Science.gov

Sample records for bibliothque scientifique nationale

  1. Café Scientifique.

    PubMed

    Grand, Ann

    2014-01-01

    Every month, in 700 or so bars, cafés, pubs, teahouses, shopping centres, community halls, art galleries, libraries, theatres, museums, bookshops ... and a blood donation centre, 40 or so people meet to have a conversation. A conversation that happens to be about science and technology, rather than soap operas or football; this is Café Scientifique.

  2. A Cafe Scientifique for Teens

    NASA Astrophysics Data System (ADS)

    Hall, M.; Mayhew, M.

    2008-12-01

    It is well-known to those pursuing the quest to connect scientists to the public that an exceedingly hard-to- reach demographic is people of high school age. Typically, kids may tag along with their parents to museums until they reach adolescence, and then don't again appear in museums until they themselves have children. We have addressed this demographic challenge for free-choice-learning by developing a Cafe Scientifique program specifically for high school students. The Cafe Scientifique model for adults was developed in England and France, and has now spread like wildfire across the U.S. Typically, people come to a informal setting like a cafe, socialize and have food and drink, and then hear a short presentation by a scientist on a hot science topic in the news. This is followed by a period of lively discussion. We have followed this model for high school age students in four towns in northern New Mexico--Los Alamos, Santa Fe, Espanola, and Albuquerque--which represent a highly diverse demographic. We started this novel project with some trepidation, i.e. what if we build it and they don't come. But the program has proven popular beyond our expectations in all four towns. A part of the secret of success is the social setting, and-especially for this age group-the food provided. But we have also found that the kids are genuinely interested in the science topics, directing their own program, and interacting with scientists. We have often heard statements like, "I think it is important to be well-informed citizens". One of the most important aspects of the Cafes for the kids is to be able to discuss and argue about issues related to the science topic with the presenter and each other. It is an important part of the popularity that the Cafes do not involve school or parents, but also that we have strived to give the kids ownership of the program. Each town has a Youth Leadership Team-open to any teen-that discusses and prioritizes potential topics, conducts

  3. Le matérialisme scientifique

    NASA Astrophysics Data System (ADS)

    Meunier, Jean-François

    2004-03-01

    De nos jours, il arrive quotidiennement aux grands hommes d'avoir à fréquenter d'ignorants mortels épris d'une conviction maladive que la science est la grande responsable de tous les maux du monde. Évidemment sans physique atomique, il n'y aurait pas eu d'Hiroshima et sans révolution industrielle, pas de pollution et etc. Cependant, ces accusations envers le progrès technique sont tout à fait injustes, irréfléchies et, j'irai même jusqu'à dire, irresponsables, puisque le calcul, i.e. la planification, même la plus élémentaire, est ce qui caractérise le mieux, pragmatiquement, la société humaine. À mon avis, les problèmes sociaux tireraient plutôt leur origine de sciences sociales irréalistes, qui, concrètment, inspireraient ou serviraient d'alibis à ceux qui détiennent véritablement le pouvoir. Dans cet article, je tenterai donc de démontrer la meilleure véracité et efficacité du matérialisme scientifique. Cette doctrine, dont Mario Bunge est le plus illustre représentant, s'appuy sur les résultats théoriques et expérimentaux des sciences factuelles ainsi que sur l'exactitude logique des mathématiques, utilisées ici comme langage universel de l'expression des idées. Cette conception philosophique qui s'inspire principalement du modèle des théories physiques, stipule que les réalités sociales sont, comme tout autre réalité, matérielles, mathématisables et représentables comme des systèmes en interaction. En fait, le modèle des physiciens ayant historiquement fait ses preuves en matière de testabilité et de cohérence interne est proposé d'être appliquer aux sciences sociales, aujourd'hui scindées des sciences dites pures sous l'inspiration des pseudo penseurs néo-kantiens, phénoménologiques et post-moderne. Cette nouvelle approche permettrait ainsi d'évoluer plus exactement vers une compréhension des bases sociales et biologiques du comportement humain afin de développer une éthique sans cesse plus r

  4. The game of science: A grounded theory of the Cafe Scientifique experience

    NASA Astrophysics Data System (ADS)

    Rabe, Lisa A.

    Science Cafes are independent groups organized throughout the world for discussion of scientific topics. Little is known about the nature of this informal learning environment. A grounded-theory study was conducted to determine what attendees perceived as the essential qualities of the Cafe Scientifique experience in one science Cafe in the Western United States. Interviews with 12 attendees were transcribed and analyzed using ATLAS-ti. Concept maps and a grounded theory describing the essential characteristics were created. Member checking was used during theory generation. Findings are described in the context of a game metaphor, whereby scientific discussion at the Cafe is viewed as an intellectual game. The grounded theory describes the game of science being played at Cafe Scientifique involving attendees as players, social norms as rules for the game, an expert as the steward of truth, topics as the content for game play, interaction as playing of the game, and intellectual stimulation as the prize for playing. During the game, ideas were identified through a short presentation followed by a question-and-answer session. During this exchange, attendees heard about, analyzed, synthesized, and applied new information. As a result of the game play, players won a prize---intellectual stimulation. The Cafe Scientifique phenomenon provides insight into informal adult education. This study suggests the need for additional study of intellectual play in adult education, the role of curiosity and desire to explore new ways of thinking, and the developmental drive in adults to seek intellectual stimulation. The essential characteristics of Cafe Scientifique may be transferable to other informal adult-education settings.

  5. Engaging High School Students and Scientists in a Café Scientifique Program

    NASA Astrophysics Data System (ADS)

    Mayhew, M. A.; Hall, M. K.; Foutz, S.

    2010-12-01

    We have created an informal science program that engages high school age youth in exploring science relevant to their lives with researchers working at the cutting edge of science. The program provides scientists a challenging new audience to share their research and enthusiasm for science and science careers. It gives the youth an opportunity to discover how the often-mundane science they are learning in school is used to push the frontiers in science, with exciting applications in the real world. Our program, a youth-led Café Scientifique (cafenm.org), now in its fourth year, has been successful in attracting and retaining youth as well as attracting scientist-presenters. Modeled after the international Café Scientifique program for adults, we combine a social atmosphere with discussion of controversial or current topics to challenge youth to think about how science affects their lives. We feature short presentations with a high degree of interactivity and discussion during which the scientist expert communicates a single important idea or scientific principle. A good speaker will leave the audience with a dilemma or controversy to discuss, and with further opportunities to learn. Encouraging the presenters to interact frequently with the audience allows them to gauge the audience's engagement and knowledge. Alternatively we also host Cafés that offer more hands-on learning experiences, including extracting DNA from plants, building model fuel cell cars, using Google Earth to spy, and deciphering age, gender, ethnicity, and cause of death from human skeletons. Controversial topics are often presented within a scientific, economic, and social or political framework, because science is only part of the solution. A key element of success is in preparing the presenters for the youth audience. Presenters submit their presentation to the program directors for initial review and receive feedback on length, mechanisms for involving the audience, and clarifying or

  6. [The German addendum to Hildegard von Bingen's 'Liber simplicis medicinae' in Codex 6952 of the Bibliothèque Nationale in Paris (fol. 232v-238v)].

    PubMed

    Adamson, M W

    1995-01-01

    The article contains an analysis and edition of the German appendix to Hildegard of Bingen's 'Liber simplicis medicinae' ('LSM', also known as 'Physica') in Codex 6952 of the Bibliothèque Nationale in Paris. Surprisingly, the German text is not based on the preceding Latin treatise, but on another unknown version of the 'LSM' which is closer to the archetype. The appendix thus has to be regarded as a new manuscript find, which also contains material found only in Hildegard's 'Liber compositae medicinae' ('LCM', also known as 'Causae et Curae'). This suggests that the translator had access to both texts, or that both once circulated as one treatise. In the reception of Hildegard's work, the 13-page German appendix is unique in that Hildegard's description of nature is transformed into three different types of medical writing: 1) a herbal, 2) a catalogue of diseases from head to toe and their remedies, and 3) a dietetic list of foodstuffs. To illustrate the technique applied by the compiler/translator, the edition of the Paris-appendix identifies all the quotes from the 'LSM' and 'LCM' which have so far been uncovered.

  7. Effets potentiels d’un modèle rationnel de prescription sur les dépenses nationales en santé

    PubMed Central

    Littman, Jordan; Halil, Roland

    2016-01-01

    Résumé Objectif Estimer les économies que pourrait engendrer la mise en œuvre d’un modèle rationnel de prescription pour des classes de médicaments équivalents sur les plans de l’efficacité, de la toxicité et de la commodité. Conception L’Institut canadien d’information sur la santé a fourni des renseignements sur les 10 principales classes de médicaments en fonction des dépenses annuelles qui leur sont attribuables. Ces classes ont été examinées en vue de leur inclusion potentielle dans l’étude selon qu’il était possible de comparer les médicaments à l’intérieur d’une même classe. Lorsqu’à la suite d’une recherche documentaire, une équivalence a été établie en fonction de l’efficacité, de la toxicité et de la commodité des médicaments, les données annuelles sur les prescriptions ont été recueillies à partir de la base de données du Système national d’information sur l’utilisation des médicaments prescrits. Les économies potentielles de coûts ont ensuite été calculées en comparant les parts de marché actuelles avec les parts potentielles futures de ce marché. Contexte Le Canada. Principaux paramètres à l’étude Les différences estimées dans les dépenses que produirait un modèle rationnel de prescription. Résultats Une équivalence a été établie sur les plans de l’efficacité, de la toxicité et de la commodité dans les classes de statines, d’inhibiteurs de la pompe à protons, d’inhibiteurs de l’enzyme de conversion de l’angiotensine et d’inhibiteurs sélectifs du recaptage de l’angiotensine. Les dépenses annuelles totales dans ces classes se situent à 856 millions $ dans les programmes publics de médicaments et à 1,97 milliard $ environ à l’échelle nationale. Grâce à des prescriptions rationnelles, on estime que les économies annuelles pourraient atteindre 222 millions $ pour les programmes publics et 521 millions $ à l’échelle nationale. Conclusion La

  8. Low risk of nevirapine resistance mutations in the prevention of mother-to-child transmission of HIV-1: Agence Nationale de Recherches sur le SIDA Ditrame Plus, Abidjan, Cote d'Ivoire.

    PubMed

    Chaix, Marie-Laure; Ekouevi, Didier Koumavi; Rouet, Francois; Tonwe-Gold, Besigin; Viho, Ida; Bequet, Laurence; Peytavin, Gilles; Toure, Hassane; Menan, Herve; Leroy, Valeriane; Dabis, Francois; Rouzioux, Christine

    2006-02-15

    The frequency of resistance mutations was estimated in the cohort of Agence Nationale de Recherches sur le SIDA Ditrame Plus, a study that evaluated the combination of short-course zidovudine (ZDV) plus lamivudine (3TC) and single-dose nevirapine (SD-NVP) followed by 3 days of postpartum ZDV plus 3TC for the prevention of mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1). The frequency with which resistance mutations were detected in mothers at week 4 postpartum was 1.14% (95% confidence interval [CI], 0.03%-6.17%) for NVP and 8.33% (95% CI, 3.66%-15.76%) for 3TC. In multivariate analysis, 3TC resistance was associated with a longer duration of ZDV plus 3TC prepartum prophylaxis (P=.009). This regimen, which is feasible in resource-limited settings, prevents most peripartum HIV-1 transmission and minimizes the development of NVP resistance.

  9. Profil de la néphropathie diabétique à l’Hôpital Général de Référence Nationale de N'Djamena (Tchad)

    PubMed Central

    Hamat, Ibrahim; Abderraman, Guillaume Mahamat; Cisse, Mouhamadou Moustapha; Youssouf, Mahamat; Djafar, Matar Saboune; Mbainguinam, Dionadji; Fotclossou, Tara

    2016-01-01

    Introduction Le diabète sucré constitue un véritable problème de santé et ses complications touchent plusieurs organes dont les reins. Un diagnostic précoce de la néphropathie diabétique permet de prendre en charge les patients plus efficacement et de façon multidisciplinaire, de retarder sa progression vers l'insuffisance rénale chronique. Peu d'études ont été faites en Afrique dans ce domaine. Au Tchad, nous ne disposons pas de données statistiques sur l'atteinte rénale liée au diabète. C'est pourquoi nous nous proposons d'étudier la néphropathie diabétique avec pour objectifs d'analyser le profil de la néphropathie diabétique des patients de l'hôpital général de référence nationale de N'Djamena. Méthodes Nous avions mené une étude transversale descriptive à l'Hôpital Générale de Référence Nationale de N'Djamena d'avril à septembre 2012. Etaient inclus dans l'étude tous les patients diabétiques hospitalisés ou suivis dans les services de néphrologie et d'endocrinologie. Résultats Il y avait 54 cas de néphropathie diabétique sur 181 patients soit 29,80%. L'âge de plus de 50 ans représentait 87%, le sexe masculin dominait avec 67%, la durée d'évolution du diabète au moment de la découverte de la néphropathie était de 10,25 ans, la pression artérielle moyenne était de 138 mm Hg, l'HbA1C était supérieur à 6,5% dans 74,5%, l'insuffisance rénale terminale était retrouvée dans 26,90%, une protéinurie à 2,65 g/24 h était détectée dans 60,30%. 57,4% des patients avaient une rétinopathie diabétique au stade III. Conclusion Au Tchad, la fréquence de la néphropathie diabétique est de l'ordre de 29,83%. C'est une affection qui touche les hommes avec une moyenne d'âge de 58,7 ans. Le diabète de type 2 est le plus fréquent avec 90,7% des cas. Les facteurs de risque mal contrôlés pouvaient conduire la néphropathie diabétique vers une altération de la fonction rénale notamment l'HTA (70,8%), un d

  10. Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction test.

    PubMed

    Rouet, François; Chaix, Marie-Laure; Nerrienet, Eric; Ngo-Giang-Huong, Nicole; Plantier, Jean-Christophe; Burgard, Marianne; Peeters, Martine; Damond, Florence; Ekouevi, Didier Koumavi; Msellati, Philippe; Ferradini, Laurent; Rukobo, Sandra; Maréchal, Valérie; Schvachsa, Nilda; Wakrim, Lahcen; Rafalimanana, Christian; Rakotoambinina, Benjamin; Viard, Jean-Paul; Seigneurin, Jean-Marie; Rouzioux, Christine

    2007-08-01

    The high genetic diversity of HIV-1 has a major impact on the quantification of plasma HIV-1 RNA, representing an increasingly difficult challenge. A total of 898 plasma specimens positive for HIV-1 RNA by commercial assays (Amplicor v1.5; Roche Diagnostic Systems, Alameda, CA or Versant v3.0; Bayer Diagnostics, Emeryville, CA) were tested using the Agence Nationale de Recherches sur le SIDA second-generation (G2) real-time reverse transcriptase polymerase chain reaction (RT-PCR) test: 518 samples containing HIV-1 of known subtype, including 88 from 2 subtype panels and 430 harboring B (n = 266) and non-B (n = 164) group M HIV-1 subtypes from patients followed up in 2002 through 2005 at Necker Hospital (Paris, France), and 380 samples from 10 different countries (Argentina, Cambodia, Cameroon, Central African Republic, France, Ivory Coast, Madagascar, Morocco, Thailand, and Zimbabwe). HIV-1 RNA values obtained by G2 real-time PCR were highly correlated with those obtained by the Amplicor v1.5 for B and non-B subtypes (R = 0.892 and 0.892, respectively) and for samples from diverse countries (R = 0.867 and 0.893 for real-time PCR vs. Amplicor v1.5 and real-time PCR vs. Versant v3.0, respectively). Approximately 30% of specimens harboring non-B subtypes were underquantified by at least -0.51 log10 in Amplicor v1.5 versus 5% underquantified in G2 real-time PCR. Discrepant results were also obtained with subtype B samples (14% underquantified by Amplicor v1.5 vs. 7% by G2 real-time PCR). Similar percentages were observed when comparing results obtained with the G2 real-time PCR assay with those obtained using the Versant assay. Addressing HIV-1 diversity, continual monitoring of HIV-1 RNA assays, together with molecular epidemiology studies, is required to improve the accuracy of all HIV RNA assays.

  11. Note des Éditeurs scientifiques

    NASA Astrophysics Data System (ADS)

    Averbuch, P.

    Cette série d'articles est une revue de résultats expérimentaux sur différents "fluides" moléculaires, dans lesquels la cohésion est due à des forces de Van der Waals et à des liaisons hydrogène, l'eau étant un de ces fluides. Ces résultats sont présentés de façon à justifier expérimentalement un modèle original, non extensif, des propriétés de ces fluides, et l'ensemble se présente sous la forme de trois articles décrivant le modèle, suivis chacun par un article le comparant aux résultats expérimentaux publiés par de nombreux auteurs. Le caractère non extensif des propriétés physiques des fluides est choquant, contraire à beaucoup d'idées établies, il semble n'avoir en sa faveur qu'un argument, la comparaison avec un nombre de résultats expérimentaux assez grand pour que l'effet du hasard soit difficilement soupçonnable. En particulier, les écarts entre des résultats de mesures faits par des auteurs différents dans des conditions différentes sont expliqués, le sérieux et la compétence des différents expérimentateurs ne sont plus mis en doute : mais l'interprétation de ces résultats avec un modèle extensif non adapté est seule mise en cause. Les modèles extensifs étant utilisés systématiquement, au delà des expériences de physiciens, dans les calculs d'ingénieurs, et dans la modélisation d'appareils qui fonctionnent et de phénomènes naturels observés par tout le monde, il fallait expliquer pourquoi on pouvait renoncer à l'extensivité. Les raisons du succès pratique des modèles extensifs sont données, d'abord dans le cas des nématiques, puis dans celui des liquides ordinaires, et c'est ce qui rend l'ensemble cohérent, tant avec les mesures physiques fines qu'avec les observations quotidiennes. Il n'en reste pas moins que si l'interprétation donnée dans cette série d'articles est généralisable, une justification théorique du modèle utilisé devient nécessaire. Pour ce qui est des propriétés d'équilibre, une séparation de l'énergie libre en énergie libre de volume et en énergie libre de surface devrait donner les mêmes résultats ; par contre les choses deviennent troublantes dès que l'on passe aux coefficients de transport, c'est-à-dire à l'aspect macroscopique de la dynamique moléculaire. Il y a là un écart notable avec les conceptions courantes, ce qui rend très surprenante la lecture de ces articles. On peut mentionner la liste des problèmes théoriques posés par la description phénoménologique qui est celle de cette série d'articles : la généralisation de lois d'échelle en dehors de zones critiques n'est pas absolument nouvelle, par contre la simplicité des lois reliant l'exposant v à la température pose problème ; le sens des temps de relaxation utilisés est sans doute également à préciser. Enfin les modes considérés semblent n'intervenir dans les propriétés thermodynamiques que par un facteur par mode, comme si seulement l'énergie potentielle devait intervenir, les termes cinétiques ne participant pas vraiment aux transitions de phase. Tout cela pose donc problème, et l'on peut se demander si un pareil modèle peut être compatible avec tout ce qui est connu par ailleurs en physique statistique. Mais s'il rend bien compte de beaucoup de résultats expérimentaux, ce sont ces derniers qui seraient en difficulté avec la mécanique statistique. Il a donc semblé préférable de publier le modèle, sa justification expérimentale et de poser quelques problèmes, tant aux théoriciens, qui pourraient expliquer pourquoi un tel modèle rend compte de résultats observés, qu'aux expérimentateurs, qui pourraient reprendre certaines mesures, et délimiter le caractère plus ou moins général du modèle.

  12. NATO granulite conference

    NASA Astrophysics Data System (ADS)

    Vielzeuf, D.; Vidal, Ph.

    On September 5-9, 1988, 83 participants from 20 different countries gathered in Clermont- Ferrand, France, for the workshop Petrology and Geochemistry of Granulites a nd Related Rocks. All geoscience disciplines were represented. The workshop was cosponsored by Universite Blaise Pascal, UFR Scientifique et Technique, Centre National de la Recherche Scientifique, International Lithosphere Program (working Group 2c), IGCP Project 235, Societe Francaise d e Mineralogie, Ministere de l'Education Nationale (DAGIC), Ministere des Affaires Etrangeres (DGSTD), Conseil Regional d Auvergne , Conseil General du Puy de Dome, Mairie de Clermont-Ferrand.

  13. Analyse de la prise en charge du nouveau-né dans le cadre de la stratégie nationale de subvention des accouchements et des soins obstétricaux et néonatals d'urgence au Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou (Burkina Faso)

    PubMed Central

    Ouédraogo, Solange Odile Yugbaré; Yougbaré, Nestor; Kouéta, Fla; Dao; Ouédraogo, Moussa; Lougué, Claudine; Ludovic, Kam; Traoré, Ramata Ouédraogo; Yé, Diarra

    2015-01-01

    Introduction Il s'agit d'analyser la prise en charge du nouveau-né dans le cadre de la stratégie na-tionale de subvention des accouchements et des soins obstétricaux et néonatals d'urgence mis en place par le gouvernement du Burkina Faso en 2006. Méthodes Nous avons menée une étude à visée descriptive et analytique comportant un volet ré-trospectif du 01 janvier 2006 au 31 décembre 2010 portant sur les paramètres épidémiologiques, cliniques des nouveau-nés hospitalisés et un volet prospectif du 3 octobre 2011 au 29 février 2012 par une entrevue des accompagnateurs des nouveau-nés et des prestataires des services de santé. Résultats Les hospitalisations ont augmenté de 43,65% entre 2006 à 2010 Le taux de mortalité néo-natale hospitalière qui était de 11,04% a connu une réduction moyenne annuelle de 3,95%. L'entrevue a porté sur 110 accompagnateurs et 76 prestataires. La majorité des prestataires (97,44%) et des ac-compagnateurs (88,18%) étaient informés de la stratégie mais n'avait pas une connaissance exacte de sa définition. Les prestataires (94,74%) ont signalé des ruptures de médicaments, consommables médicaux et des pannes d’ appareils de laboratoire et d'imagerie. Parmi les accompagnateurs (89%) disaient être satisfaits des services offerts et (72,89%) trouvaient les coûts abordables mais évoquaient les difficultés du transport. Conclusion: La subvention a amélioré la prise en charge du nou-veau-né mais son optimisation nécessiterait une meilleur information et implication de tous les acteurs. Conclusion La subvention a amélioré la prise en charge du nouveau-né mais son optimisation nécessiterait une meilleur information et implication de tous les acteurs. PMID:26161166

  14. Description du langage scientifique (Description of Scientific Language)

    ERIC Educational Resources Information Center

    Widdowson, H. G.

    1977-01-01

    A description of scientific language using three approaches: text, textualization, and discourse. Scientific discourse is analogous to universal deep structure; text, to surface variations in diverse languages; and textualization, to transformational processes. The relationship of the primary and secondary (scientific) cultures and their languages…

  15. A l'écoute de nos instituts scientifiques.

    NASA Astrophysics Data System (ADS)

    Henrard, J.; Arnould, M.; Demaret, J.; Noels, A.; Vercheval, J.; Crommelynck, D.; Melchior, P.

    The authors give some important events which occurred during the last academic year 1981-1982 in six scientific institutes in Belgium (Groupe de mécanique céleste, Département de Mathématique, Facultés Universitaires de Namur; Institut d'Astronomie, d'Astrophysique et de Géophysique, Université Libre de Bruxelles; Institut d'Astrophysique, Université de Liège; l'Institut d'Aéronomie Spatiale de Belgique; Institut Royal Météorologique de Belgique; Observatoire Royal de Belgique).

  16. Etude RICH Nursing. Plus de connaissances et de preuves scientifiques

    PubMed Central

    SCHUBERT, MARIA

    2009-01-01

    L’importance et la validité des résultats de l’étude RICH-Nursing* ont été récemment mises en cause par certains milieux, ce qui a provoqué certaines incertitudes chez les infirmières. Les auteurs reviennent sur l’impact actuel de cette étude et évoquent les perspectives d’avenir. PMID:25221376

  17. A Recommended Methodology for Quantifying NDE/NDI Based on Aircraft Engine Experience (Le Projet de Methodologie Pour l’Evaluation du Controle Non- Destructif Fonde sur l’Experience Acquise sur les moteurs d’Avions)

    DTIC Science & Technology

    1993-04-01

    Scientifiques Voir Blgique Minist~ re de la De6fense Nationale NOR VEGE Ottawa, Ontario KI A 0K2 Norwegian Defence Research Establishment DANEMARK Attn...r6vision des turbines, le developpement des procedts de contr6le/examen non destructif NDE/NDI, et I’application des methodes statistiques. Les mati ... res prtsentees s’appliquent aux adronefs, aux motoristes et aux organisations de maintenance civils et militaires. Les conferences examineront les

  18. Discours didactique scientifique et competence de communication (Didactic Scientific Discourse and Communicative Competence).

    ERIC Educational Resources Information Center

    Cabut, Helene; And Others

    The situation of foreign students arriving in Paris with no knowledge of French 3 months prior to their enrollment in science and engineering courses gave the impetus for the development of a set of exercises designed to train these students in the listening and writing skills they would need for their courses. Exercises were devised based on…

  19. Epistomologie et apprentissage du langage scientifique (Epistemology and the Learning of Scientific Language)

    ERIC Educational Resources Information Center

    Mariet, Francois

    1976-01-01

    Discusses the construction of the corpus of scientific French upon an epistemological base. Three topics are treated: the need for such a base because of the differences existing among scientific languages, the value of such an approach, and some suggestions on method. Pedagogical consequences are noted. (Text is in French.) (AMH)

  20. Le Francais des Professions Scientifiques et Techniques (French for the Scientific and Technical Professions).

    ERIC Educational Resources Information Center

    Muller, Brigitte

    Two sequential courses in scientific and technical French developed as a supplement to third- and fourth-year college French, in response to expressed student and industry demand, had as their objectives to develop a general familiarity with products of the large French industrial companies and their United States affiliates and to develop means…

  1. L'appropriation du domaine scientifique chez l'eleve togolais

    NASA Astrophysics Data System (ADS)

    Lalancette, Lucie

    1998-12-01

    Science and technology are essential to sustainable development. They must be endogenous in nature to reduce the dependency and vulnerability of developing countries. Hence we seek to determine how Togolese students appropriate the field of science. Science education should answer fundamental educational needs by aiming for autonomy and individualization, that is, the skills and attitudes necessary to the resolution of, problems (and thus necessary to creativity), the concept of which includes the production of new ideas and adaptation to change. This basic scientific culture allows citizens to understand socioeconomic and environmental imperatives related to science and technology. This study answers the following questions: (1) How is the appropriation of knowledge by Togolese students favored? (2) What are the representations acquired by Togolese students in the science classroom regarding key research concepts, namely education, culture, science, knowledge and development? The objective of this research is to partially describe the context of science learning in the first cycle of the Second Degree in Togo, a French-language developing country of Africa, and particularly to understand the influence of the sociocultural setting on pedagogy and development. We first present our conception of science teaching, followed by the construction of knowledge in context. This research permits clearer propositions in terms of plausible explanations for the observed relationships among the categories of data. Indeed, the framework of the transmission of knowledge considerably influences the appropriation of the field of science by Togolese students. Science is a mythical and mystical field, still perceived as the "white mans's thing", in spite of favorable attitudes developed by students concerning the application of science and technology in their environment. By way of the favored learning methods (which also represent those of the traditional environment) and curricula (which are exogenous in nature), students formally appropriate scientific knowledge without actually transferring that knowledge outside the school setting. For this study, the validity of the propositions is dependent upon the perceptions of the key research concepts by the subjects. That is why the propositions are supported by the analysis of the Togolese student's answers during interviews, as well as by lectures given by African essayists. This is an a priori exploratory research, characterized by a qualitative methodology. The research concentrates on preliminary description and comprehension. Specifically, the method is based on an interpretive approach, while also being reflexive in nature. Observation data were gathered through documentation, field observations, a group discussion and a questionnaire. The pertinence of this study's results lies in a better understanding of the construction of knowledge in context.

  2. L'Harmonisation des langues maliennes: entre l'Integration nationale et régionale

    NASA Astrophysics Data System (ADS)

    Ouane, Adama

    1991-03-01

    The standardization of Malian languages, which began in the period after independence, has been an educational reform guided more by linguists than by any institutional framework laid down by the political authorities of the country. This situation has permitted the technical application of a scientific strategy, but it has not led to widespread and general acceptance of the formulas which have been worked out. The consequent opposition between technical and political considerations, which have admittedly not always been in conflict, has been complicated by a set of additional factors which have made it difficult to reconcile internal (national) harmonization, dictated by local tendencies and balances between languages, and the need to respect the (regional) ecolinguistics of the country, whose linguistic and sociocultural divisions frequently extend well into other countries of the sub-region. This conflict is illustrated by the example of Malian languages with a wide regional distribution — Bamanan (Bambara) and Fulfulde (Fulani) — and by that of languages with a narrower distribution such as Bomu and Syenara-Mamara. The standardization of orthography and the creation of terminology in the MAPE (Mandingo-Peul) Project are the manifestation of a general acceptance of regionalism, while the choice of central, standard languages has often been made without regard for regional factors.

  3. Results of screening activities in salt states prior to the enactment of the Nationall Waste Policy Act

    SciTech Connect

    Carbiener, W.A.

    1983-01-01

    The identification of potential sites for a nuclear waste repository through screening procedures in the salt states is a well-established, deliberate process. This screening process has made it possible to carry out detailed studies of many of the most promising potential sites, and general studies of all the sites, in anticipation of the siting guidelines specified in the Nuclear Waste Policy Act. The screening work completed prior to the passage of the Act allowed the Secretary of Energy to identify seven salt sites as potentially acceptable under the provisions of Section 116(a) of the Act. These sites were formally identified by letters from Secretary Hodel to the states of Texas, Utah, Mississippi, and Louisiana on February 2, 1983. The potentially acceptable salt sites were in Deaf Smith and Swisher Counties in Texas; Davis and Lavender Canyons in the Gibson Dome location in Utah; Richton and Cypress Creek Domes in Mississippi; and Vacherie Dome in Louisiana. Further screening will include comparison of each potentially acceptable site against disqualification factors and selection of a preferred site in each of the three geohydrologic settings from those remaining, in accordance with the siting guidelines. These steps will be documented in statutory Environmental Assessments prepared for each site to be nominated for detailed characterization. 9 references.

  4. BOOK REVIEW: Astronomie von Olbers bis Schwarzschild. Nationale Entwicklungen und internationale Beziehungen im 19. Jahrhundert (Acta Historica Astronomiae Vol. 16)

    NASA Astrophysics Data System (ADS)

    Sterken, C.; Dick, W. R.; Hamel, J.

    2002-12-01

    The 14th volume of the Acta Historica Astronomiae is the Proceedings of a Colloquium International Relationships in Astronomy (in German) organised by the History of Astronomy Section of the Astronomische Gesellschaft held on September 18 in Lilienthal, Germany. The book contains 13 articles on astronomical topics covering the 19th and 20th centuries. The first paper is by Guenther Oestmann and deals with contemporary assessments of Johann Hieronymus Schroeter's (1745-1816) astronomical works and with later judgements of the scientific importance and significance of his observations as seen by astronomers and historians. This report is complemented by a second article on Schroeter's 25-ft reflector in Lilienthal near Bremen. To this end, author Felix Luehning has constructed a scale model of the telescope, and shows how the building of a model brings a deeper understanding of function and handling of this instrument. This brings us to a third paper on telescope building in Lilienthal: Hans-Joachim Leue describes the cooperation of Johann Hieronymus Schroeter and Johann Gottlieb Schrader in developing a white reflecting metal alloy for use as telescope mirror. The fourth article, by Klaus Schillinger, describes on the basis of archival documents the aquisition history of the Herschel telescopes, including telescope quality check, repair and building. Memorial sites referring to Wilhelm Olbers, Johann Hieronymus Schroeter, Friedrich Wilhelm Bessel and Carl Friedrich Gauss are described by Arno Langkavel in two walks outlined in the very last paper of this book. Peter Brosche, in the fifth paper, discusses the rediscovery of Ceres in December1801, a discovery that was the result of the combined efforts of a theoretician (Gauss) and an observer (Zach). Juergen Hamel's paper is based on previously unused archival sources and discusses the outstanding role played by H. C. Schumacher (1780-1850, editor of the Astronomische Nachrichten) in the communication between astronomers in his days, when his working place at Altona still belonged to the kingdom of Denmark. This paper is followed by a second one by the same author and deals with the correspondence of H. C. Schumacher and H C. Oersted (1777-1851) and shows how intense and diverse their cooperation was. In a subsequent paper, Wolfgang Kokott describes the role of the Astronomisches Jahrbuch (published from 1776 by the Royal Academy of Sciences at Berlin), a ranking international publication, with Bode's modest Berlin Observatory serving as a clearinghouse of information originating from virtually all European countries. "Karl Schwarzschild and the professionalisation of Astrophysics" is the title of Theodor Schmidt-Kaler's contribution and presents Schwarzschild's contributions to professionalization of astronomy: establishment of course lectures and a permanent astrophysical laboratory, a tight connection between teaching and research, stimulations and suggestions for astronomy at high school and for the formation of high school teachers, international organisation, and the planning of a southern observatory. Peter Habison describes the contribution of Leo de Ball (1853-1916, Director of the Kuffner Observatory in Vienna) to international astronomy. Internationalization in astronomy is also discussed in a following paper by Gudrun Wolfschmidt on the establishment of the Vereinigte Astronomische Gesellschaft, the international Astronomische Gesellschaft in 1863 and finally the International Astronomical Union in 1919. In the second but last paper of the book, Hilmar Duerbeck describes the history of the Chilean National Observatory, beginning with its origins out of Gilliss' US Naval Expedition to the Southern Hemisphere in 1849, over its directors Moesta, Vergara, Obrecht and Ristenpart, to the middle of the 20th century. The paper also includes the astronomical development at the Universidad Catolica and various international expeditions, which aimed at the observations of solar eclipses, the Venus transit of 1882, and the Mars opposition of 1907. An overview of the evolution and the actual state of the international observatories Cerro Tololo, La Silla and Paranal, as well as Las Campanas is also given.

  5. Economie et enseignement a Madagascar. (Economy and Education in Madagascar.) Financement des systemes educatifs: etudes de cas Nationales 8.

    ERIC Educational Resources Information Center

    Hugon, Philippe

    The purpose of this volume is to analyze the problems of school finance in Madagascar, including those that have arisen in the past decade and those anticipated in the present decade (through 1980). More generally, this book examines past and future connections between the economic and educational systems in Madagascar. The author examines the…

  6. The Impact of Changing International Relations on the Scientific and Technical Community (Incidence sur la Communaute Scientifique et Technique des Transformations en cours dans les Relations Internationales.

    DTIC Science & Technology

    1993-04-01

    and their families, they are not any longer willing business cycle, but a total restructuring of industry. Most of to pay the heavy taxes to finance ...and valid time 5. In a situation with general reduction in public appropri- schedule. ations. universities are not able to finance the 15 said -yes...1JACQ11E\\flN, A. et al. (1986), Competition Unitqd States, Stanford: Stanford University Press. europdenne et cooperation entre entreprises en 3 pIORE. M. J

  7. Interpretation d'une Controverse Scientifique: Strategies Argumentatives d'Adolescentes et d'Adolescents Quebecois (Interpretation of a Scientific Controversy: Argument Strategies of Adolescents and Quebecois Adolescents).

    ERIC Educational Resources Information Center

    Bader, Barbara

    2003-01-01

    Sketches out the argumentative strategies used by three 17-year-old boys to interpret the disagreement presented to them. Shows that they were inclined to adduce current ideas about science--framed according to a realist, empiricist epistemology--but that there are grounds for thinking that high school students would be capable of actualizing…

  8. La politique scientifique comme mise en espace-temps de la recherche= Science Policy as Placed in the Space-Time Relationship of Research.

    ERIC Educational Resources Information Center

    Turmel, Andre

    1986-01-01

    The language used by scientists to discuss their work and the social logic underlying scientific research is examined, and viewed from the perspective and as an extension of the space-time continuum that scientists study. (Author/MSE)

  9. Northern Scientific Training Program: Annual Report, 1999-2000 = Programme de formation scientifique dans le Nord: Rapport annuel, 1999-2000.

    ERIC Educational Resources Information Center

    Department of Indian Affairs and Northern Development, Ottawa (Ontario).

    The Northern Scientific Training Program (NSTP) is managed by the Department of Indian Affairs and Northern Development as part of its mandate to foster science and technology in the Canadian North. NSTP supports Canadian universities in providing training that gives advanced and graduate students the opportunity to gain professional experience in…

  10. Local network interconnection through a satellite point-to-multipoint link. Ph.D. Thesis - Ecole Nationale Superieure des Telecommunications, 6 Jul. 1985

    NASA Technical Reports Server (NTRS)

    Duarte, O. Muniz Bandeira

    1986-01-01

    Four architectures to implement a point to multipoint satellite link protocol for communication services offered by the Telecom 1 satellite network are presented. A safe communication service with error correction and flow control facilities is described. It is shown that a time transparent communication system combines simplicity and cost advantages.

  11. L'Harmonisation des langues Maliennes: Entre l'intregration nationale et regionale (The Harmonization of the Malian Languages: Between National and Regional Integration).

    ERIC Educational Resources Information Center

    Ouane, Adama

    1991-01-01

    Assesses efforts to standardize the Malian languages, including the standardization of orthography and the creation of terminology in the Mandingo-Peul Project. Points to conflicts between technical and political considerations, and between local tendencies and balances among languages and the need to respect the ecolinguistics of the country.…

  12. Support for a special symposium to highlight the research of early career women physical chemists at the 2011 fall ACS nationall meeting, Aug 28-Sept

    SciTech Connect

    Geraldine Richmond

    2012-12-19

    The symposium was well attended during the 4-day symposium. The invited speakers were primarily women in early career stage (~4-8 years) with a few senior women and men as invited speakers or session chairs. Included in each day was a Poster Session for graduate students and a lunch in which the turn out was strong and the posters presented encouraged much of dialogue with the invited speakers, guests and others attending the ACS meeting and wanted to discuss the student’s research and meet with the speakers. Most all speakers and participants were very positive about the sessions and expressed that the funding to cover some expenses made it possible for them to attend the conference and the poster session luncheon. There was a total of 51 presenters, below are the speakers and their abstracts, in order presented:

  13. Opportunities for Tomorrow: National Learning Needs Assessment Summary Report = Des Possibilities pour L'Avenir: Rapport Sommaire sur L'Evaluation Nationale des Besoins en Apprentisage.

    ERIC Educational Resources Information Center

    Communications, Energy & Paperworkers Union of Canada, Ottawa (Ontario).

    The Communications, Energy, and Paperworkers Union of Canada assessed literacy learning needs. In focus group discussions, members were asked their perception of such needs in the face of changes in the workplace and society; local union officers (LUOs) were asked how they saw the role of unions in supporting members' literacy learning; employers…

  14. The IC1396N proto-cluster at a scale of ~250 AU

    NASA Astrophysics Data System (ADS)

    Neri, R.; Fuente, A.; Ceccarelli, C.; Caselli, P.; Johnstone, D.; van Dishoeck, E. F.; Wyrowski, F.; Tafalla, M.; Lefloch, B.; Plume, R.

    2007-06-01

    Aims:We investigate the mm-morphology of IC 1396 N with unprecedented spatial resolution to analyze its dust and molecular gas properties, and draw comparisons with objects of similar mass. Methods: We have carried out sensitive observations in the most extended configurations of the IRAM Plateau de Bure interferometer, to map the thermal dust emission at 3.3 and 1.3 mm, and the emission from the J=13_k→ 12k hyperfine transitions of methyl cyanide (CH3CN). Results: We unveil the existence of a sub-cluster of hot cores in IC 1396 N, distributed in a direction perpendicular to the emanating outflow. The cores are embedded in a common envelope of extended and diffuse dust emission. We find striking differences in the dust properties of the cores (β≃ 0) and the surrounding envelope (β≃ 1), very likely testifying to differences in the formation and processing of dust material. The CH3CN emission peaks towards the most massive hot core and is marginally extended in the outflow direction. Based on observations obtained at the IRAM Plateau de Bure Interferometer (PdBI). IRAM is funded by the Centre Nationale de la Recherche Scientifique (France), the Max-Planck Gesellschaft (Germany), and the Instituto Geográfico Nacional (Spain).

  15. Invatamantul cu Predarea in Limbile Minoritatilor Nationale din Romania. In Anul Scolar 1992/1993 = The Education System in Romania: Tuition in the Languages of Ethnic Minorities. The School Year 1992/1993 = L'enseignement dispense dans les langues des minorites nationales de Roumanie. L'annee scolaire 1992/1993.

    ERIC Educational Resources Information Center

    Council for National Minorities, Bucharest (Romania).

    Documentation of the Romanian system of language instruction in ethnic minority languages is presented in Romanian, French, and English. It consists of: relevant provisions from the national constitution concerning the rights of ethnic minority members; organization and functioning of the educational system at the elementary, middle, and secondary…

  16. Adaptation of the Army Standard KN 01020 (aanpassing van de krijgsmachtnorm kn 01020)

    DTIC Science & Technology

    2005-01-01

    ect "Testmethoden De referenties naar andere nationale en milieuvriendelijke verfsystemen’. intemnationale normen zijn gecontroleerd e geactualiseerd...namen. - De referenties naar andere nationale en intemnationale normen zijn gecontroleerd en geactualiseerd. ONGERUBRICEERD ONGERUBRICEERD I TNO

  17. The International Development Research Centre: A Guide for the Canadian University Research Community = Le Centre de recherches pour le developpement international: guide a l'intention des scientifiques des universites Canadiennes.

    ERIC Educational Resources Information Center

    Tillman, George; Wasilewski, Ania, Ed.

    Written in both English and French this is a manual for the Canadian research community. It describes the International Development Research Centre (IDRC) and its operations. The main objective of the IDRC is to assist scientists in developing countries to identify and conduct research into long term practical solutions to development problems.…

  18. La corrosion des matériaux de conteneurs pour déchets HAVL crédibilité scientifique de la prévision à long terme

    NASA Astrophysics Data System (ADS)

    Gras, Jean-Marie

    2002-10-01

    Traditionally, the corrosion behaviour of container materials can be predicted by extrapolation from relatively short-term experiments. Approaches to life prediction are described for two kinds of materials: carbon steel (corrosion allowance material) which must resist general corrosion, and passive materials (corrosion-resistant materials) which may suffer localized corrosion phenomena (pitting and crevice corrosion). The current theoretical and empirical basis for extrapolating the behavior of these materials to long periods emphasizes the significant gaps in understanding. To improve the credibility of life prediction, and to prove the robustness of geological disposal systems, predictive models based on mechanistic understanding are needed. This work is probably more difficult for the corrosion-resistant materials than for corrosion-allowance materials. To cite this article: J.-M. Gras, C. R. Physique 3 (2002) 891-902.

  19. The International System of Units (SI) in Oceanography. Report of IAPSO Working Group on Symbols, Units and Nomenclature in Physical Oceanography (SUN). Unesco Technical Papers in Marine Science 45. IAPSO Publication Scientifique No. 32.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Div. of Marine Sciences.

    This report introduces oceanographers to the International System of Units (SI) in physical oceanography. The SI constitutes a universal language, designed to be understood by all scientists. It facilitates their mutual comprehension and exchange of views and results of their work. The first part of the report is devoted to physical quantities,…

  20. Conference Proceedings of International High Speed Networks for Scientific and Technical Information, Held at Ottawa, Canada on 6-7 October 1993 (Les Reseaux Internationaux Rapides D’Echange D’Information Scientifique et Technique)

    DTIC Science & Technology

    1994-02-01

    Unidad de In the information systems you can obtain the addresses Coordinaci6n de Bibliotecas (CBIC) of CSIC and the 0 of OPACs (Open Public Access... bibliotecas y unidades de informacion en ia empresa", Documentaci6n Cientifica, Jul-Sep 1992, ISSN 0210-0614. li-I TRAINING & OPERATIONS SUPPORT SYSTEM

  1. A Research Agenda for Scientific and Technical Information Held in Lisbon, Portugal on 7-9 April 1992 (Un Programme de Recherche pour l’Information Scientifique et Technique).

    DTIC Science & Technology

    1992-11-01

    field of inquiry. Good solid research advances fault library science and information science for not ask- the state of the art by contributing to the...further research and application. Ennis (1967) problems faced each day by practitioners. Robert Smith commented that library science research is...under ogy, and technical communications. Library science the title "On Information Science." Keren raises interest- and information science have been

  2. The Psychology of Violent Conflict in Failing States: A Review of the Scientific Literature (Psychologie des Conflits Violents au sein d’etats en Deroute: Analyse de Publications Scientifiques)

    DTIC Science & Technology

    2010-12-01

    Drazen, J. M., Bush, G. W., & Gore, A. (2000). The Republican and Democratic candidates speak on health care. New England Journal of Medicine , 343...American Psychologist, 56, 319–331. Smith, A. (1759/2000). The theory of moral sentiments. New York, NY: Prometheus Books. Smith, C. A., & Ellsworth

  3. Switch to Rilpivirine/Emtricitabine/Tenofovir Single-Tablet Regimen of Human Immunodeficiency Virus-1 RNA-Suppressed Patients, Agence Nationale de Recherches sur le SIDA et les Hépatites Virales CO3 Aquitaine Cohort, 2012–2014

    PubMed Central

    Cazanave, Charles; Reigadas, Sandrine; Mazubert, Cyril; Bellecave, Pantxika; Hessamfar, Mojgan; Le Marec, Fabien; Lazaro, Estibaliz; Peytavin, Gilles; Bruyand, Mathias; Fleury, Hervé; Dabis, François; Neau, Didier

    2015-01-01

    Background. The purpose of this study was to assess the efficacy and tolerability of combined antiretroviral therapy (cART) in human immunodeficiency virus (HIV)-1 virologically suppressed patients who switched to rilpivirine (RPV)/tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) as a single-tablet regimen (STR). Methods. A retrospective multicenter cohort study was performed between September 2012 and February 2014 in Bordeaux University Hospital-affiliated clinics. Patients with a plasma HIV viral load (VL) lower than 50 copies/mL and switching to STR were evaluated at baseline, 3, 6, 9, and 12 months from switch time (M3, M6, M9, M12) for VL and other biological parameters. Change from baseline in CD4 cell counts was evaluated at M6 and M12. Virological failure (VF) was defined as 2 consecutive VL >50 copies/mL. Results. Three hundred four patients were included in the analysis. Single-tablet regimen switch was proposed to 116 patients with adverse events, mostly efavirenz (EFV)-based (n = 59), and to 224 patients for cART simplification. Thirty of 196 patients with available genotype resistance test results displayed virus with ≥1 drug resistance mutation on reverse-transcriptase gene. After 12 months of follow-up, 93.4% (95.5% confidence interval, 89.9–96.2) of patients remained virologically suppressed. There was no significant change in CD4 cell count. During the study period, 5 patients experienced VF, one of them harboring RPV resistance mutation. Clinical cART tolerability improved in 79 patients overall (29.9%) at M6, especially neurological symptoms related to EFV. Fasting serum lipid profiles improved, but a significant estimated glomerular function rate decrease (−11 mL/min/1.73 m2; P < 10−4) was observed. Conclusions. Overall, virologic suppression was maintained in patients after switching to RPV/TDF/ FTC. This STR strategy was associated with improved tolerability. PMID:26034768

  4. Marker segregation information in breast/ovarian cancer genetic counseling: is it still useful? Groupe Génétique et Cancer de la Fédération Nationale des Centres de Lutte Contre le Cancer.

    PubMed

    Essioux, L; Girodet, C; Sinilnikova, O; Pagès, S; Eisinger, F; de Résende, S; Maugard, C; Lanoë, D; Longy, M; Bignon, Y J; Sobol, H; Bonaïti-Pellié, C; Stoppa-Lyonnet, D

    1998-09-23

    The use of mutation screening of BRCA1 and BRCA2 genes as a genetic test is still to a certain extent limited and the oncogeneticist may want to use complementary approaches to identify at-risk individuals. In a series of 23 families with at least three breast or ovarian cancer cases, screened for mutations at BRCA1 and BRCA2 and typed for markers at both loci, we investigated the usefulness of marker segregation information at two levels: 1) to what extent can the indirect approach identify the mutation carrier status of screened cases and their first-degree relatives, and 2) in what way does it help to identify the gene implicated in a family in which neither BRCA1 nor BRCA2 mutation has been detected? Using the indirect approach, the carrier status of the screened case could be determined with quasi certainty in three families and with a high probability in eight families. This status could be inferred in unaffected first-degree relatives as almost certain in one family and as highly probable in six families. Fourteen mutations were found concurrently in our series. Among the nine mutation-negative families, we were able to conclude that a BRCA1 mutation most probably segregated in one and that a mutation other than BRCA1 and BRCA2 was probably involved in two families. Our results show that, in small families, little help is to be expected from linkage data and mutation screening is the only way of identifying the origin of a genetic predisposition in a family. Marker segregation information may be useful in some large breast/ovarian cancer families in which no BRCA1 or BRCA2 mutation has been detected.

  5. Biosimilars: from technical to pharmacoeconomic considerations. 30th Rencontres Nationales de Pharmacologie et Recherche clinique pour l'Innovation et l'Evaluation des Technologies de Santé. Tables rondes.

    PubMed

    Girault, Danièle; Trouvin, Jean-Hugues; Blachier-Poisson, Corinne; Gary, François; Laloye, Didier; Bergmann, Jean-François; Casadevall, Nicole; Delval, Cécile; De Sahb Berkovitch, Rima; Fagon, Jean-Yves; Gersberg, Marta; Lassale, Catherine; Lechat, Philippe; Le Jeunne, Claire; Montastruc, Jean-Louis; Prugnaud, Jean-Louis; Ratignier-Carbonneil, Christelle; Rey-Coquais, Cécile

    2015-01-01

    A biosimilar is a biological medicinal product claimed to be similar to a reference biological medicinal product. Its development plan includes studies comparing it with the reference product in order to confirm its similarity in terms of quality, preclinical safety, clinical efficacy, and clinical safety, including immunogenicity. Biosimilars differ from generics both in their molecular complexity and in the specific requirements that apply to them. Since patents on many biological medicinal products will expire within the next 5 years in major therapeutic areas such as oncology, rheumatology and gastroenterology and as those products are so costly to the French national health insurance system, the availability of biosimilars would have a considerable economic impact. The round table has issued a number of recommendations intended to ensure that the upcoming arrival of biosimilars on the market is a success, in which prescribing physicians would have a central role in informing and reassuring patients, an efficient monitoring of the patients treated with biologicals would be set up and time to market for biosimilars would be speeded up.

  6. Recherche universitaire et priorites nationales: l'effet du financement public sur la recherche energie solaire au Canada (University Research and National Priorities: The Effect of Public Financing on Solar Energy Research in Canada).

    ERIC Educational Resources Information Center

    Dalpe, Robert; Gingras, Yves

    1990-01-01

    The role of two main sources of university research financing in solar energy is examined to assess whether they oriented research in the direction of government programs. The strongest relationship appears to be in journal publication patterns. This scientific community has acquired the capacity to tap varying sources. (Author/MSE)

  7. Switch to Rilpivirine/Emtricitabine/Tenofovir Single-Tablet Regimen of Human Immunodeficiency Virus-1 RNA-Suppressed Patients, Agence Nationale de Recherches sur le SIDA et les Hépatites Virales CO3 Aquitaine Cohort, 2012-2014.

    PubMed

    Cazanave, Charles; Reigadas, Sandrine; Mazubert, Cyril; Bellecave, Pantxika; Hessamfar, Mojgan; Le Marec, Fabien; Lazaro, Estibaliz; Peytavin, Gilles; Bruyand, Mathias; Fleury, Hervé; Dabis, François; Neau, Didier

    2015-01-01

    Background.  The purpose of this study was to assess the efficacy and tolerability of combined antiretroviral therapy (cART) in human immunodeficiency virus (HIV)-1 virologically suppressed patients who switched to rilpivirine (RPV)/tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) as a single-tablet regimen (STR). Methods.  A retrospective multicenter cohort study was performed between September 2012 and February 2014 in Bordeaux University Hospital-affiliated clinics. Patients with a plasma HIV viral load (VL) lower than 50 copies/mL and switching to STR were evaluated at baseline, 3, 6, 9, and 12 months from switch time (M3, M6, M9, M12) for VL and other biological parameters. Change from baseline in CD4 cell counts was evaluated at M6 and M12. Virological failure (VF) was defined as 2 consecutive VL >50 copies/mL. Results.  Three hundred four patients were included in the analysis. Single-tablet regimen switch was proposed to 116 patients with adverse events, mostly efavirenz (EFV)-based (n = 59), and to 224 patients for cART simplification. Thirty of 196 patients with available genotype resistance test results displayed virus with ≥1 drug resistance mutation on reverse-transcriptase gene. After 12 months of follow-up, 93.4% (95.5% confidence interval, 89.9-96.2) of patients remained virologically suppressed. There was no significant change in CD4 cell count. During the study period, 5 patients experienced VF, one of them harboring RPV resistance mutation. Clinical cART tolerability improved in 79 patients overall (29.9%) at M6, especially neurological symptoms related to EFV. Fasting serum lipid profiles improved, but a significant estimated glomerular function rate decrease (-11 mL/min/1.73 m(2); P < 10(-4)) was observed. Conclusions.  Overall, virologic suppression was maintained in patients after switching to RPV/TDF/ FTC. This STR strategy was associated with improved tolerability.

  8. Collaborateurs aux lignes directrices en soins primaires

    PubMed Central

    Allan, G. Michael; Kraut, Roni; Crawshay, Aven; Korownyk, Christina; Vandermeer, Ben; Kolber, Michael R.

    2015-01-01

    Résumé Objectif Déterminer la profession des collaborateurs scientifiques aux lignes directrices, les variables associées aux différences de participation des collaborateurs et si oui ou non les lignes directrices en soins primaires fournissent un énoncé sur les conflits d’intérêts. Type d’étude Analyse rétrospective des lignes directrices en soins primaires affichées sur le site web de l’Association médicale canadienne. Deux extracteurs de données indépendants ont examiné les lignes directrices et ont extrait les données pertinentes. Contexte Canada Principaux paramètres à l’étude Commanditaires des lignes directrices, territoire (national ou provincial) visé par les lignes directrices, profession des collaborateurs scientifiques aux lignes directrices et énoncés de conflits d’intérêts rapportés dans les lignes directrices. Résultats Sur les 296 lignes directrices de pratique clinique trouvées dans la section de la médecine familiale de l’Infobanque AMC, 65 apparaissaient en double et 35 se rapportaient de façon limitée à la médecine familiale. Vingt ne fournissaient aucune information sur les collaborateurs scientifiques, ce qui laissait 176 lignes directrices propices à l’analyse. Au total, il y avait 2495 collaborateurs (auteurs et membres de comité) : 1343 (53,8 %) spécialistes autres que des médecins de famille, 423 (17,0 %) médecins de famille, 141 (5,7 %) infirmières, 75 (3,0 %) pharmaciens, 269 (10,8 %) autres cliniciens, 203 (8,1 %) scientifiques non cliniciens et 41 (1,6 %) collaborateurs de profession inconnue. La proportion des collaborateurs de ces professions différait significativement entre les lignes directrices nationales et provinciales, de même qu’entre les lignes directrices financées par l’industrie et celles qui ne l’étaient pas (p < 0,001 dans les 2 cas). Dans le cas des lignes directrices de pratique clinique provinciales, 30,8 % des collaborateurs étaient des médecins de

  9. Préface

    NASA Astrophysics Data System (ADS)

    Aspect, Alain

    2004-11-01

    COLOQ est une conférence regroupant, tous les deux ans, la communauté scientifique et industrielle nationale travaillant dans les domaines des lasers, de l'optique non-linéaire et de l'optique quantique. Elle s'est tenue pour sa huitième édition à Toulouse, du 3 au 5 septembre 2004, sur le campus de I'INSA. Comme il est de tradition tous les quatre ans, COLOQ était couplé avec Horizons de l'optique, avec en particulier une journée commune dont le programme avait été préparé en concertation par les deux comités scientifiques. Depuis sa création, COLOQ a pour but de favoriser les rencontres entre les chercheurs des différents laboratoires nationaux publics ou privés travaillant sur les lasers et l'optique quantique au sens large. C'est un moyen privilégié de resserrer les liens de cette communauté et d'y intégrer les jeunes chercheurs. Ces derniers y trouvent l'occasion de se connaître, de se faire connaître, de découvrir la communauté à laquelle ils appartiennent et d'élargir leurs connaissances des thèmes qui la structurent. La participation de 230 chercheurs et d'une vingtaine d'exposants de matériels spécialisés dans les lasers et l'optoélectronique témoigne de la vitalité de COLOQ et de son audience dans les laboratoires et chez les industriels de l'optique. Le programme de COLOQ 8 comportait d'une vingtaine de conférences générales données par des chercheurs de renom international, et des séances de communications par affiches, occasions privilégiées de rencontres et d'échanges. Les exposés ont porté sur des sujets particulièrement actifs au niveau national et international, avec un accent sur des thèmes importants pour la région toulousaine : contrôle cohérent, optique et nanosciences, optique et astronomie, sans oublier la traditionnelle rubrique phénomènes fondamentaux, éclectique pour ne pas dire hétéroclite, mais si représentative d'une des ambitions de COLOQ qui est d'offrir à ses participants une

  10. The impact of qualitative research on gynaecologic oncology guidelines.

    PubMed

    How, Jeffrey Andrew; Abitbol, Jeremie; Lau, Susie; Gotlieb, Walter Henri; Abenhaim, Haim Arie

    2015-02-01

    Objectif : Les soins offerts aux patientes atteintes d’un cancer comptent une importante composante psychosociale, laquelle a été explorée de façon scientifique par l’intermédiaire de la recherche qualitative. Notre étude avait pour objectif d’évaluer la disponibilité de la recherche qualitative en gynéco-oncologie et d’en mesurer l’intégration aux directives cliniques relevant du domaine de la gynéco-oncologie. Méthodes : Nous avons mené des recherches dans diverses bases de données (Medline, CINHAL, Scopus et Web of Science) en vue de cerner la disponibilité de la recherche qualitative menée au cours des 20 dernières années au sujet des trois cancers gynécologiques les plus prévalents : les cancers de l’endomètre, de l’ovaire et du col utérin. Des directives cliniques nationales et internationales portant sur la prise en charge des cancers gynécologiques ont été sélectionnées au moyen du site Web National Guideline Clearinghouse, du site Web de la Société des obstétriciens et gynécologues du Canada, et du répertoire Standards and Guidelines Evidence de lignes directrices sur le cancer. Une analyse bibliométrique a été utilisée pour déterminer la fréquence des références qualitatives citées dans les directives cliniques en question. Résultats : Nous avons identifié 113 mémoires de recherche qualitative portant sur des cancers gynécologiques qui se centraient sur les effets psychologiques, sur la dynamique sociale et sur les interactions médecin-patiente dans le cadre du traitement anticancéreux et de la récupération. Au sein des 15 directives cliniques nationales et internationales portant sur la prise en charge des cancers gynécologiques que nous avons identifiées, nous avons dénombré un total de 2 272 références; parmi ces dernières, seules trois références citant une recherche qualitative ont été identifiées (0,1 %), et ce, au sein d’une seule directive clinique parmi les 15

  11. Préface

    NASA Astrophysics Data System (ADS)

    Chardonnet, Christian; Millot, Guy

    2006-10-01

    COLOQ, réunion nationale biennale initiée en 1988 par la communauté française des lasers, de l'optique non linéaire et de l'optique quantique atteint sa neuvième édition. Depuis sa création, les objectifs poursuivis sont les suivants : - réunir la communauté française des lasers, de l'optique non linéaire et de l'optique quantique, en dépassant les clivages fondamental/appliqué, recherche publique/industrielle, - faire le point sur les avancées récentes, - permettre aux jeunes chercheurs de se rencontrer, de s'exprimer et de s'aguerrir au plan national. Le but est que tout thésard du domaine de l'optique puisse participer à COLOQ une fois durant sa thèse, présenter son travail et de se confronter à la communauté de l'optique. COLOQ9 s'est tenu, pour sa 9e édition, sur le campus universitaire de Dijon, du 7 au 9 septembre 2005. Il a été une grande réussite : nombre de participants (255) et de présentations scientifiques record (148 affiches), forte représentation des industriels (15) et participation d'environ 200 lycéens aux conférences grand public. Le nombre plus élevé que prévu d'affiches a rendu un peu serrée leur présentation : une attention particulière sera portée à cet aspect lors des prochaines éditions. Ces journées ont été consacrées à des conférences invitées données par des scientifiques de haut niveau et à des présentations sous forme d'affiches. Une plage de temps importante a été réservée pour des discussions autour des affiches. À proximité immédiate de la salle de conférence, l'exposition de matériels spécialisés pour les lasers, l'optique et l'optoélectronique a été une occasion pour les jeunes participants de découvrir et contacter les industriels et les autres grands acteurs de l'optique. L'année 2005 ayant été l'année mondiale de la physique, COLOQ9 a retenu comme thème central ”1905-2005 : à propos d'Einstein". Plusieurs grandes conférences ont été dédiées à ce th

  12. Examination of Rotating Spoke Instability in a Cross-Field Discharge

    DTIC Science & Technology

    2013-07-08

    Vaudolon ** R. Schneider, K. Matyash *** Y. Raitses, A. Diallo, Y. Shi * CTRE Nat De La Recherche Scientifique , CNRS MOY800 CTRE Poitou...Charente, 3, Ave Recherche Scientifique , Orleans 45000 France ** Ernst-Moritz-Arndt Universitat Greifswald, Greifswald, Germany *** Princeton Plasmas...7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) * CTRE Nat De La Recherche Scientifique , CNRS MOY800 CTRE Poitou Charente, 3, Avenue

  13. Does research through Structured Operational Research and Training (SORT IT) courses impact policy and practice?

    PubMed

    Kumar, A M V; Shewade, H D; Tripathy, J P; Guillerm, N; Tayler-Smith, K; Berger, S Dar; Bissell, K; Reid, A J; Zachariah, R; Harries, A D

    2016-03-21

    Contexte : Les cours de l'Initiative de Recherche et de Formation Structurées Opérationnelles (SORT IT) sont bien connus pour leurs bons résultats : près de 90% des participants terminent le cours et publient dans des revues scientifiques.Objectif : Evaluer l'impact sur la politique/les pratiques de ces articles de recherche qui ont été le résultat de six cours SORT IT initiés entre juillet 2012 et mars 2013.Schéma : Une étude transversale impliquant des questionnaires auto-administrés envoyés par courriel et des réponses par téléphone/skype/en personne des auteurs principaux et/ou des co-auteurs des articles liés au cours. Une analyse descriptive du contenu des réponses a été réalisée et catégorisée par thèmes.Résultats : Sur 72 participants, 63 (88%) ont terminé le cours. Les résultats du cours ont inclus 81 articles soumis, dont 76 (94%) ont été publiés. Sur les 81 articles publiés évalués, 45 (55%) ont contribué à une modification de la politique et/ou des pratiques : 29 articles ont contribué à une modification de la politique/des pratiques par le gouvernement (20 au niveau national, 4 au niveau sous-national et 5 au niveau hospitalier), 11 à des modifications de politique d'organisations non gouvernementales et cinq à un renforcement de la politique existante. Ces changements allaient de modifications des outils de suivi et d'évaluation à une nouvelle rédaction des directives nationales et à une accélération des politiques existantes.Conclusion : Plus de la moitié des articles du cours SORT IT ont contribué à une modification de la politique et/ou des pratiques. Les évaluations futures devraient inclure des vérifications plus solides et indépendantes des modifications rapportées avec toutes les parties concernées afin d'améliorer leur rigueur et leur richesse.

  14. Collaborative Medical Reasoning in Telemedicine

    DTIC Science & Technology

    2007-11-02

    Nationale Supérieure des Télécommunications de Bretagne , Brest, France. 2Centro de Procesamiento de Imagenes, Universidad de Carabobo, Valencia...Performing Organization Name(s) and Address(es) Ecole Nationale Supérieure des Télécommunications de Bretagne , Brest, France. Performing Organization Report

  15. Synchrotron Radiation Based Study of X-Ray Absorption of Flame Generated Nanoparticles

    DTIC Science & Technology

    2007-11-02

    induced ionization of nanoparticles, a proposal was prepared for submission to the French Government sponsored Programme Nationale du Physico- Chimie du...by the European Synchrotron Radiation Facility and by the French Programme Nationale du Physico- Chimie du Milieu Interstellaire. Special thanks are due

  16. Cumulative Viral Load and Virologic Decay Patterns After Antiretroviral Therapy in HIV-Infected Subjects Influence CD4 Recovery and AIDS

    DTIC Science & Technology

    2011-05-20

    Cohorte Agence Nationale de Recherches sur le SIDA EP 11 study. J Infect Dis 186: 710–714. 8. Hermankova M, Ray SC, Ruff C, Powell-Davis M, Ingersoll R, et...malignancy in HIV-infected patients during the combination antiretroviral therapy era: Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine

  17. Multiscale Problems in Materials Science: A Mathematical Approach to the Role of Uncertainty

    DTIC Science & Technology

    2010-10-01

    Claude Lebris Ecole Nationale des Ponts et Chaussées CERMICS 6-8, Avenue Blaise Pascal Marne la Vallée, France FR-77455 EOARD SPC 10-4002...Ecole Nationale des Ponts et Chaussées 6-8, Avenue Blaise Pascal Marne la Vallée FR-77455 France 8. PERFORMING ORGANIZATION REPORT NUMBER

  18. Preface

    NASA Astrophysics Data System (ADS)

    Aspect, Alain

    2002-06-01

    COLOQ est une conférence regroupant, tous les deux ans, la communauté scientifique et industrielle nationale travaillant dans les domaines des lasers, de l'optique non-linéaire et de l'optique quantique. Elle s'est tenue pour sa septième édition à Rennes, du 5 au 7 septembre 2001, sur le campus de Beaulieu de l'Université de Rennes I. Cette réunion a pour but de favoriser les rencontres entre les membres des différents laboratoires nationaux publics ou privés travaillant sur ces sujets. C'est donc un moyen privilégié de resserrer les liens de cette communauté et d'y intégrer les jeunes chercheurs. Une dimension importante de COLOQ est de permettre aux jeunes chercheurs de se connaître, de se faire connaître, de découvrir la communauté à laquelle ils appartiennent et d'élargir leurs connaissances des thèmes qui la structurent. La participation de 200 chercheurs et de 18 exposants de matériels spécialisés dans les lasers et l'optoélectronique témoigne de la vitalité de COLOQ. Le programme de COLOQ 7 a comporté des conférences générales données par des chercheurs de renom international et des séances de communications par voie d'affiches. Les exposés ont porté sur des sujets d'optique particulièrement actifs au niveau national et international : les télécoms, thème cher à la région Bretagne en particulier, les phénomènes fondamentaux, les nouvelles percées de l'optique en métrologie et mesures ultra-sensibles, sujets privilégiés du laboratoire organisateur, les sources de l'extrême (incluant X et V-UV). Parallèlement à 20 conférences invitées, 130 communications par affiches ont présenté, tout au long du colloque, les plus récents résultats concernant les atomes froids et la métrologie, les télécoms optiques, l'optique non-linéaire et les nouveaux matériaux, les nanostructures et l'optique de champ proche, la physique des lasers, etc. Ce volume spécial du Journal de Physique IV regroupe la presque totalit

  19. Line Intensities and Self-Broadening Coefficients of 12 Carbon 16 Oxygen(2) and 13 Carbon 16 Oxygen(2) Lines in the Laser Band Region

    DTIC Science & Technology

    1992-03-25

    National de la Recherche Scientifique , Universitd Pierre et Marie Curie, Tour 13, Bte 76, 4, Place Jussieu, 75252 PARIS CEDEX 05, France 0 92-090634 08... Scientifique , Universit6 Pierre et Marie Curie, Tour 13, Bte 76, 4, Place Jussieu, 75252 PARIS CEDEX 05, France -2- This report is divided into two parts

  20. Problem of Questioning

    SciTech Connect

    2005-10-31

    Le Prof.Leprince-Ringuet, chercheur sur le plan scientifique, artistique et humain, parle de la remise en question des hommes et la remise en question scientifique fondamentale ou exemplaire- plusieurs personnes prennent la parole p.ex Jeanmairet, Adam, Gregory. Le Prof.Gregory clot la soirée en remerciant le Prof.Leprince-Ringuet

  1. Problem of Questioning

    ScienceCinema

    None

    2016-07-12

    Le Prof.Leprince-Ringuet, chercheur sur le plan scientifique, artistique et humain, parle de la remise en question des hommes et la remise en question scientifique fondamentale ou exemplaire- plusieurs personnes prennent la parole p.ex Jeanmairet, Adam, Gregory. Le Prof.Gregory clot la soirée en remerciant le Prof.Leprince-Ringuet

  2. List of Standards to Accompany Manual of Documentation Practices Applicable to Defence-Aerospace Scientific and Technical Information (Liste des Normes a Placer en Annexe au Manuel Concernant les Techniques Documentaires Applicables a l’Information Scientifique et Technique de la Defense et du Secteur Aerospatial)

    DTIC Science & Technology

    1990-10-01

    1978 GENERAL METHODS FOR ANALYSING DOCUMENTS AND DETERMINING THEIR SUBJECTS Z 47-103 1O0 DOCUMENTATION - MONOLINGUAL AND MULTILINGUAL THESAURI...PARTICULARLY FOR USE IN CLASSFD DEFINING VOCABS ISO 2788 1986 DOCMENTN-GUIDELINES FOR ESTANMENT & DEVLPMENT UP MONOLINGUAL THESAURI ISO 3186 1988 CODES...DOCUMENTATION - GUIDELINES FOR THE ESTABMENT & DEVLPMENT OF MULTILINGUAL THESAURI IUO/R 0860 1968 INTERNATIONAL UNIFICATION OF CONCEPTS AND TERMS ISO/R 0919

  3. Communique: Special Issue on the International Scientific Conference and Exhibit and the 7th Session of the International Co-Ordinating Council for MAB (Paris, Sept. 22-Oct. 2, 1981) = Numero special sur la Conference Scientifique Internationale et Exposition et al 7e session du Counseil International de Coordination du MAB (Paris, du 22 Sept. au 2 Oct. 1981).

    ERIC Educational Resources Information Center

    Communique, 1982

    1982-01-01

    Presented are summaries of two separate but closely-related conferences. The International Scientific Conference and Exhibit, organized to mark the 10th anniversary of the Man and the Biosphere Program (MAB), was based on the theme "ecology in practice: establishing a scientific basis for land management." This summary includes: a 10…

  4. Communique: Special Issue on the International Network for Cooperation in Northern Science Created at a Meeting held in Edmonton, Alberta (October 12-15, 1982). Summary of Discussions and Agreements Reached = Numero special sur le Reseau Scientifique Internationale pour le Nord cree a la reunion tenue a Edmonton, Alberta (du 12 au 15 octobre 1982). Resume des discussions et accords conclus.

    ERIC Educational Resources Information Center

    Communique, 1983

    1983-01-01

    Delegations from Canada, Finland, Greenland, Norway, Sweden, and the United States agreed to the establishment of a network for cooperation among individuals engaged in problems peculiar to the circumpolar North. The Northern Science Network, established within the Unesco Man and the Biosphere Program, consists of three themes: studies on the…

  5. Optical Disk Technology and the Library. Part 1: The Technology and Its Applications. Part 2: The National Library Videodisc Demonstration Project. Canadian Network Papers Number 9 = Technologie du Videodisque et la Bibliotheque. Premiere partie: La Technologie et ses Applications. Deuxieme partie: Projet de Demonstration du Videodisque a la Bibliotheque Nationale. Documents sur les Reseaux Canadiens Numero 9.

    ERIC Educational Resources Information Center

    Duchesne, Roddy; Sonnemann, Sabine S.

    This report is intended to assist Canadian libraries in assessing potential library applications of optical disk technology. Part 1 provides a general outline of the technology and describes a number of library applications and projects. Descriptions are purposely general and illustrative in nature since the technology and its applications are…

  6. Digital Atlas and Evaluation of the Influence of Inter-Annual Variability on Climate Analyses

    DTIC Science & Technology

    2003-09-01

    Abstracts, Institute Nationale di Oceanografia e di Geofisica Sperimentale-OGS, Trieste, Italy 2001 р. 65 Unesco 1993: Manual of quality control procedures for validation of oceanographic data, IOC UNESCO, pp.436. 995

  7. Regelungen im Verkehr mit Lebensmitteln und Bedarfsgegenständen in Deutschland

    NASA Astrophysics Data System (ADS)

    Thomas, Gundula; Freund, Astrid; Gründig, Friedrich

    Im Zuge der Globalisierung von Produktion und Handel ändert sich auch der Charakter der Vorschriften im Lebensmittelrecht. Zunehmend treten internationale Rechtsbestimmungen, Abkommen, Standards und andere Normen an die Stelle nationaler Regelungen.

  8. Les bons conseils de la naissance à la maternelle

    PubMed Central

    Rourke, Leslie; Leduc, Denis; Constantin, Evelyn; Carsley, Sarah; Rourke, James; Li, Patricia

    2013-01-01

    Résumé Objectif Donner un aperçu de la version 2011 du Relevé postnatal Rourke (RPR), qui comporte aussi des nouveautés dans son site web et de nouvelles initiatives connexes et qui intègre les données des ouvrages scientifiques récents sur les soins de santé préventifs à l’intention des enfants de 0 à 5 ans. Qualité des données À l’instar des versions antérieures du RPR, la nouvelle édition présente des recommandations identifiées comme se fondant sur des preuves suffisantes, acceptables ou consensuelles, selon les classifications adoptées par le Groupe d’étude canadien sur les soins de santé préventifs en 2011. Message principal De nouveaux renseignements et des recommandations sont présentés concernant la surveillance de la croissance, la nutrition et la vaccination contre la varicelle, les pneumocoques, les méningocoques et le rotavirus. Il y a maintenant de bonnes données probantes en faveur de l’adaptation canadienne des courbes de croissance de l’Organisation mondiale de la Santé, du dépistage universel des problèmes d’audition chez le nouveau-né et du recours à des stratégies de réduction de la douleur liée à la vaccination. On a mis à jour les conseils anticipatoires concernant la sécurité durant le sommeil, la supervision de la santé des enfants en foyer d’accueil, le trouble du spectre de l’alcoolisation fœtale, les facteurs de risque nécessitant le dépistage du plomb et de l’anémie, les soins dentaires et la santé buccale. Parmi les nouvelles rubriques dans le site web du RPR, on peut mentionner une section présentant des ressources pour les parents, des modifications à l’intention de populations particulières, comme les personnes vivant au Nunavut, une version du RPR qui met en évidence en un coup d’œil les modifications à la version de 2009 et une expansion de la fonction d’exploration du RPR accompagnée des hyperliens connexes menant aux renseignements pertinents. On peut

  9. 2-D Acousto-Optic Signal Processors for Simultaneous Spectrum Analysis and Direction Finding

    DTIC Science & Technology

    1990-11-01

    National Dfense Defence nationale 2-D ACOUSTO - OPTIC SIGNAL PROCESSORS FOR SIMULTANEOUS SPECTRUM ANALYSIS 00 AND DIRECTION FINDING (U) by NM Jim P.Y...Wr pdft .1w I0~1111191 3 05089 National DIfense Defence nationale 2-D ACOUSTO - OPTIC SIGNAL PROCESSORS FOR SIMULTANEOUS SPECTRUM ANALYSIS AND DIRECTION...Processing, J.T. Tippet et al., Eds., Chapter 38, pp. 715-748, MIT Press, Cambridge 1965. [6] A.E. Spezio," Acousto - optics for Electronic Warfare

  10. European Military and Political Environment in a Post Cold War Era

    DTIC Science & Technology

    1992-06-01

    Fondation Inglehart, Ronald. CultureShiftinAdvancedlndustrialSociety. Nationale des Sciences Politiques , 1978), 104. Princeton: Princeton University Press...Nationale des Ladd, Everett Carll. Examining the American Idea of Nation. Sciences Politiques , 1978), 138. Paper presented to the Congress of the...Paris: Seuil, 1987: 87-116. Politiques , 1978. Rose, Richard. "National Pride in Cross-National Perspective." Csepeli, Gyorgy. "Negative Identity in

  11. Freeing France: The Allies, the Resistance, and the JEDBURGHs

    DTIC Science & Technology

    2008-01-01

    Lendemains Qui Déchantent: Le Parti Communiste Français À La Libération ([Paris, France]: Presses de la Fondation nationale des sciences politiques ...Province À La Liberation: Les Commissaires De La République, 1943-1946, Travaux Et Recherches De Science Politique ; 32. Paris: Fondation Nationale...des Sciences Politiques , 1975. 180 Kriegsmarine headquarters in Berlin, in actual practice, commanded their air and naval forces in France so not

  12. Organization of the Integrated Photonics Topical Meeting Held in Victoria, British Columbia on 30 March-1 April 1998. Technical Digest Series. Volume 4. Postconference Edition

    DTIC Science & Technology

    2007-11-02

    four- wave mixing characteristics of X./4-sn,fted DFB lasers, Jacques W.D. Chi, Jean Le Bihan, Ecole Nationale d’Inginieurs de Brest, France; K... Jacques W. D. CHI, K. Alan SHORE* and Jean LE BIHAN Ecole Nationale d’Ingenieurs de Brest, Laboratoire RESO Technopöle Brest-Iroise, C.P. 15,29608 BREST...Texas Instruments, USA Kunishige Oe, NTT Opto-electronics Laboratories, Japan Claude Rolland, Nortel Technology, Canada Jean -Francois Vinchant

  13. Combating the Influence of Non-State Organizations’ Deep Reach: Understanding the Expanded Influence of Non-State Actors and the Methodologies Required to Counter their Future Growth

    DTIC Science & Technology

    2013-05-23

    RELEASE; DISTRIBUTION IS UNLIMITED (]’ AB~TRACT (Maximum 200 words) ver t e years, organizations such as the Hezbollah, the liberation Tigers of Tamil ...of Tamil Eelam (LTTE), and the Algerian Front de Libération Nationale (FLN) have provided examples of successful frameworks for the development of...Tigers of Tamil Eelam (LTTE) ..................................................................... 22 Algerian Front de Libération Nationale (FLN

  14. Severe Weather Guide - Mediterranean Ports. 3. Catania

    DTIC Science & Technology

    1988-03-01

    COPIES FROM THE DEFENSE TECHNICAL INFORMATION CENTER. ALL OTHERS SHOULD APPLY TO THE NATIONAL TECHNICAL INFORMATION SERVICE . 1, UNCLASSIFIED I REPORT...5UB, ENGLAND METEOROLOGIE NATIONALE SERVICE HYDROGRAPHIQUE ET METEOROLOGIE NATIONALE SMM/DOCUMENTATION OCEANOGRAPHIQUE DE LA MARINE 1 QUAI BRANLY 2... nation provides insight as to how long before a change L4 1b e expe ed. lhe local wave directiun information .OUld 15e of uLe in selecting anchorage

  15. ESMC

    ScienceCinema

    None

    2016-07-12

    Workshops de 2 jours au Cern: 1.partie: communication scientifique: plusieurs discours suivis de questions et intenses discussions: 1.François de Closet "le progrès scientifique" 2.Gerhard Moosleiter(?) exposé avec dias et questions 3.H.Meyers "comment créer de meilleures conditions en communication scientifique 2.partie: science et communication :présentation des dias et questions. Une Russe de Moscou parle entre autre de la situation actuelle de la presse scientifique en Russie 3.partie: conclusions et rapports de la veille de differents groupes de travail 4.partie:questions avec C.Rubbia et N.Calder et remerciements

  16. Laser Annealing of Ion Implanted Semiconductors.

    DTIC Science & Technology

    1984-07-01

    I’Universiti Pierre et Marie Curie associi au Centre National de la Recherche Scientifique, 4 Place Jussieu, F- 75230 Paris Cedex 05, France (Received 15...Laboratoire de Physique des Solides, associi au Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie, Tour 13, Deuxiime Etage, 4 Place...White and Peercy ( Academic Press), 1980, p. 156 12 J.M. Liu, R. Yen, H. Kurz and N. Bloembergen :Appl. Phys. Lett. 39, 755 (1981) 13 G.A. Rozgonyi

  17. Characterization and Fate of Gun and Rocket Propellant Residues on Testing and Training Ranges: Interim Report 2

    DTIC Science & Technology

    2010-12-01

    Recherche Scientifique Centre Eau, Terre, et Environnement 290, de la Couronne Québec, Québec G1K 9A9 CANADA Peter Woods British Army Training...series of large-column tests have been completed at Institut National de la Recherche Scientifique – Eau, Terre et Environnement . The columns were...participated in the spring sampling. Dr. Susan Taylor provided the magnified images of the propel- lant segments. Internal manuscript review was

  18. Science Town 2.0: An integrating Concept for S&T Support for Multi-Agency Crisis and Disaster Management

    DTIC Science & Technology

    2012-12-01

    sécurité et de défense par la mise en place d’une « ville scientifique » mobile. La réussite du déploiement des capacités CBRNEJ a accéléré...judiciaires (CBRNEJ) ont été mobilisées à l’appui des opérations de sécurité et de défense par la mise en place d’une « ville scientifique » mobile. La...l’intérieur d’une validation de concept de ville scientifique 2.0. vi DRDC CSS TM 2012-029 Table of contents Abstract

  19. Multiscale Materials Science: A Mathematical Approach to the Role of Defects and Uncertainty

    DTIC Science & Technology

    2015-03-01

    ADDRESS(ES) Ecole Nationale des Ponts et Chaussees 6 et 8 avenue Blaise Pascal , Cite Descartes, Champs sur Marne 77 455 Marne la Vallee Cedex 2...nationale des ponts et chaussees 6 et 8 avenue Blaise - Pascal , Cite Descartes Champs-sur-Marne F-77455 Mame-la-Vallee cedex 2 www.enpc.fr tel...CHAUSSEES 6, AVENUE BLAISE PASCAL 6 ET 8 CITE DESCARTES CHAMPS SUR MARNE, 77420 FR 13d. BUSINESS OFFICE CONTACT: CAROLINA GARCIA-OLMEDO 13e

  20. Multiscale Problems in Materials Science: A Mathematical Approach to the Role of Uncertainty

    DTIC Science & Technology

    2012-10-01

    Claude Lebris, F. Legoll, F. Thomines Ecole Nationale des Ponts et Chaussées 6-8, Avenue Blaise Pascal Marne la Vallée 77455, France...5d. TASK NUMBER 5e. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Ecole Nationale des Ponts et Chaussées 6-8, Avenue Blaise ... Pascal Marne la Vallée 77455, France 8. PERFORMING ORGANIZATION REPORT NUMBER N/A 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS

  1. Preface: Materiaux 2010

    NASA Astrophysics Data System (ADS)

    Cheikhrouhou, Abdelwaheb

    2012-02-01

    , Faculté des Sciences d'El Jadida (Morocco) M.H. BEN GHOZLEN, Faculté des Sciences de Sfax (Tunisia) R. BENNACEUR, Faculté des Sciences de Tunis (Tunisia) B. BENYOUCEF, Université Abou Bakr Belkaid, Tlemcen (Algeria) M. BEN SALEM, Faculté des Sciences de Bizerte (Tunisia) B. BESSAIES, Centre de Recherches et Technologies de l'Energie (Tunisia) H. BOUCHRIHA, Faculté des Sciences de Tunis (Tunisia) W. BOUJELBEN, Faculté des Sciences de Sfax (Tunisia) A. CHEIKHROUHOU, Faculté des Sciences de Sfax (Tunisia) W. CHEIKHROUHOU-KOUBAA, Faculté des Sciences de Sfax (Tunisia) R. CHTOUROU, Centre de Recherches et Technologies de l'Energie (Tunisia) M. DEBBABI, Ecole Nationale d'Ingénieurs de Monastir (Tunisia) A. DAKHLAOUI, Faculté des Sciences de Bizerte (Tunisia) A. DINIA, Université de Strasbourg (France) B. ELJANI, Faculté des Sciences de Monastir (Tunisia) A. ELJAZOULI, Faculté des Sciences Ben Msik, Casablanca (Morocco) Z. FAKHFAKH, Faculté des Sciences de Sfax (Tunisia) A. GASMI, Faculté des Sciences d'Annaba (Algeria) A. GHARBI, Faculté des Sciences de Tunis (Tunisia) R. GHARBI, Faculté des Sciences de Sfax (Tunisia) K. GUIDARA, Faculté des Sciences de Sfax (Tunisia) H. GUERMAZI, Institut Préparatoire aux Etudes d'Ingénieurs de Sfax (Tunisia) S. GUERMAZI, Faculté des Sciences de Sfax (Tunisia) M. HADDAD, Faculté des Sciences de Meknès (Morocco) A. HAJ AMARA, Faculté des Sciences de Bizerte (Tunisia) D. HAMANA, Faculté des Sciences de Constantine (Algeria) N. KAMOUN, Faculté des Sciences de Tunis (Tunisia) S. KADDOUR-CHARFI, Faculté des Sciences de Tunis (Tunisia) M. KADDOUR, Faculté des Sciences de Sfax (Tunisia) M. KHITOUNI, Faculté des Sciences de Sfax (Tunisia) T. MHIRI, Faculté des Sciences de Sfax (Tunisia) Y. MLIK, Institut Préparatoire aux Etudes Scientifiques et Techniques (Tunisia) N. MLIKI, Faculté des Sciences de Tunis (Tunisia) A. NJAH, Faculté des Sciences de Gafsa (Tunisia) M. OUESLATI, Faculté des Sciences de Tunis (Tunisia) K

  2. Perrotin et la meilleure mesure française de la vitesse de la lumière

    NASA Astrophysics Data System (ADS)

    Bogaert, G.; Blanc, W.

    2012-12-01

    à la fin du 19ème siècle, la détermination de la vitesse de la lumière a fait l'objet d'une controverse scientifique impliquant d'éminents scientifiques français et américains : Alfred Cornu et Hippolyte Fizeau, d'un côté, Simon Newcomb et Albert Michelson de l'autre. Cette controverse prendra fin de façon inattendue avec les deux mesures réalisées en 1898 et 1902 par Henri Perrotin, le directeur de l'Observatoire de Nice.

  3. 21 CFR Appendix B to Subpart A of... - List of Authorities

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Control Farmacéutico. For medicinal products for veterinary use: Ministerio de Agricultura, Pesca y...: Agence du Médicament. For veterinary medicinal products: Agence Nationale du Médicament Vétérinaire..., Dipartimento Farmaci e Farmacovigilanza. For medicinal products for veterinary use: Ministero della...

  4. Civil-Military Relations During Coalition Operations in the Balkans

    DTIC Science & Technology

    2001-05-01

    no. 4 (October 1997), 94; and General Jean Cot, French Army, “Dayton ou la Porte Etroite: Genese et Avenir d’un Desastre ,” in Derniere Guerre...Defense Nationale 53, no. 4 (October 1997), 94; and General Jean Cot, French Army, “Dayton ou la Porte Etroite: Genese et Avenir d’un Desastre ,” in

  5. German Unification: Security Implications for Europe

    DTIC Science & Technology

    1990-07-01

    director of the Institut Francais des Relations Inter’nationales and editor of its journal, Politique Etrangere. ="Memorandum of the Ministry of Foreign...ecoloaical endeavors have spent most of the ’-=ea• e dividend ’ that resulted from the dramatic reduction in zhe armed forces of the nations of Europe. the

  6. Mikhail Gorbachev’s ’New Thinking’ Implications for Western Security

    DTIC Science & Technology

    1991-06-01

    less pessimistic appraisal of Gorbachev’s reforms. Pierre Hassner, research director at Paris’s Fondation Nationale des Sciences Politiques ...promise of future dividends in the form of improved technologies provided by a revived and more vigorous Soviet economy. Petersen and Trulock state that

  7. Design of Synthetic Aperture Sonar Systems for High-Resolution Seabed Imaging (Tutorial Slides)

    DTIC Science & Technology

    2006-10-01

    born in Wellington, India in 1960. He graduated from the Ecole Nationale des Ponts et Chaussées, Paris (France) in 1983. From 1985 to 1989 and 1989 to...NURC 75 SAS image & coherence map NATO Undersea Research Centre 39 Tutorial presented at Oceans’06 © NURC 76 Bathymetric map Tutorial presented at

  8. Teacher and Administrator Evaluation. Bibliographies in Education. No. 74.

    ERIC Educational Resources Information Center

    Moll, Marita

    This annotated bibliography contains 602 references on teacher and administrator evaluation appearing, between May 1975 and September 1981, in: (1) Bibliographie du Quebec (Bibliotheque nationale du Quebec); (2) British Education Index (British Library); (3) Canadian Books in Print (University of Toronto Press); (4) Canadian Education Index; (5)…

  9. Soldier Integrated Headwear System: System Design Process

    DTIC Science & Technology

    2006-10-01

    Nationale Canada Abstract The aim of the Soldier Integrated Headwear System –Technology Demonstration Project (SIHS-TDP) is to empirically...determine the most promising headwear integration concept that significantly enhances the survivability and effectiveness of the future Canadian

  10. International Meeting on Business Start-up (Lille, France, November 26-28, 1992).

    ERIC Educational Resources Information Center

    Melis, Africa, Ed.; Peigne, Florence, Ed.

    1992-01-01

    An international meeting explored work on business start-up undertaken jointly by CEDEFOP (European Centre for the Development of Vocational Training) and France's Agence Nationale pour la creation d'entreprise. One opening presentation (Melis) addressed the basic idea underlying the research: to identify and highlight the role of training and…

  11. China Report, Economic Affairs

    DTIC Science & Technology

    2007-11-02

    Banque Indosuez, Standard Chartered Bank and Societe Generale. Speaking after yesterday’s opening ceremony of Societe Generale’s Zhenzhen branch, Mr...Luo said China had not yet approved an application from Banque Nationale de Paris to upgrade its representative office to branch status. But banking

  12. [Moyse Charas, an apothecary, a physician, as well as the author of "Pharmacopée royale galénique et chymique". The study of his dynasty].

    PubMed

    Warolin, Christian

    2005-01-01

    New research works conducted at the Archives nationales led to the discovery of numerous documents related to Moyse Charas's progeny and made it possible to complete former studies. Presently the filiation of this famous family of Parisians apothecaries of the seventeenth and eighteenth centuries is well established. A family tree has been drawn up.

  13. A Survey of Modern Air Traffic Control. Volume 2

    DTIC Science & Technology

    1975-07-01

    oceanic traffic would use combined hyperbolic-inertial navigation systems. System I could be implemented to meet the demanda for air traffic services...of Aviation c/o Flugrad Reykjavik ITALY Aeronautica Militare Ufficio del Delegato Nationale all’AGARD 3, Piazzale Adenauer Roma /EUR

  14. Missile Aerodynamics (Aerodynamique des Missiles)

    DTIC Science & Technology

    1998-11-01

    guerre froide la production des missiles a baisse’, avec pour consequence une diminution des budgets de d6veloppement. Les nouveaux types de conflits ...Roma) Directeur - Gestion de l’information LUXEMBOURG (Recherche et developpement) - DRDGI 3 Voir Belgique Ministbre de la Difense nationale NORVEGE

  15. Cultural Dimensions of Digital Library Development, Part I: Theory and Methodological Framework for a Comparative Study of the Cultures of Innovation in Five European National Libraries

    ERIC Educational Resources Information Center

    Dalbello, Marija

    2008-01-01

    This study examines the influence of culture on digital libraries of the first wave. The local cultures of innovation of five European national libraries (Biblioteca nacional de Portugal, Bibliotheque nationale de France, Die Deutsche Bibliothek, the National Library of Scotland, and the British Library) are reconstructed in case histories from…

  16. Cultural Dimensions of Digital Library Development, Part II: The Cultures of Innovation in Five European National Libraries (Narratives of Development)

    ERIC Educational Resources Information Center

    Dalbello, Marija

    2009-01-01

    This article presents the narrative accounts of the beginnings of digital library programs in five European national libraries: Biblioteca nacional de Portugal, Bibliotheque nationale de France, Die Deutsche Bibliothek, the National Library of Scotland, and the British Library. Based on interviews with policy makers and developers of digital…

  17. Unpublished manuscripts of Sophie Germain and a revaluation of her work on Fermat's Last Theorem

    NASA Astrophysics Data System (ADS)

    Del Centina, Andrea

    2008-07-01

    Published, and discussed, are some manuscripts and a letter of Sophie Germain concerning her work on Fermat's Last Theorem. These autographs, held at Bibliothèque Nationale, Paris, at the Moreniana Library, Florence, and at the University Library, Göttingen, contribute to a substantial revaluation of her work on this subject.

  18. Dynamical Segmentation of the Left Ventricle in Echocardiographic Image Sequences

    DTIC Science & Technology

    2007-11-02

    Solaiman 1, C. Roux 1. 1Ecole Nationale Supérieure des Télécommunications de Bretagne , Brest, France 2Centro de Procesamiento de Imágenes... Bretagne , Brest, France Performing Organization Report Number Sponsoring/Monitoring Agency Name(s) and Address(es) US Army Research, Development

  19. Senegal: The Economic Reforms and the Influence of the Informal Sector on the Economic Reform Process

    DTIC Science & Technology

    2002-06-01

    effects are not. Although the government established an agricultural development bank (la Caisse Nationale de Crédit), farmers could not afford...average in other African countries, which was 44%. Successive positive real growth did not compensate for the sacrifices the people made. Poverty

  20. Langues et education en Afrique noire (Language and Education in Black Africa).

    ERIC Educational Resources Information Center

    Bearth, Thomas, Ed.

    1997-01-01

    Papers on language and education in Black Africa include: "L'enseignement des et en langues nationales au Zaire. Bilan d'une experience" ("The Teaching of and in National Languages in Zaire. Results of an Experiment") (Andre Mbula Paluku); "Langues et education au Rwanda" ("Languages and Education in…

  1. IFLA General Conference, 1985. Division of Bibliographic Control. Sections on Bibliography, Cataloging, and Classification. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on cataloging and classification which were presented at the 1985 International Federation of Library Associations (IFLA) conference include: (1) "Online Cataloging at the Bibliotheque Nationale (Francoise Finelli and Serge Salomon, France); (2) "Development of National Press Repertoire in the Condition of Multinational State: Its…

  2. Modelling and Simulation for Requirements Engineering and Options Analysis

    DTIC Science & Technology

    2010-05-01

    Defence, 2010 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2010 DRDC Toronto CR 2010...externalize their mental model of the assumed solution for critique and correction by others, and whether or not this would assist in ensuring that

  3. Cumulative Viral Load and Virologic Decay Patterns after Antiretroviral Therapy in HIV-Infected Subjects Influence CD4 Recovery and AIDS

    DTIC Science & Technology

    2011-05-20

    study). The Antiproteases Cohorte Agence Nationale de Recherches sur le SIDA EP 11 study. J Infect Dis 186: 710–714. 8. Hermankova M, Ray SC, Ruff C... Sida (ANRS) CO3 Aquitaine Cohort. Clin Infect Dis 49: 1109–1116. 59. Choi AI, Shlipak MG, Hunt PW, Martin JN, Deeks SG (2009) HIV-infected persons

  4. Eco-hydrology: Groundwater flow and site factors in plant ecology

    NASA Astrophysics Data System (ADS)

    Klijn, Frans; Witte, Jan-Philip M.

    Résumé En écologie végétale, le site est un concept central. Un site, c'est l'endroit où une espèce végétale ou une communauté de plantes se développe le site assure un ensemble de conditions dans lesquelles elles vivent. Dans un matériau homogène à l'origine, l'écoulement gravitaire d'une nappe influence les conditions du site par l'intermédiaire de la distribution spatiale des nutriments et d'autres composés chimiques associés. Les remontées d'eau peuvent tout spécialement produire et maintenir les conditions du site essentielles pour différentes espèces et communautés de plantes relativement rares. Les écologues ont porté une attention accrue à ces remontées d'eau, en sorte qu'une coopération avec les hydrologues en a résulté, avec l'émergence d'une discipline propre, l'éco-hydrologie, à la limite des deux domaines scientifiques et liée au concept de site. Aux Pays-Bas, une classification des types d'eau, basée sur l'histoire de l'eau souterraine à proximité de la surface, a été mise en oeuvre pour constituer une base nationale de données géographiques sur les remontées d'eau d'intérêt écologique. Des analyses des correspondances des données de cette base, portant sur l'existence de certaines espèces de plantes, montrent que dans les sols sableux pauvres du Pléistocène la remontée d'eau explique très bien la présence de certaines espèces et communautés, alors que, dans les plaines fluviales et les régions de polders à sols argileux riches, l'influence de la remontée d'eau est masquée par l'importance des caractéristiques des sols. En conclusion donc, certaines espèces de plantes peuvent être utilisées comme des indicateurs de la remontée d'eau dans des diagnostiques et des levés de terrain rapides, mais à condition de prendre en permanence des précautions sur les limites de l'approche. Resumen En ecología botánica un concepto de gran importancia es el de emplazamiento, definido como el lugar que

  5. FOREWORD: The 5th International Colloquium on Atomic Spectra and Oscillator Strengths for Astrophysical and Laboratory Plasmas

    NASA Astrophysics Data System (ADS)

    Tchang-Brillet, Wad Lydia; Wyart, Jean-François; Zeippen, Claude

    1996-01-01

    and astronomy have a long common history. Indeed, we are reminded that a century ago, terrestrial and solar helium were identified with one another through spectral lines, while recent studies of nebulae and the interstellar medium provide nice examples of the continuing interplay between spectroscopy and astrophysical models. During the Amsterdam meeting, some astrophysicists deplored that the so-called "traditional term analysis" was disappearing. They should be reassured about the near future owing to three invited papers and a great number of posters on this type of work. We are grateful to the members of the Scientific Committee who helped us to set up the scientific programme and to all the referees who reviewed the manuscripts published in this volume. We thank the Observatoire de Paris-Meudon, the Centre National de la Recherche Scientifique and the Centre National d'Etudes Spatiales for financial support. We also thank the Ministère de l'Education Nationale, de l'Enseignement Supérieur, de la Recherche et de l'Insertion Professionnelle, the National Aeronautics and Space Administration and the Laboratoire Aimé Cotton for providing travel grants, Further support from SUN Microsystems, Alcatel and Crédit Lyonnais is gratefully acknowledged. The colloquium greatly benefited from the infrastructure of the Observatoire de Paris-Meudon and the cooperation of its staff, especially members of the Département Atomes, Molécules en Astrophysique (DAMAp). The 6th International Colloquium on Atomic Spectra and Oscillator Strengths for Astrophysical and Laboratory Plasmas is scheduled to be held in Victoria, Canada in 1998.

  6. Female genital cosmetic surgery.

    PubMed

    Shaw, Dorothy; Lefebvre, Guylaine; Bouchard, Celine; Shapiro, Jodi; Blake, Jennifer; Allen, Lisa; Cassell, Krista; Leyland, Nicholas; Wolfman, Wendy; Allaire, Catherine; Awadalla, Alaa; Best, Carolyn; Dunn, Sheila; Heywood, Mark; Lemyre, Madeleine; Marcoux, Violaine; Menard, Chantal; Potestio, Frank; Rittenberg, David; Singh, Sukhbir; Shapiro, Jodi; Akhtar, Saima; Camire, Bruno; Christilaw, Jan; Corey, Julie; Nelson, Erin; Pierce, Marianne; Robertson, Deborah; Simmonds, Anne

    2013-12-01

    Objectif : Fournir aux gynécologues canadiens des directives factuelles en matière de chirurgie esthétique génitale chez la femme, en réponse au nombre grandissant de demandes (et d’interventions) de chirurgie vaginale et vulvaire se situant bien au-delà des reconstructions traditionnellement indiquées sur le plan médical. Résultats : La littérature publiée a été récupérée par l’intermédiaire de recherches menées dans PubMed ou MEDLINE, CINAHL et The Cochrane Library en 2011 et en 2012 au moyen d’un vocabulaire contrôlé et de mots clés appropriés (« female genital cosmetic surgery »). Les résultats ont été restreints aux analyses systématiques, aux essais comparatifs randomisés / essais cliniques comparatifs et aux études observationnelles. Aucune restriction n’a été appliquée en matière de date ou de langue. Les recherches ont été mises à jour de façon régulière et intégrées à la directive clinique jusqu’en mai 2012. La littérature grise (non publiée) a été identifiée par l’intermédiaire de recherches menées dans les sites Web d’organismes s’intéressant à l’évaluation des technologies dans le domaine de la santé et d’organismes connexes, dans des collections de directives cliniques, dans des registres d’essais cliniques et auprès de sociétés de spécialité médicale nationales et internationales. Valeurs : La qualité des résultats est évaluée au moyen des critères décrits dans le rapport du Groupe d’étude canadien sur les soins de santé préventifs (Tableau). Recommandations 1. Un des rôles importants des obstétriciens-gynécologues devrait consister à aider les femmes à comprendre leur anatomie et à en respecter les variantes qui leur sont propres. (III-A) 2. Lorsqu’une femme demande la tenue d’interventions esthétiques vaginales, une anamnèse médicale, sexuelle et gynécologique exhaustive devrait être obtenue et l’absence de tout dysfonctionnement

  7. Relevé postnatal Rourke 2014

    PubMed Central

    Riverin, Bruno; Li, Patricia; Rourke, Leslie; Leduc, Denis; Rourke, James

    2015-01-01

    Résumé Objectif Mettre à jour la version de 2011 du Relevé postnatal Rourke (RPR) à la suite d’une révision des meilleures données probantes récentes sur le suivi de la santé des nourrissons et des enfants de la naissance jusqu’à l’âge de 5 ans. Qualité des données La qualité des données a été cotée en fonction de l’ancien système de classification du Groupe d’étude canadien sur les soins de santé préventifs (jusqu’à 2006) et l’approche de détermination, d’élaboration et d’évaluation des recommandations (GRADE). Message principal De nouveaux faits scientifiques ont été pris en compte dans les recommandations du RPR 2014 en ce qui a trait au suivi de la croissance, à la nutrition, à l’éducation et aux conseils, au développement, à l’examen physique et à l’immunisation. La croissance est surveillée à l’aide des courbes de l’Organisation mondiale de la Santé qui ont été révisées en 2014. On devrait introduire les aliments solides en fonction de l’état de préparation du nourrisson et ces produits devraient contenir du fer. Il n’est actuellement plus recommandé de retarder l’introduction des allergènes alimentaires courants pour prévenir les allergies. Il faut promouvoir l’utilisation d’une tasse sans couvercle au lieu d’une tasse à bec dès l’âge de 12 mois. La section sur l’éducation et les conseils porte sur les blessures causées par du mobilier instable, ainsi que l’utilisation d’un siège d’auto orienté vers l’arrière jusqu’à 2 ans. Elle comporte aussi de l’information sur les saines habitudes de sommeil, la prévention de la maltraitance des enfants, la vie saine et active et la sédentarité de la famille, de même que l’hygiène buccale. On a aussi ajouté à cette section une nouvelle catégorie consacrée à la santé environnementale pour tenir compte des effets des dangers environnementaux sur la santé des enfants. Le RPR a recours à une

  8. Language of Information Science: Convertibility in Information Science

    DTIC Science & Technology

    The report is the result of a study of the language of information science based on the terminology contained in a collected set of lexical resources...Groupe d’Etude sur l’Information Scientifique’, selected because it represents an international concensus of the domain of information science . A

  9. France Sets Out to Democratize Science.

    ERIC Educational Resources Information Center

    Dickson, David

    1982-01-01

    Discusses proposed governmental science policy reforms, including administrative reforms of Centre National de la Recherche Scientifique, French equivalent to National Science Foundation. Indicates junior scientists, lab assistants, and technicians will be included in decision making and scientists will be barred from heading research terms for…

  10. Passion Research: A Joint Venture To Interest High School Students in Chemistry.

    ERIC Educational Resources Information Center

    Carriere, Francois J.; Abouaf, Madeleine

    1997-01-01

    Describes a joint venture between the Centre National de la Recherche Scientifique (CNRS) and the Department of Education in France that was created to allow students to do practical scientific work with the help of a CNRS researcher. Presents two practical projects done by students on organic polymers and on color. Concludes that this increases…

  11. Guides to Aerospace Research and Development in NATO Countries.

    DTIC Science & Technology

    1984-01-01

    Documentation Scientifique analysis centers, research coordinating offices in agriculture, art, business, education , et Technique, Brussels (Belgium). (In...Direty. Martin. J. (ed.). American Association of Small The guide indudes information on pure and applied siences , engineering, medicine, Research...Constitution, the Armed Forces, educational institutions, under which research units operate. The Institutional Index directs the user to a libraries

  12. Documenting and Researching Endangered Languages: The Pangloss Collection

    ERIC Educational Resources Information Center

    Michailovsky, Boyd; Mazaudon, Martine; Michaud, Alexis; Guillaume, Séverine; François, Alexandre; Adamou, Evangelia

    2014-01-01

    The Pangloss Collection is a language archive developed since 1994 at the Langues et Civilisations à Tradition Orale (LACITO) research group of the French Centre National de la Recherche Scientifique (CNRS). It contributes to the documentation and study of the world's languages by providing free access to documents of connected, spontaneous…

  13. Memorial I.Rabi

    ScienceCinema

    None

    2016-07-12

    Le DG H.Schopper ainsi que Norman Ramsey et le DG de l'Unesco rendent hommage à Isidor Rabi, grand scientifique et humaniste (1929-1988).Cette rencontre est organisée ensemble avec le Cern et l'Unesco.

  14. Clinical and Epidemiological Studies on Rickettsial Infections

    DTIC Science & Technology

    1978-10-01

    hosts of vector mites in Malaysia. J.Med.Ent. 2(2):153-156. GIROU11, P., 1950. Une mission scientifique au moyen Congo, en Oubangui ou Ruanda - A...ori- entalis chez les indigenes et des asiatiques vivant au Ruanda -Urundi (Congo Belge). Bull.Soc.Path.exot. 44:50-51. GISPEN, R., 1950. The virus of

  15. Topical Meeting on Laser Techniques for Extreme Ultraviolet Spectroscopy, 8-10 March 1982, Boulder, Colorado.

    DTIC Science & Technology

    1982-03-01

    Excited States In Molecules, Jacques Lukasik, Stephen C. Wallace* and William R. Greent, Laboratoire d’Optique Quantique du Centre Na- tional de /a...MOLECULES Jacques LUKASIK, Stephen C. WALLACE(a) and William R. GREEN(b) Laboratoire d’Optique Quantique du Centre National de la Recherche Scientifique

  16. Fleischmann seminar (fusion)

    ScienceCinema

    None

    2016-07-12

    "pictures, television out, no flash and camera, there will be a press section later on in the council room if Prof. Fleischmann will accept"..le DG C.Rubbia insiste pour cette discussion scientifique de ne pas filmer, autrement de bien quitter la salle, ce qui provoque un petit remue-ménage...

  17. Indexation Rules for Metallurgy in PASCAL. Original Title: Regles d'Indexation de la Metallurgie'--Technical Note Issued by Informascience--January 1980. Translated by Marie Wallin.

    ERIC Educational Resources Information Center

    Royal Inst. of Tech., Stockholm (Sweden). Library.

    The indexing rules presented are designed for use with a new French-German database on metallurgy being developed under an agreement by CNRS (Centre National de la Recherche Scientifique, Paris) and BAM (Bundesanstalt fur Materialprufung, Berlin). The new database, which will feature multilingual titles and index terms (French-German-English-) and…

  18. Press conference

    ScienceCinema

    None

    2016-07-12

    Exposés de plusieurs intervenants de la direction et du conseil, comme le Prof.Ramsey, président du conseil sur l'adhésion récente de la Finlande et le "boom" scientifique des pays de l'est.

  19. Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (13th, Paris, France, July 9-13, 1989), Volume 1.

    ERIC Educational Resources Information Center

    International Group for the Psychology of Mathematics Education.

    This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following papers: "Transformations Accelerees de l'Education Scientifique Pendant la Revolution Francaise" (Jean Dhombres); "Building on the Knowledge of Students and Teachers" (Thomas P. Carpenter & Elizabeth…

  20. The Axially Symmetric Potential Flow About Elognated Bodies of Revolution

    DTIC Science & Technology

    1951-08-01

    Another exact method, based on a distribution of vorticity over the surface of the body, is being developed by )r. Vandry of the Admiralty Re- search...34Ecoulement potentiel autour d’un corps de revolution," Colloques Internationaux du Centre National de la Recherche Scientifique, XIV, Mithodes de Calcul dans

  1. Major Events Coordinated Security Solutions Technical Report Closeout (MECSS): The Application of Science and Technology to Reduce Risk for V2010 and G8/G20 Summits

    DTIC Science & Technology

    2010-12-01

    professionnalisme de plus de 180 scientifiques, technologues et autres professionnels de RDDC ainsi que d’autres ministères et organismes fédéraux...Key coordination effort includes determining objectives, establishing the appropriate competence , authority and responsibility constructs, and

  2. Memorial I.Rabi

    SciTech Connect

    2006-11-01

    Le DG H.Schopper ainsi que Norman Ramsey et le DG de l'Unesco rendent hommage à Isidor Rabi, grand scientifique et humaniste (1929-1988).Cette rencontre est organisée ensemble avec le Cern et l'Unesco.

  3. Conference on the Physics, Chemistry and Biology of Water (3rd) Held in West Dover, Vermont on October 16-19, 2008 (Abstracts)

    DTIC Science & Technology

    2008-10-27

    confinement, photocatalytic water splitting, recyclable hydrogen, thermoluminescence , nanofluids, nanochannels. aqueous hydroxide ion transport, IR...Conseiller Scientifique Thermoluminescence as an experimental tool to investigate the ’ structure’ of high dilutions 10:10 Vittorio Elia Univ... Thermoluminescence as an experimental tool to investigate the " structure " of High Dilutions : Glimpses into the potential role of the gas phase during

  4. Microphysical and Electrical Modeling of Convective Clouds.

    DTIC Science & Technology

    1995-04-01

    Program, AK-50, Seattle, WA 98195, USA. VWrifi6 par P. Laroche, Chef de la Division "Environnement Atmospherique " Vu et approuv6, Le Directeur Scientifique...storm cells on a new one growing, we can introduce in our model a "seeding effect": the new cell develops in an atmosphere polluted by small ice crystals

  5. [Heroin seized in France. Statistical data from National database of Forensic Laboratories].

    PubMed

    Dujourdy, L; Besacier, F

    2010-03-01

    This article aims at exploiting the statistical data of the qualitative and quantitative analyses of heroin circulating in France over more than 20 years. This information, systematically recorded by the Forensic Laboratories from Institut national de police scientifique is a good source of knowledge of this product at both the chemical and sanitary levels (street level, wholesalers, imports, etc.).

  6. Le changement comme tradition dans la recherche et la formation a la recherche en biotechnologie et en peripherie Etude de cas en sciences de la sante, sciences naturelles et genie

    NASA Astrophysics Data System (ADS)

    Bourque, Claude Julie

    Le champ de la recherche scientifique et de la formation a la recherche est traverse depuis quelques dizaines d'annees par plusieurs courants et discours associes au changement, mais peu de travaux empiriques permettent de comprendre ce qui change concretement. C'est la contribution originale de cette these au champ de l'education, plus specifiquement a l'etude sociologique de l'enseignement superieur ou sont concentrees les activites liees a la triade thematique du programme doctoral dans lequel elle a ete produite : recherche, formation et pratique. L'enquete-terrain a ete realisee en 2009 et 2010 aupres de 808 repondants affilies a 60 etablissements au Quebec et a produit un vaste materiau de nature mixte (donnees quantitatives et qualitatives). Un portrait de la nebuleuse biotechnologique qui touche les secteurs des sciences de la sante, des sciences naturelles et du genie a ete realise. Ce domaine concerne des dizaines de disciplines et se revele de nature transdisciplinaire, mais les pratiques n'y sont pas davantage marquees par le changement que celles d'autres domaines connexes. Les dynamiques sociales ont fait l'objet d'analyses comparatives dans quatre contextes: le choix des programmes, des objets et des methodes, le financement, la diffusion et la planification de la carriere. Les resultats indiquent que les echanges entre les agents traditionnellement situes au coeur des activites de recherche dominent ces dynamiques dans tous les contextes etudies. L'etude des representations au fondement des pratiques a revele l'existence de trois ecoles de pensee qui coexistent dans le champ scientifique: academique, pragmatique et economiste. Ces ecoles permettent de categoriser les agents en fonction des zones de fractures qui marquent leurs oppositions tout en identifiant ce qu'ils ont en commun. Les representations et les pratiques liees a la formation temoignent d'un habitus plutot homogene, alors que les contradictions semblent plus souvent ancrees dans des

  7. Acousto-Optic Spectrum Analyzer: Temporal Response and Detection of Pulsed Signals.

    DTIC Science & Technology

    1986-12-01

    ACOUSTO - OPTIC SPECTRUM ANALYZER: TEMPORAL RESPONSE AND I/i DETECTION OF PULSED SIGUALS(U) DEFENCE RESEARCH ESTABLISHMENT OTTANA (ONTARIO) J...8217:. -.....:.-...............--.. - ---:-..--.-..,. ,: i’,.. IJT~c FILE C P National Defe’ se + Deence nationale 0 0 ACOUSTO - OPTIC SPECTRUM ANALYZER: TEMPORAL RESPONSE AND DETECTION 0 OF PULSED...Ottawa |S, .±~ |-----------------------..,---.-- -- - - - rNatiorna! Defen~se Deterice r dornale ACOUSTO - OPTIC SPECTRUM ANALYZER: TEMPORAL RESPONSE

  8. Discussion on the Modelling and Processing of Signals fom an Acousto-Optic Spectrum Analyzer.

    DTIC Science & Technology

    1987-06-01

    AD-AIBS 639 DISCUSSION ON THE MODELLING AND PROCESSIN OF SIGNALS 1/1 FOR RN ACOUSTO - OPTIC SPECTRUM ANALYZER(U)G DFENCE RESERCH ESTABGLISHMENT OTTANA...8217’~ AV - I National DefenseI Defence nationale DISCUSSION ON THE MODELLING AND PROCESSING OF SIGNALS FROM AN ACOUSTO - OPTIC SPECTRUM ANALYZER by Guy...signals generated by an Acousto - Optic Spectrum Analyzer (AOSA). It also shows how this calculation can be related to pulse modu- lated signals. In its

  9. Exploratory simulations of multiphase effects in gas injection and ventilation tests in an underground rock laboratory

    SciTech Connect

    Finsterle, S. . Versuchsanstalt fuer Wasserbau, Hydrologie und Glaciologie); Schlueter, E.; Pruess, K. )

    1990-06-01

    This report is one of a series documenting the results of the Nagra-DOE Cooperative (NDC-I) research program in which the cooperating scientists explore the geological, geophysical, hydrological, geochemical, and structural effects was sponsored by the US Department of Energy (DOE) through the Lawrence Berkeley Laboratory (LBL) and the Swiss Nationale Genossenschaft fuer die Lagerung radioaktiver Abfaella (Nagra) and concluded in September 1989. 16 refs., 29 figs., 4 tabs.

  10. Germany and the Future of Nuclear Deterrence in Europe

    DTIC Science & Technology

    1992-12-01

    European leaders can contemplate how to spend peace dividends . So goes the common view.’ The dissolution of the Soviet Union and the unification of...Coulisses de la politique dtrang~re sous la Ve Rdpublique (Paris: Hachette, 1986); quoted in Yost, Strategic Culture, 25. 76 been respected to date.󈧒 The...Lothar Ruihl, La politique militaire de la cinqui~me rdpublique (Paris: Foundation Nationale des Sciences Politiques , 190-191; quoted in David S. Yost

  11. Evaluation of Shelter Ventilation by Model Tests. Option 2

    DTIC Science & Technology

    1984-09-01

    HUMUERS, 7449 N. Natchez Ave. FEMPL Work Unit 12.171 Niles, Illinois 60648 II. CONTROLLING OFFICE NAME AND ADDRESS IL REPORT DATE Federal Emergency...lights could be controlled through a voltage regulator. These lights 2-1 GARD ELEVATION VIEW Earth Berm Wndow 3’ x 3’ Winindow Interior of Shelter 32...Nationale 1 36 Rue J. B. Esch Luxembourg (Grand-Duche) Ministero dell Interno 1 Director General Protectione Civile Rome, Italy Civile Emergency Planning

  12. LOCAT - A Data Retrieval Program.

    DTIC Science & Technology

    1984-12-01

    STANDARSIA1 3 -A Suznn Y4Sl ’ś’. Doc 0 006 U m Nalionai Deftense U’" Defence nationale LOCAT -A DATA RETRIEVAL PROGRAM by Suzanne Y. Slinn SA RSA T Project...2.1 DESIGN PHILOSOPHY...................2 2.2 SATELLITE AND LOCATION SOFT KEY DISPLAY .. .. ........ 3 2.3...LOCAT -Calling Sequence .. .. ...... ........ 2 FIGURE 2: SAT/LOC Soft Key Display .. .. ...... ..... 3 FIGURE 3 : Frequency Soft Key Display

  13. (Low-level radioactive waste management techniques)

    SciTech Connect

    Van Hoesen, S.D.; Kennerly, J.M.; Williams, L.C.; Lingle, W.N.; Peters, M.S.; Darnell, G.R.; USDOE Oak Ridge Operations Office, TN; Du Pont de Nemours and Co., Aiken, SC . Savannah River Plant; Idaho National Engineering Lab., Idaho Falls, ID )

    1988-08-08

    The US team consisting of representatives of Oak Ridge National Laboratory (ORNL), Savannah River plant (SRP), Idaho National Engineering Laboratory (INEL), and the Department of Energy, Oak Ridge Operations participated in a training program on French low-level radioactive waste (LLW) management techniques. Training in the rigorous waste characterization, acceptance and certification procedures required in France was provided at Agence Nationale pour les Gestion des Dechets Radioactif (ANDRA) offices in Paris.

  14. Discrimination Power Control for Adaptive Target Tracking Applications

    DTIC Science & Technology

    2008-07-01

    Discriminat ion power cont ro l fo r adaptive target tracking applications A. Benaskeur F. Rhéaume DRDC Valcartier Defence R&D Canada – Valcartier...Technical Report DRDC Valcartier TR 2008-016 July 2008 Discrimination power control for adaptive target tracking applications A. Benaskeur F...nationale, 2008 Abstract This report addresses the problem of discrimination power in target tracking applications . More specifically, a closed-loop

  15. The INSU and DMN network of ST radars

    NASA Technical Reports Server (NTRS)

    Petitdidier, M.; Klaus, V.; Baudin, F.; Crochet, M.; Penazzi, G.; Quinty, P.

    1986-01-01

    Due to their capabilities of measuring wind profiles with good time and height resolution, Stratosphere-Troposphere (ST) are well adapted to carry out atmospheric research. In France, a Very High Frequency (VHF) and an Ultrahigh Frequency (UHF) ST radar are working for research purposes. The INSU (Institut National des Sciences de l'Univers) and the DMN (Direction de la Meteorologie Nationale) networks are discussed.

  16. Modelling and Analysis Capabilities for Lightweight Masts

    DTIC Science & Technology

    2001-02-01

    Defence R&D Canada National Défense Defence nationale Modelling and Analysis Capabilities for Lightweight Masts T.S. Koko , D.P. Brennan, X. Luo, M.E...Modelling and Analysis Capabilities for Lightweight Masts T. S. Koko , D. P. Brennan, X. Luo, M. E. Norwood, L. Jiang, and U. O. Akpan... Koko The scientific or technical validity of this Contract Report is entirely the responsibility of the contractor and the contents do not necessarily

  17. Conference Proceedings on Smokeless Propellants Held in Florence, Italy on 12-13 September 1985

    DTIC Science & Technology

    1986-01-01

    September 1984) 3- D Computation Techniques Applied to Internal Flows in Propulsion Systems AGARD LS 140 (June 1985) Other Publications Airbrcathing...Technical Univcrsity 0 D T 0 Ministero della Difesa Makina Miih. 13816il’i Dirzitone Generale Costruzoni AAAS Ankara, urkey Viale declUnivcrsitýs 4,00185...Aerospace Engineering Pasadena, California 91125. US Kluyverwel; 1, 2629 HS D #elft, Netherlands M.B.Zcller Soci6t6 Nationale des Poudres ct flxplosifs

  18. Functionality and Usability Assessment of the Complement Generation Tool (CGT): A Preliminary Review (Evaluation de la Fonctionnalite et de la Convivialite de Generation de Complements (CGT) - Examen Preliminaire)

    DTIC Science & Technology

    2011-04-01

    Functionality and Usability Assessment of the Complement Generation Tool (CGT) A preliminary review Wenbi Wang...Functionality and Usability Assessment of the Complement Generation Tool (CGT) A preliminary review Wenbi Wang Defence R&D...que représentée par le ministre de la Défense nationale, 2011 DRDC Toronto TM 2011-057 i Abstract …….. The Complement Generation Tool

  19. A Portable Vital Signs Monitor For Field Use.

    DTIC Science & Technology

    1995-12-01

    casualty bag, to monitor the vital 0 signs of a person sealed therein. •9 9 iii 1.0 INTRODUCTION As early as 1973, as a consequence of Trial CHACE...environments, such as within casualty bags, without breaching the casualty’s protection. Since one of the early design criteria was to measure signs ...National DEfense Canad’i ’Defence nationale A PORTABLE VITAL SIGNS MONITOR FOR FIELD USE IDIBTRMUTION STATEUML A Apprire fmo publi me r m;~s

  20. Arctic Planning Scenarios: Scenario #2 - Safety and Security Scenario

    DTIC Science & Technology

    2011-07-01

    Narcotics are traded in bulk with cocaine & ecstasy going west and heroin going east; The US land border is now sealed behind a physical fence...nationale, 2011 Abstract …….. With the change in Northern climate over the past decade, current policy and media discussions have focused on...characterize legislation and policy on the Arctic, with a view to developing scenarios for future planning. This report presents one of two

  1. Granger Causality and National Procurement Spending: Applications to the CC130 Hercules Fleet Performance

    DTIC Science & Technology

    2011-09-01

    Assistant Deputy Minister (Materiel) DRDC CORA TM 2011-154 September 2011 Granger Causality and National Procurement Spending Applications to the CC130...Hercules Fleet Performance David W. Maybury Materiel Group Operational Research Dr aft Co py Dr aft Co py Granger Causality and National Procurement...Canada), telle que représentée par le ministre de la Défense nationale, 2011 Dr aft Co py Abstract Using Granger causality tests, we look for relationships

  2. A Random Matrix Theory Approach to National Procurement Spending: Applications to the CC130 Hercules Fleet Performance

    DTIC Science & Technology

    2010-08-01

    Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2010 Dr aft Co py Abstract We apply the methods...que l’entretien de la flotte des CC130 est robuste et que le financement n’est pas tombé sous le seuil critique qui se traduirait par des

  3. INCOMMANDS TDP: Human Factors Evaluation of the Command Decision Support Capability Prototype

    DTIC Science & Technology

    2009-03-01

    Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2009 DRDC Toronto CR 2009-041 Abstract...temps critiques . f. La CADC INCOMMANDS n’a pas d’incidence négative sur les communications qui se déroulent dans la salle des opérations. Plans

  4. Une Exception Francaise: Les Grandes Ecoles (A French Exception: The Great Schools).

    ERIC Educational Resources Information Center

    Kimmel, Alain

    1996-01-01

    Examines the role of exceptional schools in France that have produced famous personages such as Charles de Gaulle and Jean-Paul Sartre. The schools reviewed include L'Ecole Nationale d'Administration, L'Ecole Polytechnique, L'Ecole Normale Superieure, L'Ecole des Hautes Etudes Commerciales, Saint-Cyr, and L'Institut d'Etudes Politiques de Paris.…

  5. Partager : des technologies de pointe au service de la société

    ScienceCinema

    None

    2016-07-12

    Médecine, climatologie, métrologie et informatique, les techniques utilisées par le LHC trouvent déjà des répercussions dans d’autres domaines scientifiques. Utilisant des techniques inédites, la physique des particules en fait bénéficier la société toute entière.

  6. The new role of scientists

    ScienceCinema

    None

    2016-07-12

    Le D.G. Jentschke fait l'introduction et présente le Prof.Kowarsky, spécialiste en microbiologie, physique nucléaire et une des fondateurs du Cern. Il parle entre autre de l'énergie nucléaire (pacifique)et de remise en questions des valeurs scientifiques et techniques

  7. Defence SDI - A Useful Current Awareness System (Dissemination Selective de L’Information sur la Defense: Un Systeme Pratique D’Information Permanente).

    DTIC Science & Technology

    1980-09-01

    would yield: Flight characteristics, Flight clothing, Flight control , etc. Mode 3 - accepts the term only if bounded by blank spaces or punctuation. Mode...authorities. A waiting period must be expected and even then "orders" may be refused and DSIS has no control over these circumstances. The U.S. will...aux usagers accredites 5 de i’information scientifique et technique tuuchint les questions de defense, sous torme de publications r~guiieres portant sur

  8. Enhancements to DRDC Toronto’s HFE-Guide for the World-Wide-Web

    DTIC Science & Technology

    2002-07-31

    format ne comportent pas de liste cliquable de signets, de table des matieres ou d’index, ce qui reduit considerablement leur possibilite...faire des commentaires sur n’importe quel aspect du Guide, a tout moment au cours d’une seance de recherche L’autorite scientifique et les personnes...renseignements sont particulierement importants, car les articles de Ia table des matieres ne peuvent etre choisis qu’a ce niveau premier du

  9. Investigation of Solidification of High Strength Steel Castings

    DTIC Science & Technology

    1961-12-01

    2U9-259. 23. A. Kohn: "Etude de I’homogeneisation des segregations dendritiques de phosphore et ’ rsenic dans les aciers ...de la structure en bandes dans 1’ acier forge", Memoires Scientifiques de la Revue de Metallurgie, v. «j£, 6, I96I, pp. 423-^3...dans les aciers ". Revue de Metallurgie, February i960, pp. 117-134. 35. R. Castro and A. Gueussier: "La fragilite des aciers speciaux

  10. Science anc Society

    ScienceCinema

    None

    2016-07-12

    S.P.Worden, membre technique de l'U.S.délégation à Genève pour les négociations sur les armes nucléaires, est physicien, astronome, scientifique et officier de l'armée de l'air. Il parlera des technologies de défense stratégique

  11. Centenarian Einstein

    ScienceCinema

    None

    2016-07-12

    Commémoration de A.Einstein avec 4 orateurs pour honnorer sa mémoire: le prof.Weisskopf parlera de l'homme de science engagé, Daniel Amati du climat de la physique aux années 1920, Sergio Fubini de l'heure scientifique d'A.Einstein et le prof.Berob(?)

  12. A History of Full-Scale Testing of Aircraft Structures at the National Aeronautical Establishment (L’Histoire de l’Evaluation en Laboratorie de Structures d’Aeronefs a l’Etablissement Aeronautique National)

    DTIC Science & Technology

    1985-01-01

    204, Montreal Road, Ottawa, Ontario KIA 0R6 ETABLISSEMENT AERONAUTIQUE NATIONAL PUPLICATIONS SCIENTIFIQUES ET TECHNIQUES RIAPPORTS D’AERONAUTIQUE...rubber base cement . A group of patches was. o,-led bv a sinale iack through a series of links and beams known as "whiffletrees". Structural steel...was the first full-scale test in the Structures Laboratory to use electrical resistance strain gauges. These gauges, which were manufactured in the

  13. Major Events Coordinated Security Solutions: The Application of the Project Management Body of Knowledge for Managing a Science and Technology Project

    DTIC Science & Technology

    2011-02-01

    scientifiques, technologues et autres professionnels de RDDC ainsi que d’autres ministères et organismes fédéraux. La gestion de ces données aurait été...commitment to professionalism, competency and continuous learning. The Project Management Body of Knowledge (PMBOK), one of the standards established by PMI...vendor without sufficient justification. A detailed specification was developed and the requirement was competed . A total of five bids were received

  14. The Federal Public Works Infrastructure Strategy Program - Federal Works Infrastructure R&D: A New Perspective

    DTIC Science & Technology

    1993-07-01

    broader context, especially in view of the changing global environment. This more expansive view includes the traditional components and incorporates the...the Centre Scientifique et Technique du Batiment ( CSTB ), the Laboratorie Central des Ponts et Chaussees (LCPC), and the Centre Experimental de...Recherches et d’Etudes du Batiment et Travaux Publics (CEBTP). Focus of French research was defined by the CSTB in 1989, as follows: • Improvement in the

  15. International Summer School, ‘ From Genome to Life’

    PubMed Central

    2002-01-01

    This report from the International Summer School ‘From Genome to Life’, held at the Institute d'Etudes Scientifiques de Cargèse in Corsica in July 2002, covers the talks of the invited speakers. The topics of the talks can be broadly grouped into the areas of genome annotation, comparative and evolutionary genomics, functional genomics, proteomics, structural genomics, pharmacogenomics, and organelle genomes, epigenetics and RNA. PMID:18629253

  16. Geoffrey Burbidge : L'art de la critique

    NASA Astrophysics Data System (ADS)

    Bonnet-Bidaud, J. M.

    1997-06-01

    Avec pres de cinquante ans de carriere derriere lui, Geoffrey Burbidge n'a rien perdu de son gout du débat et de la controverse. Mondialement reconnu pour ses travaux sur les quasars, il en agace aujourd'hui plus d'un en venant deranger le bel ordonnancement de la cosmologie. Il porte sur le monde scientifique un regard tres critique, condamnant notamment ces chercheurs qui acceptent trop volontiers d'emprunter les chemins tout traces.

  17. Adits, Caves, Karizi-Qanats, and Tunnels in Afghanistan: An Annotated Bibliography

    DTIC Science & Technology

    2005-11-30

    Bearden, who headed up the CIA’s Soviet and Eastern European division during the 1980s, is an authority on the Soviet war in Afghanistan. Blaise ...A tentative comparison is made with deposits of lazurite in Russia north of Mongolia which are similar in petrogenesis. Blaise , Jacques, Lardeux H...tectonic maps. Map Scale: 1:2,500,000. Reference includes data from PASCAL , Institute de l’Information Scientifique et Technique, Vandoeuvre-les

  18. Colloquy to Paul Musset

    ScienceCinema

    None

    2016-07-12

    En honneur de Paul Musset il a été décidé de faire plutôt un colloque scientifique à la place d'une cérémonie. Plusieurs personnes temoignent de leurs estime et amitié pour ce physicien et ses activités

  19. Multi-Scale Autoregressive Processes

    DTIC Science & Technology

    1989-06-01

    rationnelles et leurs langages," Mas- son 1984, Collection "Etudes et Recherches en Informatique". [12] J.L. DUNAU, "Etude d’une classe de marches...June 1989 LIDS-P-1880 Multi-Scale Autoregressive Processes Michele Basseville’ Albert Benveniste’ Institut de Recherche en Informatique et Systemes...Centre National de la Recherche Scientifique (CNRS) and A.B. is also with Institut National de Recherche en Informatique et en Automatique (INRIA). The

  20. Torleif Ericson 60th Birthday

    SciTech Connect

    2008-04-09

    Plusieurs discours à l'occasion du 60me anniversaire de Torleif Ericson, physicien né à Lund (Suède), et remerciements pour son travail et son effort de relier la physique des particules à la physique nucléaire. A la fin de la cérémonie un document scientifique de 400 pages "die Festschrift" lui est remis comme cadeau d'anniversaire avec un grand nombre de contributions d'amis etc...

  1. Managerial and Organizational Determinants of Efficiency in Research Teams (Social Sciences)

    DTIC Science & Technology

    1984-05-01

    to get more funding to finance field travel and field equipment. Of course, individual teams joined this laboratory on their own will in order to...sur 1 ’ entreprise multi- nationale (CEREM) Universlt6 de Paris X, 2 rue de Rouen -92001 Nanterre CUdex P’LojeA4ew Raymond COURBIS Groupe d’analyses... financement ; 40,4 ?% uno participation fr~quente; 32,5 9o participation i tour do r~lo do tous los chorcheurs; 10,617c participation do taus los chercheurs aux

  2. Western European Nuclear Forces. A British, a French, and an American View.

    DTIC Science & Technology

    1995-01-01

    87. See also Martin S. Alexander and Philip C. F. Bankwitz, "From Politiques en Kepi to Military Technocrats: de Gaulle and the Recovery of the...1988," in Dominique David (ed.), La politique de defense de la France, Fondation pour les Etudes de Defense Nationale, Paris, 1989, p. 311. 16Pierre...d’ceuvre en peril: le consensus francais sur la defense," Esprit, March 1988, special issue, La France en politique , pp. 71-82. David S. Yost, "France

  3. Development of Paper, Chemical Agent Detector, 3-Way Liquid Containing Non-Mutagenic Dyes. 2. Replacement of the Blue Indicator Dye Ethyl-bis-(2,4- Dinitrophenyl Acetate (EDA)

    DTIC Science & Technology

    1988-06-01

    OL JU)OY (ý2ýPj 00 (V)~ Oetence nationale DTI DEVELOPIIEnT OF PAPER, CHEMICAL AGENT DETECTOR, 3-WAY LIQUID CONTAINING NON-MUTAGENIC DYES . Hi...REPLACEMENT OF THE BLUE INflICATOR DYE ETH.YL-b is-(2.4-DI NITROPH ENYL) ACETATE IEDA) by D. Thoravala, J.W. Bovenkampb, R.W. Betsa and B.V. Lcroixb...NON-MUTAGENIC DYES . n-REPLACEMENT OF THE BLUE INDICATOR DYE ETHYL-bis-(2,4-DINITROPHENYL) ACETATE (EDA) by D. Thoraval and R.W. Bets Anachemic Canada

  4. Documentation of the Carleton University Conducted Energy Weapons (CEW) Test Analysis Software (Documentation Relative au Logiciel D’analyse D’essai Elabore par L’universite Carleton pour les Armes a Impulsions (AI))

    DTIC Science & Technology

    2011-10-01

    Comité  permanent  de  la  sécurité  publique   et  nationale,  il  est  nécessaire  de  disposer  de  moyens  d’évaluation  des  armes  à  impulsions...recommendations for measurement of the performance characteristics of  conducted energy weapons. It represents the  opinions  of its authors, a group of

  5. Final closure of a low level waste disposal facility

    SciTech Connect

    Potier, J.M.

    1995-12-31

    The low-level radioactive waste disposal facility operated by the Agence Nationale pour la Gestion des Dechets Radioactifs near La Hague, France was opened in 1969 and is scheduled for final closure in 1996. The last waste package was received in June 1994. The total volume of disposed waste is approximately 525,000 m{sup 3}. The site closure consists of covering the disposal structures with a multi-layer impervious cap system to prevent rainwater from infiltrating the waste isolation system. A monitoring system has been set up to verify the compliance of infiltration rates with hydraulic performance objectives (less than 10 liters per square meter and per year).

  6. C3I for Crisis, Emergency and Consequence Management (C3I pour la gestion des crises, des urgences et de leurs consequences)

    DTIC Science & Technology

    2009-05-01

    May 2009 C3I for Crisis, Emergency and Consequence Management (C3I pour la gestion des crises , des urgences et de leurs conséquences) Research and...consequence management. ES - 2 RTO-MP-IST-086 C3I pour la gestion des crises , des urgences et de leurs conséquences (RTO-MP-IST-086...contre-terrorisme, de sécurité nationale/publique et de réponse collective face aux situations d’urgence (à la fois gestion des crises et gestion de leurs

  7. Influence of French Air Power Strategy in the European Union’s Military Operations in Africa (2003-2009)

    DTIC Science & Technology

    2011-06-01

    Prévention et Gestion des Conflits Contemporains." Défense Nationale et Sécurité Collective June 2007, 35-43. Knutsen, Bjørn Olav. "The EU and the...2 Francois Gaulme, "La Politique Française d’ Intervention Dans les Conflits Limités en Afrique" (paper presented at the The Use of Air Power in...Française d’Intervention Dans les Conflits Limités en Afrique", 7. 4 Gaulme, "La Politique Française d’Intervention Dans les Conflits Limités en Afrique

  8. LL and E awarded E and D contract area in eastern Algeria

    SciTech Connect

    Not Available

    1992-12-07

    This paper reports that a Louisiana Land and Exploration Co. unit has been awarded on exploration and production contract in Algeria by state oil company Enterprise Nationale Sonatrach. LL and E Algeria Ltd.'s contract covers two blocks in the central Ghadames oil basin of eastern Algeria. LL and E said the contract, yet to be submitted for government approval, calls for a minimum investment of $33 million during a 5 year work program that includes seismic acquisition and drilling a minimum of three wildcats.

  9. Assessing the Effects of Crew Exposure to Cabin Altitudes of 8,000 ft to 10,000 ft. A Literature Review and Recommendations

    DTIC Science & Technology

    2002-08-01

    the Minister of National Defence, 2002 "© Sa majestd la reine, repr~sent6e par le ministre de la Defense nationale, 2002 - - - , m m6 Abstract...d’altitude reposent sur une r~duction de Pactivit6 du syst~me sympathique au moyen d’un traitement A la clonidine ou au propranolol (deux m ~dicaments utilis~s...the full duration of such a mission. Paul, M ., Gray, G. 2002. Assessing the effects of crew exposure to cabin altitudes of 8,000 ft to 10,000 ft: A

  10. Prospect for the formation of a gas of ultracold polar NaRb molecules

    NASA Astrophysics Data System (ADS)

    Quéméner, Goulven; Vexiau, Romain; Wang, Gaoren; Lepers, Maxence; Luc, Eliane; Bouloufa-Maafa, Nadia; Dulieu, Olivier; Wang, Dajun

    2015-05-01

    We present a complete theoretical model for the formation of an ultracold gas of polar NaRb molecules, based on high-precision spectroscopic data completed with accurate quantum chemistry calculations. Weakly-bound molecules are first created via a Feshbach resonance with main triplet character. The population is transfered down to the lowest rovibrational level of the ground state by a coherent STIRAP process. The efficiency of various paths via different electronically-excited molecular states is discussed in relation of the ongoing experimental implementation. Supported by Agence Nationale de la Recherche (ANR), project COPOMOL (# ANR-13-IS04-0004-01).

  11. Hydrogeological Investigations in Deep Wells at the Meuse/Haute Marne Underground Research Laboratory

    NASA Astrophysics Data System (ADS)

    Delay, Jacques; Distinguin, Marc

    ANDRA (Agence Nationale pour la Gestion de Déchets Radioactifs) has developed an integrated approach to characterizing the hydrogeology of the carbonate strata that encase the Callovo-Oxfordian argillite at the Meuse/Haute-Marne Laboratory site. The argillites are difficult to characterize due to their low permeability. The barrier properties of the argillites can be inferred from the flow and chemistry properties of the encasing Oxfordian and Dogger carbonates. Andras deep hole approach uses reverse air circulation drilling, geophysical logging, flow meter logging, geochemical sampling, and analyses of the pumping responses during sampling. The data support numerical simulations that evaluate the argillites hydraulic behaviour.

  12. National Program for Inspection of Non-Federal Dams. Mill Pond Dam (MA 00161) Danvers River Basin, Danvers, Massachusetts. Phase I Inspection Report.

    DTIC Science & Technology

    1980-12-01

    receiving a flash flood warning, either from the NationalL Weather Service or the Town’s pri- vate weather service, the Town re- moves flashboards to lower...which is about 1 to 1.5 ft. higher than normally maintained during late fall, winter and spring months or at times when flash flood warnings are...following conditions: a. Upon receiving a flash flood warning, either from the National Weather Service or the Town’s pri- vate weather service, the

  13. British and French Strategic Nuclear Force Modernization: Programs, Strategies, and Implications

    DTIC Science & Technology

    1989-12-01

    SSBN availability due to an unforeseen emergency (e.g., an accident , or significant delay to SSBN 05 or 06 [Van-guard or Victorious]; or a loss of a...EEC and defence split," Tb Guardian, 30 January 1988. 17. "Le gouvernement britannique n’a pas renonce a un missile nucleaire commun avec ]a France...67. Chirac, Jacques, "Au sujet des armes nucleaires tactiques frangaises," Defense Nationale, May 1975, as cited in Ref. 20:p. 151. 68. Hernu, Charles

  14. Resolving Ethical Dilemmas: Exploring the Role of Moral Principles

    DTIC Science & Technology

    2008-08-01

    fondations des codes d’honneur et de conduite professionnelle et serviraient aussi de base pour les lois qui sont au cœur du travail des militaires... professionnels , qu’il soit question de droit international ou de droit des conflits armés par exemple. Dans un contexte militaire également, les principes...étaient tous les professionnels associés au ministère canadien de la Défense nationale alors que notre échantillonnage était formé d’un ensemble

  15. Layered Protocol Analysis of a Control Display Unit

    DTIC Science & Technology

    1997-12-01

    National DW ense C n dI iDefence nationale ai LAYERED PROTOCOL ANALYSIS OF A CONTROL DISPLAY UNIT Defence and Civil INSTITUTE OF ENVIRONMENTAL...Primary node and strong disbelief (red) to the End node and 0 strong belief (blue). LEGEND first recursion second recursion third recursion O( x ) O(R( x )) O...R(O( x ))) 0 PI P2 P3 Feedback Forms * ~Srong Belief U Null I weak belief INeutral______ *InformR no opinion NODE 0 weak disbelief Strong Disbelief one

  16. Frequency and Amplitude Characteristics of a High-Repetition-Rate Hybrid TEA-CO2 Laser,

    DTIC Science & Technology

    1978-02-01

    RA—ETC(U) FEB 78 J - LACNAMBRE» P LAVIGNE. M VERREAULT DREV-R-«»091/78 NL | OF | A05I853 4-78 Uftt I.I IM 12.5 i- m 12.2 I US 12.0...L. Lachambre P. Lavigne M. Verreault G. Otis Po ^e O OS«l BUREAU - RECHERCHE ET OEVEIOPPEMENT MINISTER« DE IA DEFENSE NATIONALE CANADA...JSEPETITION-RATE , HYBRID T£A.-C£? L.ASER . / J.-L./Lachambre, p/Lavigne, M./ Verreault ^jBi G./°tis *Gen-Tec Inc., Quebec (S2E57 <^s Quebec

  17. Adding a Capability to Extract Sentiment from Text Using HanDles

    DTIC Science & Technology

    2012-05-01

    Minister of National Defence, 2012 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2012...HanDles afin qu’il fasse la distinction entre bonnes et mauvaises critiques de film. Nous avons exécuté ce scénario à trois reprises dans le but de...vérifier à quel point il parvient à classifier correctement les documents. Le premier essai portait sur des critiques de l’appareil Kindle d’Amazon

  18. Trust Violation and Repair (12oe): Project Summary and Closeout Report

    DTIC Science & Technology

    2008-09-01

    Minister of National Defence, 2008 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2008 DRDC...subject matter expert (SME) feedback and critique was elicited. This feedback occurred in five focus groups with 19 Canadian Forces (CF) personnel who...confiance de manière à refléter les dimensions théoriques importantes de la confiance, puis l’on a cherché à obtenir la rétroaction et les critiques

  19. The 2007 Surge in Iraq: An Alternative View

    DTIC Science & Technology

    2014-11-01

    la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2014 DRDC-RDDC-2014-R105 i Abstract...milices aurait eu pour effet de repousser de plusieurs mois un nouveau sommet de violence. Dans notre étude, nous faisons un examen critique d’autres...pour effet de repousser de plusieurs mois un nouveau sommet de violence. Dans notre étude, nous faisons un examen critique d’autres facteurs qui

  20. Internet Based Robot Control Using CORBA Based Communications

    DTIC Science & Technology

    2009-12-01

    the Minister of National Defence, 2009 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale...interact with a service. Its lack of tools to support implementation is the main critique against it. 3.6.2 WSDL-based Web Services This type of Web...The main critiques against it are its complexity and loss of functionality of the “back” button and bookmarking ability for web browsers, though the

  1. EGS Richardson AGU Chapman NVAG3 Conference: Nonlinear Variability in Geophysics: scaling and multifractal processes

    NASA Astrophysics Data System (ADS)

    Schertzer, D.; Lovejoy, S.

    was followed by five days with 8 oral sessions and one poster session. Overall, there were 65 papers involving 74 authors. In general, the main topics covered are reflected in this special issue: geophysical turbulence, clouds and climate, hydrology and solid earth geophysics. In addition to AGU and EGS, the conference was supported by the International Science Foundation, the Centre Nationale de Recherche Scientifique, Meteo-France, the Department of Energy (US), the Commission of European Communities (DG XII), the Comite National Francais pour le Programme Hydrologique International, the Ministere de l'Enseignement Superieur et de la Recherche (France). We thank P. Hubert, Y. Kagan, Ph. Ladoy, A. Lazarev, S.S. Moiseev, R. Pierrehumbert, F. Schmitt and Y. Tessier, for help with the organization of the conference. However special thanks goes to A. Richter and the EGS office, B. Weaver and the AGU without whom this would have been impossible. We also thank the Institut d' Etudes Scientifiques de Cargese whose beautiful site was much appreciated, as well as the Bar des Amis whose ambiance stimulated so many discussions. 2. Tribute to L.F. Richardson With NVAG3, the European geophysical community paid tribute to Lewis Fry Richardson (1881-1953) on the 40th anniversary of his death. Richardson was one of the founding fathers of the idea of scaling and fractality, and his life reflects the European geophysical community and its history in many ways. Although many of Richardson's numerous, outstanding scientific contributions to geophysics have been recognized, perhaps his main contribution concerning the importance of scaling and cascades has still not received the attention it deserves. Richardson was the first not only to suggest numerical integration of the equations of motion of the atmosphere, but also to attempt to do so by hand, during the First World War. This work, as well as a presentation of a broad vision of future developments in the field, appeared in his

  2. Engaging the Public to Identify Opportunities to Improve Critical Care: A Qualitative Analysis of an Open Community Forum

    PubMed Central

    Potestio, Melissa L.; Boyd, Jamie M.; Bagshaw, Sean M.; Heyland, Daren; Oxland, Peter; Doig, Christopher J.; Zygun, Dave; Stelfox, Henry T.

    2015-01-01

    Objective To engage the public to understand how to improve the care of critically ill patients. Design A qualitative content analysis of an open community forum (Café Scientifique). Setting Public venue in Calgary, Alberta, Canada. Participants Members of the general public including patients, families of patients, health care providers, and members of the community at large. Methods A panel of researchers, decision-makers, and a family member led a Café Scientifique, an informal dialogue between the populace and experts, over three-hours to engage the public to understand how to improve the care of critically ill patients. Conventional qualitative content analysis was used to analyze the data. The inductive analysis occurred in three phases: coding, categorizing, and developing themes. Results Thirty-eight members of the public (former ICU patients, family members of patients, providers, community members) attended. Participants focused the discussion and provided concrete suggestions for improvement around communication (family as surrogate voice, timing of conversations, decision tools) and provider well-being and engagement, as opposed to medical interventions in critical care. Conclusions Café participants believe patient and family centered care is important to ensure high-quality care in the ICU. A Café Scientifique is a valuable forum to engage the public to contribute to priority setting areas for research in critical care, as well as a platform to share lived experience. Research stakeholders including health care organizations, governments, and funding organizations should provide more opportunities for the public to engage in meaningful conversations about how to best improve healthcare. PMID:26580406

  3. Préface

    NASA Astrophysics Data System (ADS)

    Paulus, Werner; Meinnel, Jean

    2003-02-01

    En 1994, l'attribution du prix Nobel à Cliff Shull et Bert Brockhouse pour leurs travaux de pionniers pendant les années 50, concernant tant la diffusion élastique des neutrons que la diffusion inélastique, a été la reconnaissance éclatante de l'importance de la diffusion neutronique pour toute la communauté scientifique.Le grand intérêt du neutron pour la recherche s'appuie principalement sur ses propriétés physiques particulières :- les neutrons utilisés pour la caractérisation de la matière (et fournis en relativement grandes quantités par les réacteurs ou les sources à spallation) disposent de longueurs d'onde et d'énergies correspondant directement aux distances interatomiques et aux énergies d'agitation de la matière. Ainsi, par diffusion neutronique, on peut étudier en même temps la structure et le comportement dynamique de la matière ;- le fait que le neutron soit doué d'un moment magnétique lui permet d'interagir avec tout atome porteur d'un moment magnétique. Ceci permet de caractériser intimement le comportement magnétique de la matière à l'échelle microscopique ;- la possibilité de pouvoir varier facilement le contraste d'un même élément en utilisant ses différents isotopes fait du neutron un outil irremplaçable en chimie et physique du solide ainsi qu'en biologie et matière molle ;- enfin, n'ayant pas de charge électrique, les neutrons peuvent pénétrer la matière sans être absorbés significativement, ce qui rend possible une caractérisation non destructive des contraintes et textures sur de grosses pièces des matériaux.Toutes les qualités des neutrons mentionnées ci-dessus permettent de comprendre l'importance de la diffusion neutronique pour des domaines très nombreux et très différents à la fois en recherche fondamentale mais aussi pour des applications industrielles. L'utilisation de l'outil-neutron demande toutefois non seulement une bonne connaissance des différents mécanismes d

  4. Calendar of Selected Aeronautical & Space Meetings, January 1990 (Calendrier des Manifestations Aeronautiques et Spatiales (Selection) Janvier 1990

    DTIC Science & Technology

    1990-01-01

    scientifique et technique; " En leur 6vitant l’obligation de consulter diff~rentes sources pour ddter- miner les reunions qui ont 6t programm ~es...Ch. 1). (Veuillez noter que les manifestations dont le programme couvre plusieurs themes parmi ceux: qui sont indiqu~s ci-dessus de 0 1 09, sont...und Raunifahrt : Postfach 3267, D-3300 Braunschweig GE DGLR Deutsche Geselischaft rur Luft-und-Raunifalirt: Godesberger Allee 70, D-5 300 Bonn 2 GE DLR

  5. Advantage of collocating research facilities The administrator's point of view

    NASA Astrophysics Data System (ADS)

    Spilker, H.-M.; Blomeyer, C.

    1995-02-01

    Research facilities are collocated in order to create a maximum of synergy. This also requires a close cooperation of the administration concerned leading to advantages, in particular with regards to infrastructure and cost effectiveness. Faced with the specificities of the research facilities involved, administrators feel challenged to find appropriate solutions. The successive establishment of research institutes on the Polygone Scientifique in Grenoble is described. Forms and content of administrative collaboration between the Institut Max von Laue-Paul Langevin and the European Synchrotron Radiation Facility are analysed, where collocation has led to intensive cooperation.

  6. Towards a General-Purpose Belief Maintenance System.

    DTIC Science & Technology

    1987-04-01

    cardinalitylconjunctsi). OR Both ’Garvey et A. 1981) and lRodewaid, 1984) nefine he belief :n OR -o 3e rhe maximum oi the individuai beliefs: B. 1 ’W iA v B...Scientifique .t Tecnnique Knowledge Systems Laboratory CNRS 701 Welch Road, Bldg. C IS Qua Anatoe F-ance Dr Fred Chang Pato Alto, CA 94304 75700 Paris FRANCE...hura iA 2204.2 icnooi .f Education Staniorl fanversitv Staniori CA 94305 u Distribution List [Illinois/Gentner] NR 667-551 Dr. Barbel Inhelder Dr

  7. Vagabonds de l'espace

    NASA Astrophysics Data System (ADS)

    Lang, Kenneth R.; Whitney, Charles A.; Heidmann, J.; Heidmann, M.-A.

    Les astronomes Lang et Whitney pr sentent ici sur notre syst me plan taire un livre compr hensible pour tous sans demander de connaissances pr alable en la mati re. L'ouvrage, o alternent judicieusement une criture limpide et de nombreuses photographies en partie in dites, traite une quantit poustouflante de connaissances scientifiques, tenant compte des r sultats fournis par les toute derni res missions de sondes spatiales et de satellites (1992). R f rences historiques, tableaux et bibliographie d taill e viennent le compl ter pour en faire un ouvrage qui s'adresse aussi tout fait l'astronome amateur actif. '

  8. Technical Description of Urban Microscale Modeling System: Component 1 of CRTI Project 02-0093RD

    DTIC Science & Technology

    2007-03-01

    de la dispersion concomitante des mati res lib6r6es dans ces courants est tr6s importante. Les modMles de pr6diction des courants ur- bains et de...Suffield TR 2007-067 Res u m e Ce rapport fournit une description technique des mod6les compris dans la Cornposante I d’un projet de 4 ans appel6 Initiative...principal de ce projet consiste h d6vel- opper un systbme de mod6lisation, h la pointe de la recherche scientifique et totalement valid6, de pr6diction du

  9. Modelling the Sea King Helicopter in the Integrated Performance Modelling Environment (IPME)

    DTIC Science & Technology

    2004-03-01

    scientifique (AS), des experts de Humansystems en matikre d’IPME et de facteurs humains ainsi que des experts en la mati ~ re (EM) de TopAces ayant une certaine...nmoddle de performance humaine pour les activit&s des pilotes li~es A l’hdlicopt& re Sea King. Plus particulikrement, RDDC Toronto voulait que le moddle de...moddle servirait A contr6ler un h6licopt& re Sea King simul6. L’application de mod6lisation de la performance humaine utilis6e pour ce projet 6tait

  10. Mathematical Models of Gas Turbine Engines and Their Components (Les Modeles Mathematiques des Turbomoteurs et de leurs organes)

    DTIC Science & Technology

    1994-12-01

    Cooperation Programme. Abrege Ce cycle de conferences presente et expose les problemes scientifiques poses par les modeles mathematiques des turbomoteurs et...matrix M Mach number Re Reynolds number Pr Prandtl number T temperature U conservative variables k turbulent kinetic energy P pressure t time V...pvr P% e G = G,-GV, (i.i) E = E,-EU F: PVr PVxVr pv"+p PVr% (e + p)vr E,= PVx pvl+P PVxV<, (e + p)vx P% P^% 9VrVV Re G- = RS Ap

  11. Application of the Semantics Enrichment Concept in the Information Fusion for Command Support

    DTIC Science & Technology

    2006-12-01

    pour le commandement - La réponse MATIS - in Revue scientifique et technique de la Défense - n°25. Juin 1994. Renouard F., Rossazza J.P. - Fasade : un...that A’(β) ⊂ A (β). In the observation space of a perceptual system will only be re -found the fragments of OB noted : O(β), for reasons mentioned...applied in a research project : MATIS . ∆ Φ Ω α 0.1 0.2 0 M(RAxB) x M(RBxC) = β 0.2 0 0 γ 0.1 0.2 0.3 Application of the

  12. Command and Control Workshop: Structures and Processes for R&D Service Delivery

    DTIC Science & Technology

    1996-12-01

    le commandement et controle du 7 au 9 mai 1996 dont le but etait de reunir scientifiques du CRDev et o:fficiers des Forces canadiennes pour discuter...des besoins et des moyens en matiere de R&D pour le commandement et controle. Regroupes en deux ateliers, les participants firent appel a une...cannot keep up. The idea of"proto-cycling" may be adaptable to this e nvironment. The syndicates had 29 ideas of how this might be established. The

  13. Memorial V.J.Glaser

    ScienceCinema

    None

    2016-07-12

    Plusieurs orateurs rendent hommage au grand physicien et scientifique Vladimir Jurko Glaser (1924 - 1984) qui travaillait au Ruder Boscovic Institut à Zagreb avant de venir au Cern en 1957 où il trouvait un poste permanent au département de physique théorique. Walter Tearing, Harry Lehmann,Henry Epstein, Jacques Bros et André Martin font des résumés biographiques de leurs collègue et ami en honorant ses grands qualités d'homme et ses remarquables conquêtes de la science et leurs accomplissement.

  14. Toxoplasmose oculaire atypique chez une femme congolaise de 72 ans: à propos d'une observation

    PubMed Central

    Bienvenu, Yogolelo Asani; Angel, Musau Nkola; Eric, Kasamba Ilunga; Socrate, Kapalu Mwangala; Sebastien, Mbuyi Musanzayi; Philippe, Cilundika Mulenga; Leon, Kabamba Ngombe; Bruno, Iye Ombamba Kayimba; Gaby, Chenge Borasisi

    2015-01-01

    Les auteurs rapportent un cas de toxoplasmose oculaire binoculaire, rarement décrit dans la littérature, chez une personne âgée de 72 ans, de sexe féminin, à laquelle s'associe une rétinite pigmentaire unilatérale. Cette observation permet d'attirer l'attention de la communauté scientifique sur les autres formes ou variétés de présentation moins courantes, « atypiques », pouvant être rencontrées ou associées à la toxoplasmose oculaire. PMID:26958130

  15. Maritime Electromagnetism and DRDC Signature Management Research

    DTIC Science & Technology

    2005-12-01

    characteristics of naturally occurring electromagnetism i.e. ambient electromag- netic fields in the oceans are described. In particular, the sources or...physical processes generating the fields, their magnitudes and the relevant time scales are noted. The ambient fields include the Earth’s geomagnetic...Résumé On examine de façon sélective le vaste domaine de l’électromagnétisme en milieu marin du point de vue de la gestion scientifique des signatures

  16. What would researchers like to improve in communication initiatives?

    NASA Astrophysics Data System (ADS)

    Russo, Pedro

    2015-08-01

    One of the most important current trends in astronomy communication has been “change”. The field of astronomy communication has rapidly evolved in just the past few years, as new techniques and technologies have been adopted. Research astronomy has also visibly changed, as automation of survey systems and the launch of new telescopes has produced a tsunami of big data sets. Today, scientists and communicators must work together to navigate the raging waters of this data flood as they strive to keep our tech-savvy society informed. This invited talk will be given by Alain Doressoundiram (Observatoire de Paris, Centre National de la Recherche Scientifique, France) TBC

  17. Planetes, etoiles, galaxies, trous noirs : comment peser l'Univers ?

    NASA Astrophysics Data System (ADS)

    Bonnet-Bidaud, J. M.

    2001-05-01

    Depuis plus de trois siècles, les astronomes affinent leurs méthodes pour `peser' à distance les astres qui peuplent l'Univers. Après avoir décortiqué les orbites, étudié les décalages vers le rouge, épluché la luminosité, les scientifiques ont ajouté les lentilles gravitationnelles à la liste de leurs `balances' cosmiques. Outils et moyens de ceux qui évaluent la masse des objets célestes.

  18. Exceptional supergravity theories and the magic square

    NASA Astrophysics Data System (ADS)

    Günaydin, M.; Sierra, G.; Townsend, P. K.

    1983-12-01

    We derive the magic square of Freudenthal, Rozenfeld, and Tits from the geometry of a special class of N=2 Maxwell-Einstein supergravity theories. We also show that all of these theories are obtainable by truncation of N=8 supergravity theories in various spacetime dimensions d, except for an ``exceptional'' subclass, unique for a given d, which is associated with with the exceptional Jordan algebra of 3 × 3 hermitian octonionic matrices. Laboratoire Propre du Centre National de la Recherche Scientifique, associé à l'Ecole Normale Supérieure et à l'Université de Paris-Sud.

  19. Foreword

    NASA Astrophysics Data System (ADS)

    Priou, Alain; Lupi, Cyril

    2016-11-01

    URSI (;Union radio-scientifique internationale;) is a world-level body under the umbrella of the International Council for Science, formerly International Council of Scientific Unions (ICSU). This scientific society is responsible for stimulating and coordinating, on an international basis, studies, research, applications, scientific exchanges, and communication in the fields of radio science. In 2015, the yearly scientific workshop of URSI-France was focused on the theme ;Probing matter with electromagnetic waves;. This research area covers all the activities of the various scientific commissions of URSI.

  20. [SIGAPS: a software package for the evaluation of medical publications].

    PubMed

    Derancourt, C; Devos, P; Moore, N; Rouvillain, J-L

    2014-01-01

    The "système d'interrogation, de gestion et d'analyse des publications scientifiques" (System for Identification, Management and Analysis of Scientific Publications), or SIGAPS, is an innovative tool of French design that enables the identification and analysis of bibliographic references produced by a given researcher or unit using the Medline database (PubMed). This evaluation takes into account the author's rank of signature and the impact factor of the journal of publication within the discipline in question. The limits are those of the impact factor. Analyses produced by SIGAPS enable financial assessment to be made by hospitals.

  1. Identification of complex flows in Taylor-Couette counter-rotating cavities

    NASA Technical Reports Server (NTRS)

    Czarny, O.; Serre, E.; Bontoux, P.; Lueptow, R. M.

    2001-01-01

    The transition in confined rotating flows is a topical problem with many industrial and fundamental applications. The purpose of this study is to investigate the Taylor-Couette flow in a finite-length cavity with counter-rotating walls, for two aspect ratios L=5 or L=6. Two complex regimes of wavy vortex and spirals are emphasized for the first time via direct numerical simulation, by using a three-dimensional spectral method. The spatio-temporal behavior of the solutions is analyzed and compared to the few data actually available. c2001 Academie des sciences/Editions scientifiques et medicales Elsevier SAS.

  2. Chemistry at Clusters, Microstructures and Surfaces

    DTIC Science & Technology

    1989-12-01

    Advances in Laser Sciences - II, ed. by M. Lapp. W. C. Stwallev and G. A. Kenney-Wallace, AIP Conf. Proc. 160, 49 3 -D (1987). 17. A. Peremans, J. Darville ...Vol. 1 (Fonds National de la Recherche Scientifique, Brussels, Belgium, 1986), pp. 67-9. 4. A. Peremans, J. Darville , J.-M. Gilles and T. F. George...Limit," Bull. Am. Phys. Soc. 32, 910 (1987). 10. A. Peremans, J. Darville , J.-M. Gilles and T. F. George, "Infrared Laser- Stimulated Catalysis. Theory

  3. Torleif Ericson 60th Birthday

    ScienceCinema

    None

    2016-07-12

    Plusieurs discours à l'occasion du 60me anniversaire de Torleif Ericson, physicien né à Lund (Suède), et remerciements pour son travail et son effort de relier la physique des particules à la physique nucléaire. A la fin de la cérémonie un document scientifique de 400 pages "die Festschrift" lui est remis comme cadeau d'anniversaire avec un grand nombre de contributions d'amis etc...

  4. Seminar Andrej Sacharov

    SciTech Connect

    2006-08-23

    A l'occasion de son 63me anniversaire 2 orateurs rendent hommage à A.Sacharov, physicien russe et né à Moscou, pour ses accomplissements scientifiques et son courage. A.Sacharov a dénoncé les dangers de la radioactivité et a tenté de persuader les autorités soviétiques de supprimer une série de test après le developpement de la bombe atomique en 1949 et la bombe à hydrogène en 1953 par un groupe de chercheurs soviétiques. Il a obtenu le prix Nobel en 1975.

  5. Assessment Methods for Personal Active Noise Reduction Validated in an International Round Robin (Methodes d’evaluation des protecteurs auditifs a attenuation active du bruit)

    DTIC Science & Technology

    2004-08-01

    peuvent aussi se comporter de façon non linéaire aux niveaux élevés. De ce fait, les méthodes d’évaluation standard (méthode subjective de mesure des... programmes Ear protectors Helicopters Helmets Human factors engineering Military aircraft Noise (sound) Noise reduction Protective equipment...Virginia 2216 STAR est édité par CASI dans le cadre du programme ETATS-UNIS NASA d’information scientifique et technique (STI) (accessible également

  6. Pierre Ambroise-Thomas: a loyal friend and a strong supporter of tropical medicine in Brazil.

    PubMed

    Daniel-Ribeiro, Cláudio Tadeu

    2016-01-01

    Our colleagues at the Sociedade Brasileira de Medicina Tropical have been informed of the demise of Professor Pierre Ambroise-Thomas (1937-2014). However, considering that the tribute we paid to him in 2015 - at the 20th anniversary of the Seminário Laveran & Deane sobre Malária - is equally true today, it is worth sharing it with the readers of the RSBMT, in recognition of his many virtues. Pierre Ambroise-Thomas (MD in 1963 and DSc in 1969) was Honorary Professor of Parasitology and Tropical Medicine at the Faculté de Médecine de Grenoble (France), Honorary President of the Académie Nationale de Médecine, member of the Académie Nationale de Pharmacie and Officier dans l'Ordre de La Légion d'Honneur. In addition to his important contributions to tropical medicine and parasitology, working in France during his long and productive career (50 years and 300 publications), Ambroise-Thomas became an admirer and supporter of Brazilian activities related to research, teaching and information in Tropical Medicine.

  7. La supraconductivité a 100 ans !

    SciTech Connect

    2011-04-14

    Il y a 100 ans, le 8 avril 1911, une découverte majeure était réalisée : celle de la supraconductivité. La supraconductivité est la caractéristique qu’ont certains métaux et alliages de perdre toute résistance électrique en dessous d’une température donnée. Cette renversante découverte, réalisée de manière presque fortuite par Kammerlingh Onnes de l’Université de Leyde (Pays-Bas) et son étudiant Gilles Holst, a ouvert un nouveau champ de recherche en physique et de fabuleuses perspectives d’applications technologiques. Du point de vue scientifique, la supraconductivité est en effet l’une des rares manifestations de la physique quantique à l’échelle macroscopique.  Du point de vue des retombées techniques, elle est porteuse d’applications majeures dans le domaine de la santé, des communications et de l’énergie. 100 ans après, les physiciens n’ont toujours pas fini d’explorer ce phénomène et ses applications. Le CERN abrite des applications de la supraconductivité à des échelles inédites. L’accélérateur de particules LHC, avec ses milliers d’aimants supraconducteurs répartis sur 27 kilomètres de circonférence, est en effet la plus grande application mondiale de la supraconductivité. Il ne pourrait exister sans elle.  Le CERN fête donc la découverte de la supraconductivité avec une conférence exceptionnelle donnée par Philippe Lebrun. Au cours de cette conférence, l’expérience historique de Kammerlingh Onnes sera reproduite. Philippe Lebrun racontera l’histoire de cette étonnante découverte, en la replaçant dans le contexte scientifique de l’époque. Il racontera les développements scientifiques et les applications du premier siècle de la supraconductivité. Conférence en français Merci de bien vouloir vous inscrire au : +41 22 767 76 76 ou cern.reception@cern.ch

  8. Le recours aux modeles dans l'enseignement de la biologie au secondaire : Conceptions d'enseignantes et d'enseignants et modes d'utilisation

    NASA Astrophysics Data System (ADS)

    Varlet, Madeleine

    Le recours aux modeles et a la modelisation est mentionne dans la documentation scientifique comme un moyen de favoriser la mise en oeuvre de pratiques d'enseignement-apprentissage constructivistes pour pallier les difficultes d'apprentissage en sciences. L'etude prealable du rapport des enseignantes et des enseignants aux modeles et a la modelisation est alors pertinente pour comprendre leurs pratiques d'enseignement et identifier des elements dont la prise en compte dans les formations initiale et disciplinaire peut contribuer au developpement d'un enseignement constructiviste des sciences. Plusieurs recherches ont porte sur ces conceptions sans faire de distinction selon les matieres enseignees, telles la physique, la chimie ou la biologie, alors que les modeles ne sont pas forcement utilises ou compris de la meme maniere dans ces differentes disciplines. Notre recherche s'est interessee aux conceptions d'enseignantes et d'enseignants de biologie au secondaire au sujet des modeles scientifiques, de quelques formes de representations de ces modeles ainsi que de leurs modes d'utilisation en classe. Les resultats, que nous avons obtenus au moyen d'une serie d'entrevues semi-dirigees, indiquent que globalement leurs conceptions au sujet des modeles sont compatibles avec celle scientifiquement admise, mais varient quant aux formes de representations des modeles. L'examen de ces conceptions temoigne d'une connaissance limitee des modeles et variable selon la matiere enseignee. Le niveau d'etudes, la formation prealable, l'experience en enseignement et un possible cloisonnement des matieres pourraient expliquer les differentes conceptions identifiees. En outre, des difficultes temporelles, conceptuelles et techniques peuvent freiner leurs tentatives de modelisation avec les eleves. Toutefois, nos resultats accreditent l'hypothese que les conceptions des enseignantes et des enseignants eux-memes au sujet des modeles, de leurs formes de representation et de leur approche

  9. The Nagra-DOE Cooperative Project

    SciTech Connect

    Long, J.C.S.; Levitch, R.A.; Zuidema, P.

    1993-04-01

    The Nagra-DOE Cooperative (NDC-I) research program was sponsored by the US Department of Energy (DOE) through the Lawrence Berkeley Laboratory (LBL), and the Swiss Nationale Genossenschaft fuer die Lagerung radioaktiver Abfaella (Nagra). Scientists participating in this project explored the geological, geophysical, hydrological, geochemical, and structural effects anticipated from the use of a rock mass as a geologic repository for nuclear waste. Six joint tasks were defined and are described briefly below. Tasks 1, 2, 3 and 5 were concerned with the characterization of fractured rock. Task 5 in particular was focused on investigations at the Grimsel Underground Laboratory in the Swiss Alps. Tasks 2 and 6 focused on the phenomenology associated with storing radioactive waste underground.

  10. How was the UNAIDS drug access initiative implemented in Chile?

    PubMed

    Brousselle, Astrid; Champagne, François

    2004-01-01

    In 1997, UNAIDS decided to implement Drug Access Initiatives (DAI) in four different pilot-countries. We studied the implementation of the DAI in Chile as part of the evaluation program conducted by the 'Agence Nationale de Recherche sur le SIDA' (ANRS/France). The objective was to understand how the politico-organizational dynamic influenced the implementation process of the DAI. Approximately 50 semi-directed interviews and observation activities were conducted with the actors who participated in the implementation of the DAI or who played a role in the HIV/AIDS context. The program theory models were established and their evolution analyzed. This article offers an original analysis of an international HIV/AIDS drug access program that was put in place at a time when such programs were seen as a priority by international and governmental institutions. It also offers some insights for the creation of international projects that will be locally implemented.

  11. Spontaneous actin dynamics in contractile rings

    NASA Astrophysics Data System (ADS)

    Kruse, Karsten; Wollrab, Viktoria; Thiagarajan, Raghavan; Wald, Anne; Riveline, Daniel

    Networks of polymerizing actin filaments are known to be capable to self-organize into a variety of structures. For example, spontaneous actin polymerization waves have been observed in living cells in a number of circumstances, notably, in crawling neutrophils and slime molds. During later stages of cell division, they can also spontaneously form a contractile ring that will eventually cleave the cell into two daughter cells. We present a framework for describing networks of polymerizing actin filaments, where assembly is regulated by various proteins. It can also include the effects of molecular motors. We show that the molecular processes driven by these proteins can generate various structures that have been observed in contractile rings of fission yeast and mammalian cells. We discuss a possible functional role of each of these patterns. The work was supported by Agence Nationale de la Recherche, France, (ANR-10-LABX-0030-INRT) and by Deutsche Forschungsgemeinschaft through SFB1027.

  12. Role of Van der Waals interactions in determining the structure of liquid tellurides

    NASA Astrophysics Data System (ADS)

    Micoulaut, Matthieu; Flores-Ruiz, Hugo; Coulet, Vanessa; Piarristeguy, Andrea; Johnson, Mark; Cuello, Gabriel; Pradel, Annie

    The simulation of tellurides using standard density functional (DFT) theory based molecular dynamics usually leads to an overestimation of the bond distances and a noticeable mismatch between theory and experiments when e.g. structure functions are being directly compared. Here, the structural properties of several compositions of Ge-Te and Ge-Sb-Te liquids are studied from a combination of neutron diffraction and DFT-based molecular dynamics. Importantly, we find an excellent agreement in the reproduction of the structure in real and reciprocal spaces, resulting from the incorporation of dispersion forces in the simulation. We then investigate structural properties including structure factors, pair distribution functions, angular distributions, coordination numbers, neighbor distributions, and compare our results with experimental findings. References:Physical Review B 92, 134205 (2015)Physical Review B 89, 174205 (2014)Physical Review B 90, 094207 (2014) Support from Agence Nationale de la Recherche (ANR) (Grant No. ANR-11-BS08-0012) is gratefully acknowledged.

  13. Ultracold two-body dynamics in optical lattices with topological singularities

    NASA Astrophysics Data System (ADS)

    Aghamalyan, Davit; Simoni, Andrea; Launay, Jean-Michel

    2016-05-01

    We study bound levels of two particles trapped in a 2D optical lattice. We use a short-range potential tuned to reproduce typical experimental conditions. Near-threshold bound states are computed using a spectral element discretization approach that guarantees exponential precision in the numerical results. High computational efficiency is attained due to the very sparse nature of the Hamiltonian in this representation. The calculated wavefunction is analyzed both in real and in momentum space. We perform calculations both for standard separable optical potentials and for lattice with topological singularities (Dirac cones) in the band structure. Extension to the calculation of scattering states will be addressed. This work was supported by the Agence Nationale de la Recherche (Contract No. ANR-12-BS04-0020-01).

  14. Molecular spectroscopy for producing ultracold ground-state NaRb molecules

    NASA Astrophysics Data System (ADS)

    Wang, Dajun; Guo, Mingyang; Zhu, Bing; Lu, Bo; Ye, Xin; Wang, Fudong; Vexiau, Romain; Bouloufa-Maafa, Nadia; Quéméner, Goulven; Dulieu, Olivier

    2016-05-01

    Recently, we have successfully created an ultracold sample of absolute ground-state NaRb molecules by two-photon Raman transfer of weakly bound Feshbach molecules. Here we will present the detailed spectroscopic investigations on both the excited and the rovibrational ground states for finding the two-photon path. For the excited state, we focus on the A1Σ+ /b3 Π singlet and triplet admixture. We discovered an anomalously strong coupling between the Ω =0+ and 0- components which renders efficient population transfer possible. In the ground state, the pure nuclear hyperfine levels have been clearly resolved, which allows us to create molecules in the absolute ground state directly with Raman transfer. This work is jointly supported by Agence Nationale de la Recherche (#ANR-13- IS04-0004-01) and Hong Kong Research Grant Council (#A-CUHK403/13) through the COPOMOL project.

  15. From dipolar to multipolar interactions between ultracold Feshbach molecules

    NASA Astrophysics Data System (ADS)

    Quéméner, Goulven; Lepers, Maxence; Luc-Koenig, Eliane; Dulieu, Olivier

    2016-05-01

    Using the multipolar expansion of electrostatic and magnetostatic potential energies, we characterize the long-range interactions between two weakly-bound diatomic molecules, taking as an example the paramagnetic Er2 Feshbach molecules which were produced recently. The interaction between atomic magnetic dipoles gives rise to the usual R-3 leading term of the multipolar expansion, where R is the intermolecular distance. We show that additional terms scaling as R-5, R-7 and so on also appear, which are strongly anisotropic with respect to the orientation of the molecules. These terms can be seen as effective molecular multipole moments reflecting the spatial extension of the molecules which is non-negligible compared to R. We acknowledge the financial support of the COPOMOL project (ANR-13-IS04-0004) from Agence Nationale de la Recherche.

  16. Shielding ultracold dipolar molecular collisions with electric fields

    NASA Astrophysics Data System (ADS)

    Quéméner, Goulven; Bohn, John

    2016-05-01

    The prospect for shielding ultracold dipolar molecules from inelastic and reactive collisions is investigated. Molecules placed in their first rotationally excited states are found to exhibit effective long-range repulsion for applied electric fields above a certain critical value. This repulsion can safely allow the molecules to scatter while reducing the risk of inelastic or chemically reactive collisions. Several molecular species of molecules of experimental interest such as NaRb, NaK, RbSr, SrF, BaF, and YO, are considered and all are shown to exhibit orders of magnitude suppression in quenching rates in a sufficiently strong laboratory electric field. We acknowledge the financial support of the COPOMOL project (ANR-13-IS04-0004) from Agence Nationale de la Recherche and the ARO MURI Grant No. W911NF-12-1-0476.

  17. How was the UNAIDS drug access initiative implemented in Chile?

    PubMed Central

    Brousselle, Astrid; Champagne, François

    2012-01-01

    In 1997, UNAIDS decided to implement Drug Access Initiatives (DAI) in four different pilot-countries. We studied the implementation of the DAI in Chile as part of the evaluation program conducted by the ‘Agence Nationale de Recherche sur le SIDA’ (ANRS/France). The objective was to understand how the politico-organizational dynamic influenced the implementation process of the DAI. Approximately 50 semi-directed interviews and observation activities were conducted with the actors who participated in the implementation of the DAI or who played a role in the HIV/AIDS context. The program theory models were established and their evolution analyzed. This article offers an original analysis of an international HIV/AIDS drug access program that was put in place at a time when such programs were seen as a priority by international and governmental institutions. It also offers some insights for the creation of international projects that will be locally implemented. PMID:23230344

  18. (Low-level waste disposal facility siting and site characterization)

    SciTech Connect

    Mezga, L.J.; Ketelle, R.H.; Pin, F.G.; Van Hoesen, S.D.

    1985-10-25

    A US team consisting of representatives of Oak Ridge National Laboratory (ORNL), Savannah River Plant (SRP), Savannah river Laboratory (SRL), and the Department of Energy Office of Defense Waste and Byproducts Management participated in the fourth meeting held under the US/French Radioactive Waste Management Agreement between the US Department of Energy and the Commissariat a l'Energie Atomique. This meeting, held at Agence Nationale pour les Gestion des Dechets Radioactifs' (ANDRA's) Headquarters in Paris, was a detailed, technical topical workshop focusing on Low-Level Waste Disposal Facility Siting and Site Characterization.'' The meeting also included a visit to the Centre de la Manche waste management facility operated by ANDRA to discuss and observe the French approach to low-level waste management. The final day of the meeting was spent at the offices of Societe Generale pour les Techniques Nouvelles (SGN) discussing potential areas of future cooperation and exchange. 20 figs.

  19. Formation of ultracold polar ground state molecules via an optical process

    NASA Astrophysics Data System (ADS)

    Dulieu, Olivier; Borsalino, Dimitri; Orban, Andrea; Vexiau, Romain; Londono-Florez, Beatriz; Crubellier, Anne; Luc, Eliane; Bouloufa-Maafa, Nadia

    2015-05-01

    Based on spectroscopic studies available in the literature completed by accurate ab initio calculations for potentail energy curves, spin-orbit couplings, and transition dipole moments, we investigate several optical coherent schemes to create ultracold bosonic and fermionic ultracold polar molecules in their absolute rovibrational ground level, starting from a weakly bound level of their electronic ground state manifold. The processes rely on the existence of convenient electronically excited states allowing an efficient stimulated Raman adiabatic transfer (STIRAP) of the level population. Illustrations are given for KRb and KCs. A model for the hyperfine structure of the excited molecular states is also presented. Supported by Agence Nationale de la Recherche (ANR), project COPOMOL (# ANR-13-IS04-0004-01).

  20. Hydraulic Monitoring of Low-Permeability Argillite at the Meuse/Haute Marne Underground Research Laboratory

    NASA Astrophysics Data System (ADS)

    Delay, Jacques; Cruchaudet, Martin

    ANDRA (Agence Nationale pour la Gestion de Déchets Radioactifs) has developed an electromagnetic permanent gauge (EPG) for long term monitoring of pore pressures in low permeability Callovo-Oxfordian argillites. The EPG is a pressure gauge that is permanently cemented into a borehole with no wire or tubing connections. The EPG transmits its data electromagnetically through the rock. Improvements in batteries have extended the life of the EPG to six years or more. Data from EPG installations in two holes near ANDRAs underground laboratory provide information on hydraulic conductivity and head. The heads in the argillites of the laboratory site are higher than heads in the two encasing carbonate units. These anomalous overpressures provide evidence for the very low permeability of the rock. Possible mechanisms for the overpressure include osmotic flows due to chemical potential gradients or delayed responses to the evolution of the regional groundwater hydrodynamics.

  1. The UT 8 February 2013 Sila-Nunam Mutual Event & Future Predictions

    NASA Astrophysics Data System (ADS)

    Benecchi, Susan D.; Noll, K.; Thirouin, A.; Ryan, E.; Grundy, W.; Verbiscer, A.; Doressoundiram, A.; Hestroffer, D.; Beaton, R.; Rabinowitz, D.; Chanover, N.

    2013-10-01

    A mutual event of the Kuiper Belt binary system (79360) Sila-Nunam was observed over 15.47 hours on UT 8 February 2013 by a coordinated effort at four telescopes: Telescopio Nationale Galileo in the Canary Islands, the du Pont telescope at Las Campanas Observatory, ARC at Apache Point Observatory and the IRTF on Mauna Kea. It is the first full event observed from start to finish for this binary system. The lightcurve is consistent with two objects of similar, but perhaps not identical, size and albedo. We will present the results from this event and predictions for future events which have been refined by this and other mutual event observations obtained since the events began.

  2. Phase Diagram Modelling: Nickel - Aluminum - Chromium System

    DTIC Science & Technology

    1998-04-01

    0.79850E-21 0.10305E-22 0.27743E-25 0.12188E-25 N2 Ni Cr Al A120 CrO NO CrN N AlO O NiO N20 Cr02 N3 (AlO)2 AIN Al 2 02 A102 N02...Defence SA MAJESTE LA REINE EN DROIT DU CANADA (1998) Defense Nationale Canada r> o DEPARTMENT OF NATIONAL DEFENCE - CANADA IWMHlBU’flOi Approved...Jaansalu Air Vehicle Research Detachment The Ni-Al- Cr system is of importance to the gas turbine industry as it forms the basis for protective

  3. The leopard in the garden: life in close quarters at the Museum d'Histoire Naturelle.

    PubMed

    Burkhardt, Richard W

    2007-12-01

    French naturalists at the Muséum Nationale d'Histoire Naturelle in Paris in the early nineteenth century recognized that their individual and collective successes were intimately linked to questions of power over specimens. France's strength abroad affected the growth of the museum's collections. At the museum, preserving, naming, classifying, displaying, interpreting, and otherwise deploying specimens went hand in hand with promoting scientific theories, advancing scientific careers, and instructing the public. The control of specimens, both literally and figuratively, was the museum's ongoing concern. The leopard in this essay's title, a live specimen confiscated from the streets of Paris in 1793, serves here to represent the tensions created in an existing order of things by the introduction of a potentially disruptive agent. The essay explores the life of the museum and the interrelations among its naturalists, the special challenges created by the establishment of a menagerie, and the histories of particular specimens and ideas.

  4. The European "clinical trial" regulation; relationship with the Jardé Act: a Giens workshop.

    PubMed

    Lemaire, François; Marchenay, Brigitte; Chassany, Olivier; Barthélémy, Philippe; Bouzzagou, Mohamed; Comet, Denis; Delval, Cécile; Dubray, Claude; Fouret, Cécile; Frija-Orvoen, Elisabeth; Gambotti, Laetitia; Lamarque, Véronique; d'Orsay, Geneviève; Plattner, Valérie; Sibenaler, Claire; Roux, Jacques; Thoby, Frédérique

    2015-01-01

    In May 2014, the European Union Parliament and Council published a new regulation on clinical trials on medicinal products for human use, which is designed to replace Directive 2001/20/EC. It will not come into effect until 2016. Nevertheless, it is essential to examine its relationship with national legislation, i.e. the Jardé Act, whose implementation has been delayed pending publication of the European regulation. The Giens workshop identified and examined the various issues that this relationship is bound to raise. In particular, it looked at trial methodology assessment procedures, the working relationship between the French National Agency of Drug Safety and Health Products (Agence Nationale de Sécurité du Médicament et des Produits de Santé, ANSM) and ethics committees during the authorization application evaluation phase, review of post-authorization/registration studies on medicinal products and medical devices, and data transparency.

  5. A little known episode in the life of the future revolutionary Fabre d'Eglantine: his involvement in mephitism.

    PubMed

    Olry, Régis

    2009-06-01

    On one hand we have Philippe-François-Nazaire Fabre, known as Fabre d'Eglantine, an undistinguished playwright, who, in September 1792, during the French Revolution, was elected a member of the Convention nationale and voted for the execution of Louis XVI in January 1793. On the other hand we have Jean-Antoine-Michel-Dieudonné Janin de Combe-Blanche, one of the most famous ophthalmologists of the eighteenth century, raised to the peerage in 1787, physician to crowned heads and dignitaries of the Church. These two men were diametrically opposed, but were brought together by chance, shortly before the outbreak of the French Revolution, by a pamphlet on mephitism.

  6. [Study on two manuscripts with colored illustrations collected in France].

    PubMed

    Liu, Yu-Ping; Cao, Hui

    2013-09-01

    Two manuscripts with colored illustrations in French libraries were investigated. The research showed that: the first manuscript with colored pictures include 2 volumes, titled Animaux et Plantes de Chine collected in Library of Museum National d'Historie Naturelle (MNHN);the other manuscript with colored pictures has only 1 volume, titled Botanique Chinoise collected in Library of Societe Asiatique, College de France, which were identified as illustrations of Ben cao gang mu (Compendium of Materia Medica) (1640 edition) by Li Shi-zhen. These pictures were copied by P. d'Incarville, and are similar to Plantes fleurs et arbres de Chine in Bibliotheque de l'Institut de Franceand, Collection de Plantes Veneneuses de la Chine Gravees et Imprimees en Couleurs par les Missionnaries Jesuites in Bibliotheque Nationale de France, respectively. The latter two manuscripts were identified as illustrations of Ben cao pin hui jing yao (Essential Collections of Materia Medica) (1700 edition).

  7. Spatially resolved optical-emission spectroscopy of a radio-frequency driven iodine plasma source

    NASA Astrophysics Data System (ADS)

    Dedrick, James; Doyle, Scott; Grondein, Pascaline; Aanesland, Ane

    2016-09-01

    Iodine is of interest for potential use as a propellant for spacecraft propulsion, and has become attractive as a replacement to xenon due to its similar mass and ionisation potential. Optical emission spectroscopy has been undertaken to characterise the emission from a low-pressure, radio-frequency driven inductively coupled plasma source operating in iodine with respect to axial distance across its transverse magnetic filter. The results are compared with axial profiles of the electron temperature and density for identical source conditions, and the spatial distribution of the emission intensity is observed to be closely correlated with the electron temperature. This work has been done within the LABEX Plas@Par project, and received financial state aid managed by the ``Agence Nationale de la Recherche'', as part of the ``Programme d'Investissements d'Avenir'' under the reference ANR-11-IDEX-0004-02.

  8. Canadian Forces in Joint Fires Support - Human Factors Analysis: Coalition Operations

    DTIC Science & Technology

    2010-08-01

    Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2010 DRDC Atlantic CR 2009-203 i Abstract...données (méthode de décision critique et entrevues structurées), à faire la synthèse et l’interprétation des données, à formuler les questions, les...avons fait appel à la méthode de décision critique et à des entrevues structurées, à une synthèse des données par des spécialistes des facteurs

  9. 42nd Congress of the "Groupe Français des Pesticides" (French Group of Pesticide research--GFP 2012) ENSIP, Poitiers, France, 30 May-1 June 2012.

    PubMed

    Chollet, Jean-François; Couderchet, Michel; Bonnemain, Jean-Louis

    2014-04-01

    The 42nd congress of the "Groupe Français des Pesticides" (French Group of Pesticide research--GFP 2012) took place 30 May-1 June at the "École Nationale Supérieure d’Ingénieurs de Poitiers" (ENSIP), a French generalist engineering grande école in Poitiers. Its focus is on the protection of the environment and is part of the University of Poitiers, one of the oldest universities in Europe. GFP is an annual conference where the latest developments in the field of pesticide research are presented. The topics most commonly discussed mainly concern environmental quality, monitoring, fate, and transfer of pesticides in the environment or risks associated with use of pesticides, but every year a key theme sets the tone. For this 42nd edition, the theme "Innovative strategies for plant protection" was retained.

  10. Cruising the ocean from space with Jason-1

    NASA Astrophysics Data System (ADS)

    Mønard, Yves; Escudier, Philippe; Fu, Lee; Kunstmann, Gary

    The exceptional results obtained from the TOPEX/POSEIDON (T/P) mission (see references and recommended reading list at end of this piece) have convinced scientists to continue the research activities needed to improve our understanding of ocean circulation and its interaction with climate. High-accuracy radar altimeter missions alone can provide continuous global observations of ocean circulation.Soon after the launch of T/P in August 1992 and following a comprehensive analysis of the system's performance, the T/P missions Science Working Team recommended that studies be engaged as a follow-on. Early in 1993, the Centre Nationale d Etudes Spatiales France (CNES) and the U.S. National Aeronautics and Space Administration (NASA) agreed to jointly build and operate this follow-on satellite, Jason-1, to be launched early in 2001. Fittingly, the new satellite is named after the leader of the Argonauts famous quest to recover the Golden Fleece.

  11. Report of activities in the Gas and Plasma Physics Laboratory (LPGP) of the Paris-South University, April - May 1991

    NASA Astrophysics Data System (ADS)

    Ferreira, Jose Leonardo

    This report describes the activities in a project to study waves and turbulence in plasmas which are being conducted by the French LAP and the LPGP. Studies aimed at studying resonant absorption of electromagnetic waves in quiescent plasma with a controlled density gradient were conducted in April and May. These studies are serving as a basis for assembling an experiment on generation of nonlinear Langmuir waves through collision of two electromagnetic waves of different frequencies. Also conducted during this period, in agencies of the LAP, were studies on the viability of constructing a magnetized quiescent plasma machine for whistler wave research. The plasma wave and turbulence studies program in France was concluded with a visit to the space plasma experiments in progress at the Centre D'Etude Spatiale des Reyonnements, located in the Complex Scientifique de Rangueil in Toulouse.

  12. Allergie respiratoire et “sunko”: une association rare, à propos d'une observation

    PubMed Central

    Ngombe, Léon Kabamba; Kangulu, Ignace Bwana; Nzaji, Michel Kabamba

    2014-01-01

    Il est rapporté dans ce texte un cas d'allergie respiratoire ayant fait probablement suite à une consommation d'un tabac sans fumé couramment utilisé en République Démocratique du Congo, le « Sunko ». Une rhinite et un asthme allergiques sont les cas. Cette observation permet d'attirer l'attention du monde scientifique à mettre sur pieds des études concernant la composition et les effets du Sunko pour appréhender cette association, puis d'informer l'opinion sur les dangers que courent les consommateurs de ce type de tabac et de faire la revue de la littérature. PMID:25426218

  13. Making Time for Spacetime: The Story of a National Science Cafe Effort

    NASA Astrophysics Data System (ADS)

    Redmond, Kendra; Chakrabarti, Anish

    2012-03-01

    Science Cafes are live and lively events that take place in casual settings such as coffeehouses or bars, are open to everyone, and feature an engaging conversation with a scientist about a compelling scientific topic. The Science Cafe movement in the United States is a grassroots effort to really engage the public in discussions about science and its relevance to society, inspired by the United Kingdom Cafe Scientifique organization. With support from NOVA and the related website sciencecafes.org, a number of Society of Physics Students chapters hosted local Cosmic Cafes (cosmic themed science cafes) in late 2011 and early 2012. This presentation will discuss the goals and models of the Science Cafe movement, the Cosmic Cafe effort, lessons learned, and how you can get involved.

  14. The new powder diffractometer D1B of the Institut Laue Langevin

    NASA Astrophysics Data System (ADS)

    Puente Orench, I.; Clergeau, J. F.; Martínez, S.; Olmos, M.; Fabelo, O.; Campo, J.

    2014-11-01

    D1B is a medium resolution high flux powder diffractometer located at the Institut Laue Langevin, ILL. D1B a suitable instrument for studying a large variety of polycrystalline materials. D1B runs since 1998 as a CRG (collaborating research group) instrument, being exploited by the CNRS (Centre National de la Recherche Scientifique, France) and CSIC (Consejo Superior de Investigaciones Cientificas, Spain). In 2008 the Spanish CRG started an updating program which included a new detector and a radial oscillating collimator (ROC). The detector, which has a sensitive height of 100mm, covers an angular range of 128°. Its 1280 gold wires provide a neutron detection point every 0.1°. The ROC is made of 198 gadolinium- based absorbing collimation blades, regular placed every 0.67°. Here the present characteristics of D1B are reviewed and the different experimental performances will be presented.

  15. Astronomie et chronoligie chez Newton - arguments astronomiques à l'appui de la chronologie de Newton (Astronomical arguments in Newton's Chronology)

    NASA Astrophysics Data System (ADS)

    Nazé, Yaël

    2012-12-01

    In his Chronology, Newton uses astronomical "evidence" to support its extreme rejuvenation of ancient times. These elements, having a scientific varnish, provide some credibility to the work. They have been fiercely debated for a century, with a gradual undermining of Newton's assumptions. However, this has not dented the prestige of the English scientist. Dans sa Chronologie, Newton utilise des "preuves" astronomiques pour appuyer son rajeunissement extreme des epoques anciennes. Ces elements, au vernis scientifique, donnent une credibilite certaine a l'ensemble. Ils ont donc ete aprement discutes, les debats sapant petit a petit les hypotheses du savant anglais pour finalement porter un coup mortel a l'ensemble. Cela n'a toutefois pas entame le prestige du savant anglais.

  16. Préface

    NASA Astrophysics Data System (ADS)

    Mazière, D.

    2003-03-01

    Le colloque de métallurgie est traditionnellement organisé depuis 45 ans par des enseignants du DEA Métallurgie et Matériaux et un comité scientifique choisi chaque annee en liaison avec le thème traité. Les étudiants de ce DEA, qui est habilité entre Paris XI, Paris VI, l'École des Mines de Paris, l'École Centrale de Paris, l'École de Chimie Paris et I'INSTN, sont invités à participer à ce colloque et aux débats scientifiques qui s'y déroulent. Des conférences invitées à caractère pédagogique permettent d'introduire les différents thèmes abordés qui sont ensuite développés dans des presentations plus novatrices. Cette manifestation a pour ambition de favoriser la rencontre de scientifiques d'horizons divers venant de milieux académiques ou industriels entre eux et avec les étudiants et thésards. Cette 45e édition, dont les comptes rendus sont publiés ici, s'est focalisée sur les effets des surfaces et des interfaces sur la rupture des matériaux. Les conférences et les posters ont été repartis suivant les thématiques ci-dessous : - cohésion, ségrégations et rupture ; - compétition entre rupture fragile et plasticité ; - germination et propagation initiale des fissures ; - decohésion d'interfaces dans les milieux revêtus ; - aspects statistiques de la rupture ; - effets d'environnement sur la rupture. Ce colloque a réuni, du 25 au 27 juin 2002, 50 participants provenant d'universités ou grandes écoles (11), du CEA (18), du CNRS (17) et de l'industrie ou de centres de recherche associés (4). Vingt sept communications dont vingt orales ont illustré ces thématiques. Dix-neuf d'entre elles sont développés dans cet ouvrage. Il me revient enfin d'annoncer la suspension des colloques de I'INSTN dans la forme qui leur était donnée jusqu'à ce jour. Une réflexion paraît nécessaire avant de proposer éventuellement une nouvelle formule plus en adéquation avec les besoins et les souhaits de la communauté scientifique

  17. The career paths of women (and men) in French research.

    PubMed

    de Cheveigné, Suzanne

    2009-02-01

    This paper presents results from a qualitative study of perceptions of science careers in the Centre National de la Recherche Scientifique (CNRS), the main research institution in France. Its aim is to understand the 'glass ceiling' effect, which reduces the proportion of women at the higher levels of the career hierarchy. Long interviews were carried out with men, as well as women, support staff and researchers. Factors such as tension between individual and collective dimensions of research activity, and long-term time-management problems, were identified: these affect both men and women but in different ways. Organizations bear an important responsibility through the way they reinforce or alleviate difficulties that women and men face in contributing to scientific research at all levels.

  18. A la recherches d'autres mondes - les exoplanètes

    NASA Astrophysics Data System (ADS)

    Nazé, Yaël

    2013-10-01

    Habiter ailleurs que sur Terre, en dehors du système solaire, est-ce vraiment possible ? Est-ce que la vie existe en dehors du Système solaire et comment la chercher ? Ces questions sont celles que les hommes et les femmes se posent et celles qu'ils se sont posées de tout temps. Les scientifiques n'échappent pas à cette règle et nous vivons à une époque fascinante où cette recherche évolue extrêmement vite : ils ont découvert d'autres lieux potentiellement habitables ou habités, les exoplanètes, des planètes tournant autour d'autres soleils dans l'univers. À ce jour, plus de 900 exoplanètes ont ainsi été détectées

  19. Design considerations for solar furnace focal zone apparatus

    SciTech Connect

    Sievers, R.H. Jr.; Knasel, T.M.; McDonnell, M.; Gordon, B.; Woods, S.; Malinowski, R.

    1981-01-01

    Science Applications, Inc. has used the principal solar furnaces in conjunction with its study of the effect of high thermal fluxes and fluences on soil surfaces for the Defense Nuclear Agency. Apparatus to perform these tests has evolved from tests on the furnaces at the White Sands Missile Range, Georgia Institute of Technology in Atlanta; Centre National de Recherche Scientifique in Font Romeu, France; and Kirtland AFB, NM over the past 6 years. The apparatus is still evolving as it is adapted to additional furnaces and to obtain a greater variety of data. The evolution of the apparatus is traced to illustrate the interaction of experiment objectives; furnace capabilities, configuration, and support; apparatus design; data collection; and response to lessons learned.

  20. Design of a flux diverter and containment tube with results of tests at ACTF and CNRS. [For testing response of soils to thermal pulse of nuclear detonations

    SciTech Connect

    Gordon, B.A.; Knasel, T.M.; Sievers, R.; Bomar, S.; Royere, C.; McDonnel, M.D.

    1980-01-01

    Obtaining empirical data on the response of soils and changes in the overlying air due to the thermal pulse of nuclear detonations required development of special test apparatus and use of high fluxes in a large solar furnace. The development of such apparatus, based on non-imaging optic principles; the influence of solar furnace test series in which the apparatus and instrumentation have been tested for thoroughput, durability, and suitability for meeting the requirements are discussed. Tests were conducted at the Advanced Components Test Facility and the Centre National de la Recherche Scientifique 1 MW solar furnace. These tests resulted in apparatus redesign, and change in procedures and instrumentation in preparation for further testing.

  1. Comprehensive Approach Workshop: Hard Problem First Steps

    DTIC Science & Technology

    2011-10-01

    effectuer les premières étapes de la gestion et la résolution du problème difficile. Il a compris la définition et la portée du problème difficile...initiales comprenaient ceux de la scène et la gestion de la science ainsi que pour faire approuver au début de l’activité scientifique des partenaires...mais aussi pilote d’essai les premières étapes vers la gestion et la résolution des problèmes difficiles en général. Les participants à l’atelier ont

  2. Seminar Andrej Sacharov

    ScienceCinema

    None

    2016-07-12

    A l'occasion de son 63me anniversaire 2 orateurs rendent hommage à A.Sacharov, physicien russe et né à Moscou, pour ses accomplissements scientifiques et son courage. A.Sacharov a dénoncé les dangers de la radioactivité et a tenté de persuader les autorités soviétiques de supprimer une série de test après le developpement de la bombe atomique en 1949 et la bombe à hydrogène en 1953 par un groupe de chercheurs soviétiques. Il a obtenu le prix Nobel en 1975.

  3. Challenges to reestablishment of free-ranging populations of black-footed ferrets

    USGS Publications Warehouse

    Biggins, D.E.; Godbey, J.L.

    2003-01-01

    The black-footed ferret (Mustela nigripes) of North America is critically endangered due in part to its extreme specialization on formerly stable and abundant prairie dogs (Cynomys). Its close relative, the Siberian polecat (M. eversmannii) seems to have been subjected to a varying environment that was not conducive to specialization. One source of environmental variation in Asian steppes was plague (caused by Yersina pestis), which was absent from North America. Introduction of plague to North America presents serious challenges to ferret recovery. Partial solutions to other biological and political problems have been found, resulting in improved production in captivity, increased survival post-release, and thriving populations in plague-free South Dakota. ?? 2003 Acade??mie des sciences. Published by E??ditions scientifiques et me??dicales Elsevier SAS. All rights reserved.

  4. Cell scientist to watch - Virgile Viasnoff.

    PubMed

    Bobrowska, Anna

    2016-02-01

    Virgile earned his first degree in soft matter physics at the École Normale Superieure in Paris. He then moved to Johns Hopkins University in the USA to complete a Masters degree, before returning to Paris to pursue his PhD at the École supérieure de physique et de chimie industrielles (ESPCI) in Francois Lequeux's laboratory. In 2006, after two years as a postdoctoral fellow in the group of Amit Meller at Harvard, Vigile started his own lab at the Centre national de la recherche scientifique (CNRS) at ESPCI. Between 2010 and 2011, Virgile spent two years on sabbatical at the Mechanobiology Institute (MBI) at the University of Singapore. He now holds a dual appointment between CNRS and MBI, and his lab in Singapore investigates how the physical and biochemical parameters of the cellular microenvironment regulate cell-cell adhesion and cell fate.

  5. Artificial modification meeting reminder

    NASA Astrophysics Data System (ADS)

    Gordon, W. E.

    A symposium on artificial modification of the ionosphere by high-powered radio waves (V. V. Migulin, Honorary Chairman) will be held September 19-23, 1988, at the Scandic Hotel, Tromso, Norway. The symposium, sponsored by Union Radio Scientifique Internationale Commissions (URSI) G and H, is in the URSI series which started at Suzdal in 1983. Information on the scientific program is available from V.V. Migulin, U.S.S.R. Academy of Sciences, 103907, Moscow Center, Marx Avl8, U.S.S.R.; Peter Stubbe, Max- Planck-Institut fuer Aeronomy, D-3411 Katlenburg- Lindau 3, Federal Republic of Germany; or W.E. Gordon, Rice University, Space Physics and Astronomy Dept., Houston, TX 77251. For local arrangements information, contact Asgeir Brekke, Institute Matematisk Realfag, Aurora Observatory, Box 953, N-9001, Tromso, Norway.

  6. 25th Birthday Cern- Restaurant

    SciTech Connect

    2006-05-05

    Cérémonie du 25ème anniversaire du Cern avec plusieurs orateurs et la présence de nombreux autorités cantonales et communales genevoises et personnalités, directeurs généraux, ministres, chercheurs.... Le conseiller féderal et chef du département des affaires étrangères de la confédération Monsieur Pierre Aubert prend la parole pour célébrer à la fois les résultats très remarquables de la coopération internationale en matière scientifique, mais aussi la volonté politique des états européens de mettre en commun leurs ressources pour faire oeuvre d'avenir. Un grand hommage est aussi donné aux deux directeurs disparus, les prof.Bakker et Gregory.

  7. New life for the THEMIS solar telescope

    NASA Astrophysics Data System (ADS)

    Gelly, Bernard; Langlois, Maud; Moretto, Gil; Douet, Richard; Lopez Ariste, Arturo; Tallon, Michel; Thiébaut, Eric; Geyskens, Nicolas; Lorgeoux, Guillaume; Léger, Johnathan; Le Men, Claude

    2016-07-01

    The THEMIS solar telescope is building a classical adaptive optics (AO) system to be operating on the Sun in 2017. To make compatible its excellent dual beam spectropolarimetric features with the AO also requires a major refurbishment of the relay optics starting at the M2 and down to the spectrograph entrance. This paper presents the design parameters and expected performances of our AO system, and explains why and how we intend to control to a few percent the Mueller matrix of the whole optical path from the prime focus to the spectropolarimetric cameras. This project is co-funded by the European Union SOLARNET Project Ref.:312495, and the Centre National de la Recherche Scientifique.

  8. Master equation with quantized atomic motion including dipole-dipole interactions

    NASA Astrophysics Data System (ADS)

    Damanet, François; Braun, Daniel; Martin, John

    2016-05-01

    We derive a markovian master equation for the internal dynamics of an ensemble of two-level atoms including all effects related to the quantization of their motion. Our equation provides a unifying picture of the consequences of recoil and indistinguishability of atoms beyond the Lamb-Dicke regime on both their dissipative and conservative dynamics, and is relevant for experiments with ultracold trapped atoms. We give general expressions for the decay rates and the dipole-dipole shifts for any motional states, and we find analytical formulas for a number of relevant states (Gaussian states, Fock states and thermal states). In particular, we show that the dipole-dipole interactions and cooperative photon emission can be modulated through the external state of motion. The effects predicted should be experimentally observable with Rydberg atoms. FD would like to thank the F.R.S.-FNRS for financial support. FD is a FRIA Grant holder of the Fonds de la Recherche Scientifique-FNRS.

  9. Georges Lemaître and Stigler's Law of Eponymy

    NASA Astrophysics Data System (ADS)

    Block, David L.

    One of the greatest discoveries of modern times is that of the expanding Universe, almost invariably attributed to Hubble (Proceedings of the National Academy of Sciences of the United States of America 15:168, 1929). What is not widely known is that the original treatise by Lemaître (Annales de la Société Scientifique de Bruxelles, Sèrie A 47:49, 1927) contained a rich fusion of both theory and of observation. The French paper was meticulously censored when published in English: all discussions of radial velocities and distances, and the very first empirical determination of H 0 , were suppressed. Stigler's law of eponymy is yet again affirmed: no scientific discovery is named after its original discoverer (Merton, American Sociological Review 22(6):635, 1957). An appeal is made for a Lemaître Telescope naming opportunity, to honour the discoverer of the expanding universe.

  10. A model for the construction of elementary concepts

    NASA Astrophysics Data System (ADS)

    von Glasersfeld, Ernst

    1999-03-01

    In his paper Les épistémologies constructivistes: Un nouveau commencement (Sciences de la Société, n°40, 1997), Jean-Louis Le Moigne poses the question: "Le rêve d'une connaissance autoréférentielle se fondant sur elle-même, est sans doute fascinant … Mais est-il scientifiquement raisonnable?". Building on the work of Jean Piaget, I shall try to show through a developmental analysis of elementary, scientifically relevant concepts, such as `change', `object permanence', `space', and `time', that the notion of the thinking subject's construction of knowledge constitutes a more reasonable foundation for science than the traditional belief in the representation of objective reality.

  11. Strategic Passages.

    DTIC Science & Technology

    1987-01-01

    t e g y c o m p r is e s t h r e e p tia s e s . A n im p o r t a n t ap e i t k it t h e ita...34’Iratei_\\ <K,’Ic \\,W 1 c a n a l. A lte r u c c e s s i ve , id e n in g s a n d d e e p e n in g s , t h e . Ban t ic . I , ’ l i i (Jn h/ i...13(1- Winter 1980, 84-91 Treves, Tullio. Principe du consentement et recherche scientifique dans le nouveau droit de la mer. Revue g

  12. Astronomie, «arts» et artistes

    NASA Astrophysics Data System (ADS)

    Débarbat, Suzanne

    2011-06-01

    En 1665, Adrien Auzout (1622-1691) figure parmi les membres des cercles scientifiques qui fleurissent en France depuis une trentaine d'années. Une comète est apparue l'année précédente et il adresse à Louis XIV son «Ephéméride du Comète» [sic] correspondant à cette voyageuse. Cette épître permet de voir combien art et science sont pour lui étroitement associés. L'observatoire Royal créé deux ans plus tard illustrera cette interaction comme le montre l'examen de ses collections.

  13. Morocco, Kingdom of the young geologist!

    NASA Astrophysics Data System (ADS)

    Bouttemy, Franck

    2015-04-01

    The Kingdom of Morocco is a country of 33 million people where about thirty French schools enroll 32,000 students including a majority of Moroccans. The Rabat Center includes several institutions enrolling 5,700 students aged 10 to 18 years old whose High School René Descartes is directed by the A.E.F.E, "Agency for French Teaching Abroad". Sixteen professors teach S.V.T. "Sciences de la Vie et de la Terre" that focuses on biology and geology. The programs involved are French but the biology-geology colleagues seek to place the teaching of geology in the context of Morocco through the choice of Moroccan examples. (https://sites.google.com/site/aefesvtmaroc/) Morocco's geology lends itself to this approach! The laboratory is equipped with a seismometer in the network "Sismos to School" (https://sites.google.com/a/lycee-descartes.ma/rabt_sismo/home) and we have the equipment necessary for making thin sections of the Moroccan rocks for practical work on a polarizing microscope. We organize several field trips: On a half-day in the region of Rabat, 12-year old pupils of "5ème", learn about reading the landscape and studying sedimentary rocks such as marls and sandstones. On a 3-day excursion in the region of Azrou, the16-year old pupils of "première scientifique" study the tectonic context of formation of mineral resources. A 2-day trip in the region of Oulmès, the17-year old pupils of "terminale scientifique" (the last year in the French system finishing with the "baccalaureate") study continental crust, tectonics and geothermal energy. These field trips will be presented in this poster. Students make field studies: observation, testing, photography, drawing and taking notes. Some works are evaluated during the field trip, others are the subject of home work: preparing a slide show, an audio recording work...

  14. Regolith formation on asteroids via thermal fatigue

    NASA Astrophysics Data System (ADS)

    Murdoch, N.; Delbo, M.; Libourel, G.; Ganino, C.; Michel, P.; Verati, C.

    2012-09-01

    Space-based [12] and remote sensing observations [4] reveal that regolith - a layer of loose unconsolidated material - is present on all asteroids, including very small, sub km-sized near-Earth asteroids (NEAs) such as (25143) Itokawa [7]. Classically, regolith is believed to be produced by impacts of small particles hitting asteroid surfaces. Such explanation works for bodies whose gravity field is strong enough for substantial reaccretion of impact debris, but it fails to account for the ubiquitous presence of regolith also on small asteroids with weaker gravity. Several works [6, 5, 10] have proposed that the thermal fatigue due to a huge number of day/night temperature cycles is a process responsible for the formation of regolith on the Moon, Mercury, and on the NEA (433) Eros by fracturing boulders and rocks on their surfaces. However, this process lacks a demonstration. Here we present laboratory experiments of thermal cycling of meteorites - taken as analogue of asteroid surface material - to study under which conditions rock cracking on NEAs occurs. PROGRAMME BLANC EDITION 2011 Projet SHOCKS DOCUMENT SCIENTIFIQUE ANR-GUI-AAP-04 - Doc Scientifique 2011 5/46 Figure 1: Images to scale of all small bodies (asteroids and comets) visited so far by space missions, showing the great diversity in size, shape and surface characteristics. The largest body in the image is the 100 km-sized (21) Lutetia observed by the ESA mission Rosetta. The smallest, not visible in the image, is the 350 m-sized (25143) Itokawa visited by the JAXA mission Hayabusa. The regolith properties are found to be very different from one object to the other. As can be seen on Fig. 2, while it corresponds to fine particles (typical size < mm) on Eros, no such particles are found on Itokawa whose regolith is rather

  15. Hα kinematics of the Spitzer Infrared Nearby Galaxies Survey - II

    NASA Astrophysics Data System (ADS)

    Dicaire, I.; Carignan, C.; Amram, P.; Hernandez, O.; Chemin, L.; Daigle, O.; de Denus-Baillargeon, M.-M.; Balkowski, C.; Boselli, A.; Fathi, K.; Kennicutt, R. C.

    2008-04-01

    This is the second part of an Hα kinematics follow-up survey of the Spitzer Infrared Nearby Galaxies Survey (SINGS) sample. The aim of this paper is to shed new light on the role of baryons and their kinematics and on the dark/luminous matter relation in the star-forming regions of galaxies, in relation with studies at other wavelengths. The data for 37 galaxies are presented. The observations were made using Fabry-Perot interferometry with the photon-counting camera FaNTOmM on four different telescopes, namely the Canada-France-Hawaii 3.6-m, the ESO La Silla 3.6-m, the William Herschel 4.2-m and the Observatoire du mont Mégantic 1.6-m telescopes. The velocity fields are computed using custom IDL routines designed for an optimal use of the data. The kinematical parameters and rotation curves are derived using the GIPSY software. It is shown that non-circular motions associated with galactic bars affect the kinematical parameters fitting and the velocity gradient of the rotation curves. This leads to incorrect determinations of the baryonic and dark matter distributions in the mass models derived from those rotation curves. Based on observations made with the ESO 3.60-m telescope at La Silla Observatories under programme ID 076.B-0859 and on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France and the University of Hawaii. E-mail: isabelle@astro.umontreal.ca (ID);claude.carignan@umontreal.ca (CC) ‡ Visiting Astronomer, Canada-France-Hawaii Telescope, operated by the National Research Council of Canada, the Centre National de la Recherche Scientifique de France and the University of Hawaii.

  16. Celestial Treasury

    NASA Astrophysics Data System (ADS)

    Lachièze-Rey, Marc; Luminet, Jean-Pierre

    2001-07-01

    Throughout history, the mysterious dark skies have inspired our imaginations in countless ways, influencing our endeavors in science and philosophy, religion, literature, and art. Filled with 380 full-color illustrations, Celestial Treasury shows the influence of astronomical theories and the richness of illustrations in Western civilization through the ages. The authors explore the evolution of our understanding of astronomy and weave together ancient and modern theories in a fascinating narrative. They incorporate a wealth of detail from Greek verse, medieval manuscripts and Victorian poetry with contemporary spacecraft photographs and computer-generated star charts. Celestial Treasury is more than a beautiful book: it answers a variety of questions that have intrigued scientists and laymen for centuries. -- How did philosophers and scientists try to explain the order that governs celestial motion? -- How did geometers and artists measure and map the skies? -- How many different answers have been proposed for the most fundamental of all questions: When and how did Earth come about? -- Who inhabits the heavens--gods, angels or extraterrestrials? No other book recounts humankind's fascination with the heavens as compellingly as Celestial Treasury. Marc Lachièze-Rey is a director of research at the Centre National pour la Récherche Scientifique and astrophysicist at the Centre d'Etudes de Saclay. He is the author of The Cosmic Background Radiation (Cambridge, 1999), and and The Quest for Unity, (Oxford, 1999 ), as well as many books in French. Jean-Pierre Luminet is a research director of the Centre National pour la Rechérche Scientifique, based at the Paris-Meudon observatory. He is the author of Black Holes, (Cambridge 1992), as well as science documentaries for television.

  17. Organizational Strategies for Critical Transportation Infrastructure: Characteristics of Urban Resilience. The Case of Montreal.

    NASA Astrophysics Data System (ADS)

    Beauregard, Stéphane; Therrien, Marie-Christine; Normandin, Julie-Maude

    2010-05-01

    Organizational Strategies for Critical Transportation Infrastructure: Characteristics of Urban Resilience. The Case of Montreal. Stéphane Beauregard M.Sc. Candidate École nationale d'administration publique Julie-Maude Normandin Ph.D. Candidate École nationale d'administration publique Marie-Christine Therrien Professor École nationale d'administration publique The proposed paper presents preliminary results on the resilience of organizations managing critical infrastructure in the Metropolitan Montreal area (Canada). A resilient city is characterized by a network of infrastructures and individuals capable of maintaining their activities in spite of a disturbance (Godschalk, 2002). Critical infrastructures provide essential services for the functioning of society. In a crisis situation, the interruption or a decrease in performance of critical infrastructures could have important impacts on the population. They are also vulnerable to accidents and cascading effects because on their complexity and tight interdependence (Perrow, 1984). For these reasons, protection and security of the essential assets and networks are one of the objectives of organizations and governments. But prevention and recovery are two endpoints of a continuum which include also intermediate concerns: ensuring organizational robustness or failing with elegance rather than catastrophically. This continuum also includes organizational resilience (or system), or the ability to recover quickly after an interruption has occurred. Wildavsky (1988) proposes that anticipation strategies work better against known problems while resilience strategies focus on unknown problems. Anticipation policies can unnecessarily immobilize investments against risks, while resilience strategies include the potential for a certain sacrifice in the interests of a more long-term survival and adaptation to changing threats. In addition, a too large confidence in anticipation strategies can bring loss of capacity of an

  18. Préface

    NASA Astrophysics Data System (ADS)

    Mazière, D.

    2002-04-01

    Faisant suite aux deux précédents colloques "Matériaux pour les machines thermiques" et "Matériaux pour le nucléaire" , le colloque 2001 de l'INSTN intitulé "Matériaux pour les énergies propres" s'est focalisé sur les problèmes de matériaux encore à résoudre dans ce secteur industriel. Le colloque de métallurgie est traditionnellement organisé par des ense ignants du DEA Métallurgie et Matériaux et un comité scientifique choisi chaq ue année en liaison avec le thème traité. Les étudiants de ce DEA, qui est hab ilité entre Paris XI, Paris VI, l'Ecole des Mines de Paris, l'Ecole Centrale de Pari s et l'INSTN, sont invités à participer à ce colloque et aux débats scientifiques qui s'y déroulent. Des conférences invitées à caractère péda gogique permettent d'introduire les différents thèmes abordés qui sont ensuite développés dans des présentations plus novatrices. Cette manifestation a pour ambition de favoriser la rencontre de scientifiques d'horizons divers venant de milieux académiques ou industriels entre eux et avec les étudiants et thésards. Cette 44e édition, dont les comptes rendus sont publiés ici, a fait le point sur les problèmes de matériaux rencontrés lors de la production, du stockage et de la conversion des énergies dites propres en englobant lesprogrès constants des industriels de l'automobile. Ce colloque a réuni, du 26 au 28 juin 2001, 63 participants provenant d'universités ou grandes écoles (18), du CEA (17), du CNRS (10) et de l'industrie ou de centres de recherche associés. L'ensemble des problèmes de matériaux de ce secteur ont été examinés au cours des six sessions ci-dessous : dépollution des gaz d'échappement ; combustion catalytique en production thermique ; nouvelles batteries ; piles à combustibles ; production et stockage d'hydrogène ; production et stockage d'énergie solaire. Vingt huit communications dont vingt deux orales ont illustré les dével oppements en cours. Dix

  19. Paternité des articles et intérêts concurrents : une analyse des recommandations aux auteurs des journaux traitant de pratique pharmaceutique

    PubMed Central

    Courbon, Ève; Tanguay, Cynthia; Lebel, Denis; Bussières, Jean-François

    2014-01-01

    RÉSUMÉ Contexte : La présence d’auteurs honorifiques et fantômes ainsi que les intérêts concurrents représentent des difficultés bien documentées, liées à la publication d’articles scientifiques. Il existe des lignes directrices encadrant la rédaction et la publication de manuscrits scientifiques, notamment celles de l’International Committee of Medical Journal Editors (ICMJE). Objectifs : L’objectif principal de cette étude descriptive et transversale visait à recenser les instructions portant sur la paternité des articles et les intérêts concurrents provenant des recommandations aux auteurs des journaux traitant de pratique pharmaceutique. L’objectif secondaire visait à déterminer des mesures correctrices pour une paternité des articles plus transparente. Méthode : La recherche a débuté par l’identification des journaux traitant de pratique pharmaceutique. La consultation des instructions aux auteurs des journaux a permis ensuite de recenser les recommandations destinées à éviter les problèmes de paternité des articles et d’intérêts concurrents. Finalement, les membres de l’équipe de recherche se sont consultés afin de définir des mesures correctrices possibles à l’intention des chercheurs. Résultats : Des 232 journaux traitant de pharmacie, 33 ont été définis comme traitant de pratique pharmaceutique. Un total de 24 (73 %) journaux mentionnaient suivre la politique de l’ICMJE, 14 (42 %) demandaient aux auteurs de remplir un formulaire de déclaration d’intérêts concurrents au moment de la soumission de l’article, 17 (52 %) présentaient une définition de la qualité d’auteur et 5 (15 %) demandaient de détailler les contributions de chaque auteur. Une grille de 40 critères a été élaborée pour définir l’attribution du statut d’auteur. Conclusion : Moins de la moitié des journaux demandait aux auteurs de transmettre un formulaire de déclaration des intérêts concurrents au moment de la

  20. La supraconductivité a 100 ans !

    ScienceCinema

    None

    2016-07-12

    Il y a 100 ans, le 8 avril 1911, une découverte majeure était réalisée : celle de la supraconductivité. La supraconductivité est la caractéristique qu’ont certains métaux et alliages de perdre toute résistance électrique en dessous d’une température donnée. Cette renversante découverte, réalisée de manière presque fortuite par Kammerlingh Onnes de l’Université de Leyde (Pays-Bas) et son étudiant Gilles Holst, a ouvert un nouveau champ de recherche en physique et de fabuleuses perspectives d’applications technologiques. Du point de vue scientifique, la supraconductivité est en effet l’une des rares manifestations de la physique quantique à l’échelle macroscopique.  Du point de vue des retombées techniques, elle est porteuse d’applications majeures dans le domaine de la santé, des communications et de l’énergie. 100 ans après, les physiciens n’ont toujours pas fini d’explorer ce phénomène et ses applications. Le CERN abrite des applications de la supraconductivité à des échelles inédites. L’accélérateur de particules LHC, avec ses milliers d’aimants supraconducteurs répartis sur 27 kilomètres de circonférence, est en effet la plus grande application mondiale de la supraconductivité. Il ne pourrait exister sans elle.  Le CERN fête donc la découverte de la supraconductivité avec une conférence exceptionnelle donnée par Philippe Lebrun. Au cours de cette conférence, l’expérience historique de Kammerlingh Onnes sera reproduite. Philippe Lebrun racontera l’histoire de cette étonnante découverte, en la replaçant dans le contexte scientifique de l’époque. Il racontera les développements scientifiques et les applications du premier siècle de la supraconductivité. Conférence en français Merci de bien vouloir vous inscrire au : +41 22 767 76

  1. Démarche pour la mise à niveau d’un secteur de soins pharmaceutiques : le cas de l’hémato-oncologie pédiatrique

    PubMed Central

    Bussières, Jean-François; Robelet, Antoine; Therrien, Roxane; Touzin, Karine

    2010-01-01

    Contexte : Bien que le concept de pharmacie clinique ait été développé dans les années soixante, il existe une grande variété de programmes et une grande disparité entre les programmes en clinique externe et en hospitalisation, bénéficiant de la présence d’un pharmacien dans un secteur de soins. Objectif: Éprouver une méthode de mise à niveau des secteurs de soins pharmaceutiques en établissement de santé. Méthode : Il s’agit d’une étude descriptive se déroulant au Centre hospitalier universitaire Sainte-Justine, un établissement mère-enfant de 500 lits. Le secteur de soins pharmaceutiques ciblé pour illustrer la méthode de mise à niveau est l’hématologie-oncologie pédiatrique. La méthode comporte trois étapes, soit une revue de la documentation scientifique, un profil du secteur et une mise à jour du niveau de pratique selon un profil des activités pharmaceutiques dans le secteur avant et après la mise à niveau. Résultats : Au total, 108 articles ont été recensés et 22 ont été retenus à partir d’une recherche dans PubMed. Après une recherche manuelle complémentaire, 36 articles ont finalement été évalués. Parmi les articles retenus, on compte trois lignes directrices, 11 études de développement, une revue de la littérature scientifique, six études pré- et post-interventions et 15 études quasi expérimentales. Bien que les patients de ce secteur ne comptent que pour 5 % des admissions de l’hôpital, la complexité des cas est élevée tant sur le plan de la codification de l’épisode de soins que du potentiel d’intervention pharmaceutique par admission. Conclusion : Il existe peu de données illustrant une démarche de mise à niveau de la pratique dans un secteur de soins pharmaceutiques. Cette étude a éprouvé une méthode de mise à niveau dans un service d’hématologie-oncologie pédiatrique et comporte une revue de la documentation scientifique, un profil du secteur et une description des t

  2. Evaluation des retombees economiques des projets energetiques au Quebec : Analyse couts-avantages de la mini-centrale hydroelectrique de Val-Jalbert

    NASA Astrophysics Data System (ADS)

    Ossoro, Marcel Thierry

    Evaluer les retombees economiques d'un projet, cela consiste a evaluer le benefice du projet du point de vue de la collectivite. C'est le processus d'analyse, de mesure et d'appreciation de l'impact du projet, sur l'economie locale, regionale ou nationale. Il permet de prendre une decision optimale sur la faisabilite de l'investissement compte tenu de ses incidences sur l'ensemble des agents economiques. L'incoherence des approches et outils dans l'evaluation peut biaiser le calcul de l'impact net du projet, et par consequent, biaiser les termes de la hierarchisation des priorites en matiere d'investissement. Dans le cas des projets sensibles, necessitant de lourds investissements et beaucoup mediatises, comme cela est le cas des projets energetiques ; le biais peut s'averer desastreux et aboutir a une situation chaotique. La presente recherche porte sur l'evaluation des retombees economiques des projets energetiques au Quebec ; la pertinence et la coherence des outils et methodes d'evaluation. Elle est edifiee par une etude de cas. L'etude porte sur l'evaluation du projet de la mini-centrale hydroelectrique de Val Jalbert par la methode de l'analyse couts-avantages. Nous utilisons la methode des prix de reference selon l'approche de l'ONUDI. L'etude revele que le projet de la mini-centrale hydroelectrique de Val Jalbert repond positivement aux deux objectifs : l'efficience---maximisation de la consommation, et l'equite sociale---maximisation de la justice sociale. Il est donc considere, du point de vue de l'ONUDI, comme etant economiquement (ou socialement) rentable. L'analyse couts-avantages est un puissant evaluateur d'impact. Elle evalue le projet en l'integrant dans un cadre coherent d'analyses economiques, qui repose non seulement sur des valeurs nationales mais egalement, qui prend en compte les couts et avantages directs, indirects, internes et externes ; ce qui fait de l'outil, l'evaluateur le plus complet. A travers l'etude, nous montrons comment l

  3. Modélisation et simulation en régime stationnaire d'ateliers d'évaporation de sucreries à l'aide de l'équation d'état de Peng-Robinson

    NASA Astrophysics Data System (ADS)

    Rabi, M.; Bounahmidi, T.

    1999-03-01

    In this work the Peng-Robinson equation of state, previously adapted in our laboratory to predict physical and vapor-liquid equilibrium properties of sugar juices caracterised by the pseudo-components: sugar, amino acid ,carboxylic acid and cinders in aquesus solution, was tested in the modeling and simulation of the steady-state behaviour of multiple effect evaporation plants in sugar factory. The results of simulation has been compared to the real average measurements in the SUNABEL(Sucrerie Nationale de Betterave de Loukkos,Maroc) sugar factory, and showed that the Peng-Robinson equation of state can be used to predict, with a sufficient precision, of the steady-state behaviour of multiple effect evaporation plants in sugar factory. The originality of the model in comparison with the published others models consist in takening account of purity and natural of impurity in the juice. The simultanious modular approach is used in steady state process simulation. Dans ce travail l'équation d'état de Peng-Robinson, adaptée antérieurement dans notre laboratoire aux jus sucrés industriels en caractérisant ces derniers à l'aide de pseudo-composés sucre, acide aminé, acide carboxylique et cendre en solution dans l'eau, a ?été? testée pour la modélisation en régime stationnaire d'ateliers d'évaporation de sucreries. La confrontation des résultats de simulation à l'aide de ce modèle, avec des mesures moyennes observées sur l'atelier d'évaporation de la Sucrerie Nationale de Betterave du Loukkos (SUNABEL) Ksar El Kébir, a montré? que cette ?équation permet de prédire, avec une précision suffisante, les performances de l'atelier en régime stationnaire. L'originalité? du modèle développé, par rapport aux modèles proposés dans la littérature, réside dans la prise en compte de la pureté? et de la nature des impuretés présentes dans le jus. La simulation de l'atelier d'évaporation à l'aide de ce modèle a été menée en utilisant l

  4. 3. Côte D'Ivoire

    NASA Astrophysics Data System (ADS)

    Cisse, M'badiala

    1996-01-01

    Entreprendre une recherche sur la politique et la législation en matière d'éducation des adultes, qui couvre plusieurs secteurs, paraît une gageure pour plusieurs raisons: difficultés dans la constitution de plusieurs équipes de recherche avec plusieurs spécialistes ou personnes ressources, difficultés dans la collecte des données, étendue et complexité des domaines à explorer et des points à prendre en compte dans la rédaction, etc. En dépit de ces difficultés majeures, l'essentiel du travail a été accompli dans le souci de respecter les exigences imposées. A l'analyse, nous constatons que plusieurs partenaires interviennent dans la formation, l'éducation et l'encadrement des adultes, et que dans le secteur public, les structures ne sont pas "logées à la même enseigne": Si la formation professionnelle a bénéficié de conditions réellement favorables pour son expansion et son développement, les autres secteurs, sans avoir été négligés, n'ont pas connu les mêmes faveurs. Ainsi plusieurs lois et mesures importantes ont été votées et prises en vue de la dynamisation de la formation professionnelle, alors que le secteur de l'agriculture, qui est la base de succès du développement du pays et occupe 55% de la population, n'a pas bénéficié d'une véritable politique éducative en faveur des agriculteurs. Il en est de même pour l'alphabétisation. On déplore constamment l'absence de politique élaborée et appliquée à l'échelle nationale. Aucune mesure politique n'a été votée par l'Assemblée nationale, alors que l'alphabétisation devrait constituer le levier du développement de l'éducation des adultes en Côte d'lvoire.

  5. Ending neglect: providing effective childhood tuberculosis training for health care workers in Tanzania.

    PubMed

    Adams, L V; Olotu, R; Talbot, E A; Cronin, B J; Christopher, R; Mkomwa, Z

    2014-12-21

    Contexte : Structures de soins de santé à Dar es Salam, Pwani et Arusha, Tanzanie.Objectif : Evaluer les connaissances et pratiques du personnel de santé (HCW) un an après une formation spécifique à la tuberculose de l'enfant (TB).Schéma : Grâce à une enquête standardisée, nous avons interviewé un échantillon de complaisance de HCW offrant des soins à la fois généraux et spécialisés à des enfants.Résultats : Nous avons interviewé 117 HCW dans des dispensaires de TB, des centres de santé maternelle et infantile, des dispensaires pour le virus de l'immunodéficience humaine (VIH), des consultations externes et des services de pédiatrie dans 12 établissements. Un total de 81 HCW (62% d'infirmières, 74% de cliniciens) a affirmé avoir bénéficié de la formation nationale relative à la TB de l'enfant. La majorité a répondu correctement aux questions relatives au diagnostic de la TB de l'enfant, à son traitement et à la prise en charge conjointe de la TB et du VIH, quels que soient les antécédents de formation. La plupart ont dit demander en routine des radiographies pulmonaires, un test VIH et une recherche de contacts tuberculeux lors de l'évaluation des enfants. Moins de la moitié des HCW a affirmé recueillir des crachats en routine pour une culture mycobactérienne ou réaliser un test cutané à la tuberculine. La prescription de thérapie préventive par isoniazide (IPT) a été faite trois fois plus souvent par des HCW formés que par ceux qui ne l'avaient pas été (P < 0,05).Conclusion : En général, les connaissances en matière de TB de l'enfant étaient élevées et les pratiques conformes aux directives nationales. L'étude a identifié des lacunes spécifiques en matière de diagnostic, de traitement et d'utilisation de l'IPT afin de mieux cibler les futures formations.

  6. Foreword

    NASA Astrophysics Data System (ADS)

    Boutron, Claude; Ferrari, Christophe

    2003-05-01

    It is our pleasure to host the “12th International Conference on Heavy Metals in the Environment” in the city of Grenoble (France), in the heart of the Alps. This is the latest in this successful and popular series of conferences, which previously took place in Toronto (1975), London (1979), Amsterdam (1981), Heidelberg (1983), Athens (1985), New Orleans (1987), Geneva (1989), Edinburgh (1991), Hamburg (1995) and Ann Arbor (2000). Grenoble is one of the major research centres in Europe, with a very large number of researchers in various fields, especially Physics and Chemistry, Mathematics and Computer Sciences, Biology and Medicine, and Earth and Universe Sciences. There are two internationally recognized scientific Universities: Université Joseph Fourier (UJF), and Institut National Polytechnique de Grenoble (INPG). There are also the main research laboratories of various French and European governmental organizations such as Commissariat à l'énergie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Institut Laue Langevin (ILL), European Synchrotron Radiation Facility (ESRF) and Institut de Radio-Astronomie Millimètrique (IRAM). Finally, there are various hi-tech companies such as Hewlett Packard, ST Microelectronics, Schneider Electric and SGS-Thomson. There is a long tradition of research in the field of heavy metals in the environment, especially at the Laboratoire de Glaciologie et Géophysique de l'Environnement and at the Laboratoire de Géophysique Interne et Tectonophysique. These two volumes contain papers presented both in oral and poster sessions. The papers are not organised in order of presentation, but according to the alphabetical order of the family name of the first author of each paper. It is our pleasure to thank the authors for the excellent level of their submissions. We are also particularly grateful to Isabelle Houlbert and Laurence Castagné for editorial assistance. We would like to take this opportunity to

  7. Evaluation d'un scenario d'apprentissage favorisant la mobilisation des habiletes reliees au processus d'enquete

    NASA Astrophysics Data System (ADS)

    Blanchard, Samuel F. J.

    Les resultats au Programme international pour le suivi des acquis des eleves (PISA) demontrent que les jeunes neobrunswickois francophones se classent b un niveau significativement inferieur comparaiivement aux eleves anglophones du Nouveau-Brunswick, aux eleves des autres provinces canadiennes et se classent sous la moyenne internationale de tous les pays participants quant b la culture scientifique. L'evaluation de cette culture scientifique est basee sur une serie de savoirs, de savoir-faire et de savoir-etre reliee au processus d'enquete scolaire. Le processus d'enquete scolaire est une approche b l'apprentissage ou les eleves effectuent des recherches d'informations, discutent d'idees et entreprennent des investigations pour augmenter leur comprehension d'un probleme ou d'un sujet. Les recherches demontrent que le processus d'enquete scolaire est rarement une composante pedagogique importante de la salle de classe et les recherches portant sur l'implantation du processus d'enquete scolaire recommandent de rendre ce dernier plus accessible aux enseignantes et aux enseignants. Afin de rendre le processus d'enquete plus accessible aux enseignantes et aux enseignants, notre recherche porte sur l'evaluation de la valeur pedagogique d'un scenario d'apprentissage (PhaRoboS) concu specialement pour creer un environnement dans lequel les eleves auront plusieurs occasions a mobiliser les habiletes reliees au processus d'enquete. Les retombees de cette evaluation nous permettront d'offrir des pistes de remediations afin d'aider plus d'enseignantes et d'enseignants b creer un environnement dans lequel les eleves auront plusieurs occasions b mobiliser les habiletes reliees au processus d'enquete. Cette evaluation s'est faite a partir d'une methodologie inspiree de l'evaluation pour fin d'amelioration d'un objet pedagogique. L'analyse des donnees qualitatives recueillies aupres des eleves et de leur enseignante d'une ecole francophone du Nouveau-Brunswick semble montrer que

  8. The MiMeS survey of magnetism in massive stars: CNO surface abundances of Galactic O stars

    NASA Astrophysics Data System (ADS)

    Martins, F.; Hervé, A.; Bouret, J.-C.; Marcolino, W.; Wade, G. A.; Neiner, C.; Alecian, E.; Grunhut, J.; Petit, V.

    2015-03-01

    Context. The evolution of massive stars is still partly unconstrained. Mass, metallicity, mass loss, and rotation are the main drivers of stellar evolution. Binarity and the magnetic field may also significantly affect the fate of massive stars. Aims: Our goal is to investigate the evolution of single O stars in the Galaxy. Methods: For that, we used a sample of 74 objects comprising all luminosity classes and spectral types from O4 to O9.7. We relied on optical spectroscopy obtained in the context of the MiMeS survey of massive stars. We performed spectral modelling with the code CMFGEN. We determined the surface properties of the sample stars, with special emphasis on abundances of carbon, nitrogen, and oxygen. Results: Most of our sample stars have initial masses in the range of 20 to 50 M⊙. We show that nitrogen is more enriched and carbon and oxygen are more depleted in supergiants than in dwarfs, with giants showing intermediate degrees of mixing. CNO abundances are observed in the range of values predicted by nucleosynthesis through the CNO cycle. More massive stars, within a given luminosity class, appear to be more chemically enriched than lower mass stars. We compare our results with predictions of three types of evolutionary models and show that for two sets of models, 80% of our sample can be explained by stellar evolution including rotation. The effect of magnetism on surface abundances is unconstrained. Conclusions: Our study indicates that in the 20-50 M⊙ mass range, the surface chemical abundances of most single O stars in the Galaxy are fairly well accounted for by stellar evolution of rotating stars. Based on observations obtained at 1) the Telescope Bernard Lyot (USR5026) operated by the Observatoire Midi-Pyrénées, Université de Toulouse (Paul Sabatier), Centre National de la Recherche Scientifique of France; 2) at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada, the Institut

  9. Diffusion, diffraction des neutrons en temps réel et études réalisées in situ

    NASA Astrophysics Data System (ADS)

    Isnard, O.

    2003-02-01

    La diffusion des neutrons est une technique particulièrement efficace pour l'analyse en temps réel des processus réactionnels dans la matière. La diffraction de neutrons in situ a été développée très tôt sur les sources à haut flux tel que l'Institut Laue Langevin. Ces études nécessitent un flux de neutrons important et un détecteur couvrant un domaine angulaire le plus grand possible. Les neutrons offrent la spécificité d'être très peu absorbés par nombre de matériaux, cette faible absorption fait de la diffusion neutronique un excellent outil pour sonder la matière en volume et de manière non destructive. Cela permet en particulier d'utiliser des environnements d'échantillons complexes tout en conservant un flux raisonnable. La diffusion de neutrons en temps réel est donc très largement utilisée par diverses communautés scientifiques : sciences des matériaux, physiciens, chimistes... L'objet de ce cours est de donner les paramètres importants pour ce type d'étude et d'illustrer le propos à l'aide d'exemples pris dans des domaines scientifiques divers : électrochimie, magnétisme, métallurgie, chimie du solide. Après avoir présenté quelques repères méthodologiques sur les méthodes d'acquisition de données, des exemples montreront le fort potentiel de la diffusion neutronique en temps réel pour l'étude de la matière dans des conditions dynamiques. Enfin, nous donnerons aussi quelques conseils pour la visualisation, le dépouillement et l'analyse de ce type d'expérience. La diffusion des neutrons sur poudre est actuellement très bien adaptée aux études réalisées in situ. Cependant, nous verrons que la faisabilité d'études in situ s'étend à d'autres techniques expérimentales telles que la diffusion des neutrons aux petits angles et même la diffusion sur monocristal qui est en plein renouveau.

  10. Large-scale Periodic Variability of the Wind of the Wolf-Rayet Star WR 1 (HD 4004)

    NASA Astrophysics Data System (ADS)

    Chené, A.-N.; St-Louis, N.

    2010-06-01

    We present the results of an intensive photometric and spectroscopic monitoring campaign of the WN4 Wolf-Rayet (WR) star WR 1 = HD 4004. Our broadband V photometry covering a timespan of 91 days shows variability with a period of P = 16.9+0.6 -0.3 days. The same period is also found in our spectral data. The light curve is non-sinusoidal with hints of a gradual change in its shape as a function of time. The photometric variations nevertheless remain coherent over several cycles and we estimate that the coherence timescale of the light curve is of the order of 60 days. The spectroscopy shows large-scale line-profile variability which can be interpreted as excess emission peaks moving from one side of the profile to the other on a timescale of several days. Although we cannot unequivocally exclude the unlikely possibility that WR 1 is a binary, we propose that the nature of the variability we have found strongly suggests that it is due to the presence in the wind of the WR star of large-scale structures, most likely corotating interaction regions (CIRs), which are predicted to arise in inherently unstable radiatively driven winds when they are perturbed at their base. We also suggest that variability observed in WR 6, WR 134, and WR 137 is of the same nature. Finally, assuming that the period of CIRs is related to the rotational period, we estimate the rotation rate of the four stars for which sufficient monitoring has been carried out, i.e., v rot = 6.5, 40, 70, and 275 km s-1 for WR 1, WR 6, WR 134, and WR 137, respectively. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de Recherche Scientifique of France, and the University of Hawaii. Also based on observations obtained at the Observatoire du Mont Mégantic with is operated by the Centre de Recherche en Astrophysique du Québec and the Observatoire de

  11. Magnetic field structure in single late-type giants: The weak G-band giant 37 Comae from 2008 to 2011

    NASA Astrophysics Data System (ADS)

    Tsvetkova, S.; Petit, P.; Konstantinova-Antova, R.; Aurière, M.; Wade, G. A.; Palacios, A.; Charbonnel, C.; Drake, N. A.

    2017-03-01

    Aims: This work studies the magnetic activity of the late-type giant 37 Com. This star belongs to the group of weak G-band stars that present very strong carbon deficiency in their photospheres. The paper is a part of a global investigation into the properties and origin of magnetic fields in cool giants. Methods: We use spectropolarimetric data, which allows the simultaneous measurement of the longitudinal magnetic field Bl, line activity indicators (Hα, Ca ii IRT, S-index) and radial velocity of the star, and consequently perform a direct comparison of their time variability. Mean Stokes V profiles are extracted using the least squares deconvolution (LSD) method. One map of the surface magnetic field of the star is reconstructed via the Zeeman Doppler imaging (ZDI) inversion technique. Results: A periodogram analysis is performed on our dataset and it reveals a rotation period of 111 days. We interpret this period to be the rotation period of 37 Com. The reconstructed magnetic map reveals that the structure of the surface magnetic field is complex and features a significant toroidal component. The time variability of the line activity indicators, radial velocity and magnetic field Bl indicates a possible evolution of the surface magnetic structures in the period from 2008 to 2011. For completeness of our study, we use customized stellar evolutionary models suited to a weak G-band star. Synthetic spectra are also calculated to confirm the peculiar abundance of 37 Com. Conclusions: We deduce that 37 Com is a 6.5 M⊙ weak G-band star located in the Hertzsprung gap, whose magnetic activity is probably due to dynamo action. Based on observations obtained at the Télescope Bernard Lyot (TBL, Pic du Midi, France) of the Midi-Pyrénées Observatory which is operated by the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France and Université de Toulouse, and at the Canada-France-Hawaii Telescope (CFHT) which is

  12. A model for evaluating radiological impacts on organisms other than man for use in post-closure assessments of geological repositories for radioactive wastes.

    PubMed

    Thorn, M C; Kelly, M; Rees, J H; Sánchez-Friera, P; Calvez, M

    2002-09-01

    Bioaccumulation and dosimetric models have been developed that allow the computation of dose rates to a wide variety of plants and animals in the context of the deep geological disposal of solid radioactive wastes. These dose rates can be compared with the threshold dose rates at which significant deleterious effects have been observed in field and laboratory observations. This provides a general indication of whether effects on ecosystems could be observable, but does not quantify the level of those effects. To address this latter issue, two indicator organisms were identified and exposure-response relationships were developed for endpoints of potential interest (mortality in conifers and the induction of skeletal malformations in rodents irradiated in utero). The bioaccumulation, dosimetry and exposure-response models were implemented and used to evaluate the potential significance of radionuclide releases from a proposed deep geological repository for radioactive wastes in France. This evaluation was undertaken in the context of a programme of assessment studies being performed by the Agence nationale pour la gestion des déchets radioactifs (ANDRA).

  13. Forensic entomology: implementing quality assurance for expertise work.

    PubMed

    Gaudry, Emmanuel; Dourel, Laurent

    2013-09-01

    The Department of Forensic Entomology (Institut de Recherche Criminelle de la Gendarmerie Nationale, France) was accredited by the French Committee of Accreditation (Cofrac's Healthcare section) in October 2007 on the basis of NF EN ISO/CEI 17025 standard. It was the first accreditation in this specific field of forensic sciences in France and in Europe. The present paper introduces the accreditation process in forensic entomology (FE) through the experience of the Department of Forensic Entomology. Based upon the identification of necrophagous insects and the study of their biology, FE must, as any other expertise work in forensic sciences, demonstrate integrity and good working practice to satisfy both the courts and the scientific community. FE does not, strictly speaking, follow an analytical method. This could explain why, to make up for a lack of appropriate quality reference, a specific documentation was drafted and written by the staff of the Department of Forensic Entomology in order to define working methods complying with quality standards (testing methods). A quality assurance system is laborious to set up and maintain and can be perceived as complex, time-consuming and never-ending. However, a survey performed in 2011 revealed that the accreditation process in the frame of expertise work has led to new well-defined working habits, based on an effort at transparency. It also requires constant questioning and a proactive approach, both profitable for customers (magistrates, investigators) and analysts (forensic entomologists).

  14. The New Microbiology: a conference at the Institut de France.

    PubMed

    Radoshevich, Lilliana; Bierne, Hélène; Ribet, David; Cossart, Pascale

    2012-08-01

    In May 2012, three European Academies held a conference on the present and future of microbiology. The conference, entitled "The New Microbiology", was a joint effort of the French Académie des sciences, of the German National Academy of Sciences Leopoldina and of the British Royal Society. The organizers - Pascale Cossart and Philippe Sansonetti from the "Académie des sciences", David Holden and Richard Moxon from the "Royal Society", and Jörg Hacker and Jürgen Hesseman from the "Leopoldina Nationale Akademie der Wissenschaften" - wanted to highlight the current renaissance in the field of microbiology mostly due to the advent of technological developments and allowing for single-cell analysis, rapid and inexpensive genome-wide comparisons, sophisticated microscopy and quantitative large-scale studies of RNA regulation and proteomics. The conference took place in the historical Palais de l'Institut de France in Paris with the strong support of Jean-François Bach, Secrétaire Perpétuel of the Académie des sciences.

  15. Lignes directrices pour le suivi des cardiostimulateurs au canada : consensus du groupe de travail canadien sur la cardiostimulation

    PubMed

    D Fraser JD; M Gillis AM; Irwin; Nishimura; Tyers; Philippon

    2000-03-01

    Un sondage sur les pratiques de cardiostimulation au Canada effectue en 1997 a revele un profond desir pour des lignes directrices nationales sur le suivi des cardiostimulateurs. Ces lignes directrices sur le suivi des cardiostimulateurs representent une declaration de consensus du Groupe de travail canadien sur la cardiostimulation. Le suivi des patients en personne plutot que par moyens transtelephoniques est preferable. Les patients devraient etre examines au minimum dans les 72 heures suivant l'implantation, 2 a 12 semaines et 6 mois apres l'implantation, et annuellement par la suite. Des examens plus frequents peuvent etre requis pour certains patients. Ceci dependra des problemes cardiovasculaires associes et des appareils en particulier. Une visite de suivi typique devrait comprendre un examen cardiovasculaire oriente, l'interrogation du systeme de cardiostimulation et une revue des donnees de telemetrie, un examen du rythme sous-jacent, un examen des seuils de stimulation et de detection et une reprogrammation adequate des parametres pour optimaliser le fonctionnement et la longevite de l'appareil.

  16. Psychosexual development among HIV-positive adolescents in Abidjan, Côte d'Ivoire.

    PubMed

    Aka Dago-Akribi, Hortense; Cacou Adjoua, Marie-Chantal

    2004-05-01

    Some 84,000 children with HIV/AIDS live in Côte d'Ivoire, where very little therapeutic or psychological help is available to them. The Yopougon Child Programme of the "Agence Nationale de Recherche sur le Sida" was launched in Abidjan in October 2000. It provides services for HIV-infected children and psychological consultations for children and their parents. This paper is about the psychosexual development of the HIV-positive adolescents in the Programme, 11 girls and 8 boys aged 13-17, their problems with HIV-related physiological and psychosexual changes, and relationships with their parents. The information was gathered in individual therapy sessions, group discussions and family support sessions. Bodily development was of major importance to these adolescents, particularly among those who had not yet developed secondary sexual characteristics and were shorter and weighed less than their peers. Those who had not achieved puberty were unable to participate in traditional rituals and worried whether they could ever marry or have children. In most cases, adolescents with HIV have been infected by a sexually transmitted virus without having had sexual relations themselves. They need support dealing with their sexual development and sexual feelings, along with medical care, in a context in which HIV infection is a secret, impossible to talk about with their peers.

  17. OSCAR statement of methods

    NASA Astrophysics Data System (ADS)

    Massat, Jean-Pierre; Balmes, Etienne; Bianchi, Jean-Philippe; Van Kalsbeek, Guido

    2015-03-01

    OSCAR (Outil de Simulation du CAptage pour la Reconnaissance des défauts) is the pantograph-catenary dynamic software developed by Société Nationale des Chemins de fer Français (SNCF) since 2004. A three-dimensional finite element (FE) mesh allows the modelling of any catenary type: alternating current (AC) or direct current (DC) designs, and conventional or high-speed lines. It is a representative of the real overhead line geometry, with contact wire (CW) irregularities, staggered alignment of the CW, dropper spacing, wire tension, etc. Nonlinearities, such as slackening of droppers and unilateral contact between the pantograph and the CW, are taken into account. Several pantograph models can be used, with a complexity level growing from the three-lumped-mass model to the multibody model. In the second case, a cosimulation between the FE method catenary and the multibody pantograph models has been developed. Industrial features for pre- and post-treatments were developed to increase robustness of results and optimise computation time. Recent developments include volume meshing of the CW for stress computation or statistical analysis and lead to new fields of studies such as fatigue failure or design optimisation. OSCAR was fully validated against in-line measurements for its different AC and DC catenary models as well as its different pantograph models (with independent strips for instance) and has continuously been certified against EN50318 since 2008.

  18. Lagrangian statistics in turbulent channel flow: implications for Lagrangian stochastic models

    NASA Astrophysics Data System (ADS)

    Stelzenmuller, Nickolas; Polanco, Juan Igancio; Vinkovic, Ivana; Mordant, Nicolas

    2016-11-01

    Lagrangian acceleration and velocity correlations in statistically one-dimesional turbulence are presented in the context of the development of Lagrangian stochastic models of inhomogeneous turbulent flows. These correlations are measured experimentally by 3D PTV in a high aspect ratio water channel at Reτ = 1450 , and numerically from DNS performed at the same Reynolds number. Lagrangian timescales, key components of Lagrangian stochastic models, are extracted from acceleration and velocity autocorrelations. The evolution of these timescales as a function of distance to the wall is presented, and compared to similar quantities measured in homogeneous isotropic turbulence. A strong dependance of all Lagrangian timescales on wall distance is present across the width of the channel. Significant cross-correlations are observed between the streamwise and wall-normal components of both acceleration and velocity. Lagrangian stochastic models of this flow must therefore retain dependance on the wall-normal coordinate and the components of acceleration and velocity, resulting in significantly more complex models than those used for homogeneous isotropic turbulence. We gratefully acknowledge funding from the Agence Nationale de la Recherche, LabEx Tec 21, and CONICYT Becas Chile.

  19. Effect of the band structure in a rigorous two-body model with long-range interactions in 1D optical lattices

    NASA Astrophysics Data System (ADS)

    Kristensen, Tom; Simoni, Andrea; Launay, Jean-Michel

    2016-05-01

    We compute scattering and bound state properties for two ultracold molecules in a pure 1D optical lattice. We introduce reference functions with complex quasi-momentum that naturally account for the effect of excited energy bands. Our exact results for a short-range interaction are first compared with the simplest version of the standard Bose-Hubbard (BH) model. Such comparison allows us to highlight the effect of the excited bands, of the non-on-site interaction and of tunneling with distant neighbor, that are not taken into account in the BH model. The effective interaction can depend strongly on the particle quasi-momenta and can present a resonant behavior even in a deep lattice. As a second step, we study scattering of two polar particles in the optical lattice. Peculiar Wigner threshold laws stem from the interplay of the long range dipolar interaction and the presence of the energy bands. We finally assess the validity of an extended Bose-Hubbard model for dipolar gases based on our exact two-body calculations. This work was supported by the Agence Nationale de la Recherche (Contract No. ANR-12-BS04-0020-01).

  20. Proposal for laser cooling of rare-earth ions

    NASA Astrophysics Data System (ADS)

    Dulieu, Olivier; Hong, Ye; Wyart, Jean-François; Lepers, Maxence

    2016-05-01

    The efficiency of laser cooling relies on the existence of an almost closed optical-transition cycle in the energy spectrum of the considered species. In this respect, rare-earth elements exhibit many transitions which are likely to induce noticeable leaks from the cooling cycle. In this work, to determine whether laser cooling of singly ionized erbium Er+ is feasible, we have performed accurate electronic-structure calculations of energies and spontaneous-emission Einstein coefficients of Er+, using a combination of ab initio and least-squares-fitting techniques. We identify five weak closed transitions suitable for laser cooling, the broadest of which is in the kilohertz range. For the strongest transitions, by simulating the cascade dynamics of spontaneous emission, we show that repumping is necessary, and we discuss possible repumping schemes.We expect our detailed study on Er+ to give good insight into the laser cooling of neighboring ions such as Dy+. Supported by ``Agence Nationale de la Recherche'' (ANR), under the project COPOMOL (Contract No. ANR-13-IS04-0004-01).

  1. Exchange and correlation effects on the superconducting transition of two-dimensional multivalley semiconductors

    NASA Astrophysics Data System (ADS)

    Pamuk, Betul; Baima, Jacopo; Dovesi, Roberto; Calandra, Matteo; Mauri, Francesco

    It has recently been shown that the enhancement in the superconducting temperature of two-dimensional semiconductors at low doping is linked to the electron-electron interaction enhancing the response to the valley polarization that is due to the electron-phonon coupling. In this work, we extend this study to analyze the exchange and correlation effects on the electronic, magnetic, and vibrational properties of Li-doped ZrNCl and HfNCl - typical examples of two-dimensional two-valley semiconductors. We show that these properties can be calculated by ab initio density functional theory only by using approximations beyond the generalized gradient approximation. Finally, we present the link between the enhancement of the spin susceptibility and superconducting temperature by demonstrating that the electron-phonon coupling is acting as a pseudo-magnetic field causing the valley polarization. This work is supported by the Graphene Flagship and by Agence Nationale de la Recherche under reference ANR-13-IS10-0003-01.

  2. Circular flow patterns induced by ciliary activity in reconstituted human bronchial epithelium

    NASA Astrophysics Data System (ADS)

    Viallat, Annie; Khelloufi, Kamel; Gras, Delphine; Chanez, Pascal; Aix Marseille Univ., CNRS, CINaM, Marseille, France Team; Aix Marseille Univ., CNRS, Inserm, LAI, Marseille, France Team

    2016-11-01

    Mucociliary clearance is the transport at the surface of airways of a complex fluid layer, the mucus, moved by the beats of microscopic cilia present on epithelial ciliated cells. We explored the coupling between the spatial organisation and the activity of cilia and the transport of surface fluids on reconstituted cultures of human bronchial epithelium at air-liquid interface, obtained by human biopsies. We reveal the existence of stable local circular surface flow patterns of mucus or Newtonian fluid at the epithelium surface. We find a power law over more than 3 orders of magnitude showing that the average ciliated cell density controls the size of these flow patterns, and, therefore the distance over which mucus can be transported. We show that these circular flow patterns result from the radial linear increase of the local propelling forces (due to ciliary beats) on each flow domain. This linear increase of local forces is induced by a fine self-regulation of both cilia density and orientation of ciliary beats. Local flow domains grow and merge during ciliogenesis to provide macroscopic mucus transport. This is possible only when the viscoelastic mucus continuously exerts a shear stress on beating cilia, revealing a mechanosensitive function of cilia. M. K. Khelloufi thanks the society MedBioMed for financial support. This work was supported by the ANR MUCOCIL project, Grant ANR-13-BSV5-0015 of the French Agence Nationale de la Recherche.

  3. [Molecular biology methods in immunohematology].

    PubMed

    Tournamille, C

    2013-05-01

    The molecular basis of almost all antigens of the 33 blood group systems are known. These knowledge and the advent of the PCR technology have allowed the DNA-based genotyping in order to predict the presence or absence of a blood group antigen on the cell membrane of red blood cells. DNA genotyping is required in cases where red blood cells patient cannot be used for serological typing either after a recent transfusion or because of the presence of autoantibodies on the red blood cells. Numerous DNA assays are available to detect any nucleotide polymorphism on the genes encoding blood group antigens. The technologies have improved to answer quickly to any case of transfusion emergency and to limit the risk of DNA contamination in a molecular diagnostic laboratory. Some technologies are ready for high-throughput blood group genotyping. They will be used in the future to obtain a fully typed blood group card of each donor but also to detect blood donors with rare phenotypes to register them to the Banque Nationale de Sang de Phénotype Rare (BNSPR).

  4. The PEGASES gridded ion-ion thruster physics, performance and predictions

    NASA Astrophysics Data System (ADS)

    Aanesland, Ane; Rafalskyi, Dmytro; Bredin, Jerome; Grondein, Pascaline; Oudini, Noureddine; Chabert, Pascal

    2013-09-01

    The PEGASES (Plasma propulsion with Electronegative gases) thruster is a gridded ion thruster that accelerates alternately positively and negatively charged ions to provide thrust. Over the last years various prototypes have been tested, adequate diagnostics have been developed and analytical models and simulations are made to better understand and control the physics involved. The plasma density in the region of the ion-ion plasma predicts that the performance of the PEGASES thruster can be comparable to existing thrusters on the market. We have recently provided the first experimental proof-of-concept, accelerating alternately positive and negative ions from an ion-ion plasma within a 10 kHz cycle. Here we present the state of the art in the PEGASES development and discuss the various physics involved and its possible future in space. This work is funded by EADS Astrium, ANR (Agence nationale de la recherche) under contract ANR-11-BS09-040 and FP7 under contract PIIF-GA-2012-326054.

  5. Local responses to French medical imperialism in late nineteenth-century Algeria.

    PubMed

    Gallois, William

    2007-08-01

    This article offers the first account of the lives of Algerian-born doctors working in the French colonial medical service between 1870 and 1900. Their stories reveal the manner in which the idea of medical imperialism had collapsed in Algeria, as a result of maladministration, racial policies, competition between civil and military authorities, budgetary constraints and the rise of the colons. The article also indicates the way in which medicine became a locus of opposition to French rule. It shows how the first decades of the Third Republic were critical in terms of a shift from the earlier idea of medicine serving as an emblem of the mission civilisatrice to the ideological potential of medicine being seen in much more nuanced terms by both French settlers and Algerian locals. It is argued that the notion of cultural resistance to imperialism through medicine emerges in the 1870s and 1880s, thereby prefiguring the work of Fanon and the Front de Liberation Nationale's later analysis of the 'sickness' of colonial Algerian society.

  6. Radioactive waste management in France and international cooperation

    SciTech Connect

    Marque, Y. )

    1991-01-01

    Long-term industrial management of radioactive waste in France is carried out by the Agence Nationale pour la gestion des Dechets Radioactifs. (ANDRA), which is a public body responsible mainly for siting, design, construction, and operation of the disposal facilities for every kind of radioactive waste produced in the country. Furthermore, ANDRA has to define and control the required quality of waste packages delivered for disposal. As far as disposal is concerned, it is customary in France to classify waste in two main categories. The first category includes all the so-called short-lived low-level waste (LLW) containing mainly radioactive substances have < 30-yr half-lives (beta-gamma emitters) and, in a few cases, a very small amount of long-half-life substances. The second category includes waste that contains a significant amount of long-lived substances such as transuranic nuclides. Throughout the world, public acceptance is at present the main issue in the siting of a disposal facility. Development of international cooperation is desirable in order to present a consistent international policy, whatever technical options may be chosen according to local considerations and possibilities. It can also be very fruitful to have bilateral collaboration where approaches in the two countries seem to be similar. International cooperation is already a matter of fact within the framework of international organizations such as the International Atomic Energy Agency, the Organization for Economic Cooperation and Development, and the Commission of European Communities.

  7. Technical and design update in the AUBE French low-level radioactive waste disposal facility

    SciTech Connect

    Marque, Y.

    1989-01-01

    Long-term industrial management of radioactive waste in France is carried out by the Agence Nationale pour la Gestion des Dechets Radioactifs (ANDRA). ANDRA is in charge of design, siting, construction, and operation of disposal centers. The solution selected in France for the disposal of low- and medium-level, short-lived radioactive waste is near-surface disposal in the earth using the principle of multiple barriers, in accordance with national safety rules and regulations, and based on operating experience from the Centre de Stockage de la Manche. Since the center's start-up in 1969, 400,000 m{sup 3} of waste have been disposed of. The French national program for waste management is proceeding with the construction of a second near-surface disposal, which is expected to be operational in 1991. It is located in the department of AUBE (from which its name derives), 100 miles southeast of Paris. The paper describes the criteria for siting and design of the AUBE disposal facility, design of the AUBE facility disposal module, and comparison with North Carolina and Pennsylvania disposal facility designs.

  8. Layering from anticyclonic vortices in a rotating stratified medium with combined salinity and temperature effects

    NASA Astrophysics Data System (ADS)

    Sommeria, Joel; Burin, Michael; Viboud, Samuel

    2015-11-01

    We generate anticyclonic vortices by a fluid source in a rotating and uniformly stratified medium, a laboratory model of long lived vortex lenses in the ocean. Experiments are performed in the large `Coriolis' rotating platform at Grenoble, 13 m in diameter, providing previously unaccessible turbulent regimes. The other novelty is to combine temperature and salinity effects, like in `meddies', vortices formed by intrusion in the Atlantic ocean of warm and salty water from the Mediterranean Sea. For both heated an unheated cases, we observe shear driven instability at the vortex periphery, leading to the emission of material filament from a large-scale m=2 instability. Heated vortices behave much the same way but with two key additions. One, prominent at early times, is that the vortex edge appears serrated around most of its circumference in the upper part of the lens. Two, clearer for later times, a staircase density profile develops above the eddy. We explain this small scale turbulence as thermal convection in the statically unstable density profile resulting from selective vertical diffusion of temperature (while salinity is less diffusive). The resulting turbulent mixing generates horizontal intrusions at the upper part of the vortex, unlike the double-diffusive instability. This work has been funded by Agence Nationale de la Recherche (ANR), project `OLA'.

  9. [Required procedure for nominal data files processing in biomedical research].

    PubMed

    Chambon-Savanovitch, C; Dubray, C; Albuisson, E; Sauvant, M P

    2001-12-01

    To date, biomedical research using nominal data files for the data collection, data acquisition or data processing has had to comply with 2 French laws (Law of December, 20, 1988, modified, relating to the protection of patients participating in biomedical research, and the Law of January, 6, 1978, completed by the Law of July 1, 1994 n degrees 94-548, chapter V bis). This later law dictates rules not only for the establishment of nominal data files, but also confer individual rights to filed persons. These regulations concern epidemiological research, clinical trials, drug watch studies and economic health research. In this note, we describe the obligations and specific general and simplified procedure required for conducting biomedical research. Included in the requirements are an information and authorization procedure with the local and national consultative committees on data processing in biomedical research (CCTIRS, Comité Consultatif sur le Traitement de l'Information en Recherche Biomédicale, and CNIL, Commission Nationale Informatique et Libertés).

  10. Excited-state spectroscopy for producing ultracold ground-state NaRb molecule

    NASA Astrophysics Data System (ADS)

    Wang, Dajun; Zhu, Bing; Guo, Mingyang; Li, Xiaoke; Lu, Bo; Wang, Fudong; Ye, Xin; Vexiau, Romain; Luc, Eliane; Bouloufa-Maafa, Nadia; Dulieu, Olivier

    2015-05-01

    We report a joint experimental and theoretical investigation on the excited states of NaRb molecule. In particular, we focus on the A1Σ+ /b3 Π admixture which is a promising intermediate state for transferring weakly-bound NaRb Feshbach molecules to the v = 0 level of the X1Σ+ state. Based on RKR potentials obtained from conventional molecular spectroscopy [1], we identified several levels which satisfy the requirements for efficient two-photon population transfer. Starting from a pure sample of NaRb Feshbach molecules, we have experimentally observed most of these levels. The detailed characterization of these levels, including their transition strengths and singlet/triplet mixing ratios, as well as searching of the v = 0 level of the X1Σ+ state with two-photon Autler-Townes spectroscopy, are well underway. This work is jointly supported by Agence Nationale de la Recherche (#ANR-13-IS04-0004-01) and Hong Kong Research Grant Council (#A-CUHK403/13) through the COPOMOL project.

  11. Highlights of recent studies and future plans for the French human biomonitoring (HBM) programme.

    PubMed

    Fréry, Nadine; Vandentorren, Stéphanie; Etchevers, Anne; Fillol, Clémence

    2012-02-01

    This manuscript presents highlights of recent studies and perspectives from the French human biomonitoring (HBM) programme. Until recently, HBM studies focused on specific populations or pollutants to gain a better understanding of exposure to environmental chemicals, to help regulators reduce environmental exposure and to monitor existing policies on specific concerns. Highlights of recent multicentre biomonitoring studies with specific population or pollutant focus are given. These French HBM studies have been implemented to know: (1) the influence of living near an incinerator on serum dioxin and polychlorinated biphenyl (PCB) levels, (2) the influence of consuming river fish contaminated by PCBs on serum PCBs of fishermen, and (3) the evolution of blood lead levels in children from 1 to 6 years old since 1995. Special emphasis is placed on the use of an integrated (HBM coupled with nutrition and health studies), multipollutant approach. This approach has been initiated in France with a recent national population-based biomonitoring survey, the Etude Nationale Nutrition Santé (ENNS; French Nutrition and Health Survey). This survey will provide the first reference distribution for 42 biomarkers in the French population. The current national HBM strategy will build upon the ENNS and include a national survey of people aged between 6 and 74 years complemented for the neonatal period and childhood by the Etude Longitudinale Française depuis l'Enfance (ELFE; French longitudinal study of children). France also contributes to the harmonization of HBM activities in Europe through participation in European HBM projects.

  12. 234U/238U Disequilibrium along stylolitic discontinuities in deep Mesozoic limestone formations of the Eastern Paris basin: evidence for discrete uranium mobility over the last 1-2 million years

    NASA Astrophysics Data System (ADS)

    Deschamps, P.; Hillaire-Marcel, C. E.; Michelot, J.-L.; Doucelance, R.; Ghaleb, B.; Buschaert, S.

    The (234U/238) equilibrium state of borehole core samples from the deep, low-permeability limestone formations surrounding the target argilite layer of the Meuse/Haute-Marne experimental site of the French agency for nuclear waste management -ANDRA- (Agence nationale pour la gestion des déchets radioactifs) was examined to improve understanding of naturally occurring radionuclide behaviour in such geological settings. Highly precise, accurate MC-ICP-MS measurements of the (234U/238U) activity ratio show that limestone samples characterised by pressure dissolution structures (stylolites or dissolution seams) display systematic (234U/238U) disequilibria, while the pristine carbonate samples remain in the secular equilibrium state. The systematic feature is observed throughout the zones marked by pressure dissolution structures: (i) the material within the seams shows a deficit of 234U over 238U ((234U/238U) down to 0.80) and (ii) the surrounding carbonate matrix is characterised by an activity ratio greater than unity (up to 1.05). These results highlight a centimetric-scale uranium remobilisation in the limestone formations along these sub-horizontal seams. Although their nature and modalities are not fully understood, the driving processes responsible for these disequilibria were active during the last 1-2 Ma.

  13. Vigi4Med Scraper: A Framework for Web Forum Structured Data Extraction and Semantic Representation

    PubMed Central

    Audeh, Bissan; Beigbeder, Michel; Zimmermann, Antoine; Jaillon, Philippe; Bousquet, Cédric

    2017-01-01

    The extraction of information from social media is an essential yet complicated step for data analysis in multiple domains. In this paper, we present Vigi4Med Scraper, a generic open source framework for extracting structured data from web forums. Our framework is highly configurable; using a configuration file, the user can freely choose the data to extract from any web forum. The extracted data are anonymized and represented in a semantic structure using Resource Description Framework (RDF) graphs. This representation enables efficient manipulation by data analysis algorithms and allows the collected data to be directly linked to any existing semantic resource. To avoid server overload, an integrated proxy with caching functionality imposes a minimal delay between sequential requests. Vigi4Med Scraper represents the first step of Vigi4Med, a project to detect adverse drug reactions (ADRs) from social networks founded by the French drug safety agency Agence Nationale de Sécurité du Médicament (ANSM). Vigi4Med Scraper has successfully extracted greater than 200 gigabytes of data from the web forums of over 20 different websites. PMID:28122056

  14. Structure in the Dusty Debris around Vega

    NASA Astrophysics Data System (ADS)

    Wilner, D. J.; Holman, M. J.; Kuchner, M. J.; Ho, P. T. P.

    2002-04-01

    We present images of the Vega system obtained with the IRAM Plateau de Bure interferometer at a 1.3 mm wavelength with submillijansky sensitivity and ~2.5" resolution (about 20 AU). These observations clearly detect the stellar photosphere and two dust emission peaks offset from the star by 9.5" and 8.0" to the northeast and southwest, respectively. These offset emission peaks are consistent with the barely resolved structure visible in previous submillimeter images, and they account for a large fraction of the dust emission. The presence of two dust concentrations at the observed locations is plausibly explained by the dynamical influence of an unseen planet of a few Jupiter masses in a highly eccentric orbit that traps dust in principal mean motion resonances. Based on observations carried out with the IRAM Plateau de Bure Interferometer. IRAM is supported by the Instut Nationale des Sciences de L'Univers, CNRS (France), Max-Plank-Gesellschaft (Germany), and Instituto Geográfico Nacional (Spain).

  15. Nutrient profiling can help identify foods of good nutritional quality for their price: a validation study with linear programming.

    PubMed

    Maillot, Matthieu; Ferguson, Elaine L; Drewnowski, Adam; Darmon, Nicole

    2008-06-01

    Nutrient profiling ranks foods based on their nutrient content. They may help identify foods with a good nutritional quality for their price. This hypothesis was tested using diet modeling with linear programming. Analyses were undertaken using food intake data from the nationally representative French INCA (enquête Individuelle et Nationale sur les Consommations Alimentaires) survey and its associated food composition and price database. For each food, a nutrient profile score was defined as the ratio between the previously published nutrient density score (NDS) and the limited nutrient score (LIM); a nutritional quality for price indicator was developed and calculated from the relationship between its NDS:LIM and energy cost (in euro/100 kcal). We developed linear programming models to design diets that fulfilled increasing levels of nutritional constraints at a minimal cost. The median NDS:LIM values of foods selected in modeled diets increased as the levels of nutritional constraints increased (P = 0.005). In addition, the proportion of foods with a good nutritional quality for price indicator was higher (P < 0.0001) among foods selected (81%) than among foods not selected (39%) in modeled diets. This agreement between the linear programming and the nutrient profiling approaches indicates that nutrient profiling can help identify foods of good nutritional quality for their price. Linear programming is a useful tool for testing nutrient profiling systems and validating the concept of nutrient profiling.

  16. Long-term association of food and nutrient intakes with cognitive and functional decline: a 13-year follow-up study of elderly French women.

    PubMed

    Vercambre, Marie-Noël; Boutron-Ruault, Marie-Christine; Ritchie, Karen; Clavel-Chapelon, Françoise; Berr, Claudine

    2009-08-01

    The objective of the present study was to determine the potential long-term impact of dietary habits on age-related decline among 4809 elderly women (born between 1925 and 1930) in the 'Etude Epidémiologique de Femmes de la Mutuelle Générale de l'Education Nationale' (E3N) study, a French epidemiological cohort. In 1993, an extensive diet history self-administered questionnaire was sent to all participants, and in 2006 another questionnaire on instrumental activities of daily living (IADL) and recent cognitive change was sent to a close relative or friend of each woman. Logistic models adjusted for socio-demographic, lifestyle and health factors were performed to evaluate associations between habitual dietary intakes and two outcomes of interest based on the informant response: recent cognitive decline and IADL impairment. Recent cognitive decline was associated with lower intakes of poultry, fish, and animal fats, as well as higher intakes of dairy desserts and ice-cream. IADL impairment was associated with a lower intake of vegetables. The odds of recent cognitive decline increased significantly with decreasing intake of soluble dietary fibre and n-3 fatty acids but with increasing intake of retinol. The odds of IADL impairment increased significantly with decreasing intakes of vitamins B2, B6 and B12. These results are consistent with a possible long-term neuroprotective effect of dietary fibre, n-3 polyunsaturated fats and B-group vitamins, and support dietary intervention to prevent cognitive decline.

  17. The Gutenberg Bibles: analysis of the illuminations and inks using Raman spectroscopy.

    PubMed

    Chaplin, Tracey D; Clark, Robin J H; Jacobs, David; Jensen, Kristian; Smith, Gregory D

    2005-06-01

    The King George III copy of the Gutenberg Bible, held at the British Library, has been analyzed using Raman spectroscopy to determine the palette of pigments used in the illuminations on this work. The palette is found to comprise cinnabar/vermilion, lead tin yellow (type 1), carbon-based black, azurite, malachite, an organo-copper complex (a "verdigris"), calcium carbonate (chalk), gypsum, gold leaf, and basic lead carbonate ("lead white"). This is in agreement with contemporary descriptions of the pigments used for the illuminations. One pigment could not be identified, specifically the organic dark red/purple color used for the foliage. The palette of this copy of the Gutenberg Bible has been compared with those used for six other copies, held at Eton College and Lambeth Palace, England, the Bibliothèque Mazarine and the Bibliothèque nationale de France, and the Staatsbibliothek zu Berlin and the Niedersachsische Staats- und Universitatsbibliothek (SUB) Göttingen, Germany. The palettes are shown to be similar to one another, even though the styles of the primary illuminations differ. The two Gutenberg Bibles held in Germany, printed on vellum, have the more expensive palettes, which include lazurite. The SUB Göttingen copy has the most extensive palette with 16 pigment-related materials having been identified.

  18. FRIPON, the French fireball network

    NASA Astrophysics Data System (ADS)

    Colas, F.; Zanda, B.; Bouley, S.; Vaubaillon, J.; Marmo, C.; Audureau, Y.; Kwon, M. K.; Rault, J. L.; Caminade, S.; Vernazza, P.; Gattacceca, J.; Birlan, M.; Maquet, L.; Egal, A.; Rotaru, M.; Gruson-Daniel, Y.; Birnbaum, C.; Cochard, F.; Thizy, O.

    2015-10-01

    FRIPON (Fireball Recovery and InterPlanetary Observation Network) [4](Colas et al, 2014) was recently founded by ANR (Agence Nationale de la Recherche). Its aim is to connect meteoritical science with asteroidal and cometary science in order to better understand solar system formation and evolution. The main idea is to set up an observation network covering all the French territory to collect a large number of meteorites (one or two per year) with accurate orbits, allowing us to pinpoint possible parent bodies. 100 all-sky cameras will be installed at the end of 2015 forming a dense network with an average distance of 100km between stations. To maximize the accuracy of orbit determination, we will mix our optical data with radar data from the GRAVES beacon received by 25 stations [5](Rault et al, 2015). As both the setting up of the network and the creation of search teams for meteorites will need manpower beyond our small team of professionals, we are developing a citizen science network called Vigie-Ciel [6](Zanda et al, 2015). The public at large will thus be able to simply use our data, participate in search campaigns or even setup their own cameras.

  19. The FRIPON and Vigie-Ciel networks

    NASA Astrophysics Data System (ADS)

    Colas, François; Zanda, Brigitte; Bouley, Sylvain; Vaubaillon, Jérémie; Vernazza, Pierre; Gattacceca, Jérôme; Marmo, Chiara; Audureau, Yoan; Kwon, Min Kyung; Maquet, Lucie; Rault, Jean-Louis; Birlan, Mirel; Egal, Auriane; Rotaru, Monica; Birnbaum, Cyril; Cochard, François; Thizy, Olivier

    2014-02-01

    FRIPON (Fireball Recovery and interplanetary Observation Network) is a French fireball network recently founded by ANR (Agence Nationale de la Recherche). His aim is to connect meteoritical science with asteroidal and cometary sciences in order to better understand the solar system formation and evolution. The main idea is to cover all the French territory in order to collect a large number of meteorites (one or two per year) with an accurate orbit computation allowing us to pinpoint the parent bodies of the meteorites. About 100 allsky cameras will be installed in 2015 to create a dense network with an average distance of 100 km between two stations. In order to maximize the accuracy of orbit determination, we will mix our optical data with radar data from the GRAVES beacon received by 25 stations (Rault, 2014). As the network installation and the creation of the research teams for meteorites need many persons, at least much more than our small team of professionals, we will develop in parallel a participative science network for amateurs called Vigie-Ciel. As FRIPON is an open project, anybody will be able to buy a "FRIPON like" camera to be within the network, using our FreeTure detection software (Audureau, 2014; Kwon, 2014). Vigie-Ciel will also be used by observers using other types of cameras and by teams of meteorite researchers. Finally we will use the public affinity with meteors and meteorites to develop scientific activities to popularize science.

  20. French fireball network FRIPON

    NASA Astrophysics Data System (ADS)

    Colas, F.; Zanda, B.; Vaubaillon, J.; Bouley, S.; Marmo, C.; Audureau, Y.; Kwon, M. K.; Rault, J.-L.; Caminade, S.; Vernazza, P.; Gattacceca, J.; Birlan, M.; Maquet, L.; Egal, A.; Rotaru, M.; Birnbaum, C.; Cochard, F.; Thizy, O.

    2015-01-01

    FRIPON (Fireball Recovery and Interplanetary Observation Network) was recently founded by ANR (Agence Nationale de la Recherche), its aim being to connect meteoritical science with asteroidal and cometary sciences, in order to better understand our solar system formation and evolution. The main idea is to cover all the French territory to collect a large number of meteorites (one or two per year) with an accurate orbit determination, allowing to pinpoint possible parent bodies. 100 all-sky cameras will be installed at the end of 2015, creating a dense network with an average distance of 100 km between the stations. To maximize the accuracy of the orbit determination, we will mix our optical data with radar data from the GRAVES transmitter received by 25 stations (Rault et al., 2015). As the network installation and the creation of research teams for meteorites involves many persons, at least many more than our small team of professionals, we will develop a participative science network for amateurs called Vigie-Ciel (Zanda et al., 2015). It will be possible to simply use our data, participate in research campaigns or even add cameras to the FRIPON network.

  1. [Insurance and preventive medicine].

    PubMed

    Delachaux, A; Stark, E W; von Schroeder, F

    1978-12-01

    Not only do insurance companies have to pay in case of death, injuries or disease, they are also concerned with their prevention. This is particularly true for the "Swiss National Accident Insurance Fund" (Caisse nationale suisse d'assurance en cas d'accidents--(CNA): for them the prevention of work related accidents and occupational diseases is required by law. Preventive activities in this area are very promising. The progress in the sickness insurance programmes for preventive medicine in the general population has, however, not been as successful. To date, the legislation denies payment for preventive medical care. Why is there this difference? In the case of accidents and occupational diseases, the cause of the pathologies are for the most part exogenous and develop in well known and controlled environments. In the case of disease or invalidity in the general population, the factors are in a large part endogenous and therefore very difficult to supervise, as they develop in much more complex and uncontrolled environments. Nevertheless progress has been done in this field as well. At present, some selected scientifically proven preventive examinations could be included in insurance programmes as part of a general plan and with strict quality control of laboratory findings.

  2. Influence of honey bee (Hymenoptera: Apidae) density on the production of canola (Crucifera: Brassicacae).

    PubMed

    Sabbahi, Rachid; De Oliveira, Domingos; Marceau, Jocelyn

    2005-04-01

    Pollination is an essential step in the seed production of canola, Brassica napus L. It is achieved with the assistance of various pollen vectors, but particularly by the honey bee, Apis mellifera L. Although the importance of pollination has been shown for the production of seed crops, the need to introduce bee hives in canola fields during flowering to increase oil seed yield has not yet been proven. With the purpose of showing this, hives of A. mellifera were grouped and placed in various canola fields in the Chaudière-Appalaches and Capitale-Nationale regions (nine fields; three blocks with three treatments; 0, 1.5, and 3 hives per hectare). A cage was used to exclude pollinators and bee visitations were observed in each field. After the harvest, yield analyses were done in relation to the bee density gradient created, by using pod set, number of seeds per plant, and weight of 1000 seeds. Results showed an improvement in seed yield of 46% in the presence of three honey bee hives per hectare, compared with the absence of hives. The introduction of honey bees contributed to production and consequently, these pollinators represented a beneficial and important pollen vector for the optimal yield of canola.

  3. Histopathology and clinical outcome of NF1-associated vs. sporadic malignant peripheral nerve sheath tumors.

    PubMed

    Hagel, Christian; Zils, Ulrich; Peiper, Matthias; Kluwe, Lan; Gotthard, Stefan; Friedrich, Reinhard E; Zurakowski, David; von Deimling, Andreas; Mautner, Victor Felix

    2007-04-01

    The differences in the clinical course and histopathology of sporadic and neurofibromatosis type 1 (NF1)-associated malignant peripheral nerve sheath tumors (MPNST) were investigated retrospectively. The collective comprised 38 NF1 patients and 14 sporadic patients. NF1 patients were significantly younger at diagnosis (p<0.001) and had a significantly shorter survival time than sporadic patients (median survival 17 months vs. 42 months, Breslow p<0.05). The time interval to local recurrence and metastatic spread was also significantly shorter in NF1 patients (9.4 months vs. 30.0 months, p<0.01; 9.1 months vs. 33.2 months, p<0.001, respectively). In patients with the original histopathological data available (22 NF1 patients, 14 sporadic cases), NF1-associated MPNST showed a significantly higher cellularity compared to sporadic tumors (p<0.001) whereas sporadic MPNST featured a significantly higher pleomorphism (p<0.01). Most importantly, while histopathological variables correlated with French Fédération Nationale des Centres de Lutte Contre le Cancer grading in sporadic MPNST, this was not the case for NF1-associated tumors. The differences between NF1-associated and sporadic MPNST in regard to the clinical course and histopathology may reflect some fundamental differences in biology and pathomechanism of the two tumor groups. Our findings indicate the necessity for a separate grading scheme which takes into account the genetic background in NF1 patients.

  4. The mysterious fate of la Bibliothèque de Louis Pasteur (1822-1895).

    PubMed

    Oertling, Sarita B; Marlin, Robert O; Goldman, Armond S

    2014-11-01

    In addition to the holdings at Bibliothèque Nationale de France and Musée du Pasteur Institut à Paris, major parts of la Bibliothèque de Louis Pasteur are in four institutions in the United States - Reynolds Historical Library at the University of Alabama at Birmingham, Alabama; Burndy Library on the History of Science and Technology at Huntington Library in San Marino, California; Harry Ransom Humanities Research Center at University of Texas in Austin, Texas; and Truman G Blocker History of Medicine Collections, The Moody Medical Library, University of Texas Medical Branch, Galveston, Texas. The circuitous paths that led each part of la Bibliothèque de Louis Pasteur to their present locations were traced and the lives of key individuals in medicine, science and the humanities who obtained these valuable documents were recounted. The documents in each institution were discussed and a plan was considered to make them accessible to scholars who wish to further explore the life of Louis Pasteur.

  5. Color, light, and altruistic creation

    NASA Astrophysics Data System (ADS)

    Charnay, Yves

    2002-06-01

    It seems necessary to me to combine a certain technical inventivity with plastic creation, a particular poetry arises from this relation. The sources of inspiration for works, especially works in which color plays a pre-eminent role, do not only come from nature. The fantasy of the creators evolves and changes thanks to discoveries and technological inventions. My work as a painter has made me particularly sensitive to the diversity of the plastic writings in general and to the chromatic writings in particular. (1) Environmental creation imposes a renewal of the means of creation. Conducting experimental works, I study the particularities of light, mainly its incidence on materials (transmission, reflection, colors, textures, etc.) and its mobility. These works are a source of inspiration for my architectural works and nurture my lectures at the Ecole Nationale Superieure des Arts Decoratifs (National College of Decorative Arts). Environmental creation also imposes some qualities on the artist since he, whether he serves a social entity or a person, serves the whole collectivity. Environmental creation has to be envisaged as an altruistic approach.

  6. "Applied science": a phrase in search of a meaning.

    PubMed

    Bud, Robert

    2012-09-01

    The term "applied science," as it came to be popularly used in the 1870s, was a hybrid of three earlier concepts. The phrase "applied science" itself had been coined by Samuel Taylor Coleridge in 1817, translating the German Kantian term "angewandte Wissenschaft." It was popularized through the Encyclopaedia Metropolitana, which was structured on principles inherited from Coleridge and edited by men with sympathetic views. Their concept of empirical as opposed to a priori science was hybridized with an earlier English concept of "practical science" and with "science applied to the arts," adopted from the French. Charles Dupin had favored the latter concept and promoted it in the reconstruction of the Conservatoire Nationale des Arts et Métiers. The process of hybridization took place from the 1850s, in the wake of the Great Exhibition, as a new technocratic government favored scientific education. "Applied science" subsequently was used as the epistemic basis for technical education and the formation of new colleges in the 1870s.

  7. A French-speaking speech-language pathology program in West Africa: transfer of training between Minority and Majority World countries.

    PubMed

    Topouzkhanian, Sylvia; Mijiyawa, Moustafa

    2013-02-01

    In West Africa, as in Majority World countries, people with a communication disability are generally cut-off from the normal development process. A long-term involvement of two partners (Orthophonistes du Monde and Handicap International) allowed the implementation in 2003 of the first speech-language pathology qualifying course in West Africa, within the Ecole Nationale des Auxiliaires Medicaux (ENAM, National School for Medical Auxiliaries) in Lome, Togo. It is a 3-year basic training (after the baccalaureate) in the only academic training centre for medical assistants in Togo. This department has a regional purpose and aims at training French-speaking African students. French speech-language pathology lecturers had to adapt their courses to the local realities they discovered in Togo. It was important to introduce and develop knowledge and skills in the students' system of reference. African speech-language pathologists have to face many challenges: creating an African speech and language therapy, introducing language disorders and their possible cure by means other than traditional therapies, and adapting all the evaluation tests and tools for speech-language pathology to each country, each culture, and each language. Creating an African speech-language pathology profession (according to its own standards) with a real influence in West Africa opens great opportunities for schooling and social and occupational integration of people with communication disabilities.

  8. Farming in childhood, diet in adulthood and asthma history.

    PubMed

    Varraso, R; Oryszczyn, M P; Mathieu, N; Le Moual, N; Boutron-Ruault, M C; Clavel-Chapelon, F; Romieu, I; Kauffmann, F

    2012-01-01

    The decrease in the number of children living on traditional farms in France during early childhood and changes in diet could both play a role in the increase in asthma prevalence over the last decades. This study aimed to assess 1) the association of farming lifestyle in childhood and asthma, and 2) whether diet in adulthood modifies the association between farming lifestyle in childhood and adult-onset asthma. In the French Etude Epidemiologique des Femmes de la Mutuelle Générale de l'Education Nationale (E3N) study (54,018 females; age 43-68 yrs), three indicators of farming lifestyle were defined: one using individual data (having farmer parents) and two using ecological data (born in a rural area and exposure to cattle). All farming lifestyle indicators were related to childhood- (<16 yrs) and adult-onset asthma (OR (95% CI) values for farmer parents were 0.54 (0.42-0.70) and 0.72 (0.62-0.84), respectively), and to diet in adulthood, in particular to high fruit and low wine intakes. The association between farmer parents and adult-onset asthma was not modified by diet in adulthood. Results extend previous observations in younger cohorts on the protective role of contact with livestock and farming lifestyle on asthma, in particular during childhood.

  9. 3D Model of Surfactant Replacement Therapy

    NASA Astrophysics Data System (ADS)

    Grotberg, James; Tai, Cheng-Feng; Filoche, Marcel

    2015-11-01

    Surfactant Replacement Therapy (SRT) involves instillation of a liquid-surfactant mixture directly into the lung airway tree. Though successful in neonatal applications, its use in adults had early success followed by failure. We present the first mathematical model of 3D SRT where a liquid plug propagates through the tree from forced inspiration. In two separate modeling steps, the plug first deposits a coating film on the airway wall which subtracts from its volume, a ``coating cost''. Then the plug splits unevenly at the airway bifurcation due to gravity. The steps are repeated until a plug ruptures or reaches the tree endpoint alveoli/acinus. The model generates 3D images of the resulting acinar distribution and calculates two global indexes, efficiency and homogeneity. Simulating published literature, the earlier successful adult SRT studies show comparatively good index values, while the later failed studies do not. Those unsuccessful studies used smaller dose volumes with higher concentration mixtures, apparently assuming a well mixed compartment. The model shows that adult lungs are not well mixed in SRT due to the coating cost and gravity effects. Returning to the higher dose volume protocols could save many thousands of lives annually in the US. Supported by NIH Grants HL85156, HL84370 and Agence Nationale de la Recherche, ANR no. 2010-BLAN-1119-05.

  10. Illicit material detector based on gas sensors and neural networks

    NASA Astrophysics Data System (ADS)

    Grimaldi, Vincent; Politano, Jean-Luc

    1997-02-01

    In accordance with its missions, le Centre de Recherches et d'Etudes de la Logistique de la Police Nationale francaise (CREL) has been conducting research for the past few years targeted at detecting drugs and explosives. We have focused our approach of the underlying physical and chemical detection principles on solid state gas sensors, in the hope of developing a hand-held drugs and explosives detector. The CREL and Laboratory and Scientific Services Directorate are research partners for this project. Using generic hydrocarbon, industrially available, metal oxide sensors as illicit material detectors, requires usage precautions. Indeed, neither the product's concentrations, nor even the products themselves, belong to the intended usage specifications. Therefore, the CREL is currently investigating two major research topics: controlling the sensor's environment: with environmental control we improve the detection of small product concentration; determining detection thresholds: both drugs and explosives disseminate low gas concentration. We are attempting to quantify the minimal concentration which triggers detection. In the long run, we foresee a computer-based tool likely to detect a target gas in a noisy atmosphere. A neural network is the suitable tool for interpreting the response of heterogeneous sensor matrix. This information processing structure, alongside with proper sensor environment control, will lessen the repercussions of common MOS sensor sensitivity characteristic dispersion.

  11. Experimental results of an iodine plasma in PEGASES gridded thruster

    NASA Astrophysics Data System (ADS)

    Grondein, Pascaline; Aanesland, Ane

    2015-09-01

    In the electric gridded thruster PEGASES, both positive and negative ions are expelled after extraction from an ion-ion plasma. This ion-ion plasma is formed downstream a localized magnetic field placed a few centimeters from the ionization region, trapping and cooling down the electron to allow a better attachment to an electronegative gas. For this thruster concept, iodine has emerged as the most attractive option. Heavy, under diatomic form and therefore good for high thrust, its low ionization threshold and high electronegativity lead to high ion-ion densities and low RF power. After the proof-of-concept of PEGASES using SF6 as propellant, we present here experimental results of an iodine plasma studied inside PEGASES thruster. At solid state at standard temperature and pressure, iodine is heated to sublimate, then injected inside the chamber where the neutral gas is heated and ionized. The whole injection system is heated to avoid deposition on surfaces and a mass flow controller allows a fine control on the neutral gas mass flow. A 3D translation stage inside the vacuum chamber allows volumetric plasma studies using electrostatic probes. The results are also compared with the global model dedicated to iodine as propellant for electric gridded thrusters. This work has been done within the LABEX Plas@par project, and received financial state aid managed by the Agence Nationale de la Recherche, as part of the programme ``Investissements d'avenir.''

  12. [Nursing minimum data sets (NMDS) - a literature review relating to objective and data elements].

    PubMed

    Ranegger, Renate; Ammenwerth, Elske

    2014-12-01

    Hintergrund: Um den prognostizierten Wandel im Pflegebereich begleiten zu können, wird seit langem die Forderung nach einer einheitlichen Datenbasis gestellt, auf deren Grundlage Pflegedaten von Leistungsanbietern transparent abgebildet werden können. In Österreich fehlt bis dato eine Empfehlung, welche Pflegedaten als «Basisdaten» dokumentiert werden müssen, wodurch eine nationale Vergleichbarkeit von Pflegedaten erschwert wird. Internationale Entwicklungen von Nursing Minimum Data Sets (NMDS) weisen darauf hin, dass Pflegedaten adäquat abgebildet werden können. Ziel der vorgestellten systematischen Literaturanalyse ist es, den aktuellen Wissensstand über NMDS zu erheben und eine strukturierte Beschreibung von NMDS zu entwickeln, welche vor allem die erfassten Datenelemente und die zugehörigen Zielsetzungen der NMDS-Verwendung dokumentieren kann. Ergebnisse: Insgesamt wurden 70 Publikationen zum Thema NMDS in die Literaturübersicht eingeschlossen. Die Analyse der vorgestellten acht NMDS ergab sechs zentrale Zielsetzungen und sechs übergeordnete Datenelemente. Zu den identifizierten sechs Zielsetzungen gehören: Beschreibung der Pflegepraxis, Verteilung finanzieller Mittel, Benchmarking, Personaleinsatzplanung, Trendanalysen und Qualitätssicherung. Die identifizierten sechs Datenelemente umfassen betriebliche Daten, demografische Daten, Pflegediagnosen, -interventionen, -ergebnisse (Qualitätsindikatoren) und Pflegeintensität (klinische Daten). Diskussion: Es hat sich gezeigt, dass kein klarer Zusammenhang zwischen den Zielsetzungen und Datenelementen der untersuchten minimalen Pflegedatensätzen vorliegt.

  13. Bacteria dispersion in microchanel containing random obstacles

    NASA Astrophysics Data System (ADS)

    Creppy, Adama; Auradou, Harold; Douarche, Carine; D'Angelo, Veronica; Nguyen, Jacky; Fluide Automatique Et Systemes Thermiques Collaboration; Laboratoire de Physique Du Solide Collaboration; Groupo de Medios Porosos, Fiuba Collaboration

    2016-11-01

    Dispersion of particles in porous media is a classical problem well studied where physical laws are well established and show good agreement with experimental observations. Recently, contrary to what is thought, observations revealed that self-propelled particles under flow, orient their swimming, what is designated by the term of rheotaxis. But less is known about what happen for self-propelled particles under flow in presence of obstacles. For this purpose, we developed a specific experimental setup in order to show the coupling of bacteria E. Coli RP437 strain swimming with the presence of obstacles in the dispersion process. We chose to develop a micro-fluidic device of rectangular section of 0 . 05 μm2 containing obstacles of different sizes(10 - 150 μm) when a bacteria size is about 1 μm . Thanks to the transparency of the flow we can track hundreds of trajectories of bacteria, the analysis of which revealed that their swimming influences the dispersion when the flow velocity is of the order of their swimming velocity (10 μm / s). Agence Nationale de la Recherche.

  14. Spatial organization of cilia tufts governs airways mucus transport: Application to severe asthma

    NASA Astrophysics Data System (ADS)

    Khelloufi, Mustapha Kamel; Gras, Delphine; Chanez, Pascal; Viallat, Annie

    2014-11-01

    We study the coupling between both density and spatial repartition of beating cilia tufts, and the coordinated transport of mucus in an in-vitro epithelial model. We use a fully differentiated model epithelium in air liquid interface (ALI) obtained from endo-bronchial biopsies from healthy subjects and patients with asthma. The asthma phenotype is known to persist in the model. Mucus transport is characterized by the trajectories and velocities of microscopic beads incorporated in the mucus layer. When the beating cilia tufts density is higher than dc = 11/100 × 100 μm2 a spherical spiral coordinated mucus transport is observed over the whole ALI chamber (radius = 6 mm). Below dc, local mucus coordinated transport is observed on small circular domains on the epithelium surface. We reveal that the radii of these domains scale with the beating cilia tufts density with a power 3.7. Surprisingly, this power law is independent on cilia beat frequency, concentration and rheological properties of mucus for healthy subject and patient with asthma. The rotating or linear mucus transport is related to dispersion of the cilia tufts on the epithelium surface. We show that impaired mucus transport observed in severe asthma model epithelia is due to a drastic lack and dysfunction of cilia tufts. The author acknowledges the support of the French Agence Nationale de la Recherche (ANR) under reference ANR-13-BSV5-0015-01.

  15. LNG scene; Qatar's export plans intensify; sale of Columbia's U. S. terminal in doubt

    SciTech Connect

    Not Available

    1992-07-20

    This paper reports that Activity continues to percolate in Qatar's massive liquefied natural gas export program. In the latest development, France's Ste. Nationale Elf Aquitaine and Japan's Sumitomo Corp. agreed to promote development of Qatar's LNG export project based on supergiant North Offshore gas field and step up discussions with potential buyers in coming months. Target markets lie in Japan and the Far East. Among other LNG operations, Columbia Gas System Inc. last week the it was told by Shell LNG Co. it is unlikely that presale conditions will be met prior to Shell LNG's scheduled purchase July 29 of 40.8% of the stock in Columbia LNG. Columbia LNG owns and LNG receiving terminal at Cove Point, Md., with a design sendout capacity of 1 bcfd of regasified LNG. That makes it the biggest in type U.S. Columbia the it had not received work on what action Shell LNG will take on the purchase agreement. However, failure to meet the undisclosed conditions will allow Shell LNG to end the agreement.

  16. Rapport sur l'état du patrimoine astronomique dans les observatoires français de la fin du XIXè siècle

    NASA Astrophysics Data System (ADS)

    Damm, E.; Pécontal, E.

    2012-12-01

    Suite au colloque sur la sauvegarde du patrimoine astronomique organisé par le MAEE et la SAF, sous l'égide de l'UNESCO, qui a conduit à l'adoption de la Déclaration de Paris, les directeurs d'observatoires institutionnels qui étaient absents du colloque ont ressenti le besoin de discuter de ces conclusions prises en leur nom. L'initiative d'organiser une réunion des directeurs des Observatoires des Sciences de l'Univers (OSU) à ce sujet le 30 janvier 2012 a été prise par François Vernotte, directeur de l'Observatoire de Besançon. Le présent compte-rendu de visite résulte d'une initiative spontanée d'Emmanuel Pécontal, astronome responsable du Patrimoine à l'observatoire de Lyon, et d'Evelyne Damm, membre de la Commission Nationale de classement des Monuments Historiques (CNMH) et élue à la communauté d'agglomération des Portes de l'Essonne oû est sis l'observatoire de Camille Flammarion.

  17. Cosmic Voids As Standard Rulers For Cosmology

    NASA Astrophysics Data System (ADS)

    Lavaux, Guilhem; Wandelt, B. D.

    2012-01-01

    We show a purely geometrical method for probing the expansion history of the Universe from the observation of the shape of stacked voids in spectroscopic redshift surveys. This method is an Alcock-Pasczynski test based on the average sphericity of voids posited on the local isotropy of the Universe, which acts as rulers of unknown size. We describe the algorithm that we use to detect and stack voids in redshift shells on the light cone. We establish, and test on N-body simulation, a robust statistical model for estimating the average stretching of voids in redshift space. Finally, we discuss the constraining power on dark energy parameters in terms of the figure of merit of the Dark Energy Task Force. We estimate the figure of merit for SDSS, BOSS and EUCLID class surveys. For Euclid, the figure of merit is an order of magnitude higher than Baryonic Acoustic Oscillation based methods. We acknowledge financial support from NSF Grant AST 07-08849, AST 09-08693 and from BDW's Chaire d'Excellence granted by the Agence Nationale de Recherche. GL acknowledges support from CITA National Fellowship and financial support from the Government of Canada Post-Doctoral Research Fellowship.

  18. Inverse turbulent cascade in swarming sperm

    NASA Astrophysics Data System (ADS)

    Creppy, Adama; Praud, Olivier; Druart, Xavier; Kohnke, Philippa; Plouraboue, Franck; Inra, Cnrs, Umr, F-37380 Nouzilly, France Team; Université de Toulouse, Inpt, Ups, Imft, Umr 5502, France Team

    2014-11-01

    Collective motion of self-sustained swarming flows has recently provided examples of small scale turbulence arising where viscosity effects are dominant. We report the first observation of an universal inverse enstrophy cascade in concentrated swarming sperm consistent with a body of evidence built from various independent measurements. We found a well-defined k-3 power-law decay of velocity field power-spectrum and relative dispersion of small beads consistent with theoretical predictions in two-dimensional turbulence. Concentrated living sperm displays long-range, correlated whirlpool structures the size of which provides turbulence's integral scale. We propose a consistent explanation for this quasi-two-dimensional turbulence based on self-structured laminated flow forced by steric interaction and alignment, a state of active matter that we call ``swarming liquid crystal.'' We develop scaling arguments consistent with this interpretation. The implication of multi-scale collective dynamics of sperm's collective motility for fertility assessment is discussed. This work has been supported by the French Agence Nationale pour la Recherche (ANR) in the frame of the Contract MOTIMO (ANR-11-MONU-009-01). We thank Pierre Degond, Eric Climent, Laurent Lacaze and Frédéric Moulin for interesting discussions.

  19. Jean Francheteau (1943-2010)

    NASA Astrophysics Data System (ADS)

    Sclater, John; Le Pichon, Xavier

    2010-12-01

    Jean Francheteau, pioneering marine geologist and geophysicist, AGU Fellow, and emeritus professor at the University of Brest (Université de Bretagne Occidentale), died on 21 July in St-Renan, Brittany, France, at the age of 67 after a long illness. With his passing, the field of Earth sciences lost a major contributor to the development of a definitive theory of plate tectonics and one of the first to make visual geological observations on the deep seafloor. Such scientific accomplishments, coupled with his personal charm and the ability to collaborate with researchers from many institutions, ensured that he had a huge influence not only on the world of research but also on teaching and the application of ethics to science. Jean arrived at Scripps Institution of Oceanography in La Jolla, Calif., in 1966 after obtaining a diploma in mining engineering at the prestigious Éole Nationale Supérieure de la Métallurgie et de l'Industrie des Mines in Nancy, France. He chose Victor Vacquier as his thesis supervisor and began working in Vic's lab with John Sclater, ostensibly on heat flow measurements.

  20. [The congress of the French Society of Pharmacology and Therapeutics celebrate in Nancy, 20 April 2016, 40 years of French Regional Pharmacovigilance Centres!].

    PubMed

    Jonville-Béra, Annie-Pierre; Mallaret, Michel; Sgro, Catherine

    2016-09-01

    In 1976, the Regional Pharmacovigilance Centres were created in France to collect and analyze adverse drug reactions. Even if they have, to date, managed and transmitted more than 583,000 adverse drug reactions to the French and international health authorities, the missions of these university hospital structures supervised by clinical pharmacologists are not limited to this activity. They also provide a consulting and diagnostic aid for drug diseases. Their other main mission is information about drugs and their proper use for health professionals and patients on any matter relating to medicines. These queries are used to adjust and focus the training of health professionals in prevention of drug risks and improvement of drug use. Beside signal detection and identification of alerts, the 31 Regional Pharmacovigilance Centres collaborate with the French Drug Agency (Agence nationale de sécurité du medicament et des produits de santé [ANSM]) by achieving expertise on drugs and participation in various working groups and committees. Finally, Regional Pharmacovigilance Centres participate in scientific advancement through research and publication activities.

  1. [Quality standards for medical laboratories].

    PubMed

    Pascal, P; Beyerle, F

    2006-07-01

    In France, medical laboratories must engage a quality approach according to the standard guide de bonne exécution des analyses (GBEA) and, for hospital laboratories, according to the Agence nationale d'évaluation en santé (Anaes). Except the GBEA and the Anaes handbook, which are obligatory standards by regulations, the biologists can choose, for a complementary and voluntary quality process, between the standards ISO 9001, ISO 17025 or ISO 15189. Our aim is to shed light on the advantages of these five standards by realizing a comparative study of their requirements. This work enabled us to highlight a great number of similarities and to raise the characteristics of these five standards. According to their objectives, the biologists will choose a recognition of their quality management system with an ISO 9001 certification or a recognition extended to the technical skills with an ISO 17025 or ISO 15189 accreditation. The contents of these last two documents are rather close and both integrate requirements of the standard ISO 9001. The standard ISO 17025 is, at first sight, rather distant from the biological analysis, requiring many efforts of adaptation, just like the ISO 9001 standard. The standard ISO 15189 seems to be well adapted but more constraining seeing the details requirements level needed. It necessitates a perfect control of the preanalytical phase, which is difficult to acquire in a clinical framework where the biological fluids are not taken by the laboratory staff.

  2. Costless Platform for High Resolution Stereoscopic Images of a High Gothic Facade

    NASA Astrophysics Data System (ADS)

    Héno, R.; Chandelier, L.; Schelstraete, D.

    2012-07-01

    In October 2011, the PPMD specialized master's degree students (Photogrammetry, Positionning and Deformation Measurement) of the French ENSG (IGN's School of Geomatics, the Ecole Nationale des Sciences Géographiques) were asked to come and survey the main facade of the cathedral of Amiens, which is very complex as far as size and decoration are concerned. Although it was first planned to use a lift truck for the image survey, budget considerations and taste for experimentation led the project to other perspectives: images shot from the ground level with a long focal camera will be combined to complementary images shot from what higher galleries are available on the main facade with a wide angle camera fixed on a horizontal 2.5 meter long pole. This heteroclite image survey is being processed by the PPMD master's degree students during this academic year. Among other type of products, 3D point clouds will be calculated on specific parts of the facade with both sources of images. If the proposed device and methodology to get full image coverage of the main facade happen to be fruitful, the image acquisition phase will be completed later by another team. This article focuses on the production of 3D point clouds with wide angle images on the rose of the main facade.

  3. L'Education relative a l'environnement: La representation sociale d'educatrices et d'educateurs

    NASA Astrophysics Data System (ADS)

    Rooney, Elizabeth

    Cette recherche, qui prend appui sur la theorie des representations sociales, a tente de comprendre le phenomene de l'Education relative a l'environnement (ERE) au Quebec. Pour ce faire, j'ai choisi de m'interesser aux points de vue sur le sujet de neuf enseignantes et enseignants d'ecologie oeuvrant dans des ecoles (contexte formel) et de dix animatrices et animateurs oeuvrant dans des centres d'interpretation (contexte non formel). L'analyse narrative de leurs discours recueillis lors d'entrevues individuelles semi-structurees a permis de montrer que la mise en forme et la mise en pratique de l'ERE tendent a s'inscrire dans le prolongement d'une conception essentiellement ecologique de l'environnement et d'une conception plutot mecaniste et sensualiste de l'education, c'est-a-dire comme une simple affaire de transmission de connaissances scientifiques et d'eveil d'acuite sensorielle. Cette analyse a egalement permis de montrer que les educatrices et les educateurs retravaillent ces conceptions pour composer avec les moments et les lieux singuliers de leurs pratiques. Ce faisant, ils innovent et soulevent des questions a propos de la teneur des conceptions ou definitions standardisees de l'ERE. Cette recherche permet ainsi d'eclairer l'aspect a la fois traditionnel et potentiellement innovateur de la representation sociale de l'ERE d'educatrices et d'educateurs de terrain.

  4. A variety of radars designed to explore the hidden structures and properties of the Solar System's planets and bodies

    NASA Astrophysics Data System (ADS)

    Ciarletti, Valérie

    2016-11-01

    Since the very first observations of the Moon from the Earth with radar in 1946, radars are more and more frequently selected to be part of the payload of exploration missions in the Solar System. They are, in fact, able to collect information on the surface structure of bodies or planets hidden by opaque atmospheres, to probe the planet subsurface or even to reveal the internal structure of a small body comet nucleus. A brief review of radars designed for the Solar System planets and bodies' exploration is presented in the paper. This review does not aim at being exhaustive but will focus on the major results obtained. The variety of radars that have been or are currently designed in terms of frequency or operational modes will be highlighted. xml:lang="fr" Une revue non exhaustive des radars scientifiques développés pour l'exploration des planètes et autres corps du système solaire est présentée dans cet article. Quelques résultats majeurs sont présentés. L'accent est mis sur la variété des radars qui ont été et sont actuellement conçus en terme de fréquence ou de mode opératoire en fonction des contraintes de la mission et des objectifs visés.

  5. A Precise Measurement of the Deuteron Elastic Structure Function A(Q2)

    SciTech Connect

    Honegger, Andrian

    1999-12-07

    During summer 1997 experiment 394-018 measured the deuteron tensor polarization in D(e,e'$vec\\{d}$) scattering in Hall C at Jefferson Laboratory. In a momentum transfer range between 0.66 and 1.8 (GeV=c)2, with slight changes in the experimental setup, the collaboration performed six precision measurements of the deuteron structure function A(Q2) in elastic D(e,e'd) scattering . Scattered electrons and recoil deuterons were detected in coincidence in the High Momentum Spectrometer and the recoil polarimeter POLDER, respectively. At every kinematics H(e,e') data were taken to study systematic effects of the measurement. These new precise measurements resolve discrepancies between older data sets and put significant constraints on existing models of the deuteron electromagnetic structure. This work was supported by the Swiss National Science Foundation, the French Centre National de la Recherche Scientifique and the Commissariat 'a l'Energie Atomique, the U.S. Department of Energy and the National Science Foundation and the K.C. Wong Foundation.

  6. Evaluation of optimization of lidar temperature analysis algorithms using simulated data

    NASA Astrophysics Data System (ADS)

    Leblanc, Thierry; McDermid, I. Stuart; Hauchecorne, Alain; Keckhut, Philippe

    1998-03-01

    Temperature lidar data have been simulated in order to test the Jet Propulsion Laboratory (JPL) SO3ANL version 3.2 and Service d'Aeronomie du Centre National de la Recherche Scientifique (CNRS/SA) TEMPER version 2.1 lidar temperature analysis software. Assuming known atmospheric temperature-pressure-density profiles, theoretical raw-photons lidar profiles have been calculated using the actual characteristics of two JPL lidar instruments, located at the Table Mountain Facility (TMF) in California and the Mauna Loa Observatory (MLO), Hawaii, and the CNRS/SA Rayleigh lidar, located at the Observatoire de Haute-Provence (OHP) in France. The simulations were performed for an initial climatological profile taken from the CIRA-86 model and for various profiles derived from this model including realistic atmospheric disturbances. Comparisons between the original and retrieved temperature profiles revealed errors of several kelvins for both the JPL and the CNRS/SA programs. By varying parameters in the simulation, it was possible to determine both the source and the magnitude of these errors. Once identified, the errors were corrected, and the analysis programs were optimized, leading to new operational versions of these programs (SO3ANL version 3.6 and TEMPER version 2.2). An accurate accounting of the temperature lidar analysis errors, before and after this work, is presented.

  7. Meeting IYA Goals for Diverse Planetarium and Science Museum Audiences

    NASA Astrophysics Data System (ADS)

    Nichols, M. M.; Carney, K. E.

    2008-11-01

    The International Year of Astronomy (IYA) in 2009 provides the Adler Planetarium in Chicago, Illinois with a chance to bring astronomy into the city of Chicago and beyond. The Adler serves diverse audiences in the Chicagoland area and elsewhere. Each audience has unique needs to be taken into account when designing for IYA. The Adler has created a suite of programs for IYA that addresses a number of topical strands, tailored for the many audiences that Adler serves. Adler has found synergy between some existing programs designed for these audiences and IYA thematic strands. One advantage of this is that it increases the likelihood of program sustainability. The authors will outline some of Adler's program plans to date from person-to-person community outreach programs such as Café Scientifique programs, to a citizen science light pollution observation program, to programs within the institution, such as a new temporary exhibit about the roles of telescopes in our understanding of the cosmos. The presenters will focus on the range of programming and how they bring together IYA topics as well as addressing the needs of our identified audiences.

  8. International Heliophysical Year: European Activities

    NASA Astrophysics Data System (ADS)

    Briand, C.

    2007-08-01

    The First European General Assembly of the "International Heliophysical Year" (IHY) took place at the headquarters of the Centre Nationial de la Recherche Scientifique (CNRS) in Paris, France, 10-13 January 2006. There were 113 participants representing 27 nations. The science concerned with the International Heliophysical Year programme was first illustrated. Then, the status of current instruments as well as practical information on the campaign management policy was given. Twenty European National Coordinators described the progress of their IHY activities. Representatives from Egypt, Angola and the coordinator of the Balkan, Black and Caspian Sea Region also reported on the progress of IHY activities in their respective regions. People from the IHY Secretariat provided a summary of the global IHY efforts including the United Nations Basic Space Sciences Program. In the education and public outreach front, a variety of activities have been planned: TV and radio shows, board games on space weather, specific programmes for schools and universities, workshops for teachers are some of the actions that were presented by the delegates. Beyond of these national and individual initiatives, specific activities requiring European coordination were discussed. This paper provides an extended summary of the main talks and discussions that held during the meeting.

  9. Astronomy at the University of South Africa

    NASA Astrophysics Data System (ADS)

    Smits, D. P.

    2000-12-01

    Unisa is the largest correspondence university in Africa and the only South African university currently offering a BSc in Astronomy. The astronomy modules can be included in any standard BSc Physics programme. Besides using the radio and optical telescopes at HartRAO and SAAO, Unisa also has its own Observatory on the main campus equipped with modern instrumentation for training students and doing niche research projects. Unisa est la plus importante université d'enseignement par correspondance en Afrique et la seule université d'Afrique du Sud qui forme des licenciés ès sciences (BSc) en Astronomie. Les modules d'astronomie peuvent être inclus dans tout programme standard de Physique pour BSc. En plus d'utiliser les télescopes radio et optiques à HartRAO et SAAO, Unisa a aussi sur le campus principal son propre Observatoire équipé d'une instrumentation moderne pour la formation des étudiants et pour mener à bien des projets de recherche dans des niches scientifiques modernes.

  10. Post-Secondary Students' Relationship to People They Consider to Be Scientific Experts

    NASA Astrophysics Data System (ADS)

    Pouliot, Chantal

    2011-03-01

    This article is situated in contemporary debates about the ways to achieve a scientific literacy that encourages a greater lay participation in public debates and political decision making. Drawing on the notion of "relationship to scientific experts" (in French, "rapport aux experts scientifiques"), I explore the ways in which a group of 3 Quebec post-secondary students describe the relationships they hold toward people whom they consider to be scientific experts, as revealed during a project in which they investigated the controversy surrounding cellular telephone use. To this end, I scrutinize how the members of the group go about describing scientific experts and picture a prospective face-to-face discussion with a scientific expert. The data come from a case study (conducted over a 15-week period). The findings show that the group maintains a relationship of intimidation by scientific experts, in which the latter are depicted in terms of their knowledge and qualifications. Accordingly, the group was overawed not only by the accumulation of knowledge held and produced by scientific experts but also by the latter's research experience and the high social recognition they occasionally enjoyed. Similarly, the group describes a prospective face-to-face discussion with a doctor or a researcher in terms of an impersonal, intimidating encounter during which its members' learning and comprehension in relation to the controversy are assumed to be unequal to the task. The implications of the findings for future research are discussed.

  11. Redistribution of annexin in gravistimulated pea plumules

    NASA Technical Reports Server (NTRS)

    Clark, G. B.; Rafati, D. S.; Bolton, R. J.; Dauwalder, M.; Roux, S. J.

    2000-01-01

    We used immunocytochemistry to investigate the effects of gravistimulation on annexin localization in etiolated pea plumule shoots. In longitudinal sections, an asymmetric annexin immunostaining pattern was observed in a defined group of cells located just basipetal to apical meristems at the main shoot apex and at all of the axillary buds, an area classically referred to as the leaf gap. The pattern was observed using both protein-A-purified anti-annexin and affinity-purified anti-annexin antibodies for the immunostaining. A subset of the cells with the annexin staining also showed an unusually high level of periodic acid Schiff (PAS) staining in their cell walls. Prior to gravistimulation, the highest concentration of annexin was oriented toward the direction of gravity along the apical end of these immunostained cells. In contrast, both at 15 and 30 min after gravistimulation, the annexin immunostain became more evenly distributed all around the cell and more distinctly cell peripheral. The asymmetry along the lower wall of these cells was no longer evident. In accord with current models of annexin action, we interpret the results to indicate that annexin-mediated secretion in the leaf gap area is preferentially toward the apical meristem prior to gravistimulation, and that gravistimulation results in a redirection of this secretion. These data are to our knowledge the first to show a correlation between the vector of gravity and the distribution of annexins in the cells of flowering plants. c 2000 Editions scientifiques et medicales Elsevier SAS.

  12. Chemical composition of semi-regular variable giants. III.

    NASA Astrophysics Data System (ADS)

    Britavskiy, N. E.; Andrievsky, S. M.; Tsymbal, V. V.; Korotin, S. A.; Martin, P.; Andrievska, A. S.

    2012-06-01

    Aims: We derive the stellar atmosphere parameters and chemical element abundances of four stars classified as semi-regular variables of type "d" (SRd). These stars should presumably belong to the Galactic halo population. Methods: Elemental abundances are derived by applying both local thermodynamical equilibrium and non-local thermodynamical equilibrium analyses to high resolution (R ≈ 80 000) spectra obtained with the CFHT ESPaDOnS spectrograph. We determine the abundances of 27 chemical elements in VW Dra, FT Cnc, VV LMi, and MQ Hya. Results: The stars of our present program have a chemical composition that is inconsistent with their presumable status as metal-deficient halo giants. All studied SRd giants have relative-to-solar elemental abundances that are typical of the thick/thin Galactic disk stars. We find that all objects of this class for which spectroscopic follow up analyses have been completed show a dichotomy in the amplitudes of their photometric variations. Specifically, the disk objects have small amplitudes, while halo SRd stars have much larger amplitudes, which indicates that amplitude is obviously related to the metallicity of the star. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.Figures 2 and 3 are available in electronic form at http://www.aanda.org

  13. Chemical composition of semi-regular variable giants. II.

    NASA Astrophysics Data System (ADS)

    Britavskiy, N. E.; Andrievsky, S. M.; Korotin, S. A.; Martin, P.

    2010-09-01

    Aims: The aim of this work was to derive the elemental abundances in four stars classified as semiregular variables of the type “d” (SRd). These stars should presumably belong to the Galactic halo population. Methods: Elemental abundances have been derived from both local thermodynamical equilibrium (LTE) and non-local thermodynamical equilibrium (NLTE) analyses, applied to high-resolution (R ≅ 80 000) spectra obtained with the CFHT ESPaDOnS spectrograph. Results: We have derived the abundances of 29 chemical elements in V463 Her, V894 Her, CW CVn, and MS Hya, and arrived at the following conclusions. Conclusions: The stars of our programme have a chemical composition that does not agree with their presumable status as metal-deficient halo giants. All studied SRd giants have relative-to-solar elemental abundances typical of the thick/thin Galactic disc stars. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  14. Observational survey of the puzzling star HD 179821: Photometric variations and period analysis

    NASA Astrophysics Data System (ADS)

    Le Coroller, H.; Lèbre, A.; Gillet, D.; Chapellier, E.

    2003-03-01

    From new photometric observations (UBVRI), we present the characteristic features of the light variations of the evolved star HD 179821 (= SAO 124414 = IRAS 19114+0002). Our data, collected through 1999 and 2000, have been combined together with previous photometric measurements available in the literature. Thus, a long term V-light curve (gathering more than 10 years of observations for HD 179821) has been composed. We have analysed it with the Fourier transform method. Two main frequencies are present in the resulting power spectrum, reflecting a dominant bimodal pulsator behavior. A long term phenomenon is also found, but it is not possible to decide whether it is periodic. The Fourier analysis has also been applied on two other filters (U and B) and confirms the detected frequencies. On the basis of our period analysis, we discuss the nature of HD 179821: low-mass post-AGB star or high-mass star. based on observations carried out at the Observatoire de Haute Provence, France, operated by the Centre National de la Recherche Scientifique (CNRS).

  15. Lessons learnt from the 15 years experience of the French case in the field of HLLL waste

    SciTech Connect

    Ouzounian, G.

    2007-07-01

    Year 2006 has been marked in France by the vote in the Parliament of the Planning Act of 28 June, 2006, concerning the sustainable management of radioactive materials and waste. This vote was the achievement of a 15 years research programme performed as required by the previous Research Law of 1991, also known as the Bataille Law, from the name of Christian Bataille, MP, who drafted it and monitored its enforcement as a member of the Parliamentary Office for Scientific and Technological Assessment (Office Parlementaire d'Evaluation des Choix Scientifiques et Techniques - OPECST). At that time a stepwise approach to siting was introduced in the process. It included the study of several alternatives to the geological disposal of long lived high level radioactive waste. Those alternatives have been thoroughly studied and assessed before the Government decided to submit the bill to the Parliament. Experience has been gained not only on the scientific and technical aspects, but also in the field of decision making process, also called now governance. However, not only the results of the research programme were decisive in preparing the bill, but also of major importance were the industrial experience of ANDRA and the rigorous programme management along all those years. Main lessons learnt from the experience are given in this paper. (authors)

  16. L'astronomie au féminin

    NASA Astrophysics Data System (ADS)

    Nazé, Yaël

    2006-03-01

    Qui détient le record des découvertes de comètes ? Une femme. Qui a permis de comprendre comment est organisée la population des étoiles ? Une femme. Qui a découvert la loi permettant d'arpenter l'Univers, a trouvé des phares dans l'espace, a compris le fonctionnement des forges stellaires et a bouleversé notre vision de l'Univers ? Encore et toujours une femme... Pourtant, quand on doit citer un astronome -- historique -- au hasard, on pense le plus souvent -- des hommes : Ptolémée, Galilée, Copernic ou, plus près de nous par exemple, Hubble. Certes, au cours des siècles, les femmes n'ont guère eu accès aux sciences en général et -- l'astronomie en particulier mais ce n'est pas une raison pour croire en l'absence totale de contributions dues au beau sexe ! C'est ce que dévoile ici l'auteur. Loin de toute forme de féminisme enragé, on suivra le parcours de quelques scientifiques importantes qui ont par hasard en commun une même particularité : leur sexe.

  17. International Congress on Transposable Elements (ICTE) 2012 in Saint Malo and the sea of TE stories.

    PubMed

    Ainouche, Abdelkader; Bétermier, Mireille; Chandler, Mick; Cordaux, Richard; Cristofari, Gaël; Deragon, Jean-Marc; Lesage, Pascale; Panaud, Olivier; Quesneville, Hadi; Vaury, Chantal; Vieira, Cristina; Vitte, Clémentine

    2012-10-30

    An international conference on Transposable Elements (TEs) was held 21-24 April 2012 in Saint Malo, France. Organized by the French Transposition Community (GDR Elements Génétiques Mobiles et Génomes, CNRS) and the French Society of Genetics (SFG), the conference's goal was to bring together researchers from around the world who study transposition in diverse organisms using multiple experimental approaches. The meeting drew more than 217 attendees and most contributed through poster presentations (117), invited talks and short talks selected from poster abstracts (48 in total). The talks were organized into four scientific sessions, focused on: impact of TEs on genomes, control of transposition, evolution of TEs and mechanisms of transposition. Here, we present highlights from the talks given during the platform sessions. The conference was sponsored by Alliance pour les sciences de la vie et de la santé (Aviesan), Centre national de la recherche scientifique (CNRS), Institut national de la santé et de la recherche médicale (INSERM), Institut de recherche pour le développement (IRD), Institut national de la recherche agronomique (INRA), Université de Perpignan, Université de Rennes 1, Région Bretagne and Mobile DNA. CHAIR OF THE ORGANIZATION COMMITTEE: Jean-Marc Deragon ORGANIZERS: Abdelkader Ainouche, Mireille Bétermier, Mick Chandler, Richard Cordaux, Gaël Cristofari, Jean-Marc Deragon, Pascale Lesage, Didier Mazel, Olivier Panaud, Hadi Quesneville, Chantal Vaury, Cristina Vieira and Clémentine Vitte.

  18. Modelisation et analyse de la reflectance de couverts forestiers de resineux

    NASA Astrophysics Data System (ADS)

    Fournier, Richard A.

    Une analyse de la reflectance de couverts forestiers de resineux constitue l'essentiel de ce projet de recherche. L'objectif pricipal de la demarche scientifique choisie vise a apporter des explications sur l'influence de l'architecture de la foret et des processus d'interaction entre l'eclairement solaire incident et le couvert forestier pour decrire les patrons de reflectance, tel que vue par un capteur numerique. La strategie de recherche s'opere en quatre etapes, c'est-a-dire (1) l'etude des patron radiometriques de couronnes d'arbres, (2) la comprehension du regime de lumiere dans le couvert, (3) la mesure et l'intetgration de l'architecture du couvert de l'echelle regionale jusqu'a la description detaillee de l'arbre et (4) la simulation et la validation des images numeriques a fine resolution spatiale (autour de 50 cm). Ces travaux ont fait ressortir les parametres directeurs pour expliquer la reflectance des couverts forestiers de resineux, donc de fournir une clarification du probleme dans son ensemble.

  19. Sur la nature des absorbeurs dans l'interpretation transactionnelle de la mecanique quantique

    NASA Astrophysics Data System (ADS)

    Boisvert, Jean-Sebastien

    L'interpretation transactionnelle de la mecanique quantique est l'une des plus recentes propositions de description des phenomenes du microcosme. En accord avec les predictions de la mecanique quantique standard, l'interpretation transactionnelle propose une alternative a celle de Copenhague. Son principal avantage est qu'elle permet de visualiser les mecanismes sous-jacents a l'echange d'energie, de quantite de mouvement ou d'autres quantites quantiques entre un emetteur et un absorbeur. Ces echanges sont le resultat, a l'instar de la theorie de l'absorbeur de Wheeler et Feynman, de l'utilisation autant d'ondes avancees que retardees. Bien que l'interpretation transactionnelle n'ait pas attire la plus grande attention scientifique, plusieurs critiques lui ont ete adressees. Dans les annees 1990, differentes experiences a mesure sans interaction ont ete concues. Depuis, il a ete avance que la version originale de l'interpretation transactionnelle pouvait difficilement rendre compte de ce type d'experience et meme qu'elle n'est pas compatible avec le concept d'univers quadridimensionnel. La recherche de ce memoire par article consiste a montrer que lorsque l'on utilise systematiquement l'interpretation transactionnelle en considerant la configuration totale des absorbeurs (incluant l'absorbeur universel), il n'est pas necessaire de faire appel a une hierarchie de transactions comme certains l'ont propose.

  20. Follow-up of a report of a potential linkage for schizophrenia on chromosome 22q12-q13.1: Part 2

    SciTech Connect

    Pulver, A.E.; Lasseter, V.K.; Wolyniec, P.

    1994-03-15

    A collaboration involving four groups of investigators (Johns Hopkins University/Massachusetts Institute of Technology; Medical College of Virginia/The Health Research Board, Dublin; Institute of Psychiatry, London/University of Wales, Cardiff; Centre National de la Recherche Scientifique, Paris) was organized to confirm results suggestive of a schizophrenia susceptibility locus on chromosome 22 identified by the JHU/MIT group after a random search of the genome. Diagnostic, laboratory, and analytical reliability exercises were conducted among the groups to ensure uniformity of procedures. Data from genotyping of 3 dinucleotide repeat polymorphisms (at the loci D22S268, IL2RB, D22S307) for a combined replication sample of 256 families, each having 2 or more affected individuals with DNA, were analysed using a complex autosomal dominant model. This study provided no evidence for linkage or heterogeneity for the region 22q12-q13 under this model. We conclude that if this region confers susceptibility to schizophrenia, it must be in only a small proportion of families. Collaborative efforts to obtain large samples must continue to play an important role in the genetic search for clues to complex psychiatric disorders such as schizophrenia. 32 refs., 3 tabs.

  1. Probability distribution of financial returns in a model of multiplicative Brownian motion with stochastic diffusion coefficient

    NASA Astrophysics Data System (ADS)

    Silva, Antonio

    2005-03-01

    It is well-known that the mathematical theory of Brownian motion was first developed in the Ph. D. thesis of Louis Bachelier for the French stock market before Einstein [1]. In Ref. [2] we studied the so-called Heston model, where the stock-price dynamics is governed by multiplicative Brownian motion with stochastic diffusion coefficient. We solved the corresponding Fokker-Planck equation exactly and found an analytic formula for the time-dependent probability distribution of stock price changes (returns). The formula interpolates between the exponential (tent-shaped) distribution for short time lags and the Gaussian (parabolic) distribution for long time lags. The theoretical formula agrees very well with the actual stock-market data ranging from the Dow-Jones index [2] to individual companies [3], such as Microsoft, Intel, etc. [] [1] Louis Bachelier, ``Th'eorie de la sp'eculation,'' Annales Scientifiques de l''Ecole Normale Sup'erieure, III-17:21-86 (1900).[] [2] A. A. Dragulescu and V. M. Yakovenko, ``Probability distribution of returns in the Heston model with stochastic volatility,'' Quantitative Finance 2, 443--453 (2002); Erratum 3, C15 (2003). [cond-mat/0203046] [] [3] A. C. Silva, R. E. Prange, and V. M. Yakovenko, ``Exponential distribution of financial returns at mesoscopic time lags: a new stylized fact,'' Physica A 344, 227--235 (2004). [cond-mat/0401225

  2. Plasma membrane NADH oxidase of maize roots responds to gravity and imposed centrifugal forces

    NASA Technical Reports Server (NTRS)

    Bacon, E.; Morre, D. J.

    2001-01-01

    NADH oxidase activities measured with excised roots of dark-grown maize (Zea mays) seedlings and with isolated plasma membrane vesicles from roots of dark-grown maize oscillated with a regular period length of 24 min and were inhibited by the synthetic auxin 2,4-dichlorophenoxyacetic [correction of dichorophenoxyacetic] acid. The activities also responded to orientation with respect to gravity and to imposed centrifugal forces. Turning the roots upside down resulted in stimulation of the activity with a lag of about 10 min. Returning the sections to the normal upright position resulted in a return to initial rates. The activity was stimulated reversibly to a maximum of about 2-fold with isolated plasma membrane vesicles, when subjected to centrifugal forces of 25 to 250 x g for 1 to 4 min duration. These findings are the first report of a gravity-responsive enzymatic activity of plant roots inhibited by auxin and potentially related to the gravity-induced growth response. c2001 Editions scientifiques et medicales Elsevier SAS.

  3. L'astronomie dans le monde

    NASA Astrophysics Data System (ADS)

    Manfroid, J.

    2007-09-01

    Anions interstellaires; S Orionis; Altaîr; Courants stellaires; Etoiles jeunes; 2MASSW J1207334-393254; Alpha Andromède; Etoiles à neutrons (1); LH54-425; AGNs invisibles; Deux supernovae; Les GRBs seon Swift; Peser les trous noirs; Formation de trous noirs; Trou noir; ondes gravitationnelles : Virgo entre dans sa phase d'exploitation scientifique; Amas de galaxies actifs; Amas de galaxies; Galaxies actives d'amas; L'univers statique: le retour; Macho; Exoplanètes; Exoplanètes habitables?; Exoplanètes habitables? (suite); Une année d'un an; Une année de 31 heures; Valse des Jupiters; Disque de HD 15115; Impact majeur; Planètes isolées; Super-Jupiter; Impact et mini-extinction; L'effet Pioneer; Toungouska; Spéléo martienne; Autres lunes dactives; Encelade; Hypérion; Pluton dépassé; Satellites d'Uranus; Titan

  4. "De Cassini à l'an 2000": The Paris Observatory Library

    NASA Astrophysics Data System (ADS)

    Vallet, M.; Reymonet, N.

    Paris Observatory founded in 1667 by Louis XIV is one of the so called "Grand Etablissement" under of the aegis of the Ministry of higher education and research, and includes two other centres: Meudon Observatory and the Radioastronomy centre in Nancay, created respectively in 1876 and 1955. The decree which gave birth to the library itself was signed in 1785 by Louis XVI. In 1926 Meudon is joined to Paris. The total number of bound volumes, including journals, is 100.000. This comprises 2000 periodical titles (of which 1200 are current titles), monographs, photographs, incunabula and manuscripts from the 16th to the 20th century, microfilm versions of historical material. The collections of two libraries are complementary. Starting in 1981, the library became part of a national "Centre d'Acquisition et de Diffusion de l'Information Scientifique et Technique" (CADIST) for astronomy and astrophysics documents. The catalogue is available on national networks such as the Pancatalogue or CCN. It may also be accessed on the international OCLC network. Finally the library may be accessed on internet via WWW.

  5. 25th Birthday Cern- Restaurant

    ScienceCinema

    None

    2016-07-12

    Cérémonie du 25ème anniversaire du Cern avec plusieurs orateurs et la présence de nombreux autorités cantonales et communales genevoises et personnalités, directeurs généraux, ministres, chercheurs.... Le conseiller féderal et chef du département des affaires étrangères de la confédération Monsieur Pierre Aubert prend la parole pour célébrer à la fois les résultats très remarquables de la coopération internationale en matière scientifique, mais aussi la volonté politique des états européens de mettre en commun leurs ressources pour faire oeuvre d'avenir. Un grand hommage est aussi donné aux deux directeurs disparus, les prof.Bakker et Gregory.

  6. The 6-9 day wave and rainfall modulation in northern Africa during summer 1981

    NASA Astrophysics Data System (ADS)

    Monkam, David

    2003-09-01

    Zonal and meridional wind components and geopotential height from European Centre for Medium-Range Weather Forecasts model analyses and daily rainfall data from the Institut Français de Recherche Scientifique pour le Développement en Coopération (ORSTOM) are used to study westward propagating 6-9 day waves and rainfall modulation in northern Africa during summer 1981. The 6-9 day wave structure is determined using a composite method. In this structure, there are two vortices of opposite circulation on either side of the latitude 12.5°N. The rainfall maxima are associated with cyclonic vortices and the rainfall minima with anticyclonic vortices, coinciding with the minima and the maxima of geopotential height anomalies, respectively. The composite variability shows that the 6-9 day wave is associated with positive rainfall anomalies in West Africa in the band of latitude 7.5°-17.5°N, in the western part of the area around Senegal and Guinea and in the center toward Lake Chad. The rainfall anomalies are linked to the zonal wind anomalies, and the increase in rainfall is associated with large modulation of the African Easterly Jet zonal wind component, mainly in the cyclonic circulation. The main zones of decreasing rainfall appear north of 17.5°-20°N, toward Sudan, and south of 8°N, near Ivory Coast.

  7. [Charles Gerhardt's life and work].

    PubMed

    Blondel-Mégrelis, Marika

    2008-05-01

    Charles Gerhardt's life and work is rather well-known thanks to Grimaux and Tiffeneau. His reform of the equivalents, his classification, his obtention of organic acid anhydrids and his famous Treatise of Organic Chemistry. His active collaboration to the Revue scientifique et industrielle du Docteur Quesneville, the creation of his Comptes-Rendus des Travaux de Chimie. Are not so often quoted. Thanks to his translations and reviews, German chemical advancements became well known in France Gerhardt was Liebig's translator for almost all his life, even through the fluctuations of their personal relation. He was the representative of German chemistry in France. With Auguste Laurent, with whom he is constantly associated, things need to be examined precisely. Laurent and Gerhardt, friends at a moment, cannot be confounded. Though they worked together for some years, they were not engaged in a similar project. Besides an experimentalist, Laurent was essentially a theorician of chemistry, whereas Gerhardt refused to think about atoms and arrangements. Formulas have to describe relations between facts, in no case anything about arrangements. For posterity however, Gerhardt will be, on the same level as Laurent, the creator of modern chemistry doctrines.

  8. Facility for assessing spectral normal emittance of solid materials at high temperature.

    PubMed

    Mercatelli, Luca; Meucci, Marco; Sani, Elisa

    2015-10-10

    Spectral emittance is a key topic in the study of new compositions, depositions, and mechanical machining of materials for solar absorption and for renewable energies in general. The present work reports on the realization and testing of a new experimental facility for the measurement of directional spectral emittance in the range of 2.5-20 μm. Our setup provides emittance spectral information in a completely controlled environment at medium-high temperatures up to 1200 K. We describe the layout and first tests on the device, comparing the results obtained for hafnium carbide and tantalum diboride ultrarefractory ceramic samples to previous quasi-monochromatic measurements carried out in the PROMES-CNRS (PROcedes, Materiaux et Energie Solaire- Centre National de la Recherche Scientifique, France) solar furnace, obtaining a good agreement. Finally, to assess the reliability of the widely used approach of estimating the spectral emittance from room-temperature reflectance spectrum, we compared the calculation in the 2.5-17 μm spectral range to the experimental high-temperature spectral emittance, obtaining that the spectral trend of calculated and measured curves is similar but the calculated emittance underestimates the measured value.

  9. Micromechanical Study of Metals

    NASA Technical Reports Server (NTRS)

    Velikov, P. A.; Stchapov, N. P.; Lorenz, W. F.

    1945-01-01

    The Institut Scientifique Experimental des Transports at Moscow established toward the end of 1925 had since its inception included in its program the study of the mechanism of plastic deformation and the problems associated with it with reference to the materials of the means of transport. Before the program thus determined upon could be carried out, it was necessary to adopt a method of research, or, more exactly, a system of such methods. Because of the modest equipment of the laboratory of the recently established institute, the choice of any particular method was determined not only by the advantages it offered but also by the resources available. As a result of a series of studies and investigations, a method was determined upon which in this paper will be denoted as the micromechanical method. The underlying basis of this method is already known. As will be seen from the description that follows, the micromechanical method is merely a combination of the micrographic study of plastic deformations with mechanical tests on small specimens. It is a well-known fact that a number of investigators have largely employed and still are employing these two procedures and have thereby obtained good results. The authors of the present paper have found it useful to combine the two methods, by making the two studies simultaneously on the sane specimen.

  10. The Two Central Stars of NGC 1514: Can They Actually Be Related?

    NASA Astrophysics Data System (ADS)

    Méndez, Roberto H.; Kudritzki, Rolf-Peter; Urbaneja, Miguel A.

    2016-10-01

    The central star of the planetary nebula NGC 1514 is among the visually brightest central stars in the sky (V = 9.5). It has long been known to show a composite spectrum, consisting of an A-type star and a much hotter star responsible for the ionization of the surrounding nebula. These two stars have always been assumed to form a binary system. High-resolution spectrograms obtained with Espadons at the Canada-France-Hawaii Telescope on Maunakea have allowed us to measure good radial velocities for both stars: they differ by 13 ± 2 km s-1. The stellar velocities were unchanged after 500 days. We have also estimated the metallicity of the cooler star. Combining these data with other information available in the literature, we conclude that, unless all the published nebular radial velocities are systematically wrong, the cooler star is just a chance alignment, and the two stars are not orbiting each other. The cooler star cannot have played any role in the formation of NGC 1514. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l’Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  11. A streamflow assimilation system for ensemble streamflow forecast over France

    NASA Astrophysics Data System (ADS)

    Thirel, G.; Martin, E.; Mahfouf, J. F.; Massart, S.; Ricci, S.; Habets, F.

    2009-04-01

    SAFRAN-ISBA-MODCOU (SIM) is a hydro-meteorological model used at Météo-France to predict soil water content and river streamflows. In order to produce a better initial state for the Ensemble Streamflow forecasts, an assimilation system is developed at Météo-France. This system uses past streamflow measurements in order to assess the best initial state of soil water content of the model for streamflow prediction. The data assimilation system is developed with a modular software (PALM, from the Centre Européen de Recherche et de Formation Avancée en Calcul Scientifique), and is based on the Best Linear Unbiased Estimator method. Data from a maximum of 186 gauge stations are assimilated over France. This first study focuses on the selection of the best model variables for the assimilation process : root zone layer only or root and sub root layers taken together or apart. Two versions of SIM, including or not an exponential profile of hydraulic conductivity in the soil, are tested, and a set of classical hydrologic scores will be performed in order to describe the performances of the experiments. The impact of this improvement of the initial state of the model on ensemble streamflow forecasts scores will be assessed in a subsequent work.

  12. Autisme et douleur – analyse bibliographique

    PubMed Central

    Dubois, Amandine; Rattaz, Cécile; Pry, René; Baghdadli, Amaria

    2010-01-01

    La présente analyse bibliographique a pour objectif de réaliser un bilan des travaux publiés dans le champ de la douleur et de l’autisme. L’article aborde, dans un premier temps, les études publiées concernant les modes d’expression de la douleur observés dans cette population. Différentes hypothèses permettant d’expliquer les particularités expressives des personnes avec autisme sont ensuite passées en revue : excès d’endorphines, particularités dans le traitement sensoriel, déficit sociocommunicatif. Cette analyse bibliographique aborde, pour terminer, la question de l’évaluation et de la prise en compte de la douleur chez les personnes avec autisme. Les auteurs concluent à l’absence d’homogénéité des résultats des études publiées et au besoin de poursuivre les recherches afin de parvenir à des données consensuelles sur un domaine d’étude encore peu exploité au plan scientifique. Sur un plan clinique, l’approfondissement des connaissances dans ce domaine devrait permettre de mettre au point des outils d’évaluation de la douleur et d’ainsi en assurer une meilleure prise en charge au quotidien. PMID:20808970

  13. Communicating air pollution science to the public and politicians

    NASA Astrophysics Data System (ADS)

    Brimblecombe, P.; Schuepbach, E.

    2006-12-01

    Air pollution of the 21^st century is a problem that involves a large number of chemical species and complex reactions between them. Both the public and politicians finds the science difficult to understand, and so, often mistrust the presentation of data and the scientific principles behind air quality. Yet, there are a range of important issues associated with air pollution that concern lay people and policy makers and hence, they have to be presented in a clear and simple way so that informed judgements can be made. Traditionally, the media was the main way to disseminate scientific discovery, but novel methods for engaging scientists in the transfer of scientific know-how to politicians and the general public have emerged in recent years. Scientists receive relatively little training in the area of communication, and often find engaging in more public debates difficult. These including V.I.P. meetings, Public Open Forum, Café Scientifique and various games and role plays. Such outreach events expose us to new challenges, and the skills required to communicate to non-scientists become an increasingly important part of being a scientist.

  14. Communicating Air Pollution Science to the Public and Politicians

    NASA Astrophysics Data System (ADS)

    Schuepbach, E.; Brimblecombe, P.

    2008-12-01

    Air pollution is a problem that involves a large number of chemical species and complex reactions between them. At the beginning of the 21st century, both, the public and politicians still find the science difficult to understand, and so, often mistrust the presentation of data and the scientific principles behind air quality. Yet, there are a range of important issues associated with air pollution that concern lay people and policy makers. These issues hence have to be presented in a clear and simple way so that informed judgements can be made. Traditionally, the media was the main way to disseminate scientific discovery, but novel methods for engaging scientists in the transfer of scientific know-how to politicians and the general public have emerged in recent years. Scientists receive relatively little training in the area of communication, and often find engaging in more public debates difficult. These including V.I.P. meetings, Public Open Forum, Cafe Scientifique and various games and role plays. Such outreach events expose us to new challenges, and the skills required to communicate to non-scientists become an increasingly important part of being a scientist. Here, we present some examples of evolving best practice in the European Network of Excellence on Atmospheric Composition Change (ACCENT).

  15. Patrick Couvreur: inspiring pharmaceutical innovation.

    PubMed

    Stanwix, Hannah

    2014-05-01

    Patrick Couvreur speaks to Hannah Stanwix, Managing Comissioning Editor: Professor Patrick Couvreur received his pharmacy degree from the Université Catholique de Louvain (Louvain-la-Neuve, Belgium) in 1972. He holds a PhD in pharmaceutical technology from the same university and completed a postdoctoral fellowship at the Eidgenössische Technische Hochschule (Zürich, Switzerland). Since 1984, Professor Couvreur has been Full Professor of Pharmacy at the Paris-Sud University (Paris, France) and was holder of the Chair of Innovation Technologique at the prestigious Collège de France (Paris, France). He has published more than 450 peer-reviewed articles and has an H-index of 73, with over 19,000 citations. Professor Coureur has been recognized by numerous national and international awards, including the 2004 Pharmaceutical Sciences World Congress Award, the prestigious Host Madsen Medal, the Prix Galien, the European Pharmaceutical Scientist Award 2011 from the European Federation of Pharmaceutical Sciences, the Médaille de l'Innovation from the Centre National de la Recherche Scientifique, and recently the European Inventor Award 2013 from the European Patent Office.

  16. The Ethiopian initiative to build sustainable capacity for operational research: overview and lessons learned.

    PubMed

    Klinkenberg, E; Assefa, D; Rusen, I D; Dlodlo, R A; Shimeles, E; Kebede, B; Fiseha, D; Tsegaye, F; Leimane, I; Teklai, Y; Dacombe, R; Aseffa, A

    2014-12-21

    Contexte : La recherche opérationnelle programmatique joue un rôle majeur dans la lutte contre la tuberculose (TB). En 2012, le ministère éthiopien de la santé a lancé une initiative de renforcement des capacités en recherche opérationnelle (OR).Objectif : Développer des capacités pérennes d'OR en Ethiopie dans le cadre d'une initiative s'étalant sur plusieurs années.Schéma : L'initiative a été élaborée en collaboration avec des experts régionaux, nationaux et internationaux. Des équipes représentant les régions d'Ethiopie ont réalisé une OR relative aux priorités nationales et régionales. Un programme de formation de mentors domestiques a été inclus afin d'exploiter l'expertise locale et d'accroitre la pérennité. La capacité existante a été renforcée grâce à un financement compétitif offrant aux chercheurs du domaine de la TB un soutien financier et technique. Le fonctionnement du comité de concertation éthiopien sur la recherche relative à la TB a également bénéficié d'un soutien. Les comités d'éthique régionaux ont été renforcés ou créés lorsqu'ils n'existaient pas.Résultats : Cinquante-deux personnes ont été formées et ont réalisé 13 projets d'OR, dont six ont été publiés à ce jour. De plus, huit protocoles ont été soutenus par des subventions. Les comités d'éthique ont été renforcés dans toutes les régions.Conclusion: L'initiative a formé des participants de toutes les régions et ceux-ci ont terminé avec succès toutes les étapes du processus d'OR. Le succès de ce programme peut être attribué à une approche sous forme de travail d'équipe, à un apprentissage sur le tas, au programme intégré de mentors et à une forte appropriation nationale.

  17. Characteristics of energy intake under-reporting in French adults.

    PubMed

    Berta Vanrullen, Isabelle; Volatier, Jean-Luc; Bertaut, Aurélie; Dufour, Ariane; Dallongeville, Jean

    2014-04-14

    Energy intake under-reporting (UR) is a concern in nutritional epidemiological studies, as it may distort the relationships between dietary habits and health. Although UR is known to be associated with certain characteristics, few studies have investigated them in France. Therefore, the goal of the present study was to assess the prevalence and characteristics of UR in French adults. UR was defined according to Goldberg's classification. A sample of 1567 adults was drawn from the nationally representative French dietary survey (Individuelle Nationale des Consommations Alimentaires 2 2006-7). Food intake (7 d record), dietary habits, socio-economic status, region of residence, sedentary behaviour and weight perception variables were assessed. Multivariate logistic regression was used to investigate the associations between UR and a number of covariates. The overall prevalence of UR was 22.5%, similar in men and women. In both sexes, UR was positively associated with overweight and protein intake and inversely associated with age. In women, UR was associated with eating lunch in the office, poor perception of diet quality and sedentary behaviour and was inversely associated with educational level, residence in the Paris region, cereal product intake and eating lunch in a friend's or family member's home. In men, UR was positively associated with a history of slimming and inversely associated with dairy product intake and eating lunch at a staff canteen. In conclusion, UR is prevalent in French adults and is associated with several different characteristics. It is important to take account of UR when investigating diet-disease associations in adults.

  18. Extraction and anonymity protocol of medical file.

    PubMed Central

    Bouzelat, H.; Quantin, C.; Dusserre, L.

    1996-01-01

    To carry out the epidemiological study of patients suffering from a given cancer, the Department of Medical Informatics (DIM) has to link information coming from different hospitals and medical laboratories in the Burgundy region. Demands from the French department for computerized information security (Commission Nationale de l'Informatique et des Libertés: CNIL), in regard to abiding by the law of January 6, 1978, completed by the law of July 1st, 1994 on nominal data processing in the framework of medical research have to be taken into account. Notably, the CNIL advised to render anonymous patient identities before the extraction of each establishment file. This paper describes a recently implemented protocol, registered with the French department for computerized information security (Service Central de la Sécurité des Systèmes d'information : SCSSI) whose purpose is to render anonymous medical files in view of their extraction. Once rendered anonymous, these files will be exportable so as to be merged with other files and used in a framework of epidemiological studies. Therefore, this protocol uses the Standard Hash Algorithm (SHA) which allows the replacement of identities by their imprints while ensuring a minimal collision rate in order to allow a correct linkage of the different information concerning the same patient. A first evaluation of the extraction and anonymity software with regard to the purpose of an epidemiological survey is described here. In this paper, we also show how it would be possible to implement this system by means of the Internet communication network. PMID:8947681

  19. Asteroid Shapes Are Always Close To Fluid Equilibrium

    NASA Astrophysics Data System (ADS)

    Tanga, Paolo; Comito, C.; Hestroffer, D.; Richardson, D. C.

    2010-10-01

    The simple evidence that asteroid are composed by solid rocks suggests that their shape can be rather far from the theoretical equilibrium for rotating fluid bodies. The possible fragmented ("rubble-pile") nature of most of them has suggested interpretations based on elasto-plastic models (such as the Mohr-Coulomb theory) that take into account the static behavior of a granular structure. However, these approaches did not incorporate explicitly the possible evolution of shapes in time due to external factors such as crater forming impacts or tidal deformations. We revisited the theory of equilibrium shapes for fluids, quantitatively evaluating - by appropriate metrics - the distance of the observed shapes from fluid equilibrium. This distance turns out to be much smaller than previously expected. On the basis of this evidence, we simulated numerically the evolution of gravitational aggregates having a small degree of internal friction, consistent with the theoretical findings. Our results offer a global scenario for the evolution of asteroid shapes under the action of gradual stresses due to minor impacts, tidal forces and seismic shaking. We show that actual asteroid shapes are consistent with the evolution of aggregates tending towards minimum free energy states. We are able to explain the samples of observed shapes obtained by different techniques. Our findings strongly support a highly porous and fragmented nature for most asteroids, at least in an external layer. Reference: Tanga et al. 2009: ApJ Letters, 706, 1, L197-L202 Acknowledgments: PT and CC have been supported by the "Programme Nationale de Planetologie" of France; DCR acknowledges support by the NASA (grant no. NNX08AM39G issued through the Office of Space Science) and by the NSF (grant no. AST0708110).

  20. Comprehensive Chemical Characterisation of Byzantine Glass Weights

    PubMed Central

    Schibille, Nadine; Meek, Andrew; Tobias, Bendeguz; Entwistle, Chris; Avisseau-Broustet, Mathilde; Da Mota, Henrique; Gratuze, Bernard

    2016-01-01

    The understanding of the glass trade in the first millennium CE relies on the characterisation of well-dated compositional groups and the identification of their primary production sites. 275 Byzantine glass weights from the British Museum and the Bibliothèque nationale de France dating to the sixth and seventh century were analysed by LA-ICP-MS. Multivariate statistical and graphical data analysis discriminated between six main primary glass types. Primary glass sources were differentiated based on multi-dimensional comparison of silica-derived elements (MgO, Al2O3, CaO, TiO2, Fe2O3, ZrO2) and components associated with the alkali source (Li2O, B2O3). Along with Egyptian and Levantine origins of the glassmaking sands, variations in the natron source possibly point to the exploitation of two different natron deposits. Differences in strontium to calcium ratios revealed variations in the carbonate fractions in the sand. At least two cobalt sources were employed as colouring agents, one of which shows strong correlations with nickel, indicating a specific post-Roman cobalt source. Typological evidence identified chronological developments in the use of the different glass groups. Throughout the sixth century, Byzantine glass weights were predominately produced from two glasses that are probably of an Egyptian origin (Foy-2 and Foy-2 high Fe). Towards the second half of the sixth century a new but related plant-ash glass type emerged (Magby). Levantine I was likewise found among the late sixth- to early seventh-century samples. The use of different dies for the same batch testifies to large-scale, centralised production of the weights, while the same die used for different primary production groups demonstrates the co-existence of alternative sources of supply. Given the comprehensive design of our study, these results can be extrapolated to the wider early Byzantine glass industry and its changes at large. PMID:27959963

  1. Climatic Trends in Hail Precipitation in France: Spatial, Altitudinal, and Temporal Variability

    PubMed Central

    Hermida, Lucía; Sánchez, José Luis; López, Laura; Berthet, Claude; Dessens, Jean; García-Ortega, Eduardo; Merino, Andrés

    2013-01-01

    Hail precipitation is characterized by enhanced spatial and temporal variability. Association Nationale d'Etude et de Lutte contre les Fléaux Atmosphériques (ANELFA) installed hailpad networks in the Atlantic and Midi-Pyrénées regions of France. Historical data of hail variables from 1990 to 2010 were used to characterize variability. A total of 443 stations with continuous records were chosen to obtain a first approximation of areas most affected by hail. The Cressman method was selected for this purpose. It was possible to find relationships between spatial distributions of the variables, which are supported by obtained Pearson correlations. Monthly and annual trends were examined using the Mann-Kendall test for each of the total affected hailpads. There were 154 pads with a positive trend; most were located between Tarbes and Saint-Gaudens. We found 177 pads with a negative trend, which were largely south of a pine forest in Landes. The remainder of the study area showed an elevated spatial variability with no pattern, even between relatively close hailpads. A similar pattern was found in Lérida (Spain) and Southeast France. In the entire area, monthly trends were predominantly negative in June, July, and August, whereas May had a positive trend; again, however, there was no spatial pattern. There was a high concentration of hailpads with positive trend near the Pyrenees, probably owing to orographic effects, and if we apply cluster analysis with the Mann-Kendall values, the spatial variability is accentuated for stations at higher altitude. PMID:24307872

  2. Dietary and physical activity patterns in French children are related to overweight and socioeconomic status.

    PubMed

    Lioret, Sandrine; Touvier, Mathilde; Lafay, Lionel; Volatier, Jean-Luc; Maire, Bernard

    2008-01-01

    Sedentary behavior (SED) has already been identified as a risk factor of childhood overweight (OW) but less is known about the dietary patterns related to adiposity. Our objective was to investigate if lifestyle patterns combining overall diet and physical activity were associated with childhood OW and if they were involved in the reverse association between socioeconomic status (SES) and OW. Dietary intake was assessed using a 7-d food record in 748 French children aged 3-11 y from the 1998-1999 cross-sectional French Enquête Individuelle et Nationale sur les Consommations Alimentaires national food consumption survey. Weight and height, leisure time physical activity, SED (television viewing), and SES were reported by parents or children by answering questionnaires. Scores for lifestyle patterns were assessed with factor analysis and their relationship with OW was explored by logistic regression analysis. Two similar lifestyle patterns were identified in children aged 3-6 y and 7-11 y: "snacking and sedentary" and "varied food and physically active." The snacking and sedentary pattern was positively associated with OW in the youngest children (P-trend = 0.0161) and partly mediated the negative association of SES to OW. The varied food and physically active pattern was inversely correlated with OW in the eldest children only (P-trend = 0.0401). A third pattern called "big eaters at main meals" was derived in children aged 7-11 y and was positively correlated with OW (P-trend = 0.0165). From a public health perspective, the combinations of identifiable dietary and physical activity behaviors may be useful as a basis for recommendations on preventing OW.

  3. [Restructuring of emergency services: a safety imperative].

    PubMed

    Steg, A

    1994-11-01

    More than 7,000,000 cases have been treated each year in the emergency care units of the french Hospitals. The majority of them have been properly treated. However complaints of unsatisfactory treatment were noted and in some cases very serious complications were reported. The main cause of the weakness of some care units rests in the qualitative and quantitative "under medicalisation". First care is often administered by students without control by the staff. Frequently also, the senior members of these units have an insufficient medical curriculum. A National Commission to reform the emergency care units (Commission Nationale de Restructuration des Urgences on CNRU) has been set up by the Government in order to define ways to reorganize these units. The Commission has established 3 conditions which are required for an emergency care unit: high medical skill which implies that the patients have to be treated by a senior physician; permanent reception: which requires a sufficient number of physicians to allow the presence of seniors 24h/24; responsibility: the function of every member of the team has to be clearly defined. The Commission has suggested the reception of emergency patients to be organised in two structures of different level: 1) the Department of Emergency (Service d'Accueil des Urgences or SAU) in which all the medical and technical requirements allow the reception and treatment of all types of emergency cases; 2) the reception and orientation units (Antennes d'Accueil et d'Orientation or ANACOR) which is a light structure assigned for the patients whose troubles are not surgical and who do not require major treatments. Such an organisation in a double structure requires a clear information of the population, an improvement of the medical regulation of the emergency cases and an the adaptation of the medical studies. Finally the aim of the reform is to improve the quality of care, to increase the safety of patients and to limit the inequality of

  4. Trends in child overweight rates and energy intake in France from 1999 to 2007: relationships with socioeconomic status.

    PubMed

    Lioret, Sandrine; Touvier, M; Dubuisson, C; Dufour, A; Calamassi-Tran, G; Lafay, L; Volatier, J-L; Maire, B

    2009-05-01

    Our objectives were (i) to assess the current prevalence of childhood overweight (including obesity) (OWOB) in France and its relationship with comprehensive socioeconomic status (SES) indicators and (ii) to examine trends in OWOB prevalence and changes in energy intake (EI) and sedentary behavior (SED) based on the previous INCA 1 (Individuelle Nationale des Consommations Alimentaires) data (1998-1999). A representative sample of children aged 3-14 (n = 1,030) was taken from the 2006-2007 cross-sectional INCA 2 food consumption survey. Weight and height were measured. The prevalence of OWOB was estimated according to the IOTF (International Obesity Task Force) definition. Average daily EI was evaluated using a 7-day food record. SED (screen time) and SES were reported by answering questionnaires. SES indicators included the occupation and level of education of the head of the household (HH), and variables describing household wealth. Composite indices of SES were computed by correspondence analysis, and relationships with OWOB were explored by logistic regression analysis. In total, 14.5% (95% CI: 12.1-17.0) of the children were OWOB. All SES indicators were inversely correlated to OWOB. Average EI was equal to 1,739 kcal/day. Daily, children spent 113.5 min watching television, and 38.5 min playing video games or using a computer. Compared to the INCA 1 study, OWOB prevalence was not significantly different, EI was lower, and SED was higher. These trends were the same across all occupational categories of heads of household. Although overall rates of childhood OWOB are currently stabilizing, no change was observed in the strong inverse socioeconomic gradient of OWOB between the two studies.

  5. Satellite remote sensing of hailstorms in France

    NASA Astrophysics Data System (ADS)

    Melcón, Pablo; Merino, Andrés; Sánchez, José Luis; López, Laura; Hermida, Lucía

    2016-12-01

    Hailstorms are meteorological phenomena of great interest to the scientific community, owing to their socioeconomic impact, which is mainly on agricultural production. With its global coverage and high spatial and temporal resolution, satellite remote sensing can contribute to monitoring of such events through the development of appropriate techniques. This paper presents an extensive validation in the south of France of a hail detection tool (HDT) developed for the Middle Ebro Valley (MEV). The HDT is based on consecutive application of two filters, a convection mask (CM) and hail mask (HM), using spectral channels of the Meteosat Second Generation (MSG) satellite. The south of France is an ideal area for studying hailstorms, because there is a robust database of hail falls recorded by an extensive network of hailpads managed by the Association Nationale d'Etude et de Lutte contre les Fleáux Atmosphériques (ANELFA). The results show noticeably poorer performance of the HDT in France relative to that in the MEV, with probability of detection (POD) 60.4% and false alarm rate (FAR) 26.6%. For this reason, a new tool to suit the characteristics of hailstorms in France has been developed. The France Hail Detection Tool (FHDT) was developed using logistic regression from channels of the Spinning Enhanced Visible and Infrared Imager (SEVIRI) sensor of the MSG. The FHDT was validated, resulting in POD 69.3% and FAR 15.4%, thus improving hail detection in the study area as compared with the previous tool. The new tool was tested in a case study with satisfactory results, supporting its future practical application.

  6. Prototype pushing robot for emplacing vitrified waste canisters into horizontal disposal drifts

    SciTech Connect

    Londe, L.; Seidler, W.K.; Bosgiraud, J.M.; Guenin, J.J.; Devaux, P.

    2007-07-01

    Within the French Underground Disposal concept, as described in ANDRA's (Agence Nationale pour la Gestion des Dechets Radioactifs) Dossier 2005, the Pushing Robot is an application envisaged for the emplacement (and the potential retrieval) of 'Vitrified waste packages', also called 'C type packages'. ANDRA has developed a Prototype Pushing Robot within the framework of the ESDRED Project (Engineering Studies and Demonstration of Repository Design) which is co-funded by the European Commission as part of the sixth EURATOM Research and Training Framework Programme (FP6) on nuclear energy (2002 - 2006). The Rationale of the Pushing Robot technology comes from various considerations, including the need for (1) a simple and robust system, capable of moving (and potentially retrieving) on up to 40 metres (m), a 2 tonne C type package (mounted on ceramic sliding runners) inside the carbon steel sleeve constituting the liner (and rock support) of a horizontal disposal cell, (2) small annular clearances between the package and the liner, (3) compactness of the device to be transferred from surface to underground, jointly with the package, inside a shielding cask, and (4) remote controlled operations for the sake of radioprotection. The initial design, based on gripping supports, has been replaced by a 'technical variant' based on inflatable toric jacks. It was then possible, using a test bench, to check that the Pushing Robot worked properly. Steps as high as 7 mm were successfully cleared by a dummy package pushed by the Prototype.. Based on the lessons learned by ANDRA's regarding the Prototype Pushing Robot, a new Scope of Work is being written for the Contract concerning an Industrial Scale Demonstrator. The Industrial Scale Demonstration should be completed by the end of the second Quarter of 2008. (authors)

  7. Algeria: country profile.

    PubMed

    Harding, J

    1987-12-01

    Data are presented on the economy, the people, the population's health, and the culture in this country profile of Algeria. The population numbers 21.7 million. The infant mortality rate, used as a health indicator, is 81/1000 live births. Algeria's gross national product per capita is $2410 (US$15,390). Its main imports are machinery, transport equipment, food, tobacco, and consumer goods. The primary exports include oil, petroleum products, liquified natural gas, wine, and tobacco. Algeria's traditional Berber culture has survived occupation by Phoenicians, Romans, Arabs, and Europeans. The country is made up of an assortment of different social groups and ethnicities, and modern Algeria realized its unitary identity from the anti-colonial struggle. Recent laws allow freedom of association, an indication of growing pluralism in a state where opposition traditionally has been proscribed. 1987 marks the 25th anniversary of Algeria's independence, obtained after a long and bitter war with France. The victory of the Front de Liberation Nationale (FLN) was a signal for French settlers to leave in droves, and much of the country's managerial and technical expertise left with them. Yet, the FLN inherited a sound infrastructure on which to build a modern post-colonial society. Additionally, the country also was to benefit from plentiful hydrocarbon reserves, which guaranteed good foreign exchange earnings. One of the country's goals is to feed itself by investing in a long-neglected agricultural sector, yet presently oil and gas revenues continue to be the driving force behind development. The plans for increasing food production include greater scope for private farmers. A widening gap exists between those who espouse the old values forged by the liberation struggle and a younger generation, for whom the FLN's founding precepts and the leadership's old authoritarian style mean considerably less.

  8. The neutron channeling phenomenon.

    PubMed

    Khanouchi, A; Sabir, A; Boulkheir, M; Ichaoui, R; Ghassoun, J; Jehouani, A

    1997-01-01

    Shields, used for protection against radiation, are often pierced with vacuum channels for passing cables and other instruments for measurements. The neutron transmission through these shields is an unavoidable phenomenon. In this work we study and discuss the effect of channels on neutron transmission through shields. We consider an infinite homogeneous slab, with a fixed thickness (20 lambda, with lambda the mean free path of the neutron in the slab), which contains a vacuum channel. This slab is irradiated with an infinite source of neutrons on the left side and on the other side (right side) many detectors with windows equal to 2 lambda are placed in order to evaluate the neutron transmission probabilities (Khanouchi, A., Aboubekr, A., Ghassoun, J. and Jehouani, A. (1994) Rencontre Nationale des Jeunes Chercheurs en Physique. Casa Blanca Maroc; Khanouchi, A., Sabir, A., Ghassoun, J. and Jehouani, A. (1995) Premier Congré International des Intéractions Rayonnements Matière. Eljadida Maroc). The neutron history within the slab is simulated by the Monte Carlo method (Booth, T. E. and Hendricks, J. S. (1994) Nuclear Technology 5) and using the exponential biasing technique in order to improve the Monte Carlo calculation (Levitt, L. B. (1968) Nuclear Science and Engineering 31, 500-504; Jehouani, A., Ghassoun, J. and Aboubker, A. (1994) In Proceedings of the 6th International Symposium on Radiation Physics, Rabat, Morocco). Then different geometries of the vacuum channel have been studied. For each geometry we have determined the detector response and calculated the neutron transmission probability for different detector positions. This neutron transmission probability presents a peak for the detectors placed in front of the vacuum channel. This study allowed us to clearly identify the neutron channeling phenomenon. One application of our study is to detect vacuum defects in materials.

  9. Dietary intake, physical activity and nutritional status in adults: the French nutrition and health survey (ENNS, 2006-2007).

    PubMed

    Castetbon, Katia; Vernay, Michel; Malon, Aurélie; Salanave, Benoit; Deschamps, Valérie; Roudier, Candice; Oleko, Amivi; Szego, Emmanuelle; Hercberg, Serge

    2009-09-01

    The French National Programme on Nutrition and Health (Programme national nutrition santé (PNNS)), the aim of which is to reduce nutrition-related chronic diseases, necessitates monitoring of nutritional characteristics. Our objective was to describe dietary intake, physical activity and nutritional status in a national sample of adults, especially according to current French recommendations. The study is based on a cross-sectional population-based survey using a multistage sampling design (Etude nationale nutrition santé (ENNS)). Between February 2006 and March 2007, 3115 18-74-year-old adults were included (participation rate 59.7 %). Energy, macronutrient and food consumption were estimated through three randomly distributed 24 h recalls, and compared to PNNS recommendations; physical activity was described using International Physical Activity Questionnaire guidelines; anthropometry, blood pressure and biochemical measurements were assessed according to national and international references. When compared to current recommendations, intake of carbohydrates (>50 % energy intake without alcohol: 26.4 %), SFA ( < 35 % total lipids: 18.5 %) and total fibre (>25 g/d: 13.7 %) was frequently unsatisfactory. While overall consumption of 'meat, seafood and eggs' was satisfactory, that of fruits and vegetables ( > or = 400 g/d: 43.8 %) and seafood (two or more servings per week: 29.9 %) was frequently too low. The physical activity level was satisfactory at 63.2 %. Overweight was observed in 49.3 % of adults, while 30.9 % were hypertensive and 44.1 % had dyslipidaemia. Vitamin and iron-poor status was found to affect less than 10 % of the population. Based on the ENNS survey, overall nutrition remains a problem in France. Comparison of these data with those of other countries could contribute to a better understanding of variations in nutrition-related diseases.

  10. The Mysterious sdO X-ray Binary BD+37°442

    NASA Astrophysics Data System (ADS)

    Heber, U.; Geier, S.; Irrgang, A.; Schneider, D.; Barbu-Barna, I.; Mereghetti, S.; La Palombara, N.

    2014-04-01

    Pulsed X-ray emission in the luminous, helium-rich sdO BD +37°442 has recently been discovered (La Palombara et al. 2012). It was suggested that the sdO star has a neutron star or white dwarf companion with a spin period of 19.2 s. After HD 49798, which has a massive white dwarf companion spinning at 13.2 s in an 1.55 day orbit, this is only the second O-type subdwarf from which X-ray emission has been detected. We report preliminary results of our ongoing campaign to obtain time-resolved high-resolution spectroscopy using the CAFE instrument at Calar Alto observatory and SARG at the Telescopio Nationale Galileo. Atmospheric parameters were derived via a quantitative NLTE spectral analysis. The line fits hint at an unusually large projected rotation velocity. Therefore it seemed likely that BD +37°442 is a binary similar to HD 49798 and that the orbital period is also similar. The level of X-ray emission from BD +37°442 could be explained by accretion from the sdO wind by a neutron star orbiting at a period of less than ten days. Hence, we embarked on radial velocity monitoring in order to derive the binary parameters of the BD+37°442 system and obtained 41 spectra spread out over several month in 2012. Unlike for HD 49798, no radial velocity variations were found and, hence, there is no dynamical evidence for the existence of a compact companion yet. The origin of the pulsed X-ray emission remains as a mystery.

  11. Comprehensive Chemical Characterisation of Byzantine Glass Weights.

    PubMed

    Schibille, Nadine; Meek, Andrew; Tobias, Bendeguz; Entwistle, Chris; Avisseau-Broustet, Mathilde; Da Mota, Henrique; Gratuze, Bernard

    2016-01-01

    The understanding of the glass trade in the first millennium CE relies on the characterisation of well-dated compositional groups and the identification of their primary production sites. 275 Byzantine glass weights from the British Museum and the Bibliothèque nationale de France dating to the sixth and seventh century were analysed by LA-ICP-MS. Multivariate statistical and graphical data analysis discriminated between six main primary glass types. Primary glass sources were differentiated based on multi-dimensional comparison of silica-derived elements (MgO, Al2O3, CaO, TiO2, Fe2O3, ZrO2) and components associated with the alkali source (Li2O, B2O3). Along with Egyptian and Levantine origins of the glassmaking sands, variations in the natron source possibly point to the exploitation of two different natron deposits. Differences in strontium to calcium ratios revealed variations in the carbonate fractions in the sand. At least two cobalt sources were employed as colouring agents, one of which shows strong correlations with nickel, indicating a specific post-Roman cobalt source. Typological evidence identified chronological developments in the use of the different glass groups. Throughout the sixth century, Byzantine glass weights were predominately produced from two glasses that are probably of an Egyptian origin (Foy-2 and Foy-2 high Fe). Towards the second half of the sixth century a new but related plant-ash glass type emerged (Magby). Levantine I was likewise found among the late sixth- to early seventh-century samples. The use of different dies for the same batch testifies to large-scale, centralised production of the weights, while the same die used for different primary production groups demonstrates the co-existence of alternative sources of supply. Given the comprehensive design of our study, these results can be extrapolated to the wider early Byzantine glass industry and its changes at large.

  12. Low prevalence of diabetes mellitus in patients with tuberculosis in Cotonou, Benin.

    PubMed

    Ade, S; Affolabi, D; Agodokpessi, G; Wachinou, P; Faïhun, F; Toundoh, N; Békou, W; Makpenon, A; Ade, G; Anagonou, S; Harries, A D

    2015-06-21

    Cadre : Les trois Centres de Dépistage et de Traitement de la Tuberculose (TB) de Cotonou, Bénin.Objectif : Déterminer la prévalence du diabète sucré (DM) parmi les patients tuberculeux à Cotonou.Méthode : Etude transversale avec enrôlement successif de tous les patients tuberculeux traités depuis au moins 2 semaines entre juin et juillet 2014, et mesure de leur glycémie à jeun. Le diagnostic de DM était retenu sur la base d'une glycémie veineuse à jeun ⩾ 7 mmol/l ou d'un antécédent de DM rapporté par le patient.Résultat : Au total, 159 patients étaient inclus : 114 nouveaux cas de TB pulmonaire à microscopie positive, 5 nouveaux cas de TB pulmonaire à microscopie négative, 8 cas de TB extrapulmonaire, 21 cas de retraitement à germes sensibles et 11 cas de TB multirésistante. D'eux, respectivement 31 (19%), 18 (11%) et 10 (6%) étaient co-infectés, fumeurs et hypertendus. Il y avait huit patients (5%) intolérants au glucose et trois (1.9%) diabétiques, dont un nouvellement diagnostiqué.Conclusion : A Cotonou, le DM ne semble pas être un facteur de risque majeur de développement d'une TB-maladie. Une étude à l'échelle nationale s'avère nécessaire pour cerner l'ampleur de cette affection parmi les tuberculeux dans tout le pays.

  13. Can shale safely host US nuclear waste?

    USGS Publications Warehouse

    Neuzil, C.E.

    2013-01-01

    "Even as cleanup efforts after Japan’s Fukushima disaster offer a stark reminder of the spent nuclear fuel (SNF) stored at nuclear plants worldwide, the decision in 2009 to scrap Yucca Mountain as a permanent disposal site has dimmed hope for a repository for SNF and other high-level nuclear waste (HLW) in the United States anytime soon. About 70,000 metric tons of SNF are now in pool or dry cask storage at 75 sites across the United States [Government Accountability Office, 2012], and uncertainty about its fate is hobbling future development of nuclear power, increasing costs for utilities, and creating a liability for American taxpayers [Blue Ribbon Commission on America’s Nuclear Future, 2012].However, abandoning Yucca Mountain could also result in broadening geologic options for hosting America’s nuclear waste. Shales and other argillaceous formations (mudrocks, clays, and similar clay-rich media) have been absent from the U.S. repository program. In contrast, France, Switzerland, and Belgium are now planning repositories in argillaceous formations after extensive research in underground laboratories on the safety and feasibility of such an approach [Blue Ribbon Commission on America’s Nuclear Future, 2012; Nationale Genossenschaft für die Lagerung radioaktiver Abfälle (NAGRA), 2010; Organisme national des déchets radioactifs et des matières fissiles enrichies, 2011]. Other nations, notably Japan, Canada, and the United Kingdom, are studying argillaceous formations or may consider them in their siting programs [Japan Atomic Energy Agency, 2012; Nuclear Waste Management Organization (NWMO), (2011a); Powell et al., 2010]."

  14. OASIS4: An Efficient Parallel Code Coupler for Earth System Modelling

    NASA Astrophysics Data System (ADS)

    Coquart, L.; Valcke, S.; Redler, R.; Ritzdorf, H.

    2009-04-01

    As a new development step of the OASIS coupler family, we present OASIS4 in its latest version. OASIS4 is a software allowing synchronized exchanges of coupling information between numerical codes representing different components of the climate system. The concepts of portability, flexibility, parallelism and efficiency are the main drivers for the OASIS4 development with which we target the needs of Earth system modelling in its full complexity. The development and maintenance of OASIS4 has been supported by EU and institutional funding within the PRISM Support Initiative for the past seven years. Here we present the latest version of the OASIS4 coupling software which now includes the commonly known point based 2d and 3d interpolation schemes (bilinear, trilinear, bicubic, nearest neighbour), and 2D conservative remapping. Furthermore, the new version of the software now provides a complete parallel search taking into account specific requirements at process boundaries in order to provide identical search results independently of the domain partitioning. The parallel "multi-grid" search ensures low CPU cost to perform the task of the neighbourhood search and at the same time showing a good scalability when applied to grid partitioned domains. OASIS4 is currently used in few climate applications such as in the FP6 European GEMS project for the 3D coupling between atmosphere and atmosphere chemistry, by the Swedish Meteorological and Hydrological Institute (SMHI) for regional models covering the Arctic Sea or the Baltic area, and by the Calcul Intensif pour le CLimat et l'Environment (CICLE) project funded by the French "Agence Nationale de la Recherche".

  15. Adaptive Automation Triggered by EEG-Based Mental Workload Index: A Passive Brain-Computer Interface Application in Realistic Air Traffic Control Environment.

    PubMed

    Aricò, Pietro; Borghini, Gianluca; Di Flumeri, Gianluca; Colosimo, Alfredo; Bonelli, Stefano; Golfetti, Alessia; Pozzi, Simone; Imbert, Jean-Paul; Granger, Géraud; Benhacene, Raïlane; Babiloni, Fabio

    2016-01-01

    Adaptive Automation (AA) is a promising approach to keep the task workload demand within appropriate levels in order to avoid both the under- and over-load conditions, hence enhancing the overall performance and safety of the human-machine system. The main issue on the use of AA is how to trigger the AA solutions without affecting the operative task. In this regard, passive Brain-Computer Interface (pBCI) systems are a good candidate to activate automation, since they are able to gather information about the covert behavior (e.g., mental workload) of a subject by analyzing its neurophysiological signals (i.e., brain activity), and without interfering with the ongoing operational activity. We proposed a pBCI system able to trigger AA solutions integrated in a realistic Air Traffic Management (ATM) research simulator developed and hosted at ENAC (École Nationale de l'Aviation Civile of Toulouse, France). Twelve Air Traffic Controller (ATCO) students have been involved in the experiment and they have been asked to perform ATM scenarios with and without the support of the AA solutions. Results demonstrated the effectiveness of the proposed pBCI system, since it enabled the AA mostly during the high-demanding conditions (i.e., overload situations) inducing a reduction of the mental workload under which the ATCOs were operating. On the contrary, as desired, the AA was not activated when workload level was under the threshold, to prevent too low demanding conditions that could bring the operator's workload level toward potentially dangerous conditions of underload.

  16. Adaptive Automation Triggered by EEG-Based Mental Workload Index: A Passive Brain-Computer Interface Application in Realistic Air Traffic Control Environment

    PubMed Central

    Aricò, Pietro; Borghini, Gianluca; Di Flumeri, Gianluca; Colosimo, Alfredo; Bonelli, Stefano; Golfetti, Alessia; Pozzi, Simone; Imbert, Jean-Paul; Granger, Géraud; Benhacene, Raïlane; Babiloni, Fabio

    2016-01-01

    Adaptive Automation (AA) is a promising approach to keep the task workload demand within appropriate levels in order to avoid both the under- and over-load conditions, hence enhancing the overall performance and safety of the human-machine system. The main issue on the use of AA is how to trigger the AA solutions without affecting the operative task. In this regard, passive Brain-Computer Interface (pBCI) systems are a good candidate to activate automation, since they are able to gather information about the covert behavior (e.g., mental workload) of a subject by analyzing its neurophysiological signals (i.e., brain activity), and without interfering with the ongoing operational activity. We proposed a pBCI system able to trigger AA solutions integrated in a realistic Air Traffic Management (ATM) research simulator developed and hosted at ENAC (École Nationale de l'Aviation Civile of Toulouse, France). Twelve Air Traffic Controller (ATCO) students have been involved in the experiment and they have been asked to perform ATM scenarios with and without the support of the AA solutions. Results demonstrated the effectiveness of the proposed pBCI system, since it enabled the AA mostly during the high-demanding conditions (i.e., overload situations) inducing a reduction of the mental workload under which the ATCOs were operating. On the contrary, as desired, the AA was not activated when workload level was under the threshold, to prevent too low demanding conditions that could bring the operator's workload level toward potentially dangerous conditions of underload. PMID:27833542

  17. [From Crex mutualisation to clinical audit].

    PubMed

    Debouck, F; Petit, H-B; Lartigau, E

    2010-10-01

    In mid-2004, following a Mission nationale d'expertise et d'audits hospitaliers (MeaH) proposal, three voluntary cancer centres started setting up a safety procedure in radiotherapy. Their work made it possible to single out the need to continue elaborating a repository, aiming at a "minimal written reference", to take into account the human factor as one of the four families of factors contributing to a systemic deviation and to build collectively, in radiotherapy departments, the experience feedback committee (comité de retour d'expérience [Crex]). Formalizing a comité de retour d'expérience is unavoidable in any safety-management system (SMM or MGS). The comité de retour d'expérience enables every active member of a department to listen to any of the events of the month (incidents and precursors), to select the event which will be under scrutiny for the next systemic analysis (Orion(©) method) and above all to choose the most appropriate correcting action and ensure its proper implementation. That approach has been approved and then acknowledged by the Autorité de sûreté nucléaire (ASN) before being extended to the other radiotherapy departments. The use of the comité de retour d'expérience, which is a safety management tool, should not be limited to a local circle of insiders, but shared to benefit everybody. Putting comité de retour d'expérience together - a move that was hoped for and brought up as soon as the tool was created - is now being implemented. Several initiatives have already permitted to assess its collective interest; other steps have yet to be taken to enable a true collective sharing of experience. On this basis, the definition of quality/safety practices in radiotherapy will allow the professionals to implement clinical audits in 2012.

  18. Deep Dermatophytosis and Inherited CARD9 Deficiency

    PubMed Central

    Vincent, Quentin B.; Liu, Luyan; Cypowyj, Sophie; Prando, Carolina; Migaud, Mélanie; Taibi, Lynda; Ammar-Khodja, Aomar; Stambouli, Omar Boudghene; Guellil, Boumediene; Jacobs, Frederique; Goffard, Jean-Christophe; Schepers, Kinda; del Marmol, Véronique; Boussofara, Lobna; Denguezli, Mohamed; Larif, Molka; Bachelez, Hervé; Michel, Laurence; Lefranc, Gérard; Hay, Rod; Jouvion, Gregory; Chretien, Fabrice; Fraitag, Sylvie; Bougnoux, Marie-Elisabeth; Boudia, Merad

    2014-01-01

    BACKGROUND Deep dermatophytosis is a severe and sometimes life-threatening fungal infection caused by dermatophytes. It is characterized by extensive dermal and subcutaneous tissue invasion and by frequent dissemination to the lymph nodes and, occasionally, the central nervous system. The condition is different from common superficial dermatophyte infection and has been reported in patients with no known immunodeficiency. Patients are mostly from North African, consanguineous, multiplex families, which strongly suggests a mendelian genetic cause. METHODS We studied the clinical features of deep dermatophytosis in 17 patients with no known immunodeficiency from eight unrelated Tunisian, Algerian, and Moroccan families. Because CARD9 (caspase recruitment domain–containing protein 9) deficiency has been reported in an Iranian family with invasive fungal infections, we also sequenced CARD9 in the patients. RESULTS Four patients died, at 28, 29, 37, and 39 years of age, with clinically active deep dermatophytosis. No other severe infections, fungal or otherwise, were reported in the surviving patients, who ranged in age from 37 to 75 years. The 15 Algerian and Tunisian patients, from seven unrelated families, had a homozygous Q289X CARD9 allele, due to a founder effect. The 2 Moroccan siblings were homozygous for the R101C CARD9 allele. Both alleles are rare deleterious variants. The familial segregation of these alleles was consistent with autosomal recessive inheritance and complete clinical penetrance. CONCLUSIONS All the patients with deep dermatophytosis had autosomal recessive CARD9 deficiency. Deep dermatophytosis appears to be an important clinical manifestation of CARD9 deficiency. (Funded by Agence Nationale pour la Recherche and others.) PMID:24131138

  19. Using Remotely Piloted Aircraft System to Study the Evolution of the Boundary Layer Related to Fog Events

    NASA Astrophysics Data System (ADS)

    Roberts, G. C.; Cayez, G.; Ronflé-Nadaud, C.; Albrand, M.; Dralet, J. P.; Momboisse, G.; Nicoll, K.; Seity, Y.; Bronz, M.; Hattenberger, G.; Gorraz, M.; Bustico, A.

    2014-12-01

    Over the past decade, the scientific community has embraced the use of RPAS (remotely piloted aircraft system) as a tool to improve observations of the Earth's surface and atmospheric phenomena. The use of small RPAS (Remotely Piloted Aircraft System) in atmospheric research has increased because of their relative low-cost, compact size and ease of operation. Small RPAS are especially adapted for observing the atmospheric boundary layer processes at high vertical and temporal resolution. To this end, CNRM, ENAC, and ENM have developed the VOLTIGE (Vecteurs d'Observation de La Troposphere pour l'Investigation et la Gestion de l'Environnement) program to study the life cycle of fog with multiple, small RPAS. The instrumented RPAS flights have successfully observed the evolution of the boundary layer and dissipation of fog events. In addition, vertical profiles from the RPAS have been compared with Météo France forecast models, and the results suggest that forecast models may be improved using high resolution and frequent in-situ measurements. Within the VOLTIGE project, a flying-wing RPAS with four control surfaces was developed to separate elevator and aileron controls in order to reduce the pitch angle envelope and improve turbulence and albedo measurements. The result leads to a small RPAS with the capability of flying up to two hours with 150 grams of payload, while keeping the hand-launch capability as a constraint for regular atmospheric research missions. High frequency data logging has been integrated into the main autopilot in order to synchronize navigation and payload measurements, as well as allowing an efficient sensor-based navigation. The VOLTIGE program also encourages direct participation of students on the advancement of novel observing systems for atmospheric sciences, and provides a step towards deploying small RPAS in an operational network. VOLTIGE is funded by the Agence Nationale de Recherche (ANR-Blanc 2012) and supported by Aerospace

  20. Atmospheric Measurements by Cavity Enhanced Absorption Spectroscopy

    NASA Astrophysics Data System (ADS)

    Yi, Hongming; Wu, Tao; Coeur-Tourneur, Cécile; Fertein, Eric; Gao, Xiaoming; Zhao, Weixiong; Zhang, Weijun; Chen, Weidong

    2015-04-01

    Since the last decade, atmospheric environmental monitoring has benefited from the development of novel spectroscopic measurement techniques owing to the significant breakthroughs in photonic technology from the UV to the infrared spectral domain [1]. In this presentation, we will overview our recent development and applications of cavity enhanced absorption spectroscopy techniques for in situ optical monitoring of chemically reactive atmospheric species (such as HONO, NO3, NO2, N2O5) in intensive campaigns [2] and/or in smog chamber studies [3]. These field deployments demonstrated that modern photonic technologies (newly emergent light sources combined with high sensitivity spectroscopic techniques) can provide a useful tool to improve our understanding of tropospheric chemical processes which affect climate, air quality, and the spread of pollution. Experimental detail and preliminary results will be presented. Acknowledgements. The financial support from the French Agence Nationale de la Recherche (ANR) under the NexCILAS (ANR-11-NS09-0002) and the CaPPA (ANR-10-LABX-005) contracts is acknowledged. References [1] X. Cui, C. Lengignon, T. Wu, W. Zhao, G. Wysocki, E. Fertein, C. Coeur, A. Cassez,L. Croisé, W. Chen, et al., "Photonic Sensing of the Atmosphere by absorption spectroscopy", J. Quant. Spectrosc. Rad. Transfer 113 (2012) 1300-1316 [2] T. Wu, Q. Zha, W. Chen, Z. XU, T. Wang, X. He, "Development and deployment of a cavity enhanced UV-LED spectrometer for measurements of atmospheric HONO and NO2 in Hong Kong", Atmos. Environ. 95 (2014) 544-551 [3] T. Wu, C. Coeur-Tourneur, G. Dhont,A. Cassez, E. Fertein, X. He, W. Chen,"Application of IBBCEAS to kinetic study of NO3 radical formation from O3 + NO2 reaction in an atmospheric simulation chamber", J. Quant. Spectrosc. Rad. Transfer 133 (2014)199-205

  1. Vigie Ciel a collaborative project to study fireballs and organise meteorite recoveries

    NASA Astrophysics Data System (ADS)

    Colas, F.; Zanda, B.; Bouley, S.; Lewin, E.; Vaubaillon, J.; Marmo, C.; Rotaru, M.; Labenne, L.; Julien, J. F.; Linares, M.; Steinhausser, A.; Rault, J. L.; Vernazza, P.

    2015-10-01

    Research on fireballs and meteorites has always been of interest to the public, due to the beauty of shooting stars in the night sky and to the extraterrestrial origin of meteorites. A fireball observation network called FRIPON [1] (Colas et al, 2015) is currently being setup, funded by ANR (Agence Nationale pour la Recherche). It will cover France with 100 cameras and is expected to be operational for the end of 2015. FRIPON will detect fireballs and hence allow us to define meteorite strewn fields within 24h, so that meteorite searches can be launched very early on. Because of the need to search all over France, including in private land, it is important that the general public be aware of our project and be willing to help or participate. Indeed, as the main goal of FRIPON is to recover fresh meteorites (within a few days), our aim is to be able to organize a search with at least 50 persons to scan an area of a few km2 within a week. Help from the public would hence be most helpful but it is also important to have an operational and trained research team. This project thus appears as a unique occasion to involve the public in a scientific project while promoting informal scientific education. This prompted us to set up Vigie-Ciel, a citizen science network centered on meteorite recovery. FRIPON is an open network based on open-source software, it will accept citizenrun cameras. In addition to fireballs, it will allow scientists and Vigie-Ciel participants to study anything that can be observed by all-sky cameras: bird migrations, bats, clouds, lightning, etc. The data will be freely available to all.

  2. Evidence mapping for decision making: feasibility versus accuracy - when to abandon high sensitivity in electronic searches.

    PubMed

    Buchberger, Barbara; Krabbe, Laura; Lux, Beate; Mattivi, Jessica Tajana

    2016-01-01

    Hintergrund: Evidence Mapping ist eine vergleichsweise neue methodische Herangehensweise, die für die Entwicklung von Forschungsfragen und Entscheidungen über deren Relevanz oder Priorität hilfreich sein kann. Allerdings stellt die Menge der heutzutage zur Verfügung stehenden Daten eine Herausforderung für Wissenschaftler dar, die zum Teil mit Ergebnissen von Datenbankrecherchen konfrontiert sind, die über 30.000 identifizierte Literaturstellen für ein erstes Screening umfassen.Ziele: Zur Überprüfung der Eignung des Themas „Diabetes und Fahrerlaubnis“ als Fragestellung für eine evidenzbasierte nationale klinische Leitlinie wurde ein Evidence Mapping durchgeführt. Darüber hinaus wurde eine hoch sensitive mit einer hoch spezifischen Suchstrategie verglichen.Methoden: Auf der Basis eines systematischen Reviews waren die Datenbankrecherchen auf den Zeitraum von 2002 bis heute begrenzt sowie auf deutsche und englische Publikationen.Ergebnisse: Aufgrund der stark fokussierten Fragestellung und der Begrenzungen ergab die hoch sensitive Recherche eine handhabbare Menge von Literaturstellen, die ausreichend Evidenz enthielten, um die Fragestellung nach der Eignung des Themas für eine evidenzbasierte Leitlinie positiv beantworten zu können. Unter Anwendung der hoch spezifischen Suchstrategie wurde eine Reduktion der Literaturstellen um 25% erreicht, mit der 88% der relevanten Literaturstellen identifiziert werden konnten.Schlussfolgerung: Um eine Übersicht über ein Forschungsgebiet zu erlangen, ist im Gegensatz zu systematischen Reviews, die zur Reduktion von Bias die Darstellung der vollständigen, identifizierbaren Evidenz enthalten müssen, keine Recherche von größter Genauigkeit erforderlich. Unter Berücksichtigung dieses methodischen Unterschieds kann unter Anwendung einer hoch spezifischen Recherche anstelle einer hoch sensitiven eine große Menge zu bearbeitender, aber überflüssiger Informationen vermieden werden.

  3. Tuning ultracold collisions of excited rotational dipolar molecules

    NASA Astrophysics Data System (ADS)

    Quéméner, Goulven

    2015-05-01

    Ultracold molecular dipolar gases often suffer from losses due to chemical reactions (or eventual sticky collisions for non-reactive molecules). Loss suppression for both bosonic and fermionic dipolar species can be obtained in a one-dimensional optical lattice but this requires usually strong confinements to get into a pure two-dimensional collision regime. An alternative way can be found without confinement using rotationally excited molecules. In this talk I will explore the ultracold collisions of rotationally excited dipolar molecules in free space. I will focus on electric dipolar molecules of KRb and electric and magnetic dipolar molecules of RbSr. I will show that we can sharply tune the elastic, inelastic and reactive rate coefficients of lossy molecular collisions when a second rotationally excited colliding channel crosses the threshold of the initial colliding channel, with the help of an applied electric field. We can increase or decrease the loss processes whether the second channel is above or below the initial channel. This could lead to favorable conditions for evaporative cooling. Additionally, we include the electric quadrupole and octopole moment to the dipole moment in the expression of the long-range multipole-multipole interaction. For processes mediated by the incident channel like elastic and loss collisions, the inclusion of quadrupole and octopole moments are not important at ultralow energies. They are important for processes mediated by state-to-state transitions like inelastic collisions. I acknowledge the financial support of the COPOMOL project (ANR-13-IS04-0004) from Agence Nationale de la Recherche.

  4. Regional and yearly variations of hail frequency and intensity in France

    NASA Astrophysics Data System (ADS)

    Berthet, C.; Dessens, J.; Sanchez, J. L.

    2011-06-01

    In addition to the ground seeding hail prevention project, the Association Nationale d'Etude et de Lutte contre les Fléaux Atmosphériques (ANELFA) operates hailpad networks in four of the most hailed regions of France: Atlantic, Pyrenean, Central and Mediterranean. During the past 22 years of continuous measurements, more than five thousand point hailfalls have been recorded at 922 stations (mean annual value) installed in a 66,500 km² area. At the scale of a region and of a hail season, hail is found to be the product of two nearly independent parameters, the frequency and the mean intensity of hailfalls. The frequency is highest in the Pyrenean region, while the intensity is highest both in the Pyrenean and Central regions. This can be explained, for the frequency, by the proximity of Spain, and, for the intensity, by the mean hailstone size distributions which are different in the continental and maritime regions. The time variations and trends of hail during the 1989-2009 period are computed from the data at 457 stations which never changed during this period. The annual frequency is subject to cyclic variations, while the yearly mean intensity is affected by irregular severe hail events. The frequency did not change significantly during the period, while the intensity increased by 70%. The mean monthly distribution of hail is bimodal, with two maximums in May and July, suggesting that two types of meteorological conditions are at the origin of hailstorms. April and May are solely responsible for the mean hail increase observed during the period. A computation of the year-to-year correlation between hail intensity and mean minimum surface temperature for each month suggests that the large hail increase in April and May is at least partially due to the observed concomitant increase in temperature, and then may be a consequence of global warning.

  5. Chondroitin sulfate synthase 1 expression is associated with malignant potential of soft tissue sarcomas with myxoid substance.

    PubMed

    Momose, Takashige; Yoshimura, Yasuo; Harumiya, Satoru; Isobe, Ken'ichi; Kito, Munehisa; Fukushima, Mana; Kato, Hiroyuki; Nakayama, Jun

    2016-04-01

    The glycosyltransferases chondroitin sulfate synthase 1 (CHSY1) and exostoses-like 3 (EXTL3) specifically function in biosynthesis of the glycans chondroitin sulfate and heparan sulfate, respectively. Although these glycans play important roles in pathogenesis of various tumors, their significance in soft tissue sarcoma remains unknown. Here, we asked whether CHSY1 or EXTL3 expression correlates with malignant potential of soft tissue sarcomas with myxoid substance. To do so, we examined 40 samples representing specific types, including 12 cases of myxoid liposarcoma, 14 of myxofibrosarcoma, 12 of malignant peripheral nerve sheath tumor, and 2 of low-grade fibromyxoid sarcoma. We performed immunohistochemistry with anti-CHSY1 and anti-EXTL3 antibodies and compared enzyme expression levels with tumor histologic grade as assessed by the Fédération Nationale des Centres de Lutte Contre le Cancer classification and with patient 5-year survival rate. CHSY1 and EXTL3 were expressed in 72.5% and 32.5% of all tumors, respectively. Notably, CHSY1 was strongly expressed in myxofibrosarcoma and malignant peripheral nerve sheath tumor compared with other tumors and significantly associated with higher- rather than lower-grade tumors (P < .01). High expression of CHSY1 was also significantly associated with poorer patient outcomes (P = .031) and higher stages assessed by American Joint Committee on Cancer staging system (P = .004). By contrast, EXTL3 expression was not correlated with histologic grade or patient prognosis. We conclude that CHSY1 expression is closely associated with malignant potential of soft tissue sarcomas with myxoid substance.

  6. Simple changes within dietary subgroups can rapidly improve the nutrient adequacy of the diet of French adults.

    PubMed

    Verger, Eric O; Holmes, Bridget A; Huneau, Jean François; Mariotti, François

    2014-06-01

    Identifying the dietary changes with the greatest potential for improving diet quality is critical to designing efficient nutrition communication campaigns. Our objective was to simulate the effects of different types of dietary substitutions to improve diet quality at the individual level. Starting from the observed diets of 1330 adults participating in the national French Nutrition and Health Survey (Etude Nationale Nutrition Santé), we simulated the effects of 3 different types of food and beverage substitutions with graded implementation difficulty for the consumer in a stepwise dietary counseling model based on the improvement in the PANDiet index, which measures diet quality in terms of nutrient adequacy. In scenario 1, substitutions of a food or beverage for its "lighter" version resulted in a modest improvement in the PANDiet score (Δ = +3.3 ± 0.1) and a decrease in energy intake (Δ = -114 ± 2 kcal/d). In scenario 2, substitutions of a food or beverage within the same food subgroup resulted in a marked improvement in the PANDiet score (Δ = +26.4 ± 0.2) with no significant change in energy intake. In this second scenario, the improvement in nutrient adequacy was due to substitutions in many subgroups, with no single subgroup contributing >8% to the increase in the PANDiet score. In scenario 3, substitutions of a food or beverage within the same food group resulted in the greatest improvement in the PANDiet score (Δ = +31.8 ± 0.2) but with an increase in energy intake (Δ = +204 ± 9 kcal/d). In this third scenario, the improvement in nutrient adequacy was largely due to substitutions of fish for meat and processed meat (∼30% of the increase in the PANDiet score). This study shows that a strategy based on simple substitutions within food subgroups is effective in rapidly improving the nutritional adequacy of the diet of French adults and could be used in public health nutrition actions.

  7. Douleurs et conflits : Approche comparative et implications pour la qualité des soins en fin de vie

    PubMed Central

    Mpinga, Emmanuel Kabengele; Verloo, Henk; Rapin, Charles-Henri; Chastonay, Philippe

    2009-01-01

    Le conflit serait-il à l’organisation ce que la douleur est à un organisme ? OBJECTIFS: Explorer les similitudes et les differences entre les douleurs et les conflits dans les contextes de soins de fin de vie. Mieux comprendre le rôle des conflits dans la qualité de ces soins. MÉTHODOLOGIE: Méthode comparative et réflexive autour des politiques de prise en charge des douleurs et des conflits dans les systèmes de soins. RÉSULTATS: Les conflits et les douleurs présentent de nombreuses similitudes de par leur identité, leur typologie, leur prévalence, leur fonction d’alerte, leurs coûts économiques et sociaux, le déni ou l’occultation qui les entourent et les obstacles à leur prise en charge adéquate. À l’inverse, des différences apparaissent dans la prise en charge des douleurs comparée à celle des conflits. Ces différences portent sur l’existence des programmes de prévention et de lutte sur les scènes nationale et internationale, la mise en œuvre des activités de recherche et de formation et la visibilité sociale. Pour les conflits, cette mise en œuvre n’existe pas encore. CONCLUSION: Les décideurs en clinique et en santé publique devraient intégrer les conflits comme un indicateur de la qualité des soins et élaborer des politiques pertinentes en matière de santé. PMID:19714268

  8. Protéger les nourrissons contre la coqueluche

    PubMed Central

    Gilley, Meghan; Goldman, Ran D.

    2014-01-01

    Résumé Question Compte tenu du taux à la hausse de la coqueluche chez les enfants, plusieurs familles m’ont demandé quels moyens prendre pour protéger leurs tout-petits de cette infection. Quelles devraient être mes recommandations à ces familles? Réponse La coqueluche est une maladie évitable qui est endémique dans le monde entier. Chez les adultes, la coqueluche cause une maladie bénigne semblable à un rhume, suivie d’une toux persistante. Chez les nourrissons, elle peut causer de l’apnée, des convulsions, une encéphalopathie, une bronchopneumonie et la mort. Les décès dus à la coqueluche se produisent dans 86 % des cas chez des nourrissons de moins de 4 mois. La stratégie du cocooning, c’est-à-dire la vaccination des adultes en étroit contact avec des nourrissons, est recommandée par de nombreuses agences mondiales et nationales, mais elle ne prévient probablement que 20 % des cas de coqueluche chez les nourrissons. La vaccination durant la grossesse est plus efficace, mais elle n’est pas encore approuvée au Canada. Il n’a pas été démontré que la vaccination à la naissance soit uniformément efficace et elle n’est donc pas recommandée à l’heure actuelle.

  9. A Secular Variation Model for Igrf-12 Based on Swarm Data and Inverse Geodynamo Modelling

    NASA Astrophysics Data System (ADS)

    Fournier, A.; Aubert, J.; Erwan, T.

    2014-12-01

    We are proposing a secular variation candidate model for the 12th generation of the international geomagnetic reference field, spanning the years 2015-2020. The novelty of our approach stands in the initialization of a 5-yr long integration of a numerical model of Earth's dynamo by means of inverse geodynamo modelling, as introduced by Aubert (GJI, 2014). This inverse technique combines the information coming from the observations (in the form of an instantaneous estimate of the Gauss coefficients for the magnetic field and its secular variation) with that coming from the multivariate statistics of a free run of a numerical model of the geodynamo. The Gauss coefficients and their error covariance properties are determined from Swarm data along the lines detailed by Thébault et al. (EPS, 2010). The numerical model of the geodynamo is the so-called Coupled Earth Dynamo model (Aubert et al., Nature, 2013), whose variability possesses a strong level of similarity with that of the geomagnetic field. We illustrate and assess the potential of this methodology by applying it to recent time intervals, with an initialization based on CHAMP data, and conclude by presenting our SV candidate, whose initialization is based on the 1st year of Swarm data This work is supported by the French "Agence Nationale de la Recherche" under the grant ANR-11-BS56-011 (http://avsgeomag.ipgp.fr) and by the CNES. References: Aubert, J., Geophys. J. Int. 197, 1321-1334, 2014, doi: 10.1093/gji/ggu064 Aubert, J., Finlay, C., Fournier, F. Nature 502, 219-223, 2013, doi: 10.1038/nature12574 Thébault E. , A. Chulliat, S. Maus, G. Hulot, B. Langais, A. Chambodut and M. Menvielle, Earth Planets Space, Vol. 62 (No. 10), pp. 753-763, 2010.

  10. Préface

    NASA Astrophysics Data System (ADS)

    Hamieh, Tayssir

    2005-05-01

    Né simultanément à Mulhouse et à Beyrouth en 1996 dans le cadre d'une collaboraiion franco-libanaise sur une initiative personnelle de Monsieur Tayssir HAMIEH. le Colloque Franco-Libanais sur la Science des Matériaux (CSM), qui s'inscrit dans le cadre des relations étroites entre la France et le Liban, est très vite devenu une occasion très importante de rencontre entre scientifiques de haut niveau, non seulement, du contour méditerranéen mais également des pays européens, américains et arabes. La quatrieme édition CSM4 est une véritable réussite grâce à la participation des chercheurs confirmés dans tous les domaines des sciences de matériaux et venant de plusieurs pays tels que la France, I'Algérie, Le Liban, la Syrie, le Maroc, la Tunisie, l'Italie, l'Espagne, le Portugal, le Royaume Uni, les États-Unis, la Russie, l'Allemagne, le Japon et I'Inde ; pour présenter plus de 350 communications orales et par affiche et couvrant presque toutes les disciplines des systèmes des matériaux. Le choix des diffèrents thèmes du colloque sur la science des matériaux a été dicté par l'importance capitale de cette discipline dans notre civilisation moderne. En fait, les matériaux utilisés pour la fabrication artisanale ou industrielle d'objets, de produits et de systèmes ainsi que pour la réalisation de constructions et d'équipements ont de tout temps défini le niveau de notre civilisation technique. La réalisation des objectifs communs de notre monde en plein développement, pour ne pas dire en pleine mutation, est en grande partie tributaire de la mise au point de nouveaux matériaux et de procédés de transformation et d'assemblages nouveaux, présentant des performances et des qualités améliorées. Le colloque a illustré et traduit, de manière remarquables, l'excellente collaboration entre chercheurs libanais et français. Le partenariat est exemplaire par la qualité des laboratoires impliqués et par le niveau scientifique des r

  11. Types and quality of physical therapy research publications: has there been a change in the past decade?

    PubMed

    Snell, Kaitlyn; Hassan, Ali; Sutherland, Lauren; Chau, Leo; Senior, Tristan; Janaudis-Ferreira, Tania; Brooks, Dina

    2014-01-01

    Objectif : Décrire et comparer le type et la qualité des données probantes publiées dans les revues de physiothérapie de deux périodes (2010–2012 et 2000–2002) et explorer les opinions des rédacteurs scientifiques sur l'évolution du type et de la qualité des articles. Méthodes : Un examen rétrospectif quantitatif et longitudinal des revues a permis de classer par catégorie les articles publiés dans quatre revues de physiothérapie et d'évaluer leur rigueur méthodologique, grâce au projet Hedges. Une étude transversale descriptive quantitative a permis d'explorer les opinions des rédacteurs scientifiques. Les pourcentages et les fréquences des types d'article (selon la définition des critères du projet Hedges), les articles d'une rigueur suffisante et les réponses des rédacteurs ont été calculés. La signification statistique des différences dans le type et la rigueur des articles entre les deux périodes a été déterminée à l'aide de la méthode exacte de Fisher. Résultats : Il y a eu une importante augmentation dans le nombre d'études originales et d'exposés de synthèse de 2000–2002 à 2010–2012 (p<0,001, p=0,002, respectivement). Le taux de réussite global pour ce qui est de la rigueur était de 33,3% en 2000–2002 et de 42,5% en 2010–2012, ce qui constitue une augmentation importante (p=0,019). La majorité des rédacteurs ont signalé une augmentation des examens systématiques, des conceptions qualitatives, et des essais contrôlés randomisés, et ils étaient d'avis que la qualité s'était améliorée. Conclusion : De 2000–2002 à 2010–2012, la qualité des articles publiés dans les revues de physiothérapie s'est améliorée et la proportion d'études originales et d'exposés de synthèses a augmenté.

  12. Extending the Canada-France brown dwarfs survey to the near-infrared: first ultracool brown dwarfs from CFBDSIR

    NASA Astrophysics Data System (ADS)

    Delorme, P.; Albert, L.; Forveille, T.; Artigau, E.; Delfosse, X.; Reylé, C.; Willott, C. J.; Bertin, E.; Wilkins, S. M.; Allard, F.; Arzoumanian, D.

    2010-07-01

    Aims: We present the first results of the ongoing Canada-France Brown Dwarfs Survey-InfraRed, hereafter CFBDSIR, a near infrared extension to the optical wide-field survey CFBDS. Our final objectives are to constrain ultracool atmosphere physics by finding a statistically significant sample of objects cooler than 650 K and to explore the ultracool brown dwarf mass function building on a well-defined sample of such objects. Methods: We identify candidates in CFHT/WIRCam J and CFHT/MegaCam z' images using optimised psf-fitting, and follow them up with pointed, near-infrared imaging with SOFI at the NTT. We finally obtain low-resolution spectroscopy of the coolest candidates to characterise their atmospheric physics. Results: We have so far analysed and followed up all candidates on the first 66 square degrees of the 335 square degree survey. We identified 55 T-dwarfs candidates with z'-J>3.5 and have confirmed six of them as T-dwarfs, including 3 that are strong later-than-T8 candidates, based on their far-red and NIR colours. We also present here the NIR spectra of one of these ultracool dwarfs, CFBDSIR1458+1013, which confirms it as one of the coolest brown dwarf known, possibly in the 550-600 K temperature range. Conclusions: From the completed survey we expect to discover 10 to 15 dwarfs later than T8, more than doubling the known number of such objects. This will enable detailed studies of their extreme atmospheric properties and provide a stronger statistical basis for studies of their luminosity function. Based on observations obtained with WIRCam, a joint project of CFHT, Taiwan, Korea, Canada, France, and the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada, the Institute National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii. Based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the

  13. La nutrition du nourrisson né à terme et en santé

    PubMed Central

    1998-01-01

    La nutrition du nourrisson né à terme et en santé constitue le nouvel énoncé national sur la nutrition du nourrisson, de la naissance à l’âge de 24 mois. Il s’agit d’un projet conjoint de la Société canadienne de pédiatrie, des Diététistes du Canada et de Santé Canada. Cet ouvrage est une synthèse de la documentation scientifique actuelle en matière de nutrition du nourrisson ; il contient des principes et recommandations afin d’aider les professionnels de la santé à promouvoir la prestation des meilleurs soins alimentaires possibles pour les nourrissons du Canada, compte tenu de l’état actuel de la recherche. La collaboration entre les trois principaux organismes qui s’intéressent à cette question a permis d’uniformisé le message que les professionnels transmettront au public. Le document aborde quatre grands sujets relatifs à la première année d’existence : l’allaitement, les laits de remplacement, les autres liquides dans le régime du nourrisson et la transition aux aliments solides. On y examine ensuite la question de la sécurité dans l’alimentation, puis celle de la nutrition durant la deuxième année. La dernière section couvre les autres questions liées à la nutrition du nourrisson ; on y traite de sujets tels que les allergies alimentaires, les coliques, la constipation, les matières grasses dans le régime alimentaire, la carie dentaire, la gastroentérite, le diabète, l’anémie ferriprive et les régimes végétariens. Le document contient également un répertoire complet de plus de 200 citations. Le sommaire des principes et recommandations paraîtra dans les revues officielles de la Société canadienne de pédiatrie (Paediatrics and Child Health, 1998) et des Diététistes du Canada (Revue canadienne de pratique et de recherche en diététique, juin 1998). On peut télécharger le document intégral à partir des sites Web respectifs des trois organismes associés ; on peut aussi obtenir la

  14. Soins primaires des personnes victimes d’une lésion médullaire

    PubMed Central

    McColl, Mary Ann; Aiken, Alice; McColl, Alexander; Sakakibara, Brodie; Smith, Karen

    2012-01-01

    Résumé Objectif Effectuer une étude de la portée des données empiriques, entre 1980 et 2009, concernant les soins primaires aux adultes victimes d’une lésion médullaire (LME). Sources des données Une recension dans des revues révisées par des pairs de1980 à 2009 à l’aide de CINAHL, PubMed-MEDLINE, EMBASE, PsycINFO, Social Sciences Abstracts et Social Work Abstracts. Sélection des études La recherche électronique au moyen de mots-clés a permis de cerner 42 articles sur les soins primaires et les LME. Des critères d’inclusion ont servi à réduire la liste à un ensemble de 21 articles publiés en anglais qui portaient sur un échantillon de plus de 3 et présentaient une analyse empirique. Synthèse Environ 90 % des personnes atteintes d’une LME ont identifié leur médecin de famille comme étant leur docteur habituel; 63 % avaient un spécialiste des LME. Les personnes vivant à long terme avec une LME développent des rubriques complexes pour naviguer dans leurs systèmes de soins de santé personnels. Les données scientifiques ne sont pas unanimes quant à l’efficacité des programmes d’intervention directe pour le maintien de la santé et la prévention des complications à la suite d’une LME. Les données appuient cependant le suivi périodique par une équipe spécialisée et un bilan de santé annuel complet. La recherche fait valoir un fort degré d’uniformité dans l’identification des problèmes les plus courants soulevés par les personnes atteintes d’une LME en soins primaires, dont la plupart concernent l’incapacité, plus précisément les complications secondaires, comme la dysfonction intestinale ou vésicale et la douleur. Il existe aussi de bonnes données probantes à l’effet que de nombreux problèmes de santé généraux exigent de l’attention dans une telle population, comme les problèmes de la densité osseuse, la dépression et les questions entourant la santé sexuelle et la reproduction. Il y a

  15. The Teen Science Café Network

    NASA Astrophysics Data System (ADS)

    Hall, M.; Mayhew, M. A.

    2013-12-01

    The 'Teen Cafè' phenomenon grew out of an NSF-funded experiment to bring the Cafè Scientifique model for engagement of the public with science and scientists to high school teenagers. Cafè Scientifique New Mexico (cafènm.org), now in its seventh year, has proven highly popular with high school teens for much the same reason as for adult Cafè programs: the blend of socializing in an attractive venue and interaction with a scientist on an interesting science topic. Teen Cafés also include exploration of the topic with hands-on activities. The success of the model has led to the creation of the national Teen Science Cafè Network (teensciencecafe.org. This first year of the new program, four 'Founding Members' of the Network-- in Florida, Colorado, North Carolina, and the St. Louis, Missouri region--started up Teen Cafè programs. Each applied the model with a unique flair appropriate to local institutions and demographics. Each Member in the Network runs Cafès in multiple local venues. We are now gearing up for our second year, and the Network is growing. Our Teen Cafè topics have covered a very wide range, from belly-button biodiversity to cyber-security to patterns of mega-earthquakes to a day in the life of a teen dolphin to corals on acid to emergency room medicine to alternative fuel cars. Presenters have come from a great variety of local institutions. Though they are popular with teens because they are fun and interesting, our evaluations have demonstrated that the programs are having a significant impact on participating teens' understanding of the nature of science, the work that scientists do, and the importance of science to their daily lives. We are also having success in training scientists to communicate effectively with this public audience. Presenters report strong satisfaction with their resulting quality of science communication. A surprising number have reported that their experience with the program has led them to think in a new way about

  16. Sur la reponse en frequence du tissu nerveux dans le cortex

    NASA Astrophysics Data System (ADS)

    Bedard, Claude

    Dans cette These de Physique, nous avons etudie la dependance en frequence du champ electrique du tissu nerveux dans le cortex. Ce champ est aussi designe par "Local field Potential" LFP dans la litterature scientifique. Cette etude est fondee sur la theorie du champ electromagnetisme de Maxwell et sur de l'information tiree de la donne experimentale. Le resultat essentiel de cette These est que la grandeur enorme du temps de relaxation de Maxwell des membranes cellulaires semble etre la cause principale de la dependance en frequence des LFPs. Cette dependance en frequence causee par chaque membrane cellulaire est l'analogue d'un circuit RC ou la resistance R est la resistivite parallele d'une membrane cellulaire, et ou la capacite C est la permittivite electrique de la membrane. L'effet resultant d'un tres grand nombre de cellules donne un spectre de Fourier dont l'enveloppe est tres pres d'un signal en 1/f. Le modele physique propose dans cette These permet de lier les mesures prises a l'interieur d'une dendrite des variations de potentiel electrique a celles prises dans le liquide extracellulaire. De plus, cette These semble ouvrir la possibilite de mesurer le temps de relaxation de Maxwell des membranes cellulaires a l'aide de la mesure de la reponse en frequence du potentiel electrique extracellulaire (LFP). Enfin, cette These permet de lever le voile sur un sujet peu etudie, principalement en raison de la difficulte que represente l'etude des phenomenes electriques dans des milieux complexes comme les tissus vivants. En particulier, le probleme du filtrage frequentiel du potentiel electrique extracellulaire est une propriete fondamentale du tissu nerveux et son origine n'est pas connue.

  17. Histoire du télescope, la contemplation de l'Univers, des premiers instruments aux actuelles machines célestes

    NASA Astrophysics Data System (ADS)

    Nazé, Yaël

    2009-01-01

    Alors que la plupart des scientifiques réalisent leurs expérimentations en laboratoire, les astronomes sont condamnés à ne jamais pouvoir toucher l'objet de leurs travaux: le ciel se laisse contempler mais demeure hors d'atteinte. Pour déchiffrer le message céleste, l'oeil ne suffit pas. Il fallut attendre la naissance de la première lunette astronomique pour ouvrir une nouvelle voie à notre insatiable désir de savoir. Ancêtre de tous les télescopes petits et grands, ce tout premier instrument d'observation allait en effet étendre vers l'infini le pouvoir de nos yeux. Quatre cents ans après, ce sont d'immenses machines qui scrutent pour nous l'Univers, en nous permettant même de remonter le temps. C'est leur histoire qui nous est racontée ici mais, par deçà les engins les plus complexes, ce livre nous parle de leurs bâtisseurs. Démontant au passage certaines idées reçues, ce livre nous plonge dans les balbutiements de ces instruments avant de nous emmener côtoyer les premiers géants et découvrir les révolutions en cours. Illustré de nombreux documents historiques et techniques, ce récit est également pourvu d'encadrés expliquant en profondeur le fonctionnement des instruments.

  18. Changes during hibernation in different phospholipid and free and esterified cholesterol serum levels in black bears

    USGS Publications Warehouse

    Chauhan, V.; Sheikh, A.; Chauhan, A.; Tsiouris, J.; Malik, M.; Vaughan, M.

    2002-01-01

    During hibernation, fat is known to be the preferred source of energy. A detailed analysis of different phospholipids, as well as free and esterified cholesterol, was conducted to investigate lipid abnormalities during hibernation. The levels of total phospholipids and total cholesterol in the serum of black bears were found to increase significantly in hibernation as compared with the active state. Both free and esterified cholesterol were increased in the hibernating state in comparison with the active state (P < 0.05). The percentage increase during hibernation was more in free cholesterol (57%) than in esterified cholesterol (27%). Analysis of subclasses of serum phospholipids showed that choline containing phospholipids, i.e., sphingomyelin (SPG) (14%) and phosphatidylcholine (PC) (76%), are the major phospholipids in the serum of bear. The minor phospholipids included 8% of phosphatidylserine (PS) + phosphatidylinositol (PI), while phosphatidylethanolamine (PE) was only 2% of the total phospholipids. A comparison of phospholipid subclasses showed that PC, PS + PI and SPG were significantly increased, while PE was significantly decreased (P < 0.05) in the hibernating state as compared with the active state in black bears. These results suggest that the catabolism of phospholipids and cholesterol is decreased during hibernation in black bears, leading to their increased levels in the hibernating state as compared with the active state. In summary, our results indicate that serum cholesterol and phospholipid fractions (except PE) are increased during hibernation in bears. It is proposed that the increase of these lipids may be due to the altered metabolism of lipoproteins that are responsible for the clearance of the lipids. ?? 2002 E??ditions scientifiques et me??dicales Elsevier SAS and Socie??te?? franc??aise de biochimie et biologie mole??culaire. All rights reserved.

  19. The magnetic field of ζ Orionis A

    NASA Astrophysics Data System (ADS)

    Blazère, A.; Neiner, C.; Tkachenko, A.; Bouret, J.-C.; Rivinius, Th.

    2015-10-01

    Context. ζ Ori A is a hot star claimed to host a weak magnetic field, but no clear magnetic detection was obtained so far. In addition, it was recently shown to be a binary system composed of a O9.5I supergiant and a B1IV star. Aims: We aim at verifying the presence of a magnetic field in ζ Ori A, identifying to which of the two binary components it belongs (or whether both stars are magnetic), and characterizing the field. Methods: Very high signal-to-noise spectropolarimetric data were obtained with Narval at the Bernard Lyot Telescope (TBL) in France. Archival HEROS, FEROS and UVES spectroscopic data were also used. The data were first disentangled to separate the two components. We then analyzed them with the least-squares deconvolution technique to extract the magnetic information. Results: We confirm that ζ Ori A is magnetic. We find that the supergiant component ζ Ori Aa is the magnetic component: Zeeman signatures are observed and rotational modulation of the longitudinal magnetic field is clearly detected with a period of 6.829 d. This is the only magnetic O supergiant known as of today. With an oblique dipole field model of the Stokes V profiles, we show that the polar field strength is ~140 G. Because the magnetic field is weak and the stellar wind is strong, ζ Ori Aa does not host a centrifugally supported magnetosphere. It may host a dynamical magnetosphere. Its companion ζ Ori Ab does not show any magnetic signature, with an upper limit on the undetected field of ~300 G. Based on observations obtained at the Télescope Bernard Lyot (USR5026) operated by the Observatoire Midi-Pyrénées, Université de Toulouse (Paul Sabatier), Centre National de la Recherche Scientifique of France.Appendix A is available in electronic form at http://www.aanda.org

  20. PHENIX Collaboration

    NASA Astrophysics Data System (ADS)

    Adare, A.; Afanasiev, S.; Aidala, C.; Ajitanand, N. N.; Akiba, Y.; Akimoto, R.; Al-Bataineh, H.; Al-Ta'ani, H.; Alexander, J.; Alfred, M.; Andrews, K. R.; Angerami, A.; Aoki, K.; Apadula, N.; Aphecetche, L.; Appelt, E.; Aramaki, Y.; Armendariz, R.; Aronson, S. H.; Asai, J.; Asano, H.; Aschenauer, E. C.; Atomssa, E. T.; Averbeck, R.; Awes, T. C.; Azmoun, B.; Babintsev, V.; Bai, M.; Bai, X.; Baksay, G.; Baksay, L.; Baldisseri, A.; Bandara, N. S.; Bannier, B.; Barish, K. N.; Barnes, P. D.; Barnes, P. D.; Bassalleck, B.; Basye, A. T.; Bathe, S.; Batsouli, S.; Baublis, V.; Baumann, C.; Baumgart, S.; Bazilevsky, A.; Beaumier, M.; Beckman, S.; Belikov, S.; Belmont, R.; Ben-Benjamin, J.; Bennett, R.; Berdnikov, A.; Berdnikov, Y.; Bhom, J. H.; Bickley, A. A.; Bing, X.; Black, D.; Blau, D. S.; Boissevain, J. G.; Bok, J.; Bok, J. S.; Borel, H.; Boyle, K.; Brooks, M. L.; Broxmeyer, D.; Bryslawskyj, J.; Buesching, H.; Bumazhnov, V.; Bunce, G.; Butsyk, S.; Camacho, C. M.; Campbell, S.; Caringi, A.; Castera, P.; Chang, B. S.; Chang, W. C.; Charvet, J.-L.; Chen, C.-H.; Chernichenko, S.; Chi, C. Y.; Chiba, J.; Chiu, M.; Choi, I. J.; Choi, J. B.; Choi, S.; Choudhury, R. K.; Christiansen, P.; Chujo, T.; Chung, P.; Churyn, A.; Chvala, O.; Cianciolo, V.; Citron, Z.; Cleven, C. R.; Cole, B. A.; Comets, M. P.; Conesa del Valle, Z.; Connors, M.; Constantin, P.; Cronin, N.; Crossette, N.; Csanád, M.; Csörgő, T.; Dahms, T.; Dairaku, S.; Danchev, I.; Das, K.; Datta, A.; Daugherity, M. S.; David, G.; Dayananda, M. K.; Deaton, M. B.; DeBlasio, K.; Dehmelt, K.; Delagrange, H.; Denisov, A.; d'Enterria, D.; Deshpande, A.; Desmond, E. J.; Dharmawardane, K. V.; Dietzsch, O.; Ding, L.; Dion, A.; Do, J. H.; Donadelli, M.; Drapier, O.; Drees, A.; Drees, K. A.; Dubey, A. K.; Durham, J. M.; Durum, A.; Dutta, D.; Dzhordzhadze, V.; D'Orazio, L.; Edwards, S.; Efremenko, Y. V.; Egdemir, J.; Ellinghaus, F.; Emam, W. S.; Engelmore, T.; Enokizono, A.; En'yo, H.; Esumi, S.; Eyser, K. O.; Fadem, B.; Feege, N.; Fields, D. E.; Finger, M.; Finger, M.; Fleuret, F.; Fokin, S. L.; Fraenkel, Z.; Frantz, J. E.; Franz, A.; Frawley, A. D.; Fujiwara, K.; Fukao, Y.; Fusayasu, T.; Gadrat, S.; Gainey, K.; Gal, C.; Gallus, P.; Garg, P.; Garishvili, A.; Garishvili, I.; Ge, H.; Giordano, F.; Glenn, A.; Gong, H.; Gong, X.; Gonin, M.; Gosset, J.; Goto, Y.; Granier de Cassagnac, R.; Grau, N.; Greene, S. V.; Grim, G.; Grosse Perdekamp, M.; Gu, Y.; Gunji, T.; Guo, L.; Guragain, H.; Gustafsson, H.-Å.; Hachiya, T.; Hadj Henni, A.; Haegemann, C.; Haggerty, J. S.; Hahn, K. I.; Hamagaki, H.; Hamblen, J.; Han, R.; Han, S. Y.; Hanks, J.; Harada, H.; Harper, C.; Hartouni, E. P.; Haruna, K.; Hasegawa, S.; Hashimoto, K.; Haslum, E.; Hayano, R.; Hayashi, S.; He, X.; Heffner, M.; Hemmick, T. K.; Hester, T.; Hiejima, H.; Hill, J. C.; Hobbs, R.; Hohlmann, M.; Hollis, R. S.; Holzmann, W.; Homma, K.; Hong, B.; Horaguchi, T.; Hori, Y.; Hornback, D.; Hoshino, T.; Huang, J.; Huang, S.; Ichihara, T.; Ichimiya, R.; Ide, J.; Iinuma, H.; Ikeda, Y.; Imai, K.; Imazu, Y.; Imrek, J.; Inaba, M.; Inoue, Y.; Iordanova, A.; Isenhower, D.; Isenhower, L.; Ishihara, M.; Isinhue, A.; Isobe, T.; Issah, M.; Isupov, A.; Ivanischev, D.; Ivanishchev, D.; Iwanaga, Y.; Jacak, B. V.; Javani, M.; Jeon, S. J.; Jezghani, M.; Jia, J.; Jiang, X.; Jin, J.; Jinnouchi, O.; John, D.; Johnson, B. M.; Jones, T.; Joo, E.; Joo, K. S.; Jouan, D.; Jumper, D. S.; Kajihara, F.; Kametani, S.; Kamihara, N.; Kamin, J.; Kanda, S.; Kaneta, M.; Kaneti, S.; Kang, B. H.; Kang, J. H.; Kang, J. S.; Kanou, H.; Kapustinsky, J.; Karatsu, K.; Kasai, M.; Kawall, D.; Kawashima, M.; Kazantsev, A. V.; Kempel, T.; Key, J. A.; Khachatryan, V.; Khandai, P. K.; Khanzadeev, A.; Kihara, K.; Kijima, K. M.; Kikuchi, J.; Kim, A.; Kim, B. I.; Kim, C.; Kim, D. H.; Kim, D. J.; Kim, E.; Kim, E.-J.; Kim, H.-J.; Kim, H. J.; Kim, K.-B.; Kim, M.; Kim, S. H.; Kim, Y.-J.; Kim, Y. K.; Kinney, E.; Kiriluk, K.; Kiss, Á.; Kistenev, E.; Kiyomichi, A.; Klatsky, J.; Klay, J.; Klein-Boesing, C.; Kleinjan, D.; Kline, P.; Koblesky, T.; Kochenda, L.; Kochetkov, V.; Kofarago, M.; Komatsu, Y.; Komkov, B.; Konno, M.; Koster, J.; Kotchetkov, D.; Kotov, D.; Kozlov, A.; Král, A.; Kravitz, A.; Krizek, F.; Kubart, J.; Kunde, G. J.; Kurihara, N.; Kurita, K.; Kurosawa, M.; Kweon, M. J.; Kwon, Y.; Kyle, G. S.; Lacey, R.; Lai, Y. S.; Lajoie, J. G.; Layton, D.; Lebedev, A.; Lee, B.; Lee, D. M.; Lee, G. H.; Lee, J.; Lee, K.; Lee, K. B.; Lee, K. S.; Lee, M. K.; Lee, S. H.; Lee, S. R.; Lee, T.; Leitch, M. J.; Leite, M. A. L.; Leitgab, M.; Leitner, E.; Lenzi, B.; Lewis, B.; Li, X.; Lichtenwalner, P.; Liebing, P.; Lim, S. H.; Linden Levy, L. A.; Liška, T.; Litvinenko, A.; Liu, H.; Liu, M. X.; Love, B.; Luechtenborg, R.; Lynch, D.; Maguire, C. F.; Makdisi, Y. I.; Maai, M.; Malakhov, A.; Malik, M. D.; Manion, A.; Manko, V. I.; Mannel, E.; Mao, Y.; Maruyama, T.; Mašek, L.; Masui, H.; Masumoto, S.; Matathias, F.; McCumber, M.; McGaughey, P. L.; McGlinchey, D.; McKinney, C.; Means, N.; Meles, A.; Mendoza, M.; Meredith, B.; Miake, Y.; Mibe, T.; Midori, J.; Mignerey, A. C.; Mikeš, P.; Miki, K.; Miller, A. J.; Miller, T. E.; Milov, A.; Mioduszewski, S.; Mishra, D. K.; Mishra, M.; Mitchell, J. T.; Mitrovski, M.; Miyachi, Y.; Miyasaka, S.; Mizuno, S.; Mohanty, A. K.; Montuenga, P.; Moon, H. J.; Moon, T.; Morino, Y.; Morreale, A.; Morrison, D. P.; Moskowitz, M.; Motschwiller, S.; Moukhanova, T. V.; Mukhopadhyay, D.; Murakami, T.; Murata, J.; Mwai, A.; Nagae, T.; Nagamiya, S.; Nagata, Y.; Nagle, J. L.; Naglis, M.; Nagy, M. I.; Nakagawa, I.; Nakagomi, H.; Nakamiya, Y.; Nakamura, K. R.; Nakamura, T.; Nakano, K.; Nam, S.; Nattrass, C.; Nederlof, A.; Netrakanti, P. K.; Newby, J.; Nguyen, M.; Nihashi, M.; Niida, T.; Norman, B. E.; Nouicer, R.; Novak, T.; Novitzky, N.; Nukariya, A.; Nyanin, A. S.; Oakley, C.; Obayashi, H.; O'Brien, E.; Oda, S. X.; Ogilvie, C. A.; Ohnishi, H.; Oide, H.; Oka, M.; Okada, K.; Omiwade, O. O.; Onuki, Y.; Orjuela Koop, J. D.; Oskarsson, A.; Ouchida, M.; Ozaki, H.; Ozawa, K.; Pak, R.; Pal, D.; Palounek, A. P. T.; Pantuev, V.; Papavassiliou, V.; Park, B. H.; Park, I. H.; Park, J.; Park, S.; Park, S. K.; Park, W. J.; Pate, S. F.; Patel, L.; Patel, M.; Pei, H.; Peng, J.-C.; Pereira, H.; Perepelitsa, D. V.; Perera, G. D. N.; Peresedov, V.; Peressounko, D. Yu.; Perry, J.; Petti, R.; Pinkenburg, C.; Pinson, R.; Pisani, R. P.; Proissl, M.; Purschke, M. L.; Purwar, A. K.; Qu, H.; Rak, J.; Rakotozafindrabe, A.; Ravinovich, I.; Read, K. F.; Rembeczki, S.; Reuter, M.; Reygers, K.; Reynolds, D.; Riabov, V.; Riabov, Y.; Richardson, E.; Riveli, N.; Roach, D.; Roche, G.; Rolnick, S. D.; Romana, A.; Rosati, M.; Rosen, C. A.; Rosendahl, S. S. E.; Rosnet, P.; Rowan, Z.; Rubin, J. G.; Rukoyatkin, P.; Ružička, P.; Rykov, V. L.; Ryu, M. S.; Sahlmueller, B.; Saito, N.; Sakaguchi, T.; Sakai, S.; Sakashita, K.; Sakata, H.; Sako, H.; Samsonov, V.; Sano, M.; Sano, S.; Sarsour, M.; Sato, S.; Sato, T.; Savastio, M.; Sawada, S.; Schaefer, B.; Schmoll, B. K.; Sedgwick, K.; Seele, J.; Seidl, R.; Sekiguchi, Y.; Semenov, A. Yu.; Semenov, V.; Sen, A.; Seto, R.; Sett, P.; Sexton, A.; Sharma, D.; Shaver, A.; Shein, I.; Shevel, A.; Shibata, T.-A.; Shigaki, K.; Shim, H. H.; Shimomura, M.; Shoji, K.; Shukla, P.; Sickles, A.; Silva, C. L.; Silvermyr, D.; Silvestre, C.; Sim, K. S.; Singh, B. K.; Singh, C. P.; Singh, V.; Skolnik, M.; Skutnik, S.; Slunečka, M.; Sodre, T.; Solano, S.; Soldatov, A.; Soltz, R. A.; Sondheim, W. E.; Sorensen, S. P.; Soumya, M.; Sourikova, I. V.; Sparks, N. A.; Staley, F.; Stankus, P. W.; Steinberg, P.; Stenlund, E.; Stepanov, M.; Ster, A.; Stoll, S. P.; Stone, M. R.; Sugitate, T.; Suire, C.; Sukhanov, A.; Sumita, T.; Sun, J.; Sziklai, J.; Tabaru, T.; Takagi, S.; Takagui, E. M.; Takahara, A.; Taketani, A.; Tanabe, R.; Tanaka, Y.; Taneja, S.; Tanida, K.; Tannenbaum, M. J.; Tarafdar, S.; Taranenko, A.; Tarján, P.; Tennant, E.; Themann, H.; Thomas, D.; Thomas, T. L.; Timilsina, A.; Todoroki, T.; Togawa, M.; Toia, A.; Tojo, J.; Tomášek, L.; Tomášek, M.; Tomita, Y.; Torii, H.; Towell, M.; Towell, R.; Towell, R. S.; Tram, V.-N.; Tserruya, I.; Tsuchimoto, Y.; Tsuji, T.; Utsunomiya, K.; Vale, C.; Valle, H.; van Hecke, H. W.; Vargyas, M.; Vazquez-Zambrano, E.; Veicht, A.; Velkovska, J.; Vértesi, R.; Vinogradov, A. A.; Virius, M.; Voas, B.; Vossen, A.; Vrba, V.; Vznuzdaev, E.; Wagner, M.; Walker, D.; Wang, X. R.; Watanabe, D.; Watanabe, K.; Watanabe, Y.; Watanabe, Y. S.; Wei, F.; Wei, R.; Wessels, J.; Whitaker, S.; White, S. N.; Winter, D.; Wolin, S.; Wood, J. P.; Woody, C. L.; Wright, R. M.; Wysocki, M.; Xia, B.; Xie, W.; Xue, L.; Yalcin, S.; Yamaguchi, Y. L.; Yamaura, K.; Yang, R.; Yanovich, A.; Yasin, Z.; Ying, J.; Yokkaichi, S.; Yoo, J. S.; Yoon, I.; You, Z.; Young, G. R.; Younus, I.; Yushmanov, I. E.; Zajc, W. A.; Zaudtke, O.; Zelenski, A.; Zhang, C.; Zhou, S.; Zimányi, J.; Zolin, L.

    2014-11-01

    We thank the staff of the Collider-Accelerator and Physics Departments at Brookhaven National Laboratory and the staff of the other PHENIX participating institutions for their vital contributions. We acknowledge support from the Office of Nuclear Physics in the Office of Science of the Department of Energy, the National Science Foundation, a sponsored research grant from Renaissance Technologies LLC, Abilene Christian University Research Council, Research Foundation of SUNY, and Dean of the College of Arts and Sciences, Vanderbilt University (USA), Ministry of Education, Culture, Sports, Science, and Technology and the Japan Society for the Promotion of Science (Japan), Conselho Nacional de Desenvolvimento Científico e Tecnológico and Fundaç ao de Amparo à Pesquisa do Estado de São Paulo (Brazil), Natural Science Foundation of China (People's Republic of China), Ministry of Science, Education, and Sports (Croatia), Ministry of Education, Youth and Sports (Czech Republic), Centre National de la Recherche Scientifique, Commissariat à l'Énergie Atomique, and Institut National de Physique Nucléaire et de Physique des Particules (France), Bundesministerium für Bildung und Forschung, Deutscher Akademischer Austausch Dienst, and Alexander von Humboldt Stiftung (Germany), OTKA NK 101 428 grant and the Ch. Simonyi Fund (Hungary), Department of Atomic Energy and Department of Science and Technology (India), Israel Science Foundation (Israel), National Research Foundation and WCU program of the Ministry Education Science and Technology (Korea), Physics Department, Lahore University of Management Sciences (Pakistan), Ministry of Education and Science, Russian Academy of Sciences, Federal Agency of Atomic Energy (Russia), VR and Wallenberg Foundation (Sweden), the US Civilian Research and Development Foundation for the Independent States of the Former Soviet Union, and the US-Israel Binational Science Foundation.

  1. Apport des neutrons à l'analyse structurale des composés partiellement désordonnés

    NASA Astrophysics Data System (ADS)

    Cousson, A.

    2003-02-01

    La cristallographie est un outil extrêmement puissant qui pourrait être utilisé par de nombreux scientifiques dont les sujets de recherche sont en fait très éloignés. L'évolution des techniques ces dernières années a relégué par exemple la cristallographie des rayons X des petites molécules à un rôle mineur, un rôle de service. Certains ont même le sentiment semble-t-il que toutes les connaissances sont contenues dans de multiples logiciels capables par eux-mêmes de conduire une analyse structurale à un résultat correct unique. Il est souhaitable que chacun soit capable de réaliser l'étude structurale du composé qui l'intéresse et bien entendu nécessaire de comprendre ce que l'on fait, la qualité des résultats et leur analyse en dépend. L'objet de cette présentation est de montrer l'apport spécifique de la diffraction de neutrons sur monocristaux à l'étude du désordre, en particulier des atomes d'hydrogène, et ses conséquences sur la compréhension des propriétés physiques, à partir de développements et d'exemples récents.

  2. Preventive Home Visits for Older People: A Systematic Review.

    PubMed

    Tourigny, André; Bédard, Annick; Laurin, Danielle; Kröger, Edeltraut; Durand, Pierre; Bonin, Lucie; Sévigny, Andrée; Frappier, Annie; Roussel, Marie Ève; Martin, Mélanie

    2015-12-01

    RÉSUMÉ L'augmentation du nombre de personnes âgées présentant des incapacités et ayant des maladies chroniques entraîne une hausse des besoins en services de santé à domicile. Le nombre d'études et de revues systématiques traitant des approches préventives pour cette clientèle a proliféré, générant un besoin de synthèse des connaissances. Nous avons mené une revue systématique de revues systématiques évaluant l'effet des programmes de visite préventive pour les personnes âgées. Des 5 973 citations identifiées dans plus de 30 bases de données de littérature grise et scientifique, 10 articles répondaient à tous les critères d'inclusion. Les revues systématiques étaient retenues si elles comprenaient des essais randomisés contrôlés comparant des interventions de soins à domicile offerts par un professionnel de la santé et ceux sans professionnels. Les interventions sont souvent des évaluations gériatriques globales et s'accompagnent de visites de suivi. Il ressort que les visites préventives multidimensionnelles à domicile ont le potentiel de diminuer la mortalité, en particulier chez les personnes âgées plus jeunes, et offrent aussi un potentiel d'amélioration de l'autonomie fonctionnelle. Toutefois, ces résultats doivent être interprétés avec prudence vue la diversité des interventions analysées.

  3. The BNM-LPTF software for the frequency comparison of atomic clocks by the carrier phase of the GPS signal.

    PubMed

    Taris, F; Uhrich, P; Petit, G; Jiang, Z; Barillet, R; Hamouda, F

    2000-01-01

    This paper describes the software and equipment used at the Laboratoire Primaire du Temps et des Frequences du Bureau National de Metrologie (BNM-LPTF), Paris, France. Two H-masers in short baseline, one located at the BNM-LPTF and the other at the Laboratoire de l'Horloge Atomique du Centre National de la Recherche Scientifique (CNRS-LHA), Orsay, France, were computed in parallel with the BNM-LPTF software and with the BERNESE V 4.1 software. The comparison of the results issued from both computations shows an agreement within 100 ps (1 sigma). In addition, comparisons with the BNM-LPTF software were made over 10 days with the H-masers located at the Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany, and another at the National Physical Laboratory (NPL), Teddington, United Kingdom. The data collected show that a modulation with an amplitude of 50 ps and a period of 700-800 ps affects the equipment of the NPL. In addition, these comparisons show that the noise of the instruments together with the environmental conditions at the PTB was higher than that of the NPL and the BNM-LPTF during the observation period. The best relative frequency stability obtained, in the BNM-LPTF/NPL comparison, is about 3x10(-15) for averaging periods between 6x10(4) s and 3x10(5) s. This result is in good agreement with the expected stability of H-masers. It demonstrates that the noise brought by the GPS carrier phase measurements can be averaged out at this level.

  4. The Discovery of an Ultra-faint Star Cluster in the Constellation of Ursa Minor

    NASA Astrophysics Data System (ADS)

    Muñoz, R. R.; Geha, M.; Côté, P.; Vargas, L. C.; Santana, F. A.; Stetson, P.; Simon, J. D.; Djorgovski, S. G.

    2012-07-01

    We report the discovery of a new ultra-faint globular cluster in the constellation of Ursa Minor, based on stellar photometry from the MegaCam imager at the Canada-France-Hawaii Telescope. We find that this cluster, Muñoz 1, is located at a distance of 45 ± 5 kpc and at a projected distance of only 45' from the center of the Ursa Minor dwarf spheroidal galaxy. Using a maximum-likelihood technique we measure a half-light radius of 0farcm5, or equivalently 7 pc, and an ellipticity consistent with being zero. We estimate its absolute magnitude to be MV = -0.4 ± 0.9, which corresponds to LV = 120+160 -65 L ⊙ and we measure a heliocentric radial velocity of -137 ± 4 km s-1 based on Keck/DEIMOS spectroscopy. This new satellite is separate from Ursa Minor by ~30 kpc and 110 km s-1 suggesting the cluster is not obviously associated with the dSph, despite the very close angular separation. Based on its photometric properties and structural parameters we conclude that Muñoz 1 is a new ultra-faint stellar cluster. Along with Segue 3 this is one of the faintest stellar clusters known to date. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii. Spectroscopic data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration.

  5. Calibration, Sensor Model Improvements and Uncertainty Budget of the Airborne Imaging Spectrometer APEX

    NASA Astrophysics Data System (ADS)

    Hueni, A.

    2015-12-01

    ESA's Airborne Imaging Spectrometer APEX (Airborne Prism Experiment) was developed under the PRODEX (PROgramme de Développement d'EXpériences scientifiques) program by a Swiss-Belgian consortium and entered its operational phase at the end of 2010 (Schaepman et al., 2015). Work on the sensor model has been carried out extensively within the framework of European Metrology Research Program as part of the Metrology for Earth Observation and Climate (MetEOC and MetEOC2). The focus has been to improve laboratory calibration procedures in order to reduce uncertainties, to establish a laboratory uncertainty budget and to upgrade the sensor model to compensate for sensor specific biases. The updated sensor model relies largely on data collected during dedicated characterisation experiments in the APEX calibration home base but includes airborne data as well where the simulation of environmental conditions in the given laboratory setup was not feasible. The additions to the model deal with artefacts caused by environmental changes and electronic features, namely the impact of ambient air pressure changes on the radiometry in combination with dichroic coatings, influences of external air temperatures and consequently instrument baffle temperatures on the radiometry, and electronic anomalies causing radiometric errors in the four shortwave infrared detector readout blocks. Many of these resolved issues might be expected to be present in other imaging spectrometers to some degree or in some variation. Consequently, the work clearly shows the difficulties of extending a laboratory-based uncertainty to data collected under in-flight conditions. The results are hence not only of interest to the calibration scientist but also to the spectroscopy end user, in particular when commercial sensor systems are used for data collection and relevant sensor characteristic information tends to be sparse. Schaepman, et al, 2015. Advanced radiometry measurements and Earth science

  6. A Multi-wavelength Mass Analysis of RCS2 J232727.6-020437, A ˜3 × 1015 M⊙ Galaxy Cluster at z = 0.7

    NASA Astrophysics Data System (ADS)

    Sharon, K.; Gladders, M. D.; Marrone, D. P.; Hoekstra, H.; Rasia, E.; Bourdin, H.; Gifford, D.; Hicks, A. K.; Greer, C.; Mroczkowski, T.; Barrientos, L. F.; Bayliss, M.; Carlstrom, J. E.; Gilbank, D. G.; Gralla, M.; Hlavacek-Larrondo, J.; Leitch, E.; Mazzotta, P.; Miller, C.; Muchovej, S. J. C.; Schrabback, T.; Yee, H. K. C.; RCS-Team

    2015-11-01

    We present an initial study of the mass and evolutionary state of a massive and distant cluster, RCS2 J232727.6-020437. This cluster, at z = 0.6986, is the richest cluster discovered in the RCS2 project. The mass measurements presented in this paper are derived from all possible mass proxies: X-ray measurements, weak-lensing shear, strong lensing, Sunyaev-Zel’dovich effect decrement, the velocity distribution of cluster member galaxies, and galaxy richness. While each of these observables probe the mass of the cluster at a different radius, they all indicate that RCS2 J232727.6-020437 is among the most massive clusters at this redshift, with an estimated mass of {M}200˜ 3× {10}15{h}70-1 {M}⊙ . In this paper, we demonstrate that the various observables are all reasonably consistent with each other to within their uncertainties. RCS2 J232727.6-020437 appears to be well relaxed—with circular and concentric X-ray isophotes, with a cool core, and no indication of significant substructure in extensive galaxy velocity data. Based on observations obtained with : MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada, the Institut National des Science de l’Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii; the NASA/ESA Hubble Space Telescope (HST), obtained from the data archive at the Space Telescope Institute. STScI is operated by the association of Universities for Research in Astronomy, Inc. under the NASA contract NAS 5-2655; the 6.5 m Magellan telescopes located at Las Campanas Observatory, Chile;

  7. Submillimeter Galaxies at z ~ 2: Evidence for Major Mergers and Constraints on Lifetimes, IMF, and CO-H2 Conversion Factor

    NASA Astrophysics Data System (ADS)

    Tacconi, L. J.; Genzel, R.; Smail, I.; Neri, R.; Chapman, S. C.; Ivison, R. J.; Blain, A.; Cox, P.; Omont, A.; Bertoldi, F.; Greve, T.; Förster Schreiber, N. M.; Genel, S.; Lutz, D.; Swinbank, A. M.; Shapley, A. E.; Erb, D. K.; Cimatti, A.; Daddi, E.; Baker, A. J.

    2008-06-01

    We report subarcsecond resolution IRAM PdBI millimeter CO interferometry of four z ~ 2 submillimeter galaxies (SMGs), and sensitive CO(3-2) flux limits toward three z ~ 2 UV/optically selected star-forming galaxies. The new data reveal for the first time spatially resolved CO gas kinematics in the observed SMGs. Two of the SMGs show double or multiple morphologies, with complex, disturbed gas motions. The other two SMGs exhibit CO velocity gradients of ~500 km s-1 across <=0.2'' (1.6 kpc) diameter regions, suggesting that the star-forming gas is in compact, rotating disks. Our data provide compelling evidence that these SMGs represent extreme, short-lived "maximum" star-forming events in highly dissipative mergers of gas-rich galaxies. The resulting high-mass surface and volume densities of SMGs are similar to those of compact quiescent galaxies in the same redshift range and much higher than those in local spheroids. From the ratio of the comoving volume densities of SMGs and quiescent galaxies in the same mass and redshift ranges, and from the comparison of gas exhaustion timescales and stellar ages, we estimate that the SMG phase duration is about 100 Myr. Our analysis of SMGs and optically/UV selected high-redshift star-forming galaxies supports a "universal" Chabrier IMF as being valid over the star-forming history of these galaxies. We find that the 12CO luminosity to total gas mass conversion factors at z ~ 2-3 are probably similar to those assumed at z ~ 0. The implied gas fractions in our sample galaxies range from 20% to 50%. Based on observations obtained at the IRAM Plateau de Bure Interferometer (PdBI). IRAM is funded by the Centre National de la Recherché Scientifique (France), the Max-Planck Gesellschaft (Germany), and the Instituto Geografico Nacional (Spain).

  8. Single Star Scidar first light from Dome C

    NASA Astrophysics Data System (ADS)

    Vernin, J.; Chadid-Vernin, M.; Aristidi, E.; Trinquet, H.; Sadibekova, T.

    2006-08-01

    Here, we present the SSS first light from Dome C Antarctica. Results obtained during Chadid's expedition in the Summer Season 2005-2006 . The alpha Car observations are obtained during the day and using a 40 cm telescope. The SSS "Single Star Scidar" technique derives from the so-called Scidar (SCIntillation Detection and Ranging) technique, which analyses the scintillation, on the entrance pupil of a telescope, of a double star. The scientific goal is to measure vertical profiles of the Optical Turbulence C_N ^2 (h) and the wind speed *V*(h) at Dome C from the scintillation of a single star. From those two profiles it is possible to deduce almost all the parameters which can help to optimize all the instruments devoted to High Angular Resolution Astronomy, such as Adaptive Optics and Interferometry. The SSS at Dome C is composed of a 40 cm telescope driven by an equatorial mount. A short focal lens is used to collimate the optical beam, and the defocussed image of the telescope pupil is acquired by a CCD. Several thousands of images are analyzed in real time to deliver spatio-temporal cross correlations. Each few tens of seconds, such a correlation is stored in order be processed off line with the "simulated annealing" method. The development and construction of this instrument was made possible with help of: Air Force Office of Scientific Research and the European Office of Aerospace Research and Development (USA), Programmes Internationaux de Cooperation Scientifique, INSU and CNRS contracts, a European "ELT Design Study" contract, the IPEV infrastructure and financing, AFRL-VSBYA (USA), IAC (Spain) and ANR "CASDOA" contract.

  9. Influence of Aeration and of Pantothenate on Growth Yields of Zymomonas mobilis

    PubMed Central

    Belaïch, Jean-Pierre; Senez, Jacques C.

    1965-01-01

    Belaïch, Jean-Pierre (Centre National de la Recherche Scientifique, Marseille, France), and Jacques C. Senez. Influence of aeration and of pantothenate on growth yields of Zymomonas mobilis. J. Bacteriol. 89:1195–1200. 1965.—The growth yields and rates of Zymomonas mobilis were measured in aerobic and anaerobic cultures on glucose medium containing yeast extract, amino acids, or ammonium chloride as the nitrogen source. In the absence of yeast extract, pantothenate was required. The growth yield and rate of the cultures in synthetic (amino acids) or minimal (NH4Cl) medium supplemented with pantothenate corresponded only to about one-half the “normal” values obtained in the presence of yeast extract, suggesting a situation of energetically uncoupled growth. Attempts to restore normal growth by the addition of various compounds were unsuccessful. Aeration of the cultures resulted in a partial oxidation of ethyl alcohol to acetate, but did not modify the growth yield nor the division time. Both aerobic and anaerobic cells, however, contained cytochrome c and a cytochrome oxidase of the a2 type, which was completely inhibited by 10−4m cyanide. In anaerobically grown cells, an additional cytochrome of the b type was present. The absence of a Pasteur effect suggests that the transfer of electrons by the respiratory chain of Z. mobilis may not be coupled with oxidative phosphorylation. Aeration had no effect on the catalase content of the cells. As shown by C14-glucose incorporation, 2 to 3% of the glucose metabolized was assimilated by the cells in both synthetic and rich complex medium. No intracellular glycogen nor poly-β-hydroxybutyrate was accumulated when growth was limited by nitrogen or by phosphate in the presence of excess glucose. PMID:14292985

  10. PHENIX Collaboration

    NASA Astrophysics Data System (ADS)

    Adare, A.; Afanasiev, S.; Aidala, C.; Ajitanand, N. N.; Akiba, Y.; Akimoto, R.; Al-Bataineh, H.; Al-Ta'ani, H.; Alexander, J.; Alfred, M.; Andrews, K. R.; Angerami, A.; Aoki, K.; Apadula, N.; Aphecetche, L.; Appelt, E.; Aramaki, Y.; Armendariz, R.; Aronson, S. H.; Asai, J.; Asano, H.; Aschenauer, E. C.; Atomssa, E. T.; Averbeck, R.; Awes, T. C.; Azmoun, B.; Babintsev, V.; Bai, M.; Bai, X.; Baksay, G.; Baksay, L.; Baldisseri, A.; Bandara, N. S.; Bannier, B.; Barish, K. N.; Barnes, P. D.; Bassalleck, B.; Basye, A. T.; Bathe, S.; Batsouli, S.; Baublis, V.; Baumann, C.; Baumgart, S.; Bazilevsky, A.; Beaumier, M.; Beckman, S.; Belikov, S.; Belmont, R.; Ben-Benjamin, J.; Bennett, R.; Berdnikov, A.; Berdnikov, Y.; Bhom, J. H.; Bickley, A. A.; Bing, X.; Black, D.; Blau, D. S.; Boissevain, J. G.; Bok, J. S.; Borel, H.; Boyle, K.; Brooks, M. L.; Broxmeyer, D.; Bryslawskyj, J.; Buesching, H.; Bumazhnov, V.; Bunce, G.; Butsyk, S.; Camacho, C. M.; Campbell, S.; Caringi, A.; Castera, P.; Chang, B. S.; Chang, W. C.; Charvet, J.-L.; Chen, C.-H.; Chernichenko, S.; Chi, C. Y.; Chiba, J.; Chiu, M.; Choi, I. J.; Choi, J. B.; Choi, S.; Choudhury, R. K.; Christiansen, P.; Chujo, T.; Chung, P.; Churyn, A.; Chvala, O.; Cianciolo, V.; Citron, Z.; Cleven, C. R.; Cole, B. A.; Comets, M. P.; Conesa del Valle, Z.; Connors, M.; Constantin, P.; Cronin, N.; Crossette, N.; Csanád, M.; Csörgő, T.; Dahms, T.; Dairaku, S.; Danchev, I.; Das, K.; Datta, A.; Daugherity, M. S.; David, G.; Dayananda, M. K.; Deaton, M. B.; DeBlasio, K.; Dehmelt, K.; Delagrange, H.; Denisov, A.; d'Enterria, D.; Deshpande, A.; Desmond, E. J.; Dharmawardane, K. V.; Dietzsch, O.; Ding, L.; Dion, A.; Do, J. H.; Donadelli, M.; Drapier, O.; Drees, A.; Drees, K. A.; Dubey, A. K.; Durham, J. M.; Durum, A.; Dutta, D.; Dzhordzhadze, V.; D'Orazio, L.; Edwards, S.; Efremenko, Y. V.; Egdemir, J.; Ellinghaus, F.; Emam, W. S.; Engelmore, T.; Enokizono, A.; En'yo, H.; Esumi, S.; Eyser, K. O.; Fadem, B.; Feege, N.; Fields, D. E.; Finger, M.; Finger, M.; Fleuret, F.; Fokin, S. L.; Fraenkel, Z.; Frantz, J. E.; Franz, A.; Frawley, A. D.; Fujiwara, K.; Fukao, Y.; Fusayasu, T.; Gadrat, S.; Gainey, K.; Gal, C.; Gallus, P.; Garg, P.; Garishvili, A.; Garishvili, I.; Ge, H.; Giordano, F.; Glenn, A.; Gong, H.; Gong, X.; Gonin, M.; Gosset, J.; Goto, Y.; Granier de Cassagnac, R.; Grau, N.; Greene, S. V.; Grim, G.; Grosse Perdekamp, M.; Gu, Y.; Gunji, T.; Guo, L.; Guragain, H.; Gustafsson, H.-Å.; Hachiya, T.; Hadj Henni, A.; Haegemann, C.; Haggerty, J. S.; Hahn, K. I.; Hamagaki, H.; Hamblen, J.; Han, R.; Han, S. Y.; Hanks, J.; Harada, H.; Harper, C.; Hartouni, E. P.; Haruna, K.; Hasegawa, S.; Hashimoto, K.; Haslum, E.; Hayano, R.; Hayashi, S.; He, X.; Heffner, M.; Hemmick, T. K.; Hester, T.; Hiejima, H.; Hill, J. C.; Hobbs, R.; Hohlmann, M.; Hollis, R. S.; Holzmann, W.; Homma, K.; Hong, B.; Horaguchi, T.; Hori, Y.; Hornback, D.; Hoshino, T.; Huang, J.; Huang, S.; Ichihara, T.; Ichimiya, R.; Ide, J.; Iinuma, H.; Ikeda, Y.; Imai, K.; Imazu, Y.; Imrek, J.; Inaba, M.; Inoue, Y.; Iordanova, A.; Isenhower, D.; Isenhower, L.; Ishihara, M.; Isinhue, A.; Isobe, T.; Issah, M.; Isupov, A.; Ivanischev, D.; Ivanishchev, D.; Iwanaga, Y.; Jacak, B. V.; Javani, M.; Jeon, S. J.; Jezghani, M.; Jia, J.; Jiang, X.; Jin, J.; Jinnouchi, O.; John, D.; Johnson, B. M.; Jones, T.; Joo, E.; Joo, K. S.; Jouan, D.; Jumper, D. S.; Kajihara, F.; Kametani, S.; Kamihara, N.; Kamin, J.; Kanda, S.; Kaneta, M.; Kaneti, S.; Kang, B. H.; Kang, J. H.; Kang, J. S.; Kanou, H.; Kapustinsky, J.; Karatsu, K.; Kasai, M.; Kawall, D.; Kawashima, M.; Kazantsev, A. V.; Kempel, T.; Key, J. A.; Khachatryan, V.; Khandai, P. K.; Khanzadeev, A.; Kihara, K.; Kijima, K. M.; Kikuchi, J.; Kim, A.; Kim, B. I.; Kim, C.; Kim, D. H.; Kim, D. J.; Kim, E.; Kim, E.-J.; Kim, H.-J.; Kim, H. J.; Kim, K.-B.; Kim, M.; Kim, S. H.; Kim, Y.-J.; Kim, Y. K.; Kinney, E.; Kiriluk, K.; Kiss, Á.; Kistenev, E.; Kiyomichi, A.; Klatsky, J.; Klay, J.; Klein-Boesing, C.; Kleinjan, D.; Kline, P.; Koblesky, T.; Kochenda, L.; Kochetkov, V.; Kofarago, M.; Komatsu, Y.; Komkov, B.; Konno, M.; Koster, J.; Kotchetkov, D.; Kotov, D.; Kozlov, A.; Král, A.; Kravitz, A.; Krizek, F.; Kubart, J.; Kunde, G. J.; Kurihara, N.; Kurita, K.; Kurosawa, M.; Kweon, M. J.; Kwon, Y.; Kyle, G. S.; Lacey, R.; Lai, Y. S.; Lajoie, J. G.; Layton, D.; Lebedev, A.; Lee, B.; Lee, D. M.; Lee, G. H.; Lee, J.; Lee, K.; Lee, K. B.; Lee, K. S.; Lee, M. K.; Lee, S. H.; Lee, S. R.; Lee, T.; Leitch, M. J.; Leite, M. A. L.; Leitgab, M.; Leitner, E.; Lenzi, B.; Lewis, B.; Li, X.; Lichtenwalner, P.; Liebing, P.; Lim, S. H.; Linden Levy, L. A.; Liška, T.; Litvinenko, A.; Liu, H.; Liu, M. X.; Love, B.; Luechtenborg, R.; Lynch, D.; Maguire, C. F.; Makdisi, Y. I.; Ma, M.; Malakhov, A.; Malik, M. D.; Manion, A.; Manko, V. I.; Mannel, E.; Mao, Y.; Maruyama, T.; Mašek, L.; Masui, H.; Masumoto, S.; Matathias, F.; McCumber, M.; McGaughey, P. L.; McGlinchey, D.; McKinney, C.; Means, N.; Meles, A.; Mendoza, M.; Meredith, B.; Miake, Y.; Mibe, T.; Midori, J.; Mignerey, A. C.; Mikeš, P.; Miki, K.; Miller, A. J.; Miller, T. E.; Milov, A.; Mioduszewski, S.; Mishra, D. K.; Mishra, M.; Mitchell, J. T.; Mitrovski, M.; Miyachi, Y.; Miyasaka, S.; Mizuno, S.; Mohanty, A. K.; Montuenga, P.; Moon, H. J.; Moon, T.; Morino, Y.; Morreale, A.; Morrison, D. P.; Moskowitz, M.; Motschwiller, S.; Moukhanova, T. V.; Mukhopadhyay, D.; Murakami, T.; Murata, J.; Mwai, A.; Nagae, T.; Nagamiya, S.; Nagata, Y.; Nagle, J. L.; Naglis, M.; Nagy, M. I.; Nakagawa, I.; Nakagomi, H.; Nakamiya, Y.; Nakamura, K. R.; Nakamura, T.; Nakano, K.; Nam, S.; Nattrass, C.; Nederlof, A.; Netrakanti, P. K.; Newby, J.; Nguyen, M.; Nihashi, M.; Niida, T.; Norman, B. E.; Nouicer, R.; Novak, T.; Novitzky, N.; Nukariya, A.; Nyanin, A. S.; Oakley, C.; Obayashi, H.; O'Brien, E.; Oda, S. X.; Ogilvie, C. A.; Ohnishi, H.; Oide, H.; Oka, M.; Okada, K.; Omiwade, O. O.; Onuki, Y.; Orjuela Koop, J. D.; Oskarsson, A.; Ouchida, M.; Ozaki, H.; Ozawa, K.; Pak, R.; Pal, D.; Palounek, A. P. T.; Pantuev, V.; Papavassiliou, V.; Park, B. H.; Park, I. H.; Park, J.; Park, S.; Park, S. K.; Park, W. J.; Pate, S. F.; Patel, L.; Patel, M.; Pei, H.; Peng, J.-C.; Pereira, H.; Perepelitsa, D. V.; Perera, G. D. N.; Peresedov, V.; Peressounko, D. Yu.; Perry, J.; Petti, R.; Pinkenburg, C.; Pinson, R.; Pisani, R. P.; Proissl, M.; Purschke, M. L.; Purwar, A. K.; Qu, H.; Rak, J.; Rakotozafindrabe, A.; Ravinovich, I.; Read, K. F.; Rembeczki, S.; Reuter, M.; Reygers, K.; Reynolds, D.; Riabov, V.; Riabov, Y.; Richardson, E.; Riveli, N.; Roach, D.; Roche, G.; Rolnick, S. D.; Romana, A.; Rosati, M.; Rosen, C. A.; Rosendahl, S. S. E.; Rosnet, P.; Rowan, Z.; Rubin, J. G.; Rukoyatkin, P.; Ružička, P.; Rykov, V. L.; Ryu, M. S.; Sahlmueller, B.; Saito, N.; Sakaguchi, T.; Sakai, S.; Sakashita, K.; Sakata, H.; Sako, H.; Samsonov, V.; Sano, M.; Sano, S.; Sarsour, M.; Sato, S.; Sato, T.; Savastio, M.; Sawada, S.; Schaefer, B.; Schmoll, B. K.; Sedgwick, K.; Seele, J.; Seidl, R.; Sekiguchi, Y.; Semenov, A. Yu.; Semenov, V.; Sen, A.; Seto, R.; Sett, P.; Sexton, A.; Sharma, D.; Shaver, A.; Shein, I.; Shevel, A.; Shibata, T.-A.; Shigaki, K.; Shim, H. H.; Shimomura, M.; Shoji, K.; Shukla, P.; Sickles, A.; Silva, C. L.; Silvermyr, D.; Silvestre, C.; Sim, K. S.; Singh, B. K.; Singh, C. P.; Singh, V.; Skolnik, M.; Skutnik, S.; Slunečka, M.; Sodre, T.; Solano, S.; Soldatov, A.; Soltz, R. A.; Sondheim, W. E.; Sorensen, S. P.; Soumya, M.; Sourikova, I. V.; Sparks, N. A.; Staley, F.; Stankus, P. W.; Steinberg, P.; Stenlund, E.; Stepanov, M.; Ster, A.; Stoll, S. P.; Stone, M. R.; Sugitate, T.; Suire, C.; Sukhanov, A.; Sumita, T.; Sun, J.; Sziklai, J.; Tabaru, T.; Takagi, S.; Takagui, E. M.; Takahara, A.; Taketani, A.; Tanabe, R.; Tanaka, Y.; Taneja, S.; Tanida, K.; Tannenbaum, M. J.; Tarafdar, S.; Taranenko, A.; Tarján, P.; Tennant, E.; Themann, H.; Thomas, D.; Thomas, T. L.; Timilsina, A.; Todoroki, T.; Togawa, M.; Toia, A.; Tojo, J.; Tomášek, L.; Tomášek, M.; Tomita, Y.; Torii, H.; Towell, M.; Towell, R.; Towell, R. S.; Tram, V.-N.; Tserruya, I.; Tsuchimoto, Y.; Tsuji, T.; Utsunomiya, K.; Vale, C.; Valle, H.; van Hecke, H. W.; Vargyas, M.; Vazquez-Zambrano, E.; Veicht, A.; Velkovska, J.; Vértesi, R.; Vinogradov, A. A.; Virius, M.; Voas, B.; Vossen, A.; Vrba, V.; Vznuzdaev, E.; Wagner, M.; Walker, D.; Wang, X. R.; Watanabe, D.; Watanabe, K.; Watanabe, Y.; Watanabe, Y. S.; Wei, F.; Wei, R.; Wessels, J.; Whitaker, S.; White, S. N.; Winter, D.; Wolin, S.; Wood, J. P.; Woody, C. L.; Wright, R. M.; Wysocki, M.; Xia, B.; Xie, W.; Xue, L.; Yalcin, S.; Yamaguchi, Y. L.; Yamaura, K.; Yang, R.; Yanovich, A.; Yasin, Z.; Ying, J.; Yokkaichi, S.; Yoo, J. S.; Yoon, I.; You, Z.; Young, G. R.; Younus, I.; Yushmanov, I. E.; Zajc, W. A.; Zaudtke, O.; Zelenski, A.; Zhang, C.; Zhou, S.; Zimányi, J.; Zolin, L.

    2014-12-01

    We thank the staff of the Collider-Accelerator and Physics Departments at Brookhaven National Laboratory and the staff of the other PHENIX participating institutions for their vital contributions. We acknowledge support from the Office of Nuclear Physics in the Office of Science of the Department of Energy, the National Science Foundation, a sponsored research grant from Renaissance Technologies LLC, Abilene Christian University Research Council, Research Foundation of SUNY, and Dean of the College of Arts and Sciences, Vanderbilt University (USA), Ministry of Education, Culture, Sports, Science, and Technology and the Japan Society for the Promotion of Science (Japan), Conselho Nacional de Desenvolvimento Científico e Tecnológico and Fundação de Amparo à Pesquisa do Estado de São Paulo (Brazil), Natural Science Foundation of China, (People's Republic of China), Ministry of Science, Education, and Sports (Croatia), Ministry of Education, Youth and Sports (Czech Republic), Centre National de la Recherche Scientifique, Commissariat à l'Énergie Atomique, and Institut National de Physique Nucléaire et de Physique des Particules (France), Bundesministerium für Bildung und Forschung, Deutscher Akademischer Austausch Dienst, and Alexander von Humboldt Stiftung (Germany), OTKA NK 101 428 grant and the Ch. Simonyi Fund (Hungary), Department of Atomic Energy and Department of Science and Technology (India), Israel Science Foundation (Israel), National Research Foundation and WCU program of the Ministry Education Science and Technology (Republic of Korea), Physics Department, Lahore University of Management Sciences (Pakistan), Ministry of Education and Science, Russian Academy of Sciences, Federal Agency of Atomic Energy (Russia), VR and Wallenberg Foundation (Sweden), the US Civilian Research and Development Foundation for the Independent States of the Former Soviet Union, and the US-Israel Binational Science Foundation.

  11. Effect of Feeding On The Carbon and Oxygen Isotopic Composition In The Tissues and Skeleton of The Zooxanthellate Coral Stylophora Pistillata

    NASA Astrophysics Data System (ADS)

    Reynaud-Vaganay, S.; Ferrier-Pagès, C.; Sambrotto, R.; Juillet-Leclerc, A.; Jaubert, J.

    and J.-P. Gattuso4 1Centre Scientifique de Monaco, Avenue Saint Martin, MC-98000, Principality of Monaco 2Lamont-Doherty Earth Observatory, 61 Rt. 9W/ P.O. Box 1000, Palisades, NY 10964 U.S.A 3Laboratoire des Sciences du Climat et de l'Environnement, Laboratoire mixte CNRS- CEA, F-91180 Gif-sur-Yvette Cedex, France 4Observatoire Océanologique, Laboratoire d'Océanographie, CNRS-UPMC, BP 28, F- 06234 Villefranche-sur-mer Cedex, France The effect of feeding on the carbon isotopic composition of zooxanthellae, animal tissue and skeleton was investigated in the scleractinian coral Stylophora pistillata. Two sets of corals were grown with filtered seawater under controlled conditions. One group of colonies was fed with Artemia nauplii and compared to a control group that was starved. Fed corals exhibited higher concentrations of chlorophyll protein calcification rates than starved colonies. The net photosynthetic rate was higher in starved than in fed corals, whereas dark respiration was not significantly different. The average ? C value of Artemia nauplii used for feeding was -12. ? C was 13 13 significantly heavier in zooxanthellae than in animal tissues, for both fed (-10.1vs. -11.7) and starved colonies (-10.9vs. -13.2). Isotopic data reflected the incorporation of Artemia carbon into the coral tissue in that the ? C was 13 significantly heavier in fed than in starved colonies (-11.7 to -13.2 respectively), although there was no difference in the ? C of the zooxanthellae fraction. Skeletal 13 ? C was similar in fed and starved colonies (mean = -4.6). Skeletal ? O 13 18 composition was, however, significantly different between the two treatments (-4.24 to -4.05 for fed and starved colonies respectively). These data are used to establish a conceptual model of the carbon flow between the various compartments of a symbiotic coral.

  12. Meeting IYA Goals for Diverse Science Center and Planetarium Audiences

    NASA Astrophysics Data System (ADS)

    Nichols Yehling, Michelle; Carney, K.

    2008-05-01

    The International Year of Astronomy provides the Adler Planetarium in Chicago, IL with a chance to bring astronomy into the greater Chicagoland area. 1) The presenters will outline Adler's program plans to date, from community outreach programs such as Café Scientifique and citizen science light pollution observations, to programs within the institution, like a temporary exhibit about how telescopes have shaped our understanding of the cosmos. The presenters will focus on the range of programming and how this suite of programs brings together IYA topical threads, addressing sustainability and the needs of our audiences. 2) How do we know that the IYA programs we design actually work for our audiences? How do we assess and improve our work? This session will introduce participants to the "backwards design” process through which Adler educators create experiences that begin with focused goals. Facilitators will take participants through the Adler's evaluation planning method that uncovers what we want to know about our educational programs and experiences. Tools for program design and evaluation will be shared. 3) Facilitators will present for discussion three activities that have been designed and evaluated for one of our audiences, the museum-going family. Workshop participants are invited to critique and discuss these activities, their rationale, their fit with identified audience and institutional needs, and IYA thematic strands. Participants will share any ideas they have for adaptation of these activities for other audiences in their own settings. 4) Finally, all of the educational design and evaluation tools, program descriptions, and lesson plans will be compiled into an electronic document. Participants are encouraged to bring program description examples and/or activity lesson plans that can be incorporated into the document to provide an IYA "workbook". This workbook will be sent to all interested session participants by no later than July 31, 2008.

  13. Sharing is Winning: Cooperative Learning about Atmospheric Composition Change

    NASA Astrophysics Data System (ADS)

    Schuepbach, E.

    2010-09-01

    This contribution presents evolving good practice in disseminating the body of know-how, skills and competencies within the networked community of atmospheric scientists as established in ACCENT. The promotion of early-career scientists, and encouraging the next generation to move into the field were among the key issues addressed by the "Training and Education" programme in the European Network of Excellence in Atmospheric Composition Change (ACCENT). Dissemination avenues include a virtual knowledge train carrying the wealth of high-quality scientific learning material developed with experts involved in the ACCENT network. Learning opportunities on current research in atmospheric composition change in Europe were also created during face-to-face training workshops. Real-life examples of pressing air quality issues were addressed in meetings with stakeholder groups that offered opportunities for mutual learning in inspiring partnerships. In order to increase the expertise in atmospheric composition change across Europe, activities were organized with the general public (e.g., Café Scientifique), where the participating early-career scientists were confronted with questions from lay people. For interested teachers, didactic translations of compact overviews on air quality science topics developed in ACCENT offer links with the typical European science curriculum and go beyond school book content. Some of the educational events, methods and tools are described in a booklet published in 2009 ("We Care for Clean Air!", ISBN 978-88-95665-01-6). The electronic version and all training material can be downloaded from www.accent-network.org/portal/education - a valuable resource for teachers and learners around the globe.

  14. Homogeneous spectroscopic parameters for bright planet host stars from the northern hemisphere . The impact on stellar and planetary mass

    NASA Astrophysics Data System (ADS)

    Sousa, S. G.; Santos, N. C.; Mortier, A.; Tsantaki, M.; Adibekyan, V.; Delgado Mena, E.; Israelian, G.; Rojas-Ayala, B.; Neves, V.

    2015-04-01

    Aims: In this work we derive new precise and homogeneous parameters for 37 stars with planets. For this purpose, we analyze high resolution spectra obtained by the NARVAL spectrograph for a sample composed of bright planet host stars in the northern hemisphere. The new parameters are included in the SWEET-Cat online catalogue. Methods: To ensure that the catalogue is homogeneous, we use our standard spectroscopic analysis procedure, ARES+MOOG, to derive effective temperatures, surface gravities, and metallicities. These spectroscopic stellar parameters are then used as input to compute the stellar mass and radius, which are fundamental for the derivation of the planetary mass and radius. Results: We show that the spectroscopic parameters, masses, and radii are generally in good agreement with the values available in online databases of exoplanets. There are some exceptions, especially for the evolved stars. These are analyzed in detail focusing on the effect of the stellar mass on the derived planetary mass. Conclusions: We conclude that the stellar mass estimations for giant stars should be managed with extreme caution when using them to compute the planetary masses. We report examples within this sample where the differences in planetary mass can be as high as 100% in the most extreme cases. Based on observations obtained at the Telescope Bernard Lyot (USR5026) operated by the Observatoire Midi-Pyrénées and the Institut National des Science de l'Univers of the Centre National de la Recherche Scientifique of France (Run ID L131N11 - OPTICON_2013A_027).

  15. Vertical abundance stratification in the blue horizontal branch star HD 135485

    NASA Astrophysics Data System (ADS)

    Khalack, V. R.; Leblanc, F.; Bohlender, D.; Wade, G. A.; Behr, B. B.

    2007-05-01

    Context: It is commonly believed that the observed overabundances of many chemical species relative to the expected cluster metallicity in blue horizontal branch (BHB) stars appear as a result of atomic diffusion in the photosphere. The slow rotation of BHB stars (with T_eff > 11 500 K), typically v sin{i} < 10 km s-1, is consistent with this idea. Aims: In this work we search for observational evidence of vertical chemical stratification in the atmosphere of HD 135485. If this evidence exists, it will demonstrate the importance of atomic diffusion processes in the atmospheres of BHB stars. Methods: We undertake an extensive abundance stratification analysis of the atmosphere of HD 135485, based on recently acquired high resolution and S/N CFHT ESPaDOnS spectra and a McDonald-CE spectrum. Results: Our numerical simulations show that nitrogen and sulfur reveal signatures of vertical abundance stratification in the stellar atmosphere. It appears that the abundances of these elements increase toward the upper atmosphere. This fact cannot be explained by the influence of microturbulent velocity, because oxygen, carbon, neon, argon, titanium and chromium do not show similar behavior and their abundances remain constant throughout the atmosphere. It seems that the iron abundance may increase marginally toward the lower atmosphere. This is the first demonstration of vertical abundance stratification of metals in a BHB star. Based on observations made with ESPaDOnS at the Canada-France-Hawaii Telescope (CFHT) operated by the National Research Council (NRC) of Canada, the Institut des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) and the University of Hawaii and on observations made with Echelle Spectrograph on the McDonald Observatory 2.1-m Otto Struve Telescope. Full Table 2 is only available in electronic form at http://www.aanda.org

  16. Disclinations and grain boundary migration: evidence for a new deformation mechanism in olivine-rich rocks (Invited)

    NASA Astrophysics Data System (ADS)

    Cordier, P.; Demouchy, S. A.; Beausir, B.; Taupin, V.; Fressengeas, C.

    2013-12-01

    The rheology of olivine-rich rocks remains poorly understood. In particular, the ability of orthorhombic olivine to bear large strains represents an apparent violation of the von Mises criterion due to a lack of slip systems. In this study we show that a more general description of the deformation process including the motion of rotational defects referred to as disclinations can solve the olivine deformation paradox. Disclinations were proposed together with dislocations by Volterra (1907) to account for elastic distorsions (distorzione) in solids. They have recently been experimentally evidenced from orientation maps in several polycrystalline metallic alloys (Beausir & Fressengeas, 2013). Using high-resolution EBSD orientation maps we show that disclinations decorate grain boundaries in olivine samples deformed experimentally and in nature. We present a disclination-based model of a high-angle tilt boundary in olivine, which demonstrates that an applied shear induces grain boundary migration through disclination motion. This new approach allows further understanding of grain boundary-mediated plasticity in polycrystalline aggregates. By providing the missing mechanism for describing plastic flow in olivine, the present work allows multiscale modeling of the rheology of the upper mantle, from the atomic scale to the scale of the flow. Beausir, B. & Fressengeas, C., Disclination densities from EBSD orientation mapping. International Journal of Solids and Structures 50 (1), 137-146 (2013). Volterra, V., Sur l'équilibre des corps élastiques multiplement connexes. Annales scientifiques de l'École Normale Supérieure 24, 401-517 (1907). Acknowledgement for support: ERC grant RheoMan, Marie Curie fellowship PoEM and ANR NanoMec.

  17. Large scale silver nanowires network fabricated by MeV hydrogen (H+) ion beam irradiation

    NASA Astrophysics Data System (ADS)

    Honey, S.; Naseem, S.; Ishaq, A.; Maaza, M.; Bhatti, M. T.; Wan, D.

    2016-04-01

    A random two-dimensional large scale nano-network of silver nanowires (Ag-NWs) is fabricated by MeV hydrogen (H+) ion beam irradiation. Ag-NWs are irradiated under H+ ion beam at different ion fluences at room temperature. The Ag-NW network is fabricated by H+ ion beam-induced welding of Ag-NWs at intersecting positions. H+ ion beam induced welding is confirmed by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Moreover, the structure of Ag NWs remains stable under H+ ion beam, and networks are optically transparent. Morphology also remains stable under H+ ion beam irradiation. No slicings or cuttings of Ag-NWs are observed under MeV H+ ion beam irradiation. The results exhibit that the formation of Ag-NW network proceeds through three steps: ion beam induced thermal spikes lead to the local heating of Ag-NWs, the formation of simple junctions on small scale, and the formation of a large scale network. This observation is useful for using Ag-NWs based devices in upper space where protons are abandoned in an energy range from MeV to GeV. This high-quality Ag-NW network can also be used as a transparent electrode for optoelectronics devices. Project supported by the National Research Foundation of South Africa (NRF), the French Centre National pour la Recherche Scientifique, iThemba-LABS, the UNESCO-UNISA Africa Chair in Nanosciences & Nanotechnology, the Third World Academy of Science (TWAS), Organization of Women in Science for the Developing World (OWSDW), the Abdus Salam ICTP via the Nanosciences African Network (NANOAFNET), and the Higher Education Commission (HEC) of Pakistan.

  18. Gas Phase Absorption Spectroscopy of C+60 and C+70 in a Cryogenic Ion Trap: Comparison with Astronomical Measurements

    NASA Astrophysics Data System (ADS)

    Campbell, E. K.; Holz, M.; Maier, J. P.; Gerlich, D.; Walker, G. A. H.; Bohlender, D.

    2016-05-01

    Recent low-temperature laboratory measurements and astronomical observations have proved that the fullerene cation {{{C}}}60+ is responsible for four diffuse interstellar bands (DIBs). These absorptions correspond to the strongest bands of the lowest electronic transition. The gas phase spectrum below 10 {{K}} is reported here for the full wavelength range encompassed by the electronic transition. The absorption spectrum of {{{C}}}70+, with its origin band at 7959.2 {{\\mathringA }}, has been obtained under similar laboratory conditions. Observations made toward the reddened star {HD} 183143 were used in a specific search for the absorption of these fullerene cations in diffuse clouds. In the case of {{{C}}}60+, one further band in the astronomical spectrum at 9348.5 \\mathringA is identified, increasing the total number of assigned DIBs to five. Numerous other {{{C}}}60+ absorptions in the laboratory spectrum are found to lie below the astronomical detection limit. Special emphasis is placed on the laboratory determination of absolute absorption cross-sections. For {{{C}}}60+ this directly yields a column density, N({{{C}}}60+), of 2× {10}13 {{{cm}}}-2 in diffuse clouds, without the need to rely on theoretical oscillator strengths. The intensity of the {{{C}}}70+ electronic transition in the range 7000-8000 Å is spread over many features of similar strength. Absorption cross-section measurements indicate that even for a similar column density, the individual absorption bands of {{{C}}}70+ will be too weak to be detected in the astronomical spectra, which is confirmed giving an upper limit of 2 {{m\\mathringA }} to the equivalent width. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l’Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  19. [The international man-media Tessékéré (OHMi) Observatory: a research tool to study the complexity of arid ecosystems in Sahel].

    PubMed

    Guissé, Aliou; Boëtsch, Gilles; Ducourneau, Axel; Goffner, Deborah; Gueye, Lamine

    2013-01-01

    In the Sahelian zone, the drought phenomenon, combined with anthropic factors (monoculture, bush fires, defect or deficit of manure, overgrazing, etc.), has seriously affected ecological great balances, involving a degradation of the natural resources as well as a fall in agricultural productions, pointing to a process of desertification. To face these challenges, in the course of the 8th ordinary session of the conference of the Heads of States of the African Union held in January 2007 in Addis Ababa (Ethiopia), 11 countries adopted the Panafrican project called the Green Great Wall (GGW). The total objective of the GGW is to contribute i) to the fight against the desert's advance, ii) to the development of the Saharan-Sahelian zones toward a durable management of the natural resources, and iii) to the fight against poverty. It deals with the construction of a set of zones of afforestation crossing the whole African continent in the long term (7000km of which are in the west). Even if some decisions in the launching phase the GGW must be taken quickly, one cannot do without investment in interdisciplinary research. In particular, associating fundamental research and applied research will allow us to ensure the success in the medium and long term of such a large-scale reforestation project. Research segmented in compartmentalized knowledge fields needed to get adequate tools, among which OHMi Tessékéré, initiated by INNEE (Centre national de la recherche scientifique [CNRS]), in partnership with UCAD, constitutes an example. This suitable scientific tool, capable of action flexibility, of self-financing capacity, anchored in civil society, ready to implement a pragmatic and local interdisciplinarity founded currently on the concept of socio-ecological system (SES), is the one we chose to conduct our studies on the Ferlo arid ecosystems.

  20. International Congress on Transposable Elements (ICTE) 2012 in Saint Malo and the sea of TE stories

    PubMed Central

    2012-01-01

    An international conference on Transposable Elements (TEs) was held 21–24 April 2012 in Saint Malo, France. Organized by the French Transposition Community (GDR Elements Génétiques Mobiles et Génomes, CNRS) and the French Society of Genetics (SFG), the conference’s goal was to bring together researchers from around the world who study transposition in diverse organisms using multiple experimental approaches. The meeting drew more than 217 attendees and most contributed through poster presentations (117), invited talks and short talks selected from poster abstracts (48 in total). The talks were organized into four scientific sessions, focused on: impact of TEs on genomes, control of transposition, evolution of TEs and mechanisms of transposition. Here, we present highlights from the talks given during the platform sessions. The conference was sponsored by Alliance pour les sciences de la vie et de la santé (Aviesan), Centre national de la recherche scientifique (CNRS), Institut national de la santé et de la recherche médicale (INSERM), Institut de recherche pour le développement (IRD), Institut national de la recherche agronomique (INRA), Université de Perpignan, Université de Rennes 1, Région Bretagne and Mobile DNA. Chair of the organization committee Jean-Marc Deragon Organizers Abdelkader Ainouche, Mireille Bétermier, Mick Chandler, Richard Cordaux, Gaël Cristofari, Jean-Marc Deragon, Pascale Lesage, Didier Mazel, Olivier Panaud, Hadi Quesneville, Chantal Vaury, Cristina Vieira and Clémentine Vitte PMID:23110759

  1. The VIMOS Public Extragalactic Redshift Survey (VIPERS) . Galaxy clustering and redshift-space distortions at z ≃ 0.8 in the first data release

    NASA Astrophysics Data System (ADS)

    de la Torre, S.; Guzzo, L.; Peacock, J. A.; Branchini, E.; Iovino, A.; Granett, B. R.; Abbas, U.; Adami, C.; Arnouts, S.; Bel, J.; Bolzonella, M.; Bottini, D.; Cappi, A.; Coupon, J.; Cucciati, O.; Davidzon, I.; De Lucia, G.; Fritz, A.; Franzetti, P.; Fumana, M.; Garilli, B.; Ilbert, O.; Krywult, J.; Le Brun, V.; Le Fèvre, O.; Maccagni, D.; Małek, K.; Marulli, F.; McCracken, H. J.; Moscardini, L.; Paioro, L.; Percival, W. J.; Polletta, M.; Pollo, A.; Schlagenhaufer, H.; Scodeggio, M.; Tasca, L. A. M.; Tojeiro, R.; Vergani, D.; Zanichelli, A.; Burden, A.; Di Porto, C.; Marchetti, A.; Marinoni, C.; Mellier, Y.; Monaco, P.; Nichol, R. C.; Phleps, S.; Wolk, M.; Zamorani, G.

    2013-09-01

    We present the general real- and redshift-space clustering properties of galaxies as measured in the first data release of the VIPERS survey. VIPERS is a large redshift survey designed to probe in detail the distant Universe and its large-scale structure at 0.5 < z < 1.2. We describe in this analysis the global properties of the sample and discuss the survey completeness and associated corrections. This sample allows us to measure the galaxy clustering with an unprecedented accuracy at these redshifts. From the redshift-space distortions observed in the galaxy clustering pattern we provide a first measurement of the growth rate of structure at z = 0.8: fσ8 = 0.47 ± 0.08. This is completely consistent with the predictions of standard cosmological models based on Einstein gravity, although this measurement alone does not discriminate between different gravity models. Based on observations collected at the European Southern Observatory, Cerro Paranal, Chile, using the Very Large Telescope under programmes 182.A-0886 and partly 070.A-9007. Also based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. This work is based in part on data products produced at TERAPIX and the Canadian Astronomy Data Centre as part of the Canada-France-Hawaii Telescope Legacy Survey, a collaborative project of NRC and CNRS. The VIPERS web site is http://www.vipers.inaf.it/

  2. The VIMOS Public Extragalactic Redshift Survey (VIPERS). On the recovery of the count-in-cell probability distribution function

    NASA Astrophysics Data System (ADS)

    Bel, J.; Branchini, E.; Di Porto, C.; Cucciati, O.; Granett, B. R.; Iovino, A.; de la Torre, S.; Marinoni, C.; Guzzo, L.; Moscardini, L.; Cappi, A.; Abbas, U.; Adami, C.; Arnouts, S.; Bolzonella, M.; Bottini, D.; Coupon, J.; Davidzon, I.; De Lucia, G.; Fritz, A.; Franzetti, P.; Fumana, M.; Garilli, B.; Ilbert, O.; Krywult, J.; Le Brun, V.; Le Fèvre, O.; Maccagni, D.; Małek, K.; Marulli, F.; McCracken, H. J.; Paioro, L.; Polletta, M.; Pollo, A.; Schlagenhaufer, H.; Scodeggio, M.; Tasca, L. A. M.; Tojeiro, R.; Vergani, D.; Zanichelli, A.; Burden, A.; Marchetti, A.; Mellier, Y.; Nichol, R. C.; Peacock, J. A.; Percival, W. J.; Phleps, S.; Wolk, M.

    2016-04-01

    We compare three methods to measure the count-in-cell probability density function of galaxies in a spectroscopic redshift survey. From this comparison we found that, when the sampling is low (the average number of object per cell is around unity), it is necessary to use a parametric method to model the galaxy distribution. We used a set of mock catalogues of VIPERS to verify if we were able to reconstruct the cell-count probability distribution once the observational strategy is applied. We find that, in the simulated catalogues, the probability distribution of galaxies is better represented by a Gamma expansion than a skewed log-normal distribution. Finally, we correct the cell-count probability distribution function from the angular selection effect of the VIMOS instrument and study the redshift and absolute magnitude dependency of the underlying galaxy density function in VIPERS from redshift 0.5 to 1.1. We found a very weak evolution of the probability density distribution function and that it is well approximated by a Gamma distribution, independently of the chosen tracers. Based on observations collected at the European Southern Observatory, Cerro Paranal, Chile, using the Very Large Telescope under programmes 182.A-0886 and partly 070.A-9007. Also based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. This work is based in part on data products produced at TERAPIX and the Canadian Astronomy Data Centre as part of the Canada-France-Hawaii Telescope Legacy Survey, a collaborative project of NRC and CNRS. The VIPERS web site is http://www.vipers.inaf.it/

  3. Crosstalk: public cafés as places for knowledge translation concerning health care research.

    PubMed

    Reimer-Kirkham, Sheryl; Jule, Allyson

    2015-01-01

    This article explores the use of public cafés as a model for knowledge translation and community engagement. We base our discussion on a public café series organized around the theme of access to health care and held in three neighborhoods in the Lower Mainland of British Columbia, Canada. The cafés were part of the Canadian Institutes of Health Research Café Scientifique program. Our purposes for this series of cafés were threefold: (a) to provide a site of communication to connect research with members of the public, (b) to build a network among participants based on common connections to the local community, and (c) to explore through discussion how gendered and raced perspectives concerning access to health care may influence the lived experiences of Canadians today. We intended to promote an intergroup conversation, based on the assumption that people of First Nations descent, newcomers to Canada (whether through immigration or resettlement), and settlers (such as Euro-Canadians) would all benefit from hearing each other's perspectives on access to health care, as well as presentations by invited academics about their research on access to health care. A form of "crosstalk" emerged in the cafés, mediated by gender and ethnicity, where social differences and geographical distances between various groups were not easily bridged, and yet where opportunity was created for inclusive dialogic spaces. We conclude that knowledge translation is not easily accomplished with the café format, at least not with the type of critical knowledge we were aiming to translate and the depth of engagement we were hoping for. Our experiences highlighted three strategies that facilitate knowledge translation: relationships and shared goals; involvement of policymakers and decision makers; and tending to social relations of power.

  4. Resurrecting the red from the dead: optical properties of BCGs in X-ray luminous clusters

    NASA Astrophysics Data System (ADS)

    Bildfell, Chris; Hoekstra, Henk; Babul, Arif; Mahdavi, Andisheh

    2008-10-01

    We present measurements of surface brightness and colour profiles for the brightest cluster galaxies (BCGs) in a sample of 48 X-ray luminous galaxy clusters. These data were obtained as part of the Canadian Cluster Comparison Project (CCCP). The Kormendy relation of our BCGs is steeper than that of the local ellipticals, suggesting differences in the assembly history of these types of systems. We also find that while most BCGs show monotonic colour gradients consistent with a decrease in metallicity with radius, 25 per cent of the BCGs show colour profiles that turn bluer towards the centre (blue cores). We interpret this bluing trend as evidence for recent star formation. The excess blue light leads to a typical offset from the red sequence of 0.5 to 1.0mag in (g' - r'), thus affecting optical cluster studies that may reject the BCG based on colour. All of the blue-core BCGs are located within ~10kpc of the peak in the cluster X-ray emission. Furthermore, virtually all of the BCGs with recent star formation are in clusters that lie above the Lx-Tx relation. Based on photometry alone, these findings suggest that central star formation is a ubiquitous feature of BCGs in dynamically relaxed cool-core clusters. This implies that while active galactic nuclei (AGNs) and other heating mechanisms are effective at tempering cooling, they do not full compensate for the energy lost via radiation. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France and the University of Hawaii. E-mail: bildfell@uvic.ca (CB); hoekstra@uvic.ca (HH); babul@uvic.ca (AB); amahdavi@uvic.ca (AM) ‡ Alfred P. Sloan fellow.

  5. Evolution of the Frequency of Luminous (>=L*V) Close Galaxy Pairs at z < 1.2 in the COSMOS Field

    NASA Astrophysics Data System (ADS)

    Kartaltepe, J. S.; Sanders, D. B.; Scoville, N. Z.; Calzetti, D.; Capak, P.; Koekemoer, A.; Mobasher, B.; Murayama, T.; Salvato, M.; Sasaki, S. S.; Taniguchi, Y.

    2007-09-01

    We measure the fraction of luminous galaxies in pairs at projected separations of 5-20 kpc out to z=1.2 in the Cosmic Evolution Survey (COSMOS) field using ACS images and photometric redshifts derived from an extensive multiwavelength data set. Analysis of a complete sample of 106,188 galaxies more luminous than MV=-19.8 (~L*V) in the redshift range 0.1Scientifique de France, and the University of Hawaii.

  6. The VIMOS Public Extragalactic Redshift Survey (VIPERS). PCA-based automatic cleaning and reconstruction of survey spectra

    NASA Astrophysics Data System (ADS)

    Marchetti, A.; Garilli, B.; Granett, B. R.; Guzzo, L.; Iovino, A.; Scodeggio, M.; Bolzonella, M.; de la Torre, S.; Abbas, U.; Adami, C.; Bottini, D.; Cappi, A.; Cucciati, O.; Davidzon, I.; Franzetti, P.; Fritz, A.; Krywult, J.; Le Brun, V.; Le Fèvre, O.; Maccagni, D.; Małek, K.; Marulli, F.; Polletta, M.; Pollo, A.; Tasca, L. A. M.; Tojeiro, R.; Vergani, D.; Zanichelli, A.; Arnouts, S.; Bel, J.; Branchini, E.; Coupon, J.; De Lucia, G.; Ilbert, O.; Moutard, T.; Moscardini, L.; Zamorani, G.

    2017-03-01

    Context. Identifying spurious reduction artefacts in galaxy spectra is a challenge for large surveys. Aims: We present an algorithm for identifying and repairing spurious residual features in sky-subtracted galaxy spectra by using data from the VIMOS Public Extragalactic Redshift Survey (VIPERS) as a test case. Methods: The algorithm uses principal component analysis (PCA) applied to the galaxy spectra in the observed frame to identify sky line residuals imprinted at characteristic wavelengths. We further model the galaxy spectra in the rest-frame using PCA to estimate the most probable continuum in the corrupted spectral regions, which are then repaired. Results: We apply the method to 90 000 spectra from the VIPERS survey and compare the results with a subset for which careful editing was performed by hand. We find that the automatic technique reproduces the time-consuming manual cleaning in a uniform and objective manner across a large data sample. The mask data products produced in this work are released together with the VIPERS second public data release (PDR-2). based on observations collected at the European Southern Observatory, Cerro Paranal, Chile, using the Very Large Telescope under programs 182.A-0886 and partly 070.A-9007. Also based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA at the Canada-France-Hawaii Telescope (CFHT), that is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. This work is based in part on data products produced at TERAPIX and the Canadian Astronomy Data Centre as part of the Canada-France-Hawaii Telescope Legacy Survey, which is a collaborative project of NRC and CNRS. The VIPERS web site is http://www.vipers.inaf.it/.

  7. Testing the chemical tagging technique with open clusters

    NASA Astrophysics Data System (ADS)

    Blanco-Cuaresma, S.; Soubiran, C.; Heiter, U.; Asplund, M.; Carraro, G.; Costado, M. T.; Feltzing, S.; González-Hernández, J. I.; Jiménez-Esteban, F.; Korn, A. J.; Marino, A. F.; Montes, D.; San Roman, I.; Tabernero, H. M.; Tautvaišienė, G.

    2015-05-01

    Context. Stars are born together from giant molecular clouds and, if we assume that the priors were chemically homogeneous and well-mixed, we expect them to share the same chemical composition. Most of the stellar aggregates are disrupted while orbiting the Galaxy and most of the dynamic information is lost, thus the only possibility of reconstructing the stellar formation history is to analyze the chemical abundances that we observe today. Aims: The chemical tagging technique aims to recover disrupted stellar clusters based merely on their chemical composition. We evaluate the viability of this technique to recover co-natal stars that are no longer gravitationally bound. Methods: Open clusters are co-natal aggregates that have managed to survive together. We compiled stellar spectra from 31 old and intermediate-age open clusters, homogeneously derived atmospheric parameters, and 17 abundance species, and applied machine learning algorithms to group the stars based on their chemical composition. This approach allows us to evaluate the viability and efficiency of the chemical tagging technique. Results: We found that stars at different evolutionary stages have distinct chemical patterns that may be due to NLTE effects, atomic diffusion, mixing, and biases. When separating stars into dwarfs and giants, we observed that a few open clusters show distinct chemical signatures while the majority show a high degree of overlap. This limits the recovery of co-natal aggregates by applying the chemical tagging technique. Nevertheless, there is room for improvement if more elements are included and models are improved. Based on observations obtained at the Telescope Bernard Lyot (USR5026) operated by the Observatoire Midi-Pyrénées, Université de Toulouse (Paul Sabatier), Centre National de la Recherche Scientifique of France, and on public data obtained from the ESO Science Archive Facility under requests number 81252 and 81618.

  8. A Burger, a Beer, and a Side of Science

    NASA Astrophysics Data System (ADS)

    Wiehe, B. R.; Landsberg, R. H.; Wyatt, R. J.; Turner, M. S.

    2008-11-01

    Science cafés (a.k.a. café scientifiques) engage unconventional adult audiences and help researchers hone their communication skills in a relaxed and fun setting. Typically held in restaurants and pubs, science cafés provide a comfortable place for the public to speak with a scientist. National and local evaluations of the café format indicate that café are an effective way to engage adult audiences (especially non-scientists). Continued media coverage also demonstrates that something about them captures the public's imagination. This paper is based on an interactive oral presentation about organizing, presenting, and partnering with science café to bring IYA themes (and other current research) directly to new audiences. Real world examples from experienced café organizers and presenters provide an overview of what a science café is, how to start one, and how to use the format to draw attention to astronomy topics. The discussion includes suggestions for tapping into the existing national and international community of cafés (there are more than 60 in the U.S. alone), and information about free outreach resources. Break-out exercises in the original oral presentation were designed to help prepare participants to: find a suitable venue, advertise, work with café speakers, and foster the inclusive conversation that is the hallmark of a science café. Participants also learned about the impacts that can be expected from a science café, including benefits to audiences, café presenters, and hosting organizations. The overall goal of the original oral presentation was to stimulate a discussion about strategies for facilitating face-to-face communication between scientists and lay audiences.

  9. Science outreach on tap: insights and practices from three years ofDartmouth Science Pubs.

    NASA Astrophysics Data System (ADS)

    Hawley, R. L.; Serrell, N.; Tobery, C. E.; Riordan, S. A.

    2015-12-01

    The "Cafe Scientifique" (or "Science Cafe") has existed around theworld for decades. In an informal setting, one or more scientistsengage with a lay audience, typically over refreshments of some kind.These Science Cafes have taken many formats and taken place in manyvenues. Some feature a single presenter, some multiple; somecongregate in large venues, some small; some restrict the use of thepowerpoint slides, some do not.Our team at Dartmouth has hosted "Science Pubs" for three years. OurScience Pub takes place in a local pub, from 5-7pm on a weekday once amonth. We choose a theme for a pub and select three presenters. Thecomposition of our panel varies, but we generally have at least onefaculty member and one "less-academic" member, such as a town plannerwhen discussing hurricanes or an organic farmer when discussingpesticides. Often we include a graduate student in the panel. ThePub takes place in three "acts": 1) the presenters each give a briefintroduction to thier take on the topic, usually 10-15 minutes,extemporaneous with no slides, 2) the "wedding reception" phase, whichis a break during which the presenters circulate to the pub tables,answering questions and chatting with the attendees informally, and 3)reconvening for a more 'formal' question and answer period duringwhich the presenters answer questions from the audience.Here, we outline the format that makes up a Dartmouth Science Pub andshare insignts and lessons learned. Among many findings, we havelearned: 1) a group of three presenters makes for a lively discussion,as often presenters 'riff' off one another's points, 2) it is cruicalto have a facilitator, to 'run the show', freeing the sciencepresenters to concentrate on thier audience engagement, and 3) a shortmeeting ahead of time with the presenters is simple and very importantin creating a smooth event, and serves to help the presenters 'codeswitch' and adapt language, in lieu of a formal 'training'.

  10. Art & Astronomie - impressions celestes

    NASA Astrophysics Data System (ADS)

    Nazé, Yaël

    2015-10-01

    Ce livre revisite l'histoire de l'art dans ce qu'elle a de plus universel : son rapport au ciel. De l'Orient à l'Occident, de l'Antiquité à l'époque contemporaine, du classique au plus inattendu, il crée un espace singulier où se mêlent art et science, un musée imaginaire croisant sensibilité intime et compréhension du Cosmos, un jeu sans cesse réinventé...; car il n'y a pas une seule manière de regarder les étoiles. Bien sûr, le ciel possède un énorme pouvoir évocateur, une force inspiratrice à nulle autre pareille, mais l'inspiration n'est pas la seule des relations entre l'art et l'astronomie. En effet, les artistes peuvent apporter leur grain de sel aux révolutions scientifiques, tandis que l'astronomie peut aider à comprendre certaines œuvres. Avec près de 600 illustrations, cet ouvrage n'a pas pour but d'égrener la liste exhaustive des représentations de ciel étoilé, clair de lune, ambiance crépusculaire ou soleil de midi, mais plutôt d'aborder les multiples relations entre l'art et la science. Il s'agit d'une invitation à un voyage aux frontières mouvantes et incertaines des plus belles réalisations de l'esprit humain.

  11. Entrevue avec le Dr Charley Zeanah

    PubMed Central

    2013-01-01

    Le Dr Charles Zeanah est titulaire de la chaire de psychiatrie Mary K. Sellars-Polchow, professeur de pédiatrie clinique et vice-président de la pédopsychiatrie au département de psychiatrie et des sciences du comportement de la faculté de médecine de l’Université Tulane, à la Nouvelle-Orléans. Il est également directeur général de l’institut de la santé mentale des nourrissons et des jeunes enfants de Tulane. Il est récipiendaire de nombreux prix, notamment le prix de prévention Irving Phillips (AACAP), la mention élogieuse présidentielle pour sa recherche et son leadership exceptionnels en santé mentale des nourrissons (American Orthopsychiatric Association), le prix d’excellence clinique Sarah Haley Memorial (International Society for Traumatic Stress Studies), le prix de recherche en pédopsychiatrie Blanche F. Ittelson (APA), et le prix Serge Lebovici Award soulignant les contributions internationales à la santé mentale des nourrissons (World Association for Infant Mental Health). Le Dr Zeanah est fellow distingué de l’AACAP, fellow distingué de l’APA et membre du conseil d’administration de Zero to Three. Il est l’éditeur scientifique de Handbook of Infant Mental Health (3e édition) qui est considéré comme étant le manuel de pointe et la référence de base du domaine de la santé mentale des nourrissons.

  12. European Virtual Atomic And Molecular Data Center - VAMDC

    NASA Astrophysics Data System (ADS)

    Dimitrijevic, M. S.; Sahal-Brechot, S.; Kovacevic, A.; Jevremovic, D.; Popovic, L. C.

    2010-07-01

    Reliable atomic and molecular data are of great importance for different applications in astrophysics, atmospheric physics, fusion, environmental sciences, combustion chemistry, and in industrial applications from plasmas and lasers to lighting. Currently, very important resources of such data are highly fragmented, presented in different, nonstandardized ways, available through a variety of highly specialized and often poorly documented interfaces, so that the full exploitation of all their scientific worth is limited, hindering research in many topics like e.g. the characterization of extrasolar planets, understanding the chemistry of our local solar system and of the wider universe, the study of the terrestrial atmosphere and quantification of climate change; the development of the fusion rersearch, etc. The Virtual Atomic and Molecular Data Centre (http://www.vamdc.eu, VAMDC) is an European Union funded FP7 project aiming to build a secure, documented, flexible and interoperable e-science environment-based interface to existing atomic and molecular data. It will also provide a forum for training potential users and dissemination of expertise worldwide. Partners in the Consortium of the Project are: 1) Centre National de Recherche Scientifique - CNRS (Paris, Reims, Grenoble, Bordeaux, Dijon, Toulouse); 2) The Chancellor, Masters and Scholars of the University of Cambridge - CMSUC; 3) University College London - UCL; 4) Open University - OU; (Milton Keynes, England); 5) Universitaet Wien - UNIVIE; 6) Uppsala Universitet - UU; 7) Universitaet zu Koeln - KOLN; 8) Istituto Nazionale di Astrofisica - INAF (Catania, Cagliari); 9) Queen's University Belfast - QUB; 10) Astronomska Opservatorija - AOB (Belgrade, Serbia); 11) Institute of Spectroscopy RAS - ISRAN (Troitsk, Russia); 12) Russian Federal Nuclear Center - All-Russian Institute of Technical Physics - RFNC-VNIITF (Snezhinsk, Chelyabinsk Region, Russia; 13) Institute of Atmospheric Optics - IAO (Tomsk, Russia

  13. First Results from the Nearby Supernova Factory

    NASA Astrophysics Data System (ADS)

    Scalzo, R. A.; Aldering, G.; Lee, B. C.; Loken, S.; Nugent, P.; Perlmutter, S.; Siegrist, J.; Thomas, R. C.; Wang, L.; Wood-Vasey, W. M.; Adam, G.; Bacon, R.; Bonnaud, C.; Capoani, L.; Dubet, D.; Henault, F.; Lantz, B.; Lemonnier, J.-P.; Pecontal, A.; Pecontal, E.; Blanc, N.; Boudoul, G.; Bongard, S.; Castera, A.; Copin, Y.; Gangler, E.; Smadja, G.; Kessler, R.; Antilogus, P.; Astier, P.; Berrelet, E.; Garavini, G.; Gilles, S.; Guevara, L.-A.; Imbault, D.; Juramy, C.; Pain, R.; Taillet, R.; Vincent, D.; Baltay, C.; Rabinovitz, D.; Snyder, J.; Nearby Supernova Factory

    2004-12-01

    The Nearby Supernova Factory (SNfactory) is a project to discover, and study in detail, approximately 300 type Ia supernovae (SNe Ia) in the redshift range 0.03 < z < 0.08. Supernova candidates are found by searching wide-field imaging data from the Near Earth Asteroid Tracking (NEAT) project at JPL, and from the Palomar Consortium (Yale/JPL/Caltech); this ultimately produces a sample of supernovae which is unbiased with respect to host galaxy type. Follow-up observations are performed with the Supernova Integral Field Spectrograph (SNIFS), a novel instrument installed on the University of Hawaii 2.2-meter telescope on Mauna Kea and commissioned in April 2004. By providing time series of flux-calibrated optical spectra taken every two to three nights for each supernova, the SNfactory data set will dramatically improve our understanding of the physics of SNe Ia and reduce the uncertainties in their use as cosmological standard candles. SNIFS observations have been conducted remotely from the United States and France since June 2004, with increasing emphasis on scripting and automation for greater efficiency. This poster reviews the current status of SNIFS and of the SNfactory project and presents its first results after the commissioning of SNIFS. Support for SNfactory is provided in the United States by the DOE Office of Science, the National Science Foundation through the High Performance Wireless Research and Education Network (HPWREN), the Kavli Institute for Cosmological Physics (KICP), and the Gordon and Betty Moore Foundation, and in France by the Centre National de la Recherche Scientifique (CNRS) through the Institut National de Physique Nucleaire et de Physique des Particules (IN2P3), the Institut National des Sciences de l'Univers (INSU) and the Programme National de Cosmologie (PNC).

  14. Status of the Candidate Search for the Nearby Supernova Factory

    NASA Astrophysics Data System (ADS)

    Scalzo, R. A.; Aldering, G.; Aragon, C.; Bailey, S.; Bongard, S.; Bailey, S.; Kocevski, D.; Loken, S.; Nugent, P.; Perlmutter, S.; Thomas, R. C.; Wang, L.; Weaver, B. A.; Antilogus, P.; Gilles, S.; Pain, R.; Pereira, R.; Blanc, N.; Copin, Y.; Gangler, E.; Sauge, L.; Smadja, G.; Bonnaud, C.; Pecontal, E.; Kessler, R.; Baltay, C.; Rabinowitz, D.; Bauer, A.; Nearby Supernova Factory Collaboration

    2005-12-01

    The Nearby Supernova Factory (SNfactory) is a project to obtain time series spectrophotometry of a large sample of type Ia supernovae (SNe Ia) in the redshift range 0.03 < z < 0.08. To produce a sample of supernovae unbiased with respect to host galaxy type, SNfactory searches wide-field imaging data taken with the QUEST-II camera on the Samuel Oschin 1.2-m telescope on Mt. Palomar. The camera covers up to 500 square degrees per night to a depth of B = 21, and can be operated either in a point-and-track mode, as by the Near Earth Asteroid Tracking (NEAT) project at JPL, or in a drift-scan mode, as by the Palomar Consortium (Yale/JPL/Caltech). Promising candidates are screened, either photometrically (e.g. with the Nickel 1-meter telescope at Lick Observatory) or spectroscopically with the Supernova Integral Field Spectrograph (SNIFS) on the University of Hawaii 2.2-meter telescope on Mauna Kea (see Lee et al. poster, this session). In its current form, the search discovers some 25 spectroscopically confirmed SNe per month in the NEAT point-and-track data, of which 10-15 are typed as SNe Ia. We present a review of the status and performance of the search, and of future plans for expansion and improvement. Support for SNfactory is provided in the United States by the DOE Office of Science, the National Science Foundation through the High Performance Wireless Research and Education Network (HPWREN), the Kavli Institute for Cosmological Physics (KICP), and the Gordon and Betty Moore Foundation, and in France by the Centre National de la Recherche Scientifique (CNRS) through the Institut National de Physique Nucleaire et de Physique des Particules (IN2P3), the Institut National des Sciences de l'Univers (INSU) and the Programme National de Cosmologie (PNC).

  15. Avant Propos

    NASA Astrophysics Data System (ADS)

    Cornet, Alain; Broll, Norbert; Denier, Philippe

    2002-07-01

    Le quatrième colloque Rayons X et Matière (RX 2001) s'est tenu à Strasbourg du 4 au 7 décembre 2001. Comme lors des colloques précédents (1995, 1997 et 1999) nous avons pu réunir de nombreux chercheurs, industriels et constructeurs concernés par la caractérisation des matériaux. Cette manifestation qui se déroule tous les deux ans a pour objectifs de rendre compte périodiquement des avancées faites dans le domaine des techniques X et plus particulièrement de l'ingénierie des surfaces. Cette année nous avons ajouté deux nouveaux thèmes : étude des nanomatériaux et techniques des microfaisceaux. André GUINIER était avec nous lors du premier colloque (colloque 1995, consacré à la commémoration du centenaire de la découverte des rayons X). Nous sommes attristés par son décès et nous lui dédions le Colloque RX 2001. Les premiers articles de cet ouvrage rappellent sa vie de scientifique et ses principaux travaux. En même temps que nous écrivons ces quelques lignes, nous nous préparons à lancer le colloque RX 2003. Ces colloques ont lieu grâce à la participation constante des chercheurs et l'engagement des constructeurs et distributeurs de matériels ; nous les en remercions vivement et nous leur donnons rendez-vous à Strasbourg, en décembre 2003.

  16. Le transfert de connaissances entre les mathematiques et les sciences. Une etude exploratoire aupres d'eleves de 4e secondaire

    NASA Astrophysics Data System (ADS)

    Samson, Ghislain

    2003-06-01

    Au moment ou dans plusieurs pays on travaille a refondre les programmes d'etudes, tant au primaire qu'au secondaire, l'interet pour le transfert renait. Un des concepts fondamentaux en apprentissage consiste en l'habilete a reutiliser de facon consciente et efficace un acquis d'une situation a une autre situation. Cette recherche emane de preoccupations professionnelles au moment ou le chercheur etait enseignant au secondaire. Au cours de ces annees, il lui a ete possible de constater que plusieurs eleves percevaient difficilement les liens presents entre les disciplines mathematiques et scientifiques. Des travaux en psychologie cognitive et plus particulierement selon une perspective du traitement de l'information ont servi de cadre de reference pour evaluer et analyser les capacites de transfert aupres d'eleves de 4e secondaire. Ce cadre de reference permet de formuler le principal objectif qui est de mieux comprendre le processus de transfert chez des eleves en situation de resolution de problemes scientifiques. Cette these s'interesse donc au transfert en tant que phenomene important du processus d'apprentissage au sens de l'integration. La methode de recherche choisie, de nature qualitative, est principalement axee sur l'evaluation de la capacite a transferer des connaissances lors d'une epreuve et d'un entretien. Pour evaluer ce potentiel de transfert, nous avons elabore deux outils: une epreuve en mathematiques et en sciences et un guide d'entretien. Pour la passation de l'epreuve, le chercheur a pu compter sur la collaboration de 130 sujets provenant de deux ecoles. L'entretien complete la prise de donnees avec 13 sujets ayant accepte de poursuivre l'etude. Les donnees recueillies par ces instruments font ensuite l'objet d'une analyse de contenu. En premier lieu, les verbatims de l'epreuve et de l'entretien ont ete transcrits, puis codifies. La correction des reponses fournies pour les problemes resolus s'est faite a partir d'une grille d

  17. Mise à jour sur la prévention et le dépistage selon l’âge à l’intention des médecins de soins primaires canadiens

    PubMed Central

    Shimizu, Tawnya; Bouchard, Manon; Mavriplis, Cleo

    2016-01-01

    Résumé Objectif Faire la synthèse des meilleures lignes directrices fondées sur des données probantes concernant la prévention et le dépistage chez les adultes canadiens selon l’âge. Qualité des données Les recommandations du Groupe d’étude canadien sur les soins de santé préventifs représentent la source principale des renseignements et sont complétées par les recommandations pertinentes du Preventive Services Task Force des États-Unis lorsque celles du Groupe d’étude canadien étaient inaccessibles ou désuètes. Les guides de pratique des principales organisations nationales axées spécifiquement sur une maladie ou une spécialité ont aussi fait l’objet d’une révision pour prendre en compte les données factuelles les plus récentes. Message principal Les interventions de dépistage recommandées selon l’âge et le sexe sont présentées dans un tableau de synthèse où est mise en évidence la qualité des données à l’appui de ces recommandations. Un exemple de modèle à suivre dans les dossiers médicaux électroniques ou sur papier est aussi proposé. Conclusion Qu’il s’agisse d’une visite consacrée à la prévention ou d’une occasion saisie autrement de faire du counseling et du dépistage de prévention chez leurs patients, les médecins de soins primaires peuvent se servir de cette synthèse des recommandations fondées sur des données probantes pour maximiser leur efficience et prévenir d’importantes omissions ou des dépistages inutiles.

  18. Profil des diabétiques en hémodialyse chronique: étude multicentrique au Maroc

    PubMed Central

    Kabbali, Nadia; Mikou, Souad; El Pardiya, Nada Tazi; El Bardai, Ghita; Arrayhani, Mohamed; Houssaini, Tarik Sqalli

    2014-01-01

    Introduction Le diabète représente la première cause de mortalité par insuffisance rénale au Maroc. Sa prévalence selon l'Enquête Nationale sur la Population et la Santé Familiale de 2011 est de 3,3% [1]. Le but de ce travail est de déterminer la prévalence et d’étudier le profil clinique des diabétiques en hémodialyse chronique au Maroc. Méthodes Il s'agit d'une étude transversale multicentrique incluant 2066 hémodialysés chroniques dans les 39 centres d'hémodialyse de quatre régions marocaines. Résultats La prévalence du diabète en hémodialyse est 21,6%. L’âge moyen 59±13,2 ans (26-87). Le sex-ratio est de 1,9. L'IMC moyen est de 24,5 ± 4,4 kg/m2 (15-41). 42 patients sont porteurs d′une hépatite virale. La durée moyenne en HD est 39,3± 67 mois. 57% des patients gardent une diurèse résiduelle versus 43% chez les non diabétiques. Par rapport à ces derniers, nous avons noté plus d'HTA (64% versus 45%), plus de complications cardiovasculaires (23% versus 12%), un âge plus avancé à l'initiation de l'hémodialyse (55,5 versus 47 ans) et un taux de FAV proximales plus important. Conclusion La prévalence des diabétiques en hémodialyse est relativement élevée au Maroc sans tenir compte des patients qui ne bénéficient pas d’épuration extra-rénale pour des raisons socio-économiques. Le taux élevé de mortalité est imputable au retard et/ou à l'absence de la prise en charge néphrologique des diabétiques. Dans nos régions où le système sanitaire dispose de faible moyen, l'accent doit être mis sur le dépistage précoce de la néphropathie chez le diabétique. PMID:25374630

  19. [Use of intravenous iron supplementation in chronic kidney disease: Interests, limits, and recommendations for a better practice].

    PubMed

    Rottembourg, Jacques; Rostoker, Guy

    2015-12-01

    Iron deficiency is an important clinical concern in chronic kidney disease (CKD), giving rise to iron-deficiency anaemia, and various impaired cellular functions. Oral supplementation, in particular with ferrous salts, is associated with a high rate of gastro-intestinal side effects and is poorly absorbed, a problem that is avoided with intravenous (IV) irons. Recently, with the approval of the European Medicines Agency's Committee for Medicinal Products for Human Use, the French Agence nationale de sécurité du médicament et des produits de santé (ANSM) took adequate measures to minimize the risk of allergic reactions, by correction on the summary of intravenous iron products characteristics. All IV iron products should be prescribed, administered and injected, inside public or private hospitals exclusively, and a clinical follow-up after the infusion for at least 30 minutes is mandatory. The most stable intravenous iron complexes (low molecular weight iron dextran, ferric carboxymaltose, and iron isomaltoside 1000 [under agreement]) can be given in higher single doses and more rapidly than less recent preparations such as iron sucrose (originator or similars). Test doses are advisable for conventional low molecular weight iron dextrans, but are no more mandatory. Iron supplementation is recommended for all CKD patients with iron-deficiency anaemia and those who receive erythropoiesis-stimulating agents, whether or not they require dialysis. Intravenous iron is the preferred route of administration in haemodialysis patients, with randomized trials showing a significantly greater increase in haemoglobin levels for intravenous versus oral iron and a low rate of treatment-related adverse events during these trials. According ANSM, physicians should apply the product's label recommendations especially the posology. In the non-dialysis CKD population, the erythropoietic response is also significantly higher using intravenous versus oral iron, and tolerability is at

  20. Dealing with missing data in the Center for Epidemiologic Studies Depression self-report scale: a study based on the French E3N cohort

    PubMed Central

    2013-01-01

    Background The Center for Epidemiologic Studies - Depression scale (CES-D) is a validated tool commonly used to screen depressive symptoms. As with any self-administered questionnaire, missing data are frequently observed and can strongly bias any inference. The objective of this study was to investigate the best approach for handling missing data in the CES-D scale. Methods Among the 71,412 women from the French E3N prospective cohort (Etude Epidémiologique auprès des femmes de la Mutuelle Générale de l’Education Nationale) who returned the questionnaire comprising the CES-D scale in 2005, 45% had missing values in the scale. The reasons for failure to complete certain items were investigated by semi-directive interviews on a random sample of 204 participants. The prevalence of high depressive symptoms (score ≥16, hDS) was estimated after applying various methods for ignorable missing data including multiple imputation using imputation models with CES-D items with or without covariates. The accuracy of imputation models was investigated. Various scenarios of nonignorable missing data mechanisms were investigated by a sensitivity analysis based on the mixture modelling approach. Results The interviews showed that participants were not reluctant to answer the CES-D scale. Possible reasons for nonresponse were identified. The prevalence of hDS among complete responders was 26.1%. After multiple imputation, the prevalence was 28.6%, 29.8% and 31.7% for women presenting up to 4, 10 and 20 missing values, respectively. The estimates were robust to the various imputation models investigated and to the scenarios of nonignorable missing data. Conclusions The CES-D scale can easily be used in large cohorts even in the presence of missing data. Based on the results from both a qualitative study and a sensitivity analysis under various scenarios of missing data mechanism in a population of women, missing data mechanism does not appear to be nonignorable and estimates

  1. Air quality remote sensing over alpine regions with METEOSAT SEVIRI

    NASA Astrophysics Data System (ADS)

    Emili, E.; Popp, C.; Petitta, M.; Riffler, M.; Wunderle, S.

    2009-04-01

    It is well demonstrated that small aerosol particles or particulate matter (PM10 and PM2.5) affect air quality and can have severe effects on human's health. Hence, it is of great interest for public institutions to have an efficient PM monitoring network. In the last decades this data has been provided from ground-based instruments. Moreover, due to the fast development of space-borne remote sensing instruments, we can now be able to take advantage of air pollution measurements from space, which bears the potential to fill up the gap of spatial coverage from ground-based networks. This also improves the capability to assess air pollutants transport properties together with a better implementation in forecasting data assimilation procedures. In this study we examine the possibility of using data from the Spinning Enhanced Visible and Infrared Imager (SEVIRI), on-board of the geostationary Meteosat Second Generation (MSG) platform, to provide PM concentrations values over Switzerland. SEVIRI's high temporal resolution (15 minutes) could be very useful in investigating the daily behaviour of air pollutants and therefore be a good complement to measurements from polar orbiting sensors (e.g. MODIS). Switzerland is of particular interest because of its mountainous orography that hampers pollutants dispersion. Further, major transalpine connection routes, often characterised by high traffic load, act as a significant air pollution source. The south of Switzerland is also occasionally influenced by pollutants transported from the highly industrialised Po Valley in northern Italy. We investigate the existence of a linear relation between the SEVIRI retrieved AOD (Aerosol Optical Depth) and the PM concentration obtained from the ground-based air quality network NABEL (Nationales Beobachtungsnetz fuer Luftfremdstoffe). The temporal trend of this two quantities shows a significant relationship over various locations. The correlation coefficient is in some cases higher than 0

  2. Evaluation acousto-ultrasonique de l'endommagement thermique dans un materiau composite carbone/epoxyde

    NASA Astrophysics Data System (ADS)

    Beland, Sylvie

    1998-12-01

    Les materiaux composites avances a matrice polymerique lorsqu'utilises dans des applications structurales aerospatiales sont souvent exposes a des temperatures tres elevees durant de courtes periodes de temps. Ces expositions thermiques peuvent affecter de facon significative leurs proprietes mecaniques. Cette degradation des proprietes suite a la surchauffe est un probleme qui souleve de plus en plus d'inquietude au sein de la communaute aerospatiale. On s'interesse tout autant a la caracterisation de l'endommagement resultant de l'exposition thermique qu'a son evaluation non-destructive. Bien que la technique acousto-ultrasonique semble etre une technique d'evaluation non-destructive toute indiquee pour la detection et la caraterisation de l'endommagement thermique dans les composites avances, il semblerait qu'on ne l'ait pas encore exploitee en ce sens. Cette lacune combinee a l'engagement du Ministere canadien de la defense nationale a developper une technique d'evaluation non-destructive in-situ de l'endommagement thermique de structures composites dans certains avions de chasse de la flotte canadienne constituent la motivation majeure de ce projet de recherche. Cette etude evalue la capacite de la technique acousto-ultrasonique a detecter et quantifier l'endommagement subi par un materiau composite suite a une exposition thermique. Pour parvenir a cet objectif, l'approche de cette etude a ete principalement de nature experimentale. Dans ce contexte, une base importante de donnees acousto-ultrasoniques a ete generee sur des materiaux composites vierges et conditionnes dans le but de correler ces donnees a celles issues des essais mecaniques et des analyses micrographiques et fractographiques. L'evaluation acousto-ultrasonique de la degradation thermique a ete realisee sur des echantillons de resine pure et de composite ayant ete expose a divers conditionnements. De plus, l'evolution de l'endommagement dans des composites vierges et degrades thermiquement a ete

  3. Hail prevention by ground-based silver iodide generators: Results of historical and modern field projects

    NASA Astrophysics Data System (ADS)

    Dessens, J.; Sánchez, J. L.; Berthet, C.; Hermida, L.; Merino, A.

    2016-03-01

    The science of hail suppression by silver iodide (AgI) cloud seeding was developed during the second half of the 20th century in laboratory and tested in several research or operational projects using three delivery methods for the ice forming particles: ground generators, aircraft, and rockets. The randomization process for the seeding was often considered as the imperative method for a better evaluation but failed to give firm results, mostly because the projects did not last long enough considering the hazardous occurrence of severe hailfalls, and also probably due to the use of improper hail parameters. At the same time and until now, a continuous long-term research and operational field project (1952-2015) using ground generator networks has been conducted in France under the leadership of the Association Nationale d'Etude et de Lutte contre les Fléaux Atmosphériques (ANELFA), with a control initially based on annual insurance loss-to-risk ratios, then on hailpad data. More recently (2000-2009), a companion ground seeding project was developed in the north of Spain, with control mostly based on microphysical and hailpad data. The present paper, which focuses on hail suppression by ground seeding, reviews the production of the AgI nuclei, their dispersion and measurement in the atmosphere, as well as their observed or simulated effects in clouds. The paper summarizes the results of the main historical projects in Switzerland, Argentina, and North America, and finally concentrates on the current French and Spanish projects, with a review of already published results, complemented by new ones recently collected in Spain. The conclusion, at least for France and Spain, is that if ground seeding is performed starting 3 hours before the hail falls at the ground with a 10-km mesh AgI generator network located in the developing hailstorm areas, each generator burning about 9 g of AgI per hour, the hailfall energy of the most severe hail days is decreased by about 50%.

  4. Pharmacokinetics of rifampin and isoniazid in tuberculosis-HIV-coinfected patients receiving nevirapine- or efavirenz-based antiretroviral treatment.

    PubMed

    Bhatt, N B; Barau, C; Amin, A; Baudin, E; Meggi, B; Silva, C; Furlan, V; Grinsztejn, B; Barrail-Tran, A; Bonnet, M; Taburet, A M

    2014-06-01

    This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146-CARINEMO) trial, which assessed the pharmacokinetics of rifampin or isoniazid with or without the coadministration of nonnucleoside reverse transcriptase inhibitor-based HIV antiretroviral therapy in HIV-tuberculosis-coinfected patients in Mozambique. Thirty-eight patients on antituberculosis therapy based on rifampin and isoniazid participated in the substudy (57.9% males; median age, 33 years; median weight, 51.9 kg; median CD4(+) T cell count, 104 cells/μl; median HIV-1 RNA load, 5.5 log copies/ml). The daily doses of rifampin and isoniazid were 10 and 5 mg/kg of body weight, respectively. Twenty-one patients received 200 mg of nevirapine twice a day (b.i.d.), and 17 patients received 600 mg of efavirenz once a day (q.d.) in combination with lamivudine and stavudine from day 1 until the end of the study. Blood samples were collected at regular time-dosing intervals after morning administration of a fixed-dose combination of rifampin and isoniazid. When rifampin was administered alone, the median maximum concentration of drug in serum (Cmax) and the area under the concentration-time curve (AUC) at steady state were 6.59 mg/liter (range, 2.70 to 14.07 mg/liter) and 27.69 mg · h/liter (range, 11.41 to 109.75 mg · h/liter), respectively. Concentrations remained unchanged when rifampin was coadministered with nevirapine or efavirenz. When isoniazid was administered alone, the median isoniazid Cmax and AUC at steady state were 5.08 mg/liter (range, 1.26 to 11.51 mg/liter) and 20.92 mg · h/liter (range, 7.73 to 56.95 mg · h/liter), respectively. Concentrations remained unchanged when isoniazid was coadministered with nevirapine; however, a 29% decrease in the isoniazid AUC was observed when isoniazid was combined with efavirenz. The pharmacokinetic parameters of

  5. Assessment of the effectiveness and safety of Ethosuximide in the Treatment of non-Diabetic Peripheral Neuropathic Pain: EDONOT—protocol of a randomised, parallel, controlled, double-blinded and multicentre clinical trial

    PubMed Central

    Kerckhove, Nicolas; Mallet, Christophe; Pereira, Bruno; Chenaf, Chouki; Duale, Christian; Dubray, Claude; Eschalier, Alain

    2016-01-01

    Study Short Form 12 (MOS SF-12) and Leeds questionnaires). Ethics and communication The study was approved by an independent ethics committee (CPP Sud-Est VI, France, IRB00008526) and registered by the French competent authority (Agence nationale de sécurité du médicament (ANSM)). Trial registration number NCT02100046, Recruiting. PMID:27986742

  6. History of the treatment of scapula fractures.

    PubMed

    Bartonícek, Jan; Cronier, Patrick

    2010-01-01

    The history of treatment of scapula fractures is closely connected with the history of the French surgery. Paré (Les œuvres d´Ambroise Paré, conseiller, et premier chirurgien du Roy, Gabriel Buon, Paris, p VCV, 1579), Petit (Traité des maladies des os. Tome second, Charles-Etienne Hochereau, Paris, pp 122–138, 1723), Du Verney (Traité des maladies des os. Tome I, de Burre, Paris, pp 220–231, 1751) and Desault (Œuvres chirurgicales, ou tableau de la doctrine et de la pratique dans le traitement des maladies externes par Xav. Bichat, Desault, Méquignon, Devilliers, Deroi, Paris, pp 98–106, 1798) were the first to point out the existence of these fractures. The first drawing of a scapula fracture was presented by Vogt (Dissertatio de ambarum scapularum dextroeque simul claviculae fractura rara, Dissertatione Universitae Vitembergensi, Wittenberg, 1799). This author was also the first to describe the scapula fracture associated with ipsilateral fracture of the clavicle. The first radiograph of scapula fracture (glenoid fossa fracture) was published by Struthers (Edinburgh Med J 4(3):147–149, 1910). The first internal fixation of scapula fracture using plate was done by Lambotte (1910) who was followed by Lane (The operative treatment of fractures, Medical Publishing Co, London, pp 99–101, 1914) and later by Lenormant (Sur l´ostéosynthèse dans certains fractures de l´omoplate Bulletins et mémoires de la Société de chirgie de Paris, pp 1501–1502, 1923), Dujarier (Fracture du col chirgical de l´omoplate. Ostéosynthèse par plaque en T. Bonne réduction. Bulletin et mémoires de la Société de chirurgie de Paris, pp 1492–1493, 1923) and Basset (Ostéosynthèse d´une fracture de l´omoplate. Bulletin et mémoires de la Société nationale de chirurgie. p 193, 1924). Dupont and Evrard (J Chir (Paris) 39:528–534, 1932) presented the first detailed description of the surgical approach along the lateral border of the scapula including two

  7. Peripheral arterial obliterative disease. Cost of illness in France.

    PubMed

    Montron, A; Guignard, E; Pelc, A; Comte, S

    1998-01-01

    The main purpose of this study, carried out in 1995, was to determine, using available sources, the cost of peripheral arterial obliterative disease (PAOD) in France over a 1-year period. This cost-of-illness study was based on a retrospective analysis of the available literature and databases. It involved a description of epidemiological data and a cost estimate of the different medical resources consumed over 1 year. For this latter purpose, a payer perspective was chosen. Data were extracted from national representative surveys and databases with respect to morbidity and mortality [from the National Institute of Health and Medical Research (Institut National de la Santé et de la Recherche Médicale; INSERM) and the National Sickness Insurance Fund for Salaried People (Caisse Nationale d'Assurance Maladie des Travailleurs Salariés; CNAMTS)], consultations, examination tests and drug prescriptions [from the French Medical Audit conducted by Intercontinental Medical Statistics (IMS)], hospitalisations [from the Statistical Unit of the Department of Health-Service des Statistiques, des Etudes et des Systemes d'Information (SESI) and the National Public Research Centre in Health Economics (Centre de Recherche d'Etude et de Documentation en Economie de la Santé; CREDES)] and related health expenditure from CNAMTS. In France, the prevalence of stage II PAOD (Leriche and Fontaine classification) in 1992 was estimated to be 675,000; 53% of these patients had undergone vascular or bypass surgery. The total annual cost of healthcare (including consultations, drugs, laboratory tests, hospitalisation and hydrotherapy) for the management of patients with PAOD ranged from 3.9 billion French francs (F) to F4.6 billion (1995 values), depending on the type of hospital considered. 50% of this cost was related to hospitalisations and 75% was covered by the CNAMTS. Although this study was only a partial evaluation and did not take into account indirect costs or nonmedical direct

  8. TN International and ITS operational feedback regarding the decommissioning of obsolete casks dedicated to the transport and/or storage of nuclear raw materials, fuel and used fuel

    SciTech Connect

    Blachet, L.; Bimet, F.; Rennesson, N.

    2008-07-01

    Within the AREVA group, TN International is a major actor regarding the design of casks and transportation for the nuclear cycle. In the early 2005, TN International has started the project of decommissioning some of its own equipment and was hence the first company ever in the AREVA Group to implement this new approach. In order to do so, TN International has based this project by taking into account the AREVA Sustainable Development Charter, the French regulatory framework, the ANDRA (Agence Nationale pour la Gestion des Dechets Radioactifs - National Agency for the radioactive waste management) requirements and has deployed a step by step methodology such as radiological characterization following a logical route. The aim was to define a standardized process with optimized solutions regarding the diversity of the cask's fleet. As a general matter, decommissioning of nuclear casks is a brand new field as the nuclear field is more familiar with the dismantling of nuclear facilities and/or nuclear power plant. Nevertheless existing workshops, maintenance facilities, measurements equipments and techniques have been exploited and adapted by TN International in order to turn an ambitious project into a permanent and cost-effective activity. The decommissioning of the nuclear casks implemented by TN International regarding its own needs and the French regulatory framework is formalized by several processes and is materialized for instance by the final disposal of casks as they are or in ISO container packed with cut-off casks and big bags filled with crushed internal cask equipments, etc. The first part of this paper aims to describe the history of the project that started with a specific environmental analysis which took into account the values of AREVA as regards the Sustainable Development principles that were at the time and are still a topic of current concern in the world. The second part will deal with the definition, the design and the implementation of the

  9. Development of the Canadian Physiotherapy Assessment of Clinical Performance: A New Tool to Assess Physiotherapy Students' Performance in Clinical Education.

    PubMed

    Mori, Brenda; Brooks, Dina; Norman, Kathleen E; Herold, Jodi; Beaton, Dorcas E

    2015-08-01

    Objectif : Créer le premier projet d'outil canadien d'évaluation de la formation clinique des étudiants en physiothérapie. Phase 1: dégager un consensus sur les éléments constituants du nouvel outil, le nombre et l'emplacement des encadrés servant aux commentaires et l'échelle d'évaluation; Phase 2: explorer l'apparence et la validité du contenu du projet d'outil. Méthodes : On a utilisé, au cours de la Phase 1, la méthode Delphi et, au cours de la Phase 2, des entrevues cognitives menées auprès de nouveaux diplômés et de formateurs cliniques, ainsi que des entrevues détaillées menées auprès de spécialistes de l'éducation clinique et de la mesure. Résultats : On a dégagé un consensus sur la première version du nouvel outil au cours du cycle 3 du processus Delphi, que 21 participants ont terminé. On a réalisé des entrevues avec 13 formateurs cliniques, 6 nouveaux diplômés et 7 experts. Les nouveaux diplômés et les formateurs cliniques ont pu interpréter l'outil avec précision, qu'ils croyaient pouvoir appliquer à une expérience d'éducation clinique récente, et ont suggéré des améliorations. Les spécialistes ont fourni des conseils marquants. Conclusions : La première version d'un nouvel outil d'évaluation de la formation clinique des étudiants en physiothérapie, l'évaluation du rendement clinique (ERC) en physiothérapie canadienne, a été mis au point et fera l'objet d'autres améliorations et essais, y compris d'une consultation nationale des intervenants. Les données tirées de la Phase 2 contribueront à l'élaboration du module d'éducation en ligne.

  10. Evaluation des indicateurs d’alerte précoce de la résistance du VIH aux ARV en Côte d’Ivoire en 2011

    PubMed Central

    Yao, Kouadio Jean; Damey, Néto Florence; Konan, Diby Jean Paul; Aka, Joseph; Aka-Konan, Sandrine; Ani, Alex; Bonle, Marguerite Te; Kouassi, Dinard

    2016-01-01

    Introduction En 2001, l'Organisation des Nations Unies recommandait de rendre disponible les médicaments antirétroviraux dans les pays à ressources limitées. Cependant, l'utilisation de ces médicaments à grande échelle s'accompagne du développement de résistance du virus. En Côte d'Ivoire, plusieurs sites prescrivent les antirétroviraux. Cette étude avait pour objectif d'évaluer les facteurs programmatiques associés à un risque élevé d'émergence de résistance du VIH aux antirétroviraux. Méthodes Il s'agit d'une cohorte rétrospective sur 20 sites de prise en charge des personnes vivant avec le VIH. La population d'étude était constituée des personnes ayant initié leur traitement antirétroviral sur les sites en 2008-2009. L'estimation de la taille de l'échantillon a été faite à partir de la stratégie d'échantillonnage de l'OMS. Résultats Sur 20 sites, 98% des prescriptions initiales étaient conformes aux directives nationales et 20% des sites avaient 100% de prescriptions conformes. Au total, 33% des patients étaient perdus de vue au cours des 12 premiers mois de traitement antirétroviral et 20% des sites avaient moins de 20% de perdus de vue. A 12 mois, 51% des patients demeuraient sous traitement de première intention approprié et 11% des sites ont atteint le seuil d'au moins 70% de patients sous traitement de première intention approprié. Un seul site n'a pas connu de rupture d'antirétroviraux sur les 12 mois. Conclusion Des insuffisances relevées dans la prise en charge des personnes vivant avec le VIH traduisent l'existence d'un risque important de résistance du virus aux antirétroviraux en 2008-2009. Pour minimiser ce risque les pratiques de prescription devraient être améliorées, un système de recherche des absents aux rendez-vous devrait être mis en place et la disponibilité constante des antirétroviraux devraient être assurée. PMID:28250876

  11. Telemedicine: what framework, what levels of proof, implementation rules.

    PubMed

    Zannad, Faiez; Maugendre, Philippe; Audry, Antoine; Avril, Carole; Blaise, Lucile; Blin, Olivier; Burnel, Philippe; Falise-Mirat, Béatrice; Girault, Danièle; Giri, Isabelle; Goehrs, Jean-Marie; Lassale, Catherine; Le Meur, Roland; Leurent, Pierre; Ratignier-Carbonneil, Christelle; Rossignol, Patrick; Satonnet, Evelyne; Simon, Pierre; Treluyer, Laurent

    2014-01-01

    The concept of telemedicine was formalised in France in the 2009 "Hospital, patients, health territories" (loi hôpital, patients, santé, territoire) law and the 2010 decree through which it was applied. Many experiments have been carried out and the regulatory institutions (Ministry, Regional Health Agency [Agence régionale de santé, ARS], French National Health Authority [Haute autorité de santé, HAS], etc.) have issued various guidance statements and recommendations on its organisation and on the expectations of its evaluation. With this background, the round table wanted to produce recommendations on different areas of medical telemonitoring (the role of telemonitoring, the regulatory system, the principles for assessment, methods of use and conditions for sustained and seamless deployment). Whilst many studies carried out on new medical telemonitoring approaches have led to the postulate that it offers benefit, both clinically and in terms of patient quality of life, more information is needed to demonstrate its impact on the organisation of healthcare and the associated medico-economic benefit (criteria, methods, resources). Similarly, contractual frameworks for deployment of telemonitoring do exist, although they are complicated and involve many different stakeholders (Director General fo the Care Offering [Direction générale de l'offre de soins, DGOS], ARS, HAS, Agency for Shared Health Information Systems [Agence des systèmes d'information partagés de santé, ASIP], French National Data Protection Commission [Commission nationale informatique et libertés, CNIL], French National Medical Council [Conseil national de l'Ordre des médecins, CNOM], etc.) that would benefit from a shared approach and seamless exchange between the partners involved. The current challenge is also to define the conditions required to validate a stable economic model in order to promote organisational change. One topical issue is placing the emphasis on its evaluation and

  12. Characterization of a clay-rich rock through development and installation of specific hydrogeological and diffusion test equipment in deep boreholes

    NASA Astrophysics Data System (ADS)

    Delay, Jacques; Distinguin, Marc; Dewonck, Sarah

    Andra (Agence Nationale pour la Gestion des Déchets Radioactifs - National Radioactive Waste Management Agency) has developed specific tools and methodologies to evaluate and understand the main transport mechanisms of solute species in an argillaceous rock in the framework of the scientific program of the Meuse/Haute-Marne Underground Research Laboratory. This paper focuses on three specific equipments already installed in boreholes for the determination of convection and diffusion parameters in a very low permeability environment. The first one is a specific borehole completion for head and permeability measurements with an integrated wireless telemetry device. In 1995, Andra devised a probe equipped with a pressure sensor to monitor the long-term evolution of electro-magnetically transmitted pore pressures. The data gathered by this first device, and a second one installed in 2001, have shown the occurrence of overpressures in very low permeability formations. The second device is derived from the multipacker system used for monitoring the drainage of the Oxfordian limestone due to the sinking of the shaft above the Callovo-Oxfordian. It is used for obtaining from a single borehole, a pressure profile of the argillaceous formation and its encasing units. To date, the major information obtained with these two borehole equipments is the existence of a 25-35 m anomalous excess hydraulic head in the 130 m thick Callovo-Oxfordian argillaceous formation. Head values in the argillaceous rock exceed those in the overlying Oxfordian limestone by 25-35 m, and those in the underlying Dogger by over 45 m. The third equipment described in the paper, is derived from the experiment carried out at the Mont Terri rock laboratory since 1996 for the characterization of diffusion and retention processes. The system is adapted for a borehole drilled from the surface. The objectives of this experiment are as follows: Verification of the predominant role played by molecular diffusion

  13. Implementation of Theeuropeanwater Framework Directive In France: New Challenges For River Basin Organisat Ion, Planning and Participation

    NASA Astrophysics Data System (ADS)

    Allain, S.

    defined and implemented by a new tripartite entity, the Commission Locale de l'Eau (CLE : Local Water Commission), which can be considered as a real river basin organisation; an empirical analysis of the implementation of such a procedure can offer therefore many new insights and the paper will present the results of an analysis of 10 case studies. But it will be also necessary to put such an experience side by side with the political will to develop public debates and to extend the roles of the Commission Nationale du Débat Public ("Public Debate National Commission").

  14. Behaviour of nuclides and U-series disequilibrium in clayey sediments: application to the Late Jurassic record from the eastern Paris basin

    NASA Astrophysics Data System (ADS)

    Casanova, J.; Négrel, Ph.; Innocent, C.; Brulhet, J.

    2003-04-01

    We present a record of U-series disequilibrium covering the Callovo-Oxfordian-Thitonian times of the Late Jurassic carbonated platform from the eastern part of the Paris basin. The Callovo-Oxfordian clayey layer is the potential host rock for reconnaissance work carried out by Andra (e.g., Agence Nationale de Gestion des Déchets Radioactifs) in eastern France, the objective of which is the designing and building of an underground research laboratory to study the aptitude of the clay-marl Callovo-Oxfordian layer for the storage of radioactive wastes. We analyse U and Th trace elements on both the labile fraction (extracted by cold HCl) and the total bulk sediments. The Th contents are extremely low in the Oxfordian shelf reef carbonates (<10 ppb) with respect to the Kimmeridgian-Tithonian clayey marls and the Callovian-Oxfordian argilites (up to 10 ppm). In contrast, the uranium contents are much more homogenous (1 ppm ±0.8) along the section. With respect to bulk concentrations, the nuclide contents in the labile component are particularly low in the Callovian-Oxfordian argilites. This behaviour suggests that given the extremely low permeability of the rock, any groundwater circulation of solutes could only have taken place by diffusion - a very slow mechanism that favours water-rock interactions. For U-series analyses (measured by alpha-spectrometry), a total of 43 bulk-rock samples were preferentially microdrilled from the fine-grained lithologies, although the heterogeneity of carbonate facies within sections necessitated occasional sampling of coarser grained lithologies. Within the carbonate-rich part (Oxfordian to Tithonian) of the section, the 234U/238U ratios slightly fluctuate from secular equilibrium and are interpreted as preferential 234U-solution processes related to groundwater circulation. Preferential removal of 234U in this zone is also indicated by some 230Th/234U activity ratios higher than unity. In contrast, most of the samples from the

  15. Séroprévalence de l’AgHBs chez la femme enceinte dans le centre du Maroc

    PubMed Central

    Sbiti, Mohammed; Khalki, Hanane; Benbella, Imane; louzi, Lhoussaine

    2016-01-01

    La transmission materno-fœtale du virus de l'hépatite B (VHB) est un problème qui préoccupe toujours les autorités sanitaires à travers le monde et suscite la mise en place de mesures préventives renforcées. Le statut réplicatif du virus chez la mère séropositive, évalué par la positivité de l'AgHbe et le taux de la charge virale, conditionne le risque de contamination qui est plus important en période péri-natale. Les mères porteuses chroniques du VHB constituent un véritable réservoir de la transmission verticale de cette infection. Nous avons étudié, à travers cette enquête sur 1120 femmes enceintes Marocaines, la séroprévalence de l'AgHBs qui était de 2,35%, dans le but d'alimenter les données nationales sur ce sujet. Parmi ces femmes séropositives pour l'AgHBs, 79,1% avaient un AgHBe négatif et ont bénéficié d'une recherche moléculaire qui s'est révélée positive dans 89,4% des cas. La vaccination de la femme en âge de procréer est l'un des piliers majeurs de la prévention de la transmission verticale du VHB, seulement 2,4% de nos patientes étaient vaccinées. Ceci relève l'intérêt du dépistage au cours de la grossesse, qui doit se focaliser sur la sensibilisation à la vaccination de femmes séronégatives, et le suivi par biologie moléculaire des mères séropositives dans le but d'instaurer un traitement prophylactique adéquat. PMID:27795784

  16. Fixedwing UAV soundings of the boundary layer during the ScaleX 2015 summer campaign in southern Germany

    NASA Astrophysics Data System (ADS)

    Philipp, Andreas; Groos, Alexander; Petersen, Erik; Bischoff, Julian; Szogs, Sebastian; Beck, Christoph; Hähner, Jörg; Jacobeit, Jucundus

    2016-04-01

    In order to examine the potential to close the local water cycle budget and to evaluate models on different scales (among other aims) a fleet of 6 fixed wing UAVs has been operated by the Institute for Geography and the Institute for Informatics of the University of Augsburg during the ScaleX measurement campaign of the KIT/IMK-IFU (Karlsruher Institut für Technologie/Institut für Meteorologie und Klimatologie, Garmisch Partenkirchen). The site is located in southern Germany in a rural, hilly landscape at a small catchment tributing to the Ammersee and equipped with several ground based and remote sensing hydrological instruments. In order to complement these instruments by in situ measurements of the boundary layer, three intensive observation periods (IOPs) for taking temperature and humidity profiles took place, each with a different set up in order to evaluate optimal operation modes. The UAVs are all operated by the open hardware Apogee autopilot and sensor controller developed by ENAC (Ecole Nationale de l'Aviation Civile, Toulouse) operated by the PPRZ open source software package. The first IOP (30.06.-01.07.2015) was an experiment to cover a small site of 500 by 500 meters (well-apointed with hydrological instruments) in a 24 hours period as dense as possible. Thus three simultaneous helical profile flights (radius 70 m) have been run at each full hour around three different centres with heights ranging up to 1000 m above ground level (with special permissions). During a second IOP (15.07.2015) it has been tried to increase the frequence of profile flights up to 2 flights per hours between 7:30 and 14:00 CEST. These soundings have been accompanied by flyovers of a manned ultra light aircraft of the IMK-IFU. Finally a third experiment (06.08.2015) tried to evaluate longer flights (up to 55 minutes) of two UAVs at constant levels of 300 and 500 m above ground level between 6:00 and 14:00 CEST in order to cover the early diurnal cycle even more constantly

  17. Long Period (LP) volcanic earthquake source location at Merapi volcano by using dense array technics

    NASA Astrophysics Data System (ADS)

    Metaxian, Jean Philippe; Budi Santoso, Agus; Laurin, Antoine; Subandriyo, Subandriyo; Widyoyudo, Wiku; Arshab, Ghofar

    2015-04-01

    Since 2010, Merapi shows unusual activity compared to last decades. Powerful phreatic explosions are observed; some of them are preceded by LP signals. In the literature, LP seismicity is thought to be originated within the fluid, and therefore to be representative of the pressurization state of the volcano plumbing system. Another model suggests that LP events are caused by slow, quasi-brittle, low stress-drop failure driven by transient upper-edifice deformations. Knowledge of the spatial distribution of LP events is fundamental for better understanding the physical processes occurring in the conduit, as well as for the monitoring and the improvement of eruption forecasting. LP events recorded at Merapi have a spectral content dominated by frequencies between 0.8 and 3 Hz. To locate the source of these events, we installed a seismic antenna composed of 4 broadband CMG-6TD Güralp stations. This network has an aperture of 300 m. It is located on the site of Pasarbubar, between 500 and 800 m from the crater rim. Two multi-parameter stations (seismic, tiltmeter, S-P) located in the same area, equipped with broadband CMG-40T Güralp sensors may also be used to complete the data of the antenna. The source of LP events is located by using different approaches. In the first one, we used a method based on the measurement of the time delays between the early beginnings of LP events for each array receiver. The observed differences of time delays obtained for each pair of receivers are compared to theoretical values calculated from the travel times computed between grid nodes, which are positioned in the structure, and each receiver. In a second approach, we estimate the slowness vector by using MUSIC algorithm applied to 3-components data. From the slowness vector, we deduce the back-azimuth and the incident angle, which give an estimation of LP source depth in the conduit. This work is part of the Domerapi project funded by French Agence Nationale de la Recherche (https

  18. Pharmacokinetics of Rifampin and Isoniazid in Tuberculosis-HIV-Coinfected Patients Receiving Nevirapine- or Efavirenz-Based Antiretroviral Treatment

    PubMed Central

    Bhatt, N. B.; Barau, C.; Amin, A.; Baudin, E.; Meggi, B.; Silva, C.; Furlan, V.; Grinsztejn, B.; Barrail-Tran, A.; Bonnet, M.

    2014-01-01

    This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146-CARINEMO) trial, which assessed the pharmacokinetics of rifampin or isoniazid with or without the coadministration of nonnucleoside reverse transcriptase inhibitor-based HIV antiretroviral therapy in HIV-tuberculosis-coinfected patients in Mozambique. Thirty-eight patients on antituberculosis therapy based on rifampin and isoniazid participated in the substudy (57.9% males; median age, 33 years; median weight, 51.9 kg; median CD4+ T cell count, 104 cells/μl; median HIV-1 RNA load, 5.5 log copies/ml). The daily doses of rifampin and isoniazid were 10 and 5 mg/kg of body weight, respectively. Twenty-one patients received 200 mg of nevirapine twice a day (b.i.d.), and 17 patients received 600 mg of efavirenz once a day (q.d.) in combination with lamivudine and stavudine from day 1 until the end of the study. Blood samples were collected at regular time-dosing intervals after morning administration of a fixed-dose combination of rifampin and isoniazid. When rifampin was administered alone, the median maximum concentration of drug in serum (Cmax) and the area under the concentration-time curve (AUC) at steady state were 6.59 mg/liter (range, 2.70 to 14.07 mg/liter) and 27.69 mg · h/liter (range, 11.41 to 109.75 mg · h/liter), respectively. Concentrations remained unchanged when rifampin was coadministered with nevirapine or efavirenz. When isoniazid was administered alone, the median isoniazid Cmax and AUC at steady state were 5.08 mg/liter (range, 1.26 to 11.51 mg/liter) and 20.92 mg · h/liter (range, 7.73 to 56.95 mg · h/liter), respectively. Concentrations remained unchanged when isoniazid was coadministered with nevirapine; however, a 29% decrease in the isoniazid AUC was observed when isoniazid was combined with efavirenz. The pharmacokinetic parameters of

  19. Seasonal forecasting for water resource management: the example of CNR Genissiat dam on the Rhone River in France

    NASA Astrophysics Data System (ADS)

    Dommanget, Etienne; Bellier, Joseph; Ben Daoud, Aurélien; Graff, Benjamin

    2014-05-01

    Compagnie Nationale du Rhône (CNR) has been granted the concession to operate the Rhone River from the Swiss border to the Mediterranean Sea since 1933 and carries out three interdependent missions: navigation, irrigation and hydropower production. Nowadays, CNR generates one quarter of France's hydropower electricity. The convergence of public and private interests around optimizing the management of water resources throughout the French Rhone valley led CNR to develop hydrological models dedicated to discharge seasonal forecasting. Indeed, seasonal forecasting is a major issue for CNR and water resource management, in order to optimize long-term investments of the produced electricity, plan dam maintenance operations and anticipate low water period. Seasonal forecasting models have been developed on the Genissiat dam. With an installed capacity of 420MW, Genissiat dam is the first of the 19 CNR's hydropower plants. Discharge forecasting at Genissiat dam is strategic since its inflows contributes to 20% of the total Rhone average discharge and consequently to 40% of the total Rhone hydropower production. Forecasts are based on hydrological statistical models. Discharge on the main Rhone River tributaries upstream Genissiat dam are forecasted from 1 to 6 months ahead thanks to multiple linear regressions. Inputs data of these regressions are identified depending on river hydrological regimes and periods of the year. For the melting season, from spring to summer, snow water equivalent (SWE) data are of major importance. SWE data are calculated from Crocus model (Météo France) and SLF's model (Switzerland). CNR hydro-meteorological forecasters assessed meteorological trends regarding precipitations for the next coming months. These trends are used to generate stochastically precipitation scenarios in order to complement regression data set. This probabilistic approach build a decision-making supports for CNR's water resource management team and provides them with

  20. High time to use rapid tests to detect multidrug resistance in sputum smear-negative tuberculosis in Belarus.

    PubMed

    Rusovich, V; Kumar, A M V; Skrahina, A; Hurevich, H; Astrauko, A; de Colombani, P; Tayler-Smith, K; Dara, M; Zachariah, R

    2014-12-21

    Contexte : Le Belarus (Europe de l'Est) est confronté à une épidémie de tuberculose multirésistante (TB-MDR). En 2012, les patients atteints de tuberculose pulmonaire (TBP) à frottis positif ont bénéficié en priorité de diagnostics moléculaires pour confirmer une TB-MDR, tandis que les patients atteints de TBP à frottis négatif (SN-PTB) ont bénéficié de méthodes conventionnelles qui retardaient souvent le diagnostic de TB-MDR de 2 à 4 mois.Objectif : Déterminer la proportion de TB-MDR parmi les patients SN-PTB enregistrés en 2012, ainsi que les facteurs cliniques et démographiques associés.Schéma : Etude de cohorte rétrospective basée sur des données émanant de tout le pays grâce au registre électronique national de la TB.Résultats : Sur 5377 cas de TB enregistrés, 2960 (55%) étaient des SN-PTB. Parmi ces derniers, 1639 (55%) avaient une culture positive, dont 768 (47%) avaient une TB-MDR : 33% (363/1084) nouveaux cas et 73% (405/555) patients déjà traités préalablement. La notion de traitement antérieur, l'âge, la région, la résidence en milieu urbain, le statut à l'égard du virus de l'immunodéficience humaine et le fait d'être retraité étaient indépendamment associés à la TB-MDR.Conclusion : Près de la moitié des patients SN-PTB à culture positive ont une TB-MDR, et dans les cas de retraitement, on arrive à plus de sept patients sur dix. La décision politique nationale d'extension des diagnostics moléculaires rapides à tous les patients TBP, y compris les patients SN-PTB, semble donc justifiée. Il est nécessaire de prendre des mesures afin d'assurer la mise en œuvre de cette priorité urgente, en raison des implications d'un diagnostic retardé à la fois pour les patients et en termes de santé publique.

  1. Screening difficult-to-reach populations for tuberculosis using a mobile medical unit, Punjab India.

    PubMed

    Binepal, G; Agarwal, P; Kaur, N; Singh, B; Bhagat, V; Verma, R P; Satyanarayana, S; Oeltmann, J E; Moonan, P K

    2015-12-21

    Contexte : En Inde, la Mission nationale santé a fourni une unité médicale mobile (MMU) par district dans l'état du Penjab afin d'offrir des services de soins de santé primaires aux populations difficilement accessibles.Objectifs : Déterminer le nombre de patients présumés atteints de la tuberculose (TB) et le nombre de cas de TB détectés et traités parmi les patients qui ont utilisé les services de la MMU de mai à décembre 2012 dans le district de Mohali de l'état du Penjab, Inde.Méthodes : Une étude transversale a été réalisée et l'étude des registres des consultations, du laboratoire, de la radiologie et des services de TB de la MMU a permis de compter le nombre de personnes présumées atteintes de TB et le nombre de personnes ayant eu un diagnostic de TB.Résultats : Un total de 8346 patients ont fréquenté la MMU, dont 663 (8%) avaient des symptômes suggérant une TB. Parmi ces derniers, 540 (81%) ont bénéficié d'une recherche de TB pulmonaire grâce à un examen de l'expectoration ou à une radiographie pulmonaire. Au total, 58 (11%) patients ont eu des preuves cliniques ou biologiques de TB pulmonaire, dont 21 (36%) ont mis en route un traitement de la tuberculose.Conclusion : Comme les MMU font partie intégrante du système de santé publique général, ces unités ont le potentiel de détecter les cas de TB parmi les populations « difficiles à atteindre ». De plus amples recherches sont requises afin d'optimiser le diagnostic de la TB dans les MMU pour accélérer la mise en route du traitement de la TB.

  2. Leiomyosarcome de la langue: à propos d'un cas

    PubMed Central

    El jahd, Lahcen; Barhmi, Ismail; Tazi, Nabil; Rouadi, Sami; Abada, Reda; Roubal, Mohammed; janah, Abdelaziz; Mahtar, Mohammed

    2015-01-01

    Le léiomyosarcome primitif de la langue est une tumeur rare qui se développe aux dépens des fibres musculaires lisses. Le diagnostic est souvent difficile, fondé sur des caractéristiques immuno-histologiques particulières. L'objectif de ce travail est de décrire le profil épidémiologique, clinique, thérapeutique et évolutif du léiomyosarcome à travers un cas et une revue de la littérature. Nous rapportons le cas d'un homme âgé de 26 ans, sans antécédents pathologique particuliers, consultant pour une tuméfaction de la langue mobile évoluant depuis 2 ans. Une biopsie de la masse a été réalisée. L’étude anatomopathologique et immunohistochimique a confirmé le diagnostic d'un léiomyosarcome de la langue. L'IRM de la langue a objectivé un processus lesionnel intéressant la portion mobile et antérieur de la langue. Une exérèse de la masse a été réalisée. L'examen histologique a montré la présence d'un large néoplasme de 6 cm compatible à un léiomyosarcome peu différencié de la langue, de garde II selon la Fédération Nationale des Centres de Lutte Contre le Cancer (FNCLCC). Une radiothérapie externe sur la cavité buccale avec une dose de 65 Gy a été réalisée. Le patient a présenté 2 mois après la fin du traitement une adénopathie latéro-cervicale haute gauche (territoire II), il a bénéficié d'un curage ganglionnaire fonctionnel intéressant les territoires I, II et III puis réadressé en radiothérapie. Le léiomyosarcome de la langue est très rare surtout chez le sujet jeune. La chirurgie et la radiothérapie sont les armes thérapeutiques majeures. Le pronostic est très mauvais, Les facteurs les plus importants sont les marges d'exérèse et le grade. PMID:26600908

  3. [Silicosis in Switzerland. A half century of observation. The physician's viewpoint].

    PubMed

    Maillard, J M; Zufferey, R; Fellmann, E

    1983-01-01

    In Switzerland, the first cases of silicosis were recorded by Zangger in 1900. Since 1930, patients with silicosis have been provided with certain services by the "Caisse Nationale Suisse d'Assurances" (i.e. Swiss National Insurance Fund), an organization enforcing the Occupational Accidents and Diseases Bill. However, it took another two years before an effectively organized struggle against silicosis was started. Eventually, by 1938, this specific pneumoconiosis was acknowledged as an occupational disease under Swiss Law. Thus, the CNSA has been concerned with this disease for half a century, and it seems relevant now to take stock of the situation. From 1930 to late 1980, 9690 cases of silicosis were accepted by the CNSA. Nearly one half (46%) of these silicotic patients were still alive on December 31, 1980; another third had died of silicosis and the rest of other affections not related The origin of cases has remained remarkably constant over the course of time. Underground working and the stone-working industry account for the majority of cases (70%), followed by smelting works (16%) and the ceramic industry (5%). The remaining 9% are due to various causes. Silicosis hazards have declined but still remain real. In late 1980, 1287 companies in Switzerland were being monitored from this standpoint. More than two-thirds (67%) belong to the stone-working industry (even though only 30% of hazard-exposed workers are employed in this sector), 10% are involved in underground work (10% of hazard-exposed workers), 10% are smelting industries (36% exposed) and 6% belong to the ceramic industry (17% exposed). Since 1950, the number of hazard-exposed people has fluctuated between relatively narrow limits (i.e. 15,000 and 20,000). Corresponding figures for previous periods are not known. Some facts indicate that silicosis is becoming less problematic: a) The annual incidence rate of silicosis in Switzerland has evolved in three distinct phases. From 1930 to 1940 the

  4. Opinion of the Scientific Committee on Consumer Safety (SCCS) - Revision of the opinion on o-Phenylphenol, Sodium o-phenylphenate and Potassium o-phenylphenate (OPP), in cosmetic products.

    PubMed

    Scientific Committee On Consumer Safety Sccs; Bernauer, Ulrike

    2016-08-01

    o-Phenylphenol, Sodium o-phenylphenate, Potassium o-phenylphenate, CAS n. 90-43-7, 132-27-4, 13707-65-8 as preservatives are regulated in Annex V/7 of the Cosmetics Regulation (EC) n. 1223/2009 at a maximum concentration of 0.2% (as phenol). In February 2013, the Commission received a risk assessment submitted by the French Agency ANSM (Agence nationale de sécurité des médicaments et des produits de santé) which rose concerns about the use of o-Phenylphenol as preservatives in cosmetic products. In the context of the ANSM report (Evaluation du risque lié à l'utilisation de l'orthophénylphénol CAS n. 90-43-7 dans les produits cosmétiques) o-Phenylphenol has been identified as likely to be an endocrine disruptor. The report concludes that the maximum authorised concentration (currently of 0.2%) of o-Phenylphenol for use as a preservative should be revised due to low margin of safety. In January 2014, in response to a call for data on o-Phenylphenol by the Commission, Industry submitted a safety dossier in order to defend the current use of o-Phenylphenol, Sodium o-phenylphenate, Potassium o-phenylphenate, CAS n. 90-43-7, 132-27-4, 13707- 65-8 as preservatives in cosmetic formulations at a maximum concentration of 0.2% (as phenol). o-Phenylphenol as preservative with a maximum concentration of 0.2% in leave-on cosmetic products is not safe. Also, in view of further exposures including noncosmetic uses (see Anses, 2014), the maximum concentration of o-Phenylphenol in leave-on cosmetic products should be lowered. However, the proposed maximum use concentration of up to 0.15% by the applicant can be considered safe. The use of o-Phenylphenol as preservative with a maximum concentration of 0.2% in rinse-off cosmetic products is considered safe. Based on the information provided, no conclusions of safe use can be drawn for Sodium o-phenylphenate and Potassium o-phenylphenate. In vitro data indicate an absent or very weak binding affinity of OPP to the oestrogen

  5. Médecine des voyages

    PubMed Central

    Aw, Brian; Boraston, Suni; Botten, David; Cherniwchan, Darin; Fazal, Hyder; Kelton, Timothy; Libman, Michael; Saldanha, Colin; Scappatura, Philip; Stowe, Brian

    2014-01-01

    Résumé Objectif Définir la pratique de la médecine des voyages, présenter les éléments fondamentaux d’une consultation complète préalable aux voyages à des voyageurs internationaux et aider à identifier les patients qu’il vaudrait mieux envoyer en consultation auprès de professionnels de la médecine des voyages. Sources des données Les lignes directrices et les recommandations sur la médecine des voyages et les maladies liées aux voyages publiées par les autorités sanitaires nationales et internationales ont fait l’objet d’un examen. Une recension des ouvrages connexes dans MEDLINE et EMBASE a aussi été effectuée. Message principal La médecine des voyages est une spécialité très dynamique qui se concentre sur les soins préventifs avant un voyage. Une évaluation exhaustive du risque pour chaque voyageur est essentielle pour mesurer avec exactitude les risques particuliers au voyageur, à son itinéraire et à sa destination et pour offrir des conseils sur les interventions les plus appropriées en gestion du risque afin de promouvoir la santé et prévenir les problèmes médicaux indésirables durant le voyage. Des vaccins peuvent aussi être nécessaires et doivent être personnalisés en fonction des antécédents d’immunisation du voyageur, de son itinéraire et du temps qu’il reste avant son départ. Conclusion La santé et la sécurité d’un voyageur dépendent du degré d’expertise du médecin qui offre le counseling préalable à son voyage et les vaccins, au besoin. On recommande à ceux qui donnent des conseils aux voyageurs d’être conscients de l’ampleur de cette responsabilité et de demander si possible une consultation auprès de professionnels de la médecine des voyages pour tous les voyageurs à risque élevé.

  6. Cathode-less gridded ion thrusters for small satellites

    NASA Astrophysics Data System (ADS)

    Aanesland, Ane

    2016-10-01

    diameter unit well adapted for a CubeSat or SmallSat mission. This work was supported by Agence Nationale de la Recherche under contract ANR-11-IDEX-0004-02 (Plas@Par) and by SATT Paris-Saclay.

  7. Monitoring and analysis of the change process in curriculum mapping compared to the National Competency-based Learning Objective Catalogue for Undergraduate Medical Education (NKLM) at four medical faculties. Part I: Conducive resources and structures

    PubMed Central

    Lammerding-Koeppel, Maria; Giesler, Marianne; Gornostayeva, Maryna; Narciss, Elisabeth; Wosnik, Annette; Zipfel, Stephan; Griewatz, Jan; Fritze, Olaf

    2017-01-01

    Objective: After passing of the National Competency-based Learning Objectives Catalogue in Medicine (Nationaler Kompetenzbasierter Lernzielkatalog Medizin, [NKLM, retrieved on 22.03.2016]), the German medical faculties must take inventory and develop their curricula. NKLM contents are expected to be present, but not linked well or sensibly enough in locally grown curricula. Learning and examination formats must be reviewed for appropriateness and coverage of the competences. The necessary curricular transparency is best achieved by systematic curriculum mapping, combined with effective change management. Mapping a complex existing curriculum and convincing a faculty that this will have benefits is not easy. Headed by Tübingen, the faculties of Freiburg, Heidelberg, Mannheim and Tübingen take inventory by mapping their curricula in comparison to the NKLM, using the dedicated web-based MERLIN-database. This two-part article analyses and summarises how NKLM curriculum mapping could be successful in spite of resistance at the faculties. The target is conveying the widest possible overview of beneficial framework conditions, strategies and results. Part I of the article shows the beneficial resources and structures required for implementation of curriculum mapping at the faculties. Part II describes key factors relevant for motivating faculties and teachers during the mapping process. Method: The network project was systematically planned in advance according to steps of project and change management, regularly reflected on and adjusted together in workshops and semi-annual project meetings. From the beginning of the project, a grounded-theory approach was used to systematically collect detailed information on structures, measures and developments at the faculties using various sources and methods, to continually analyse them and to draw a final conclusion (sources: surveys among the project participants with questionnaires, semi-structured group interviews and

  8. Comparative study of the hail suppression efficiency in Bulgaria and in France

    NASA Astrophysics Data System (ADS)

    Simeonov, P.

    A partir des données normalisées des assurances grêle, on mesure l'efficacité de la lutte contre la grêle de deux expériences différentes en employant un test bivariable habituellement utilisé pour détecter une dérive dans des séries chronologiques pluviométriques. La première expérience est le programme opérationnel bulgare qui met en oeuvre la méthode soviétique d'ensemencement par fusées dans huit régions, appelées polygones, du nord-ouest et du sud de la Bulgarie; l'autre expérience est le programme français développé par l'Association Nationale d'Etude et de Lutte contre les Fléaux Atmosphériques (ANELFA) qui utilise des générateurs au sol de noyaux d'iodure d'argent fonctionnant avant et pendant le développement des orages à grêle. Les données utilisées pour le test sont les pourcentages annuels de pertes aux récoltes dans les zones cibles et contrôles avant et pendant les années d'ensemencement. Lorsqu'un changement de tendance est décelé dans la cible en comparaison de la zone de contrôle, le test bivariable indique la date du changement, son niveau de signification statistique ainsi que son taux. Pour chacun des deux programmes, on trouve une diminution significative des dommages par la grêle dans les zone ensemencées, et la période de cette diminution correspond au développement des activités de suppression de la grêle dans les deux pays.

  9. Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial

    PubMed Central

    2014-01-01

    Background Although reperfusion injury has been shown to be responsible for cardiomyocytes death after an acute myocardial infarction, there is currently no drug on the market that reduces this type of injury. TRO40303 is a new cardioprotective compound that was shown to inhibit the opening of the mitochondrial permeability transition pore and reduce infarct size after ischemia-reperfusion in a rat model of cardiac ischemia-reperfusion injury. Methods In the rat model, the therapeutic window and the dose effect relationship were investigated in order to select the proper dose and design for clinical investigations. To evaluate post-ischemic functional recovery, TRO40303 was tested in a model of isolated rat heart. Additionally, TRO40303 was investigated in a Phase I randomized, double-blind, placebo controlled study to assess the safety, tolerability and pharmacokinetics of single intravenous ascending doses of the compound (0.5 to 13 mg/kg) in 72 healthy male, post-menopausal and hysterectomized female subjects at flow rates from 0.04 to 35 mL/min (EudraCT number: 2010-021453-39). This work was supported in part by the French Agence Nationale de la Recherche. Results In the vivo model, TRO40303 reduced infarct size by 40% at 1 mg/kg and by 50% at 3 and 10 mg/kg given by intravenous bolus and was only active when administered before reperfusion. Additionally, TRO40303 provided functional recovery and reduced oxidative stress in the isolated rat heart model. These results, together with pharmacokinetic based allometry to human and non-clinical toxicology data, were used to design the Phase I trial. All the tested doses and flow rates were well tolerated clinically. There were no serious adverse events reported. No relevant changes in vital signs, electrocardiogram parameters, laboratory tests or physical examinations were observed at any time in any dose group. Pharmacokinetics was linear up to 6 mg/kg and slightly ~1.5-fold, hyper-proportional from 6 to 13

  10. A Canadian survey of postgraduate education in Aboriginal women's health in obstetrics and gynaecology.

    PubMed

    Jumah, Naana Afua; Wilson, Don; Shah, Rajiv

    2013-07-01

    Objectif : Évaluer les connaissances des résidents canadiens en obstétrique-gynécologie en matière de santé des femmes autochtones (SFA) et leur expérience dans ce domaine (y compris une auto-évaluation de la compétence), et déterminer la capacité des directeurs de programme de résidence d’offrir un curriculum en SFA et d’évaluer les ressources disponibles en vue de soutenir cette initiative. Méthodes : Des sondages destinés aux résidents et aux directeurs de programme ont été distribués dans tous les programmes de résidence agréés en obstétrique-gynécologie du Canada. Le sondage destiné aux résidents comptait 20 questions à choix multiple couvrant quatre domaines clés : connaissances générales au sujet des peuples autochtones du Canada; les effets du système de pensionnat; l’expérience clinique en SFA; et une auto-évaluation de la compétence en SFA. Le sondage destiné aux directeurs de programme comptait une évaluation du contenu du curriculum en SFA et des ressources disponibles en vue de soutenir ce curriculum. Résultats : Les résidents détiennent peu de connaissances préalables au sujet de la SFA et des déterminants de la santé, et sont conscients de ces lacunes. Ils s’intéressent à la SFA et reconnaissent l’importance de pouvoir disposer d’une formation dans ce domaine pour leurs activités professionnelles à venir. Les directeurs de programme soutiennent l’élaboration d’un curriculum en SFA, mais ne détiennent pas les ressources nécessaires pour offrir un curriculum exhaustif dans ce domaine et tireraient avantage de la disponibilité d’un curriculum standardisé. Conclusion : La mise sur pied d’une initiative nationale en ce qui concerne l’élaboration d’un curriculum pourrait constituer une façon efficace de faciliter l’offre d’une formation en SFA, tout en atténuant la nécessité pour chacun des programmes de chercher à obtenir des ressources à cette fin.

  11. Navigating the maze of requirements for obtaining approval of non-interventional studies (NIS) in the European Union.

    PubMed

    Ramirez, Isabelle

    2015-01-01

    Ziel: Dieser Artikel soll über die Komplexität und unerwartete regulatorische Anforderungen bei multinationalen und multizentrischen, nicht-interventionellen Studien (NIS) in der Europäischen Union aufklären.Methoden: Die Internetseiten der zuständigen nationalen Behörden, Ethikkommissionen (EK) und Datenschutzbehörden wurden konsultiert, um Vorschriften und Richtlinien zum Genehmigungsverfahren von NIS in den verschiedenen Mitgliedstaaten der EU zu finden.Ergebnis: Viele zusätzliche Hürden wurden identifiziert, die weder offengelegt noch deutlich in den jeweiligen Verordnungen/Richtlinien für NIS beschrieben waren. Obwohl die Genehmigung durch die nationale Behörde für NIS grundsätzlich nicht erforderlich ist, wird in vielen Ländern dennoch empfohlen die geplante NIS – vor dem EK-Antrag – der nationalen Behörde anzuzeigen, um die Bestätigung zu erhalten, dass die geplante NIS nicht in die Kategorie „interventionelle Studie“ fällt. Zudem ist in einigen Ländern eine Probandenversicherung erforderlich. In vielen Ländern, in denen multizentrische NIS geplant sind, bedarf es zusätzlich zur Zustimmung der zentralen Ethikkommission auch noch die zustimmende Bewertung aller lokalen Ethikkommissionen, denn ein zentrales EK-Gutachten wird nicht als ausreichend betrachtet. Die Anforderungen an EK-Dokumente und an Gebühren für die Einreichung variieren stark unter allen Mitgliedsstaaten. Zusätzliche Genehmigungen von den Datenschutzbehörden und Versicherungsgesellschaften sind in einigen Ländern einzuholen.Schlussfolgerung: Das Genehmigungsverfahren für multizentrische und multinationale NIS ist zeitaufwendig, vor allem wegen des Mangels an Transparenz und den unterschiedlichen regulatorischen Anforderungen der Mitgliedsstaaten. Die EU-Rechtsvorschriften zur Pharmakovigilanz und die neue EU-Verordnung Nr. 536/2014 über klinische Studien sind zwar ein Schritt nach vorn bei der Schaffung eines Rechtsrahmens für PASS (post-authorisation safety

  12. Genotypic resistance profiles of HIV-2-treated patients in West Africa

    PubMed Central

    Charpentier, Charlotte; Eholié, Serge; Anglaret, Xavier; Bertine, Mélanie; Rouzioux, Christine; Avettand-Fenoël, Véronique; Messou, Eugène; Minga, Albert; Damond, Florence; Plantier, Jean-Christophe; Dabis, François; Peytavin, Gilles; Brun-Vézinet, Françoise; Ekouevi, Didier K.

    2014-01-01

    Objective To assess the virological response, genotypic resistance profiles, and antiretroviral plasma concentrations in HIV-2 antiretroviral-treated (antiretroviral therapy, ART) patients in Côte d‘Ivoire. Methods A cross-sectional survey was conducted among HIV-2 patients receiving ART. Plasma HIV-2 viral load was performed using the Agence Nationale de Recherche sur le SIDA et les hépatites virales (ANRS) assay. Protease and reverse transcriptase sequencing was performed using in-house methods and antiretroviral plasma concentrations were assessed using ultra performance liquid chromatography combined with tandem mass spectrometry. Results One hundred and forty-five HIV-2-treated patients were enrolled with a median CD4+ cell count of 360 cells/µl (interquartile range, IQR = 215–528). Median duration of ART was 4 years (IQR = 2–7) and 74% of patients displayed viral load less than 50 copies/ml. Median plasma HIV-2 RNA among patients with viral load more than 50 copies/ml was 3016 copies/ml (IQR = 436–5156). Most patients (84%) received a lopinavir/ritonavir-based regimen. HIV-2 resistance mutations to nucleoside reverse transcriptase inhibitors and protease inhibitors were detected in 21 of 25 (84%) and 20 of 29 (69%) samples, respectively. The most prevalent nucleoside reverse transcriptase inhibitor resistance mutations were M184I/V (90%), Q151M (24%), and S215F/Y (24%). The most prevalent protease inhibitor resistance mutations were V47A (60%) and I54M (30%). Median CD4+ cell counts were 434 cells/µl (292–573) and 204 cells/µl (122–281) in patients with viral load less than 50 copies/ml and those exhibiting virological failure (P < 0.0001), respectively. The proportions of patients with adequate antiretroviral plasma concentrations were 81 and 93% in patients displaying virological failure and in those with viral load less than 50 copies/ml, respectively (P = 0.046), suggesting good treatment adherence. Conclusion We observed adequate drug

  13. Interprofessional practice in health care: an educational project with four learning sequences for students from six study programs.

    PubMed

    Nowak, Anna Christina; Klimke-Jung, Kathrin; Schäfer, Thorsten; Reif, Karl

    2016-01-01

    Einleitung: Vor dem Hintergrund des demographischen Wandels und der Zunahme komplexer Versorgungsanforderungen fordern nationale und internationale Organisationen eine verstärkte Kooperation der Gesundheitsberufe. Die Implementierung von interprofessionellen Lehrangeboten in die Studiengänge der medizinischen, geburtshilflichen, pflegerischen und therapeutischen Berufe ist noch selten. Derzeit werden in Deutschland erste Projekte erprobt. Im vorliegenden Artikel werden die Prozesserfahrungen der Organisatoren bei der Implementierung gemeinsamer interprofessioneller Lehrangebote für sechs Studiengänge dargestellt. Projektbeschreibung: Im Rahmen des Kooperationsprojekts „Interprofessionelles Handeln im Gesundheitswesen“ zwischen der Medizinischen Fakultät der Ruhr-Universität Bochum und dem Department für Angewandte Gesundheitswissenschaften der Hochschule für Gesundheit wurden interprofessionelle Lerneinheiten entwickelt, implementiert und evaluiert mit dem Ziel, langfristige curriculare Ausbildungsstrukturen zwischen den beiden Hochschulen zu etablieren. In vier Lernsequenzen standen die Vermittlung von kommunikativen Kompetenzen, das Wissen und die Wertschätzung gegenüber den Tätigkeitsbereichen der anderen Gesundheitsberufe sowie die Reflexion der eigenen beruflichen Rolle und Verantwortungsbereiche im Vordergrund. Dazu arbeiteten die Studierenden in interprofessionellen Kleingruppen zusammen.Ergebnisse: Insgesamt haben 220 Studierende der Ergotherapie, der Hebammenkunde, der Logopädie, der Medizin, der Pflege und der Physiotherapie an interprofessionellen Kleingruppenseminaren teilgenommen. Bei der Durchführung und Implementierung der Lehrveranstaltungen zeigten sich insbesondere strukturelle und methodische Herausforderungen, die bei der zukünftigen Entwicklung interprofessioneller Lehrangebote berücksichtigt werden sollten. Hierzu zählen die curriculare Einbettung, gemeinsame Zeiträume in den Stundenplänen und räumliche Ressourcen f

  14. The physics, performance and predictions of the PEGASES ion-ion thruster

    NASA Astrophysics Data System (ADS)

    Aanesland, Ane

    2014-10-01

    . This work received financial state aid managed by the Agence Nationale de la Recherche under the reference ANR-2011-BS09-40 (EPIC) and ANR-11-IDEX-0004-02 (Plas@Par).

  15. An Evaluation Model for a Multidisciplinary Chronic Pelvic Pain Clinic: Application of the RE-AIM Framework.

    PubMed

    Chen, Innie; Money, Deborah; Yong, Paul; Williams, Christina; Allaire, Catherine

    2015-09-01

    Objectif : La douleur pelvienne chronique (DPC) est un trouble prévalent, débilitant et coûteux. Bien que des lignes directrices nationales et des données empiriques soutiennent l’utilisation d’un modèle de soins multidisciplinaires pour les patientes qui présentent des DPC, les cliniques canadiennes offrant un tel modèle sont peu nombreuses. Le BC Women’s Centre for Pelvic Pain and Endometriosis a été créé pour répondre à ce besoin et un intérêt a été manifesté à l’endroit des effets de ce modèle de soins sur le fardeau de la maladie en Colombie-Britannique. Nous avons cherché à créer une approche envers son évaluation en utilisant le cadre de référence RE-AIM (Reach, Efficacy, Adoption, Implementation, Maintenance) pour déterminer les effets de ce modèle de soins et pour orienter le processus décisionnel clinique et la formulation de politiques en la matière. Méthodes : Le cadre d’évaluation RE-AIM a été appliqué pour nous permettre d’envisager les diverses dimensions des effets du BC Centre. Les mesures proposées, les sources de données et les stratégies de gestion des données pour cette approche à méthodes mixtes ont été identifiées. Résultats : Les cinq dimensions des effets ont été prises en considération aux niveaux personnel et organisationnel, et des indicateurs correspondants ont été proposés pour en permettre l’intégration dans l’infrastructure de données existante, en vue de faciliter la collecte des données et l’évaluation précoce du programme. Conclusion : Le cadre RE-AIM peut être appliqué à l’évaluation d’une clinique multidisciplinaire visant la douleur pelvienne chronique. Cela permettra la tenue d’une meilleure évaluation des effets de modèles novateurs de soins chez les femmes qui connaissent des douleurs pelviennes chroniques.

  16. Monitoring and analysis of the change process in curriculum mapping compared to the National Competency-based Learning Objective Catalogue for Undergraduate Medical Education (NKLM) at four medical faculties. Part I: Conducive resources and structures.

    PubMed

    Lammerding-Koeppel, Maria; Giesler, Marianne; Gornostayeva, Maryna; Narciss, Elisabeth; Wosnik, Annette; Zipfel, Stephan; Griewatz, Jan; Fritze, Olaf

    2017-01-01

    Objective: After passing of the National Competency-based Learning Objectives Catalogue in Medicine (Nationaler Kompetenzbasierter Lernzielkatalog Medizin, [NKLM, retrieved on 22.03.2016]), the German medical faculties must take inventory and develop their curricula. NKLM contents are expected to be present, but not linked well or sensibly enough in locally grown curricula. Learning and examination formats must be reviewed for appropriateness and coverage of the competences. The necessary curricular transparency is best achieved by systematic curriculum mapping, combined with effective change management. Mapping a complex existing curriculum and convincing a faculty that this will have benefits is not easy. Headed by Tübingen, the faculties of Freiburg, Heidelberg, Mannheim and Tübingen take inventory by mapping their curricula in comparison to the NKLM, using the dedicated web-based MERLIN-database. This two-part article analyses and summarises how NKLM curriculum mapping could be successful in spite of resistance at the faculties. The target is conveying the widest possible overview of beneficial framework conditions, strategies and results. Part I of the article shows the beneficial resources and structures required for implementation of curriculum mapping at the faculties. Part II describes key factors relevant for motivating faculties and teachers during the mapping process. Method: The network project was systematically planned in advance according to steps of project and change management, regularly reflected on and adjusted together in workshops and semi-annual project meetings. From the beginning of the project, a grounded-theory approach was used to systematically collect detailed information on structures, measures and developments at the faculties using various sources and methods, to continually analyse them and to draw a final conclusion (sources: surveys among the project participants with questionnaires, semi-structured group interviews and

  17. Les campagnes de dépistage du VIH, une stratégie efficace pour l’accès universel à la prévention et au traitement ? L’expérience du Burkina Faso

    PubMed Central

    Somé, J.F.; Desclaux, A.; Ky-Zerbo, O.; Lougué, M.; Kéré, S.; Obermeyer, C.; Simaga, F.

    2014-01-01

    Objectifs l’augmentation du taux de personnes qui connaissent leur statut VIH est un impératif, notamment en Afrique subsaharienne, ce qui impose d’évaluer les stratégies utilisées pour accroître la fréquentation des services de dépistage. Cet article vise à faire le bilan de la pertinence, de la faisabilité et de l’efficacité des campagnes nationales de dépistagemenées entre 2006 et 2010 au Burkina Faso. Méthodologie une analyse de toutes les données de fréquentation du conseil dépistage sur cette période a été faite, couplée à des entretiens avec les principaux acteurs intervenant dans le dépistage. Résultats les résultats montrent que les huit campagnes de dépistage organisées sur la période ont permis à 487 727 personnes de faire leur test VIH. Ce nombre représente 50 % du nombre total de personnes ayant fait leur test et contribue à hauteur de 24,6 % au dépistage des personnes séropositives identifiées au cours de cette période. Les campagnes ont touché des populations difficiles à atteindre (en particulier les jeunes), à un coût moindre. Conclusions cette stratégie est donc pertinente pour identifier les personnes VIH+. Son intérêt pour la prévention, important selon les soignants et au vu des populations jeunes qui y participent, devrait être mesuré par des études complémentaires. Les campagnes sont efficaces et coût-efficaces même dans un pays de niveau de prévalence faible. Ces résultats soulignent l’intérêt de la synergie entre les associations et les services de santé dans l’offre de services de conseil et dépistage. PMID:24681563

  18. L'intervention de Castaing dans le traitement chirurgical de l'instabilité chronique latérale de la cheville (à propos d'une série continue de 52 cas)

    PubMed Central

    Boukhris, Jalal; Mojib, Rifi; Mezghani, Sami; Jaeger, Jean Henri

    2014-01-01

    L'instabilité chronique de la cheville est l'une des évolutions possibles dans l'histoire naturelle de l'entorse aigüe de cheville. Elle représente 10% à 30% des séquelles d'entorses. Le traitement chirurgical est réservé aux patients ayant une instabilité de cheville persistante après rééducation à l'origine d'une gêne invalidante. La technique de ligamentoplastie utilisant le court fibulaire selon Castaing est la plus répondue en France. La simplicité du geste et ses bons résultats nous ont incités à poursuivre cette voie. Il s'agit d´une étude rétrospective à propos de 52 patients ayant bénéficié d'une ligamentoplastie au court fibulaire selon Castaing entre Janvier 2000 et Décembre 2010. Le recul minimum était d'un an. L’évaluation des patients reposait sur le score de Karlson et le “Ankle score” Molander et Olerud. Les patients sont satisfaits ou très satisfaits de l'intervention dans 80% des cas revus. Les résultats fonctionnels de nos patients sont comparables à ceux publiés dans la littérature. Le prélèvement du transplant du court fibulaire ne semble pas avoir de retentissement sur la stabilité de la cheville. Les patients conservent une éversion du pied satisfaisante avec une force comparable au côté opposé. L’évolution arthrosique de la cheville ne semble pas significative après cette chirurgie. Le point faible de notre étude est le nombre des patients perdus de vue, cela est lié à la jeunesse de la population opérée et au recrutement du service d'envergure nationale. PMID:25469182

  19. Aspects épidémiologiques des fractures de membres liées à l'exercice de la fonction militaire au Togo

    PubMed Central

    Akpoto, Yao Messanvi; Abalo, Anani; Gnandi-pio, Faré; Sonhaye, Lantam; Tchaou, Mazamaesso; Sama, Hamza Doles; Assenouwe, Sarakawabalo; Lamboni, Damessane; Amavi, Kossigan Adodossi; Adam, Saliou; Kpelao, Essossinam; Tengue, Kodjo; Songne-Gnamkoulamba, Badjona

    2015-01-01

    Le but de notre étude était de déterminer la fréquence des fractures de membres liées à l'exercice de la fonction militaire au sein des Forces de Défense et de Sécurité en milieu africain en vue de ressortir l'impact des différentes circonstances de survenue. Nous avons entrepris une étude rétrospective descriptive allant du 1er janvier 2004 au 31 décembre 2013. Elle a concerné les agents des forces de défense et de sécurité traités pour des fractures de membres au cours de cette période. Sept cent quatre (704) cas de fractures de membres ont été dénombrés. L’âge moyen des patients était de 30,57 ans avec des extrêmes de 19 et 55 ans. La prédominance masculine était nette (95,71%). L'Armée de Terre (51,05%) et la Gendarmerie Nationale (38,86%) étaient les plus représentées. Les hommes du rang étaient majoritaires (43,08%), suivis des sous-officiers (32,59%). La fréquence annuelle des fractures de membres en rapport avec la profession militaire était de 63 cas. Les fractures de jambe étaient les lésions les plus recensées (32,96%). Les Formations et les stages militaires ont été les circonstances de survenue les plus rencontrées (42,60%), suivies des accidents de la circulation (39,43%). La perte des journées de service liée à ces lésions était estimée à 14009 jours par an. Les fractures de jambes occupent le premier rang des fractures de membres en rapport avec l'exercice de la profession militaire. Les formations-stages militaires et les accidents de la voie publique en sont les deux grandes circonstances de survenue. PMID:27081434

  20. Monitoring and analysis of the change process in curriculum mapping compared to the National Competency-based Learning Objective Catalogue for Undergraduate Medical Education (NKLM) at four medical faculties. Part II: Key factors for motivating the faculty during the process

    PubMed Central

    Lammerding-Koeppel, Maria; Giesler, Marianne; Gornostayeva, Maryna; Narciss, Elisabeth; Wosnik, Annette; Zipfel, Stephan; Griewatz, Jan; Fritze, Olaf

    2017-01-01

    Objective: After adoption of the National Competency-based Learning Objectives Catalogue in Medicine [Nationaler Kompetenzbasierter Lernzielkatalog Medizin, NKLM], the German medical faculties are asked to test the learning obejctives recorded in it and evaluate them critically. The faculties require curricular transparency for competence-oriented transition of present curricula, which is best achieved by systematic curriculum mapping in comparison to the NKLM. Based on this inventory, curricula can be further developed target-oriented. Considerable resistance has to be expected when a complex existing curriculum is to be mapped for the first time and a faculty must be convinced of its usefulness. Headed by Tübingen, the faculties of Freiburg, Heidelberg, Mannheim and Tübingen rose to this task. This two-part article analyses and summarises how NKLM curriculum mapping was successful at the locations despite resistance. Part I presented the resources and structures that supported implementation. Part II focuses on factors that motivate individuals and groups of persons to cooperate in the faculties. Method: Both parts used the same method. In short, the joint project was systematically planned following the steps of project and change management and adjusted in the course of the process. From the beginning of the project, a Grounded-Theory approach was used to systematically collect detailed information on measures and developments at the faculties, to continually analyse them and to draw final conclusions. Results: At all sites, faculties, teachers, students and administrative staff were not per se willing to deal with the NKLM and its contents, and even less to map their present curricula. Analysis of the development reflected a number of factors that had either a negative effect on the willingness to cooperate when missing, or a positive one when present. These were: clear top-down and bottom-up management; continuous information of the faculty; user

  1. Collaborative activities and treatment outcomes in patients with HIV-associated tuberculosis in Viet Nam.

    PubMed

    Huyen, T T T; Nhung, N V; Shewade, H D; Hoa, N B; Harries, A D

    2016-03-21

    Contexte : Le programme national tuberculose (TB) au Viet Nam et à Ho Chi Minh ville (HCMC).Objectifs : Déterminer 1) au niveau national entre 2011 et 2013, la relation entre le test pour le virus de l'immunodéficience humaine (VIH), l'utilisation des interventions TB-VIH et les mauvais résultats du traitement de la TB parmi les patients TB-VIH, et 2) à HCMC en 2013, les caractéristiques des patients associées à un mauvais résultat.Schéma : Une étude écologique revoyant les données nationales agrégées et une étude de cohorte rétrospective dans HCMC.Résultats : Au niveau national, le test VIH est passé de 58% à 68% chez les patients tuberculeux et le traitement antirétroviral (ART) est passé chez les patients TB-VIH de 54% à 63% entre 2011 et 2013. Les mauvais résultats du traitement chez les patients TB-VIH ont augmenté de 24% à 27%, largement à cause des transferts (de 5% à 9%) et des décès. Les régions du Nord et des Highlands ont montré une faible utilisation des interventions TB-VIH. A HCMC, 303 (27%) patients TB-VIH sur 1110 ont eu un mauvais résultat avec un risque plus élevé observé parmi ceux qui avaient déjà eu un traitement de TB, ceux dont le diagnostic de VIH précédait l'apparition de la TB et ceux qui n'avaient jamais bénéficié du traitement par cotrimoxazole et de l'ART.Conclusion : En dépit de meilleurs taux de tests VIH et d'interventions TB-VIH, près de 26% des patients TB-VIH ont de mauvais résultats du traitement de la TB. Les facteurs de prédiction d'un risque plus élevé de mauvais résultats doivent être pris en compte si le Viet Nam souhaite mettre fin à l'épidémie de TB d'ici 2030.

  2. Evaluation de la sécurité du circuit des médicaments anticancéreux dans un hôpital régional en Tunisie

    PubMed Central

    Sahli, Jihène; El Ghardallou, Meriam; Bougmiza, Iheb; Henchiri, Besma; Limam, Manel; Mejdoub, Rim; Mtiraoui, Ali; Ajmi, Thouraya

    2016-01-01

    Introduction Parmi les événements indésirables, ceux liés au circuit des médicaments occupent une place importante et risquent de causer un préjudice grave aux patients. Dans ce contexte, nous avons mené cette étude dans l'optique de décrire et d’évaluer le circuit des médicaments anticancéreux dans un hôpital régional tunisien. Méthodes Il s'agit d'une étude évaluative du risque lié aux médicaments anticancéreux, type « visite de risque » menée sur une période de 15 jours au cours de l'année 2014 au service de cancérologie de l'hôpital régional de Gafsa (Tunisie). Cette méthode d’évaluation est inspirée de celle conduite par le projet « SECURIMED » développé par le Comité de Coordination de l'Evaluation Clinique et de la Qualité en Aquitaine (CCECQA), en France. Résultats Dans notre étude, l'observation du circuit des médicaments anticancéreux a révélé certaines insuffisances. On a noté que la répartition des missions des différents acteurs est sujette parfois à des glissements de tâches. Un manque important ainsi que une inadéquation aux normes au niveau des équipements nécessaires pour la préparation et la protection des professionnels manipulant ces médicaments ont été également décelés. Conclusion La sécurisation du circuit des médicaments devrait être une priorité inscrite dans l'ensemble des démarches nationales et partagée par tous les intervenants et ce dans l'optique d'atteindre un objectif prémium: la qualité de la prise en charge globale et la sécurité des patients. PMID:27200135

  3. Characterization of Heat Waves in the Sahel and associated mechanisms

    NASA Astrophysics Data System (ADS)

    Oueslati, Boutheina; Pohl, Benjamin; Moron, Vincent; Rome, Sandra

    2016-04-01

    Large efforts are made to investigate the heat waves (HW) in developed countries because of their devastating impacts on society, economy and environment. This interest increased after the intense event over Europe during summer 2003. However, HWs are still understudied over developing countries. This is particularly true in West Africa, and especially in the Sahel, where temperatures recurrently reach critical values, such as during the 2010 HW event. Understanding the Sahelian HWs and associated health risks constitute the main objective of ACASIS, a 4-year project funded by the French Agence Nationale de la Recherche. Our work contributes to this project and aims at characterizing the Sahelian HWs and understanding the mechanisms associated with such extreme events. There is no universal definition of a HW event, since it is highly dependent on the sector (human health, agriculture, transport...) and region of interest. In our case, a HW is defined when the heat index of the day and of the night exceeds the 90th percentile for at least 3 consecutive days (Rome et al. 2016, in preparation). This index combines temperature and relative humidity in order to determine the human-perceived equivalent temperature (definition adapted from Steadman, 1979). Intrinsic properties of Sahelian HW are analyzed from the Global Summary of the Day (GSOD) synoptic observations and ERA-interim reanalyses over 1979-2014 during boreal spring seasons (April-May-June), the warmest period of the year in the Central Sahel. ERA-interim captures well the observed interannual variability and seasonal cycle at the regional scale, as well as the 1979-2014 increasing linear trend of springtime HW occurrences in the Sahel. Reanalyses, however, overestimate the duration, spatial extent of HW, and underestimate their intensity. For both GSOD and ERA-interim, we show that, over the last three decades, Sahelian HWs tend to become more frequent, last longer, cover larger areas and reach higher

  4. Une version québécoise du Sport Concussion Assessment Tool 2 (SCAT2)—Outil d'évaluation des commotions cérébrales dans le sport 2 : Québec (SCAT2-Qc)

    PubMed Central

    Boyd, Jami; Boyer-Rémillard, Marie-Eve; Pilon-Piquette, Michael; McKinley, Patricia

    2013-01-01

    RÉSUMÉ Objectif : traduire le Sport Concussion Assessment Tool 2 (SCAT2) dans la langue française parlée au Québec et en vérifier l'acceptabilité pour la population québécoise francophone. Méthodologie : le processus de traduction de la version originale du SCAT2 a fait appel à une variante de la méthode de traduction et d'adaptation d'outils proposée par l'Organisation mondiale de la santé. Une traduction parallèle a d'abord été réalisée. Ensuite, un comité a révisé cette traduction parallèle dans le but de produire une version préliminaire du SCAT2-Qc. Puis, on a procédé à une rétrotraduction parallèle, que l'on a comparée à la version originale. La version préliminaire a été modifiée. Pour parvenir à la version finale, on a intégré les suggestions et les commentaires formulés par deux sujets sains lors de l'essai de l'outil, et lors de la comparaison du SCAT2-Qc à la version française existante par trois réviseurs du domaine de la santé. On a ensuite testé la version finale du SCAT2-Qc auprès de douze sujets sains pour en vérifier l'acceptabilité. Résultats : les douze sujets sains n'ont eu aucun problème de compréhension en utilisant le SCAT2-Qc. Conclusion : les différentes étapes de traduction ont permis de créer le SCAT2-Qc. Son contenu ayant été validé, il peut à présent être utilisé dans le milieu sportif et scientifique québécois. PMID:24396168

  5. The VIMOS VLT deep survey. The ultraviolet galaxy luminosity function and luminosity density at 3 ≤ z ≤ 4

    NASA Astrophysics Data System (ADS)

    Paltani, S.; Le Fèvre, O.; Ilbert, O.; Arnouts, S.; Bardelli, S.; Tresse, L.; Zamorani, G.; Zucca, E.; Bottini, D.; Garilli, B.; Le Brun, V.; Maccagni, D.; Picat, J.-P.; Scaramella, R.; Scodeggio, M.; Vettolani, G.; Zanichelli, A.; Adami, C.; Bolzonella, M.; Cappi, A.; Charlot, S.; Ciliegi, P.; Contini, T.; Foucaud, S.; Franzetti, P.; Gavignaud, I.; Guzzo, L.; Iovino, A.; McCracken, H. J.; Marano, B.; Marinoni, C.; Mazure, A.; Meneux, B.; Merighi, R.; Pellò, R.; Pollo, A.; Pozzetti, L.; Radovich, M.; Bondi, M.; Bongiorno, A.; Brinchmann, J.; Cucciati, O.; de la Torre, S.; Lamareille, F.; Mellier, Y.; Merluzzi, P.; Temporin, S.; Vergani, D.; Walcher, C. J.

    2007-03-01

    -forming galaxies in the history of star formation. Based on observations collected at the European Southern Observatory Very Large Telescope, Paranal, Chile, program 070.A-9007(A). Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  6. The VIMOS VLT deep survey. The K-band follow-up in the 0226-04 field

    NASA Astrophysics Data System (ADS)

    Temporin, S.; Iovino, A.; Bolzonella, M.; McCracken, H. J.; Scodeggio, M.; Garilli, B.; Bottini, D.; Le Brun, V.; Le Fèvre, O.; Maccagni, D.; Picat, J. P.; Scaramella, R.; Tresse, L.; Vettolani, G.; Zanichelli, A.; Adami, C.; Arnouts, S.; Bardelli, S.; Cappi, A.; Charlot, S.; Ciliegi, P.; Contini, T.; Cucciati, O.; Foucaud, S.; Franzetti, P.; Gavignaud, I.; Guzzo, L.; Ilbert, O.; Marano, B.; Marinoni, C.; Mazure, A.; Meneux, B.; Merighi, R.; Paltani, S.; Pellò, R.; Pollo, A.; Pozzetti, L.; Radovich, M.; Vergani, D.; Zamorani, G.; Zucca, E.; Bondi, M.; Bongiorno, A.; Brinchmann, J.; de la Torre, S.; Lamareille, F.; Mellier, Y.; Walcher, C. J.

    2008-04-01

    We present a new K_s-band survey that represents a significant extension to the previous wide-field K_s-band imaging survey within the 0226-04 field of the VIMOS-VLT deep survey (VVDS). The new data add ~458 arcmin2 to the previous imaging program, thus allowing us to cover a total contiguous area of ~600 arcmin2 within this field. Sources were identified both directly on the final K-band mosaic image and on the corresponding, deep χ^2-g'r'i' image from the CFHT Legacy Survey in order to reduce contamination, while ensuring compilation of a truly K-selected catalogue down to the completeness limit of the K_s-band. The newly determined K_s-band magnitudes are used in combination with the ancillary multiwavelength data for determining accurate photometric redshifts. The final catalogue totals ~52 000 sources, out of which ~4400 have a spectroscopic redshift from the VVDS first epoch survey. The catalogue is 90% complete down to KVega = 20.5 mag. We present K_s-band galaxy counts and angular correlation function measurements down to this magnitude limit. Our results are in good agreement with previously published work. We show that using K magnitudes to determine photometric redshifts significantly lowers the incidence of catastrophic errors. The data presented in this paper are publicly available through the CENCOS database. Based on observations collected at the European Southern Observatory New Technology Telescope, La Silla, Chile, programme 075.A-0752(A), on data obtained with the European Southern Observatory Very Large Telescope, Paranal, Chile, programme 070.A-9007(A), and on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council (NRC) of Canada, the Institut National des Science de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. This work is based in part on data products

  7. A Statistical Study of Multiply Imaged Systems in the Lensing Cluster Abell 68

    NASA Astrophysics Data System (ADS)

    Richard, Johan; Kneib, Jean-Paul; Jullo, Eric; Covone, Giovanni; Limousin, Marceau; Ellis, Richard; Stark, Daniel; Bundy, Kevin; Czoske, Oliver; Ebeling, Harald; Soucail, Geneviève

    2007-06-01

    (program 8249) obtained at the Space Telescope Science Institute, which is operated by AURA under NASA contract NAS5-26555, and the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  8. Photometric redshifts as a tool for studying the Coma cluster galaxy populations

    NASA Astrophysics Data System (ADS)

    Adami, C.; Ilbert, O.; Pelló, R.; Cuillandre, J. C.; Durret, F.; Mazure, A.; Picat, J. P.; Ulmer, M. P.

    2008-12-01

    Aims: We apply photometric redshift techniques to an investigation of the Coma cluster galaxy luminosity function (GLF) at faint magnitudes, in particular in the u* band where basically no studies are presently available at these magnitudes. Methods: Cluster members were selected based on probability distribution function from photometric redshift calculations applied to deep u^*, B, V, R, I images covering a region of almost 1 deg2 (completeness limit R ~ 24). In the area covered only by the u* image, the GLF was also derived after a statistical background subtraction. Results: Global and local GLFs in the B, V, R, and I bands obtained with photometric redshift selection are consistent with our previous results based on a statistical background subtraction. The GLF in the u* band shows an increase in the faint end slope towards the outer regions of the cluster. The analysis of the multicolor type spatial distribution reveals that late type galaxies are distributed in clumps in the cluster outskirts, where X-ray substructures are also detected and where the GLF in the u* band is steeper. Conclusions: We can reproduce the GLFs computed with classical statistical subtraction methods by applying a photometric redshift technique. The u* GLF slope is steeper in the cluster outskirts, varying from α ~ -1 in the cluster center to α ~ -2 in the cluster periphery. The concentrations of faint late type galaxies in the cluster outskirts could explain these very steep slopes, assuming a short burst of star formation in these galaxies when entering the cluster. Based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. This work is also partly based on data products produced at

  9. The SECOQC quantum key distribution network in Vienna

    NASA Astrophysics Data System (ADS)

    Peev, M.; Pacher, C.; Alléaume, R.; Barreiro, C.; Bouda, J.; Boxleitner, W.; Debuisschert, T.; Diamanti, E.; Dianati, M.; Dynes, J. F.; Fasel, S.; Fossier, S.; Fürst, M.; Gautier, J.-D.; Gay, O.; Gisin, N.; Grangier, P.; Happe, A.; Hasani, Y.; Hentschel, M.; Hübel, H.; Humer, G.; Länger, T.; Legré, M.; Lieger, R.; Lodewyck, J.; Lorünser, T.; Lütkenhaus, N.; Marhold, A.; Matyus, T.; Maurhart, O.; Monat, L.; Nauerth, S.; Page, J.-B.; Poppe, A.; Querasser, E.; Ribordy, G.; Robyr, S.; Salvail, L.; Sharpe, A. W.; Shields, A. J.; Stucki, D.; Suda, M.; Tamas, C.; Themel, T.; Thew, R. T.; Thoma, Y.; Treiber, A.; Trinkler, P.; Tualle-Brouri, R.; Vannel, F.; Walenta, N.; Weier, H.; Weinfurter, H.; Wimberger, I.; Yuan, Z. L.; Zbinden, H.; Zeilinger, A.

    2009-07-01

    In this paper, we present the quantum key distribution (QKD) network designed and implemented by the European project SEcure COmmunication based on Quantum Cryptography (SECOQC) (2004-2008), unifying the efforts of 41 research and industrial organizations. The paper summarizes the SECOQC approach to QKD networks with a focus on the trusted repeater paradigm. It discusses the architecture and functionality of the SECOQC trusted repeater prototype, which has been put into operation in Vienna in 2008 and publicly demonstrated in the framework of a SECOQC QKD conference held from October 8 to 10, 2008. The demonstration involved one-time pad encrypted telephone communication, a secure (AES encryption protected) video-conference with all deployed nodes and a number of rerouting experiments, highlighting basic mechanisms of the SECOQC network functionality. The paper gives an overview of the eight point-to-point network links in the prototype and their underlying technology: three plug and play systems by id Quantique, a one way weak pulse system from Toshiba Research in the UK, a coherent one-way system by GAP Optique with the participation of id Quantique and the AIT Austrian Institute of Technology (formerly ARCAustrian Research Centers GmbH—ARC is now operating under the new name AIT Austrian Institute of Technology GmbH following a restructuring initiative.), an entangled photons system by the University of Vienna and the AIT, a continuous-variables system by Centre National de la Recherche Scientifique (CNRS) and THALES Research and Technology with the participation of Université Libre de Bruxelles, and a free space link by the Ludwig Maximillians University in Munich connecting two nodes situated in adjacent buildings (line of sight 80 m). The average link length is between 20 and 30 km, the longest link being 83 km. The paper presents the architecture and functionality of the principal networking agent—the SECOQC node module, which enables the authentic

  10. Laboratory experiments for Titan's ionosphere : the photoionisation of hydrocarbon radicals CxHy.

    NASA Astrophysics Data System (ADS)

    Alcaraz, C.; Fischer, I.; Schussler, T.; Deyerl, H.-J.; Roth, W.; Elhanine, M.; Gerber, T.

    .; Gerber, T.; Alcaraz, C.; Fischer, I. Phys. Chem. Chem. 1 Phys. 2005, 7, 819. (3) http://www.clups.u-psud.fr/ (4) http://www.synchrotron-soleil.fr/francais/vie-scientifique/experiences/desirs/index.htm 2

  11. Designing a new post-hole seismological station on Antarctica inlandsis (Concordia station)

    NASA Astrophysics Data System (ADS)

    Bès de Berc, M.; Maggi, A.; Leveque, J. J.; Thore, J. Y.

    2015-12-01

    of ice.The drilling will be carried out by the French drilling facility C2FN (Centre de Carottage et de Forage National) of the CNRS (Centre National de la Recherche Scientifique), and the is planned for the 2018-2019 summer season.

  12. Stellar Evolution in NGC 6791: Mass Loss on the Red Giant Branch and the Formation of Low-Mass White Dwarfs

    NASA Astrophysics Data System (ADS)

    Kalirai, Jasonjot S.; Bergeron, P.; Hansen, Brad M. S.; Kelson, Daniel D.; Reitzel, David B.; Rich, R. Michael; Richer, Harvey B.

    2007-12-01

    Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  13. Toward Understanding the B[e] Phenomenon: V. Nature and Spectral Variations of the MWC 728 Binary System.

    NASA Astrophysics Data System (ADS)

    Miroshnichenko, A. S.; Zharikov, S. V.; Danford, S.; Manset, N.; Korčáková, D.; Kříček, R.; Šlechta, M.; Omarov, Ch. T.; Kusakin, A. V.; Kuratov, K. S.; Grankin, K. N.

    2015-08-01

    We report the results of a long-term spectroscopic monitoring of the FS CMa type object MWC 728. We found that it is a binary system with a B5 ve ({T}{eff} = 14,000 ± 1000 K) primary and a G8 iii type ({T}{eff} ˜ 5000 K) secondary. Absorption line positions of the secondary vary, with a semi-amplitude of ˜20 km s-1 and a period of 27.5 days. The system’s mass function is 2.3 × 10-2 {M}⊙ , and its orbital plane is ˜13°-15° tilted from the plane of the sky. The primary’s v{sin}i˜ 110 km s-1, combined with this tilt, implies that it rotates at a nearly breakup velocity. We detected strong variations of the Balmer and He i emission-line profiles on timescales from days to years. This points to a variable stellar wind of the primary in addition to the presence of a circum-primary gaseous disk. The strength of the absorption-line spectrum, along with the optical and near infrared (IR) continuum, suggest that the primary contributes ˜60% of the V-band flux, the disk contributes ˜30%, and the secondary contributes ˜10%. The system parameters, along with the interstellar extinction, suggest a distance of ˜1 kpc, that the secondary does not fill its Roche lobe, and that the companions’ mass ratio is q ˜ 0.5. Overall, the observed spectral variability and the presence of a strong IR-excess are in agreement with a model of a close binary system that has undergone a non-conservative mass-transfer. of the Centre National de la Recherche Scientifique de France, and the University of Hawaii as well as on observations obtained at the 2.7 m Harlan J. Smith telescope of the McDonald Observatory (Texas, USA), 2.1 m of the Observatorio Astronomico Nacional San Pedro Martir (Baja California, Mexico), 2 m telescope of the Ondřejov Observatory, Czech Republic, and 0.81 m telescope of the Three College Observatory, North Carolina, USA.

  14. A comprehensive analysis of the magnetic standard star HD 94660: Host of a massive compact companion?

    NASA Astrophysics Data System (ADS)

    Bailey, J. D.; Grunhut, J.; Landstreet, J. D.

    2015-03-01

    ) telescopes under the ESO programme 093.D-0367(A) and programmes 076.D-0169(A), 088.D-0066(A), 087.D-0771(A), 084.D-0338(A), 083.D-1000(A) and 60.A-9036(A), obtained from the ESO/ST-ECF Science Archive Facility. It is also based in part on observations carried out at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Science de l'Univers of the Centre National de la Recherche Scientifique of France and the University of Hawaii.

  15. Teaching About The Nexus of Energy, Water and Climate Through Traditional Games

    NASA Astrophysics Data System (ADS)

    Hall, M. K.; Mayhew, M. A.; Kaminsky, A.

    2011-12-01

    Getting to a sustainable energy economy, while conserving water resources and mitigating climate change, will involve myriad choices. Thus, it is important that the American public have an improved science-based understanding to form a strong basis for decision-making and to understand the trade-offs. To address this need, we are developing compelling, resource management style games that convey the intimate inter-relationships among energy demand, water consumption, and climate change and the importance of these inter-relationships to society. We have developed a card game with the help of professional game developer and an advisory group consisting of high school students and scientists involved with different aspects of energy-climate-water research as well as experts from the energy utilities and regulatory sectors. We have developed the card game based on real world data on energy production and consumption, regional climate information, and knowledge of emerging technologies that would mitigate the demand for energy, consumption of water with energy production, or climate change. The game is being played within the setting of our Cafe Scientifique program, now in its fifth year of serving high school age teens. One of the important aspects of the game is to find the right balance of energy output for various sources, water use by these sources, and amount of "pollution" generated (CO2 impacting climate, but also other kinds, such a radioactive waste and ground water contamination). Each player acts as "governor" of a specific region of the country, and no region has an a priori advantage. At the same time, it is important that the energy-water-pollution values we use correspond as closely as possible to real-world values. Data gathered from a combination of focus groups, surveys, and observations strongly suggest that this game, grounded in real life problems, stimulates authentic, meaningful learning. There is also some evidence that if games, such as this

  16. Testing the theory of colliding winds: the periastron passage of 9 Sagittarii. I. X-ray and optical spectroscopy

    NASA Astrophysics Data System (ADS)

    Rauw, G.; Blomme, R.; Nazé, Y.; Spano, M.; Mahy, L.; Gosset, E.; Volpi, D.; van Winckel, H.; Raskin, G.; Waelkens, C.

    2016-05-01

    Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias. Based on observations obtained with the HERMES spectrograph, which is supported by the Fund for Scientific Research of Flanders (FWO), Belgium, the Research Council of K.U. Leuven, Belgium, the Fonds National de la Recherche Scientifique (F.R.S.-FNRS), Belgium, the Royal Observatory of Belgium, the Observatoire de Genève, Switzerland and the Thüringer Landessternwarte Tautenburg, Germany.

  17. Investigations of two-phase flame propagation under microgravity conditions

    NASA Astrophysics Data System (ADS)

    Gokalp, Iskender

    2016-07-01

    Investigations of two-phase flame propagation under microgravity conditions R. Thimothée, C. Chauveau, F. Halter, I Gökalp Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE), CNRS, 1C Avenue de la Recherche Scientifique, 45071 Orléans Cedex 2, France This paper presents and discusses recent results on two-phase flame propagation experiments we carried out with mono-sized ethanol droplet aerosols under microgravity conditions. Fundamental studies on the flame propagation in fuel droplet clouds or sprays are essential for a better understanding of the combustion processes in many practical applications including internal combustion engines for cars, modern aircraft and liquid rocket engines. Compared to homogeneous gas phase combustion, the presence of a liquid phase considerably complicates the physico-chemical processes that make up combustion phenomena by coupling liquid atomization, droplet vaporization, mixing and heterogeneous combustion processes giving rise to various combustion regimes where ignition problems and flame instabilities become crucial to understand and control. Almost all applications of spray combustion occur under high pressure conditions. When a high pressure two-phase flame propagation is investigated under normal gravity conditions, sedimentation effects and strong buoyancy flows complicate the picture by inducing additional phenomena and obscuring the proper effect of the presence of the liquid droplets on flame propagation compared to gas phase flame propagation. Conducting such experiments under reduced gravity conditions is therefore helpful for the fundamental understanding of two-phase combustion. We are considering spherically propagating two-phase flames where the fuel aerosol is generated from a gaseous air-fuel mixture using the condensation technique of expansion cooling, based on the Wilson cloud chamber principle. This technique is widely recognized to create well-defined mono-size droplets

  18. La physique nucléaire en astrophysique

    NASA Astrophysics Data System (ADS)

    Arnould, M.; Samyn, M.

    é nucléaire. Bien que des progrès considérables ont été réalisés dans cette exploration, nous mettons en évidence que bien du travail reste à faire et qu'une meilleure compréhension mutuelle entre physiciens nucléaires et astrophysiciens ne pourrait manquer d'être la source de nouvelles et exaltantes aventures scientifiques.

  19. Interior rotation of a sample of γ Doradus stars from ensemble modelling of their gravity-mode period spacings

    NASA Astrophysics Data System (ADS)

    Van Reeth, T.; Tkachenko, A.; Aerts, C.

    2016-10-01

    Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias, and supported by the Fund for Scientific Research of Flanders (FWO), Belgium, the Research Council of KU Leuven, Belgium, the Fonds National de la Recherche Scientifique (F.R.S.-FNRS), Belgium, the Royal Observatory of Belgium, the Observatoire de Genève, Switzerland, and the Thüringer Landessternwarte Tautenburg, Germany.

  20. Nonequilibrium dynamics in chemical systems A brief account

    NASA Astrophysics Data System (ADS)

    Nicolis, G.; Baras, F.

    1985-12-01

    During the period of September 3 to 7, 1984 a symposium on “Nonequilibrium Dynamics in Chemical Systems” was organized by the Centre de Recherche Paul Pascal in Bordeaux, France. It was supported, primarily, by the French Centre National de la Recherche Scientifique and attended by about 90 participants from Australia, Belgium, Canada, Denmark, France, Germany, Hungary, Israël, Italy, Japan, The Netherlands, Poland, Tchekoslovakia, Spain, United Kingdom, United States and Zimbabwe. A list of topics and speakers is found in the table below. Two highly successful conferences centered on nonlinear phenomena in chemical systems far from equilibrium had already been organized by the Bordeaux group in the past. The first of them [1], held in September 1978, was dominated by the theme that nonequilibrium can act as a source of order. Sustained oscillations and bistability were the two principal phenomena studied from this point of view. Thanks to the systematic utilization of the continuous stirred tank reactor (CSTR) the study of open systems could finally be realized. Reliable state diagrams were thus produced, notably by the Bordeaux group, in which one could identify the transition points to new states. The Belousov-Zhabotinskii (BZ) reaction and its variants were the main vehicle on which these new ideas could be illustrated. The second Bordeaux conference [2], held in September 1981, was largely dominated by the major progress that had just marked two vital areas of this field: the discovery of new classes of chemical oscillators; and the invasion of chaotic dynamics in chemistry. These themes also dominated the first Gordon Conference on Chemical Oscillations held in New Hampshire in July 1982. In contrast to its two predecessors, the third Bordeaux conference held in September 1984 was not dominated by a single central theme. New questions were raised in situations in which until very recently things were considered to be perfectly clear. Simple,