, which might be related to the change of bare metallic carriers into the polaronic ones.

  3. Manufacturing of Wearable Sensors for Human Health and Performance Monitoring

    NASA Astrophysics Data System (ADS)

    Alizadeh, Azar

    2015-03-01

    Continuous monitoring of physiological and biological parameters is expected to improve performance and medical outcomes by assessing overall health status and alerting for life-saving interventions. Continuous monitoring of these parameters requires wearable devices with an appropriate form factor (lightweight, comfortable, low energy consuming and even single-use) to avoid disrupting daily activities thus ensuring operation relevance and user acceptance. Many previous efforts to implement remote and wearable sensors have suffered from high cost and poor performance, as well as low clinical and end-use acceptance. New manufacturing and system level design approaches are needed to make the performance and clinical benefits of these sensors possible while satisfying challenging economic, regulatory, clinical, and user-acceptance criteria. In this talk we will review several recent design and manufacturing efforts aimed at designing and building prototype wearable sensors. We will discuss unique opportunities and challenges provided by additive manufacturing, including 3D printing, to drive innovation through new designs, faster prototyping and manufacturing, distributed networks, and new ecosystems. We will also show alternative hybrid self-assembly based integration techniques for low cost large scale manufacturing of single use wearable devices. Coauthors: Prabhjot Singh and Jeffrey Ashe.

  4. Fanning Out of the Solar f-mode in the Presence of Non-uniform Magnetic Fields?

    NASA Astrophysics Data System (ADS)

    Singh, Nishant K.; Brandenburg, Axel; Rheinhardt, Matthias

    2014-11-01

    We show that in the presence of a magnetic field that is varying harmonically in space, the fundamental mode, or f-mode, in a stratified layer is altered in such a way that it fans out in the diagnostic kω diagram, with mode power also within the fan. In our simulations, the surface is defined by a temperature and density jump in a piecewise isothermal layer. Unlike our previous work (Singh et al. 2014), where a uniform magnetic field was considered, here we employ a non-uniform magnetic field together with hydromagnetic turbulence at length scales much smaller than those of the magnetic field. The expansion of the f-mode is stronger for fields confined to the layer below the surface. In some of those cases, the kω diagram also reveals a new class of low-frequency vertical stripes at multiples of twice the horizontal wavenumber of the background magnetic field. We argue that the study of the f-mode expansion might be a new and sensitive tool to determine subsurface magnetic fields with azimuthal or other horizontal periodicity.

  5. Critical examination of isolation system design paradigms for a coupled powertrain and frame: Partial torque roll axis decoupling methods given practical constraints

    NASA Astrophysics Data System (ADS)

    Liette, Jared; Dreyer, Jason T.; Singh, Rajendra

    2014-12-01

    The torque roll axis motion decoupling concept is analytically and computationally studied in a realistic coupled powertrain and frame system using discrete, proportionally damped linear models. Recently, Hu and Singh (2012 [1]) (Journal of Sound and Vibration 331 (2012) 1498-1518) proposed new paradigms to fully decouple such a system. However, critical examination shows that the derivation does not always lead to a physically realizable system, as each powertrain mount is not referenced to a single location. This deficiency is overcome by deriving mount compatibility conditions to ensure realistic mount positions which are incorporated into proposed decoupling conditions. It is mathematically shown that full decoupling is not possible for a practical system, and therefore partial decoupling paradigms are pursued. Powertrain mount design using only the decoupled powertrain achieves better decoupling than minimizing conditions for the coupled system using a total least squares method. Further decoupling is obtained through frame isolation design using a decoupled frame model such that the torque roll mode is dominant over the frequency range considered. Other methods for limiting frame coupling are also briefly discussed.

  6. Snow cover identification of saline-alkali land in the Western Jilin province of China based on MWRI data

    NASA Astrophysics Data System (ADS)

    Sun, Mingbo; Gu, Lingjia; Ren, Ruizhi; Cao, Qiong

    2016-09-01

    Snow parameters are important physical quantities of climatology and hydrology research, improving the accuracy of snow parameters is important for climatology, hydrology and disaster prevention and reduction. The western Jilin Province of China has obvious salinization problem. Meanwhile, it belongs to a typical snow-covered area. In this paper, the western Jilin Province is selected as the study area and the main research focuses on analyzing the snow cover conditions. The FY3B-MWRI passive microwave remote sensing data from year 2011 to 2016 are selected as experimental data. Compared with optical remote sensing data, using MWRI data can better obtain snow information, and it is also the preliminary work to retrieve snow depth and snow water equivalent. Furthermore, a new decision tree algorithm for snow cover identification was built to distinguish different snow cover conditions. Compared with the existing three algorithms reported in other literatures, the proposed algorithm improves the identification accuracy of snow cover up to 95.06%. While the accuracy for Singh's algorithm, Pan's algorithm and Li's algorithm were about 80.19%, 78.79% and 90.13%, respectively. This study provides important information to the research of snow cover in saline-alkali land.

  7. Higher derivative massive spin-3 models in D =2 +1

    NASA Astrophysics Data System (ADS)

    Dalmazi, D.; Mendonça, E. L.

    2016-07-01

    We find new higher derivative models describing a parity doublet of massive spin-3 modes in D =2 +1 dimensions. One of them is of fourth order in derivatives while the other one is of sixth order. They are complete, in the sense that they contain the auxiliary scalar field required to remove spurious degrees of freedom. Both of them are obtained through the master action technique starting with the usual (second-order) spin-3 Singh-Hagen model, which guarantees that they are ghost free. The fourth- and sixth-order terms are both invariant under (transverse) Weyl transformations, quite similarly to the fourth-order K -term of the "new massive gravity." The sixth-order term slightly differs from the product of the Schouten by the Einstein tensor, both of third order in derivatives. It is also possible to write down the fourth-order term as a product of a Schouten-like by an Einstein-like tensor (both of second order in derivatives) in close analogy with the K -term.

  8. Relation between the increased transmission in the EXAFS region of X-ray absorption and the increase in the number of Abrikosov Vortices as cuprate superconductors go through Tc

    NASA Astrophysics Data System (ADS)

    Chigvinadze, Jaba G.; Mamniashvilli, Gogi I.; Acrivos, Juana V.

    2004-03-01

    The increased flux expulsion as T->Tc (observed as the external magnetic field, Bz = +/- 0.75 oe. goes through zero [1]) is related to the increased transmission as T->Tc (observed in all cuprate superconductors in the EXFAS region of X-ray absorption [2]). The expulsion of Abrikosov vortices as T->Tc is a cooperative dynamic phenomenon that affects only the EXAFS region of the spectrum. When the flux expulsion diverges beyond a critical value, we propose the EXAFS transmission increases because photoelectrons are involved in the Abrikosov Vortex. The phenomenon is similar to the increased transmission observed in He 4 by the formation of supercritical vortices [3]. [1] J.V. Acrivos, Lei Chen, C.M. Burch, P. Metcalf, J.M.Honig, R.S.Liu and K.K.Singh, Phys. Rev. B 50, 13710 (1994), [2] J.V. Acrivos, L.Nguyen, T.Norman, C.T. Lin, W.Y.Liang, J.M Honig and P.Somasundaram, Microchemical Journal, 71, 117 (2002), [3] E.J.Yarmchuk, M.J.V.Gordon, R.E.Packard, Phys.Rev.Lett. 43, 214 (1979)

  9. First-principles search for potential high temperature superconductors in the Mg-B-A (A=alkaline metal) system with high boron content

    NASA Astrophysics Data System (ADS)

    Chepulskyy, Roman; Mazin, Igor; Curtarolo, Stefano

    2008-03-01

    Possible superconductivity at 50K was recently reported [1] in the Mg-B-A (A=Cs, Rb, Ba) system. Although attempts to reproduce this finding have been unsuccessful so far [2], if a stable or metastable phase could be found by a first principle search similar to that in Ref. 3, this would have lent credibility to the experimental finding [1] and outline possible further directions. The results of Ref. 1 suggest that (a) the superconducting phase is not similar to MgB2 (B site has cubic or similarly high symmetry) and (b) boron content is higher than in MgB2. We report first-principles study of the thermodynamics of alkali and alkaline earth doping in the boron- rich part of the Mg-B phase diagram (MgBn with n>2), searching for a phase that could explain the results of Ref. [1]. [1] A.V. Palnichenko et al., JETP Letters 86, 272 (2007). [2] R K Singh et al http://arxiv.org/abs/0709.4001v1. [3] S. Curtarolo et al, Calphad 29, 163 (2005).

  10. Historical Seismograms and Earthquakes of the World

    NASA Astrophysics Data System (ADS)

    Agnew, Duncan

    From the standpoint of the seismologist studying actual waveforms (as opposed to travel times) a new era began in 1963 with the establishment of the World-Wide Standardized Seismograph Network (WWSSN): Well-calibrated seismograms from all over the world were available from a single data distributor. But the life of this network has been brief compared to the repeat times of great earthquakes; to learn about many of these, we must turn to pre-WWSSN seismograms, which extend back to the start of instrumental seismology around 1900. These seismograms, now termed historical seismograms, are a primary subject of this book, a collection of papers derived from a 1985 International Association of Seismologists and Physicists of the Earth's Interior symposium.These older seismograms often contain detailed waveform data that could not be used when they were made but which can now be modeled to determine earthquake source parameters. Papers by H. Kanamori, by S. K. Singh, and by S. Stein, E. Okal, and D. Wiens review this area; Kanamori's paper has an especially valuable discussion of instrument responses and a useful list of large earthquakes, while Stein et al. show the contibution older data can make to understanding areas of low seismicity. Even seismograms of lower quality can be of value, as K. Abe shows by deriving magnitudes and origin times of Chinese and California earthquakes from 1898 through 1912 using recordings made by undamped seismometers.

  11. FAST TRACK COMMUNICATION: Critical phenomena at the 140 and 200 K magnetic phase transitions in BiFeO3

    NASA Astrophysics Data System (ADS)

    Scott, J. F.; Singh, M. K.; Katiyar, R. S.

    2008-08-01

    We have measured the magnon Raman cross-sections for bismuth ferrite as a function of temperature near the newly discovered magnetic phase transitions near T2 = 140.3 ± 0.2 K and T1 = 201.0 ± 0.8 K (Singh et al 2008 J. Phys.: Condens. Matter 20 252203) and evaluate the critical exponents (α = 0.05 and α' = 0.09) characterizing that at 140.3 K and (α = 0.06 and α' = 0.13) that at 201.0 K. These are {\\ll } 1 , and hence the data fit a logarithmic divergence about as well. The occurrence of divergences in the electric susceptibility proportional to the specific heat anomaly in non-ferroelectric transitions due to piezoelectric coupling was first reported by Kizhaev et al (1986 JETP Lett. 43 445); in the present paper we apply an analogous theory to magnetoelastic coupling at magnetic transitions. This is an application of the basic Pippard relationship between susceptibilities and specific heat (Pippard 1956 Phil. Mag. 1 473) to a magnetoelastic system. The observations are related to the mechanical loss anomalies observed at the same temperatures (Redfern et al 2008 Preprint cond-mat). Our results support the distorted spin cycloid model of Zalesskii et al (2003 Phys. Solid State 45 141) and not the earlier model of Sosnowska et al (1982 J. Phys. C: Solid State Phys. 15 4835).

  12. Chlorzoxazone or 1-EBIO increases Na(+) absorption across cystic fibrosis airway epithelial cells.

    PubMed

    Gao, L; Yankaskas, J R; Fuller, C M; Sorscher, E J; Matalon, S; Forman, H J; Venglarik, C J

    2001-11-01

    Previous studies demonstrated that chlorzoxazone or 1-ethyl-2-benzimidazolinone (1-EBIO) enhances transepithelial Cl(-) secretion by increasing basolateral K(+) conductance (G(K)) (Singh AK, Devor DC, Gerlach AC, Gondor M, Pilewski JM, and Bridges RJ. J Pharmacol Exp Ther 292: 778-787, 2000). Hence these compounds may be useful to treat cystic fibrosis (CF) airway disease. The goal of the present study was to determine whether chlorzoxazone or 1-EBIO altered ion transport across Delta F508-CF transmembrane conductance regulator homozygous CFT1 airway cells. CFT1 monolayers exhibited a basal short-circuit current that was abolished by apical amiloride (inhibition constant 320 nM) as expected for Na(+) absorption. The addition of chlorzoxazone (400 microM) or 1-EBIO (2 mM) increased the amiloride-sensitive I(sc) approximately 2.5-fold. This overlapping specificity may preclude use of these compounds as CF therapeutics. Assaying for changes in the basolateral G(K) with a K(+) gradient plus the pore-forming antibiotic amphotericin B revealed that chlorzoxazone or 1-EBIO evoked an approximately 10-fold increase in clotrimazole-sensitive G(K). In contrast, chlorzoxazone did not alter epithelial Na(+) channel-mediated currents across basolateral-permeabilized monolayers or in Xenopus oocytes. These data further suggest that alterations in basolateral G(K) alone can modulate epithelial Na(+) transport.

  13. Nuclear Data Sheets for A = 42

    SciTech Connect

    Chen, Jun; Singh, Balraj

    2016-07-15

    The experimental data are evaluated for known nuclides of mass number A = 42 (Al, Si, P, S, Cl, Ar, K, Ca, Sc, Ti, V, Cr). Detailed evaluated level properties and related information are presented, including adopted values of level and γ–ray energies, decay data (energies, intensities and placement of radiations), and other spectroscopic data. This work supersedes earlier full evaluations of A = 42 published by B. Singh, J.A. Cameron – Nucl.Data Sheets 92, 1 (2001) and P.M. Endt – Nucl. Phys. A521, 1 (1990); Errata and Addenda Nucl. Phys. A529, 763 (1991); Errata Nucl. Phys. A564, 609 (1993) (also P.M. Endt – Nucl. Phys. A633, 1 (1998) update). No excited states are known in {sup 42}Al, {sup 42}P, {sup 42}V and {sup 42}Cr, and structure information for {sup 42}Si and {sup 42}S is quite limited. There are no decay schemes available for the decay of {sup 42}Al, {sup 42}Si, {sup 42}P, {sup 42}V and {sup 42}Cr, while the decay schemes of {sup 42}Cl and {sup 42}Ti are incomplete in view of scarcity of data, and large gap between their Q–values and the highest energy levels populated in corresponding daughter nuclei. Structures of {sup 42}Ca, {sup 42}K, {sup 42}Sc and {sup 42}Ar nuclides remain the most extensively studied via many different nuclear reactions and decays.

  14. Affordable, Robust Ceramic Joining Technology (ARCJoint) Developed

    NASA Technical Reports Server (NTRS)

    Steele, Gynelle C.

    2001-01-01

    Affordable, Robust Ceramic Joining Technology (ARCJoint) is a method for joining high temperature- resistant ceramic pieces together, establishing joints that are strong, and allowing joining to be done in the field. This new way of joining allows complex shapes to be formed by joining together geometrically simple shapes. The joining technology at NASA is one of the enabling technologies for the application of silicon-carbide-based ceramic and composite components in demanding and high-temperature applications. The technology is being developed and tested for high-temperature propulsion parts for aerospace use. Commercially, it can be used for joining ceramic pieces used for high temperature applications in the power-generating and chemical industries, as well as in the microelectronics industry. This innovation could yield big payoffs for not only the power-generating industry but also the Silicon Valley chipmakers. This technology, which was developed at the NASA Glenn Research Center by Dr. Mrityunjay Singh, is a two-step process involving first using a paste to join together ceramic pieces and bonding them by heating the joint to 110 to 120 C for between 10 and 20 min. This makes the joint strong enough to be handled for the final joining. Then, a silicon-based substance is applied to the joint and heated to 1400 C for 10 to 15 min. The resulting joint is as strong as the original ceramic material and can withstand the same high temperatures.

  15. Reply to “Comment on ‘Ground motions from the 2015 Mw 7.8 Gorkha, Nepal, earthquake constrained by a detailed assessment of macroseismic data’ by Stacey S. Martin, Susan E. Hough, and Charleen Hung” by Andrea Tertulliani, Laura Graziani, Corrado Castellano, Alessandra Maramai, and Antonio Rossi

    USGS Publications Warehouse

    Martin, Stacey S.; Hough, Susan E.

    2016-01-01

    We thank Andrea Tertulliani and his colleagues for their interest in our article on the 2015 Gorkha earthquake (Martin, Hough, et al., 2015), and for their comments pertaining to our study (Tertulliani et al., 2016). Indeed, as they note, a comprehensive assessment of macroseismic effects for an earthquake with far‐reaching effects as that of Gorkha is not only critically important but is also an extremely difficult undertaking. In the absence of a widely known web‐based system, employing a well‐calibrated algorithm with which to collect and systematically assess macroseismic information (e.g., Wald et al., 1999; Coppola et al., 2010; Bossu et al., 2015) in the Indian subcontinent, one is left with two approaches to characterize effects of an event such as the Gorkha earthquake: a comprehensive ground‐based survey such as the one undertaken in India following the 2001 Bhuj earthquake (Pande and Kayal, 2003), or an assessment such as Martin, Hough, et al. (2015) akin to other contemporary studies (e.g., Nuttli, 1973; Sieh, 1978; Meltzner and Wald, 1998; Martin and Szeliga, 2010; Ambraseys and Bilham, 2012; Mahajan et al., 2012; Gupta et al., 2013; Singh et al., 2013; Hough and Martin, 2015; Martin and Hough, 2015; Martin, Bradley, et al., 2015; Ribeiro et al., 2015), based primarily upon media reports and other available documentary accounts.

  16. A New Framework for Adaptive Sampling and Analysis During Long- Term Monitoring and Remedial Action Management

    SciTech Connect

    Minsker, Barbara

    2003-06-01

    The Argonne team has gathered available data on monitoring wells and measured hydraulic heads from the Argonne 317/319 site and sent it to UIUC. Xiaodong Li, a research assistant supported by the project, has reviewed the data and is beginning to fit spatiotemporal statistical models to it. Another research assistant, Yonas Demissie, has gotten the site's Modflow model working and is developing a transport model that will be used to generate artificial data. Abhishek Singh, a third research assistant supported by the project, has performed a literature review on inverse modeling and is receiving training on the software that will be used in this project (D2K). He has also created two models of user preferences and successfully implemented them with an interactive genetic algorithm on test functions. Meghna Babbar, the fourth research assistant supported by the project, has created an interactive genetic algorithm code and initial user interface in D2K. Gayathri Gopalakrishnan, the last research assistant who is partially supported by the project, has collected and analyzed data from the phytoremediation systems at the 317/319 site. She has found good correlations between concentrations in the ground water and in branches of the trees, which indicates excellent promise for using the trees as cost-effective long-term monitoring of the contaminants.

  17. Magnetism and transport properties of layered rare-earth cobaltates Ln{sub 0.3}CoO{sub 2}

    SciTech Connect

    Knížek, K. Novák, P.; Jirák, Z.; Hejtmánek, J.; Maryško, M.; Buršík, J.

    2015-05-07

    The ab-initio (GGA+U) electronic structure calculations of layered cobaltates Ln{sub 0.3}CoO{sub 2} (Ln = La, Pr, Nd) prepared by ionic exchange from Na{sub 0.90}CoO{sub 2} precursors have been performed. The data are used for numerical modeling of Seebeck coefficient within Boltzmann transport theory using BoltzTraP program [G. K. H. Madsen and D. J. Singh, Comput. Phys. Commun. 175, 67 (2006)], as well as for determination of the crystal field split levels of rare-earth ions using a method based on a transformation of Bloch states into the basis of Wannier functions [P. Novák et al., Phys. Rev. B 87, 205139 (2013)]. An overall agreement with observed magnetism and transport properties is obtained. In particular, the high p-type thermopower is well reproduced in a broad temperature range, but instead of theoretical linear decrease down to the lowest temperatures, the real systems exhibit an anomalous change of Seebeck sign, which might be related to the change of bare metallic carriers into the polaronic ones.

  18. FANNING OUT OF THE SOLAR f-MODE IN THE PRESENCE OF NON-UNIFORM MAGNETIC FIELDS?

    SciTech Connect

    Singh, Nishant K.; Brandenburg, Axel; Rheinhardt, Matthias

    2014-11-01

    We show that in the presence of a magnetic field that is varying harmonically in space, the fundamental mode, or f-mode, in a stratified layer is altered in such a way that it fans out in the diagnostic kω diagram, with mode power also within the fan. In our simulations, the surface is defined by a temperature and density jump in a piecewise isothermal layer. Unlike our previous work (Singh et al. 2014), where a uniform magnetic field was considered, here we employ a non-uniform magnetic field together with hydromagnetic turbulence at length scales much smaller than those of the magnetic field. The expansion of the f-mode is stronger for fields confined to the layer below the surface. In some of those cases, the kω diagram also reveals a new class of low-frequency vertical stripes at multiples of twice the horizontal wavenumber of the background magnetic field. We argue that the study of the f-mode expansion might be a new and sensitive tool to determine subsurface magnetic fields with azimuthal or other horizontal periodicity.

  19. Microearthquakes at the active Trans-Atlantic Geotraverse (TAG) hydrothermal mound, Mid-Atlantic Ridge, 26°08'N

    NASA Astrophysics Data System (ADS)

    Pontbriand, C.; Reves-Sohn, R. A.

    2010-12-01

    A small 200 m aperture network of five ocean bottom seismometers around the periphery the active TAG hydrothermal mound on the Mid-Atlantic Ridge (26°08’N) detected microearthquake events that may be associated with the subsurface hydraulics of the massive hydrothermal deposit. Seismic data were sampled at 100 Hz for a period of eight months spanning June, 2003 to February, 2004, during which time 24,191 locatable events were detected. Microearthquake hypocenters are concentrated within a 300 m radius of the sulfide mound in the top 250 m of crust, and exhibit a conical shape with the deepest events beneath the mound center. Event rates are steady at 180 events per day at the beginning of the study period and decline slightly to 116 events per day after whale calls elevate background noise levels about 2/3 of the way through the deployment. The mean local magnitude of events is -1.2 with a range of -2.9≦ML≦0.3. We suggest that events may be largely due to hydraulic fracturing of clogged flow conduits in the mineral deposit, which provides the possibility of using the microearthquake data to constrain subsurface flow parameters and the permeability structure of the active TAG deposit. Figure: A bathymetric map of the TAG area depicts a small aperture network of 5 ocean bottom seismometers (white triangles) around the periphery of the active TAG hydrothermal mound. High resolution bathymetry is from Roman and Singh, 2005.

  20. Determination of the drying and rehydration kinetics of freeze dried kiwi ( Actinidia deliciosa) slices

    NASA Astrophysics Data System (ADS)

    Ergün, Kadriye; Çalışkan, Gülşah; Dirim, Safiye Nur

    2016-12-01

    The aim of this study was to determine the drying and rehydration kinetics of freeze dried kiwi slices. Well-known thin layer drying models (Lewis, Page, Modified Page I, Henderson and Pabis, Modified Henderson and Pabis, Logarithmic, Midilli, Modified Midilli, Two-term, Two-term Exponential, Modified Two-term Exponential, and Wang and Singh) were fitted to the experimental data. A nonlinear regression analysis was used to evaluate the parameters of the selected models using statistical software SPSS 16.0. For the freeze drying process of the kiwi slices, the highest R2 value (0.997), and the lowest RMSE (0.018) as well as the χ2 (0.0004) values were obtained from the Two-term Exponential model. The effective moisture diffusivity (Deff) of the freeze dried kiwi slices was calculated with the Fick's diffusion model as 7.302 × 10-10 m2/s. The rehydration behavior was determined using distilled water at different solid-liquid ratios at room temperature (18 ± 1 °C) using Peleg's model. The kinetics of the total soluble solid loss was also determined.

  1. Transport coefficients for the shear dynamo problem at small Reynolds numbers.

    PubMed

    Singh, Nishant K; Sridhar, S

    2011-05-01

    We build on the formulation developed in S. Sridhar and N. K. Singh [J. Fluid Mech. 664, 265 (2010)] and present a theory of the shear dynamo problem for small magnetic and fluid Reynolds numbers, but for arbitrary values of the shear parameter. Specializing to the case of a mean magnetic field that is slowly varying in time, explicit expressions for the transport coefficients α(il) and η(il) are derived. We prove that when the velocity field is nonhelical, the transport coefficient α(il) vanishes. We then consider forced, stochastic dynamics for the incompressible velocity field at low Reynolds number. An exact, explicit solution for the velocity field is derived, and the velocity spectrum tensor is calculated in terms of the Galilean-invariant forcing statistics. We consider forcing statistics that are nonhelical, isotropic, and delta correlated in time, and specialize to the case when the mean field is a function only of the spatial coordinate X(3) and time τ; this reduction is necessary for comparison with the numerical experiments of A. Brandenburg, K. H. Rädler, M. Rheinhardt, and P. J. Käpylä [Astrophys. J. 676, 740 (2008)]. Explicit expressions are derived for all four components of the magnetic diffusivity tensor η(il)(τ). These are used to prove that the shear-current effect cannot be responsible for dynamo action at small Re and Rm, but for all values of the shear parameter.

  2. Therapeutic effect of Artemia enriched with Escherichia coli expressing double-stranded RNA in the black tiger shrimp Penaeus monodon.

    PubMed

    Thammasorn, Thitiporn; Somchai, Parinyachat; Laosutthipong, Chaowanee; Jitrakorn, Sarocha; Wongtripop, Somjai; Thitamadee, Siripong; Withyachumnarnkul, Boonsirm; Saksmerprome, Vanvimon

    2013-10-01

    We exploited Artemia as a double-stranded (ds)RNA-delivery system to combat viral diseases in shrimp. First, the transformed Escherichia coli (E. coli) expressing red fluorescent protein (RFP) was tested in the Artemia enrichment process. RFP signals detectable in the gut of Artemia under confocal microscope were evident for the successful encapsulation. Second, the Artemia enrichment process was performed using E. coli producing Laem-Singh virus (LSNV)-specific dsRNA, which has been previously shown to inhibit the viral infection in the black tiger shrimp Penaeus monodon by intramuscular injection and oral administration. The enriched Artemia nauplii were confirmed to contain dsRNA-LSNV by RT-PCR, and were subjected to the feeding test with P. monodon postlarvae. Quantitative RT-PCR indicated that a number of LSNV copies in most of the treated shrimp were, at least, 1000-fold lower than the untreated controls. During 11-17weeks after feeding, average body weight of the treated group was markedly increased relative to the control group. A smaller differential growth rate of the treated group as compared to the control was also noticed. These results suggested that feeding shrimp with the dsRNA-enriched Artemia can eliminate LSNV infection, which is the cause of retarded growth in P. monodon. The present study reveals for the first time the therapeutic effect of dsRNA-enriched Artemia for shrimp disease control.

  3. Radionuclide and contaminant immobilization in the fluidized bed steam reforming waste products

    SciTech Connect

    Neeway, James J.; Qafoku, Nikolla; Westsik, Joseph H.; Brown, Christopher F.; Jantzen, Carol; Pierce, Eric M.

    2012-05-01

    The goal of this chapter is to introduce the reader to the Fluidized Bed Steam Reforming (FBSR) process and resulting waste form. The first section of the chapter gives an overview of the potential need for FBSR processing in nuclear waste remediation followed by an overview of the engineering involved in the process itself. This is followed by a description of waste form production at a chemical level followed by a section describing different process streams that have undergone the FBSR process. The third section describes the resulting mineral product in terms of phases that are present and the ability of the waste form to encapsulate hazardous and radioactive wastes from several sources. Following this description is a presentation of the physical properties of the granular and monolith waste form product including and contaminant release mechanisms. The last section gives a brief summary of this chapter and includes a section on the strengths associated with this waste form and the needs for additional data and remaining questions yet to be answered. The reader is directed elsewhere for more information on other waste forms such as Cast Stone (Lockrem, 2005), Ceramicrete (Singh et al., 1997, Wagh et al., 1999) and geopolymers (Kyritsis et al., 2009; Russell et al., 2006).

  4. Big Bang Day: 5 Particles - 2. The Quark

    ScienceCinema

    None

    2016-07-12

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 2. The Quark "Three Quarks for Master Mark! Sure he hasn't got much of a bark." James Joyce's Finnegans Wake left its mark on modern physics when physicist Murray Gell Mann proposed this name for a group of hypothetical subatomic particles that were revealed in 1960 as the fundamental units of matter. Basic particles it seems are made up of even more basic units called quarks that make up 99.9% of visible material in the universe.. But why do we know so little about them? Quarks have never been seen as free particles but instead, inextricably bound together by the Strong Force that in turn holds the atomic nucleus together. This is the hardest of Nature's fundamental forces to crack, but recent theoretical advances, mean that the properties of the quark are at last being revealed.

  5. Influence of Delhi Pollution on Aerosol Properties Over Greater Noida

    NASA Astrophysics Data System (ADS)

    Sharma, M.; Singh, R. P.; Kumar, R.

    2015-12-01

    Influence of Delhi Pollution on Aerosol Properties over Greater NoidaManish Sharma1, Ramesh P. Singh2 and Rajesh Kumar3 1Research and Technology Development Centre, Sharda University, Greater Noida, India. 2School of Earth and Environmental Sciences, Schmid College of Science, Chapman University, Orange 92866, USA 3School of Basic Sciences and Research, Sharda University, Greater Noida, India. Delhi capital of India is highly polluted during winter and summer seasons. Due to dominant westerly winds the air mass influence its neighboring city Greater Noida which is located 60 km south east of Delhi. Detailed analysis of multi satellite data and ground observations have been carried out during 2001-2015. The ground observation and satellite data show dynamic aerosol optical parameters over Greater Noida. During winter and summer seasons, dominant westerly wind outflow pollutants of Delhi that mix with the local anthropogenic emissions of Greater Noida influencing aerosol properties at different pressure levels. The characteristics of trace gases and aerosol parameters over Delhi and Greater Noida will be presented. The air quality is severely affected from the outflow of pollutants from Delhi which is threat to people living in the area. Due to dominant winds the air mass further transported towards eastern parts of Indo-Gangetic plains affecting weather conditions of the major cities.

  6. Universal conductivity in a two-dimensional superfluid-to-insulator quantum critical system.

    PubMed

    Chen, Kun; Liu, Longxiang; Deng, Youjin; Pollet, Lode; Prokof'ev, Nikolay

    2014-01-24

    We compute the universal conductivity of the (2+1)-dimensional XY universality class, which is realized for a superfluid-to-Mott insulator quantum phase transition at constant density. Based on large-scale Monte Carlo simulations of the classical (2+1)-dimensional J-current model and the two-dimensional Bose-Hubbard model, we can precisely determine the conductivity on the quantum critical plateau, σ(∞) = 0.359(4)σQ with σQ the conductivity quantum. The universal conductivity curve is the standard example with the lowest number of components where the bottoms-up AdS/CFT correspondence from string theory can be tested and made to use [R. C. Myers, S. Sachdev, and A. Singh, Phys. Rev. D 83, 066017 (2011)]. For the first time, the shape of the σ(iω(n)) - σ(∞) function in the Matsubara representation is accurate enough for a conclusive comparison and establishes the particlelike nature of charge transport. We find that the holographic gauge-gravity duality theory for transport properties can be made compatible with the data if temperature of the horizon of the black brane is different from the temperature of the conformal field theory. The requirements for measuring the universal conductivity in a cold gas experiment are also determined by our calculation.

  7. Where have all the flowers gone: deforestation in the Third World

    SciTech Connect

    Not Available

    1981-01-01

    The papers in this issue (and in its companion issue) describe tropical forest destruction and analyze implications at several levels. The contributions are representative of the major regions of the tropical moist forests (TMFs) - Amazonia, Africa, and Indo-Malaysia - and reveal a process whose ramifications will affect all parts and components of the biosphere. The authors and titles of the 13 paprs are: Norman Myers, Deforestation in the Tropics: Who Gains, Who Loses; William M. Denevan, Swiddens and Cattle Versus Forest: The Imminent Demise of the Amazon Rain Forest Reexamined; Stephen G. Bunker, Impact of Deforestation on Peasant Communities in the Medio Amazonas of Brazil; Susanna B. Hecht, Deforestation in the Amazon Basin: Magnitude, Dynamics and Soil-Resource Effects; K. Twum-Barima, Forests of Ghana - A Diminishing Asset; J. Leroy Deval (English abstract), Man and Development in the Forests of Gabon; J. Leroy Deval, L'Homme et Le Developpement de La Foret du Gabon Dans Le Passe; Faustin Legault (English Translation), Reforestation in the Republic of Gabon; Faustin Legault, Le Reboisement en Republique Gabonaise; Peter S. Ashton, Forest Conditions in the Tropics of Asia and the Far East; Gurmit Singh K.S., Destroying Malaysian Forests; Kuswata Kartawinata, Environmental Consequences of Tree Removal from the Forest in Indonesia; and Robert Goodland, Indonesia's Environmental Progress in Economic Development.

  8. Current Collection in a Magnetic Field

    NASA Technical Reports Server (NTRS)

    Krivorutsky, E. N.

    1997-01-01

    It is found that the upper-bound limit for current collection in the case of strong magnetic field from the current is close to that given by the Parker-Murphy formula. This conclusion is consistent with the results obtained in laboratory experiments. This limit weakly depends on the shape of the wire. The adiabatic limit in this case will be easily surpassed due to strong magnetic field gradients near the separatrix. The calculations can be done using the kinetic equation in the drift approximation. Analytical results are obtained for the region where the Earth's magnetic field is dominant. The current collection can be calculated (neglecting scattering) using a particle simulation code. Dr. Singh has agreed to collaborate, allowing the use of his particle code. The code can be adapted for the case when the current magnetic field is strong. The needed dm for these modifications is 3-4 months. The analytical description and essential part of the program is prepared for the calculation of the current in the region where the adiabatic description can be used. This was completed with the collaboration of Drs. Khazanov and Liemohn. A scheme of measuring the end body position is also proposed. The scheme was discussed in the laboratory (with Dr. Stone) and it was concluded that it can be proposed for engineering analysis.

  9. Evaluating the Thermal Damage Resistance of Reduced Graphene Oxide/Carbon Nanotube Hybrid Coatings

    NASA Astrophysics Data System (ADS)

    David, Lamuel; Feldman, Ari; Mansfield, Elisabeth; Lehman, John; Singh, Gurpreet; National Institute of Standards and Technology Collaboration

    2014-03-01

    Carbon nanotubes and graphene are known to exhibit some exceptional thermal (K ~ 2000 to 4400 W.m-1K-1 at 300K) and optical properties. Here, we demonstrate preparation and testing of multiwalled carbon nanotubes and chemically modified graphene-composite spray coatings for use on thermal detectors for high-power lasers. The synthesized nanocomposite material was tested by preparing spray coatings on aluminum test coupons used as a representation of the thermal detector's surface. These coatings were then exposed to increasing laser powers and extended exposure times to quantify their damage threshold and optical absorbance. The graphene/carbon nanotube (prepared at varying mass% of graphene in CNTs) coatings demonstrated significantly higher damage threshold values at 2.5 kW laser power (10.6 μm wavelength) than carbon paint or MWCNTs alone. Electron microscopy and Raman spectroscopy of irradiated specimens showed that the composite coating endured high laser-power densities (up to 2 kW.cm-2) without significant visual damage. This research is based on work supported by the National Science Foundation (Chemical, Bioengineering, Environmental, and Transport Systems Division), under grant no. 1335862 to G. Singh.

  10. A Rare Case of Extrafollicular Adenomatoid Odontogenic Tumour in the Posterior Region of the Mandible: Misdiagnosed as Residual Cyst

    PubMed Central

    Shivali, Vaid; Pandey, Anil; Khanna, Vidhi D; Khanna, Prateek; Singh, Ashish; Ahuja, Tarun

    2013-01-01

    Adenomatoid odontogenic tumor is a relatively uncommon distinct odontogenic neoplasm. It is an uncommon tumor of odontogenic origin with varying number of ductlike structures and inductive changes in the stroma. It is a benign and slow growing epithelial tumor and represents 3% of all odontogenic tumors. Its occurrence is more common in anterior region of the maxilla than mandible. Most of the adenomatoid odontogenic tumors occur intra-osseously but few peripheral variant have been reported which are attached to the gingival structures. The intra-osseous Adenomatoid odontogenic tumor may be related to unerrupted tooth (follicular varient) or may not (extrafollicular varient) be related to unerrupted tooth. This paper is to present a rare case of an extrafollicular Adenomatoid odontogenic tumor occurring in the body of the mandible in a male patient which is distinct and secondly it was clinically and radiographically diagnosed as residual cyst. The diagnosis of Adenomatoid odontogenic tumor was confirmed by Histopathological investigation. How to cite this article: Shivali V, Khanna VD, Khanna P, Singh A, Pandey A, Ahuja T. A Rare Case of Extrafollicular Adenomatoid Odontogenic Tumour in the Posterior Region of the Mandible: Misdiagnosed as Residual Cyst. J Int Oral Health 2013; 5(5):124-8. PMID:24324316

  11. Yoga therapy for promoting emotional sensitivity in University students

    PubMed Central

    Ganpat, Tikhe Sham; Dash, Sasmita; Ramarao, Nagendra Hongasandra

    2014-01-01

    Background: Students need emotional intelligence (EI) for their better academic excellence. There are three important psychological dimensions of EI: Emotional sensitivity (ES), emotional maturity (EM) and emotional competency (EC), which motivate students to recognize truthfully, interpret honestly and handle tactfully the dynamics of their behavioral pattern. Objective: The study was designed to assess ES in the students undergoing yoga therapy program in the form of yoga instructor's course (YIC) module. Materials and Methods: One hundred and eighty four YIC students with 25.77 ± 4.85 years of mean age participated in this study of 21 days duration (a single group pre-post design). The ES data was collected before (pre) and after (post) YIC module using Emotional Quotient test developed by Dr Dalip Singh and Dr N K Chadha. Statistical Analysis: Means, standard deviations, Kolmogorov-Smirnov test, and Wilcoxon signed rank test were used for analyzing the data with the help of SPSS 16. Results: The data analysis showed 3.63% significant increase (P < 0.01) in ES. Conclusion: The present study suggests that YIC module can result in improvement of ES among university students, thus paving the way for their academic success. Additional well-designed studies are needed before a strong recommendation can be made. PMID:25013838

  12. Rapid estimation of fault parameters for tsunami warning along the Mexican subduction zone based on real-time GPS (Invited)

    NASA Astrophysics Data System (ADS)

    Perez-Campos, X.; Singh, S. K.; Melgar, D.; Cruz Atienza, V. M.; Iglesias, A.; Hjorleifsdottir, V.

    2013-12-01

    A reliable and robust tsunami early warning is now possible thanks to the availability of real-time GPS data. With few assumptions regarding the characteristics of the geometry of the subduction interface (dip, width of the seismogenic zone, and maximum depth of the seismically-coupled interface), we can estimate the length, L, and the width, W, of the rupture, as well as its downdip extension, C (Singh et al., 2008; 2012). These are estimated from the amplitude of the observed horizontal displacement along the coast and its fall off with distance, as well as the polarity of the vertical displacement. Based on Okada's (1992) model, we compute the slip D on the fault, to finally obtain the seismic moment, Mo. Pérez-Campos et al. (2013) showed the feasibility of such tsunami early warning for the Mexican subduction zone. Mo could be obtained in ~2 min after origin time from a dense distribution of real-time high-rate GPS stations along the coast. However, the current GPS network is sparse. Despite this, a robust estimate of magnitude Mw can be obtained. For this work, we perform sensitivity tests for Mw and position of the fault with respect to the trench.

  13. Rectification of the chordal axis transform and a new criterion for shape decomposition.

    SciTech Connect

    Prasad, Lakshman

    2004-01-01

    In an earlier work we proposed the chordal axis transform (CAT) as a more useful alternative to the medial axis transform (MAT) for obtaining skeletons of discrete shapes. Since then, the CAT has benefited various applications in 2D and 3D shape analysis. In this paper, we revisit the CAT to address its deficiencies that are an artifact of the underlying constrained Delaunay triangulation (CDT). We introduce a valuation on the internal edges of a discrete shape's CDT based on a concept of approximate co-circularity. This valuation provides a basis for suppression of the role of certain edges in the construction of the CAT skeleton. The result is a rectified CAT skeleton that has smoother branches as well as branch points of varying degrees, unlike the original CAT skeleton whose branches exhibit oscillations in tapered sections of shapes and allows only degree 3 branch points. Additionally, the valuation leads to a new criterion for parsing shapes into visually salient parts that closely resemble the empirical decompositions of shapes by human subjects as recorded in experiments by M. Singh, G. Seyranian, and D. Hoffinan.

  14. Optimization and kinetic studies on treatment of textile dye wastewater using Pleurotus floridanus

    NASA Astrophysics Data System (ADS)

    Sathian, S.; Radha, G.; Shanmugapriya, V.; Rajasimman, M.; Karthikeyan, C.

    2013-03-01

    Treatment of textile dye wastewater was carried using Pleurotus floridanus in a batch reactor. Response surface methodology (RSM) was used to optimize the process parameters like pH, temperature, agitation speed and dye wastewater concentration for the decolorization of textile dye wastewater. The optimum conditions for the maximum decolorization was: pH 6.6, temperature 28.8 °C, agitation speed 183 rpm and dye wastewater concentration 1:2. From the results it was found that, the linear effect of agitation speed and initial textile dye wastewater concentration were more significant than other factors for the textile dye wastewater treatment. At these optimized conditions, the maximum decolorization and COD reduction was found to be 71.2 and 80.5 %, respectively. Kinetics of textile dye degradation process was studied by various models like first order, diffusional and Singh model. From the results it was found that the degradation follows first order model with R 2 value of 0.9550.

  15. Animal Bite Injuries in Children: Review of Literature and Case Series

    PubMed Central

    Kumar, Pradeep; Singhal, Ruchi; Singh, Virendra; Bhagol, Amrish

    2017-01-01

    Introduction Maxillofacial region in children is particularly vulnerable to animal bite injuries. These injuries may range from insignificant scratches to life-threatening neck and facial injuries. Children are the common victims, particularly of dog bites. Materials and methods Three cases of animal bite injuries in children with their clinical presentation and their management are being presented along with review of literature. Surgical management included cleansing and primary closure of the wound. Rabies and tetanus prophylaxis were given. Discussion The most common site of injury was the face. For the facial injuries, the most frequently affected area was the middle third (55%), also called as the “central target area.” The small stature of children, the disproportionate size of the head relative to the body, their willingness to bring their faces close to the animal, and limited motor skills to provide defense are believed to account for this. The resulting soft-tissue injuries can vary in relation to their extent. Treatment involved initial surgical exploration, and secondary repair later depending on the severity of the injury. Conclusion Prompt assessment and treatment can prevent most bite wound complications. Early management of such injuries usually guarantees satisfactory outcome. Prevention strategies include close supervision of child-dog interactions, better reporting of bites, etc. How to cite this article Agrawal A, Kumar P, Singhal R, Singh V, Bhagol A. Animal Bite Injuries in Children: Review of Literature and Case Series. Int J Clin Pediatr Dent 2017;10(1):67-72. PMID:28377659

  16. Identification of a new species of Cercospora causing leaf spot disease in Capsicum assamicum in northeastern India.

    PubMed

    Meghvansi, Mukesh K; Khan, Mohammad Haneef; Gupta, Rajeev; Veer, Vijay

    2013-11-01

    Northeastern India is one of the most important biodiversity hotspots in the world. However, hot and humid climatic conditions of the region favor growth and development of foliar fungal phytopathogens such as cercosporoid fungi. The genus Cercospora is one of the largest genera of hyphomycetes. Species of Cercospora are known to cause leaf spot disease in several cultivated and non-cultivated plants leading to considerable losses. In this study, we describe a new species of Cercospora which was isolated from the leaves of Naga chilli (Capsicum assamicum Purkayastha & Singh) grown in northeastern India. Comparison of the detailed morphological characteristics along with the DNA sequences for four gene regions, namely actin, calmodulin, histone H3 and translation elongation factor-1α of this isolate, was made with those of some previously reported Cercospora species infecting Capsicum and other similar species of Cercospora from other hosts. The results suggested that our isolate represents an undescribed taxon and warrants the establishment of a new species, Cercospora tezpurensis sp. nov.

  17. Task before Indian Psychiatry Today: Commentary

    PubMed Central

    De Sousa, Avinash

    2016-01-01

    In this commentary on the article, “The Task Before Psychiatry Today Redux: STSPIR,” (Singh, 2014)[20], the author, while agreeing with most of the paper's findings, proposes a rather parallel judgment that intersects at the same paths ahead. There is a need for widespread and easily available essential mental health services in India. Health agenda must focus on spreading and scaling up psychiatric services. There is also a need to spread awareness of psychiatry and mental health and, as a psychiatrist, one must focus on making psychiatry available to a wider audience. Psychiatrists need to maintain a holistic view of psychiatric disorders while viewing them from both a neurobiological and psychosocial perspective. There is a need to revamp psychiatric training in departments with an increase in the thrust toward fostering translational research excellence in various spheres. Psychiatrists must continue to be trained in psychotherapy and practice it regularly. Psychiatric departments need to promote research excellence and focus on reducing brain drain. The practical applications of the tasks set out for psychiatry are more difficult than one can imagine, and a conscientious effort in that direction shall serve for its betterment. The future is bright and psychiatry must work toward making it brighter. PMID:28031626

  18. The immunohistochemical characterization of devil facial tumor disease (DFTD) in the Tasmanian Devil (Sarcophilus harrisii).

    PubMed

    Loh, R; Hayes, D; Mahjoor, A; O'Hara, A; Pyecroft, S; Raidal, S

    2006-11-01

    Immunohistochemical techniques were used to characterize the disfiguring and debilitating fatal neoplastic disease, devil facial tumor disease (DFTD), which has recently affected a significant proportion of the wild population of Tasmanian Devils (Sarcophilus harrisii). The diagnostic values of a number of immunohistochemical stains were employed to further characterize 50 representative cases. The neoplasms were negative for cytokeratin (0/48), epithelial membrane antigen (0/42), von Willebrand factor (vWF) (0/11), smooth muscle actin (SMA) (0/26), desmin (0/47), glial fibrillary acid protein (0/13), CD16 (0/13), CD57 (0/43), CD3 (0/18), and LSP1 (0/16). DFTD cells were positive for vimentin (50/50), S-100 (41/48), melan A (11/39), neuron specific enolase (35/35), chromogranin A (12/12) and synaptophysin (29/30). The cells were negative for amyloid (0/30) and stained negatively with Singh's silver (0/34) but were weakly argyrophilic (3/40) using Grimelius histochemical stain. These staining characteristics are consistent with cells of neuroectodermal origin.

  19. The Toxicology of Carbon Nanotubes

    NASA Astrophysics Data System (ADS)

    Donaldson, Ken; Poland, Craig; Duffin, Rodger; Bonner, James

    2012-06-01

    1. Carbon nanotube structure, synthesis and applications C. Singh and W. Song; 2. The aerodynamic behaviour and pulmonary deposition of carbon nanotubes A. Buckley, R. Smith and R Maynard; 3. Utilising the concept of the biologically effective dose to define the particle and fibre hazards of carbon nanotubes K. Donaldson, R. Duffin, F. Murphy and C. Poland; 4. CNT, biopersistence and the fibre paradigm D. Warheit and M. DeLorme; 5. Length-dependent retention of fibres in the pleural space C. Poland, F. Murphy and K. Donaldson; 6. Experimental carcinogenicity of carbon nanotubes in the context of other fibres K. Unfried; 7. Fate and effects of carbon nanotubes following inhalation J. Ryman-Rasmussen, M. Andersen and J. Bonner; 8. Responses to pulmonary exposure to carbon nanotubes V. Castranova and R. Mercer; 9. Genotoxicity of carbon nanotubes R. Schins, C. Albrecht, K. Gerloff and D. van Berlo; 10. Carbon nanotube-cellular interactions; macrophages, epithelial and mesothelial cells V. Stone, M. Boyles, A. Kermanizadeh, J. Varet and H. Johnston; 11. Systemic health effects of carbon nanotubes following inhalation J. McDonald; 12. Dosimetry and metrology of carbon nanotubes L. Tran, L. MacCalman and R. Aitken; Index.

  20. Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndrome primary skin fibroblasts

    PubMed Central

    Schenkel, Laila C.; Singh, Ratnesh K.; Michel, Vera; Zeisel, Steven H.; da Costa, Kerry-Ann; Johnson, Amy R.; Mudd, Harvey S.; Bakovic, Marica

    2015-01-01

    Fibroblasts from a patient with postural orthostatic tachycardia syndrome (POTS), who presented with low plasma choline and betaine, were studied to determine the metabolic characteristics of the choline deficiency. Choline is required for the synthesis of the phospholipid phosphatidylcholine (PC) and for betaine, an important osmoregulator. Here, choline transport, lipid homeostasis, and mitochondria function were analyzed in skin fibroblasts from POTS and compared with control cells. The choline transporter-like protein 1/solute carrier 44A1 (CTL1/SLC44A1) and mRNA expression were 2–3 times lower in POTS fibroblasts, and choline uptake was reduced 60% (P < 0.05). Disturbances of membrane homeostasis were observed by reduced ratios between PC:phosphatidylethanolamine and sphingomyelin:cholesterol, as well as by modified phospholipid fatty acid composition. Choline deficiency also impaired mitochondria function, which was observed by a reduction in oxygen consumption, mitochondrial potential, and glycolytic activity. When POTS cells were treated with choline, transporter was up-regulated, and uptake of choline increased, offering an option for patient treatment. The characteristics of the POTS fibroblasts described here represent a first model of choline and CTL1/SLC44A1 deficiency, in which choline transport, membrane homeostasis, and mitochondrial function are impaired.—Schenkel, L. C., Singh, R. K., Michel, V., Zeisel, S. H., da Costa, K.-A., Johnson, A. R., Mudd, H. S., Bakovic, M. Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndrome primary skin fibroblasts. PMID:25466896

  1. The global financial crisis and the Great Recession of 2007-2009.

    PubMed

    Dore, Mohammed H I; Singh, Rajiv G

    2010-07-01

    This paper is a re-examination of the global financial crisis that began in and was accompanied by the most severe recession since the Great Depression. It builds on our earlier paper (Dore and Singh, 2009) and expands its scope. It is divided into parts. The first part deals with the ideological backdrop in which this crisis occurred, namely the belief in the rationality and stability of all markets including the capital markets, called the 'efficient market hypothesis.' The second part is a survey of the role of income distribution and its relations to aggregate spending and the growing role played by credit in the circular flow of income. The third part examines some features of the business cycle expansion phase of to . The fourth part is a brief report on a nonlinear Vector Error Correction model spanning the period to and how this expansion came to an end. The fifth part is a brief comparison of the Great Recession with the Great Depression. Finally in the sixth part, the international impact of the Great Recession is considered briefly, followed by some conclusions.

  2. The "other" side of labor reform: accounts of incarceration and resistance in the Straits Settlements penal system, 1825-1873.

    PubMed

    Pieris, Anoma

    2011-01-01

    The rhetoric surrounding the transportation of prisoners to the Straits Settlements and the reformative capacity of the penal labor regime assumed a uniform subject, an impoverished criminal, who could be disciplined and accordingly civilized through labor. Stamford Raffles, as lieutenant governor of Benkulen, believed that upon realizing the advantages of the new colony, criminals would willingly become settlers. These two colonial prerogatives of labor and population categorized transportees into laboring classes where their exploitation supposedly brought mutual benefit. The colonized was collectively homogenized as a class of laborers and evidence to the contrary, of politically challenging and resistant individuals was suppressed. This paper focuses on two prisoners who were incriminated during the anti-colonial rebellions of the mid-nineteenth century and were transported to the Straits Settlements. Nihal Singh, a political prisoner from Lahore, was incarcerated in isolation to prevent his martyrdom and denied the supposed benefits of labor reform. Conversely, Tikiri Banda Dunuwille, a lawyer from Ceylon was sent to labor in Melaka as a form of humiliation. Tikiri’s many schemes to evade labor damned him in the eyes of the authorities. The personal histories of these two individuals expose how colonial penal policy recognized and manipulated individual differences during a time of rising anti-colonial sentiment. The experiences of these prisoners, the response of their communities and the voices of their descendents offer us a very different entry point into colonial penal history.

  3. Big Bang Day: 5 Particles - 2. The Quark

    SciTech Connect

    2009-10-07

    Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 2. The Quark "Three Quarks for Master Mark! Sure he hasn't got much of a bark." James Joyce's Finnegans Wake left its mark on modern physics when physicist Murray Gell Mann proposed this name for a group of hypothetical subatomic particles that were revealed in 1960 as the fundamental units of matter. Basic particles it seems are made up of even more basic units called quarks that make up 99.9% of visible material in the universe.. But why do we know so little about them? Quarks have never been seen as free particles but instead, inextricably bound together by the Strong Force that in turn holds the atomic nucleus together. This is the hardest of Nature's fundamental forces to crack, but recent theoretical advances, mean that the properties of the quark are at last being revealed.

  4. Selective amino acid substitutions convert the creatine transporter to a gamma-aminobutyric acid transporter.

    PubMed

    Dodd, Joanna R; Christie, David L

    2007-05-25

    The creatine transporter (CRT) is a member of a large family of sodium-dependent neurotransmitter and amino acid transporters. The CRT is closely related to the gamma-aminobutyric acid (GABA) transporter, GAT-1, yet GABA is not an effective substrate for the CRT. The high resolution structure of a prokaryotic homologue, LeuT has revealed precise details of the substrate binding site for leucine (Yamashita, A., Singh, S. K., Kawate, T., Jin, Y., and Gouaux, E. (2005) Nature 437, 215-223). We have now designed mutations based on sequence comparisons of the CRT with GABA transporters and the LeuT structural template in an attempt to alter the substrate specificity of the CRT. Combinations of two or three amino acid substitutions at four selected positions resulted in the loss of creatine transport activity and gain of a specific GABA transport function. GABA transport by the "gain of function" mutants was sensitive to nipecotic acid, a competitive inhibitor of GABA transporters. Our results show LeuT to be a good structural model to identify amino acid residues involved in the substrate and inhibitor selectivity of eukaryotic sodium-dependent neurotransmitter and amino acid transporters. However, modification of the binding site alone appears to be insufficient for efficient substrate translocation. Additional residues must mediate the conformational changes required for the diffusion of substrate from the binding site to the cytoplasm.

  5. Ancient Black Hole Speeds Through Sun's Galactic Neighborhood, Devouring Companion Star

    NASA Astrophysics Data System (ADS)

    2001-09-01

    1118+480 orbits the Galaxy's center in a path similar to those of the globular clusters, moving at 145 kilometers per second (90 miles per second) relative to the Earth. How did it get into such an orbit? "There are two possibilities: either it formed in the Galaxy's plane and was somehow kicked out of the plane or it formed in a globular cluster and was kicked out of the cluster," said Vivek Dhawan, an astronomer at the National Radio Astronomy Observatory (NRAO) in Socorro, New Mexico. A massive star ends its life by exploding as a supernova, leaving either a neutron star or a black hole as a remnant. Some neutron stars show rapid motion, thought to result from a sideways "kick" during the supernova explosion. "This black hole has much more mass -- about seven times the mass of our Sun -- than any neutron star," said Dhawan. "To accelerate it to its present speed would require a kick from the supernova that we consider improbable," Dhawan added. "We think it's more likely that it was gravitationally ejected from the globular cluster," Dhawan said. Simulations of the gravitational interactions in globular clusters have shown that the black holes resulting from the collapse of the most massive stars should eventually be ejected from the cluster. "The star that preceded this black hole probably formed in a globular cluster even before our Galaxy's disk was formed," Mirabel said. "What we're doing here is the astronomical equivalent of archaeology, seeing traces of the intense burst of star formation that took place during an early stage of our Galaxy's development." The black hole has consumed so much of its companion star that the inner layers of the smaller star -- only about one-third the mass of the Sun -- now are exposed. The scientists believe the black hole captured the companion before being ejected from the globular cluster, as if it were grabbing a snack for the road. The Very Long Baseline Array "Because this microquasar happened to be relatively close to the

  6. Repeating and not so Repeating Large Earthquakes in the Mexican Subduction Zone

    NASA Astrophysics Data System (ADS)

    Hjorleifsdottir, V.; Singh, S.; Iglesias, A.; Perez-Campos, X.

    2013-12-01

    The rupture area and recurrence interval of large earthquakes in the mexican subduction zone are relatively small and almost the entire length of the zone has experienced a large (Mw≥7.0) earthquake in the last 100 years (Singh et al., 1981). Several segments have experienced multiple large earthquakes in this time period. However, as the rupture areas of events prior to 1973 are only approximately known, the recurrence periods are uncertain. Large earthquakes occurred in the Ometepec, Guerrero, segment in 1937, 1950, 1982 and 2012 (Singh et al., 1981). In 1982, two earthquakes (Ms 6.9 and Ms 7.0) occurred about 4 hours apart, one apparently downdip from the other (Astiz & Kanamori, 1984; Beroza et al. 1984). The 2012 earthquake on the other hand had a magnitude of Mw 7.5 (globalcmt.org), breaking approximately the same area as the 1982 doublet, but with a total scalar moment about three times larger than the 1982 doublet combined. It therefore seems that 'repeat earthquakes' in the Ometepec segment are not necessarily very similar one to another. The Central Oaxaca segment broke in large earthquakes in 1928 (Mw7.7) and 1978 (Mw7.7) . Seismograms for the two events, recorded at the Wiechert seismograph in Uppsala, show remarkable similarity, suggesting that in this area, large earthquakes can repeat. The extent to which the near-trench part of the fault plane participates in the ruptures is not well understood. In the Ometepec segment, the updip portion of the plate interface broke during the 25 Feb 1996 earthquake (Mw7.1), which was a slow earthquake and produced anomalously low PGAs (Iglesias et al., 2003). Historical records indicate that a great tsunamigenic earthquake, M~8.6, occurred in the Oaxaca region in 1787, breaking the Central Oaxaca segment together with several adjacent segments (Suarez & Albini 2009). Whether the updip portion of the fault broke in this event remains speculative, although plausible based on the large tsunami. Evidence from the

  7. Raman scattering investigation of VOCs in interaction with ice particles

    NASA Astrophysics Data System (ADS)

    Facq, Sébastien; Oancea, Adriana; Focsa, Cristian; Chazallon, Bertrand

    2010-05-01

    formed. These results are finally compared with those obtained by co-deposition trapping process. [1] K. Liou, "Influence of Cirrus Clouds on Weather and Climate Processes: A Global Perspective," Monthly Weather Review, vol. 114, Juin. 1986, pp. 1167-1199. [2] A. Heymsfield and R. Sabin, "Cirrus crystal nucleation by homogeneous freezing of solution droplets," Journal of the Atmospheric Sciences, vol. 46, 1989, pp. 2252-2264. [3] J.P.D. Abbatt, "Interactions of Atmospheric Trace Gases with Ice Surfaces: Adsorption and Reaction," Chemical Reviews, vol. 103, Déc. 2003, pp. 4783-4800. [4] H. Singh, Y. Chen, A. Staudt, D. Jacob, D. Blake, B. Heikes, et J. Snow, "Evidence from the Pacific troposphere for large global sources of oxygenated organic compounds," Nature, vol. 410, Avr. 2001, pp. 1078-1081. [5] H.B. Singh, M. Kanakidou, P.J. Crutzen, and D.J. Jacob, "High concentrations and photochemical fate of oxygenated hydrocarbons in the global troposphere," Nature, vol. 378, Nov. 1995, pp. 50-54.

  8. Coherent Doppler Lidar for Wind and Cloud Measurements on Venus from an Orbiting or Floating/Flying Platform

    NASA Astrophysics Data System (ADS)

    Singh, Upendra; Limaye, Sanjay; Emmitt, George; Kavaya, Michael; Yu, Jirong; Petros, Mulugeta

    an orbiting or floating/flying platform. This presentation will describe the concept, simulation and technology development plan for wind and cloud measurements on Venus. References [1] M.J. Kavaya, U.N. Singh, G.J. Koch, B.C. Trieu, M. Petros, and P.J. Petzar, "Development of a Compact, Pulsed, 2-Micron, Coherent-Detection, Doppler Wind Lidar Transceiver and Plans for Flights on NASA's DC-8 and WB-57 Aircraft," Coherent Laser Radar Conference, Toulouse, France, June 2009. [2] G.J. Koch, J.Y. Beyon, B.W. Barnes, M. Petros, J. Yu, F. Amzajerdian, M.J. Kavaya, and U.N. Singh, "High-Energy 2-micron Doppler Lidar for Wind Measurements," Optical Engineering 46(11), 116201-14 (2007). [3] J.Y. Beyon and G.J. Koch, "Novel Nonlinear Adaptive Doppler Shift Estimation Technique for the Coherent Doppler Validation Lidar," Optical Engineering 46(1), 0160021-9 (2007).

  9. Characterization of CO2 leakage into the freshwater body

    NASA Astrophysics Data System (ADS)

    Singh, Ashok; Delfs, Jens-Olaf; Shao, Habing; Kolditz, Olaf

    2013-04-01

    Current research into Carbon dioxide Capture and Storage (CCS) is dominated by improving the CO2 storage capacity. However, potential leakage of CO2 can cause environmental problems, particularly if freshwater resources are nearby. In this regards, it is important to understand the chemistry of CO2 and the water system. CO2 leakage across the fluid interface (CO2 and water) is controlled by the difference in the partial pressure of CO2 in the storage and in the freshwater body. Once the CO2 is in solution, it equilibrates with the bicarbonate and carbonate ions. According to Millero (1994)such a system can be characterized by two parameters out of the four: total alkalinity (TA), total carbonate (TCO2), fugacity of CO2(fCO2) and pH. In the present modeling study, we are interested in the (i) CO2 leakage into a freshwater body (while injecting CO2 for storage) through an inclined fracture and (ii) characterization of the system by measuring fugacity of CO2 and pH. According to work presented by Singh et al. (2012), about 31% of injected CO2 leaks into the freshwater body. Solubility of CO2 in water follows Henry's law, while the Henry constant, K0 is calculated by an empirical relation developed by Murray and Riley (1971), which is a function of salinity and temperature. According to our results, pH and fugacity both appear to be a linear function of temperature. To simulate the discussed problem, a corresponding numerical module has been developed for multi-component fluid flow coupled with heat and mass transport processes. Governing equations and Volume Translated Peng-Robinson equations of state are implemented within the object-oriented finite element code OpenGeoSys (Kolditz et al., 2012; www.opengeosys.org). Primary variables are pressure, temperature and salinity which are obtained by solving the governing equations in a monolithic way The governing equations are discretized spatially within the context of a Galerkin approach, whereas the temporal

  10. Geochemical proxies for weathering and provenance of Late Quaternary alluvial core-sediments from NW India

    NASA Astrophysics Data System (ADS)

    Singh, Ajit; Amir, Mohd; Paul, Debajyoti; Sinha, Rajiv

    2014-05-01

    The Indo-Gangetic alluvial plains are formed by sediment deposition in the foreland basin as a result of upliftment and subsequent erosion of the Himalaya. Earlier study (Sinha et al., 2013) has shown the subsurface existence of buried channel bodies beneath the Ghaggar plains in NW Indo-Gangetic plains. The mapped sand bodies follow trace of a paleochannel that begins at the mountain front near the exit of river Sutlej and extends to the northern margin of the Thar desert, suggesting existence of a large Himalayan-sourced river (Singh et al., 2011) in the past. The buried sand bodies hold potential records of erosion history over the Himalaya that could be used to assess climate-controlled erosion over the Himalaya. Geochemical variations in the sediments from two (~45m long) cores drilled below the trace of the paleochannel (upstream) near Sirhind, Punjab and two cores (GS-10 & 11) from downstream near Kalibangan, Rajasthan, are used in this study to understand the erosional pattern over the Himalaya during Late Quaternary. Down-core variations in chemical index of alteration (CIA=51-79) along with K2O/Na2O and Al2O3/(CaO+Na2O) ratios are consistent with the trends of SW summer monsoonal fluctuations during the Glacial-Interglacial periods indicating climate controlled weathering at the source; higher values during Interglacial and lower during Glacial periods with maximum value during the Holocene. Sr-Nd isotopic compositions of drill-cores sediments, 87Sr/86Sr (0.7314-0.7946), ɛNd (-23.2 to -14) are within the range of silicate rocks from the Higher and Lesser Himalaya. Significant down-core variations in 87Sr/86Sr and ɛNd are observed that reflect the mixing of varying proportions of the Higher and Lesser Himalayan sediments, the two dominant sources to the core sites. Sediments deposited during MIS-2 and MIS-4, cold and dry Glacial periods, show high 87Sr/86Sr and low ɛNd suggesting an enhanced contribution from the Lesser Himalayan rocks that are

  11. Mathematical and numerical analysis of non-planer static mode-II crack in a two-layered medium

    NASA Astrophysics Data System (ADS)

    Hirano, S.; Yamashita, T.

    2009-12-01

    A crack in an infinite homogeneous medium is widely assumed as a model for earthquake fault. It is, however, well known that the earth's crust is heterogeneous and its structure is approximated well by a layered medium. Hence, such structure should be taken into account to model earthquake fault reasonably. We mathematically analyze the behavior of a 2-D static mode-II non-planar crack in a two-layered elastic medium in order to understand the effect of layer boundary on earthquake faulting. Although Rani and Singh (1993) and Rivalta et al.(2002) studied similar problems, focuses of their studies were quite narrow probably because of inherent mathematical difficulty. Actually the former assumed a planar crack with uniform slip and the latter assumed a planar crack perpendicular to the layer boundary. While a serious difficulty of the analysis of mode-II crack lies in the derivation of stress distribution due to point source as a kernel function, we first overcome the difficulty by writing its expression in a sequence of complex functions in the real (not the Fourier) domain. A very important characteristic in the sequence is that it has recursive property, which makes possible to derive the kernel function explicitly and to integrate it by parts; the integration by parts is required before the boundary integral equation method (BIEM) is applied. Our kernel function is much easier to treat than the expression given by Rani and Singh (1993). This enables us to analyze arbitrarily oriented non-planar crack in a two-layered medium. Next, we calculate the spatial distribution of stress due to crack that does not intersect the layer boundary using the above derived kernel function. We find in the calculation that the existence of layer boundary amplifies or reduces the stress at the crack tip when the crack is located close to the boundary; the stress is amplified when the crack exists in the layer with lower rigidity. Our method of analysis can easily be applied to the

  12. Areas of slip of recent earthquakes in the Mexican subduction zone

    NASA Astrophysics Data System (ADS)

    Hjorleifsdottir, V.; Sánchez-Reyes, H. S.; Singh, S.; Ji, C.; Iglesias, A.; Perez-Campos, X.

    2012-12-01

    The Mexican subduction zone is unusual: the width of the seismogenic zone is relatively narrow and a large portion of the co-seismic slip generally occurs below the coast, ~ 45 to 80 km from the trench. The earthquake recurrence interval is relatively short and almost the entire length of the zone has experienced a large (Mw≥7.4) earthquake in the last 100 years (Singh et al., 1981). In this study we present detailed analysis of the areas of significant slip during several recent (last 20 years) large earthquakes in the Mexican subduction zone. The most recent earthquake of 20 March 2012 (Mw7.4) occurred near the Guerrero/Oaxaca border. The slip was concentrated on the plate interface below land and the epicentral PGAs ranged between 0.2 and 0.7g. The updip portion of the plate interface had previously broken during the 25 Feb 1996 earthquake (Mw7.1), which was a slow earthquake and produced anomalously low PGAs (Iglesias et al., 2003). This indicates that in this region the area close to the trench is at least partially locked, with some earthquakes breaking the down-dip portion of the interface and others rupturing the up-dip portion. The Jalisco/Colima segment of the subduction zone seems to behave in a similar fashion. The 9 October 1995 (Mw 8.0) earthquake generated small accelerations relative to its size. The energy to moment ratio, E0/M0, is 4.2e-6 (Pérez-Campos, Singh and Beroza, 2003), a value similar to the Feb, 1996 earthquake. This value is low compared to other thrust events in the region. The earthquake also had the largest (Ms-Mw) disparity along the Mexican subduction zone, 7.4 vs 8.0. The event produced relatively large tsunami. On the contrary, the 3 June 1932 earthquake (Ms8.2, Mw8.0), that is believed to have broken the same segment of the subduction zone, appears to be "normal." Based on the available evidence, it may be concluded that the 1932 event broke a deeper patch of the plate interface relative to the 1995 event. The mode of rupture

  13. Extreme Uplift and Erosion Rates in Eastern Himalayas (Siang-Brahmaputra Basin) Revealed by Detrital (U-Th)/He Termochronology

    NASA Astrophysics Data System (ADS)

    Tibari, B.; Pik, R.; France-Lanord, C.; Carignan, J.; Lave, J.

    2005-12-01

    The distribution of erosion intensity in a major mountain range such as the Himalaya is a fundamental clue to investigate the interaction between climatic, tectonic and erosion processes that govern the morphology and evolution of an orogen. At the first order, the sediment flux measured on the two major rivers - Ganga and Brahmaputra - suggest higher mean denudation rates for the Eastern Himalaya than Western Himalaya (Galy and France-Lanord, 2001). However, the distribution of erosion in the Brahmaputra basin is not uniform and the Namche Barwa area, drained by the Siang-Tsangpo, appears to supply up to 50 % of the total sediment flux of the Brahmaputra (Singh and France-Lanord, 2002). In order to further constrain the relationships between such localized erosion and the associated exhumation rate of basement, we measured (U-Th)/He ages in detrital zircons from river sediments in the Brahmaputra basin. This thermochronological system (Z-He) is particularly interesting for detrital material because: (i) zircon is preserved during weathering and erosion processes, (ii) its closure temperature (150-180°C, Reiners et al., 2004) corresponds to a depth which is close to the surface but deep enough to avoid perturbations by topography variations, and (iii) the error associated to single grain measurement (8-10 %) allows a good definition of population ages. Z-He ages from the Brahmaputra river in Bangladesh range from 0.4 to 77 Ma. 40 % of the zircon population exhibit Z-He ages between 0.4 and 1 Ma defining the major distribution peak centred at 0.5 Ma. These very young ages correspond to extreme denudation rates of 5 to 7 mm/yr. Dispersed Z-He ages from 12 to 77 Ma do not define any population groups, whereas the remaining 40 % of the zircons have ages distributed between 2.5 and 7 Ma, which correspond to the pool of ages recorded by preliminary Z-He ages on the other Himalayan rivers of the basin. Therefore, such very high denudation rates (5-7 mm/yr) seems to

  14. PREFACE: Preface

    NASA Astrophysics Data System (ADS)

    Sathyaprakash, B. S.; Singh, Tejinder

    2014-03-01

    painstaking task of proofreading and copyediting the accepted papers. We also thank the SOC, and the Workshop Chairs for their help in putting together an excellent scientific programme, the LOC for the wonderful organization, and the referees of papers for their help in improving the quality of the papers. Finally, we would like to thank all the authors who have made the publication of these proceedings possible, through their contribution. B S Sathyaprakash and Tejinder P Singh Scientific Organizing Committee Pijushpani Bhattacharjee (SINP, India) J Richard Bond (CITA, Canada) Manuela Campanelli (RIT, USA) Debajyoti Choudhury (Delhi University, India) Richard Ellis (Caltech, USA) Gary Gibbons (DAMTP, UK) Pankaj Joshi (TIFR, India) Romesh Kaul (IMSc, India) Subhabrata Majumdar (TIFR, India) Don Marolf (UCSB, USA) Ramesh Narayan (CfA, Harvard University, USA) Lyman Page (Princeton University, USA) Misao Sasaki (YITP, Japan) B S Sathyaprakash (Cardiff University, UK) Ashoke Sen (HRI, India) Tarun Souradeep (IUCAA, India) [Chair] P S Sreekumar (ISRO, India) Alexei Starobinsky (Landau Institute, Russia) Sumati Surya (RRI, India) C S Unnikrishnan (TIFR, India) Spenta Wadia (TIFR, India) Local Organzing Committee Ghanashyam Date A Gopakumar Subhabrata Majumdar D Narasimha T P Singh (Chair) Supporting Staff V Chellathurai [Scientific Programmes Coordinator] Ashok Deshpande [Accounts Officer] Margaret D'Souza [Secretary] Shobha Jagtap [Secretary] Nishikant Kadam [Secretary] Vijay Kadam [Assistant] A list of participants is available in the PDF

  15. Specific soluble oligomers of amyloid-β peptide undergo replication and form non-fibrillar aggregates in interfacial environments.

    PubMed

    Kumar, Amit; Paslay, Lea C; Lyons, Daniel; Morgan, Sarah E; Correia, John J; Rangachari, Vijayaraghavan

    2012-06-15

    Aggregates of amyloid-β (Aβ) peptides have been implicated in the etiology of Alzheimer disease. Among the different forms of Aβ aggregates, low molecular weight species ranging between ~2- and 50-mers, also called "soluble oligomers," have emerged as the species responsible for early synaptic dysfunction and neuronal loss. Emerging evidence suggests that the neurotoxic oligomers need not be formed along the obligatory nucleation-dependant fibril formation pathway. In our earlier work, we reported the isolation of one such "off-pathway" 12-18-mer species of Aβ42 generated from fatty acids called large fatty acid-derived oligomers (LFAOs) (Kumar, A., Bullard, R. L., Patel, P., Paslay, L. C., Singh, D., Bienkiewicz, E. A., Morgan, S. E., and Rangachari, V. (2011) PLoS One 6, e18759). Here, we report the physiochemical aspects of LFAO-monomer interactions as well as LFAO-LFAO associations in the presence of interfaces. We discovered that LFAOs are a replicating strain of oligomers that recruit Aβ42 monomers and quantitatively convert them into LFAO assemblies at the expense of fibrils, a mechanism similar to prion propagation. We also found that in the presence of hexane-buffer or chloroform-buffer interfaces LFAOs are able to associate with themselves to form larger but non-fibrillar aggregates. These results further support the hypothesis that low molecular weight oligomers can be generated via non-fibril formation pathways. Furthermore, the unique replicating property of off-pathway oligomers may hold profound significance for Alzheimer disease pathology.

  16. To Study the Incidence, Predictive Factors and Clinical Outcome of Spontaneous Bacterial Peritonitis in Patients of Cirrhosis with Ascites

    PubMed Central

    Kaur, Jasmine; Kazal, Harbans Lal

    2015-01-01

    Objective To study the prevalence and predictive factors of spontaneous bacterial peritonitis (SBP) in patients of cirrhosis with ascites and to study the clinical characteristics and prognosis of patients with SBP. Materials and Methods The present study was conducted on 122 cases admitted in Department of Medicine, through emergency, in Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India. Cases of cirrhosis (irrespective of aetiology) with ascites between the ages of 18-75 years were included in this study. Ascitic fluid of every patient was aspirated under all aseptic measures, before initiation of antibiotic therapy and was sent for biochemical analysis, culture and cytological analysis. Results Mean age of patients enrolled was 50.30± 10.98 years. 85% were male and 15% were female. Alcohol (73.8%) was the leading cause of cirrhosis followed by HCV (37.7%) and HBV (4.9%). Of the 122 patients studied, 27 (20.4%) patients were diagnosed as having SBP and its variants. Monomicrobial Bacterascites (BA) was present in 5 patients and Culture Negative Neutrocytic Ascites (CNNA) was present in 22 patients. Escherichia coli were the most common isolated organism followed by Klebsiella. The various factors that predispose to development of SBP include low ascitic fluid protein concentration, a high level of serum bilirubin, deranged serum creatinine, high Child-Pugh score and high MELD score. Conclusion Ascitic fluid analysis remains the single most important test for identifying and assessing a course of SBP. Bedside inoculation of 10-20ml of ascitic fluid into culture bottle at patient bedside will yield better results. Early diagnosis and treatment will reduce the mortality rate in these patients. PMID:26393155

  17. On the pre-perihelion temporal activity of comet 9P/Tempel 1 during the favorable apparition of 2005

    NASA Astrophysics Data System (ADS)

    de Almeida, A.; Serrano, G.; Sanzovo, G.; Trevisan Sanzovo, D.

    2014-07-01

    The short-period (5.5 years) comet 9P/Tempel 1 was revisited by NASA's Stardust-NExT probe in 2011 February 15, in a flyby at a distance of only about 181 km. This is the first time a comet is visited twice by two different probes (the first visit in 2005 July 4, by NASA's Deep Impact probe). Tempel 1 is not a bright or very active comet. The brightest apparent magnitude in 25 appearances, since the discovery (1867), has been m=9.5, well below the limit of visibility to the naked eye. Here, we study the temporal activity, based on 495 apparent visual magnitude estimates (ICQ), obtained during the very favorable apparition of 2005 (the comet passed at 0.71 au from the Earth in 2005 May 3) by the Semi-Empirical Method of Visual Magnitudes (SEMVM, de Almeida, Singh&Huebner, 1997). We determine a model dependent activity at the time immediately before the Deep Impact (4 July 2005 at 5:52 UTC) in fairly good agreement with Schleicher et al. (2006), Feaga et al. (2007) and Gicquel et al. (2012) from the Spitzer spacecraft observations, and a day later, at the time of the perihelion passage (5 July 2005 at 5:31 UTC), also in good agreement with Biver et al. (2007) and Farnham et al. (2010), most likely powered by water-ice sublimation. Our results are consistent, for an active area of 10% and a minimum nuclear radius of 2.5 km , with the radio OH observations in 18-cm (Howell et al., 2007; Biver et al., 2007), and the H_2O observations by satellites SWAN (Mäkinen et al., 2007; Bensch et al., 2007) and Odin (Biver et al., 2007), in the pre-perihelion phase.

  18. Boson peak in supercooled liquids: Time domain observations and mode coupling theory

    NASA Astrophysics Data System (ADS)

    Cang, Hu; Li, Jie; Andersen, Hans C.; Fayer, M. D.

    2005-08-01

    Optical heterodyne-detected optical Kerr effect (OHD-OKE) experiments are presented for the supercooled liquid acetylsalicylic acid (aspirin - ASP). The ASP data and previously published OHD-OKE data on supercooled dibutylphthalate (DBP) display highly damped oscillations with a periods of ˜2ps as the temperature is reduced to and below the mode coupling theory (MCT) temperature TC. The oscillations become more pronounced below TC. The oscillations can be interpreted as the time domain signature of the boson peak. Recently a schematic MCT model, the Sjögren model, was used to describe the OHD-OKE data for a number of supercooled liquids by Götze and Sperl [W. Götze and M. Sperl, Phys. Rev. E 92, 105701 (2004)], but the short-time and low-temperature behaviors were not addressed. Franosch et al. [T. Franosch, W. Gotze, M. R. Mayr, and A. P. Singh, Phys. Rev. E 55, 3183 (1997)] found that the Sjögren model could describe the boson peak observed by depolarized light-scattering (DLS) experiments on glycerol. The OHD-OKE experiment measures a susceptibility that is a time domain equivalent of the spectrum measured in DLS. Here we present a detailed analysis of the ASP and DBP data over a broad range of times and temperatures using the Sjögren model. The MCT schematic model is able to describe the data very well at all temperatures and relevant time scales. The trajectory of MCT parameters that fit the high-temperature data (no short-time oscillations) when continued below TC results in calculations that reproduce the oscillations seen in the data. The results indicate that increasing translational-rotational coupling is responsible for the appearance of the boson peak as the temperature approaches and drops below TC.

  19. Hydrogen-bond acidity of OH groups in various molecular environments (phenols, alcohols, steroid derivatives, and amino acids structures): experimental measurements and density functional theory calculations.

    PubMed

    Graton, Jérôme; Besseau, François; Brossard, Anne-Marie; Charpentier, Eloïse; Deroche, Arnaud; Le Questel, Jean-Yves

    2013-12-12

    The hydrogen-bond (H-bond) donating strengths of a series of 36 hydroxylic H-bond donors (HBDs) with N-methylpyrrolidinone have been measured in CCl4 solution by FTIR spectrometry. These data allow the definition of a H-bond acidity scale named pKAHY covering almost three pK units, corresponding to 16 kJ mol(-1). These results are supplemented by equilibrium constants determined in CH2Cl2 for one-third of the data set to study compounds showing a poor solubility in CCl4. A systematic comparison of these experimental results with theoretical data computed in the gas phase using DFT (density functional theory) calculations has also been carried out. Quantum electrostatic parameters appear to accurately describe the H-bond acidity of the hydroxyl group, whereas partial atomic charges according to the Merz-Singh-Kollman and CHelpG schemes are not suitable for this purpose. A substantial decrease of the H-bond acidity of the OH group is pointed out when the hydroxyl moiety is involved in intramolecular H-bond interactions. In such situations, the interactions are further characterized through AIM and NBO analyses, which respectively allow localizing the corresponding bond critical point and the quantification of a significant charge transfer from the available lone pair to the σ*OH antibonding orbital. Eventually, the H-bond ability of the hydroxyl groups of steroid derivatives and of lateral chains of amino acids are evaluated on the basis of experimental and/or theoretical data.

  20. Factors predicting Behavior Management Problems during Initial Dental Examination in Children Aged 2 to 8 Years

    PubMed Central

    Kumar, Dipanshu; Anand, Ashish; Mittal, Vipula; Singh, Aparna; Aggarwal, Nidhi

    2017-01-01

    Aim The aim of the present study was to identify the various background variables and its influence on behavior management problems (BMP) in children. Materials and methods The study included 165 children aged 2 to 8 years. During the initial dental visit, an experienced operator obtained each child’s background variables from accompanying guardians using a standardized questionnaire. Children’s dental behavior was rated by Frankel behavior rating scale. The behavior was then analyzed in relation to the answers of the questionnaire, and a logistic regression model was used to determine the power of the variables, separately or combined, to predict BMP. Results The logistic regression analysis considering differences in background variables between children with negative or positive behavior. Four variables turned out to be as predictors: Age, the guardian’s expectation of the child’s behavior at the dental examination, the child’s anxiety when meeting unfamiliar people, and the presence and absence of toothache. Conclusion The present study concluded that by means of simple questionnaire BMP in children may be expected if one of these attributes is found. Clinical significance Information on the origin of dental fear and uncooperative behavior in a child patient prior to treatment process may help the pediatric dentist plan appropriate behavior management and treatment strategy. How to cite this article Sharma A, Kumar D, Anand A, Mittal V, Singh A, Aggarwal N. Factors predicting Behavior Management Problems during Initial Dental Examination in Children Aged 2 to 8 Years. Int J Clin Pediatr Dent 2017;10(1):5-9. PMID:28377646

  1. Thin layer drying of tomato slices.

    PubMed

    Das Purkayastha, Manashi; Nath, Amit; Deka, Bidyut Chandra; Mahanta, Charu Lata

    2013-08-01

    The hot air convective drying characteristics of blanched tomato (Lycopersicon esculantum L.) slices have been investigated. Drying experiments were carried out at four different temperatures (50, 60, 65 and 70 °C). The effect of drying temperatures on the drying behavior of the tomato slices was evaluated. All drying experiments had only falling rate period. The average effective diffusivity values varied from 0.5453 × 10(-9) to 2.3871 × 10(-9) m(2)/s over the temperature range studied and the activation energy was estimated to be 61.004 kJ/mol. In order to select a suitable form of the drying curve, six different thin layer drying models (Henderson-Pabis, Page, Diamante et al., Wang and Singh, Logarithmic and Newton models) were fitted to the experimental data. The goodness of fit tests indicated that the Logarithmic model gave the best fit to experimental results, which was closely followed by the Henderson-Pabis model. The influence of varied drying temperatures on quality attributes of the tomato slices viz. Hunter color parameters, ascorbic acid, lycopene, titratable acidity, total sugars, reducing sugars and sugar/acid ratio of dried slices was also studied. Slices dried at 50 and 60 °C had high amount of total sugars, lycopene, sugar/acid ratio, Hunter L- and a-values. Drying of slices at 50 °C revealed optimum retention of ascorbic acid, sugar/acid ratio and red hue, whereas, drying at higher temperature (65 and 70 °C) resulted in a considerable decrease in nutrients and colour quality of the slices.

  2. Fenton treatment of landfill leachate under different COD loading factors.

    PubMed

    Singh, Shrawan K; Tang, Walter Z; Tachiev, Georgio

    2013-10-01

    The application of Fenton treatment technology for treatment of landfill leachate greatly depends on the optimum Fenton operating conditions for a specific leachate. Determining optimum Fenton conditions requires multiple experiments using variable reaction parameters (pH, temperature, and H2O2 and Fe(2+) doses) and previous researches show a wide range of optimal operating conditions. In this study, the applicability of the dimensionless loading factor (LCOD), which is defined as the initial COD (COD0) of leachate with respect to available O2 for oxidation, was examined to derive optimum Fenton oxidant dose using reduced set of experiments. The Fenton experiments were conducted using leachates with three different COD0 concentrations, 1092, 546, and 273mgL(-1), LCOD in the range of 0.25-1.0, and H2O2/Fe(2+) 1.8 (w/w). The experimental data were analyzed to determine the correlation between the LCOD factor and selected feasibility parameters, amongst which were: (i) the COD removal kinetics, (ii) the total COD removal, (iii) the usability of H2O2 with respect to COD removal, (iv) leachate biodegradability, and (v) treatment cost incurred by chemical usage. The experimental COD removal with respect to the amount of O2 supplied by H2O2 was compared with respect to the optimum COD removal efficiency by the equation: η(FP(optimum)=0.733L(COD)-0.182 as developed by Singh and Tang (2013) and a LCOD of 0.75 was determined to be the optimum L(COD) for leachate treatment.

  3. SU-E-I-43: Pediatric CT Dose and Image Quality Optimization

    SciTech Connect

    Stevens, G; Singh, R

    2014-06-01

    Purpose: To design an approach to optimize radiation dose and image quality for pediatric CT imaging, and to evaluate expected performance. Methods: A methodology was designed to quantify relative image quality as a function of CT image acquisition parameters. Image contrast and image noise were used to indicate expected conspicuity of objects, and a wide-cone system was used to minimize scan time for motion avoidance. A decision framework was designed to select acquisition parameters as a weighted combination of image quality and dose. Phantom tests were used to acquire images at multiple techniques to demonstrate expected contrast, noise and dose. Anthropomorphic phantoms with contrast inserts were imaged on a 160mm CT system with tube voltage capabilities as low as 70kVp. Previously acquired clinical images were used in conjunction with simulation tools to emulate images at different tube voltages and currents to assess human observer preferences. Results: Examination of image contrast, noise, dose and tube/generator capabilities indicates a clinical task and object-size dependent optimization. Phantom experiments confirm that system modeling can be used to achieve the desired image quality and noise performance. Observer studies indicate that clinical utilization of this optimization requires a modified approach to achieve the desired performance. Conclusion: This work indicates the potential to optimize radiation dose and image quality for pediatric CT imaging. In addition, the methodology can be used in an automated parameter selection feature that can suggest techniques given a limited number of user inputs. G Stevens and R Singh are employees of GE Healthcare.

  4. Protein Expression in Insect and Mammalian Cells Using Baculoviruses in Wave Bioreactors.

    PubMed

    Kadwell, Sue H; Overton, Laurie K

    2016-01-01

    Many types of disposable bioreactors for protein expression in insect and mammalian cells are now available. They differ in design, capacity, and sensor options, with many selections available for either rocking platform, orbitally shaken, pneumatically mixed, or stirred-tank bioreactors lined with an integral disposable bag (Shukla and Gottschalk, Trends Biotechnol 31(3):147-154, 2013). WAVE Bioreactors™ were among the first disposable systems to be developed (Singh, Cytotechnology 30:149-158, 1999). Since their commercialization in 1999, Wave Bioreactors have become routinely used in many laboratories due to their ease of operation, limited utility requirements, and protein expression levels comparability to traditional stirred-tank bioreactors. Wave Bioreactors are designed to use a presterilized Cellbag™, which is attached to a rocking platform and inflated with filtered air provided by the bioreactor unit. The Cellbag can be filled with medium and cells and maintained at a set temperature. The rocking motion, which is adjusted through angle and rock speed settings, provides mixing of oxygen (and CO2, which is used to control pH in mammalian cell cultures) from the headspace created in the inflated Cellbag with the cell culture medium and cells. This rocking motion can be adjusted to prevent cell shear damage. Dissolved oxygen and pH can be monitored during scale-up, and samples can be easily removed to monitor other parameters. Insect and mammalian cells grow very well in Wave Bioreactors (Shukla and Gottschalk, Trends Biotechnol 31(3):147-154, 2013). Combining Wave Bioreactor cell growth capabilities with recombinant baculoviruses engineered for insect or mammalian cell expression has proven to be a powerful tool for rapid production of a wide range of proteins.

  5. Computational fluid dynamics modeling of laboratory flames and an industrial flare.

    PubMed

    Singh, Kanwar Devesh; Gangadharan, Preeti; Chen, Daniel H; Lou, Helen H; Li, Xianchang; Richmond, Peyton

    2014-11-01

    A computational fluid dynamics (CFD) methodology for simulating the combustion process has been validated with experimental results. Three different types of experimental setups were used to validate the CFD model. These setups include an industrial-scale flare setups and two lab-scale flames. The CFD study also involved three different fuels: C3H6/CH/Air/N2, C2H4/O2/Ar and CH4/Air. In the first setup, flare efficiency data from the Texas Commission on Environmental Quality (TCEQ) 2010 field tests were used to validate the CFD model. In the second setup, a McKenna burner with flat flames was simulated. Temperature and mass fractions of important species were compared with the experimental data. Finally, results of an experimental study done at Sandia National Laboratories to generate a lifted jet flame were used for the purpose of validation. The reduced 50 species mechanism, LU 1.1, the realizable k-epsilon turbulence model, and the EDC turbulence-chemistry interaction model were usedfor this work. Flare efficiency, axial profiles of temperature, and mass fractions of various intermediate species obtained in the simulation were compared with experimental data and a good agreement between the profiles was clearly observed. In particular the simulation match with the TCEQ 2010 flare tests has been significantly improved (within 5% of the data) compared to the results reported by Singh et al. in 2012. Validation of the speciated flat flame data supports the view that flares can be a primary source offormaldehyde emission.

  6. Correlation of Streptococcus mutans count in Mother-child Pair of Working and Nonworking Mothers: A Cross-sectional Study

    PubMed Central

    Goswami, Mousumi; Singh, Darrel; Massod, Shahid S; Nganba, Khundrakpam

    2016-01-01

    Purpose To determine the prevalence of Streptococcus mutans (MS) in mother-child pairs and to evaluate the correlation in the levels of salivary MS of working and nonworking mothers with that of their children and their associations with other related factors. Materials and methods A cross-sectional study was carried out among 100 mother-child pairs residing in New Multan Nagar Colony, New Delhi, India. A total of 50 children with their mothers were included in the working group and another 50 were included in the nonworking group. A questionnaire regarding the feeding habits, oral hygiene habits, daily intake of sugars of the children along with their weaning time was carried out. All mothers and children were clinically examined for recording decayed, extracted, and filled teeth (deft)/decayed, missing, and filled teeth (DMFT), and whole unstimulated saliva was collected and cultured for MS in the laboratory. The data were collected and subjected to statistical analysis using chi-square, Spearman’s correlation, and logistic regression analysis. Results The prevalence of salivary MS in the children was 69%. A statistically significant correlation was found between the oral levels of MS in nonworking and working mother-child pairs. Regression analysis showed that those children who feed by bottle for more than 12 months, have daily sweet intake, have sugars in feeding bottle and have higher defts were more likely to have mutans score of 1 or 2. Conclusion The mother, working or nonworking, being the primary care provider is the major source of transmission of MS to their child irrespective of the amount of time spent with them. How to cite this article Sharma P, Goswami M, Singh D, Massod SS, Nganba K. Correlation of Streptococcus mutans count in Mother-child Pair of Working and Nonworking Mothers: A Cross-sectional Study. Int J Clin Pediatr Dent 2016;9(4):342-348. PMID:28127167

  7. Evidence for a link between histone deacetylation and Ca²+ homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts.

    PubMed

    Ihlefeld, Katja; Claas, Ralf Frederik; Koch, Alexander; Pfeilschifter, Josef M; Meyer Zu Heringdorf, Dagmar

    2012-11-01

    Embryonic fibroblasts from S1P (sphingosine-1-phosphate) lyase-deficient mice [Sgpl1-/- MEFs (mouse embryonic fibroblasts)] are characterized by intracellular accumulation of S1P, elevated cytosolic [Ca2+]i and enhanced Ca2+ storage. Since S1P, produced by sphingosine kinase 2 in the nucleus of MCF-7 cells, inhibited HDACs (histone deacetylases) [Hait, Allegood, Maceyka, Strub, Harikumar, Singh, Luo, Marmorstein, Kordula, Milstein et al. (2009) Science 325, 1254-1257], in the present study we analysed whether S1P accumulated in the nuclei of S1P lyase-deficient MEFs and caused HDAC inhibition. Interestingly, nuclear concentrations of S1P were disproportionally elevated in Sgpl1-/- MEFs. HDAC activity was reduced, acetylation of histone 3-Lys9 was increased and the HDAC-regulated gene p21 cyclin-dependent kinase inhibitor was up-regulated in these cells. Furthermore, the expression of HDAC1 and HDAC3 was reduced in Sgpl1-/- MEFs. In wild-type MEFs, acetylation of histone 3-Lys9 was increased by the S1P lyase inhibitor 4-deoxypyridoxine. The non-specific HDAC inhibitor trichostatin A elevated basal [Ca2+]i and enhanced Ca2+ storage, whereas the HDAC1/2/3 inhibitor MGCD0103 elevated basal [Ca2+]i without influence on Ca2+ storage in wild-type MEFs. Overexpression of HDAC1 or HDAC2 reduced the elevated basal [Ca2+]i in Sgpl1-/- MEFs. Taken together, S1P lyase-deficiency was associated with elevated nuclear S1P levels, reduced HDAC activity and down-regulation of HDAC isoenzymes. The decreased HDAC activity in turn contributed to the dysregulation of Ca2+ homoeostasis, particularly to the elevated basal [Ca2+]i, in Sgpl1-/- MEFs.

  8. Growth, tolerance efficiency and phytoremediation potential of Ricinus communis (L.) and Brassica juncea (L.) in salinity and drought affected cadmium contaminated soil.

    PubMed

    Bauddh, Kuldeep; Singh, Rana P

    2012-11-01

    We have previously reported that Ricinus communis (castor) is more tolerant to soil cadmium (Cd) and more efficient for Cd phytoremediation than Brassica juncea (Indian mustard) (Bauddh and Singh, 2012). In the present study, R. communis was found more tolerant to salinity and drought in presence of Cd and removed more Cd in a given time than Indian mustard. R. communis produced 23 and twelve folds higher biomass in terms of fresh weight and dry weight, respectively than that in B. juncea during three months when grown in Cd contaminated soil in presence of 100mM NaCl salinity and ten day water withdrawal based drought at 90 day after sowing (DAS). Castor plants showed stronger self-protection ability in form of proline bioaccumulation (r(2)=0.949) than Indian mustard (r(2)=0.932), whereas a lower r(2) for malondialdehyde (MDA) and total soluble protein in R. communis (r(2)=0.914 and r(2)=0.915, respectively) than that of B. juncea (r(2)=0.947 and r(2)=0.927, respectively) indicated a greater damage to cell membrane in Indian mustard during the multiple stress conditions. Though, the amount of Cd accumulated in the roots and shoots of Indian mustard was higher as per unit biomass than that in castor, total removal of the metal from soil was much higher in castor on per plant basis in the same period in presence of the stresses. R. communis accumulated about seventeen and 1.5 fold higher Cd in their roots and shoots, respectively than that of B. juncea in 90 DAS under the multiple stresses. Salinity alone enhanced Cd uptake, whereas drought stress reduced its uptake in both the plants.

  9. Application of a PK-PD Modeling and Simulation-Based Strategy for Clinical Translation of Antibody-Drug Conjugates: a Case Study with Trastuzumab Emtansine (T-DM1).

    PubMed

    Singh, Aman P; Shah, Dhaval K

    2017-04-03

    Successful clinical translation of antibody-drug conjugates (ADCs) can be challenging due to complex pharmacokinetics and differences between preclinical and clinical tumors. To facilitate this translation, we have developed a general pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation (M&S)-based strategy for ADCs. Here we present the validation of this strategy using T-DM1 as a case study. A previously developed preclinical tumor disposition model for T-DM1 (Singh and Shah, AAPSJ. 2015; 18(4):861-875) was used to develop a PK-PD model that can characterize in vivo efficacy of T-DM1 in preclinical tumor models. The preclinical data was used to estimate the efficacy parameters for T-DM1. Human PK of T-DM1 was a priori predicted using allometric scaling of monkey PK parameters. The predicted human PK, preclinically estimated efficacy parameters, and clinically observed volume and growth parameters for breast cancer were combined to develop a translated clinical PK-PD model for T-DM1. Clinical trial simulations were performed using the translated PK-PD model to predict progression-free survival (PFS) and objective response rates (ORRs) for T-DM1. The model simulated PFS rates for HER2 1+ and 3+ populations were comparable to the rates observed in three different clinical trials. The model predicted only a modest improvement in ORR with an increase in clinically approved dose of T-DM1. However, the model suggested that a fractionated dosing regimen (e.g., front loading) may provide an improvement in the efficacy. In general, the PK-PD M&S-based strategy presented here is capable of a priori predicting the clinical efficacy of ADCs, and this strategy has been now retrospectively validated for all clinically approved ADCs.

  10. Evaluation of therapeutic effects of natural killer (NK) cell-based immunotherapy in mice using in vivo apoptosis bioimaging with a caspase-3 sensor.

    PubMed

    Lee, Ho Won; Singh, Thoudam Debraj; Lee, Sang-Woo; Ha, Jeoung-Hee; Rehemtulla, Alnawaz; Ahn, Byeong-Cheol; Jeon, Young Hyun; Lee, Jaetae

    2014-07-01

    Natural killer (NK) cell-based immunotherapy is a promising strategy for cancer treatment, and caspase-3 is an important effector molecule in NK cell-mediated apoptosis in cancers. Here, we evaluated the antitumor effects of NK cell-based immunotherapy by serial noninvasive imaging of apoptosis using a caspase-3 sensor in mice with human glioma xenografts. Human glioma cells expressing both a caspase-3 sensor as a surrogate marker for caspase-3 activation and Renilla luciferase (Rluc) as a surrogate marker for cell viability were established and referred to as D54-CR cells. Human NK92 cells were used as effector cells. Treatment with NK92 cells resulted in a time- and effector number-dependent increase in bioluminescence imaging (BLI) activity of the caspase-3 sensor in D54-CR cells in vitro. Caspase-3 activation by NK92 treatment was blocked by Z-VAD treatment in D54-CR cells. Transfusion of NK92 cells induced an increase of the BLI signal by caspase-3 activation in a dose- and time-dependent manner in D54-CR tumor-bearing mice but not in PBS-treated mice. Accordingly, sequential BLI with the Rluc reporter gene revealed marked retardation of tumor growth in the NK92-treatment group but not in the PBS-treatment group. These data suggest that noninvasive imaging of apoptosis with a caspase-3 sensor can be used as an effective tool for evaluation of therapeutic efficacy as well as for optimization of NK cell-based immunotherapy.-Lee, H. W., Singh, T. D., Lee, S.-W., Ha, J.-H., Rehemtulla, A., Ahn, B.-C., Jeon, Y.-H., Lee, J. Evaluation of therapeutic effects of natural killer (NK) cell-based immunotherapy in mice using in vivo apoptosis bioimaging with a caspase-3 sensor.

  11. Variability in Proline-Accumulating Ability of Barley (Hordeum vulgare L.) Cultivars Induced by Vapor Pressure Deficit.

    PubMed

    Naidu, B P; Aspinall, D; Paleg, L G

    1992-02-01

    This work was undertaken in an effort to reconcile the conflicting proline-accumulating responses of the barley (Hordeum vulgare L.) cultivars, Excelsior and Proctor, reported by Singh et al. (1972) and Hanson et al. (1976). It deals with the effects of different vapor pressure deficits (VPD) during growth and subsequent drought stress on several barley cultivars. A higher VPD (1.2 kilopascals) during Clipper seedling growth resulted in higher solute-accumulating ability, seemingly independently of leaf water potential, than a lower VPD (0.12 kilopascals). The higher VPD during stress also resulted in higher solute contents, and this response may be more closely related to leaf water potential. When the responses of Excelsior and Proctor were examined in detail, it was found that the relative proline-accumulating ability of the two cultivars was dependent upon the VPD under which they were grown. At low VPD, Proctor accumulated significantly more proline than did Excelsior; whereas at higher VPD, Excelsior accumulated more proline than did Proctor. The crossover occurred at a VPD of about 0.72 kilopascals. This reversal of cultivar response was enhanced by multiplying seed under the two VPD extremes. Glycinebetaine accumulation did not demonstrate the crossover effect, although the concentration of this compound in all cultivars also depended on the VPD prevailing during growth and/or stress. Solute levels, in general, were more closely related to the decrease in relative water content than to a decrease in leaf water potential. It is concluded that the conflicting proline-accumulating responses of Excelsior and Proctor could be explained by these findings.

  12. Incremental shuttle walk test: Reference values and predictive equation for healthy Indian adults

    PubMed Central

    Agarwal, Bela; Shah, Monal; Andhare, Nilesh; Mullerpatan, Rajani

    2016-01-01

    Purpose: Physical inactivity in Indians is leading to an increase in noncommunicable disorders at an early age in life. Early identification and quantification of the lack of physical activity using simple and reliable exercise testing is the need of the hour. The incremental shuttle walk test (ISWT) is an externally paced walk test widely used for the evaluation of exercise capacity. Currently the normative values available for clinical reference are generated from Western populations. Hence, the study was conducted to find normative values for the ISWT in healthy Indian adults (17-75 years). Materials and Methods: A convenience sample of 862 subjects was recruited after ethical approval was obtained. All subjects were divided into groups as per age and gender. For age, the grouping was as follows: Group 1: Young adulthood (17-40 years), group 2: Middle adulthood (40-65 years), and group 3: Old adulthood (>65 years). The ISWT was performed as per standard protocol by Sally Singh. Results: The average distance walked were 709.2m,556.4m and 441.3m in females and 807.9 m, 639.6 m and 478.2 m in males in the three respective age groups. Stepwise regression analysis revealed age and gender as key variables correlating with incremental shuttle walk distance (ISWD). The derived predictive equations for males and females may be given as follows: 740.351 - (5.676 × age) + (99.007 × gender). Conclusion: Reference values were generated for healthy Indian adults. Physiological response to the ISWT was shown to be affected by gender and increasing age. Easily measurable variables explained 68% of the variance seen in the test, making the reference equation a relevant part of the evaluation of the ISWT. PMID:26933305

  13. Digit ratio (2D:4D), salivary testosterone, and handedness.

    PubMed

    Beaton, Alan A; Rudling, Nick; Kissling, Christian; Taurines, Regine; Thome, Johannes

    2011-03-01

    The length of the index finger relative to that of the ring finger, the 2D:4D ratio, has been taken to be a marker of the amount of testosterone (T) that was present in the foetal environment (Manning, Scutt, Wilson, & Lewis-Jones, 1998). It has also been suggested (Geschwind & Galaburda, 1987) that elevated levels of foetal T are associated with left-handedness and that adult levels of circulating T might relate to foetal levels (Jamison, Meier, & Campbell, 1993). We used multiple regression analyses to investigate whether there is any relationship between either left or right hand 2D:4D ratio and handedness. We also examined whether adult levels of salivary T (or cortisol, used as a control hormone) predict digit ratio and/or handedness. Although the 2D:4D ratio of neither the left nor the right hand was related to handedness, the difference between the digit ratios of the right and left hands, D(R-L), was a significant predictor of handedness and of the performance difference between the hands on a peg-moving task, supporting previous findings (Manning & Peters, 2009; Manning et al., 1998; Manning, Trivers, Thornhill, & Singh, 2000; Stoyanov, Marinov, & Pashalieva, 2009). Adult circulating T levels did not predict the digit ratio of the left or right hand; nor was there a significant relationship between concentrations of salivary T (or cortisol) and either hand preference or asymmetry in manual skill. We suggest that the association between D(R-L) and hand preference arises because D(R-L) is a correlate of sensitivity to T in the developing foetus.

  14. Mens' attitudes about abortion in Uganda.

    PubMed

    Moore, Ann M; Jagwe-Wadda, Gabriel; Bankole, Akinrinola

    2011-01-01

    Abortion is illegal in Uganda except to save the life of the woman. Nevertheless, the practice is quite common: about 300,000 induced abortions occur annually among Ugandan women aged 15-49 (Singh et al., 2005) and a large proportion of these women require treatment for post-abortion complications. In the male-dominant culture of Uganda, where men control most of the financial resources, men play a critical part in determining whether women receive a safe abortion, or appropriate treatment if they experience abortion complications. This study examines men's roles in determining women's access to a safer abortion and post-abortion care. It draws on in-depth interviews carried out in 2003 with 61 women aged 18-60 and 21 men aged 20-50 from Kampala and Mbarara, Uganda. Respondents' descriptions of men's involvement in women's abortion care agreed that men's stated attitudes about abortion often prevented women from involving them in either the abortion or post-abortion care. Most men believe that if a woman is having an abortion, it must be because she is pregnant with another man's child, although this does not correspond with women's reasons for having an abortion--a critical disjuncture revealed by the data between men's perceptions of, and women's realities regarding, reasons for seeking an abortion. If the woman does experience post-abortion complications, the prevailing attitude among men in the sample was that they cannot support a woman in such a situation seeking care because if it had been his child, she would not have had a covert abortion. Since money is critical to accessing appropriate care, without men's support, women seeking an abortion may not be able to access safer abortion options and if they experience complications, they may delay care-seeking or may not obtain care at all. Barriers to involving men in abortion decision-making endanger women's health and possibly their lives.

  15. Identification of hydrological model parameters for flood forecasting using data depth measures

    NASA Astrophysics Data System (ADS)

    Krauße, T.; Cullmann, J.

    2011-03-01

    The development of methods for estimating the parameters of hydrological models considering uncertainties has been of high interest in hydrological research over the last years. Besides the very popular Markov Chain Monte Carlo (MCMC) methods which estimate the uncertainty of model parameters in the settings of a Bayesian framework, the development of depth based sampling methods, also entitled robust parameter estimation (ROPE), have attracted an increasing research interest. These methods understand the estimation of model parameters as a geometric search of a set of robust performing parameter vectors by application of the concept of data depth. Recent studies showed that the parameter vectors estimated by depth based sampling perform more robust in validation. One major advantage of this kind of approach over the MCMC methods is that the formulation of a likelihood function within a Bayesian uncertainty framework gets obsolete and arbitrary purpose-oriented performance criteria defined by the user can be integrated without any further complications. In this paper we present an advanced ROPE method entitled the Advanced Robust Parameter Estimation by Monte Carlo algorithm (AROPEMC). The AROPEMC algorithm is a modified version of the original robust parameter estimation algorithm ROPEMC developed by Bárdossy and Singh (2008). AROPEMC performs by merging iterative Monte Carlo simulations, identifying well performing parameter vectors, the sampling of robust parameter vectors according to the principle of data depth and the application of a well-founded stopping criterion applied in supervised machine learning. The principals of the algorithm are illustrated by means of the Rosenbrock's and Rastrigin's function, two well known performance benchmarks for optimisation algorithms. Two case studies demonstrate the advantage of AROPEMC compared to state of the art global optimisation algorithms. A distributed process-oriented hydrological model is calibrated and

  16. Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene.

    PubMed

    Singh, Abanish; Babyak, Michael A; Brummett, Beverly H; Jiang, Rong; Watkins, Lana L; Barefoot, John C; Kraus, William E; Shah, Svati H; Siegler, Ilene C; Hauser, Elizabeth R; Williams, Redford B

    2015-09-01

    Chronic psychosocial stress adversely affects health and is associated with the development of disease [Williams, 2008]. Systematic epidemiological and genetic studies are needed to uncover genetic variants that interact with stress to modify metabolic responses across the life cycle that are the proximal contributors to the development of cardiovascular disease and precipitation of acute clinical events. Among the central challenges in the field are to perform and replicate gene-by-environment (G × E) studies. The challenge of measurement of individual experience of psychosocial stress is magnified in this context. Although many research datasets exist that contain genotyping and disease-related data, measures of psychosocial stress are often either absent or vary substantially across studies. In this paper, we provide an algorithm to create a synthetic measure of chronic psychosocial stress across multiple datasets, applying a consistent criterion that uses proxy indicators of stress components. We validated the computed scores of chronic psychosocial stress by observing moderately strong and significant correlations with the self-rated chronic psychosocial stress in the Multi-Ethnic Study of Atherosclerosis Cohort (Rho = 0.23, P < 0.0001) and with the measures of depressive symptoms in five datasets (Rho = 0.15-0.42, Ps = 0.005 to <0.0001) and by comparing the distributions of the self-rated and computed measures. Finally, we demonstrate the utility of this computed chronic psychosocial stress variable by providing three additional replications of our previous finding of gene-by-stress interaction with central obesity traits [Singh et al., 2015].

  17. Theoretical assessment on mixing properties of liquid Tl-Na alloys

    NASA Astrophysics Data System (ADS)

    Jha, I. S.; Khadka, R.; Koirala, R. P.; Singh, B. P.; Adhikari, D.

    2016-06-01

    Thermodynamic and structural properties of mixing of molten Tl-Na alloys at 673 K have been investigated using quasi-chemical model. To understand the mixing behaviour in more detail, emphasis is placed on the role of interaction energy term, and viscosity and surface tension of the alloys have also been analysed under statistical considerations. Our study shows negative deviation from the Raoultian behaviour in the properties of Tl-Na alloy thereby indicating hetero-coordination in the Tl-Na melt at 673 K in the full range of concentration. Theoretically, computed thermodynamic data at 673 K agree very well with the corresponding experimental data. The viscosities of the alloys computed from Kaptay equation show small negative deviation and those computed from Singh and Sommer's formulation show small positive deviation from ideal values while the Budai-Benko-Kaptay equation predicts noticeable negative deviation in Na-rich end and positive deviation in Tl-rich end of the composition. The calculations of surface tension reveal that results obtained from layered structure approach and compound formation model are in good agreement in the Na-rich side and in reasonable agreement in Tl-rich side of the composition, while those computed from Butler equation show noticeable deviations in the intermediate compositions. Both the viscosity and surface tension of liquid Tl-Na alloys increase with addition of Tl-component, viscosity having approximately linear variation with concentration. The study shows that there is non-linear variation in surface composition with bulk concentration and for most of the compositions the surface of the alloy is enriched with Na-atoms which segregate to the surface.

  18. The CN-radical and OH-parent production rates in comet C/1977 R1 (Kohler)

    NASA Astrophysics Data System (ADS)

    de Almeida, A.; de Freitas Pacheco, J.; Codina Landaberry, S.; Serrano, G.

    2014-07-01

    The present work aims at obtaining information on the overall activity of the bright and extremely long-period (over 100,000 years with a nearly parabolic orbit) comet 1977m = 1977 XIV = C/1977 R1 (Kohler). The comet was observed with an Optical Multichannel Analyzer (OMA) of 500 channels, attached to the 0.61-m Boller & Chivens telescope at the Abrahão de Moraes Observatory of the University of São Paulo in Valinhos (SP, Brazil).The spectral region sscanned was in the interval 3555 Å to 4140 Å, where the intense CN (0,0) band was detected. The continuum was very weak suggesting a low dust-to-gas ratio. From the 8.56 × 10^{-11} erg cm^{-2} s^{-1} total observed flux corrected for atmospheric extinction of the CN (0,0) spectrum, a total number and a production rate of CN molecules in the coma was computed as 1.8 × 10^{31} and 7.8 × 10^{25} molecules s^{-1}, respectively. We also have deduced, semi-empirically (de Almeida, Singh & Huebner 1997), the OH-parent (presumably H_2O) production rates from the photometric observations (total visual brightness) taken from the ICQ Archive of Photometric Data on Comets. Our present result (3.01 × 10^{28} molecules s^{-1} at 0.991 au) is in excellent agreement with that obtained by Despois et al. (1979). Assuming a fractional active surface area of 10% on the sunlit hemisphere, we estimate a minimum effective nuclear radius of 4.2 km for comet Kohler.

  19. Triplet correlation functions in liquid water

    NASA Astrophysics Data System (ADS)

    Dhabal, Debdas; Singh, Murari; Wikfeldt, Kjartan Thor; Chakravarty, Charusita

    2014-11-01

    Triplet correlations have been shown to play a crucial role in the transformation of simple liquids to anomalous tetrahedral fluids [M. Singh, D. Dhabal, A. H. Nguyen, V. Molinero, and C. Chakravarty, Phys. Rev. Lett. 112, 147801 (2014)]. Here we examine triplet correlation functions for water, arguably the most important tetrahedral liquid, under ambient conditions, using configurational ensembles derived from molecular dynamics (MD) simulations and reverse Monte Carlo (RMC) datasets fitted to experimental scattering data. Four different RMC data sets with widely varying hydrogen-bond topologies fitted to neutron and x-ray scattering data are considered [K. T. Wikfeldt, M. Leetmaa, M. P. Ljungberg, A. Nilsson, and L. G. M. Pettersson, J. Phys. Chem. B 113, 6246 (2009)]. Molecular dynamics simulations are performed for two rigid-body effective pair potentials (SPC/E and TIP4P/2005) and the monatomic water (mW) model. Triplet correlation functions are compared with other structural measures for tetrahedrality, such as the O-O-O angular distribution function and the local tetrahedral order distributions. In contrast to the pair correlation functions, which are identical for all the RMC ensembles, the O-O-O triplet correlation function can discriminate between ensembles with different degrees of tetrahedral network formation with the maximally symmetric, tetrahedral SYM dataset displaying distinct signatures of tetrahedrality similar to those obtained from atomistic simulations of the SPC/E model. Triplet correlations from the RMC datasets conform closely to the Kirkwood superposition approximation, while those from MD simulations show deviations within the first two neighbour shells. The possibilities for experimental estimation of triplet correlations of water and other tetrahedral liquids are discussed.

  20. Report of the IAU Working Group on Solar Eclipses

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.

    2015-08-01

    The Working Group on Solar Eclipses coordinates scientists and information in the study of the Sun and the heliosphere at solar eclipses. Our Website at http://eclipses.info has a wide variety of information, including links to maps and other websites dealing with solar eclipses, as well as information on how to observe the partial-phases of solar eclipses safely and why it is interesting for not only scientists but also for the public to observe eclipses and to see how we work to uncover the mysteries of the sun's upper atmosphere. In the last triennium, there were total eclipses in Australia and the Pacific in 2012; in an arc across Africa from Gabon to Uganda and Kenya in 2013; and in the Arctic, including Svalbard and the Faeroes plus many airplanes aloft, in 2015. In the coming triennium, there will be total solar eclipses in Indonesia and the Pacific in 2016 and then, on 21 August 2017, a total solar eclipse that will sweep across the Continental United States from northwest to southeast. Mapping websites, all linked to http://eclipses.info, include Fred Espenak's http://EclipseWise.com; Michael Zeiler's http://GreatAmericanEclipse.com and http://eclipse-maps.com; Xavier Jubier's http://xjubier.free.fr; and (with weather and cloudiness analysis) Jay Anderson's http://eclipser.ca. Members of the Working Group, chaired by Jay Pasachoff (U.S.), include Iraida Kim (Russia), Kiroki Kurokawa (Japan), Jagdev Singh (India), Vojtech Rusin (Slovakia), Zhongquan Qu (China), Fred Espenak (U.S.), Jay Anderson (Canada), Glenn Schneider (U.S.), Michael Gill (U.K.), Xavier Jubier (France), Michael Zeiler (U.S.), and Bill Kramer (U.S.).

  1. Spin-orbit transitions in α - and γ -CoV2O6

    NASA Astrophysics Data System (ADS)

    Wallington, F.; Arevalo-Lopez, A. M.; Taylor, J. W.; Stewart, J. R.; Garcia-Sakai, V.; Attfield, J. P.; Stock, C.

    2015-09-01

    γ -triclinic and α -monoclinic polymorphs of CoV2O6 are two of the few known transition-metal ion-based materials that display stepped 1/3 magnetization plateaus at low temperatures. Neutron diffraction [M. Markkula et al., Phys. Rev. B 86, 134401 (2012)], 10.1103/PhysRevB.86.134401, x-ray dichroism [N. Hollmann et al., Phys. Rev. B 89, 201101(R) (2014)], 10.1103/PhysRevB.89.201101, and dielectric measurements [J. Singh et al., J. Mater. Chem. 22, 6436 (2012)], 10.1039/c2jm16290c have shown a coupling between orbital, magnetic, and structural orders in CoV2O6 . We apply neutron inelastic scattering to investigate this coupling by measuring the spin-orbit transitions in both α and γ polymorphs. We find the spin exchange and anisotropy in monoclinic α -CoV2O6 to be weak in comparison with the spin-orbit coupling λ and estimate an upper limit of |J /λ |˜ 0.05 . However, the spin exchange is larger in the triclinic polymorph and we suggest the excitations are predominately two dimensional. The local compression of the octahedra surrounding the Co2 + ion results in a direct coupling between higher-energy orbital levels, the magnetic ground state, and elastic strain. CoV2O6 is therefore an example where the local distortion along with the spin-orbit coupling provides a means of intertwining structural and magnetic properties. We finish the paper by investigating the low-energy magnetic fluctuations within the ground-state doublet and report a magnetic excitation that is independent of the local crystalline electric field. We characterize the temperature and momentum dependence of these excitations and discuss possible connections to the magnetization plateaus.

  2. High-wavenumber Solar f-mode Strengthening Prior to Active Region Formation

    NASA Astrophysics Data System (ADS)

    Singh, Nishant K.; Raichur, Harsha; Brandenburg, Axel

    2016-12-01

    We report a systematic strengthening of the local solar surface or fundamental f-mode one to two days prior to the emergence of an active region (AR) in the same (corotating) location. Except for a possibly related increase in the kurtosis of the magnetic field, no indication can be seen in the magnetograms at that time. Our study is motivated by earlier numerical findings of Singh et al., which showed that, in the presence of a nonuniform magnetic field that is concentrated a few scale heights below the surface, the f-mode fans out in the diagnostic kω diagram at high wavenumbers. Here we explore this possibility using data from the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory and show for six isolated ARs, 11130, 11158, 11242, 11105, 11072, and 11768, that at large latitudinal wavenumbers (corresponding to horizontal scales of around 3000 {km}), the f-mode displays strengthening about two days prior to AR formation and thus provides a new precursor for AR formation. Furthermore, we study two ARs, 12051 and 11678, apart from a magnetically quiet patch lying next to AR 12529, to demonstrate the challenges in extracting such a precursor signal when a newly forming AR emerges in a patch that lies in close proximity to one or several already existing ARs, which are expected to pollute neighboring patches. We then discuss plausible procedures for extracting precursor signals from regions with crowded environments. The idea that the f-mode is perturbed days before any visible magnetic activity occurs at the surface can be important in constraining dynamo models aimed at understanding the global magnetic activity of the Sun.

  3. Nonadiabatic collisions of CaH with Li: Importance of spin-orbit-induced spin relaxation in spin-polarized sympathetic cooling of CaH

    NASA Astrophysics Data System (ADS)

    Warehime, Mick; Kłos, Jacek

    2015-09-01

    We apply our recently developed, quantum, nonadiabatic, two-dimensional finite element method [Warehime et al., J. Chem. Phys. 142, 034108 (2015)., 10.1063/1.4904432] to estimate the probability of the nonadiabatic reaction in spin-polarized Li (2S ) +CaH (2Σ+) . This spin-orbit-induced reaction leads to trap loss due to the opening of a barrierless pathway to the Ca (1S ) +LiH (1Σ+) products. To investigate this reaction we calculate three two-dimensional radial cuts of the potential energy surfaces for the triplet and singlet electronic states. We also calculate the spin-orbit coupling matrix element between these two electronic states. From our nonadiabatic scattering calculations we estimate the spin-flip probability in the sympathetic cooling of the CaH molecule with ultracold Li atoms to be small: on the order of 10-7 and increasing to 10-4 at higher temperatures. We estimate the order of the rate constant in our reduced dimensionality approach for the reaction proceeding on the singlet potential at a temperature of 1 K to be 10-10cm3 /s. This is of the same order as the measured value of 3.6 ×10-10cm3/s [Singh et al., Phys. Rev. Lett. 108, 203201 (2012), 10.1103/PhysRevLett.108.203201]. This reaction rate is at least seven orders of magnitude larger than our estimated rate of the spin-orbit-induced triplet to singlet reaction. Our nonadiabatic result is encouraging for the experimental prospects for this title system.

  4. The effects of drying on physical properties of bilimbi slices (Averrhoa bilimbi l.)

    NASA Astrophysics Data System (ADS)

    Shahari, N.; Nursabrina, M.; Suhairah, A. Zai

    2015-05-01

    Physical appearance analyses of fruits are used to maintain food quality throughout and at the end of processing. However, control variables have to be designed to obtained the desired food quality. In the present study, the effects of pretreatment and drying air temperatures of 50°C, 60°C and 70°C on the drying kinetics of belimbi slices were investigated using a hot-air dryer. In order to investigate and select the appropriate drying model, seven experiment based mathematical drying models were fitted to the experimental data. According to the statistical criteria (R2, SSE and RMSE), a Logarithmic model was found to be the best model to describe the drying behaviour of belimbi slices at 40°C for control; The Page/modified Page model was the best model to describe drying behaviour at 40°C, 60°C pre-treatment and 50°C for the control and the Wang and Singh model fitted well for 50°C pre-treatment and 60°C for the control. Comparison between experiment based mathematical modelling with a single phase mathematical model shows that close agreement was produced. The qualities of belimbi slices in terms of colour, texture and shrinkage with different air temperature and pre-treatment were also investigated. Higher drying temperatures gives less drying time, a lighter colour but greater product shrinkage, whilst pre-treatment can reduce product shrinkage and drying time and can also give good texture properties. The results show that pre-treatment and the drying temperature are important to improve mass and heat transfer as well as the product characteristics such as colour, shrinkage and texture.

  5. Origin of Meyer-Neldel type compensation behavior in organic semiconductors at large carrier concentrations: Disorder versus thermodynamic description

    NASA Astrophysics Data System (ADS)

    Fishchuk, I. I.; Kadashchuk, A.; Mityashin, A.; Gavrilyuk, M. M.; Köhler, A.; Bässler, H.; Genoe, J.; Sitter, H.; Sariciftci, N. S.

    2014-12-01

    We have extended an effective medium approximation theory [Fishchuk, Kadashchuk, Genoe, Ullah, Sitter, Singh, Sariciftci, and Bässler, Phys. Rev. B 81, 045202 (2010), 10.1103/PhysRevB.81.045202] to investigate how polaron formation affects the Meyer-Neldel (MN) compensation behavior observed for temperature-dependent charge-carrier transport in disordered organic semiconductors at large carrier concentrations, as realized in organic field-effect transistors (OFETs). We show that the compensation behavior in organic semiconductor thin films can be consistently described for both nonpolaronic and polaronic hopping transport in the framework of the disorder formalism using either Miller-Abrahams or polaron Marcus rates, respectively, provided that the polaron binding energy is small compared to the width of the density of states (DOS) distribution in the system. We argue that alternative models based on thermodynamic reasoning, like the multiexcitation entropy (MEE) model, which assumes charge transport dominated by polarons with multiphonon processes and ignores the energy disorder, are inherently not applicable to describe adequately the charge-carrier transport in disordered organic semiconductors. We have suggested and realized a test experiment based on measurements of the compensation behavior for the temperature-dependent conductivity and mobility in OFET devices to check the applicability of these models. We point out that the MN behavior observed in thin-film OFETs has nothing to do with the genuine MN rule predicted by the MEE approach, but rather it is an apparent effect arising as a consequence of the functional dependence of the partial filling of the DOS in a disordered system with hopping transport. This fact is fully supported by experimental results. The apparent MN energy was found to depend also on the shape of the DOS distribution and polaron binding energy.

  6. Identification of Acetylene on Titan's Surface

    NASA Astrophysics Data System (ADS)

    Singh, S.; McCord, T. B.; Rodriguez, S.; Combe, J. P.; Cornet, T.; Le Mouelic, S.; Maltagliati, L.; Chevrier, V.; Clark, R. N.

    2015-12-01

    Titan's atmosphere is opaque in the near infrared due to gaseous absorptions, mainly by methane, and scattering by aerosols, except in a few "transparency windows" (e.g., Sotin et al., 2005). Thus, the composition of Titan surface remains difficult to access from space and is still poorly constrained, limited to ethane in the polar lakes (Brown et al., 2008) and a few possible organic molecules on the surface (Clark et al., 2010). Photochemical models suggest that most of the organic compounds formed in the atmosphere are heavy enough to condense and build up at the surface in liquid and solid states over geological timescale (Cordier et al., 2009, 2011). Acetylene (C2H2) is one of the most abundant organic molecules in the atmosphere and thus thought to present on the surface as well. Here we report direct evidence of solid C2H2 on Titan's surface using Cassini Visual and Infrared Mapping Spectrometer (VIMS) data. By comparing VIMS observations and laboratory measurements of solid and liquid C2H2, we identify a specific absorption at 1.55 µm that is widespread over Titan but is particularly strong in the brightest terrains. This surface variability suggests that C2H2 is mobilized by surface processes, such as surface weathering, topography, and dissolution/evaporation. The detection of C2H2 on the surface of Titan opens new paths to understand and constrain Titan's surface activity. Since C2H2 is highly soluble in Titan liquids (Singh et al. 2015), it can easily dissolve in methane/ethane and may play an important role in carving of fluvial channels and existence of karstic lakes at higher latitudes on Titan. These processes imply the existence of a dynamic surface with a continued history of erosion and deposition of C2H2 on Titan.

  7. Determination of differential stress in the D-DIA using cubic BN anvils and 2-D monochromatic diffraction

    NASA Astrophysics Data System (ADS)

    Uchida, T.; Wang, Y.; Rivers, M. L.; Durham, W. B.; Mei, S.

    2003-04-01

    We have adopted X-ray transparent cubic boron nitride (cBN) anvils in a modified deformation DIA (D-DIA) to conduct monochromatic diffraction using a 2-D CCD detector (SMART1500). This setup allows us to obtain real-time diffraction data with complete Debye rings that are essential for accurate determination of lattice strains in the deformed sample. Experiments have been conducted on MgO to 6.3 GPa and 1273 K in the D-DIA. Samples were deformed continuously up to 30 percent axial shortening, with various strain rates between 0.001 and 0.00001 per second, under fixed confining pressure. Pressure, temperature, sample length, and monochromatic diffraction patterns were recorded repeatedly during the constant-strain rate deformation process. A monochromatic beam with a wavelength of 0.248 Angstrom (50 keV) was used for diffraction. We have developed a software package to analyze the 2-D diffraction data. After spatial and flat-field corrections, each 2-D diffraction pattern is converted into a multiple of 1-D patterns, according to a given azimuth angle range (typically binned at 1 degree intervals). The 1-D patterns are then fitted to yield information on the azimuth dependence for each lattice spacing. Lattice strain is then computed based on the well-known theory (A.K. Singh, J. Appl. Phys., 73, 4278, 1993) to convert to differential stress. This approach allows us to examine lattice strain as a function of pressure, temperature, and total plastic strain systematically. With the known pressure and temperature dependence of the elastic constants for MgO, differential stress can be evaluated throughout deformation. Details of the methodology and analysis will be presented and sources of experimental uncertainties will be discussed.

  8. Transport coefficients for the shear dynamo problem at small Reynolds numbers

    NASA Astrophysics Data System (ADS)

    Singh, Nishant K.; Sridhar, S.

    2011-05-01

    We build on the formulation developed in S. Sridhar and N. K. Singh [J. Fluid Mech.JFLSA70022-112010.1017/S0022112010003745 664, 265 (2010)] and present a theory of the shear dynamo problem for small magnetic and fluid Reynolds numbers, but for arbitrary values of the shear parameter. Specializing to the case of a mean magnetic field that is slowly varying in time, explicit expressions for the transport coefficients αil and ηiml are derived. We prove that when the velocity field is nonhelical, the transport coefficient αil vanishes. We then consider forced, stochastic dynamics for the incompressible velocity field at low Reynolds number. An exact, explicit solution for the velocity field is derived, and the velocity spectrum tensor is calculated in terms of the Galilean-invariant forcing statistics. We consider forcing statistics that are nonhelical, isotropic, and delta correlated in time, and specialize to the case when the mean field is a function only of the spatial coordinate X3 and time τ; this reduction is necessary for comparison with the numerical experiments of A. Brandenburg, K. H. Rädler, M. Rheinhardt, and P. J. Käpylä [Astrophys. J.AJLEEY0004-637X10.1086/527373 676, 740 (2008)]. Explicit expressions are derived for all four components of the magnetic diffusivity tensor ηij(τ). These are used to prove that the shear-current effect cannot be responsible for dynamo action at small Re and Rm, but for all values of the shear parameter.

  9. Morphotropic phase boundary of heterovalent perovskite solid solutions: Experimental and theoretical investigation of Pb Sc1/2 Nb1/2 O3 -PbTi O3

    NASA Astrophysics Data System (ADS)

    Haumont, R.; Al-Barakaty, A.; Dkhil, B.; Kiat, J. M.; Bellaiche, L.

    2005-03-01

    X-ray and neutron diffraction techniques are combined with first-principles-based simulations to derive and understand the structural properties of Pb(Sc,Nb,Ti)O3 (PSN-PT) near its morphotropic phase boundary (MPB). An analysis of our measurements yields, at room and low temperatures, an overall tetragonal T —monoclinic MC —monoclinic MB —rhombohedral R path (when adopting the notations of Vanderbilt and Cohen, Phys. Rev. B 63, 94108 (2001) for the monoclinic phases) as the Ti composition decreases across the MPB. A composition- and temperature-dependent significant mixing between some of these phases is also measured and reported here. The overall T-MC-MB-R path, which has also been proposed for Pb(Mg,Nb,Ti)O3 [A. K. Singh and D. Pandey, Phys. Rev. B 67, 64102 (2003)] is rather complex since it involves a change in the polarization path: this polarization first rotates in a (100) plane for the T-MC part of the path and then in a (1-10) plane for the MB-R part of the path. Moreover, a comparison between these measurements and first-principles-based calculations raises the possibility that this complex path, and the associated MC and MB phases, can only occur if the samples exhibit a deviation from a perfectly homogeneous and disordered situation, e.g. possess nanoscale chemically-ordered regions. If not, homogeneously disordered PSN-PT is predicted to exhibit at low temperature the same polarization path as Pb(Zr,Ti)O3 , that is T -monoclinic MA-R which involves a “single” polarization rotation in a (1-10) plane. Nanoscale inhomogeneity may thus play a key role on the macroscopic properties of PSN-PT, in particular, and of other heterovalent complex solid solutions, in general, near their MPB.

  10. Evaluation of simulated photochemical partitioning of oxidized nitrogen in the upper troposphere

    NASA Astrophysics Data System (ADS)

    Henderson, B. H.; Pinder, R. W.; Crooks, J.; Cohen, R. C.; Hutzell, W. T.; Sarwar, G.; Goliff, W. S.; Stockwell, W. R.; Fahr, A.; Mathur, R.; Carlton, A. G.; Vizuete, W.

    2010-08-01

    Regional and global chemical transport models underpredict NOx (NO+NO2) in the upper troposphere where it is a precursor to the greenhouse gas ozone. The NOx bias been shown in model evaluations using aircraft data (Singh et al., 2007) and total column NO2 (molecules cm-2) from satellite observations (Napelenok et al., 2008). The causes of NOx underpredictions have yet to be fully understood due to the interconnected nature of simulated emission, transport, and chemistry processes. Recent observation-based studies suggest that, in the upper troposphere, simulated chemistry overpredicts hydrogen radicals (OH• and HO2•) and would convert NOx to HNO3 too quickly (Olson et al., 2006; Bertram et al., 2007; Ren et al., 2008). Since typical chemistry evaluation techniques are not available for upper tropospheric conditions, this study develops an evaluation platform from in situ observations, stochastic convection, and deterministic chemistry. We derive a stochastic convection model and optimize it using two simulated datasets of time since convection, one based on meteorology and the other on chemistry. The chemistry surrogate for time since convection is calculated using seven different chemical mechanisms, all of which predict shorter time since convection than our meteorological analysis. We evaluate chemical simulations by inter-comparison and by pairing results with observations based on NOx:HNO3, a photochemical aging indicator. Inter-comparison reveals individual chemical mechanism biases and recommended updates. Evaluation against observations shows that all chemical mechanisms overpredict NOx removal relative to long-lived methanol and carbon monoxide. All chemical mechanisms underpredict observed NOx by at least 30%, and further evaluation is necessary to refine simulation sensitivities to initial conditions and chemical rate uncertainties.

  11. NOx Chemical Sinks in the Upper Troposphere

    NASA Astrophysics Data System (ADS)

    Henderson, B. H.; Pinder, R. W.; Crooks, J.; Cohen, R. C.; Hutzell, W. T.; Sarwar, G.; Goliff, W. S.; Stockwell, W. R.; Fahr, A.; Mathur, R.; Carlton, A. G.; Vizuete, W.

    2010-12-01

    Chemical transport model evaluations in the upper troposphere (UT) have shown a NOx low-bias (Singh et al., 2007; Napelenok et al., 2008) and HOx high-bias (Bertram et al., 2007, Ren et al., 2008). The combined biases suggest an over-prediction of simulated chemical sinks of NOx. We developed a model framework that isolates gas-phase chemistry for evaluation against in situ INTEX-NA aircraft measurements. We evaluated seven chemical mechanisms (CB05, RACM2, SAPRC99, SAPRC07, GEOS-Chem, MOZART4, and MCM) whose designs range from near-explicit to condensed, and whose intended scales range from point to global simulation. Our evaluation finds that chemical sinks of NOx cause a 30% under-prediction of NOx. Inter-mechanism comparison identified inconsistencies and recommendations, but did not meaningfully improve over-estimation of simulated NOx chemical sinks. We designed experiments to test the model sensitivity to initial conditions, heterogeneous processing, and gas-phase reaction rate uncertainty. Initial results suggest that the over-prediction of chemical sinks is robust to uncertainty in initial conditions, but can be improved by adjusting reaction rate constants. Adding heterogeneous processing exacerbated the loss of NOx via N2O5 conversion to HNO3. We then tested sensitivity to reaction coefficients by re-evaluating the GEOS-Chem mechanism with each of its 293 reactions adjusted by 10%. We find that the chemical lifetime of NOx is most sensitive to OH + NO2 and HO2 + NO, which both have high JPL reported uncertainty at low temperatures. The rapid chemical loss of NOx suggests over estimation of total oxidation, which influences ozone in the upper troposphere where it most efficiently absorbs outgoing radiation. The oxidation bias will also influence the results of NOx sink attribution and O3 source attributions. To reduce the uncertainty in chemical sinks of NOx, we need further kinetic studies of HOx + NOx reactions under UT relevant conditions.

  12. OCS Trimer and Tetramer: Calculated Structures and Infrared Spectra

    NASA Astrophysics Data System (ADS)

    Dehghany, Mehdi; Moazzen-Ahmadi, Nasser; McKellar, Bob

    2014-06-01

    An OCS trimer was originally observed in the 1990s by microwave spectroscopy. New broadband chirped-pulse microwave spectra (preceding talk) reveal an OCS tetramer and a second distinct trimer isomer. In the present talk, we discuss OCS cluster structures and infrared spectra. Our structure calculations are based on a recent ab initio potential energy surface and assume pairwise additivity. There are also recent direct ab initio trimer and tetramer calculations, which are (necessarily) at a lower level of theory. We find that the observed OCS trimers indeed correspond to the two lowest energy isomers in both calculations, and that there is fairly good agreement of experimental and theoretical structures. For the tetramer the global minimum is at -2773 wn relative to dissociation, and we calculate (at least) twenty different isomers within 100 wn of this minimum (and seven within 20 wn). Remarkably, the observed microwave tetramer does correspond to our lowest calculated isomer. However this isomer is not included in the published direct ab initio calculation - it may just have been overlooked due to the large number of isomers! In the mid-infrared region of the OCS νb{1} fundamental (˜2060 wn), we observe two bands which are clearly due to the same microwave OCS tetramer. But a third band is assigned to a different tetramer not observed in the microwave spectrum. It appears to correspond to our seventh calculated isomer, located about 20 wn above the most stable one, and it is also missing from the direct ab initio calculation. Neither observed tetramer has any symmetry elements. J.P. Connelly, A. Bauder, A. Chisholm, and B.J. Howard, Mol. Phys. 88, 915 (1996) R.A. Peebles and R.L. Kuczkowski, J. Phys. Chem. A 103, 6344 (1999). N. Sahu, G. Singh, and S.R. Gadre, J. Phys. Chem. A 117, 10964 (2013).

  13. Measurement of DNA damage after exposure to 2450 MHz electromagnetic radiation.

    PubMed

    Malyapa, R S; Ahern, E W; Straube, W L; Moros, E G; Pickard, W F; Roti Roti, J L

    1997-12-01

    Recent reports suggest that exposure to 2450 MHz electromagnetic radiation causes DNA single-strand breaks (SSBs) and double-strand breaks (DSBs) in cells of rat brain irradiated in vivo (Lai and Singh, Bioelectromagnetics 16, 207-210, 1995; Int. J. Radiat. Biol. 69, 513-521, 1996). Therefore, we endeavored to determine if exposure of cultured mammalian cells in vitro to 2450 MHz radiation causes DNA damage. The alkaline comet assay (single-cell gel electrophoresis), which is reportedly the most sensitive method to assay DNA damage in individual cells, was used to measure DNA damage after in vitro 2450 MHz irradiation. Exponentially growing U87MG and C3H 10T1/2 cells were exposed to 2450 MHz continuous-wave (CW) radiation in specially designed radial transmission lines (RTLs) that provided relatively uniform microwave exposure. Specific absorption rates (SARs) were calculated to be 0.7 and 1.9 W/kg. Temperatures in the RTLs were measured in real time and were maintained at 37 +/- 0.3 degrees C. Every experiment included sham exposure(s) in an RTL. Cells were irradiated for 2 h, 2 h followed by a 4-h incubation at 37 degrees C in an incubator, 4 h and 24 h. After these treatments samples were subjected to the alkaline comet assay as described by Olive et al. (Exp. Cell Res. 198, 259-267, 1992). Images of comets were digitized and analyzed using a PC-based image analysis system, and the "normalized comet moment" and "comet length" were determined. No significant differences were observed between the test group and the controls after exposure to 2450 MHz CW irradiation. Thus 2450 MHz irradiation does not appear to cause DNA damage in cultured mammalian cells under these exposure conditions as measured by this assay.

  14. DNA damage in rat brain cells after in vivo exposure to 2450 MHz electromagnetic radiation and various methods of euthanasia.

    PubMed

    Malyapa, R S; Ahern, E W; Bi, C; Straube, W L; LaRegina, M; Pickard, W F; Roti Roti, J L

    1998-06-01

    The present study was done to confirm the reported observation that low-intensity acute exposure to 2450 MHz radiation causes DNA single-strand breaks (Lai and Singh, Bioelectromagnetics 16, 207-210, 1995). Male Sprague-Dawley rats weighing approximately 250 g were irradiated with 2450 MHz continuous-wave (CW) microwaves for 2 h at a specific absorption rate of 1.2 W/kg in a cylindrical waveguide system (Guy et al., Radio Sci. 14, 63-74, 1979). There was no associated rise in the core body temperature of the rats. After the irradiation or sham treatments, rats were euthanized by either CO2 asphyxia or decapitation by guillotine (eight pairs of animals per euthanasia group). After euthanasia the brains were removed and immediately immersed in cold Ames medium and the cells of the cerebral cortex and the hippocampus were dissociated separately and subjected to the alkaline comet assay. Irrespective of whether the rats were euthanized by CO2 asphyxia or decapitated by guillotine, no significant differences were observed between either the comet length or the normalized comet moment of cells from either the cerebral cortex or the hippocampus of sham-treated rats and those from the irradiated rats. However, the data for the rats asphyxiated with CO2 showed more intrinsic DNA damage and more experiment-to-experiment variation than did the data for rats euthanized by guillotine. Therefore, the guillotine method of euthanasia is the most appropriate in studies relating to DNA damage. Furthermore, we did not confirm the observation that DNA damage is produced in cells of the rat cerebral cortex or the hippocampus after a 2-h exposure to 2450 MHz CW microwaves or at 4 h after the exposure.

  15. Phenazine-1-Carboxylic Acid Promotes Bacterial Biofilm Development via Ferrous Iron Acquisition▿†

    PubMed Central

    Wang, Yun; Wilks, Jessica C.; Danhorn, Thomas; Ramos, Itzel; Croal, Laura; Newman, Dianne K.

    2011-01-01

    The opportunistic pathogen Pseudomonas aeruginosa forms biofilms, which render it more resistant to antimicrobial agents. Levels of iron in excess of what is required for planktonic growth have been shown to promote biofilm formation, and therapies that interfere with ferric iron [Fe(III)] uptake combined with antibiotics may help treat P. aeruginosa infections. However, use of these therapies presumes that iron is in the Fe(III) state in the context of infection. Here we report the ability of phenazine-1-carboxylic acid (PCA), a common phenazine made by all phenazine-producing pseudomonads, to help P. aeruginosa alleviate Fe(III) limitation by reducing Fe(III) to ferrous iron [Fe(II)]. In the presence of PCA, a P. aeruginosa mutant lacking the ability to produce the siderophores pyoverdine and pyochelin can still develop into a biofilm. As has been previously reported (P. K. Singh, M. R. Parsek, E. P. Greenberg, and M. J. Welsh, Nature 417:552-555, 2002), biofilm formation by the wild type is blocked by subinhibitory concentrations of the Fe(III)-binding innate-immunity protein conalbumin, but here we show that this blockage can be rescued by PCA. FeoB, an Fe(II) uptake protein, is required for PCA to enable this rescue. Unlike PCA, the phenazine pyocyanin (PYO) can facilitate biofilm formation via an iron-independent pathway. While siderophore-mediated Fe(III) uptake is undoubtedly important at early stages of infection, these results suggest that at later stages of infection, PCA present in infected tissues may shift the redox equilibrium between Fe(III) and Fe(II), thereby making iron more bioavailable. PMID:21602354

  16. Induction of CaSR expression circumvents the molecular features of malignant CaSR null colon cancer cells.

    PubMed

    Singh, Navneet; Chakrabarty, Subhas

    2013-11-15

    We recently reported on the isolation and characterization of calcium sensing receptor (CaSR) null human colon cancer cells (Singh et al., Int J Cancer 2013; 132: 1996-2005). CaSR null cells possess a myriad of molecular features that are linked to a highly malignant and drug resistant phenotype of colon cancer. The CaSR null phenotype can be maintained in defined human embryonic stem cell culture medium. We now show that the CaSR null cells can be induced to differentiate in conventional culture medium, regained the expression of CaSR with a concurrent reversal of the cellular and molecular features associated with the null phenotype. These features include cellular morphology, expression of colon cancer stem cell markers, expression of survivin and thymidylate synthase and sensitivity to fluorouracil. Other features include the expression of epithelial mesenchymal transition linked molecules and transcription factors, oncogenic miRNAs and tumor suppressive molecule and miRNA. With the exception of cancer stem cell markers, the reversal of molecular features, upon the induction of CaSR expression, is directly linked to the expression and function of CaSR because blocking CaSR induction by shRNA circumvented such reversal. We further report that methylation and demethylation of the CaSR gene promoter underlie CaSR expression. Due to the malignant nature of the CaSR null cells, inclusion of the CaSR null phenotype in disease management may improve on the mortality of this disease. Because CaSR is a robust promoter of differentiation and mediates its action through diverse mechanisms and pathways, inactivation of CaSR may serve as a new paradigm in colon carcinogenesis.

  17. Triplet correlation functions in liquid water

    SciTech Connect

    Dhabal, Debdas; Chakravarty, Charusita; Singh, Murari; Wikfeldt, Kjartan Thor

    2014-11-07

    Triplet correlations have been shown to play a crucial role in the transformation of simple liquids to anomalous tetrahedral fluids [M. Singh, D. Dhabal, A. H. Nguyen, V. Molinero, and C. Chakravarty, Phys. Rev. Lett. 112, 147801 (2014)]. Here we examine triplet correlation functions for water, arguably the most important tetrahedral liquid, under ambient conditions, using configurational ensembles derived from molecular dynamics (MD) simulations and reverse Monte Carlo (RMC) datasets fitted to experimental scattering data. Four different RMC data sets with widely varying hydrogen-bond topologies fitted to neutron and x-ray scattering data are considered [K. T. Wikfeldt, M. Leetmaa, M. P. Ljungberg, A. Nilsson, and L. G. M. Pettersson, J. Phys. Chem. B 113, 6246 (2009)]. Molecular dynamics simulations are performed for two rigid-body effective pair potentials (SPC/E and TIP4P/2005) and the monatomic water (mW) model. Triplet correlation functions are compared with other structural measures for tetrahedrality, such as the O–O–O angular distribution function and the local tetrahedral order distributions. In contrast to the pair correlation functions, which are identical for all the RMC ensembles, the O–O–O triplet correlation function can discriminate between ensembles with different degrees of tetrahedral network formation with the maximally symmetric, tetrahedral SYM dataset displaying distinct signatures of tetrahedrality similar to those obtained from atomistic simulations of the SPC/E model. Triplet correlations from the RMC datasets conform closely to the Kirkwood superposition approximation, while those from MD simulations show deviations within the first two neighbour shells. The possibilities for experimental estimation of triplet correlations of water and other tetrahedral liquids are discussed.

  18. Human-associated fungi in deep subseafloor sediment?

    NASA Astrophysics Data System (ADS)

    Fulfer, V. M.; Kirkpatrick, J. B.; D'Hondt, S.

    2015-12-01

    Recent studies have reported fungi in marine sediment samples from depths as great as 1740 meters below seafloor (mbsf) (Rédou et al., 2014). Such studies have utilized a variety of techniques to identify fungi, including cultivation of isolates, amplicon sequencing, and metagenomics. Six recent studies of marine sediment collectively identify nearly 100 fungal taxa at the genus and species levels (Damare et al., 2006; Lai et al., 2007; Edgcomb et al., 2010; Singh et al., 2010; Orsi et al., 2013; Rédou et al., 2014). Known marine taxa are rarely identified by these studies. For individual studies with more than two taxa, between 16% and 57% of the fungal taxa are human microflora or associated with human environments (e.g., human skin or indoor air). For example, three of the six studies identified Malassezia species that are common skin inhabitants of humans and dogs. Although human-associated taxa have been identified in both shallow and deep sediment, they pose a particularly acute problem for deep subseafloor samples, where claims of a eukaryotic deep biosphere are most striking; depending on the study, 25% to 38% of species identified in sediment taken at depths greater than 40 meters are human-associated. Only one to three species have been reported from each of the four samples taken at depths greater than one km (eight species total; Rédou et al., 2014). Of these eight species, three are human-associated. This ubiquity of human-associated microflora is very problematic for interpretations of an indigenous deep subseafloor fungal community; either human-associated taxa comprise a large fraction of marine sedimentary fungi, or sample and analytical contamination is so widespread that the extent and ubiquity of a deep subseafloor fungal community remains uncertain. This highlights the need for stringent quality control measures throughout coring, sampling, and recovery of marine sediment, and when cultivating, extracting, and/or sequencing fungi from

  19. Scaffold of Asymmetric Organic Compounds - Magnetite Plaquettes

    NASA Technical Reports Server (NTRS)

    Chan, Q. H. S.; Zolensky, M. E.; Martinez, J.

    2015-01-01

    Life on Earth shows preference towards the set of organics with particular spatial configurations, this 'selectivity' is a crucial criterion for life. With only rare exceptions, life prefers the left- (L-) form over the right- (D-) form of amino acids, resulting in an L-enantiomeric excess (L-ee). Recent studies have shown Lee for alpha-methyl amino acids in some chondrites. Since these amino acids have limited terrestrial occurrence, the origin of their stereoselectivity is nonbiological, and it seems appropriate to conclude that chiral asymmetry, the molecular characteristic that is common to all terrestrial life form, has an abiotic origin. A possible abiotic mechanism that can produce chiral asymmetry in meteoritic amino acids is their formation with the presence of asymmetric catalysts, as mineral crystallization can produce spatially asymmetric structures. Magnetite is shown to be an effective catalyst for the formation of amino acids that are commonly found in chondrites. Magnetite 'plaquettes' (or 'platelets'), first described by Jedwab, show an interesting morphology of barrel-shaped stacks of magnetite disks with an apparent dislocation-induced spiral growth that seem to be connected at the center. A recent study by Singh et al. has shown that magnetites can self-assemble into helical superstructures. Such molecular asymmetry could be inherited by adsorbed organic molecules. In order to understand the distribution of 'spiral' magnetites in different meteorite classes, as well as to investigate their apparent spiral configurations and possible correlation to molecular asymmetry, we observed polished sections of carbonaceous chondrites (CC) using scanning electron microscope (SEM) imaging. The sections were also studied by electron backscattered diffraction (EBSD) in order to reconstruct the crystal orientation along the stack of magnetite disks.

  20. Mw Systematic Study of Alkaloids: the Distorted Tropane of Scopoline

    NASA Astrophysics Data System (ADS)

    Ecija, Patricia; Cocinero, Emilio J.; Basterretxea, Francisco J.; Fernandez, Jose A.; Castano, Fernando; Lesarri, Alberto

    2013-06-01

    Tropane alkaloids have diverse pharmacological uses and are well-known for their neurostimulant activity. Previous structure-activity-relationship established correlations between bioactivity and several aspects of ligand conformation and stereochemistry, including delicate intramolecular effects like nitrogen inversion^{a}. We have initiated a series of structural studies on tropane alkaloids^{b}, aimed to discerning their intrinsic stereochemical properties using rotational spectroscopy in supersonic jets^{c}. Here we extend these studies to the epoxytropanes, initially motivated to interrogate the influence of the epoxy group on nitrogen inversion and ring conformation. The rotational spectrum evidences a single structure in the gas phase, providing a first description of the (three ring) structurally-distorted tropane in scopoline. The determined rotational parameters of scopoline reveal the structural consequences of the intramolecular cyclation of scopine, which breaks the original epoxy group and creates a new ether bridge and a 7β-hydroxytropane configuration. The hydroxyl group further stabilizes the molecule by an O-H \\cdots N intramolecular hydrogen bond, which, in turn, forces the N-methyl group to the less stable axial form^{b}. The experimental work was supported by ab initio and DFT calculations. ^{a} i) S.Singh, Chem. Rev. 100, 925 (2000); ii) A. Krunic, D. Pan, W.J. Dunn III, S.V.S. Miariappan, Bioorg. & Med. Chem. 17, 811 (2009). ^{b} E.J. Cocinero, A. Lesarri, P. écija, J.-U. Grabow, J.A. Fernández, F. Castaño, Phys. Chem. Chem. Phys. 12, 6076 (2010). ^{c} E.J. Cocinero, A. Lesarri, P. écija, J.-U. Grabow, J.A. Fernández, F. Castaño, Phys. Chem. Chem. Phys. 12, 12486 (2010).

  1. Semiclassical approach to model quantum fluids using the statistical associating fluid theory for systems with potentials of variable range.

    PubMed

    Trejos, Víctor M; Gil-Villegas, Alejandro

    2012-05-14

    Thermodynamic properties of quantum fluids are described using an extended version of the statistical associating fluid theory for potentials of variable range (SAFT-VR) that takes into account quantum corrections to the Helmholtz free energy A, based on the Wentzel-Kramers-Brillouin approximation. We present the theoretical background of this approach (SAFT-VRQ), considering two different cases depending on the continuous or discontinuous nature of the particles pair interaction. For the case of continuous potentials, we demonstrate that the standard Wigner-Kirkwood theory for quantum fluids can be derived from the de Broglie-Bohm formalism for quantum mechanics that can be incorporated within the Barker and Henderson perturbation theory for liquids in a straightforward way. When the particles interact via a discontinuous pair potential, the SAFT-VR method can be combined with the perturbation theory developed by Singh and Sinha [J. Chem. Phys. 67, 3645 (1977); and ibid. 68, 562 (1978)]. We present an analytical expression for the first-order quantum perturbation term for a square-well potential, and the theory is applied to model thermodynamic properties of hydrogen, deuterium, neon, and helium-4. Vapor-liquid equilibrium, liquid and vapor densities, isochoric and isobaric heat capacities, Joule-Thomson coefficients and inversion curves are predicted accurately with respect to experimental data. We find that quantum corrections are important for the global behavior of properties of these fluids and not only for the low-temperature regime. Predictions obtained for hydrogen compare very favorably with respect to cubic equations of state.

  2. Half-metallic superconducting triplet spin valve

    NASA Astrophysics Data System (ADS)

    Halterman, Klaus; Alidoust, Mohammad

    2016-08-01

    We theoretically study a finite-size S F1N F2 spin valve, where a normal metal (N ) insert separates a thin standard ferromagnet (F1) and a thick half-metallic ferromagnet (F2). For sufficiently thin superconductor (S ) widths close to the coherence length ξ0, we find that changes to the relative magnetization orientations in the ferromagnets can result in substantial variations in the transition temperature Tc, consistent with experimental results [Singh et al., Phys. Rev. X 5, 021019 (2015), 10.1103/PhysRevX.5.021019]. Our results demonstrate that, in good agreement with the experiment, the variations are largest in the case where F2 is in a half-metallic phase and thus supports only one spin direction. To pinpoint the origins of this strong spin-valve effect, both the equal-spin f1 and opposite-spin f0 triplet correlations are calculated using a self-consistent microscopic technique. We find that when the magnetization in F1 is tilted slightly out of plane, the f1 component can be the dominant triplet component in the superconductor. The coupling between the two ferromagnets is discussed in terms of the underlying spin currents present in the system. We go further and show that the zero-energy peaks of the local density of states probed on the S side of the valve can be another signature of the presence of superconducting triplet correlations. Our findings reveal that for sufficiently thin S layers, the zero-energy peak at the S side can be larger than its counterpart in the F2 side.

  3. Iodine nutritional status in Uttarakhand State, India

    PubMed Central

    Sareen, Neha; Kapil, Umesh; Nambiar, Vanisha; Pandey, Ravindra Mohan; Khenduja, Preetika

    2016-01-01

    Introduction: Uttarakhand (UK) state is a known endemic region to iodine deficiency (ID). Objective: To assess the current status of iodine nutrition in a population of UK. Methodology: Three districts, namely Udham Singh Nagar (USN), Nainital (N), and Pauri Garhwal (PG) were selected. In each district, 30 clusters were identified by utilizing the population proportional to size cluster sampling methodology. Total of 6143 school age children (SAC) (USN; 1807, N; 2269, PG: 2067), 5430 adolescent girls (AGs) (USN; 1823, N; 1811, PG: 1796), 1727 pregnant mothers (PMs) (USN; 632, N; 614, PG: 481), and 2013 Neonates (USN; 649, N; 670, PG: 694), were included in the study. Clinical examination of thyroid of each child, AG and PM was conducted. Spot urine and salt samples were collected from children, AGs and PMs. Cord blood samples were collected from neonates for estimation of thyroid stimulating hormone (TSH). Results: In SAC, total goiter rate (TGR) was 13.2% (USN), 15.9% (N), and 16.8% (PG). Median urinary iodine concentration (UIC) level was 150 μg/l (USN), 125 μg/l (N), and 115 μg/l (PG). In AGs, TGR was 6.8% (USN), 8.2% (N) and 5.6% (PG). Median UIC level was 250 μg/l (USN), 200 μg/l (N), and 183 μg/l (PG). In PMs, TGR was 16.1% (USN), 20.2% (N), and 24.9% (PG). Median UIC level was 124 μg/l (USN), 117.5 μg/l (N) and 110 μg/l (PG), respectively. In Neonates, TSH levels of >5 mIU/L were found in 55.3 (USN), 76.4 (N) and 72.8 (PG) percent of neonates. Conclusion: UIC level in PMs and TSH levels among neonates indicate the prevalence of ID in three districts surveyed. PMID:27042411

  4. Novel adaptive responses revealed by transcription profiling of a Synechocystis sp. PCC 6803 delta-isiA mutant in the presence and absence of hydrogen peroxide.

    PubMed

    Singh, Abhay K; Li, Hong; Bono, Lisa; Sherman, Louis A

    2005-06-01

    The isiAB genes have proven to be highly stress-responsive under a variety of environmental conditions, including iron deficiency, high salt and oxidative stress. In order to understand the function of IsiA and its importance in oxidative stress, we constructed a knock out mutant of the isiA gene and compared differential gene expression of the DeltaisiA strain in the presence and absence of H2O2. We used the full genome microarray for the cyanobacterium Synechocystis sp. PCC 6803 as previously described [Postier BL, Wang HL, Singh A, Impson L, Andrews, HL, Klahn J, Li H, Risinger G, Pesta D, Deyholos M, Galbraith DW, Sherman LA and Burnap RL (2003) BMC Genenomics 4: 23-34]. We determined that one of the main differences in DeltaisiA compared to wild-type (in the absence of peroxide) was the induction of a gene cluster (sll1693-sll1696) that encoded genes resembling pilins or general secretory proteins (Gsp). These proteins are targeted to the cytoplasmic membrane and we suggest that they may be involved in the assembly of membrane complexes, including pigment-protein complexes. The DeltaisiA strain was more resistant to H2O2 compared to the wild-type. In the presence of 1.5 mM H2O2 for 30 min, a cluster of genes that includes a peroxiredoxin was induced 7- to 8-fold and we suggest that this peroxide scavenging enzyme is responsible for the increased peroxide resistance of the DeltaisiA strain.

  5. A DNA element in the slo gene modulates ethanol tolerance.

    PubMed

    Krishnan, Harish R; Li, Xiaolei; Ghezzi, Alfredo; Atkinson, Nigel S

    2016-03-01

    In Drosophila, the slo gene encodes BK-type Ca(2+)-activated K(+) channels and is involved in producing rapid functional tolerance to sedation with ethanol. Drosophila are ideal for the study of functional ethanol tolerance because the adult does not acquire metabolic ethanol tolerance (Scholz, Ramond, Singh, & Heberlein, 2000). It has been shown that mutations in slo block the capacity to acquire tolerance, that sedation with ethanol vapor induces slo gene expression in the nervous system, and that transgenic induction of slo can phenocopy tolerance (Cowmeadow, Krishnan, & Atkinson, 2005; Cowmeadow et al., 2006). Here we use ethanol-induced histone acetylation to map a DNA regulatory element in the slo transcriptional control region and functionally test the element for a role in producing ethanol tolerance. Histone acetylation is commonly associated with activating transcription factors. We used the chromatin immunoprecipitation assay to map histone acetylation changes following ethanol sedation to identify an ethanol-responsive DNA element. Ethanol sedation induced an increase in histone acetylation over a 60 n DNA element called 6b, which is situated between the two ethanol-responsive neural promoters of the slo gene. Removal of the 6b element from the endogenous slo gene affected the production of functional ethanol tolerance as assayed in an ethanol-vapor recovery from sedation assay. Removal of element 6b extended the period of functional ethanol tolerance from ∼10 days to more than 21 days after a single ethanol-vapor sedation. This study demonstrates that mapping the position of ethanol-induced histone acetylation is an effective way to identify DNA regulatory elements that help to mediate the response of a gene to ethanol. Using this approach, we identified a DNA element, which is conserved among Drosophila species, and which is important for producing a behaviorally relevant ethanol response.

  6. Differential gene expression and subcellular targeting of Arabidopsis glutathione S-transferase F8 is achieved through alternative transcription start sites.

    PubMed

    Thatcher, Louise F; Carrie, Chris; Andersson, Carol R; Sivasithamparam, Krishnapillai; Whelan, James; Singh, Karam B

    2007-09-28

    Glutathione S-transferases (GSTs) play major roles in the protection of plants from biotic and abiotic stresses through the detoxification of xenobiotics and toxic endogenous products. This report describes additional complexity in the regulation of the well characterized stress-responsive Arabidopsis thaliana GSTF8 promoter. This complexity results from the use of multiple transcription start sites (TSS) to give rise to alternate GSTF8 transcripts with the potential to produce two in-frame proteins differing only in their N-terminal sequence. In addition to the originally mapped TSS (Chen, W., Chao, G., and Singh, K. B. (1996) Plant J. 10, 955-966), a further nine TSS have been identified, with the majority clustered into a distinct group. The most 3' TSS gives rise to the major message (GSTF8-S) and the shorter form of the protein, whereas those originating from upstream TSS (GSTF8-L) are more weakly expressed and encode for the larger form of the protein. Differential tissue-specific and stress-responsive expression patterns were observed (e.g. GSTF8-L is more highly expressed in leaves compared with roots, whereas GSTF8-S expression has the opposite pattern and is much more stress-responsive). Analysis of GSTF8-L and GSTF8-S proteins demonstrated that GSTF8-L is solely targeted to plastids, whereas GSTF8-S is cytoplasmic. In silico analysis revealed potential conservation of GSTF8-S across a wide range of plants; in contrast, conservation of GSTF8-L was confined to the Brassicaceae. These studies demonstrate that alternate TSS of the GSTF8 promoter are used to confer differential tissue-specific and stress-responsive expression patterns as well as to target the same protein to two different subcellular localizations.

  7. Recovering the slip history of a scenario earthquake in the Mexican subduction zone

    NASA Astrophysics Data System (ADS)

    Hjorleifsdottir, V.; Perez-Campos, X.; Iglesias, A.; Cruz-Atienza, V.; Ji, C.; Legrand, D.; Husker, A. L.; Kostoglodov, V.; Valdes Gonzalez, C.

    2011-12-01

    The Guerrero segment of the Mexican subduction zone has not experienced a large earthquake for almost 100 years (Singh et al., 1981). Due to its proximity to Mexico City, which was devastated by an earthquake in the more distant Michoacan segment in 1985, it has been studied extensively in recent years. Silent slip events have been observed by a local GPS network (Kostoglodov et al. 2003) and seismic observations from a dense linear array of broadband seismometers (MASE) have provided detailed images of the crustal structure of this part of the subduction zone (see for example Pérez-Campos et al., 2008, Iglesias et al., 2010). Interestingly the part of the fault zone that is locked during the inter-seismic period is thought to reach up to or inland from the coast line. In the event of a large megathrust earthquake, this geometry could allow recordings from above the fault interface. These types of recordings can be critical to resolve the history of slip as a function of time on the fault plane during the earthquake. A well constrained model of slip-time history, together with other observations as mentioned above, could provide very valuable insights into earthquake physics and the earthquake cycle. In order to prepare the scientific response for such an event we generate a scenario earthquake in the Guerrero segment of the subduction zone. We calculate synthetic strong motion records, seismograms for global stations and static offsets on the Earth's surface. To simulate the real data available we add real noise, recorded during times of no earthquake, to the synthetic data. We use a simulated annealing inversion algorithm (Ji et al., 1999) to invert the different datasets and combinations thereof for the time-history of slip on the fault plane. We present the recovery of the slip model using the different datasets, as well as idealized datasets, investigating the expected and best possible levels of recovery.

  8. Tapeworms (Cestoda: Caryophyllidea), parasites of Clarias batrachus (Pisces: Siluriformes) in the Indomalayan region.

    PubMed

    Ash, Anirban; Scholz, Tomáš; Oros, Mikuláš; Kar, Pradip Kumar

    2011-06-01

    Revision of monozoic cestodes (Caryophyllidea) parasitic in commercially important walking catfish Clarias batrachus (L.) in tropical Asia (Indomalayan zoogeographical region) was carried out, based on the evaluation of newly collected material from India, Indonesia, and Thailand, as well as a study of type specimens. Instead of the 59 nominal taxa of 15 genera from 3 caryophyllidean families previously described, only 8 species of the Lytocestidae are considered to be valid: Bovienia indica (Niyogi, Gupta and Agarwal, 1982) n. comb.; Bovienia raipurensis (Satpute and Agarwal, 1980) Mackiewicz, 1994; Bovienia serialis (Bovien, 1926) Fuhrmann, 1931; Djombangia penetrans Bovien, 1926; Lucknowia microcephala (Bovien, 1926) n. comb.; Lytocestus indicus (Moghe, 1925) Woodland 1926; Pseudocaryophyllaeus ritai Gupta and Singh, 1983; and Pseudocaryophyllaeus tenuicollis (Bovien, 1926) n. comb. All valid species are redescribed and SEM photomicrographs of their scolices and photomicrographs of their eggs are provided for the first time. Crescentovitus Murhar, 1963, Heeradevina Srivastav and Khare, 2005, Pseudobatrachus Pathak and Srivastav, 2005, Pseudobilobulata Srivastav and Lohia, 2002, Pseudoclariasis Pathak, 2002, and Pseudoinverta Pathak, 2002 are invalidated and 50 nominal species are newly synonymized, including 4 species described from other fish hosts. Taxonomic status of the remaining caryophyllidean taxa reported from C. batrachus (at least 6 taxa) could not be clarified because of the unavailability of their original descriptions. A key to identification of caryophyllidean tapeworms parasitic in C. batrachus is provided. To avoid current inflation of descriptions of invalid taxa, researchers are strongly encouraged to work only with well-fixed material; damaged, decomposed, or strongly flattened specimens should not be used for taxonomic studies, and type specimens must always be deposited in internationally recognized collections.

  9. A simple approximation of moments of the quasi-equilibrium distribution of an extended stochastic theta-logistic model with non-integer powers.

    PubMed

    Bhowmick, Amiya Ranjan; Bandyopadhyay, Subhadip; Rana, Sourav; Bhattacharya, Sabyasachi

    2016-01-01

    The stochastic versions of the logistic and extended logistic growth models are applied successfully to explain many real-life population dynamics and share a central body of literature in stochastic modeling of ecological systems. To understand the randomness in the population dynamics of the underlying processes completely, it is important to have a clear idea about the quasi-equilibrium distribution and its moments. Bartlett et al. (1960) took a pioneering attempt for estimating the moments of the quasi-equilibrium distribution of the stochastic logistic model. Matis and Kiffe (1996) obtain a set of more accurate and elegant approximations for the mean, variance and skewness of the quasi-equilibrium distribution of the same model using cumulant truncation method. The method is extended for stochastic power law logistic family by the same and several other authors (Nasell, 2003; Singh and Hespanha, 2007). Cumulant truncation and some alternative methods e.g. saddle point approximation, derivative matching approach can be applied if the powers involved in the extended logistic set up are integers, although plenty of evidence is available for non-integer powers in many practical situations (Sibly et al., 2005). In this paper, we develop a set of new approximations for mean, variance and skewness of the quasi-equilibrium distribution under more general family of growth curves, which is applicable for both integer and non-integer powers. The deterministic counterpart of this family of models captures both monotonic and non-monotonic behavior of the per capita growth rate, of which theta-logistic is a special case. The approximations accurately estimate the first three order moments of the quasi-equilibrium distribution. The proposed method is illustrated with simulated data and real data from global population dynamics database.

  10. US - India Partnership in Science and Technology, Environment and Health: Opportunities and Challenges

    SciTech Connect

    Kulkarni, Satish V

    2010-10-06

    Today, the US – India strategic partnership is rooted in shared values and is broad in nature and scope, with our two countries working together on global and energy security, climate change and clean environment, life sciences and public health, economic prosperity and trade, and education. A key outcome of this partnership has been the signing of the historic Indo-US Civil Nuclear Deal. Science and technology (S&T) have always been important elements of this partnership, and US Secretary of State Condoleezza Rice and Indian S&T Minister Kapil Sibal signed an agreement on S&T Cooperation between the two countries in October 2005. In March 2006, recognizing the expanding role of S&T, President George Bush and Prime Minister Manmohan Singh formed a Bi-National S&T Commission and established a Joint S&T Endowment Fund focused on innovation, entrepreneurship and commercialization. In July 2009, US Secretary of State Hillary Clinton and Indian Foreign Minister Krishna signed the Endowment Agreement with a total equivalent funding of $30M (equal contribution from US and India). While these steps take our engagement to new heights, US-India collaboration in S&T is not new and has been ongoing for several decades, principally through agencies like NSF, NIH, EPA, DOE, NASA, NOAA, the PL480 US-India Fund, and the Indian Diaspora. However, acting as a damper, especially during the cold war days, this engagement has been plagued by sanctions and the resulting tensions and mistrust which continue to linger on even today. In this context, several ongoing activities in energy, space, climate change and education will be highlighted. Also, with the S&T and the Civil Nuclear Agreements and climate change as examples, the interplay of science, policy and politics will be discussed.

  11. Conformational preferences of a few enkephalin unsaturated analogs

    NASA Astrophysics Data System (ADS)

    Alagona, G.; Ciuffo, G. M.; Ghio, C.

    1994-07-01

    The conformational behavior of enkephalin analogs containing α-β unsaturated residues was studied employing a recent modification (G. Alagona, C. Ghio and C. Pratesi, J. Comput. Chem., 12 (1991) 934) of an existing force field for nucleic acids and proteins (S.J. Weiner, P.A. Kollman, D.A. Case, U. Chandra Singh, C. Ghio, G. Alagona, S. Profeta, Jr., and P. Weiner, J. Am. Chem. Soc., 106 (1984) 765) with molecular mechanics and molecular dynamics simulations. On the basis of the structures obtained, the rationale proposed for the morphine-like activity of enkephalins (i.e. the presence of β-turn of type II', considered important for the binding to opiate receptors) was checked and confirmed on the basis of topological features associated with a compact positioning of the aromatic side chains, tyrosine and phenylalanine or dehydrophenylalanine. The molecular electrostatic potential in the plane perpendicular to the α-β double bond may account only in part for the enhanced potency often observed in unsaturated compounds, and attributed to the intrinsic reactivity of the double bond toward nucleophilic sites on the opiate receptor or to a stronger binding to receptors. In the presence of the solvent, described as a continuous dielectric medium, most of the least stable conformations in vacuo are greatly stabilized, thus becoming even more favored than the gas-phase minimum-energy structures. Interestingly enough, the solvent stabilization is noticeable not only for the extended conformers, as expected, but also for several β-turn structures of type II'.

  12. Evaluation of different Diagnostic Modalities for Diagnosis of Dental Caries: An in vivo Study

    PubMed Central

    Somani, Rani; Jaidka, Shipra; Nishad, Muhamad; Singh, Shikha; Tomar, Divya

    2016-01-01

    Aim The aim of this study was to compare and evaluate the efficacy of different diagnostic aids for diagnosis of dental caries and to compare the validity in terms of sensitivity and specificity of all four diagnostic modalities for diagnosis of caries. Materials and methods Occlusal surfaces of 100 primary and permanent molars were examined using the four diagnostic systems (visual, intraoral camera, DIAGNOdent, and DIAGNOdent with dye). These results were compared with operative intervention gold standard. Sensitivity and specificity were calculated for each diagnostic system for both enamel and dentin caries. Interrater agreement was calculated for each diagnostic system using kappa statistics. Results For both enamel and dentin caries, the highest sensitivity values were provided by DIAGNOdent (0.91 and 0.72) and lowest for visual examination on wet surface (0.60 and 0.50). For both enamel and dentin caries, the specificity was found to be highest for intraoral camera on dry surface and lowest for visual examination. The DIAGNOdent gave the highest value of interrater agreement (kappa), i.e., 0.816 as compared with 0.03 for visual examination. Conclusion The study clearly demonstrated that DIAGNO-dent was the most accurate and valid system tested for the detection of occlusal caries. It has the advantage of quantifying the mineral content, helping to improve the diagnostic efficacy and treatment and accurate assessment of fissures where the visual examination alone is not adequate, thus complementing the traditional dental examination. How to cite this article Zaidi I, Somani R, Jaidka S, Nishad M, Singh S, Tomar D. Evaluation of different Diagnostic Modalities for Diagnosis of Dental Caries: An in vivo Study. Int J Clin Pediatr Dent 2016;9(4):320-325. PMID:28127163

  13. A forum: how big is the population factor?

    PubMed

    Sadik, N; Wattenberg, B J; Daly, H E; Commoner, B; Mchugh, J T; Singh, K

    1990-01-01

    6 protagonists responded to the issue of population growth and its likely ramifications: Nafis Sadik, Ben J. Wattenberg, Herman E. Daily, Barry Commoner, James T. McHugh, and Karan Singh. Sadik stated that at the current rate of growth the world's population could double in 40 years. In 1990 the total reached 5.3 billion with the addition of another 92 million people that year. At this rate the number could reach 6.25 billion by 2000, 8.5 billion by 2025, and 10-11 billion before leveling off around 2085 with 96% of this growth in the developing countries. The African rate of growth of 3-4% cancels out development programs. The present signs of environmental stress include the impairment of the ozone layer, acidification, depletion of rain forests, and erosion. According to Wattenberg the problem is not population, it is culture, what people do that makes the difference. In south Korea, Indonesia, India, China, Brazil, and Mexico there have been major decreased in fertility since the early 1960s. Free market opportunities with family planning offer the solution. Daly opined that affluence was the main environment problem. Poverty induces higher fertility and environmental degradation; the specter of the consumption level of the average Indian rising to the levels of the average Swede looms; thus the consumption of industrial countries must be reduced. Commoner declared that the demographic transition as it had occurred in developed countries explains population growth as a result of improved living conditions and reduced mortality before fertility plummets because of even higher living standards. The economies of developing countries must be strengthened to eliminate poverty whereby they can attain stable populations. Cooperation among nations, enhancement of human life and dignity, and intensified efforts to provide family planning were advocated by the others.

  14. Upper limit to magnetism in LaAlO3/SrTiO3 heterostructures

    NASA Astrophysics Data System (ADS)

    Fitzsimmons, Michael

    2012-02-01

    In 2004 Ohtomo and Hwang reported unusually high conductivity in LaAlO3 and SrTiO3 bilayer samples. Since then, metallic conduction, superconductivity, magnetism, and coexistence of superconductivity and ferromagnetism have been attributed to LaAlO3/SrTiO3 interfaces. Very recently, two studies have reported large magnetic moments attributed to interfaces from measurement techniques that are unable to distinguish between interfacial and bulk magnetism. Consequently, it is imperative to perform magnetic measurements that by being intrinsically sensitive to interface magnetism are impervious to experimental artifacts suffered by bulk measurements. Using polarized neutron reflectometry, we measured the neutron spin dependent reflectivity from four LaAlO3/SrTiO3 superlattices. Our results indicate the upper limit for the magnetization averaged over the lateral dimensions of the sample induced by an 11 T magnetic field at 1.7 K is less than 2 G. SQUID magnetometry of the neutron superlattice samples sporadically finds an enhanced moment (consistent with past reports), possibly due to experimental artifacts. These observations set important restrictions on theories which imply a strongly enhanced magnetism at the interface between LaAlO3 and SrTiO3. Work performed in collaboration with N.W. Hengartner, S. Singh, M. Zhernenkov (LANL), F.Y. Bruno, J. Santamaria (Universidad Complutense de Madrid), A. Brinkman, M.J.A. Huijben, H. Molegraaf (MESA+ Institute for Nanotechnology), J. de la Venta and Ivan K. Schuller (UCSD). [4pt] Work supported by the Office of Basic Energy Science, U.S. Department of Energy, BES-DMS and DMR under grant DE FG03-87ER-45332. Work at UCM is supported by Consolider Ingenio CSD2009-00013 (IMAGINE), CAM S2009-MAT 1756 (PHAMA) and work at Twente is supported by the Foundation for Fundamental Research on Matter (FOM).

  15. Integrated framework for the flux calculation of neutral species inside trenches and holes during plasma etching

    SciTech Connect

    Kokkoris, George; Boudouvis, Andreas G.; Gogolides, Evangelos

    2006-11-15

    An integrated framework for the neutral flux calculation inside trenches and holes during plasma etching is described, and a comparison between the two types of structure in a number of applications is presented. First, a detailed and functional set of equations for the neutral and ion flux calculations inside long trenches and holes with cylindrical symmetry is explicitly formulated. This set is based on early works [T. S. Cale and G. B. Raupp, J. Vac. Sci. Technol. B 8, 1242 (1990); V. K. Singh et al., J. Vac. Sci. Technol. B 10, 1091 (1992)], and includes new equations for the case of holes with cylindrical symmetry. Second, a method for the solution of the respective numerical task, i.e., one or a set of linear or nonlinear integral equations, is described. This method includes a coupling algorithm with a surface chemistry model and resolves the singularity problem of the integral equations. Third, the fluxes inside trenches and holes are compared. The flux from reemission is the major portion of the local flux at the bottom of both types of structure. The framework is applied in SiO{sub 2} etching by fluorocarbon plasmas to predict the increased intensity of reactive ion etching lag in SiO{sub 2} holes compared to trenches. It is also applied in deep Si etching: By calculating the flux of F atoms at the bottom of very high aspect ratio (up to 150) Si trenches and holes during the gas chopping process, the aspect ratio at which the flux of F atoms is eliminated and etching practically stops is estimated.

  16. Hypoxic preconditioning with cobalt attenuates hypobaric hypoxia-induced oxidative damage in rat lungs.

    PubMed

    Shukla, Dhananjay; Saxena, Saurabh; Jayamurthy, Purushotman; Sairam, Mustoori; Singh, Mrinalini; Jain, Swatantra Kumar; Bansal, Anju; Ilavazaghan, Govindaswamy

    2009-01-01

    Shukla, Dhananjay, Saurabh Saxena, Purushotman Jayamurthy, Mustoori Sairam, Mrinalini, Singh, Swatantra Kumar Jain, Anju Bansal, and Govindaswamy Ilavazaghan. High Alt. Med. Biol. 10:57-69, 2009.-Hypoxic preco759nditioning (HPC) provides robust protection against injury from subsequent prolonged hypobaric hypoxia, which is a characteristic of high altitude and is known to induce oxidative injury in lung by increasing the generation of reactive oxygen species (ROS) and decreasing the effectiveness of the antioxidant defense system. We hypothesize that HPC with cobalt might protect the lung from subsequent hypobaric hypoxia-induced lung injury. HPC with cobalt can be achieved by oral feeding of CoCl(2) (12.5 mg kg(-1)) in rats for 7 days. Nonpreconditioned rats responded to hypobaric hypoxia (7619 m) by increased reactive oxygen species (ROS) generation and a decreased GSH/GSSG ratio. They also showed a marked increase in lipid peroxidation, heat-shock proteins (HSP32, HSP70), metallothionins (MT), levels of inflammatory cytokines (TNF-alpha, IFN-gamma, MCP-1), and SOD, GPx, and GST enzyme activity. In contrast, rats preconditioned with cobalt were far less impaired by severe hypobaric hypoxia, as observed by decreased ROS generation, lipid peroxidation, and inflammatory cytokine release and an inceased GSH/GSSG ratio. Increased expression of antioxidative proeins Nrf-1, HSP-32, and MT was also observed in cobalt- preconditioned animals. A marked increase in the protein expression and DNA binding activity of hypoxia-inducible transcriptional factor (HIF-1alpha) and its regulated genes, such as erythropoietin (EPO) and glucose transporter-1 (glut-1), was observed after HPC with cobalt. We conclude that HPC with cobalt enhances antioxidant status in the lung and protects from subsequent hypobaric hypoxia-induced oxidative stress.

  17. Comparative Evaluation of Oral Candida albicans Carriage in Children with and without Dental Caries: A Microbiological in vivo Study

    PubMed Central

    Srivastava, Binita; Bhatia, Hind Pal; Aggarwal, Archana; Kumar Singh, Ashish; Gupta, Nidhi

    2012-01-01

    ABSTRACT Aim: The aim of this study was to examine the presence of Candida albicans in extensive carious lesions before and after treatment of the carious lesions and to evaluate the carriage of Candida albicans in children with and without caries. Materials and methods: The study was conducted on 60 childrens who were divided into two groups: Experimental group (group 1) and controlled group (group 2). Each group was further divided into 3 subgroups according to the dentition as: Group A (Deciduous), group B (Mixed) and group C (Permanent). Swab samples for mycological studies were collected from the dorsum of the tongue, vestibular sulcus and peak of the palatal vault. All samples were cultured directly on SDA plate (Sabouraud's dextrose agar). Number of Candida colonies was determined by counting colony forming unit on SDA plates. Further identification of Candida albicans was done by germ-tube test and corn-meal agar. Result: Overall prevalence of Candida albicans carriage was significantly higher and mean value of Candida albicans CFU (colony forming unit) was remarkably higher in group 1 (experimental group) as compare to group 2 (control group). Significant reduction in the frequency and mean value of Candida albicans CFU/plate was seen in children after treatment of carious lesions. Conclusion: This study supports the active role of Candida species in dental caries. Hence, Candida albicans may play an important role as a risk factor for dental caries. It was also seen that the oral environment stabilization procedures were able to reduce Candida albicans counts. Thus, these procedures can be considered efficient in the reduction of caries risk. How to cite this article: Srivastava B, Bhatia HP, Chaudhary V, Aggarwal A, Singh AK, Gupta N. Comparative Evaluation of Oral Candida albicans Carriage in Children with and without Dental Caries: A Microbiological in vivo Study. Int J Clin Pediatr Dent 2012;5(2):108-112. PMID:25206148

  18. THERMAL STRUCTURE OF CORONAL LOOPS AS SEEN WITH NORIKURA CORONAGRAPH

    SciTech Connect

    Prasad, S. Krishna; Singh, Jagdev; Ichimoto, K.

    2013-03-10

    The thermal structure of a coronal loop, both along and across the loop, is vital in determining the exact plasma heating mechanism. High-resolution spectroscopic observations of the off-limb corona were made using the 25 cm Norikura coronagraph, located at Norikura, Japan. Observations on a number of days were made simultaneously in four forbidden iron emission lines, namely, the [Fe XI] 7892 A line, the [Fe XIII] 10747 A and 10798 A lines, and the [Fe XIV] 5303 A line and on some days made only in the [Fe XI] 7892 A and [Fe X] 6374 A lines. Using temperature sensitive emission line ratios [Fe XIV] 5303 A/[Fe XIII] 10747 A and [Fe XI] 7892 A/[Fe X] 6374 A, we compute the electron temperatures along 18 different loop structures observed on different days. We find a significant negative temperature gradient in all of the structures observed in Fe XIV and Fe XIII and a positive temperature gradient in the structures observed in Fe XI and Fe X. Combining these results with the previous investigations by Singh and his collaborators, we infer that the loop tops, in general, appear hotter when observed in colder lines and colder when observed in relatively hotter lines as compared to their coronal foot points. We suggest that this contrasting trend observed in the temperature variation along the loop structures can be explained by a gradual interaction of different temperature plasma. The exact mechanism responsible for this interaction must be investigated further and has the potential to constrain loop heating models.

  19. Theory and Simulation of Extensional Flow-Induced Biaxiality in Discotic Mesophases

    NASA Astrophysics Data System (ADS)

    Singh, Arvinder P.; Rey, Alejandro D.

    1995-09-01

    Flow-induced biaxiality is simulated for a uniaxial discotic nematic liquid crystal subjected to a constant uniaxial, isothermal, incompressible, irrotational, extensional, three dimensional flow, using a previously presented model [Singh A.P. and Rey A.D., J. Phys. II France 4 (1994) 645]. Numerical and analytical solutions of the director triad (n, m, l), and uniaxial (S) and biaxial (P) alignments are given. The unit sphere description of the director triad is used to discuss and analyze the sensitivity of the director triad trajectories and the coupled alignment (uniaxial and biaxial) relaxations to the initial orientation, nematic potential (U), and to the alignment Deborah number (dimensionless extension rate). The evolution of the director triad is given by the rotation of a moving diad (n, l) around a fixed director (m). When the poles of the orientation unit sphere are along the extension axis, and the equator lies in the compression plane of the flow, it is found that the director diad (n, l) dynamics follow geodesic flow and the trajectories belong to the same meridians (great circles through the poles). The space of stable steady state orientation of the uniaxial director n and the biaxial director m is the whole compression plane (the equator of the unit sphere), while that of the biaxial director l is the extension direction (poles). A high degree extension flow-induced biaxiality is found when the uniaxial director is away from the extension axis and when S is relatively low. The scalar order parameter couplings are captured by analyzing the trajectories in the alignment triangle. Computed scientific visualizations of biaxial molecular orientation distributions are used to correlate the director triad dynamics and the alignment's dynamics. The tensor order parameter is used to calculate the main flow-birefringences, thus providing a direct way to verify the theoretical predictions of this paper.

  20. Assessment of Historic Trend in Mobility and Energy Use in India Transportation Sector Using Bottom-up Approach

    SciTech Connect

    Zhou, Nan; McNeil, Michael A.

    2009-05-01

    Transportation mobility in India has increased significantly in the past decades. From 1970 to 2000, motorized mobility (passenger-km) has risen by 888%, compared with an 88% population growth (Singh,2006). This contributed to many energy and environmental issues, and an energy strategy incorporates efficiency improvement and other measures needs to be designed. Unfortunately, existing energy data do not provide information on driving forces behind energy use and sometime show large inconsistencies. Many previous studies address only a single transportation mode such as passenger road travel; did not include comprehensive data collection or analysis has yet been done, or lack detail on energy demand by each mode and fuel mix. The current study will fill a considerable gap in current efforts, develop a data base on all transport modes including passenger air and water, and freight in order to facilitate the development of energy scenarios and assess significance of technology potential in a global climate change model. An extensive literature review and data collection has been done to establish the database with breakdown of mobility, intensity, distance, and fuel mix of all transportation modes. Energy consumption was estimated and compared with aggregated transport consumption reported in IEA India transportation energy data. Different scenarios were estimated based on different assumptions on freight road mobility. Based on the bottom-up analysis, we estimated that the energy consumption from 1990 to 2000 increased at an annual growth rate of 7% for the mid-range road freight growth case and 12% for the high road freight growth case corresponding to the scenarios in mobility, while the IEA data only shows a 1.7% growth rate in those years.

  1. Biological responses of agricultural soils to fly-ash amendment.

    PubMed

    Singh, Rajeev Pratap; Sharma, Bhavisha; Sarkar, Abhijit; Sengupta, Chandan; Singh, Pooja; Ibrahim, Mahamad Hakimi

    2014-01-01

    The volume of solid waste produced in the world is increasing annually, and disposing of such wastes is a growing problem. Fly ash (FA) is a form of solid waste that is derived from the combustion of coal. Research has shown that fly ash may be disposed of by using it to amend agricultural soils. This review addresses the feasibility of amending agricultural field soils with fly ash for the purpose of improvings oil health and enhancing the production of agricultural crops. The current annual production of major coal combustion residues (CCRs) is estimated to be -600 million worldwide, of which about 500 million t (70-80%) is FA (Ahmaruzzaman 2010). More than 112 million t of FA is generated annually in India alone, and projections show that the production (including both FA and bottom ash) may exceed 170 million t per annum by 2015 (Pandey et al. 2009; Pandey and Singh 20 I 0). Managing this industrial by-product is a big challenge, because more is produced each year, and disposal poses a growing environmental problem.Studies on FA clearly shows that its application as an amendment to agricultural soils can significantly improve soil quality, and produce higher soil fertility. What FA application method is best and what level of application is appropriate for any one soil depends on the following factors: type of soil treated, crop grown, the prevailing agro climatic condition and the character of the FA used. Although utilizing FA in agricultural soils may help address solid waste disposal problems and may enhance agricultural production, its use has potential adverse effects also. In particular, using it in agriculture may enhance amounts of radionuclides and heavy metals that reach soils, and may therefore increase organism exposures in some instances.

  2. Report on errors in pretransfusion testing from a tertiary care center: A step toward transfusion safety

    PubMed Central

    Sidhu, Meena; Meenia, Renu; Akhter, Naveen; Sawhney, Vijay; Irm, Yasmeen

    2016-01-01

    Introduction: Errors in the process of pretransfusion testing for blood transfusion can occur at any stage from collection of the sample to administration of the blood component. The present study was conducted to analyze the errors that threaten patients’ transfusion safety and actual harm/serious adverse events that occurred to the patients due to these errors. Materials and Methods: The prospective study was conducted in the Department Of Transfusion Medicine, Shri Maharaja Gulab Singh Hospital, Government Medical College, Jammu, India from January 2014 to December 2014 for a period of 1 year. Errors were defined as any deviation from established policies and standard operating procedures. A near-miss event was defined as those errors, which did not reach the patient. Location and time of occurrence of the events/errors were also noted. Results: A total of 32,672 requisitions for the transfusion of blood and blood components were received for typing and cross-matching. Out of these, 26,683 products were issued to the various clinical departments. A total of 2,229 errors were detected over a period of 1 year. Near-miss events constituted 53% of the errors and actual harmful events due to errors occurred in 0.26% of the patients. Sample labeling errors were 2.4%, inappropriate request for blood components 2%, and information on requisition forms not matching with that on the sample 1.5% of all the requisitions received were the most frequent errors in clinical services. In transfusion services, the most common event was accepting sample in error with the frequency of 0.5% of all requisitions. ABO incompatible hemolytic reactions were the most frequent harmful event with the frequency of 2.2/10,000 transfusions. Conclusion: Sample labeling, inappropriate request, and sample received in error were the most frequent high-risk errors. PMID:27011670

  3. A New Framework for Adaptive Sampling and Analysis During Long-Term Monitoring and Remedial Action Management

    SciTech Connect

    Minsker, Barbara

    2004-12-01

    The Argonne team has gathered available data on monitoring wells and measured hydraulic heads from the Argonne 317/319 site and sent it to UIUC. Xiaodong Li, a research assistant supported by the project, has reviewed the data and has fit initial spatiotemporal statistical models to it. Another research assistant, Yonas Demissie, has completed generation of the artificial data that will be used for model development and testing. In order to generate the artificial data a detailed groundwater flow and contaminant transport model was developed based upon characteristics of the 317/319 site. The model covers a multi-year time horizon that includes both before and after planting of the trees. As described in the proposal, the artificial data is created by adding ''measurement'' error to the ''true'' value from the numerical model. To date, only simple white noise error models have been considered. He is now reviewing the literature and beginning to develop a hierarchical modeling approach for the artificial data. Abhishek Singh, a third research assistant supported by the project, is implementing learning models for learning users preferences in an interactive genetic algorithm for solving the inverse problem. Meghna Babbar, the fourth research assistant supported by the project, has been improving the user interface for the interactive genetic algorithm and preparing a long-term monitoring design problem for testing the approach. Gayathri Gopalakrishnan, the last research assistant who is partially supported by the project, has collected substantial data from the 317/319 phytoremediation site at Argonne and has begun learning approaches for modeling these data.

  4. Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247

    PubMed Central

    Kirby, Karen A.; Ong, Yee Tsuey; Hachiya, Atsuko; Laughlin, Thomas G.; Chiang, Leslie A.; Pan, Yun; Moran, Jennifer L.; Marchand, Bruno; Singh, Kamalendra; Gallazzi, Fabio; Quinn, Thomas P.; Yoshimura, Kazuhisa; Murakami, Toshio; Matsushita, Shuzo; Sarafianos, Stefan G.

    2015-01-01

    Humanized monoclonal antibody KD-247 targets the Gly312-Pro313-Gly314-Arg315 arch of the third hypervariable (V3) loop of the HIV-1 surface glycoprotein. It potently neutralizes many HIV-1 clade B isolates, but not of other clades. To understand the molecular basis of this specificity, we solved a high-resolution (1.55 Å) crystal structure of the KD-247 antigen binding fragment and examined the potential interactions with various V3 loop targets. Unlike most antibodies, KD-247 appears to interact with its target primarily through light chain residues. Several of these interactions involve Arg315 of the V3 loop. To evaluate the role of light chain residues in the recognition of the V3 loop, we generated 20 variants of KD-247 single-chain variable fragments with mutations in the antigen-binding site. Purified proteins were assessed for V3 loop binding using AlphaScreen technology and for HIV-1 neutralization. Our data revealed that recognition of the clade-specificity defining residue Arg315 of the V3 loop is based on a network of interactions that involve TyrL32, TyrL92, and AsnL27d that directly interact with Arg315, thus elucidating the molecular interactions of KD-247 with its V3 loop target.—Kirby, K. A., Ong, Y. T., Hachiya, A., Laughlin, T. G., Chiang, L. A., Pan, Y., Moran, J. L., Marchand, B., Singh, K., Gallazzi, F., Quinn, T. P., Yoshimura, K., Murakami, T., Matsushita, S., Sarafianos, S. G. Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247. PMID:25351987

  5. A microswitch-cluster program to foster adaptive responses and head control in students with multiple disabilities: replication and validation assessment.

    PubMed

    Lancioni, Giulio E; Singh, Nirbhay N; O'Reilly, Mark F; Sigafoos, Jeff; Oliva, Doretta; Gatti, Michela; Manfredi, Francesco; Megna, Gianfranco; La Martire, Maria L; Tota, Alessia; Smaldone, Angela; Groeneweg, Jop

    2008-01-01

    A program relying on microswitch clusters (i.e., combinations of microswitches) and preferred stimuli was recently developed to foster adaptive responses and head control in persons with multiple disabilities. In the last version of this program, preferred stimuli (a) are scheduled for adaptive responses occurring in combination with head control (i.e., head upright) and (b) last through the scheduled time only if head control is maintained for that time. The first of the present two studies was aimed at replicating this program with three new participants with multiple disabilities adding to the three reported by Lancioni et al. [Lancioni, G. E., Singh, N. N., O'Reilly, M. F., Sigafoos, J., Didden, R., Oliva, D., et al. (2007). Fostering adaptive responses and head control in students with multiple disabilities through a microswitch-based program: Follow-up assessment and program revision. Research in Developmental Disabilities, 28, 187-196]. The second of the two studies served to carry out an expert validation of the program's effects on head control and general physical condition with the three participants of Study I as well as the three participants involved in the Lancioni et al. study mentioned above. The expert raters were 72 new physiotherapists and 72 experienced physiotherapists. The results of Study I supported previous data and indicated that the program was effective in helping the participants increase the frequency of adaptive responses in combination with head control and the length of such control. The results of Study II showed that the raters found the effects of the new program more positive than those of other intervention conditions and also considered such program a useful complement to formal motor rehabilitation programs.

  6. Suppression of superconductivity with Pr substitution in Nd 1- xPr xBaCaCu 3O 7 system

    NASA Astrophysics Data System (ADS)

    Awana, V. P. S.; Cardoso, Claudio A.; de Lima, O. F.; Singh, Rajvir; Narlikar, A. V.; Yelon, W. B.; Malik, S. K.

    1999-05-01

    The structural, superconducting and magnetic properties of Nd 1- xPr xBaCaCu 3O 7 system with x=0.0, 0.10, 0.25, 0.35, 0.50, 0.75 and 1.0 have been investigated. X-ray diffraction results reveal that Pr substitutes isostructurally in NdBaCaCu 3O 7 (Nd:1113) superconductor with complete solubility. The superconducting transition temperature ( Tc), measured by ac susceptibility technique, decreases with increasing x. However, suppression of Tc with increasing Pr substitution is less in Nd:1113 superconductor compared to that reported for Nd 1- xPr xBa 2Cu 3O 7 system. Interestingly, in the fully Pr substituted compounds of the above series, i.e., in PrBaCaCu 3O 7 and PrBa 2Cu 3O 7, the Pr moments order antiferromagnetically with TN of 10 and 17 K, respectively. The present results along those reported earlier [V.P.S. Awana, J. Horvat, S.X. Dou, A. Sedky, A.V. Narlikar, J. Magn. Magn. Mater., 182 (1998) L280; V.P.S. Awana, S.X. Dou, S.K. Malik, Rajvir Singh, A.V. Narlikar, D.A. Landinez Tellez, J.M. Ferreira, J. Albino Aguiar, S. Uma, E. Gmelin, W.B. Yelon, J. Magn. Magn. Mater., 187 (1998) 192], clearly suggest that there is a correlation between the Tc suppression due to Pr and the magnetic ordering temperature of the fully substituted Pr moments in these systems. The TN may be taken to be a measure of the strength of hybridization between the Pr-4f electrons with Cu-O conduction band, and hence a lower TN may imply a less deleterious effect on superconductivity.

  7. Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT.

    PubMed

    Noskov, Sergei Y

    2008-12-01

    The recently published X-ray structure of LeuT, a Na(+)/Cl(-)-dependent neurotransmitter transporter, has provided fresh impetus to efforts directed at understanding the molecular principles governing specific neurotransmitter transport. The combination of the LeuT crystal structure with the results of molecular simulations enables the functional data on specific binding and transport to be related to molecular structure. All-atom FEP and molecular dynamics (MD) simulations of LeuT embedded in an explicit membrane were performed alongside a decomposition analysis to dissect the molecular determinants of the substrate specificity of LeuT. It was found that the ligand must be in a zwitterionic (ZW) form to bind tightly to the transporter. The theoretical results on the absolute binding-free energies for leucine, alanine, and glycine show that alanine can be a potent substrate for LeuT, although leucine is preferred, which is consistent with the recent experimental data (Singh et al., Nature 2007;448:952-956). Furthermore, LeuT displays robust specificity for leucine over glycine. Interestingly, the ability of LeuT to discriminate between substrates relies on the dynamics of residues that form its binding pocket (e.g., F253 and Q250) and the charged side chains (R30-D404) from a second coordination shell. The water-mediated R30-D404 salt bridge is thought to be part of the extracellular (EC) gate of LeuT. The introduction of a polar ligand such as glycine to the water-depleted binding pocket of LeuT gives rise to structural rearrangements of the R30-D404-Q250 hydrogen-bonding network and leads to increased hydration of the binding pocket. Conformational changes associated with the broken hydrogen bond between Q250 and R30 are shown to be important for tight and selective ligand binding to LeuT.

  8. The inventions technology on water resources to support environmental engineering based infrastructure

    NASA Astrophysics Data System (ADS)

    Sunjoto, S.

    2017-03-01

    ), Singh (2000) etc. The advantages of Sunjoto's equation compared to the former methods that it is simpler in equation, easier to compute, doesn't need graphical support, is accurate in result and doesn't need observation well in pumping test, due to its need on drawdown on well function duration of pumping data only.

  9. Characteristics of hydrothermal convection in inclined layers: implications for hydrothermal activity at slow-spreading axis.

    NASA Astrophysics Data System (ADS)

    Fontaine, F. J.; Cannat, M.; Escartin, J.; Dusunur, D.

    2006-12-01

    The thermal structure of segments along (slow-spreading) mid-ocean ridges is likely to be a key parameter controlling the distribution, dynamics and geometry of hydrothermal systems. It is usually considered that the depth of penetration of hydrothermal fluids at the ridge axis is a function of the depth to the brittle-ductile transition. At slow-spreading axis, it is likely that this depth varies both along- and across-axis, with a deepening of several kilometers from the segment center towards its ends [e.g., Hooft et al., 2000]. This geometry is a consequence of focused melt supply to the segment center, resulting in the episodic and localized injection of magma bodies in the crust, as observed at the Lucky Strike segment of the Mid-Atlantic ridge [Singh et al., 2005]. In order to study the effect of such slopes of the basal temperature on the dynamics of slow-spreading axis hydrothermal systems, we ran a series of two-dimensional numerical models of hydrothermal convection. As a first approximation and following previous studies [e.g., Rabinowicz et al., 1999], we assume that these systems can be represented as rectangular and inclined permeable layers. The models are single-phase and incorporate realistic fluid properties and permeabilities. We have explored the cases of slopes ranging from 0 to 15°, aspect ratios from 1 to 16, and permeabilities up to 10^{-14} m2. The basal slope controls the number of convective cells. As the slope increases, the ratio of the size of the downflow and upflow areas increases. Above a critical slope the circulation is uni-cellular and composed of a broad recharge zone and a focused discharge zone, and encompassing the whole length of the segment. We will present the implication of our models for the distribution of vent sites along slow-spreading ridge segments. The segment-scale circulation and focused outflow obtained could also explain the elevated heat flux at some of the main sites found along slow-spreading ridges like

  10. Imaging Lithospheric Structure beneath the Indian continent

    NASA Astrophysics Data System (ADS)

    Maurya, S.; Montagner, J. P.; Mangalampally, R. K.; Stutzmann, E.; Burgos, G.; Kumar, P.; Davuluri, S.

    2015-12-01

    The lithospheric structure and thickness to the LAB are the most debated issues, especially beneath continents. In this context, the structure and thickness of the Indian lithosphere has been controversial. Paleomagnetic data reveals that the Indian continent moved northwards at exceptionally high speeds (18-20 cm/year) and subsequently slowed down to 4-5 cm/year after its collision with Asia ≈40 Myr ago. This super mobility has been explained by an unusually thin Indian lithosphere (≈100 km; Kumar et al., 2007) in contradiction with the thick lithosphere that commonly underlies old cratonic nuclei. It is pertinent to note that the thermobarometric estimates on the ultramafic xenoliths from 65 Myr kimberlites of the Central India (Babu et al. 2009) suggest an approximately 175 km thick lithosphere. Also, recent results of P and S wave travel time tomography of India suggest that the lithospheric roots are not uniformly thick on a regional scale. Although high velocity roots typical of Precambrian shields are preserved beneath a few cratons of the Indian shield, they seem to have suffered attrition, in the plume ravaged regions like the NDVP and the Southern SGT (Singh et al., 2014). We assembled a new massive surface wave database towards obtaining 3D isotropic and anisotropic models for the Indian sub-continent, using surface waves. This necessitated processing of data from more than 500 seismic broadband stations across India and surrounding regions. Surface waves group and phase dispersion measurements are performed in a broad frequency range (16-250s). Our phase velocity anomaly maps recover most of the known geological structures. The cratons are associated with high velocity (4-6%) anomalies till 200 sec, with the WDC being faster than the EDC. Slow velocities in NW India and very high velocity anomalies (6-8%) beneath the central part of the Indo-Gangetic plains are possibly associated with the subducting Indian lithosphere. The LAB depths inferred from

  11. Porosity of Bleb Capsule declines rapidly with Fluid Challenge

    PubMed Central

    Pandav, Surinder S; Ross, Craig M; Thattaruthody, Faisal; Nada, Ritambhra; Singh, Nirbhai; Gautam, Natasha; Beirne, Stephen; Wallace, Gordon G; Sherwood, Mark B; Crowston, Jonathan G

    2016-01-01

    Introduction The porosity of the fibrous capsule around a glaucoma drainage device (GDD) may be the most important functional attribute. The factors that determine capsular porosity are not well understood. Failed GDD surgeries are usually associated with thick impervious capsules and components of aqueous have been implicated in this process. Purpose In this study, we interrogated the effect of passage of nonaqueous fluid on capsular porosity in mature (but aqueous naïve) blebs in a previously reported GDD model (the “Center for Eye Research Australia Implant”). Materials and methods The study was performed at two centers using 17 New Zealand White (NZW) rabbits. An experimental GDD was implanted into the subconjunctival space but without connection to the anterior chamber. After 28 days, balanced salt solution (BSS) was passed through the implant for 30 to 40 minutes at 12 mm Hg. Capsular porosity was measured as flow (μL/min) at a constant pressure. Porosity of the capsule was retested at 3 and 6 days. Results There was a marked reduction in capsular porosity within 3 days of exposure to BSS (fluid challenge). Even though the baseline porosity was significantly different in the two groups (3.00 ± 0.5 μL/min and 29.67 ± 12.12 μL/min, p < 0.001), the effect of passage of BSS was similar. Capsular porosity fell by approximately 80% in both groups from baseline after single BSS challenge. Capsular thickness was significantly less in Advanced Eye Center (AEC) rabbits at baseline. There was no change in the capsular thickness before and after single fluid challenge. Conclusion Passage of BSS at physiological pressures for under 40 minutes caused marked reduction in the porosity of the fibrous capsule within 3 days. This was not associated with any significant thickening of the fibrous capsule within this time frame. How to cite this article Pandav SS, Ross CM, Thattaruthody F, Nada R, Singh N, Gautam N, Beirne S, Wallace GG, Sherwood MB, Crowston JG, Coote M

  12. Add-on fluvoxamine treatment for schizophrenia: an updated meta-analysis of randomized controlled trials.

    PubMed

    Kishi, Taro; Hirota, Tomoya; Iwata, Nakao

    2013-12-01

    We performed an updated meta-analysis of fluvoxamine add-on therapy in patients with schizophrenia treated with antipsychotics based on two previous meta-analyses (Sepehry et al., in J Clin Psychiatry 68:604-610, 2007 and Singh et al., in Br J Psychiatry J Mental Sci 197:174-179, 2010). We searched PubMed, the Cochrane Library database, and PsycINFO up to January 2013. We conducted a systematic review and meta-analysis of individual patient data from randomized controlled trials comparing fluvoxamine add-on therapy with placebo. The risk ratio (RR), 95 % confidence intervals (CI), and standardized mean difference (SMD) were calculated. Seven studies (total n = 272) were identified. These included two clozapine studies, one olanzapine study, one second-generation antipsychotic (SGA) monotherapy study, and three first-generation antipsychotics (FGAs) monotherapy studies. There were significant effect of fluvoxamine add-on therapy on overall (SMD = -0.46, CI = -0.75 to -0.16, p = 0.003, I (2) = 0 %, 5 studies, n = 180) and negative symptoms (SMD = -0.44, CI = -0.74 to -0.14, p = 0.004, I (2) = 0 %, 5 studies, n = 180). However, fluvoxamine add-on therapy showed no significant effects on positive symptoms, depressive symptoms, and discontinuations from any cause or adverse events. Fluvoxamine add-on therapy in patients primarily treated with SGAs improved overall (p = 0.02) but not negative symptoms (p = 0.31). On the other hand, fluvoxamine add-on therapy in patients primarily treated with FGAs improved both overall (p = 0.04) and negative symptoms (p = 0.004) compared with control groups. Our results suggest that fluvoxamine add-on therapy is more beneficial on the psychopathology (especially negative symptoms) than controls in patients with schizophrenia who are primarily treated with FGAs. Given that a small number of studies were included in this meta-analysis, the results should be treated with caution.

  13. Laser Spectroscopic Study of CaH in the B^2σ^+ and D^2σ^+ States

    NASA Astrophysics Data System (ADS)

    Watanabe, Kyohei; Uchida, Kanako; Kobayashi, Kaori; Matsushima, Fusakazu; Moriwaki, Yoshiki

    2015-06-01

    Calcium hydride is one of the abundant molecules in the stellar environment, and is considered as a probe of stellar analysis. Ab initio calculations have shown that the electronic excited states of CaH have complex potential curves. It is suggested that the B^2σ^+ state has an interesting double minimum potential due to the avoided crossing. Such a potential leads to drastic change of the rotational constants when the vibrational energy level goes across the potential barrier. Spectroscopic studies on CaH began in the 1920's, and many studies have been carried out since then. Bell et al. extensively assigned the D^2σ^+-X^2σ^+ bands in the UV region. Bernath's group has observed transitions in the IR and visible regions and identified their upper states as the A^2σ^+, B^2σ^+ and E^2σ^+ states. We have carried out a laser induced fluorescence (LIF) study in the UV region between 360 and 430 nm. We have produced CaH by using laser ablation of a calcium target in a hydrogen gas environment, then molecules have been excited by a second harmonic pulse of dye laser and the fluorescence from molecules have been detected through a monochromator. Detection of the D^2σ^+-X^2σ^+ bands already identified by Bell et al. indicates the production of CaH. In addition, many other bands have been also found and a few bands have been assigned by using the combination differences, the lower state of these bands have been confirmed to the vibrational ground state of X^2σ^+ state. We have tentatively assigned these bands as the B^2σ^+ -X^2σ^+ transition. We will discuss the assignment of these bands, together with the rotational constants comparing with those calculated from the ab initio potential. B. Barbuy, R. P. Schiavon, J. Gregorio-Hetem, P. D. Singh C. Batalha , Astron. Astrophys. Sippl. Ser. 101, 409 (1993). P. F. Weck and P. C .Stabcil, J. Chem. Phys. {118}, 9997 (2003). R. S. Mulliken, Phys. Rev. {25}, 509 (1925). G. D. Bell, M, Herman, J. W. C. Johns, and E. R

  14. Crystal chemical aspects of superconductivity in BaFe2As2 and related compounds

    NASA Astrophysics Data System (ADS)

    Johrendt, Dirk

    2010-03-01

    BaFe2As2 is the parent compound of the 122-type iron arsenides.^1 Superconductivity can be induced by several kinds of doping^2-4 or by pressure.^5 It is widely accepted that superconductivity in iron arsenides is unconventional and a number of experiments agree with the s±-scenario.^6 The latter relies on Fermi surface nesting which depends on both the electron count and the lattice. However, the coincidence of doping and pressure effects on the structure of BaFe2As2 supports the role of the structure.^7 Another open issue is the co-existence of superconductivity and AF magnetic ordering. Our ^57Fe-M"ossbauer experiments with underdoped Ba0.8K0.2Fe2As2 (Tc = 24 K) revealed full magnetic splitting, which indicates such a co-existence.^8 Compounds like Sr2VO3FeAs (Tc = 37-45 K) are promising candidates for higher Tc, but their crystal chemistry is not yet understood. In non-superconducting Sr2CrO3FeAs, we have detected a non-stoichiometry of the Fe-site (Fe0.93(1)Cr0.07(1)) and C-type AF ordering of the Cr^3+-layers.^9 The Cr-doping of the FeAs layer is probably detrimental to superconductivity in Sr2CrO3FeAs, but a similar non-stoichiometry may play a vital role in Sr2VO3FeAs.-^1 M. Rotter, M. Tegel, I. Schellenberg, et al., Phys. Rev. B 78, 020503 (2008).^2 M. Rotter, M. Tegel, and D. Johrendt, Phys. Rev. Lett. 101, 107006 (2008).^3 S. Jiang, C. Wang, Z. Ren, et al., J. Phys.: Condens. Matter 21, 382203 (2009).^4 A. S. Sefat, R. Jin, M. A. McGuire, et al., Phys. Rev. Lett. 101, 117004 (2008).^5 P. L. Alireza, Y. T. C. Ko, J. Gillett, et al., J. Phys.: Condens. Matter 21, 012208 (2009).^6 I. Mazin, D. J. Singh, M. D. Johannes, et al., Phys. Rev. Lett. 101, 057003 (2008).^7 M. Rotter, M. Pangerl, M. Tegel, et al., Angew. Chem. Int. Ed. 47, 7949 (2008).^8 M. Rotter, M. Tegel, I. Schellenberg, et al., New J. Phys. 11, 025014 (2009).^9 M. Tegel, Y. Su, F. Hummel, et al., arXiv0911.0450.

  15. Regional Precipitation Forecast with Atmospheric InfraRed Sounder (AIRS) Profile Assimilation

    NASA Technical Reports Server (NTRS)

    Chou, S.-H.; Zavodsky, B. T.; Jedloved, G. J.

    2010-01-01

    Advanced technology in hyperspectral sensors such as the Atmospheric InfraRed Sounder (AIRS; Aumann et al. 2003) on NASA's polar orbiting Aqua satellite retrieve higher vertical resolution thermodynamic profiles than their predecessors due to increased spectral resolution. Although these capabilities do not replace the robust vertical resolution provided by radiosondes, they can serve as a complement to radiosondes in both space and time. These retrieved soundings can have a significant impact on weather forecasts if properly assimilated into prediction models. Several recent studies have evaluated the performance of specific operational weather forecast models when AIRS data are included in the assimilation process. LeMarshall et al. (2006) concluded that AIRS radiances significantly improved 500 hPa anomaly correlations in medium-range forecasts of the Global Forecast System (GFS) model. McCarty et al. (2009) demonstrated similar forecast improvement in 0-48 hour forecasts in an offline version of the operational North American Mesoscale (NAM) model when AIRS radiances were assimilated at the regional scale. Reale et al. (2008) showed improvements to Northern Hemisphere 500 hPa height anomaly correlations in NASA's Goddard Earth Observing System Model, Version 5 (GEOS-5) global system with the inclusion of partly cloudy AIRS temperature profiles. Singh et al. (2008) assimilated AIRS temperature and moisture profiles into a regional modeling system for a study of a heavy rainfall event during the summer monsoon season in Mumbai, India. This paper describes an approach to assimilate AIRS temperature and moisture profiles into a regional configuration of the Advanced Research Weather Research and Forecasting (WRF-ARW) model using its three-dimensional variational (3DVAR) assimilation system (WRF-Var; Barker et al. 2004). Section 2 describes the AIRS instrument and how the quality indicators are used to intelligently select the highest-quality data for assimilation

  16. Study of Ionosphere-Magnetosphere Coupling Using Whistler Data (P51)

    NASA Astrophysics Data System (ADS)

    Singh, S.; Singh, R. P.; Singh, L.

    2006-11-01

    singh_shubha@yahoo.co.in singhshubhadhu@gmail.com The VLF waves observed at the ground stations are used for probing the ionosphere/magnetosphere parameters. The probing principle depends on the analysis of dispersion produced in the whistler mode waves during their propagation from the source to the observation point. Dispersion depends on the distribution of plasma particles and ambient magnetic field along the path of propagation. Specifically, we derive the information about the equatorial electron density, total electron content in a flux tube, equatorial east-west electric field, transport of electron flux from one region to the other, electron temperature etc. The transport of flux and electric fields are essentially involved in the study of coupling of the ionosphere and magnetosphere. In the present paper, we shall report the analysis of whistler data recorded at Varanasi and Jammu. The analysis shows that the analyzed whistlers from both the stations belong to mid-high latitudes contrary to the belief that they were low latitude phenomena. Further, there is no correspondence between the dispersion and derived L-value for the path of propagation. This leads to the requirement of detailed study of VLF wave propagation in the inhomogeneous ionosphere-magnetosphere system. The electron density and the total electron content in a flux tube derived from whistler measurements at Varanasi and Jammu are approximately one order of magnitude smaller than the previously reported data from the whistler measurements at mid- high latitudes. However, their variation with L-value has the same nature. The time development of the content of flux is evaluated which could easily explain the reported flux transport during the study of coupling of ionosphere to the magnetosphere. We have also evaluated electric field, which compares well with the previously reported value. These results clearly indicate that the VLF wave propagation at low latitude and their diagnostic

  17. Name Recognition to Identify Patients of South Asian Ethnicity within the Cancer Registry

    PubMed Central

    Singh-Carlson, Savitri; Wong, Frances; Oshan, Gurpreet; Lail, Harajit

    2016-01-01

    Objective: The goal of this project was to develop a list of forenames and surnames of South Asian (SA) women that could be used to identify SA breast cancer patients within the cancer registry. This list was compiled, evaluated, and validated to ensure comprehensiveness, accuracy, and applicability of SA names. Methods: This project was conducted by Canadian researchers who are immersed in conducting behavioral studies with SA women diagnosed with cancer in the province of British Columbia. Recruiting SA cancer patients for research can be a difficult task due to social and cultural factors. Methods used by other researchers to identify ethnicity related unique names were employed to filter surnames and forenames that were not common to this ethnic group. Co-author (Gurpreet Oshan) of SA ethnicity rigorously identified and deleted multiple lists and redundant entries along with common English forenames which resulted in a list of 16,888 SA forenames. All co-authors of Indian ethnicity (Gurpreet Oshan, Savitri Singh-Carlson, Harajit Lail) were involved in critiquing and manually reviewing the names list throughout this process. Comprehensive lists of SA surnames and women's forenames were reviewed to identify those that were unique to SA ethnicity. Accuracy was ensured by constantly filtering the redundancy by using an Excel program which helped to illustrate the number of times each name was spelled in different ways. Results: The final lists included 9112 surnames and 16,888 forenames of SA ethnicity. On the basis of the surname linkage only, the sensitivity of the list was 76.6%, specificity was 62.9%, and the positive predictive value was 58.5%. On the basis of both the surname and forename linkage, the specificity of the list was 88.6%. These lists include variations in spelling forenames and surnames as well. Conclusions: The list of surnames and forenames can be useful tools to identify SA ethnic groups from large population database in healthcare

  18. Climate change effects on Glacier recession in Himalayas using Multitemporal SAR data and Automatic Weather Station observations

    NASA Astrophysics Data System (ADS)

    Kumar, V.; Singh, S. K.; Venkataraman, G.

    2009-04-01

    Hahadur, The Himalayas: A Third Polar Region, Snow and Glacier Hydrology (Proceedings of the Kathmandu Symposium, November 1992). IAHSPubl.no. 218,1993. 2.A. Paul, Mayewski and Peter, Jeschke A., Himalayan and Trans-Himalayan Glacier Fluctuations Since AD 1812, Arctic and Alpine Research, Vol. 11, No. 3, pp. 267-287 1979) 3.Tazio Strozzi, Adrian Luckman, Tavi Murray, Urs Wegmüller, and Charles L. Werner, IEEE Transaction on Geoscience and Remote Sensing, Vol. 40, NO. 11, November 2002 4.Vijay Kumar, Y.S.Rao, Gulab Singh G.Venkataraman, Snehmani , "Spaceborne InSAR technique for study of Himalayan glaciers using ENVISAT ASAR and ERS data", Proc. IGARSS 2008, July 6-11, 2008 Bostan, USA,2008.

  19. Seismotectonic Analysis for the KZN region of South Africa

    NASA Astrophysics Data System (ADS)

    Singh, M.

    2012-04-01

    model element will be explored in further detail for this research. Preliminary investigations into a seismotectonic investigation for the province have been undertaken by Singh et al. (2011). Under the framework of this research the following tasks are planned for the KZN coastal region: i) Development of a historical earthquake catalogue ii) Development of a GeoDatabase for Seismotectonic Zonation iii) Development of a Seismotectonic Model and iv) Development of an Earthquake Recurrence Model. The author will present progress made to date towards this research.

  20. Influences of Forest Tree Species and Early Spring Temperature on Surface-Atmosphere Transfers of Water and Carbon in the Northeastern U.S.

    NASA Astrophysics Data System (ADS)

    Hadley, J. L.; Kuzeja, P.; Mulcahy, T.; Singh, S.

    2008-12-01

    Influences of Forest Tree Species and Early Spring Temperature on Surface-Atmosphere Transfers of Water and Carbon in the Northeastern U.S. Julian Hadley, Paul Kuzeja, Safina Singh and Thomas Mulcahy Transfers of water vapor from terrestrial ecosystems to the atmosphere affect regional hydrology, weather and climate over short time scales, and forest-atmosphere CO2 exchange affects global climate over long timescales. To better understand these effects for forests dominated by two very different tree species, we measured forest-atmosphere water vapor and CO2 transfers by the eddy flux technique to at two sites in central Massachusetts USA for three years. Average annual evapotranspiration (ET) for a young deciduous forest dominated by red oak (Quercus rubra L., the most abundant tree species in the area), was about 430 mm or 25 percent greater than for a coniferous forest dominated by 100 to 230 year old eastern hemlock (Tsuga canadensis L.). The difference in ET was most pronounced in July and August when the deciduous forest lost about 50 percent more water by ET in the average year (192 mm for oak forest versus 130 mm for hemlock). These data indicate that if deciduous trees with similar physiology to red oak replace hemlocks, summertime ET will increase while summer streamflow, soil water content and the extent of year- round wetlands will decrease. Increased summertime ET should also lead to slightly higher regional atmospheric humidity and precipitation. Hemlock-to-deciduous forest conversion has occurred from North Carolina to southern New England and is continuing northward as a lethal insect pest, the hemlock woolly adelgid (Adelges tsugae Annand) continues to kill hemlocks. Average annual carbon storage for the old hemlock forest in our study was about 3.3 Mg C/ha, nearly equal to the average for the deciduous forest, 3.5 Mg C/ha. This calls into question ecological theory that predicts large declines in the rate of carbon uptake for old forests, and