Sample records for bidirectional current flow

  1. Indirect current control with separate IZ drop compensation for voltage source converters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kanetkar, V.R.; Dawande, M.S.; Dubey, G.K.

    1995-12-31

    Indirect Current Control (ICC) of boost type Voltage Source Converters (VSCs) using separate compensation of line IZ voltage drop is presented. A separate bi-directional VSC is used to produce the compensation voltage. This simplifies the ICC regulator scheme as the power flow is controlled through single modulation index. Experimental verification is provided for bi-directional control of the power flow.

  2. Rapid response to coastal upwelling in a semienclosed bay

    NASA Astrophysics Data System (ADS)

    Gilcoto, Miguel; Largier, John L.; Barton, Eric D.; Piedracoba, Silvia; Torres, Ricardo; Graña, Rocío.; Alonso-Pérez, Fernando; Villacieros-Robineau, Nicolás.; de la Granda, Francisco

    2017-03-01

    Bays/estuaries forced by local wind show bidirectional exchange flow. When forced by remote wind, they exhibit unidirectional flow adjustment to coastal sea level. Acoustic Doppler Current Profiler observations over 1 year show that the Ria de Vigo (Iberian Upwelling) responds to coastal wind events with bidirectional exchange flow. The duration of the upwelling and downwelling events, estimated from the current variability, was 3.3 days and 2.6 days, respectively. Vectorial correlations reveal a rapid response to upwelling/downwelling, in which currents lag local wind by <6 h and remote wind by <14 h, less than the Ekman spinup (17.8 h). This rapidity arises from the ria's narrowness (nonrotational local response), equatorward orientation (additive remote and local wind responses), depth greater than the Ekman depth (penetration of shelf circulation into the interior), and vertical stratification (shear reinforcing shelf circulation). Similar rapid responses are expected in other narrow bays where local and remote winds act together and stratification enhances bidirectional flow.

  3. Conceptual Design of a 100kW Energy Integrated Type Bi-Directional Tidal Current Turbine

    NASA Astrophysics Data System (ADS)

    Kim, Ki Pyoung; Ahmed, M. Rafiuddin; Lee, Young Ho

    2010-06-01

    The development of a tidal current turbine that can extract maximum energy from the tidal current will be extremely beneficial for supplying continuous electric power. The present paper presents a conceptual design of a 100kW energy integrated type tidal current turbine for tidal power generation. The instantaneous power density of a flowing fluid incident on an underwater turbine is proportional to the cubic power of current velocity which is approximately 2.5m/s. A cross-flow turbine, provided with a nozzle and a diffuser, is designed and analyzed. The potential advantages of ducted and diffuser-augmented turbines were taken into consideration in order to achieve higher output at a relatively low speed. This study looks at a cross-flow turbine system which is placed in an augmentation channel to generate electricity bi-directionally. The compatibility of this turbine system is verified using a commercial CFD code, ANSYSCFX. This paper presents the results of the numerical analysis in terms of pressure, streaklines, velocity vectors and performance curves for energy integrated type bi-directional tidal current turbine (BDT) with augmentation.

  4. Inverting Quasi-Resonant Switched-Capacitor Bidirectional Converter and Its Application to Battery Equalization

    NASA Astrophysics Data System (ADS)

    Lee, Yuang-Shung; Chiu, Yin-Yuan; Cheng, Ming-Wang; Ko, Yi-Pin; Hsiao, Sung-Hsin

    The proposed quasi-resonant (QR) zero current switching (ZCS) switched-capacitor (SC) converter is a new type of bidirectional power flow control conversion scheme. The proposed converter is able to provide voltage conversion ratios from -3/-{1 \\over 3} (triple-mode/trisection-mode) to -n/-{1 \\over n} (-n-mode/-{1 \\over n}-mode) by adding a different number of switched-capacitors and power MOSFET switches with a small series connected resonant inductor for forward and reverse power flow control schemes. It possesses the advantages of low switching losses and current stress in this QR ZCS SC converter. The principle of operation, theoretical analysis of the proposed triple-mode/trisection-mode bidirectional power conversion scheme is described in detail with circuit model analysis. Simulation and experimental studies are carried out to verify the performance of the proposed inverting type ZCS SC QR bidirectional converter. The proposed converters can be applied to battery equalization for battery management system (BMS).

  5. Bidirectional Pressure-Regulator System

    NASA Technical Reports Server (NTRS)

    Burke, Kenneth; Miller, John R.

    2008-01-01

    A bidirectional pressure-regulator system has been devised for use in a regenerative fuel cell system. The bidirectional pressure-regulator acts as a back-pressure regulator as gas flows through the bidirectional pressure-regulator in one direction. Later, the flow of gas goes through the regulator in the opposite direction and the bidirectional pressure-regulator operates as a pressure- reducing pressure regulator. In the regenerative fuel cell system, there are two such bidirectional regulators, one for the hydrogen gas and another for the oxygen gas. The flow of gases goes from the regenerative fuel cell system to the gas storage tanks when energy is being stored, and reverses direction, flowing from the storage tanks to the regenerative fuel cell system when the stored energy is being withdrawn from the regenerative fuel cell system. Having a single bidirectional regulator replaces two unidirectional regulators, plumbing, and multiple valves needed to reverse the flow direction. The term "bidirectional" refers to both the bidirectional nature of the gas flows and capability of each pressure regulator to control the pressure on either its upstream or downstream side, regardless of the direction of flow.

  6. The influence of following on bidirectional flow through a doorway

    NASA Astrophysics Data System (ADS)

    Graves, Amy; Diamond, Rachel; Saakashvili, Eduard

    Pedestrian dynamics is a subset of the study of self-propelled particles. We simulate two species of pedestrians undergoing bidirectional flow through a narrow doorway. Using the Helbing-Monlár-Farkas-Vicsek Social Force Model, our pedestrians are soft discs that experience psychosocial and physical contact forces. We vary the ``following'' parameter which determines the degree to which a pedestrian matches its direction of movement to the average of nearby, same-species pedestrians. Current density, efficiency and statistics of bursts and lags are calculated. These indicate that choosing different following parameters for each species affects the efficacy of transport - greater following being associated with lower efficacy. The information entropy associated with velocity and the long time tails of the complementary CDF of lag times are additional indicators of the dynamical consequences of following during bidirectional flow. Acknowledgement is made to the donors of the ACS Petrolium Research Fund, and the Vandervelde-Cheung Fund of Swarthmore College.

  7. Measuring bi-directional current through a field-effect transistor by virtue of drain-to-source voltage measurement

    DOEpatents

    Turner, Steven Richard

    2006-12-26

    A method and apparatus for measuring current, and particularly bi-directional current, in a field-effect transistor (FET) using drain-to-source voltage measurements. The drain-to-source voltage of the FET is measured and amplified. This signal is then compensated for variations in the temperature of the FET, which affects the impedance of the FET when it is switched on. The output is a signal representative of the direction of the flow of current through the field-effect transistor and the level of the current through the field-effect transistor. Preferably, the measurement only occurs when the FET is switched on.

  8. Comparison of control structures for a bidirectional high-frequency dc-dc converter

    NASA Astrophysics Data System (ADS)

    Himmelstoss, Felix A.; Kolar, Johann W.; Zach, Franz C.

    1989-08-01

    A system for dc-dc power conversion based on a buck-boost converter topology is presented. It makes power flow in both directions possible. The possibility of bidirectional power flow is useful for certain applications, such as uninterruptable power supplies. Starting from a structural diagram the transfer function of the system is derived. The controller for the converter is then designed. It is made up of a simple voltage controller, a voltage controller with an inner loop current controller (cascade control) and with two kinds of state space control. The transfer functions of the different system parts are derived and dimensioning guidelines for the controller sections are presented. The closed loop behavior of the bidirectional converter for the different control structures is analyzed based on simulation using duty cycle averaging. Bodediagrams and step responses are shown.

  9. Solid-state circuit breaker with current-limiting characteristic using a superconducting coil

    DOEpatents

    Boenig, H.J.

    1982-08-16

    A thyristor bridge interposes an ac source and a load. A series connected DC source and superconducting coil within the bridge biases the thyristors thereof so as to permit bidirectional ac current flow therethrough under normal operating conditions. Upon a fault condition a control circuit triggers the thyristors so as to reduce ac current flow therethrough to zero in less than two eyeles and to open the bridge thereafter. Upon a temporary overload condition the control circuit triggers the thyristors so as to limit ac current flow therethrough to an acceptable level.

  10. Solid-state circuit breaker with current limiting characteristic using a superconducting coil

    DOEpatents

    Boenig, Heinrich J.

    1984-01-01

    A thyristor bridge interposes an ac source and a load. A series connected DC source and superconducting coil within the bridge biases the thyristors thereof so as to permit bidirectional ac current flow therethrough under normal operating conditions. Upon a fault condition a control circuit triggers the thyristors so as to reduce ac current flow therethrough to zero in less than two cycles and to open the bridge thereafter. Upon a temporary overload condition the control circuit triggers the thyristors so as to limit ac current flow therethrough to an acceptable level.

  11. Battery charging and discharging research based on the interactive technology of smart grid and electric vehicle

    NASA Astrophysics Data System (ADS)

    Zhang, Mingyang

    2018-06-01

    To further study the bidirectional flow problem of V2G (Vehicle to Grid) charge and discharge motor, the mathematical model of AC/DC converter and bi-directional DC/DC converter was established. Then, lithium battery was chosen as the battery of electric vehicle and its mathematical model was established. In order to improve the service life of lithium battery, bidirectional DC/DC converter adopted constant current and constant voltage control strategy. In the initial stage of charging, constant current charging was adopted with current single closed loop control. After reaching a certain value, voltage was switched to constant voltage charging controlled by voltage and current. Subsequently, the V2G system simulation model was built in MATLAB/Simulink. The simulation results verified the correctness of the control strategy and showed that when charging, constant current and constant voltage charging was achieved, the grid side voltage and current were in the same phase, and the power factor was about 1. When discharging, the constant current discharge was applied, and the grid voltage and current phase difference was r. To sum up, the simulation results are correct and helpful.

  12. Density currents in the Chicago River: Characterization, effects on water quality, and potential sources

    USGS Publications Warehouse

    Jackson, P. Ryan; Garcia, Carlos M.; Oberg, Kevin A.; Johnson, Kevin K.; Garcia, Marcelo H.

    2008-01-01

    Bidirectional flows in a river system can occur under stratified flow conditions and in addition to creating significant errors in discharge estimates, the upstream propagating currents are capable of transporting contaminants and affecting water quality. Detailed field observations of bidirectional flows were made in the Chicago River in Chicago, Illinois in the winter of 2005-06. Using multiple acoustic Doppler current profilers simultaneously with a water-quality profiler, the formation of upstream propagating density currents within the Chicago River both as an underflow and an overflow was observed on three occasions. Density differences driving the flow primarily arise from salinity differences between intersecting branches of the Chicago River, whereas water temperature is secondary in the creation of these currents. Deicing salts appear to be the primary source of salinity in the North Branch of the Chicago River, entering the waterway through direct runoff and effluent from a wastewater-treatment plant in a large metropolitan area primarily served by combined sewers. Water-quality assessments of the Chicago River may underestimate (or overestimate) the impairment of the river because standard water-quality monitoring practices do not account for density-driven underflows (or overflows). Chloride concentrations near the riverbed can significantly exceed concentrations at the river surface during underflows indicating that full-depth parameter profiles are necessary for accurate water-quality assessments in urban environments where application of deicing salt is common.

  13. CFD Approach To Investigate The Flow Characteristics In Bi-Directional Ventilated Disc Brake

    NASA Astrophysics Data System (ADS)

    Munisamy, Kannan M.; Yusoff, Mohd. Zamri; Shuaib, Norshah Hafeez; Thangaraju, Savithry K.

    2010-06-01

    This paper presents experimental and Computational Fluids Dynamics (CFD) investigations of the flow in ventilated brake discs. Development of an experiment rig with basic measuring devices are detailed out and following a validation study, the possible improvement in the brake cooling can be further analyzed using CFD analysis. The mass flow rate is determined from basic flow measurement technique following that the conventional bi-directional passenger car is simulated using commercial CFD software FLUENT™. The CFD simulation is used to investigate the flow characteristics in between blade flow of the bi-directional ventilated disc brake.

  14. Low energy proton bidirectional anisotropies and their relation to transient interplanetary magnetic structures: ISEE-3 observations

    NASA Technical Reports Server (NTRS)

    Marsden, R. G.; Sanderson, T. R.; Wenzel, K. P.; Smith, E. J.

    1985-01-01

    It is known that the interplanetary medium in the period approaching solar maximum is characterized by an enhancement in the occurrence of transient solar wind streams and shocks and that such systems are often associated with looplike magnetic structures or clouds. There is observational evidence that bidirectional, field aligned flows of low energy particles could be a signature of such looplike structures, although detailed models for the magnetic field configuration and injection mechanisms do not exist at the current time. Preliminary results of a survey of low energy proton bidirectional anisotropies measured on ISEE-3 in the interplanetary medium between August 1978 and May 1982, together with magnetic field data from the same spacecraft are presented.

  15. Spectroscopic Measurement of Ion Flow During Merging Start-up of Field-Reversed Configuration

    NASA Astrophysics Data System (ADS)

    Oka, Hirotaka; Inomoto, Michiaki; Tanabe, Hiroshi; Annoura, Masanobu; Ono, Yasushi; Nemoto, Koshichi

    2012-10-01

    The counter-helicity merging method [1] of field-reversed configuration (FRC) formation involves generation of bidirectional toroidal flow, known as a ``sling-shot.'' In two fluids regime, reconnection process is strongly affected by the Hall effect [2]. In this study, we have investigated the behavior of toroidal bidirectional flow generated by the counter-helicity merging in two-fluids regime. We use 2D Ion Doppler Spectroscopy to mesure toroidal ion flow during merging start-up of FRC from Ar gas. We defined two cases: one case with a radially pushed-in X line (case I) and the other case with a radially pushed-out X line(case O). The flow during the plasma merging shows radial asymmetry, as expected from the magnetic measurement, but finally relaxes to a unidirectional flow in plasma current direction in both cases. We observed larger toroidal flow in the plasma current direction in case I after FRC is formed, though the FRC in case O has larger magnetic flux. These results suggest that more ions are lost during merging start-up in case I. This selective ion loss might account for stability and confinement of FRCs probably maintained by high energy ions.[4pt] [1] Y. Ono, et al., Nucl. Fusion 39, pp. 2001-2008 (1999).[0pt] [2] M. Inomoto, et al., Phys. Rev. Lett., 97, 135002, (2006)

  16. Bi-directional flow induced by an AC electroosmotic micropump with DC voltage bias.

    PubMed

    Islam, Nazmul; Reyna, Jairo

    2012-04-01

    This paper discusses the principle of biased alternating current electroosmosis (ACEO) and its application to move the bulk fluid in a microchannel, as an alternative to mechanical pumping methods. Previous EO-driven flow research has looked at the effect of electrode asymmetry and transverse traveling wave forms on the performance of electroosmotic pumps. This paper presents an analysis that was conducted to assess the effect of combining an AC signal with a DC (direct current) bias when generating the electric field needed to impart electroosmosis (EO) within a microchannel. The results presented here are numerical and experimental. The numerical results were generated through simulations performed using COMSOL 3.5a. Currently available theoretical models for EO flows were embedded in the software and solved numerically to evaluate the effects of channel geometry, frequency of excitation, electrode array geometry, and AC signal with a DC bias on the flow imparted on an electrically conducting fluid. Simulations of the ACEO flow driven by a constant magnitude of AC voltage over symmetric electrodes did not indicate relevant net flows. However, superimposing a DC signal over the AC signal on the same symmetric electrode array leads to a noticeable net forward flow. Moreover, changing the polarity of electrical signal creates a bi-directional flow on symmetrical electrode array. Experimental flow measurements were performed on several electrode array configurations. The mismatch between the numerical and experimental results revealed the limitations of the currently available models for the biased EO. However, they confirm that using a symmetric electrode array excited by an AC signal with a DC bias leads to a significant improvement in flow rates in comparison to the flow rates obtained in an asymmetric electrode array configuration excited just with an AC signal. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Design of Bi-Directional Hydrofoils for Tidal Current Turbines

    NASA Astrophysics Data System (ADS)

    Nedyalkov, Ivaylo; Wosnik, Martin

    2015-11-01

    Tidal Current Turbines operate in flows which reverse direction. Bi-directional hydrofoils have rotational symmetry and allow such turbines to operate without the need for pitch or yaw control, decreasing the initial and maintenance costs. A numerical test-bed was developed to automate the simulations of hydrofoils in OpenFOAM and was utilized to simulate the flow over eleven classes of hydrofoils comprising a total of 700 foil shapes at different angles of attack. For promising candidate foil shapes physical models of 75 mm chord and 150 mm span were fabricated and tested in the University of New Hampshire High-Speed Cavitation Tunnel (HiCaT). The experimental results were compared to the simulations for model validation. The numerical test-bed successfully generated simulations for a wide range of foil shapes, although, as expected, the k - ω - SST turbulence model employed here was not adequate for some of the foils and for large angles of attack at which separation occurred. An optimization algorithm is currently being coupled with the numerical test-bed and additional turbulence models will be implemented in the future.

  18. DEVELOPMENT AND DEMONSTRATION OF A BIDIRECTIONAL ADVECTIVE FLUX METER FOR SEDIMENT-WATER INTERFACE

    EPA Science Inventory

    A bidirectional advective flux meter for measuring water transport across the sediment-water interface has been successfully developed and field tested. The flow sensor employs a heat-pulse technique combined with a flow collection funnel for the flow measurement. Because the dir...

  19. Characterizing a December 2005 density current event in the Chicago River, Chicago, Illinois

    USGS Publications Warehouse

    Garcia, C.M.; Jackson, P.R.; Oberg, K.A.; Johnson, K.K.; Garcia, M.H.

    2007-01-01

    During the winter months, the Chicago River in Chicago, Illinois is subject to bi-directional flows, and density currents are thought to be responsible for these flow variations. This paper presents detailed field measurements using three acoustic Doppler current profiler instruments and simultaneous water-quality measurements made during December 2005. Observations indicate that the formation of density currents within the Chicago River and density differences are mostly due to salinity differences between the North Branch and the main stem of the Chicago River, whereas temperature difference does not appreciably affect the creation of density currents. Sources of higher water temperature, conductivity, and salinity values should be addressed in future studies. ?? 2007 ASCE.

  20. Electron Heat Flux in Pressure Balance Structures at Ulysses

    NASA Technical Reports Server (NTRS)

    Yamauchi, Yohei; Suess, Steven T.; Sakurai, Takashi; Whitaker, Ann F. (Technical Monitor)

    2001-01-01

    Pressure balance structures (PBSs) are a common feature in the high-latitude solar wind near solar minimum. Rom previous studies, PBSs are believed to be remnants of coronal plumes and be related to network activity such as magnetic reconnection in the photosphere. We investigated the magnetic structures of the PBSs, applying a minimum variance analysis to Ulysses/Magnetometer data. At 2001 AGU Spring meeting, we reported that PBSs have structures like current sheets or plasmoids, and suggested that they are associated with network activity at the base of polar plumes. In this paper, we have analyzed high-energy electron data at Ulysses/SWOOPS to see whether bi-directional electron flow exists and confirm the conclusions more precisely. As a result, although most events show a typical flux directed away from the Sun, we have obtained evidence that some PBSs show bi-directional electron flux and others show an isotropic distribution of electron pitch angles. The evidence shows that plasmoids are flowing away from the Sun, changing their flow direction dynamically in a way not caused by Alfven waves. From this, we have concluded that PBSs are generated due to network activity at the base of polar plumes and their magnetic structures axe current sheets or plasmoids.

  1. A novel method for sampling the suspended sediment load in the tidal environment using bi-directional time-integrated mass-flux sediment (TIMS) samplers

    NASA Astrophysics Data System (ADS)

    Elliott, Emily A.; Monbureau, Elaine; Walters, Glenn W.; Elliott, Mark A.; McKee, Brent A.; Rodriguez, Antonio B.

    2017-12-01

    Identifying the source and abundance of sediment transported within tidal creeks is essential for studying the connectivity between coastal watersheds and estuaries. The fine-grained suspended sediment load (SSL) makes up a substantial portion of the total sediment load carried within an estuarine system and efficient sampling of the SSL is critical to our understanding of nutrient and contaminant transport, anthropogenic influence, and the effects of climate. Unfortunately, traditional methods of sampling the SSL, including instantaneous measurements and automatic samplers, can be labor intensive, expensive and often yield insufficient mass for comprehensive geochemical analysis. In estuaries this issue is even more pronounced due to bi-directional tidal flow. This study tests the efficacy of a time-integrated mass sediment sampler (TIMS) design, originally developed for uni-directional flow within the fluvial environment, modified in this work for implementation the tidal environment under bi-directional flow conditions. Our new TIMS design utilizes an 'L' shaped outflow tube to prevent backflow, and when deployed in mirrored pairs, each sampler collects sediment uniquely in one direction of tidal flow. Laboratory flume experiments using dye and particle image velocimetry (PIV) were used to characterize the flow within the sampler, specifically, to quantify the settling velocities and identify stagnation points. Further laboratory tests of sediment indicate that bidirectional TIMS capture up to 96% of incoming SSL across a range of flow velocities (0.3-0.6 m s-1). The modified TIMS design was tested in the field at two distinct sampling locations within the tidal zone. Single-time point suspended sediment samples were collected at high and low tide and compared to time-integrated suspended sediment samples collected by the bi-directional TIMS over the same four-day period. Particle-size composition from the bi-directional TIMS were representative of the array of single time point samples, but yielded greater mass, representative of flow and sediment-concentration conditions at the site throughout the deployment period. This work proves the efficacy of the modified bi-directional TIMS design, offering a novel tool for collection of suspended sediment in the tidally-dominated portion of the watershed.

  2. Liquid crystal dynamic flow control by bidirectional alignment surface

    NASA Astrophysics Data System (ADS)

    Li, Y. W.; Lee, C. Y.; Kwok, H. S.

    2009-02-01

    We investigate the behavior of liquid crystal dynamic flow in a cell with a bidirectional alignment (BDA) surface. Numerical simulations show that with a BDA surface having a pitch comparable to the cell gap d, the liquid crystal dynamic flow direction can be controlled by the driving voltage. Such an effect can be applied to bistable twisted nematic displays without the need for anchoring breaking.

  3. Fiber optic current monitor for high-voltage applications

    DOEpatents

    Renda, G.F.

    1992-04-21

    A current monitor which derives its power from the conductor being measured for bidirectionally measuring the magnitude of current (from DC to above 50 khz) flowing through a conductor across which a relatively high level DC voltage is applied, includes a pair of identical transmitter modules connected in opposite polarity to one another in series with the conductor being monitored, for producing from one module a first light signal having an intensity directly proportional to the magnitude of current flowing in one direction through the conductor during one period of time, and from the other module a second light signal having an intensity directly proportional to the magnitude of current flowing in the opposite direction through the conductor during another period of time, and a receiver located in a safe area remote from the high voltage area for receiving the first and second light signals, and converting the same to first and second voltage signals having levels indicative of the magnitude of current being measured at a given time. 6 figs.

  4. Fiber optic current monitor for high-voltage applications

    DOEpatents

    Renda, George F.

    1992-01-01

    A current monitor which derives its power from the conductor being measured for bidirectionally measuring the magnitude of current (from DC to above 50 khz) flowing through a conductor across which a relatively high level DC voltage is applied, includes a pair of identical transmitter modules connected in opposite polarity to one another in series with the conductor being monitored, for producing from one module a first light signal having an intensity directly proportional to the magnitude of current flowing in one direction through the conductor during one period of time, and from the other module a second light signal having an intensity directly proportional to the magnitude of current flowing in the opposite direction through the conductor during another period of time, and a receiver located in a safe area remote from the high voltage area for receiving the first and second light signals, and converting the same to first and second voltage signals having levels indicative of the magnitude of current being measured at a given time.

  5. Performance and cavitation characteristics of bi-directional hydrofoils

    NASA Astrophysics Data System (ADS)

    Nedyalkov, Ivaylo; Wosnik, Martin

    2013-11-01

    Tidal turbines extract energy from flows which reverse direction. One way to address this bi-directionality in horizontal axis turbines that avoid the use of complex and maintenance-intensive yaw or blade pitch mechanisms, is to design bi-directional blades which perform (equally) well in either flow direction. A large number of proposed hydrofoil designs were investigated using numerical simulations. Selected candidate foils were also tested (at various speeds and angles of attack) in the High-Speed Cavitation Tunnel (HICaT) at the University of New Hampshire. Lift and drag were measured using a force balance, and cavitation inception and desinence were recorded. Experimental and numerical results were compared, and the foils were compared to each other and to reference foils. Bi-directional hydrofoils may provide a feasible solution to the problem of reversing flow direction, when their performance and cavitation characteristics are comparable to those for unidirectional foils, and the penalty in decreased energy production is outweighed by the cost reduction due to lower complexity and respectively lower installation and maintenance costs.

  6. Measuring gravity currents in the Chicago River, Chicago, Illinois

    USGS Publications Warehouse

    Oberg, K.A.; Czuba, J.A.; Johnson, K.K.

    2008-01-01

    Recent studies of the Chicago River have determined that gravity currents are responsible for persistent bidirectional flows that have been observed in the river. A gravity current is the flow of one fluid within another caused by a density difference between the fluids. These studies demonstrated how acoustic Doppler current profilers (ADCP) can be used to detect and characterize gravity currents in the field. In order to better understand the formation and evolution of these gravity currents, the U.S. Geological Survey (USGS) has installed ADCPs and other instruments to continuously measure gravity currents in the Chicago River and the North Branch Chicago River. These instruments include stage sensors, thermistor strings, and both upward-looking and horizontal ADCPs. Data loggers and computers installed at gaging stations along the river are used to collect data from these instruments and transmit them to USGS offices. ?? 2008 IEEE.

  7. Numerical study of MHD nanofluid flow and heat transfer past a bidirectional exponentially stretching sheet

    NASA Astrophysics Data System (ADS)

    Ahmad, Rida; Mustafa, M.; Hayat, T.; Alsaedi, A.

    2016-06-01

    Recent advancements in nanotechnology have led to the discovery of new generation coolants known as nanofluids. Nanofluids possess novel and unique characteristics which are fruitful in numerous cooling applications. Current work is undertaken to address the heat transfer in MHD three-dimensional flow of magnetic nanofluid (ferrofluid) over a bidirectional exponentially stretching sheet. The base fluid is considered as water which consists of magnetite-Fe3O4 nanoparticles. Exponentially varying surface temperature distribution is accounted. Problem formulation is presented through the Maxwell models for effective electrical conductivity and effective thermal conductivity of nanofluid. Similarity transformations give rise to a coupled non-linear differential system which is solved numerically. Appreciable growth in the convective heat transfer coefficient is observed when nanoparticle volume fraction is augmented. Temperature exponent parameter serves to enhance the heat transfer from the surface. Moreover the skin friction coefficient is directly proportional to both magnetic field strength and nanoparticle volume fraction.

  8. Evaluation of cerebral oxygenation and perfusion with conversion from an arterial-to-systemic shunt circulation to the bidirectional Glenn circulation in patients with univentricular cardiac abnormalities.

    PubMed

    Bertolizio, Gianluca; DiNardo, James A; Laussen, Peter C; Polito, Angelo; Pigula, Frank A; Zurakowski, David; Kussman, Barry D

    2015-02-01

    Superior vena cava pressure after the bidirectional Glenn operation usually is higher than that associated with the preceding shunt-dependent circulation. The aim of the present study was to determine whether the acute elevation in central venous pressure was associated with changes in cerebral oxygenation and perfusion. Single-center prospective, observational cohort study. Academic children's hospital. Infants with single-ventricle lesions and surgically placed systemic-to-pulmonary artery shunts undergoing the bidirectional Glenn operation. Near-infrared spectroscopy and transcranial Doppler sonography were used to measure regional cerebral oxygen saturation and cerebral blood flow velocity. Mean differences in regional cerebral oxygen saturation and cerebral blood flow velocity before anesthetic induction and shortly before hospital discharge were compared using the F-test in repeated measures analysis of variance. In the 24 infants studied, mean cerebral oxygen saturation increased from 49%±2% to 57%±2% (p = 0.007), mean cerebral blood flow velocity decreased from 57±4 cm/s to 47±4 cm/s (p = 0.026), and peak systolic cerebral blood flow velocity decreased from 111±6 cm/s to 99±6 cm/s (p = 0.046) after the bidirectional Glenn operation. Mean central venous pressure was 8±2 mmHg postinduction of anesthesia and 14±4 mmHg on the first postoperative day and was not associated with a change in cerebral perfusion pressure (p = 0.35). The bidirectional Glenn operation in infants with a shunt-dependent circulation is associated with an improvement in cerebral oxygenation, and the lower cerebral blood flow velocity is likely a response of intact cerebral autoregulation. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Multi-Cellular 3D Human Primary Liver Cell Cultures Elevate Metabolic Activity Under Fluidic Flow

    PubMed Central

    Esch, Mandy B.; Prot, Jean-Matthieu; Wang, Ying I.; Miller, Paula; Llamas-Vidales, Jose Ricardo; Naughton, Brian A.; Applegate, Dawn R.

    2015-01-01

    Predicting drug-induced liver injury with in vitro cell culture models more accurately would be of significant value to the pharmaceutical industry. To this end we have developed a low-cost liver cell culture device that creates fluidic flow over a 3D primary liver cell culture that consists of multiple liver cell types, including hepatocytes and non-parenchymal cells (fibroblasts, stellate cells, and Kupffer cells). We tested the performance of the cell culture under fluidic flow for 14 days, finding that hepatocytes produced albumin and urea at elevated levels compared to static cultures. Hepatocytes also responded with induction of P450 (CYP1A1 and CYP3A4) enzyme activity when challenged with P450 inducers, although we did not find significant differences between static and fluidic cultures. Non-parenchymal cells were similarly responsive, producing interleukin 8 (IL-8) when challenged with 10 μM bacterial lipoprotein (LPS). To create the fluidic flow in an inexpensive manner, we used a rocking platform that tilts the cell culture devices at angles between ±12°, resulting in a periodically changing hydrostatic pressure drop and bidirectional fluid flow (average flow rate of 650 μL/min, and a maximum shear stress of 0.64 dyne/cm2). The increase in metabolic activity is consistent with the hypothesis that, similar to unidirectional fluidic flow, primary liver cell cultures derived from human tissues increase their metabolic activity in response to bidirectional fluidic flow. Since bidirectional flow drastically changes the behavior of other cells types that are shear sensitive, the finding that bidirectional flow increases the metabolic activity of primary liver cells also supports the theory that this increase in metabolic activity is likely caused by increased levels of gas and metabolite exchange or by the accumulation of soluble growth factors rather than by shear sensing. Our results indicate that device operation with bi-directional gravity-driven medium flow supports the 14-day culture of a mix of primary human liver cells with the benefits of enhanced metabolic activity. Our mode of device operation allows us to evaluate drugs under fluidic cell culture conditions and at low device manufacturing and operation costs. PMID:25857666

  10. Electron Pitch-Angle Distribution in Pressure Balance Structures Measured by Ulysses/SWOOPS

    NASA Technical Reports Server (NTRS)

    Yamauchi, Yohei; Suess, Steven T.; Sakurai, Takashi; Six, N. Frank (Technical Monitor)

    2002-01-01

    Pressure balance structures (PBSs) are a common feature in the high-latitude solar wind near solar minimum. From previous studies, PBSs are believed to be remnants of coronal plumes. Yamauchi et al [2002] investigated the magnetic structures of the PBSs, applying a minimum variance analysis to Ulysses/Magnetometer data. They found that PBSs contain structures like current sheets or plasmoids, and suggested that PBSs are associated with network activity such as magnetic reconnection in the photosphere at the base of polar plumes. We have investigated energetic electron data from Ulysses/SWOOPS to see whether bi-directional electron flow exists and we have found evidence supporting the earlier conclusions. We find that 45 ot of 53 PBSs show local bi-directional or isotopic electron flux or flux associated with current-sheet structure. Only five events show the pitch-angle distribution expected for Alfvenic fluctuations. We conclude that PBSs do contain magnetic structures such as current sheets or plasmoids that are expected as a result of network activity at the base of polar plumes.

  11. Use of acoustic technology to define hydraulic characteristics of an estuary near the Mississippi Gulf Coast

    USGS Publications Warehouse

    Van Wilson, K.

    2004-01-01

    An Acoustic Doppler Current Profiler (ADCP) was used on the Jourdan River at Interstate Highway 10 near Kiln, Mississippi, in 1996 to measure three-dimensional velocity vectors and water depths and in 1998, in combination with a global positioning system, to define channel bathymetry in the vicinity of the bridge. During a 25-hour period on September 19-20, 1996, 117 consecutive measurements of stage and discharge were obtained throughout a complete tidal cycle. These measurements were obtained during the time of year when headwater flows were minimal, and, therefore, the tidal-affected flow conditions were noticeable. The stage ranged from only 0.7 to 2.8 ft above sea level, but discharge ranged from 3,980 ft3/s flowing upstream to 5,580 ft 3/s flowing downstream. The average discharge during the 25-hour period was only 80 ft3/s flowing downstream. By using the ADCP, full downstream flow, bi-directional flow, and full upstream flow conditions were identified. If conventional measurement techniques had been used, the bi-directional flow conditions could not have been detected since flow direction would have been based on what was seen at the water surface. These measurements were used to define the lower range of the stage-storage-volume relation inland of the highway. On June 10, 1998, the ADCP, in combination with a global positional system, was used to define channel bathymetry for the river reach from about 3,500 ft upstream to about 2,500 ft downstream of the bridge. The bathymetry was compared to past soundings obtained in the vicinity of the bridge; as much as 18 ft of total scour was indicated to have occurred at a bridge pier. Copyright ASCE 2004.

  12. System and method for bidirectional flow and controlling fluid flow in a conduit

    DOEpatents

    Ortiz, Marcos German

    1999-01-01

    A system for measuring bidirectional flow, including backflow, of fluid in a conduit. The system utilizes a structural mechanism to create a pressure differential in the conduit. Pressure sensors are positioned upstream from the mechanism, at the mechanism, and downstream from the mechanism. Data from the pressure sensors are transmitted to a microprocessor or computer, and pressure differential detected between the pressure sensors is then used to calculate the backflow. Control signals may then be generated by the microprocessor or computer to shut off valves located in the conduit, upon the occurrence of backflow, or to control flow, total material dispersed, etc. in the conduit.

  13. Safe distance car-following model including backward-looking and its stability analysis

    NASA Astrophysics Data System (ADS)

    Yang, Da; Jin, Peter Jing; Pu, Yun; Ran, Bin

    2013-03-01

    The focus of this paper is the car-following behavior including backward-looking, simply called the bi-directional looking car-following behavior. This study is motivated by the potential changes of the physical properties of traffic flow caused by the fast developing intelligent transportation system (ITS), especially the new connected vehicle technology. Existing studies on this topic focused on general motors (GM) models and optimal velocity (OV) models. The safe distance car-following model, Gipps' model, which is more widely used in practice have not drawn too much attention in the bi-directional looking context. This paper explores the property of the bi-directional looking extension of Gipps' safe distance model. The stability condition of the proposed model is derived using the linear stability theory and is verified using numerical simulations. The impacts of the driver and vehicle characteristics appeared in the proposed model on the traffic flow stability are also investigated. It is found that taking into account the backward-looking effect in car-following has three types of effect on traffic flow: stabilizing, destabilizing and producing non-physical phenomenon. This conclusion is more sophisticated than the study results based on the OV bi-directional looking car-following models. Moreover, the drivers who have the smaller reaction time or the larger additional delay and think the other vehicles have larger maximum decelerations can stabilize traffic flow.

  14. Synaptic activation patterns of the perirhinal-entorhinal inter-connections.

    PubMed

    de Villers-Sidani, E; Tahvildari, B; Alonso, A

    2004-01-01

    Ample neuropsychological evidence supports the role of rhinal cortices in memory. The perirhinal cortex (PRC) represents one of the main conduits for the bi-directional flow of information between the entorhinal-hippocampal network and the cortical mantle, a process essential in memory formation. However, despite anatomical evidence for a robust reciprocal connectivity between the perirhinal and entorhinal cortices, neurophysiological understanding of this circuitry is lacking. We now present the results of a series of electrophysiological experiments in rats that demonstrate robust synaptic activation patterns of the perirhinal-entorhinal inter-connections. First, using silicon multi-electrode arrays placed under visual guidance in vivo we performed current source density (CSD) analysis of lateral entorhinal cortex (LEC) responses to PRC stimulation, which demonstrated a current sink in layers II-III of the LEC with a latency consistent with monosynaptic activation. To further substantiate and extend this conclusion, we developed a PRC-LEC slice preparation where CSD analysis also revealed a current sink in superficial LEC layers in response to PRC stimulation. Importantly, intracellular recording of superficial LEC layer neurons confirmed that they receive a major monosynaptic excitatory input from the PRC. Finally, CSD analysis of the LEC to PRC projection in vivo also allowed us to document robust feedback synaptic activation of PRC neurons to deep LEC layer activation. We conclude that a clear bidirectional pattern of synaptic interactions exists between the PRC and LEC that would support a dynamic flow of information subserving memory function in the temporal lobe.

  15. System and method for bidirectional flow and controlling fluid flow in a conduit

    DOEpatents

    Ortiz, M.G.

    1999-03-23

    A system for measuring bidirectional flow, including backflow, of fluid in a conduit is disclosed. The system utilizes a structural mechanism to create a pressure differential in the conduit. Pressure sensors are positioned upstream from the mechanism, at the mechanism, and downstream from the mechanism. Data from the pressure sensors are transmitted to a microprocessor or computer, and pressure differential detected between the pressure sensors is then used to calculate the backflow. Control signals may then be generated by the microprocessor or computer to shut off valves located in the conduit, upon the occurrence of backflow, or to control flow, total material dispersed, etc. in the conduit. 3 figs.

  16. Power flow controller with a fractionally rated back-to-back converter

    DOEpatents

    Divan, Deepakraj M.; Kandula, Rajendra Prasad; Prasai, Anish

    2016-03-08

    A power flow controller with a fractionally rated back-to-back (BTB) converter is provided. The power flow controller provide dynamic control of both active and reactive power of a power system. The power flow controller inserts a voltage with controllable magnitude and phase between two AC sources at the same frequency; thereby effecting control of active and reactive power flows between the two AC sources. A transformer may be augmented with a fractionally rated bi-directional Back to Back (BTB) converter. The fractionally rated BTB converter comprises a transformer side converter (TSC), a direct-current (DC) link, and a line side converter (LSC). By controlling the switches of the BTB converter, the effective phase angle between the two AC source voltages may be regulated, and the amplitude of the voltage inserted by the power flow controller may be adjusted with respect to the AC source voltages.

  17. Bi-directional transition nets

    NASA Astrophysics Data System (ADS)

    Staines, Anthony Spiteri

    2017-06-01

    Ordinary Petri nets are forward directed transition systems. Modern transition systems events and event flows are reversible. Hence modeling structures that reflect this are important. The creation of a bi-directional Petri net extends the modeling power of Petri nets. This work presents the successful implementation of a bi-directional transition net. Some toy examples in comparison to Petri nets are given showing the increased modeling power in a compacted form. The results show some interesting findings on how the expressive power of these structures has been increased.

  18. Numerical simulation of the flow about the F-18 HARV at high angle of attack

    NASA Technical Reports Server (NTRS)

    Murman, Scott M.

    1994-01-01

    As part of NASA's High Alpha Technology Program, research has been aimed at developing and extending numerical methods to accurately predict the high Reynolds number flow about the NASA F-18 High Alpha Research Vehicle (HARV) at large angles of attack. The HARV aircraft is equipped with a bidirectional thrust vectoring unit which enables stable, controlled flight through 70 deg angle of attack. Currently, high-fidelity numerical solutions for the flow about the HARV have been obtained at alpha = 30 deg, and validated against flight-test data. It is planned to simulate the flow about the HARV through alpha = 60 deg, and obtain solutions of the same quality as those at the lower angles of attack. This report presents the status of work aimed at extending the HARV computations to the extreme angle of attack range.

  19. Formation of a bifurcated current layer by the collision of supersonic magnetized plasmas

    NASA Astrophysics Data System (ADS)

    Suttle, Lee; Hare, Jack; Lebedev, Sergey; Ciardi, Andrea; Loureiro, Nuno; Burdiak, Guy; Chittenden, Jerry; Clayson, Thomas; Ma, Jiming; Niasse, Nicolas; Robinson, Timothy; Smith, Roland; Stuart, Nicolas; Suzuki-Vidal, Francisco

    2016-10-01

    We present detailed experimental data showing the formation and structure of a current layer produced by the collision of two supersonic and well magnetized plasma flows. The pulsed-power driven setup provides two steady and continuous flows, whose embedded magnetic fields mutually annihilate inside the interaction region giving rise to the current layer. Spatially resolved measurements with Faraday rotation polarimetry, Thomson scattering and laser interferometry diagnostics show the detailed distribution of the magnetic field and other plasma parameters throughout the system. We show that the pile-up of magnetic field ahead of the annihilation gives rise to the multi-layered / bi-directional nature of the current sheet, and we discuss pressure balance and energy exchange mechanisms within the system. This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) Grant No. EP/G001324/1, and by the U.S. Department of Energy (DOE) Awards No. DE-F03-02NA00057 and No. DE-SC-0001063.

  20. Bi-directional exchange of membrane components occurs during co-culture of mesenchymal stem cells and nucleus pulposus cells.

    PubMed

    Strassburg, Sandra; Hodson, Nigel W; Hill, Patrick I; Richardson, Stephen M; Hoyland, Judith A

    2012-01-01

    Mesenchymal stem cell (MSC)-based therapies have been proposed as novel treatments for intervertebral disc (IVD) degeneration. We have previously demonstrated that when MSCs are co-cultured with nucleus pulposus (NP) cells with direct cell-cell contact, they differentiate along the NP lineage and simultaneously stimulate the degenerate NP cell population to regain a normal (non-degenerate) phenotype, an effect which requires cell-cell communication. However, the mechanisms by which NP cells and MSCs interact in this system are currently unclear. Thus, in this study we investigated a range of potential mechanisms for exchange of cellular components or information that may direct these changes, including cell fusion, gap-junctional communication and exchange of membrane components by direct transfer or via microvesicle formation. Flow cytometry of fluorescently labeled MSCs and NP cells revealed evidence of some cell fusion and formation of gapjunctions, although at the three timepoints studied these phenomena were detectable only in a small proportion of cells. While these mechanisms may play a role in cell-cell communication, the data suggests they are not the predominant mechanism of interaction. However, flow cytometry of fluorescently dual-labeled cells showed that extensive bi-directional transfer of membrane components is operational during direct co-culture of MSCs and NP cells. Furthermore, there was also evidence for secretion and internalization of membrane-bound microvesicles by both cell types. Thus, this study highlights bi-directional intercellular transfer of membrane components as a possible mechanism of cellular communication between MSC and NP cells.

  1. A Comprehensive Comparison of Current Operating Reserve Methodologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krad, Ibrahim; Ibanez, Eduardo; Gao, Wenzhong

    Electric power systems are currently experiencing a paradigm shift from a traditionally static system to a system that is becoming increasingly more dynamic and variable. Emerging technologies are forcing power system operators to adapt to their performance characteristics. These technologies, such as distributed generation and energy storage systems, have changed the traditional idea of a distribution system with power flowing in one direction into a distribution system with bidirectional flows. Variable generation, in the form of wind and solar generation, also increases the variability and uncertainty in the system. As such, power system operators are revisiting the ways in whichmore » they treat this evolving power system, namely by modifying their operating reserve methodologies. This paper intends to show an in-depth analysis on different operating reserve methodologies and investigate their impacts on power system reliability and economic efficiency.« less

  2. Bidirectional Relationships Between Parenting Processes and Deviance in a Sample of Inner-City African American Youth

    PubMed Central

    Harris, Charlene; Vazsonyi, Alexander T.; Bolland, John M.

    2016-01-01

    The current study assessed for bidirectional relationships among supportive parenting (knowledge), negative parenting (permissiveness), and deviance in a sample (N = 5,325) of poor, inner-city African American youth from the Mobile Youth Survey (MYS) over 4 years. Cross-lagged path analysis provided evidence of significant bidirectional paths among parenting processes (knowledge and permissiveness) and deviance over time. Follow-up multigroup tests provided only modest evidence of dissimilar relationships by sex and by developmental periods. The findings improve our understanding of developmental changes between parenting behaviors and deviance during adolescence and extended current research of the bidirectionality of parent and child relationships among inner-city African American youth. PMID:28316460

  3. Electromagnetically-Actuated Reciprocating Pump for High-Flow-Rate Microfluidic Applications

    PubMed Central

    Ke, Ming-Tsun; Zhong, Jian-Hao; Lee, Chia-Yen

    2012-01-01

    This study presents an electromagnetically-actuated reciprocating pump for high-flow-rate microfluidic applications. The pump comprises four major components, namely a lower glass plate containing a copper microcoil, a middle PMMA plate incorporating a PDMS diaphragm with a surface-mounted magnet, upper PMMA channel plates, and a ball-type check valve located at the channel inlet. When an AC current is passed through the microcoil, an alternating electromagnetic force is established between the coil and the magnet. The resulting bi-directional deflection of the PDMS diaphragm causes the check-valve to open and close; thereby creating a pumping effect. The experimental results show that a coil input current of 0.4 A generates an electromagnetic force of 47 mN and a diaphragm deflection of 108 μm. Given an actuating voltage of 3 V and a driving frequency of 15 Hz, the flow rate is found to be 13.2 mL/min under zero head pressure conditions. PMID:23201986

  4. Fault-tolerant power distribution system

    NASA Technical Reports Server (NTRS)

    Volp, Jeffrey A. (Inventor)

    1987-01-01

    A fault-tolerant power distribution system which includes a plurality of power sources and a plurality of nodes responsive thereto for supplying power to one or more loads associated with each node. Each node includes a plurality of switching circuits, each of which preferably uses a power field effect transistor which provides a diode operation when power is first applied to the nodes and which thereafter provides bi-directional current flow through the switching circuit in a manner such that a low voltage drop is produced in each direction. Each switching circuit includes circuitry for disabling the power field effect transistor when the current in the switching circuit exceeds a preselected value.

  5. Demographic history and gene flow during silkworm domestication

    PubMed Central

    2014-01-01

    Background Gene flow plays an important role in domestication history of domesticated species. However, little is known about the demographic history of domesticated silkworm involving gene flow with its wild relative. Results In this study, four model-based evolutionary scenarios to describe the demographic history of B. mori were hypothesized. Using Approximate Bayesian Computation method and DNA sequence data from 29 nuclear loci, we found that the gene flow at bottleneck model is the most likely scenario for silkworm domestication. The starting time of silkworm domestication was estimated to be approximate 7,500 years ago; the time of domestication termination was 3,984 years ago. Using coalescent simulation analysis, we also found that bi-directional gene flow occurred during silkworm domestication. Conclusions Estimates of silkworm domestication time are nearly consistent with the archeological evidence and our previous results. Importantly, we found that the bi-directional gene flow might occur during silkworm domestication. Our findings add a dimension to highlight the important role of gene flow in domestication of crops and animals. PMID:25123546

  6. Two-dimensional lattice Boltzmann model for magnetohydrodynamics.

    PubMed

    Schaffenberger, Werner; Hanslmeier, Arnold

    2002-10-01

    We present a lattice Boltzmann model for the simulation of two-dimensional magnetohydro dynamic (MHD) flows. The model is an extension of a hydrodynamic lattice Boltzman model with 9 velocities on a square lattice resulting in a model with 17 velocities. Earlier lattice Boltzmann models for two-dimensional MHD used a bidirectional streaming rule. However, the use of such a bidirectional streaming rule is not necessary. In our model, the standard streaming rule is used, allowing smaller viscosities. To control the viscosity and the resistivity independently, a matrix collision operator is used. The model is then applied to the Hartmann flow, giving reasonable results.

  7. Bidirectional current triggering in planar devices based on serially connected VO2 thin films using 965 nm laser diode.

    PubMed

    Kim, Jihoon; Park, Kyongsoo; Kim, Bong-Jun; Lee, Yong Wook

    2016-08-08

    By incorporating a 965 nm laser diode, the bidirectional current triggering of up to 30 mA was demonstrated in a two-terminal planar device based on serially connected vanadium dioxide (VO2) thin films grown by pulsed laser deposition. The bidirectional current triggering was realized by using the focused beams of laser pulses through the photo-thermally induced phase transition of VO2. The transient responses of laser-triggered currents were also investigated when laser pulses excited the device at a variety of pulse widths and repetition rates of up to 4.0 Hz. A switching contrast between off- and on-state currents was obtained as ~8333, and rising and falling times were measured as ~39 and ~29 ms, respectively, for 50 ms laser pulses.

  8. The CTSA mandate: are we there yet?

    PubMed

    Sampselle, Carolyn M; Pienta, Kenneth J; Markel, Dorene S

    2010-01-01

    The ultimate aim of the National Institutes of Health Clinical and Translational Science Award (CTSA) initiative is to accelerate the movement of discoveries that can benefit human health into widespread public use. To accomplish this translational mandate, the contributions of multiple disciplines, such as dentistry, nursing, pharmacy, public health, biostatistics, epidemiology, and bioengineering, are required in addition to medicine. The research community is also mandated to establish new partnerships with organized patient communities and front line health care providers to assure the bidirectional flow of information in order that health priorities experienced by the community inform the research agenda. This article summarizes current clinical research directives, the experience of the University of Michigan faculty during the first 2 years of CTSA support, and recommendations to enhance the effectiveness of future CTSA as well as other interdisciplinary initiatives. While the manuscript focuses most closely on the CTSA Community Engagement mission, the challenges to interdisciplinarity and bidirectionality extend beyond the focus of community engagement.

  9. Superconducting analog-to-digital converter with a triple-junction reversible flip-flop bidirectional counter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, G.S.

    1993-07-13

    A high-performance superconducting analog-to-digital converter is described, comprising: a bidirectional binary counter having n stages of triple-junction reversible flip-flops connected together in a cascade arrangement from the least significant bit (LSB) to the most significant bit (MSB) where n is the number of bits of the digital output, each triple-junction reversible flip-flop including first, second and third shunted Josephson tunnel junctions and a superconducting inductor connected in a bridge circuit, the Josephson junctions and the inductor forming upper and lower portions of the flip-flop, each reversible flip-flop being a bistable logic circuit in which the direction of the circulating currentmore » determines the state of the circuit; and means for applying an analog input current to the bidirectional counter; wherein the bidirectional counter algebraically counts incremental changes in the analog input current, increasing the binary count for positive incremental changes in the analog current and decreasing the binary count for negative incremental changes in the current, and wherein the counter does not require a gate bias, thus minimizing power dissipation.« less

  10. A lab-in-a-droplet bioassay strategy for centrifugal microfluidics with density difference pumping, power to disc and bidirectional flow control.

    PubMed

    Wang, Guanghui; Ho, Ho-Pui; Chen, Qiulan; Yang, Alice Kar-Lai; Kwok, Ho-Chin; Wu, Shu-Yuen; Kong, Siu-Kai; Kwan, Yiu-Wa; Zhang, Xuping

    2013-09-21

    In this paper, we present a lab-in-a-droplet bioassay strategy for a centrifugal microfluidics or lab-on-a-disc (LOAD) platform with three important advancements including density difference pumping, power to disc and bidirectional flow control. First, with the water based bioassay droplets trapped in a micro-channel filled with mineral oil, centrifugal force due to the density difference between the water and oil phases actuates droplet movement while the oil based medium remains stationary. Second, electricity is coupled to the rotating disc through a split-core transformer, thus enabling on-chip real-time heating in selected areas as desired and wireless programmable functionality. Third, an inertial mechanical structure is proposed to achieve bidirectional flow control within the spinning disc. The droplets can move back and forth between two heaters upon changing the rotational speed. Our platform is an essential and versatile solution for bioassays such as those involving DNA amplification, where localized temperature cycling is required. Finally, without the loss of generality, we demonstrate the functionality of our platform by performing real-time polymerase chain reaction (RT-PCR) in a linear microchannel made with PTFE (Teflon) micro-tubing.

  11. An air flow sensor for neonatal mechanical ventilation applications based on a novel fiber-optic sensing technique.

    PubMed

    Battista, L; Sciuto, S A; Scorza, A

    2013-03-01

    In this work, a simple and low-cost air flow sensor, based on a novel fiber-optic sensing technique has been developed for monitoring air flows rates supplied by a neonatal ventilator to support infants in intensive care units. The device is based on a fiber optic sensing technique allowing (a) the immunity to light intensity variations independent by measurand and (b) the reduction of typical shortcomings affecting all biomedical fields (electromagnetic interference and patient electrical safety). The sensing principle is based on the measurement of transversal displacement of an emitting fiber-optic cantilever due to action of air flow acting on it; the fiber tip displacement is measured by means of a photodiode linear array, placed in front of the entrance face of the emitting optical fiber in order to detect its light intensity profile. As the measurement system is based on a detection of the illumination pattern, and not on an intensity modulation technique, it results less sensitive to light intensity fluctuation independent by measurand than intensity-based sensors. The considered technique is here adopted in order to develop two different configurations for an air flow sensor suitable for the measurement of air flow rates typically occurring during mechanical ventilation of newborns: a mono-directional and a bi-directional transducer have been proposed. A mathematical model for the air flow sensor is here proposed and a static calibration of two different arrangements has been performed: a measurement range up to 3.00 × 10(-4) m(3)∕s (18.0 l∕min) for the mono-directional sensor and a measurement range of ±3.00 × 10(-4) m(3)∕s (±18.0 l∕min) for the bi-directional sensor are experimentally evaluated, according to the air flow rates normally encountered during tidal breathing of infants with a mass lower than 10 kg. Experimental data of static calibration result in accordance with the proposed theoretical model: for the mono-directional configuration, the coefficient of determination r(2) is equal to 0.997; for the bi-directional configuration, the coefficient of determination r(2) is equal to 0.990 for positive flows (inspiration) and 0.988 for negative flows (expiration). Measurement uncertainty δQ of air flow rate has been evaluated by means of the propagation of distributions and the percentage error in the arrangement of bi-directional sensor ranges from a minimum of about 0.5% at -18.0 l∕min to a maximum of about 9% at -12.0 l∕min.

  12. An air flow sensor for neonatal mechanical ventilation applications based on a novel fiber-optic sensing technique

    NASA Astrophysics Data System (ADS)

    Battista, L.; Sciuto, S. A.; Scorza, A.

    2013-03-01

    In this work, a simple and low-cost air flow sensor, based on a novel fiber-optic sensing technique has been developed for monitoring air flows rates supplied by a neonatal ventilator to support infants in intensive care units. The device is based on a fiber optic sensing technique allowing (a) the immunity to light intensity variations independent by measurand and (b) the reduction of typical shortcomings affecting all biomedical fields (electromagnetic interference and patient electrical safety). The sensing principle is based on the measurement of transversal displacement of an emitting fiber-optic cantilever due to action of air flow acting on it; the fiber tip displacement is measured by means of a photodiode linear array, placed in front of the entrance face of the emitting optical fiber in order to detect its light intensity profile. As the measurement system is based on a detection of the illumination pattern, and not on an intensity modulation technique, it results less sensitive to light intensity fluctuation independent by measurand than intensity-based sensors. The considered technique is here adopted in order to develop two different configurations for an air flow sensor suitable for the measurement of air flow rates typically occurring during mechanical ventilation of newborns: a mono-directional and a bi-directional transducer have been proposed. A mathematical model for the air flow sensor is here proposed and a static calibration of two different arrangements has been performed: a measurement range up to 3.00 × 10-4 m3/s (18.0 l/min) for the mono-directional sensor and a measurement range of ±3.00 × 10-4 m3/s (±18.0 l/min) for the bi-directional sensor are experimentally evaluated, according to the air flow rates normally encountered during tidal breathing of infants with a mass lower than 10 kg. Experimental data of static calibration result in accordance with the proposed theoretical model: for the mono-directional configuration, the coefficient of determination r2 is equal to 0.997; for the bi-directional configuration, the coefficient of determination r2 is equal to 0.990 for positive flows (inspiration) and 0.988 for negative flows (expiration). Measurement uncertainty δQ of air flow rate has been evaluated by means of the propagation of distributions and the percentage error in the arrangement of bi-directional sensor ranges from a minimum of about 0.5% at -18.0 l/min to a maximum of about 9% at -12.0 l/min.

  13. A Review of 25 Years of Research in Bidirectionality in Parent-Child Relationships: An Examination of Methodological Approaches

    ERIC Educational Resources Information Center

    Paschall, Katherine W.; Mastergeorge, Ann M.

    2016-01-01

    The concept of bidirectionality represents a process of mutual influence between parent and child, whereby each influences the other as well as the dyadic relationship. Despite the widespread acceptance of bidirectional models of influence, there is still a lack of integration of such models in current research designs. Research on…

  14. Adhesion signals of phospholipid vesicles at an electrified interface.

    PubMed

    DeNardis, Nadica Ivošević; Žutić, Vera; Svetličić, Vesna; Frkanec, Ruža

    2012-09-01

    General adhesion behavior of phospholipid vesicles was examined in a wide range of potentials at the mercury electrode by recording time-resolved adhesion signals. It was demonstrated that adhesion-based detection is sensitive to polar headgroups in phospholipid vesicles. We identified a narrow potential window around the point of zero charge of the electrode where the interaction of polar headgroups of phosphatidylcholine vesicles with the substrate is manifested in the form of bidirectional signals. The bidirectional signal is composed of the charge flow due to the nonspecific interaction of vesicle adhesion and spreading and of the charge flow due to a specific interaction of the negatively charged electrode and the most exposed positively charged choline headgroups. These signals are expected to appear only when the electrode surface charge density is less than the surface charge density of the choline groups at the contact interface. In comparison, for the negatively charged phosphatidylserine vesicles, we identified the potential window at the mercury electrode where charge compensation takes place, and bidirectional signals were not detected.

  15. Bottleneck effects on the bidirectional crowd dynamics

    NASA Astrophysics Data System (ADS)

    Yang, Xiao-Xia; Dong, Hai-Rong; Yao, Xiu-Ming; Sun, Xu-Bin

    2016-12-01

    The bottleneck effect on bidirectional crowd dynamics is of great theoretical and practical significance, especially for the designing of corridors in public places, such as subway stations or airports. Based on the famous social force model, this paper investigates the bottleneck effects on the free flow dynamics and breakdown phenomenon under different scenarios, in which different corridor shapes and inflow ratios are considered simultaneously. Numerical simulation finds an interesting self-organization phenomenon in the bidirectional flow, a typical characteristic of such a phenomenon is called lane formation, and the existence of which is independent of the corridor’s shape and inflow rate. However, the pattern of the lane formed by pedestrian flow is related to the corridor’s shape, and the free flow efficiency has close relationship with the inflow rate. Specifically, breakdown phenomenon occurs when inflows from both sides of the corridor are large enough, which mostly originates from the bottleneck and then gradually spreads to the other regions. Simulation results further indicate that the leaving efficiency becomes low as breakdown occurs, and the degree of congestion is proportional to the magnitude of inflow. The findings presented in this paper match well with some of our daily observations, hence it is possible to use them to provide us with theoretical suggestions in design of infrastructures. Project supported jointly by the National Natural Science Foundation of China (Grant Nos. 61322307 and 2016YJS023).

  16. Influence of nonlinear thermal radiation and viscous dissipation on three-dimensional flow of Jeffrey nano fluid over a stretching sheet in the presence of Joule heating

    NASA Astrophysics Data System (ADS)

    Ganesh Kumar, K.; Rudraswamy, N. G.; Gireesha, B. J.; Krishnamurthy, M. R.

    2017-09-01

    Present exploration discusses the combined effect of viscous dissipation and Joule heating on three dimensional flow and heat transfer of a Jeffrey nanofluid in the presence of nonlinear thermal radiation. Here the flow is generated over bidirectional stretching sheet in the presence of applied magnetic field by accounting thermophoresis and Brownian motion of nanoparticles. Suitable similarity transformations are employed to reduce the governing partial differential equations into coupled nonlinear ordinary differential equations. These nonlinear ordinary differential equations are solved numerically by using the Runge-Kutta-Fehlberg fourth-fifth order method with shooting technique. Graphically results are presented and discussed for various parameters. Validation of the current method is proved by comparing our results with the existing results under limiting situations. It can be concluded that combined effect of Joule and viscous heating increases the temperature profile and thermal boundary layer thickness.

  17. Bidirectional reflectance function in coastal waters: modeling and validation

    NASA Astrophysics Data System (ADS)

    Gilerson, Alex; Hlaing, Soe; Harmel, Tristan; Tonizzo, Alberto; Arnone, Robert; Weidemann, Alan; Ahmed, Samir

    2011-11-01

    The current operational algorithm for the correction of bidirectional effects from the satellite ocean color data is optimized for typical oceanic waters. However, versions of bidirectional reflectance correction algorithms, specifically tuned for typical coastal waters and other case 2 conditions, are particularly needed to improve the overall quality of those data. In order to analyze the bidirectional reflectance distribution function (BRDF) of case 2 waters, a dataset of typical remote sensing reflectances was generated through radiative transfer simulations for a large range of viewing and illumination geometries. Based on this simulated dataset, a case 2 water focused remote sensing reflectance model is proposed to correct above-water and satellite water leaving radiance data for bidirectional effects. The proposed model is first validated with a one year time series of in situ above-water measurements acquired by collocated multi- and hyperspectral radiometers which have different viewing geometries installed at the Long Island Sound Coastal Observatory (LISCO). Match-ups and intercomparisons performed on these concurrent measurements show that the proposed algorithm outperforms the algorithm currently in use at all wavelengths.

  18. A Bidirectional High-Power-Quality Grid Interface With a Novel Bidirectional Noninverted Buck Boost Converter for PHEVs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Onar, Omer C

    2012-01-01

    Plug-in hybrid electric vehicles (PHEVs) will play a vital role in future sustainable transportation systems due to their potential in terms of energy security, decreased environmental impact, improved fuel economy, and better performance. Moreover, new regulations have been established to improve the collective gas mileage, cut greenhouse gas emissions, and reduce dependence on foreign oil. This paper primarily focuses on two major thrust areas of PHEVs. First, it introduces a grid-friendly bidirectional alternating current/direct current ac/dc dc/ac rectifier/inverter for facilitating vehicle-to-grid (V2G) integration of PHEVs. Second, it presents an integrated bidirectional noninverted buck boost converter that interfaces the energy storagemore » device of the PHEV to the dc link in both grid-connected and driving modes. The proposed bidirectional converter has minimal grid-level disruptions in terms of power factor and total harmonic distortion, with less switching noise. The integrated bidirectional dc/dc converter assists the grid interface converter to track the charge/discharge power of the PHEV battery. In addition, while driving, the dc/dc converter provides a regulated dc link voltage to the motor drive and captures the braking energy during regenerative braking.« less

  19. Evolution of the optimum bidirectional (+/- biphasic) wave for defibrillation.

    PubMed

    Geddes, L A; Havel, W

    2000-01-01

    Introduction of the asymmetric bidirectional (+/- biphasic) current waveform has made it possible to achieve ventricular defibrillation with less energy and current than are needed with a unidirectional (monophasic) waveform. The symmetrical bidirectional (sinusoidal) waveform was used for the first human-heart defibrillation. Subsequent studies employed the underdamped and overdamped sine waves, then the trapezoidal (monophasic) wave. Studies were then undertaken to investigate the benefit of adding a second identical and inverted wave; little success rewarded these efforts until it was discovered that the second inverted wave needed to be much less in amplitude to lower the threshold for defibrillation. However, there is no physiologic theory that explains the mechanism of action of the bidirectional wave, nor does any theory predict the optimum amplitude and time dimensions for the second inverted wave. The authors analyze the research that shows that the threshold defibrillation energy is lowest when the charge in the second, inverted phase is slightly more than a third of that in the first phase. An ion-flux, spatial-K+ summation hypothesis is presented that shows the effect on myocardial cells of adding the second inverted current pulse.

  20. A Phase 1 Study of a Novel Bidirectional Perfusion Cannula in Patients Undergoing Femoral Cannulation for Cardiac Surgery.

    PubMed

    Marasco, Silvana F; Tutungi, Elli; Vallance, Shirley A; Udy, Andrew A; Negri, Justin C; Zimmet, Adam D; McGiffin, David C; Pellegrino, Vincent A; Moshinsky, Randall A

    Leg ischemia is a serious complication of femoral artery cannulation. The primary aim of this study was to assess the safety and efficacy of a novel bidirectional femoral arterial cannula (Sorin Group USA, a wholly owned subsidiary of LivaNova PLC, Arvada, CO USA) that provides both antegrade and retrograde flow, in patients undergoing peripheral cannulation for cardiopulmonary bypass during cardiac surgery. Patients undergoing routine cardiac surgery requiring femoral artery cannulation for cardiopulmonary bypass were identified preoperatively. Informed written consent was obtained in all cases. Bidirectional cannula insertion used either a surgical cut-down and wire through needle approach or a percutaneous technique. Flow in the superficial femoral artery was assessed using Doppler ultrasound after commencement of cardiopulmonary bypass. Lower limb perfusion was assessed using reflectance near-infrared spectroscopy to measure regional oxygen saturations in the cannulated limb during cardiopulmonary bypass. Fifteen patients (median age = 61.3 years, range = 26-79 years, 10 males, 5 females) underwent femoral arterial cannulation using the novel bidirectional femoral cannula between August 2016 and May 2017. Fourteen cannulae were inserted directly into the femoral artery via a surgical cut-down and wire through needle technique. One bidirectional cannula was inserted using a percutaneous insertion technique. Indications included minimally invasive mitral and aortic valve surgery, thoracic aortic aneurysm repair, and redo cardiac surgery. The median duration of cardiopulmonary bypass was 129 minutes (range = 53-228 minutes). The cannula was inserted and positioned without difficulty in 14 of 15 patients. Incorrect sizing and arterial spasm prevented correct cannula positioning in one patient. Antegrade flow in the superficial femoral artery was observed on Doppler ultrasound in 12 of 12 patients in which this was performed. Continuous stable distal perfusion was demonstrated in the cannulated limb in 14 of 15 patients. No procedural complications occurred in the immediate or convalescent postoperative period. This study demonstrates that in patients undergoing femoral arterial cannulation for cardiopulmonary bypass during cardiac surgery, the use of a novel bidirectional cannula is safe and easy to insert and provides stable distal perfusion of the cannulated limb. Use of the device should largely obviate the need to insert a separate downstream perfusion cannula or use other techniques to protect against lower limb ischemia. Further research on a larger scale and in different patient populations is now warranted.

  1. An air flow sensor for neonatal mechanical ventilation applications based on a novel fiber-optic sensing technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Battista, L.; Sciuto, S. A.; Scorza, A.

    2013-03-15

    In this work, a simple and low-cost air flow sensor, based on a novel fiber-optic sensing technique has been developed for monitoring air flows rates supplied by a neonatal ventilator to support infants in intensive care units. The device is based on a fiber optic sensing technique allowing (a) the immunity to light intensity variations independent by measurand and (b) the reduction of typical shortcomings affecting all biomedical fields (electromagnetic interference and patient electrical safety). The sensing principle is based on the measurement of transversal displacement of an emitting fiber-optic cantilever due to action of air flow acting on it;more » the fiber tip displacement is measured by means of a photodiode linear array, placed in front of the entrance face of the emitting optical fiber in order to detect its light intensity profile. As the measurement system is based on a detection of the illumination pattern, and not on an intensity modulation technique, it results less sensitive to light intensity fluctuation independent by measurand than intensity-based sensors. The considered technique is here adopted in order to develop two different configurations for an air flow sensor suitable for the measurement of air flow rates typically occurring during mechanical ventilation of newborns: a mono-directional and a bi-directional transducer have been proposed. A mathematical model for the air flow sensor is here proposed and a static calibration of two different arrangements has been performed: a measurement range up to 3.00 Multiplication-Sign 10{sup -4} m{sup 3}/s (18.0 l/min) for the mono-directional sensor and a measurement range of {+-}3.00 Multiplication-Sign 10{sup -4} m{sup 3}/s ({+-}18.0 l/min) for the bi-directional sensor are experimentally evaluated, according to the air flow rates normally encountered during tidal breathing of infants with a mass lower than 10 kg. Experimental data of static calibration result in accordance with the proposed theoretical model: for the mono-directional configuration, the coefficient of determination r{sup 2} is equal to 0.997; for the bi-directional configuration, the coefficient of determination r{sup 2} is equal to 0.990 for positive flows (inspiration) and 0.988 for negative flows (expiration). Measurement uncertainty {delta}Q of air flow rate has been evaluated by means of the propagation of distributions and the percentage error in the arrangement of bi-directional sensor ranges from a minimum of about 0.5% at -18.0 l/min to a maximum of about 9% at -12.0 l/min.« less

  2. Probing Reliability of Transport Phenomena Based Heat Transfer and Fluid Flow Analysis in Autogeneous Fusion Welding Process

    NASA Astrophysics Data System (ADS)

    Bag, S.; de, A.

    2010-09-01

    The transport phenomena based heat transfer and fluid flow calculations in weld pool require a number of input parameters. Arc efficiency, effective thermal conductivity, and viscosity in weld pool are some of these parameters, values of which are rarely known and difficult to assign a priori based on the scientific principles alone. The present work reports a bi-directional three-dimensional (3-D) heat transfer and fluid flow model, which is integrated with a real number based genetic algorithm. The bi-directional feature of the integrated model allows the identification of the values of a required set of uncertain model input parameters and, next, the design of process parameters to achieve a target weld pool dimension. The computed values are validated with measured results in linear gas-tungsten-arc (GTA) weld samples. Furthermore, a novel methodology to estimate the overall reliability of the computed solutions is also presented.

  3. Helical solutions of the bidirectional vortex in a cylindrical cyclone: Beltramian and Trkalian motions

    NASA Astrophysics Data System (ADS)

    Majdalani, Joseph

    2012-10-01

    In this work, two families of helical motions are investigated as prospective candidates for describing the bidirectional vortex field in a right-cylindrical chamber. These basic solutions are relevant to cyclone separators and to idealized representations of vortex-fired liquid and hybrid rocket engines in which bidirectional vortex motion is established. To begin, the bulk fluid motion is taken to be isentropic along streamlines, with no concern for reactions, heat transfer, viscosity, compressibility or unsteadiness. Then using the Bragg-Hawthorne equation for steady, inviscid, axisymmetric motion, two families of Euler solutions are derived. Among the characteristics of the newly developed solutions one may note the axial dependence of the swirl velocity, the Trkalian and Beltramian types of the helical motions, the sensitivity of the solutions to the outlet radius, the alternate locations of the mantle, and the increased axial and radial velocity magnitudes, including the rate of mass transfer across the mantle, for which explicit approximations are obtained. Our results are compared to an existing, complex lamellar model of the bidirectional vortex in which the swirl velocity reduces to a free vortex. In this vein, we find the strictly Beltramian flows to share virtually identical pressure variations and radial pressure gradients with those associated with the complex lamellar motion. Furthermore, both families warrant an asymptotic treatment to overcome their endpoint limitations caused by their omission of viscous stresses. From a broader perspective, the work delineates a logical framework through which self-similar, axisymmetric solutions to bidirectional and multidirectional vortex motions may be pursued. It also illustrates the manner through which different formulations may be arrived at depending on the types of wall boundary conditions. For example, both the slip condition at the sidewall and the inlet flow pattern at the headwall may be enforced or relaxed.

  4. Assessment of a Bidirectional Reflectance Distribution Correction of Above-Water and Satellite Water-Leaving Radiance in Coastal Waters

    NASA Technical Reports Server (NTRS)

    Hlaing, Soe; Gilerson, Alexander; Harmal, Tristan; Tonizzo, Alberto; Weidemann, Alan; Arnone, Robert; Ahmed, Samir

    2012-01-01

    Water-leaving radiances, retrieved from in situ or satellite measurements, need to be corrected for the bidirectional properties of the measured light in order to standardize the data and make them comparable with each other. The current operational algorithm for the correction of bidirectional effects from the satellite ocean color data is optimized for typical oceanic waters. However, versions of bidirectional reflectance correction algorithms specifically tuned for typical coastal waters and other case 2 conditions are particularly needed to improve the overall quality of those data. In order to analyze the bidirectional reflectance distribution function (BRDF) of case 2 waters, a dataset of typical remote sensing reflectances was generated through radiative transfer simulations for a large range of viewing and illumination geometries. Based on this simulated dataset, a case 2 water focused remote sensing reflectance model is proposed to correct above-water and satellite water-leaving radiance data for bidirectional effects. The proposed model is first validated with a one year time series of in situ above-water measurements acquired by collocated multispectral and hyperspectral radiometers, which have different viewing geometries installed at the Long Island Sound Coastal Observatory (LISCO). Match-ups and intercomparisons performed on these concurrent measurements show that the proposed algorithm outperforms the algorithm currently in use at all wavelengths, with average improvement of 2.4% over the spectral range. LISCO's time series data have also been used to evaluate improvements in match-up comparisons of Moderate Resolution Imaging Spectroradiometer satellite data when the proposed BRDF correction is used in lieu of the current algorithm. It is shown that the discrepancies between coincident in-situ sea-based and satellite data decreased by 3.15% with the use of the proposed algorithm.

  5. A mathematical model and computational framework for three-dimensional chondrocyte cell growth in a porous tissue scaffold placed inside a bi-directional flow perfusion bioreactor.

    PubMed

    Shakhawath Hossain, Md; Bergstrom, D J; Chen, X B

    2015-12-01

    The in vitro chondrocyte cell culture for cartilage tissue regeneration in a perfusion bioreactor is a complex process. Mathematical modeling and computational simulation can provide important insights into the culture process, which would be helpful for selecting culture conditions to improve the quality of the developed tissue constructs. However, simulation of the cell culture process is a challenging task due to the complicated interaction between the cells and local fluid flow and nutrient transport inside the complex porous scaffolds. In this study, a mathematical model and computational framework has been developed to simulate the three-dimensional (3D) cell growth in a porous scaffold placed inside a bi-directional flow perfusion bioreactor. The model was developed by taking into account the two-way coupling between the cell growth and local flow field and associated glucose concentration, and then used to perform a resolved-scale simulation based on the lattice Boltzmann method (LBM). The simulation predicts the local shear stress, glucose concentration, and 3D cell growth inside the porous scaffold for a period of 30 days of cell culture. The predicted cell growth rate was in good overall agreement with the experimental results available in the literature. This study demonstrates that the bi-directional flow perfusion culture system can enhance the homogeneity of the cell growth inside the scaffold. The model and computational framework developed is capable of providing significant insight into the culture process, thus providing a powerful tool for the design and optimization of the cell culture process. © 2015 Wiley Periodicals, Inc.

  6. Experimental Discussion on a 6-kW, 2-kWh Battery Energy Storage System Using a Bidirectional Isolated DC/DC Converter

    NASA Astrophysics Data System (ADS)

    Abe, Takahiro; Tan, Nadia Mei Lin; Akagi, Hirofumi

    This paper presents an experimental discussion on a 6-kW, full-bridge, zero-voltage switching bidirectional isolated dc/dc converter for a 53.2-V, 2-kWh Li-ion battery energy storage system. The combination of high-frequency switching devices, 600-V/200-A IGBTs and 100-V/500-A MOSFETs with a high-frequency transformer reduces the weight and physical size of the bidirectional isolated dc/dc converter. The dc voltage on the high-voltage side of the converter is controlled in a range of 300V to 355V as the battery voltage on the low-voltage side varies from 50V to 59V. Experimental verification of bidirectional power flow into (battery charging) or out of (battery discharging) the Li-ion battery bank is also presented. The maximal efficiency of the dc/dc converter is measured to be 98.1% during charging and 98.2% during discharging, excluding the gate drive loss and control circuit loss.

  7. Assessment of a bidirectional reflectance distribution correction of above-water and satellite water-leaving radiance in coastal waters.

    PubMed

    Hlaing, Soe; Gilerson, Alexander; Harmel, Tristan; Tonizzo, Alberto; Weidemann, Alan; Arnone, Robert; Ahmed, Samir

    2012-01-10

    Water-leaving radiances, retrieved from in situ or satellite measurements, need to be corrected for the bidirectional properties of the measured light in order to standardize the data and make them comparable with each other. The current operational algorithm for the correction of bidirectional effects from the satellite ocean color data is optimized for typical oceanic waters. However, versions of bidirectional reflectance correction algorithms specifically tuned for typical coastal waters and other case 2 conditions are particularly needed to improve the overall quality of those data. In order to analyze the bidirectional reflectance distribution function (BRDF) of case 2 waters, a dataset of typical remote sensing reflectances was generated through radiative transfer simulations for a large range of viewing and illumination geometries. Based on this simulated dataset, a case 2 water focused remote sensing reflectance model is proposed to correct above-water and satellite water-leaving radiance data for bidirectional effects. The proposed model is first validated with a one year time series of in situ above-water measurements acquired by collocated multispectral and hyperspectral radiometers, which have different viewing geometries installed at the Long Island Sound Coastal Observatory (LISCO). Match-ups and intercomparisons performed on these concurrent measurements show that the proposed algorithm outperforms the algorithm currently in use at all wavelengths, with average improvement of 2.4% over the spectral range. LISCO's time series data have also been used to evaluate improvements in match-up comparisons of Moderate Resolution Imaging Spectroradiometer satellite data when the proposed BRDF correction is used in lieu of the current algorithm. It is shown that the discrepancies between coincident in-situ sea-based and satellite data decreased by 3.15% with the use of the proposed algorithm. This confirms the advantages of the proposed model over the current one, demonstrating the need for a specific case 2 water BRDF correction algorithm as well as the feasibility of enhancing performance of current and future satellite ocean color remote sensing missions for monitoring of typical coastal waters. © 2012 Optical Society of America

  8. Assessment of a Bidirectional Reflectance Distribution Correction of Above-Water and Satellite Water-Leaving Radiance in Coastal Waters

    DTIC Science & Technology

    2012-01-10

    water and satellite water-leaving radiance data for bidirectional effects. The proposed model is first validated with a one year time series of in situ... model is proposed to correct above-water and satellite water-leaving radiance data for bidirectional effects. The proposed model is first validated with...proposed model over the current one, demonstrating the need for a specific case 2 water BRDF correction algorithm as well as the feasibility of enhancing

  9. Calf pump activity influencing venous hemodynamics in the lower extremity.

    PubMed

    Recek, Cestmir

    2013-03-01

    Calf muscle pump is the motive force enhancing return of venous blood from the lower extremity to the heart. It causes displacement of venous blood in both vertical and horizontal directions, generates ambulatory pressure gradient between thigh and lower leg veins, and bidirectional streaming within calf perforators. Ambulatory pressure gradient triggers venous reflux in incompetent veins, which induces ambulatory venous hypertension in the lower leg and foot. Bidirectional flow in calf perforators enables quick pressure equalization between deep and superficial veins of the lower leg; the outward (into the superficial veins) oriented component of the bidirectional flow taking place during calf muscle contraction is no pathological reflux but a physiological centripetal flow streaming via great saphenous vein into the femoral vein. Calf perforators are communicating channels between both systems making them conjoined vessels; they are not involved in the generation of pathological hemodynamic situations, nor do they cause ambulatory venous hypertension. The real cause why recurrences develop has not as yet been cleared. Pressure gradient arising during calf pump activity between the femoral vein and the saphenous remnant after abolition of saphenous reflux triggers biophysical and biochemical events, which might induce recurrence. Thus, abolition of saphenous reflux removes the hemodynamic disturbance, but at the same time it generates precondition for reflux recurrence and for the comeback of the previous pathological situation; this chain of events has been called hemodynamic paradox.

  10. Investigation of PVdF active diaphragms for synthetic jets

    NASA Astrophysics Data System (ADS)

    Bailo, Kelly C.; Brei, Diann E.; Calkins, Frederick T.

    2000-06-01

    Current research has shown that aircraft can gain significant aerodynamic performance benefits by employing active flow control (AFC). One of the enabling technologies of AFC is the synthetic jet. Synthetic jets, also known as zero-net-mass flux actuators, act as bi-directional pumps injecting high momentum air into the local aerodynamic flow. Previous work has concentrated on high frequency synthetic jets based on piezoelectric active diaphragms such as Thunder actuators. Low frequency synthetic jets present a unique challenge requiring large displacements, which current technology has difficulty meeting. Boeing is investigating novel shaped low frequency synthetic jets that can modify the flow over fixed aircraft wings. This paper present the initial study of two promising active diaphragm concepts: a crescent shape and an opposing bender shape. These active diaphragms were numerically modeled utilizing the general-purpose finite element code ABAQUS. Using the ABAQUS results, the dynamic volume change within each jet was calculated and incorporated into an analytical linear Bernoulli model to predict the velocities and pressures at the nozzle. Simulations were performed to determine trends to assist in selection of prototype configurations. Prototypes of both diaphragm concepts were constructed from polyvinylidene fluoride and experimentally tested at Boeing with promising results.

  11. Systems and methods for commutating inductor current using a matrix converter

    DOEpatents

    Ransom, Ray M; Kajouke, Lateef A; Perisic, Milun

    2012-10-16

    Systems and methods are provided for delivering current using a matrix converter in a vehicle. An electrical system comprises an AC interface, a first conversion module coupled to the AC interface, an inductive element coupled between the AC interface and the first conversion module, and a control module coupled to the first conversion module. The control module is configured to operate the first conversion module in a bidirectional operating mode to commutate current bidirectionally. When a magnitude of the current through the inductive element is greater than a first threshold value, the control module operates the conversion module in a unidirectional operating mode, wherein current is commutated unidirectionally.

  12. Bidirectional dc-to-dc Power Converter

    NASA Technical Reports Server (NTRS)

    Griesbach, C. R.

    1986-01-01

    Solid-state, series-resonant converter uses high-voltage thyristors. Converter used either to convert high-voltage, low-current dc power to lowvoltage, high current power or reverse. Taking advantage of newly-available high-voltage thyristors to provide better reliability and efficiency than traditional converters that use vacuum tubes as power switches. New converter essentially maintenance free and provides greatly increased mean time between failures. Attractive in industrial applications whether or not bidirectional capability is required.

  13. A Permo-Carboniferous tide-storm interactive system: Talchir formation, Raniganj Basin, India

    NASA Astrophysics Data System (ADS)

    Bhattacharya, H. N.; Bhattacharya, Biplab

    2006-08-01

    Sandstone/siltstone-mudstone interbedded facies of the Permo-Carboniferous Talchir formation, Gondwana Supergroup, is exposed in the Raniganj Basin and records the activities of tidal currents in a terminoglacial, storm-influenced shallow marine setting. Tidal bundles of various types with pause plane drapes, evidence of time-velocity asymmetry and rare bidirectional current flow patterns are indicative of tidal activity. Chance preservation of such structures from storm reworking might have occurred due to dampening of storm waves on the low-gradient muddy substrate of the tidal flat. The tide-generated stratifications are draped by over-thickened muddy-siltstone with wavy/hummocky laminations. Increased suspended sediment concentrations following a storm yielded such thick mudstone drapes. Thin beds containing tidal structures indicate poor sediment supply in a blind tidal embayment.

  14. Hydraulic performance improvement of the bidirectional pit pump installation based on CFD

    NASA Astrophysics Data System (ADS)

    Chen, H. X.; Zhou, D. Q.

    2013-12-01

    At present, the efficiency of bidirectional pit pump installation with lift under 2m is still low because of lack of research on it in the past. In the paper, the CFD numerical method and experimental test were applied to study flow characteristic of bidirectional pit pump installation under positive and reverse condition. Through changing airfoil type and position of blade and stay vane, the comprehensive performance of improved model were obtained by calculating many different models. The results showed that when improved model is obtained with type A runner with 4 blades that is 0.7D away from pit exit and unsymmetrical guide vane 0.25dh which away from the impeller outlet, and the flow pattern of the improved solution is steady with high efficiency. Compared with the original scheme, the efficiency of positive and reverse design condition reach to 67.23% and 58.32% respectively, which is increased 6% more than original model on the design condition and 5% on the optimum operating condition, and it achieved the purpose of improvement. According to the runner blade angle of the optimization solution, model synthetic characteristic curve was drawn and internal flow field characteristics was analyzed under optimal positive and reverse conditions. The numerical calculation shows that owing to the lack of stay vane to recycle the energy in outlet runner chamber, the water flow regime is not steady enough in the outlet passage, and that is the main reason for lower efficiency at reverse condition than that at positive condition.

  15. Tourist-Centric Citizen Science in Denali National Park and Preserve

    ERIC Educational Resources Information Center

    Fischer, Heather A.

    2017-01-01

    Citizen Science programs create a bi-directional flow of knowledge between scientists and citizen volunteers; this flow democratizes science in order to create an informed public (Bonney et al. 2014; Brown, Kelly, and Whitall 2014). This democratization is a fundamental part of creating a science that can address today's pressing environmental,…

  16. Bidirectional DC/DC Converter

    NASA Astrophysics Data System (ADS)

    Pedersen, F.

    2008-09-01

    The presented bidirectional DC/DC converter design concept is a further development of an already existing converter used for low battery voltage operation.For low battery voltage operation a high efficient low parts count DC/DC converter was developed, and used in a satellite for the battery charge and battery discharge function.The converter consists in a bidirectional, non regulating DC/DC converter connected to a discharge regulating Buck converter and a charge regulating Buck converter.The Bidirectional non regulating DC/DC converter performs with relatively high efficiency even at relatively high currents, which here means up to 35Amps.This performance was obtained through the use of power MOSFET's with on- resistances of only a few mille Ohms connected to a special transformer allowing paralleling several transistor stages on the low voltage side of the transformer. The design is patent protected. Synchronous rectification leads to high efficiency at the low battery voltages considered, which was in the range 2,7- 4,3 Volt DC.The converter performs with low switching losses as zero voltage zero current switching is implemented in all switching positions of the converter.Now, the drive power needed, to switch a relatively large number of low Ohm , hence high drive capacitance, power MOSFET's using conventional drive techniques would limit the overall conversion efficiency.Therefore a resonant drive consuming considerable less power than a conventional drive circuit was implemented in the converter.To the originally built and patent protected bidirectional non regulating DC/DC converter, is added the functionality of regulation.Hereby the need for additional converter stages in form of a Charge Buck regulator and a Discharge Buck regulator is eliminated.The bidirectional DC/DC converter can be used in connection with batteries, motors, etc, where the bidirectional feature, simple design and high performance may be useful.

  17. Gene Flow within and between Catchments in the Threatened Riparian Plant Myricaria germanica

    PubMed Central

    Werth, Silke; Scheidegger, Christoph

    2014-01-01

    One of the major distinctions of riparian habitats is their linearity. In linear habitats, gene flow is predicted to follow a one-dimensional stepping stone model, characterized by bidirectional gene flow between neighboring populations. Here, we studied the genetic structure of Myricaria germanica, a threatened riparian shrub which is capable of both wind and water dispersal. Our data led us to reject the ‘one catchment – one gene pool’ hypothesis as we found support for two gene pools, rather than four as expected in a study area including four catchments. This result also implies that in the history of the studied populations, dispersal across catchments has occurred. Two contemporary catchment-crossing migration events were detected, albeit between spatially proximate catchments. Allelic richness and inbreeding coefficients differed substantially between gene pools. There was significant isolation by distance, and our data confirmed the one-dimensional stepping-stone model of gene flow. Contemporary migration was bidirectional within the studied catchments, implying that dispersal vectors other than water are important for M. germanica. PMID:24932520

  18. The Association of Investment Model Variables and Dyadic Patterns of Physical Partner Violence: A Study of College Women.

    PubMed

    Dixon, Kristiana J; Edwards, Katie M; Gidycz, Christine A

    2016-10-01

    Previous research has examined the association between intimate partner violence (IPV) victimization experiences and investment model variables, particularly with relation to leaving intentions. However, research only has begun to explore the impact that various dyadic patterns of IPV (i.e., unidirectional victimization, unidirectional perpetration, bidirectional violence, and non-violence) have on investment model variables. Grounded in behavioral principles, the current study used a sample of college women to assess the impact that perpetration and victimization have on investment model variables. Results indicated that 69.2% of the sample was in a relationship with no IPV. Among those who reported IPV in their relationships, 11.9% reported unidirectional perpetration, 10.6% bidirectional violence, and 7.4% unidirectional victimization. Overall, the findings suggest that women's victimization (i.e., victim only and bidirectional IPV) is associated with lower levels of satisfaction and commitment, and that women's perpetration (i.e., perpetration only and bidirectional IPV) is associated with higher levels of investment. Women in bidirectionally violent relationships reported higher quality alternatives than women in non-violent relationships. The current study emphasizes the importance of considering both IPV perpetration and IPV victimization experiences when exploring women's decisions to remain in relationships. © The Author(s) 2015.

  19. Studies of vehicle overtaking dynamics and its influence on traffic flow at a bidirectional road

    NASA Astrophysics Data System (ADS)

    Echab, H.; Marzoug, R.; Lakouari, N.; Ez-Zahraouy, H.

    For the purposes of optimizing traffic flow composed of different types of vehicles, it is important to understand the interactions between them. This paper proposes a cellular automata model to investigate a bidirectional two-lane traffic flow under the periodic boundary condition. The vehicle flux and the phase diagrams of the system in the (ρ1,ρ2) space are constructed by applying two different overtaking models (symmetric, asymmetric). The inter-lane correlation and the overtaking frequency are also studied. The simulation results show that the variation of the density of one lane has an apparent influence on the traffic of the adjacent lane. Furthermore, it is found that the phase diagram on both models is classified into several regions. Thus, for the symmetric model, as the overtaking probability increases, the traffic on the system becomes better. Likewise, the results also indicate that the asymmetric model can effectively enhance the traffic capacity and alleviate the congested state.

  20. The bidirectional associations between state anger and rumination and the role of trait mindfulness.

    PubMed

    Borders, Ashley; Lu, Shou-En

    2017-07-01

    Rumination is associated with exacerbated angry mood. Angry moods may also trigger rumination. However, research has not empirically tested the bidirectional associations of state rumination and anger, as experience sampling methodology can do. We predicted that state anger and rumination would be bi-directionally associated, both concurrently and over time, even controlling for trait anger and rumination. In addition, because mindfulness is associated with rumination and anger at the bivariate level, we examined the effect of trait mindfulness on the bidirectional association between state rumination and anger. We examined two hypotheses: (i) state rumination mediates the effect of trait mindfulness on state anger; and (ii) trait mindfulness weakens, or moderates, the bidirectional associations between state rumination and anger. In an experience-sampling study, 200 college students reported their current ruminative thinking and angry mood several times a day for 7 days. Mixed model analyses indicated that state anger and rumination predicted each other concurrently. In cross-lagged analyses, previous anger did not uniquely predict current rumination; previous rumination predicted current anger, although the effect was small. In support of our hypothesis, state rumination mediated the association between trait mindfulness and state anger. Additionally, trait mindfulness moderated the concurrent and cross-lagged associations between state rumination and anger, although the results were complex. This study contributes new information about the complex interplay of rumination and anger. Findings also add support to the theory that mindfulness decreases emotional reactivity. Aggr. Behav. 43:342-351, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  1. Bidirectional Linkages between Psychological Symptoms and Sexual Activities among African American Adolescent Girls in Psychiatric Care

    ERIC Educational Resources Information Center

    Starr, Lisa R.; Donenberg, Geri R.; Emerson, Erin

    2012-01-01

    The current study examines longitudinal associations between light and heavy sexual experiences and psychiatric symptoms in African American adolescent girls receiving mental health care. Research supports bidirectional associations between adolescent romantic and sexual behaviors and depression and other mental health problems, but this finding…

  2. Initial Studies of the Bidirectional Reflectance Distribution Function of Multi-Walled Carbon Nanotube Structures for Stray Light Control Applications

    NASA Technical Reports Server (NTRS)

    Butler, J. J.; Tveekrem, J. L.; Quijada, M. A.; Getty, S. A.; Hagopian, J. G.; Georglev, G. T.

    2010-01-01

    The presentation examines the application of low reflectance surfaces in optical instruments, multi-walled carbon nanotubes (MWCNTs), research objects, MWCNT samples, measurement of 8 deg. directional/hemispherical reflectance, measurement of bidirectional reflectance distribution function (BRDF), and what is current the "blackest ever black".

  3. Blood Flow Modulation of Vascular Dynamics

    PubMed Central

    Lee, Juhyun; Sevag Packard, René R.; Hsiai, Tzung K.

    2015-01-01

    Purpose of review Blood flow is intimately linked with cardiovascular development, repair, and dysfunction. The current review will build on the fluid mechanical principle underlying hemodynamic shear forces, mechanotransduction, and metabolic effects. Recent findings Pulsatile flow produces both time- (∂τ /∂t)and spatial-varying shear stress (∂τ /∂x) to modulate vascular oxidative stress and inflammatory response with pathophysiological significance to atherosclerosis. The characteristics of hemodynamic shear forces; namely, steady laminar (∂τ /∂t= 0), pulsatile (PSS: unidirectional forward flow), and oscillatory shear stress (OSS: bidirectional with a near net 0 forward flow) modulate mechano-signal transduction to influence metabolic effects on vascular endothelial function. Atheroprotective PSS promotes anti-oxidant, anti-inflammatory, and anti-thrombotic responses, whereas atherogenic OSS induces NADPH oxidase–JNK signaling to increase mitochondrial superoxide production, protein degradation of manganese superoxide dismutase (MnSOD), and post-translational protein modifications of LDL particles in the disturbed flow-exposed regions of vasculature. In the era of tissue regeneration, shear stress has been implicated in re-activation of developmental genes; namely, Wnt and Notch signaling, for vascular development and repair. Summary Blood flow imparts a dynamic continuum from vascular development to repair. Augmentation of PSS confers atheroprotection and re-activation of developmental signaling pathways for regeneration. PMID:26218416

  4. ISEE 3 observations of low-energy proton bidirectional events and their relation to isolated interplanetary magnetic structures

    NASA Technical Reports Server (NTRS)

    Marsden, R. G.; Sanderson, T. R.; Tranquille, C.; Wenzel, K.-P.; Smith, E. J.

    1987-01-01

    The paper represents the results of a comprehensive survey of low-energy proton bidirectional anisotropies and associated transient magnetic structures as observed in the 35-1600 keV energy range on ISEE-3 during the last solar maximum. The majority of observed bidirectional flow (BDF) events (more than 70 percent) are associated with isolated magnetic structures which are postulated to be an interplanetary manifestation of coronal mass ejection (CME) events. The observed BDF events can be qualitatively grouped into five classes depending on the field signature of the related magnetic structure and the association (or lack of association) with an interplanetary shock. Concerning the topology of the CME-related magnetic structures, the observations are interpreted as being consistent with a detached bubble, comprising closed loops or tightly wound helices.

  5. Hydraulic redistribution of soil water by neotropical savanna trees.

    Treesearch

    Fabian G. Scholz; Sandra J. Bucci; Guillermo Goldstein; et al.

    2002-01-01

    The magnitude and direction of water transport by the roots of eight dominant Brazilian savanna (Cerrado) allowed bidirectional measurements of sap flow. The patterns of sap flow observed during the dry season in species with dimorphic roots systems were consistent with the occurrence of hydraulic redistribution of soil water, the movement of water from moist to drier...

  6. Bidirectional converter for high-efficiency fuel cell powertrain

    NASA Astrophysics Data System (ADS)

    Fardoun, Abbas A.; Ismail, Esam H.; Sabzali, Ahmad J.; Al-Saffar, Mustafa A.

    2014-03-01

    In this paper, a new wide conversion ratio step-up and step-down converter is presented. The proposed converter is derived from the conventional Single Ended Primary Inductor Converter (SEPIC) topology and it is integrated with a capacitor-diode voltage multiplier, which offers a simple structure, reduced electromagnetic interference (EMI), and reduced semiconductors' voltage stresses. Other advantages include: continuous input and output current, extended step-up and step-down voltage conversion ratio without extreme low or high duty-cycle, simple control circuitry, and near-zero input and output ripple currents compared to other converter topologies. The low charging/discharging current ripple and wide gain features result in a longer life-span and lower cost of the energy storage battery system. In addition, the "near-zero" ripple capability improves the fuel cell durability. Theoretical analysis results obtained with the proposed structure are compared with other bi-direction converter topologies. Simulation and experimental results are presented to verify the performance of the proposed bi-directional converter.

  7. The association between the pulse pressure gradient at the cranio-cervical junction derived from phase-contrast magnetic resonance imaging and invasively measured pulsatile intracranial pressure in symptomatic patients with Chiari malformation type 1.

    PubMed

    Frič, Radek; Lindstrøm, Erika Kristina; Ringstad, Geir Andre; Mardal, Kent-André; Eide, Per Kristian

    2016-12-01

    In symptomatic Chiari malformation type 1 (CMI), impaired intracranial compliance (ICC) is associated with an increased cranio-spinal pulsatile pressure gradient. Phase-contrast magnetic resonance imaging (MRI) represents a non-invasive modality for the assessment of the pulse pressure gradient at the cranio-cervical junction (CCJ). We wished to explore how the MRI-derived pulse pressure gradient (MRI-dP) compares with invasively measured pulsatile intracranial pressure (ICP) in CMI, and with healthy controls. From phase-contrast MRI of CMI patients and healthy controls, we computed cerebrospinal fluid (CSF) flow velocities and MRI-dP at the CCJ. We assessed bidirectional flow and compared the flow between the anterior and the posterior subarachnoid space at the CCJ. We computed total intracranial volume (ICV), ventricular CSF volume (VV), and posterior cranial fossa volume (PCFV). We analyzed the static and pulsatile ICP scores from overnight monitoring in CMI patients. Five CMI patients and four healthy subjects were included. The CMI group had a significantly larger extent of tonsillar ectopia, smaller PCFV, and a smaller area of CSF in the FM. The pulsatile ICP (mean ICP wave amplitude, MWA) was abnormally increased in 4/5 CMI patients and correlated positively with MRI-dP. However, the MRI-dP as well as the CSF flow velocities did not differ significantly between CMI and healthy subjects. Moreover, bidirectional flow was observed in both CMI as well as healthy subjects, with no significant difference. In symptomatic CMI patients, we found a significant association between the pulse pressure gradient at the CCJ derived from phase-contrast MRI and the pulsatile ICP (MWA) measured invasively. However, the MRI-dP was close to identical in CMI patients and healthy subjects. Moreover, the CSF flow velocities at the CCJ and the occurrence of bidirectional flow were not different in CMI patients and healthy individuals. Further studies are required to determine the diagnostic role of phase-contrast MRI in CMI patients.

  8. Analytical Methods for Interconnection | Distributed Generation

    Science.gov Websites

    ; ANALYSIS Program Lead Kristen.Ardani@nrel.gov 303-384-4641 Accurately and quickly defining the effects of designed to accommodate voltage rises, bi-directional power flows, and other effects caused by distributed

  9. Novel bidirectional DC-DC converters based on the three-state switching cell

    NASA Astrophysics Data System (ADS)

    da Silva Júnior, José Carlos; Robles Balestero, Juan Paulo; Lessa Tofoli, Fernando

    2016-05-01

    It is well known that there is an increasing demand for bidirectional DC-DC converters for applications that range from renewable energy sources to electric vehicles. Within this context, this work proposes novel DC-DC converter topologies that use the three-state switching cell (3SSC), whose well-known advantages over conventional existing structures are ability to operate at high current levels, while current sharing is maintained by a high frequency transformer; reduction of cost and dimensions of magnetics; improved distribution of losses, with consequent increase of global efficiency and reduction of cost associated to the need of semiconductors with lower current ratings. Three distinct topologies can be derived from the 3SSC: one DC-DC converter with reversible current characteristic able to operate in the first and second quadrants; one DC-DC converter with reversible voltage characteristic able to operate in the first and third quadrants and one DC-DC converter with reversible current and voltage characteristics able to operate in four quadrants. Only the topology with bidirectional current characteristic is analysed in detail in terms of the operating stages in both nonoverlapping and overlapping modes, while the design procedure of the power stage elements is obtained. In order to validate the theoretical assumptions, an experimental prototype is also implemented, so that relevant issues can be properly discussed.

  10. Load calculation on the nozzle in a flue gas desulphurization system

    NASA Astrophysics Data System (ADS)

    Róbert, Olšiak; Zoltán, Fuszko; Zoltán, Csuka

    2017-09-01

    The desulphurization system is used to remove sulfur oxides from exhaust, so-called flue gases through absorbing them via the sprayed suspension. The suspension delivered from the pump system to the atmospheric bi-directional double hollow cone nozzle has the prescribed working pressure. The unknown mechanical load on the solid body of the nozzle is present through the change of moment due to the flow of the suspension through the bi-directional outflow areas [1], [4]. The calculation of the acting forces and torques in the 3 directions was carried out with the methods of computational fluid dynamics (CFD) in the software ANSYS Fluent. The geometric model of the flow areas of the nozzle were created with the methods of reverse engineering. The computational mesh required by the CFD solver was created, and its quality verified with the standard criteria. The used boundary conditions were defined by the hydraulic parameters of the pump system, the properties of the suspension present in the hydraulic system were specified by sample analysis. The post-processed and analyzed results of the CFD calculation, the pressure-field and the velocity magnitudes in particular directions were further used as input parameters at the mechanical analysis of the load on the bi-directional nozzle.

  11. SDN-controlled topology-reconfigurable optical mobile fronthaul architecture for bidirectional CoMP and low latency inter-cell D2D in the 5G mobile era.

    PubMed

    Cvijetic, Neda; Tanaka, Akihiro; Kanonakis, Konstantinos; Wang, Ting

    2014-08-25

    We demonstrate the first SDN-controlled optical topology-reconfigurable mobile fronthaul (MFH) architecture for bidirectional coordinated multipoint (CoMP) and low latency inter-cell device-to-device (D2D) connectivity in the 5G mobile networking era. SDN-based OpenFlow control is used to dynamically instantiate the CoMP and inter-cell D2D features as match/action combinations in control plane flow tables of software-defined optical and electrical switching elements. Dynamic re-configurability is thereby introduced into the optical MFH topology, while maintaining back-compatibility with legacy fiber deployments. 10 Gb/s peak rates with <7 μs back-to-back transmission latency and 29.6 dB total power budget are experimentally demonstrated, confirming the attractiveness of the new approach for optical MFH of future 5G mobile systems.

  12. Excellent selector performance in engineered Ag/ZrO2:Ag/Pt structure for high-density bipolar RRAM applications

    NASA Astrophysics Data System (ADS)

    Wang, Chao; Song, Bing; Zeng, Zhongming

    2017-12-01

    A high-performance selector with bidirectional threshold switching (TS) characteristics of Ag/ZrO2/Pt structure was prepared by incorporating metallic Ag into the ZrO2 matrix. The bidirectional TS device exhibited excellent switching uniformity, forming-free behavior, ultra-low off current of <1 nA and adjustable selectivity (from 102 to 107). The experiment results confirmed that metallic Ag clusters were penetrated into the ZrO2 matrix during the annealing process, which would function as an effective active source responsible for the bidirectional TS. The volatile behavior could be explained by the self-dissolution of unstable filaments caused by minimization of the interfacial energy and thermal effect. Furthermore, a bipolar-type one selector-one resistor (1S-1R) memory device was successfully fabricated and exhibited significant suppression of the undesired sneak current, indicating the great potential as selector in a cross-point array.

  13. Coexistence of ΘI I-loop-current order with checkerboard d -wave CDW/PDW order in a hot-spot model for cuprate superconductors

    NASA Astrophysics Data System (ADS)

    de Carvalho, Vanuildo S.; Pépin, Catherine; Freire, Hermann

    2016-03-01

    We investigate the strong influence of the ΘI I-loop-current order on both unidirectional and bidirectional d -wave charge-density-wave/pair-density-wave (CDW/PDW) composite orders along axial momenta (±Q0,0 ) and (0 ,±Q0) that emerge in an effective hot-spot model departing from the three-band Emery model relevant to the phenomenology of the cuprate superconductors. This study is motivated by the compelling evidence that the ΘI I-loop-current order described by this model may explain groundbreaking experiments such as spin-polarized neutron scattering performed in these materials. Here, we demonstrate, within a saddle-point approximation, that the ΘI I-loop-current order clearly coexists with bidirectional (i.e., checkerboard) d -wave CDW and PDW orders along axial momenta, but is visibly detrimental to the unidirectional (i.e., stripe) case. This result has potentially far-reaching implications for the physics of the cuprates and agrees well with very recent x-ray experiments on YBCO that indicate that at higher dopings the CDW order has indeed a tendency to be bidirectional.

  14. Push-pull switching power amplifier

    NASA Technical Reports Server (NTRS)

    Cuk, Slobodan M. (Inventor)

    1980-01-01

    A true push-pull switching power amplifier is disclosed utilizing two dc-to-dc converters. Each converter is comprised of two inductances, one inductance in series with a DC source and the other inductor in series with the output load, and an electrical energy transferring device with storage capability, namely storage capacitance, with suitable switching means between the inductances to obtain DC level conversion, where the switching means allows bidirectional current (and power) flow, and the switching means of one dc-to-dc converter is driven by the complement of a square-wave switching signal for the other dc-to-dc converter for true push-pull operation. For reduction of current ripple, the inductances in each of the two converters may be coupled, and with proper design of the coupling, the ripple can be reduced to zero at either the input or the output, but preferably the output.

  15. Middle Miocene reworked turbidites in the Baiyun Sag of the Pearl River Mouth Basin, northern South China Sea margin: Processes, genesis, and implications

    NASA Astrophysics Data System (ADS)

    Gong, Chenglin; Wang, Yingmin; Zheng, Rongcai; Hernández-Molina, F. Javier; Li, Yun; Stow, Dorrik; Xu, Qiang; Brackenridge, Rachel E.

    2016-10-01

    Our understanding of reworked turbidites is still in its infancy, and their flow processes and genesis still remain understudied. Core data from the middle Miocene Zhujiang Formation in the Pearl River Mouth Basin allow us to differentiate reworked turbidites, yielding two main contributions. Firstly, reworked turbidites are distinguished from turbidites by the association of traction structures and tidal signatures, which occur in discrete units rather than forming a classic ;Bouma Sequence; for turbidites. Sedimentological characteristics of reworked turbidites proposed here will help to obtain a robust set of diagnostic criteria for the recognition of deep-water non-turbidite deepwater units as reservoirs. Secondly, our results suggest that, in the down-slope direction, classic detritus carried in turbidity flows would synchronously be bidirectionally reworked by internal tides and waves, resulting in tidal signatures seen in the interpreted reworked turbidites. In the along-slope direction, upper parts of dilute turbidity currents would mix vertically with seawater, and muddy fines would be winnowed away by contour currents, whereas lower parts of dilute turbidity currents would probably drop their coarse particles, resulting in traction structures recognized in the documented reworked turbidites. Our work highlights the influence of bottom currents on the development and modification of turbidites and suggests that reworked turbidites were created by the combined action of down-slope transport and reworking and along-slope winnowing and sorting, helping to better understand flow processes and genesis of non-turbidite reservoirs with a great economic interest.

  16. A laser interferometer for measuring skin friction in three-dimensional flows

    NASA Technical Reports Server (NTRS)

    Monson, D. J.

    1983-01-01

    A new, nonintrusive method is described for measuring skin friction in three-dimensional flows with unknown direction. The method uses a laser interferometer to measure the changing slope of a thin oil film applied to a surface experiencing shear stress. The details of the method are described, and skin friction measurements taken in a swirling three-dimensional boundary-layer flow are presented. Comparisons between analytical results and experimental values from the laser interferometer method and from a bidirectional surface-fence gauge are made.

  17. Outpatient blood pressure monitoring using bi-directional text messaging.

    PubMed

    Anthony, Chris A; Polgreen, Linnea A; Chounramany, James; Foster, Eric D; Goerdt, Christopher J; Miller, Michelle L; Suneja, Manish; Segre, Alberto M; Carter, Barry L; Polgreen, Philip M

    2015-05-01

    To diagnose hypertension, multiple blood pressure (BP) measurements are recommended. We randomized patients into three groups: EMR-only (patients recorded BP measurements in an electronic medical record [EMR] web portal), EMR + reminders (patients were sent text message reminders to record their BP measurements in the EMR), and bi-directional text messaging (patients were sent a text message asking them to respond with their current BP). Subjects were asked to complete 14 measurements. Automated messages were sent to each patient in the bi-directional text messaging and EMR + reminder groups twice daily. Among 121 patients, those in the bi-directional text messaging group reported the full 14 measurements more often than both the EMR-only group (P < .001) and the EMR + reminders group (P = .038). Also, the EMR + reminders group outperformed the EMR-only group (P < .001). Bi-directional automated text messaging is an effective way to gather patient BP data. Text-message-based reminders alone are an effective way to encourage patients to record BP measurements. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  18. Strategies for impediment rehabilitation to create fish passage opportunities in the Rappahannock River basin.

    DOT National Transportation Integrated Search

    2004-01-01

    Areas where anthropogenic development coincides with aquatic systems often impede the flow of organisms and nutrients in either an upstream, downstream, or bidirectional path. These impediments are especially outstanding in the tidal and nontidal fre...

  19. Integrated capabilities in heavy vehicles : human factors research needs

    DOT National Transportation Integrated Search

    2003-10-09

    The Full Road Closure method uses facility closure and total traffic diversion, which may be for one direction or bi-directional traffic flow, to accelerate construction and reduce the negative impacts of work zones. With good planning, interagency c...

  20. Channel water balance and exchange with subsurface flow along a mountain headwater stream in Montana, United States

    USGS Publications Warehouse

    Payn, R.A.; Gooseff, M.N.; McGlynn, B.L.; Bencala, K.E.; Wondzell, S.M.

    2009-01-01

    Channel water balances of contiguous reaches along streams represent a poorly understood scale of stream-subsurface interaction. We measured reach water balances along a headwater stream in Montana, United States, during summer base flow recessions. Reach water balances were estimated from series of tracer tests in 13 consecutive reaches delineated evenly along a 2.6 km valley segment. For each reach, we estimated net change in discharge, gross hydrologic loss, and gross hydrologic gain from tracer dilution and mass recovery. Four series of tracer tests were performed during relatively high, intermediate, and low base flow conditions. The relative distribution of channel water along the stream was strongly related to a transition in valley structure, with a general increase in gross losses through the recession. During tracer tests at intermediate and low flows, there were frequent substantial losses of tracer mass (>10%) that could not be explained by net loss in flow over the reach, indicating that many of the study reaches were concurrently losing and gaining water. For example, one reach with little net change in discharge exchanged nearly 20% of upstream flow with gains and losses along the reach. These substantial bidirectional exchanges suggest that some channel interactions with subsurface flow paths were not measurable by net change in flow or transient storage of recovered tracer. Understanding bidirectional channel water balances in stream reaches along valleys is critical to an accurate assessment of stream solute fate and transport and to a full assessment of exchanges between the stream channel and surrounding subsurface.

  1. Channel water balance and exchange with subsurface flow along a mountain headwater stream in Montana, United States

    USGS Publications Warehouse

    Payn, R.A.; Gooseff, M.N.; McGlynn, B.L.; Bencala, K.E.; Wondzell, S.M.

    2009-01-01

    Channel water balances of contiguous reaches along streams represent a poorly understood scale of stream-subsurface interaction. We measured reach water balances along a headwater stream in Montana, United States, during summer base flow recessions. Reach water balances were estimated from series of tracer tests in 13 consecutive reaches delineated evenly along a 2.6 km valley segment. For each reach, we estimated net change in discharge, gross hydrologic loss, and gross hydrologic gain from tracer dilution and mass recovery. Four series of tracer tests were performed during relatively high, intermediate, and low base flow conditions. The relative distribution of channel water along the stream was strongly related to a transition in valley structure, with a general increase in gross losses through the recession. During tracer tests at intermediate and low flows, there were frequent substantial losses of tracer mass (>10%) that could not be explained by net loss in flow over the reach, indicating that many of the study reaches were concurrently losing and gaining water. For example, one reach with little net change in discharge exchanged nearly 20% of upstream flow with gains and losses along the reach. These substantial bidirectional exchanges suggest that some channel interactions with subsurface flow paths were not measurable by net change in flow or transient storage of recovered tracer. Understanding bidirectional channel water balances in stream reaches along valleys is critical to an accurate assessment of stream solute fate and transport and to a full assessment of exchanges between the stream channel and surrounding subsurface. Copyright 2009 by the American Geophysical Union.

  2. Decoding of grasping information from neural signals recorded using peripheral intrafascicular interfaces.

    PubMed

    Micera, Silvestro; Rossini, Paolo M; Rigosa, Jacopo; Citi, Luca; Carpaneto, Jacopo; Raspopovic, Stanisa; Tombini, Mario; Cipriani, Christian; Assenza, Giovanni; Carrozza, Maria C; Hoffmann, Klaus-Peter; Yoshida, Ken; Navarro, Xavier; Dario, Paolo

    2011-09-05

    The restoration of complex hand functions by creating a novel bidirectional link between the nervous system and a dexterous hand prosthesis is currently pursued by several research groups. This connection must be fast, intuitive, with a high success rate and quite natural to allow an effective bidirectional flow of information between the user's nervous system and the smart artificial device. This goal can be achieved with several approaches and among them, the use of implantable interfaces connected with the peripheral nervous system, namely intrafascicular electrodes, is considered particularly interesting. Thin-film longitudinal intra-fascicular electrodes were implanted in the median and ulnar nerves of an amputee's stump during a four-week trial. The possibility of decoding motor commands suitable to control a dexterous hand prosthesis was investigated for the first time in this research field by implementing a spike sorting and classification algorithm. The results showed that motor information (e.g., grip types and single finger movements) could be extracted with classification accuracy around 85% (for three classes plus rest) and that the user could improve his ability to govern motor commands over time as shown by the improved discrimination ability of our classification algorithm. These results open up new and promising possibilities for the development of a neuro-controlled hand prosthesis.

  3. Variational optical flow computation in real time.

    PubMed

    Bruhn, Andrés; Weickert, Joachim; Feddern, Christian; Kohlberger, Timo; Schnörr, Christoph

    2005-05-01

    This paper investigates the usefulness of bidirectional multigrid methods for variational optical flow computations. Although these numerical schemes are among the fastest methods for solving equation systems, they are rarely applied in the field of computer vision. We demonstrate how to employ those numerical methods for the treatment of variational optical flow formulations and show that the efficiency of this approach even allows for real-time performance on standard PCs. As a representative for variational optic flow methods, we consider the recently introduced combined local-global method. It can be considered as a noise-robust generalization of the Horn and Schunck technique. We present a decoupled, as well as a coupled, version of the classical Gauss-Seidel solver, and we develop several multgrid implementations based on a discretization coarse grid approximation. In contrast, with standard bidirectional multigrid algorithms, we take advantage of intergrid transfer operators that allow for nondyadic grid hierarchies. As a consequence, no restrictions concerning the image size or the number of traversed levels have to be imposed. In the experimental section, we juxtapose the developed multigrid schemes and demonstrate their superior performance when compared to unidirectional multgrid methods and nonhierachical solvers. For the well-known 316 x 252 Yosemite sequence, we succeeded in computing the complete set of dense flow fields in three quarters of a second on a 3.06-GHz Pentium4 PC. This corresponds to a frame rate of 18 flow fields per second which outperforms the widely-used Gauss-Seidel method by almost three orders of magnitude.

  4. A simple, dynamic, hydrological model of a mesotidal salt marsh

    EPA Science Inventory

    Salt marsh hydrology presents many difficulties from a modeling standpoint: the bi-directional flows of tidal waters, variable water densities due to mixing of fresh and salt water, significant influences from vegetation, and complex stream morphologies. Because of these difficu...

  5. Measurement of bi-directional ion acceleration along a convergent-divergent magnetic nozzle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Yunchao, E-mail: yunchao.zhang@anu.edu.au; Charles, Christine; Boswell, Rod

    Bi-directional plasma expansion resulting in the formation of ion beams travelling in opposite directions is respectively measured in the converging and diverging parts of a magnetic nozzle created using a low-pressure helicon radio-frequency plasma source. The axial profile of ion saturation current along the nozzle is closely correlated to that of the magnetic flux density, and the ion “swarm” has a zero convective velocity at the magnetic throat where plasma generation is localized, thereby balancing the bi-directional particle loss. The ion beam potentials measured on both sides of the magnetic nozzle show results consistent with the maximum plasma potential measuredmore » at the throat.« less

  6. The assisted bidirectional Glenn: a novel surgical approach for first-stage single-ventricle heart palliation.

    PubMed

    Esmaily-Moghadam, Mahdi; Hsia, Tain-Yen; Marsden, Alison L

    2015-03-01

    Outcomes after a modified Blalock-Taussig shunt (mBTS) in neonates with single-ventricle physiology remain unsatisfactory. However, initial palliation with a superior cavopulmonary connection, such as a bidirectional Glenn (BDG), is discouraged, owing to potential for inadequate pulmonary blood flow (PBF). We tested the feasibility of a novel surgical approach, adopting the engineering concept of an ejector pump, whereby the flow in the BDG is "assisted" by injection of a high-energy flow stream from the systemic circulation. Realistic 3-dimensional models of the neonatal mBTS and BDG circulations were created. The "assisted" bidirectional Glenn (ABG) consisted of a shunt between the right innominate artery and the superior vena cava (SVC), with a 1.5-mm clip near the SVC anastomosis to create a Venturi effect. The 3 models were coupled to a validated hydraulic circulation model, and 2 pulmonary vascular resistance (PVR) values (7 and 2.3 Wood units) were simulated. The ABG provided the highest systemic oxygen saturation and oxygen delivery at both PVR levels. In addition to achieving higher PBF than the BDG, the ABG produced a lower single-ventricular workload than mBTS. SVC pressure was highest in the ABG model (ABG: 15; Glenn: 11; mBTS: 3 mm Hg; PVR = 7 Wood units), but at low PVR, the SVC pressure was significantly lower (ABG: 8; Glenn: 6; mBTS: <3 mm Hg). Adopting the principle of an ejector pump, with additional flow directed into the SVC in a BDG, the ABG appears to increase PBF with a modest increase in SVC and pulmonary arterial pressure. Although multiscale modeling results demonstrate the conceptual feasibility of the ABG circulation, further technical refinement and investigations are necessary, especially in an appropriate animal model. Copyright © 2015 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  7. Creating fast flow channels in paper fluidic devices to control timing of sequential reactions.

    PubMed

    Jahanshahi-Anbuhi, Sana; Chavan, Puneet; Sicard, Clémence; Leung, Vincent; Hossain, S M Zakir; Pelton, Robert; Brennan, John D; Filipe, Carlos D M

    2012-12-07

    This paper reports the development of a method to control the flow rate of fluids within paper-based microfluidic analytical devices. We demonstrate that by simply sandwiching paper channels between two flexible films, it is possible to accelerate the flow of water through paper by over 10-fold. The dynamics of this process are such that the height of the liquid is dependent on time to the power of 1/3. This dependence was validated using three different flexible films (with markedly different contact angles) and three different fluids (water and two silicon oils with different viscosities). These covered channels provide a low-cost method for controlling the flow rate of fluid in paper channels, and can be added following printing of reagents to control fluid flow in selected fluidic channels. Using this method, we redesigned a previously published bidirectional lateral flow pesticide sensor to allow more rapid detection of pesticides while eliminating the need to run the assay in two stages. The sensor is fabricated with sol-gel entrapped reagents (indoxyl acetate in a substrate zone and acetylcholinesterase, AChE, in a sensing zone) present in an uncovered "slow" flow channel, with a second, covered "fast" channel used to transport pesticide samples to the sensing region through a simple paper-flap valve. In this manner, pesticides reach the sensing region first to allow preincubation, followed by delivery of the substrate to generate a colorimetric signal. This format results in a uni-directional device that detects the presence of pesticides two times faster than the original bidirectional sensors.

  8. Study of switching transients in high frequency converters

    NASA Technical Reports Server (NTRS)

    Zinger, Donald S.; Elbuluk, Malik E.; Lee, Tony

    1993-01-01

    As the semiconductor technologies progress rapidly, the power densities and switching frequencies of many power devices are improved. With the existing technology, high frequency power systems become possible. Use of such a system is advantageous in many aspects. A high frequency ac source is used as the direct input to an ac/ac pulse-density-modulation (PDM) converter. This converter is a new concept which employs zero voltage switching techniques. However, the development of this converter is still in its infancy stage. There are problems associated with this converter such as a high on-voltage drop, switching transients, and zero-crossing detecting. Considering these problems, the switching speed and power handling capabilities of the MOS-Controlled Thyristor (MCT) makes the device the most promising candidate for this application. A complete insight of component considerations for building an ac/ac PDM converter for a high frequency power system is addressed. A power device review is first presented. The ac/ac PDM converter requires switches that can conduct bi-directional current and block bi-directional voltage. These bi-directional switches can be constructed using existing power devices. Different bi-directional switches for the converter are investigated. Detailed experimental studies of the characteristics of the MCT under hard switching and zero-voltage switching are also presented. One disadvantage of an ac/ac converter is that turn-on and turn-off of the switches has to be completed instantaneously when the ac source is at zero voltage. Otherwise shoot-through current or voltage spikes can occur which can be hazardous to the devices. In order for the devices to switch softly in the safe operating area even under non-ideal cases, a unique snubber circuit is used in each bi-directional switch. Detailed theory and experimental results for circuits using these snubbers are presented. A current regulated ac/ac PDM converter built using MCT's and IGBT's is evaluated.

  9. Electroosmotic pumps for microflow analysis

    PubMed Central

    Wang, Xiayan; Wang, Shili; Gendhar, Brina; Cheng, Chang; Byun, Chang Kyu; Li, Guanbin; Zhao, Meiping; Liu, Shaorong

    2009-01-01

    With rapid development in microflow analysis, electroosmotic pumps are receiving increasing attention. Compared to other micropumps, electroosmotic pumps have several unique features. For example, they are bi-directional, can generate constant and pulse-free flows with flow rates well suited to microanalytical systems, and can be readily integrated with lab-on-chip devices. The magnitude and the direction of flow of an electroosmotic pump can be changed instantly. In addition, electroosmotic pumps have no moving parts. In this article, we discuss common features, introduce fabrication technologies and highlight applications of electroosmotic pumps. PMID:20047021

  10. Bidirectional Relations between Parenting Practices and Child Externalizing Behavior: A Cross-Lagged Panel Analysis in the Context of a Psychosocial Treatment and 3-Year Follow-up

    ERIC Educational Resources Information Center

    Shaffer, Anne; Lindhiem, Oliver; Kolko, David J.; Trentacosta, Christopher J.

    2013-01-01

    In the current study, we examined longitudinal changes in, and bidirectional effects between, parenting practices and child behavior problems in the context of a psychosocial treatment and 3-year follow-up period. The sample comprised 139 parent-child dyads (child ages 6-11) who participated in a modular treatment protocol for early-onset ODD or…

  11. Dove prism based rotating dual beam bidirectional Doppler OCT

    PubMed Central

    Blatter, Cedric; Coquoz, Séverine; Grajciar, Branislav; Singh, Amardeep S. G.; Bonesi, Marco; Werkmeister, René M.; Schmetterer, Leopold; Leitgeb, Rainer A.

    2013-01-01

    Traditional Doppler OCT is highly sensitive to motion artifacts due to the dependence on the Doppler angle. This limits its accuracy in clinical practice. To overcome this limitation, we use a bidirectional dual beam technique equipped with a novel rotating scanning scheme employing a Dove prism. The volume is probed from two distinct illumination directions with variable controlled incidence plane, allowing for reconstruction of the true flow velocity at arbitrary vessel orientations. The principle is implemented with Swept Source OCT at 1060nm with 100,000 A-Scans/s. We apply the system to resolve pulsatile retinal absolute blood velocity by performing segment scans around the optic nerve head and circumpapillary scan time series. PMID:23847742

  12. Bi-directional, buried-wire skin-friction gage

    NASA Technical Reports Server (NTRS)

    Higuchi, H.; Peake, D. J.

    1978-01-01

    A compact, nonobtrusive, bi-directional, skin-friction gage was developed to measure the mean shear stress beneath a three-dimensional boundary layer. The gage works by measuring the heat flux from two orthogonal wires embedded in the surface. Such a gage was constructed and its characteristics were determined for different angles of yaw in a calibration experiment in subsonic flow with a Preston tube used as a standard. Sample gages were then used in a fully three-dimensional turbulent boundary layer on a circular cone at high relative incidence, where there were regimes of favorable and adverse pressure gradients and three-dimensional separation. Both the direction and magnitude of skin friction were then obtained on the cone surface.

  13. Design and Development of Sequential Rotary Valve

    NASA Technical Reports Server (NTRS)

    D’Orsi, Nicholas; Castillo, Priscilla

    2017-01-01

    Valves are used to regulate the flow of fluids through systems. This rotary valve's main purpose is to fill, pressurize, empty, and vent three smaller tanks with the supply of one larger tank. Many different designs are being taken into consideration, which are each at different stages of development. The furthest along uses three ball valves on a common shaft to open and close their respective ports as the shaft completes one full rotation or cycle. We were tasked with advancing this design to its first test as a plastic model for flow verification, as well as sizing and ordering the necessary O-rings and fasteners. A motor will also be sized to satisfy the torque requirements, and will then be programmed using a Raspberry Pi to rotate the shaft at the calculated speed and dwelling times needed to fill each tank equally. In addition, we have also been advancing designs that use a camshaft and poppets. These are earlier on in their development, currently being sized to replicate the expected flow patterns of the rotary ball valve. Expected outcomes of this valve include bi-directionality, successful sealing under pressure, and accurate cycling.

  14. Materials and technologies for soft implantable neuroprostheses

    NASA Astrophysics Data System (ADS)

    Lacour, Stéphanie P.; Courtine, Grégoire; Guck, Jochen

    2016-10-01

    Implantable neuroprostheses are engineered systems designed to restore or substitute function for individuals with neurological deficits or disabilities. These systems involve at least one uni- or bidirectional interface between a living neural tissue and a synthetic structure, through which information in the form of electrons, ions or photons flows. Despite a few notable exceptions, the clinical dissemination of implantable neuroprostheses remains limited, because many implants display inconsistent long-term stability and performance, and are ultimately rejected by the body. Intensive research is currently being conducted to untangle the complex interplay of failure mechanisms. In this Review, we emphasize the importance of minimizing the physical and mechanical mismatch between neural tissues and implantable interfaces. We explore possible materials solutions to design and manufacture neurointegrated prostheses, and outline their immense therapeutic potential.

  15. Analysis of serial coronary artery flow patterns early after primary angioplasty: new insights into the dynamics of the microcirculation.

    PubMed

    Sharif, Dawod; Rofe, Guy; Sharif-Rasslan, Amal; Goldhammer, Ehud; Makhoul, Nabeel; Shefer, Arie; Hassan, Amin; Rauchfleisch, Shmuel; Rosenschein, Uri

    2008-06-01

    The temporal behavior of the coronary microcirculation in acute myocardial infarction may affect outcome. Diastolic deceleration time and early systolic flow reversal derived from coronary artery blood flow velocity patterns reflect microcirculatory function. To assess left anterior descending coronary artery flow velocity patterns using Doppler transthoracic echocardiography after primary percutaneous coronary intervention, in patients with anterior AMI. Patterns of flow velocity patterns of the LAD were obtained using transthoracic echocardiography-Doppler in 31 consecutive patients who presented with anterior AMI. Measurements were done at 6 hours, 36-48 hours, and 5 days after successful PPCI. Measurements of DDT and pressure half times (Pt%), as well as observation for ESFR were performed. In the first 2 days following PPCI, the average DDT (600 +/- 340 msec) was shorter than on day 5 (807 +/- 332 msec) (P < 0.012), FVP in the first 2 days were dynamic and bidirectional: from short DDT (< 600 msec) to long DDT (> 600 msec) and vice versa. On day 5 most DDTs became longer. Pt1/2 at 6 hours was not different than at day 2 (174 +/- 96 vs. 193 +/- 99 msec, P = NS) and became longer on day 5 (235 +/- 98 msec, P = 0.012). Bidirectional patterns were also observed in the ESFR in 6 patients (19%) at baseline, in 4 (13%) at 36 hours, and in 2 (6.5%) on day 5 after PPCI. Flow velocity patterns of the LAD after PPCI in AMI are dynamic and reflect unpredictable changes in microcirculation.

  16. Changes in Optical Properties of Spacecraft Materials Due to Combined Effects of Aging Factors in a Space Environment

    DTIC Science & Technology

    2013-07-01

    display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 16-07-2013 2...Bidirectional scattering distribution function (BSDF) and Bidirectional reflectance distribution function ( BRDF ) measurements were conducted for the...radiation (visible, ultraviolet, vacuum ultraviolet and soft X-ray radiation) at an altitude of 400 km 4) BSDF/ BRDF measurements have been conducted for

  17. A Bidirectional Neural Interface IC with Chopper Stabilized BioADC Array and Charge Balanced Stimulator

    PubMed Central

    Greenwald, Elliot; So, Ernest; Wang, Qihong; Mollazadeh, Mohsen; Maier, Christoph; Etienne-Cummings, Ralph; Cauwenberghs, Gert; Thakor, Nitish

    2016-01-01

    We present a bidirectional neural interface with a 4-channel biopotential analog-to-digital converter (bioADC) and a 4-channel current-mode stimulator in 180nm CMOS. The bioADC directly transduces microvolt biopotentials into a digital representation without a voltage-amplification stage. Each bioADC channel comprises a continuous-time first-order ΔΣ modulator with a chopper-stabilized OTA input and current feedback, followed by a second-order comb-filter decimator with programmable oversampling ratio. Each stimulator channel contains two independent digital-to-analog converters for anodic and cathodic current generation. A shared calibration circuit matches the amplitude of the anodic and cathodic currents for charge balancing. Powered from a 1.5V supply, the analog and digital circuits in each recording channel draw on average 1.54 μA and 2.13 μA of supply current, respectively. The bioADCs achieve an SNR of 58 dB and a SFDR of >70 dB, for better than 9-b ENOB. Intracranial EEG recordings from an anesthetized rat are shown and compared to simultaneous recordings from a commercial reference system to validate performance in-vivo. Additionally, we demonstrate bidirectional operation by recording cardiac modulation induced through vagus nerve stimulation, and closed-loop control of cardiac rhythm. The micropower operation, direct digital readout, and integration of electrical stimulation circuits make this interface ideally suited for closed-loop neuromodulation applications. PMID:27845676

  18. Bidirectional private key exchange using delay-coupled semiconductor lasers.

    PubMed

    Porte, Xavier; Soriano, Miguel C; Brunner, Daniel; Fischer, Ingo

    2016-06-15

    We experimentally demonstrate a key exchange cryptosystem based on the phenomenon of identical chaos synchronization. In our protocol, the private key is symmetrically generated by the two communicating partners. It is built up from the synchronized bits occurring between two current-modulated bidirectionally coupled semiconductor lasers with additional self-feedback. We analyze the security of the exchanged key and discuss the amplification of its privacy. We demonstrate private key generation rates up to 11  Mbit/s over a public channel.

  19. Video Super-Resolution via Bidirectional Recurrent Convolutional Networks.

    PubMed

    Huang, Yan; Wang, Wei; Wang, Liang

    2018-04-01

    Super resolving a low-resolution video, namely video super-resolution (SR), is usually handled by either single-image SR or multi-frame SR. Single-Image SR deals with each video frame independently, and ignores intrinsic temporal dependency of video frames which actually plays a very important role in video SR. Multi-Frame SR generally extracts motion information, e.g., optical flow, to model the temporal dependency, but often shows high computational cost. Considering that recurrent neural networks (RNNs) can model long-term temporal dependency of video sequences well, we propose a fully convolutional RNN named bidirectional recurrent convolutional network for efficient multi-frame SR. Different from vanilla RNNs, 1) the commonly-used full feedforward and recurrent connections are replaced with weight-sharing convolutional connections. So they can greatly reduce the large number of network parameters and well model the temporal dependency in a finer level, i.e., patch-based rather than frame-based, and 2) connections from input layers at previous timesteps to the current hidden layer are added by 3D feedforward convolutions, which aim to capture discriminate spatio-temporal patterns for short-term fast-varying motions in local adjacent frames. Due to the cheap convolutional operations, our model has a low computational complexity and runs orders of magnitude faster than other multi-frame SR methods. With the powerful temporal dependency modeling, our model can super resolve videos with complex motions and achieve well performance.

  20. Experimental prototype of an electric elevator

    NASA Astrophysics Data System (ADS)

    Gaiceanu, M.; Epure, S.; Ciuta, S.

    2016-08-01

    The main objective is to achieve an elevator prototype powered by a three-phase voltage system via a bidirectional static power converter ac-ac with regenerating capability. In order to diminish the power size of the electric motor up to 1/3 of rated power, the elevator contains two carriages of the same weight, one serving as the payload, and the other as counterweight. Before proper operation of the static power converter, the capacitor must be charged at rated voltage via a precharge circuit. At the moment of stabilizing the DC voltage at nominal value, the AC-AC power converter can operates in the proper limits. The functions of the control structure are: the load control task, speed and torque controls. System includes transducers for current measuring, voltage sensors and encoder. As reserve power sources the hybrid battery-photovoltaic panels are used. The control voltage is modulated by implementing four types of pulse width modulations: sinusoidal, with reduced commutation, third order harmonic insertion, and the space vector modulation. Therefore, the prototype could operates with an increased efficiency, in spite of the existing ones. The experimental results confirm the well design of the chosen solution. The control solution assures bidirectional power flow control, precharge control, and load control and it is implemented on a digital signal processor. The elevator capacity is between 300-450 kg, and it is driven by using a 1.5 kW three-phase asynchronous machine.

  1. Study on bi-directional pedestrian movement using ant algorithms

    NASA Astrophysics Data System (ADS)

    Sibel, Gokce; Ozhan, Kayacan

    2016-01-01

    A cellular automata model is proposed to simulate bi-directional pedestrian flow. Pedestrian movement is investigated by using ant algorithms. Ants communicate with each other by dropping a chemical, called a pheromone, on the substrate while crawling forward. Similarly, it is considered that oppositely moving pedestrians drop ‘visual pheromones’ on their way and the visual pheromones might cause attractive or repulsive interactions. This pheromenon is introduced into modelling the pedestrians’ walking preference. In this way, the decision-making process of pedestrians will be based on ‘the instinct of following’. At some densities, the relationships of velocity-density and flux-density are analyzed for different evaporation rates of visual pheromones. Lane formation and phase transition are observed for certain evaporation rates of visual pheromones.

  2. Bi-directional magnetic domain wall shift register

    NASA Astrophysics Data System (ADS)

    Read, D. E.; O'Brien, L.; Zeng, H. T.; Lewis, E. R.; Petit, D.; Cowburn, R. P.

    2010-03-01

    Data storage devices based on magnetic domain walls (DWs) propagating through ferromagnetic nanowires have attracted a great deal of attention in recent years [1,2]. Here we experimentally demonstrate a shift register based on an open-ended chain of ferromagnetic NOT gates. When used in combination with a globally applied magnetic field such devices can support bi-directional data flow [3]. We have demonstrated data writing, propagation, and readout in individually addressable NiFe nanowires 90 nm wide and 10 nm thick. Up to eight data bits are electrically input to the device, stored for extended periods without power supplied to the device, and then output using either a first in first out or a last in first out mode of operation. Compared to traditional electronic transistor-based circuits, the inherent bi-directionality afforded by these DW logic gates offers a range of devices that are reversible and not limited to only one mode of operation. [1] S. S. Parkin, US Patent 6,834,005 (2004) [2] D. A. Allwod, et al., Science 309 (5741), 1688 (2005) [3] L. O'Brien, et al. accepted for publication in APL (2009)

  3. A linearly controlled direct-current power source for high-current inductive loads in a magnetic suspension wind tunnel

    NASA Technical Reports Server (NTRS)

    Tripp, John S.; Daniels, Taumi S.

    1990-01-01

    The NASA Langley 6 inch magnetic suspension and balance system (MSBS) requires an independently controlled bidirectional DC power source for each of six positioning electromagnets. These electromagnets provide five-degree-of-freedom control over a suspended aerodynamic test model. Existing power equipment, which employs resistance coupled thyratron controlled rectifiers as well as AC to DC motor generator converters, is obsolete, inefficient, and unreliable. A replacement six phase bidirectional controlled bridge rectifier is proposed, which employs power MOSFET switches sequenced by hybrid analog/digital circuits. Full load efficiency is 80 percent compared to 25 percent for the resistance coupled thyratron system. Current feedback provides high control linearity, adjustable current limiting, and current overload protection. A quenching circuit suppresses inductive voltage impulses. It is shown that 20 kHz interference from positioning magnet power into MSBS electromagnetic model position sensors results predominantly from capacitively coupled electric fields. Hence, proper shielding and grounding techniques are necessary. Inductively coupled magnetic interference is negligible.

  4. The topology of intrasector reversals of the interplanetary magnetic field

    NASA Astrophysics Data System (ADS)

    Kahler, S. W.; Crooker, N. U.; Gosling, J. T.

    1996-11-01

    A technique has been developed recently to determine the polarities of interplanetary magnetic fields relative to their origins at the Sun by comparing energetic electron flow directions with local magnetic field directions. Here we use heat flux electrons from the Los Alamos National Laboratory (LANL) plasma detector on the ISEE 3 spacecraft to determine the field polarities. We examine periods within well-defined magnetic sectors when the field directions appear to be reversed from the normal spiral direction of the sector. About half of these intrasector field reversals (IFRs) are cases in which the polarities match those of the surrounding sectors, indicating that those fields have been folded back toward the Sun. The more interesting cases are those with polarity reversals. We find no clear cases of isolated reverse polarity fields, which suggests that islands of reverse polarity in the solar source dipole field probably do not exist. The IFRs with polarity reversals are strongly associated with periods of bidirectional electron flows, suggesting that those fields occur only in conjunction with closed fields. We propose that both those IFRs and the bidirectional flows are signatures of coronal mass ejections (CMEs). In that case, many interplanetary CMEs are larger and more complex than previously thought, consisting of both open and closed field components.

  5. Where in the Marsh is the Water (and When)?: Measuring and modeling salt marsh hydrology for ecological and biogeochemical applications

    EPA Science Inventory

    Salt marsh hydrology presents many difficulties from a measurement and modeling standpoint: the bi-directional flows of tidal waters, variable water densities due to mixing of fresh and salt water, significant influences from vegetation, and complex stream morphologies. Because o...

  6. The emergence and diffusion of DNA microarray technology.

    PubMed

    Lenoir, Tim; Giannella, Eric

    2006-08-22

    The network model of innovation widely adopted among researchers in the economics of science and technology posits relatively porous boundaries between firms and academic research programs and a bi-directional flow of inventions, personnel, and tacit knowledge between sites of university and industry innovation. Moreover, the model suggests that these bi-directional flows should be considered as mutual stimulation of research and invention in both industry and academe, operating as a positive feedback loop. One side of this bi-directional flow--namely; the flow of inventions into industry through the licensing of university-based technologies--has been well studied; but the reverse phenomenon of the stimulation of university research through the absorption of new directions emanating from industry has yet to be investigated in much detail. We discuss the role of federal funding of academic research in the microarray field, and the multiple pathways through which federally supported development of commercial microarray technologies have transformed core academic research fields. Our study confirms the picture put forward by several scholars that the open character of networked economies is what makes them truly innovative. In an open system innovations emerge from the network. The emergence and diffusion of microarray technologies we have traced here provides an excellent example of an open system of innovation in action. Whether they originated in a startup company environment that operated like a think-tank, such as Affymax, the research labs of a large firm, such as Agilent, or within a research university, the inventors we have followed drew heavily on knowledge resources from all parts of the network in bringing microarray platforms to light. Federal funding for high-tech startups and new industrial development was important at several phases in the early history of microarrays, and federal funding of academic researchers using microarrays was fundamental to transforming the research agendas of several fields within academe. The typical story told about the role of federal funding emphasizes the spillovers from federally funded academic research to industry. Our study shows that the knowledge spillovers worked both ways, with federal funding of non-university research providing the impetus for reshaping the research agendas of several academic fields.

  7. The emergence and diffusion of DNA microarray technology

    PubMed Central

    Lenoir, Tim; Giannella, Eric

    2006-01-01

    The network model of innovation widely adopted among researchers in the economics of science and technology posits relatively porous boundaries between firms and academic research programs and a bi-directional flow of inventions, personnel, and tacit knowledge between sites of university and industry innovation. Moreover, the model suggests that these bi-directional flows should be considered as mutual stimulation of research and invention in both industry and academe, operating as a positive feedback loop. One side of this bi-directional flow – namely; the flow of inventions into industry through the licensing of university-based technologies – has been well studied; but the reverse phenomenon of the stimulation of university research through the absorption of new directions emanating from industry has yet to be investigated in much detail. We discuss the role of federal funding of academic research in the microarray field, and the multiple pathways through which federally supported development of commercial microarray technologies have transformed core academic research fields. Our study confirms the picture put forward by several scholars that the open character of networked economies is what makes them truly innovative. In an open system innovations emerge from the network. The emergence and diffusion of microarray technologies we have traced here provides an excellent example of an open system of innovation in action. Whether they originated in a startup company environment that operated like a think-tank, such as Affymax, the research labs of a large firm, such as Agilent, or within a research university, the inventors we have followed drew heavily on knowledge resources from all parts of the network in bringing microarray platforms to light. Federal funding for high-tech startups and new industrial development was important at several phases in the early history of microarrays, and federal funding of academic researchers using microarrays was fundamental to transforming the research agendas of several fields within academe. The typical story told about the role of federal funding emphasizes the spillovers from federally funded academic research to industry. Our study shows that the knowledge spillovers worked both ways, with federal funding of non-university research providing the impetus for reshaping the research agendas of several academic fields. PMID:16925816

  8. Detailed validation of the bidirectional effect in various Case 1 waters for application to ocean color imagery

    NASA Astrophysics Data System (ADS)

    Voss, K. J.; Morel, A.; Antoine, D.

    2007-09-01

    The radiance viewed from the ocean depends on the illumination and viewing geometry along with the water properties, and this variation is called the bidirectional effect. This bidirectional effect depends on the inherent optical properties of the water, including the volume scattering function, and is important when comparing data from different satellite sensors. The current model of f/Q, which contains the bidirectional effect, by Morel et al. (2002) depends on modeled, not measured, water parameters, thus must be carefully validated. In this paper we combined upwelling radiance distribution data from several cruises, in varied water types and with a wide range of solar zenith angles. We compared modeled and measured Lview/Lnadir and found that the average difference between the model and data was less than 0.01, while the RMS difference between the model and data was on the order of 0.02-0.03. This is well within the statistical noise of the data, which was on the order of 0.04-0.05, due to environmental noise sources such as wave focusing.

  9. Bidirectional relations between parenting practices and child externalizing behavior: a cross-lagged panel analysis in the context of a psychosocial treatment and 3-year follow-up.

    PubMed

    Shaffer, Anne; Lindhiem, Oliver; Kolko, David J; Trentacosta, Christopher J

    2013-02-01

    In the current study, we examined longitudinal changes in, and bidirectional effects between, parenting practices and child behavior problems in the context of a psychosocial treatment and 3-year follow-up period. The sample comprised 139 parent-child dyads (child ages 6-11) who participated in a modular treatment protocol for early-onset ODD or CD. Parenting practices and child behavior problems were assessed at six time-points using multiple measures and multiple reporters. The data were analyzed using cross-lagged panel analyses. Results indicated robust temporal stabilities of parenting practices and child behavior problems, in the context of treatment-related improvements, but bidirectional effects between parenting practices and child behavior were less frequently detected. Our findings suggest that bidirectional effects are relatively smaller than the temporal stability of each construct for school-age children with ODD/CD and their parents, following a multi-modal clinical intervention that is directed at both parents and children. Implications for treatment and intervention are discussed.

  10. Towards public health decision support: a systematic review of bidirectional communication approaches.

    PubMed

    Dixon, Brian E; Gamache, Roland E; Grannis, Shaun J

    2013-05-01

    To summarize the literature describing computer-based interventions aimed at improving bidirectional communication between clinical and public health. A systematic review of English articles using MEDLINE and Google Scholar. Search terms included public health, epidemiology, electronic health records, decision support, expert systems, and decision-making. Only articles that described the communication of information regarding emerging health threats from public health agencies to clinicians or provider organizations were included. Each article was independently reviewed by two authors. Ten peer-reviewed articles highlight a nascent but promising area of research and practice related to alerting clinicians about emerging threats. Current literature suggests that additional research and development in bidirectional communication infrastructure should focus on defining a coherent architecture, improving interoperability, establishing clear governance, and creating usable systems that will effectively deliver targeted, specific information to clinicians in support of patient and population decision-making. Increasingly available clinical information systems make it possible to deliver timely, relevant knowledge to frontline clinicians in support of population health. Future work should focus on developing a flexible, interoperable infrastructure for bidirectional communications capable of integrating public health knowledge into clinical systems and workflows.

  11. Reciprocal relations between perceived parental knowledge and adolescent substance use and delinquency: The moderating role of parent-teen relationship quality.

    PubMed

    Abar, Caitlin C; Jackson, Kristina M; Wood, Mark

    2014-09-01

    The current study prospectively examined hypothesized short- and long-term reciprocal relations between perceived parental knowledge and adolescent heavy episodic drinking, marijuana use, and delinquency. Using the contextual model of parenting style (Darling & Steinberg, 1993), we examined the extent to which the bidirectional nature of associations between knowledge and adolescent outcomes is dependent on a facet of parenting style: the quality of the parent-child relationship. Data came from the first 4 waves of the National Longitudinal Study of Youth 1997. The sample for the current study consisted of 5,419 students between 12 and 14 years of age at baseline (52% male) surveyed annually for 4 years. Parallel process, autoregressive latent trajectory models were used to examine relations between initial levels and change over time in perceived parental knowledge and adolescent risk, and short-term cross-lagged paths were included to examine bidirectionality while accounting for long-term associations. Results showed significant short-term and long-term bidirectionality between perceived parental knowledge and adolescent outcomes, with parent effects on students and student effects on parents. Long-term associations across constructs were negative, whereas short-term associations were positive. These reciprocal associations were shown to differ across levels of parent-child relationship quality with regard to adolescent heavy episodic drinking and delinquency, providing support for the contextual model of parenting style. Implications for future work on parent-child bidirectional relationships and parent-based interventions are discussed.

  12. Controllable Bidirectional dc Power Sources For Large Loads

    NASA Technical Reports Server (NTRS)

    Tripp, John S.; Daniels, Taumi S.

    1995-01-01

    System redesigned for greater efficiency, durability, and controllability. Modern electronically controlled dc power sources proposed to supply currents to six electromagnets used to position aerodynamic test model in wind tunnel. Six-phase bridge rectifier supplies load with large current at voltage of commanded magnitude and polarity. Current-feedback circuit includes current-limiting feature giving some protection against overload.

  13. Interannual variability of sorted bedforms in the coastal German Bight (SE North Sea)

    NASA Astrophysics Data System (ADS)

    Mielck, F.; Holler, P.; Bürk, D.; Hass, H. C.

    2015-12-01

    Sorted bedforms are ubiquitous on the inner continental shelves worldwide. They are described as spatially-grain-size-sorted features consisting of small rippled medium-to-coarse sand and can remain stable for decades. However, the knowledge about their genesis and development is still fragmentary. For this study, a representative investigation area (water depth<15 m) located on the shelf west of the island of Sylt (SE North Sea, Germany) was periodically surveyed with hydroacoustic means (i.e. sidescan sonar, multibeam echo sounder, and sub-bottom profiler) during 2010-2014. Since this area is influenced by tidal and wind-driven currents, the aim was to detect and examine interannual variabilities in the characteristics of the prevailing sorted bedforms. Our measurements reveal sinuous stripes of rippled medium sand which are embedded in shallow symmetrical depressions. These domains are surrounded by relatively smooth fine-sand areas. These sorted bedforms were identified as flow-transverse features that are maintained by ebb and flood currents of almost equal strengths that flow in opposite directions. This bidirectional flow field generates sharp boundaries between the medium- and fine-sand domains in both current directions. Further to the north, where flood currents are dominant, asymmetric sorted bedforms were detected which show sharp boundaries only in flood-current direction. Comparisons between the measurements of the different years show no significant variations in morphology and distribution of the sorted bedforms. However, variations of the boundaries between the medium and the fine-sand domains were observed. Additionally, new minor sorted bedforms and rippled excavation marks as well as new fine-sand areas developed and disappeared occasionally. It can be supposed that such sediment winnowing and focusing processes take place during periodically recurring storm surges, which change the shapes of the features. Moreover, variations in alignments and sizes of the small ripple formations were detected. They seem to indicate the directions and intensities of previous storm events.

  14. Real-time display of flow-pressure-volume loops.

    PubMed

    Morozoff, P E; Evans, R W

    1992-01-01

    Graphic display of respiratory waveforms can be valuable for monitoring the progress of ventilated patients. A system has been developed that can display flow-pressure-volume loops as derived from a patient's respiratory circuit in real time. It can also display, store, print, and retrieve ventilatory waveforms. Five loops can be displayed at once: current, previous, reference, "ideal," and previously saved. Two components, the data-display device (DDD) and the data-collection device (DCD), comprise the system. An IBM 286/386 computer with a graphics card (VGA) and bidirectional parallel port is used for the DDD; an eight-bit microprocessor card and an A/D convertor card make up the DCD. A real-time multitasking operating system was written to control the DDD, while the DCD operates from in-line assembly code. The DCD samples the pressure and flow sensors at 100 Hz and looks for a complete flow waveform pattern based on flow slope. These waveforms are then passed to the DDD via the mutual parallel port. Within the DDD a process integrates the flow to create a volume signal and performs a multilinear regression on the pressure, flow, and volume data to calculate the elastance, resistance, pressure offset, and coefficient of determination. Elastance, resistance, and offset are used to calculate Pr and Pc where: Pr[k] = P[k]-offset-(elastance.V[k]) and Pc[k] = P[k]-offset-(resistance.F[k]). Volume vs. Pc and flow vs. Pr can be displayed in real time. Patient data from previous clinical tests were loaded into the device to verify the software calculations. An analog waveform generator was used to simulate flow and pressure waveforms that validated the system.(ABSTRACT TRUNCATED AT 250 WORDS)

  15. Injection and swirl driven flowfields in solid and liquid rocket motors

    NASA Astrophysics Data System (ADS)

    Vyas, Anand B.

    In this work, we seek approximate analytical solutions to describe the bulk flow motion in certain types of solid and liquid rocket motors. In the case of an idealized solid rocket motor, a cylindrical double base propellant grain with steady regression rate is considered. The well known inviscid profile determined by Culick is extended here to include the effects of viscosity and steady grain regression. The approximate analytical solution for the cold flow is obtained from similarity principles, perturbation methods and the method of variation of parameters. The velocity, vorticity, pressure gradient and the shear stress distributions are determined and interpreted for different rates of wall regression and injection Reynolds number. The liquid propellant rocket engine considered here is based on a novel design that gives rise to a cyclonic flow. The resulting bidirectional motion is triggered by the tangential injection of an oxidizer just upstream of the chamber nozzle. Velocity, vorticity and pressure gradient distributions are determined for the bulk gas dynamics using a non-reactive inviscid model. Viscous corrections are then incorporated to explain the formation of a forced vortex near the core. Our results compare favorably with numerical simulations and experimental measurements obtained by other researchers. They also indicate that the bidirectional vortex in a cylindrical chamber is a physical solution of the Euler equations. In closing, we investigate the possibility of multi-directional flow behavior as predicted by Euler's equation and as reported recently in laboratory experiments.

  16. Incorporating ecogeomorphic feedbacks to better understand resiliency in streams: A review and directions forward

    NASA Astrophysics Data System (ADS)

    Atkinson, Carla L.; Allen, Daniel C.; Davis, Lisa; Nickerson, Zachary L.

    2018-03-01

    Decades of interdisciplinary research show river form and function depends on interactions between the living and nonliving world, but a dominant paradigm underlying ecogeomorphic work consists of a top-down, unidirectional approach with abiotic forces driving biotic systems. Stream form and location within the stream network does dictate the habitat and resources available for organisms and overall community structure. Yet this traditional hierarchal framework on its own is inadequate in communicating information regarding the influence of biological systems on fluvial geomorphology that lead to changes in channel morphology, sediment cycling, and system-scale functions (e.g., sediment yield, biogeochemical nutrient cycling). Substantial evidence that organisms influence fluvial geomorphology exists, specifically the ability of aquatic vegetation and lotic animals to modify flow velocities and sediment deposition and transport - thus challenging the traditional hierarchal framework. Researchers recognize the need for ecogeomorphic frameworks that conceptualize feedbacks between organisms, sediment transport, and geomorphic structure. Furthermore, vital ecosystem processes, such as biogeochemical nutrient cycling represent the conversations that are occurring between geomorphological and biological systems. Here we review and synthesize selected case studies highlighting the role organisms play in moderating geomorphic processes and likely interact with these processes to have an impact on an essential ecosystem process, biogeochemical nutrient recycling. We explore whether biophysical interactions can provide information essential to improving predictions of system-scale river functions, specifically sediment transport and biogeochemical cycling, and discuss tools used to study these interactions. We suggest that current conceptual frameworks should acknowledge that hydrologic, geomorphologic, and ecologic processes operate on different temporal scales, generating bidirectional feedback loops over space and time. Hydro- and geomorphologic processes, operating episodically during bankfull conditions, influence ecological processes (e.g., biogeochemical cycling) occurring over longer time periods during base-flow conditions. This ecological activity generates the antecedent conditions that influence the hydro- and geomorphologic processes occurring during the next high flow event, creating a bidirectional feedback. This feedback should enhance the resiliency of fluvial landforms and ecosystem processes, allowing physical and biological processes to pull and push against each other over time.

  17. High-Resolution Analysis of Human Y-Chromosome Variation Shows a Sharp Discontinuity and Limited Gene Flow between Northwestern Africa and the Iberian Peninsula

    PubMed Central

    Bosch, Elena; Calafell, Francesc; Comas, David; Oefner, Peter J.; Underhill, Peter A.; Bertranpetit, Jaume

    2001-01-01

    In the present study we have analyzed 44 Y-chromosome biallelic polymorphisms in population samples from northwestern (NW) Africa and the Iberian Peninsula, which allowed us to place each chromosome unequivocally in a phylogenetic tree based on >150 polymorphisms. The most striking results are that contemporary NW African and Iberian populations were found to have originated from distinctly different patrilineages and that the Strait of Gibraltar seems to have acted as a strong (although not complete) barrier to gene flow. In NW African populations, an Upper Paleolithic colonization that probably had its origin in eastern Africa contributed 75% of the current gene pool. In comparison, ∼78% of contemporary Iberian Y chromosomes originated in an Upper Paleolithic expansion from western Asia, along the northern rim of the Mediterranean basin. Smaller contributions to these gene pools (constituting 13% of Y chromosomes in NW Africa and 10% of Y chromosomes in Iberia) came from the Middle East during the Neolithic and, during subsequent gene flow, from Sub-Saharan to NW Africa. Finally, bidirectional gene flow across the Strait of Gibraltar has been detected: the genetic contribution of European Y chromosomes to the NW African gene pool is estimated at 4%, and NW African populations may have contributed 7% of Iberian Y chromosomes. The Islamic rule of Spain, which began in a.d. 711 and lasted almost 8 centuries, left only a minor contribution to the current Iberian Y-chromosome pool. The high-resolution analysis of the Y chromosome allows us to separate successive migratory components and to precisely quantify each historical layer. PMID:11254456

  18. Bidirectional Controlled Joint Remote State Preparation via a Seven-Qubit Entangled State

    NASA Astrophysics Data System (ADS)

    Wang, Xiao-yu; Mo, Zhi-wen

    2017-04-01

    A new protocol for implementing five-party bidirectional controlled joint remote state preparation is proposed by using a seven-qubit entangled state as the quantum channel. It can be shown that two distant senders can simultaneously and deterministically exchange their states with the other senders under the control of the supervisor, and it cannot be succeed without permission of the controller. Only pauli operation and single-qubit measurement are used in our scheme, so the scheme with five-party is feasible within the reach of current technologies.

  19. Impulsive Personality and Alcohol Use: Bidirectional Relations Over One Year

    PubMed Central

    Kaiser, Alison; Bonsu, Jacqueline A.; Charnigo, Richard J.; Milich, Richard; Lynam, Donald R.

    2016-01-01

    Objective: Impulsive personality traits have been found to be robust predictors of substance use and problems in both cross-sectional and longitudinal research. Studies examining the relations of substance use and impulsive personality over time indicate a bidirectional relation, where substance use is also predictive of increases in later impulsive personality. The present study sought to build on these findings by examining the bidirectional relations among the different impulsive personality traits assessed by the UPPS-P Impulsive Behavior Scale, with an interest in urgency (the tendency to act rashly when experiencing strong affect). Method: Participants were 525 first-year college students (48.0% male, 81.1% White), who completed self-report measures assessing personality traits and a structured interview assessing past and current substance use. Data collection took place at two different time points: the first occurred during the participants’ first year of college, and the second occurred approximately 1 year later. Bidirectional relations were examined using structural equation modeling. Results: Time 1 (T1) positive urgency predicted higher levels of alcohol use at Time 2 (T2), whereas T1 lack of perseverance predicted lower levels of alcohol use at T2. T1 alcohol use predicted higher levels of positive urgency, negative urgency, sensation seeking, and lack of premeditation at T2. Conclusions: Findings provide greater resolution in characterizing the bidirectional relation between impulsive personality traits and substance use. PMID:27172580

  20. Development and evaluation of an ammonia bidirectional flux parameterization for air quality models

    NASA Astrophysics Data System (ADS)

    Pleim, Jonathan E.; Bash, Jesse O.; Walker, John T.; Cooter, Ellen J.

    2013-05-01

    is an important contributor to particulate matter in the atmosphere and can significantly impact terrestrial and aquatic ecosystems. Surface exchange between the atmosphere and biosphere is a key part of the ammonia cycle. New modeling techniques are being developed for use in air quality models that replace current ammonia emissions from fertilized crops and ammonia dry deposition with a bidirectional surface flux model including linkage to a detailed biogeochemical and farm management model. Recent field studies involving surface flux measurements over crops that predominate in North America have been crucial for extending earlier bidirectional flux models toward more realistic treatment of NH3 fluxes for croplands. Comparisons of the ammonia bidirection flux algorithm to both lightly fertilized soybeans and heavily fertilized corn demonstrate that the model can capture the magnitude and dynamics of observed ammonia fluxes, both net deposition and evasion, over a range of conditions with overall biases on the order of the uncertainty of the measurements. However, successful application to the field experiment in heavily fertilized corn required substantial modification of the model to include new parameterizations for in-soil diffusion resistance, ground quasi-laminar boundary layer resistance, and revised cuticular resistance that is dependent on in-canopy NH3 concentration and RH at the leaf surface. This new bidirectional flux algorithm has been incorporated in an air quality modeling system, which also includes an implementation of a soil nitrification model.

  1. Reversed portal flow: Clinical influence on the long-term outcomes in cirrhosis.

    PubMed

    Kondo, Takayuki; Maruyama, Hitoshi; Sekimoto, Tadashi; Shimada, Taro; Takahashi, Masanori; Yokosuka, Osamu

    2015-08-07

    To elucidate the natural history and the longitudinal outcomes in cirrhotic patients with non-forward portal flow (NFPF). The present retrospective study consisted of 222 cirrhotic patients (120 males and 102 females; age, 61.7 ± 11.1 years). The portal hemodynamics were evaluated at baseline and during the observation period using both pulsed and color Doppler ultrasonography. The diameter (mm), flow direction, mean flow velocity (cm/s), and mean flow volume (mL/min) were assessed at the portal trunk, the splenic vein, the superior mesenteric vein, and the collateral vessels. The average values from 2 to 4 measurements were used for the data analysis. The portal flow direction was defined as follows: forward portal flow (FPF) for continuous hepatopetal flow; bidirectional flow for to-and-fro flow; and reversed flow for continuous hepatofugal flow. The bidirectional flow and the reversed flow were classified as NFPF in this study. The clinical findings and prognosis were compared between the patients with FPF and those with NFPF. The median follow-up period was 40.9 mo (range, 0.3-156.5 mo). Twenty-four patients (10.8%) demonstrated NFPF, accompanied by lower albumin level, worse Child-Pugh scores, and model for end-stage liver disease scores. The portal hemodynamic features in the patients with NFPF were smaller diameter of the portal trunk; presence of short gastric vein, splenorenal shunt, or inferior mesenteric vein; and advanced collateral vessels (diameter > 8.7 mm, flow velocity > 10.2 cm/s, and flow volume > 310 mL/min). The cumulative incidence rates of NFPF were 6.5% at 1 year, 14.5% at 3 years, and 23.1% at 5 years. The collateral vessels characterized by flow velocity > 9.5 cm/s and those located at the splenic hilum were significant predictive factors for developing NFPF. The cumulative survival rate was significantly lower in the patients with NFPF (72.2% at 1 year, 38.5% at 3 years, 38.5% at 5 years) than in those with forward portal flow (84.0% at 1 year, 67.8% at 3 years, 54.3% at 5 years, P = 0.0123) using the Child-Pugh B and C classifications. NFPF has a significant negative effect on the prognosis of patients with worse liver function reserve, suggesting the need for careful management.

  2. Reversed portal flow: Clinical influence on the long-term outcomes in cirrhosis

    PubMed Central

    Kondo, Takayuki; Maruyama, Hitoshi; Sekimoto, Tadashi; Shimada, Taro; Takahashi, Masanori; Yokosuka, Osamu

    2015-01-01

    AIM: To elucidate the natural history and the longitudinal outcomes in cirrhotic patients with non-forward portal flow (NFPF). METHODS: The present retrospective study consisted of 222 cirrhotic patients (120 males and 102 females; age, 61.7 ± 11.1 years). The portal hemodynamics were evaluated at baseline and during the observation period using both pulsed and color Doppler ultrasonography. The diameter (mm), flow direction, mean flow velocity (cm/s), and mean flow volume (mL/min) were assessed at the portal trunk, the splenic vein, the superior mesenteric vein, and the collateral vessels. The average values from 2 to 4 measurements were used for the data analysis. The portal flow direction was defined as follows: forward portal flow (FPF) for continuous hepatopetal flow; bidirectional flow for to-and-fro flow; and reversed flow for continuous hepatofugal flow. The bidirectional flow and the reversed flow were classified as NFPF in this study. The clinical findings and prognosis were compared between the patients with FPF and those with NFPF. The median follow-up period was 40.9 mo (range, 0.3-156.5 mo). RESULTS: Twenty-four patients (10.8%) demonstrated NFPF, accompanied by lower albumin level, worse Child-Pugh scores, and model for end-stage liver disease scores. The portal hemodynamic features in the patients with NFPF were smaller diameter of the portal trunk; presence of short gastric vein, splenorenal shunt, or inferior mesenteric vein; and advanced collateral vessels (diameter > 8.7 mm, flow velocity > 10.2 cm/s, and flow volume > 310 mL/min). The cumulative incidence rates of NFPF were 6.5% at 1 year, 14.5% at 3 years, and 23.1% at 5 years. The collateral vessels characterized by flow velocity > 9.5 cm/s and those located at the splenic hilum were significant predictive factors for developing NFPF. The cumulative survival rate was significantly lower in the patients with NFPF (72.2% at 1 year, 38.5% at 3 years, 38.5% at 5 years) than in those with forward portal flow (84.0% at 1 year, 67.8% at 3 years, 54.3% at 5 years, P = 0.0123) using the Child-Pugh B and C classifications. CONCLUSION: NFPF has a significant negative effect on the prognosis of patients with worse liver function reserve, suggesting the need for careful management. PMID:26269679

  3. Shooting method for solution of boundary-layer flows with massive blowing

    NASA Technical Reports Server (NTRS)

    Liu, T.-M.; Nachtsheim, P. R.

    1973-01-01

    A modified, bidirectional shooting method is presented for solving boundary-layer equations under conditions of massive blowing. Unlike the conventional shooting method, which is unstable when the blowing rate increases, the proposed method avoids the unstable direction and is capable of solving complex boundary-layer problems involving mass and energy balance on the surface.

  4. Decoding Network Structure in On-Chip Integrated Flow Cells with Synchronization of Electrochemical Oscillators

    NASA Astrophysics Data System (ADS)

    Jia, Yanxin; Kiss, István Z.

    2017-04-01

    The analysis of network interactions among dynamical units and the impact of the coupling on self-organized structures is a challenging task with implications in many biological and engineered systems. We explore the coupling topology that arises through the potential drops in a flow channel in a lab-on-chip device that accommodates chemical reactions on electrode arrays. The networks are revealed by analysis of the synchronization patterns with the use of an oscillatory chemical reaction (nickel electrodissolution) and are further confirmed by direct decoding using phase model analysis. In dual electrode configuration, a variety coupling schemes, (uni- or bidirectional positive or negative) were identified depending on the relative placement of the reference and counter electrodes (e.g., placed at the same or the opposite ends of the flow channel). With three electrodes, the network consists of a superposition of a localized (upstream) and global (all-to-all) coupling. With six electrodes, the unique, position dependent coupling topology resulted spatially organized partial synchronization such that there was a synchrony gradient along the quasi-one-dimensional spatial coordinate. The networked, electrode potential (current) spike generating electrochemical reactions hold potential for construction of an in-situ information processing unit to be used in electrochemical devices in sensors and batteries.

  5. Darcy-Forchheimer Three-Dimensional Flow of Williamson Nanofluid over a Convectively Heated Nonlinear Stretching Surface

    NASA Astrophysics Data System (ADS)

    Hayat, Tasawar; Aziz, Arsalan; Muhammad, Taseer; Alsaedi, Ahmed

    2017-09-01

    The present study elaborates three-dimensional flow of Williamson nanoliquid over a nonlinear stretchable surface. Fluid flow obeys Darcy-Forchheimer porous medium. A bidirectional nonlinear stretching surface generates the flow. Convective surface condition of heat transfer is taken into consideration. Further the zero nanoparticles mass flux condition is imposed at the boundary. Effects of thermophoresis and Brownian diffusion are considered. Assumption of boundary layer has been employed in the problem formulation. Convergent series solutions for the nonlinear governing system are established through the optimal homotopy analysis method (OHAM). Graphs have been sketched in order to analyze that how the velocity, temperature and concentration distributions are affected by distinct emerging flow parameters. Skin friction coefficients and local Nusselt number are also computed and discussed.

  6. Bidirectional composition on lie groups for gradient-based image alignment.

    PubMed

    Mégret, Rémi; Authesserre, Jean-Baptiste; Berthoumieu, Yannick

    2010-09-01

    In this paper, a new formulation based on bidirectional composition on Lie groups (BCL) for parametric gradient-based image alignment is presented. Contrary to the conventional approaches, the BCL method takes advantage of the gradients of both template and current image without combining them a priori. Based on this bidirectional formulation, two methods are proposed and their relationship with state-of-the-art gradient based approaches is fully discussed. The first one, i.e., the BCL method, relies on the compositional framework to provide the minimization of the compensated error with respect to an augmented parameter vector. The second one, the projected BCL (PBCL), corresponds to a close approximation of the BCL approach. A comparative study is carried out dealing with computational complexity, convergence rate and frequence of convergence. Numerical experiments using a conventional benchmark show the performance improvement especially for asymmetric levels of noise, which is also discussed from a theoretical point of view.

  7. A Novel User Created Message Application Service Design for Bidirectional TPEG

    NASA Astrophysics Data System (ADS)

    Lee, Sang-Hee; Jo, Kang-Hyun

    The T-DMB (Terrestrial-Digital Multimedia Broadcasting) is the national service, currently successful in use in Korea since 2008. Among other services, TPEG (Transport Protocol Experts Group) service has been spotlighted in the aspects of creating earnings. At present, TPEG service is not so popular as it fails to satisfy the user’s demands on various aspects. Thus, the variety of services including bidirectional service is necessary in stage of DMB2.0. In this paper, the limitations of existing TPEG-POI (Point of Interest) application service using the wireless communication network are indicated. To overcome such limitations, we propose a business model for TPEG-UCM (User Created Message) application service which uses individual bidirectional media. The experiment shown in this paper proves the usability and operability of the proposed method, suggesting that the implementation of the proposed method would be overcome a lack of variety and unidirectional of existing TPEG application.

  8. Collaborative and Bidirectional Feedback Between Students and Clinical Preceptors: Promoting Effective Communication Skills on Health Care Teams.

    PubMed

    Myers, Kara; Chou, Calvin L

    2016-11-01

    Current literature on feedback suggests that clinical preceptors lead feedback conversations that are primarily unidirectional, from preceptor to student. While this approach may promote clinical competency, it does not actively develop students' competency in facilitating feedback discussions and providing feedback across power differentials (ie, from student to preceptor). This latter competency warrants particular attention given its fundamental role in effective health care team communication and its related influence on patient safety. Reframing the feedback process as collaborative and bidirectional, where both preceptors and students provide and receive feedback, maximizes opportunities for role modeling and skills practice in the context of a supportive relationship, thereby enhancing team preparedness. We describe an initiative to introduce these fundamental skills of collaborative, bidirectional feedback in the nurse-midwifery education program at the University of California, San Francisco. © 2016 by the American College of Nurse-Midwives.

  9. Bidirectional Relations of Impulsive Personality and Alcohol Use Across Three Waves of Data Collection.

    PubMed

    Kaiser, Alison J; Davis, Heather A; Milich, Richard; Smith, Gregory T; Charnigo, Richard

    2018-06-11

    To explore the bidirectional relations between alcohol use and three impulsive personality traits, to advance understanding of risk processes. 525 college students (mean age = 18.95 years) recruited in August 2008 and 2009 and followed up annually for three years. Personality and past/current substance use were assessed. T2 sensation seeking mediated the predictive relationship between T1 and T3 alcohol use, and T2 alcohol use mediated the predictive relationship between T1 and T3 sensation seeking. In addition, T2 alcohol problems mediated the predictive relationship between T1 alcohol use and T3 negative urgency. Findings support a bidirectional relationship between sensation seeking and alcohol use, and drinking anticipates drinking problems, which predict increases in negative urgency. For some individuals, there appears to be an ongoing process of increased risk in the form of increases in both drinking and high-risk personality traits.

  10. Bidirectional Associations Between Externalizing Behavior Problems and Maladaptive Parenting Within Parent-Son Dyads Across Childhood

    PubMed Central

    Loeber, Rolf; Hinshaw, Stephen P.; Pardini, Dustin A.

    2018-01-01

    Coercive parent–child interaction models posit that an escalating cycle of negative, bidirectional interchanges influences the development of boys’ externalizing problems and caregivers’ maladaptive parenting over time. However, longitudinal studies examining this hypothesis have been unable to rule out the possibility that between-individual factors account for bidirectional associations between child externalizing problems and maladaptive parenting. Using a longitudinal sample of boys (N = 503) repeatedly assessed eight times across 6-month intervals in childhood (in a range between 6 and 13 years), the current study is the first to use novel within-individual change (fixed effects) models to examine whether parents tend to increase their use of maladaptive parenting strategies following an increase in their son’s externalizing problems, or vice versa. These bidirectional associations were examined using multiple facets of externalizing problems (i.e., interpersonal callousness, conduct and oppositional defiant problems, hyperactivity/impulsivity) and parenting behaviors (i.e., physical punishment, involvement, parent–child communication). Analyses failed to support the notion that when boys increase their typical level of problem behaviors, their parents show an increase in their typical level of maladaptive parenting across the subsequent 6 month period, and vice versa. Instead, across 6-month intervals, within parent-son dyads, changes in maladaptive parenting and child externalizing problems waxed and waned in concert. Fixed effects models to address the topic of bidirectional relations between parent and child behavior are severely underrepresented. We recommend that other researchers who have found significant bidirectional parent–child associations using rank-order change models reexamine their data to determine whether these findings hold when examining changes within parent–child dyads. PMID:26780209

  11. Bidirectional Associations Between Externalizing Behavior Problems and Maladaptive Parenting Within Parent-Son Dyads Across Childhood.

    PubMed

    Besemer, Sytske; Loeber, Rolf; Hinshaw, Stephen P; Pardini, Dustin A

    2016-10-01

    Coercive parent-child interaction models posit that an escalating cycle of negative, bidirectional interchanges influences the development of boys' externalizing problems and caregivers' maladaptive parenting over time. However, longitudinal studies examining this hypothesis have been unable to rule out the possibility that between-individual factors account for bidirectional associations between child externalizing problems and maladaptive parenting. Using a longitudinal sample of boys (N = 503) repeatedly assessed eight times across 6-month intervals in childhood (in a range between 6 and 13 years), the current study is the first to use novel within-individual change (fixed effects) models to examine whether parents tend to increase their use of maladaptive parenting strategies following an increase in their son's externalizing problems, or vice versa. These bidirectional associations were examined using multiple facets of externalizing problems (i.e., interpersonal callousness, conduct and oppositional defiant problems, hyperactivity/impulsivity) and parenting behaviors (i.e., physical punishment, involvement, parent-child communication). Analyses failed to support the notion that when boys increase their typical level of problem behaviors, their parents show an increase in their typical level of maladaptive parenting across the subsequent 6 month period, and vice versa. Instead, across 6-month intervals, within parent-son dyads, changes in maladaptive parenting and child externalizing problems waxed and waned in concert. Fixed effects models to address the topic of bidirectional relations between parent and child behavior are severely underrepresented. We recommend that other researchers who have found significant bidirectional parent-child associations using rank-order change models reexamine their data to determine whether these findings hold when examining changes within parent-child dyads.

  12. Feral rice from introgression of weedy rice genes into transgenic herbicide-resistant hybrid-rice progeny.

    PubMed

    Zhang, Jingxu; Kang, Ye; Valverde, Bernal E; Dai, Weimin; Song, Xiaoling; Qiang, Sheng

    2018-06-05

    Pollen-mediated herbicide-resistance transgene flow occurs bidirectionally between transgenic cultivated rice and weedy rice. The potential risk of weedy traits introgressing into hybrid rice is underestimated and poorly understood. Two of each glufosinate-resistant transgenic rice varieties and hybrid rice (F1) and their succeeding generations (F2-F4) were planted for three years in weedy-rice-free field plots adjacent to experimental weedy-rice fields. Weedy-rice-like (feral) plants, both glufosinate-resistant and with red-pericarp seed, were initially found only among the F3 generations of the two glufosinate-resistant transgenic hybrid rice. The composite fitness (an index based on eight productivity and weediness traits) of the feral progeny was significantly higher than that of glufosinate-resistant transgenic hybrid rice (the original female parent of feral progeny) under common monoculture garden conditions. Hybrid rice progeny segregated into individuals of variable height and extended flowering. Hybrid rice F2 generations had higher outcrossing rates by pollen reception (0.96%-1.65%) than their progenitors (0.07%-0.98%). Herbicide-resistant weedy rice can rapidly arise by pollen-mediated gene flow from weedy to transgenic hybrid rice. Their segregating pollen-receptive progeny pose greater agro-ecological risk than transgenic varieties. The safety assessment and management regulations for transgenic hybrid rice should take into account the risk of bidirectional gene flow.

  13. Towards public health decision support: a systematic review of bidirectional communication approaches

    PubMed Central

    Dixon, Brian E; Gamache, Roland E; Grannis, Shaun J

    2013-01-01

    Objective To summarize the literature describing computer-based interventions aimed at improving bidirectional communication between clinical and public health. Materials and Methods A systematic review of English articles using MEDLINE and Google Scholar. Search terms included public health, epidemiology, electronic health records, decision support, expert systems, and decision-making. Only articles that described the communication of information regarding emerging health threats from public health agencies to clinicians or provider organizations were included. Each article was independently reviewed by two authors. Results Ten peer-reviewed articles highlight a nascent but promising area of research and practice related to alerting clinicians about emerging threats. Current literature suggests that additional research and development in bidirectional communication infrastructure should focus on defining a coherent architecture, improving interoperability, establishing clear governance, and creating usable systems that will effectively deliver targeted, specific information to clinicians in support of patient and population decision-making. Conclusions Increasingly available clinical information systems make it possible to deliver timely, relevant knowledge to frontline clinicians in support of population health. Future work should focus on developing a flexible, interoperable infrastructure for bidirectional communications capable of integrating public health knowledge into clinical systems and workflows. PMID:23467470

  14. Using experience with bidirectional HL7-ACR-NEMA interfaces between the federal government HIS/RIS and commercial PACS to plan for DICOM

    NASA Astrophysics Data System (ADS)

    Kuzmak, Peter M.; Norton, Gary S.; Dayhoff, Ruth E.

    1995-05-01

    The Department of Veterans Affairs has developed a bidirectional HL7 - ACR-NEMA V 2.0 interface for connecting existing federal government hospital/radiology information systems (HIS/RIS) to commercial picture archive and communication systems (PACS). The interface has been in use since October 1993 at the Baltimore VAMC between the VA's HIS/RIS (DHCP) and a commercial PACS, and handles both text and image transfer. The text-only portion of the interface has been ported to work with a second vendor's PACS, and to work with the Department of Defense HIS/RIS (CHCS). Currently the interface is in production at two VA and three DoD sites. The common benefit experienced at all these sites is that passing patient, order, and report information directly from the HIS/RIS to the PACS greatly improves the flow of work in the Radiology Department. Image transfer to the DHCP Imaging System at the Baltimore VAMC demonstrated the advantage of providing `reference quality' (1K X 1K X 8-bit) radiology images to treating clinicians throughout the hospital. Experience has shown that the gateway must handle transactions between the HIS/RIS and the PACS quickly in order to keep up with the volume, and must provide an audit trail for system diagnostic purposes. Work is underway to construct a HL7 - DICOM gateway built upon the operational experience gathered from the existing interface.

  15. Low-power integrated-circuit driver for ferrite-memory word lines

    NASA Technical Reports Server (NTRS)

    Katz, S.

    1970-01-01

    Composite circuit uses both n-p-n bipolar and p-channel MOS transistors /BIMOS/. The BIMOS driver provides 1/ ease of integrated circuit construction, 2/ low standby power consumption, 3/ bidirectional current pulses, and 4/ current-pulse amplitudes and rise times independent of active device parameters.

  16. Observations of a bi-directional lightning leader producing an M-component

    NASA Astrophysics Data System (ADS)

    Kotovsky, D. A.; Uman, M. A.; Wilkes, R.; Carvalho, F. L.; Jordan, D. M.

    2017-12-01

    Lightning discharges to ground often exhibit millisecond-scale surges in the continuing currents following return strokes, called M-components. Relatively little is known regarding the source of M-component charge and the mechanisms by which that charge is transferred to ground. In this work, we seek to directly address these questions by presenting correlated high-speed video and Lightning Mapping Array (LMA) observations of a bi-directional leader that resulted in an M-component occurring in a rocket-and-wire triggered lightning flash. The observed leader initiated in the decayed remnants of a positive leader channel that had traversed virgin air approximately 90 msec prior. Three-dimensional locations and speeds of the photographed bi-directional leader and M-component processes are calculated by mapping video images to the observed LMA channel geometry. Both ends of the bi-directional leader exhibited speeds on the order of 2 x106 m sec-1 over 570 meters of the visible channel. Propagation of the luminosity wave from the in-cloud leader to ground ( 8.8 km channel length) exhibited appreciable dispersion, with rise-times (10-90%) increasing from 330 to 410 μsec and pulse-widths (half-maximum) increasing from 380 to 810 μsec - the M-component current pulse measured at ground-level exhibited a rise-time of 290 μsec and a pulse-width of 770 μsec. Group velocities of the luminosity wave have been calculated as a function of frequency, increasing from 2 x107 to 6 x107 m sec-1 over the dominant signal bandwidth (DC to 2 kHz). Additionally, multiple waves of luminosity are observed within the in-cloud channel, indicating nuanced wave phenomena possibly associated with reflection from the end of the leader channel and attachment with the main lightning channel carrying continuing current to ground.

  17. Investigation of Voronoi diagram based direction choices using uni- and bi-directional trajectory data

    NASA Astrophysics Data System (ADS)

    Xiao, Yao; Chraibi, Mohcine; Qu, Yunchao; Tordeux, Antoine; Gao, Ziyou

    2018-05-01

    In a crowd, individuals make different motion choices such as "moving to destination," "following another pedestrian," and "making a detour." For the sake of convenience, the three direction choices are respectively called destination direction, following direction, and detour direction in this paper. Here, it is found that the featured direction choices could be inspired by the shape characteristics of the Voronoi diagram. To be specific, in the Voronoi cell of a pedestrian, the direction to a Voronoi node is regarded as a potential "detour" direction and the direction perpendicular to a Voronoi link is regarded as a potential "following" direction. A pedestrian generally owns several alternative Voronoi nodes and Voronoi links in a Voronoi cell, and the optimal detour and following direction are determined by considering related factors such as deviation. Plus the destination direction which is directly pointing to the destination, the three basic direction choices are defined in a Voronoi cell. In order to evaluate the Voronoi diagram based basic directions, the empirical trajectory data in both uni- and bi-directional flow experiments are extracted. A time series method considering the step frequency is used to reduce the original trajectories' swaying phenomena which might disturb the recognition of actual forward direction. The deviations between the empirical velocity direction and the basic directions are investigated, and each velocity direction is classified into a basic direction or regarded as an inexplicable direction according to the deviations. The analysis results show that each basic direction could be a potential direction choice for a pedestrian. The combination of the three basic directions could cover most empirical velocity direction choices in both uni- and bi-directional flow experiments.

  18. 77 FR 1674 - Tennessee Gas Pipeline Company, L.L.C.; Notice of Intent To Prepare an Environmental Assessment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ... stations to provide bi-directional natural gas flow: a. Station 219, in Mercer County; b. Station 303, in Venango County; c. Station 310, in McKean County; and d. Station 313, in Potter County. The general... yards, compressor stations, and access roads). Our EA for this project will document our findings on the...

  19. PWM Inverter with Voltage Boosters with Regenerating Capability Augmented by Electric Double-Layer Capacitor

    NASA Astrophysics Data System (ADS)

    Yamamoto, Kichiro; Imakiire, Akihiro; Iimori, Kenichi

    An interior permanent magnet (IPM) motor drive system which has regenerating capability augmented by electric double-layer capacitors (EDLCs) is proposed. In the proposed system, EDLCs are arranged in series with batteries so that a lesser number of the EDLCs and batteries will be required. The proposed system has two bi-directional voltage boosters: one is for both the batteries and EDLCs to control the dc-link voltage of a PWM inverter and the other is for only the EDLCs and is used to control the energy flow from and to the EDLCs. In this paper, a strategy to control the energy flow to and from the EDLCs is explained and its effectiveness is confirmed by simulation and experimental results. Furthermore, the efficiencies of the voltage booster, inverter, PM motor, and whole system are measured for the system with the basic configuration, i.e., which consists of only one bi-directional voltage booster and PWM inverter. Then, the steady-state characteristics are determined. Finally, the efficiency of the voltage boosters in the proposed system is determined, and the advantage of the proposed PM motor drive system is discussed.

  20. Bidirectional buck boost converter

    DOEpatents

    Esser, Albert Andreas Maria

    1998-03-31

    A bidirectional buck boost converter and method of operating the same allows regulation of power flow between first and second voltage sources in which the voltage level at each source is subject to change and power flow is independent of relative voltage levels. In one embodiment, the converter is designed for hard switching while another embodiment implements soft switching of the switching devices. In both embodiments, first and second switching devices are serially coupled between a relatively positive terminal and a relatively negative terminal of a first voltage source with third and fourth switching devices serially coupled between a relatively positive terminal and a relatively negative terminal of a second voltage source. A free-wheeling diode is coupled, respectively, in parallel opposition with respective ones of the switching devices. An inductor is coupled between a junction of the first and second switching devices and a junction of the third and fourth switching devices. Gating pulses supplied by a gating circuit selectively enable operation of the switching devices for transferring power between the voltage sources. In the second embodiment, each switching device is shunted by a capacitor and the switching devices are operated when voltage across the device is substantially zero.

  1. Bidirectional buck boost converter

    DOEpatents

    Esser, A.A.M.

    1998-03-31

    A bidirectional buck boost converter and method of operating the same allows regulation of power flow between first and second voltage sources in which the voltage level at each source is subject to change and power flow is independent of relative voltage levels. In one embodiment, the converter is designed for hard switching while another embodiment implements soft switching of the switching devices. In both embodiments, first and second switching devices are serially coupled between a relatively positive terminal and a relatively negative terminal of a first voltage source with third and fourth switching devices serially coupled between a relatively positive terminal and a relatively negative terminal of a second voltage source. A free-wheeling diode is coupled, respectively, in parallel opposition with respective ones of the switching devices. An inductor is coupled between a junction of the first and second switching devices and a junction of the third and fourth switching devices. Gating pulses supplied by a gating circuit selectively enable operation of the switching devices for transferring power between the voltage sources. In the second embodiment, each switching device is shunted by a capacitor and the switching devices are operated when voltage across the device is substantially zero. 20 figs.

  2. Single phase bi-directional AC-DC converter with reduced passive components size and common mode electro-magnetic interference

    DOEpatents

    Mi, Chris; Li, Siqi

    2017-01-31

    A bidirectional AC-DC converter is presented with reduced passive component size and common mode electro-magnetic interference. The converter includes an improved input stage formed by two coupled differential inductors, two coupled common and differential inductors, one differential capacitor and two common mode capacitors. With this input structure, the volume, weight and cost of the input stage can be reduced greatly. Additionally, the input current ripple and common mode electro-magnetic interference can be greatly attenuated, so lower switching frequency can be adopted to achieve higher efficiency.

  3. Magnetic reconnection process in transient coaxial helicity injection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ebrahimi, F.; Hooper, E. B.; Sovinec, C. R.

    The physics of magnetic reconnection and fast flux closure in transient coaxial helicity injection experiments in NSTX is examined using resistive MHD simulations. These simulations have been performed using the NIMROD code with fixed boundary flux (including NSTX poloidal coil currents) in the NSTX experimental geometry. Simulations show that an X point is formed in the injector region, followed by formation of closed flux surfaces within 0.5 ms after the driven injector voltage and injector current begin to rapidly decrease. As the injector voltage is turned off, the field lines tend to untwist in the toroidal direction and magnetic fieldmore » compression exerts a radial J × B force and generates a bi-directional radial E{sub toroidal}×B{sub poloidal} pinch flow to bring oppositely directed field lines closer together to reconnect. At sufficiently low magnetic diffusivity (high Lundquist number), and with a sufficiently narrow injector flux footprint width, the oppositely directed field lines have sufficient time to reconnect (before dissipating), leading to the formation of closed flux surfaces. The reconnection process is shown to have transient Sweet-Parker characteristics.« less

  4. Non-Darcy flow of water-based carbon nanotubes with nonlinear radiation and heat generation/absorption

    NASA Astrophysics Data System (ADS)

    Hayat, T.; Ullah, Siraj; Khan, M. Ijaz; Alsaedi, A.; Zaigham Zia, Q. M.

    2018-03-01

    Here modeling and computations are presented to introduce the novel concept of Darcy-Forchheimer three-dimensional flow of water-based carbon nanotubes with nonlinear thermal radiation and heat generation/absorption. Bidirectional stretching surface induces the flow. Darcy's law is commonly replace by Forchheimer relation. Xue model is implemented for nonliquid transport mechanism. Nonlinear formulation based upon conservation laws of mass, momentum and energy is first modeled and then solved by optimal homotopy analysis technique. Optimal estimations of auxiliary variables are obtained. Importance of influential variables on the velocity and thermal fields is interpreted graphically. Moreover velocity and temperature gradients are discussed and analyzed. Physical interpretation of influential variables is examined.

  5. Tidal energy site resource assessment in the East River tidal strait, near Roosevelt Island, New York, New York

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gunawan, Budi; Neary, Vincent S.; Colby, Jonathan

    This study demonstrates a site resource assessment to examine the temporal variation of the mean current, turbulence intensities, and power densities for a tidal energy site in the East River tidal strait. These variables were derived from two-months of acoustic Doppler velocimeter (ADV) measurements at the design hub height of the Verdant Power Gen5 hydrokinetic turbine. The study site is a tidal strait that exhibits semi-diurnal tidal current characteristics, with a mean horizontal current speed of 1.4 m s -1, and turbulence intensity of 15% at a reference mean current of 2 m s -1. Flood and ebb flow directionsmore » are nearly bi-directional, with higher current magnitude during flood tide, which skews the power production towards the flood tide period. The tidal hydrodynamics at the site are highly regular, as indicated by the tidal current time series that resembles a sinusoidal function. This study also shows that the theoretical force and power densities derived from the current measurements can significantly be influenced by the length of the time window used for averaging the current data. Furthermore, the theoretical power density at the site, derived from the current measurements, is one order of magnitude greater than that reported in the U.S. national resource assessment. As a result, this discrepancy highlights the importance of conducting site resource assessments based on measurements at the tidal energy converter device scale.« less

  6. Tidal energy site resource assessment in the East River tidal strait, near Roosevelt Island, New York, New York

    DOE PAGES

    Gunawan, Budi; Neary, Vincent S.; Colby, Jonathan

    2014-06-22

    This study demonstrates a site resource assessment to examine the temporal variation of the mean current, turbulence intensities, and power densities for a tidal energy site in the East River tidal strait. These variables were derived from two-months of acoustic Doppler velocimeter (ADV) measurements at the design hub height of the Verdant Power Gen5 hydrokinetic turbine. The study site is a tidal strait that exhibits semi-diurnal tidal current characteristics, with a mean horizontal current speed of 1.4 m s -1, and turbulence intensity of 15% at a reference mean current of 2 m s -1. Flood and ebb flow directionsmore » are nearly bi-directional, with higher current magnitude during flood tide, which skews the power production towards the flood tide period. The tidal hydrodynamics at the site are highly regular, as indicated by the tidal current time series that resembles a sinusoidal function. This study also shows that the theoretical force and power densities derived from the current measurements can significantly be influenced by the length of the time window used for averaging the current data. Furthermore, the theoretical power density at the site, derived from the current measurements, is one order of magnitude greater than that reported in the U.S. national resource assessment. As a result, this discrepancy highlights the importance of conducting site resource assessments based on measurements at the tidal energy converter device scale.« less

  7. Bidirectional Telemetry Controller for Neuroprosthetic Devices

    PubMed Central

    Sharma, Vishnu; McCreery, Douglas B.; Han, Martin; Pikov, Victor

    2010-01-01

    We present versatile multifunctional programmable controller with bidirectional data telemetry, implemented using existing commercial microchips and standard Bluetooth protocol, which adds convenience, reliability, and ease-of-use to neuroprosthetic devices. Controller, weighing 190 g, is placed on animal's back and provides bidirectional sustained telemetry rate of 500 kb/s, allowing real-time control of stimulation parameters and viewing of acquired data. In continuously-active state, controller consumes ∼420 mW and operates without recharge for 8 h. It features independent 16-channel current-controlled stimulation, allowing current steering; customizable stimulus current waveforms; recording of stimulus voltage waveforms and evoked neuronal responses with stimulus artifact blanking circuitry. Flexibility, scalability, cost-efficiency, and a user-friendly computer interface of this device allow use in animal testing for variety of neuroprosthetic applications. Initial testing of the controller has been done in a feline model of brainstem auditory prosthesis. In this model, the electrical stimulation is applied to the array of microelectrodes implanted in the ventral cochlear nucleus, while the evoked neuronal activity was recorded with the electrode implanted in the contralateral inferior colliculus. Stimulus voltage waveforms to monitor the access impedance of the electrodes were acquired at the rate of 312 kilosamples/s. Evoked neuronal activity in the inferior colliculus was recorded after the blanking (transient silencing) of the recording amplifier during the stimulus pulse, allowing the detection of neuronal responses within 100 μs after the end of the stimulus pulse applied in the cochlear nucleus. PMID:19933010

  8. Electromigration failures under bidirectional current stress

    NASA Astrophysics Data System (ADS)

    Tao, Jiang; Cheung, Nathan W.; Hu, Chenming

    1998-01-01

    Electromigration failure under DC stress has been studied for more than 30 years, and the methodologies for accelerated DC testing and design rules have been well established in the IC industry. However, the electromigration behavior and design rules under time-varying current stress are still unclear. In CMOS circuits, as many interconnects carry pulsed-DC (local VCC and VSS lines) and bidirectional AC current (clock and signal lines), it is essential to assess the reliability of metallization systems under these conditions. Failure mechanisms of different metallization systems (Al-Si, Al-Cu, Cu, TiN/Al-alloy/TiN, etc.) and different metallization structures (via, plug and interconnect) under AC current stress in a wide frequency range (from mHz to 500 MHz) has been study in this paper. Based on these experimental results, a damage healing model is developed, and electromigration design rules are proposed. It shows that in the circuit operating frequency range, the "design-rule current" is the time-average current. The pure AC component of the current only contributes to self-heating, while the average (DC component) current contributes to electromigration. To ensure longer thermal-migration lifetime under high frequency AC stress, an additional design rule is proposed to limit the temperature rise due to self-joule heating.

  9. A solid-state controllable power supply for a magnetic suspension wind tunnel

    NASA Technical Reports Server (NTRS)

    Daniels, Taumi S.; Tripp, John S.

    1991-01-01

    The NASA Langley 6-inch Magnetic Suspension and Balance System (6-in. MSBS) requires an independently controlled bidirectional dc power source for each of six positioning electromagnets. These electromagnets provide five-degree-of-freedom control over a suspended aerodynamic test model. Existing power equipment, which employs resistance-coupled thyratron-controlled rectifiers as well as ac to dc motor-generator converters, is obsolete, inefficient, and unreliable. A replacement six-phase bidirectional controlled bridge rectifier is proposed, which employs power MOSFET switches sequenced by hybrid analog/digital circuits. Full-load efficiency is 80 percent compared with 25 percent for the resistance-coupled thyratron system. Current feedback provides high control linearity, adjustable current limiting, and current overload protection. A quenching circuit suppresses inductive voltage impulses. It is shown that 20-kHz interference from positioning magnet power into MSBS electromagnetic model position sensors results predominantly from capacitively coupled electric fields. Hence, proper shielding and grounding techniques are necessary. Inductively coupled magnetic interference is negligible.

  10. Measurement of characteristic parameters of 10 Gb/s bidirectional optical amplifier for XG-PON

    NASA Astrophysics Data System (ADS)

    Rakkammee, Suchaj; Boriboon, Budsara; Worasucheep, Duang-rudee; Wada, Naoya

    2018-03-01

    This research experimentally measured the characteristic parameters of 10 Gb/s bidirectional optical amplifier: (1) operating wavelength range, (2) small signal gain, (3) Polarization Dependent Loss (PDL), and (4) power consumption. Bidirectional amplifiers are the key component to extend coverage area as well as increase a number of users in Passive Optical Networks (PON). According to 10-Gigabit-capable PON or XG-PON standard, the downstream and upstream wavelengths are 1577 nm and 1270 nm respectively. Thus, our bidirectional amplifier consists of an Erbium Doped Fiber Amplifier (EDFA) and a Semiconductor Optical Amplifier (SOA) for downstream and upstream wavelength transmissions respectively. The operating wavelengths of EDFA and SOA are measured to be from 1570 nm to 1588 nm and 1263 nm to 1280 nm respectively. To measure gain, the input wavelengths of EDFA and SOA were fixed at 1577 nm and 1271 nm respectively, while their input powers were reduced by a variable optical attenuator. The small signal gain of EDFA is 22.5 dB at 0.15 Ampere pump current, whereas the small signal gain of SOA is 7.06 dB at 0.325 Ampere pump current. To measure PDL, which is a difference in output powers at various State of Polarization (SoP) of input signal, a polarization controller was inserted before amplifier to alter input SoP. The measured PDL of EDFA is insignificant with less than 0.1 dB. In contrast, the measured PDL of SOA is as large as 33 dB, indicating its strong polarization dependence. The total power consumptions were measured to be 1.5675 Watt.

  11. Orbital atherectomy for the treatment of severely calcified coronary lesions: evidence, technique, and best practices.

    PubMed

    Shlofmitz, Evan; Martinsen, Brad J; Lee, Michael; Rao, Sunil V; Généreux, Philippe; Higgins, Joe; Chambers, Jeffrey W; Kirtane, Ajay J; Brilakis, Emmanouil S; Kandzari, David E; Sharma, Samin K; Shlofmitz, Richard

    2017-11-01

    The presence of severe coronary artery calcification is associated with higher rates of angiographic complications during percutaneous coronary intervention (PCI), as well as higher major adverse cardiac events compared with non-calcified lesions. Incorporating orbital atherectomy (OAS) for effective preparation of severely calcified lesions can help maximize the benefits of PCI by attaining maximal luminal gain (or stent expansion) and improve long-term outcomes (by reducing need for revascularization). Areas covered: In this manuscript, the prevalence, risk factors, and impact of coronary artery calcification on PCI are reviewed. Based on current data and experience, the authors review orbital atherectomy technique and best practices to optimize lesion preparation. Expert Commentary: The coronary OAS is the only device approved for use in the U.S. as a treatment for de novo, severely calcified coronary lesions to facilitate stent delivery. Advantages of the device include its ease of use and a mechanism of action that treats bi-directionally, allowing for continuous blood flow during treatment, minimizing heat damage, slow flow, and subsequent need for revascularization. The OAS technique tips reviewed in this article will help inform interventional cardiologists treating patients with severely calcified lesions.

  12. Achieving Bidirectional Long Delays In Pulmonary Vein Antral Lines Prior To Bidirectional Block In Patients With Paroxysmal Atrial Fibrillation (The Bi-Bi Technique For Atrial Fibrillation Ablation).

    PubMed

    Mina, Adel F; Warnecke, Nicholas L

    2016-01-01

    Background: Pulmonary Vein Antral isolation (PVAI) is currently the standard of care for both paroxysmal and persistent atrial fibrillation ablation. Reconnection to the pulmonary vein is the most common cause of recurrence of atrial fibrillation. Achieving the endpoint of bidirectional block (BDB) for cavotricuspid isthmus dependant flutter has improved our outcomes for atrial flutter ablation. With this we tried to achieve long delays in the pulmonary veins antral lines prior to complete isolation comparable to those delays found in patient with bidirectional block of atrial flutter lines. Study Objective: The objective of this paper was to evaluate feasibility and efficacy of achieving Bidirectional long delays in pulmonary vein antral lines prior to Bidirectional Block in patient with paroxysmal atrial fibrillation. Method: A retrospective analysis was performed on patients who had paroxysmal atrial fibrillation procedures at Unity Point Methodist from January 2015 to January 2016. 20 consecutive patients with paroxysmal atrial fibrillation who had AF ablation using the Bi-Bi technique were evaluated. Result: Mean age was 63, number of antiarrhythmic used prior to ablation was 1.4, mean left atrial size was 38 mm. Mean chads score was 1.3. Mean EF was 53%. Long delays in the left antral circumferential lines were achieved with mean delay of 142 milliseconds +/-100. Also long delays in the right antral circumferential lines were achieved with mean delay of 150 milliseconds +/-80. 95 % (19/20) of patients were free of any atrial arrhythmias and were off antiarrhythmic medications for AF post procedure. There was only one transient complication in one patient who developed a moderate pericardial effusion that was successfully drained with no hemodynamic changes. The only patient who had recurrence was found to have asymptomatic AF with burden on his device <1%, this patient was also found to have non PV triggers for his AF. In patients with only PV triggered AF success rate was 100%. Conclusion: Achievement of Bidirectional long delays in pulmonary vein antral lines prior to Bidirectional Block in patient with paroxysmal atrial fibrillation is feasible and highly effective technique in this small cohort of patients studied. We also outlined the procedure in details.

  13. Megacrystals track magma convection between reservoir and surface

    NASA Astrophysics Data System (ADS)

    Moussallam, Yves; Oppenheimer, Clive; Scaillet, Bruno; Buisman, Iris; Kimball, Christine; Dunbar, Nelia; Burgisser, Alain; Ian Schipper, C.; Andújar, Joan; Kyle, Philip

    2015-03-01

    Active volcanoes are typically fed by magmatic reservoirs situated within the upper crust. The development of thermal and/or compositional gradients in such magma chambers may lead to vigorous convection as inferred from theoretical models and evidence for magma mixing recorded in volcanic rocks. Bi-directional flow is also inferred to prevail in the conduits of numerous persistently-active volcanoes based on observed gas and thermal emissions at the surface, as well as experiments with analogue models. However, more direct evidence for such exchange flows has hitherto been lacking. Here, we analyse the remarkable oscillatory zoning of anorthoclase feldspar megacrystals erupted from the lava lake of Erebus volcano, Antarctica. A comprehensive approach, combining phase equilibria, solubility experiments and melt inclusion and textural analyses shows that the chemical profiles are best explained as a result of multiple episodes of magma transport between a deeper reservoir and the lava lake at the surface. Individual crystals have repeatedly travelled up-and-down the plumbing system, over distances of up to several kilometers, presumably as a consequence of entrainment in the bulk magma flow. Our findings thus corroborate the model of bi-directional flow in magmatic conduits. They also imply contrasting flow regimes in reservoir and conduit, with vigorous convection in the former (regular convective cycles of ∼150 days at a speed of ∼0.5 mm s-1) and more complex cycles of exchange flow and re-entrainment in the latter. We estimate that typical, 1-cm-wide crystals should be at least 14 years old, and can record several (from 1 to 3) complete cycles between the reservoir and the lava lake via the conduit. This persistent recycling of phonolitic magma is likely sustained by CO2 fluxing, suggesting that accumulation of mafic magma in the lower crust is volumetrically more significant than that of evolved magma within the edifice.

  14. Reciprocating magnetic refrigerator employing tandem porous matrices within a reciprocating displacer

    NASA Technical Reports Server (NTRS)

    Johnson, D. L. (Inventor)

    1985-01-01

    Disclosed is a method and apparatus for a magnetic refrigeration system. A continuously reciprocating displacer houses at least a pair of paramagnetic substances each of which is alternately driven into and out of a magnetic field. Two separate bidirectional pumping systems flow helium gas through the displacer and through both paramagnetic substances to create heat exchange conditions at two separate temperature extremes.

  15. Dissertation Leadership Knowledge Transfer Using Sparsely Connected Networks with Bidirectional Edges: Case Study of Chester Hayden McCall Jr., His Dissertation Advisors, and His Students

    ERIC Educational Resources Information Center

    Mallette, Leo A.

    2012-01-01

    There are many modes of information flow in the sciences: books, journals, conferences, research and development, acquisition of companies, co-workers, students, and professors in schools of higher learning. In the sciences, dissertation students learn from their dissertation advisor (or chairperson or mentor) and the other dissertation committee…

  16. Brain signal variability as a window into the bidirectionality between music and language processing: moving from a linear to a nonlinear model

    PubMed Central

    Hutka, Stefanie; Bidelman, Gavin M.; Moreno, Sylvain

    2013-01-01

    There is convincing empirical evidence for bidirectional transfer between music and language, such that experience in either domain can improve mental processes required by the other. This music-language relationship has been studied using linear models (e.g., comparing mean neural activity) that conceptualize brain activity as a static entity. The linear approach limits how we can understand the brain’s processing of music and language because the brain is a nonlinear system. Furthermore, there is evidence that the networks supporting music and language processing interact in a nonlinear manner. We therefore posit that the neural processing and transfer between the domains of language and music are best viewed through the lens of a nonlinear framework. Nonlinear analysis of neurophysiological activity may yield new insight into the commonalities, differences, and bidirectionality between these two cognitive domains not measurable in the local output of a cortical patch. We thus propose a novel application of brain signal variability (BSV) analysis, based on mutual information and signal entropy, to better understand the bidirectionality of music-to-language transfer in the context of a nonlinear framework. This approach will extend current methods by offering a nuanced, network-level understanding of the brain complexity involved in music-language transfer. PMID:24454295

  17. Brain signal variability as a window into the bidirectionality between music and language processing: moving from a linear to a nonlinear model.

    PubMed

    Hutka, Stefanie; Bidelman, Gavin M; Moreno, Sylvain

    2013-12-30

    There is convincing empirical evidence for bidirectional transfer between music and language, such that experience in either domain can improve mental processes required by the other. This music-language relationship has been studied using linear models (e.g., comparing mean neural activity) that conceptualize brain activity as a static entity. The linear approach limits how we can understand the brain's processing of music and language because the brain is a nonlinear system. Furthermore, there is evidence that the networks supporting music and language processing interact in a nonlinear manner. We therefore posit that the neural processing and transfer between the domains of language and music are best viewed through the lens of a nonlinear framework. Nonlinear analysis of neurophysiological activity may yield new insight into the commonalities, differences, and bidirectionality between these two cognitive domains not measurable in the local output of a cortical patch. We thus propose a novel application of brain signal variability (BSV) analysis, based on mutual information and signal entropy, to better understand the bidirectionality of music-to-language transfer in the context of a nonlinear framework. This approach will extend current methods by offering a nuanced, network-level understanding of the brain complexity involved in music-language transfer.

  18. Bidirectional Hebbian Plasticity Induced by Low-Frequency Stimulation in Basal Dendrites of Rat Barrel Cortex Layer 5 Pyramidal Neurons.

    PubMed

    Díez-García, Andrea; Barros-Zulaica, Natali; Núñez, Ángel; Buño, Washington; Fernández de Sevilla, David

    2017-01-01

    According to Hebb's original hypothesis (Hebb, 1949), synapses are reinforced when presynaptic activity triggers postsynaptic firing, resulting in long-term potentiation (LTP) of synaptic efficacy. Long-term depression (LTD) is a use-dependent decrease in synaptic strength that is thought to be due to synaptic input causing a weak postsynaptic effect. Although the mechanisms that mediate long-term synaptic plasticity have been investigated for at least three decades not all question have as yet been answered. Therefore, we aimed at determining the mechanisms that generate LTP or LTD with the simplest possible protocol. Low-frequency stimulation of basal dendrite inputs in Layer 5 pyramidal neurons of the rat barrel cortex induces LTP. This stimulation triggered an EPSP, an action potential (AP) burst, and a Ca 2+ spike. The same stimulation induced LTD following manipulations that reduced the Ca 2+ spike and Ca 2+ signal or the AP burst. Low-frequency whisker deflections induced similar bidirectional plasticity of action potential evoked responses in anesthetized rats. These results suggest that both in vitro and in vivo similar mechanisms regulate the balance between LTP and LTD. This simple induction form of bidirectional hebbian plasticity could be present in the natural conditions to regulate the detection, flow, and storage of sensorimotor information.

  19. Bidirectional Hebbian Plasticity Induced by Low-Frequency Stimulation in Basal Dendrites of Rat Barrel Cortex Layer 5 Pyramidal Neurons

    PubMed Central

    Díez-García, Andrea; Barros-Zulaica, Natali; Núñez, Ángel; Buño, Washington; Fernández de Sevilla, David

    2017-01-01

    According to Hebb's original hypothesis (Hebb, 1949), synapses are reinforced when presynaptic activity triggers postsynaptic firing, resulting in long-term potentiation (LTP) of synaptic efficacy. Long-term depression (LTD) is a use-dependent decrease in synaptic strength that is thought to be due to synaptic input causing a weak postsynaptic effect. Although the mechanisms that mediate long-term synaptic plasticity have been investigated for at least three decades not all question have as yet been answered. Therefore, we aimed at determining the mechanisms that generate LTP or LTD with the simplest possible protocol. Low-frequency stimulation of basal dendrite inputs in Layer 5 pyramidal neurons of the rat barrel cortex induces LTP. This stimulation triggered an EPSP, an action potential (AP) burst, and a Ca2+ spike. The same stimulation induced LTD following manipulations that reduced the Ca2+ spike and Ca2+ signal or the AP burst. Low-frequency whisker deflections induced similar bidirectional plasticity of action potential evoked responses in anesthetized rats. These results suggest that both in vitro and in vivo similar mechanisms regulate the balance between LTP and LTD. This simple induction form of bidirectional hebbian plasticity could be present in the natural conditions to regulate the detection, flow, and storage of sensorimotor information. PMID:28203145

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aeloiza, Eddy C.; Burgos, Rolando P.

    A step-down AC/AC converter for use in an electric distribution system includes at least one chopper circuit for each one of a plurality of phases of the AC power, each chopper circuit including a four-quadrant switch coupled in series between primary and secondary sides of the chopper circuit and a current-bidirectional two-quadrant switch coupled between the secondary side of the chopper circuit and a common node. Each current-bidirectional two-quadrant switch is oriented in the same direction, with respect to the secondary side of the corresponding chopper circuit and the common node. The converter further includes a control circuit configured tomore » pulse-width-modulate control inputs of the switches, to convert a first multiphase AC voltage at the primary sides of the chopper circuits to a second multiphase AC voltage at the secondary sides of the chopper circuits, the second multiphase AC voltage being lower in voltage than the first multiphase AC voltage.« less

  1. Discharge estimation from H-ADCP measurements in a tidal river subject to sidewall effects and a mobile bed

    NASA Astrophysics Data System (ADS)

    Sassi, M. G.; Hoitink, A. J. F.; Vermeulen, B.; Hidayat, null

    2011-06-01

    Horizontal acoustic Doppler current profilers (H-ADCPs) can be employed to estimate river discharge based on water level measurements and flow velocity array data across a river transect. A new method is presented that accounts for the dip in velocity near the water surface, which is caused by sidewall effects that decrease with the width to depth ratio of a channel. A boundary layer model is introduced to convert single-depth velocity data from the H-ADCP to specific discharge. The parameters of the model include the local roughness length and a dip correction factor, which accounts for the sidewall effects. A regression model is employed to translate specific discharge to total discharge. The method was tested in the River Mahakam, representing a large river of complex bathymetry, where part of the flow is intrinsically three-dimensional and discharge rates exceed 8000 m3 s-1. Results from five moving boat ADCP campaigns covering separate semidiurnal tidal cycles are presented, three of which are used for calibration purposes, whereas the remaining two served for validation of the method. The dip correction factor showed a significant correlation with distance to the wall and bears a strong relation to secondary currents. The sidewall effects appeared to remain relatively constant throughout the tidal cycles under study. Bed roughness length is estimated at periods of maximum velocity, showing more variation at subtidal than at intratidal time scales. Intratidal variations were particularly obvious during bidirectional flow conditions, which occurred only during conditions of low river discharge. The new method was shown to outperform the widely used index velocity method by systematically reducing the relative error in the discharge estimates.

  2. Self-organized phenomena of pedestrian counterflow through a wide bottleneck in a channel

    NASA Astrophysics Data System (ADS)

    Dong, Li-Yun; Lan, Dong-Kai; Li, Xiang

    2016-09-01

    The pedestrian counterflow through a bottleneck in a channel shows a variety of flow patterns due to self-organization. In order to reveal the underlying mechanism, a cellular automaton model was proposed by incorporating the floor field and the view field which reflects the global information of the studied area and local interactions with others. The presented model can well reproduce typical collective behaviors, such as lane formation. Numerical simulations were performed in the case of a wide bottleneck and typical flow patterns at different density ranges were identified as rarefied flow, laminar flow, interrupted bidirectional flow, oscillatory flow, intermittent flow, and choked flow. The effects of several parameters, such as the size of view field and the width of opening, on the bottleneck flow are also analyzed in detail. The view field plays a vital role in reproducing self-organized phenomena of pedestrian. Numerical results showed that the presented model can capture key characteristics of bottleneck flows. Project supported by the National Basic Research Program of China (Grant No. 2012CB725404) and the National Natural Science Foundation of China (Grant Nos. 11172164 and 11572184).

  3. Shape Optimization of the Assisted Bi-directional Glenn surgery for stage-1 single ventricle palliation

    NASA Astrophysics Data System (ADS)

    Verma, Aekaansh; Shang, Jessica; Esmaily-Moghadam, Mahdi; Wong, Kwai; Marsden, Alison

    2016-11-01

    Babies born with a single functional ventricle typically undergo three open-heart surgeries starting as neonates. The first of these stages (BT shunt or Norwood) has the highest mortality rates of the three, approaching 30%. Proceeding directly to a stage-2 Glenn surgery has historically demonstrated inadequate pulmonary flow (PF) & high mortality. Recently, the Assisted Bi-directional Glenn (ABG) was proposed as a promising means to achieve a stable physiology by assisting the PF via an 'ejector pump' from the systemic circulation. We present preliminary parametrization and optimization results for the ABG geometry, with the goal of increasing PF. To limit excessive pressure increases in the Superior Vena Cava (SVC), the SVC pressure is included as a constraint. We use 3-D finite element flow simulations coupled with a single ventricle lumped parameter network to evaluate PF & the pressure constraint. We employ a derivative free optimization method- the Surrogate Management Framework, in conjunction with the OpenDIEL framework to simulate multiple simultaneous evaluations. Results show that nozzle diameter is the most important design parameter affecting ABG performance. The application of these results to patient specific situations will be discussed. This work was supported by an NSF CAREER award (OCI1150184) and by the XSEDE National Computing Resource.

  4. On Multiple AER Handshaking Channels Over High-Speed Bit-Serial Bidirectional LVDS Links With Flow-Control and Clock-Correction on Commercial FPGAs for Scalable Neuromorphic Systems.

    PubMed

    Yousefzadeh, Amirreza; Jablonski, Miroslaw; Iakymchuk, Taras; Linares-Barranco, Alejandro; Rosado, Alfredo; Plana, Luis A; Temple, Steve; Serrano-Gotarredona, Teresa; Furber, Steve B; Linares-Barranco, Bernabe

    2017-10-01

    Address event representation (AER) is a widely employed asynchronous technique for interchanging "neural spikes" between different hardware elements in neuromorphic systems. Each neuron or cell in a chip or a system is assigned an address (or ID), which is typically communicated through a high-speed digital bus, thus time-multiplexing a high number of neural connections. Conventional AER links use parallel physical wires together with a pair of handshaking signals (request and acknowledge). In this paper, we present a fully serial implementation using bidirectional SATA connectors with a pair of low-voltage differential signaling (LVDS) wires for each direction. The proposed implementation can multiplex a number of conventional parallel AER links for each physical LVDS connection. It uses flow control, clock correction, and byte alignment techniques to transmit 32-bit address events reliably over multiplexed serial connections. The setup has been tested using commercial Spartan6 FPGAs attaining a maximum event transmission speed of 75 Meps (Mega events per second) for 32-bit events at a line rate of 3.0 Gbps. Full HDL codes (vhdl/verilog) and example demonstration codes for the SpiNNaker platform will be made available.

  5. They can interact, but can they learn? Toddlers' transfer learning from touchscreens and television.

    PubMed

    Moser, Alecia; Zimmermann, Laura; Dickerson, Kelly; Grenell, Amanda; Barr, Rachel; Gerhardstein, Peter

    2015-09-01

    Despite the ubiquity of touchscreen applications and television programs for young children, developmental research suggests that learning in this context is degraded relative to face-to-face interactions. Most previous research has been limited to transfer of learning from videos, making it difficult to isolate the relative perceptual and social influences for transfer difficulty, and has not examined whether the transfer deficit persists across early childhood when task complexity increases. The current study examined whether the transfer deficit persists in older children using a complex puzzle imitation task constructed to investigate transfer from video demonstrations. The current test adapted this task to permit bidirectional transfer from touchscreens as well. To test for bidirectional transfer deficits, 2.5- and 3-year-olds were shown how to assemble a three-piece puzzle on either a three-dimensional magnetic board or a two-dimensional touchscreen (Experiment 1). Unidirectional transfer from video was also tested (Experiment 2). Results indicate that a bidirectional transfer deficit persists through 3 years, with younger children showing a greater transfer deficit; despite high perceptual similarities and social engagement, children learned less in transfer tasks, supporting the memory flexibility account of the transfer deficit. Implications of these findings for use of screen media (e.g., video, tablets) in early education are discussed. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Current Surgical Outcomes of Congenital Heart Surgery for Patients With Down Syndrome in Japan.

    PubMed

    Hoashi, Takaya; Hirahara, Norimichi; Murakami, Arata; Hirata, Yasutaka; Ichikawa, Hajime; Kobayashi, Junjiro; Takamoto, Shinichi

    2018-01-25

    Current surgical outcomes of congenital heart surgery for patients with Down syndrome are unclear.Methods and Results:Of 29,087 operations between 2008 and 2012 registered in the Japan Congenital Cardiovascular Surgery Database (JCCVSD), 2,651 were carried out for patients with Down syndrome (9%). Of those, 5 major biventricular repair procedures [ventricular septal defect repair (n=752), atrioventricular septal defect repair (n=452), patent ductus arteriosus closure (n=184), atrial septal defect repair (n=167), tetralogy of Fallot (TOF) repair (n=108)], as well as 2 major single ventricular palliations [bidirectional Glenn (n=21) and Fontan operation (n=25)] were selected and their outcomes were compared. The 90-day and in-hospital mortality rates for all 5 major biventricular repair procedures and bidirectional Glenn were similarly low in patients with Down syndrome compared with patients without Down syndrome. On the other hand, mortality after Fontan operation in patients with Down syndrome was significantly higher than in patients without Down syndrome (42/1,558=2.7% vs. 3/25=12.0%, P=0.005). Although intensive management of pulmonary hypertension is essential, analysis of the JCCVSD revealed favorable early prognostic outcomes after 5 major biventricular procedures and bidirectional Glenn in patients with Down syndrome. Indication of the Fontan operation for patients with Down syndrome should be carefully decided.

  7. Three-Dimensional Flow of Nanofluid Induced by an Exponentially Stretching Sheet: An Application to Solar Energy

    PubMed Central

    Khan, Junaid Ahmad; Mustafa, M.; Hayat, T.; Sheikholeslami, M.; Alsaedi, A.

    2015-01-01

    This work deals with the three-dimensional flow of nanofluid over a bi-directional exponentially stretching sheet. The effects of Brownian motion and thermophoretic diffusion of nanoparticles are considered in the mathematical model. The temperature and nanoparticle volume fraction at the sheet are also distributed exponentially. Local similarity solutions are obtained by an implicit finite difference scheme known as Keller-box method. The results are compared with the existing studies in some limiting cases and found in good agreement. The results reveal the existence of interesting Sparrow-Gregg-type hills for temperature distribution corresponding to some range of parametric values. PMID:25785857

  8. Stereoscopic particle image velocimetry investigations of the mixed convection exchange flow through a horizontal vent

    NASA Astrophysics Data System (ADS)

    Varrall, Kevin; Pretrel, Hugues; Vaux, Samuel; Vauquelin, Olivier

    2017-10-01

    The exchange flow through a horizontal vent linking two compartments (one above the other) is studied experimentally. This exchange is here governed by both the buoyant natural effect due to the temperature difference of the fluids in both compartments, and the effect of a (forced) mechanical ventilation applied in the lower compartment. Such a configuration leads to uni- or bi-directional flows through the vent. In the experiments, buoyancy is induced in the lower compartment thanks to an electrical resistor. The forced ventilation is applied in exhaust or supply modes and three different values of the vent area. To estimate both velocity fields and flow rates at the vent, measurements are realized at thermal steady state, flush the vent in the upper compartment using stereoscopic particle image velocimetry (SPIV), which is original for this kind of flow. The SPIV measurements allows the area occupied by both upward and downward flows to be determined.

  9. [Current approaches to evaluating the anatomic and functional status of the cornea].

    PubMed

    Avetisov, S E; Borodina, N V; Kobzova, M V; Musaeva, G M

    2010-01-01

    The review provides data on current methods for evaluating the anatomic and functional status of the cornea (light refraction, light transmission, and biomechanical properties, in particular). It analyzes the main advantages and disadvantages of basic (biomicroscopy, endothelial microscopy, ophthalmometry, topography, and pachymetry) and special (confocal microscopy, optical coherence tomography, ultrasound biomicroscopy, aberrometry, bidirectional corneal applanation, and keratoesthesiometry) studies.

  10. Axonal neurofilaments are nonessential elements of toxicant-induced reductions in fast axonal transport: video-enhanced differential interference microscopy in peripheral nervous system axons.

    PubMed

    Stone, J D; Peterson, A P; Eyer, J; Oblak, T G; Sickles, D W

    1999-11-15

    Neurofilament modification and accumulation, occurring in toxicant-induced neuropathies, has been proposed to compromise fast axonal transport and contribute to neurological symptoms or pathology. The current study compares the effects of the neurotoxicants acrylamide (ACR) and 2,5-hexanedione (2,5-HD) on the quantity of fast, bidirectional vesicular traffic within isolated mouse sciatic nerve axons from transgenic mice lacking axonal neurofilaments (Eyer and Peterson, Neuron 12, 1-20, 1994) and nontransgenic littermates possessing neurofilaments. Fast anterograde and retrograde membrane bound organelle (MBO) traffic was quantitated within axons, before and after toxicant exposure, using video-enhanced differential interference contrast (AVEC-DIC) microscopy. Addition of 0.7 mM ACR to the buffer bathing the nerve produced a time-dependent reduction in bidirectional transport with a similar time to onset and magnitude in both transgenic and nontransgenic mice. 2,5-HD (4 mM) exposure reduced bidirectional vesicle traffic by a similar amount in both transgenic and nontransgenic animals. The time to onset of the transport reduction was less and the magnitude of the reduction was greater with 2,5-HD compared to ACR. A single 10-min exposure to ACR or 2,5-HD produced a similar reduction in transport to that produced by prolonged (1 h) exposure. Nonneurotoxic propionamide or 3,4-hexanedione (3,4-HD) produced no changes in bidirectional transport in either transgenic or nontransgenic animals. We conclude that ACR or 2,5-HD produces a rapid, saturable, nonreversible, neurotoxicant-specific reduction in fast bidirectional transport within isolated peripheral nerve axons. These actions are mediated through direct modification of axonal component(s), which are independent of toxicant-induced modifications of, or accumulations of, neurofilaments. Copyright 1999 Academic Press.

  11. Bidirectional Reflectance of Flat, Optically Thick Particulate Layers: An Efficient Radiative Transfer Solution and Applications to Snow and Soil Surfaces

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Dlugach, Janna M.; Yanovitsku, Edgard G.; Zakharova, Nadia T.

    1999-01-01

    We describe a simple and highly efficient and accurate radiative transfer technique for computing bidirectional reflectance of a macroscopically flat scattering layer composed of nonabsorbing or weakly absorbing, arbitrarily shaped, randomly oriented and randomly distributed particles. The layer is assumed to be homogeneous and optically semi-infinite, and the bidirectional reflection function (BRF) is found by a simple iterative solution of the Ambartsumian's nonlinear integral equation. As an exact Solution of the radiative transfer equation, the reflection function thus obtained fully obeys the fundamental physical laws of energy conservation and reciprocity. Since this technique bypasses the computation of the internal radiation field, it is by far the fastest numerical approach available and can be used as an ideal input for Monte Carlo procedures calculating BRFs of scattering layers with macroscopically rough surfaces. Although the effects of packing density and coherent backscattering are currently neglected, they can also be incorporated. The FORTRAN implementation of the technique is available on the World Wide Web at http://ww,,v.giss.nasa.gov/-crmim/brf.html and can be applied to a wide range of remote sensing, engineering, and biophysical problems. We also examine the potential effect of ice crystal shape on the bidirectional reflectance of flat snow surfaces and the applicability of the Henyey-Greenstein phase function and the 6-Eddington approximation in calculations for soil surfaces.

  12. Single coil bistable, bidirectional micromechanical actuator

    DOEpatents

    Tabat, Ned; Guckel, Henry

    1998-09-15

    Micromechanical actuators capable of bidirectional and bistable operation can be formed on substrates using lithographic processing techniques. Bistable operation of the microactuator is obtained using a single coil and a magnetic core with a gap. A plunger having two magnetic heads is supported for back and forth linear movement with respect to the gap in the magnetic core, and is spring biased to a neutral position in which the two heads are on each side of the gap in the core. The single electrical coil is coupled to the core and is provided with electrical current to attract one of the heads toward the core by reluctance action to drive the plunger to a limit of travel in one direction. The current is then cut off and the plunger returns by spring action toward the gap, whereafter the current is reapplied to the coil to attract the other head of the plunger by reluctance action to drive the plunger to its other limit of travel. This process can be repeated at a time when switching of the actuator is required.

  13. Characterization and snubbing of a bidirectional MCT in a resonant ac link converter

    NASA Technical Reports Server (NTRS)

    Lee, Tony; Elbuluk, Malik E.; Zinger, Donald S.

    1993-01-01

    The MOS-Controlled Thyristor (MCT) is emerging as a powerful switch that combines the better characteristics of existing power devices. A study of switching stresses on an MCT switch under zero voltage resonant switching is presented. The MCT is used as a bidirectional switch in an ac/ac pulse density modulated inverter for induction motor drive. Current and voltage spikes are observed and analyzed with variations in the timing of the switching. Different snubber circuit configurations are under investigation to minimize the effect of these transients. The results will be extended to study and test the MCT switching in a medium power (5 hp) induction motor drive.

  14. Three-dimensional flow of Prandtl fluid with Cattaneo-Christov double diffusion

    NASA Astrophysics Data System (ADS)

    Hayat, Tasawar; Aziz, Arsalan; Muhammad, Taseer; Alsaedi, Ahmed

    2018-06-01

    This research paper intends to investigate the 3D flow of Prandtl liquid in the existence of improved heat conduction and mass diffusion models. Flow is created by considering linearly bidirectional stretchable sheet. Thermal and concentration diffusions are considered by employing Cattaneo-Christov double diffusion models. Boundary layer approach has been used to simplify the governing PDEs. Suitable nondimensional similarity variables correspond to strong nonlinear ODEs. Optimal homotopy analysis method (OHAM) is employed for solutions development. The role of various pertinent variables on temperature and concentration are analyzed through graphs. The physical quantities such as surface drag coefficients and heat and mass transfer rates at the wall are also plotted and discussed. Our results indicate that the temperature and concentration are decreasing functions of thermal and concentration relaxation parameters respectively.

  15. Experimental Acoustic Velocity Measurements in a Tidally Affected Stream

    USGS Publications Warehouse

    Storm, J.B.; ,

    2002-01-01

    The U.S. Geological Survey (USGS) constructed a continuous steamgaging station on the tidally affected Escatawpa River at Interstate 10 near Orange Grove, Mississippi, in August 2001. The gage collects water quantity parameters of stage and stream velocity, and water quality parameters of water temperature, specific conductance, and salinity. Data are transmitted to the local USGS office via the GOES satellite and are presented on a near real-time web page. Due to tidal effects, the stream has multiple flow regimes which include downstream, bi-directional, and reverse flows. Advances in acoustic technology have made it possible to gage streams of this nature where conventional methods have been unsuccessful. An experimental mount was designed in an attempt to recognize, describe, and quantify these flow regimes by using acoustic Doppler equipment.

  16. Effect of high altitude exposure on the hemodynamics of the bidirectional Glenn physiology: modeling incremented pulmonary vascular resistance and heart rate.

    PubMed

    Vallecilla, Carolina; Khiabani, Reza H; Sandoval, Néstor; Fogel, Mark; Briceño, Juan Carlos; Yoganathan, Ajit P

    2014-06-03

    The considerable blood mixing in the bidirectional Glenn (BDG) physiology further limits the capacity of the single working ventricle to pump enough oxygenated blood to the circulatory system. This condition is exacerbated under severe conditions such as physical activity or high altitude. In this study, the effect of high altitude exposure on hemodynamics and ventricular function of the BDG physiology is investigated. For this purpose, a mathematical approach based on a lumped parameter model was developed to model the BDG circulation. Catheterization data from 39 BDG patients at stabilized oxygen conditions was used to determine baseline flows and pressures for the model. The effect of high altitude exposure was modeled by increasing the pulmonary vascular resistance (PVR) and heart rate (HR) in increments up to 80% and 40%, respectively. The resulting differences in vascular flows, pressures and ventricular function parameters were analyzed. By simultaneously increasing PVR and HR, significant changes (p <0.05) were observed in cardiac index (11% increase at an 80% PVR and 40% HR increase) and pulmonary flow (26% decrease at an 80% PVR and 40% HR increase). Significant increase in mean systemic pressure (9%) was observed at 80% PVR (40% HR) increase. The results show that the poor ventricular function fails to overcome the increased preload and implied low oxygenation in BDG patients at higher altitudes, especially for those with high baseline PVRs. The presented mathematical model provides a framework to estimate the hemodynamic performance of BDG patients at different PVR increments. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Diagnostic blood-flow monitoring during therapeutic interventions using color Doppler optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Yazdanfar, Siavash; Kulkarni, Manish D.; Wong, Richard C. K.; Sivak, Michael J., Jr.; Willis, Joseph; Barton, Jennifer K.; Welch, Ashley J.; Izatt, Joseph A.

    1998-04-01

    A recently developed modality for blood flow measurement holds high promise in the management of bleeding ulcers. Color Doppler optical coherence tomography (CDOCT) uses low- coherence interferometry and digital signal processing to obtain precise localization of tissue microstructure simultaneous with bi-directional quantitation of blood flow. We discuss CDOCT as a diagnostic tool in the management of bleeding gastrointestinal lesions. Common treatments for bleeding ulcers include local injection of a vasoconstrictor, coagulation of blood via thermal contact or laser treatment, and necrosis of surrounding tissue with a sclerosant. We implemented these procedures in a rat dorsal skin flap model, and acquired CDOCT images before and after treatment. In these studies, CDOCT succeeded in identifying cessation of flow before it could be determined visually. Hence, we demonstrate the diagnostic capabilities of CDOCT in the regulation of bleeding in micron-scale vessels.

  18. Research on the business QoS and trustworthy and controllable strategies mechanism for energy internet

    NASA Astrophysics Data System (ADS)

    Zhang, Geng; Lu, Meiling; Zhang, Dahua; Zhou, Liang; Li, Likang

    2017-01-01

    Energy internet is a kind of power sharing network, which can realize the bidirectional flow of energy information on the basis of the existing power grid. It puts forward higher requirements for reliability and controllability of information communication, and all kinds of business QoS of the backbone network. So the research of business QoS and trustworthy and controllable strategies mechanism have an important significance for the development of energy internet. This paper mainly studies how to use the software defined network (SDN) to achieve business QoS, and provide QoS support for all kinds of business of the energy internet. Combined with the current development situation of the energy internet in our country, this paper researches the trustworthy and controllable strategies mechanism for energy internet, and proposes the transition scheme of the IPv6 credible network architecture based on SDN. This coordinates the contradiction between the growing demand for energy internet applications and the limitations of the energy internet technology itself.

  19. Organizational work-family resources as predictors of job performance and attitudes: the process of work-family conflict and enrichment.

    PubMed

    Odle-Dusseau, Heather N; Britt, Thomas W; Greene-Shortridge, Tiffany M

    2012-01-01

    The goal of the current study was to test a model where organizational resources (aimed at managing work and family responsibilities) predict job attitudes and supervisor ratings of performance through the mechanisms of work-family conflict and work-family enrichment. Employees (n = 174) at a large metropolitan hospital were surveyed at two time periods regarding perceptions of family supportive supervisor behaviors (FSSB), family supportive organizational perceptions (FSOP), bidirectional work-family conflict, bidirectional work-family enrichment, and job attitudes. Supervisors were also asked to provide performance ratings at Time 2. Results revealed FSSB at Time 1 predicted job satisfaction, organizational commitment and intention to leave, as well as supervisor ratings of performance, at Time 2. In addition, both work-family enrichment and family-work enrichment were found to mediate relationships between FSSB and various organizational outcomes, while work-family conflict was not a significant mediator. Results support further testing of supervisor behaviors specific to family support, as well models that include bidirectional work-family enrichment as the mechanism by which work-family resources predict employee and organizational outcomes.

  20. Bidirectional Associations Between Newlyweds' Marital Satisfaction and Marital Problems over Time.

    PubMed

    Lavner, Justin A; Karney, Benjamin R; Williamson, Hannah C; Bradbury, Thomas N

    2017-12-01

    Prevailing views of marital functioning generally adopt the view that marital problems predict decreases in marital satisfaction, but alternative theoretical perspectives raise the possibility that lowered satisfaction can also predict increases in problems. The current study sought to integrate and compare these perspectives by examining the bidirectional cross-lagged associations between newlyweds' reports of their marital satisfaction and marital problems over the first 4 years of marriage. Using annual assessments from 483 heterosexual newlywed couples, we find evidence for problem-to-satisfaction linkages as well as satisfaction-to-problem linkages. Satisfaction was a stronger predictor of marital problems early in marriage but not as time passed; by Year 4 only problem-to-satisfaction linkages remained significant. These findings are consistent with the idea that couples with more problems go on to report lower levels of satisfaction and couples with lower levels of satisfaction go on to report more marital problems. This dynamic interplay between global judgments about relationship satisfaction and ongoing specific relationship difficulties highlights the value of examining bidirectional effects to better understand marital functioning over time. © 2016 Family Process Institute.

  1. Laser pulse bidirectional reflectance from CALIPSO mission

    NASA Astrophysics Data System (ADS)

    Lu, Xiaomei; Hu, Yongxiang; Yang, Yuekui; Vaughan, Mark; Liu, Zhaoyan; Rodier, Sharon; Hunt, William; Powell, Kathy; Lucker, Patricia; Trepte, Charles

    2018-06-01

    This paper presents an innovative retrieval method that translates the CALIOP land surface laser pulse returns into the surface bidirectional reflectance. To better analyze the surface returns, the CALIOP receiver impulse response and the downlinked samples' distribution at 30 m vertical resolution are discussed. The saturated laser pulse magnitudes from snow and ice surfaces are recovered based on information extracted from the tail end of the surface signal. The retrieved snow surface bidirectional reflectance is compared with reflectance from both CALIOP cloud-covered regions and MODIS BRDF-albedo model parameters. In addition to the surface bidirectional reflectance, the column top-of-atmosphere bidirectional reflectances are calculated from the CALIOP lidar background data and compared with the bidirectional reflectances derived from WFC radiance measurements. The retrieved CALIOP surface bidirectional reflectance and column top-of-atmosphere bidirectional reflectance results provide unique information to complement existing MODIS standard data products and are expected to have valuable applications for modelers.

  2. GluN2B-containing NMDA receptors blockade rescues bidirectional synaptic plasticity in the bed nucleus of the stria terminalis of cocaine self-administering rats.

    PubMed

    deBacker, Julian; Hawken, Emily R; Normandeau, Catherine P; Jones, Andrea A; Di Prospero, Cynthia; Mechefske, Elysia; Gardner Gregory, James; Hayton, Scott J; Dumont, Éric C

    2015-01-01

    Drugs of abuse have detrimental effects on homeostatic synaptic plasticity in the motivational brain network. Bidirectional plasticity at excitatory synapses helps keep neural circuits within a functional range to allow for behavioral flexibility. Therefore, impaired bidirectional plasticity of excitatory synapses may contribute to the behavioral hallmarks of addiction, yet this relationship remains unclear. Here we tracked excitatory synaptic strength in the oval bed nucleus of the stria terminalis (ovBNST) using whole-cell voltage-clamp recordings in brain slices from rats self-administering sucrose or cocaine. In the cocaine group, we measured both a persistent increase in AMPA to NMDA ratio (A:N) and slow decay time of NMDA currents throughout the self-administration period and after withdrawal from cocaine. In contrast, the sucrose group exhibited an early increase in A:N ratios (acquisition) that returned toward baseline values with continued self-administration (maintenance) and after withdrawal. The sucrose rats also displayed a decrease in NMDA current decay time with continued self-administration (maintenance), which normalized after withdrawal. Cocaine self-administering rats exhibited impairment in NMDA-dependent long-term depression (LTD) that could be rescued by GluN2B-containing NMDA receptor blockade. Sucrose self-administering rats demonstrated no impairment in NMDA-dependent LTD. During the maintenance period of self-administration, in vivo (daily intraperitoneally for 5 days) pharmacologic blockade of GluN2B-containing NMDA receptors did not reduce lever pressing for cocaine. However, in vivo GluN2B blockade did normalize A:N ratios in cocaine self-administrating rats, and dissociated the magnitude of ovBNST A:N ratios from drug-seeking behavior after protracted withdrawal. Altogether, our data demonstrate when and how bidirectional plasticity at ovBNST excitatory synapses becomes dysfunctional with cocaine self-administration and that NMDA-mediated potentiation of AMPA receptors in this region may be part of the neural circuits of drug relapse.

  3. On the formalization of multi-scale and multi-science processes for integrative biology

    PubMed Central

    Díaz-Zuccarini, Vanessa; Pichardo-Almarza, César

    2011-01-01

    The aim of this work is to introduce the general concept of ‘Bond Graph’ (BG) techniques applied in the context of multi-physics and multi-scale processes. BG modelling has a natural place in these developments. BGs are inherently coherent as the relationships defined between the ‘elements’ of the graph are strictly defined by causality rules and power (energy) conservation. BGs clearly show how power flows between components of the systems they represent. The ‘effort’ and ‘flow’ variables enable bidirectional information flow in the BG model. When the power level of a system is low, BGs degenerate into signal flow graphs in which information is mainly one-dimensional and power is minimal, i.e. they find a natural limitation when dealing with populations of individuals or purely kinetic models, as the concept of energy conservation in these systems is no longer relevant. The aim of this work is twofold: on the one hand, we will introduce the general concept of BG techniques applied in the context of multi-science and multi-scale models and, on the other hand, we will highlight some of the most promising features in the BG methodology by comparing with examples developed using well-established modelling techniques/software that could suggest developments or refinements to the current state-of-the-art tools, by providing a consistent framework from a structural and energetic point of view. PMID:22670211

  4. What goes up might come down: Backflow in the conduits of persistently degassing volcanoes and ramifications for melt-inclusion analysis

    NASA Astrophysics Data System (ADS)

    Suckale, J.; Qin, Z.; Picchi, D.; Keller, T.

    2017-12-01

    Many active volcanoes erupt significantly less magma than they degas, implying that large quantities of magma must descend back into the plumbing system after degassing. The resulting bidirectional flow field in the volcanic conduit is fundamentally unstable. These instabilities are important to understand, because they likely control the episodicity of eruptive behavior observed at persistently degassing volcanoes. Laboratory experiments have provided invaluable insights into the flow regimes that may arise in volcanic conduits, but are not straightforward to scale up to volcanic systems. The goal of this study is to use direct numerical simulations to virtually reproduce the analogue experiments by Stevenson and Blake, 1998, compare them to simple analytical models and gain insights into the different flow regimes and interface instabilities observed in actual volcanic conduits. Direct numerical simulations provide a compelling complement to analogue experiments, because they are not constrained by the scales or flow properties achievable in a laboratory setting. By linking virtual and analogue experiments, we show that the interface between ascending and descending fluid is not usually stationary in volcanic conduits (see fig). The intuition that buoyant, volatile-rich magma moves up while heavy, degassed magma moves down is hence not generally true in bidirectional conduit flow. Instead, our results show that a potentially significant portion of the volatile-rich magma flows downwards despite its positive buoyancy - a process commonly referred to as backflow. The existence of backflow in volcanic conduits has potentially important ramifications for understanding melt-inclusion trends, because it affects exsolved and dissolved volatile components differently. Our preliminary results suggest that carbon dioxide bubbles exsolved at depth tend to decouple from the backflow and escape into the upward moving portion of the fluid, while dissolved water is recycled back to depth. The ascending magma, which is likely sampled by eruptive products, is hence enriched in carbon dioxide but deprived of water, which could be reflected in the common observation that melt inclusions from persistently degassing volcanic systems appear to be shifted to higher carbon dioxide contents for a given amount of water.

  5. Tail dependence and information flow: Evidence from international equity markets

    NASA Astrophysics Data System (ADS)

    Al Rahahleh, Naseem; Bhatti, M. Ishaq; Adeinat, Iman

    2017-05-01

    Bhatti and Nguyen (2012) used the copula approach to measure the tail dependence between a number of international markets. They observed that some country pairs exhibit only left-tail dependence whereas others show only right-tail. However, the flow of information from uni-dimensional (one-tail) to bi-dimensional (two-tails) between various markets was not accounted for. In this study, we address the flow of information of this nature by using the dynamic conditional correlation (DCC-GARCH) model. More specifically, we use various versions of the DCC models to explain the nexus between the information flow of international equity and to explain the stochastic forward vs. backward dynamics of financial markets based on data for a 15-year period comprising 3,782 observations. We observed that the information flow between the US and Hong Kong markets and between the US and Australian markets are bi-directional. We also observed that the DCC model captures a wider co-movement structure and inter-connectedness compared to the symmetric Joe-Clayton copula.

  6. Congestion and communication in confined ant traffic

    NASA Astrophysics Data System (ADS)

    Gravish, Nick; Gold, Gregory; Zangwill, Andrew; Goodisman, Michael A. D.; Goldman, Daniel I.

    2014-03-01

    Many social animals move and communicate within confined spaces. In subterranean fire ants Solenopsis invicta, mobility within crowded nest tunnels is important for resource and information transport. Within confined tunnels, communication and traffic flow are at odds: trafficking ants communicate through tactile interactions while stopped, yet ants that stop to communicate impose physical obstacles on the traffic. We monitor the bi-directional flow of fire ant workers in laboratory tunnels of varied diameter D. The persistence time of communicating ant aggregations, τ, increases approximately linearly with the number of participating ants, n. The sensitivity of traffic flow increases as D decreases and diverges at a minimum diameter, Dc. A cellular automata model incorporating minimal traffic features--excluded volume and communication duration--reproduces features of the experiment. From the model we identify a competition between information transfer and the need to maintain jam-free traffic flow. We show that by balancing information transfer and traffic flow demands, an optimum group strategy exists which maximizes information throughput. We acknowledge funding from NSF PoLS #0957659 and #PHY-1205878.

  7. Lamination cooling system

    DOEpatents

    Rippel, Wally E.; Kobayashi, Daryl M.

    2005-10-11

    An electric motor, transformer or inductor having a lamination cooling system including a stack of laminations, each defining a plurality of apertures at least partially coincident with apertures of adjacent laminations. The apertures define a plurality of cooling-fluid passageways through the lamination stack, and gaps between the adjacent laminations are sealed to prevent a liquid cooling fluid in the passageways from escaping between the laminations. The gaps are sealed by injecting a heat-cured sealant into the passageways, expelling excess sealant, and heat-curing the lamination stack. The apertures of each lamination can be coincident with the same-sized apertures of adjacent laminations to form straight passageways, or they can vary in size, shape and/or position to form non-axial passageways, angled passageways, bidirectional passageways, and manifold sections of passageways that connect a plurality of different passageway sections. Manifold members adjoin opposite ends of the lamination stack, and each is configured with one or more cavities to act as a manifold to adjacent passageway ends. Complex manifold arrangements can create bidirectional flow in a variety of patterns.

  8. Two new families of high-gain dc-dc power electronic converters for dc-microgrids

    NASA Astrophysics Data System (ADS)

    Prabhala, Venkata Anand Kishore

    Distributing the electric power in dc form is an appealing solution in many applications such as telecommunications, data centers, commercial buildings, and microgrids. A high gain dc-dc power electronic converter can be used to individually link low-voltage elements such as solar panels, fuel cells, and batteries to the dc voltage bus which is usually 400 volts. This way, it is not required to put such elements in a series string to build up their voltages. Consequently, each element can function at it optimal operating point regardless of the other elements in the system. In this dissertation, first a comparative study of dc microgrid architectures and their advantages over their ac counterparts is presented. Voltage level selection of dc distribution systems is discussed from the cost, reliability, efficiency, and safety standpoints. Next, a new family of non-isolated high-voltage-gain dc-dc power electronic converters with unidirectional power flow is introduced. This family of converters benefits from a low voltage stress across its switches. The proposed topologies are versatile as they can be utilized as single-input or double-input power converters. In either case, they draw continuous currents from their sources. Lastly, a bidirectional high-voltage-gain dc-dc power electronic converter is proposed. This converter is comprised of a bidirectional boost converter which feeds a switched-capacitor architecture. The switched-capacitor stage suggested here has several advantages over the existing approaches. For example, it benefits from a higher voltage gain while it uses less number of capacitors. The proposed converters are highly efficient and modular. The operating modes, dc voltage gain, and design procedure for each converter are discussed in details. Hardware prototypes have been developed in the lab. The results obtained from the hardware agree with those of the simulation models.

  9. Enhancing Bidirectional Electron Transfer of Shewanella oneidensis by a Synthetic Flavin Pathway.

    PubMed

    Yang, Yun; Ding, Yuanzhao; Hu, Yidan; Cao, Bin; Rice, Scott A; Kjelleberg, Staffan; Song, Hao

    2015-07-17

    Flavins regulate the rate and direction of extracellular electron transfer (EET) in Shewanella oneidensis. However, low concentration of endogenously secreted flavins by the wild-type S. oneidensis MR-1 limits its EET efficiency in bioelectrochemical systems (BES). Herein, a synthetic flavin biosynthesis pathway from Bacillus subtilis was heterologously expressed in S. oneidensis MR-1, resulting in ∼25.7 times' increase in secreted flavin concentration. This synthetic flavin module enabled enhanced bidirectional EET rate of MR-1, in which its maximum power output in microbial fuel cells increased ∼13.2 times (from 16.4 to 233.0 mW/m(2)), and the inward current increased ∼15.5 times (from 15.5 to 255.3 μA/cm(2)).

  10. An iterative bidirectional heuristic placement algorithm for solving the two-dimensional knapsack packing problem

    NASA Astrophysics Data System (ADS)

    Shiangjen, Kanokwatt; Chaijaruwanich, Jeerayut; Srisujjalertwaja, Wijak; Unachak, Prakarn; Somhom, Samerkae

    2018-02-01

    This article presents an efficient heuristic placement algorithm, namely, a bidirectional heuristic placement, for solving the two-dimensional rectangular knapsack packing problem. The heuristic demonstrates ways to maximize space utilization by fitting the appropriate rectangle from both sides of the wall of the current residual space layer by layer. The iterative local search along with a shift strategy is developed and applied to the heuristic to balance the exploitation and exploration tasks in the solution space without the tuning of any parameters. The experimental results on many scales of packing problems show that this approach can produce high-quality solutions for most of the benchmark datasets, especially for large-scale problems, within a reasonable duration of computational time.

  11. Development of a bidirectional ring thermal actuator

    NASA Astrophysics Data System (ADS)

    Stevenson, Mathew; Yang, Peng; Lai, Yongjun; Mechefske, Chris

    2007-10-01

    A new planar micro electrothermal actuator capable of bidirectional rotation is presented. The ring thermal actuator has a wheel-like geometry with eight arms connecting an outer ring to a central hub. Thermal expansion of the arms results in a rotation of the outer ring about its center. An analytical model is developed for the electrothermal and thermal-mechanical aspects of the actuator's operation. Finite element analysis is used to validate the analytic study. The actuator has been fabricated using the multi-user MEMS process and experimental displacement results are compared with model predictions. Experiments show a possible displacement of 7.4 µm in each direction. Also, by switching the current between the arms it is possible to achieve an oscillating motion.

  12. Balancing the Power-to-Load Ratio for a Novel Variable Geometry Wave Energy Converter with Nonideal Power Take-Off in Regular Waves: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tom, Nathan M; Yu, Yi-Hsiang; Wright, Alan D

    This work attempts to balance power absorption against structural loading for a novel variable geometry wave energy converter. The variable geometry consists of four identical flaps that will be opened in ascending order starting with the flap closest to the seafloor and moving to the free surface. The influence of a pitch motion constraint on power absorption when utilizing a nonideal power take-off (PTO) is examined and found to reduce the losses associated with bidirectional energy flow. The power-to-load ratio is evaluated using pseudo-spectral control to determine the optimum PTO torque based on a multiterm objective function. The pseudo-spectral optimalmore » control problem is extended to include load metrics in the objective function, which may now consist of competing terms. Separate penalty weights are attached to the surge-foundation force and PTO control torque to tune the optimizer performance to emphasize either power absorption or load shedding. PTO efficiency is not included in the objective function, but the penalty weights are utilized to limit the force and torque amplitudes, thereby reducing losses associated with bidirectional energy flow. Results from pseudo-spectral control demonstrate that shedding a portion of the available wave energy can provide greater reductions in structural loads and reactive power.« less

  13. Different Forms of Spirituality and Heavy Episodic Drinking among College Students

    ERIC Educational Resources Information Center

    Klassen, Brian J.; Grekin, Emily R.

    2017-01-01

    Objective: The current study examined prospective, bidirectional relationships between 3 measures of spirituality (Daily Spiritual Experiences, Positive Religious Coping, and Negative Religious Coping) and frequency of heavy episodic drinking. Participants: Three hundred ninety-one students attending a large, public university in the Midwest.…

  14. High efficiency H6 single-phase transformerless grid-tied PV inverter with proposed modulation for reactive power generation

    NASA Astrophysics Data System (ADS)

    Almasoudi, Fahad M.; Alatawi, Khaled S.; Matin, Mohammad

    2017-08-01

    Implementation of transformerless inverters in PV grid-tied system offer great benefits such as high efficiency, light weight, low cost, etc. Most of the proposed transformerless inverters in literature are verified for only real power application. Currently, international standards such as VDE-AR-N 4105 has demanded that PV grid-tied inverters should have the ability of controlling a specific amount of reactive power. Generation of reactive power cannot be accomplished in single phase transformerless inverter topologies because the existing modulation techniques are not adopted for a freewheeling path in the negative power region. This paper enhances a previous high efficiency proposed H6 trnasformerless inverter with SiC MOSFETs and demonstrates new operating modes for the generation of reactive power. A proposed pulse width modulation (PWM) technique is applied to achieve bidirectional current flow through freewheeling state. A comparison of the proposed H6 transformerless inverter using SiC MOSFETs and Si MOSFTEs is presented in terms of power losses and efficiency. The results show that reactive power control is attained without adding any additional active devices or modification to the inverter structure. Also, the proposed modulation maintains a constant common mode voltage (CM) during every operating mode and has low leakage current. The performance of the proposed system verifies its effectiveness in the next generation PV system.

  15. The Consequences of Insufficient Sleep for Adolescents: Links Between Sleep and Emotional Regulation.

    ERIC Educational Resources Information Center

    Dahl, Ronald E.

    1999-01-01

    Reviews current scientific and clinical information regarding consequences of insufficient sleep in adolescents, including sleepiness; tiredness; changes in mood, attention, and behavior; emotional and behavior problems' effects on sleep patterns; and bidirectional effects. Lifestyle forces are pushing teens' sleep/arousal balance in the wrong…

  16. Modelling the Air–Surface Exchange of Ammonia from the Field to Global Scale

    EPA Science Inventory

    The Working Group addressed the current understanding and uncertainties in the processes controlling ammonia (NH3) bi-directional exchange, and in the application of numerical models to describe these processes. As a starting point for the discussion, the Working Group drew on th...

  17. Considerations on the relationship between white and red centerline runway lights and RVR (Runway Visual Range).

    DOT National Transportation Integrated Search

    1972-01-01

    The runway visual range (RVR) for a Type L-850 bidirectional centerline runway light has been calculated for the red and white output ports at three different current settings for both day and night illuminance thresholds. The calculations are based ...

  18. Nonlinear mechanisms of two-dimensional wave-wave transformations in the initially coupled acoustic structure

    NASA Astrophysics Data System (ADS)

    Vorotnikov, K.; Starosvetsky, Y.

    2018-01-01

    The present study concerns two-dimensional nonlinear mechanisms of bidirectional and unidirectional channeling of longitudinal and shear waves emerging in the locally resonant acoustic structure. The system under consideration comprises an oscillatory chain of the axially coupled masses. Each mass of the chain is subject to the local linear potential along the lateral direction and incorporates the lightweight internal rotator. In the present work, we demonstrate the emergence of special resonant regimes of complete bi- and unidirectional transitions between the longitudinal and the shear waves of the locally resonant chain. These regimes are manifested by the two-dimensional energy channeling between the longitudinal and the shear traveling waves in the recurrent as well as the irreversible fashion. We show that the spatial control of the two dimensional energy flow between the longitudinal and the shear waves is solely governed by the motion of the internal rotators. Nonlinear analysis of the regimes of a bidirectional wave channeling unveils their global bifurcation structure and predicts the zones of their spontaneous transitions from a complete bi-directional wave channeling to the one-directional entrapment. An additional regime of a complete irreversible resonant transformation of the longitudinal wave into a shear wave is analyzed in the study. The intrinsic mechanism governing the unidirectional wave reorientation is described analytically. The results of the analysis of both mechanisms are substantiated by the numerical simulations of the full model and are found to be in a good agreement.

  19. Bidirectional Transfer between Metaphorical Related Domains in Implicit Learning of Form-Meaning Connections

    PubMed Central

    Yang, Zhiliang; Dienes, Zoltan

    2013-01-01

    People can implicitly learn a connection between linguistic forms and meanings, for example between specific determiners (e.g. this, that…) and the type of nouns to which they apply. Li et al (2013) recently found that transfer of form-meaning connections from a concrete domain (height) to an abstract domain (power) was achieved in a metaphor-consistent way without awareness, showing that unconscious knowledge can be abstract and flexibly deployed. The current study aims to determine whether people transfer knowledge of form-meaning connections not only from a concrete domain to an abstract one, but also vice versa, consistent with metaphor representation being bi-directional. With a similar paradigm as used by Li et al, participants learnt form- meaning connections of different domains (concrete vs. abstract) and then were tested on two kinds of generalizations (same and different domain generalization). As predicted, transfer of form-meaning connections occurred bidirectionally when structural knowledge was unconscious. Moreover, the present study also revealed that more transfer occurred between metaphorically related domains when judgment knowledge was conscious (intuition) rather than unconscious (guess). Conscious and unconscious judgment knowledge may have different functional properties. PMID:23844159

  20. Socio-Hydrology: Conceptual and Methodological Challenges in the Bidirectional Coupling of Human and Water Systems

    NASA Astrophysics Data System (ADS)

    Scott, C. A.

    2014-12-01

    This presentation reviews conceptual advances in the emerging field of socio-hydrology that focuses on coupled human and water systems. An important current challenge is how to better couple the bidirectional influences between human and water systems, which lead to emergent dynamics. The interactions among (1) the structure and dynamics of systems with (2) human values and norms lead to (3) outcomes, which in turn influence subsequent interactions. Human influences on hydrological systems are relatively well understood, chiefly resulting from developments in the field of water resources. The ecosystem-service concept of cultural value has expanded understanding of decision-making beyond economic rationality criteria. Hydrological impacts on social processes are less well developed conceptually, but this is changing with growing attention to vulnerability, adaptation, and resilience, particularly in the face of climate change. Methodological limitations, especially in characterizing the range of human responses to hydrological events and drivers, still pose challenges to modeling bidirectional human-water influences. Evidence from multiple case studies, synthesized in more broadly generic syndromes, helps surmount these methodological limitations and offers the potential to improve characterization and quantification of socio-hydrological systems.

  1. Bidirectional Coupling between Astrocytes and Neurons Mediates Learning and Dynamic Coordination in the Brain: A Multiple Modeling Approach

    PubMed Central

    Wade, John J.; McDaid, Liam J.; Harkin, Jim; Crunelli, Vincenzo; Kelso, J. A. Scott

    2011-01-01

    In recent years research suggests that astrocyte networks, in addition to nutrient and waste processing functions, regulate both structural and synaptic plasticity. To understand the biological mechanisms that underpin such plasticity requires the development of cell level models that capture the mutual interaction between astrocytes and neurons. This paper presents a detailed model of bidirectional signaling between astrocytes and neurons (the astrocyte-neuron model or AN model) which yields new insights into the computational role of astrocyte-neuronal coupling. From a set of modeling studies we demonstrate two significant findings. Firstly, that spatial signaling via astrocytes can relay a “learning signal” to remote synaptic sites. Results show that slow inward currents cause synchronized postsynaptic activity in remote neurons and subsequently allow Spike-Timing-Dependent Plasticity based learning to occur at the associated synapses. Secondly, that bidirectional communication between neurons and astrocytes underpins dynamic coordination between neuron clusters. Although our composite AN model is presently applied to simplified neural structures and limited to coordination between localized neurons, the principle (which embodies structural, functional and dynamic complexity), and the modeling strategy may be extended to coordination among remote neuron clusters. PMID:22242121

  2. Cavitation Characteristics of a NACA 63-424 Hydrofoil and Performance Comparison with a Bidirectional Version of the Foil

    NASA Astrophysics Data System (ADS)

    Nedyalkov, Ivaylo; Wosnik, Martin

    2012-11-01

    A NACA 63-424 hydrofoil with a 75 mm chord and a 152 mm span was tested in the recently renovated 6-inch high-speed water tunnel at the University of New Hampshire. The NACA 63-424 foil is being considered for use on rotors of marine hydrokinetic turbines, including the US Department of Energy Reference Horizontal Axis Turbine (RHAT) for tidal and ocean current applications. For various angles of attack, the foil was tested at speeds ranging from 2 m/s to 12 m/s. Pressure in the test section was varied independently. For each angle, speed and pressure setting, high speed videos were recorded (at 3600 frames per second and above). Cavitation inception and desinance were obtained. Lift and drag were measured using a new 2-component force balance. In tidal turbines applications, bidirectional foils do not require pitch control, hence the experiments were repeated for a bidirectional version of the NACA 63-424 foil and the characteristics of the two foils were compared. The results can be used to predict cavitation inception and performance of marine hydrokinetic turbines, for a given site, deployment depth and and tip speed ratio.

  3. Circulation of fluids in the gastrovascular system of a stoloniferan octocoral.

    PubMed

    Parrin, Austin P; Netherton, Sarah E; Bross, Lori S; McFadden, Catherine S; Blackstone, Neil W

    2010-10-01

    Cilia-based transport systems characterize sponges and placozoans. Cilia are employed in cnidarian gastrovascular systems as well, but typically function in concert with muscular contractions. Previous reports suggest that anthozoans may be an exception to this pattern, utilizing only cilia in their gastrovascular systems. With an inverted microscope and digital image analysis, we used stoloniferan octocoral colonies growing on microscope cover glass to quantitatively describe the movement of fluids in this system for the first time. Flow in stolons (diameter ≈300 μm) is simultaneously bidirectional, with average velocities of 100-200 μm/s in each direction. Velocities are maximal immediately adjacent to the stolon wall and decrease to a minimum in the center of the stolon. Flow velocity is unaffected by stolonal contractions, suggesting that muscular peristalsis is not a factor in propelling the flow. Stolon intersections (diameter ≈500 μm) occur below polyps and serve as traffic roundabouts with unidirectional, circular flow. Such cilia-driven transport may be the plesiomorphic state for the gastrovascular system of cnidarians.

  4. Microprobes For Blood Flow Measurements In Tissue And Small Vessels

    NASA Astrophysics Data System (ADS)

    Oberg, P. A.; Salerud, E. G.

    1988-04-01

    Laser Doppler flowmetry is a method for the continuous and non-invasive recording of tissue blood flow. The method has already proved to be advantageous in a number of clinical as well as theoretical medical disciplines. In dermatology, plastic- and gastrointestinal surgery laser Doppler measurements have substantially contributed to increase knowledge of microvascular perfusion. In experimental medicine, the method has been used in the study of a great variety of microvascular problems. Spontaneous rhythmical variations, spatial and temporal fluctuations in human skin blood flow are mentioned as examples of problem areas in which new knowledge has been generated. The method has facilitated further investigations of the nature of spongeous bone blood flow, testis and kidney cortex blood flow. Recently we have showed that a variant of the laser Doppler method principle, using a single optical fiber, can be advantageous in deep tissue measurements. With this method laser light is transmitted bidirectionally in a single fiber. The tissue trauma which affects blood flow can be minimized by introducing small diameter fibers (0.1-0.5 mm). A special set-up utilizing the same basic principle has been used for the recording of blood flow in small vessels.

  5. Foreign investment in Asia in the 1990s: trends, problems and implications for manpower movements.

    PubMed

    Sekiguchi, S

    1992-01-01

    Direct foreign investment (DFI) is described as an international reallocation of managerial resources through which manpower moves across borders bidirectionally. This paper describes the diversity and rapidity of change in DFI for flows among North America, western Europe, Japan, ASEAN, Taiwan, China, Hong Kong, Korea, and Russia, and the implications for manpower movements. The US share of DFI in the Pacific Rim has declined while that of Japan and Western Europe has increased with the newly industrialized economies emerging regionally as net capital exporters. US and western European DFI will increasingly turn toward the Americas and Europe. Diminished US DFI will likely be compensated by Asian intraregional flows led by Japan, South Korea, Singapore, and Hong Kong. As for migration trends, bidirectinal flows of unskilled and professional labor may be stimulated by DFI, but only limited direct effects upon manpower movements should be expected.

  6. Cattaneo-Christov Heat Flux Model for MHD Three-Dimensional Flow of Maxwell Fluid over a Stretching Sheet.

    PubMed

    Rubab, Khansa; Mustafa, M

    2016-01-01

    This letter investigates the MHD three-dimensional flow of upper-convected Maxwell (UCM) fluid over a bi-directional stretching surface by considering the Cattaneo-Christov heat flux model. This model has tendency to capture the characteristics of thermal relaxation time. The governing partial differential equations even after employing the boundary layer approximations are non linear. Accurate analytic solutions for velocity and temperature distributions are computed through well-known homotopy analysis method (HAM). It is noticed that velocity decreases and temperature rises when stronger magnetic field strength is accounted. Penetration depth of temperature is a decreasing function of thermal relaxation time. The analysis for classical Fourier heat conduction law can be obtained as a special case of the present work. To our knowledge, the Cattaneo-Christov heat flux model law for three-dimensional viscoelastic flow problem is just introduced here.

  7. Bidirectional Teleportation Protocol in Quantum Wireless Multi-hop Network

    NASA Astrophysics Data System (ADS)

    Cai, Rui; Yu, Xu-Tao; Zhang, Zai-Chen

    2018-06-01

    We propose a bidirectional quantum teleportation protocol based on a composite GHZ-Bell state. In this protocol, the composite GHZ-Bell state channel is transformed into two-Bell state channel through gate operations and single qubit measurements. The channel transformation will lead to different kinds of quantum channel states, so a method is proposed to help determine the unitary matrices effectively under different quantum channels. Furthermore, we discuss the bidirectional teleportation protocol in the quantum wireless multi-hop network. This paper is aimed to provide a bidirectional teleportation protocol and study the bidirectional multi-hop teleportation in the quantum wireless communication network.

  8. Bidirectional Teleportation Protocol in Quantum Wireless Multi-hop Network

    NASA Astrophysics Data System (ADS)

    Cai, Rui; Yu, Xu-Tao; Zhang, Zai-Chen

    2018-02-01

    We propose a bidirectional quantum teleportation protocol based on a composite GHZ-Bell state. In this protocol, the composite GHZ-Bell state channel is transformed into two-Bell state channel through gate operations and single qubit measurements. The channel transformation will lead to different kinds of quantum channel states, so a method is proposed to help determine the unitary matrices effectively under different quantum channels. Furthermore, we discuss the bidirectional teleportation protocol in the quantum wireless multi-hop network. This paper is aimed to provide a bidirectional teleportation protocol and study the bidirectional multi-hop teleportation in the quantum wireless communication network.

  9. Physical Monitoring of Flow Into and Within Great Salt Lake, Utah

    NASA Astrophysics Data System (ADS)

    Kenney, T. A.; Naftz, D. L.; Perschon, W. C.

    2006-12-01

    Great Salt Lake (GSL) is the hydrologic terminus for the eastern part of the Great Basin. As the largest inland waterbody in the Western United States, GSL plays a critical ecologic role for many migratory bird species. In terms of harvest quantity and quality, the brine shrimp (Artemia) fishery of GSL is among the strongest in the world. The characteristic of GSL as a hydrologic sink amplifies anthropogenic activities throughout the basin, most specifically activities that occur along its eastern and southern shores, the urban corridor of the Wasatch Front. In 1959 GSL was divided into north and south parts by a rock-fill railroad causeway. Since then, an extreme density gradient between the north and south part exists as a result of limited conveyance of water from the south part where more than 95 percent of the total freshwater input occurs (Loving, and others, 2000). To date, little is known about the loading and cycling of various chemical constituents associated with human activities including nutrients, selenium, and mercury. Hydroacoustic technology, specifically acoustic Doppler technology, is currently being used to obtain a better physical understanding of GSL. Since 1999, stratified bi-directional discharge has been measured at the causeway breach with an acoustic Doppler current profiler. From these measurements, net flow components to the north and south have been used to assess the movement of water and salt through the causeway. Low hydraulic gradients and variable backwater conditions at the two largest inflows to GSL required the deployment of in-situ acoustic Doppler velocity meters to accurately compute continuous discharge, critical for constituent loading analyses. These discharge records, computed using the index velocity method, show sensitivity to large wind events that can lead to a complete reversal of flow. Velocity profiles acquired during two multi-day water-quality synoptic sampling runs with acoustic Doppler current profilers have identified surface currents related to both freshwater inflow and wind throughout main body GSL. Velocity profiles have also determined the flow direction and magnitude of a persistent anoxic layer at depth in the south part of GSL. Movement of this layer between the two main basins of the south along a topographically high divide has also been documented (5 to 31 centimeters per second). References Cited Loving, B.L., Waddell, K.M., and Miller, C.W., 2000, Water and salt balance of Great Salt Lake, Utah, and simulation of water and salt movement through the causeway, 1987-98, U.S. Geological Survey Water-Resources Investigations Report 00-4221, 31 p.

  10. A Sequential Analysis of Parent-Child Interactions in Anxious and Nonanxious Families

    ERIC Educational Resources Information Center

    Williams, Sarah R.; Kertz, Sarah J.; Schrock, Matthew D.; Woodruff-Borden, Janet

    2012-01-01

    Although theoretical work has suggested that reciprocal behavior patterns between parent and child may be important in the development of childhood anxiety, most empirical work has failed to consider the bidirectional nature of interactions. The current study sought to address this limitation by utilizing a sequential approach to exploring…

  11. Tact Training versus Bidirectional Intraverbal Training in Teaching a Foreign Language

    ERIC Educational Resources Information Center

    Dounavi, Katerina

    2014-01-01

    The current study involved an evaluation of the emergence of untrained verbal relations as a function of 3 different foreign-language teaching strategies. Two Spanish-speaking adults received foreign-language (English) tact training and native-to-foreign and foreign-to-native intraverbal training. Tact training and native-to-foreign intraverbal…

  12. Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States

    USDA-ARS?s Scientific Manuscript database

    Several lineages of influenza A viruses (IAV) currently circulate in North American pigs. Genetic diversity is further increased by the bidirectional transmission of IAV between swine and humans and the subsequent processes of antigenic shift and drift. Such evolution can be the basis for changes in...

  13. Generalized model of a bidirectional DC-DC converter

    NASA Astrophysics Data System (ADS)

    Hinov, Nikolay; Arnaudov, Dimitar; Penev, Dimitar

    2017-12-01

    The following paperwork presents models of bidirectional converters. A classic bidirectional converter and a new bidirectional circuit based on a ZCS resonant converter are investigated and compared. The developed models of these converters allow comparison between their characteristics showing their advantages and disadvantages. The models allow precise models of energy storage elements to be implemented as well, which is useful for examination of energy storage systems.

  14. Influence of exercise induced hyperlactatemia on retinal blood flow during normo- and hyperglycemia.

    PubMed

    Garhöfer, Gerhard; Kopf, Andreas; Polska, Elzbieta; Malec, Magdalena; Dorner, Guido T; Wolzt, Michael; Schmetterer, Leopold

    2004-05-01

    Short term hyperglycemia has previously been shown to induce a blood flow increase in the retina. The mechanism behind this effect is poorly understood. We set out to investigate whether exercise-induced hyperlactatemia may alter the response of retinal blood flow to hyperglycemia. We performed a randomized, controlled two-way cross over study comprising 12 healthy subjects, performed a 6-minutes period of dynamic exercise during an euglcaemic or hyperglycaemic insulin clamp. Retinal blood flow was assessed by combined vessel size measurement with the Zeiss retinal vessel analyzer and measurement of red blood cell velocities using bi-directional laser Doppler velocimetry. Retinal and systemic hemodynamic parameters were measured before, immediately after and 10 and 20 minutes after isometric exercise. On the euglycemic study day retinal blood flow increased after dynamic exercise. The maximum increase in retinal blood flow was observed 10 minutes after the end of exercise when lactate plasma concentration peaked. Hyperglycemia increased retinal blood flow under basal conditions, but had no incremental effect during exercise induced hyperlactatemia. Our results indicate that both lactate and glucose induce an increase in retinal blood flow in healthy humans. This may indicate a common pathway between glucose and lactate induced blood flow changes in the human retina.

  15. A Generic Framework for Real-Time Multi-Channel Neuronal Signal Analysis, Telemetry Control, and Sub-Millisecond Latency Feedback Generation

    PubMed Central

    Zrenner, Christoph; Eytan, Danny; Wallach, Avner; Thier, Peter; Marom, Shimon

    2010-01-01

    Distinct modules of the neural circuitry interact with each other and (through the motor-sensory loop) with the environment, forming a complex dynamic system. Neuro-prosthetic devices seeking to modulate or restore CNS function need to interact with the information flow at the level of neural modules electrically, bi-directionally and in real-time. A set of freely available generic tools is presented that allow computationally demanding multi-channel short-latency bi-directional interactions to be realized in in vivo and in vitro preparations using standard PC data acquisition and processing hardware and software (Mathworks Matlab and Simulink). A commercially available 60-channel extracellular multi-electrode recording and stimulation set-up connected to an ex vivo developing cortical neuronal culture is used as a model system to validate the method. We demonstrate how complex high-bandwidth (>10 MBit/s) neural recording data can be analyzed in real-time while simultaneously generating specific complex electrical stimulation feedback with deterministically timed responses at sub-millisecond resolution. PMID:21060803

  16. Variability of electromagnetic signatures of lightning initiation observed in the West Mediterranean basin

    NASA Astrophysics Data System (ADS)

    Kolmasova, I.; Santolik, O.; Defer, E.; Stéphane, P.; Lan, R.; Uhlir, L.; Coquillat, S.; Lambert, D.; Pinty, J. P.; Prieur, S.

    2016-12-01

    Lightning discharges to ground often exhibit millisecond-scale surges in the continuing currents following return strokes, called M-components. Relatively little is known regarding the source of M-component charge and the mechanisms by which that charge is transferred to ground. In this work, we seek to directly address these questions by presenting correlated high-speed video and Lightning Mapping Array (LMA) observations of a bi-directional leader that resulted in an M-component occurring in a rocket-and-wire triggered lightning flash. The observed leader initiated in the decayed remnants of a positive leader channel that had traversed virgin air approximately 90 msec prior. Three-dimensional locations and speeds of the photographed bi-directional leader and M-component processes are calculated by mapping video images to the observed LMA channel geometry. Both ends of the bi-directional leader exhibited speeds on the order of 2 x106 m sec-1 over 570 meters of the visible channel. Propagation of the luminosity wave from the in-cloud leader to ground ( 8.8 km channel length) exhibited appreciable dispersion, with rise-times (10-90%) increasing from 330 to 410 μsec and pulse-widths (half-maximum) increasing from 380 to 810 μsec - the M-component current pulse measured at ground-level exhibited a rise-time of 290 μsec and a pulse-width of 770 μsec. Group velocities of the luminosity wave have been calculated as a function of frequency, increasing from 2 x107 to 6 x107 m sec-1 over the dominant signal bandwidth (DC to 2 kHz). Additionally, multiple waves of luminosity are observed within the in-cloud channel, indicating nuanced wave phenomena possibly associated with reflection from the end of the leader channel and attachment with the main lightning channel carrying continuing current to ground.

  17. What about OMT and nutrition for managing the irritable bowel syndrome? An overview and treatment plan.

    PubMed

    Collebrusco, Luca; Lombardini, Rita

    2014-01-01

    A chronic continuous or intermittent gastrointestinal tract dysfunction, the irritable bowel syndrome (IBS), appears to be due to dysregulation of brain-gut-microbiota communication. Furthermore, the "microbiota" greatly impacts the bi-directional brain-gut axis communication. This article describes IBS in relation to similar diseases, presents the background to osteopathy, and proposes osteopathic manipulative treatment (OMT) to manage IBS. In IBS, OMT focuses on the nervous and circulatory systems, spine, viscera, and thoracic and pelvic diaphragms in order to restore homeostatic balance, normalize autonomic activity in the intestine, promote lymphatic flow, and address somatic dysfunction. Lymphatic and venous congestion are treated by the lymphatic pump techniques and stimulation of Chapman׳s reflex points. A simple treatment plan designed to lessen chronic pain and inflammation in IBS is presented based on current evidence-based literature. Since food itself, food allergies, and intolerance could contribute to symptom onset or even cause IBS, this article also provides dietary modifications to consider for patients. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Does Helping Keep Teens Protected? Longitudinal Bidirectional Relations Between Prosocial Behavior and Problem Behavior.

    PubMed

    Padilla-Walker, Laura M; Carlo, Gustavo; Nielson, Matthew G

    2015-01-01

    The current study examined bidirectional, longitudinal links between prosocial and problem behavior. Participants (N = 500) were recruited from a Northwestern city in the United States and assessed for 3 consecutive years from 2009 to 2011 (M(age) of youth at Time 1 = 13.32, SD = 1.05; 52% girls; 67% European American, 33% single-parent families). Results suggested that effects of earlier prosocial behavior toward family and strangers were predictive of fewer problem behaviors 2 years later, while results for prosocial behavior toward friends were more mixed. Results also suggested depression predicted lower prosocial behavior toward family members and anxiety predicted higher prosocial behavior toward friends. Findings show a complex pattern of relations that demonstrate the need to consider targets of helping. © 2015 The Authors. Child Development © 2015 Society for Research in Child Development, Inc.

  19. A Statistical Theory of Bidirectionality

    NASA Technical Reports Server (NTRS)

    DeLoach, Richard; Ulbrich, Norbert

    2013-01-01

    Original concepts related to the quantification and assessment of bidirectionality in strain-gage balances were introduced by Ulbrich in 2012. These concepts are extended here in three ways: 1) the metric originally proposed by Ulbrich is normalized, 2) a categorical variable is introduced in the regression analysis to account for load polarity, and 3) the uncertainty in both normalized and non-normalized bidirectionality metrics is quantified. These extensions are applied to four representative balances to assess the bidirectionality characteristics of each. The paper is tutorial in nature, featuring reviews of certain elements of regression and formal inference. Principal findings are that bidirectionality appears to be a common characteristic of most balance outputs and that unless it is taken into account, it is likely to consume the entire error budget of a typical balance calibration experiment. Data volume and correlation among calibration loads are shown to have a significant impact on the precision with which bidirectionality metrics can be assessed.

  20. Optical Correlation Techniques In Fluid Dynamics

    NASA Astrophysics Data System (ADS)

    Schatzel, K.; Schulz-DuBois, E. O.; Vehrenkamp, R.

    1981-05-01

    Three flow measurement techniques make use of fast digital correlators. (1) Most widely spread is photon correlation velocimetry using crossed laser beams and detecting Doppler shifted light scattered by small particles in the flow. Depending on the processing of the photon correlogram, this technique yields mean velocity, turbulence level, or even the detailed probability distribution of one velocity component. An improved data processing scheme is demonstrated on laminar vortex flow in a curved channel. (2) Rate correlation based upon threshold crossings of a high pass filtered laser Doppler signal can he used to obtain velocity correlation functions. The most powerful setup developed in our laboratory uses a phase locked loop type tracker and a multibit correlator to analyse time-dependent Taylor vortex flow. With two optical systems and trackers, crosscorrelation functions reveal phase relations between different vortices. (3) Making use of refractive index fluctuations (e. g. in two phase flows) instead of scattering particles, interferometry with bidirectional fringe counting and digital correlation and probability analysis constitute a new quantitative technique related to classical Schlieren methods. Measurements on a mixing flow of heated and cold air contribute new ideas to the theory of turbulent random phase screens.

  1. Optical correlation techniques in fluid dynamics

    NASA Astrophysics Data System (ADS)

    Schätzel, K.; Schulz-Dubois, E. O.; Vehrenkamp, R.

    1981-04-01

    Three flow measurement techniques make use of fast digital correlators. The most widely spread is photon correlation velocimetry using crossed laser beams, and detecting Doppler shifted light scattered by small particles in the flow. Depending on the processing of the photon correlation output, this technique yields mean velocity, turbulence level, and even the detailed probability distribution of one velocity component. An improved data processing scheme is demonstrated on laminar vortex flow in a curved channel. In the second method, rate correlation based upon threshold crossings of a high pass filtered laser Doppler signal can be used to obtain velocity correlation functions. The most powerful set-up developed in our laboratory uses a phase locked loop type tracker and a multibit correlator to analyze time-dependent Taylor vortex flow. With two optical systems and trackers, cross-correlation functions reveal phase relations between different vortices. The last method makes use of refractive index fluctuations (eg in two phase flows) instead of scattering particles. Interferometry with bidirectional counting, and digital correlation and probability analysis, constitutes a new quantitative technique related to classical Schlieren methods. Measurements on a mixing flow of heated and cold air contribute new ideas to the theory of turbulent random phase screens.

  2. A Bidirectional Brain-Machine Interface Algorithm That Approximates Arbitrary Force-Fields

    PubMed Central

    Semprini, Marianna; Mussa-Ivaldi, Ferdinando A.; Panzeri, Stefano

    2014-01-01

    We examine bidirectional brain-machine interfaces that control external devices in a closed loop by decoding motor cortical activity to command the device and by encoding the state of the device by delivering electrical stimuli to sensory areas. Although it is possible to design this artificial sensory-motor interaction while maintaining two independent channels of communication, here we propose a rule that closes the loop between flows of sensory and motor information in a way that approximates a desired dynamical policy expressed as a field of forces acting upon the controlled external device. We previously developed a first implementation of this approach based on linear decoding of neural activity recorded from the motor cortex into a set of forces (a force field) applied to a point mass, and on encoding of position of the point mass into patterns of electrical stimuli delivered to somatosensory areas. However, this previous algorithm had the limitation that it only worked in situations when the position-to-force map to be implemented is invertible. Here we overcome this limitation by developing a new non-linear form of the bidirectional interface that can approximate a virtually unlimited family of continuous fields. The new algorithm bases both the encoding of position information and the decoding of motor cortical activity on an explicit map between spike trains and the state space of the device computed with Multi-Dimensional-Scaling. We present a detailed computational analysis of the performance of the interface and a validation of its robustness by using synthetic neural responses in a simulated sensory-motor loop. PMID:24626393

  3. Concomitant bidirectional transport during peritoneal dialysis can be explained by a structured interstitium

    PubMed Central

    Waniewski, Jacek; Flessner, Michael F.; Lindholm, Bengt

    2016-01-01

    Clinical and animal studies suggest that peritoneal absorption of fluid and protein from dialysate to peritoneal tissue, and to blood and lymph circulation, occurs concomitantly with opposite flows of fluid and protein, i.e., from blood to dialysate. However, until now a theoretical explanation of this phenomenon has been lacking. A two-phase distributed model is proposed to explain the bidirectional, concomitant transport of fluid, albumin and glucose through the peritoneal transport system (PTS) during peritoneal dialysis. The interstitium of this tissue is described as an expandable two-phase structure with phase F (water-rich, colloid-poor region) and phase C (water-poor, colloid-rich region) with fluid and solute exchange between them. A low fraction of phase F is assumed in the intact tissue, which can be significantly increased under the influence of hydrostatic pressure and tissue hydration. The capillary wall is described using the three-pore model, and the conditions in the peritoneal cavity are assumed commencing 3 min after the infusion of glucose 3.86% dialysis fluid. Computer simulations demonstrate that peritoneal absorption of fluid into the tissue, which occurs via phase F at the rate of 1.8 ml/min, increases substantially the interstitial pressure and tissue hydration in both phases close to the peritoneal cavity, whereas the glucose-induced ultrafiltration from blood occurs via phase C at the rate of 15 ml/min. The proposed model delineating the phenomenon of concomitant bidirectional transport through PTS is based on a two-phase structure of the interstitium and provides results in agreement with clinical and experimental data. PMID:26945084

  4. Electron magnetic reconnection without ion coupling in Earth's turbulent magnetosheath

    NASA Astrophysics Data System (ADS)

    Phan, T. D.; Eastwood, J. P.; Shay, M. A.; Drake, J. F.; Sonnerup, B. U. Ö.; Fujimoto, M.; Cassak, P. A.; Øieroset, M.; Burch, J. L.; Torbert, R. B.; Rager, A. C.; Dorelli, J. C.; Gershman, D. J.; Pollock, C.; Pyakurel, P. S.; Haggerty, C. C.; Khotyaintsev, Y.; Lavraud, B.; Saito, Y.; Oka, M.; Ergun, R. E.; Retino, A.; Le Contel, O.; Argall, M. R.; Giles, B. L.; Moore, T. E.; Wilder, F. D.; Strangeway, R. J.; Russell, C. T.; Lindqvist, P. A.; Magnes, W.

    2018-05-01

    Magnetic reconnection in current sheets is a magnetic-to-particle energy conversion process that is fundamental to many space and laboratory plasma systems. In the standard model of reconnection, this process occurs in a minuscule electron-scale diffusion region1,2. On larger scales, ions couple to the newly reconnected magnetic-field lines and are ejected away from the diffusion region in the form of bi-directional ion jets at the ion Alfvén speed3-5. Much of the energy conversion occurs in spatially extended ion exhausts downstream of the diffusion region6. In turbulent plasmas, which contain a large number of small-scale current sheets, reconnection has long been suggested to have a major role in the dissipation of turbulent energy at kinetic scales7-11. However, evidence for reconnection plasma jetting in small-scale turbulent plasmas has so far been lacking. Here we report observations made in Earth's turbulent magnetosheath region (downstream of the bow shock) of an electron-scale current sheet in which diverging bi-directional super-ion-Alfvénic electron jets, parallel electric fields and enhanced magnetic-to-particle energy conversion were detected. Contrary to the standard model of reconnection, the thin reconnecting current sheet was not embedded in a wider ion-scale current layer and no ion jets were detected. Observations of this and other similar, but unidirectional, electron jet events without signatures of ion reconnection reveal a form of reconnection that can drive turbulent energy transfer and dissipation in electron-scale current sheets without ion coupling.

  5. Electron magnetic reconnection without ion coupling in Earth's turbulent magnetosheath.

    PubMed

    Phan, T D; Eastwood, J P; Shay, M A; Drake, J F; Sonnerup, B U Ö; Fujimoto, M; Cassak, P A; Øieroset, M; Burch, J L; Torbert, R B; Rager, A C; Dorelli, J C; Gershman, D J; Pollock, C; Pyakurel, P S; Haggerty, C C; Khotyaintsev, Y; Lavraud, B; Saito, Y; Oka, M; Ergun, R E; Retino, A; Le Contel, O; Argall, M R; Giles, B L; Moore, T E; Wilder, F D; Strangeway, R J; Russell, C T; Lindqvist, P A; Magnes, W

    2018-05-01

    Magnetic reconnection in current sheets is a magnetic-to-particle energy conversion process that is fundamental to many space and laboratory plasma systems. In the standard model of reconnection, this process occurs in a minuscule electron-scale diffusion region 1,2 . On larger scales, ions couple to the newly reconnected magnetic-field lines and are ejected away from the diffusion region in the form of bi-directional ion jets at the ion Alfvén speed 3-5 . Much of the energy conversion occurs in spatially extended ion exhausts downstream of the diffusion region 6 . In turbulent plasmas, which contain a large number of small-scale current sheets, reconnection has long been suggested to have a major role in the dissipation of turbulent energy at kinetic scales 7-11 . However, evidence for reconnection plasma jetting in small-scale turbulent plasmas has so far been lacking. Here we report observations made in Earth's turbulent magnetosheath region (downstream of the bow shock) of an electron-scale current sheet in which diverging bi-directional super-ion-Alfvénic electron jets, parallel electric fields and enhanced magnetic-to-particle energy conversion were detected. Contrary to the standard model of reconnection, the thin reconnecting current sheet was not embedded in a wider ion-scale current layer and no ion jets were detected. Observations of this and other similar, but unidirectional, electron jet events without signatures of ion reconnection reveal a form of reconnection that can drive turbulent energy transfer and dissipation in electron-scale current sheets without ion coupling.

  6. A Fully Directional Universal Power Electronic Interface for EV, HEV, and PHEV Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Onar, Omer C

    2012-01-01

    This study focuses on a universal power electronic interface that can be utilized in any type of the electric vehicles, hybrid electric vehicles, and plug-in hybrid electric vehicles (PHEVs). Basically, the proposed converter interfaces the energy storage device of the vehicle with the motor drive and the external charger, in case of PHEVs. The proposed converter is capable of operating in all directions in buck or boost modes with a noninverted output voltage (positive output voltage with respect to the input) and bidirectional power flow.

  7. Bidirectional exchange of biogenic volatiles with vegetation: emission sources, reactions, breakdown and deposition

    PubMed Central

    Niinemets, Ülo; Fares, Silvano; Harley, Peter; Jardine, Kolby J.

    2014-01-01

    Biogenic volatile organic compound (BVOC) emissions are widely modeled as inputs to atmospheric chemistry simulations. However, BVOC may interact with cellular structures and neighboring leaves in a complex manner during volatile diffusion from the sites of release to leaf boundary layer and during turbulent transport to the atmospheric boundary layer. Furthermore, recent observations demonstrate that the BVOC emissions are bidirectional, and uptake and deposition of BVOC and their oxidation products are the rule rather than the exception. This review summarizes current knowledge of within-leaf reactions of synthesized volatiles with reactive oxygen species (ROS), uptake, deposition and storage of volatiles and their oxidation products as driven by adsorption on leaf surface and solubilization and enzymatic detoxification inside leaves. The available evidence indicates that due to reactions with ROS and enzymatic metabolism, the BVOC gross production rates are much larger than previously thought. The degree to which volatiles react within leaves and can be potentially taken up by vegetation depends on compound reactivity, physicochemical characteristics, as well as their participation in leaf metabolism. We argue that future models should be based on the concept of bidirectional BVOC exchange and consider modification of BVOC sink/source strengths by within-leaf metabolism and storage. PMID:24635661

  8. Reflectance Experiment Laboratory (RELAB) Description and User's Manual

    NASA Technical Reports Server (NTRS)

    Pieters, Carle M.; Hiroi, Takahiro; Pratt, Steve F.; Patterson, Bill

    2004-01-01

    Spectroscopic data acquired in the laboratory provide the interpretive foundation upon which compositional information about unexplored or unsampled planetary surfaces is derived from remotely obtained reflectance spectra. The RELAB is supported by NASA as a multi-user spectroscopy facility, and laboratory time can be made available at no charge to investigators who are in funded NASA programs. RELAB has two operational spectrometers available to NASA scientists: 1) a near- ultraviolet, visible, and near-infrared bidirectional spectrometer and 2) a near- and mid- infrared FT-IR spectrometer. The overall purpose of the design and operation of the RELAB bidirectional spectrometer is to obtain high precision, high spectral resolution, bidirectional reflectance spectra of earth and planetary materials. One of the key elements of its design is the ability to measure samples using viewing geometries specified by the user. This allows investigators to simulate, under laboratory conditions, reflectance spectra obtained remotely (i.e., with spaceborne, telescopic, and airborne systems) as well as to investigate geometry dependent reflectance properties of geologic materials. The Nicolet 740 FT-IR spectrometer currently operates in reflectance mode from 0.9 to 25 Fm. Use and scheduling of the RELAB is monitored by a 4-member advisory committee. NASA investigators should direct inquiries to the Science Manager or RELAB Operator.

  9. Reciprocal Relations between Perceived Parental Knowledge and Adolescent Substance Use and Delinquency: The Moderating Role of Parent-Teen Relationship Quality

    ERIC Educational Resources Information Center

    Abar, Caitlin C.; Jackson, Kristina M.; Wood, Mark

    2014-01-01

    The current study prospectively examined hypothesized short- and long-term reciprocal relations between perceived parental knowledge and adolescent heavy episodic drinking, marijuana use, and delinquency. Using the contextual model of parenting style (Darling & Steinberg, 1993), we examined the extent to which the bidirectional nature of…

  10. Assessment of Refueling Hose Visibility

    DTIC Science & Technology

    2012-10-01

    shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number...10 7 Basic Model of Contrast Loss through Aircraft Windscreen Due To Haze ..................... 10 8...known as a bidirectional (azimuth and elevation) reflectance distribution function or BRDF . This is extremely time-consuming and impractical. In

  11. Children's Perceived Agency in the Context of Marital Conflict: Relations with Marital Conflict over Time

    ERIC Educational Resources Information Center

    Schermerhorn, Alice C.; Cummings, E. Mark; Davies, Patrick T.

    2005-01-01

    Consistent with the bidirectional perspective on parent-child relations, the current study examined children's perceptions of agency in the context of marital conflict. A storytelling task was completed by 11 5 five-year-old children, tapping perceived agency. These children and their mothers and fathers completed measures of marital conflict at…

  12. Bi-directional Reflectance of Icy Surface Analogs: A Dual Approach

    NASA Astrophysics Data System (ADS)

    Quinones, Juan Manuel; Vides, Christina; Nelson, Robert M.; Boryta, Mark; Mannat, Ken s.

    2018-01-01

    Bi-directional reflectance measurements of analogs for planetary regolith have provided insight into the surface properties of planetary satellites and small bodies. Because Aluminum Oxide (Al2O3) and water ice share a similar hexagonal crystalline structure, the former has been used in laboratory experiments to simulate the regolith of both icy and dusty planetary bodies. By measuring various sizes of well sorted size fractions of Al2O3, the reflectance phase curve and porosity of a planetary regolith can be determined. We have designed an experiment to test the laboratory measurements produced by Nelson et al. (2000). Additionally, we made reflectance measurements for other alkali-halide compounds that could be used for applications beyond astronomy and planetary science.In order to provide an independent check on the Nelson et al. data, we designed an instrument with a different configuration. While both instruments take bidirectional reflectance measurements, our instrument, the Rigid Photometric Goniometer (RPG), is fixed at a phase angle of 5° and detects the scattered light with a photomultiplier tube (PMT). The PMT current is then measured with an electrometer. Following the example of Nelson et al., we measured the bidirectional reflectance of Al2O3 particulate size fractions between 0.1

  13. [Geochemical distribution of dissolved bismuth in the Yellow Sea and East China Sea].

    PubMed

    Wu, Xiao-Dan; Song, Jin-Ming; Wu, Bin; Li, Xue-Gang

    2014-01-01

    Occurrence level, geochemical distribution of dissolved bismuth and its coupling relationship to eco-environment were investigated in the Yellow Sea and East China Sea to explore the source and influencing factors. The results showed that the concentration of dissolved bismuth was within the range of 0-0. 029 microg x L(-1) at the surface and 0.001-0.189 microg x L(-1) at the bottom, with the averages of 0.008 and 0.016 microg x L(-1), respectively. Horizontally, low value of dissolved bismuth exhibited the bidirectional extension feature, indicating that it could trace the path of Changjiang Diluted Water. High value of dissolved bismuth was observed where the Subei Costal Current and Yellow Sea Warm Current flowed and the Changjiang Diluted Water and Zhejiang-Fujian Coastal Current met, suggesting that it was controlled by the cycle of current system. Vertically, the coastal water was fully mixed by water convection and eddy mixing, and was divided from the stratified water by strong tidal front, which blocked the transport of dissolved bismuth to the open sea. Thus, the concentration in front area was significantly higher than that in the open sea. Diurnal variation of dissolved bismuth was related to the hydrodynamic conditions (tide, suspension and thermocline) instead of the environmental factors (temperature and salinity). Positive relationship to SPM (suspended particulate matter) clarified that bismuth was prone to release from solid phase to liquid phase. Furthermore, conditions with temperature ranging 22-27 degrees C, salinity ranging 28-31 and pH ranging 7.9-8.1 were shown to be optimal for the release process.

  14. Enhanced robustness of evolving open systems by the bidirectionality of interactions between elements.

    PubMed

    Ogushi, Fumiko; Kertész, János; Kaski, Kimmo; Shimada, Takashi

    2017-08-01

    Living organisms, ecosystems, and social systems are examples of complex systems in which robustness against inclusion of new elements is an essential feature. A recently proposed simple model has revealed a general mechanism by which such systems can become robust against inclusion of elements with totally random interactions when the elements have a moderate number of links. The interaction is, however, in many systems often intrinsically bidirectional like for mutual symbiosis and competition in ecology. This study reports the strong reinforcement effect of the bidirectionality of the interactions on the robustness of evolving systems. We show that the system with purely bidirectional interactions can grow with twofold average degree, in comparison with the purely unidirectional system. This drastic shift of the transition point comes from the reinforcement of each node, not from a change in structure of the emergent system. For systems with partially bidirectional interactions we find that the regime of the growing phase gets expanded. In the dense interaction regime, there exists an optimum proportion of bidirectional interactions for the growth rate at around 1/3. In the sparsely connected systems, small but finite fraction of bidirectional links can change the system's behaviour from non-growing to growing.

  15. Fail-safe bidirectional valve driver

    NASA Technical Reports Server (NTRS)

    Fujimoto, H.

    1974-01-01

    Cross-coupled diodes are added to commonly used bidirectional valve driver circuit to protect circuit and power supply. Circuit may be used in systems requiring fail-safe bidirectional valve operation, particularly in chemical- and petroleum-processing control systems and computer-controlled hydraulic or pneumatic systems.

  16. Jamming transitions induced by an attraction in pedestrian flow.

    PubMed

    Kwak, Jaeyoung; Jo, Hang-Hyun; Luttinen, Tapio; Kosonen, Iisakki

    2017-08-01

    We numerically study jamming transitions in pedestrian flow interacting with an attraction, mostly based on the social force model for pedestrians who can join the attraction. We formulate the joining probability as a function of social influence from others, reflecting that individual choice behavior is likely influenced by others. By controlling pedestrian influx and the social influence parameter, we identify various pedestrian flow patterns. For the bidirectional flow scenario, we observe a transition from the free flow phase to the freezing phase, in which oppositely walking pedestrians reach a complete stop and block each other. On the other hand, a different transition behavior appears in the unidirectional flow scenario, i.e., from the free flow phase to the localized jam phase and then to the extended jam phase. It is also observed that the extended jam phase can end up in freezing phenomena with a certain probability when pedestrian flux is high with strong social influence. This study highlights that attractive interactions between pedestrians and an attraction can trigger jamming transitions by increasing the number of conflicts among pedestrians near the attraction. In order to avoid excessive pedestrian jams, we suggest suppressing the number of conflicts under a certain level by moderating pedestrian influx especially when the social influence is strong.

  17. Jamming transitions induced by an attraction in pedestrian flow

    NASA Astrophysics Data System (ADS)

    Kwak, Jaeyoung; Jo, Hang-Hyun; Luttinen, Tapio; Kosonen, Iisakki

    2017-08-01

    We numerically study jamming transitions in pedestrian flow interacting with an attraction, mostly based on the social force model for pedestrians who can join the attraction. We formulate the joining probability as a function of social influence from others, reflecting that individual choice behavior is likely influenced by others. By controlling pedestrian influx and the social influence parameter, we identify various pedestrian flow patterns. For the bidirectional flow scenario, we observe a transition from the free flow phase to the freezing phase, in which oppositely walking pedestrians reach a complete stop and block each other. On the other hand, a different transition behavior appears in the unidirectional flow scenario, i.e., from the free flow phase to the localized jam phase and then to the extended jam phase. It is also observed that the extended jam phase can end up in freezing phenomena with a certain probability when pedestrian flux is high with strong social influence. This study highlights that attractive interactions between pedestrians and an attraction can trigger jamming transitions by increasing the number of conflicts among pedestrians near the attraction. In order to avoid excessive pedestrian jams, we suggest suppressing the number of conflicts under a certain level by moderating pedestrian influx especially when the social influence is strong.

  18. An Asymptotically-Optimal Sampling-Based Algorithm for Bi-directional Motion Planning

    PubMed Central

    Starek, Joseph A.; Gomez, Javier V.; Schmerling, Edward; Janson, Lucas; Moreno, Luis; Pavone, Marco

    2015-01-01

    Bi-directional search is a widely used strategy to increase the success and convergence rates of sampling-based motion planning algorithms. Yet, few results are available that merge both bi-directional search and asymptotic optimality into existing optimal planners, such as PRM*, RRT*, and FMT*. The objective of this paper is to fill this gap. Specifically, this paper presents a bi-directional, sampling-based, asymptotically-optimal algorithm named Bi-directional FMT* (BFMT*) that extends the Fast Marching Tree (FMT*) algorithm to bidirectional search while preserving its key properties, chiefly lazy search and asymptotic optimality through convergence in probability. BFMT* performs a two-source, lazy dynamic programming recursion over a set of randomly-drawn samples, correspondingly generating two search trees: one in cost-to-come space from the initial configuration and another in cost-to-go space from the goal configuration. Numerical experiments illustrate the advantages of BFMT* over its unidirectional counterpart, as well as a number of other state-of-the-art planners. PMID:27004130

  19. Bidirectional Associations between Parenting Practices and Conduct Problems in Boys from Childhood to Adolescence: The Moderating Effect of Age and African-American Ethnicity

    PubMed Central

    Fite, Paula J.; Burke, Jeffrey D.

    2010-01-01

    This study examined the bidirectional relationship between parent and teacher reported conduct problems in youth and parenting practices using a longitudinal sample of boys assessed from 6 to 16 years of age. Analyses tested whether these bidirectional associations changed across development and whether the nature of these associations varied across African-American and Caucasian families. Overall, the results supported a bidirectional relationship between conduct problems and all parenting practices examined from childhood to adolescence. The influence of conduct problems on changes in parenting behaviors was as strong as the influence of parenting behaviors on changes in conduct problems across development. Changes in the bidirectional relationship across development were found in some, but not all, models. While corporal punishment was more strongly related to changes in teacher-reported conduct problems for African-American boys compared to Caucasian boys, more similarities than differences were found between the ethnic groups in terms of the bidirectional associations examined. PMID:17899362

  20. Bi-directional four quadrant (BDQ4) power converter development

    NASA Technical Reports Server (NTRS)

    Schwarz, F. C.

    1979-01-01

    The feasibility for implementation of a concept for direct ac/dc multikilowatt power conversion with bidirectional transfer of energy was investigated. A 10 kHz current carrier was derived directly from a common 60 Hz three phase power system. This carrier was modulated to remove the 360 Hz ripple, inherent in the three phase power supply and then demodulated and processed by a high frequency filter. The resulting dc power was then supplied to a load. The process was implemented without the use of low frequency transformers and filters. This power conversion processes was reversible and can operate in the four quadrants as viewed from any of the two of the converter's ports. Areas of application include: power systems on air and spacecraft; terrestrial traction; integration of solar and wind powered systems with utility networks; HVDC; asynchronous coupling of polyphase networks; heat treatment; industrial machine drives; and power supplies for any use including instrumentation.

  1. Executive function predicts artificial language learning

    PubMed Central

    Kapa, Leah L.; Colombo, John

    2017-01-01

    Previous research suggests executive function (EF) advantages among bilinguals compared to monolingual peers, and these advantages are generally attributed to experience controlling two linguistic systems. However, the possibility that the relationship between bilingualism and EF might be bidirectional has not been widely considered; while experience with two languages might improve EF, better EF skills might also facilitate language learning. In the current studies, we tested whether adults’ and preschool children’s EF abilities predicted success in learning a novel artificial language. After controlling for working memory and English receptive vocabulary, adults’ artificial language performance was predicted by their inhibitory control ability (Study 1) and children’s performance was predicted by their attentional monitoring and shifting ability (Study 2). These findings provide preliminary evidence suggesting that EF processes may be employed during initial stages of language learning, particularly vocabulary acquisition, and support the possibility of a bidirectional relationship between EF and language acquisition. PMID:29129958

  2. Performance Assessment of Bi-Directional Knotless Tissue-Closure Devices in Juvenile Chinook Salmon Surgically Implanted with Acoustic Transmitters, 2009 - Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woodley, Christa M.; Wagner, Katie A.; Bryson, Amanda J.

    2012-11-09

    The purpose of this report is to assess the performance of bi-directional knotless tissue-closure devices for use in tagging juvenile salmon. This study is part of an ongoing effort at Pacific Northwest National Laboratory (PNNL) to reduce unwanted effects of tags and tagging procedures on the survival and behavior of juvenile salmonids, by assessing and refining suturing techniques, suture materials, and tag burdens. The objective of this study was to compare the performance of the knotless (barbed) suture, using three different suture patterns (treatments: 6-point, Wide “N”, Wide “N” Knot), to the current method of suturing (MonocrylTM monofilament, discontinuous suturesmore » with a 2×2×2×2 knot) used in monitoring and research programs with a novel antiseptic barrier on the wound (“Second Skin”).« less

  3. Detecting the existence of gene flow between Spanish and North African goats through a coalescent approach.

    PubMed

    Martínez, Amparo; Manunza, Arianna; Delgado, Juan Vicente; Landi, Vincenzo; Adebambo, Ayotunde; Ismaila, Muritala; Capote, Juan; El Ouni, Mabrouk; Elbeltagy, Ahmed; Abushady, Asmaa M; Galal, Salah; Ferrando, Ainhoa; Gómez, Mariano; Pons, Agueda; Badaoui, Bouabid; Jordana, Jordi; Vidal, Oriol; Amills, Marcel

    2016-12-14

    Human-driven migrations are one of the main processes shaping the genetic diversity and population structure of domestic species. However, their magnitude and direction have been rarely analysed in a statistical framework. We aimed to estimate the impact of migration on the population structure of Spanish and African goats. To achieve this goal, we analysed a dataset of 1,472 individuals typed with 23 microsatellites. Population structure of African and Spanish goats was moderate (mean F ST  = 0.07), with the exception of the Canarian and South African breeds that displayed a significant differentiation when compared to goats from North Africa and Nigeria. Measurement of gene flow with Migrate-n and IMa coalescent genealogy samplers supported the existence of a bidirectional gene flow between African and Spanish goats. Moreover, IMa estimates of the effective number of migrants were remarkably lower than those calculated with Migrate-n and classical approaches. Such discrepancies suggest that recent divergence, rather than extensive gene flow, is the main cause of the weak population structure observed in caprine breeds.

  4. Detecting the existence of gene flow between Spanish and North African goats through a coalescent approach

    PubMed Central

    Martínez, Amparo; Manunza, Arianna; Delgado, Juan Vicente; Landi, Vincenzo; Adebambo, Ayotunde; Ismaila, Muritala; Capote, Juan; El Ouni, Mabrouk; Elbeltagy, Ahmed; Abushady, Asmaa M.; Galal, Salah; Ferrando, Ainhoa; Gómez, Mariano; Pons, Agueda; Badaoui, Bouabid; Jordana, Jordi; Vidal, Oriol; Amills, Marcel

    2016-01-01

    Human-driven migrations are one of the main processes shaping the genetic diversity and population structure of domestic species. However, their magnitude and direction have been rarely analysed in a statistical framework. We aimed to estimate the impact of migration on the population structure of Spanish and African goats. To achieve this goal, we analysed a dataset of 1,472 individuals typed with 23 microsatellites. Population structure of African and Spanish goats was moderate (mean FST = 0.07), with the exception of the Canarian and South African breeds that displayed a significant differentiation when compared to goats from North Africa and Nigeria. Measurement of gene flow with Migrate-n and IMa coalescent genealogy samplers supported the existence of a bidirectional gene flow between African and Spanish goats. Moreover, IMa estimates of the effective number of migrants were remarkably lower than those calculated with Migrate-n and classical approaches. Such discrepancies suggest that recent divergence, rather than extensive gene flow, is the main cause of the weak population structure observed in caprine breeds. PMID:27966592

  5. Transcranial current stimulation focality using disc and ring electrode configurations: FEM analysis

    NASA Astrophysics Data System (ADS)

    Datta, Abhishek; Elwassif, Maged; Battaglia, Fortunato; Bikson, Marom

    2008-06-01

    We calculated the electric fields induced in the brain during transcranial current stimulation (TCS) using a finite-element concentric spheres human head model. A range of disc electrode configurations were simulated: (1) distant-bipolar; (2) adjacent-bipolar; (3) tripolar; and three ring designs, (4) belt, (5) concentric ring, and (6) double concentric ring. We compared the focality of each configuration targeting cortical structures oriented normal to the surface ('surface-radial' and 'cross-section radial'), cortical structures oriented along the brain surface ('surface-tangential' and 'cross-section tangential') and non-oriented cortical surface structures ('surface-magnitude' and 'cross-section magnitude'). For surface-radial fields, we further considered the 'polarity' of modulation (e.g. superficial cortical neuron soma hyper/depolarizing). The distant-bipolar configuration, which is comparable with commonly used TCS protocols, resulted in diffuse (un-focal) modulation with bi-directional radial modulation under each electrode and tangential modulation between electrodes. Increasing the proximity of the two electrodes (adjacent-bipolar electrode configuration) increased focality, at the cost of more surface current. At similar electrode distances, the tripolar-electrodes configuration produced comparable peak focality, but reduced radial bi-directionality. The concentric-ring configuration resulted in the highest spatial focality and uni-directional radial modulation, at the expense of increased total surface current. Changing ring dimensions, or use of two concentric rings, allow titration of this balance. The concentric-ring design may thus provide an optimized configuration for targeted modulation of superficial cortical neurons.

  6. Biomimetic Bidirectional Switchable Adhesive Inspired by the Gecko

    DTIC Science & Technology

    2014-01-01

    structures, [ 24 ] and the resulting gecko-like surface was reminiscent of the tribological properties of gecko pads. With our current design, the...rely on intensive nanofabrication in order to recover the anisotropic tribological property of gecko adhesive pads, albeit with lower adhesive forces...Naval Research Laboratory Washington , D.C. 20375 , USA Dr. Y. Tian State Key Laboratory of Tribology Tsinghua University Beijing

  7. Linear induction accelerators made from pulse-line cavities with external pulse injection.

    PubMed

    Smith, I

    1979-06-01

    Two types of linear induction accelerator have been reported previously. In one, unidirectional voltage pulses are generated outside the accelerator and injected into the accelerator cavity modules, which contain ferromagnetic material to reduce energy losses in the form of currents induced, in parallel with the beam, in the cavity structure. In the other type, the accelerator cavity modules are themselves pulse-forming lines with energy storage and switches; parallel current losses are made zero by the use of circuits that generate bidirectional acceleration waveforms with a zero voltage-time integral. In a third type of design described here, the cavities are externally driven, and 100% efficient coupling of energy to the beam is obtained by designing the external pulse generators to produce bidirectional voltage waveforms with zero voltage-time integral. A design for such a pulse generator is described that is itself one hundred percent efficient and which is well suited to existing pulse power techniques. Two accelerator cavity designs are described that can couple the pulse from such a generator to the beam; one of these designs provides voltage doubling. Comparison is made between the accelerating gradients that can be obtained with this and the preceding types of induction accelerator.

  8. Reproductive traits and evolutionary divergence between Mediterranean crops and their wild relatives.

    PubMed

    Iriondo, J M; Milla, R; Volis, S; Rubio de Casas, R

    2018-01-01

    Changes in reproductive traits associated with domestication critically determine the evolutionary divergence between crops and their wild relatives, as well as the potential of crop plants to become feral. In this review, we examine the genetic mechanisms of plant domestication and the different types of selection involved, and describe the particularities of domestication of Mediterranean field crops with regard to their reproductive traits, showing illustrative examples. We also explore gene flow patterns between Mediterranean field crops and their wild relatives, along with their ecological, evolutionary and economic implications. Domestication entails multiple selective processes, including direct selection, environmental adaptation and developmental constraints. In contrast to clonal propagation in perennials, sexual reproduction and seed propagation in annuals and biennials have led to a distinct pathway of evolution of reproductive traits. Thus, the initial domestication and further breeding of Mediterranean field crops has brought about changes in reproductive traits, such as higher mean values and variance of seed and fruit sizes, reduced fruit and seed toxicity, non-shattering seeds and loss of seed dormancy. Evolution under domestication is not a linear process, and bi-directional gene flow between wild and crop taxa is a frequent phenomenon. Thus, hybridisation and introgression have played a very important role in determining the genetics of current cultivars. In turn, gene flow from crops to wild relatives can lead to introgression of crop genes into wild populations and potentially alter the characteristics of natural communities. In conclusion, plant evolution under domestication has not only changed the reproductive biology of cultivated taxa, its effects are multifaceted and have implications beyond agriculture. © 2017 German Society for Plant Sciences and The Royal Botanical Society of the Netherlands.

  9. Global evaluation of ammonia bidirectional exchange and livestock diurnal variation schemes

    EPA Science Inventory

    Bidirectional air–surface exchange of ammonia (NH3) has been neglected in many air quality models. In this study, we implement the bidirectional exchange of NH3 in the GEOS-Chem global chemical transport model. We also introduce an updated diurnal variability scheme for NH3...

  10. Computer-Communications Networks and Teletraffic.

    ERIC Educational Resources Information Center

    Switzer, I.

    Bi-directional cable TV (CATV) systems that are being installed today may not be well suited for computer communications. Older CATV systems are being modified to bi-directional transmission and most new systems are being built with bi-directional capability included. The extreme bandwidth requirement for carrying 20 or more TV channels on a…

  11. Evolution of bidirectional sex change and gonochorism in fishes of the gobiid genera Trimma, Priolepis, and Trimmatom.

    PubMed

    Sunobe, Tomoki; Sado, Tetsuya; Hagiwara, Kiyoshi; Manabe, Hisaya; Suzuki, Toshiyuki; Kobayashi, Yasuhisa; Sakurai, Makoto; Dewa, Shin-Ichi; Matsuoka, Midori; Shinomiya, Akihiko; Fukuda, Kazuya; Miya, Masaki

    2017-04-01

    Size-advantage and low-density models have been used to explain how mating systems favor hermaphroditism or gonochorism. However, these models do not indicate historical transitions in sexuality. Here, we investigate the evolution of bidirectional sex change and gonochorism by phylogenetic analysis using the mitochondrial gene of the gobiids Trimma (31 species), Priolepis (eight species), and Trimmatom (two species). Trimma and Priolepis formed a clade within the sister group Trimmatom. Gonadal histology and rearing experiments revealed that Trimma marinae, Trimma nasa, and Trimmatom spp. were gonochoric, whereas all other Trimma and Priolepis spp. were bidirectional sex changers or inferred ones. A maximum-likelihood reconstruction analysis demonstrated that the common ancestor of the three genera was gonochoristic. Bidirectional sex change probably evolved from gonochorism in a common ancestor of Trimma and Priolepis. As the gonads of bidirectional sex changers simultaneously contain mature ovarian and immature testicular components or vice versa, individuals are always potentially capable of functioning as females or males, respectively. Monogamy under low-density conditions may have been the ecological condition for the evolution of bidirectional sex change in a common ancestor. As T. marinae and T. nasa are a monophyletic group, gonochorism should have evolved from bidirectional sex change in a common ancestor.

  12. Evolution of bidirectional sex change and gonochorism in fishes of the gobiid genera Trimma, Priolepis, and Trimmatom

    NASA Astrophysics Data System (ADS)

    Sunobe, Tomoki; Sado, Tetsuya; Hagiwara, Kiyoshi; Manabe, Hisaya; Suzuki, Toshiyuki; Kobayashi, Yasuhisa; Sakurai, Makoto; Dewa, Shin-ichi; Matsuoka, Midori; Shinomiya, Akihiko; Fukuda, Kazuya; Miya, Masaki

    2017-04-01

    Size-advantage and low-density models have been used to explain how mating systems favor hermaphroditism or gonochorism. However, these models do not indicate historical transitions in sexuality. Here, we investigate the evolution of bidirectional sex change and gonochorism by phylogenetic analysis using the mitochondrial gene of the gobiids Trimma (31 species), Priolepis (eight species), and Trimmatom (two species). Trimma and Priolepis formed a clade within the sister group Trimmatom. Gonadal histology and rearing experiments revealed that Trimma marinae, Trimma nasa, and Trimmatom spp. were gonochoric, whereas all other Trimma and Priolepis spp. were bidirectional sex changers or inferred ones. A maximum-likelihood reconstruction analysis demonstrated that the common ancestor of the three genera was gonochoristic. Bidirectional sex change probably evolved from gonochorism in a common ancestor of Trimma and Priolepis. As the gonads of bidirectional sex changers simultaneously contain mature ovarian and immature testicular components or vice versa, individuals are always potentially capable of functioning as females or males, respectively. Monogamy under low-density conditions may have been the ecological condition for the evolution of bidirectional sex change in a common ancestor. As T. marinae and T. nasa are a monophyletic group, gonochorism should have evolved from bidirectional sex change in a common ancestor.

  13. A High-Pressure Bi-Directional Cycloid Rotor Flowmeter

    PubMed Central

    Liu, Shuo; Ding, Fan; Ding, Chuan; Man, Zaipeng

    2014-01-01

    The measurement of the flow rate of various liquids and gases is critical in industrial automation. Rotary positive displacement meters (rotary PD meters) are highly accurate flowmeters that are widely employed in engineering applications, especially in custody transfer operations and hydraulic control systems. This paper presents a high pressure rotary PD meter containing a pair of internal cycloid rotors. It has the advantages of concise structure, low pressure loss, high accuracy and low noise. The curve of the internal rotor is designed as an equidistant curtate epicycloid curve with the external rotor curve as its conjugate. The calculation method used to determine the displacement of the cycloid rotor flowmeter is discussed. A prototype was fabricated, and experiments were performed to confirm measurements over a flow range of 1–100 L/min with relative errors of less than ±0.5%. The pressure loss through the flowmeter was about 3 bar at a flow rate of 100 L/min. PMID:25196162

  14. Magnetohydrodynamic three-dimensional flow of viscoelastic nanofluid in the presence of nonlinear thermal radiation

    NASA Astrophysics Data System (ADS)

    Hayat, T.; Muhammad, Taseer; Alsaedi, A.; Alhuthali, M. S.

    2015-07-01

    Magnetohydrodynamic (MHD) three-dimensional flow of couple stress nanofluid in the presence of thermophoresis and Brownian motion effects is analyzed. Energy equation subject to nonlinear thermal radiation is taken into account. The flow is generated by a bidirectional stretching surface. Fluid is electrically conducting in the presence of a constant applied magnetic field. The induced magnetic field is neglected for a small magnetic Reynolds number. Mathematical formulation is performed using boundary layer analysis. Newly proposed boundary condition requiring zero nanoparticle mass flux is employed. The governing nonlinear mathematical problems are first converted into dimensionless expressions and then solved for the series solutions of velocities, temperature and nanoparticles concentration. Convergence of the constructed solutions is verified. Effects of emerging parameters on the temperature and nanoparticles concentration are plotted and discussed. Skin friction coefficients and Nusselt number are also computed and analyzed. It is found that the thermal boundary layer thickness is an increasing function of radiative effect.

  15. Impact of generalized Fourier's and Fick's laws on MHD 3D second grade nanofluid flow with variable thermal conductivity and convective heat and mass conditions

    NASA Astrophysics Data System (ADS)

    Ramzan, M.; Bilal, M.; Chung, Jae Dong; Lu, Dian Chen; Farooq, Umer

    2017-09-01

    A mathematical model has been established to study the magnetohydrodynamic second grade nanofluid flow past a bidirectional stretched surface. The flow is induced by Cattaneo-Christov thermal and concentration diffusion fluxes. Novel characteristics of Brownian motion and thermophoresis are accompanied by temperature dependent thermal conductivity and convective heat and mass boundary conditions. Apposite transformations are betrothed to transform a system of nonlinear partial differential equations to nonlinear ordinary differential equations. Analytic solutions of the obtained nonlinear system are obtained via a convergent method. Graphs are plotted to examine how velocity, temperature, and concentration distributions are affected by varied physical involved parameters. Effects of skin friction coefficients along the x- and y-direction versus various parameters are also shown through graphs and are well debated. Our findings show that velocities along both the x and y axes exhibit a decreasing trend for the Hartmann number. Moreover, temperature and concentration distributions are decreasing functions of thermal and concentration relaxation parameters.

  16. Bidirectional Brush Seals: Post-Test Analysis

    NASA Technical Reports Server (NTRS)

    Hendricks, Robert C.; Wilson, Jack; Wu, Tom Y.; Flower, Ralph; Mullen, Robert L.

    1997-01-01

    A post-test analysis of a set of inside-diameter/outside-diameter (ID/OD) bidirectional brush seals used in three-port wave rotor tests was undertaken to determine brush bristle and configuration wear, pullout, and rotor coating wear. The results suggest that sharp changes in the pressure profiles were not well reflected in bristle tip configuration patterns or wear. Also, positive-to-negative changes in axial pressure gradients appeared to have little effect on the backing plates. Although the brushes had similar porosities, they had very different unpacked arrays. This difference could explain the departure of experimental data from computational fluid dynamics flow predictions for well-packed arrays at higher pressure drops. The rotor wear led to "car-track" scars (upper and lower wear bands) with a whipped surface between the bands. Those bands may have resulted from bristle stiffening at the fence and gap plates during alternate portions of the rotor cycle. Within the bristle response range the wear surface reflected the pressure distribution effect on bristle motion. No sacrificial metallurgical data were taken. The bristles did wear, with correspondingly more wear on the ID brush configurations than on the OD configurations; the complexity in constructing the ID brush was a factor.

  17. A deterministic mathematical model for bidirectional excluded flow with Langmuir kinetics.

    PubMed

    Zarai, Yoram; Margaliot, Michael; Tuller, Tamir

    2017-01-01

    In many important cellular processes, including mRNA translation, gene transcription, phosphotransfer, and intracellular transport, biological "particles" move along some kind of "tracks". The motion of these particles can be modeled as a one-dimensional movement along an ordered sequence of sites. The biological particles (e.g., ribosomes or RNAPs) have volume and cannot surpass one another. In some cases, there is a preferred direction of movement along the track, but in general the movement may be bidirectional, and furthermore the particles may attach or detach from various regions along the tracks. We derive a new deterministic mathematical model for such transport phenomena that may be interpreted as a dynamic mean-field approximation of an important model from mechanical statistics called the asymmetric simple exclusion process (ASEP) with Langmuir kinetics. Using tools from the theory of monotone dynamical systems and contraction theory we show that the model admits a unique steady-state, and that every solution converges to this steady-state. Furthermore, we show that the model entrains (or phase locks) to periodic excitations in any of its forward, backward, attachment, or detachment rates. We demonstrate an application of this phenomenological transport model for analyzing ribosome drop off in mRNA translation.

  18. Bidirectional Longitudinal Relations between Father-Child Relationships and Chinese Children's Social Competence during Early Childhood

    ERIC Educational Resources Information Center

    Zhang, Xiao

    2013-01-01

    Using a two-year and three-wave cross-lagged design with a sample of 118 Chinese preschoolers, the present study examined bidirectional longitudinal relations between father-child relationships and children's social competence. The results of structural equation modeling showed bidirectional effects between father-child conflict and social…

  19. Numerical Modelling of a Bidirectional Long Ring Raman Fiber Laser Dynamics

    NASA Astrophysics Data System (ADS)

    Sukhanov, S. V.; Melnikov, L. A.; Mazhirina, Yu A.

    2017-11-01

    The numerical model for the simulation of the dynamics of a bidirectional long ring Raman fiber laser is proposed. The model is based on the transport equations and Courant-Isaacson-Rees method. Different regimes of a bidirectional long ring Raman fiber laser and long time-domain realizations are investigated.

  20. Analytical investigation of bidirectional ductile diaphragms in multi-span bridges

    NASA Astrophysics Data System (ADS)

    Wei, Xiaone; Bruneau, Michel

    2018-04-01

    In the AASHTO Guide Specifications for Seismic Bridge Design Provisions, ductile diaphragms are identified as Permissible Earthquake-Resisting Elements (EREs), designed to help resist seismic loads applied in the transverse direction of bridges. When adding longitudinal ductile diaphragms, a bidirectional ductile diaphragm system is created that can address seismic excitations acting along both the bridge's longitudinal and transverse axes. This paper investigates bidirectional ductile diaphragms with Buckling Restrained Braces (BRBs) in straight multi-span bridge with simply supported floating spans. The flexibility of the substructures in the transverse and longitudinal direction of the bridge is considered. Design procedures for the bidirectional ductile diaphragms are first proposed. An analytical model of the example bridge with bidirectional ductile diaphragms, designed based on the proposed methodology, is then built in SAP2000. Pushover and nonlinear time history analyses are performed on the bridge model, and corresponding results are presented. The effect of changing the longitudinal stiffness of the bidirectional ductile diaphragms in the end spans connecting to the abutment is also investigated, in order to better understand the impact on the bridge's dynamic performance.

  1. Application of acoustical methods for estimating water flow and constituent loads in Perdido Bay, Florida

    USGS Publications Warehouse

    Grubbs, J.W.; Pittman, J.R.

    1997-01-01

    Water flow and quality data were collected from December 1994 to September 1995 to evaluate variations in discharge, water quality, and chemical fluxes (loads) through Perdido Bay, Florida. Data were collected at a cross section parallel to the U.S. Highway 98 bridge. Discharges measured with an acoustic Doppler current profiler (ADCP) and computed from stage-area and velocity ratings varied roughly between + or - 10,000 cubic feet per second during a typical tidal cycle. Large reversals in flow direction occurred rapidly (less than 1 hour), and complete reversals (resulting in near peak net-upstream or downstream discharges) occurred within a few hours of slack water. Observations of simultaneous upstream and downstream flow (bidirectional flow) were quite common in the ADCP measurements, with opposing directions of flow occurring predominantly in vertical layers. Continuous (every 15 minutes) discharge data were computed for the period from August 18, 1995, to September 28, 1995, and filtered daily mean discharge values were computed for the period from August 19 to September 26, 1995. Data were not computed prior to August 18, 1995, either because of missing data or because the velocity rating was poorly defined (because of insufficient data) for the period prior to landfall of hurricane Erin (August 3, 1995). The results of the study indicate that acoustical techniques can yield useful estimates of continuous (instantaneous) discharge in Perdido Bay. Useful estimates of average daily net flow rates can also be obtained, but the accuracy of these estimates will be limited by small rating shifts that introduce bias into the instantaneous values that are used to compute the net flows. Instantaneous loads of total nitrogen ranged from -180 to 220 grams per second for the samples collected during the study, and instantaneous loads of total phosphorous ranged from -10 to 11 grams per second (negative loads indicate net upstream transport). The chloride concentrations from the water samples collected from Perdido Bay indicated a significant amount of mixing of saltwater and freshwater. Mixing effects could greatly reduce the accuracy of estimates of net loads of nutrients or other substances. The study results indicate that acoustical techniques can yield acceptable estimates of instantaneous loads in Perdido Bay. However, estimates of net loads should be interpreted with great caution and may have unacceptably large errors, especially when saltwater and freshwater concentrations differ greatly.

  2. Genetic connectivity for two bear species at wildlife crossing structures in Banff National Park.

    PubMed

    Sawaya, Michael A; Kalinowski, Steven T; Clevenger, Anthony P

    2014-04-07

    Roads can fragment and isolate wildlife populations, which will eventually decrease genetic diversity within populations. Wildlife crossing structures may counteract these impacts, but most crossings are relatively new, and there is little evidence that they facilitate gene flow. We conducted a three-year research project in Banff National Park, Alberta, to evaluate the effectiveness of wildlife crossings to provide genetic connectivity. Our main objective was to determine how the Trans-Canada Highway and crossing structures along it affect gene flow in grizzly (Ursus arctos) and black bears (Ursus americanus). We compared genetic data generated from wildlife crossings with data collected from greater bear populations. We detected a genetic discontinuity at the highway in grizzly bears but not in black bears. We assigned grizzly bears that used crossings to populations north and south of the highway, providing evidence of bidirectional gene flow and genetic admixture. Parentage tests showed that 47% of black bears and 27% of grizzly bears that used crossings successfully bred, including multiple males and females of both species. Differentiating between dispersal and gene flow is difficult, but we documented gene flow by showing migration, reproduction and genetic admixture. We conclude that wildlife crossings allow sufficient gene flow to prevent genetic isolation.

  3. Genetic connectivity for two bear species at wildlife crossing structures in Banff National Park

    PubMed Central

    Sawaya, Michael A.; Kalinowski, Steven T.; Clevenger, Anthony P.

    2014-01-01

    Roads can fragment and isolate wildlife populations, which will eventually decrease genetic diversity within populations. Wildlife crossing structures may counteract these impacts, but most crossings are relatively new, and there is little evidence that they facilitate gene flow. We conducted a three-year research project in Banff National Park, Alberta, to evaluate the effectiveness of wildlife crossings to provide genetic connectivity. Our main objective was to determine how the Trans-Canada Highway and crossing structures along it affect gene flow in grizzly (Ursus arctos) and black bears (Ursus americanus). We compared genetic data generated from wildlife crossings with data collected from greater bear populations. We detected a genetic discontinuity at the highway in grizzly bears but not in black bears. We assigned grizzly bears that used crossings to populations north and south of the highway, providing evidence of bidirectional gene flow and genetic admixture. Parentage tests showed that 47% of black bears and 27% of grizzly bears that used crossings successfully bred, including multiple males and females of both species. Differentiating between dispersal and gene flow is difficult, but we documented gene flow by showing migration, reproduction and genetic admixture. We conclude that wildlife crossings allow sufficient gene flow to prevent genetic isolation. PMID:24552834

  4. Calculation of the diameter of the central retinal artery from noninvasive measurements in humans.

    PubMed

    Dorner, Guido T; Polska, Elzbieta; Garhöfer, Gerhard; Zawinka, Claudia; Frank, Barbara; Schmetterer, Leopold

    2002-12-01

    The aim of the present study was to calculate the diameter of the central retinal artery from results as obtained with non-invasive techniques in healthy young subjects. Twenty-four healthy male subjects participated in this study. Total retinal blood flow was calculated from combined bi-directional laser Doppler velocimetry and measurement of retinal venous diameters using the Zeiss retinal vessel analyzer. Using these techniques red blood cell velocity and vessel diameters of all visible veins entering the optic nerve head were measured and total retinal blood flow was calculated. Blood flow velocity in the central retinal artery was measured with color Doppler imaging. Form these outcome parameters the diameter of the central retinal artery was calculated for each subject individually. In the present study cohort the mean retinal blood flow was 38.1 +/- 9.1 microl/min and the mean flow velocity in the central retinal artery was 6.3 +/- 1.2 cm/s. From these data we calculated a mean diameter of the central retinal artery of 163 +/- 17 microm. Our results are in good agreement with data obtained from in vitro studies. The data of the present study also indicate that one needs to be careful to interpret velocity data from the central retinal artery in terms of retinal blood flow.

  5. Protein Solvent-Accessibility Prediction by a Stacked Deep Bidirectional Recurrent Neural Network.

    PubMed

    Zhang, Buzhong; Li, Linqing; Lü, Qiang

    2018-05-25

    Residue solvent accessibility is closely related to the spatial arrangement and packing of residues. Predicting the solvent accessibility of a protein is an important step to understand its structure and function. In this work, we present a deep learning method to predict residue solvent accessibility, which is based on a stacked deep bidirectional recurrent neural network applied to sequence profiles. To capture more long-range sequence information, a merging operator was proposed when bidirectional information from hidden nodes was merged for outputs. Three types of merging operators were used in our improved model, with a long short-term memory network performing as a hidden computing node. The trained database was constructed from 7361 proteins extracted from the PISCES server using a cut-off of 25% sequence identity. Sequence-derived features including position-specific scoring matrix, physical properties, physicochemical characteristics, conservation score and protein coding were used to represent a residue. Using this method, predictive values of continuous relative solvent-accessible area were obtained, and then, these values were transformed into binary states with predefined thresholds. Our experimental results showed that our deep learning method improved prediction quality relative to current methods, with mean absolute error and Pearson's correlation coefficient values of 8.8% and 74.8%, respectively, on the CB502 dataset and 8.2% and 78%, respectively, on the Manesh215 dataset.

  6. Bidirectional fiber-wireless and fiber-VLLC transmission system based on an OEO-based BLS and a RSOA.

    PubMed

    Lu, Hai-Han; Li, Chung-Yi; Lu, Ting-Chien; Wu, Chang-Jen; Chu, Chien-An; Shiva, Ajay; Mochii, Takao

    2016-02-01

    A bidirectional fiber-wireless and fiber-visible-laser-light-communication (VLLC) transmission system based on an optoelectronic oscillator (OEO)-based broadband light source (BLS) and a reflective semiconductor optical amplifier (RSOA) is proposed and experimentally demonstrated. Through an in-depth observation of such bidirectional fiber-wireless and fiber-VLLC transmission systems, good bit error rate performances are obtained over a 40 km single-mode fiber and a 10 m RF/optical wireless transport. Such a bidirectional fiber-wireless and fiber-VLLC transmission system is an attractive option for providing broadband integrated services.

  7. Multichannel signal enhancement

    DOEpatents

    Lewis, Paul S.

    1990-01-01

    A mixed adaptive filter is formulated for the signal processing problem where desired a priori signal information is not available. The formulation generates a least squares problem which enables the filter output to be calculated directly from an input data matrix. In one embodiment, a folded processor array enables bidirectional data flow to solve the recursive problem by back substitution without global communications. In another embodiment, a balanced processor array solves the recursive problem by forward elimination through the array. In a particular application to magnetoencephalography, the mixed adaptive filter enables an evoked response to an auditory stimulus to be identified from only a single trial.

  8. Lamination cooling system formation method

    DOEpatents

    Rippel, Wally E [Altadena, CA; Kobayashi, Daryl M [Monrovia, CA

    2012-06-19

    An electric motor, transformer or inductor having a cooling system. A stack of laminations have apertures at least partially coincident with apertures of adjacent laminations. The apertures define straight or angled cooling-fluid passageways through the lamination stack. Gaps between the adjacent laminations are sealed by injecting a heat-cured sealant into the passageways, expelling excess sealant, and heat-curing the lamination stack. Manifold members adjoin opposite ends of the lamination stack, and each is configured with one or more cavities to act as a manifold to adjacent passageway ends. Complex manifold arrangements can create bidirectional flow in a variety of patterns.

  9. Lamination cooling system formation method

    DOEpatents

    Rippel, Wally E [Altadena, CA; Kobayashi, Daryl M [Monrovia, CA

    2009-05-12

    An electric motor, transformer or inductor having a cooling system. A stack of laminations have apertures at least partially coincident with apertures of adjacent laminations. The apertures define straight or angled cooling-fluid passageways through the lamination stack. Gaps between the adjacent laminations are sealed by injecting a heat-cured sealant into the passageways, expelling excess sealant, and heat-curing the lamination stack. Manifold members adjoin opposite ends of the lamination stack, and each is configured with one or more cavities to act as a manifold to adjacent passageway ends. Complex manifold arrangements can create bidirectional flow in a variety of patterns.

  10. Particle and field characteristics of the high-latitude plasma sheet boundary layer

    NASA Technical Reports Server (NTRS)

    Parks, G. K.; Mccarthy, M.; Fitzenreiter, R. J.; Ogilvie, K. W.; Etcheto, J.; Anderson, K. A.; Lin, R. P.; Anderson, R. R.; Eastman, T. E.; Frank, L. A.

    1984-01-01

    Particle and field data obtained by eight ISEE spacecraft experiments are used to define more precisely the characteristics of the high-latitude boundary region of the plasma sheet. A region immediately adjacent to the high-latitude plasma sheet boundary has particle and field characteristics distinctly different from those observed in the lobe and deeper in the central plasma sheet. Electrons over a broad energy interval are 'field-aligned' and bidirectional, whereas in the plasma sheet the distributions are more isotropic. The region supports intense ion flows, large-amplitude electric fields, and enhanced broad-band electrostatic noise.

  11. Annual Research Review: Embracing Not Erasing Contextual Variability in Children's Behavior--Theory and Utility in the Selection and Use of Methods and Informants in Developmental Psychopathology

    ERIC Educational Resources Information Center

    Dirks, Melanie A.; De Los Reyes, Andres; Briggs-Gowan, Margaret; Cella, David; Wakschlag, Lauren S.

    2012-01-01

    This paper examines the selection and use of multiple methods and informants for the assessment of disruptive behavior syndromes and attention deficit/hyperactivity disorder, providing a critical discussion of (a) the bidirectional linkages between theoretical models of childhood psychopathology and current assessment techniques; and (b) current…

  12. Surface roughness effects on bidirectional reflectance

    NASA Technical Reports Server (NTRS)

    Smith, T. F.; Hering, R. G.

    1972-01-01

    An experimental study of surface roughness effects on bidirectional reflectance of metallic surfaces is presented. A facility capable of irradiating a sample from normal to grazing incidence and recording plane of incidence bidirectional reflectance measurements was developed. Samples consisting of glass, aluminum alloy, and stainless steel materials were selected for examination. Samples were roughened using standard grinding techniques and coated with a radiatively opaque layer of pure aluminum. Mechanical surface roughness parameters, rms heights and rms slopes, evaluated from digitized surface profile measurements are less than 1.0 micrometers and 0.28, respectively. Rough surface specular, bidirectional, and directional reflectance measurements for selected values of polar angle of incidence and wavelength of incident energy within the spectral range of 1 to 14 micrometers are reported. The Beckmann bidirectional reflectance model is compared with reflectance measurements to establish its usefulness in describing the magnitude and spatial distribution of energy reflected from rough surfaces.

  13. Nonlinear reconnecting edge localized modes in current-carrying plasmas

    DOE PAGES

    Ebrahimi, F.

    2017-05-22

    Nonlinear edge localized modes in a tokamak are examined using global three-dimensional resistive magnetohydrodynamics simulations. Coherent current-carrying filament (ribbon-like) structures wrapped around the torus are nonlinearly formed due to nonaxisymmetric reconnecting current sheet instabilities, the so-called peeling-like edge localized modes. These fast growing modes saturate by breaking axisymmetric current layers isolated near the plasma edge and go through repetitive relaxation cycles by expelling current radially outward and relaxing it back. The local bidirectional fluctuation-induced electromotive force (emf) from the edge localized modes, the dynamo action, relaxes the axisymmetric current density and forms current holes near the edge. Furthermore, the three-dimensionalmore » coherent current-carrying filament structures (sometimes referred to as 3-D plasmoids) observed here should also have strong implications for solar and astrophysical reconnection.« less

  14. Depositional architecture and evolution of the Late Miocene slope channel-fan-system in the northeastern shelf-margin of South China Sea

    NASA Astrophysics Data System (ADS)

    Jiang, Jing; Lin, Changsong; Zhang, Zhongtao; Tian, Hongxun; Tao, Ze; Liu, Hanyao

    2016-04-01

    The Upper Miocene in the Pearl River Mouth Basin of northwestern shelf-margin of South China Sea Basin contains a series of slope channel - fan systems. Their depositional architecture and evolution are documented in this investigation based on an integrated analysis of cores, logs, and seismic data. Four depositional-palaeogeomorphological elements have been identified in the slope channel-fan systems as follows: broad, shallow and unconfined or partly confined outer-shelf to shelf-break channels; deeply incised and confined unidirectionally migrating slope channels; broad or U-shaped, unconfined erosional-depositional channels; frontal splays-lobes and nonchannelized sheets. The slope channels are mostly oriented NW-SE, which migrated unidirectionally northeastwards and intensively eroded almost the whole shelf-slope zone. The channel infillings are mainly mudstones, interbedded with siltstones. They might be formed by gravity flow erosion as bypassing channels. They were filled with limited gravity flow sediments at the base and mostly filled with lateral accretionary packages of bottom current deposits. At the end of the channels, a series of small-scale slope fans developed and coalesced into fan aprons along the base of the slope. The unconfined erosional-depositional channels at the upper parts of the fan-apron-systems display compound infill patterns, and commonly have concave erosional bases and convex tops. The frontal splays-lobes representing middle to distal deposits of fan-apron-systems have flat-mounded or gull-wing geometries, and the internal architectures include bidirectional downlap, progradation, and chaotic infillings. The distal nonchannelized turbidite sheets are characterized by thin-bedded, parallel to sub-parallel sheet-like geometries. Three major unconformities or obvious erosional surfaces in the channel-fan systems of the Upper Miocene are recognized, and indicate the falling of sea-level. The depositional architecture of sequences varies from the upper slope to the slope base transitional to basin plain. The basal erosion and the unidirectionally migrating characters of the slope channels were supposed to be the result of the interaction of bottom currents and gravity flows. The intensive development of the channel-fan systems over the shelf slope might be related to the Dongsha Tectonic uplift which may resulted in stepped slope and concomitantly intensified gravity flow in the study area in Late Miocene.

  15. Structure and Function of the Bi-Directional Bacterial Flagellar Motor

    PubMed Central

    Morimoto, Yusuke V.; Minamino, Tohru

    2014-01-01

    The bacterial flagellum is a locomotive organelle that propels the bacterial cell body in liquid environments. The flagellum is a supramolecular complex composed of about 30 different proteins and consists of at least three parts: a rotary motor, a universal joint, and a helical filament. The flagellar motor of Escherichia coli and Salmonella enterica is powered by an inward-directed electrochemical potential difference of protons across the cytoplasmic membrane. The flagellar motor consists of a rotor made of FliF, FliG, FliM and FliN and a dozen stators consisting of MotA and MotB. FliG, FliM and FliN also act as a molecular switch, enabling the motor to spin in both counterclockwise and clockwise directions. Each stator is anchored to the peptidoglycan layer through the C-terminal periplasmic domain of MotB and acts as a proton channel to couple the proton flow through the channel with torque generation. Highly conserved charged residues at the rotor–stator interface are required not only for torque generation but also for stator assembly around the rotor. In this review, we will summarize our current understanding of the structure and function of the proton-driven bacterial flagellar motor. PMID:24970213

  16. Structure and function of the bi-directional bacterial flagellar motor.

    PubMed

    Morimoto, Yusuke V; Minamino, Tohru

    2014-02-18

    The bacterial flagellum is a locomotive organelle that propels the bacterial cell body in liquid environments. The flagellum is a supramolecular complex composed of about 30 different proteins and consists of at least three parts: a rotary motor, a universal joint, and a helical filament. The flagellar motor of Escherichia coli and Salmonella enterica is powered by an inward-directed electrochemical potential difference of protons across the cytoplasmic membrane. The flagellar motor consists of a rotor made of FliF, FliG, FliM and FliN and a dozen stators consisting of MotA and MotB. FliG, FliM and FliN also act as a molecular switch, enabling the motor to spin in both counterclockwise and clockwise directions. Each stator is anchored to the peptidoglycan layer through the C-terminal periplasmic domain of MotB and acts as a proton channel to couple the proton flow through the channel with torque generation. Highly conserved charged residues at the rotor-stator interface are required not only for torque generation but also for stator assembly around the rotor. In this review, we will summarize our current understanding of the structure and function of the proton-driven bacterial flagellar motor.

  17. Review of droop-controlled bi-directional inverter in conducting islanded operation of photovoltaic systems

    NASA Astrophysics Data System (ADS)

    Khaw, Ace Lin Yi; Wong, Jianhui; Lim, Yun Seng

    2017-04-01

    Global warming due to the excessive greenhouse gas emissions has led to the emergence of green technologies in Malaysia, particularly photovoltaic (PV) systems. Under the current regulatory framework, islanded operation of the PV system is not permissible. As a result, any renewable energy sources will be disconnected immediately in the event of grid outages. This practice is to ensure the safety of working personnel, as well as the customer equipment connected within the distribution networks. In addition, there is no synchronizing equipment to aid the reconnection of the islanded network to the grid. However, with the shutdown of the Distributed Generator (DG) during islanded operation, the customers are not able to utilize the available renewable energy and the number of power interruption is not improved with the renewable energy sources. Therefore, the main objective of this paper is to investigate the feasibility of the PV system in conducting islanding operation with the use of Energy Storage System (ESS). This paper also proposes a control algorithm to maintain the voltage and frequency excursion within the statutory limit by manipulating the real and reactive power flow of the ESS within the transition period between grid connected and islanding operation.

  18. CUSP-SHAPED STRUCTURE OF A JET OBSERVED BY IRIS AND SDO

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Yuzong; Zhang, Jun, E-mail: yuzong@nao.cas.cn, E-mail: zjun@nao.cas.cn

    2017-01-01

    On 2014 August 29, the trigger and evolution of a cusp-shaped jet were captured in detail at 1330 Å by the Interface Region Imaging Spectrograph . At first, two neighboring mini-prominences arose in turn from the low solar atmosphere and collided with a loop-like system over them. The collisions between the loop-like system and the mini-prominences lead to the blowout, and then a cusp-shaped jet formed with a spire and an arch-base. In the spire, many brightening blobs originating from the junction between the spire and the arch-base moved upward in a rotating manner and then in a straight line inmore » the late phase of the jet. In the arch-base, dark and bright material simultaneously tracked in a fan-like structure, and the majority of the material moved along the fan's threads. At the later phase of the jet's evolution, bidirectional flows emptied the arch-base, while downflows emptied the spire, thus making the jet entirely vanish. The extremely detailed observations in this study shed new light on how magnetic reconnection alters the inner topological structure of a jet and provides a beneficial complement for understanding current jet models.« less

  19. Framewise phoneme classification with bidirectional LSTM and other neural network architectures.

    PubMed

    Graves, Alex; Schmidhuber, Jürgen

    2005-01-01

    In this paper, we present bidirectional Long Short Term Memory (LSTM) networks, and a modified, full gradient version of the LSTM learning algorithm. We evaluate Bidirectional LSTM (BLSTM) and several other network architectures on the benchmark task of framewise phoneme classification, using the TIMIT database. Our main findings are that bidirectional networks outperform unidirectional ones, and Long Short Term Memory (LSTM) is much faster and also more accurate than both standard Recurrent Neural Nets (RNNs) and time-windowed Multilayer Perceptrons (MLPs). Our results support the view that contextual information is crucial to speech processing, and suggest that BLSTM is an effective architecture with which to exploit it.

  20. Estimation of shortwave hemispherical reflectance (albedo) from bidirectionally reflected radiance data

    NASA Technical Reports Server (NTRS)

    Starks, Patrick J.; Norman, John M.; Blad, Blaine L.; Walter-Shea, Elizabeth A.; Walthall, Charles L.

    1991-01-01

    An equation for estimating albedo from bidirectional reflectance data is proposed. The estimates of albedo are found to be greater than values obtained with simultaneous pyranometer measurements. Particular attention is given to potential sources of systematic errors including extrapolation of bidirectional reflectance data out to a view zenith angle of 90 deg, the use of inappropriate weighting coefficients in the numerator of the albedo equation, surface shadowing caused by the A-frame instrumentation used to measure the incoming and outgoing radiation fluxes, errors in estimates of the denominator of the proposed albedo equation, and a 'hot spot' contribution in bidirectional data measured by a modular multiband radiometer.

  1. Design of PI Controlled Non Isolated Bidirectional DC to DC Converter for Electric Vehicle Application

    NASA Astrophysics Data System (ADS)

    Geetha, A.; Subramani, C.; Thamizh Thentral, T. M.; Krithika, V.; Usha, S.

    2018-04-01

    Non isolated Bidirectional DC-DC Converter (NIBDDC) is a good interface between DC source and inverter Fed induction motor drive. This paper deals with comparison between open loop and PI controlled Bidirectional DC to DC Converter Inverter System (BDDCIS). The modelling and control of BDDC is becomes an important issue. Open loop BDDCIS and closed loop PI controlled BDDCIS are designed, modelled and simulated using Matlab- simulink and their results are presented. The investigations indicate superior performance of PI controlled BDDCIS. The proposed BDDCIS has advantages like bidirectional power transfer ability, reduced hardware count and improved dynamic response.

  2. Modeling Sustainability: Population, Inequality, Consumption, and Bidirectional Coupling of the Earth and Human Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Motesharrei, Safa; Rivas, Jorge; Kalnay, Eugenia

    Over the last two centuries, the impact of the Human System has grown dramatically, becoming strongly dominant within the Earth System in many different ways. Consumption, inequality, and population have increased extremely fast, especially since about 1950, threatening to overwhelm the many critical functions and ecosystems of the Earth System. Changes in the Earth System, in turn, have important feedback effects on the Human System, with costly and potentially serious consequences. However, current models do not incorporate these critical feedbacks. Here, we argue that in order to understand the dynamics of either system, Earth System Models must be coupled withmore » Human System Models through bidirectional couplings representing the positive, negative, and delayed feedbacks that exist in the real systems. In particular, key Human System variables, such as demographics, inequality, economic growth, and migration, are not coupled with the Earth System but are instead driven by exogenous estimates, such as United Nations population projections.This makes current models likely to miss important feedbacks in the real Earth–Human system, especially those that may result in unexpected or counterintuitive outcomes, and thus requiring different policy interventions from current models. Lastly, the importance and imminence of sustainability challenges, the dominant role of the Human System in the Earth System, and the essential roles the Earth System plays for the Human System, all call for collaboration of natural scientists, social scientists, and engineers in multidisciplinary research and modeling to develop coupled Earth–Human system models for devising effective science-based policies and measures to benefit current and future generations.« less

  3. Modeling Sustainability: Population, Inequality, Consumption, and Bidirectional Coupling of the Earth and Human Systems

    NASA Technical Reports Server (NTRS)

    Motesharrei, Safa; Rivas, Jorge; Kalnay, Eugenia; Asrar, Ghassem R.; Busalacchi, Antonio J.; Cahalan, Robert F.; Cane, Mark A.; Colwell, Rita R.; Feng, Kuishuang; Franklin, Rachel S.; hide

    2016-01-01

    Over the last two centuries, the impact of the Human System has grown dramatically, becoming strongly dominant within the Earth System in many different ways. Consumption, inequality, and population have increased extremely fast, especially since about 1950, threatening to overwhelm the many critical functions and ecosystems of the Earth System. Changes in the Earth System, in turn, have important feedback effects on the Human System, with costly and potentially serious consequences. However, current models do not incorporate these critical feedbacks. We argue that in order to understand the dynamics of either system, Earth System Models must be coupled with Human System Models through bidirectional couplings representing the positive, negative, and delayed feedbacks that exist in the real systems. In particular, key Human System variables, such as demographics, inequality, economic growth, and migration, are not coupled with the Earth System but are instead driven by exogenous estimates, such as UN population projections. This makes current models likely to miss important feedbacks in the real Earth-Human system, especially those that may result in unexpected or counterintuitive outcomes, and thus requiring different policy interventions from current models. The importance and imminence of sustainability challenges, the dominant role of the Human System in the Earth System, and the essential roles the Earth System plays for the Human System, all call for collaboration of natural scientists, social scientists, and engineers in multidisciplinary research and modeling to develop coupled Earth-Human system models for devising effective science-based policies and measures to benefit current and future generations.

  4. Modeling Sustainability: Population, Inequality, Consumption, and Bidirectional Coupling of the Earth and Human Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Motesharrei, Safa; Rivas, Jorge; Kalnay, Eugenia

    Over the last two centuries, the impact of the Human System has grown dramatically, becoming strongly dominant within the Earth System in many different ways. Consumption, inequality, and population have increased extremely fast, especially since about 1950, threatening to overwhelm the many critical functions and ecosystems of the Earth System. Changes in the Earth System, in turn, have important feedback effects on the Human System, with costly and potentially serious consequences. However, current models do not incorporate these critical feedbacks. We argue that in order to understand the dynamics of either system, Earth System Models must be coupled with Humanmore » System Models through bidirectional couplings representing the positive, negative, and delayed feedbacks that exist in the real systems. In particular, key Human System variables, such as demographics, inequality, economic growth, and migration, are not coupled with the Earth System but are instead driven by exogenous estimates, such as United Nations population projections. This makes current models likely to miss important feedbacks in the real Earth–Human system, especially those that may result in unexpected or counterintuitive outcomes, and thus requiring different policy interventions from current models. The importance and imminence of sustainability challenges, the dominant role of the Human System in the Earth System, and the essential roles the Earth System plays for the Human System, all call for collaboration of natural scientists, social scientists, and engineers in multidisciplinary research and modeling to develop coupled Earth–Human system models for devising effective science-based policies and measures to benefit current and future generations.« less

  5. Modeling Sustainability: Population, Inequality, Consumption, and Bidirectional Coupling of the Earth and Human Systems

    DOE PAGES

    Motesharrei, Safa; Rivas, Jorge; Kalnay, Eugenia; ...

    2016-12-11

    Over the last two centuries, the impact of the Human System has grown dramatically, becoming strongly dominant within the Earth System in many different ways. Consumption, inequality, and population have increased extremely fast, especially since about 1950, threatening to overwhelm the many critical functions and ecosystems of the Earth System. Changes in the Earth System, in turn, have important feedback effects on the Human System, with costly and potentially serious consequences. However, current models do not incorporate these critical feedbacks. Here, we argue that in order to understand the dynamics of either system, Earth System Models must be coupled withmore » Human System Models through bidirectional couplings representing the positive, negative, and delayed feedbacks that exist in the real systems. In particular, key Human System variables, such as demographics, inequality, economic growth, and migration, are not coupled with the Earth System but are instead driven by exogenous estimates, such as United Nations population projections.This makes current models likely to miss important feedbacks in the real Earth–Human system, especially those that may result in unexpected or counterintuitive outcomes, and thus requiring different policy interventions from current models. Lastly, the importance and imminence of sustainability challenges, the dominant role of the Human System in the Earth System, and the essential roles the Earth System plays for the Human System, all call for collaboration of natural scientists, social scientists, and engineers in multidisciplinary research and modeling to develop coupled Earth–Human system models for devising effective science-based policies and measures to benefit current and future generations.« less

  6. Moving domain computational fluid dynamics to interface with an embryonic model of cardiac morphogenesis.

    PubMed

    Lee, Juhyun; Moghadam, Mahdi Esmaily; Kung, Ethan; Cao, Hung; Beebe, Tyler; Miller, Yury; Roman, Beth L; Lien, Ching-Ling; Chi, Neil C; Marsden, Alison L; Hsiai, Tzung K

    2013-01-01

    Peristaltic contraction of the embryonic heart tube produces time- and spatial-varying wall shear stress (WSS) and pressure gradients (∇P) across the atrioventricular (AV) canal. Zebrafish (Danio rerio) are a genetically tractable system to investigate cardiac morphogenesis. The use of Tg(fli1a:EGFP) (y1) transgenic embryos allowed for delineation and two-dimensional reconstruction of the endocardium. This time-varying wall motion was then prescribed in a two-dimensional moving domain computational fluid dynamics (CFD) model, providing new insights into spatial and temporal variations in WSS and ∇P during cardiac development. The CFD simulations were validated with particle image velocimetry (PIV) across the atrioventricular (AV) canal, revealing an increase in both velocities and heart rates, but a decrease in the duration of atrial systole from early to later stages. At 20-30 hours post fertilization (hpf), simulation results revealed bidirectional WSS across the AV canal in the heart tube in response to peristaltic motion of the wall. At 40-50 hpf, the tube structure undergoes cardiac looping, accompanied by a nearly 3-fold increase in WSS magnitude. At 110-120 hpf, distinct AV valve, atrium, ventricle, and bulbus arteriosus form, accompanied by incremental increases in both WSS magnitude and ∇P, but a decrease in bi-directional flow. Laminar flow develops across the AV canal at 20-30 hpf, and persists at 110-120 hpf. Reynolds numbers at the AV canal increase from 0.07±0.03 at 20-30 hpf to 0.23±0.07 at 110-120 hpf (p< 0.05, n=6), whereas Womersley numbers remain relatively unchanged from 0.11 to 0.13. Our moving domain simulations highlights hemodynamic changes in relation to cardiac morphogenesis; thereby, providing a 2-D quantitative approach to complement imaging analysis.

  7. Arrhythmogenic Mechanisms in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

    PubMed Central

    Cerrone, Marina; Noujaim, Sami F.; Tolkacheva, Elena G.; Talkachou, Arkadzi; O’Connell, Ryan; Berenfeld, Omer; Anumonwo, Justus; Pandit, Sandeep V.; Vikstrom, Karen; Napolitano, Carlo; Priori, Silvia G.; Jalife, José

    2008-01-01

    Catecholaminergic polymorphic ventricular tachycardia (VT) is a lethal familial disease characterized by bidirectional VT, polymorphic VT, and ventricular fibrillation. Catecholaminergic polymorphic VT is caused by enhanced Ca2+ release through defective ryanodine receptor (RyR2) channels. We used epicardial and endocardial optical mapping, chemical subendocardial ablation with Lugol’s solution, and patch clamping in a knockin (RyR2/RyR2R4496C) mouse model to investigate the arrhythmogenic mechanisms in catecholaminergic polymorphic VT. In isolated hearts, spontaneous ventricular arrhythmias occurred in 54% of 13 RyR2/RyR2R4496C and in 9% of 11 wild-type (P=0.03) littermates perfused with Ca2+ and isoproterenol; 66% of 12 RyR2/RyR2R4496C and 20% of 10 wild-type hearts perfused with caffeine and epinephrine showed arrhythmias (P=0.04). Epicardial mapping showed that monomorphic VT, bidirectional VT, and polymorphic VT manifested as concentric epicardial breakthrough patterns, suggesting a focal origin in the His–Purkinje networks of either or both ventricles. Monomorphic VT was clearly unifocal, whereas bidirectional VT was bifocal. Polymorphic VT was initially multifocal but eventually became reentrant and degenerated into ventricular fibrillation. Endocardial mapping confirmed the Purkinje fiber origin of the focal arrhythmias. Chemical ablation of the right ventricular endocardial cavity with Lugol’s solution induced complete right bundle branch block and converted the bidirectional VT into monomorphic VT in 4 anesthetized RyR2/RyR2R4496C mice. Under current clamp, single Purkinje cells from RyR2/RyR2R4496C mouse hearts generated delayed afterdepolarization–induced triggered activity at lower frequencies and level of adrenergic stimulation than wild-type. Overall, the data demonstrate that the His–Purkinje system is an important source of focal arrhythmias in catecholaminergic polymorphic VT. PMID:17872467

  8. Bidirectional Associations between Parenting Practices and Conduct Problems in Boys from Childhood to Adolescence: The Moderating Effect of Age and African-American Ethnicity

    ERIC Educational Resources Information Center

    Pardini, Dustin A.; Fite, Paula J.; Burke, Jeffrey D.

    2008-01-01

    This study examined the bidirectional relationship between parent and teacher reported conduct problems in youth and parenting practices using a longitudinal sample of boys assessed from 6 to 16 years of age. Analyses tested whether these bidirectional associations changed across development and whether the nature of these associations varied…

  9. Bidirectional DC-DC conversion device use at system of urban electric transport

    NASA Astrophysics Data System (ADS)

    Vilberger, M. E.; Vislogusov, D. P.; Kotin, D. A.; Kulekina, A. V.

    2017-10-01

    The paper considers questions of energy storage devices used in electric transport, especially in the electric traction drive of a trolley bus, in order to provide an autonomous motion, overhead system’s load leveling and energy recovering. For efficiency of the proposed system, a bidirectional DC-DC converter is used. During the simulation, regulation characteristics of the bidirectional DC-DC converters were obtained.

  10. Oxygen-assisted multipass cutting of carbon fiber reinforced plastics with ultra-short laser pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kononenko, T. V.; Komlenok, M. S.; Konov, V. I.

    Deep multipass cutting of bidirectional and unidirectional carbon fiber reinforced plastics (CFRP) with picosecond laser pulses was investigated in different static atmospheres as well as with the assistance of an oxygen or nitrogen gas flow. The ablation rate was determined as a function of the kerf depth and the resulting heat affected zone was measured. An assisting oxygen gas flow is found to significantly increase the cutting productivity, but only in deep kerfs where the diminished evaporative ablation due to the reduced laser fluence reaching the bottom of the kerf does not dominate the contribution of reactive etching anymore. Oxygen-supportedmore » cutting was shown to also solve the problem that occurs when cutting the CFRP parallel to the fiber orientation where a strong deformation and widening of the kerf, which temporarily slows down the process speed, is revealed to be typical for processing in standard air atmospheres.« less

  11. Plasma regimes in the deep geomagnetic tail - ISEE 3

    NASA Astrophysics Data System (ADS)

    Bame, S. J.; Anderson, R. C.; Asbridge, J. R.; Baker, D. N.; Feldman, W. C.; Gosling, J. T.; Hones, E. W., Jr.; McComas, D. J.; Zwickl, R. D.

    1983-09-01

    The spacecraft remained close to or within a previously unexplored part of the distant (60-220 earth radii) geomagnetic tail nearly continuously from January 1 to March 30, 1983. Analysis of the data reveals that all of the plasma regimes identified previously with near-earth measurements (plasma sheet, low-latitude boundary layer, plasma mantle, lobe, and magnetosheath) remain recognizable in the distant tail. These regimes, however, are found to be intermingled in a more chaotic fashion than near the earth. Within the plasma sheet at approximately 200 earth radii, typical flow velocities are about 500 km/s tailward, considerably higher than in the near-earth plasma sheet. Earthward flow within the plasma sheet is observed occasionally, indicating the temporary presence of a neutral line beyond 220 earth radii. Also found are strong bidirectional electron anisotropies throughout much of the distant plasma sheet, boundary layer, and magnetosheath.

  12. Non-Cooperative Facial Recognition Video Dataset Collection Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kimura, Marcia L.; Erikson, Rebecca L.; Lombardo, Nicholas J.

    The Pacific Northwest National Laboratory (PNNL) will produce a non-cooperative (i.e. not posing for the camera) facial recognition video data set for research purposes to evaluate and enhance facial recognition systems technology. The aggregate data set consists of 1) videos capturing PNNL role players and public volunteers in three key operational settings, 2) photographs of the role players for enrolling in an evaluation database, and 3) ground truth data that documents when the role player is within various camera fields of view. PNNL will deliver the aggregate data set to DHS who may then choose to make it available tomore » other government agencies interested in evaluating and enhancing facial recognition systems. The three operational settings that will be the focus of the video collection effort include: 1) unidirectional crowd flow 2) bi-directional crowd flow, and 3) linear and/or serpentine queues.« less

  13. Bidirectional Associations between Peer Victimization and Functions of Aggression in Middle Childhood: Further Evaluation across Informants and Academic Years.

    PubMed

    Cooley, John L; Fite, Paula J; Pederson, Casey A

    2018-01-01

    The current 3-wave study examined bidirectional associations between peer victimization and functions of aggression across informants over a 1-year period in middle childhood, with attention to potential gender differences. Participants included 198 children (51% girls) in the third and fourth grades and their homeroom teachers. Peer victimization was assessed using both child- and teacher-reports, and teachers provided ratings of reactive and proactive aggression. Cross-classified multilevel cross-lagged models indicated that child-reports, but not teacher-reports, of peer victimization predicted higher levels of reactive aggression within and across academic years. Further, reactive aggression predicted subsequent increases in child- and teacher-reports of peer victimization across each wave of data. Several gender differences, particularly in the crossed paths between proactive aggression and peer victimization, also emerged. Whereas peer victimization was found to partially account for the stability of reactive aggression over time, reactive aggression did not account for the stability of peer victimization. Taken together with previous research, the current findings suggest that child-reports of peer victimization may help identify youth who are risk for exhibiting increased reactive aggression over time. Further, they highlight the need to target reactively aggressive behavior for the prevention of peer victimization in middle childhood.

  14. Fully nonlinear theory of transcritical shallow-water flow past topography

    NASA Astrophysics Data System (ADS)

    El, Gennady; Grimshaw, Roger; Smyth, Noel

    2010-05-01

    In this talk recent results on the generation of undular bores in one-dimensional fully nonlinear shallow-water flows past localised topographies will be presented. The description is made in the framework of the forced Su-Gardner (a.k.a. 1D Green-Naghdi) system of equations, with a primary focus on the transcritical regime when the Froude number of the oncoming flow is close to unity. A combination of the local transcritical hydraulic solution over the localized topography, which produces upstream and downstream hydraulic jumps, and unsteady undular bore solutions describing the resolution of these hydraulic jumps, is used to describe various flow regimes depending on the combination of the topography height and the Froude number. We take advantage of the recently developed modulation theory of Su-Gardner undular bores to derive the main parameters of transcritical fully nonlinear shallow-water flow, such as the leading solitary wave amplitudes for the upstream and downstream undular bores, the speeds of the undular bores edges and the drag force. Our results confirm that most of the features of the previously developed description in the framework of the uni-directional forced KdV model hold up qualitatively for finite amplitude waves, while the quantitative description can be obtained in the framework of the bi-directional forced Su-Gardner system.

  15. Plane-wave transverse oscillation for high-frame-rate 2-D vector flow imaging.

    PubMed

    Lenge, Matteo; Ramalli, Alessandro; Tortoli, Piero; Cachard, Christian; Liebgott, Hervé

    2015-12-01

    Transverse oscillation (TO) methods introduce oscillations in the pulse-echo field (PEF) along the direction transverse to the ultrasound propagation direction. This may be exploited to extend flow investigations toward multidimensional estimates. In this paper, the TOs are coupled with the transmission of plane waves (PWs) to reconstruct high-framerate RF images with bidirectional oscillations in the pulse-echo field. Such RF images are then processed by a 2-D phase-based displacement estimator to produce 2-D vector flow maps at thousands of frames per second. First, the capability of generating TOs after PW transmissions was thoroughly investigated by varying the lateral wavelength, the burst length, and the transmission frequency. Over the entire region of interest, the generated lateral wavelengths, compared with the designed ones, presented bias and standard deviation of -3.3 ± 5.7% and 10.6 ± 7.4% in simulations and experiments, respectively. The performance of the ultrafast vector flow mapping method was also assessed by evaluating the differences between the estimated velocities and the expected ones. Both simulations and experiments show overall biases lower than 20% when varying the beam-to-flow angle, the peak velocity, and the depth of interest. In vivo applications of the method on the common carotid and the brachial arteries are also presented.

  16. Bifurcation physics of magnetic islands and stochasticity explored by heat pulse propagation studies in toroidal plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ida, K.; Kobayashi, T.; Yoshinuma, M.

    Bifurcation physics of the magnetic island was investigated using the heat pulse propagation technique produced by the modulation of electron cyclotron heating. There are two types of bifurcation phenomena observed in LHD and DIII-D. One is a bifurcation of the magnetic topology between nested and stochastic fields. The nested state is characterized by the bi-directional (inward and outward) propagation of the heat pulse with slow propagation speed. The stochastic state is characterized by the fast propagation of the heat pulse with electron temperature flattening. The other bifurcation is between magnetic island with larger thermal diffusivity and that with smaller thermalmore » diffusivity. The damping of toroidal flow is observed at the O-point of the magnetic island both in helical plasmas and in tokamak plasmas during a mode locking phase with strong flow shears at the boundary of the magnetic island. Associated with the stochastization of the magnetic field, the abrupt damping of toroidal flow is observed in LHD. The toroidal flow shear shows a linear decay, while the ion temperature gradient shows an exponential decay. Lastly, this observation suggests that this flow damping is due to the change in the non-diffusive term of momentum transport.« less

  17. Involvement of Thalamus in Initiation of Epileptic Seizures Induced by Pilocarpine in Mice

    PubMed Central

    Li, Yong-Hua; Li, Jia-Jia; Lu, Qin-Chi; Gong, Hai-Qing; Liang, Pei-Ji

    2014-01-01

    Studies have suggested that thalamus is involved in temporal lobe epilepsy, but the role of thalamus is still unclear. We obtained local filed potentials (LFPs) and single-unit activities from CA1 of hippocampus and parafascicular nucleus of thalamus during the development of epileptic seizures induced by pilocarpine in mice. Two measures, redundancy and directionality index, were used to analyze the electrophysiological characters of neuronal activities and the information flow between thalamus and hippocampus. We found that LFPs became more regular during the seizure in both hippocampus and thalamus, and in some cases LFPs showed a transient disorder at seizure onset. The variation tendency of the peak values of cross-correlation function between neurons matched the variation tendency of the redundancy of LFPs. The information tended to flow from thalamus to hippocampus during seizure initiation period no matter what the information flow direction was before the seizure. In some cases the information flow was symmetrically bidirectional, but none was found in which the information flowed from hippocampus to thalamus during the seizure initiation period. In addition, inactivation of thalamus by tetrodotoxin (TTX) resulted in a suppression of seizures. These results suggest that thalamus may play an important role in the initiation of epileptic seizures. PMID:24778885

  18. Bifurcation physics of magnetic islands and stochasticity explored by heat pulse propagation studies in toroidal plasmas

    DOE PAGES

    Ida, K.; Kobayashi, T.; Yoshinuma, M.; ...

    2016-07-29

    Bifurcation physics of the magnetic island was investigated using the heat pulse propagation technique produced by the modulation of electron cyclotron heating. There are two types of bifurcation phenomena observed in LHD and DIII-D. One is a bifurcation of the magnetic topology between nested and stochastic fields. The nested state is characterized by the bi-directional (inward and outward) propagation of the heat pulse with slow propagation speed. The stochastic state is characterized by the fast propagation of the heat pulse with electron temperature flattening. The other bifurcation is between magnetic island with larger thermal diffusivity and that with smaller thermalmore » diffusivity. The damping of toroidal flow is observed at the O-point of the magnetic island both in helical plasmas and in tokamak plasmas during a mode locking phase with strong flow shears at the boundary of the magnetic island. Associated with the stochastization of the magnetic field, the abrupt damping of toroidal flow is observed in LHD. The toroidal flow shear shows a linear decay, while the ion temperature gradient shows an exponential decay. Lastly, this observation suggests that this flow damping is due to the change in the non-diffusive term of momentum transport.« less

  19. Adult attachment and early parental experiences in patients with Crohn's disease.

    PubMed

    Agostini, Alessandro; Rizzello, Fernando; Ravegnani, Gianni; Gionchetti, Paolo; Tambasco, Rosy; Straforini, Giulia; Ercolani, Mauro; Campieri, Massimo

    2010-01-01

    Crohn's disease (CD) is a chronic, relapsing and remitting inflammatory bowel disease. The relationship of attachment to the illness is considered to be bidirectional. The authors investigated aspects of this bidirectional relationship. A group of 102 patients with CD and 306 healthy subjects filled out the Attachment Style Questionnaire and the Parental Bonding Instrument. Patients with CD exhibit a predominantly insecure attachment and perceived their parents' behaviors as characterized by low maternal care and high paternal overprotection. The evaluation of attachment style and early parental experiences in patients with CD may shed light on the bidirectional relationship between attachment and illness. These findings may confirm the bidirectional relationship between insecure attachment and chronic illness.

  20. Bidirectional Modulation of Substantia Nigra Activity by Motivational State

    PubMed Central

    Rossi, Mark A.; Fan, David; Barter, Joseph W.; Yin, Henry H.

    2013-01-01

    A major output nucleus of the basal ganglia is the substantia nigra pars reticulata, which sends GABAergic projections to brainstem and thalamic nuclei. The GABAergic (GABA) neurons are reciprocally connected with nearby dopaminergic neurons, which project mainly to the basal ganglia, a set of subcortical nuclei critical for goal-directed behaviors. Here we examined the impact of motivational states on the activity of GABA neurons in the substantia nigra pars reticulata and the neighboring dopaminergic (DA) neurons in the pars compacta. Both types of neurons show short-latency bursts to a cue predicting a food reward. As mice became sated by repeated consumption of food pellets, one class of neurons reduced cue-elicited firing, whereas another class of neurons progressively increased firing. Extinction or pre-feeding just before the test session dramatically reduced the phasic responses and their motivational modulation. These results suggest that signals related to the current motivational state bidirectionally modulate behavior and the magnitude of phasic response of both DA and GABA neurons in the substantia nigra. PMID:23936522

  1. Detailed validation of the bidirectional effect in various Case 1 waters for application to Ocean Color imagery

    NASA Astrophysics Data System (ADS)

    Voss, K. J.; Morel, A.; Antoine, D.

    2007-06-01

    The radiance viewed from the ocean depends on the illumination and viewing geometry along with the water properties and this variation is called the bidirectional effect, or BRDF of the water. This BRDF depends on the inherent optical properties of the water, including the volume scattering function, and is important when comparing data from different satellite sensors. The current model by Morel et al. (2002) depends on modeled water parameters, thus must be carefully validated. In this paper we combined upwelling radiance distribution data from several cruises, in varied water types and with a wide range of solar zenith angles. We found that the average error of the model, when compared to the data was less than 1%, while the RMS difference between the model and data was on the order of 0.02-0.03. This is well within the statistical noise of the data, which was on the order of 0.04-0.05, due to environmental noise sources such as wave focusing.

  2. How much is it going to cost me? Bidirectional relations between adolescents' moral personality and prosocial behavior.

    PubMed

    Padilla-Walker, Laura M; Fraser, Ashley M

    2014-10-01

    The current study examined bidirectional relations between adolescents' moral personality (prosocial values, self-regulation, and sympathy) and low- and high-cost prosocial behavior toward strangers. Participants included 682 adolescents (M age of child = 14.31, SD = 1.07, 50% female) who participated at two time points, approximately one year apart. Cross-lag analyses suggested that adolescents' values were associated with both low- and high-cost prosocial behavior one year later, self-regulation was associated with high-cost prosocial behavior, and sympathy was associated with low-cost prosocial behavior. Findings also suggested that low-cost prosocial behavior was associated with sympathy one year later, and high-cost prosocial behavior was associated with values. Discussion focuses on reciprocal relations between moral personality and prosocial behavior, and the need to consider a more multidimensional approach to prosocial development during adolescence. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  3. Bidirectional quantum teleportation of unknown photons using path-polarization intra-particle hybrid entanglement and controlled-unitary gates via cross-Kerr nonlinearity

    NASA Astrophysics Data System (ADS)

    Heo, Jino; Hong, Chang-Ho; Lim, Jong-In; Yang, Hyung-Jin

    2015-05-01

    We propose an arbitrary controlled-unitary (CU) gate and a bidirectional quantum teleportation (BQTP) scheme. The proposed CU gate utilizes photonic qubits (photons) with cross-Kerr nonlinearities (XKNLs), X-homodyne detectors, and linear optical elements, and consists of the consecutive operation of a controlled-path (C-path) gate and a gathering-path (G-path) gate. It is almost deterministic and feasible with current technology when a strong coherent state and weak XKNLs are employed. Based on the CU gate, we present a BQTP scheme that simultaneously teleports two unknown photons between distant users by transmitting only one photon in a path-polarization intra-particle hybrid entangled state. Consequently, it is possible to experimentally implement BQTP with a certain success probability using the proposed CU gate. Project supported by the Ministry of Science, ICT&Future Planning, Korea, under the C-ITRC (Convergence Information Technology Research Center) Support program (NIPA-2013-H0301-13-3007) supervised by the National IT Industry Promotion Agency.

  4. [Depression and epilepsy : Two clinical pictures with common causes?].

    PubMed

    Borgmann, M; Holtkamp, M; Adli, M; Behr, J

    2016-07-01

    Epilepsy and depressive disorders show a high rate of comorbidity. Thus, neurobiological similarities and a bidirectional relationship in terms of pathogenesis have been suggested. The aim of this article is to present the common neurobiological features of both disorders, to characterize the bidirectional relationship and to provide an overview of therapeutic consequences. A review of the current literature and evaluation of studies on the topics of depression and epilepsy are presented. Epilepsy and depression share common neurobiological features. In epileptic patients depression should be diagnosed early and reliably as the successful treatment has a great influence on the prognosis, quality of life and suicide risk in these individuals. In therapeutic doses, antidepressive medication with noradrenergic and specific serotonergic antidepressants (NaSSA) or selective serotonin reuptake inhibitors (SSRI) imparts no clinically relevant epileptogenic potential; however, it increases the quality of life and could have anticonvulsant effects in patients with epilepsy. Clomipramine, bupropion and maprotiline, however, should not be administered to patients with epilepsy as they are known to lower the seizure threshold.

  5. Mediation of the bidirectional relations between obesity and depression among women.

    PubMed

    Vittengl, Jeffrey R

    2018-06-01

    Past research established that obesity increases risk for development of depression, and depression increases risk for development of obesity. The current study tested physical impairment (difficulty with instrumental activities of daily living), social dysfunction (low social support and high social strain), and emotional eating (using food to cope with stress) as mediators of the bidirectional, longitudinal relations between depression and obesity. A national sample of mid-life adults in the United States (N = 7108) was assessed at three time points over 18 years. Depression predicted increases in obesity, and obesity predicted increases in depression, for women but not for men. Among women, path analyses revealed that physical impairment, social dysfunction, and emotional eating mediated development of obesity from depression, and that physical impairment and emotional eating mediated development of depression from obesity. These results suggest that prevention or treatment of obesity-linked depression and depression-linked obesity in women may need to address multiple connections between these disorders. Copyright © 2018 Elsevier B.V. All rights reserved.

  6. REVIEW ARTICLE: Hither and yon: a review of bi-directional microtubule-based transport

    NASA Astrophysics Data System (ADS)

    Gross, Steven P.

    2004-06-01

    Active transport is critical for cellular organization and function, and impaired transport has been linked to diseases such as neuronal degeneration. Much long distance transport in cells uses opposite polarity molecular motors of the kinesin and dynein families to move cargos along microtubules. It is increasingly clear that many cargos are moved by both sets of motors, and frequently reverse course. This review compares this bi-directional transport to the more well studied uni-directional transport. It discusses some bi-directionally moving cargos, and critically evaluates three different physical models for how such transport might occur. It then considers the evidence for the number of active motors per cargo, and how the net or average direction of transport might be controlled. The likelihood of a complex linking the activities of kinesin and dynein is also discussed. The paper concludes by reviewing elements of apparent universality between different bi-directionally moving cargos and by briefly considering possible reasons for the existence of bi-directional transport.

  7. Anti-Noise Bidirectional Quantum Steganography Protocol with Large Payload

    NASA Astrophysics Data System (ADS)

    Qu, Zhiguo; Chen, Siyi; Ji, Sai; Ma, Songya; Wang, Xiaojun

    2018-06-01

    An anti-noise bidirectional quantum steganography protocol with large payload protocol is proposed in this paper. In the new protocol, Alice and Bob enable to transmit classical information bits to each other while teleporting secret quantum states covertly. The new protocol introduces the bidirectional quantum remote state preparation into the bidirectional quantum secure communication, not only to expand secret information from classical bits to quantum state, but also extract the phase and amplitude values of secret quantum state for greatly enlarging the capacity of secret information. The new protocol can also achieve better imperceptibility, since the eavesdropper can hardly detect the hidden channel or even obtain effective secret quantum states. Comparing with the previous quantum steganography achievements, due to its unique bidirectional quantum steganography, the new protocol can obtain higher transmission efficiency and better availability. Furthermore, the new algorithm can effectively resist quantum noises through theoretical analysis. Finally, the performance analysis proves the conclusion that the new protocol not only has good imperceptibility, high security, but also large payload.

  8. Anti-Noise Bidirectional Quantum Steganography Protocol with Large Payload

    NASA Astrophysics Data System (ADS)

    Qu, Zhiguo; Chen, Siyi; Ji, Sai; Ma, Songya; Wang, Xiaojun

    2018-03-01

    An anti-noise bidirectional quantum steganography protocol with large payload protocol is proposed in this paper. In the new protocol, Alice and Bob enable to transmit classical information bits to each other while teleporting secret quantum states covertly. The new protocol introduces the bidirectional quantum remote state preparation into the bidirectional quantum secure communication, not only to expand secret information from classical bits to quantum state, but also extract the phase and amplitude values of secret quantum state for greatly enlarging the capacity of secret information. The new protocol can also achieve better imperceptibility, since the eavesdropper can hardly detect the hidden channel or even obtain effective secret quantum states. Comparing with the previous quantum steganography achievements, due to its unique bidirectional quantum steganography, the new protocol can obtain higher transmission efficiency and better availability. Furthermore, the new algorithm can effectively resist quantum noises through theoretical analysis. Finally, the performance analysis proves the conclusion that the new protocol not only has good imperceptibility, high security, but also large payload.

  9. Bidirectional negative differential thermal resistance phenomenon and its physical mechanism in the Frenkel-Kontorova lattices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jianqiang, Zhang; Linru, Nie, E-mail: lrnie@163.com; Chongyang, Chen

    2016-07-15

    Thermal conduction of the Frenkel-Kontorova (FK) lattices with interfacial coupling is investigated numerically. The results indicate that: (i) For appropriate lattice periods, as the system is symmetric, a bidirectional negative differential thermal resistance (NDTR) phenomenon will appear. If the system is asymmetric, the bidirectional NDTR is gradually converted into an unidirectional NDTR. (ii) The bidirectional NDTR phenomenon effect also depends on the period of the FK lattice as the other parameters remains unchanged. With the increment of the lattice period, the bidirectional NDTR will gradually disappear. (iii) From a stochastic dynamics point of view, thermal transport properties of the systemmore » are determined by the competition between the two types of thermal conduction: one comes from the collusion between atoms, the other is due to the elastic coupling between atoms. For the smaller lattice periods, the former type of thermal conduction occupies the dominating position and the NDTR effect will appear.« less

  10. Günther Tulip inferior vena cava filter retrieval using a bidirectional loop-snare technique.

    PubMed

    Ross, Jordan; Allison, Stephen; Vaidya, Sandeep; Monroe, Eric

    2016-01-01

    Many advanced techniques have been reported in the literature for difficult Günther Tulip filter removal. This report describes a bidirectional loop-snare technique in the setting of a fibrin scar formation around the filter leg anchors. The bidirectional loop-snare technique allows for maximal axial tension and alignment for stripping fibrin scar from the filter legs, a commonly encountered complication of prolonged dwell times.

  11. The Pavlovian analysis of instrumental conditioning.

    PubMed

    Gormezano, I; Tait, R W

    1976-01-01

    An account was given of the development within the Russian literature of a uniprocess formulation of classical and instrumental conditioning, known as the bidirectional conditioning hypothesis. The hypothesis purports to offer a single set of Pavlovian principles to account for both paradigms, based upon a neural model which assumes that bidirectional (forward and backward) connections are formed in both calssical and instrumental conditioning situations. In instrumental conditioning, the bidirectional connections are hypothesized to be simply more complex than those in classical conditioning, and any differences in empirical functions are presumed to lie not in difference in mechanism, but in the strength of the forward and backward connections. Although bidirectional connections are assumed to develop in instrumental conditioning, the experimental investigation of the bidirectional conditioning hypothesis has been essentially restricted to the classical conditioning operations of pairing two CSs (sensory preconditioning training), a US followed by a CS (backward conditioning training) and two USs. However, the paradigm involving the pairing of two USs, because of theoretical and analytical considerations, is the one most commonly employed by Russian investigators. The results of an initial experiment involving the pairing of two USs, and reference to the results of a more extensive investigation, leads us to tentatively question the validity of the bidirectional conditioning account of instrumental conditioning.

  12. BiPOD Arthroscopic Acromioclavicular Repair Restores Bidirectional Stability.

    PubMed

    De Beer, Joe; Schaer, Michael; Latendresse, Kim; Raniga, Sumit; Moor, Beat K; Zumstein, Matthias A

    2017-01-01

    Stabilizing the acromioclavicular joint in the vertical and horizontal planes is challenging, and most current techniques do not reliably achieve this goal. The BiPOD repair is an arthroscopically assisted procedure performed with image intensifier guidance that reconstructs the coracoclavicular ligaments as well as the acromioclavicular ligaments to achieve bidirectional stability. Repair is achieved with a combination of 2-mm FiberTape (Arthrex, Naples, Florida) and 20-mm Poly-Tape (Neoligaments, Leeds, England) to achieve rigid repair, prevent bone abrasion, and promote tissue ingrowth. This study is a prospective review of the first 6 patients treated for high-grade acute acromioclavicular injury with the BiPOD technique. The study included 6 men who were 21 to 36 years old (mean, 27 years). At 6-month follow-up, complications were recorded and radiographic analysis was used to determine the coracoclavicular distance for vertical reduction and the amount of acromioclavicular translation on the Alexander axillary view was used to determine horizontal reduction. One patient had a superficial infection over the tape knot. The difference in coracoclavicular distance between the operated side and the uninvolved side was 9±2 mm preoperatively and 0.3±2 mm at 6-month follow-up. On Alexander axillary view, all 6 patients showed stable reduction, which is defined as a clavicle that is in line with the acromion. The findings show that BiPOD acromioclavicular reconstruction restores bidirectional stability of the acromioclavicular joint at 6 months. [Orthopedics. 2017; 40(1):e35-e43.]. Copyright 2016, SLACK Incorporated.

  13. Tidal reversal and flow velocities using temperature and specific conductance in a small wetland creek

    NASA Astrophysics Data System (ADS)

    Eaton, Timothy T.

    2016-11-01

    Characterizing flow dynamics in very small tidal creeks is complicated and not well suited to methods developed for upland streams or coastal estuaries, due to low flows, bidirectionality and shallow waters. Simple instrumentation enables thermal and salinity signals to be used to observe flow directions and estimate velocities in these settings. Using multiple inexpensive sensors over 500 m along a tidally influenced wetland creek, I demonstrate how advection of temperature and specific conductance pulses reveal flood and ebb tides and the temporary reversal of flow by warmer, estuarine water from the receiving embayment. The sequential rise of temperature upstream was most evident under hot and dry conditions, after daily peak air temperatures of 25 °C or above, and was subdued or disrupted under cooler or rainy conditions in summertime. Changes in specific conductance at successive sites upstream were less susceptible to environmental influences and confirm tidal flood velocity of between 0.07 and 0.37 m/s. The tidally-induced flow reversal suggests that periodic high tide conditions can interfere with rapid dispersal of pollution discharges, such as from the combined sewer overflow (CSO) located upstream of the studied creek reach. This low-cost approach of temperature and specific conductance sensing in vegetated coastal wetlands where access, precise elevation control and creek discharge measurements are difficult, provides a simple way of tracking water masses when sufficient contrast exists between water sources.

  14. The Caltech experimental investigation of fast 3D non-equilbrium dynamics: an overview

    NASA Astrophysics Data System (ADS)

    Bellan, Paul; Shikama, Taiichi; Chai, Kilbyoung; Ha, Bao; Chaplin, Vernon; Kendall, Mark; Moser, Auna; Stenson, Eve; Tobin, Zachary; Zhai, Xiang

    2012-10-01

    The formation and dynamics of writhing, plasma-filled, twisted open magnetic flux tubes is being investigated using pulsed-power laboratory experiments. This work is relevant to solar corona loops, astrophysical jets, spheromak formation, and open field lines in tokamaks and RFP's. MHD forces have been observed to drive fast axial plasma flows into the flux tube from the boundary it intercepts. These flows fill the flux tube with plasma while simultaneously injecting linked frozen-in azimuthal flux; helicity injection is thus associated with mass injection. Recent results include observation of a secondary instability (Rayleigh-Taylor driven by the effective gravity of an exponentially growing kink mode), color-coded plasmas manifesting bidirectional axial flows in a geometry similar to a solar corona loop, and spectroscopic measurements of the internal vector magnetic field. Experiments underway include investigating how an external magnetic field straps down a solar loop, investigation of the details of the Rayleigh-Taylor instability, development of a fast EUV movie camera, increasing the jet velocity, excitation of Alfven waves, and investigating 3D magnetic reconnection.

  15. Aortic Blood Flow Reversal Determines Renal Function: Potential Explanation for Renal Dysfunction Caused by Aortic Stiffening in Hypertension.

    PubMed

    Hashimoto, Junichiro; Ito, Sadayoshi

    2015-07-01

    Aortic stiffness determines the glomerular filtration rate (GFR) and predicts the progressive decline of the GFR. However, the underlying pathophysiological mechanism remains obscure. Recent evidence has shown a close link between aortic stiffness and the bidirectional (systolic forward and early diastolic reverse) flow characteristics. We hypothesized that the aortic stiffening-induced renal dysfunction is attributable to altered central flow dynamics. In 222 patients with hypertension, Doppler velocity waveforms were recorded at the proximal descending aorta to calculate the reverse/forward flow ratio. Tonometric waveforms were recorded to measure the carotid-femoral (aortic) and carotid-radial (peripheral) pulse wave velocities, to estimate the aortic pressure from the radial waveforms, and to compute the aortic characteristic impedance. In addition, renal hemodynamics was evaluated by duplex ultrasound. The estimated GFR was inversely correlated with the aortic pulse wave velocity, reverse/forward flow ratio, pulse pressure, and characteristic impedance, whereas it was not correlated with the peripheral pulse wave velocity or mean arterial pressure. The association between aortic pulse wave velocity and estimated GFR was independent of age, diabetes mellitus, hypercholesterolemia, and antihypertensive medication. However, further adjustment for the aortic reverse/forward flow ratio and pulse pressure substantially weakened this association, and instead, the reverse/forward flow ratio emerged as the strongest determinant of estimated GFR (P=0.001). A higher aortic reverse/forward flow ratio was also associated with lower intrarenal forward flow velocities. These results suggest that an increase in aortic flow reversal (ie, retrograde flow from the descending thoracic aorta toward the aortic arch), caused by aortic stiffening and impedance mismatch, reduces antegrade flow into the kidney and thereby deteriorates renal function. © 2015 American Heart Association, Inc.

  16. Multicasting mesh AER: a scalable assembly approach for reconfigurable neuromorphic structured AER systems. Application to ConvNets.

    PubMed

    Zamarreno-Ramos, C; Linares-Barranco, A; Serrano-Gotarredona, T; Linares-Barranco, B

    2013-02-01

    This paper presents a modular, scalable approach to assembling hierarchically structured neuromorphic Address Event Representation (AER) systems. The method consists of arranging modules in a 2D mesh, each communicating bidirectionally with all four neighbors. Address events include a module label. Each module includes an AER router which decides how to route address events. Two routing approaches have been proposed, analyzed and tested, using either destination or source module labels. Our analyses reveal that depending on traffic conditions and network topologies either one or the other approach may result in better performance. Experimental results are given after testing the approach using high-end Virtex-6 FPGAs. The approach is proposed for both single and multiple FPGAs, in which case a special bidirectional parallel-serial AER link with flow control is exploited, using the FPGA Rocket-I/O interfaces. Extensive test results are provided exploiting convolution modules of 64 × 64 pixels with kernels with sizes up to 11 × 11, which process real sensory data from a Dynamic Vision Sensor (DVS) retina. One single Virtex-6 FPGA can hold up to 64 of these convolution modules, which is equivalent to a neural network with 262 × 10(3) neurons and almost 32 million synapses.

  17. Double Outlet Right Ventricle With Intact Ventricular Septum: Avulsion or Exclusion.

    PubMed

    Menon, Sabarinath; Kumar, C J Ashok; Mathew, Thomas; Venkateshwarn, S; Jayakumar, K; Dharan, Baiju S

    2016-03-01

    Double outlet right ventricle (DORV) is almost always associated with a ventricular septal defect. The variant of DORV with intact ventricular septum is very uncommon and may be associated with fetal demise or death immediately after birth. Reports of successful palliation of these patients to the stage of superior cavopulmonary anastomosis (bidirectional Glenn shunt) are rare. We describe the case of a child with DORV with intact ventricular septum who underwent successful palliation. This condition often provides a diagnostic, interventional, and surgical challenge. Patients generally require either balloon atrial septostomy or surgical atrial septectomy for survival, with the addition of a Blalock-Tausig shunt or pulmonary artery band depending on the pulmonary blood flow. Very few patients survive to a Glenn procedure. For those who do survive, a decision must be made regarding the management of the hypertensive and hypoplastic left ventricle (LV) and associated mitral regurgitation. The LV can be excluded by either mitral valve avulsion or closure (exclusion) of the mitral valve with a patch. The choice of the technique should be carefully made and depends in part on the size of the LV. In our patient, who was successfully palliated by bidirectional Glenn shunt, the LV was managed by means of mitral valve avulsion. © The Author(s) 2015.

  18. Bidirectional transport model of morphogen gradient formation via cytonemes

    NASA Astrophysics Data System (ADS)

    Bressloff, Paul C.; Kim, Hyunjoong

    2018-03-01

    Morphogen protein gradients play an important role in the spatial regulation of patterning during embryonic development. The most commonly accepted mechanism for gradient formation is diffusion from a source combined with degradation. Recently, there has been growing interest in an alternative mechanism, which is based on the direct delivery of morphogens along thin, actin-rich cellular extensions known as cytonemes. In this paper, we develop a bidirectional motor transport model for the flux of morphogens along cytonemes, linking a source cell to a one-dimensional array of target cells. By solving the steady-state transport equations, we show how a morphogen gradient can be established, and explore how the mean velocity of the motors affects properties of the morphogen gradient such as accumulation time and robustness. In particular, our analysis suggests that in order to achieve robustness with respect to changes in the rate of synthesis of morphogen, the mean velocity has to be negative, that is, retrograde flow or treadmilling dominates. Thus the potential targeting precision of cytonemes comes at an energy cost. We then study the effects of non-uniformly allocating morphogens to the various cytonemes projecting from a source cell. This competition for resources provides a potential regulatory control mechanism not available in diffusion-based models.

  19. Synchronization and bidirectional communication without delay line using strong mutually coupled semiconductor lasers

    NASA Astrophysics Data System (ADS)

    Li, Guang-Hui; Wang, An-Bang; Feng, Ye; Wang, Yang

    2010-07-01

    This paper numerically demonstrates synchronization and bidirectional communication without delay line by using two semiconductor lasers with strong mutual injection in a face-to-face configuration. These results show that both of the two lasers' outputs synchronize with their input chaotic carriers. In addition, simulations demonstrate that this kind of synchronization can be used to realize bidirectional communications without delay line. Further studies indicate that within a small deviation in message amplitudes of two sides (±6%), the message can be extracted with signal-noise-ratio more than 10 dB; and the signal-noise-ratio is extremely sensitive to the message rates mismatch of two sides, which may be used as a key of bidirectional communication.

  20. Microwave impedance matching strategies of an applicator supplied by a bi-directional magnetron waveguide launcher.

    PubMed

    Roussy, Georges; Kongmark, Nils

    2003-01-01

    It is shown that a bi-directional waveguide launcher can be used advantageously for reducing the reflection coefficient mismatch of an input impedance of an applicator. In a simple bi-directional waveguide launcher, the magnetron is placed in the waveguide and generates a nominal field distribution with significant output impedance in both directions of the waveguide. If a standing wave is tolerated in the torus, which connects the launcher and the applicator, the power transfer from the magnetron to the applicator can be optimal, without using special matching devices. It is also possible to match the bi-directional launcher with two inductance stubs near the antenna of the magnetron and use them for supplying a two-input applicator without reflection.

  1. Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway.

    PubMed

    Mori, Masayuki X; Itsuki, Kyohei; Hase, Hideharu; Sawamura, Seishiro; Kurokawa, Tatsuki; Mori, Yasuo; Inoue, Ryuji

    2015-01-01

    Transient receptor potential canonical (TRPC) channels are Ca(2+)-permeable, nonselective cation channels that carry receptor-operated Ca(2+) currents (ROCs) triggered by receptor-induced, phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]. Within the vasculature, TRPC channel ROCs contribute to smooth muscle cell depolarization, vasoconstriction, and vascular remodeling. However, TRPC channel ROCs exhibit a variable response to receptor-stimulation, and the regulatory mechanisms governing TRPC channel activity remain obscure. The variability of ROCs may be explained by their complex regulation by PI(4,5)P2 and its metabolites, which differentially affect TRPC channel activity. To resolve the complex regulation of ROCs, the use of voltage-sensing phosphoinositide phosphatases and model simulation have helped to reveal the time-dependent contribution of PI(4,5)P2 and the possible role of PI(4,5)P2 in the regulation of ROCs. These approaches may provide unprecedented insight into the dynamics of PI(4,5)P2 regulation of TRPC channels and the fundamental mechanisms underlying transmembrane ion flow. Within that context, we summarize the regulation of TRPC channels and their coupling to receptor-mediated signaling, as well as the application of voltage-sensing phosphoinositide phosphatases to this research. We also discuss the controversial bidirectional effects of PI(4,5)P2 using a model simulation that could explain the complicated effects of PI(4,5)P2 on different ROCs.

  2. Analysis and Application of Microgrids

    NASA Astrophysics Data System (ADS)

    Yue, Lu

    New trends of generating electricity locally and utilizing non-conventional or renewable energy sources have attracted increasing interests due to the gradual depletion of conventional fossil fuel energy sources. The new type of power generation is called Distributed Generation (DG) and the energy sources utilized by Distributed Generation are termed Distributed Energy Sources (DERs). With DGs embedded in the distribution networks, they evolve from passive distribution networks to active distribution networks enabling bidirectional power flows in the networks. Further incorporating flexible and intelligent controllers and employing future technologies, active distribution networks will turn to a Microgrid. A Microgrid is a small-scale, low voltage Combined with Heat and Power (CHP) supply network designed to supply electrical and heat loads for a small community. To further implement Microgrids, a sophisticated Microgrid Management System must be integrated. However, due to the fact that a Microgrid has multiple DERs integrated and is likely to be deregulated, the ability to perform real-time OPF and economic dispatch with fast speed advanced communication network is necessary. In this thesis, first, problems such as, power system modelling, power flow solving and power system optimization, are studied. Then, Distributed Generation and Microgrid are studied and reviewed, including a comprehensive review over current distributed generation technologies and Microgrid Management Systems, etc. Finally, a computer-based AC optimization method which minimizes the total transmission loss and generation cost of a Microgrid is proposed and a wireless communication scheme based on synchronized Code Division Multiple Access (sCDMA) is proposed. The algorithm is tested with a 6-bus power system and a 9-bus power system.

  3. Discontinuous Galerkin modeling of the Columbia River's coupled estuary-plume dynamics

    NASA Astrophysics Data System (ADS)

    Vallaeys, Valentin; Kärnä, Tuomas; Delandmeter, Philippe; Lambrechts, Jonathan; Baptista, António M.; Deleersnijder, Eric; Hanert, Emmanuel

    2018-04-01

    The Columbia River (CR) estuary is characterized by high river discharge and strong tides that generate high velocity flows and sharp density gradients. Its dynamics strongly affects the coastal ocean circulation. Tidal straining in turn modulates the stratification in the estuary. Simulating the hydrodynamics of the CR estuary and plume therefore requires a multi-scale model as both shelf and estuarine circulations are coupled. Such a model has to keep numerical dissipation as low as possible in order to correctly represent the plume propagation and the salinity intrusion in the estuary. Here, we show that the 3D baroclinic discontinuous Galerkin finite element model SLIM 3D is able to reproduce the main features of the CR estuary-to-ocean continuum. We introduce new vertical discretization and mode splitting that allow us to model a region characterized by complex bathymetry and sharp density and velocity gradients. Our model takes into account the major forcings, i.e. tides, surface wind stress and river discharge, on a single multi-scale grid. The simulation period covers the end of spring-early summer of 2006, a period of high river flow and strong changes in the wind regime. SLIM 3D is validated with in-situ data on the shelf and at multiple locations in the estuary and compared with an operational implementation of SELFE. The model skill in the estuary and on the shelf indicate that SLIM 3D is able to reproduce the key processes driving the river plume dynamics, such as the occurrence of bidirectional plumes or reversals of the inner shelf coastal currents.

  4. Monitoring Bio-Optical Processes Using NPP-VIIRS and MODIS-Aqua Ocean Color Products

    DTIC Science & Technology

    2013-01-01

    shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number...account for satellite sensor and solar zenith angles. Additionally, the Bidirectional Reflectance Distribution Function ( BRDF ) of the water particles is...similarly dependent on satellite and solar zenith and azimuth angles 4 . The influence of BRDF is more pronounced in a high scattering environment

  5. Use of asymmetric bidirectional catheters with different curvature radius for catheter ablation of cardiac arrhythmias.

    PubMed

    Mantziari, Lilian; Suman-Horduna, Irina; Gujic, Marko; Jones, David G; Wong, Tom; Markides, Vias; Foran, John P; Ernst, Sabine

    2013-06-01

    The impact of recently introduced asymmetric bidirectional ablation catheters on procedural parameters and acute success rates of ablation procedures is unknown. We retrospectively analyzed data regarding ablations using a novel bidirectional catheter in a tertiary cardiac center and compared these in 1:5 ratio with a control group of procedures matched for age, gender, operator, and ablation type. A total of 50 cases and 250 controls of median age 60 (50-68) years were studied. Structural heart disease was equally prevalent in both groups (39%) while history of previous ablations was more common in the study arm (54% vs 30%, P = 0.001). Most of the ablation cases were for atrial fibrillation (46%), followed by atrial tachycardia (28%), supraventricular tachycardia (12%), and ventricular tachycardia (14%). Median procedure duration was 128 (52-147) minutes with the bidirectional, versus 143 (105-200) minutes with the conventional catheter (P = 0.232), and median fluoroscopy time was 17 (10-34) minutes versus 23 (12-39) minutes, respectively (P = 0.988). There was a trend toward a lower procedure duration for the atrial tachycardia ablations, 89 (52-147) minutes versus 130 (100-210) minutes, P = 0.064. The procedure was successfully completed in 96% of the bidirectional versus 84% of the control cases (P = 0.151). A negative correlation was observed between the relative fluoroscopy duration and the case number (r = -0.312, P = 0.028), reflecting the learning curve for the bidirectional catheter. The introduction of the bidirectional catheter resulted in no prolongation of procedure parameters and similar success rates, while there was a trend toward a lower procedure duration for atrial tachycardia ablations. ©2013, The Authors. Journal compilation ©2013 Wiley Periodicals, Inc.

  6. Bidirectional optical bistability in a dual-pumped erbium doped fiber ring laser.

    PubMed

    Lai, W J; Shum, P; Binh, L

    2004-11-15

    We investigate bidirectional optical wave propagations in a dual-pumped erbium doped fiber ring laser without isolator, and observe optical bistability behaviors. Consequently, we propose and construct a NOLM-NALM fiber ring laser to demonstrate and exploit this bidirectional optical bistability phenomenon in optical switching by introducing two tunable variable ratio couplers in the system. Numerical analyses based on the proposed laser structure have also been demonstrated corroborated with the experimental results.

  7. Effective Connectivity of Cortical Sensorimotor Networks During Finger Movement Tasks: A Simultaneous fNIRS, fMRI, EEG Study.

    PubMed

    Anwar, A R; Muthalib, M; Perrey, S; Galka, A; Granert, O; Wolff, S; Heute, U; Deuschl, G; Raethjen, J; Muthuraman, Muthuraman

    2016-09-01

    Recently, interest has been growing to understand the underlying dynamic directional relationship between simultaneously activated regions of the brain during motor task performance. Such directionality analysis (or effective connectivity analysis), based on non-invasive electrophysiological (electroencephalography-EEG) and hemodynamic (functional near infrared spectroscopy-fNIRS; and functional magnetic resonance imaging-fMRI) neuroimaging modalities can provide an estimate of the motor task-related information flow from one brain region to another. Since EEG, fNIRS and fMRI modalities achieve different spatial and temporal resolutions of motor-task related activation in the brain, the aim of this study was to determine the effective connectivity of cortico-cortical sensorimotor networks during finger movement tasks measured by each neuroimaging modality. Nine healthy subjects performed right hand finger movement tasks of different complexity (simple finger tapping-FT, simple finger sequence-SFS, and complex finger sequence-CFS). We focused our observations on three cortical regions of interest (ROIs), namely the contralateral sensorimotor cortex (SMC), the contralateral premotor cortex (PMC) and the contralateral dorsolateral prefrontal cortex (DLPFC). We estimated the effective connectivity between these ROIs using conditional Granger causality (GC) analysis determined from the time series signals measured by fMRI (blood oxygenation level-dependent-BOLD), fNIRS (oxygenated-O2Hb and deoxygenated-HHb hemoglobin), and EEG (scalp and source level analysis) neuroimaging modalities. The effective connectivity analysis showed significant bi-directional information flow between the SMC, PMC, and DLPFC as determined by the EEG (scalp and source), fMRI (BOLD) and fNIRS (O2Hb and HHb) modalities for all three motor tasks. However the source level EEG GC values were significantly greater than the other modalities. In addition, only the source level EEG showed a significantly greater forward than backward information flow between the ROIs. This simultaneous fMRI, fNIRS and EEG study has shown through independent GC analysis of the respective time series that a bi-directional effective connectivity occurs within a cortico-cortical sensorimotor network (SMC, PMC and DLPFC) during finger movement tasks.

  8. Bidirectional plant canopy reflection models derived from the radiation transfer equation

    NASA Technical Reports Server (NTRS)

    Beeth, D. R.

    1975-01-01

    A collection of bidirectional canopy reflection models was obtained from the solution of the radiation transfer equation for a horizontally homogeneous canopy. A phase function is derived for a collection of bidirectionally reflecting and transmitting planar elements characterized geometrically by slope and azimuth density functions. Two approaches to solving the radiation transfer equation for the canopy are presented. One approach factors the radiation transfer equation into a solvable set of three first-order linear differential equations by assuming that the radiation field within the canopy can be initially approximated by three components: uniformly diffuse downwelling, uniformly diffuse upwelling, and attenuated specular. The solution to these equations, which can be iterated to any degree of accuracy, was used to obtain overall canopy reflection from the formal solution to the radiation transfer equation. A programable solution to canopy overall bidirectional reflection is given for this approach. The special example of Lambertian leaves with constant leaf bidirectional reflection and scattering functions is considered, and a programmable solution for this example is given. The other approach to solving the radiation transfer equation, a generalized Chandrasekhar technique, is presented in the appendix.

  9. Adjuvant Bidirectional Chemotherapy Using an Intraperitoneal Port

    PubMed Central

    Sugarbaker, Paul H.; Bijelic, Lana

    2012-01-01

    Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been established as treatment options for patients with peritoneal metastases or peritoneal mesothelioma. However, this novel treatment strategy remains associated with a large percentage of local-regional treatment failures. These treatment failures are attributed to the inadequacy of HIPEC to maintain a surgical complete response. Management strategies to supplement CRS and HIPEC are indicated. A simplified approach to the intraoperative placement of an intraperitoneal port for adjuvant bidirectional chemotherapy (ABC) was devised. Four different chemotherapy treatment plans were utilized depending upon the primary site of the malignancy. Thirty-one consecutive patients with an intraoperative placement of the intraperitoneal port were available for study. The incidence of adverse events that caused an early discontinuation of the bidirectional chemotherapy occurred in 75% of the 8 patients who had an incomplete cytoreduction and in 0% of patients who had a complete cytoreduction. All of the patients who had complete cytoreduction completed at least 5 of the scheduled 6 bidirectional chemotherapy treatments. Adjuvant bidirectional chemotherapy is possible following a major cytoreductive surgical procedure using a simplified method of intraoperative intraperitoneal port placement. PMID:22888340

  10. Bidirectional reflection functions from surface bump maps

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cabral, B.; Max, N.; Springmeyer, R.

    1987-04-29

    The Torrance-Sparrow model for calculating bidirectional reflection functions contains a geometrical attenuation factor to account for shadowing and occlusions in a hypothetical distribution of grooves on a rough surface. Using an efficient table-based method for determining the shadows and occlusions, we calculate the geometric attenuation factor for surfaces defined by a specific table of bump heights. Diffuse and glossy specular reflection of the environment can be handled in a unified manner by using an integral of the bidirectional reflection function times the environmental illumination, over the hemisphere of solid angle above a surface. We present a method of estimating themore » integral, by expanding the bidirectional reflection coefficient in spherical harmonics, and show how the coefficients in this expansion can be determined efficiently by reorganizing our geometric attenuation calculation.« less

  11. Firewall Traversal for CORBA Applications Using an Implementation of Bidirectional IIOP in MICO

    NASA Technical Reports Server (NTRS)

    Griffin, Robert I.; Lopez, Isaac (Technical Monitor)

    2002-01-01

    The Object Management Group (OMG) has added specifications to the General Inter-ORB Protocol (GIOP 1.2), specifically the Internet Inter-ORB Protocol (IIOP 1.2), that allow servers and clients on opposing sides of a firewall to reverse roles and still communicate freely. This addition to the GIOP specifications is referred to as Bidirectional GIOP. The implementation of these specifications as applied to communication over TCP/IP connections is referred to as 'Bidirectional Internet Inter-ORB Protocol' or BiDirIIOP. This paper details the implementation and testing of the BiDirIIOP Specification in an open source ORB, MICO, that did not previously support Bidirectional GIOP. It also provides simple contextual information and a description of the OMG GIOP/IIOP messaging protocols.

  12. Probabilistic resumable bidirectional quantum teleportation

    NASA Astrophysics Data System (ADS)

    Gou, Yi-Tao; Shi, Hai-Long; Wang, Xiao-Hui; Liu, Si-Yuan

    2017-11-01

    In order to effectively use partially entangled pairs, we consider two kinds of generalized bidirectional quantum teleportation (GBQT) protocols in the different cases: (I) Alice and Bob send messages to each other, and (II) Bob replays Alice after he received Alice's message, where partially entangled pairs are utilized as the quantum channels. However, the states to be teleported will be destroyed if GBQT fails. To solve this problem, we show an improved project, probabilistic resumable bidirectional quantum teleportation (RBQT), where the states to be teleported can be rebuilt exactly by senders when RBQT has not been successfully achieved. Thus, we are able to carry out RBQT many times until it succeeds, although there are no other copies of the initial states. In RBQT, weak entanglement can also be utilized to bidirectionally teleport unknown states successfully.

  13. Patterns of intimate partner violence and associated risk factors among married enlisted female soldiers.

    PubMed

    Forgey, Mary Ann; Badger, Lee

    2010-01-01

    A sample of 248 enlisted active duty females married to civilian spouses completed a self-report survey that asked about their own and their spouse's violence. The survey also asked about their sex-role attitudes, marital satisfaction, alcohol use, childhood trauma, and depression. Results identified patterns of intimate partner violence and their relationship to the psychosocial risk factors. Females experiencing severe bidirectional violence were likely to be the most depressed and to have a history of child sexual abuse. Females experiencing minor bidirectional violence did not share any of the psychosocial risk factors found for severe bidirectional violence. Females perpetrating unilateral violence toward their spouses were found to be as satisfied in their marriages as nonviolent couples and less depressed than the females experiencing bidirectional violence.

  14. Isomer-Specific Hydrogen Bonding as a Design Principle for Bidirectionally Quantitative and Redshifted Hemithioindigo Photoswitches.

    PubMed

    Zweig, Joshua E; Newhouse, Timothy R

    2017-08-16

    A new class of bidirectionally quantitative photoswitches based on the hemithioindigo (HTI) scaffold is reported. Incorporation of a pyrrole hydrogen-bond donor leads to a bathochromic shift allowing for quantitative bidirectional isomerization. Additionally, extending conjugation from the electron-rich pyrrole results in quantitative visible-light photoswitches, as well as photoswitches that isomerize with red and near-infrared light. The presence of the hydrogen bond leading to the observed redshift is supported by computational and spectroscopic evidence.

  15. Advanced medium-voltage bidirectional dc-dc conversion systems for future electric energy delivery and management systems

    NASA Astrophysics Data System (ADS)

    Fan, Haifeng

    2011-12-01

    The distributed renewable energy generation and utilization are constantly growing, and are expected to be integrated with the conventional grid. The growing pressure for innovative solutions will demand power electronics to take an even larger role in future electric energy delivery and management systems, since power electronics are required for the conversion and control of electric energy by most dispersed generation systems Furthermore, power electronics systems can provide additional intelligent energy management, grid stability and power quality capabilities. Medium-voltage isolated dc-dc converter will become one of the key interfaces for grid components with moderate power ratings. To address the demand of medium voltage (MV) and high power capability for future electric energy delivery and management systems, the power electronics community and industry have been reacting in two different ways: developing semiconductor technology or directly connecting devices in series/parallel to reach higher nominal voltages and currents while maintaining conventional converter topologies; and by developing new converter topologies with traditional semiconductor technology, known as multilevel converters or modular converters. The modular approach uses the well-known, mature, and cheaper power semiconductor devices by adopting new converter topologies. The main advantages of the modular approach include: significant improvement in reliability by introducing desired level of redundancy; standardization of components leading to reduction in manufacturing cost and time; power systems can be easily reconfigured to support varying input-output specifications; and possibly higher efficiency and power density of the overall system. Input-series output-parallel (ISOP) modular configuration is a good choice to realize MV to low voltage (LV) conversion for utility application. However, challenges still remain. First of all, for the high-frequency MV utility application, the low switching loss and conduction loss are must-haves for high efficiency, while bidirectional power flow capability is a must for power management requirement. To address the demand, the phase-shift dual-halfbridge (DHB) is proposed as the constituent module of ISOP configuration for MV application. The proposed ISOP DHB converter employs zero-voltage-switching (ZVS) technique combined with LV MOSFETs to achieve low switching and conduction losses under high frequency operation, and therefore high efficiency and high power density, and bidirectional power flow as well. Secondly, a large load range of high efficiency is desired rather than only a specific load point due to the continuous operation and large load variation range of utility application, which is of high importance because of the rising energy cost. This work proposes a novel DHB converter with an adaptive commutation inductor. By utilizing an adaptive inductor as the main energy transfer element, the output power can be controlled by not only the phase shift but also the commutation inductance, which allows the circulating energy to be optimized for different load conditions to maintain ZVS under light load conditions and minimize additional conduction losses under heavy load conditions as well. As a result, the efficiency at both light and heavy load can be significantly improved compared with the conventional DHB converter, and therefore extended high-efficiency range can be achieved. In addition, current stress of switch devices can be reduced. The theoretical analysis is presented and validated by the experimental results on a 50 kHz, 1 kW dc-dc converter module. Thirdly, input-voltage sharing and output-current sharing are critical to assure the advantages of the ISOP modular configuration. To solve this issue, an identically distributed control scheme is proposed in this work. The proposed control scheme, using only one distributed voltage loop to realize both input-voltage and output-current sharing, provides plug-and-play capability, possible high-level fault tolerance, and easy implementation. Another unique advantage of the proposed ISOP DHB converter is the power rating can be easily extended further by directly connecting multiple ISOP DHB converters in input-parallel-outparallel (IPOP) while no additional control is needed. The proposed control scheme is elaborated using the large-signal average model. Further, the stability of the control schemes is analyzed in terms of the constituent modules' topology as well as the configuration, and then an important fact that the stability of control scheme depends on not only the configuration but also the constituent module topology is first revealed in this work. Finally, the simulation and experimental results of an ISOP DHB converter consisting of three modules are presented to verify the proposed control scheme and the high frequency high efficiency operation.

  16. Blood flow patterns during incremental and steady-state aerobic exercise.

    PubMed

    Coovert, Daniel; Evans, LeVisa D; Jarrett, Steven; Lima, Carla; Lima, Natalia; Gurovich, Alvaro N

    2017-05-30

    Endothelial shear stress (ESS) is a physiological stimulus for vascular homeostasis, highly dependent on blood flow patterns. Exercise-induced ESS might be beneficial on vascular health. However, it is unclear what type of ESS aerobic exercise (AX) produces. The aims of this study are to characterize exercise-induced blood flow patterns during incremental and steady-state AX. We expect blood flow pattern during exercise will be intensity-dependent and bidirectional. Six college-aged students (2 males and 4 females) were recruited to perform 2 exercise tests on cycleergometer. First, an 8-12-min incremental test (Test 1) where oxygen uptake (VO2), heart rate (HR), blood pressure (BP), and blood lactate (La) were measured at rest and after each 2-min step. Then, at least 48-hr. after the first test, a 3-step steady state exercise test (Test 2) was performed measuring VO2, HR, BP, and La. The three steps were performed at the following exercise intensities according to La: 0-2 mmol/L, 2-4 mmol/L, and 4-6 mmol/L. During both tests, blood flow patterns were determined by high-definition ultrasound and Doppler on the brachial artery. These measurements allowed to determine blood flow velocities and directions during exercise. On Test 1 VO2, HR, BP, La, and antegrade blood flow velocity significantly increased in an intensity-dependent manner (repeated measures ANOVA, p<0.05). Retrograde blood flow velocity did not significantly change during Test 1. On Test 2 all the previous variables significantly increased in an intensity-dependent manner (repeated measures ANOVA, p<0.05). These results support the hypothesis that exercise induced ESS might be increased in an intensity-dependent way and blood flow patterns during incremental and steady-state exercises include both antegrade and retrograde blood flows.

  17. Mefenamic acid bi-directionally modulates the transient outward K{sup +} current in rat cerebellar granule cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang Man; Shi Wenjie; Fei Xiaowei

    2008-02-01

    The effect of non-steroidal anti-inflammatory drugs (NSAIDs) on ion channels has been widely studied in several cell models, but less is known about their modulatory mechanisms. In this report, the effect of mefenamic acid on voltage-activated transient outward K{sup +} current (I{sub A}) in cultured rat cerebellar granule cells was investigated. At a concentration of 5 {mu}M to 100 {mu}M, mefenamic acid reversibly inhibited I{sub A} in a dose-dependent manner. However, mefenamic acid at a concentration of 1 {mu}M significantly increased the amplitude of I{sub A} to 113 {+-} 1.5% of the control. At more than 10 {mu}M, mefenamic acidmore » inhibited the amplitude of I{sub A} without any effect on activation or inactivation. In addition, a higher concentration of mefenamic acid induced a significant acceleration of recovery from inactivation with an increase of the peak amplitude elicited by the second test pulse. Intracellular application of mefenamic acid could significantly increase the amplitude of I{sub A}, but had no effect on the inhibition induced by extracellular mefenamic acid, implying that mefenamic acid may exert its effect from both inside and outside the ion channel. Furthermore, the activation of current induced by intracellular application of mefenamic acid was mimicked by other cyclooxygenase inhibitors and arachidonic acid. Our data demonstrate that mefenamic acid is able to bi-directionally modulate I{sub A} channels in neurons at different concentrations and by different methods of application, and two different mechanisms may be involved.« less

  18. State-Dependent Decoding Algorithms Improve the Performance of a Bidirectional BMI in Anesthetized Rats.

    PubMed

    De Feo, Vito; Boi, Fabio; Safaai, Houman; Onken, Arno; Panzeri, Stefano; Vato, Alessandro

    2017-01-01

    Brain-machine interfaces (BMIs) promise to improve the quality of life of patients suffering from sensory and motor disabilities by creating a direct communication channel between the brain and the external world. Yet, their performance is currently limited by the relatively small amount of information that can be decoded from neural activity recorded form the brain. We have recently proposed that such decoding performance may be improved when using state-dependent decoding algorithms that predict and discount the large component of the trial-to-trial variability of neural activity which is due to the dependence of neural responses on the network's current internal state. Here we tested this idea by using a bidirectional BMI to investigate the gain in performance arising from using a state-dependent decoding algorithm. This BMI, implemented in anesthetized rats, controlled the movement of a dynamical system using neural activity decoded from motor cortex and fed back to the brain the dynamical system's position by electrically microstimulating somatosensory cortex. We found that using state-dependent algorithms that tracked the dynamics of ongoing activity led to an increase in the amount of information extracted form neural activity by 22%, with a consequently increase in all of the indices measuring the BMI's performance in controlling the dynamical system. This suggests that state-dependent decoding algorithms may be used to enhance BMIs at moderate computational cost.

  19. Modelling bidirectional fluxes of methanol and acetaldehyde with the FORCAsT canopy exchange model

    DOE PAGES

    Ashworth, Kirsti; Chung, Serena H.; McKinney, Karena A.; ...

    2016-12-15

    Here, the FORCAsT canopy exchange model was used to investigate the underlying mechanisms governing foliage emissions of methanol and acetaldehyde, two short chain oxygenated volatile organic compounds ubiquitous in the troposphere and known to have strong biogenic sources, at a northern mid-latitude forest site. The explicit representation of the vegetation canopy within the model allowed us to test the hypothesis that stomatal conductance regulates emissions of these compounds to an extent that its influence is observable at the ecosystem scale, a process not currently considered in regional- or global-scale atmospheric chemistry models. Here, we found that FORCAsT could only reproducemore » the magnitude and diurnal profiles of methanol and acetaldehyde fluxes measured at the top of the forest canopy at Harvard Forest if light-dependent emissions were introduced to the model. With the inclusion of such emissions, FORCAsT was able to successfully simulate the observed bidirectional exchange of methanol and acetaldehyde. Although we found evidence that stomatal conductance influences methanol fluxes and concentrations at scales beyond the leaf level, particularly at dawn and dusk, we were able to adequately capture ecosystem exchange without the addition of stomatal control to the standard parameterisations of foliage emissions, suggesting that ecosystem fluxes can be well enough represented by the emissions models currently used.« less

  20. Longitudinal Associations Among Relationship Satisfaction, Sexual Satisfaction, and Frequency of Sex in Early Marriage.

    PubMed

    McNulty, James K; Wenner, Carolyn A; Fisher, Terri D

    2016-01-01

    The current research used two 8-wave longitudinal studies spanning the first 4-5 years of 207 marriages to examine the potential bidirectional associations among marital satisfaction, sexual satisfaction, and frequency of sex. All three variables declined over time, though the rate of decline in each variable became increasingly less steep. Controlling for these changes, own marital and sexual satisfaction were bidirectionally positively associated with one another; higher levels of marital satisfaction at one wave of assessment predicted more positive changes in sexual satisfaction from that assessment to the next and higher levels of sexual satisfaction at one wave of assessment predicted more positive changes in marital satisfaction from that assessment to the next. Likewise, own sexual satisfaction and frequency of sex were bidirectionally positively associated with one another. Additionally, partner sexual satisfaction positively predicted changes in frequency of sex and own sexual satisfaction among husbands, yet partner marital satisfaction negatively predicted changes in both frequency of sex and own sexual satisfaction. Controlling these associations, marital satisfaction did not directly predict changes in frequency of sex or vice versa. Only the association between partner sexual satisfaction and changes in own sexual satisfaction varied across men and women and none of the key effects varied across the studies. These findings suggest that sexual and relationship satisfaction are intricately intertwined and thus that interventions to treat and prevent marital distress may benefit by targeting the sexual relationship and interventions to treat and prevent sexual distress in marriage may benefit by targeting the marital relationship.

  1. Longitudinal Associations among Relationship Satisfaction, Sexual Satisfaction, and Frequency of Sex in Early Marriage

    PubMed Central

    McNulty, James K.; Wenner, Carolyn A.; Fisher, Terri D.

    2014-01-01

    The current research used two 8-wave longitudinal studies spanning the first 4–5 years of 207 marriages to examine the potential bidirectional associations among marital satisfaction, sexual satisfaction, and frequency of sex. All three variables declined over time, though the rate of decline in each variable became increasingly less steep. Controlling for these changes, own marital and sexual satisfaction were bidirectionally positively associated with one another; higher levels of marital satisfaction at one wave of assessment predicted more positive changes in sexual satisfaction from that assessment to the next and higher levels of sexual satisfaction at one wave of assessment predicted more positive changes in marital satisfaction from that assessment to the next. Likewise, own sexual satisfaction and frequency of sex were bidirectionally positively associated with one another. Additionally, partner sexual satisfaction positively predicted changes in frequency of sex and own sexual satisfaction among husbands, yet partner marital satisfaction negatively predicted changes in both frequency of sex and own sexual satisfaction. Controlling these associations, marital satisfaction did not directly predict changes in frequency of sex or vice versa. Only the association between partner sexual satisfaction and changes in own sexual satisfaction varied across men and women and none of the key effects varied across the studies. These findings suggest that sexual and relationship satisfaction are intricately intertwined and thus that interventions to treat and prevent marital distress may benefit by targeting the sexual relationship and interventions to treat and prevent sexual distress in marriage may benefit by targeting the marital relationship. PMID:25518817

  2. Neuroengineering tools/applications for bidirectional interfaces, brain-computer interfaces, and neuroprosthetic implants - a review of recent progress.

    PubMed

    Rothschild, Ryan Mark

    2010-01-01

    The main focus of this review is to provide a holistic amalgamated overview of the most recent human in vivo techniques for implementing brain-computer interfaces (BCIs), bidirectional interfaces, and neuroprosthetics. Neuroengineering is providing new methods for tackling current difficulties; however neuroprosthetics have been studied for decades. Recent progresses are permitting the design of better systems with higher accuracies, repeatability, and system robustness. Bidirectional interfaces integrate recording and the relaying of information from and to the brain for the development of BCIs. The concepts of non-invasive and invasive recording of brain activity are introduced. This includes classical and innovative techniques like electroencephalography and near-infrared spectroscopy. Then the problem of gliosis and solutions for (semi-) permanent implant biocompatibility such as innovative implant coatings, materials, and shapes are discussed. Implant power and the transmission of their data through implanted pulse generators and wireless telemetry are taken into account. How sensation can be relayed back to the brain to increase integration of the neuroengineered systems with the body by methods such as micro-stimulation and transcranial magnetic stimulation are then addressed. The neuroprosthetic section discusses some of the various types and how they operate. Visual prosthetics are discussed and the three types, dependant on implant location, are examined. Auditory prosthetics, being cochlear or cortical, are then addressed. Replacement hand and limb prosthetics are then considered. These are followed by sections concentrating on the control of wheelchairs, computers and robotics directly from brain activity as recorded by non-invasive and invasive techniques.

  3. Neuroengineering Tools/Applications for Bidirectional Interfaces, Brain–Computer Interfaces, and Neuroprosthetic Implants – A Review of Recent Progress

    PubMed Central

    Rothschild, Ryan Mark

    2010-01-01

    The main focus of this review is to provide a holistic amalgamated overview of the most recent human in vivo techniques for implementing brain–computer interfaces (BCIs), bidirectional interfaces, and neuroprosthetics. Neuroengineering is providing new methods for tackling current difficulties; however neuroprosthetics have been studied for decades. Recent progresses are permitting the design of better systems with higher accuracies, repeatability, and system robustness. Bidirectional interfaces integrate recording and the relaying of information from and to the brain for the development of BCIs. The concepts of non-invasive and invasive recording of brain activity are introduced. This includes classical and innovative techniques like electroencephalography and near-infrared spectroscopy. Then the problem of gliosis and solutions for (semi-) permanent implant biocompatibility such as innovative implant coatings, materials, and shapes are discussed. Implant power and the transmission of their data through implanted pulse generators and wireless telemetry are taken into account. How sensation can be relayed back to the brain to increase integration of the neuroengineered systems with the body by methods such as micro-stimulation and transcranial magnetic stimulation are then addressed. The neuroprosthetic section discusses some of the various types and how they operate. Visual prosthetics are discussed and the three types, dependant on implant location, are examined. Auditory prosthetics, being cochlear or cortical, are then addressed. Replacement hand and limb prosthetics are then considered. These are followed by sections concentrating on the control of wheelchairs, computers and robotics directly from brain activity as recorded by non-invasive and invasive techniques. PMID:21060801

  4. The role of the bidirectional hydrogenase in cyanobacteria.

    PubMed

    Carrieri, Damian; Wawrousek, Karen; Eckert, Carrie; Yu, Jianping; Maness, Pin-Ching

    2011-09-01

    Cyanobacteria have tremendous potential to produce clean, renewable fuel in the form of hydrogen gas derived from solar energy and water. Of the two cyanobacterial enzymes capable of evolving hydrogen gas (nitrogenase and the bidirectional hydrogenase), the hox-encoded bidirectional Ni-Fe hydrogenase has a high theoretical potential. The physiological role of this hydrogenase is a highly debated topic and is poorly understood relative to that of the nitrogenase. Here the structure, assembly, and expression of this enzyme, as well as its probable roles in metabolism, are discussed and analyzed to gain perspective on its physiological role. It is concluded that the bidirectional hydrogenase in cyanobacteria primarily functions as a redox regulator for maintaining a proper oxidation/reduction state in the cell. Recommendations for future research to test this hypothesis are discussed. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. A reference standard for bidirectional reflection distribution function and bidirectional transmission distribution function measurement

    NASA Technical Reports Server (NTRS)

    Witherow, William K. (Inventor)

    1988-01-01

    A Lambertian reference standard for uniformly scattering a beam of light is constructed of a plate having a planar surface with a layer of glue disposed on the surface. An evenly packed layer of monodisperse spheres is set in the layer, and when the standard is used for bi-directional (BRDF) measurements, the spheres are coated with a layer of highly relective substance, such as gold or silver. When the standard is used for bi-directional transmittance distribution function (BTDF) measurements, the spheres are of a transparent material and are provided with a roughened surface, as by acid etching. In this case, the layer of glue is an optical cement, and the plate is of glass, with the spheres, the layer, and the plate all possessing a similar refractive index.

  6. Experimental research on the stability and the multilongitudinal mode interference of bidirectional outputs of LD-pumped solid state ring laser

    NASA Astrophysics Data System (ADS)

    Wan, Shunping; Tian, Qian; Sun, Liqun; Yao, Minyan; Mao, Xianhui; Qiu, Hongyun

    2004-05-01

    This paper reports an experimental research on the stability of bidirectional outputs and multi-longitudinal mode interference of laser diode end-pumped Nd:YVO4 solid-state ring laser (DPSSL). The bidirectional, multi-longitudinal and TEM00 mode continuous wave outputs are obtained and the output powers are measured and their stabilities are analyzed respectively. The spectral characteristic of the outputs is measured. The interfering pattern of the bidirectional longitudinal mode outputs is obtained and analyzed in the condition of the ring cavity with rotation velocity. The movement of the interfering fringe of the multi-longitudinal modes is very sensitive to the deformation of the setup base and the fluctuation of the intracavity air, but is stationary or randomly dithers when the stage is rotating.

  7. Sedimentary earthquake records in the İzmit Gulf, Sea of Marmara, Turkey

    NASA Astrophysics Data System (ADS)

    Çağatay, M. N.; Erel, L.; Bellucci, L. G.; Polonia, A.; Gasperini, L.; Eriş, K. K.; Sancar, Ü.; Biltekin, D.; Uçarkuş, G.; Ülgen, U. B.; Damcı, E.

    2012-12-01

    Sedimentary earthquake records of the last 2400 a, including that of the devastating 17 August 1999 İzmit earthquake (Mw = 7.4), were studied in cores from the 210 m-deep central Karamürsel Basin of the İzmit Gulf in the eastern Sea of Marmara, using laser grain-size, physical properties, stable O and C isotopes and XRF Core Scanner analyses, and dated by radionuclide and radiocarbon methods. The earthquake records are represented by turbidite-homogenite mass-flow units (THU) that commonly contain a basal coarse layer, a middle laminated silt layer and an overlying homogeneous mud layer. The coarse basal part has a sharp and sometimes scoured lower boundary, and includes multiple coarse (sand/silt) layers or laminae showing normal size grading. Multiple coarse layers and occasional bi-directional cross-bedding suggest deposition from a bed-load during water column oscillations, or seiche effect. The grain-size characteristics of the overlaying laminated silt and the homogeneous mud units indicate deposition from weak oscillating currents and homogeneous suspension, respectively. High Mn value just below the base of THUs suggests diagenetic enrichment at oxic/anoxic redox boundary before the mass-flow event. Sharp decrease in Mn with very low values within the THUs suggests transient redox conditions following the mass-flow. Variable geochemical compositions of the basal coarse layers indicate different sediment sources for different THUs. Eight sedimentary earthquake records observed in the last 2400 a in the İzmit Gulf can be confidently correlated with the historical earthquakes of 1999, 1509 AD (Ms = 7.2), 1296 AD (I = VII), 865 AD (I = VIII), 740 AD (I = VIII), 268 AD (I = VIII), 358 AD (I = IX), and 427 BC. This gives an earthquake recurrence time of ca. 300 a, with the interval between consecutive events ranging from 90 to 695 a.

  8. Survey of the Influence of the Width of Urban Branch Roads on the Meeting of Two-Way Vehicle Flows

    PubMed Central

    Chen, Qun; Zhao, Yunan; Pan, Shuangli; Wang, Yan

    2016-01-01

    Branch roads, which are densely distributed in cities, allow for the flow of local traffic and provide connections between the city and outlying areas. Branch roads are typically narrow, and two-way traffic flows on branch roads are thus affected when vehicles traveling in opposite directions meet. This study investigates the changes in the velocities of vehicles when they meet on two-way branch roads. Various widths of branch roads were selected, and their influence on traffic flows was investigated via a video survey. The results show that, depending on the average vehicle velocity, branch roads require different widths to prevent a large decrease in velocity when vehicles meet. When the velocity on a branch road is not high (e.g., the average velocity without meeting is approximately 6 m/s), appropriately increasing the road width will notably increase the meeting velocity. However, when the velocity is high (e.g., the average velocity without meeting is greater than 10 m/s), there is a large decrease in velocity when meeting even if the road surface is wide (6.5 m). This study provides a basis for selecting the width of urban branch roads and the simulation of bidirectional traffic on such roads. PMID:26881427

  9. Survey of the Influence of the Width of Urban Branch Roads on the Meeting of Two-Way Vehicle Flows.

    PubMed

    Chen, Qun; Zhao, Yunan; Pan, Shuangli; Wang, Yan

    2016-01-01

    Branch roads, which are densely distributed in cities, allow for the flow of local traffic and provide connections between the city and outlying areas. Branch roads are typically narrow, and two-way traffic flows on branch roads are thus affected when vehicles traveling in opposite directions meet. This study investigates the changes in the velocities of vehicles when they meet on two-way branch roads. Various widths of branch roads were selected, and their influence on traffic flows was investigated via a video survey. The results show that, depending on the average vehicle velocity, branch roads require different widths to prevent a large decrease in velocity when vehicles meet. When the velocity on a branch road is not high (e.g., the average velocity without meeting is approximately 6 m/s), appropriately increasing the road width will notably increase the meeting velocity. However, when the velocity is high (e.g., the average velocity without meeting is greater than 10 m/s), there is a large decrease in velocity when meeting even if the road surface is wide (6.5 m). This study provides a basis for selecting the width of urban branch roads and the simulation of bidirectional traffic on such roads.

  10. Helical localized wave solutions of the scalar wave equation.

    PubMed

    Overfelt, P L

    2001-08-01

    A right-handed helical nonorthogonal coordinate system is used to determine helical localized wave solutions of the homogeneous scalar wave equation. Introducing the characteristic variables in the helical system, i.e., u = zeta - ct and v = zeta + ct, where zeta is the coordinate along the helical axis, we can use the bidirectional traveling plane wave representation and obtain sets of elementary bidirectional helical solutions to the wave equation. Not only are these sets bidirectional, i.e., based on a product of plane waves, but they may also be broken up into right-handed and left-handed solutions. The elementary helical solutions may in turn be used to create general superpositions, both Fourier and bidirectional, from which new solutions to the wave equation may be synthesized. These new solutions, based on the helical bidirectional superposition, are members of the class of localized waves. Examples of these new solutions are a helical fundamental Gaussian focus wave mode, a helical Bessel-Gauss pulse, and a helical acoustic directed energy pulse train. Some of these solutions have the interesting feature that their shape and localization properties depend not only on the wave number governing propagation along the longitudinal axis but also on the normalized helical pitch.

  11. Nanoparticles and nonlinear thermal radiation properties in the rheology of polymeric material

    NASA Astrophysics Data System (ADS)

    Awais, M.; Hayat, T.; Muqaddass, N.; Ali, A.; Aqsa; Awan, Saeed Ehsan

    2018-03-01

    The present analysis is related to the dynamics of polymeric liquids (Oldroyd-B model) with the presence of nanoparticles. The rheological system is considered under the application of nonlinear thermal radiations. Energy and concentration equations are presented when thermophoresis and Brownian motion effects are present. Bidirectional form of stretching is considered to interpret the three-dimensional flow dynamics of polymeric liquid. Making use of the similarity transformations, problem is reduced into ordinary differential system which is approximated by using HAM. Influence of physical parameters including Deborah number, thermophoresis and Brownian motion on velocity, temperature and mass fraction expressions are plotted and analyzed. Numerical values for local Sherwood and Nusselt numbers are presented and discussed.

  12. Optical computing using optical flip-flops in Fourier processors: use in matrix multiplication and discrete linear transforms.

    PubMed

    Ando, S; Sekine, S; Mita, M; Katsuo, S

    1989-12-15

    An architecture and the algorithms for matrix multiplication using optical flip-flops (OFFs) in optical processors are proposed based on residue arithmetic. The proposed system is capable of processing all elements of matrices in parallel utilizing the information retrieving ability of optical Fourier processors. The employment of OFFs enables bidirectional data flow leading to a simpler architecture and the burden of residue-to-decimal (or residue-to-binary) conversion to operation time can be largely reduced by processing all elements in parallel. The calculated characteristics of operation time suggest a promising use of the system in a real time 2-D linear transform.

  13. MPS Solidification Model. Volume 2: Operating guide and software documentation for the unsteady model

    NASA Technical Reports Server (NTRS)

    Maples, A. L.

    1981-01-01

    The operation of solidification Model 2 is described and documentation of the software associated with the model is provided. Model 2 calculates the macrosegregation in a rectangular ingot of a binary alloy as a result of unsteady horizontal axisymmetric bidirectional solidification. The solidification program allows interactive modification of calculation parameters as well as selection of graphical and tabular output. In batch mode, parameter values are input in card image form and output consists of printed tables of solidification functions. The operational aspects of Model 2 that differ substantially from Model 1 are described. The global flow diagrams and data structures of Model 2 are included. The primary program documentation is the code itself.

  14. Bidirectional Reflectance Round-Robin in Support of the Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Early, E.; Barnes, P.; Johnson, B.; Butler, J.; Bruegge, C.; Biggar, S.; Spyak, P.; Pavlov, M.

    1999-01-01

    Laboratory measurements of the bidirectional reflectance distribution function (BRDRF) of diffuse reflectors are required to support calibration in the Earth Observing System (EOS) program of the National Aeronautics and Space Administration.

  15. The Bloomsburg University Goniometer (B.U.G.) Laboratory: An Integrated Laboratory for Measuring Bidirectional Reflectance Functions

    NASA Technical Reports Server (NTRS)

    Shepard, M. K.

    2001-01-01

    We have constructed a photometric goniometer for measuring the full bidirectional reflectance function of planetary analog materials. Additional information is contained in the original extended abstract.

  16. The Connected Steady State Model and the Interdependence of the CSF Proteome and CSF Flow Characteristics.

    PubMed

    Metzger, Fabian; Mischek, Daniel; Stoffers, Frédéric

    2017-01-01

    Here we show that the hydrodynamic radii-dependent entry of blood proteins into cerebrospinal fluid (CSF) can best be modeled with a diffusional system of consecutive interdependent steady states between barrier-restricted molecular flux and bulk flow of CSF. The connected steady state model fits precisely to experimental results and provides the theoretical backbone to calculate the in-vivo hydrodynamic radii of blood-derived proteins as well as individual barrier characteristics. As the experimental reference set we used a previously published large-scale patient cohort of CSF to serum quotient ratios of immunoglobulins in relation to the respective albumin quotients. We related the inter-individual variances of these quotient relationships to the individual CSF flow time and barrier characteristics. We claim that this new concept allows the diagnosis of inflammatory processes with Reibergrams derived from population-based thresholds to be shifted to individualized judgment, thereby improving diagnostic sensitivity. We further use the source-dependent gradient patterns of proteins in CSF as intrinsic tracers for CSF flow characteristics. We assume that the rostrocaudal gradient of blood-derived proteins is a consequence of CSF bulk flow, whereas the slope of the gradient is a consequence of the unidirectional bulk flow and bidirectional pulsatile flow of CSF. Unlike blood-derived proteins, the influence of CSF flow characteristics on brain-derived proteins in CSF has been insufficiently discussed to date. By critically reviewing existing experimental data and by reassessing their conformity to CSF flow assumptions we conclude that the biomarker potential of brain-derived proteins in CSF can be improved by considering individual subproteomic dynamics of the CSF system.

  17. Tracheostomy Tube Type and Inner Cannula Selection Impact Pressure and Resistance to Air Flow.

    PubMed

    Pryor, Lee N; Baldwin, Claire E; Ward, Elizabeth C; Cornwell, Petrea L; O'Connor, Stephanie N; Chapman, Marianne J; Bersten, Andrew D

    2016-05-01

    Advancements in tracheostomy tube design now provide clinicians with a range of options to facilitate communication for individuals receiving ventilator assistance through a cuffed tube. Little is known about the impact of these modern design features on resistance to air flow. We undertook a bench model test to measure pressure-flow characteristics and resistance of a range of tubes of similar outer diameter, including those enabling subglottic suction and speech. A constant inspiratory ± expiratory air flow was generated at increasing flows up to 150 L/min through each tube (with or without optional, mandatory, or interchangeable inner cannula). Driving pressures were measured, and resistance was calculated (cm H2O/L/s). Pressures changed with increasing flow (P < .001) and tube type (P < .001), with differing patterns of pressure change according to the type of tube (P < .001) and direction of air flow. The single-lumen reference tube encountered the lowest inspiratory and expiratory pressures compared with all double-lumen tubes (P < .001); placement of an optional inner cannula increased bidirectional tube resistance by a factor of 3. For a tube with interchangeable inner cannulas, the type of cannula altered pressure and resistance differently (P < .001); the speech cannula in particular amplified pressure-flow changes and increased tube resistance by more than a factor of 4. Tracheostomy tube type and inner cannula selection imposed differing pressures and resistance to air flow during inspiration and expiration. These differences may be important when selecting airway equipment or when setting parameters for monitoring, particularly for patients receiving supported ventilation or during the weaning process. Copyright © 2016 by Daedalus Enterprises.

  18. [The case-case-time-control study design].

    PubMed

    Wang, Jing; Zhuo, Lin; Zhan, Siyan

    2014-12-01

    Although the 'self-matched case-only studies' (such as the case-cross-over or self-controlled case-series method) can control the time-invariant confounders (measured or unmeasured) through design of the study, however, they can not control those confounders that vary with time. A bidirectional case-crossover design can be used to adjust the exposure-time trends. In the areas of pharmaco-epidemiology, illness often influence the future use of medications, making a bidirectional study design problematic. Suissa's case-time-control design combines the case-crossover and the case-control design which could adjust for exposure-trend bias, but the control group may reintroduce selection bias, if the matching does not go well. We propose a "case-case-time-control" design which is an extension of the case-time-control design. However, rather than using a sample of external controls, we choose those future cases as controls for current cases to counter the bias that arising from temporal trends caused by exposure to the target of interest. In the end of this article we will discuss the strength and limitations of this design based on an applied example.

  19. Bifurcation Analysis of a DC-DC Bidirectional Power Converter Operating with Constant Power Loads

    NASA Astrophysics Data System (ADS)

    Cristiano, Rony; Pagano, Daniel J.; Benadero, Luis; Ponce, Enrique

    Direct current (DC) microgrids (MGs) are an emergent option to satisfy new demands for power quality and integration of renewable resources in electrical distribution systems. This work addresses the large-signal stability analysis of a DC-DC bidirectional converter (DBC) connected to a storage device in an islanding MG. This converter is responsible for controlling the balance of power (load demand and generation) under constant power loads (CPLs). In order to control the DC bus voltage through a DBC, we propose a robust sliding mode control (SMC) based on a washout filter. Dynamical systems techniques are exploited to assess the quality of this switching control strategy. In this sense, a bifurcation analysis is performed to study the nonlinear stability of a reduced model of this system. The appearance of different bifurcations when load parameters and control gains are changed is studied in detail. In the specific case of Teixeira Singularity (TS) bifurcation, some experimental results are provided, confirming the mathematical predictions. Both a deeper insight in the dynamic behavior of the controlled system and valuable design criteria are obtained.

  20. A Wireless 32-Channel Implantable Bidirectional Brain Machine Interface

    PubMed Central

    Su, Yi; Routhu, Sudhamayee; Moon, Kee S.; Lee, Sung Q.; Youm, WooSub; Ozturk, Yusuf

    2016-01-01

    All neural information systems (NIS) rely on sensing neural activity to supply commands and control signals for computers, machines and a variety of prosthetic devices. Invasive systems achieve a high signal-to-noise ratio (SNR) by eliminating the volume conduction problems caused by tissue and bone. An implantable brain machine interface (BMI) using intracortical electrodes provides excellent detection of a broad range of frequency oscillatory activities through the placement of a sensor in direct contact with cortex. This paper introduces a compact-sized implantable wireless 32-channel bidirectional brain machine interface (BBMI) to be used with freely-moving primates. The system is designed to monitor brain sensorimotor rhythms and present current stimuli with a configurable duration, frequency and amplitude in real time to the brain based on the brain activity report. The battery is charged via a novel ultrasonic wireless power delivery module developed for efficient delivery of power into a deeply-implanted system. The system was successfully tested through bench tests and in vivo tests on a behaving primate to record the local field potential (LFP) oscillation and stimulate the target area at the same time. PMID:27669264

  1. Associations between Prosocial and Problem Behavior from Early to Late Adolescence.

    PubMed

    Padilla-Walker, Laura M; Memmott-Elison, Madison K; Coyne, Sarah M

    2018-05-01

    Though recent research has highlighted prosocial behavior as negatively associated with problem behavior during adolescence, we know little about how these variables might be associated longitudinally, whether there are bidirectional effects, and whether there might be different patterns of co-occurrence of behaviors for different individuals. Thus, the current study examined relations between prosocial and problem behaviors in three different ways in an attempt to better understand these associations. Participants included 500 adolescents recruited from a Northwestern state in the USA who took part in the study every year from age 12 to 18 (50% female, 67% European American). Growth curve analyses suggested that change in prosocial behavior was negatively associated with change in aggression and delinquency over time. A longitudinal panel model suggested that prosocial behavior and aggression were negatively associated bidirectionally, and that prosocial behavior was negatively associated with delinquency over time. Finally, mixture modeling conducted at ages 12, 15, and 18 revealed heterogeneity in the ways in which prosocial and problem behaviors co-occur. The discussion focuses on the complexity of interrelations between prosocial behavior and problem behavior across adolescence.

  2. Synthesis and Analysis of Custom Bi-directional Reflectivity Distribution Functions in DIRSIG

    NASA Astrophysics Data System (ADS)

    Dank, J.; Allen, D.

    2016-09-01

    The bi-directional reflectivity distribution (BRDF) function is a fundamental optical property of materials, characterizing important properties of light scattered by a surface. For accurate radiance calculations using synthetic targets and numerical simulations such as the Digital Imaging and Remote Sensing Image Generation (DIRSIG) model, fidelity of the target BRDFs is critical. While fits to measured BRDF data can be used in DIRSIG, obtaining high-quality data over a large spectral continuum can be time-consuming and expensive, requiring significant investment in illumination sources, sensors, and other specialized hardware. As a consequence, numerous parametric BRDF models are available to approximate actual behavior; but these all have shortcomings. Further, DIRSIG doesn't allow direct visualization of BRDFs, making it difficult for the user to understand the numerical impact of various models. Here, we discuss the innovative use of "mixture maps" to synthesize custom BRDFs as linear combinations of parametric models and measured data. We also show how DIRSIG's interactive mode can be used to visualize and analyze both available parametric models currently used in DIRSIG and custom BRDFs developed using our methods.

  3. Bidirectional modulation of fear extinction by mediodorsal thalamic firing in mice.

    PubMed

    Lee, Sukchan; Ahmed, Touqeer; Lee, Soojung; Kim, Huisu; Choi, Sukwoo; Kim, Duk-Soo; Kim, Sang Jeong; Cho, Jeiwon; Shin, Hee-Sup

    2011-12-25

    The mediodorsal thalamic nucleus has been implicated in the control of memory processes. However, the underlying neural mechanism remains unclear. Here we provide evidence for bidirectional modulation of fear extinction by the mediodorsal thalamic nucleus. Mice with a knockout or mediodorsal thalamic nucleus-specific knockdown of phospholipase C β4 exhibited impaired fear extinction. Mutant mediodorsal thalamic nucleus neurons in slices showed enhanced burst firing accompanied by increased T-type Ca(2+) currents; blocking of T channels in vivo rescued the fear extinction. Tetrode recordings in freely moving mice revealed that, during extinction, the single-spike (tonic) frequency of mediodorsal thalamic nucleus neurons increased in wild-type mice, but was static in mutant mice. Furthermore, tonic-evoking microstimulations of the mediodorsal thalamic nucleus, contemporaneous with the extinction tones, rescued fear extinction in mutant mice and facilitated it in wild-type mice. In contrast, burst-evoking microstimulation suppressed extinction in wild-type mice, mimicking the mutation. These results suggest that the firing mode of the mediodorsal thalamic nucleus is critical for the modulation of fear extinction.

  4. A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.

    PubMed

    Bečanović, Kristina; Nørremølle, Anne; Neal, Scott J; Kay, Chris; Collins, Jennifer A; Arenillas, David; Lilja, Tobias; Gaudenzi, Giulia; Manoharan, Shiana; Doty, Crystal N; Beck, Jessalyn; Lahiri, Nayana; Portales-Casamar, Elodie; Warby, Simon C; Connolly, Colúm; De Souza, Rebecca A G; Tabrizi, Sarah J; Hermanson, Ola; Langbehn, Douglas R; Hayden, Michael R; Wasserman, Wyeth W; Leavitt, Blair R

    2015-06-01

    Cis-regulatory variants that alter gene expression can modify disease expressivity, but none have previously been identified in Huntington disease (HD). Here we provide in vivo evidence in HD patients that cis-regulatory variants in the HTT promoter are bidirectional modifiers of HD age of onset. HTT promoter analysis identified a NF-κB binding site that regulates HTT promoter transcriptional activity. A non-coding SNP, rs13102260:G > A, in this binding site impaired NF-κB binding and reduced HTT transcriptional activity and HTT protein expression. The presence of the rs13102260 minor (A) variant on the HD disease allele was associated with delayed age of onset in familial cases, whereas the presence of the rs13102260 (A) variant on the wild-type HTT allele was associated with earlier age of onset in HD patients in an extreme case-based cohort. Our findings suggest a previously unknown mechanism linking allele-specific effects of rs13102260 on HTT expression to HD age of onset and have implications for HTT silencing treatments that are currently in development.

  5. Implantable neurotechnologies: bidirectional neural interfaces--applications and VLSI circuit implementations.

    PubMed

    Greenwald, Elliot; Masters, Matthew R; Thakor, Nitish V

    2016-01-01

    A bidirectional neural interface is a device that transfers information into and out of the nervous system. This class of devices has potential to improve treatment and therapy in several patient populations. Progress in very large-scale integration has advanced the design of complex integrated circuits. System-on-chip devices are capable of recording neural electrical activity and altering natural activity with electrical stimulation. Often, these devices include wireless powering and telemetry functions. This review presents the state of the art of bidirectional circuits as applied to neuroprosthetic, neurorepair, and neurotherapeutic systems.

  6. Industrial application of low voltage bidirectional automatic release of reserve

    NASA Astrophysics Data System (ADS)

    Popa, G. N.; Diniş, C. M.; Iagăr, A.; Deaconu, S. I.; Popa, I.

    2018-01-01

    The paper presents an analysis on low voltage industrial electrical installation controlled by bidirectional automatic release of reserve. Industrial electrical installation is for removing smoke in case of fire from a textile company. The main parts of the installation of removing smoke in case of fire are: general electrical panel; reserve electrical panel; three-phase induction motors for driven fans; electrical actuators for inlet and outlet valves; clean air inlet pipe, respectively, the outlet pipe for smoke. The operation and checking of bidirectional automatic release of reserve are present in the paper.

  7. Surface albedo from bidirectional reflectance

    NASA Technical Reports Server (NTRS)

    Ranson, K. J.; Irons, J. R.; Daughtry, C. S. T.

    1991-01-01

    The validity of integrating over discrete wavelength bands is examined to estimate total shortwave bidirectional reflectance of vegetated and bare soil surfaces. Methods for estimating albedo from multiple angle, discrete wavelength band radiometer measurements are studied. These methods include a numerical integration technique and the integration of an empirically derived equation for bidirectional reflectance. It is concluded that shortwave albedos estimated through both techniques agree favorably with the independent pyranometer measurements. Absolute rms errors are found to be 0.5 percent or less for both grass sod and bare soil surfaces.

  8. Bidirectional Neural Interfaces

    PubMed Central

    Masters, Matthew R.; Thakor, Nitish V.

    2016-01-01

    A bidirectional neural interface is a device that transfers information into and out of the nervous system. This class of devices has potential to improve treatment and therapy in several patient populations. Progress in very-large-scale integration (VLSI) has advanced the design of complex integrated circuits. System-on-chip (SoC) devices are capable of recording neural electrical activity and altering natural activity with electrical stimulation. Often, these devices include wireless powering and telemetry functions. This review presents the state of the art of bidirectional circuits as applied to neuroprosthetic, neurorepair, and neurotherapeutic systems. PMID:26753776

  9. Leaf bidirectional reflectance and transmittance in corn and soybean

    NASA Technical Reports Server (NTRS)

    Walter-Shea, E. A.; Norman, J. M.; Blad, B. L.

    1989-01-01

    Bidirectional optical properties of leaves must be adequately characterized to develop comprehensive and reliably predictive canopy radiative-transfer models. Directional reflectance and transmittance factors of individual corn and soybean leaves were measured at source incidence angles (SIAs) 20, 45, and 70 deg and numerous view angles in the visible and NIR. Bidirectional reflectance distributions changed with increasing SIA, with forward scattering most pronounced at 70 deg. Directional-hemispherical reflectance generally increased and transmittance decreased with increased SIA. Directional-hemispherical reflectance factors were higher and transmittances were lower than the nadir-viewed reflectance component.

  10. Retinal oxygen extraction in humans

    NASA Astrophysics Data System (ADS)

    Werkmeister, René M.; Schmidl, Doreen; Aschinger, Gerold; Doblhoff-Dier, Veronika; Palkovits, Stefan; Wirth, Magdalena; Garhöfer, Gerhard; Linsenmeier, Robert A.; Leitgeb, Rainer A.; Schmetterer, Leopold

    2015-10-01

    Adequate function of the retina is dependent on proper oxygen supply. In humans, the inner retina is oxygenated via the retinal circulation. We present a method to calculate total retinal oxygen extraction based on measurement of total retinal blood flow using dual-beam bidirectional Doppler optical coherence tomography and measurement of oxygen saturation by spectrophotometry. These measurements were done on 8 healthy subjects while breathing ambient room air and 100% oxygen. Total retinal blood flow was 44.3 ± 9.0 μl/min during baseline and decreased to 18.7 ± 4.2 μl/min during 100% oxygen breathing (P < 0.001) resulting in a pronounced decrease in retinal oxygen extraction from 2.33 ± 0.51 μl(O2)/min to 0.88 ± 0.14 μl(O2)/min during breathing of 100% oxygen. The method presented in this paper may have significant potential to study oxygen metabolism in hypoxic retinal diseases such as diabetic retinopathy.

  11. Vanishing characteristic speeds and critical dispersive points in nonlinear interfacial wave problems

    NASA Astrophysics Data System (ADS)

    Ratliff, Daniel J.

    2017-11-01

    Criticality plays a central role in the study of reductions and stability of hydrodynamical systems. At critical points, it is often the case that nonlinear reductions with dispersion arise to govern solution behavior. By considering when such models become bidirectional and lose their initial dispersive properties, it will be shown that higher order dispersive models may be supported in hydrodynamical systems. Precisely, this equation is a two-way Boussinesq equation with sixth order dispersion. The case of two layered shallow water is considered to illustrate this, and it is reasoned why such an environment is natural for such a system to emerge. Further, it is demonstrated that the regions in the parameter space for nontrivial flow, which admit this reduction, are vast and in fact form a continuum. The reduced model is then numerically simulated to illustrate how the two-way and higher dispersive properties suggest more exotic families of solitary wave solutions can emerge in stratified flows.

  12. Retinal oxygen extraction in humans

    PubMed Central

    Werkmeister, René M.; Schmidl, Doreen; Aschinger, Gerold; Doblhoff-Dier, Veronika; Palkovits, Stefan; Wirth, Magdalena; Garhöfer, Gerhard; Linsenmeier, Robert A.; Leitgeb, Rainer A.; Schmetterer, Leopold

    2015-01-01

    Adequate function of the retina is dependent on proper oxygen supply. In humans, the inner retina is oxygenated via the retinal circulation. We present a method to calculate total retinal oxygen extraction based on measurement of total retinal blood flow using dual-beam bidirectional Doppler optical coherence tomography and measurement of oxygen saturation by spectrophotometry. These measurements were done on 8 healthy subjects while breathing ambient room air and 100% oxygen. Total retinal blood flow was 44.3 ± 9.0 μl/min during baseline and decreased to 18.7 ± 4.2 μl/min during 100% oxygen breathing (P < 0.001) resulting in a pronounced decrease in retinal oxygen extraction from 2.33 ± 0.51 μl(O2)/min to 0.88 ± 0.14 μl(O2)/min during breathing of 100% oxygen. The method presented in this paper may have significant potential to study oxygen metabolism in hypoxic retinal diseases such as diabetic retinopathy. PMID:26503332

  13. Wireless programmable electrochemical drug delivery micropump with fully integrated electrochemical dosing sensors.

    PubMed

    Sheybani, Roya; Cobo, Angelica; Meng, Ellis

    2015-08-01

    We present a fully integrated implantable electrolysis-based micropump with incorporated EI dosing sensors. Wireless powering and data telemetry (through amplitude and frequency modulation) were utilized to achieve variable flow control and a bi-directional data link with the sensors. Wireless infusion rate control (0.14-1.04 μL/min) and dose sensing (bolus resolution of 0.55-2 μL) were each calibrated separately with the final circuit architecture and then simultaneous wireless flow control and dose sensing were demonstrated. Recombination detection using the dosing system, as well as, effects of coil separation distance and misalignment in wireless power and data transfer were studied. A custom-made normally closed spring-loaded ball check valve was designed and incorporated at the reservoir outlet to prevent backflow of fluids as a result of the reverse pressure gradient caused by recombination of electrolysis gases. Successful delivery, infusion rate control, and dose sensing were achieved in simulated brain tissue.

  14. Surface models for coupled modelling of runoff and sewer flow in urban areas.

    PubMed

    Ettrich, N; Steiner, K; Thomas, M; Rothe, R

    2005-01-01

    Traditional methods fail for the purpose of simulating the complete flow process in urban areas as a consequence of heavy rainfall and as required by the European Standard EN-752 since the bi-directional coupling between sewer and surface is not properly handled. The new methodology, developed in the EUREKA-project RisUrSim, solves this problem by carrying out the runoff on the basis of shallow water equations solved on high-resolution surface grids. Exchange nodes between the sewer and the surface, like inlets and manholes, are located in the computational grid and water leaving the sewer in case of surcharge is further distributed on the surface. Dense topographical information is needed to build a model suitable for hydrodynamic runoff calculations; in urban areas, in addition, many line-shaped elements like houses, curbs, etc. guide the runoff of water and require polygonal input. Airborne data collection methods offer a great chance to economically gather densely sampled input data.

  15. Bidirectional slapper detonator

    DOEpatents

    McCormick, Robert N.; Boyd, Melissa D.

    1984-01-01

    The disclosure is directed to a bidirectional slapper detonator. One embodiment utilizes a single bridge circuit to detonate a pair of opposing initiating pellets. A line generator embodiment uses a plurality of bridges in electrical series to generate opposing cylindrical wavefronts.

  16. Electronic bidirectional valve circuit prevents crossover distortion and threshold effect

    NASA Technical Reports Server (NTRS)

    Kernick, A.

    1966-01-01

    Four-terminal network forms a bidirectional valve which will switch or alternate an ac signal without crossover distortion or threshold effect. In this network, an isolated control signal is sufficient for circuit turn-on.

  17. Deformed barchans under alternating flows: Flume experiments and comparison with barchan dunes within Proctor Crater, Mars

    NASA Astrophysics Data System (ADS)

    Taniguchi, Keisuke; Endo, Noritaka

    2007-10-01

    It is generally considered that barchans, isolated crescentic-shaped dunes, develop where wind is unidirectional and the available sand is insufficient to cover the entire dune field; however, Bishop [Bishop, M.A., 2001. Seasonal variation of crescentic dune morphology and morphometry, Strzelecki Simpson desert, Australia. Earth Surface Process and Landforms 26, 783 791.] observed barchans that developed in areas where winds blow seasonally in opposite directions and described a peculiar deformation feature, the “rear slipface,” that is not found in ordinary barchans. Barchans under such bidirectional flows are poorly understood, and it is necessary to study barchans that formed under many different flow conditions. We conducted flume experiments to investigate the deformation of barchans under alternating water flow, and observed new deformation features in addition to rear slipfaces. We conclude that the deformation of barchans can be categorized into four types, one of which shows morphologies similar to barchans within Proctor Crater, Mars. The deformation type depends on the strength of the reverse flow relative to the forward flow and the absolute velocity of the forward flow. Comparison of our results with barchan dunes within Proctor Crater enable us to qualitatively estimate the wind strength and direction related to dune formation on Mars. These results are in agreement with those of Fenton et al. [Fenton, L.K., Toigo, A.D., Richardson, M.I., 2005. Aeolian processes in Proctor Crater on Mars: Mesoscale modeling of dune-forming winds. Journal of Geophysical Research 110 (E6), E06005.].

  18. A Novel Scheme for Bidirectional and Hybrid Quantum Information Transmission via a Seven-Qubit State

    NASA Astrophysics Data System (ADS)

    Fang, Sheng-hui; Jiang, Min

    2018-02-01

    In this paper, we present a novel scheme for bidirectional and hybrid quantum information transmission via a seven-qubit state. We demonstrate that under the control of the supervisor two distant participants can simultaneously and deterministically exchange their states with each other no matter whether they know the states or not. In our scheme, Alice can teleport an arbitrary single-qubit state (two-qubit state) to Bob and Bob can prepare a known two-qubit state (single-qubit state) for Alice simultaneously via the control of the supervisor Charlie. Compared with previous studies for single bidirectional quantum teleportation or single bidirectional remote state preparation schemes, our protocol is a kind of hybrid approach for quantum information transmission. Furthermore, it achieves success with unit probability. Notably, since only pauli operations and two-qubit and single-qubit measurements are used in our schemes, it is flexible in physical experiments.

  19. Driver-receiver combined optical transceiver modules for bidirectional optical interconnection

    NASA Astrophysics Data System (ADS)

    Park, Hyo-Hoon; Kang, Sae-Kyoung; Kim, Do-Won; Nga, Nguyen T. H.; Hwang, Sung-Hwan; Lee, Tae-Woo

    2008-02-01

    We review a bidirectional optical link scheme for memory-interface applications. A driver-receiver combined optical transceiver (TRx) modules was demonstrated on an optical printed-circuit board (OPCB) platform. To select the bidirectional electric input/output signals, a driver-receiver combined TRx IC with a switching function was designed in 0.18-μm CMOS technology. The TRx IC was integrated with VCSEL/PD chips for optical link in the TRx module. The optical TRx module was assembled on a fiber-embedded OPCB, employing a 90°-bent fiber connector for 90° deflection of light beams between the TRx module and the OPCB. The TRx module and the 90° connector were passively assembled on the OPCB, using ferrule-type guide pins/ holes. Employing these constituent components, the bidirectional optical link between a pair of TRx modules has been successfully demonstrated up to 1.25 Gb/s on the OPCB.

  20. Mechanical analysis of non-uniform bi-directional functionally graded intelligent micro-beams using modified couple stress theory

    NASA Astrophysics Data System (ADS)

    Bakhshi Khaniki, Hossein; Rajasekaran, Sundaramoorthy

    2018-05-01

    This study develops a comprehensive investigation on mechanical behavior of non-uniform bi-directional functionally graded beam sensors in the framework of modified couple stress theory. Material variation is modelled through both length and thickness directions using power-law, sigmoid and exponential functions. Moreover, beam is assumed with linear, exponential and parabolic cross-section variation through the length using power-law and sigmoid varying functions. Using these assumptions, a general model for microbeams is presented and formulated by employing Hamilton’s principle. Governing equations are solved using a mixed finite element method with Lagrangian interpolation technique, Gaussian quadrature method and Wilson’s Lagrangian multiplier method. It is shown that by using bi-directional functionally graded materials in nonuniform microbeams, mechanical behavior of such structures could be affected noticeably and scale parameter has a significant effect in changing the rigidity of nonuniform bi-directional functionally graded beams.

  1. Bidirectional chaos communication between two outer semiconductor lasers coupled mutually with a central semiconductor laser.

    PubMed

    Li, Ping; Wu, Jia-Gui; Wu, Zheng-Mao; Lin, Xiao-Dong; Deng, Dao; Liu, Yu-Ran; Xia, Guang-Qiong

    2011-11-21

    Based on a linear chain composed of a central semiconductor laser and two outer semiconductor lasers, chaos synchronization and bidirectional communication between two outer lasers have been investigated under the case that the central laser and the two outer lasers are coupled mutually, whereas there exists no coupling between the two outer lasers. The simulation results show that high-quality and stable isochronal synchronization between the two outer lasers can be achieved, while the cross-correlation coefficients between the two outer lasers and the central laser are very low under proper operation condition. Based on the high performance chaos synchronization between the two outer lasers, message bidirectional transmissions of bit rates up to 20 Gbit/s can be realized through adopting a novel decoding scheme which is different from that based on chaos pass filtering effect. Furthermore, the security of bidirectional communication is also analyzed. © 2011 Optical Society of America

  2. Bidirectional and Asymmetric Controlled Quantum Information Transmission via Five-qubit Brown State

    NASA Astrophysics Data System (ADS)

    Fang, Sheng-hui; Jiang, Min

    2017-05-01

    We put forward a new protocol of deterministic controlled bidirectional quantum information transmission, using a five-qubit Brown state. That is to say Alice wants to teleport an arbitrary single-qubit state to Bob and Bob wants to remotely prepare a known state for Alice via the control of the supervisor Charlie. In terms of physical implementations, only a CNOT gate, one Bell-state measurement and one qubit measurement are used in our protocol. Compared with previous study for solely bidirectional quantum teleportation and solely bidirectional remote state preparation schemes, our protocol is a kind of hybrid approach of information communication which makes the quantum channel multipurpose, i.e., no matter whether the transmitted state is known or unknown, the state information can be transmitted with each other via a five-qubit Brown state under the control of the third party as a supervisor.

  3. Numerical Comparison of Nasal Aerosol Administration Systems for Efficient Nose-to-Brain Drug Delivery.

    PubMed

    Dong, Jingliang; Shang, Yidan; Inthavong, Kiao; Chan, Hak-Kim; Tu, Jiyuan

    2017-12-29

    Nose-to-brain drug administration along the olfactory and trigeminal nerve pathways offers an alternative route for the treatment of central nervous system (CNS) disorders. The characterization of particle deposition remains difficult to achieve in experiments. Alternative numerical approach is applied to identify suitable aerosol particle size with maximized inhaled doses. This study numerically compared the drug delivery efficiency in a realistic human nasal cavity between two aerosol drug administration systems targeting the olfactory region: the aerosol mask system and the breath-powered bi-directional system. Steady inhalation and exhalation flow rates were applied to both delivery systems. The discrete phase particle tracking method was employed to capture the aerosol drug transport and deposition behaviours in the nasal cavity. Both overall and regional deposition characteristics were analysed in detail. The results demonstrated the breath-powered drug delivery approach can produce superior olfactory deposition with peaking olfactory deposition fractions for diffusive 1 nm particles and inertial 10 μm. While for particles in the range of 10 nm to 2 μm, no significant olfactory deposition can be found, indicating the therapeutic agents should avoid this size range when targeting the olfactory deposition. The breath-powered bi-directional aerosol delivery approach shows better drug delivery performance globally and locally, and improved drug administration doses can be achieved in targeted olfactory region.

  4. Bidirectional reflectance correction model for coastal water and its application to minimization of uncertainties in satellite and in-situ water leaving radiances at Long Island Sound Coastal Observatory site

    NASA Astrophysics Data System (ADS)

    Hlaing, Soe Min

    Ocean Color data validation is the absolute requirement to provide the steady and reliable Ocean Color data stream. In the validation of Ocean Color data, water-leaving radiances, retrieved from in situ or satellite measurements, need to be compared in very accurate manner. Both in-situ and satellite data to be used in the comparisons are required to be the representative of the typical water and environmental condition at the site without being affected by the unexpected natural and environmental perturbation. As the result, assessments of the uncertainties in the water leaving radiance data must be carried out in the measurement and the every step of data processing procedure. With the hyper- and multi-spectral water leaving radiance data retrieved for the different viewing geometries of the instruments at the Long Island Sound Coastal Observatory (LISCO), uncertainties in the water leaving radiance data and processing procedures have been assessed and quantified. Recommendations and algorithm improvements have been also made to reduce the uncertainties in the processing and validation of Ocean Color data. Particularly, remote sensing reflectance model to correct the bidirectional angular dependencies in both in-situ and satellite data have been proposed. The proposed model is first validated with a one year time series of in situ above-water measurements acquired by collocated multi- and hyper-spectral radiometers which have different viewing geometries installed at LISCO. Match-ups and inter-comparisons performed on these concurrent measurements show that the proposed algorithm outperforms the algorithm currently in use at all wavelengths, with spectral average improvement of 2.4%. LISCO's time series data has also been used to evaluate improvements in the match-up comparisons of MODIS satellite data when the proposed Bidirectional Reflectance Distribution Function (BRDF) correction is used in lieu of the current algorithm. It has been shown that the discrepancies between coincident in-situ sea-based and satellite data were decreased by 3.15% with the use of the proposed algorithm. Possibility of the application of the developed BRDF algorithm for the open ocean conditions is also considered.

  5. 3D visualization of optical ray aberration and its broadcasting to smartphones by ray aberration generator

    NASA Astrophysics Data System (ADS)

    Hellman, Brandon; Bosset, Erica; Ender, Luke; Jafari, Naveed; McCann, Phillip; Nguyen, Chris; Summitt, Chris; Wang, Sunglin; Takashima, Yuzuru

    2017-11-01

    The ray formalism is critical to understanding light propagation, yet current pedagogy relies on inadequate 2D representations. We present a system in which real light rays are visualized through an optical system by using a collimated laser bundle of light and a fog chamber. Implementation for remote and immersive access is enabled by leveraging a commercially available 3D viewer and gesture-based remote controlling of the tool via bi-directional communication over the Internet.

  6. Design and implementation of an inexpensive target scanner for the growth of thin films by the laser-ablation process

    NASA Astrophysics Data System (ADS)

    Rao, A. M.; Moodera, J. S.

    1991-04-01

    The design of a target scanner that is inexpensive and easy to construct is described. Our target scanner system does not require an expensive personal computer to raster the laser beam uniformily over the target material, unlike the computer driven target scanners that are currently being used in the thin-film industry. The main components of our target scanner comprise a bidirectional motor, a two-position switch, and a standard optical mirror mount.

  7. Tact training versus bidirectional intraverbal training in teaching a foreign language.

    PubMed

    Dounavi, Katerina

    2014-01-01

    The current study involved an evaluation of the emergence of untrained verbal relations as a function of 3 different foreign-language teaching strategies. Two Spanish-speaking adults received foreign-language (English) tact training and native-to-foreign and foreign-to-native intraverbal training. Tact training and native-to-foreign intraverbal training resulted in the emergence of a greater number of untrained responses, and may thus be more efficient than foreign-to-native intraverbal training. © Society for the Experimental Analysis of Behavior.

  8. State of the Art Satellite and Airborne Marine Oil Spill Remote Sensing: Application to the BP Deepwater Horizon Oil Spill

    DTIC Science & Technology

    2012-01-01

    numerical oil spill model validation showing the need for improvedmodel param- eterizations of basic oil spill processes (Cheng et al., 2010). 3.1.2...2004). Modelling the bidirectional reflectance distribution function ( BRDF ) of seawater polluted by an oil film. Optics Express, 12, 1671–1676. Pilon...display a currently valid OMB control number. 1. REPORT DATE 2012 2. REPORT TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND

  9. Simulating transitional hydrodynamics of the cerebrospinal fluid at extreme scale

    NASA Astrophysics Data System (ADS)

    Jain, Kartik; Roller, Sabine; Mardal, Kent-Andre

    Chiari malformation type I is a disorder characterized by the herniation of cerebellar tonsils into the spinal canal through the foramen magnum resulting in obstruction to cerebrospinal fluid (CSF) outflow. The flow of pulsating bidirectional CSF is of acutely complex nature due to the anatomy of the conduit containing it - the subarachnoid space. We report lattice Boltzmann method based direct numerical simulations on patient specific cases with spatial resolution of 24 μm amounting meshes of up to 2 billion cells conducted on 50000 cores of the Hazelhen supercomputer in Stuttgart. The goal is to characterize intricate dynamics of the CSF at resolutions that are of the order of Kolmogorov microscales. Results unfold velocity fluctuations up to ~ 10 KHz , turbulent kinetic energy ~ 2 times of the mean flow energy in Chiari patients whereas the flow remains laminar in a control subject. The fluctuations confine near the cranio-vertebral junction and are commensurate with the extremeness of pathology and the extent of herniation. The results advocate that the manifestation of pathological conditions like Chiari malformation may lead to transitional hydrodynamics of the CSF, and a prudent calibration of numerical approach is necessary to avoid overlook of such phenomena.

  10. Therapeutic Targets for Management of Periodontitis and Diabetes

    PubMed Central

    Sima, Corneliu; Van Dyke, Thomas E.

    2016-01-01

    The increasing incidence of diabetes mellitus (DM) and chronic periodontitis (CP) worldwide imposes a rethinking of individualized therapy for patients with both conditions. Central to bidirectional links between DM and CP is deregulated systemic inflammation and dysfunctional immune responses to altered-self and non-self. Control of blood glucose levels and metabolic imbalances associated with hyperglycemia in DM, and disruption of pathogenic subgingival biofilms in CP are currently the main therapeutic approaches for these conditions. Mounting evidence suggests the need to integrate immune modulatory therapeutics in treatment regimens that address the unresolved inflammation associated with DM and CP. The current review discusses the pathogenesis of DM and CP with emphasis on deregulated inflammation, current therapeutic approaches and the novel pro-resolution lipid mediators derived from n-3 polyunsaturated fatty acids. PMID:26881443

  11. Therapeutic Targets for Management of Periodontitis and Diabetes

    PubMed Central

    Sima, Corneliu; Van Dyke, Thomas E.

    2016-01-01

    The increasing incidence of diabetes mellitus (DM) and chronic periodontitis (CP) worldwide imposes a rethinking of individualized therapy for patients with both conditions. Central to bidirectional links between DM and CP is deregulated systemic inflammation and dysfunctional immune responses to altered-self and non-self. Control of blood glucose levels and metabolic imbalances associated with hyperglycemia in DM, and disruption of pathogenic subgingival biofilms in CP are currently the main therapeutic approaches for these conditions. Mounting evidence suggests the need to integrate immune modulatory therapeutics in treatment regimens that address the unresolved inflammation associated with DM and CP. The current review discusses the pathogenesis of DM and CP with emphasis on deregulated inflammation, current therapeutic approaches and the novel pro-resolution lipid mediators derived from Ω-3 polyunsaturated fatty acids.

  12. Moving Domain Computational Fluid Dynamics to Interface with an Embryonic Model of Cardiac Morphogenesis

    PubMed Central

    Lee, Juhyun; Moghadam, Mahdi Esmaily; Kung, Ethan; Cao, Hung; Beebe, Tyler; Miller, Yury; Roman, Beth L.; Lien, Ching-Ling; Chi, Neil C.; Marsden, Alison L.; Hsiai, Tzung K.

    2013-01-01

    Peristaltic contraction of the embryonic heart tube produces time- and spatial-varying wall shear stress (WSS) and pressure gradients (∇P) across the atrioventricular (AV) canal. Zebrafish (Danio rerio) are a genetically tractable system to investigate cardiac morphogenesis. The use of Tg(fli1a:EGFP)y1 transgenic embryos allowed for delineation and two-dimensional reconstruction of the endocardium. This time-varying wall motion was then prescribed in a two-dimensional moving domain computational fluid dynamics (CFD) model, providing new insights into spatial and temporal variations in WSS and ∇P during cardiac development. The CFD simulations were validated with particle image velocimetry (PIV) across the atrioventricular (AV) canal, revealing an increase in both velocities and heart rates, but a decrease in the duration of atrial systole from early to later stages. At 20-30 hours post fertilization (hpf), simulation results revealed bidirectional WSS across the AV canal in the heart tube in response to peristaltic motion of the wall. At 40-50 hpf, the tube structure undergoes cardiac looping, accompanied by a nearly 3-fold increase in WSS magnitude. At 110-120 hpf, distinct AV valve, atrium, ventricle, and bulbus arteriosus form, accompanied by incremental increases in both WSS magnitude and ∇P, but a decrease in bi-directional flow. Laminar flow develops across the AV canal at 20-30 hpf, and persists at 110-120 hpf. Reynolds numbers at the AV canal increase from 0.07±0.03 at 20-30 hpf to 0.23±0.07 at 110-120 hpf (p< 0.05, n=6), whereas Womersley numbers remain relatively unchanged from 0.11 to 0.13. Our moving domain simulations highlights hemodynamic changes in relation to cardiac morphogenesis; thereby, providing a 2-D quantitative approach to complement imaging analysis. PMID:24009714

  13. Analysis of endoscopic third ventriculostomy patency by MRI: value of different pulse sequences, the sequence parameters, and the imaging planes for investigation of flow void.

    PubMed

    Dinçer, Alp; Yildiz, Erdem; Kohan, Saeed; Memet Özek, M

    2011-01-01

    The aim of the study is to evaluate the efficiency of turbo spin-echo (TSE), three-dimensional constructive interference in the steady state (3D CISS) and cine phase contrast (Cine PC) sequences in determining flow through the endoscopic third ventriculostomy (ETV) fenestration, and to determine the effect of various TSE sequence parameters. The study was approved by our institutional review board and informed consent from all patients was obtained. Two groups of patients were included: group I (24 patients with good clinical outcome after ETV) and group II (22 patients with hydrocephalus evaluated preoperatively). The imaging protocol for both groups was identical. TSE T2 with various sequence parameters and imaging planes, and 3D CISS, followed by cine PC were obtained. Flow void was graded as four-point scales. The sensitivity, specificity, accuracy, positive and negative predictive values of sequences were calculated. Bidirectional flow through the fenestration was detected in all group I patients by cine PC. Stroke volumes through the fenestration in group I ranged 10-160.8 ml/min. There was no correlation between the presence of reversed flow and flow void grading. Also, there was no correlation between the stroke volumes and flow void grading. The sensitivity of 3D CISS was low, and 2 mm sagittal TSE T2, nearly equal to cine PC, provided best result. Cine PC and TSE T2 both have high confidence in the assessment of the flow through the fenestration. But, sequence parameters significantly affect the efficiency of TSE T2.

  14. High-definition flow Doppler ultrasonographic technique to assess hepatic vasculature compared with color or power Doppler ultrasonography: preliminary experience.

    PubMed

    Kim, Se Hyung; Lee, Jeong Min; Kim, Young Jun; Lee, Jae Young; Han, Joon Koo; Choi, Byung Ihn

    2008-10-01

    The purpose of this study was to introduce a new high-definition flow (HDF) Doppler technique and to compare its performance with those of color Doppler ultrasonography (CDU) and power Doppler ultrasonography (PDU) for assessment of hepatic vasculature in native and transplanted livers. High-definition flow was invented as a high-resolution bidirectional PDU technique. We obtained CDU, PDU, and HDF images of the hepatic artery (HA), portal vein (PV), and hepatic vein from 60 patients. They were divided into 2 groups: a liver transplantation group (group 1, n = 10) and a native liver group (group 2, n = 50). Two radiologists independently reviewed the cine images and graded them using a 4-point scale in terms of the clarity of the vessel margin and degree of depiction of the HA, flow filling, and flash artifacts. The degree of differentiation between the HA and PV was also evaluated. Flow directionality was recorded, and interobserver agreement was finally analyzed. Moderate to almost perfect agreement was achieved between radiologists for all parameters of each ultrasonographic technique. High-definition flow was significantly superior to both CDU and PDU with respect to all analyzed items except the degree of flash artifacts (P < .05). With regard to flash artifacts, CDU was significantly better than either PDU or HDF. High-definition flow provided directional information, as did CDU. The HDF technique provides better resolution for depicting hepatic vessels as well as their margins with less blooming compared with conventional Doppler ultrasonography in both native and transplanted liver. It also provides solid directional flow information. One point of concern, however, is the frequency of flash artifacts compared with that on CDU.

  15. Method for evaluating moisture tensions of soils using spectral data

    NASA Technical Reports Server (NTRS)

    Peterson, John B. (Inventor)

    1982-01-01

    A method is disclosed which permits evaluation of soil moisture utilizing remote sensing. Spectral measurements at a plurality of different wavelengths are taken with respect to sample soils and the bidirectional reflectance factor (BRF) measurements produced are submitted to regression analysis for development therefrom of predictable equations calculated for orderly relationships. Soil of unknown reflective and unknown soil moisture tension is thereafter analyzed for bidirectional reflectance and the resulting data utilized to determine the soil moisture tension of the soil as well as providing a prediction as to the bidirectional reflectance of the soil at other moisture tensions.

  16. A thermodynamic analysis of a novel bidirectional district heating and cooling network

    DOE PAGES

    Zarin Pass, R.; Wetter, M.; Piette, M. A.

    2017-11-29

    In this study, we evaluate an ambient, bidirectional thermal network, which uses a single circuit for both district heating and cooling. When in net more cooling is needed than heating, the system circulates from a central plant in one direction. When more heating is needed, the system circulates in the opposite direction. A large benefit of this design is that buildings can recover waste heat from each other directly. We analyze the thermodynamic performance of the bidirectional system. Because the bidirectional system represents the state-of-the-art in design for district systems, its peak energy efficiency represents an upper bound on themore » thermal performance of any district heating and cooling system. However, because any network has mechanical and thermal distribution losses, we develop a diversity criterion to understand when the bidirectional system may be a more energy-efficient alternative to modern individual-building systems. We show that a simple model of a low-density, high-distribution loss network is more efficient than aggregated individual buildings if there is at least 1 unit of cooling energy per 5.7 units of simultaneous heating energy (or vice versa). We apply this criterion to reference building profiles in three cities to look for promising clusters.« less

  17. Bidirectional segmentation of prostate capsule from ultrasound volumes: an improved strategy

    NASA Astrophysics Data System (ADS)

    Wei, Liyang; Narayanan, Ramkrishnan; Kumar, Dinesh; Fenster, Aaron; Barqawi, Albaha; Werahera, Priya; Crawford, E. David; Suri, Jasjit S.

    2008-03-01

    Prostate volume is an indirect indicator for several prostate diseases. Volume estimation is a desired requirement during prostate biopsy, therapy and clinical follow up. Image segmentation is thus necessary. Previously, discrete dynamic contour (DDC) was implemented in orthogonal unidirectional on the slice-by-slice basis for prostate boundary estimation. This suffered from the glitch that it needed stopping criteria during the propagation of segmentation procedure from slice-to-slice. To overcome this glitch, axial DDC was implemented and this suffered from the fact that central axis never remains fixed and wobbles during propagation of segmentation from slice-to-slice. The effect of this was a multi-fold reconstructed surface. This paper presents a bidirectional DDC approach, thereby removing the two glitches. Our bidirectional DDC protocol was tested on a clinical dataset on 28 3-D ultrasound image volumes acquired using side fire Philips transrectal ultrasound. We demonstrate the orthogonal bidirectional DDC strategy achieved the most accurate volume estimation compared with previously published orthogonal unidirectional DDC and axial DDC methods. Compared to the ground truth, we show that the mean volume estimation errors were: 18.48%, 9.21% and 7.82% for unidirectional, axial and bidirectional DDC methods, respectively. The segmentation architecture is implemented in Visual C++ in Windows environment.

  18. Laser Pulse Bidirectional Reflectance from CALIPSO Mission

    NASA Technical Reports Server (NTRS)

    Lu, Xiaomei; Hu, Yongxiang; Yang, Yuekui; Liu, Zhaoyan; Vaughan, Mark; Lucker, Patricia; Trepte, Charles

    2017-01-01

    In this Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) study, we present a simple way of determining laser pulse bidirectional reflectance over snow/ice surface using the Cloud-Aerosol LIdar with Orthogonal Polarization (CALIOP) 532 nanometer polarization channels' measurements. The saturated laser pulse returns from snow and ice surfaces are recovered based on surface tail information. The method overview and initial assessment of the method performance will be presented. The retrieved snow surface bidirectional reflectance is compared with reflectance from both CALIOP cloud cover regions and Moderate Resolution Imaging Spectroradiometer (Earth Observing System (EOS)) (MODIS) Bi-directional Reflectance Distribution Function (BRDF) / Albedo model parameters. The comparisons show that the snow surface bidirectional reflectance over Antarctica for saturation region are generally reliable with a mean value of about 0.90 plus or minus 0.10, while the mean surface reflectance from cloud cover region is about 0.84 plus or minus 0.13 and the calculated MODIS reflectance at 555 nanometers from the BRDF / Albedo model with near nadir illumination and viewing angles is about 0.96 plus or minus 0.04. The comparisons here demonstrate that the snow surface reflectance underneath the cloud with cloud optical depth of about 1 is significantly lower than that for a clear sky condition.

  19. A thermodynamic analysis of a novel bidirectional district heating and cooling network

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zarin Pass, R.; Wetter, M.; Piette, M. A.

    In this study, we evaluate an ambient, bidirectional thermal network, which uses a single circuit for both district heating and cooling. When in net more cooling is needed than heating, the system circulates from a central plant in one direction. When more heating is needed, the system circulates in the opposite direction. A large benefit of this design is that buildings can recover waste heat from each other directly. We analyze the thermodynamic performance of the bidirectional system. Because the bidirectional system represents the state-of-the-art in design for district systems, its peak energy efficiency represents an upper bound on themore » thermal performance of any district heating and cooling system. However, because any network has mechanical and thermal distribution losses, we develop a diversity criterion to understand when the bidirectional system may be a more energy-efficient alternative to modern individual-building systems. We show that a simple model of a low-density, high-distribution loss network is more efficient than aggregated individual buildings if there is at least 1 unit of cooling energy per 5.7 units of simultaneous heating energy (or vice versa). We apply this criterion to reference building profiles in three cities to look for promising clusters.« less

  20. Guide wire assisted catheterization and colored dye injection for vascular mapping of monochorionic twin placentas.

    PubMed

    Jelin, Eric B; Schecter, Samuel C; Gonzales, Kelly D; Hirose, Shinjiro; Lee, Hanmin; Machin, Geoffrey A; Rand, Larry; Feldstein, Vickie A

    2011-09-05

    Monochorionic (MC) twin pregnancies are associated with significantly higher morbidity and mortality rates than dichorionic twins. Approximately 50% of MC twin pregnancies develop complications arising from the shared placenta and associated vascular connections. Severe twin-to-twin syndrome (TTTS) is reported to account for approximately 20% of these complications. Inter-twin vascular connections occur in almost all MC placentas and are related to the prognosis and outcome of these high-risk twin pregnancies. The number, size and type of connections have been implicated in the development of TTTS and other MC twin conditions. Three types of inter-twin vascular connections occur: 1) artery to vein connections (AVs) in which a branch artery carrying deoxygenated blood from one twin courses along the fetal surface of the placenta and dives into a placental cotyledon. Blood flows via a deep intraparenchymal capillary network into a draining vein that emerges at the fetal surface of the placenta and brings oxygenated blood toward the other twin. There is unidirectional flow from the twin supplying the afferent artery toward the twin receiving the efferent vein; 2) artery to artery connections (AAs) in which a branch artery from each twin meets directly on the superficial placental surface resulting in a vessel with pulsatile bidirectional flow, and 3) vein to vein connections (VVs) in which a branch vein from each twin meets directly on the superficial placental surface allowing low pressure bidirectional flow. In utero obstetric sonography with targeted Doppler interrogation has been used to identify the presence of AV and AA connections. Prenatally detected AAs that have been confirmed by postnatal placental injection studies have been shown to be associated with an improved prognosis for both twins. Furthermore, fetoscopic laser ablation of inter-twin vascular connections on the fetal surface of the shared placenta is now the preferred treatment for early, severe TTTS. Postnatal placental injection studies provide a valuable method to confirm the accuracy of prenatal Doppler ultrasound findings and the efficacy of fetal laser therapy. Using colored dyes separately hand-injected into the arterial and venous circulations of each twin, the technique highlights and delineates AVs, AAs, and VVs. This definitive demonstration of MC placental vascular anatomy may then be correlated with Doppler ultrasound findings and neonatal outcome to enhance our understanding of the pathophysiology of MC twinning and its sequelae. Here we demonstrate our placental injection technique.

  1. Design of a Closed-Loop, Bidirectional Brain Machine Interface System With Energy Efficient Neural Feature Extraction and PID Control.

    PubMed

    Liu, Xilin; Zhang, Milin; Richardson, Andrew G; Lucas, Timothy H; Van der Spiegel, Jan

    2017-08-01

    This paper presents a bidirectional brain machine interface (BMI) microsystem designed for closed-loop neuroscience research, especially experiments in freely behaving animals. The system-on-chip (SoC) consists of 16-channel neural recording front-ends, neural feature extraction units, 16-channel programmable neural stimulator back-ends, in-channel programmable closed-loop controllers, global analog-digital converters (ADC), and peripheral circuits. The proposed neural feature extraction units includes 1) an ultra low-power neural energy extraction unit enabling a 64-step natural logarithmic domain frequency tuning, and 2) a current-mode action potential (AP) detection unit with time-amplitude window discriminator. A programmable proportional-integral-derivative (PID) controller has been integrated in each channel enabling a various of closed-loop operations. The implemented ADCs include a 10-bit voltage-mode successive approximation register (SAR) ADC for the digitization of the neural feature outputs and/or local field potential (LFP) outputs, and an 8-bit current-mode SAR ADC for the digitization of the action potential outputs. The multi-mode stimulator can be programmed to perform monopolar or bipolar, symmetrical or asymmetrical charge balanced stimulation with a maximum current of 4 mA in an arbitrary channel configuration. The chip has been fabricated in 0.18 μ m CMOS technology, occupying a silicon area of 3.7 mm 2 . The chip dissipates 56 μW/ch on average. General purpose low-power microcontroller with Bluetooth module are integrated in the system to provide wireless link and SoC configuration. Methods, circuit techniques and system topology proposed in this work can be used in a wide range of relevant neurophysiology research, especially closed-loop BMI experiments.

  2. Bidirectional enantioselective effects of the GABAB receptor agonist baclofen in two mouse models of excessive ethanol consumption

    PubMed Central

    Kasten, Chelsea R.; Blasingame, Shelby N.; Boehm, Stephen L.

    2014-01-01

    The GABAB receptor agonist baclofen has been studied extensively in preclinical models of alcohol use disorders, yet results on its efficacy have been uncertain. Racemic baclofen, which is used clinically, can be broken down into separate enantiomers of the drug. Baclofen has been shown to produce enantioselective effects in behavioral assays including those modeling reflexive and sexual behavior. The current studies sought to characterize the enantioselective effects of baclofen in two separate models of ethanol consumption. The first was a Drinking-in-the-Dark procedure that provides “binge-like” ethanol access to mice by restricting access to a two hour period, three hours into the dark cycle. The second was a two-bottle choice procedure that utilized selectively bred High Alcohol Preferring 1 (HAP1) mice to model chronic ethanol access. HAP1 mice are selectively bred to consume pharmacologically relevant amounts of ethanol in a 24-hour two-bottle choice paradigm. The results showed that baclofen yields enantioselective effects on ethanol intake in both models, and that these effects are bidirectional. Total ethanol intake was decreased by R(+)- baclofen, while total intake was increased by S(-)-baclofen in the binge-like and chronic drinking models. Whereas overall binge-like saccharin intake was significantly reduced by R(+)- baclofen, chronic intake was not significantly altered. S(-)- baclofen did not significantly alter saccharin intake. Neither enantiomer significantly affected locomotion during binge-like reinforcer consumption. Collectively, these results demonstrate that baclofen produces enantioselective effects on ethanol consumption. More importantly, the modulation of consumption is bidirectional. The opposing enantioselective effects may explain some of the variance seen in published baclofen literature. PMID:25557834

  3. Bidirectional enantioselective effects of the GABAB receptor agonist baclofen in two mouse models of excessive ethanol consumption.

    PubMed

    Kasten, Chelsea R; Blasingame, Shelby N; Boehm, Stephen L

    2015-02-01

    The GABAB receptor agonist baclofen has been studied extensively in preclinical models of alcohol-use disorders, yet results on its efficacy have been uncertain. Racemic baclofen, which is used clinically, can be broken down into separate enantiomers of the drug. Baclofen has been shown to produce enantioselective effects in behavioral assays, including those modeling reflexive and sexual behavior. The current studies sought to characterize the enantioselective effects of baclofen in two separate models of ethanol consumption. The first was a Drinking-in-the-Dark procedure that provides "binge-like" ethanol access to mice by restricting access to a 2-h period, 3 h into the dark cycle. The second was a two-bottle choice procedure that utilized selectively bred High Alcohol Preferring 1 (HAP1) mice to model chronic ethanol access. HAP1 mice are selectively bred to consume pharmacologically relevant amounts of ethanol in a 24-h two-bottle choice paradigm. The results showed that baclofen yields enantioselective effects on ethanol intake in both models, and that these effects are bidirectional. Total ethanol intake was decreased by R(+)-baclofen, while total intake was increased by S(-)-baclofen in the binge-like and chronic drinking models. Whereas overall binge-like saccharin intake was significantly reduced by R(+)-baclofen, chronic intake was not significantly altered. S(-)-baclofen did not significantly alter saccharin intake. Neither enantiomer significantly affected locomotion during binge-like reinforcer consumption. Collectively, these results demonstrate that baclofen produces enantioselective effects on ethanol consumption. More importantly, the modulation of consumption is bidirectional. The opposing enantioselective effects may explain some of the variance seen in published baclofen literature. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. The [NiFe]-hydrogenase of the cyanobacterium Synechocystis sp. PCC 6803 works bidirectionally with a bias to H2 production.

    PubMed

    McIntosh, Chelsea L; Germer, Frauke; Schulz, Rüdiger; Appel, Jens; Jones, Anne K

    2011-07-27

    Protein film electrochemistry (PFE) was utilized to characterize the catalytic activity and oxidative inactivation of a bidirectional [NiFe]-hydrogenase (HoxEFUYH) from the cyanobacterium Synechocystis sp. PCC 6803. PFE provides precise control of the redox potential of the adsorbed enzyme so that its activity can be monitored under changing experimental conditions as current. The properties of HoxEFUYH are different from those of both the standard uptake and the "oxygen-tolerant" [NiFe]-hydrogenases. First, HoxEFUYH is biased toward proton reduction as opposed to hydrogen oxidation. Second, despite being expressed under aerobic conditions in vivo, HoxEFUYH is clearly not oxygen-tolerant. Aerobic inactivation of catalytic hydrogen oxidation by HoxEFUYH is total and nearly instantaneous, producing two inactive states. However, unlike the Ni-A and Ni-B inactive states of standard [NiFe]-hydrogenases, both of these states are quickly (<90 s) reactivated by removal of oxygen and exposure to reducing conditions. Third, proton reduction continues at 25-50% of the maximal rate in the presence of 1% oxygen. Whereas most previously characterized [NiFe]-hydrogenases seem to be preferential hydrogen oxidizing catalysts, the cyanobacterial enzyme works effectively in both directions. This unusual catalytic bias as well as the ability to be quickly reactivated may be essential to fulfilling the physiological role in cyanobacteria, organisms expected to experience swings in cellular reduction potential as they switch between aerobic conditions in the light and dark anaerobic conditions. Our results suggest that the uptake [NiFe]-hydrogenases alone are not representative of the catalytic diversity of [NiFe]-hydrogenases, and the bidirectional heteromultimeric enzymes may serve as valuable models to understand the diverse mechanisms of tuning the reactivity of the hydrogen activating site.

  5. Repeated Neck Restraint Stress Bidirectionally Modulates Excitatory Transmission in the Dentate Gyrus and Performance in a Hippocampus-dependent Memory Task.

    PubMed

    Spyrka, Jadwiga; Hess, Grzegorz

    2018-05-21

    The consequences of stress depend on characteristics of the stressor, including the duration of exposure, severity, and predictability. Exposure of mice to repeated neck restraint has been shown to bidirectionally modulate the potential for long-term potentiation (LTP) in the dentate gyrus (DG) in a manner dependent on the number of restraint repetitions, but the influence of repeated brief neck restraint on electrophysiology of single DG neurons has not yet been investigated. Here, we aimed at finding the effects of 1, 3, 7, 14, or 21 daily neck restraint sessions lasting 10 min on electrophysiological characteristics of DG granule cells as well as excitatory and inhibitory synaptic inputs to these neurons. While the excitability of DG granule cells and inhibitory synaptic transmission were unchanged, neck restraint decreased the frequency of spontaneous excitatory currents after three repetitions but enhanced it after 14 and 21 repetitions. The consequences of repeated neck restraint on hippocampus-dependent memory were investigated using the object location test (OLT). Neck restraint stress impaired cognitive performance in the OLT after three repetitions but improved it after 14 and 21 repetitions. Mice subjected to three neck restraint sessions displayed an increase in the measures of depressive and anxiety-like behaviors, however, prolongation of the exposure to neck restraint resulted in a gradual decline in the intensity of these measures. These data indicate that stress imposed by an increasing number of repeated neck restraint episodes bidirectionally modulates both excitatory synaptic transmission in the DG and cognitive performance in the object location memory task. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

  6. Depositional Environments of Late Danian Plant Localities: Chubut Provice, Patagonia, Argentina

    NASA Astrophysics Data System (ADS)

    Comer, E.; Slingerland, R. L.; Wilf, P.

    2010-12-01

    Diverse, well-preserved macroflora are observed within Cretaceous and Paleocene sediments of Chubut Province, Patagonia, Argentina. These macroflora are the most well preserved early Paleocene flora from Gondwana and add new insight into the diversity and environments of that epoch. Two major sites of fossil preservation, Palacio de los Loros and Parque Provincial Ormachea, sit near the top of the Late Danian (65.5-61.7 Ma) Salamanca Formation. Understanding the depositional history of the Salamanca is important in characterizing paleoenvironments in which these flora lived and relating these Patagonian macroflora to concurrent Paleocene flora within the Gondwanan supercontinent. During a two week field season, twenty stratigraphic sections were measured along the outcrop belt at Palacio de los Loros and Ormachea Park as well as two minor sites; Las Flores, and Rancho Grande. Photo mosaics, laser ranger data, and stratigraphic columns were merged with elevated geologic maps and imported into Fledermaus to generate a 3-D visualization of facies relationships. Rock samples were also collected and will be thin sectioned and analyzed for petrography and grain size. The Salamanca Fm. consists of 7 facies, listed here in stratigraphically ascending order: 1)Transgressive sands, 2)Wispy-bedded claystone, 3)Banco Verde, 4)White Cross bedded sandstone, 5)Accretion set siltstone, 6)Transitional silty claystone and 7)Banco Negro. Based on these facies, the Salamanca Fm. is interpreted as a marine-shelf to brackish, tide-dominated, estuarine deposit. The base of the Salamanca Fm. rests on an unconformity representing a marine flooding surface and lower sections of the Salamanca, facies 1 and 2, contain abundant glauconite and fossils indicative of a marine shelf environment. These facies give way upwards to bi-directional trough cross bedded sandstones interspersed with flaser bedded sandy siltstones (facies 3 and 4) indicating a less marine estuary with strong flow regimes and bi-directional currents. Unique features within these two facies such as microdeltas and plane parallel lamination indicate complex micro-environments and flow patterns. Fossil plant remains lie within lateral accretion sets or siltstone facies both above and below the trough cross-bedded sandstone facies. At the top of the Salamanca we reach facies 6 and 7 which transition from sandstone to black mudstone of the Banco Negro. Mammal fossils found in the Banco Negro identify it as a non-marine continental facies. The Late Paleocene Rio Chico formation that overlies the Banco Negro is identified as a continental fluvial formation indicating that facies 6 represents emptying of the estuary and a longstanding regional transition from a marine to a continental environment. To understand the origin of the tidal flows, a paleogeographic model of the Late Danian Patagonian shelf was constructed from facies distributions within the Salamanca Fm. A 2D hydrodynamic model driven by predicted tides in the paleo-Atlantic produces a tidal range of approximately 2m and strong ebb and flood tides throughout the central estuary. These observations are consistent with our interpretation of a meso-tidal estuarine environment as the paleo-flora accumulation site.

  7. Performance analysis and comparison of a minimum interconnections direct storage model with traditional neural bidirectional memories.

    PubMed

    Bhatti, A Aziz

    2009-12-01

    This study proposes an efficient and improved model of a direct storage bidirectional memory, improved bidirectional associative memory (IBAM), and emphasises the use of nanotechnology for efficient implementation of such large-scale neural network structures at a considerable lower cost reduced complexity, and less area required for implementation. This memory model directly stores the X and Y associated sets of M bipolar binary vectors in the form of (MxN(x)) and (MxN(y)) memory matrices, requires O(N) or about 30% of interconnections with weight strength ranging between +/-1, and is computationally very efficient as compared to sequential, intraconnected and other bidirectional associative memory (BAM) models of outer-product type that require O(N(2)) complex interconnections with weight strength ranging between +/-M. It is shown that it is functionally equivalent to and possesses all attributes of a BAM of outer-product type, and yet it is simple and robust in structure, very large scale integration (VLSI), optical and nanotechnology realisable, modular and expandable neural network bidirectional associative memory model in which the addition or deletion of a pair of vectors does not require changes in the strength of interconnections of the entire memory matrix. The analysis of retrieval process, signal-to-noise ratio, storage capacity and stability of the proposed model as well as of the traditional BAM has been carried out. Constraints on and characteristics of unipolar and bipolar binaries for improved storage and retrieval are discussed. The simulation results show that it has log(e) N times higher storage capacity, superior performance, faster convergence and retrieval time, when compared to traditional sequential and intraconnected bidirectional memories.

  8. Does superior caval vein pressure impact head growth in Fontan circulation?

    PubMed

    Trachsel, Tina; Balmer, Christian; Wåhlander, Håkan; Weber, Roland; Dave, Hitendu; Poretti, Andrea; Kretschmar, Oliver; Cavigelli-Brunner, Anna

    2016-10-01

    Patients with bidirectional cavopulmonary anastomosis have unphysiologically high superior caval vein pressure as it equals pulmonary artery pressure. Elevated superior caval vein pressure may cause communicating hydrocephalus and macrocephaly. This study analysed whether there exists an association between head circumference and superior caval vein pressure in patients with single ventricle physiology. We carried out a retrospective analysis of infants undergoing Fontan completion at our institution from 2007 to 2013. Superior caval vein pressures were measured during routine catheterisation before bidirectional cavopulmonary anastomosis and Fontan completion as well as head circumference, adjusted to longitudinal age-dependent percentiles. We included 74 infants in our study. Median ages at bidirectional cavopulmonary anastomosis and Fontan were 4.8 (1.6-12) and 27.9 (7-40.6) months, respectively. Head circumference showed significant growth from bidirectional cavopulmonary anastomosis until Fontan completion (7th (0-100th) versus 20th (0-100th) percentile). There was no correlation between superior caval vein pressure and head circumference before Fontan (R2=0.001). Children with lower differences in superior caval vein pressures between pre-bidirectional cavopulmonary anastomosis and pre-Fontan catheterisations showed increased growth of head circumference (R2=0.19). Patients with moderately elevated superior caval vein pressure associated with single ventricle physiology did not have a tendency to develop macrocephaly. There is no correlation between superior caval vein pressure before Fontan and head circumference, but between bidirectional cavopulmonary anastomosis and Fontan head circumference increases significantly. This may be explained by catch-up growth of head circumference in patients with more favourable haemodynamics and concomitant venous pressures in the lower range. Further studies with focus on high superior caval vein pressures are needed to exclude or prove a correlation.

  9. Preliminary results of BTDF calibration of transmissive solar diffusers for remote sensing

    NASA Astrophysics Data System (ADS)

    Georgiev, Georgi T.; Butler, James J.; Thome, Kurt; Cooksey, Catherine; Ding, Leibo

    2016-09-01

    Satellite instruments operating in the reflected solar wavelength region require accurate and precise determination of the optical properties of their diffusers used in pre-flight and post-flight calibrations. The majority of recent and current space instruments use reflective diffusers. As a result, numerous Bidirectional Reflectance Distribution Function (BRDF) calibration comparisons have been conducted between the National Institute of Standards and Technology (NIST) and other industry and university-based metrology laboratories. However, based on literature searches and communications with NIST and other laboratories, no Bidirectional Transmittance Distribution Function (BTDF) measurement comparisons have been conducted between National Measurement Laboratories (NMLs) and other metrology laboratories. On the other hand, there is a growing interest in the use of transmissive diffusers in the calibration of satellite, air-borne, and ground-based remote sensing instruments. Current remote sensing instruments employing transmissive diffusers include the Ozone Mapping and Profiler Suite instrument (OMPS) Limb instrument on the Suomi-National Polar-orbiting Partnership (S-NPP) platform,, the Geostationary Ocean Color Imager (GOCI) on the Korea Aerospace Research Institute's (KARI) Communication, Ocean, and Meteorological Satellite (COMS), the Ozone Monitoring Instrument (OMI) on NASA's Earth Observing System (EOS) Aura platform, the Tropospheric Emissions: Monitoring of Pollution (TEMPO) instrument and the Geostationary Environmental Monitoring Spectrometer (GEMS).. This ensemble of instruments requires validated BTDF measurements of their onboard transmissive diffusers from the ultraviolet through the near infrared. This paper presents the preliminary results of a BTDF comparison between the NASA Diffuser Calibration Laboratory (DCL) and NIST on quartz and thin Spectralon samples.

  10. An improved low-voltage ride-through performance of DFIG based wind plant using stator dynamic composite fault current limiter.

    PubMed

    Gayen, P K; Chatterjee, D; Goswami, S K

    2016-05-01

    In this paper, an enhanced low-voltage ride-through (LVRT) performance of a grid connected doubly fed induction generator (DFIG) has been presented with the usage of stator dynamic composite fault current limiter (SDCFCL). This protection circuit comprises of a suitable series resistor-inductor combination and parallel bidirectional semiconductor switch. The SDCFCL facilitates double benefits such as reduction of rotor induced open circuit voltage due to increased value of stator total inductance and concurrent increase of rotor impedance. Both effects will limit rotor circuit over current and over voltage situation more secured way in comparison to the conventional scheme like the dynamic rotor current limiter (RCL) during any type of fault situation. The proposed concept is validated through the simulation study of the grid integrated 2.0MW DFIG. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  11. Twelve-hour reproducibility of retinal and optic nerve blood flow parameters in healthy individuals.

    PubMed

    Luksch, Alexandra; Lasta, Michael; Polak, Kaija; Fuchsjäger-Mayrl, Gabriele; Polska, Elzbieta; Garhöfer, Gerhard; Schmetterer, Leopold

    2009-11-01

    The aim of the present study was to investigate the reproducibility and potential diurnal variation of optic nerve head and retinal blood flow parameters in healthy individuals over a period of 12 hr. We measured optic nerve head and retinal blood flow parameters in 16 healthy male non-smoking individuals at five time-points during the day (08:00, 11:00, 14:00, 17:00 and 20:00 hr). Outcome parameters were perimacular white blood cell flux (as assessed with the blue field entoptic technique), blood velocities in retinal veins (as assessed with bi-directional laser Doppler velocimetry), retinal arterial and venous diameters (as assessed with the retinal vessel analyser), optic nerve head blood flow, volume and velocity (as assessed with single point and scanning laser Doppler flowmetry) and blood velocities in the central retinal artery (as assessed with colour Doppler imaging). The coefficient of variation and the maximum change from baseline in an individual were calculated for each outcome parameter. No diurnal variation in optic nerve head or retinal blood flow was observed with any of the techniques employed. Coefficients of variation were between 1.6% and 18.5% for all outcome parameters. The maximum change from baseline in an individual was much higher, ranging from 3.7% to 78.2%. Our data indicate that in healthy individuals the selected techniques provide adequate reproducibility to be used in clinical studies. However, in patients with eye diseases and reduced vision the reproducibility may be considerably worse.

  12. Modeling and Measurements to Improve Bidirectional Exchange in CMAQ

    EPA Science Inventory

    Ammonia, NH3, is an emerging atmospheric pollutant of interest. It is an aerosol precursor and growing constituent of nitrogen deposition. In this presentation, the bidirectional exchange model for NH¬3 in the Community Multiscale Air Quality (CMAQ) model will be reviewed and...

  13. Bidirectional Quantum Teleportation by Using Five-qubit Cluster State

    NASA Astrophysics Data System (ADS)

    Sang, Ming-huang

    2016-03-01

    We propose a scheme for bidirectional quantum teleportation by using a five-qubit cluster state. In our scheme, Alice can transmit an arbitrary two-qubit entangled state to Bob and at the same time Bob can teleport an arbitrary single-qubit state to Alice.

  14. Variable mode bi-directional and uni-directional computer communication system

    DOEpatents

    Cornett, Frank N.; Jenkins, Philip N.; Bowman, Terrance L.; Placek, Joseph M.; Thorson, Gregory M.

    2004-12-14

    A variable communication systems comprising a plurality of transceivers and a control circuit connected to the transceivers to configure the transceivers to operate in a bi-directional mode and a uni-directional mode at different times using different transfer methods to transfer data.

  15. Fluid flow and convective transport of solutes within the intervertebral disc.

    PubMed

    Ferguson, Stephen J; Ito, Keita; Nolte, Lutz P

    2004-02-01

    Previous experimental and analytical studies of solute transport in the intervertebral disc have demonstrated that for small molecules diffusive transport alone fulfils the nutritional needs of disc cells. It has been often suggested that fluid flow into and within the disc may enhance the transport of larger molecules. The goal of the study was to predict the influence of load-induced interstitial fluid flow on mass transport in the intervertebral disc. An iterative procedure was used to predict the convective transport of physiologically relevant molecules within the disc. An axisymmetric, poroelastic finite-element structural model of the disc was developed. The diurnal loading was divided into discrete time steps. At each time step, the fluid flow within the disc due to compression or swelling was calculated. A sequentially coupled diffusion/convection model was then employed to calculate solute transport, with a constant concentration of solute being provided at the vascularised endplates and outer annulus. Loading was simulated for a complete diurnal cycle, and the relative convective and diffusive transport was compared for solutes with molecular weights ranging from 400 Da to 40 kDa. Consistent with previous studies, fluid flow did not enhance the transport of low-weight solutes. During swelling, interstitial fluid flow increased the unidirectional penetration of large solutes by approximately 100%. Due to the bi-directional temporal nature of disc loading, however, the net effect of convective transport over a full diurnal cycle was more limited (30% increase). Further study is required to determine the significance of large solutes and the timing of their delivery for disc physiology.

  16. Submicron bidirectional all-optical plasmonic switches

    PubMed Central

    Chen, Jianjun; Li, Zhi; Zhang, Xiang; Xiao, Jinghua; Gong, Qihuang

    2013-01-01

    Ultra-small all-optical switches are of importance in highly integrated optical communication and computing networks. However, the weak nonlinear light-matter interactions in natural materials present an enormous challenge to realize efficiently switching for the ultra-short interaction lengths. Here, we experimentally demonstrate a submicron bidirectional all-optical plasmonic switch with an asymmetric T-shape single slit. Sharp asymmetric spectra as well as significant field enhancements (about 18 times that in the conventional slit case) occur in the symmetry-breaking structure. Consequently, both of the surface plasmon polaritons propagating in the opposite directions on the metal surface are all-optically controlled inversely at the same time with the on/off switching ratios of >6 dB for the device lateral dimension of <1 μm. Moreover, in such a submicron structure, the coupling of free-space light and the on-chip bidirectional switching are integrated together. This submicron bidirectional all-optical switch may find important applications in the highly integrated plasmonic circuits. PMID:23486232

  17. Spectral bidirectional and hemispherical reflectance characteristics of selected sites in the Streletskaya steppe

    NASA Technical Reports Server (NTRS)

    Eck, Thomas F.; Deering, Donald W.

    1992-01-01

    Measurements of plant canopy bidirectional reflectance made by the PARABOLA (portable apparatus for rapid acquisition of bidirectional observations of the land and atmosphere) instrument in three spectral bands are analyzed for steppe grassland sites of differing productivity levels. The variation of spectral reflectance and the normalized difference vegetation index in the solar principal plane is presented. Comparisons are made with PARABOLA measurements from selected first ISLSCP field experiment (FIFE) grassland sites in the Konza prairie, Kansas. The Streletskaya steppe sites showed no strong hot spot reflectance, while this effect was present in some FIFE sites but absent in others. The hot spot effect seems to be dependent on canopy geometry and background reflectance characteristics of these sites. Spectral hemispherical reflectance was computed from the angular integration of the bidirectional measurements for the steppe sites. Total shortwave albedo was estimated from these hemispherical reflectance measurements and compared to albedo measured by pyranometers. The albedo estimates from PARABOLA were found to be approximately 12-17 percent higher than the pyranometer measurements.

  18. Bidirectionality and compartmentation of metabolic fluxes are revealed in the dynamics of isotopomer networks.

    PubMed

    Schryer, David W; Peterson, Pearu; Paalme, Toomas; Vendelin, Marko

    2009-04-17

    Isotope labeling is one of the few methods of revealing the in vivo bidirectionality and compartmentalization of metabolic fluxes within metabolic networks. We argue that a shift from steady state to dynamic isotopomer analysis is required to deal with these cellular complexities and provide a review of dynamic studies of compartmentalized energy fluxes in eukaryotic cells including cardiac muscle, plants, and astrocytes. Knowledge of complex metabolic behaviour on a molecular level is prerequisite for the intelligent design of genetically modified organisms able to realize their potential of revolutionizing food, energy, and pharmaceutical production. We describe techniques to explore the bidirectionality and compartmentalization of metabolic fluxes using information contained in the isotopic transient, and discuss the integration of kinetic models with MFA. The flux parameters of an example metabolic network were optimized to examine the compartmentalization of metabolites and and the bidirectionality of fluxes in the TCA cycle of Saccharomyces uvarum for steady-state respiratory growth.

  19. Bidirectional automatic release of reserve for low voltage network made with low capacity PLCs

    NASA Astrophysics Data System (ADS)

    Popa, I.; Popa, G. N.; Diniş, C. M.; Deaconu, S. I.

    2018-01-01

    The article presents the design of a bidirectional automatic release of reserve made on two types low capacity programmable logic controllers: PS-3 from Klöckner-Moeller and Zelio from Schneider. It analyses the electronic timing circuits that can be used for making the bidirectional automatic release of reserve: time-on delay circuit and time-off delay circuit (two types). In the paper are present the sequences code for timing performed on the PS-3 PLC, the logical functions for the bidirectional automatic release of reserve, the classical control electrical diagram (with contacts, relays, and time relays), the electronic control diagram (with logical gates and timing circuits), the code (in IL language) made for the PS-3 PLC, and the code (in FBD language) made for Zelio PLC. A comparative analysis will be carried out on the use of the two types of PLC and will be present the advantages of using PLCs.

  20. Reward-timing-dependent bidirectional modulation of cortical microcircuits during optical single-neuron operant conditioning.

    PubMed

    Hira, Riichiro; Ohkubo, Fuki; Masamizu, Yoshito; Ohkura, Masamichi; Nakai, Junichi; Okada, Takashi; Matsuzaki, Masanori

    2014-11-24

    Animals rapidly adapt to environmental change. To reveal how cortical microcircuits are rapidly reorganized when an animal recognizes novel reward contingency, we conduct two-photon calcium imaging of layer 2/3 motor cortex neurons in mice and simultaneously reinforce the activity of a single cortical neuron with water delivery. Here we show that when the target neuron is not relevant to a pre-trained forelimb movement, the mouse increases the target neuron activity and the number of rewards delivered during 15-min operant conditioning without changing forelimb movement behaviour. The reinforcement bidirectionally modulates the activity of subsets of non-target neurons, independent of distance from the target neuron. The bidirectional modulation depends on the relative timing between the reward delivery and the neuronal activity, and is recreated by pairing reward delivery and photoactivation of a subset of neurons. Reward-timing-dependent bidirectional modulation may be one of the fundamental processes in microcircuit reorganization for rapid adaptation.

  1. Homeostatic synaptic depression is achieved through a regulated decrease in presynaptic calcium channel abundance

    PubMed Central

    Gaviño, Michael A; Ford, Kevin J; Archila, Santiago; Davis, Graeme W

    2015-01-01

    Homeostatic signaling stabilizes synaptic transmission at the neuromuscular junction (NMJ) of Drosophila, mice, and human. It is believed that homeostatic signaling at the NMJ is bi-directional and considerable progress has been made identifying mechanisms underlying the homeostatic potentiation of neurotransmitter release. However, very little is understood mechanistically about the opposing process, homeostatic depression, and how bi-directional plasticity is achieved. Here, we show that homeostatic potentiation and depression can be simultaneously induced, demonstrating true bi-directional plasticity. Next, we show that mutations that block homeostatic potentiation do not alter homeostatic depression, demonstrating that these are genetically separable processes. Finally, we show that homeostatic depression is achieved by decreased presynaptic calcium channel abundance and calcium influx, changes that are independent of the presynaptic action potential waveform. Thus, we identify a novel mechanism of homeostatic synaptic plasticity and propose a model that can account for the observed bi-directional, homeostatic control of presynaptic neurotransmitter release. DOI: http://dx.doi.org/10.7554/eLife.05473.001 PMID:25884248

  2. The broadcast classical-quantum capacity region of a two-phase bidirectional relaying channel

    NASA Astrophysics Data System (ADS)

    Boche, Holger; Cai, Minglai; Deppe, Christian

    2015-10-01

    We studied a three-node quantum network that enables bidirectional communication between two nodes with a half-duplex relay node for transmitting classical messages. A decode-and-forward protocol is used to perform the communication in two phases. In the first phase, the messages of two nodes are transmitted to the relay node. The capacity of the first phase is well known by previous works. In the second phase, the relay node broadcasts a re-encoded composition to the two nodes. We determine the capacity region of the broadcast phase. To the best of our knowledge, this is the first paper analyzing quantum bidirectional relay networks.

  3. 5W1H Information Extraction with CNN-Bidirectional LSTM

    NASA Astrophysics Data System (ADS)

    Nurdin, A.; Maulidevi, N. U.

    2018-03-01

    In this work, information about who, did what, when, where, why, and how on Indonesian news articles were extracted by combining Convolutional Neural Network and Bidirectional Long Short-Term Memory. Convolutional Neural Network can learn semantically meaningful representations of sentences. Bidirectional LSTM can analyze the relations among words in the sequence. We also use word embedding word2vec for word representation. By combining these algorithms, we obtained F-measure 0.808. Our experiments show that CNN-BLSTM outperforms other shallow methods, namely IBk, C4.5, and Naïve Bayes with the F-measure 0.655, 0.645, and 0.595, respectively.

  4. Bidirectional optical coupler for plastic optical fibers.

    PubMed

    Sugita, Tatsuya; Abe, Tomiya; Hirano, Kouki; Itoh, Yuzo

    2005-05-20

    We have developed a low-loss bidirectional optical coupler for high-speed optical communication with plastic optical fibers (POFs). The coupler, which is fabricated by an injection molding method that uses poly (methyl methacrylate), has an antisymmetric tapered shape. We show that the coupler has low insertion and branching losses. The tapered shape of the receiving branch reduces beam diameter and increases detection efficiency coupling to a photodetector, whose area is smaller than that of the plastic optical fiber. The possibility of more than 15-m bidirectional transmission with a signaling bit rate up to 500 Mbits/s for simplex step-index POFs is demonstrated.

  5. Nature and Nurturing: Parenting in the Context of Child Temperament

    ERIC Educational Resources Information Center

    Kiff, Cara J.; Lengua, Liliana J.; Zalewski, Maureen

    2011-01-01

    Accounting for both bidirectional and interactive effects between parenting and child temperament can fine-tune theoretical models of the role of parenting and temperament in children's development of adjustment problems. Evidence for bidirectional and interactive effects between parenting and children's characteristics of frustration, fear,…

  6. Estimation of NH3 Bi-Directional Flux from Managed Agricultural Soils

    EPA Science Inventory

    The Community Multi-Scale Air Quality model (CMAQ v4.7) contains a bi-directional ammonia (NH3) flux option that computes emission and deposition of ammonia derived from commercial fertilizer via a temperature dependent parameterization of canopy and soil compensation ...

  7. Advances in Support of the CMAQ Bidirectional Science Option for the Estimation of Ammonia Flux from Agricultural cropland

    EPA Science Inventory

    Proposed Session: Emissions Inventories, Models and processes: Last year a new CMAQ bidirectional option for the estimation of ammonia flux (emission and deposition) was released. This option essentially replaces NEI crop ammonia emissions with emissions calculated dynamically...

  8. Bidirectional relations between work-related stress, sleep quality and perseverative cognition.

    PubMed

    Van Laethem, Michelle; Beckers, Debby G J; Kompier, Michiel A J; Kecklund, Göran; van den Bossche, Seth N J; Geurts, Sabine A E

    2015-11-01

    In this longitudinal two-wave study, bidirectional relations between work-related stress and sleep quality were examined. Moreover, it was investigated whether perseverative cognition is a potential underlying mechanism in this association, related to both work-related stress and sleep quality. A randomly selected sample of Dutch employees received an online survey in 2012 and 2013. Of all invited employees, 877 participated in both waves. Structural equation modeling was performed to analyze the data. We found evidence for reversed relations between work-related stress and sleep quality. Specifically, when controlling for perseverative cognition, work-related stress was not directly related to subsequent sleep quality, but low sleep quality was associated with an increase in work-related stress over time. Moreover, negative bidirectional associations over time were found between perseverative cognition and sleep quality, and positive bidirectional associations were found between work-related stress and perseverative cognition. Lastly, a mediation analysis showed that perseverative cognition fully mediated the relationship between work-related stress and sleep quality. The study findings suggest that perseverative cognition could be an important underlying mechanism in the association between work-related stress and sleep quality. The bidirectionality of the studied relationships could be an indication of a vicious cycle, in which work-related stress, perseverative cognition, and sleep quality mutually influence each other over time. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Bidirectional Relations between Phonological Awareness and Letter Knowledge in Preschool Revisited: A Growth Curve Analysis of the Relation between Two Code-Related Skills

    PubMed Central

    Lerner, Matthew D.; Lonigan, Christopher J.

    2017-01-01

    Despite the importance of phonological awareness for the development of reading in alphabetic languages, little attention has been paid to its developmental origins. In this study, dual-process, latent growth models were used to examine patterns of bidirectional relations between letter knowledge and phonological awareness during preschool. The sample comprised 358 children (mean age = 48.60 months, SD = 7.26). Growth models were used to quantify the unique longitudinal relations between the initial level of each skill and growth in the other skill during the preschool year, after controlling for initial level of the same skill, vocabulary, age, and growth in the code-related skill being used as a predictor. Letter-name knowledge and phonological awareness were bi-directionally related; the initial level of each uniquely predicted growth in the other. Initial letter-sound knowledge and phonological awareness growth were not uniquely related, and vocabulary was not related to growth in phonological awareness. These findings extend the evidence of the relation between letter knowledge and phonological awareness to supra-phonemic tasks, indicating that this bidirectional relation begins at an earlier point in the development of phonological awareness than previously reported. In addition, these findings help to rule out general growth in letter knowledge and phonological awareness as an alternative explanation for the bidirectional relation between these two code-related skills. PMID:26745710

  10. Development and optimization of a matrix converter supplying an electronic ballast - UV lamp system for water sterilization

    NASA Astrophysics Data System (ADS)

    Bokhtache, Aicha Aissa; Zegaoui, Abdallah; Aillerie, Michel; Djahbar, Abdelkader; Hemici, Kheira

    2018-05-01

    Electronic ballasts dedicated to discharge lamps allow improving the quality of radiation by operating at high frequency. In the present work, the use of a single-phase direct converter with a matrix structure for supplying a low-pressure mercury-argon UVC lamp for water sterilization is proposed. The structure of the converter is based on two switching cells allowing the realization of a fully controllable bidirectional switches. The advantages of such a matrix topology include the delivered of a sinusoidal waveform current with a controllable power factor close to unity, variable in amplitude and frequency. In order to obtain the desired amplitude and frequency, a PWM control was associated in the current realization. Finally, a linear adjustment of the lamp arc current was warranted by using of a PI regulator.

  11. A Model of Bidirectional Synaptic Plasticity: From Signaling Network to Channel Conductance

    ERIC Educational Resources Information Center

    Castellani, Gastone C.; Quinlan, Elizabeth M.; Bersani, Ferdinando; Cooper, Leon N.; Shouval, Harel Z.

    2005-01-01

    In many regions of the brain, including the mammalian cortex, the strength of synaptic transmission can be bidirectionally regulated by cortical activity (synaptic plasticity). One line of evidence indicates that long-term synaptic potentiation (LTP) and long-term synaptic depression (LTD), correlate with the phosphorylation/dephosphorylation of…

  12. Generalized chaos synchronization theorems for bidirectional differential equations and discrete systems with applications

    NASA Astrophysics Data System (ADS)

    Ji, Ye; Liu, Ting; Min, Lequan

    2008-05-01

    Two constructive generalized chaos synchronization (GCS) theorems for bidirectional differential equations and discrete systems are introduced. Using the two theorems, one can construct new chaos systems to make the system variables be in GCS. Five examples are presented to illustrate the effectiveness of the theoretical results.

  13. Dismantling the Bidirectional Relationship between Paediatric Sleep and Anxiety

    ERIC Educational Resources Information Center

    Leahy, Erin; Gradisar, Michael

    2012-01-01

    Background: Sleep-related problems are a common occurrence during childhood and adolescence. Over the past decade, there has been mounting evidence for a relationship between sleep disturbance and anxiety during this developmental period. The literature suggests that these associations are likely complex and bidirectional. That is, sleep…

  14. Observations of bi-directional leader development in a triggered lightning flash

    NASA Technical Reports Server (NTRS)

    Laroche, P.; Idone, V.; Eybert-Berard, A.; Barret, L.

    1991-01-01

    Observations of a modified form of rocket triggered lightning are described. A flash triggered during the summer of 1989 is studied as part of an effort to model bidirectional discharge. It is suggested that the altitude triggering technique provides a realistic means of studying the attachment process.

  15. Longitudinal Bidirectional Relations between Adolescents' Sympathy and Prosocial Behavior

    ERIC Educational Resources Information Center

    Carlo, Gustavo; Padilla-Walker, Laura M.; Nielson, Matthew G.

    2015-01-01

    Despite the importance of understanding sympathy and prosocial behaviors, research on the development of these tendencies in adolescence remains relatively sparse. In the present study, we examined age trends and bidirectional longitudinal relations in sympathy and prosocial behaviors across early to middle adolescents. Participants were 500…

  16. MEASUREMENT OF BI-DIRECTIONAL AMMONIA FLUXES OVER SOYBEAN USING MODIFIED BOWEN-RATIO TECHNIQUE

    EPA Science Inventory

    Measurements of bi-directional ammonia exchange over a fertilized soybean canopy are presented for an 8-week period during the summer of 2002. The modified Bowne-ratio approach was used to determine fluxes from vertical NH3 and temperature gradients in combination with eddy covar...

  17. Bidirectional Influences of Violence Exposure and Adjustment in Early Adolescence: Externalizing Behaviors and School Connectedness

    ERIC Educational Resources Information Center

    Mrug, Sylvie; Windle, Michael

    2009-01-01

    This study utilized cross-lagged longitudinal models to examine prospective, bidirectional relationships between witnessing violence and victimization and three adjustment variables--delinquency, conduct problems, and school connectedness. Participants included 603 early adolescent boys and girls (78% African American, 20% Caucasian). Witnessing…

  18. "Advances in Coupled Air Quality, Farm Management and Biogeochemistry to address bidirectional ammonia flux"

    EPA Science Inventory

    A cropland farm management modeling system for regional air quality and field-scale applications of bi-directional ammonia exchange was presented at ITM XXI. The goal of this research is to improve estimates of nitrogen deposition to terrestrial and aquatic ecosystems and ambien...

  19. Bidirectional Modulation of Alcohol-Associated Memory Reconsolidation through Manipulation of Adrenergic Signaling

    PubMed Central

    Schramm, Moritz J W; Everitt, Barry J; Milton, Amy L

    2016-01-01

    Alcohol addiction is a problem of great societal concern, for which there is scope to improve current treatments. One potential new treatment for alcohol addiction is based on disrupting the reconsolidation of the maladaptive Pavlovian memories that can precipitate relapse to drug-seeking behavior. In alcohol self-administering rats, we investigated the effects of bidirectionally modulating adrenergic signaling on the strength of a Pavlovian cue-alcohol memory, using a behavioral procedure that isolates the specific contribution of one maladaptive Pavlovian memory to relapse, the acquisition of a new alcohol-seeking response for an alcohol-associated conditioned reinforcer. The β-adrenergic receptor antagonist propranolol, administered in conjunction with memory reactivation, persistently disrupted the memory that underlies the capacity of a previously alcohol-associated cue to act as a conditioned reinforcer. By contrast, enhancement of adrenergic signaling by administration of the adrenergic prodrug dipivefrin at reactivation increased the strength of the cue-alcohol memory and potentiated alcohol seeking. These data demonstrate the importance of adrenergic signaling in alcohol-associated memory reconsolidation, and suggest a pharmacological target for treatments aiming to prevent relapse through the disruption of maladaptive memories. PMID:26279079

  20. Partners in crime: bidirectional transcription in unstable microsatellite disease.

    PubMed

    Batra, Ranjan; Charizanis, Konstantinos; Swanson, Maurice S

    2010-04-15

    Nearly two decades have passed since the discovery that the expansion of microsatellite trinucleotide repeats is responsible for a prominent class of neurological disorders, including Huntington disease and fragile X syndrome. These hereditary diseases are characterized by genetic anticipation or the intergenerational increase in disease severity accompanied by a decrease in age-of-onset. The revelation that the variable expansion of simple sequence repeats accounted for anticipation spawned a number of pathogenesis models and a flurry of studies designed to reveal the molecular events affected by these expansions. This work led to our current understanding that expansions in protein-coding regions result in extended homopolymeric amino acid tracts, often polyglutamine or polyQ, and deleterious protein gain-of-function effects. In contrast, expansions in noncoding regions cause RNA-mediated toxicity. However, the realization that the transcriptome is considerably more complex than previously imagined, as well as the emerging regulatory importance of antisense RNAs, has blurred this distinction. In this review, we summarize evidence for bidirectional transcription of microsatellite disease genes and discuss recent suggestions that some repeat expansions produce variable levels of both toxic RNAs and proteins that influence cell viability, disease penetrance and pathological severity.

  1. National Institute of Standards and Technology measurement service of the optical properties of biomedical phantoms: Current status.

    PubMed

    Lemaillet, Paul; Cooksey, Catherine C; Levine, Zachary H; Pintar, Adam L; Hwang, Jeeseong; Allen, David W

    2016-03-24

    The National Institute of Standards and Technology (NIST) has maintained scales for reflectance and transmittance over several decades. The scales are primarily intended for regular transmittance, mirrors, and solid surface scattering diffusers. The rapidly growing area of optical medical imaging needs a scale for volume scattering of diffuse materials that are used to mimic the optical properties of tissue. Such materials are used as phantoms to evaluate and validate instruments under development intended for clinical use. To address this need, a double-integrating sphere based instrument has been installed to measure the optical properties of tissue-mimicking phantoms. The basic system and methods have been described in previous papers. An important attribute in establishing a viable calibration service is the estimation of measurement uncertainties. The use of custom models and comparisons with other established scales enabled uncertainty measurements. Here, we describe the continuation of those efforts to advance the understanding of the uncertainties through two independent measurements: the bidirectional reflectance distribution function and the bidirectional transmittance distribution function of a commercially available solid biomedical phantom. A Monte Carlo-based model is used and the resulting optical properties are compared to the values provided by the phantom manufacturer.

  2. Anisotropy of the Seebeck Coefficient in the Cuprate Superconductor YBa2 Cu3 Oy : Fermi-Surface Reconstruction by Bidirectional Charge Order

    NASA Astrophysics Data System (ADS)

    Cyr-Choinière, O.; Badoux, S.; Grissonnanche, G.; Michon, B.; Afshar, S. A. A.; Fortier, S.; LeBoeuf, D.; Graf, D.; Day, J.; Bonn, D. A.; Hardy, W. N.; Liang, R.; Doiron-Leyraud, N.; Taillefer, Louis

    2017-07-01

    The Seebeck coefficient S of the cuprate YBa2 Cu3 Oy is measured in magnetic fields large enough to suppress superconductivity, at hole dopings p =0.11 and p =0.12 , for heat currents along the a and b directions of the orthorhombic crystal structure. For both directions, S /T decreases and becomes negative at low temperature, a signature that the Fermi surface undergoes a reconstruction due to broken translational symmetry. Above a clear threshold field, a strong new feature appears in Sb, for conduction along the b axis only. We attribute this feature to the onset of 3D-coherent unidirectional charge-density-wave modulations seen by x-ray diffraction, also along the b axis only. Because these modulations have a sharp onset temperature well below the temperature where S /T starts to drop towards negative values, we infer that they are not the cause of Fermi-surface reconstruction. Instead, the reconstruction must be caused by the quasi-2D bidirectional modulations that develop at significantly higher temperature. The unidirectional order only confers an additional anisotropy to the already reconstructed Fermi surface, also manifest as an in-plane anisotropy of the resistivity.

  3. Platforms for hyperspectral imaging, in-situ optical and acoustical imaging in urbanized regions

    NASA Astrophysics Data System (ADS)

    Bostater, Charles R.; Oney, Taylor

    2016-10-01

    Hyperspectral measurements of the water surface of urban coastal waters are presented. Oblique bidirectional reflectance factor imagery was acquired made in a turbid coastal sub estuary of the Indian River Lagoon, Florida and along coastal surf zone waters of the nearby Atlantic Ocean. Imagery was also collected using a pushbroom hyperspectral imager mounted on a fixed platform with a calibrated circular mechatronic rotation stage. Oblique imagery of the shoreline and subsurface features clearly shows subsurface bottom features and rip current features within the surf zone water column. In-situ hyperspectral optical signatures were acquired from a vessel as a function of depth to determine the attenuation spectrum in Palm Bay. A unique stationary platform methodology to acquire subsurface acoustic images showing the presence of moving bottom boundary nephelometric layers passing through the acoustic fan beam. The acoustic fan beam imagery indicated the presence of oscillatory subsurface waves in the urbanized coastal estuary. Hyperspectral imaging using the fixed platform techniques are being used to collect hyperspectral bidirectional reflectance factor (BRF) measurements from locations at buildings and bridges in order to provide new opportunities to advance our scientific understanding of aquatic environments in urbanized regions.

  4. NOVA: A new multi-level logic simulator

    NASA Technical Reports Server (NTRS)

    Miles, L.; Prins, P.; Cameron, K.; Shovic, J.

    1990-01-01

    A new logic simulator that was developed at the NASA Space Engineering Research Center for VLSI Design was described. The simulator is multi-level, being able to simulate from the switch level through the functional model level. NOVA is currently in the Beta test phase and was used to simulate chips designed for the NASA Space Station and the Explorer missions. A new algorithm was devised to simulate bi-directional pass transistors and a preliminary version of the algorithm is presented. The usage of functional models in NOVA is also described and performance figures are presented.

  5. Associations between Parenting Behaviors and Adolescent Romantic Relationships

    PubMed Central

    Auslander, Beth A.; Short, Mary B.; Succop, Paul A.; Rosenthal, Susan L.

    2014-01-01

    We examined associations between parenting behaviors and romantic relationship qualities in 102 adolescent girls (14–21 years) who lived with their parent/parental figure and had current boyfriends. Adolescent girls’ perceptions that parents were accepting/involved and provided appropriate strictness and supervision were significantly related to adolescent girls’ perceptions of mutuality (i.e., bidirectional movement of thoughts, feelings, and activities between persons) [1] within their own romantic relationships which in turn was related to their romantic relationship satisfaction. No parenting variables were related to non-exclusivity. PMID:19541257

  6. Point Pairing Method Based on the Principle of Material Frame Indifference for the Characterization of Unknown Space Objects using Non-Resolved Photometry Data

    DTIC Science & Technology

    2013-09-01

    provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB...the satellite. The material constitutive laws of interest are the bidirectional reflectance distribution functions ( BRDF ) for diffuse and specular...solar panel can be related to each other using the BRDF definition. This creates a set of three independent equations and three unknowns, which can be

  7. Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?

    PubMed

    Yulug, Burak; Hanoglu, Lutfu; Kilic, Ertugrul

    2017-10-01

    Sleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms of amyloid beta (Aβ) clearance metabolism. Here, we aimed to evaluate the current evidence on the role of sleep deprivation in Aβ clearance metabolism. To that end, we discuss possible mechanisms underlying the bidirectional interaction between the sleep deprivation and Aβ clearance pathways. © 2017 The Authors. Psychiatry and Clinical Neurosciences © 2017 Japanese Society of Psychiatry and Neurology.

  8. Rectification of Spatial Disorder

    NASA Astrophysics Data System (ADS)

    Um, Jaegon; Hong, Hyunsuk; Marchesoni, Fabio; Park, Hyunggyu

    2012-02-01

    We demonstrate that a large ensemble of noiseless globally coupled-pinned oscillators is capable of rectifying spatial disorder with spontaneous current activated through a dynamical phase transition mechanism, either of first or second order, depending on the profile of the pinning potential. In the presence of an external weak drive, the same collective mechanism can result in an absolute negative mobility, which, though not immediately related to symmetry breaking, is most prominent at the phase transition. Our results apply to a tug-of-war by competing molecular motors for bidirectional cargo transport.

  9. Permanent magnet flux-biased magnetic actuator with flux feedback

    NASA Technical Reports Server (NTRS)

    Groom, Nelson J. (Inventor)

    1991-01-01

    The invention is a permanent magnet flux-biased magnetic actuator with flux feedback for adjustably suspending an element on a single axis. The magnetic actuator includes a pair of opposing electromagnets and provides bi-directional forces along the single axis to the suspended element. Permanent magnets in flux feedback loops from the opposing electromagnets establish a reference permanent magnet flux-bias to linearize the force characteristics of the electromagnets to extend the linear range of the actuator without the need for continuous bias currents in the electromagnets.

  10. Investigation of interface property in Al/SiO2/ n-SiC structure with thin gate oxide by illumination

    NASA Astrophysics Data System (ADS)

    Chang, P. K.; Hwu, J. G.

    2017-04-01

    The reverse tunneling current of Al/SiO2/ n-SiC structure employing thin gate oxide is introduced to examine the interface property by illumination. The gate current at negative bias decreases under blue LED illumination, yet increases under UV lamp illumination. Light-induced electrons captured by interface states may be emitted after the light sources are off, leading to the recovery of gate currents. Based on transient characteristics of gate current, the extracted trap level is close to the light energy for blue LED, indicating that electron capture induced by lighting may result in the reduction of gate current. Furthermore, bidirectional C- V measurements exhibit a positive voltage shift caused by electron trapping under blue LED illumination, while a negative voltage shift is observed under UV lamp illumination. Distinct trapping and detrapping behaviors can be observed from variations in I- V and C- V curves utilizing different light sources for 4H-SiC MOS capacitors with thin insulators.

  11. Regulation of amniotic fluid volume: mathematical model based on intramembranous transport mechanisms

    PubMed Central

    Anderson, Debra F.; Cheung, Cecilia Y.

    2014-01-01

    Experimentation in late-gestation fetal sheep has suggested that regulation of amniotic fluid (AF) volume occurs primarily by modulating the rate of intramembranous transport of water and solutes across the amnion into underlying fetal blood vessels. In order to gain insight into intramembranous transport mechanisms, we developed a computer model that allows simulation of experimentally measured changes in AF volume and composition over time. The model included fetal urine excretion and lung liquid secretion as inflows into the amniotic compartment plus fetal swallowing and intramembranous absorption as outflows. By using experimental flows and solute concentrations for urine, lung liquid, and swallowed fluid in combination with the passive and active transport mechanisms of the intramembranous pathway, we simulated AF responses to basal conditions, intra-amniotic fluid infusions, fetal intravascular infusions, urine replacement, and tracheoesophageal occlusion. The experimental data are consistent with four intramembranous transport mechanisms acting in concert: 1) an active unidirectional bulk transport of AF with all dissolved solutes out of AF into fetal blood presumably by vesicles; 2) passive bidirectional diffusion of solutes, such as sodium and chloride, between fetal blood and AF; 3) passive bidirectional water movement between AF and fetal blood; and 4) unidirectional transport of lactate into the AF. Further, only unidirectional bulk transport is dynamically regulated. The simulations also identified areas for future study: 1) identifying intramembranous stimulators and inhibitors, 2) determining the semipermeability characteristics of the intramembranous pathway, and 3) characterizing the vesicles that are the primary mediators of intramembranous transport. PMID:25186112

  12. Description of a 20 kilohertz power distribution system

    NASA Technical Reports Server (NTRS)

    Hansen, I. G.

    1986-01-01

    A single phase, 440 VRMS, 20 kHz power distribution system with a regulated sinusoidal wave form is discussed. A single phase power system minimizes the wiring, sensing, and control complexities required in a multi-sourced redundantly distributed power system. The single phase addresses only the distribution links multiphase lower frequency inputs and outputs accommodation techniques are described. While the 440 V operating potential was initially selected for aircraft operating below 50,000 ft, this potential also appears suitable for space power systems. This voltage choice recognizes a reasonable upper limit for semiconductor ratings, yet will direct synthesis of 220 V, 3 power. A 20 kHz operating frequency was selected to be above the range of audibility, minimize the weight of reactive components, yet allow the construction of single power stages of 25 to 30 kW. The regulated sinusoidal distribution system has several advantages. With a regulated voltage, most ac/dc conversions involve rather simple transformer rectifier applications. A sinusoidal distribution system, when used in conjunction with zero crossing switching, represents a minimal source of EMI. The present state of 20 kHz power technology includes computer controls of voltage and/or frequency, low inductance cable, current limiting circuit protection, bi-directional power flow, and motor/generator operating using standard induction machines. A status update and description of each of these items and their significance is presented.

  13. Description of a 20 Kilohertz power distribution system

    NASA Technical Reports Server (NTRS)

    Hansen, I. G.

    1986-01-01

    A single phase, 440 VRMS, 20 kHz power distribution system with a regulated sinusoidal wave form is discussed. A single phase power system minimizes the wiring, sensing, and control complexities required in a multi-sourced redundantly distributed power system. The single phase addresses only the distribution link; mulitphase lower frequency inputs and outputs accommodation techniques are described. While the 440 V operating potential was initially selected for aircraft operating below 50,000 ft, this potential also appears suitable for space power systems. This voltage choice recognizes a reasonable upper limit for semiconductor ratings, yet will direct synthesis of 220 V, 3 power. A 20 kHz operating frequency was selected to be above the range of audibility, minimize the weight of reactive components, yet allow the construction of single power stages of 25 to 30 kW. The regulated sinusoidal distribution system has several advantages. With a regulated voltage, most ac/dc conversions involve rather simple transformer rectifier applications. A sinusoidal distribution system, when used in conjunction with zero crossing switching, represents a minimal source of EMI. The present state of 20 kHz power technology includes computer controls of voltage and/or frequency, low inductance cable, current limiting circuit protection, bi-directional power flow, and motor/generator operating using standard induction machines. A status update and description of each of these items and their significance is presented.

  14. Stability analysis for stochastic BAM nonlinear neural network with delays

    NASA Astrophysics Data System (ADS)

    Lv, Z. W.; Shu, H. S.; Wei, G. L.

    2008-02-01

    In this paper, stochastic bidirectional associative memory neural networks with constant or time-varying delays is considered. Based on a Lyapunov-Krasovskii functional and the stochastic stability analysis theory, we derive several sufficient conditions in order to guarantee the global asymptotically stable in the mean square. Our investigation shows that the stochastic bidirectional associative memory neural networks are globally asymptotically stable in the mean square if there are solutions to some linear matrix inequalities(LMIs). Hence, the global asymptotic stability of the stochastic bidirectional associative memory neural networks can be easily checked by the Matlab LMI toolbox. A numerical example is given to demonstrate the usefulness of the proposed global asymptotic stability criteria.

  15. Angular radiation models for Earth-atmosphere system. Volume 1: Shortwave radiation

    NASA Technical Reports Server (NTRS)

    Suttles, J. T.; Green, R. N.; Minnis, P.; Smith, G. L.; Staylor, W. F.; Wielicki, B. A.; Walker, I. J.; Young, D. F.; Taylor, V. R.; Stowe, L. L.

    1988-01-01

    Presented are shortwave angular radiation models which are required for analysis of satellite measurements of Earth radiation, such as those fro the Earth Radiation Budget Experiment (ERBE). The models consist of both bidirectional and directional parameters. The bidirectional parameters are anisotropic function, standard deviation of mean radiance, and shortwave-longwave radiance correlation coefficient. The directional parameters are mean albedo as a function of Sun zenith angle and mean albedo normalized to overhead Sun. Derivation of these models from the Nimbus 7 ERB (Earth Radiation Budget) and Geostationary Operational Environmental Satellite (GOES) data sets is described. Tabulated values and computer-generated plots are included for the bidirectional and directional modes.

  16. Colours sometimes count: awareness and bidirectionality in grapheme-colour synaesthesia.

    PubMed

    Johnson, Addie; Jepma, Marieke; de Jong, Ritske

    2007-10-01

    Three experiments were conducted with 10 grapheme-colour synaesthetes and 10 matched controls to investigate (a) whether awareness of the inducer grapheme is necessary for synaesthetic colour induction and (b) whether grapheme-colour synaesthesia may be bidirectional in the sense that not only do graphemes induce colours, but that colours influence the processing of graphemes. Using attentional blink and Stroop paradigms with digit targets, we found that some synaesthetes did report "seeing" synaesthetic colours even when they were not able to report the inducing digit. Moreover, congruency effects (effects of matching the colour of digit presentation with the synaesthetic colour associated with that digit) suggested that grapheme-colour synaesthesia can be bidirectional, at least for some synaesthetes.

  17. Urban runoff (URO) process for MODFLOW 2005: simulation of sub-grid scale urban hydrologic processes in Broward County, FL

    USGS Publications Warehouse

    Decker, Jeremy D.; Hughes, J.D.

    2013-01-01

    Climate change and sea-level rise could cause substantial changes in urban runoff and flooding in low-lying coast landscapes. A major challenge for local government officials and decision makers is to translate the potential global effects of climate change into actionable and cost-effective adaptation and mitigation strategies at county and municipal scales. A MODFLOW process is used to represent sub-grid scale hydrology in urban settings to help address these issues. Coupled interception, surface water, depression, and unsaturated zone storage are represented. A two-dimensional diffusive wave approximation is used to represent overland flow. Three different options for representing infiltration and recharge are presented. Additional features include structure, barrier, and culvert flow between adjacent cells, specified stage boundaries, critical flow boundaries, source/sink surface-water terms, and the bi-directional runoff to MODFLOW Surface-Water Routing process. Some abilities of the Urban RunOff (URO) process are demonstrated with a synthetic problem using four land uses and varying cell coverages. Precipitation from a hypothetical storm was applied and cell by cell surface-water depth, groundwater level, infiltration rate, and groundwater recharge rate are shown. Results indicate the URO process has the ability to produce time-varying, water-content dependent infiltration and leakage, and successfully interacts with MODFLOW.

  18. ROLE OF LEAF SURFACE WATER IN THE BI-DIRECTIONAL AMMONIA EXCHANGE BETWEEN THE ATMOSPHERE AND TERRESTRIAL BIOSPHERE

    EPA Science Inventory

    A field experiment was conducted to study the ammonia exchange between plants and the atmosphere in a soybean field in Duplin County, North Carolina during the summer of 2002. Measurements indicate that the net canopy-scale ammonia exchange is bi-directional and has a significant...

  19. Bidirectional Partner Violence among Homeless Young Adults: Risk Factors and Outcomes

    ERIC Educational Resources Information Center

    Tyler, Kimberly A.; Melander, Lisa A.; Noel, HarmoniJoie

    2009-01-01

    One of the most prevalent forms of violence in contemporary society is the victimization of intimate partners. Although it has been established that homeless young people experience high levels of victimization on the street, little is known about partner violence (PV) experiences among this group, especially bidirectional violence. As such, the…

  20. Bidirectional Cross-Linguistic Influence in Cantonese-English Bilingual Children: The Case of Right-Dislocation

    ERIC Educational Resources Information Center

    Ge, Haoyan; Matthews, Stephen; Cheung, Lawrence Yam-leung; Yip, Virginia

    2017-01-01

    This corpus-based study demonstrates a case of bidirectional cross-linguistic influence in the acquisition of right-dislocation by Cantonese-English bilingual children and interprets the results in relation to Hulk and Müller's hypothesis for cross-linguistic influence. Longitudinal data reveal qualitative and quantitative differences between…

  1. Bidirectional Associations in Multiplication Memory: Conditions of Negative and Positive Transfer

    ERIC Educational Resources Information Center

    Campbell, Jamie I. D.; Robert, Nicole D.

    2008-01-01

    A variety of experimental evidence indicates that the memory representation for multiplication facts (e.g., 6 [times] 9 = 54) incorporates bidirectional links with a forward association from factors to product and a reverse association from product to factors. Surprisingly, the authors did not find evidence in Experiment 1 of facilitative…

  2. Bidirectional Influences between Maternal and Paternal Parenting and Children's Disruptive Behaviour from Kindergarten to Grade 2

    ERIC Educational Resources Information Center

    Besnard, Therese; Verlaan, Pierrette; Davidson, Marilyne; Vitaro, Frank; Poulin, Francois; Capuano, France

    2013-01-01

    Empirical evidence suggests that children's disruptive behaviour (CDB) and quality of parenting influence one another bidirectionally. However, few studies have considered the separate contribution of the mother--child and father--child relationships to disruptive behaviours within a longitudinal context. Against this background, the reciprocal…

  3. Parenting and Children's Externalizing Behavior: Bidirectionality during Toddlerhood

    ERIC Educational Resources Information Center

    Verhoeven, Marjolein; Junger, Marianne; van Aken, Chantal; Dekovic, Maja; van Aken, Marcel A. G.

    2010-01-01

    This study examined the bidirectional relationship between parenting and boys' externalizing behaviors in a four-wave longitudinal study of toddlers. Participants were 104 intact two-parent families with toddler sons. When their sons were 17, 23, 29, and 35 months of age, mothers and fathers reported on a broad range of parenting dimensions…

  4. "Figuring" Bidirectional Home and School Connections along the Biliteracy Continuum

    ERIC Educational Resources Information Center

    Fránquiz, María E.; Leija, María G.; Garza, Irene

    2015-01-01

    This article centers on the significant practices identified by bilingual teachers who participated in Proyecto Bilingüe, a specialized master's degree program. The notion of bidirectional theory of bilingual pedagogy and the theoretical construct of the continua of biliteracy are utilized to illustrate how the teachers centered home and school…

  5. Poor School Bonding and Delinquency over Time: Bidirectional Effects and Sex Differences

    ERIC Educational Resources Information Center

    Liljeberg, Jenny Freidenfelt; Eklund, Jenny M.; Fritz, Marie Vafors; Klinteberg, Britt af

    2011-01-01

    The association between poor school bonding and delinquency has only been partly addressed in earlier research. Using a longitudinal design, the objective of our study was to investigate possible bidirectional effects and sex differences between adolescents' experienced school bonding and self-rated delinquency over time. A total of 788…

  6. Model-measurement comparison of ammonia bi-directional air-surface exchange fluxes over agricultural fields

    EPA Science Inventory

    Modeling of the bi-directional fluxes (BDFs) of ammonia (NH3) over fertilized soybean and corn canopies was evaluated for three intensive sampling periods: the first, during the summer of 2002 in Warsaw, North Carolina (NC), USA; and the second and third during the summer of 2007...

  7. Bidirectional Associations among Sensitive Parenting, Language Development, and Social Competence

    ERIC Educational Resources Information Center

    Barnett, Melissa A.; Gustafsson, Hanna; Deng, Min; Mills-Koonce, W. Roger; Cox, Martha

    2012-01-01

    Rapid changes in language skills and social competence, both of which are linked to sensitive parenting, characterize early childhood. The present study examines bidirectional associations among mothers' sensitive parenting and children's language skills and social competence from 24 to 36?months in a community sample of 174 families. In addition,…

  8. Multispectral Resource Sampler: Proof of concept. Literature survey of bidirectional reflectance

    NASA Technical Reports Server (NTRS)

    1981-01-01

    A bibliography compiled in order to give a comprehensive review of previous work in scene bidirectional reflectance, particularly those studies relevant to the Multispectral Resource Sampler (MRS) is presented. The bibliography contains 124 abstracts. In addition a synthesis of the literature results is given along with background information concerning MRS.

  9. Longitudinal Bi-Directional Relationships between Sleep and Youth Substance Use

    ERIC Educational Resources Information Center

    Pasch, Keryn E.; Latimer, Lara A.; Cance, Jessica Duncan; Moe, Stacey G.; Lytle, Leslie A.

    2012-01-01

    Despite the known deficits in sleep that occur during adolescence and the high prevalence of substance use behaviors among this group, relatively little research has explored how sleep and substance use may be causally related. The purpose of this study was to explore the longitudinal bi-directional relationships between sleep duration, sleep…

  10. Cellular mechanisms underlying behavioral state-dependent bidirectional modulation of motor cortex output.

    PubMed

    Schiemann, Julia; Puggioni, Paolo; Dacre, Joshua; Pelko, Miha; Domanski, Aleksander; van Rossum, Mark C W; Duguid, Ian

    2015-05-26

    Neuronal activity in primary motor cortex (M1) correlates with behavioral state, but the cellular mechanisms underpinning behavioral state-dependent modulation of M1 output remain largely unresolved. Here, we performed in vivo patch-clamp recordings from layer 5B (L5B) pyramidal neurons in awake mice during quiet wakefulness and self-paced, voluntary movement. We show that L5B output neurons display bidirectional (i.e., enhanced or suppressed) firing rate changes during movement, mediated via two opposing subthreshold mechanisms: (1) a global decrease in membrane potential variability that reduced L5B firing rates (L5Bsuppressed neurons), and (2) a coincident noradrenaline-mediated increase in excitatory drive to a subpopulation of L5B neurons (L5Benhanced neurons) that elevated firing rates. Blocking noradrenergic receptors in forelimb M1 abolished the bidirectional modulation of M1 output during movement and selectively impaired contralateral forelimb motor coordination. Together, our results provide a mechanism for how noradrenergic neuromodulation and network-driven input changes bidirectionally modulate M1 output during motor behavior. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  11. Bidirectional associations in multiplication memory: conditions of negative and positive transfer.

    PubMed

    Campbell, Jamie I D; Robert, Nicole D

    2008-05-01

    A variety of experimental evidence indicates that the memory representation for multiplication facts (e.g., 6 x 9 = 54) incorporates bidirectional links with a forward association from factors to product and a reverse association from product to factors. Surprisingly, the authors did not find evidence in Experiment 1 of facilitative transfer-of-practice from multiplication (6 x 9 = ?) to factoring (54 = ? x ?); in fact, multiplication practice produced item-specific interference with factoring. Similarly, the authors found no evidence in Experiment 2 that repetition of specific factoring problems (54 = ? x ?) facilitated performance of corresponding multiplication problems (6 x 9 = ?). In Experiment 3, participants practiced both multiplication and factoring and presented facilitative transfer in both directions. Thus, bidirectional facilitation occurred if both operations were practiced, but interference occurred when only one operation was practiced. We propose that this seemingly paradoxical behavior occurs because it is adaptive for the bidirectional retrieval structure to retain operational flexibility in the context of practicing both operations, whereas it is adaptive to specialize the memory representation for the practiced operation (i.e., factoring or multiplication) when only one operation is practiced.

  12. Unravelling how βCaMKII controls the direction of plasticity at parallel fibre-Purkinje cell synapses

    NASA Astrophysics Data System (ADS)

    Pinto, Thiago M.; Schilstra, Maria J.; Steuber, Volker; Roque, Antonio C.

    2015-12-01

    Long-term plasticity at parallel fibre (PF)-Purkinje cell (PC) synapses is thought to mediate cerebellar motor learning. It is known that calcium-calmodulin dependent protein kinase II (CaMKII) is essential for plasticity in the cerebellum. Recently, Van Woerden et al. demonstrated that the β isoform of CaMKII regulates the bidirectional inversion of PF-PC plasticity. Because the cellular events that underlie these experimental findings are still poorly understood, our work aims at unravelling how β CaMKII controls the direction of plasticity at PF-PC synapses. We developed a bidirectional plasticity model that replicates the experimental observations by Van Woerden et al. Simulation results obtained from this model indicate the mechanisms that underlie the bidirectional inversion of cerebellar plasticity. As suggested by Van Woerden et al., the filamentous actin binding enables β CaMKII to regulate the bidirectional plasticity at PF-PC synapses. Our model suggests that the reversal of long-term plasticity in PCs is based on a combination of mechanisms that occur at different calcium concentrations.

  13. Development of a bi-directional standing wave linear piezoelectric actuator with four driving feet.

    PubMed

    Liu, Yingxiang; Shi, Shengjun; Li, Chunhong; Chen, Weishan; Wang, Liang; Liu, Junkao

    2018-03-01

    A bi-directional standing wave linear piezoelectric ultrasonic actuator with four driving feet is proposed in this work. Two sandwich type transducers operated in longitudinal-bending hybrid modes are set parallelly. The working mode of the transducer is not simple hybrid vibrations of a longitudinal one and a bending one, but a special coupling vibration mode contained both longitudinal and bending components. Two transducers with the same structure and unsymmetrical boundary conditions are set parallelly to accomplish the bi-directional driving: the first transducer can push the runner forward, while the other one produces the backward driving. In the experiments, two voltages with different amplitudes are applied on the two transducers, respectively: the one with higher voltage serves as the actuator, whereas the other one applied with lower voltage is used to reduce the frictional force. The prototype achieves maximum no-load speed and thrust force of 244 mm/s and 9.8 N. This work gives a new idea for the construction of standing wave piezoelectric ultrasonic actuator with bi-directional driving ability. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Bidirectional semantic associations between social power and weight.

    PubMed

    He, Xiaoling; Chen, Jun; Li, Jianan

    2018-02-01

    Two experiments were conducted to examine bidirectional semantic associations between power and weight using a priming paradigm. Bidirectionality in the relationship between power and weight was demonstrated, utilising tasks that were identical except that the orders in which the stimuli were presented were reversed. In Experiment 1, an empty scale leaning either leftward or rightward was used as a priming stimulus, and a scale that appeared in equilibrium with a pair of power words was used as a target stimulus. In Experiment 2, a scale with a pair of words that appeared in equilibrium was used as a priming stimulus, and an empty scale leaning either leftward or rightward was used as a target stimulus. We identified interaction effects between power and weight in both experiments. Associations between power and weight provide evidence for both conceptual metaphor views and evolutionary theory. The bidirectionality of metaphorical effects is in line with the strong version of metaphoric structuring. Both language and experiential correlations play important roles in the development of the mapping between power and weight. © 2016 International Union of Psychological Science.

  15. Bidirectional reflectance modeling of non-homogeneous plant canopies

    NASA Technical Reports Server (NTRS)

    Norman, John M.

    1986-01-01

    The objective of this research is to develop a 3-dimensional radiative transfer model for predicting the bidirectional reflectance distribution function (BRDF) for heterogeneous vegetation canopies. Leaf bidirectional reflectance and transmittance distribution functions were measured for corn and soybean leaves. The measurements clearly show that leaves are complex scatterers and considerable specular reflectance is possible. Because of the character of leaf reflectance, true leaf reflectance is larger than the nadir reflectances that are normally used to represent leaves. A 3-dimensional reflectance model, named BIGAR (Bidirectional General Array Model), was developed and compared with measurements from corn and soybean. The model is based on the concept that heterogeneous canopies can be described by a combination of many subcanopies, which contain all the foliage, and these subcanopy envelopes can be characterized by ellipsoids of various sizes and shapes. The model/measurement comparison results indicate that this relatively simple model captures the essential character of row crop BRDF's. Finally, two soil BDRF models were developed: one represents soil particles as rectangular blocks and the other represents soil particles as spheres. The sphere model was found to be superior.

  16. Designing of Hybrid Structured Glass Laminated Transparent Nano Composites through Vacuum infusion Technique

    NASA Astrophysics Data System (ADS)

    Mukherji, A.; Tarapure, N. D.; Wakure, G. N.

    2017-05-01

    Glass is the most commonly used transparent material. However, glass is not suitable in applications where low weight, high strength is required. The present invention comprises a method of making a Transparent Glass Laminated Nano composite product. The product contains a Bidirectionally oriented E-Glass Fabric an essentially bidirectional yarn woven fabrics is stretched Bidirectionally by specially fabricated steel frame associated with both co and counter rotating device. These fibers include glass fibrics/cloths or mixtures of any of these. The synthetic fiber may be any synthetic silica based oven waived bi-directional or Uni-directional fabrics. Engaged gear provided in the device develops uniform tension on fabric, in both direction. Nano particle dispersed resin to be used is formulated with their respective curing agents and extenders. The formulated resin contains 0.1-0.5% of Nano additives and the product composed from 5-10 % of Glass fabric, between 10 to 20 % of ordinary glass, and between 60-80 % of the product is the Nano particles dispersed formulated resin, all measured by volume.

  17. Bidirectional fiber-wireless and fiber-IVLLC integrated system based on polarization-orthogonal modulation scheme.

    PubMed

    Lu, Hai-Han; Li, Chung-Yi; Chen, Hwan-Wei; Ho, Chun-Ming; Cheng, Ming-Te; Huang, Sheng-Jhe; Yang, Zih-Yi; Lin, Xin-Yao

    2016-07-25

    A bidirectional fiber-wireless and fiber-invisible laser light communication (IVLLC) integrated system that employs polarization-orthogonal modulation scheme for hybrid cable television (CATV)/microwave (MW)/millimeter-wave (MMW)/baseband (BB) signal transmission is proposed and demonstrated. To our knowledge, it is the first one that adopts a polarization-orthogonal modulation scheme in a bidirectional fiber-wireless and fiber-IVLLC integrated system with hybrid CATV/MW/MMW/BB signal. For downlink transmission, carrier-to-noise ratio (CNR), composite second-order (CSO), composite triple-beat (CTB), and bit error rate (BER) perform well over 40-km single-mode fiber (SMF) and 10-m RF/50-m optical wireless transport scenarios. For uplink transmission, good BER performance is obtained over 40-km SMF and 50-m optical wireless transport scenario. Such a bidirectional fiber-wireless and fiber-IVLLC integrated system for hybrid CATV/MW/MMW/BB signal transmission will be an attractive alternative for providing broadband integrated services, including CATV, Internet, and telecommunication services. It is shown to be a prominent one to present the advancements for the convergence of fiber backbone and RF/optical wireless feeder.

  18. Color coded multiple access scheme for bidirectional multiuser visible light communications in smart home technologies

    NASA Astrophysics Data System (ADS)

    Tiwari, Samrat Vikramaditya; Sewaiwar, Atul; Chung, Yeon-Ho

    2015-10-01

    In optical wireless communications, multiple channel transmission is an attractive solution to enhancing capacity and system performance. A new modulation scheme called color coded multiple access (CCMA) for bidirectional multiuser visible light communications (VLC) is presented for smart home applications. The proposed scheme uses red, green and blue (RGB) light emitting diodes (LED) for downlink and phosphor based white LED (P-LED) for uplink to establish a bidirectional VLC and also employs orthogonal codes to support multiple users and devices. The downlink transmission for data user devices and smart home devices is provided using red and green colors from the RGB LEDs, respectively, while uplink transmission from both types of devices is performed using the blue color from P-LEDs. Simulations are conducted to verify the performance of the proposed scheme. It is found that the proposed bidirectional multiuser scheme is efficient in terms of data rate and performance. In addition, since the proposed scheme uses RGB signals for downlink data transmission, it provides flicker-free illumination that would lend itself to multiuser VLC system for smart home applications.

  19. Performance assessment of bi-directional knotless tissue-closure devices in juvenile Chinook salmon surgically implanted with acoustic transmitters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woodley, Christa M.; Wagner, Katie A.; Bryson, Amanda J.

    Acoustic transmitters used in survival and telemetry studies are often surgically implanted in fish. While this is a well-established method, it has the potential to affect health, behavior, and survival, thus affecting study results. Much research has been done to try to minimize the harmful effects caused by the transmitter and tagging process. In 2009, we first investigated the use of a bi-directional knotless (barbed) suture material in juvenile Chinook salmon (Oncorhynchus tshawytscha). We found that it resulted in higher tag retention than the simple interrupted suture pattern; however, the occurrence of ulceration and redness increased. The objective of thismore » study was to refine the suturing patterns of the bi-directional knotless suture and retest suture performance in juvenile Chinook salmon. We tested the bi-directional suture using 3 different suture patterns and two needle types: 6-Point (12-mm needle circumference), Wide “N” (12-mm needle circumference), Wide “N” Knot 12 (12-mm needle circumference), and Wide “N” Knot 18 (18-mm needle circumference).« less

  20. Bi-directional power control system for voltage converter

    DOEpatents

    Garrigan, Neil Richard; King, Robert Dean; Schwartz, James Edward

    1999-01-01

    A control system for a voltage converter includes: a power comparator for comparing a power signal on input terminals of the converter with a commanded power signal and producing a power comparison signal; a power regulator for transforming the power comparison signal to a commanded current signal; a current comparator for comparing the commanded current signal with a measured current signal on output terminals of the converter and producing a current comparison signal; a current regulator for transforming the current comparison signal to a pulse width modulator (PWM) duty cycle command signal; and a PWM for using the PWM duty cycle command signal to control electrical switches of the converter. The control system may further include: a command multiplier for converting a voltage signal across the output terminals of the converter to a gain signal having a value between zero (0) and unity (1), and a power multiplier for multiplying the commanded power signal by the gain signal to provide a limited commanded power signal, wherein power comparator compares the limited commanded power signal with the power signal on the input terminals.

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