Price Analysis on Commercial Item Purchases Within the Department of Defense
2013-09-01
KTR contractor MFR memorandum for record MRR market research report PBS Public Building Service SAP simplified acquisition procedures...and reasonable. The survey asked what challenges the respondents face in executing price analysis and in determining and documenting price...organization’s biggest challenge was, a split response was received. Three supervisors answered that the skill level of employees was the biggest challenge
Adaptive Management for a Turbulent Future
The challenges that face humanity today differ from the past because as the scale of human influence has increased, our biggest challenges have become global in nature, and formerly local problems that could be addressed by shifting populations or switching resources, now aggrega...
NASA Astrophysics Data System (ADS)
Durrani, Matin
2018-02-01
Yasuhiro Iye, a condensed-matter physicist who is executive director of the Japan Society for the Promotion of Science, talks to Matin Durrani about the pressures and challenges facing Japan's biggest funding agency
ERIC Educational Resources Information Center
Coley, David C.
2009-01-01
School administrators are facing the perfect storm: a growing number of baby boomers retiring each year, an absence of experienced teachers to take their place, and high turnover among young teachers. The need to hire and retain a new generation of teachers is one of the biggest challenges facing school administrators. To fill these vacancies,…
The Method of Tadabur Qur'an: What Are the Student Views?
ERIC Educational Resources Information Center
Asyafah, Abas
2014-01-01
The underlying problem facing the teaching of Islamic education across Indonesia is the inadequacy and ineffective teaching and learning methods. The teaching of Islam in the institutions of higher education is still limited to conceptualization and memorization. However, the biggest challenge the country faces is the limited research about…
Standing by Their Principles: Two Librarians Who Faced Challenges
ERIC Educational Resources Information Center
Adams, Helen; Leu, DaNae; Venuto, Dee Ann
2015-01-01
What do school librarians fear most? Hands down, their biggest fear is a formal challenge to a resource in the school library. There are no accurate statistics about the number of challenges to school library resources. The staff of ALA's Office for Intellectual Freedom estimates that only about 20 percent are reported to ALA annually. For the…
ERIC Educational Resources Information Center
Jolin, Michele; Schmitz, Paul; Seldon, Willa
2012-01-01
Communities face powerful challenges--a high-school dropout epidemic, youth unemployment, teen pregnancy--that require powerful solutions. In a climate of increasingly constrained resources, those solutions must help communities to achieve more with less. A new kind of community collaborative--an approach that aspires to significant,…
Quantitative sensing of bridges, railways, and tunnels with autonomous unmanned aerial vehicles.
DOT National Transportation Integrated Search
2017-05-04
Managing a growing population of deteriorated transportation infrastructure : systems (i.e. bridges, railways, tunnels) is one of biggest challenges faced by the nation. : Traditional inspection and monitoring techniques (e.g., visual inspection, mec...
We Should Not Give up on Kids: Interviews with former U.S. Attorney General Janet Reno.
ERIC Educational Resources Information Center
Reno, Janet
2001-01-01
In two interviews Janet Reno, former U.S. Attorney General, discusses the biggest challenges facing children and youth and how government, families, and communities can come together to meet these challenges. The first interview was conducted by Mary Shahbazian; the second was conducted by Father Chris Riley. (Author)
Reviewing education challenges and solutions for health professionals in community care.
Kirk, Mary
2015-10-01
The biggest asset of the NHS is its staff. Health professionals working in the community are faced with a number of challenges to maintain and develop their knowledge and skills in their clinical practice. NHS England's Five Year Forward View describes the need for change, identifying the necessity to reshape care delivery, harnessing technology, and driving down variations in quality and safety of care. This article explores some of the challenges faced by community health-care providers and reviews possible solutions to meet community health-care needs for now as well as the future.
Removal of Perchlorate and Chlorate in Aquatic SystemsUsing Integrated Technologies
Because of its extremely low concentrations and strong resistance to most treatment technologies, perchlorate has become one of the biggest challenges currently being faced by the drinking water industry. Few studies have looked at electrochemical reduction of aqueous perchlorate...
Pediatric PHO requires strong heart, good partner.
1997-05-01
As states convert Medicaid into managed care, pediatric PHOs must change their operating dynamics to meet the challenges and take advantage of the emerging opportunities. One of the biggest questions these PHOs face is whether to start their own HMOs and risk alienating existing payers.
ERIC Educational Resources Information Center
Tomaino, Robert
2011-01-01
This article discusses Roses for Autism, a program that provides training, guidance and employment opportunities for older students and adults on the autistic spectrum. Roses for Autism tackles one of the biggest challenges currently facing the autism community--a disproportionally high unemployment rate that hovers around 88 percent. Although a…
Transforming Cultural Trauma into Resilience
ERIC Educational Resources Information Center
Brokenleg, Martin
2012-01-01
One of the biggest challenges facing Aboriginal populations increasingly is being called "intergenerational trauma." Restoring the cultural heritage is a central theme in the book, "Reclaiming Youth at Risk." That work describes the Circle of Courage model for positive development which blends Native child and youth care…
PGT: A Statistical Approach to Prediction and Mechanism Design
NASA Astrophysics Data System (ADS)
Wolpert, David H.; Bono, James W.
One of the biggest challenges facing behavioral economics is the lack of a single theoretical framework that is capable of directly utilizing all types of behavioral data. One of the biggest challenges of game theory is the lack of a framework for making predictions and designing markets in a manner that is consistent with the axioms of decision theory. An approach in which solution concepts are distribution-valued rather than set-valued (i.e. equilibrium theory) has both capabilities. We call this approach Predictive Game Theory (or PGT). This paper outlines a general Bayesian approach to PGT. It also presents one simple example to illustrate the way in which this approach differs from equilibrium approaches in both prediction and mechanism design settings.
Popular Music Helps Students Focus on Important Social Issues
ERIC Educational Resources Information Center
Moore, James R.
2007-01-01
One of the biggest challenges facing middle school social studies educators is creating powerful lessons that engage young adolescents in acquiring knowledge, stimulate critical thinking skills, inspire passionate interest in social studies and social issues, encourage active participation in civic life, and provide them with opportunities to…
Developing Technical Skill Assessments
ERIC Educational Resources Information Center
Hyslop, Alisha
2009-01-01
One of the biggest challenges facing the career and technical education (CTE) community as it works to implement the 2006 Perkins Act is responding to more rigorous requirements for reporting on CTE students' technical skill attainment. The U.S. Department of Education suggested in non-regulatory guidance that states and locals use the number of…
Top Benefits Challenges Facing School Business Decision Makers
ERIC Educational Resources Information Center
Bohling, Joseph
2012-01-01
What's the main factor coloring employee satisfaction? Many organizations' leaders think the answer is salary, yet in reality, employee benefits packages are one of the biggest incentives an employer can offer. Educational institutions have done well in providing benefits to employees. However, with an unpredictable economic climate and a complex…
Listening to Students and Faculty: The Value to Developmental Education Leaders
ERIC Educational Resources Information Center
Clifton, Connie J.
2013-01-01
Helping students complete developmental course sequences and graduate from college is one of the biggest challenges facing community college leaders and educators. The majority of entering students need one or more developmental courses yet most of these students never finish the developmental sequence. Colleges are continuously developing new…
Understanding genetic and physiological bases of salt tolerance in almond rootstocks
USDA-ARS?s Scientific Manuscript database
One of the biggest challenges California almond growers are facing is the irrigation water quality. Due to the reduced availability of good quality water, the use of alternative/ degraded waters is inevitable. The most important consideration for the use of degraded waters is the water salt concentr...
Dance All Night: Motivation in Education
ERIC Educational Resources Information Center
Criss, Ellen
2011-01-01
One of the biggest challenges that teachers of adolescents face is the necessity to motivate them. This article begins with an overview of motivational theories and then focuses on process theory and its application in the middle school and high school classrooms. An effective teacher can create motivation in students by forming relationships with…
ERIC Educational Resources Information Center
Ainscow, Mel
2007-01-01
This special edition of the journal focuses on what is, arguably, the biggest challenge facing education systems, that of developing practices that will reach out to those learners who are failed by existing arrangements. Specifically, the papers look at ways of using the views of stakeholders in order to move schools and other centres of learning…
Teacher Assessment in Wales--The TAPS Cymru Project
ERIC Educational Resources Information Center
Jones, Bethan; Coakley, Ruth; Fenn, Lisa; Earle, Sarah; Davies, Dan
2018-01-01
Making accurate, manageable assessments of children's scientific understanding, skills and progress is one of the biggest challenges facing primary teachers. In Wales, where Statutory Assessment Tests (SATs) at age 11 were phased out in 2005, teacher assessment has been the only source of pupil attainment data in science for a much longer period…
Effect of Inclusive Education Awareness Programme on Preservice Teachers
ERIC Educational Resources Information Center
Pingle, Sudha; Garg, Indu
2015-01-01
In India, the concept of inclusive education schools is gaining importance to provide equal opportunities for education for all. Aims of schools in India has is to include students with special needs in the regular classrooms. However, biggest challenge they face is lack of awareness among teachers about inclusive education. Educationists across…
Human alterations of Earth's fresh water
Sandra Postel
2000-01-01
One of the biggest challenges society faces in this new century is figuring out how to satisfy the water demands of 8 billion people while at the same time protecting the aquatic ecosystems and ecological services that humans and all species depend upon. Since 1950, water demands worldwide have more than tripled, while the scale of our dams and reservoirs, river...
Managing the College Classroom: Perspectives from an Introvert and an Extrovert
ERIC Educational Resources Information Center
Braden, Stephen W.; Smith, Deborah N.
2006-01-01
One of the biggest challenges facing college instructors in the 21st century is classroom misbehavior. The authors propose that how one handles classroom incivility is a matter of personality type. One of the authors is an extrovert; the other an introvert. The authors discuss personality theory, general classroom management, how to identify…
ERIC Educational Resources Information Center
Odora Hoppers, Catherine A.
2015-01-01
"In a time of unacceptable global injustice, growing inequalities in the distribution of power, accelerating climate change, and unwavering racism and social exclusion, we are today facing the biggest challenges of human history" (European Conference on Intercultural Dialogue in Development Education, 2008: 1). A favourable wind is…
ERIC Educational Resources Information Center
Babin, Erin Pevey
2017-01-01
The biggest challenge facing American public schools today is increasing student achievement, and this depends on the educational system's ability to improve the quality of instruction. Principals play a key role in improving the quality of instruction on their campus through the instructional leadership practices they engage in on a daily basis.…
Using Speech Recognition Software to Improve Writing Skills
ERIC Educational Resources Information Center
Diaz, Felix
2014-01-01
Orthopedically impaired (OI) students face a formidable challenge during the writing process due to their limited or non-existing ability to use their hands to hold a pen or pencil or even to press the keys on a keyboard. While they may have a clear mental picture of what they want to write, the biggest hurdle comes well before having to tackle…
ERIC Educational Resources Information Center
Iyer, Vidya V.
2011-01-01
Despite the phenomenal growth projected for the Indian information technology (IT) industry, one of the biggest challenges it faces is the high rate of turnover in offshore supplier firms based in India (Everest Research Group 2011). According to recent estimates, turnover rates among Indian information systems (IS) professionals have been…
Making Web3D Less Scary: Toward Easy-to-Use Web3D e-Learning Content Development Tools for Educators
ERIC Educational Resources Information Center
de Byl, Penny
2009-01-01
Penny de Byl argues that one of the biggest challenges facing educators today is the integration of rich and immersive three-dimensional environments with existing teaching and learning materials. To empower educators with the ability to embrace emerging Web3D technologies, the Advanced Learning and Immersive Virtual Environment (ALIVE) research…
From nurse to marketing entrepreneur.
Aydlotte, J H
1998-03-01
An important lesson in career advancement is to be prepared for and take advantage of sudden opportunities that come your way. This risk-taking nurse went into nurse recruitment, which then opened avenues into health care marketing. She pioneered one of the largest health care advertising companies in the country and describes how she has used her new-found skills, at work and at home, to face life's biggest challenges.
ERIC Educational Resources Information Center
Pardini, Priscilla
2006-01-01
Narrowing the achievement gap between students who are native English speakers and those learning English as a second language is one of the biggest challenges facing U.S. educators. This article discusses the approaches used by the Saint Paul (Minn.) Public Schools in narrowing this achievement gap. Saint Paul (Minn.) Public Schools has one of…
Network improves rural care. Interview by Donald E. Johnson.
Smith, L V
1991-12-01
Rural institutions may face one of the biggest challenges in providing up-to-date care that keeps patients in the local facility, rather than sending them to regional centers. In the following interview with Health Care Strategic Management publisher, Donald E.L. Johnson, Lloyd V. Smith, president of St. Luke's Hospitals MeritCare, a Fargo, N.D.-based health care network, reveals an educational outreach model for cardiac care that can be emulated by other institutions.
Beyond Hammers and Nails: Mitigating and Verifying Greenhouse Gas Emissions
NASA Astrophysics Data System (ADS)
Gurney, Kevin Robert
2013-05-01
One of the biggest challenges to future international agreements on climate change is an independent, science-driven method of verifying reductions in greenhouse gas emissions (GHG) [Niederberger and Kimble, 2011]. The scientific community has thus far emphasized atmospheric measurements to assess changes in emissions. An alternative is direct measurement or estimation of fluxes at the source. Given the many challenges facing the approach that uses "top-down" atmospheric measurements and recent advances in "bottom-up" estimation methods, I challenge the current doctrine, which has the atmospheric measurement approach "validating" bottom-up, "good-faith" emissions estimation [Balter, 2012] or which holds that the use of bottom-up estimation is like "dieting without weighing oneself" [Nisbet and Weiss, 2010].
A strategy to address the nursing faculty shortage.
Ganley, Barbara J; Sheets, Ingrid
2009-07-01
This article describes one university's experience in creating a master's geriatric clinical nurse specialist-nurse educator program to address the nursing faculty shortage and the need for geriatric clinical nurse specialists. The successes and challenges are outlined, and curricular ideas that may be beneficial to other nursing programs also are presented. This program has enhanced the university's pool of clinical instructors, increased its ability to provide services to older adults, and allowed faculty to instruct and focus undergraduates in the distinctions of geriatric nursing care. The biggest challenges faced were marketing and recruitment of nurses; these challenges were addressed, and possible solutions are offered. The most immediate benefit of this program was the generation of geriatric clinical nurse specialists.
Suburban wildlife: Lessons, challenges, and opportunities
DeStefano, S.; Deblinger, R.D.; Miller, C.
2005-01-01
The United States, as well as most developed and many developing nations worldwide, is becoming increasingly urban and suburban.Although urban, suburban, and commercial development account for less than one percent to just over 20% of land use among states, 50-90% of the residents of those states can be classified as urban or suburban dwellers. The population of the U.S. as a whole has risen from being > 95% rural in the 1790s to about 80% urban-suburban today. With these changes in land use and demographic patterns come changes in values and attitudes; many urbanites and suburbanites view wildlife and nature differently than rural residents. These are among the challenges faced by wildlife biologists and natural resource managers in a rapidly urbanizing world. In 2003, we convened a symposium to discuss issues related to suburban wildlife. The papers presented in this special issue of Urban Ecosystems address the lessons learned from the early and recently rapidly expanding literature, the challenges we face today, and the opportunities that can help deal with what is one of the biggest challenges to conservation in a modernizing world. ?? 2005 Springer Science + Business Media, Inc.
Using Technology to Improve Treatment Outcomes for Children and Adolescents with Eating Disorders.
Darcy, Alison M; Lock, James
2017-01-01
Dissemination and implementation of evidence-based treatments are among the biggest challenges facing clinical psychiatry. Developing scalable evidence-based treatments is a major priority and fraught with challenges. This article describes the development of 3 technology-based innovations. It discusses the use of massive open online courses (MOOCs) and mobile applications. Three projects are presented: (1) the modification of a MOOC methodology for psychotherapy training clinicians in manualized family-based therapy (FBT) for adolescents with anorexia nervosa; (2) a modified MOOC platform for the delivery of FBT; and (3) the development of mobile applications for treatment augmentation and delivery. Copyright © 2016 Elsevier Inc. All rights reserved.
Physician leaders of medical groups face increasing challenges.
Gerbarg, Zack
2002-10-01
Physician leadership has emerged as one of the biggest challenges and opportunities for medical group success. The environment for medical groups has become increasingly complex as the result of five major factors: 1) varying reimbursement methods, 2) growth in the size of groups, 3) technology investments, 4) sale and merger of groups, and 5) regulatory and legal issues. Striking the right balance between too little or too much physician involvement in leading medical groups is a key business decision. Most large, successful businesses view investment in their leaders as critical for success. Medical groups can learn from other businesses that investment in education, coaching, and succession planning for leaders is a key to long-term success.
Smart intimation and location of faults in distribution system
NASA Astrophysics Data System (ADS)
Hari Krishna, K.; Srinivasa Rao, B.
2018-04-01
Location of faults in the distribution system is one of the most complicated problems that we are facing today. Identification of fault location and severity of fault within a short time is required to provide continuous power supply but fault identification and information transfer to the operator is the biggest challenge in the distribution network. This paper proposes a fault location method in the distribution system based on Arduino nano and GSM module with flame sensor. The main idea is to locate the fault in the distribution transformer by sensing the arc coming out from the fuse element. The biggest challenge in the distribution network is to identify the location and the severity of faults under different conditions. Well operated transmission and distribution systems will play a key role for uninterrupted power supply. Whenever fault occurs in the distribution system the time taken to locate and eliminate the fault has to be reduced. The proposed design was achieved with flame sensor and GSM module. Under faulty condition, the system will automatically send an alert message to the operator in the distribution system, about the abnormal conditions near the transformer, site code and its exact location for possible power restoration.
Laurence, Sarah; Mondloch, Catherine J
2016-03-01
Most previous research on the development of face recognition has focused on recognition of highly controlled images. One of the biggest challenges of face recognition is to identify an individual across images that capture natural variability in appearance. We created a child-friendly version of Jenkins, White, Van Montford, and Burton's sorting task (Cognition, 2011, Vol. 121, pp. 313-323) to investigate children's recognition of personally familiar and unfamiliar faces. Children between 4 and 12years of age were presented with a familiar/unfamiliar teacher's house and a pile of face photographs (nine pictures each of the teacher and another identity). Each child was asked to put all the pictures of the teacher inside the house while keeping the other identity out. Children over 6years of age showed adult-like familiar face recognition. Unfamiliar face recognition improved across the entire age range, with considerable variability in children's performance. These findings suggest that children's ability to tolerate within-person variability improves with age and support a face-space framework in which faces are represented as regions, the size of which increases with age. Copyright © 2015 Elsevier Inc. All rights reserved.
Tackling drug and alcohol misuse in Brazil: priorities and challenges for nurses.
Rassool, G H; Villar-Luis, M
2004-12-01
To provide an overview of the extent of drug and alcohol misuse in Brazil and the policies and approaches in tackling substance misuse. An examination of the challenges facing the nursing profession in working with substance misusers is presented. Alcohol, cocaine, and cannabis are the most commonly misused psychoactive substances in Brazil. One of the biggest public health problems is the interface between the misuse of psychoactive substances and HIV prevalence and other sexually transmitted diseases. Findings from a recent study suggest that undergraduate nurses in Brazil are not adequately prepared in the care and management of substance misuse problems. The nursing profession in Brazil faces numerous challenges in the development of professional competence of nurses in this field. A strategy proposed is the creation of regional centres in Brazil to study the integration of substance use and misuse in the nursing undergraduate curriculum and the giving of specific support in teaching and research to nurse teachers. Nurses have a key role to play in the early recognition, assessment, prevention, and treatment of substance misuse.
Life Extension Activities for the Hubble Space Telescope
NASA Technical Reports Server (NTRS)
Walyus, Keith D.; Pepe, Joyce A. K.; Prior, Michael
2004-01-01
With the cancellation of the Hubble Space Telescope (HST) Servicing Mission 4 (SM4), the HST Project will face numerous challenges to keep the Telescope operating during the remainder of the decade. As part of the SM4, the HST Project had planned to install various upgrades to the Telescope including the installation of new batteries and new rate integrating gyros. Without these upgrades, reliability analysis indicates that the spacecraft will lose the capability to conduct science operations later this decade. The HST team will be severely challenged to maximize the Telescope's remaining operational lifetime, while still trying to maximize - its science output and quality. Two of the biggest areas of concern are the age and condition of the batteries and gyros. Together they offer the largest potential extension in Telescope lifetime and present the biggest challenges to the HST team. The six Ni-H batteries on HST are the original batteries from launch. With fourteen years of operational life, these batteries have collectively lasted longer than any other comparable mission. Yet as with all batteries, their capacity has been declining. Engineers are examining various methods to prolong the life of these mission critical batteries, and retard the rate of degradation. This paper will focus on these and other efforts to prolong the life of the HST, thus enabling it to remain a world-class observatory for as long as possible.
Organizing a Community "Biggest Loser" Weight Loss Challenge
ERIC Educational Resources Information Center
Jensen, Kirstin D.
2013-01-01
The program described here shows how Extension can be a strong collaborative partner in a rural setting in improving the overall health of the community by organizing a three month "Biggest Loser" Weight Loss Challenge. A pre-and post-fitness assessment and bi-weekly weigh-ins were administered. Three healthy lifestyle educational…
Privacy and anonymity in the information society - challenges for the European Union.
Tsoukalas, Ioannis A; Siozos, Panagiotis D
2011-03-01
Electronic information is challenging traditional views on property and privacy. The explosion of digital data, driven by novel web applications, social networking, and mobile devices makes data security and the protection of privacy increasingly difficult. Furthermore, biometric data and radiofrequency identification applications enable correlations that are able to trace our cultural, behavioral, and emotional states. The concept of privacy in the digital realm is transformed and emerges as one of the biggest risks facing today's Information Society. In this context, the European Union (EU) policy-making procedures strive to adapt to the pace of technological advancement. The EU needs to improve the existing legal frameworks for privacy and data protection. It needs to work towards a "privacy by education" approach for the empowerment of "privacy-literate" European digital citizens.
Huwendiek, Sören; Hahn, Eckhart G; Tönshoff, Burkhard; Nikendei, Christoph
2013-01-01
Despite the increasing interest in medical education in the German-speaking countries, there is currently no information available on the challenges which medical educators face. To address this problem, we carried out a web-based survey among the members of the Association for Medical Education (Gesellschaft für medizinische Ausbildung, GMA). A comprehensive survey was carried out on the need for further qualifications, expertise and the general conditions of medical educators in Germany. As part of this study, the educators were asked to list the three main challenges which they faced and which required urgent improvement. The results were analysed by means of qualitative content analysis. The questionnaire was completed by 147 of the 373 members on the GMA mailing list (response rate: 39%). The educators named a total of 346 challenges and emphasised the following areas: limited academic recognition for engagement in teaching (53.5% of educators), insufficient institutional (31.5%) and financial support (28.4%), a curriculum in need of reform (22.8%), insufficient time for teaching assignments (18,9%), inadequate teacher competence in teaching methods (18.1%), restricted faculty development programmes (18.1%), limited networking within the institution (11.0%), lack of teaching staff (10.2%), varying preconditions of students (8.7%), insufficient recognition and promotion of medical educational research (5.5%), extensive assessment requirements (4.7%), and the lack of role models within medical education (3.2%). The medical educators found the biggest challenges which they faced to be limited academic recognition and insufficient institutional and financial support. Consequently, improvements should be implemented to address these issues.
ERIC Educational Resources Information Center
Brown, Michelle J.
2018-01-01
The Biggest Mover Program, an educational program to improve daily exercise and healthy eating was developed to address the learning needs of students with intellectual and developmental disabilities and physical challenges. The program was part of a three-part program to improve the knowledge of students, staff, and teachers through the use of…
Collaboration challenges in systematic reviews: a survey of health sciences librarians
Nicholson, Joey; McCrillis, Aileen; Williams, Jeff D.
2017-01-01
Objective: While many librarians have been asked to participate in systematic reviews with researchers, often these researchers are not familiar with the systematic review process or the appropriate role for librarians. The purpose of this study was to identify the challenges and barriers that librarians face when collaborating on systematic reviews. To take a wider view of the whole process of collaborating on systematic reviews, the authors deliberately focused on interpersonal and methodological issues other than searching itself. Methods: To characterize the biggest challenges that librarians face while collaborating on systematic review projects, we used a web-based survey. The thirteen-item survey included seventeen challenges grouped into two categories: methodological and interpersonal. Participants were required to indicate the frequency and difficulty of the challenges listed. Open-ended questions allowed survey participants to describe challenges not listed in the survey and to describe strategies used to overcome challenges. Results: Of the 17 challenges listed in the survey, 8 were reported as common by over 40% of respondents. These included methodological issues around having too broad or narrow research questions, lacking eligibility criteria, having unclear research questions, and not following established methods. The remaining challenges were interpersonal, including issues around student-led projects and the size of the research team. Of the top 8 most frequent challenges, 5 were also ranked as most difficult to handle. Open-ended responses underscored many of the challenges included in the survey and revealed several additional challenges. Conclusions: These results suggest that the most frequent and challenging issues relate to development of the research question and general communication with team members. Clear protocols for collaboration on systematic reviews, as well as a culture of mentorship, can help librarians prevent and address these challenges. PMID:28983202
Collaboration challenges in systematic reviews: a survey of health sciences librarians.
Nicholson, Joey; McCrillis, Aileen; Williams, Jeff D
2017-10-01
While many librarians have been asked to participate in systematic reviews with researchers, often these researchers are not familiar with the systematic review process or the appropriate role for librarians. The purpose of this study was to identify the challenges and barriers that librarians face when collaborating on systematic reviews. To take a wider view of the whole process of collaborating on systematic reviews, the authors deliberately focused on interpersonal and methodological issues other than searching itself. To characterize the biggest challenges that librarians face while collaborating on systematic review projects, we used a web-based survey. The thirteen-item survey included seventeen challenges grouped into two categories: methodological and interpersonal. Participants were required to indicate the frequency and difficulty of the challenges listed. Open-ended questions allowed survey participants to describe challenges not listed in the survey and to describe strategies used to overcome challenges. Of the 17 challenges listed in the survey, 8 were reported as common by over 40% of respondents. These included methodological issues around having too broad or narrow research questions, lacking eligibility criteria, having unclear research questions, and not following established methods. The remaining challenges were interpersonal, including issues around student-led projects and the size of the research team. Of the top 8 most frequent challenges, 5 were also ranked as most difficult to handle. Open-ended responses underscored many of the challenges included in the survey and revealed several additional challenges. These results suggest that the most frequent and challenging issues relate to development of the research question and general communication with team members. Clear protocols for collaboration on systematic reviews, as well as a culture of mentorship, can help librarians prevent and address these challenges.
Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions.
Tralau, Tewes; Oelgeschläger, Michael; Gürtler, Rainer; Heinemeyer, Gerhard; Herzler, Matthias; Höfer, Thomas; Itter, Heike; Kuhl, Thomas; Lange, Nikola; Lorenz, Nicole; Müller-Graf, Christine; Pabel, Ulrike; Pirow, Ralph; Ritz, Vera; Schafft, Helmut; Schneider, Heiko; Schulz, Thomas; Schumacher, David; Zellmer, Sebastian; Fleur-Böl, Gaby; Greiner, Matthias; Lahrssen-Wiederholt, Monika; Lampen, Alfonso; Luch, Andreas; Schönfelder, Gilbert; Solecki, Roland; Wittkowski, Reiner; Hensel, Andreas
2015-06-01
The advent of new testing systems and "omics"-technologies has left regulatory toxicology facing one of the biggest challenges for decades. That is the question whether and how these methods can be used for regulatory purposes. The new methods undoubtedly enable regulators to address important open questions of toxicology such as species-specific toxicity, mixture toxicity, low-dose effects, endocrine effects or nanotoxicology, while promising faster and more efficient toxicity testing with the use of less animals. Consequently, the respective assays, methods and testing strategies are subject of several research programs worldwide. On the other hand, the practical application of such tests for regulatory purposes is a matter of ongoing debate. This document summarizes key aspects of this debate in the light of the European "regulatory status quo", while elucidating new perspectives for regulatory toxicity testing.
Chhabra, H S; Sharma, S; Arora, M
2018-01-01
Online survey. To understand the prevailing scenario of the comprehensive management of spinal cord injuries (SCI) in India and in the Asian Spinal Cord Network (ASCoN) region, especially with a view to document the challenges faced and its impact. Indian Spinal Injuries Centre. A questionnaire was designed which covered various aspects of SCI management. Patients, consumers (spinal injured patients discharged since at least 1 year) and experts in SCI management from different parts of India and the ASCoN region were approached to complete the survey. Sixty patients, 66 consumers and 34 experts completed the survey. Difference of opinion was noticed among the three groups. Disposable Nelaton catheters were used by 57% consumers and 47% patients. For reusable catheter, 31% experts recommended processing with soap and running water and 45% recommended clean cotton cloth bag for storage. Pre-hospital care and community inclusion pose the biggest challenges in management of SCI. More than 75% of SCI faced problems of access and mobility in the community. Awareness about SCI, illiteracy and inadequate patient education are the most important factors hindering pre- and in-hospital care. Inadequate physical as well as vocational rehabilitation and financial barriers are thought to be the major factors hindering integration of spinal injured into mainstream society. Strong family support helped in rehabilitation. Our study brought out that SCI in India and ASCoN region face numerous challenges that affect access to almost all aspects of comprehensive management of SCI.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Flintoff, F.
With the advent of industrialisation and urbanisation, developing countries are faced with numerous problems, one of the biggest being the provision of an effective solid wastes system appropriate to their varying climates and economies. The problems facing third world countries are discussed, these include the lack of a network of district depots, inadequate automotive servicing facilities and technical expertise.
NASA Astrophysics Data System (ADS)
Bhattacharya, Atreyee
2012-11-01
Water crises are one the biggest challenges facing humanity in the 21st century. But what exactly is the nature of these crises? Scientists investigated the underlying causes driving water scarcity in 22 of the best studied cases across India, China, South America, Russia, and Australia using a quantitative technique that breaks down exhaustive case studies into measurable parameters. Srinivasan et al. show that in spite of the numerous ways in which humans interact with fresh water, each shortage or crisis is driven by one or more of eight underlying causes—which can be grouped into six “syndromes.” The authors found that just as declining natural supply can drive water shortages, so can human consumption or lack of proper policies.
Lee, Seunghwa; Lee, Jaeyoung
2016-02-19
At the beginning of the 21st century, our world is faced with a global-warming problem due to the continuous increase in carbon dioxide emission, and thus, the development of novel experimental techniques is needed. The electrochemical conversion of carbon dioxide into high-value organic compounds could be of vital importance to solve this issue. The biggest challenge has always been to develop an electrocatalyst that is chemically active and structurally stable. Herein, previous studies, recent approaches, and current points of view on the electrode structure of metal oxide composites for the advanced electrochemical conversion of carbon dioxide are reviewed. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Defense AT&L (Volume 36, Number 3, May-June 2007)
2007-06-01
following five years. What are some of the biggest challenges you’ve dealt with? Photographs by SGT André Reynolds, USA A The biggest challenge is how...director of logistics operations (right); and Lt. Col. Robert Harney, DDAA commander (left). Photograph courtesy Anniston Army Depot Public Affairs Office...better A member of the DLA Contingency Support Team in Afghanistan checks an incoming subsistence shipment.DLA photograph Defense AT&L: May-June 2007 20
Building organizational supports for research-minded practitioners.
Austin, Michael J; Dal Santo, Teresa S; Lee, Chris
2012-01-01
One of the biggest challenges facing human service organizations is the proliferation of information from inside and outside the agency that needs to be managed if it is to be of use. The concepts of tacit and explicit knowledge can inform an approach to this challenge. Tacit knowledge is stored in the minds of practitioners (often called practice wisdom) and the explicit knowledge is often found in organizational procedure manuals and educational and training materials. Building on this perspective, this analysis provides a preliminary definition of research-minded practitioners by explicating the elements of curiosity, critical reflection, and critical thinking. The organizational implications of developing a cadre of research-minded practitioners include the commitment of top management to support "link officers", evidence request services, research and development units, and service standards. The challenges include the capacity to identify/support research-minded practitioners, promote an organizational culture of evidence-informed practice, redefine staff development and training, redefine job descriptions, and specify the nature of managerial leadership. Copyright © Taylor & Francis Group, LLC
Preaching What We Practice: Teaching Ethical Decision-Making to Computer Security Professionals
NASA Astrophysics Data System (ADS)
Fleischmann, Kenneth R.
The biggest challenge facing computer security researchers and professionals is not learning how to make ethical decisions; rather it is learning how to recognize ethical decisions. All too often, technology development suffers from what Langdon Winner terms technological somnambulism - we sleepwalk through our technology design, following past precedents without a second thought, and fail to consider the perspectives of other stakeholders [1]. Computer security research and practice involves a number of opportunities for ethical decisions. For example, decisions about whether or not to automatically provide security updates involve tradeoffs related to caring versus user autonomy. Decisions about online voting include tradeoffs between convenience and security. Finally, decisions about routinely screening e-mails for spam involve tradeoffs of efficiency and privacy. It is critical that these and other decisions facing computer security researchers and professionals are confronted head on as value-laden design decisions, and that computer security researchers and professionals consider the perspectives of various stakeholders in making these decisions.
Dementia skills for all: a core competency framework for the workforce in the United Kingdom.
Tsaroucha, Anna; Benbow, Susan Mary; Kingston, Paul; Le Mesurier, Nick
2013-01-01
One of the biggest challenges facing health and social care in the United Kingdom is the projected increase in the number of older people who require dementia care. The National Dementia Strategy (Department of Health, 2009) emphasizes the critical need for a skilled workforce in all aspects of dementia care. In the West Midlands, the Strategic Health Authority commissioned a project to develop a set of generic core competencies that would guide a competency based curriculum to meet the demands for improved dementia training and education. A systematic literature search was conducted to identify relevant frameworks to assist with this work. The core competency framework produced and the methods used for the development of the framework are presented and discussed.
Online market for nursing essays bigger than ever.
Jones-Berry, Stephanie
2016-11-16
Plagiarism, or submitting unacknowledged work as your own, is by far the biggest reason nursing students face disciplinary action on preregistration nursing courses, according to an exclusive survey by Nursing Standard.
Birak, P.S.; Miller, C.T.
2008-01-01
The remediation of dense non-aqueous phase liquids (DNAPLs) in porous media continues to be one of the most challenging problems facing environmental scientists and engineers. Of all the environmentally relevant DNAPLs, tars in the subsurface at former manufactured gas plants (FMGP’s) pose one of the biggest challenges due to their complex chemical composition and tendency to alter wettability. To further our understanding of these complex materials, we consulted historic documentation to evaluate the impact of gas manufacturing on the composition and physicochemical nature of the resulting tars. In the recent literature, most work to date has been focused in a relatively narrow portion of the expected range of tar materials, which has yielded a bias toward samples of relatively low viscosity and density. In this work, we consider the dissolution and movement of tars in the subsurface, models used to predict these phenomena, and approaches used for remediation. We also explore the open issues and detail important gaps in our fundamental understanding of these extraordinarily complex systems that must be resolved to reach a mature level of understanding. PMID:19176266
Rajão, Daniela S.; Pérez, Daniel R.
2018-01-01
Influenza virus infections pose a significant threat to public health due to annual seasonal epidemics and occasional pandemics. Influenza is also associated with significant economic losses in animal production. The most effective way to prevent influenza infections is through vaccination. Current vaccine programs rely heavily on the vaccine's ability to stimulate neutralizing antibody responses to the hemagglutinin (HA) protein. One of the biggest challenges to an effective vaccination program lies on the fact that influenza viruses are ever-changing, leading to antigenic drift that results in escape from earlier immune responses. Efforts toward overcoming these challenges aim at improving the strength and/or breadth of the immune response. Novel vaccine technologies, the so-called universal vaccines, focus on stimulating better cross-protection against many or all influenza strains. However, vaccine platforms or manufacturing technologies being tested to improve vaccine efficacy are heterogeneous between different species and/or either tailored for epidemic or pandemic influenza. Here, we discuss current vaccines to protect humans and animals against influenza, highlighting challenges faced to effective and uniform novel vaccination strategies and approaches. PMID:29467737
First liver transplant in Qatar: an evolving program facing many challenges.
Khalaf, Hatem; Derballa, Moataz; Elmasry, Mohammed; Khalil, Ahmed; Yakoob, Rafie; Almohannadi, Muneera; Almaslamani, Muna; Fadhil, Riadh; Al-Kaabi, Saad; Al-Ansari, Abdulla; Almaslamani, Yousuf
2013-10-01
Beginning to do liver transplants in a developing country is challenging. We report on the first few liver transplants performed in Qatar and discuss future exceptions and challenges facing our program. The first liver transplant was performed in Qatar on December 6, 2011. Since starting the program, 4 deceased-donor liver transplants have been performed in Qatar. All recipients underwent a standard deceased-donor liver transplant procedure, which included a duct-to-duct biliary anastomosis without a veno-venous bypass. All liver transplants were performed at the Hamad Medical Corporation by a local team of surgeons without external assistance. The 4 patients were all men, with a median age of 56 years (age range, 46-63 y). Indications for liver transplant included hepatitis C cirrhosis in 2 patients, and 1 patient with hepatitis B cirrhosis with hepatocellular carcinoma, and the other patient with cryptogenic liver cirrhosis. Median amount of blood transfused was 6 units (range, 0-10 U); median time spent in the intensive care unit was 2 days (range, 2-5 d); median amount of time spent in the hospital was 10 days (range, 9-16 d). All 4 recipients have survived after a median follow-up of 438 days (range, 33-602 d) and are enjoying a healthy life, with no significant posttransplant complications. A deceased-donor liver transplant can be performed in Qatar with no external assistance. However, a severe organ shortage remains the biggest obstacle facing us. Efforts should be directed toward improving the number and quality of available deceased donors in Qatar. Meanwhile, live-donor liver transplant may be the only way for us, going forward, to prevent deaths on the waiting list.
Building a genome analysis pipeline to predict disease risk and prevent disease.
Bromberg, Y
2013-11-01
Reduced costs and increased speed and accuracy of sequencing can bring the genome-based evaluation of individual disease risk to the bedside. While past efforts have identified a number of actionable mutations, the bulk of genetic risk remains hidden in sequence data. The biggest challenge facing genomic medicine today is the development of new techniques to predict the specifics of a given human phenome (set of all expressed phenotypes) encoded by each individual variome (full set of genome variants) in the context of the given environment. Numerous tools exist for the computational identification of the functional effects of a single variant. However, the pipelines taking advantage of full genomic, exomic, transcriptomic (and other) sequences have only recently become a reality. This review looks at the building of methodologies for predicting "variome"-defined disease risk. It also discusses some of the challenges for incorporating such a pipeline into everyday medical practice. © 2013. Published by Elsevier Ltd. All rights reserved.
Wackerbarth, Sarah B; Strawser-Srinath, Jamie R; Conigliaro, Joseph C
2015-05-01
Organizations use lean principles to increase quality and decrease costs. Lean projects require an understanding of systems-wide processes and utilize interdisciplinary teams. Most lean tools are straightforward, and the biggest barrier to successful implementation is often development of the team aspect of the lean approach. The purpose of this article is to share challenges experienced by a lean team charged with improving a hospital discharge process. Reflection on the experience provides an opportunity to highlight lessons from The Team Handbook by Peter Scholtes and colleagues. To improve the likelihood that process improvement initiatives, including lean projects, will be successful, organizations should consider providing training in organizational change principles and team building. The authors' lean team learned these lessons the hard way. Despite the challenges, the team successfully implemented changes throughout the organization that have had a positive impact. Training to understand the psychology of change might have decreased the resistance faced in implementing these changes. © 2014 by the American College of Medical Quality.
The Salience and Severity of Relationship Problems among Low-Income Couples
Jackson, Grace L.; Trail, Thomas E.; Kennedy, David P.; Williamson, Hannah C.; Bradbury, Thomas N.; Karney, Benjamin R.
2015-01-01
Developing programs to support low-income married couples requires an accurate understanding of the challenges they face. To address this question, we assessed the salience and severity of relationship problems by asking 862 Black, White, and Latino newlywed spouses (N=431 couples) living in low-income neighborhoods to (a) free list their three biggest sources of disagreement in the marriage, and (b) rate the severity of the problems appearing on a standard relationship problem inventory. Comparing the two sources of information revealed that, although relational problems (e.g., communication and moods) were rated as severe on the inventory, challenges external to the relationship (e.g., children) were more salient in the free listing task. The pattern of results is robust across couples of varying race/ethnicity, parental status, and income levels. We conclude that efforts to strengthen marriages among low-income couples may be more effective if they address not only relational problems, but also couples’ external stresses by providing assistance with childcare, finances, or job training. PMID:26571196
Abbey, Antonia; Wegner, Rhiana
2015-01-01
The goals of this article are to review the major findings from alcohol administration studies that use sexual aggression proxies and to encourage additional experimental research that evaluates hypotheses about the role of alcohol in the etiology of men’s sexual aggression. Experiments allow participants to be randomly assigned to drink conditions, therefore ensuring that any differences between drinkers and nondrinkers can be attributed to their alcohol consumption. One of the biggest challenges faced by experimental researchers is the identification of valid operationalizations of key constructs. The tension between internal and external validity is particularly problematic for violence researchers because they cannot allow participants to engage in the target behavior in the laboratory. The strengths and limitations associated with written vignettes, audiotapes, videotapes, and confederate proxies for sexual aggression are described. Suggestions are made for future research to broaden the generalizability of the findings from experimental research. PMID:26048214
Strong Gravitational Lensing with LSST
NASA Astrophysics Data System (ADS)
Marshall, Philip J.; Bradac, M.; Chartas, G.; Dobler, G.; Eliasdottir, A.; Falco, E.; Fassnacht, C. D.; Jee, M. J.; Keeton, C. R.; Oguri, M.; Tyson, J. A.; LSST Strong Lensing Science Collaboration
2010-01-01
LSST will find more strong gravitational lensing events than any other survey preceding it, and will monitor them all at a cadence of a few days to a few weeks. We can expect the biggest advances in strong lensing science made with LSST to be in those areas that benefit most from the large volume, and the high accuracy multi-filter time series: studies of, and using, several thousand lensed quasars and several hundred supernovae. However, the high quality imaging will allow us to detect and measure large numbers of background galaxies multiply-imaged by galaxies, groups and clusters. In this poster we give an overview of the strong lensing science enabled by LSST, and highlight the particular associated technical challenges that will have to be faced when working with the survey.
Floods and droughts: friends or foes?
NASA Astrophysics Data System (ADS)
Prudhomme, Christel
2017-04-01
Water hazards are some of the biggest threats to lives and livelihoods globally, causing serious damages to society and infrastructure. But floods and droughts are an essential part of the hydrological regime that ensures fundamental ecosystem functions, providing natural ways to bring in nutrients, flush out pollutants and enabling soils, rivers and lakes natural biodiversity to thrive. Traditionally, floods and droughts are too often considered separately, with scientific advance in process understanding, modelling, statistical characterisation and impact assessment are often done independently, possibly delaying the development of innovative methods that could be applied to both. This talk will review some of the key characteristics of floods and droughts, highlighting differences and commonalties, losses and benefits, with the aim of identifying future key research challenges faced by both current and next generation of hydrologists.
Readying health services for climate change: a policy framework for regional development.
Bell, Erica
2011-05-01
Climate change presents the biggest threat to human health in the 21st century. However, many public health leaders feel ill equipped to face the challenges of climate change and have been unable to make climate change a priority in service development. I explore how to achieve a regionally responsive whole-of-systems approach to climate change in the key operational areas of a health service: service governance and culture, service delivery, workforce development, asset management, and financing. The relative neglect of implementation science means that policymakers need to be proactive about sourcing and developing models and processes to make health services ready for climate change. Health research funding agencies should urgently prioritize applied, regionally responsive health services research for a future of climate change.
Readying Health Services for Climate Change: A Policy Framework for Regional Development
2011-01-01
Climate change presents the biggest threat to human health in the 21st century. However, many public health leaders feel ill equipped to face the challenges of climate change and have been unable to make climate change a priority in service development. I explore how to achieve a regionally responsive whole-of-systems approach to climate change in the key operational areas of a health service: service governance and culture, service delivery, workforce development, asset management, and financing. The relative neglect of implementation science means that policymakers need to be proactive about sourcing and developing models and processes to make health services ready for climate change. Health research funding agencies should urgently prioritize applied, regionally responsive health services research for a future of climate change. PMID:21421953
[Social politics against poverty and in favor of health in Mexico].
Hamui-Sutton, Alicia; Irigoyen-Coria, Arnulfo; Gómez-Clavelina, Francisco Javier; Fernández-Ortega, Miguel Angel
2006-01-01
One of the biggest challenges that Mexico faces is to fight against the poverty. The transition of a characteristic welfare model from the government in a closed economy, to an open economy where the functions of the State are limited, has modified the modalities of the social politics against poverty. Six indispensable conditions are identified for poverty's reduction: 1. Economic development with stability in order to generate more and better jobs for poor people. 2. To improve regional economies. 3. To improve home conditions of poor people. 4. To elevate education levels (to encourage an authentic heath education). 5. To diminish catastrophic expenses for health problems. 6. Technical training for all workers. The impact of poverty over health can provide valuable elements to establish effective preventive strategies on health workers.
Science to Protect Public Health and the Environment--EPA Research Program Overview 2016-2019
This document provides an overview of EPA’s research programs within the Office of Research and Development. This critically important work is providing the science needed to address the biggest problems facing environmental science.
Emotion recognition following early psychosocial deprivation
Nelson, Charles A.; Westerlund, Alissa; McDermott, Jennifer Martin; Zeanah, Charles H.; Fox, Nathan A.
2014-01-01
We examined the ability to discriminate facial expressions among 8-year-old children who had been abandoned and placed in institutions in infancy and children with no institutional rearing (Never Institutionalized Group; NIG). Following a baseline assessment (average age=22 months), half the institutionalized children were randomly assigned to a foster care intervention (foster care group; FCG) and half to remain in the institution (care as usual group; CAUG). All three groups had a more difficult time recognizing fearful as compared to neutral expressions. However, the NIG and FCG were both better at inhibiting responses to neutral and fearful faces than the CAUG. Regarding ERPs, the P1 was biggest to angry faces for the NIG, smallest among the CAUG and intermediate for the FCG. The N170 and the P300 were biggest to fear in all groups. Although the children in foster care showed improvements in their ability to recognize fear and neutral faces, and their P1 to angry was midway between the NIG and CAUG, we observed no timing of placement effects. These findings support the view that institutional rearing leads to deficits in the ability to process facial emotion, and placement in foster care partially, although incompletely, ameliorates these deficits. PMID:23627960
2002-05-17
In this photograph, Jeff Alden (left) and Justin O'Cornor, two middle school students at Lane Middle School in Portland, Oregon are demonstrating their Earth-to-Orbit (ETO) Design Challenge project at NASA Marshall Space Flight Center (MSFC) in Huntsville, Alabama. Jeff and Justin, who are just a couple of "typical teens," have been spending their time tackling some of the same challenges NASA engineers face when designing propulsion systems at MSFC. The ETO Design Challenge is a hands-on educational program, targeted to middle school students, in which students are assigned a project engaging in related design challenges in their classrooms under the supervision of their teachers. The project is valuable because it can be used by any student and any teacher, even those without technical backgrounds. Students in 12 states: Alabama, Arkansas, California, Colorado, Illinois, Missouri, Montana, New York, Ohio, Tennessee, Virginia, and Washington, are taking part in the MSFC's Earth-to-Orbit program. NASA uses such programs to support educational excellence while participating in educational outreach programs through centers around the country. The Oregon students' teacher, Joanne Fluvog, commented, "the biggest change I've seen is in the students' motivation and their belief in their ability to think." Both Justin and Jeff said being involved in a real engineering project has made them realize that "science is cool."
2002-05-17
In this photograph, students from all over the country gathered and discussed their Earth-to-Orbit (ETO) Design Challenge project at NASA Marshall Space Flight Center in Huntsville, Alabama. These students who are just "typical teens," have been spending their time tackling some of the same challenges NASA engineers face when designing propulsion systems at MSFC. The ETO Design Challenge is a hands-on educational program, targeted to middle school students, in which students are assigned a project engaging in related design challenges in their classrooms under the supervision of their teachers. The project is valuable because it can be used by any student, and any teacher, even those without technical backgrounds. Student in 12 states: Alabama, Arkansas, California, Colorado, Illinois, Missouri, Montana, New York, Ohio, Ternessee, Virginia, and Washington, are taking part in MSFC's Earth-to-Orbit program. NASA uses such programs to support educational excellence while participating in educational outreach programs through centers around the country. One of the students' teachers, Joanne Fluvog, commented, "the biggest change I've seen is in the students' motivation and their belief in their ability to think." Justin O'Connor and Jeff Alden, students of Lane Middle School in Portland, Oregon, participated in the ETO program and said being involved in a real engineering project has made them realize that "science is cool."
Earth-to-Orbit Education Program 'Makes Science Cool'
NASA Technical Reports Server (NTRS)
2002-01-01
In this photograph, Jeff Alden (left) and Justin O'Cornor, two middle school students at Lane Middle School in Portland, Oregon are demonstrating their Earth-to-Orbit (ETO) Design Challenge project at NASA Marshall Space Flight Center (MSFC) in Huntsville, Alabama. Jeff and Justin, who are just a couple of 'typical teens,' have been spending their time tackling some of the same challenges NASA engineers face when designing propulsion systems at MSFC. The ETO Design Challenge is a hands-on educational program, targeted to middle school students, in which students are assigned a project engaging in related design challenges in their classrooms under the supervision of their teachers. The project is valuable because it can be used by any student and any teacher, even those without technical backgrounds. Students in 12 states: Alabama, Arkansas, California, Colorado, Illinois, Missouri, Montana, New York, Ohio, Tennessee, Virginia, and Washington, are taking part in the MSFC's Earth-to-Orbit program. NASA uses such programs to support educational excellence while participating in educational outreach programs through centers around the country. The Oregon students' teacher, Joanne Fluvog, commented, 'the biggest change I've seen is in the students' motivation and their belief in their ability to think.' Both Justin and Jeff said being involved in a real engineering project has made them realize that 'science is cool.'
Earth-to-Orbit Education Program 'Makes Science Cool'
NASA Technical Reports Server (NTRS)
2002-01-01
In this photograph, students from all over the country gathered and discussed their Earth-to-Orbit (ETO) Design Challenge project at NASA Marshall Space Flight Center in Huntsville, Alabama. These students who are just 'typical teens,' have been spending their time tackling some of the same challenges NASA engineers face when designing propulsion systems at MSFC. The ETO Design Challenge is a hands-on educational program, targeted to middle school students, in which students are assigned a project engaging in related design challenges in their classrooms under the supervision of their teachers. The project is valuable because it can be used by any student, and any teacher, even those without technical backgrounds. Student in 12 states: Alabama, Arkansas, California, Colorado, Illinois, Missouri, Montana, New York, Ohio, Ternessee, Virginia, and Washington, are taking part in MSFC's Earth-to-Orbit program. NASA uses such programs to support educational excellence while participating in educational outreach programs through centers around the country. One of the students' teachers, Joanne Fluvog, commented, 'the biggest change I've seen is in the students' motivation and their belief in their ability to think.' Justin O'Connor and Jeff Alden, students of Lane Middle School in Portland, Oregon, participated in the ETO program and said being involved in a real engineering project has made them realize that 'science is cool.'
A PIECE OF THE SPACE SHUTTLE CHALLENGER WASHED ASHORE AT COCOA BEACH
NASA Technical Reports Server (NTRS)
1996-01-01
A Cocoa Beach front-end loader holds a large piece of debris from the Space Shuttle orbiter Challenger after it washed ashore in Cocoa Beach near the Coconuts on the Beach restaurant and bar. Overseeing the recovery and protection of the piece is KSC criminal investigator Jan Seinkner, facing camera at center, of EG&G Florida Inc., base operations contractor. The piece, about 15 feet by 6 feet, is believed to be part of an elevon or rudder. It is one of the biggest pieces to wash ashore to date. A smaller piece was found several blocks south. NASA recovered thousands of pounds of debris from the Atlantic Ocean after the Jan. 28, 1986 accident which destroyed the Shuttle and claimed the lives of the seven crew members; about 50 percent of the orbiter remained in the ocean after search operations were suspended. Those remains are stored at Cape Canaveral Air Station, mostly in two Minutemen silos. The two newly recovered pieces will be brought to KSC's Security Patrol Headquarters on Contractor Road for examination and temporary storage.
Racial and Gender Issues with Physics in the Pacific Region
NASA Astrophysics Data System (ADS)
Aung, Than; Singh, Awnesh; Prasad, Uma
2011-09-01
This paper examines the state of physics teaching and learning in the Pacific Island nations. How have things changed in teaching physics? We believe that some of the goals and many of the challenges faced today have changed very little over the years. This paper is purely based upon the authors' experiences in teaching physics at the first-year level at the University of the South Pacific (USP). USP is a typical medium-sized teaching and research university as compared to universities internationally. In the Pacific, it is the biggest university and is effectively serving the 12 Pacific Island nations. Consequently, the findings described here should represent the overall situation for the Pacific region. Perhaps some of our results will resonate with readers in other locations as well. Worldwide, university students often find studying physics to be very challenging, and only a small fraction of them choose physics as a major for their degree or as a career. Students at USP are not an exception, and here we describe the severity of the problem.
The pitfalls of container production
Wayne Bell
2013-01-01
This paper summarizes ten of the biggest âpitfallsâ or challenges I have encountered in my experience growing southern pine seedlings in containers over the past 30 years. Learning from challenges is an important part of growing successful nursery operations.
NASA Astrophysics Data System (ADS)
Covarrubias, Ernesto E.; Eshraghi, Mohsen
2018-03-01
Aerospace, automotive, and medical industries use selective laser melting (SLM) to produce complex parts through solidifying successive layers of powder. This additive manufacturing technique has many advantages, but one of the biggest challenges facing this process is the resulting surface quality of the as-built parts. The purpose of this research was to study the surface properties of Inconel 718 alloys fabricated by SLM. The effect of build angle on the surface properties of as-built parts was investigated. Two sets of sample geometries including cube and rectangular artifacts were considered in the study. It was found that, for angles between 15° and 75°, theoretical calculations based on the "stair-step" effect were consistent with the experimental results. Downskin surfaces showed higher average roughness values compared to the upskin surfaces. No significant difference was found between the average roughness values measured from cube and rectangular test artifacts.
Stability issues pertaining large area perovskite and dye-sensitized solar cells and modules
NASA Astrophysics Data System (ADS)
Castro-Hermosa, S.; Yadav, S. K.; Vesce, L.; Guidobaldi, A.; Reale, A.; Di Carlo, A.; Brown, T. M.
2017-01-01
Perovskite and dye-sensitized solar cells are PV technologies which hold promise for PV application. Arguably, the biggest issue facing these technologies is stability. The vast majority of studies have been limited to small area laboratory cells. Moisture, oxygen, UV light, thermal and electrical stresses are leading the degradation causes. There remains a shortage of stability investigations on large area devices, in particular modules. At the module level there exist particular challenges which can be different from those at the small cell level such as encapsulation (not only of the unit cells but of interconnections and contacts), non-uniformity of the layer stacks and unit cells, reverse bias stresses, which are important to investigate for technologies that aim for industrial acceptance. Herein we present a review of stability investigations published in the literature pertaining large area perovskite and dye-sensitized solar devices fabricated both on rigid (glass) and flexible substrates.
The interaction between intellectual property and drug regulatory systems: global perspectives.
Madden, Edward A
2007-02-01
Regulatory compliance in the development, production and sale of new drugs accounts for the largest single expense in bringing a drug product to market. To justify developmental and regulatory compliance costs, drug innovators turn to the intellectual property (IP) system to provide a means for securing returns on investment. Because the drug regulatory system in most countries operates in isolation of the IP system, one of the greatest challenges facing the pharmaceutical industry is the extent to which IP rights can be managed against an independent drug regulatory system. Many regulatory bodies in developed countries have sought to ensure a compromise between the rights of generic companies and IP owners by including safeguards in the regulatory framework, such as patent linking and data protection; however, these efforts are yet to be applied in some of the biggest potential drug markets in emerging economies.
The Ionosphere's Pocket Litter: Exploiting Crowd-Sourced Observations
NASA Astrophysics Data System (ADS)
Miller, E. S.; Frissell, N. A.; Kaeppler, S. R.; Demajistre, R.; Knuth, A. A.
2015-12-01
One of the biggest challenges faced in developing and testing our understanding of the ionosphere is acquiring data that characterizes the latitudinal and longitudinal variability of the ionosphere. While there are extensive networks of ground sites that sample the vertical distribution, we have rather poor coverage over the oceans and in parts of the southern hemisphere. Our ability to validate the ionospheric models is limited by the lack of point measurements and those measurements that essentially constitute characterization of horizontal gradients. In this talk, we discuss and demonstrate the use of various types of crowd-sourced information that enables us to extend our coverage over these regions. We will discuss new sources of these data, concepts for new experiments and the use of these data in assimilative models. We note that there are new, low cost options for obtaining data that broaden the participation beyond the aeronomy/ionospheric community.
β2-Microglobulin as a potential factor for the expansion of mesenchymal stem cells
Zhu, Ying; Su, Yongping; Cheng, Tianmin; Chung, Leland W. K.
2010-01-01
Multipotent mesenchymal stem cells (MSCs) hold great promise in regenerative medicine, but one of the biggest challenges facing for their application is the ex vivo expansion to obtain enough undifferentiated cells. Fetal bovine serum (FBS), which can elicit possible contaminations of prion, virus, zoonosis or immunological reaction against xenogenic serum antigens, still remains essential to the culture formulations. There is an urgent need to identify potential factors for the undifferentiated expansion of MSCs to reduce the use of FBS or eventually replace it. A previously recognized housekeeping gene, β2-microglobulin (β2M), is demonstrated to act as a novel growth factor to stimulate the undifferentiated ex vivo expansion and preserve the pluripotency of adult MSCs from various sources. The use of β2M might have promising implications for future clinical application of MSCs. PMID:19466557
Einstein's Biggest Blunder: A Cosmic Mystery Story
Krauss, Lawrence
2018-01-11
The standard model of cosmology built up over 20 years is no longer accepted as accurate. New data suggest that most of the energy density of the universe may be contained in empty space. Remarkably, this is exactly what would be expected if Einstein's cosmological constant really exists. If it does, its origin is the biggest mystery in physics and presents huge challenges for the fundamental theories of elementary particles and fields. Krauss explains Einstein's concept and describes its possible implications.
Green IT Model for IT Departments in Gulf Cooperation Council (GCC) Organisations
ERIC Educational Resources Information Center
Albahlal, Abdulaziz
2016-01-01
Environmental problems such as climate change, pollution, non-sustainable energy, resource depletion, and recycling Information Technology (IT) devices considered the biggest glitches which are facing developed and developing countries. IT devices have become a critical issue due to the great amount of environmental damage caused by IT companies…
ERIC Educational Resources Information Center
Alberti, Sandra
2013-01-01
Over the last two years, the author has talked with thousands of educators about the Common Core State Standards, and she has realized that one of the biggest risks they currently face is full-speed implementation without an understanding of the changes that the standards require. When a new reform initiative comes around, the instinct of teachers…
Cosgrave, Catherine; Hussain, Rafat; Maple, Myfanwy
2015-10-01
This paper aims to contribute to the development of a more sustainable Australian rural community mental health workforce by comparing the findings from a literature search investigating impacting factors on retention with the experiences of community mental health service managers running services in rural Australia. Semi-structured interviews. Public health sector, rural New South Wales. Five community mental health managers, running services in rural Australia. Interviews were undertaken as a pilot for a broader qualitative study investigating factors influencing the decision to stay or leave among community mental health professionals working in rural positions. The purpose of undertaking this pilot study was to test for validity and relevance of the retention phenomena and help inform the research design for the main study. Three key retention focussed themes were identified: (i) Staffing is a persistent challenge; (ii) Small remote towns pose the biggest challenge; and (iii) The decision to stay or leave is complex and multifactorial. The findings of this pilot study support previous research and contribute to the understanding of influences on retention among health professionals working in rural community mental health services. Importantly, those who have worked for several years in rural positions hold important information through which to explore factors that impact retention in rural and remote regions. © 2015 National Rural Health Alliance Inc.
Functional Thinking for Managing Challenging Behavior
ERIC Educational Resources Information Center
Allday, R. Allan
2018-01-01
Challenging student behavior remains one of the biggest trials for classroom teachers. Understanding why a student performs a specific behavior is important in determining how to develop an intervention that targets the function of the behavior. This column focuses on how thinking functionally about behavior can help teachers understand why…
One of the biggest challenges when conducting a continental-scale assessment of streams is setting appropriate expectations for the assessed sites. The challenge occurs for 2 reasons: 1) tremendous natural environmental heterogeneity exists within a continental landscape and 2) r...
Journalism Ethics: There Is a Difference between Law and Ethics.
ERIC Educational Resources Information Center
Hossom, Kathy
1998-01-01
Covers a session from the recent meetings of the Indiana High School Press Association (IHSPA). States that students discussed ethical decisions they face in their yearbooks and newspapers, such as handling death. Finds the biggest concern is "really covering the good and bad things in the school." Gives IHSPA's 10-point Code of Ethics.…
Investigating English Language Teacher Identity Trajectories at Mid-Career
ERIC Educational Resources Information Center
Martin, David Ray
2017-01-01
One of the biggest concerns educational institutions face is helping teachers fit into and adjust to the dynamics of the ever-changing teaching environment. What often remains a mystery is how the identity trajectories of mid-career teachers have contributed to their longevity in the field. Also important today is why teachers might choose to…
Blurring the Line between Mosque and State: Public Education in the Twin Cities
ERIC Educational Resources Information Center
Kersten, Katherine
2011-01-01
Educational institutions across America face growing pressure to accommodate the religious practices of Muslim students. One of the biggest hot spots in this respect may seem unlikely--the Twin Cities of Minneapolis and St. Paul in America's heartland. In Minnesota, controversies about religious accommodations have arisen at a number of public…
Papier-Mache Animals: An Integrating Theme for Elementary Classrooms
ERIC Educational Resources Information Center
Duran, Emilio; Ballone Duran, Lena; Worch, Eric A.
2009-01-01
One of the biggest present challenges for teachers, especially in primary classrooms, is the need to address the content standards in all subject areas with the same amount of instructional time. While curriculum integration continues to be a powerful strategy to meet this challenge, teachers often find it difficult to bridge the gap between…
Integration of Emerging Learning Technologies in Secondary Schools: A Burkina Faso Case Study
ERIC Educational Resources Information Center
Zongo, Romaric R.
2016-01-01
The purpose of this dissertation was to document the perspectives and attitudes of secondary education teachers and administrators about the perceived benefits and challenges of integrating new Emerging Learning Technologies (ELTs) in the classroom. Education has become one of the biggest challenges in the African nation of Burkina Faso where…
Presentation of the 2007 Richard S. Hodes, M.D. Honor Lecture Award
DOE Office of Scientific and Technical Information (OSTI.GOV)
McNamara, L.
Perma-Fix Environmental Services, Inc. Chief Operating Officer Larry McNamara is the 2007 recipient of the distinguished Richard S. Hodes, M.D. Honor Lecture Award from the Southeast Compact Commission for Low-Level Radioactive Waste Management. This award recognizes Mr. McNamara's innovation in the commercialization of mixed waste treatment processes for the nuclear industry, and the significant role that these innovations have played solving low-level radioactive waste (LLRW) management problems in the United States with specific emphasis on low-level mixed wastes. Low-level mixed wastes (LLMW) have historically been the most difficult wastes to treat because of the specialized equipment, permits and experience neededmore » to deal with a large variety of hazardous constituents. Prior to innovations in the mixed waste treatment industry championed by Mr. McNamara, wastes were stored at generator sites around the country in regulated storage areas, at great cost, and in many cases for decades. In this paper, Mr. McNamara shares lessons he has learned over the past seven years in developing and implementing innovative waste management solutions that have helped solve one of the nation's biggest challenges. He also describes the future challenges facing the industry. (authors)« less
The first Team Haemophilia Education meeting, 2015, Amsterdam, The Netherlands.
Berntorp, Erik; Hart, Daniel; Mancuso, Maria Elisa; d'Oiron, Roseline; Perry, David; O'Mahony, Brian; Kaczmarek, Radoslaw; Crato, Miguel; Pasi, John; Miners, Alec; Carlsson, Katarina Steen; Kitchen, Steve; Boehlen, Françoise; Giangrande, Paul; Cebura, Elizabete; Uitslager, Nanda; Osooli, Mehdi; Janeckova, Daniela; Haldon, Rosie; Rivolta, Gianna Franca
2016-07-01
Haemophilia remains a complex disorder to diagnose and manage, requiring close cooperation between multidisciplinary healthcare professionals. There are still many unmet challenges in haemophilia care. The first Team Haemophilia Education (THE) meeting, held on 7-8 May 2015 in Amsterdam, The Netherlands, aimed to promote the optimal care of haemophilia patients through education of the multidisciplinary treatment team. This was achieved by reviewing the latest developments in haemophilia management, considering how these can be implemented in the clinic to improve patient care and providing a platform for networking and debate for all haemophilia treatment team members. Haemophilia treatment centres from several countries were asked to complete a premeeting online questionnaire to establish the biggest challenges that they face when managing patients. The concerns expressed were used to develop the agenda, which comprised a combination of formal presentations, case studies and informal workshops covering such topics as pharmacokinetics, laboratory assays and tailoring of treatment to individual patients. This report is a summary of the key developments in haemophilia care presented by various investigators and healthcare professionals at THE meeting 2015. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Carbon farming economics: What have we learned?
Tang, Kai; Kragt, Marit E; Hailu, Atakelty; Ma, Chunbo
2016-05-01
This study reviewed 62 economic analyses published between 1995 and 2014 on the economic impacts of policies that incentivise agricultural greenhouse (GHG) mitigation. Typically, biophysical models are used to evaluate the changes in GHG mitigation that result from landholders changing their farm and land management practices. The estimated results of biophysical models are then integrated with economic models to simulate the costs of different policy scenarios to production systems. The cost estimates vary between $3 and $130/t CO2 equivalent in 2012 US dollars, depending on the mitigation strategies, spatial locations, and policy scenarios considered. Most studies assessed the consequences of a single, rather than multiple, mitigation strategies, and few considered the co-benefits of carbon farming. These omissions could challenge the reality and robustness of the studies' results. One of the biggest challenges facing agricultural economists is to assess the full extent of the trade-offs involved in carbon farming. We need to improve our biophysical knowledge about carbon farming co-benefits, predict the economic impacts of employing multiple strategies and policy incentives, and develop the associated integrated models, to estimate the full costs and benefits of agricultural GHG mitigation to farmers and the rest of society. Copyright © 2016 Elsevier Ltd. All rights reserved.
Growth Scenarios for the City of Guangzhou, China: Transferability and Confirmability
NASA Astrophysics Data System (ADS)
Lehner, A.; Kraus, V.; Wei, C.; Steinnocher, K.
2016-09-01
This work deals with the development of urban growth scenarios and the prevision of the spatial distribution of built-up area and population for the urban area of the city of Guangzhou in China. Using freely-available data, including remotely sensed data as well as census data from the ground, expenditure of time and costs shall remain low. Guangzhou, one of the biggest cities within the Pearl River Delta, has faced an enormous economic and urban growth during the last three decades. Due to its economical and spatial characteristics it is a promising candidate for urban growth scenarios. The monitoring and prediction of urban growth comprises data of population and give them a spatial representation. The model, originally applied for the Indian city Ahmedabad, is used for urban growth scenarios. Therefore, transferability and confirmability of the model are evaluated. Challenges that may occur by transferring a model for urban growth from one region to another are discussed. With proposing the use of urban remote sensing and freely available data, urban planners shall be fitted with a comprehensible and simple tool to be able to contribute to the future challenge Smart Growth.
Adequately Addressing Pediatric Obesity: Challenges Faced by Primary Care Providers.
Shreve, Marilou; Scott, Allison; Vowell Johnson, Kelly
2017-07-01
To assess the challenges primary care providers encounter when providing counseling for pediatric patients identified as obese. A survey assessed the current challenges and barriers to the screening and treatment of pediatric obesity for providers in northwest Arkansas who provide care to families. The survey consisted of 15 Likert scale questions and 4 open-ended questions. Time, resources, comfort, and cultural issues were reported by providers as the biggest barriers in screening and the treatment of pediatric obesity. All providers reported lack of time as a barrier to providing the care needed for obese children. Cultural barriers of both the provider and client were identified as factors, which negatively affect the care and treatment of obese children. Primary care providers continue to experience challenges when addressing pediatric obesity. In this study, a lack of adequate time to address obesity was identified as the most significant current barrier and may likely be tied to physician resources. Although reimbursement for obesity is increasing, the level of reimbursement does not support the time or the resources needed to treat patients. Many providers reported their patients' cultural view of obesity influenced how they counsel their patients. Increasing providers' knowledge concerning differences in how weight is viewed or valued may assist them in the assessment and care of obese pediatric patients. The challenges identified in previous research continue to limit providers when addressing obesity. Although progress has been made regarding knowledge of guidelines, continuing effort is needed to tackle the remaining challenges. This will allow for earlier identification and intervention, resulting in improved outcomes in pediatric obesity.
ERIC Educational Resources Information Center
Gunn, Holly
2005-01-01
Although there are many news search engines on the Web, finding the news items one wants can be challenging. Choosing appropriate search terms is one of the biggest challenges. Unless one has seen the article that one is seeking, it is often difficult to select words that were used in the headline or text of the article. The limited archives of…
ERIC Educational Resources Information Center
Farisi, Mohammad Imam
2013-01-01
Today, in the era of open access to digital-based information and communication, one of the biggest challenges in higher education to realize moral education and to build academic culture and integrity is the emergence of academic dishonesty behaviors among academic members. The paper describes academic dishonesty behaviors in Distance Higher…
Exploring Tableau Vivant: An Integrated Approach to Interpretation
ERIC Educational Resources Information Center
Barnes, Natalie Selden; Brinster, Pamela Ann; Fahey, Patrick
2005-01-01
One of the biggest challenges on the horizon in education is an increased emphasis on meeting the needs of exceptional students. Historically, we have done a more than adequate job of addressing the needs of students with physical and cognitive challenges, but those students who excel are often left to their own devices (Tomlinson, 1999;…
Publishers Face Pressure from Libraries to Freeze Prices and Cut Deals
ERIC Educational Resources Information Center
Howard, Jennifer
2009-01-01
The publishers' hall at the recent Association of College and Research Libraries conference, held in Seattle in mid-March, was a study in give-and-take: how much publishers such as Elsevier and Oxford University Press will give in this lousy economy, and how much budget-strapped librarians can take. Libraries are some of the biggest customers for…
ERIC Educational Resources Information Center
Raths, David
2012-01-01
Like the Roman god Janus, whose twin faces look both forward and back, "Campus Technology" ("CT") is using the new year as an opportunity to reflect on some of the biggest IT trends and issues of 2011 and predict their fate in 2012. In the turbulent world of higher ed IT, this is no easy task--yesterday's news can easily become tomorrow's snooze.…
Discipline in the Schools. Three Decades of Public Opinion Polling. Search Series.
ERIC Educational Resources Information Center
National Education Association, Washington, DC. Research Div.
Results from a diverse selection of public opinion polls, most conducted by Gallup, taken from 1954 to 1984 reveal Americans' long-term concern about discipline in public schools. Since 1969, in every year but one, discipline has been considered the biggest problem facing schools by at least a quarter of the respondents. One in four surveyed views…
The Generation Gap: Minitel in the Face of the Internet.
ERIC Educational Resources Information Center
Gilbert, Philippe
Starting in the 1980s the online world has seen two models: the French model, Minitel, and the American model, Internet. At the end of 1995 the Minitel network was the biggest and oldest online service with 7 million users and 20,000 service providers; one year later, the Internet arrived. Tomorrow's online model will need to be: as familiar to…
TIPS (trigger an IIF paradigm shift).
Kilcup P E, Glen; Hickox, Dick; Reynaga, Adolfo
2007-04-11
New Mexico Corporate Services (NMCS) recordable injuries have been averaging 2-4 per year for the last 5 years with no statistical improvement. However, we believe all NM employees must go home incident and injury free every day and just as healthy as they came to work. In addition, we have received feedback from several sources, that indicates some employees are reluctant to report injuries. These indicators showed us that continuing our current strategies, making incremental improvement and changes, would not give us the improvement desired. We needed a paradigm shift to get everyone completely engaged in the IIF (Incident & Injury Free) culture, in order to achieve true IIF results. We formed a small (3-person) taskforce consisting of safety representatives from EHS, Site Services and CS Operations. We reviewed 5 years worth of data to determine what was injuring our people. We also decided to review all injuries, not simply those classified as recordable by OSHA standards. First we identified the types of injury information needed to get a true picture of our safety issues. We analyzed IRB (Incident Review Board) data showing us the following factors and whether any of them contributed to the injury: - Date - Incident Description - Severity - Root Cause - Type of Injury - Season - Work Group/Shift - Area - Improper evaluation of hazard - Inadequate work procedures - Incorrect Mental Model - Inadequate PPE Requirement - Failure to Follow or Unaware of PPE Requirement - Shortcut or Schedule Pressure - Last or First Day of Shift or Adjacent to Holiday - OT - Aggravate Existing Condition - Inadequate Training or Passdown - Experience in Task - Corrective Action Taken - Overall Quality of Response. Once this information was collected for all injuries in an Excel file, we graphed it several ways to help reveal trends: Shift 7 had double the injuries of shift 5. Night shift injuries were relatively high but lower than Shift 7. Shift 5 had no severe (recordable) injuries. Biggest total injury type was ergonomic. Biggest recordable injury type (58%) was cuts/lacerations. Chemical exposure and inhalations resulted in no recordables. Biggest root cause category was behavioral. Biggest behavioral root cause was "Failure to Evaluate Hazards". Biggest administrative controls root cause was "Inadequate Procedures". Biggest engineering controls root cause was "Unrecognized Workplace Hazard". Majority of injuries occurred in Spring/Summer which accounted for 86% of recordables. Response was inadequate or poor for 25% of injuries. Number of injuries by workgroup were about equal. Work area injuries were mostly in the CUB and Subfab but CUB injuries favored cuts/lacerations while Subfab favored ergonomic injuries. These learnings and gaps were used to develop our New Mexico Site Safety Action Plan for 2005. It has also been used by individual managers and supervisors in their day-to-day business meetings, activities, and communications, for a more focused IIF message and effort. [graph: see text]. Challenges are different amongst shifts. Shift culture may be stronger than workgroup culture. Work areas pose different challenges that all should be aware of and prepared for. We should prepare ourselves for challenges posed by the Spring and Summer seasons as well. We should be aware of and prepare for the different challenges and cultures characteristic of each shift. Supervisors need to spend more time in the field with their people to help them address safety issues and help make IIF a more consistent component of daily workgroup culture. Each site should analyze their data and look for their unique safety challenges. This will allow customized, focused action plans that meet the unique needs of each site.
Bognar, Cinthia Leite Frizzera Borges; Bychkovsky, Brittany L.
2016-01-01
Worldwide, there are enormous inequities in cancer control that cause poor outcomes among patients with cancer who live in low- and middle-income countries (LMICs). One of the biggest challenges that oncology faces today is how to increase patient access to expensive, but life-saving, therapies in LMICs. Access to cancer medications in LMICs is a major problem, especially in recent years, as the costs of these therapies continue to rise exponentially. One mechanism available to LMICs to improve access to cancer medications allows a country to pursue a compulsory license for a given drug. Here, we will review how the legal framework in the World Trade Organization's Trade-Related Aspects of Intellectual Property Rights Agreement and the Doha Declaration supports countries to circumvent patent laws and acquire compulsory licenses for essential medicines. We will also discuss the current and future role of compulsory licenses in oncology and how compulsory licenses may improve access to cancer drugs in LMICs. PMID:28717715
It takes a whole nation ... to create a health care system.
Curtin, Leah
2003-01-01
The biggest failure we face today is that we argue about the effects of poverty and the benefits of welfare rather than about how to sustain a reasonably cohesive and integrated community that optimizes human development for everybody. Yet that is exactly what must happen if we are to integrate our recreational, educational, health care, and health promotion systems and employment policies to create a healthier population. Care of the sick and the elderly is not a primary wealth- (or health-) producing social function; it is a derivative activity. If a society overinvests in it, it may underinvest in the real economy ... which then will not create the jobs, stability, and wealth that support the health of the population. This is not the kind of problem that the health care system alone, or any one sector of society, can actually tackle on its own. The challenge is to create real partnerships with all sectors: employers, labor leaders, educators, police, and governmental groups.
Access to capital--a growing concern.
Carlson, Donald A
2004-01-01
Access to capital over the next ten years will be one of the biggest challenges healthcare organizations will face as they strive to remain competitive and serve their communities. Meeting the growing needs for capital will require a disciplined and honest assessment of the capital sources that will be available and the best ways of positioning an organization to maximize their uses. It is incumbent on chief executive officers and other senior leaders to create a disciplined process for allocating capital and conveying how that process will be linked to the organization's strategic plan. All of the credit constituencies "buying" healthcare need to fully understand how the organization is positioning itself for future growth and success, and detailed bond marketing plans need to be implemented well before the actual sale of a new bond issue. Large and small healthcare providers will have sufficient access to capital in the future if investors believe that senior hospital executives have a credible plan and are disciplined enough to execute it.
Decision support and data warehousing tools boost competitive advantage.
Waldo, B H
1998-01-01
The ability to communicate across the care continuum is fast becoming an integral component of the successful health enterprise. As integrated delivery systems are formed and patient care delivery is restructured, health care professionals must be able to distribute, access, and evaluate information across departments and care settings. The Aberdeen Group, a computer and communications research and consulting organization, believes that "the single biggest challenge for next-generation health care providers is to improve on how they consolidate and manage information across the continuum of care. This involves building a strategic warehouse of clinical and financial information that can be shared and leveraged by health care professionals, regardless of the location or type of care setting" (Aberdeen Group, Inc., 1997). The value and importance of data and systems integration are growing. Organizations that create a strategy and implement DSS tools to provide decision-makers with the critical information they need to face the competition and maintain quality and costs will have the advantage.
NASA Astrophysics Data System (ADS)
Torres, V.; Quek, S.; Gaydecki, P.
2010-02-01
Aging and deterioration of the main functional parts in civil structures is one of the biggest problems that private and governmental institutions, dedicated to operate and maintain such structures, are facing now days. In the case of relatively old suspension bridges, problems emerge due to corrosion and break of wires in the main cables. Decisive information and a reliable monitoring and evaluation are factors of great relevance required to prevent significant or catastrophic damages caused to the structure, and more importantly, to people. The main challenge for the NDE methods of inspection arises in dealing with the steel wrapping barrier of the suspension cable, which main function is to shield, shape and hold the bundles. The following work, presents a study of a multi-Magnetoresistive sensors system aiming to support the monitoring and evaluation of suspension cables at some of its stages. Modelling, signal acquisition, signal processing, experiments and the initial phases of implementation are presented and discussed widely.
Building the Superconducting Super Collider, 1989-1993: The Problem of Project Management
NASA Astrophysics Data System (ADS)
Riordan, Michael
2011-04-01
In attempting to construct the Superconducting Super Collider, US particle physicists faced a challenge unprecedented in the history of science. The SSC was the biggest and costliest pure scientific project ever, comparable in overall scale to the Manhattan Project or the Panama Canal - an order of magnitude larger than any previous particle accelerator or collider project. Managing such an enormous endeavor involved coordinating conventional-construction, magnet-manufacturing, and detector-building efforts costing over a billion dollars apiece. Because project-management experience at this scale did not exist within the physics community, the Universities Research Association and the US Department of Energy turned to companies and individuals from the military-industrial complex, with mixed results. The absence of a strong, qualified individual to serve as Project Manager throughout the duration of the project was a major problem. I contend that these problems in its project management contributed importantly to the SSC's 1993 demise. Research supported by NSF Award No. 823296.
Application of Life Cycle Assessment on Electronic Waste Management: A Review.
Xue, Mianqiang; Xu, Zhenming
2017-04-01
Electronic waste is a rich source of both valuable materials and toxic substances. Management of electronic waste is one of the biggest challenges of current worldwide concern. As an effective and prevailing environmental management tool, life cycle assessment can evaluate the environmental performance of electronic waste management activities. Quite a few scientific literatures reporting life cycle assessment of electronic waste management with significant outcomes have been recently published. This paper reviewed the trends, characteristics, research gaps, and challenges of these studies providing detailed information for practitioners involved in electronic waste management. The results showed that life cycle assessment studies were most carried out in Europe, followed by Asia and North America. The research subject of the studies mainly includes monitors, waste printed circuit boards, mobile phones, computers, printers, batteries, toys, dishwashers, and light-emitting diodes. CML was the most widely used life cycle impact assessment method in life cycle assessment studies on electronic waste management, followed by EI99. Furthermore, 40% of the reviewed studies combined with other environmental tools, including life cycle cost, material flow analysis, multi-criteria decision analysis, emergy analysis, and hazard assessment which came to more comprehensive conclusions from different aspects. The research gaps and challenges including uneven distribution of life cycle assessment studies, life cycle impact assessment methods selection, comparison of the results, and uncertainty of the life cycle assessment studies were examined. Although life cycle assessment of electronic waste management facing challenges, their results will play more and more important role in electronic waste management practices.
Application of Life Cycle Assessment on Electronic Waste Management: A Review
NASA Astrophysics Data System (ADS)
Xue, Mianqiang; Xu, Zhenming
2017-04-01
Electronic waste is a rich source of both valuable materials and toxic substances. Management of electronic waste is one of the biggest challenges of current worldwide concern. As an effective and prevailing environmental management tool, life cycle assessment can evaluate the environmental performance of electronic waste management activities. Quite a few scientific literatures reporting life cycle assessment of electronic waste management with significant outcomes have been recently published. This paper reviewed the trends, characteristics, research gaps, and challenges of these studies providing detailed information for practitioners involved in electronic waste management. The results showed that life cycle assessment studies were most carried out in Europe, followed by Asia and North America. The research subject of the studies mainly includes monitors, waste printed circuit boards, mobile phones, computers, printers, batteries, toys, dishwashers, and light-emitting diodes. CML was the most widely used life cycle impact assessment method in life cycle assessment studies on electronic waste management, followed by EI99. Furthermore, 40% of the reviewed studies combined with other environmental tools, including life cycle cost, material flow analysis, multi-criteria decision analysis, emergy analysis, and hazard assessment which came to more comprehensive conclusions from different aspects. The research gaps and challenges including uneven distribution of life cycle assessment studies, life cycle impact assessment methods selection, comparison of the results, and uncertainty of the life cycle assessment studies were examined. Although life cycle assessment of electronic waste management facing challenges, their results will play more and more important role in electronic waste management practices.
Hampton, Kerry D; Newton, Jennifer M; Parker, Rhian; Mazza, Danielle
2016-07-01
To understand the barriers and enablers to fertility-awareness education in general practice. Most women along with their primary care practitioners - general practitioners and practice nurses - believe that women should be educated about fertility-awareness when first reporting trouble conceiving. To date, no in-depth study has examined the enablers and challenges of this type of education in general practice. A descriptive exploratory qualitative study using deductive content analysis. General practitioners (N = 11) and practice nurses (N = 20) were recruited from general practices in three socioculturally diverse areas in Victoria, Australia. Data were collected through semistructured interviews based on the 12 domains of a theoretical behaviour change framework from April-August 2012. The participants' responses were organized into themes that fall under the framework domains. The biggest barriers to fertility-awareness education in general practice were short consultations and time constraints faced by general practitioners together with a lack of patient educational materials and remuneration to support its delivery. The biggest enablers were a greater use of nurses trained in fertility-awareness in a collaborative team care arrangement with general practitioners. This study has identified several important barriers and enablers to fertility-awareness education in general practice. Translation into practice of our findings is imperative as the first step in establishing a primary care model in fertility-awareness. This would fill an important gap in the primary care of infertile women and build capacity in general practice to reduce infertility through women's enhanced fertility knowledge. © 2016 John Wiley & Sons Ltd.
Black Holes: The making of a monster
NASA Astrophysics Data System (ADS)
Mayer, Lucio
2017-04-01
The biggest black holes in the Universe were in place soon after the Big Bang. Explaining how they formed so rapidly is a daunting challenge, but the latest simulations give clues to how this may have occurred.
Applying Metabolomics to differentiate amphibian responses to multiple stressors
Introduction/Objectives/Methods One of the biggest challenges in ecological risk assessment is determining the impact of multiple stressors on individual organisms and populations in ‘real world’ scenarios. Emerging ‘omic technologies, notably, metabolomics, pr...
Face Recognition Vendor Test 2000: Evaluation Report
2001-02-16
The biggest change in the facial recognition community since the completion of the FERET program has been the introduction of facial recognition products...program and significantly lowered system costs. Today there are dozens of facial recognition systems available that have the potential to meet...inquiries from numerous government agencies on the current state of facial recognition technology prompted the DoD Counterdrug Technology Development Program
ERIC Educational Resources Information Center
Whitley, Meredith A.; Forneris, Tanya; Barker, Bryce
2015-01-01
Many community-based sport and physical activity programs take a positive youth development approach when operating in underserved communities around the world (Forneris, Whitley, & Barker, 2013). However, one of the biggest challenges for these programs is sustainability (Lindsey, 2008). The purpose of this article is to present the 3…
Work with Us | Energy Systems Integration Facility | NREL
Work With Us Work with Us Think big. Think broadly. Think boldly. Bring NREL your biggest energy , and government could work together on the most complex and important global energy challenges of our
Des Jardins, Terrisca R.
2014-01-01
Community-based health information exchanges (HIEs) and efforts to consolidate and house data are growing, given the advent of Accountable Care Organizations (ACOs) under the Affordable Care Act and other similar population health focused initiatives. The Southeast Michigan Beacon Community (SEMBC) can be looked to as one case study that offers lessons learned, insights on challenges faced and accompanying workarounds related to governance and stakeholder engagement. The SEMBC case study employs an established Data Warehouse Governance Framework to identify and explain the necessary governance and stakeholder engagement components, particularly as they relate to community-wide data sharing and data warehouses or repositories. Perhaps the biggest lesson learned through the SEMBC experience is that community-based work is hard. It requires a great deal of community leadership, collaboration and resources. SEMBC found that organizational structure and guiding principles needed to be continually revisited and nurtured in order to build the relationships and trust needed among stakeholder organizations. SEMBC also found that risks and risk mitigation tactics presented challenges and opportunities at the outset and through the duration of the three year pilot period. Other communities across the country embarking on similar efforts need to consider realistic expectations about community data sharing infrastructures and the accompanying and necessary governance and stakeholder engagement fundamentals. PMID:25848612
Cultural Dimensions of International Business
1991-09-01
gain major objectives. -In Malaysia "saving face" is very important. To avoid a problem here, Malaysian will. say "we can" to anything. Then they proceed...twenty Malaysians . For Security Assistance Negotiations at Korean Air Force HQ-- Eight U.S. and fifteen to twenty ROKAF. For negotiations at Kordin Air...unintended insults; misunderstood direction. -Most Malaysians speak excellent English. The biggest problem is usually that very few Americans are bilingual
Air quality in the megacity of São Paulo: Evolution over the last 30 years and future perspectives
NASA Astrophysics Data System (ADS)
Andrade, Maria de Fatima; Kumar, Prashant; de Freitas, Edmilson Dias; Ynoue, Rita Yuri; Martins, Jorge; Martins, Leila D.; Nogueira, Thiago; Perez-Martinez, Pedro; de Miranda, Regina Maura; Albuquerque, Taciana; Gonçalves, Fabio Luiz Teixeira; Oyama, Beatriz; Zhang, Yang
2017-06-01
We present a comprehensive review of published results from the last 30 years regarding the sources and atmospheric characteristics of particles and ozone in the Metropolitan Area of São Paulo (MASP). During the last 30 years, many efforts have been made to describe the emissions sources and to analyse the primary and secondary formation of pollutants under a process of increasing urbanisation in the metropolitan area. From the occurrence of frequent violations of air quality standards in the 1970s and 1980s (due to the uncontrolled air pollution sources) to a substantial decrease in the concentrations of the primary pollutants, many regulations have been imposed and enforced, although those concentrations do not yet conform to the World Health Organization guidelines. The greatest challenge currently faced by the São Paulo State Environmental Protection Agency and the local community is controlling secondary pollutants such as ozone and fine particles. Understanding the formation of these secondary pollutants, by experimental or modelling approaches, requires the description of the atmospheric chemical processes driven by biofuel, ethanol and biodiesel emissions. Exposure to air pollution is the cause of many injuries to human health, according to many studies performed not only in the region but also worldwide, and affects susceptible populations such as children and the elderly. The MASP is the biggest megacity in the Southern Hemisphere, and its specifics are important for other urban areas that are facing the challenge of intensive growth that puts pressure on natural resources and worsens the living conditions in urban areas. This text discusses how imposing regulations on air quality and emission sources, mainly related to the transportation sector, has affected the evolution of pollutant concentrations in the MASP.
"My biggest challenge with diabetes…"
... day we'll have salads and chicken, for protein. I was surprised to be diagnosed with diabetes, and started eating everything that wasn't good for me. But you get more conscious of what and how much you eat. Also, my mom helped me. And ...
Nanoporous Polymers Based on Liquid Crystals
Mulder, Dirk Jan; Sijbesma, Rint; Schenning, Albert
2018-01-01
In the present review, we discuss recent advances in the field of nanoporous networks based on polymerisable liquid crystals. The field has matured in the last decade, yielding polymers having 1D, 2D, and 3D channels with pore sizes on the nanometer scale. Next to the current progress, some of the future challenges are presented, with the integration of nanoporous membranes in functional devices considered as the biggest challenge. PMID:29324669
ERIC Educational Resources Information Center
Halsband, Robin; Hassel, Bryan C.
2004-01-01
One of the single biggest challenges for a charter school is securing financing for an adequate facility. While a stellar building provides no guarantee that a school will be a success, having adequate facilities that at least meet the needs of an academic program without robbing the budget can go a long way toward creating an environment…
Clinic, hospital try to fulfill vision of coordinated care with joint venture company.
2000-09-01
Coordinated Care Services Inc., a joint venture of Carle Foundation and Carle Clinic Association in Urbana, IL, shares its initial successes and ongoing challenges after one year of operation. The biggest barrier to further improvements remains insufficient information management capability.
Mitobolites: the elixir of life.
Katewa, Subhash D; Khanna, Amit; Kapahi, Pankaj
2014-07-01
One of the biggest challenges in biology is to understand how mitochondria influence aging and age-related diseases. Chin et al. (2014) reveal how a mitochondrial metabolite (mitobolite) inhibits mitochondrial ATPase and extends lifespan by mimicking dietary restriction in worms. Copyright © 2014 Elsevier Inc. All rights reserved.
Chauhan, Vivek; Galwankar, Sagar; Kumar, Raman; Raina, Sunil Kumar; Aggarwal, Praveen; Agrawal, Naman; Krishnan, S Vimal; Bhoi, Sanjeev; Kalra, O P; Soans, Santosh T; Aggarwal, Vandana; Kubendra, Mohan; Bijayraj, R; Datta, Sumana; Srivastava, R P
2017-01-01
There have been multiple incidents where doctors have been assaulted by patient relatives and hospital facilities have been vandalized. This has led to mass agitations by Physicians across India. Violence and vandalism against health-care workers (HCWs) is one of the biggest public health and patient care challenge in India. The sheer intensity of emotional hijack and the stress levels in both practicing HCWs and patient relative's needs immediate and detail attention. The suffering of HCWs who are hurt, the damage to hospital facilities and the reactionary agitation which affects patients who need care are all together doing everything to damage the delivery of health care and relationship between a doctor and a patient. This is detrimental to India where illnesses and Injuries continue to be the biggest challenge to its growth curve. The expert group set by The Academic College of Emergency Experts and The Academy of Family Physicians of India makes an effort to study this Public Health and Patient Care Challenge and provide recommendations to solve it.
Stefaniak, Katarzyna; Wróżyńska, Magdalena
2018-02-01
Protection of common natural goods is one of the greatest challenges man faces every day. Extracting and processing natural resources such as mineral deposits contributes to the transformation of the natural environment. The number of activities designed to keep balance are undertaken in accordance with the concept of integrated order. One of them is the use of comprehensive systems of tailings storage facility monitoring. Despite the monitoring, system failures still occur. The quantitative aspect of the failures illustrates both the scale of the problem and the quantitative aspect of the consequences of tailings storage facility failures. The paper presents vast possibilities provided by the global monitoring in the effective prevention of these failures. Particular attention is drawn to the potential of using multidirectional monitoring, including technical and environmental monitoring by the example of one of the world's biggest hydrotechnical constructions-Żelazny Most Tailings Storage Facility (TSF), Poland. Analysis of monitoring data allows to take preventive action against construction failures of facility dams, which can have devastating effects on human life and the natural environment.
Preserving the evolutionary potential of floras in biodiversity hotspots.
Forest, Félix; Grenyer, Richard; Rouget, Mathieu; Davies, T Jonathan; Cowling, Richard M; Faith, Daniel P; Balmford, Andrew; Manning, John C; Procheş, Serban; van der Bank, Michelle; Reeves, Gail; Hedderson, Terry A J; Savolainen, Vincent
2007-02-15
One of the biggest challenges for conservation biology is to provide conservation planners with ways to prioritize effort. Much attention has been focused on biodiversity hotspots. However, the conservation of evolutionary process is now also acknowledged as a priority in the face of global change. Phylogenetic diversity (PD) is a biodiversity index that measures the length of evolutionary pathways that connect a given set of taxa. PD therefore identifies sets of taxa that maximize the accumulation of 'feature diversity'. Recent studies, however, concluded that taxon richness is a good surrogate for PD. Here we show taxon richness to be decoupled from PD, using a biome-wide phylogenetic analysis of the flora of an undisputed biodiversity hotspot--the Cape of South Africa. We demonstrate that this decoupling has real-world importance for conservation planning. Finally, using a database of medicinal and economic plant use, we demonstrate that PD protection is the best strategy for preserving feature diversity in the Cape. We should be able to use PD to identify those key regions that maximize future options, both for the continuing evolution of life on Earth and for the benefit of society.
Personas in online health communities.
Huh, Jina; Kwon, Bum Chul; Kim, Sung-Hee; Lee, Sukwon; Choo, Jaegul; Kim, Jihoon; Choi, Min-Je; Yi, Ji Soo
2016-10-01
Many researchers and practitioners use online health communities (OHCs) to influence health behavior and provide patients with social support. One of the biggest challenges in this approach, however, is the rate of attrition. OHCs face similar problems as other social media platforms where user migration happens unless tailored content and appropriate socialization is supported. To provide tailored support for each OHC user, we developed personas in OHCs illustrating users' needs and requirements in OHC use. To develop OHC personas, we first interviewed 16 OHC users and administrators to qualitatively understand varying user needs in OHC. Based on their responses, we developed an online survey to systematically investigate OHC personas. We received 184 survey responses from OHC users, which informed their values and their OHC use patterns. We performed open coding analysis with the interview data and cluster analysis with the survey data and consolidated the analyses of the two datasets. Four personas emerged-Caretakers, Opportunists, Scientists, and Adventurers. The results inform users' interaction behavior and attitude patterns with OHCs. We discuss implications for how these personas inform OHCs in delivering personalized informational and emotional support. Copyright © 2016 Elsevier Inc. All rights reserved.
Behavior of W-SiC/SiC dual layer tiles under LHD plasma exposure
NASA Astrophysics Data System (ADS)
Mohrez, Waleed A.; Kishimoto, Hirotatsu; Kohno, Yutaka; Hirotaki, S.; Kohyama, Akira
2013-11-01
Towards the early realization of fusion power reactors, high performance first wall and plasma facing components (PFCs) are essentially required. As one of the biggest challenges for this, high heat flux component (HHFC) design and R & D has been emphasized. This report provides the high performance HHFC materials R & D status and the first plasma exposure test result from large helical device (LHD). W-SiC/SiC dual layer tiles (hereafter, W-SiC/SiC) were developed by applied NITE process. This is the realistic concept of tungsten armor with ceramic composite substrates for fusion power reactors. The dual layer tiles were fabricated and tested their survival under the LHD divertor plasma exposure (Nominally 10 MW/m2 maximum heat load for 6 s operation cycle). The microstructure evolution, including crack and pore formation, was analyzed, besides the behavior of bonding layer between tungsten and SiC/SiC was evaluated by C-scanning images of ultrasonic method and Electron probe Micro-analyzer (EPMA). Thermal analysis was conducted by finite element method, where ANSYS code release 13.0 was used.
Thalidomide‐induced teratogenesis: History and mechanisms
2015-01-01
Nearly 60 years ago thalidomide was prescribed to treat morning sickness in pregnant women. What followed was the biggest man‐made medical disaster ever, where over 10,000 children were born with a range of severe and debilitating malformations. Despite this, the drug is now used successfully to treat a range of adult conditions, including multiple myeloma and complications of leprosy. Tragically, a new generation of thalidomide damaged children has been identified in Brazil. Yet, how thalidomide caused its devastating effects in the forming embryo remains unclear. However, studies in the past few years have greatly enhanced our understanding of the molecular mechanisms the drug. This review will look at the history of the drug, and the range and type of damage the drug caused, and outline the mechanisms of action the drug uses including recent molecular advances and new findings. Some of the remaining challenges facing thalidomide biologists are also discussed. Birth Defects Research (Part C) 105:140–156, 2015. © 2015 The Authors Birth Defects Research Part C: Embryo Today: Reviews Published by Wiley Periodicals, Inc. PMID:26043938
Do the substituent effects affect conformational freedom of squalene in hopene biosynthesis?
Nowosielski, Marcin; Hoffmann, Marcin
2011-09-01
The analysis of biochemical processes is one of the main challenges for modern computational chemistry. Probably the biggest issue facing scientists in this case is the number of factors that have to be taken into account, as even those factors that do not seem to be meaningful may eventually be crucial. Such a belief led to the investigation on the substituent effects during squalene cyclization process. We focused on the formation of lanosterol ring A through squalene epoxide and an analogue process observed in bacteria, leading to the hopene formation without an intermediate oxide. Interestingly, our results indicate that, opposite of chemical intuition, a more substituted chain is more likely to adopt a conformation suitable for the cyclization process. Presumably the rational for this behavior is the presence of intermolecular CH ... π interactions between the hydrogen atoms from methyl groups and the squalene π bonds in the open-chain structure. The effect seems to have a firm impact on the hopene formation process. Calculations were performed using two different methods: MP2 and M06-2X, combined with the cc-pVDZ basis set.
The Upside of Failure: How Regional Student Groups Learn from Their Mistakes
Mishra, Tarun; Parra, R. Gonzalo; Abeel, Thomas
2014-01-01
Success is the result of planning, hard work, determination, foresight, and a little bit of luck. Unfortunately, nobody has thought to pave the road to success. Although failure can be discouraging and time-consuming, it presents incredible learning opportunities—the biggest difference between those who succeed and those who abandon their projects lies in their response to adversity. This article reviews events undertaken by the Regional Student Groups (RSGs) in India and Argentina, the problems they encountered, and what can be learned from them. RSG-India attempted to organize an online scientific meeting (also known as a virtual conference) with geographically dispersed stakeholders, a totally new concept for them. RSG-Argentina tackled the challenge of organizing a two-day symposium, their first event ever. Some of the complications they faced were easy to fix, others led to the cancellation of activities, and all of them resulted in valuable lessons. The main goal of this article is to highlight, through their experiences, the universal importance of a healthy panel of contingency plans. PMID:25101799
Smart Health - Potential and Pathways: A Survey
NASA Astrophysics Data System (ADS)
Arulananthan, C.; Hanifa, Sabibullah Mohamed
2017-08-01
Healthcare is an imperative key field of research, where individuals or groups can be engaged in the self-tracking of any kind of biological, physical, behavioral, or environmental information. In a massive health care data, the valuable information is hidden. The quantity of the available unstructured data has been expanding on an exponential scale. The newly developing Disruptive Technologies can handle many challenges that face data analysis and ability to extract valuable information via data analytics. Connected Wellness in Healthcare would retrieve patient’s physiological, pathological and behavioral parameters through sensors to perform inner workings of human body analysis. Disruptive technologies can take us from a reactive illness-driven to a proactive wellness-driven system in health care. It is need to be strive and create a smart health system towards wellness-driven instead of being illness-driven, today’s biggest problem in health care. Wellness-driven-analytics application help to promote healthiest living environment called “Smart Health”, deliver empower based quality of living. The contributions of this survey reveals and opens (touches uncovered areas) the possible doors in the line of research on smart health and its computing technologies.
Eating disorders need more experimental psychopathology.
Jansen, Anita
2016-11-01
Eating disorders are severe and disabling mental disorders. The scientific study of eating disorders has expanded dramatically over the past few decades, and provided significant understanding of eating disorders and their treatments. Those significant advances notwithstanding, there is scant knowledge about key processes that are crucial to clinical improvement. The lack of understanding mechanisms that cause, maintain and change eating disorders, currently is the biggest problem facing the science of eating disorders. It hampers the development of really effective interventions that could be fine-tuned to target the mechanisms of change and, therefore, the development of more effective treatments. It is argued here that the science of eating disorders and eating disorder treatment could benefit tremendously from pure experimental studies into its mechanisms of change, that is, experimental psychopathology (EPP). To illustrate why eating disorders need more EPP research, some key symptoms - restriction of intake, binge eating and body overvaluation - will be discussed. EPP studies challenge some generally accepted views and offer a fresh new look at key symptoms. This will, consequently, better inform eating disorder treatments. Copyright © 2016. Published by Elsevier Ltd.
Enhancing multi-step quantum state tomography by PhaseLift
NASA Astrophysics Data System (ADS)
Lu, Yiping; Zhao, Qing
2017-09-01
Multi-photon system has been studied by many groups, however the biggest challenge faced is the number of copies of an unknown state are limited and far from detecting quantum entanglement. The difficulty to prepare copies of the state is even more serious for the quantum state tomography. One possible way to solve this problem is to use adaptive quantum state tomography, which means to get a preliminary density matrix in the first step and revise it in the second step. In order to improve the performance of adaptive quantum state tomography, we develop a new distribution scheme of samples and extend it to three steps, that is to correct it once again based on the density matrix obtained in the traditional adaptive quantum state tomography. Our numerical results show that the mean square error of the reconstructed density matrix by our new method is improved to the level from 10-4 to 10-9 for several tested states. In addition, PhaseLift is also applied to reduce the required storage space of measurement operator.
Tomlinson, Alexandra J; Chambers, Mark A; McDonald, Robbie A; Delahay, Richard J
2015-01-01
Bovine tuberculosis is one of the biggest challenges facing cattle farming in Great Britain. European badgers (Meles meles) are a reservoir host for the causal agent, Mycobacterium bovis. There have been significant recent advances in diagnostic testing for tuberculosis in humans, cattle and badgers, with the development of species-specific assays for interferon-γ (IFN-γ), an important cytokine in tuberculous infections. Using data collected from longitudinal studies of naturally infected wild badgers, we report that the magnitude of the IFN-γ response to M. bovis antigens at the disclosing test event was positively correlated with subsequent progression of disease to a seropositive or excreting state. In addition, we show that the magnitude of the IFN-γ response, despite fluctuation, declined with time after the disclosing event for all badgers, but remained significantly higher in those animals with evidence of disease progression. We discuss how our findings may be related to the immunopathogenesis of natural M. bovis infection in badgers. PMID:25109384
Human Capital in Turnaround Schools
ERIC Educational Resources Information Center
Ferris, Kristen
2012-01-01
Finding, keeping and supporting great educators presents the single biggest challenge to successful school turnarounds. Without teachers and administrators who bring the needed combination of skills and passion, nothing else will achieve the desired effect. The turnaround model supported by the U.S. Department of Education School Improvement Grant…
Valuing U.S. Water Quality at Regional and National Scales
Assessing and monetizing the benefits of water quality at a regional and/or national scale is a challenging problem. One of the biggest problems is a lack of consistency in the monitoring and assessment methods used by states to assess water quality. Despite this inconsistency,...
The Governor's Challenge: "Building a Stronger Virginia Today": Transportation Visions and Solutions
NASA Technical Reports Server (NTRS)
Baker, Susan
2008-01-01
Using STM(Science, Technology, Engineering, Math) education, this emerging workforce will have the chance to creatively solve one of Virginia's biggest challenges: TRANSPORTATION. - Students will be asked to develop alternative transportation systems for the state. This competition will enable teams to work with business mentors to design creative solutions for regional gridlocks and develop other transportation systems to more easily and expediently reach all parts of the Commonwealth.
Challenges and opportunities in synthetic biology for chemical engineers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Luo, YZ; Lee, JK; Zhao, HM
Synthetic biology provides numerous great opportunities for chemical engineers in the development of new processes for large-scale production of biofuels, value-added chemicals, and protein therapeutics. However, challenges across all scales abound. In particular, the modularization and standardization of the components in a biological system, so-called biological parts, remain the biggest obstacle in synthetic biology. In this perspective, we will discuss the main challenges and opportunities in the rapidly growing synthetic biology field and the important roles that chemical engineers can play in its advancement. (C) 2012 Elsevier Ltd. All rights reserved.
Challenges and opportunities in synthetic biology for chemical engineers
Luo, Yunzi; Lee, Jung-Kul; Zhao, Huimin
2012-01-01
Synthetic biology provides numerous great opportunities for chemical engineers in the development of new processes for large-scale production of biofuels, value-added chemicals, and protein therapeutics. However, challenges across all scales abound. In particular, the modularization and standardization of the components in a biological system, so-called biological parts, remain the biggest obstacle in synthetic biology. In this perspective, we will discuss the main challenges and opportunities in the rapidly growing synthetic biology field and the important roles that chemical engineers can play in its advancement. PMID:24222925
Challenges and opportunities in synthetic biology for chemical engineers.
Luo, Yunzi; Lee, Jung-Kul; Zhao, Huimin
2013-11-15
Synthetic biology provides numerous great opportunities for chemical engineers in the development of new processes for large-scale production of biofuels, value-added chemicals, and protein therapeutics. However, challenges across all scales abound. In particular, the modularization and standardization of the components in a biological system, so-called biological parts, remain the biggest obstacle in synthetic biology. In this perspective, we will discuss the main challenges and opportunities in the rapidly growing synthetic biology field and the important roles that chemical engineers can play in its advancement.
Importance of Developing Community in Distance Education Courses
ERIC Educational Resources Information Center
Moore, Robert L.
2014-01-01
The separation of student and instructor is the core characteristic of distance education (Simonson et al., 2012, p. 28), contributing to one of the biggest challenges to distance education-attrition (Dueber & Misanchuk, 2001, p. 2). By the very nature of distance education, students are different locations from one another and their…
Inclusion of Students with Disabilities in Formal Vocational Education Programs in Ethiopia
ERIC Educational Resources Information Center
Malle, Abebe Yehualawork; Pirttimaa, Raija; Saloviita, Timo
2015-01-01
In Ethiopia, individuals with disabilities have limited access to educational and vocational training opportunities. This study investigates prevailing challenges and opportunities for the participation of students with disabilities in vocational education programs in Ethiopia. Data for the study were gathered from the five biggest regions out of…
Ferrates: Greener Oxidants with Multimodal Action in Water Treatment Technologies
One of the biggest challenges for humanity in the 21st century is easy access to purified and potable water. The presence of pathogens and toxins in water causes more than two million deaths annually, mostly among children under the age of five. Identifying and deploying effectiv...
Importing Leaders for School Turnarounds: Lessons and Opportunities
ERIC Educational Resources Information Center
Kowal, Julie; Hassel, Emily Ayscue
2011-01-01
One of the biggest challenges in education today is identifying talented candidates to successfully lead turnarounds of persistently low-achieving schools. Evidence suggests that the traditional principal pool is already stretched to capacity and cannot supply enough leaders to fix failing schools. But potentially thousands of leaders capable of…
Why Indigenous Nations Studies?
ERIC Educational Resources Information Center
Porter, Robert; Yellow Bird, Michael
2000-01-01
The development of a new Indigenous Nations Studies program at the University of Kansas is described. Success depended on a critical mass of Indigenous and non-Indigenous faculty and students that had a sense of political and social justice and understood the need for institutional change. The biggest challenge was countering the entrenched…
Kruse, Clemens Scott; Bouffard, Shelby; Dougherty, Michael; Parro, Jenna Stewart
2016-06-01
Native American communities face serious health disparities and, living in rural areas, often lack regular access to healthcare services as compared to other Americans. Since the early 1970's, telecommunication technology has been explored as a means to address the cost and quality of, as well as access to, healthcare on rural reservations. This systematic review seeks to explore the use of telemedicine in rural Native American communities using the framework of cost, quality, and access as promulgated by the Affordable Care Act of 2010 and urge additional legislation to increase its use in this vulnerable population. As a systematic literature review, this study analyzes 15 peer-reviewed articles from four databases using the themes of cost, quality, and access. The theme of access was referenced most frequently in the reviewed literature, indicating that access to healthcare may be the biggest obstacle facing widespread adoption of telemedicine programs on rural Native American reservations. The use of telemedicine mitigates the costs of healthcare, which impede access to high-quality care delivery and, in some cases, deters prospective patients from accessing healthcare at all. Telemedicine offers rural Native American communities a means of accessing healthcare without incurring high costs. With attention to reimbursement policies, educational services, technological infrastructure, and culturally competent care, telemedicine has the potential to decrease costs, increase quality, and increase access to healthcare for rural Native American patients. While challenges facing the implementation of telemedicine programs exist, there is great potential for it to improve healthcare delivery in rural Native American communities. Public policy that increases funding for programs that help to expand access to healthcare for Native Americans will improve outcomes because of the increase in access.
Learning to Cope with an Ageing Society
ERIC Educational Resources Information Center
McNair, Stephen
2009-01-01
The ageing of society is one of the biggest policy challenges of this time. Growing life expectancy and low birth rates mean that, for the fist time in human history, most people, and certainly the more prosperous social groups, will be spending a third of their lives in "retirement". This has profound social, cultural and economic…
ERIC Educational Resources Information Center
White, Heather
2007-01-01
The metamorphosis of glass when heated is a magical process to students, yet teachers are often reluctant to try it in class. The biggest challenge in working with glass in the classroom is to simplify procedures just enough to ensure student success while maintaining strict safety practices so no students are injured. Project concepts and safety…
Gender-Sensitive Education for a Better World. Background Document.
ERIC Educational Resources Information Center
Aksornkool, Namtip
Economic restructuring has severely affected the education of girls, particularly in the poorest and least developed countries where poverty is the major obstacle to education. Girls still constitute the majority of children not enrolled in school, and illiteracy among women remains one of the biggest challenges for the 21st century. Deep-rooted…
Laboratory tests to assess optimal agricultural residue traits for an abrasive weed control system
USDA-ARS?s Scientific Manuscript database
One of the biggest challenges to organic agricultural production and herbicide resistant crops in industrialized countries today is the non-chemical control of weed plants. Studies of new tools and methods for weed control have been motivated by an increased consumer demand for organic produce and c...
A Task-Centered Approach to Entrepreneurship
ERIC Educational Resources Information Center
Mendenhall, Anne; Buhanan, Caixia Wu; Suhaka, Michael; Mills, Gordon; Gibson, Gregory V.; Merrill, M. David
2006-01-01
Brigham Young University (BYU)-Hawaii has a student body of approximately 2,400 students representing 70 different countries. Almost half of this student body is international, representing many different cultures and languages. One of the biggest challenges for BYU-Hawaii is return-ability; that is, the university does not want to be a stepping…
Consumer Health Information Behavior in Public Libraries: A Mixed Methods Study
ERIC Educational Resources Information Center
Yi, Yong Jeong
2012-01-01
Previous studies indicated inadequate health literacy of American adults as one of the biggest challenges for consumer health information services provided in public libraries. Little attention, however, has been paid to public users' health literacy and health information behaviors. In order to bridge the research gap, the study aims to…
Criminal Policy Debate as an Active Learning Strategy
ERIC Educational Resources Information Center
Mellgren, Caroline; Ivert, Anna-Karin
2016-01-01
One of the biggest challenges for criminal justice educators is to deal with the strongly held opinions and preconceived notions about criminal justice issues among students. It often takes the form of students being reluctant to accept certain premises that does not comply with their own experience of the issue. The general tendency to reject…
Revisiting the Digital Divide in the Context of a "Flattening" World
ERIC Educational Resources Information Center
Subramony, Deepak Prem
2014-01-01
This article employs a variety of theoretical lenses to describe the nature and ramifications of the Digital Divide, which, the author states, continues to remain one of the biggest social challenges to confront the human race in modern times--even as technological advances, globalization, and other socioeconomic shifts are rendering digital media…
ICT Research and School Performance Feedback: A Perfect Marriage?
ERIC Educational Resources Information Center
Vanderlinde, Ruben; Hermans, Ruben; van Braak, Johan
2010-01-01
An important step towards the successful integration of Information and Communication Technology (ICT) in schools is to facilitate their capacity to develop a school based ICT policy. However, one of the biggest challenges for schools is to gather data that could help shape such policy development. In this context, ICT researchers can be very…
Alternative to Proctoring in Introductory Statistics Community College Courses
ERIC Educational Resources Information Center
Feinman, Yalena
2018-01-01
The credibility of unsupervised exams, one of the biggest challenges of e-learning, is currently maintained by proctoring. However, little has been done to determine whether expensive and inconvenient proctoring is necessary. The purpose of this quantitative study was to determine whether the use of security mechanisms, based on the taxonomy of…
ERIC Educational Resources Information Center
Robinson, Emma S. J.
2011-01-01
Psychiatric disorders such as drug addiction represent one of the biggest challenges to society. This article reviews clinical and basic science research to illustrate how developments in research methodology have enabled neuroscientists to understand more about the brain mechanisms involved in addiction biology. Treating addiction represents a…
The Use of Small Scale Aerial Photography in a Regional Agricultural Survey
NASA Technical Reports Server (NTRS)
Draeger, W. C.
1971-01-01
The feasibility of performing inventories of agricultural resources using very small scale aerial or space photography has been investigated. Results to date are encouraging on two counts: (1) the questions posed initially are being answered, and (2) it would seem that a fully operational agricultural inventory using very small scale photography is not beyond the scope of present technology. The biggest problems to be faced in establishing a functional inventory system are those concerning logistics and data handling.
HNSciCloud - Overview and technical Challenges
NASA Astrophysics Data System (ADS)
Gasthuber, Martin; Meinhard, Helge; Jones, Robert
2017-10-01
HEP is only one of many sciences with sharply increasing compute requirements that cannot be met by profiting from Moore’s law alone. Commercial clouds potentially allow for realising larger economies of scale. While some small-scale experience requiring dedicated effort has been collected, public cloud resources have not been integrated yet with the standard workflows of science organisations in their private data centres; in addition, European science has not ramped up to significant scale yet. The HELIX NEBULA Science Cloud project - HNSciCloud, partly funded by the European Commission, addresses these points. Ten organisations under CERN’s leadership, covering particle physics, bioinformatics, photon science and other sciences, have joined to procure public cloud resources as well as dedicated development efforts towards this integration. The HNSciCloud project faces the challenge to accelerate developments performed by the selected commercial providers. In order to guarantee cost efficient usage of IaaS resources across a wide range of scientific communities, the technical requirements had to be carefully constructed. With respect to current IaaS offerings, dataintensive science is the biggest challenge; other points that need to be addressed concern identity federations, network connectivity and how to match business practices of large IaaS providers with those of public research organisations. In the first section, this paper will give an overview of the project and explain the findings so far. The last section will explain the key points of the technical requirements and present first results of the experience of the procurers with the services in comparison to their’on-premise’ infrastructure.
Michel, Janet; Matlakala, Christina; English, Rene; Lessells, Richard; Newell, Marie-Louise
2013-07-19
Antiretroviral therapy (ART) roll-out is fraught with challenges, many with serious repercussions. We explored and described patient behaviour-related challenges from the perspective of health care providers from non-governmental organisations involved in ART programmes in KwaZulu-Natal, South Africa. A descriptive case study design using qualitative approach was applied during this study. Data was collected from nine key informants from the three biggest NGOs involved in ART roll-out using in-depth semi-structured interviews. Transcribing and coding for emergent themes was done by two independent reviewers. Ethical approval for the study was granted by the UNISA research ethics committee of The Faculty of Health Sciences. Written consent was obtained from directors of the three NGOs involved and individual audio taped informed consent was obtained from all study participants prior to data collection. Findings revealed six broad areas of patient behaviour challenges. These were patient behaviour related to socio-economic situation of patient (skipping of medication due to lack of food, or due to lack of transport fees), belief systems (traditional and religious), stigma (non- disclosure), sexual practices (non-acceptability of condoms, teenage pregnancies), escapism (drug and alcohol abuse) and opportunism (skipping medication in order to access disability grant, teenage pregnancies in order to access child grant). New programmes need to address patient behaviour as a complex phenomenon requiring a multi-pronged approach that also addresses social norms and institutions. In the face of continued ART scale up, this is further evidence for the need for multi-sectoral collaboration to ensure successful and sustainable ART roll-out.
Water Accounting Priorities in the American West
NASA Astrophysics Data System (ADS)
Hanak, E.
2017-12-01
In regions facing water scarcity, understanding the water balance sheet—how much there is, who has claims to it, and what is actually being "spent"—is key to effectively managing supplies to meet a wide range of societal goals. This is a common challenge across the American West, a region needing to balance the water demands of large irrigated agricultural sectors, growing urban populations, and declining aquatic ecosystems—in a context of increasingly variable, and in some cases diminishing, water supplies. Many local urban water utilities, and some irrigation water suppliers, have developed sophisticated data systems for tracking water availability and use within their systems. But there are still major gaps in essential metrics at the scale of watersheds and river basins. On the supply side, key issues include understanding groundwater availability and surface-groundwater interactions. On the demand side, the biggest challenges relate to understanding groundwater use and return flows—the water that is returned to rivers or aquifers and is available for reuse. In addition, most states lack consistent accounting and data standards for sharing water availability, claims, and use information—and transparent systems for reporting information to users in ways that facilitates oversight and flexible tools such as water trading. Drawing on a detailed study of water accounting in 12 western states and 2 countries with similar water challenges (Escriva Bou et al. 2016, Accounting for Water in Dry Regions: A Comparative Review, Public Policy Institute of California), this talk provides insights on best practices that can help fill critical water accounting gaps.
The new risk paradigm for chemical process security and safety.
Moore, David A
2004-11-11
The world of safety and security in the chemical process industries has certainly changed since 11 September, but the biggest challenges may be yet to come. This paper will explain that there is a new risk management paradigm for chemical security, discuss the differences in interpreting this risk versus accidental risk, and identify the challenges we can anticipate will occur in the future on this issue. Companies need to be ready to manage the new chemical security responsibilities and to exceed the expectations of the public and regulators. This paper will outline the challenge and a suggested course of action.
Collaborative Enquiry through the Tabletop for Second/Foreign Language Learners
ERIC Educational Resources Information Center
Lin, Mei; Preston, Anne; Kharrufa, Ahmed; Kong, Zhuoran
2014-01-01
Interactional communicative competence and higher-order thinking have been well documented as two of the biggest challenges for second/foreign language learners (EFL learners). This paper evaluates the use of digital tabletops as tools for problem-solving tasks in groups. The evaluation is based on a preliminary study of an application of the use…
Knowing Their Place: Feminist Understandings and Perceptions of Women Adult Educators in Museums
ERIC Educational Resources Information Center
Clover, Darlene E.; Sanford, K.
2016-01-01
Arguing gender inequity remains one of the biggest challenges of our time, and framed within the concept of "pedagogic contact zones", our article shares findings from a five-year feminist, cross-national study of women adult educators and community practitioners in public museums and art galleries in Canada and the United Kingdom.…
Using an Epistemic Game to Facilitate Students' Problem-Solving: The Case of Hospitality Management
ERIC Educational Resources Information Center
Wang, Shwu-Huey; Wang, Hsiu-Yuan
2017-01-01
Hospitality students are required to be able to address challenging cases or problems in the work environment. However, traditional lecture- or exam-based instruction leaves a gap between theory and practice. On the other hand, modern youth live and socialise in an increasingly digital environment, and one of their biggest pastimes is playing…
ERIC Educational Resources Information Center
Harpur, Paul; Loudoun, Rebecca
2011-01-01
One of the biggest challenges confronting university students with print disabilities, such as blindness, is accessing the written word. In the past it was necessary to read text books onto cassette tape or turn them to Braille so these students could access the text books. Technological advances are making university life increasingly accessible…
The Perils of Bureaucratic Complexity: Education for All in Nigeria
ERIC Educational Resources Information Center
Bolaji, Stephen Dele; Campbell-Evans, Glenda; Gray, Jan Rosemary
2017-01-01
This paper reports research which investigated the issue of access in the Universal Basic Education (UBE) and sought to know why access to education remains the biggest challenge with over 10.5 million school-aged children out of school in Nigeria (NUT, 2004; UBEC, 2004; UNICEF Report, 2015). Data for this study were collected through document…
ERIC Educational Resources Information Center
Polavaram, Sridevi
2016-01-01
Neuroscience can greatly benefit from using novel methods in computer science and informatics, which enable knowledge discovery in unexpected ways. Currently one of the biggest challenges in Neuroscience is to map the functional circuitry of the brain. The applications of this goal range from understanding structural reorganization of neurons to…
ERIC Educational Resources Information Center
Hall Giesinger, C.; Adams Becker, S.; Davis, A.; Shedd, L.
2016-01-01
Higher education is ripe for innovation. While emerging technological developments such as digital courseware and mobiles apps have made it easier than ever for people to engage with learning resources, significant issues of access and equity persist among students from low-income, minority, single-parent families, and other disadvantaged groups.…
USDA-ARS?s Scientific Manuscript database
One of the biggest challenges to successfully phytoremediate contaminated mine land soils is the identification of plant materials that possess a broad adaptation to ecological sites and either exclude or uptake heavy metals of interest. This study evaluted forage concentrations (mg kg-1 DM) of arse...
An Exploration into Improving Examinees' Acceptance of Participation in an Online Exam
ERIC Educational Resources Information Center
Liu, I-Fan; Chen, Ruey-Shin; Lu, Hao-Chun
2015-01-01
With the rapid development of the Internet and information technology, the issues related to online exams have become the concern of an increasing number of researchers. At present, the biggest challenges for the integration of web communication technology into online exams are the ability to detect cheating behaviors during the exam, and the…
Collaborating with Parents of Students with Disabilities
ERIC Educational Resources Information Center
Cianca, Marie; Wischnowski, Michael
2012-01-01
Many Hollywood films show the struggles of students with disabilities. More often than not, the struggle involves a clash between family and school. Real life shows that the movies have some of it right. According to MetLife's 2005 Survey of the American Teacher, new teachers often consider working with parents to be their biggest challenge. Both…
CD-ROM Technology: A Manual for Librarians and Educators.
ERIC Educational Resources Information Center
Mambretti, Catherine
The maturity of CD-ROM technology now shows a dramatic change in the way librarians and teachers do their jobs. Among their biggest challenges are deciding on equipment requirements and managing the disk collection. This manual is a step-by-step guide to making the most of CD-ROM technology in schools and libraries--from the acquisition of…
ERIC Educational Resources Information Center
Sanders, Justin; Ishikura, Yukiko
2018-01-01
In 2011, the Japanese government, in partnership with the International Baccalaureate (IB) Organization, embarked on an ambitious agenda of increasing the number of schools offering the IB Diploma Programme (DP) in Japan. One of the biggest challenges in this initiative is improving the recognition of the IB Diploma as an acceptable and sought…
Schools for the Twenty-First Century: School Design and Educational Transformation
ERIC Educational Resources Information Center
Leiringer, Roine; Cardellino, Paula
2011-01-01
The Building Schools for the Future programme has been established to ensure that English secondary schools are designed or redesigned to allow for educational transformation. The programme represents the biggest single UK government investment in school buildings for over 50 years. For this reason, it poses a major challenge to those involved in…
Nitrate concentrations under irrigated agriculture
Zaporozec, A.
1983-01-01
In recent years, considerable interest has been expressed in the nitrate content of water supplies. The most notable toxic effect of nitrate is infant methemoglobinemia. The risk of this disease increases significantly at nitrate-nitrogen levels exceeding 10 mg/l. For this reason, this concentration has been established as a limit for drinking water in many countries. In natural waters, nitrate is a minor ionic constituent and seldom accounts for more than a few percent of the total anions. However, nitrate in a significant concentration may occur in the vicinity of some point sources such as septic tanks, manure pits, and waste-disposal sites. Non-point sources contributing to groundwater pollution are numerous and a majority of them are related to agricultural activities. The largest single anthropogenic input of nitrate into the groundwater is fertilizer. Even though it has not been proven that nitrogen fertilizers are responsible for much of nitrate pollution, they are generally recognized as the main threat to groundwater quality, especially when inefficiently applied to irrigated fields on sandy soils. The biggest challenge facing today's agriculture is to maintain the balance between the enhancement of crop productivity and the risk of groundwater pollution. ?? 1982 Springer-Verlag New York Inc.
Practice management: observations, issues, and empirical evidence.
Wong, H M; Braithwaite, J
2001-02-01
The primary objective of this study is to provide objective, empirical, evidence-based practice management information. This is a hitherto under-researched area of considerable interest for both the practitioner and educator. A questionnaire eliciting a mix of structured and free text responses was administered to a random sample of 480 practitioners who are members of the American Academy of Periodontology. Potential respondents not in private practice were excluded and the next listed person substituted. The results provide demographic and descriptive information about some of the main issues and problems facing practice managers, central to which are information technology (IT), financial, people management, and marketing. Human resource and marketing management appear to represent the biggest challenges. Periodontists running practices would prefer more information, development, and support in dealing with IT, finance, marketing, and people management. The empirical evidence reported here suggests that although tailored educational programs on key management issues at both undergraduate and postgraduate levels have become ubiquitous, nevertheless some respondents seek further training opportunities. Evidence-based practice management information will be invaluable to the clinician considering strategic and marketing planning, and also for those responsible for the design and conduct of predoctoral and postdoctoral programs.
New product development: A batik multifunctional chair
NASA Astrophysics Data System (ADS)
Indrawati, Sri; Sukmaningsih, Nias
2017-11-01
The biggest challenge facing by Batik industry in ASEAN Economic Community (AEC) era is the greater number of fashion competitors both domestically and internationally. Based on that condition, the development of new product variants by considering product performance and price is needed. This research was conducted to develop batik products with a new target market. Products that being developed is batik multifunctional chair using integrated value engineering and analytic hierarchy process methods. This research has been done in several stages, ie. Information stage, creative stage, value analysis and product prototyping. The results of this research shows that the batik multifunctional chair product criteria are aesthetic (29%), multifunctional (34%) and ergonomic (37%). There are three new product design alternatives that successfully being developed. Based on value analysis, the product design alternatives that have the highest value is alternative design 2, the value is 2,37. The production cost for this design is Rp. 500.000,-. Alternative design 2 specification are using Mahoni wood, Batik parang rusak pattern with natural coloring process, can be used as table and fit with customer's body anthropometry. Then a batik multifunctional chair prototype is developed based on the best alternative design.
Implementation of a participatory management model: analysis from a political perspective.
Bernardes, Andrea; G Cummings, Greta; Gabriel, Carmen Silvia; Martinez Évora, Yolanda Dora; Gomes Maziero, Vanessa; Coleman-Miller, Glenda
2015-10-01
To analyse experiences of managers and nursing staff in the implementation of participatory management, specifically processes of decision-making, communication and power in a Canadian hospital. Implementing a Participatory Management Model involves change because it is focused on the needs of patients and encourages decentralisation of power and shared decisions. The study design is qualitative using observational sessions and content analysis for data analysis. We used Bolman and Deal's four-frame theoretical framework to interpret our findings. Participatory management led to advances in care, because it allowed for more dialogue and shared decision making. However, the biggest challenge has been that all major changes are still being decided centrally by the provincial executive board. Managers and directors are facing difficulties related to this change process, such as the resistance to change by some employees and limited input to decision-making affecting their areas of responsibility; however, they and their teams are working to utilise the values and principles underlying participatory management in their daily work practices. Innovative management models encourage accountability, increased motivation and satisfaction of nursing staff, and improve the quality of care. © 2014 John Wiley & Sons Ltd.
Knowledge and Attitude of Dental Professionals of North India Toward Plagiarism
Singh, Harkanwal Preet; Guram, Namrata
2014-01-01
Background: Plagiarism is stealing of some others work or idea without proper citation. It is one of the biggest challenges faced by the scholarly world and by far a grim form of delinquency in academics. Aim: The study was designed to explore the knowledge and attitudes of dental professionals toward plagiarism. Materials and Methods: A questionnaire having 14 questions was sent either via e-mails or by sending printed copies to 5000 dental professionals, while maintaining anonymity of all the participants. Result: Most of the dental professionals know about plagiarism, and they believe that plagiarism cannot be avoided successfully. Pressure to publish was a major reason along with several others, which accounts for more and more indulgence in plagiarism. At the same time lack of facilities in private institutions and lack of funding for research work were the major factors as well, which hinder in creating research environment and hence promotes plagiarism and false studies to publish it. Conclusion: Plagiarism is present in dental professionals and that significant reduction can only be brought by awareness, objective check methods and stringent punishment. Plagiarism and other forms of academic misconduct must be recognized and must not be tolerated. PMID:24678470
Knowledge and attitude of dental professionals of north India toward plagiarism.
Singh, Harkanwal Preet; Guram, Namrata
2014-01-01
Plagiarism is stealing of some others work or idea without proper citation. It is one of the biggest challenges faced by the scholarly world and by far a grim form of delinquency in academics. The study was designed to explore the knowledge and attitudes of dental professionals toward plagiarism. A questionnaire having 14 questions was sent either via e-mails or by sending printed copies to 5000 dental professionals, while maintaining anonymity of all the participants. Most of the dental professionals know about plagiarism, and they believe that plagiarism cannot be avoided successfully. Pressure to publish was a major reason along with several others, which accounts for more and more indulgence in plagiarism. At the same time lack of facilities in private institutions and lack of funding for research work were the major factors as well, which hinder in creating research environment and hence promotes plagiarism and false studies to publish it. Plagiarism is present in dental professionals and that significant reduction can only be brought by awareness, objective check methods and stringent punishment. Plagiarism and other forms of academic misconduct must be recognized and must not be tolerated.
Meeting the challenge of finding resources for ophthalmic nurses on the World Wide Web.
Duffel, P G
1998-12-01
The World Wide Web ("the Web") is a macrocosm of resources that can be overwhelming. Often the sheer volume of material available causes one to give up in despair before finding information of any use. The Web is such a popular resource that it cannot be ignored. Two of the biggest challenges to finding good information on the Web are knowing where to start and judging whether the information gathered is pertinent and credible. This article addresses these two challenges and introduces the reader to a variety of ophthalmology and vision science resources on the World Wide Web.
Mocarski, Richard; Bissell, Kimberly
2016-01-01
Through a critical rhetorical analysis using Bandura's social cognitive theory as a lens to view The Biggest Loser (TBL), this article illustrates the contradictions between the show's health promotional aims and its entertainment aims, which show the problems the show creates for health promotion practitioners working on obesity. The social cognitive theory constructs of observational learning, psychological determinants, and environmental determinants emerged from this reading of TBL as central to how the show masquerades as a health promotion tool. This reading reveals that TBL promotes a neoliberal construction of health and obesity that challenges the worldview that many health promotion campaigns take and, therefore, complicates our own efforts to combat obesity. With this revealed, it is suggested that TBL be incorporated into health promotion campaigns only as a foil. © 2015 Society for Public Health Education.
Extracting meaning from astronomical telegrams
NASA Astrophysics Data System (ADS)
Graham, Matthew; Conwill, L.; Djorgovski, S. G.; Mahabal, A.; Donalek, C.; Drake, A.
2011-01-01
The rapidly emerging field of time domain astronomy is one of the most exciting and vibrant new research frontiers, ranging in scientific scope from studies of the Solar System to extreme relativistic astrophysics and cosmology. It is being enabled by a new generation of large synoptic digital sky surveys - LSST, PanStarrs, CRTS - that cover large areas of sky repeatedly, looking for transient objects and phenomena. One of the biggest challenges facing these is the automated classification of transient events, a process that needs machine-processible astronomical knowledge. Semantic technologies enable the formal representation of concepts and relations within a particular domain. ATELs (http://www.astronomerstelegram.org) are a commonly-used means for reporting and commenting upon new astronomical observations of transient sources (supernovae, stellar outbursts, blazar flares, etc). However, they are loose and unstructured and employ scientific natural language for description: this makes automated processing of them - a necessity within the next decade with petascale data rates - a challenge. Nevertheless they represent a potentially rich corpus of information that could lead to new and valuable insights into transient phenomena. This project lies in the cutting-edge field of astrosemantics, a branch of astroinformatics, which applies semantic technologies to astronomy. The ATELs have been used to develop an appropriate concept scheme - a representation of the information they contain - for transient astronomy using aspects of natural language processing. We demonstrate that it is possible to infer the subject of an ATEL from the vocabulary used and to identify previously unassociated reports.
Lessons Learned from Daily Uplink Operations during the Deep Impact Mission
NASA Technical Reports Server (NTRS)
Stehly, Joseph S.
2006-01-01
The daily preparation of uplink products (commands and files) for Deep Impact was as problematic as the final encounter images were spectacular. The operations team was faced with many challenges during the six-month mission to comet Tempel One of the biggest difficulties was that the Deep Impact Flyby and Impactor vehicles necessitated a high volume of uplink products while also utilizing a new uplink file transfer capability. The Jet Propulsion Laboratory (JPL) Multi-Mission Ground Systems and Services (MGSS) Mission Planning and Sequence Team (MPST) had the responsibility of preparing the uplink products for use on the two spacecraft. These responsibilities included processing nearly 15,000 flight products, modeling the states of the spacecraft during all activities for subsystem review, and ensuring that the proper commands and files were uplinked to the spacecraft. To guarantee this transpired and the health and safety of the two spacecraft were not jeopardized several new ground scripts and procedures were developed while the Deep Impact Flyby and Impactor spacecraft were en route to their encounter with Tempel-1. These scripts underwent several adaptations throughout the entire mission up until three days before the separation of the Flyby and Impactor vehicles. The problems presented by Deep Impact's daily operations and the development of scripts and procedures to ease those challenges resulted in several valuable lessons learned. These lessons are now being integrated into the design of current and future MGSS missions at JPL.
ERIC Educational Resources Information Center
Gerard, Joseph G.
2012-01-01
Getting students to network with one another can be one of the biggest challenges in college courses, despite being a highly important function of higher education. Networking can, in fact, lead to that first job or to professional advancement, and technology can improve the success of individual and institutional efforts. This article describes…
The Effectiveness of Hypochlorous Acid Solution on Healing of Infected Diabetic Foot Ulcers
ERIC Educational Resources Information Center
Ragab, Islam I.; Kamal, Ahmed
2017-01-01
Wound cleansing remains a corner stone in the management of diabetic foot ulcer. Hydrogen Peroxide (H[subscript 2]O[subscript 2]) and Povidone Iodine are topical antimicrobial agents but known to be toxic to cells involved in the wound healing cascade. The biggest challenge for the physicians and nurses is searching for a safe, noncytotoxic and…
Policy Meets Pathways: A State Policy Agenda for Transformational Change. DesignForScale Series
ERIC Educational Resources Information Center
Couturier, Lara K.
2014-01-01
A new national report released by Jobs for the Future (JFF) says that a decade of interventions and improvements have fallen short because states and campuses have not taken large enough steps to address their biggest challenge--helping the 12.8 million students enrolled in community colleges earn postsecondary degrees and credentials to find good…
USDA-ARS?s Scientific Manuscript database
One of the biggest challenges to successfully phytoremediate contaminated mineland soils is the identification of native plants that possess a broad adaptation to ecological sites and either exclude or uptake heavy metals of interest. This study evaluated forage concentrations of aluminum (Al), ars...
ERIC Educational Resources Information Center
Watkins, Paula G.; Razee, Husna; Richters, Juliet
2012-01-01
This article examines factors influencing English language education, participation and achievement among Karen refugee women in Australia. Data were drawn from ethnographic observations and interviews with 67 participants between 2009 and 2011, collected as part of a larger qualitative study exploring the well-being of Karen refugee women in…
Relevancy of the Massive Open Online Course (MOOC) about Sustainable Energy for Adolescents
ERIC Educational Resources Information Center
Aksela, Maija; Wu, Xiaomeng; Halonen, Julia
2016-01-01
Sustainable energy is one of the biggest global challenges today. This paper discusses how we can promote adolescents' learning of sustainable energy with the help of an international massive open online course (MOOC). The aim of this case study is to understand: (1) What do the adolescents find relevant in the MOOC course about sustainable…
ERIC Educational Resources Information Center
Isaacs, Eslyn B. H.; Friedrich, Christian
2011-01-01
It is estimated that 50-70% of all South African businesses are family-owned and that these businesses form the backbone of the South African economy, their qualities providing stability and resilience in the changing society of the nation. Succession is one of the biggest challenges for family business owners. Research shows that only 33% of all…
Differentiation of Teaching and Learning Mathematics: An Action Research Study in Tertiary Education
ERIC Educational Resources Information Center
Konstantinou-Katzi, Panagiota; Tsolaki, Eleni; Meletiou-Mavrotheris, Maria; Koutselini, Mary
2013-01-01
Diversity and differentiation within our classrooms, at all levels of education, is nowadays a fact. It has been one of the biggest challenges for educators to respond to the needs of all students in such a mixed-ability classroom. Teachers' inability to deal with students with different levels of readiness in a different way leads to school…
Osman, Houssam; Parikh, Janak; Patel, Shirali; Jeyarajah, D Rohan
2015-01-01
Background The present study was conducted to assess the preparedness of hepatopancreatobiliary (HPB) fellows upon entering fellowship, identify challenges encountered by HPB fellows during the initial part of their HPB training, and identify potential solutions to these challenges that can be applied during residency training. Methods A questionnaire was distributed to all HPB fellows in accredited HPB fellowship programmes in two consecutive academic years (n = 42). Reponses were then analysed. Results A total of 19 (45%) fellows responded. Prior to their fellowship, 10 (53%) were in surgical residency and the rest were in other surgical fellowships or surgical practice. Thirteen (68%) were graduates of university-based residency programmes. All fellows felt comfortable in performing basic laparoscopic procedures independently at the completion of residency and less comfortable in performing advanced laparoscopy. Eight (42%) fellows cited a combination of inadequate case volume and lack of autonomy during residency as the reasons for this lack of comfort. Thirteen (68%) identified inadequate preoperative workup and management as their biggest fear upon entering practice after general surgery training. A total of 17 (89%) fellows felt they were adequately prepared to enter HPB fellowship. Extra rotations in transplant, vascular or minimally invasive surgery were believed to be most helpful in preparing general surgery residents pursing HPB fellowships. Conclusions Overall, HPB fellows felt themselves to be adequately prepared for fellowship. Advanced laparoscopic procedures and the perioperative management of complex patients are two of the challenges facing HPB fellows. General surgery residents who plan to pursue an HPB fellowship may benefit from spending extra rotations on certain subspecialties. Focus on perioperative workup and management should be an integral part of residency and fellowship training. PMID:25387852
Osman, Houssam; Parikh, Janak; Patel, Shirali; Jeyarajah, D Rohan
2015-03-01
The present study was conducted to assess the preparedness of hepatopancreatobiliary (HPB) fellows upon entering fellowship, identify challenges encountered by HPB fellows during the initial part of their HPB training, and identify potential solutions to these challenges that can be applied during residency training. A questionnaire was distributed to all HPB fellows in accredited HPB fellowship programmes in two consecutive academic years (n = 42). Reponses were then analysed. A total of 19 (45%) fellows responded. Prior to their fellowship, 10 (53%) were in surgical residency and the rest were in other surgical fellowships or surgical practice. Thirteen (68%) were graduates of university-based residency programmes. All fellows felt comfortable in performing basic laparoscopic procedures independently at the completion of residency and less comfortable in performing advanced laparoscopy. Eight (42%) fellows cited a combination of inadequate case volume and lack of autonomy during residency as the reasons for this lack of comfort. Thirteen (68%) identified inadequate preoperative workup and management as their biggest fear upon entering practice after general surgery training. A total of 17 (89%) fellows felt they were adequately prepared to enter HPB fellowship. Extra rotations in transplant, vascular or minimally invasive surgery were believed to be most helpful in preparing general surgery residents pursing HPB fellowships. Overall, HPB fellows felt themselves to be adequately prepared for fellowship. Advanced laparoscopic procedures and the perioperative management of complex patients are two of the challenges facing HPB fellows. General surgery residents who plan to pursue an HPB fellowship may benefit from spending extra rotations on certain subspecialties. Focus on perioperative workup and management should be an integral part of residency and fellowship training. © 2014 International Hepato-Pancreato-Biliary Association.
2013-01-01
Background Antiretroviral therapy (ART) roll-out is fraught with challenges, many with serious repercussions. We explored and described patient behaviour-related challenges from the perspective of health care providers from non-governmental organisations involved in ART programmes in KwaZulu-Natal, South Africa. Methods A descriptive case study design using qualitative approach was applied during this study. Data was collected from nine key informants from the three biggest NGOs involved in ART roll-out using in-depth semi-structured interviews. Transcribing and coding for emergent themes was done by two independent reviewers. Ethical approval for the study was granted by the UNISA research ethics committee of The Faculty of Health Sciences. Written consent was obtained from directors of the three NGOs involved and individual audio taped informed consent was obtained from all study participants prior to data collection. Results Findings revealed six broad areas of patient behaviour challenges. These were patient behaviour related to socio-economic situation of patient (skipping of medication due to lack of food, or due to lack of transport fees), belief systems (traditional and religious), stigma (non- disclosure), sexual practices (non-acceptability of condoms, teenage pregnancies), escapism (drug and alcohol abuse) and opportunism (skipping medication in order to access disability grant, teenage pregnancies in order to access child grant). Conclusion New programmes need to address patient behaviour as a complex phenomenon requiring a multi-pronged approach that also addresses social norms and institutions. In the face of continued ART scale up, this is further evidence for the need for multi-sectoral collaboration to ensure successful and sustainable ART roll-out. PMID:23870285
48 CFR 1480.903 - Award in the face of challenge.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Award in the face of challenge. 1480.903 Section 1480.903 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Award in the face of challenge. (a) Award of a contract in the face of challenge may be made on the...
48 CFR 1480.903 - Award in the face of challenge.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Award in the face of challenge. 1480.903 Section 1480.903 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Award in the face of challenge. (a) Award of a contract in the face of challenge may be made on the...
Tsunami Hazard Assessment in Guam
NASA Astrophysics Data System (ADS)
Arcas, D.; Uslu, B.; Titov, V.; Chamberlin, C.
2008-12-01
The island of Guam is located approximately 1500 miles south of Japan, in the vicinity of the Mariana Trench. It is surrounded in close proximity by three subduction zones, Nankai-Taiwan, East Philippines and Mariana Trench that pose a considerable near to intermediate field tsunami threat. Tsunami catalogues list 14 tsunamigenic earthquake with Mw≥8.0 since 1900 only in this region, (Soloviev and Go, 1974; Lander, 1993; Iida, 1984; Lander and Lowell, 2002), however the island has not been significantly affected by some of the largest far-field events of the past century, such as the 1952 Kamchatka, 1960 Chile, and the 1964 Great Alaska earthquake. An assessment of the tsunami threat to the island from both near and far field sources, using forecast tools originally developed at NOAA's Pacific Marine Environmental Laboratory (PMEL) for real-time forecasting of tsunamis is presented here. Tide gauge records from 1952 Kamchatka, 1964 Alaska, and 1960 Chile earthquakes at Apra Harbor are used to validate our model set up, and to explain the limited impact of these historical events on Guam. Identification of worst-case scenarios, and determination of tsunamigenic effective source regions are presented for five vulnerable locations on the island via a tsunami sensitivity study. Apra Harbor is the site of a National Ocean Service (NOS) tide gauge and the biggest harbor on the island. Tumon Bay, Pago Bay, Agana Bay and Inarajan Bay are densely populated areas that require careful investigation. The sensitivity study shows that earthquakes from Eastern Philippines present a major threat to west coast facing sites, whereas the Marina Trench poses the biggest concern to the east coast facing sites.
Sustaining global progress in E and P health, safety, and environment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Arscott, R.L.; Edwardes, R.J.; Ognedal, M.
1996-12-01
The third International Conference on Health, Safety and Environment (HSE) was held in New Orleans in June 1996. During this meeting, the technical committee members were asked to complete a questionnaire with two questions: (1) What are the three biggest improvements in the industry`s performance in the HSE function over the past 5 years? and (2) What are the three biggest challenges for the next 5 years? The results from 30 replies from industry experts were compared with a similar survey conducted at the 1991 meeting, where the question was, What are the key action items the industry should takemore » to enhance performance over the next decade? This article gives the most frequently occurring comments cited by the 1996 technical committee relating to the 1991 recommendations. This may be considered a mid-decade review of worldwide E and P progress.« less
ERIC Educational Resources Information Center
Thaneerananon, Taveep; Triampo, Wannapong; Nokkaew, Artorn
2016-01-01
Nowadays, one of the biggest challenges of education in Thailand is the development and promotion of the students' thinking skills. The main purposes of this research were to develop an analytical thinking test for 6th grade students and evaluate the students' analytical thinking. The sample was composed of 3,567 6th grade students in 2014…
ERIC Educational Resources Information Center
Reddy, Anugula N.; Sinha, Shantha
2010-01-01
Persistently high dropout rates are one of the biggest challenges to fulfilling the right to education in India. This paper attempts to assess the magnitude of the problem of dropout. The paper critically reviews the evidence on some of the commonly cited reasons for dropout, including poverty, limited to access to credit, child labour, and…
Taking Stock: Interagency Integration in Stability Operations
2012-03-01
implementation of 3000.05. In May 2009, a report to Congress highlighted the biggest challenge to integration as the lack of civilian department and agency...ORHA) and later subsumed by the Coalition Provisional Authority (CPA). On May 11, 2004, NSPD 36, United States Government Operations in Iraq...military audience, although introductory presentations have been given at the U.S. Army Peacekeeping and Stability Operations Institute and Marine
Enhance your technology and enrich your bottom line.
Dunn, Cynthia
2008-01-01
Electronic systems can assist medical practice executives with their biggest practice management challenges, from finding uncollected revenue to tracking patients and supplies, and helping manage documentation and reports. This article explores a few technology opportunities that will boost your bottom line. You can start small and work up to the big purchases. Short-term successes in smoothing work flow or saving money will encourage bigger steps.
A Web of Learning: Beyond "Itsy Bitsy Spider," Preschool Students Learn Science Content Naturally
ERIC Educational Resources Information Center
Evitt, Marie Faust
2011-01-01
One of the author's biggest challenges as a preschool teacher is helping children in a group see and touch and do. Hands-on explorations are important for everyone, but essential for young children. How can young children do hands-on explorations of spiders and their webs? Teachers do not want children handling all sorts of spiders. They worry…
ERIC Educational Resources Information Center
Gilcreast, Jessica
2014-01-01
Six years ago Jessica Gilcreast accepted the position as the school librarian in a diverse urban elementary school (80 percent low-income student population). The library had a bare-bones automation system, block scheduling, and no library assistant. None of this, however, was her biggest challenge. Inheriting an institutional, cold,…
From Online Student to Online Instructor: Assistive Strategies
ERIC Educational Resources Information Center
McKnight, Jodi
2012-01-01
With the influx of online learning opportunities, online students and instructors are faced with a variety of challenges. Online students face the same challenges as do face-to-face learners, but by facing them in an online context, the interpretations of those challenges can lead to the success or failure of their overall educational experience.…
Multidrug-Resistant Gram-Negative Bacilli: Infection Control Implications.
Adler, Amos; Friedman, N Deborah; Marchaim, Dror
2016-12-01
Antimicrobial resistance is a common iatrogenic complication of both modern life and medical care. Certain multidrug resistant and extensively drug resistant Gram-negative organisms pose the biggest challenges to health care today, predominantly owing to a lack of therapeutic options. Containing the spread of these organisms is challenging, and in reality, the application of multiple control measures during an evolving outbreak makes it difficult to measure the relative impact of each measure. This article reviews the usefulness of various infection control measures in containing the spread of multidrug-resistant Gram-negative bacilli. Copyright © 2016 Elsevier Inc. All rights reserved.
Critical coastal issues of Sagar Island, east coast of India.
Gopinath, Girish
2010-01-01
Sagar Island, situated in the east coast of India and one of the biggest deltas in Sundarban group, faces coastal erosion and degradation of coastal vegetation and various natural hazards. Erosion is mainly due to clay mining, wave activities, and the impact of river and tidal currents of Muri Ganga and Hugly Rivers. Further, the coastal zone of Sagar Island faces increasingly severe problems of rapidly growing human population, deteriorating environmental quality, and loss of critical habitats. Sagar Island has been victimized several times by tropical cyclones and influenced daily by tidal fluctuations. The island needs immediate attention on the coastal zone in order to protect the shoreline and ecosystem. The capability of satellite remote sensing to provide synoptic, repetitive, and multispectral data has proved to be very useful in the inventory and monitoring of critical coastal issues. Sagar Island and its environs are subjected to both natural and anthropogenic activities that continuously modify the region.
ERIC Educational Resources Information Center
Spielberg, Lela
2011-01-01
There is widespread agreement that family engagement leads to increased student achievement, reduced drop-out rates, and a host of other positive outcomes for kids. Teachers are rarely trained or supported in engaging families, and, according to the 2005 MetLife Survey of the American Teacher, find family engagement to be their biggest challenge.…
ERIC Educational Resources Information Center
Ngoasheng, Asanda; Gachago, Daniela
2017-01-01
One of the biggest debates in South Africa is the use and usefulness of apartheid categories when analysing society and societal behaviour. This paper examines the process of learning and unlearning that took place when a political reporting lecturer and an academic staff developer sought to explain racially biased voting in South Africa and its…
How to recover from the financial market flu.
Doody, Dennis
2008-05-01
The widely publicized subprime mortgage crisis and soaring crude oil prices have contributed to considerable market volatility in recent months, inducing queasiness among institutional investors. A four-layer approach to asset allocation that carefully considers assets, liquidity, currency, and risk may be the best strategy for maintaining an institution's financial health through today's volatile market. Perhaps the biggest challenge in such financially turbulent times is keeping fear in check.
Nanophotonic biosensor for space exploration (PBSA instrument)
NASA Astrophysics Data System (ADS)
Pantoja, S.; Parro, V.; Nestler, J.; Geidel, S.; Martins, R.; Cuesta, F.; Elvira, J. G.; Sousa, A.
2017-11-01
One of the biggest challenges of Astrobiology is the search for clear signs of present or past life on other planetary bodies. Thus, this poster will describe the project "Photonic Biosensor for Space Application" (PBSA, www.pbsa-fp7.eu) founded by the Directorate-General for Enterprise and Industry (DG ENTR) within the European Commission and managed by the Unit S2 (Space Research) of the Research European Agency (REA).
Esophageal replacement in children: Challenges and long-term outcomes.
Soccorso, Giampiero; Parikh, Dakshesh H
2016-01-01
Replacement of a nonexistent or damaged esophagus continues to pose a significant challenge to pediatric surgeons. Various esophageal replacement grafts and techniques have not produced consistently good outcomes to emulate normal esophagus. Therefore, many techniques are still being practiced and recommended with no clear consensus. We present a concise literature review of the currently used techniques and with discussions on the advantages and anticipated morbidity. There are no randomized controlled pediatric studies to compare different types of esophageal replacements. Management and graft choice are based on geographical and personal predilections rather than on any discernible objective data. The biggest series with long-term outcome are reported for gastric transposition and colonic replacement. Comparison of different studies shows no significant difference in early (graft necrosis and anastomotic leaks) or late complications (strictures, poor feeding, gastro-esophageal reflux, tortuosity of the graft, and Barrett's esophagus). The biggest series seem to have lower complications than small series reflecting the decennials experience in their respective centers. Long-term follow-up is recommended following esophageal replacement for the development of late strictures, excessive tortuosity, and Barrett's changes within the graft. Once child overcomes initial morbidity and establishes oral feeding, long-term consequences and complications of pediatric esophageal replacement should be monitored and managed in adult life.
Esophageal replacement in children: Challenges and long-term outcomes
Soccorso, Giampiero; Parikh, Dakshesh H.
2016-01-01
Replacement of a nonexistent or damaged esophagus continues to pose a significant challenge to pediatric surgeons. Various esophageal replacement grafts and techniques have not produced consistently good outcomes to emulate normal esophagus. Therefore, many techniques are still being practiced and recommended with no clear consensus. We present a concise literature review of the currently used techniques and with discussions on the advantages and anticipated morbidity. There are no randomized controlled pediatric studies to compare different types of esophageal replacements. Management and graft choice are based on geographical and personal predilections rather than on any discernible objective data. The biggest series with long-term outcome are reported for gastric transposition and colonic replacement. Comparison of different studies shows no significant difference in early (graft necrosis and anastomotic leaks) or late complications (strictures, poor feeding, gastro-esophageal reflux, tortuosity of the graft, and Barrett's esophagus). The biggest series seem to have lower complications than small series reflecting the decennials experience in their respective centers. Long-term follow-up is recommended following esophageal replacement for the development of late strictures, excessive tortuosity, and Barrett's changes within the graft. Once child overcomes initial morbidity and establishes oral feeding, long-term consequences and complications of pediatric esophageal replacement should be monitored and managed in adult life. PMID:27365900
Celedon, Jose M; Cline, Kenneth
2013-02-01
Protein trafficking and localization in plastids involve a complex interplay between ancient (prokaryotic) and novel (eukaryotic) translocases and targeting machineries. During evolution, ancient systems acquired new functions and novel translocation machineries were developed to facilitate the correct localization of nuclear encoded proteins targeted to the chloroplast. Because of its post-translational nature, targeting and integration of membrane proteins posed the biggest challenge to the organelle to avoid aggregation in the aqueous compartments. Soluble proteins faced a different kind of problem since some had to be transported across three membranes to reach their destination. Early studies suggested that chloroplasts addressed these issues by adapting ancient-prokaryotic machineries and integrating them with novel-eukaryotic systems, a process called 'conservative sorting'. In the last decade, detailed biochemical, genetic, and structural studies have unraveled the mechanisms of protein targeting and localization in chloroplasts, suggesting a highly integrated scheme where ancient and novel systems collaborate at different stages of the process. In this review we focus on the differences and similarities between chloroplast ancestral translocases and their prokaryotic relatives to highlight known modifications that adapted them to the eukaryotic situation. This article is part of a Special Issue entitled: Protein Import and Quality Control in Mitochondria and Plastids. Copyright © 2012 Elsevier B.V. All rights reserved.
Kiechel, Walter
2012-11-01
In 1886, addressing the nascent American Society of Mechanical Engineers, Henry R. Towne proposed that "the management of works" be considered a modern art--thereby heralding the Management Century, when management as we know it came into being and shaped the world in which we work. Kiechel, a past editorial director of Harvard Business Publishing, elucidates the three eras that punctuate this period: the years leading up to World War II, during which scientific exactitude gave wings to a new managerial elite; the early postwar decades, managerialism's apogee of self-confidence and a time when wartime principles of strategy were adapted, sometimes ruthlessly, to the running of companies; and the 1980s to the present, years that saw fast-moving changes, disequilibrium, and a servitude to market forces but also ushered in globalism, unprecedented innovation, and heightened expectations about how workers are to be treated. Along the way he examines the contributions of thinkers such as Frederick Taylor, Elton Mayo, Peter Drucker, and Michael Porter. What lies ahead? Perhaps the biggest challenge facing the 21st-century company, Kiechel posits, is to truly free the spark of human imagination from the organization's tidal pull toward the status quo. There's almost always a better way, he concludes--and management will continue to seek it.
Ndejjo, Rawlance; Musoke, David; Musinguzi, Geofrey; Halage, Abdullah Ali; Carpenter, David O.; Ssempebwa, John C.
2016-01-01
Poor solid waste management is among the major challenges facing urban slums in developing countries including Uganda. Understanding community concerns and willingness towards involvement in solid waste management improvement initiatives is critical for informing interventions in slums. Methods. We used a cross-sectional study to collect quantitative data from 435 residents in two urban slums in central Uganda. A semistructured questionnaire was used which assessed waste collection practices, separation and disposal methods, concerns regarding solid wastes, and willingness to participate in waste separation and composting. Data was analysed using STATA 12. Results. Food remains (38%) and plastics (37%) formed the biggest proportion of wastes generated in households. Most households (35.9%) disposed of general wastes by open dumping while 27% disposed of plastics by burning. Only 8.8% of households conducted composting while 55% carried out separation for some decomposable wastes. Separation was carried out for only banana peelings and leftover foods for feeding animals. Respondents expressed high willingness to separate (76.6%) and compost (54.9%) solid wastes. Conclusion. Practices in waste disposal and separation were poor despite high willingness to participate in initiatives to improve waste management, highlighting a need for authorities to engage residents of slums to improve their practices. PMID:27066081
Mukama, Trasias; Ndejjo, Rawlance; Musoke, David; Musinguzi, Geofrey; Halage, Abdullah Ali; Carpenter, David O; Ssempebwa, John C
2016-01-01
Poor solid waste management is among the major challenges facing urban slums in developing countries including Uganda. Understanding community concerns and willingness towards involvement in solid waste management improvement initiatives is critical for informing interventions in slums. We used a cross-sectional study to collect quantitative data from 435 residents in two urban slums in central Uganda. A semistructured questionnaire was used which assessed waste collection practices, separation and disposal methods, concerns regarding solid wastes, and willingness to participate in waste separation and composting. Data was analysed using STATA 12. Food remains (38%) and plastics (37%) formed the biggest proportion of wastes generated in households. Most households (35.9%) disposed of general wastes by open dumping while 27% disposed of plastics by burning. Only 8.8% of households conducted composting while 55% carried out separation for some decomposable wastes. Separation was carried out for only banana peelings and leftover foods for feeding animals. Respondents expressed high willingness to separate (76.6%) and compost (54.9%) solid wastes. Practices in waste disposal and separation were poor despite high willingness to participate in initiatives to improve waste management, highlighting a need for authorities to engage residents of slums to improve their practices.
Constructing Concept Schemes From Astronomical Telegrams Via Natural Language Clustering
NASA Astrophysics Data System (ADS)
Graham, Matthew; Zhang, M.; Djorgovski, S. G.; Donalek, C.; Drake, A. J.; Mahabal, A.
2012-01-01
The rapidly emerging field of time domain astronomy is one of the most exciting and vibrant new research frontiers, ranging in scientific scope from studies of the Solar System to extreme relativistic astrophysics and cosmology. It is being enabled by a new generation of large synoptic digital sky surveys - LSST, PanStarrs, CRTS - that cover large areas of sky repeatedly, looking for transient objects and phenomena. One of the biggest challenges facing these is the automated classification of transient events, a process that needs machine-processible astronomical knowledge. Semantic technologies enable the formal representation of concepts and relations within a particular domain. ATELs (http://www.astronomerstelegram.org) are a commonly-used means for reporting and commenting upon new astronomical observations of transient sources (supernovae, stellar outbursts, blazar flares, etc). However, they are loose and unstructured and employ scientific natural language for description: this makes automated processing of them - a necessity within the next decade with petascale data rates - a challenge. Nevertheless they represent a potentially rich corpus of information that could lead to new and valuable insights into transient phenomena. This project lies in the cutting-edge field of astrosemantics, a branch of astroinformatics, which applies semantic technologies to astronomy. The ATELs have been used to develop an appropriate concept scheme - a representation of the information they contain - for transient astronomy using hierarchical clustering of processed natural language. This allows us to automatically organize ATELs based on the vocabulary used. We conclude that we can use simple algorithms to process and extract meaning from astronomical textual data.
Web Accessibility for Older Adults: A Comparative Analysis of Disability Laws.
Yang, Y Tony; Chen, Brian
2015-10-01
Access to the Internet is increasingly critical for health information retrieval, access to certain government benefits and services, connectivity to friends and family members, and an array of commercial and social services that directly affect health. Yet older adults, particularly those with disabilities, are at risk of being left behind in this growing age- and disability-based digital divide. The Americans with Disabilities Act (ADA) was designed to guarantee older adults and persons with disabilities equal access to employment, retail, and other places of public accommodation. Yet older Internet users sometimes face challenges when they try to access the Internet because of disabilities associated with age. Current legal interpretations of the ADA, however, do not consider the Internet to be an entity covered by law. In this article, we examine the current state of Internet accessibility protection in the United States through the lens of the ADA, sections 504 and 508 of the Rehabilitation Act, state laws and industry guidelines. We then compare U.S. rules to those of OECD (Organisation for Economic Co-Operation and Development) countries, notably in the European Union, Canada, Japan, Australia, and the Nordic countries. Our policy recommendations follow from our analyses of these laws and guidelines, and we conclude that the biggest challenge in bridging the age- and disability-based digital divide is the need to extend accessibility requirements to private, not just governmental, entities and organizations. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Weaver, Nancy L; Brixey, Suzanne N; Williams, Janice; Nansel, Tonja R
2013-03-01
Injuries involving motor vehicles continue to be the biggest threat to the safety of children. Although child safety seats (CSS) have been established as a central countermeasure in decreasing injury risk, the majority of parents do not use the correct car seat correctly. There are many challenges in promoting correct car seat use, which itself is a complex behavior. To advance this critical protective behavior, the public health community would benefit from clarifying CSS messaging, communicating clearly, and addressing the conflicting recommendations of product use. In this article, we present current challenges in promoting CSS use and draw on health communication and other fields to offer recommendations for future work in this area.
NASA Technical Reports Server (NTRS)
Bazley, Jesse A.
2011-01-01
This presentation will discuss the International Space Station s (ISS) Regenerative Environmental Control and Life Support System (ECLSS) operations with discussion of the on-orbit lessons learned, specifically regarding the challenges that have been faced as the system has expanded with a growing ISS crew. Over the 10 year history of the ISS, there have been numerous challenges, failures, and triumphs in the quest to keep the crew alive and comfortable. Successful operation of the ECLSS not only requires maintenance of the hardware, but also management of the station resources in case of hardware failure or missed re-supply. This involves effective communication between the primary International Partners (NASA and Roskosmos) and the secondary partners (JAXA and ESA) in order to keep a reserve of the contingency consumables and allow for re-supply of failed hardware. The ISS ECLSS utilizes consumables storage for contingency usage as well as longer-term regenerative systems, which allow for conservation of the expensive resources brought up by re-supply vehicles. This long-term hardware, and the interactions with software, was a challenge for Systems Engineers when they were designed and require multiple operational workarounds in order to function continuously. On a day-to-day basis, the ECLSS provides big challenges to the on console controllers. Main challenges involve the utilization of the resources that have been brought up by the visiting vehicles prior to undocking, balance of contributions between the International Partners for both systems and resources, and maintaining balance between the many interdependent systems, which includes providing the resources they need when they need it. The current biggest challenge for ECLSS is the Regenerative ECLSS system, which continuously recycles urine and condensate water into drinking water and oxygen. These systems were brought to full functionality on STS-126 (ULF-2) mission. Through system failures and recovery, the ECLSS console has learned how to balance the water within the systems, store and use water for contingencies, and continue to work with the International Partners for short-term failures. Through these challenges and the system failures, the most important lesson learned has been the importance of redundancy and operational workarounds. It is only because of the flexibility of the hardware and the software that flight controllers have the opportunity to continue operating the system as a whole for mission success.
ERIC Educational Resources Information Center
Mmbwanga, Daniel M.; Matemba, Collins K.; Bota, Kennedy N.
2015-01-01
The mentally challenged child (MC) can achieve a lot if the right environment and curriculum are designed for him/her. However, the realization of the desirable outcomes faces many challenges. The objective of the study was to examine institutional and personnel-related challenges facing education programs for the MC persons at Kaimosi Special…
Understanding Leadership in Schools Facing Challenging Circumstances: A Chilean Case Study
ERIC Educational Resources Information Center
Ahumada, Luis; Galdames, Sergio; Clarke, Simon
2016-01-01
During the last 10 years, research into schools facing challenging circumstances has attracted the attention of researchers around the world. The aim of this study was to understand the challenges that school leaders face as they per form their work, the nature of the context in which these challenges arise, the strategies school leaders adopt to…
A Tutorial on Adaptive Design Optimization
Myung, Jay I.; Cavagnaro, Daniel R.; Pitt, Mark A.
2013-01-01
Experimentation is ubiquitous in the field of psychology and fundamental to the advancement of its science, and one of the biggest challenges for researchers is designing experiments that can conclusively discriminate the theoretical hypotheses or models under investigation. The recognition of this challenge has led to the development of sophisticated statistical methods that aid in the design of experiments and that are within the reach of everyday experimental scientists. This tutorial paper introduces the reader to an implementable experimentation methodology, dubbed Adaptive Design Optimization, that can help scientists to conduct “smart” experiments that are maximally informative and highly efficient, which in turn should accelerate scientific discovery in psychology and beyond. PMID:23997275
ERIC Educational Resources Information Center
Hora, Matthew T.; Bouwma-Gearhart, Jana; Park, Hyoung Joon
2014-01-01
A defining characteristic of current U.S. educational policy is the use of data to inform decisions about resource allocation, teacher hiring, and curriculum and instruction. Perhaps the biggest challenge to data-driven decision making (DDDM) is that data use alone does not automatically result in improved teaching and learning. Research indicates…
Comparative Activity-Based Flavin-Dependent Oxidase Profiling.
Krysiak, Joanna; Breinbauer, Rolf
2017-01-01
Activity-based protein profiling (ABPP) has become a powerful chemoproteomic technology allowing for the dissection of complex ligand-protein interactions in their native cellular environment. One of the biggest challenges for ABPP is the extension of the proteome coverage. In this chapter a new ABPP strategy dedicated to monoamine oxidases (MAO) is presented. These enzymes are representative examples of flavin-dependent oxidases, playing a crucial role in the regulation of nervous system signaling.
Best Practices Case Study: Pulte Homes and Communities of Del Webb, Las Vegas Division
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
2009-10-01
Case study of Pulte Homes Las Vegas Division, who certified nearly 1,200 homes to the DOE Builders Challenge between 2008 and 2012. All of the homes by Las Vegas’ biggest builder achieved HERS scores of lower than 70, and many floor plans got down to the mid 50s, with ducts located in sealed attics insulated along the roof line, advanced framing, and extra attention to air sealing.
Challenges Facing a Deaf Family Member Concerning a Loved One’s Dying
Kehl, Karen A.; Gartner, Constance M.
2010-01-01
Individuals who are Deaf face challenges both similar and unique from those faced by hearing individuals when a family member is dying. This study was guided by the question “What are the challenges faced by a Deaf family member when a loved one is dying?” Methods - This qualitative study is guided by critical theory and an interpretive perspective. Robert, a college-educated older adult who has been Deaf from birth was interviewed in American Sign Language using a death history format. Results – There are challenges for Deaf family members that affect communication with both the dying person and health care professionals. Patient-family communication issues included physical challenges and financial challenges. Lack of cultural competence concerning the Deaf community created challenges communicating with professionals. Decision-making was also a challenge. Conclusions These findings provide a framework for future research concerning the needs of Deaf individuals facing the end of life and provide guidance for clinicians. PMID:19910395
Measuring e-Commerce service quality from online customer review using sentiment analysis
NASA Astrophysics Data System (ADS)
Kencana Sari, Puspita; Alamsyah, Andry; Wibowo, Sulistyo
2018-03-01
The biggest e-Commerce challenge to understand their market is to chart their level of service quality according to customer perception. The opportunities to collect user perception through online user review is considered faster methodology than conducting direct sampling methodology. To understand the service quality level, sentiment analysis methodology is used to classify the reviews into positive and negative sentiment for five dimensions of electronic service quality (e-Servqual). As case study in this research, we use Tokopedia, one of the biggest e-Commerce service in Indonesia. We obtain the online review comments about Tokopedia service quality during several month observations. The Naïve Bayes classification methodology is applied for the reason of its high-level accuracy and support large data processing. The result revealed that personalization and reliability dimension required more attention because have high negative sentiment. Meanwhile, trust and web design dimension have high positive sentiments that means it has very good services. The responsiveness dimension have balance sentiment positive and negative.
Homeland Security. Management Challenges Facing Federal Leadership
2002-12-01
Security Management Challenges Facing Federal Leadership 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...including attention to management practices and key success factors. HOMELAND SECURITY Management Challenges Facing Federal Leadership www.gao.gov/cgi...significant management and coordination challenges if it is to provide this leadership and be successful in preventing and responding to any future
ERIC Educational Resources Information Center
Black, Ronald
2017-01-01
Faculty who mentor online doctoral candidates face many of the same challenges and opportunities as those mentoring doctoral candidates in traditional, face-to-face modalities. The main difference is that E-Mentoring is based on interacting in the online space rather than interacting face-to-face, which may present challenges for both the…
2011-06-01
there a free-market economist in the House?, American Journal of Economics and Sociology, 66(2): 309-334. Jasny, B. R., Zahn, L.M., & Marshall, E...1 The Mathematics of Aggregation, Interdependence, Organizations and Systems of Nash equilibria (NE): A replacement for Game Theory...level data to group, organization and systems levels, making it one of social science’s biggest challenges, if not the most important (Giles, 2011). For
ERIC Educational Resources Information Center
Lockwood, Jeff
2008-01-01
NASA (National Aeronautics and Space Administration) is one of the biggest employers of engineers in the world--about 90,000 among its own employees and its corporate partners. So it's not surprising that NASA wants kids to learn more about engineering, become interested in the things engineers do, and experience the world of engineering…
ERIC Educational Resources Information Center
DuBose, Cheryl O.
2017-01-01
International students face many challenges when pursuing a degree in higher education. Communication and cultural differences are typically cited as the most challenging aspects of any study abroad program. Students attempting to complete a healthcare program face sometimes insurmountable issues, as communication, cultural differences, and…
The Sisters of Mercy in the Crimean War: Lessons for Catholic health care
Paradis, Mary Raphael; Hart, Edith Mary; O’Brien, Mary Judith
2017-01-01
In 1856, an appeal went out to nurses in both England and Ireland, and especially to religious nurses, to care for the troops fighting in the Crimean War. The Sisters of Mercy, founded in 1831 by Venerable Catherine McAuley, answered that call. This article describes the enormous challenges the Sisters faced in that mission, which was a test of their nursing skills, flexibility, organizational ability, and their spirit of mercy. The challenges they faced professionally and as religious Sisters, the manner in which they faced those challenges, and their spiritual lives as religious women shaped their ability to give comprehensive care. Some applications are made to the challenges which religious communities and organizations working in health care face in our country at this time. Summary: This article describes the challenges faced by a group of Sisters of Mercy from England and Ireland who volunteered to serve as nurses in the Crimean War from 1856 to 1858. Applications are made to challenges which are faced by religious communities and organizations in the current secular healthcare environment. PMID:28392597
The Sisters of Mercy in the Crimean War: Lessons for Catholic health care.
Paradis, Mary Raphael; Hart, Edith Mary; O'Brien, Mary Judith
2017-02-01
In 1856, an appeal went out to nurses in both England and Ireland, and especially to religious nurses, to care for the troops fighting in the Crimean War. The Sisters of Mercy, founded in 1831 by Venerable Catherine McAuley, answered that call. This article describes the enormous challenges the Sisters faced in that mission, which was a test of their nursing skills, flexibility, organizational ability, and their spirit of mercy. The challenges they faced professionally and as religious Sisters, the manner in which they faced those challenges, and their spiritual lives as religious women shaped their ability to give comprehensive care. Some applications are made to the challenges which religious communities and organizations working in health care face in our country at this time. Summary: This article describes the challenges faced by a group of Sisters of Mercy from England and Ireland who volunteered to serve as nurses in the Crimean War from 1856 to 1858. Applications are made to challenges which are faced by religious communities and organizations in the current secular healthcare environment.
Community in Online Higher Education: Challenges and Opportunities
ERIC Educational Resources Information Center
Arasaratnam-Smith, Lily A.; Northcote, Maria
2017-01-01
Exploring the challenges and opportunities associated with the concepts of community and communication in online higher education, this paper reconsiders the intention to replicate face-to-face learning and teaching strategies in online learning environments. Rather than beginning with the assumption that face-to-face education is the prototype…
Adaptive management for a turbulent future
Allen, Craig R.; Fontaine, J.J.; Pope, K.L.; Garmestani, A.S.
2011-01-01
The challenges that face humanity today differ from the past because as the scale of human influence has increased, our biggest challenges have become global in nature, and formerly local problems that could be addressed by shifting populations or switching resources, now aggregate (i.e., "scale up") limiting potential management options. Adaptive management is an approach to natural resource management that emphasizes learning through management based on the philosophy that knowledge is incomplete and much of what we think we know is actually wrong. Adaptive management has explicit structure, including careful elucidation of goals, identification of alternative management objectives and hypotheses of causation, and procedures for the collection of data followed by evaluation and reiteration. It is evident that adaptive management has matured, but it has also reached a crossroads. Practitioners and scientists have developed adaptive management and structured decision making techniques, and mathematicians have developed methods to reduce the uncertainties encountered in resource management, yet there continues to be misapplication of the method and misunderstanding of its purpose. Ironically, the confusion over the term "adaptive management" may stem from the flexibility inherent in the approach, which has resulted in multiple interpretations of "adaptive management" that fall along a continuum of complexity and a priori design. Adaptive management is not a panacea for the navigation of 'wicked problems' as it does not produce easy answers, and is only appropriate in a subset of natural resource management problems where both uncertainty and controllability are high. Nonetheless, the conceptual underpinnings of adaptive management are simple; there will always be inherent uncertainty and unpredictability in the dynamics and behavior of complex social-ecological systems, but management decisions must still be made, and whenever possible, we should incorporate learning into management. ?? 2010 .
Adaptive Management for a Turbulent Future
Allen, Craig R.; Fontaine, Joseph J.; Pope, Kevin L.; Garmestani, Ahjond S.
2011-01-01
The challenges that face humanity today differ from the past because as the scale of human influence has increased, our biggest challenges have become global in nature, and formerly local problems that could be addressed by shifting populations or switching resources, now aggregate (i.e., "scale up") limiting potential management options. Adaptive management is an approach to natural resource management that emphasizes learning through management based on the philosophy that knowledge is incomplete and much of what we think we know is actually wrong. Adaptive management has explicit structure, including careful elucidation of goals, identification of alternative management objectives and hypotheses of causation, and procedures for the collection of data followed by evaluation and reiteration. It is evident that adaptive management has matured, but it has also reached a crossroads. Practitioners and scientists have developed adaptive management and structured decision making techniques, and mathematicians have developed methods to reduce the uncertainties encountered in resource management, yet there continues to be misapplication of the method and misunderstanding of its purpose. Ironically, the confusion over the term "adaptive management" may stem from the flexibility inherent in the approach, which has resulted in multiple interpretations of "adaptive management" that fall along a continuum of complexity and a priori design. Adaptive management is not a panacea for the navigation of 'wicked problems' as it does not produce easy answers, and is only appropriate in a subset of natural resource management problems where both uncertainty and controllability are high. Nonetheless, the conceptual underpinnings of adaptive management are simple; there will always be inherent uncertainty and unpredictability in the dynamics and behavior of complex social-ecological systems, but management decisions must still be made, and whenever possible, we should incorporate learning into management. Published by Elsevier Ltd.
Maluka, Stephen; Kamuzora, Peter; San Sebastiån, Miguel; Byskov, Jens; Olsen, Øystein E; Shayo, Elizabeth; Ndawi, Benedict; Hurtig, Anna-Karin
2010-08-01
Priority-setting has become one of the biggest challenges faced by health decision-makers worldwide. Fairness is a key goal of priority-setting and Accountability for Reasonableness has emerged as a guiding framework for fair priority-setting. This paper describes the processes of setting health care priorities in Mbarali district, Tanzania, and evaluates the descriptions against Accountability for Reasonableness. Key informant interviews were conducted with district health managers, local government officials and other stakeholders using a semi-structured interview guide. Relevant documents were also gathered and group priority-setting in the district was observed. The results indicate that, while Tanzania has a decentralized public health care system, the reality of the district level priority-setting process was that it was not nearly as participatory as the official guidelines suggest it should have been. Priority-setting usually occurred in the context of budget cycles and the process was driven by historical allocation. Stakeholders' involvement in the process was minimal. Decisions (but not the reasoning behind them) were publicized through circulars and notice boards, but there were no formal mechanisms in place to ensure that this information reached the public. There were neither formal mechanisms for challenging decisions nor an adequate enforcement mechanism to ensure that decisions were made in a fair and equitable manner. Therefore, priority-setting in Mbarali district did not satisfy all four conditions of Accountability for Reasonableness; namely relevance, publicity, appeals and revision, and enforcement. This paper aims to make two important contributions to this problematic situation. First, it provides empirical analysis of priority-setting at the district level in the contexts of low-income countries. Second, it provides guidance to decision-makers on how to improve fairness, legitimacy, and sustainability of the priority-setting process. (c) 2010 Elsevier Ltd. All rights reserved.
DAsHER CD: Developing a Data-Oriented Human-Centric Enterprise Architecture for EarthCube
NASA Astrophysics Data System (ADS)
Yang, C. P.; Yu, M.; Sun, M.; Qin, H.; Robinson, E.
2015-12-01
One of the biggest challenges that face Earth scientists is the resource discovery, access, and sharing in a desired fashion. EarthCube is targeted to enable geoscientists to address the challenges by fostering community-governed efforts that develop a common cyberinfrastructure for the purpose of collecting, accessing, analyzing, sharing and visualizing all forms of data and related resources, through the use of advanced technological and computational capabilities. Here we design an Enterprise Architecture (EA) for EarthCube to facilitate the knowledge management, communication and human collaboration in pursuit of the unprecedented data sharing across the geosciences. The design results will provide EarthCube a reference framework for developing geoscience cyberinfrastructure collaborated by different stakeholders, and identifying topics which should invoke high interest in the community. The development of this EarthCube EA framework leverages popular frameworks, such as Zachman, Gartner, DoDAF, and FEAF. The science driver of this design is the needs from EarthCube community, including the analyzed user requirements from EarthCube End User Workshop reports and EarthCube working group roadmaps, and feedbacks or comments from scientists obtained by organizing workshops. The final product of this Enterprise Architecture is a four-volume reference document: 1) Volume one is this document and comprises an executive summary of the EarthCube architecture, serving as an overview in the initial phases of architecture development; 2) Volume two is the major body of the design product. It outlines all the architectural design components or viewpoints; 3) Volume three provides taxonomy of the EarthCube enterprise augmented with semantics relations; 4) Volume four describes an example of utilizing this architecture for a geoscience project.
Fan, Mingsheng; Shen, Jianbo; Yuan, Lixing; Jiang, Rongfeng; Chen, Xinping; Davies, William J; Zhang, Fusuo
2012-01-01
In recent years, agricultural growth in China has accelerated remarkably, but most of this growth has been driven by increased yield per unit area rather than by expansion of the cultivated area. Looking towards 2030, to meet the demand for grain and to feed a growing population on the available arable land, it is suggested that annual crop production should be increased to around 580 Mt and that yield should increase by at least 2% annually. Crop production will become more difficult with climate change, resource scarcity (e.g. land, water, energy, and nutrients) and environmental degradation (e.g. declining soil quality, increased greenhouse gas emissions, and surface water eutrophication). To pursue the fastest and most practical route to improved yield, the near-term strategy is application and extension of existing agricultural technologies. This would lead to substantial improvement in crop and soil management practices, which are currently suboptimal. Two pivotal components are required if we are to follow new trajectories. First, the disciplines of soil management and agronomy need to be given increased emphasis in research and teaching, as part of a grand food security challenge. Second, continued genetic improvement in crop varieties will be vital. However, our view is that the biggest gains from improved technology will come most immediately from combinations of improved crops and improved agronomical practices. The objectives of this paper are to summarize the historical trend of crop production in China and to examine the main constraints to the further increase of crop productivity. The paper provides a perspective on the challenge faced by science and technology in agriculture which must be met both in terms of increased crop productivity but also in increased resource use efficiency and the protection of environmental quality.
The European flood risk directive: challenges for research
NASA Astrophysics Data System (ADS)
Mostert, E.; Junier, S. J.
2009-07-01
In recent years, flood management has shifted from protection against floods to managing the risks of floods. In Europe, this shift is reflected in the Flood risk directive of October 2007 (2007/60/EC; FRD). The FRD requires EU Member States to undertake a preliminary assessment of flood risks and, for areas with a significant flood risk, to prepare flood hazard and flood risk maps and flood risk management plans. The purpose of this paper is to introduce the FRD and discuss the challenges that the FRD poses to research. These challenges include the issue how to define and measure ''flood risk'', the selection of alternatives to be assessed, coping with uncertainty, risk communication, nurturing trust and promoting collaboration. These research challenges cannot be addressed properly within any single discipline and without involving the flood risk managers and other stakeholders. The paper therefore concludes that there is a large need for interdisciplinary and participatory research. This constitutes in fact the biggest research challenge.
Chances and challenges of forest scale CO2 enrichment
NASA Astrophysics Data System (ADS)
Körner, Christian
2016-04-01
Rising CO2 is changing the biosphere's diet. As with any dietary change, both amount and quality of food matter. Atmospheric CO2 enrichment is clearly providing a rather one-sided, C-rich diet. Hence, the reaiistic experimental simulation of its effect on the single biggest C reservoir of the biosphere, that is forest, requires experimental conditions that resemble exactly that situation. In the past, trees where most commonly exposed to elevated CO2 while provided with ample other constituents of a plant's diet (soil nutrients), yielding exaggerated growth stimulation, unlikely to reflect real world responses. So, by either selecting fertile soils, disturbing the system by fire or planting activities, offering ample soil space to isolated individuals or even adding fertilizer, almost any CO2-response can be 'designed'. The 'art' of designing future Free Air CO2 Enrichment (FACE) experiments will be to avoid exactly these pitfalls. Plants can incorporate additional C only to the extent the provision of chemical elements other than C will permit, given the stoichiometry of life. Site selection (soil fertility), degree of canopy closure, recent disturbance regime or successional stage will influence CO2 effects. It is the fundamental dilemma in CO2-enrichment research that simple, homogenous, artificial test systems offer statistical power, while systems that account for 'naturalness' and species diversity do not. Any new FACE program needs to handle that tradeoff between precision and relevance. In this presentation I will advocate a pragmatic approach that will inevitably have to lean on individual tree responses, across a wide as possible range of neighborhoods, age and growth conditions, with the statistical power depending in obtaining the best possible pre-treatment traits and responses. By illustrating the results of 15 years of FACE with 30-40 m tall forest trees, I will caution against over-optimistic ecosystem scale approaches with just ONE technology, given the sheer size such test systems would require. I rather suggest combining the best choice technology at different scales, which is not necessarily the most costly FACE approach. FACE emerged from overestimating potential bias from atmospheric conditions and greatly unerestimating the key role of soil conditions and biodiversity. Reference: Körner C (2006) Plant CO2 responses: an issue of definition, time and resource supply. New Phytol 172:393-411. Bader MKF, et al. (2013) Central European hardwood trees in a high-CO2 future: synthesis of an 8-year forest canopy CO2 enrichment project. J Ecol 101:1509-1519.
Chemistry and Biochemistry of Dietary Polyphenols
Tsao, Rong
2010-01-01
Polyphenols are the biggest group of phytochemicals, and many of them have been found in plant-based foods. Polyphenol-rich diets have been linked to many health benefits. This paper is intended to review the chemistry and biochemistry of polyphenols as related to classification, extraction, separation and analytical methods, their occurrence and biosynthesis in plants, and the biological activities and implications in human health. The discussions are focused on important and most recent advances in the above aspects, and challenges are identified for future research. PMID:22254006
Positively essential: traditional birth attendants in Malawi.
Stronge, Shirley
2011-06-01
One of the biggest challenges for healthcare professionals working in developing countries is the lack of trained personnel to carry out much needed health care provision. Shirley Stronge worked as a nurse/midwife tutor in a rural area in the north of Malawi. Millennium Development Goals four and five have focused our attention on the care required by mothers and newborns. Shirley has chosen to reflect on the role of Traditional Birth Attendants in the north of Malawi and their positive impact on maternity services in this area.
Stabilized wide bandgap MAPbBr xI 3-x perovskite by enhanced grain size and improved crystallinity
Hu, Miao; Bi, Cheng; Yuan, Yongbo; ...
2015-12-07
In this study, the light instability of CH 3NH 3PbI xBr 3–x has been raised one of the biggest challenges for its application in tandem solar cells. Here we show that an improved crystallinity and grain size of CH 3NH 3PbI xBr 3–x films could stabilize these materials under one sun illumination, improving both the efficiency and stability of the wide-bandgap perovskite solar cells.
Malakar, Arindam; Islam, Samirul; Ali, Md Ashif; Ray, Sugata
2016-10-01
Increasing arsenic contamination in the groundwater is one of the biggest environmental challenges that the Bengal delta is facing today. Groundwater is still the main source of water for a large number of population in this region and therefore, significant presence of toxic arsenic has a direct consequence on human lives here. Moreover, arsenic also enters into the food chain through the consumed agricultural products grown in this area. Therefore, acquiring knowledge about the ever-changing map of arsenic contamination and employing adequate protective measures are of utmost importance. Here, we present a comprehensive municipal ward-wise map of the arsenic content of the shallow groundwater table of Kolkata-the most important and highly population dense city of the delta. Comparison with previously available data reveals a rapid change and the grim situation for the city. Our study suggests that it should be an immediate task of the administration to extend treated water service to the whole population of the city for direct consumption, and artificial recharge and maximum rainwater replenishment need to be taken up with utmost urgency to avoid intrusion of toxicity in biological food chains via agricultural products. We hope our study would drive the city planners to reconsider the existing urbanization and development plans of all the cities, placed over arsenic-contaminated groundwater aquifers.
Improving the engineering properties of PLA for 3D printing and beyond
NASA Astrophysics Data System (ADS)
Rocha Gutierrez, Carmen Raquel
Additive manufacturing (AM), now more commonly known as 3D printing, has been classified as efficient, fast, and practical in the prototyping sector of product development. In the work presented here, we will use one of the AM techniques known as Material extrusion 3D printing (ME3DP), which has all the advantages of AM. However, one of the biggest challenges facing ME3DP technologies is the limitation of the range of materials used by this technique. Acrylonitrile butadiene styrene (ABS) and poly-lactic acid (PLA) are currently the most common thermoplastics materials used in ME3DP because of their ability to melt and be reprocessed. PLA is a biodegradable polymer derived from renewable sources such as corn, and sugarcane. The expanded use of this polymer over traditional petroleum-based plastics (ABS) will decrease the demand on petrochemicals, and also lead to less non-biodegradable polymeric waste. While PLA offers an eco-friendly solution for polymeric 3D printing, the mechanical performance is limited by PLA's inherent characteristics (such as moisture absorbance) that may degrade the plastic during processing. PLA novel systems were used through this research maintaining the compatibility with material extrusion 3D printers. The purpose of this investigation is to alter the physical properties of PLA with sustainable additives in order to improve the end use products from this material.
Calorie-labelling in catering outlets: acceptability and impacts on food sales.
Nikolaou, Charoula K; Lean, Michael E J; Hankey, Catherine R
2014-10-01
Obesity is the biggest challenge facing preventive medicine. Calorie-labelling has been suggested as a way of changing the architecture of an 'obesogenic' environment without limiting consumer choice. This study examined the effect of calorie-labelling on sales of food items at catering outlets on a city-centre university campus. Sales data were collected for two consecutive months in 2013 on three UK university sites (two with calorie-labelling during second month, one control) and analysed with chi-square 'Goodness-of-Fit' tests. A questionnaire seeking consumers' views and use of the calorie-labelling was administered and analysed at group-level with chi-square tests. In intervention vs control sites, total sales of all labelled items fell significantly (-17% vs -2%, p<0.001) for the month with calorie-labelling. Calorie-labelling was associated with substantially reduced sales of high-calorie labelled items, without any compensatory changes in unlabelled alternative items. Among 1166 student- and 646 staff-respondents, 56% reported using the calorie-labels, 97% of them to make lower-calorie choices. More females (63%) than males (40%) reported being influenced by calorie-labels when choosing foods (p=0.01). This study provides evidence, beyond that from single-meal exposures, for the acceptability of meal calorie-labelling and its potential as an effective low-cost anti-obesity measure. Copyright © 2014 Elsevier Inc. All rights reserved.
Challenges of Virtual School Leadership
ERIC Educational Resources Information Center
Richardson, Jayson W.; LaFrance, Jason; Beck, Dennis
2015-01-01
The purpose of this case study was to examine challenges faced by virtual school leaders in the United States. Through semistructured interviews, the researchers explored challenges faced by eighteen leaders of fully online or blended online programs. Analysis revealed six main challenges: funding, staff, accountability, time, parents, and…
Serving women who use drugs in Delhi, India: challenges and achievements.
Sarin, Enisha; Selhore, Elizabeth
2008-04-01
Sharan and Sahara, two NGOs working in Delhi, India, in the field of drug use and HIV/AIDS, present some key challenges as well as lessons learned in working with women who use drugs. Although there is no official estimate of the number of women drug users in Delhi, outreach reports indicate a hidden population of women users in the slums and streets of Delhi. A rapid situation assessment (RSA) conducted in 2000 by Sharan found urban poor women using drugs in Delhi with multiple issues related to their health, livelihoods, and relationships that put them at risk of severe health problems including HIV. The findings of the RSA led to intensified and focused intervention for women users by Sahara and Sharan. This is a discussion on a gender specific intervention ongoing in Delhi by delineating the particular achievements and challenges faced in working with women who use drugs. The article also looks at broader challenges that are outside the scope of this particular intervention but which nevertheless affect the well being of women who use drugs. Out of the 3700 women who have been rehabilitated in Sahara, 40% have found employment, while another 10% have been reintegrated into their families. There is however, an overdependence on its services that impedes their successful transition to mainstream life. One of the biggest limitations in the design of drug treatment interventions in Delhi is that there is a lack of diverse treatment options for women users. Only indoor detoxification and rehabilitation facilities are available for women; even these not offering a quality of care commensurate with the needs of the women. Lack of mental health care in drug treatment centres is felt to be a huge gap in services. Finally, NGOs like Sharan and Sahara are obliged to take up the entire continuum of care services which limits their ability to provide optimal care and services to women who use drugs. Lack of funds and lack of understanding among funding agencies about issues of women users are additional limitations in service provision. A multi-sectoral response is a viable response to the multi-dimensional problem of women drug use.
Challenges Faced by Female-Students in Engineering-Education
ERIC Educational Resources Information Center
Madara, Diana Starovoytova; Cherotich, Sharon
2016-01-01
Gender-related challenges in learning technical courses are universal phenomenon. These challenges could restrain female students from achieving their fullest potential. The main focus of this study, therefore, is to examine self-recognized challenges faced by undergraduate female students in pursuing engineering at the School of Engineering…
ERIC Educational Resources Information Center
Silvernail, David L.; Linet, Sarah R.
2014-01-01
The goal of this study was to: (1) identify challenges faced by Maine school districts in providing high quality public education; (2) describe the magnitude of the challenges; and (3) identify areas where school districts were experiencing some success in meeting these challenges. The School Districts Challenge Survey was distributed online to…
Salas-Zapata, Leonardo; Palacio-Mejía, Lina Sofía; Aracena-Genao, Belkis; Hernández-Ávila, Juan Eugenio; Nieto-López, Emmanuel Salvador
To estimate the direct costs related to hospitalizations for diabetes mellitus and its complications in the Mexican Institute of Social Security METHODS: The hospital care costs of patients with diabetes mellitus using diagnosis-related groups in the IMSS (Mexican Institute of Social Security) and the hospital discharges from the corresponding E10-E14 codes for diabetes mellitus were estimated between 2008-2013. Costs were grouped according to demographic characteristics and main condition, and were estimated in US dollars in 2013. 411,302 diabetes mellitus discharges were recorded, representing a cost of $1,563 million. 52.44% of hospital discharges were men and 77.26% were for type 2 diabetes mellitus. The biggest cost was attributed to peripheral circulatory complications (34.84%) and people from 45-64 years of age (47.1%). Discharges decreased by 3.84% and total costs by 1.75% in the period analysed. The complications that caused the biggest cost variations were ketoacidosis (50.7%), ophthalmic (22.6%) and circulatory (18.81%). Hospital care for diabetes mellitus represents an important financial challenge for the IMSS. The increase in the frequency of hospitalisations in the productive age group, which affects society as a whole, is an even bigger challenge, and suggests the need to strengthen monitoring of diabetics in order to prevent complications that require hospital care. Copyright © 2016 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.
Comparison of algorithms for the detection of cancer-drivers at sub-gene resolution
Porta-Pardo, Eduard; Kamburov, Atanas; Tamborero, David; Pons, Tirso; Grases, Daniela; Valencia, Alfonso; Lopez-Bigas, Nuria; Getz, Gad; Godzik, Adam
2018-01-01
Understanding genetic events that lead to cancer initiation and progression remains one of the biggest challenges in cancer biology. Traditionally most algorithms for cancer driver identification look for genes that have more mutations than expected from the average background mutation rate. However, there is now a wide variety of methods that look for non-random distribution of mutations within proteins as a signal they have a driving role in cancer. Here we classify and review the progress of such sub-gene resolution algorithms, compare their findings on four distinct cancer datasets from The Cancer Genome Atlas and discuss how predictions from these algorithms can be interpreted in the emerging paradigms that challenge the simple dichotomy between driver and passenger genes. PMID:28714987
Challenges Facing Teachers New to Working in Schools Overseas
ERIC Educational Resources Information Center
Halicioglu, Margaret L.
2015-01-01
This article considers the potential challenges facing teachers moving abroad for the first time, both professional challenges in their school and personal challenges in their private life. It suggests that such teachers embarking on a professional adventure overseas would benefit from careful consideration of the kind of school they will thrive…
An Exploration of Challenges Facing Division III Athletic Directors
ERIC Educational Resources Information Center
Engbers, Jeffrey L.
2011-01-01
The purpose of this study was to establish a basic understanding of the challenges associated with directing athletic programs at NCAA Division III Institutions. Specifically, this study identified the frequency, intensity, and time allocated to common challenges facing the position of the NCAA Division III AD. The challenges were examined using…
The Challenges Facing School Governing Bodies in England: A "Perfect Storm"?
ERIC Educational Resources Information Center
James, Chris; Brammer, Steve; Connolly, Michael; Spicer, David Eddy; James, Jane; Jones, Jeff
2013-01-01
The governing bodies of publicly funded schools in England are currently facing a number of substantive challenges of various kinds. Many of the challenges are long-standing, while others relate to the current context for governing wrought by recent education policy developments initiated by central government. A number of the challenges are…
Effects of Biggest Loser exercise depictions on exercise-related attitudes.
Berry, Tanya R; McLeod, Nicole C; Pankratow, Melanie; Walker, Jessica
2013-01-01
To examine whether participants who watched an exercise-related segment of The Biggest Loser television program would have different explicit and implicit affective exercise-related attitudes than those of control participants. University students (N=138) watched a clip of The Biggest Loser or American Idol, then completed a Go/No-go Association Task, a thought-listing task, and questionnaires measuring explicit attitudes, activity level, and mood. Participants who watched The Biggest Loser had significantly lower explicit, but not implicit, attitudes towards exercise than did control participants. There is a need to examine the influence of popular media depictions of exercise.
A PIECE OF THE SPACE SHUTTLE CHALLENGER WASHED ASHORE AT COCOA BEACH
NASA Technical Reports Server (NTRS)
1996-01-01
A large piece of debris from the Space Shuttle orbiter Challenger washes up on Cocoa Beach near the Coconuts on the Beach restaurant and bar almost 11 years after Challenger exploded shortly after liftoff from KSC's Launch Pad 39B. The piece, about 15 feet by 6 feet, is believed to be part of an elevon or rudder. It is one of the biggest pieces to wash ashore to date. A smaller piece also was found Tuesday several blocks south. NASA recovered thousands of pounds of debris from the Atlantic Ocean after the Jan. 28, 1986 accident; about 50 percent of the orbiter remained in the ocean after search operations were suspended. The previously retrieved remains are stored at Cape Canaveral Air Station, mostly in two Minutemen silos. The two newly recovered pieces will be brought to KSC's Security Patrol Headquarters on Contractor Road for examination, documentation and temporary storage.
Challenges of International Students in a Japanese University: Ethnographic Perspectives
ERIC Educational Resources Information Center
Lee, Ju Seong
2017-01-01
The author investigates what challenges four international students (Vietnamese, Filipino, Brazilian, and Chinese) faced and how they coped with these dilemmas in a Japanese language program during the first semester in 2014. Multiple apparatuses (e.g., field notes, face-to-face oral interviews, focal group conversations, and semi-structured…
NASA Astrophysics Data System (ADS)
Seyfried, M. S.; Flerchinger, G. N.; Link, T. E.; McNamara, J. P.
2016-12-01
Vegetation cover and stature in semiarid regions are highly sensitive to variations in evaporative demand and precipitation. Where the terrain is complex, this may result in a spatial mosaic of vegetation cover related to topographically induced variations in solar radiation and hence evaporative demand. The associated energy and water fluxes and carbon stocks probably do not scale linearly, but are potentially predictable. Johnston Draw, a small, semiarid, granitic catchment in the Reynolds Creek Experimental Watershed in Idaho, is dominated by steep north and south-facing slopes. Vegetation on North-facing slopes is more complete. We made spatially extensive, periodic measurements of soil temperature (Ts) soil water content (Ws) to establish the spatial variability of those parameters. In addition, we monitored Ts and Ws in profiles to bedrock, snow depth and meteorological parameters at three paired, north- and south-facing slope locations. These data were compared to simulations of water and energy flux calculated using the Simultaneous Heat and Water (SHAW) model. We found dramatic differences in Ts, with the annual average soil temperature about 5 C warmer on south-facing slopes. Differences varied seasonally, with the biggest differences in the summer, exactly out of phase with the solar radiation differences. Each year soils dried to consistent, low values, but the north-facing soils retained water about one month longer, on average, owing mostly to the greater depth, and hence available water, on those soils. Modeling results indicate that water is retained longer in north-facing soils and the differences in Ts are due to differences in soil cover, primarily from the greater density of vegetative cover. These differences appear to have evolved over time as the result of feedbacks between atmospheric forcings and vegetation response, which promote greater carbon accumulations and deeper soil formation.
Muslims in America: Identity, Diversity and the Challenge of Understanding. 2001 Carnegie Challenge.
ERIC Educational Resources Information Center
Afridi, Sam
This paper discusses challenges and opportunities facing Muslims in the United States, where between 5 to 8 million Muslims live (the fastest growing religion in the country). American Muslims face many challenges, and the public has little understanding of the teachings and practice of Islam. Muslims are prone to negative stereotypes, ethnic…
Abubakar, Amina; Van de Vijver, Fons J R; Fischer, Ronald; Hassan, Amin S; K Gona, Joseph; Dzombo, Judith Tumaini; Bomu, Grace; Katana, Khamis; Newton, Charles R
2016-02-29
The upsurge in the uptake of antiretroviral therapy (ART) has led to a significant increase in the survival of vertically acquired HIV infected children, many of whom are currently living into adolescence and early adulthood. However little if anything is known of the lived experiences and the challenges faced by HIV positive adolescents in the African context. We set out to investigate psychosocial challenges faced by HIV infected adolescents on the Kenyan coast. A total of 44 participants (12 HIV-infected adolescents, 7 HIV uninfected adolescents, and 25 key informants) took part in this qualitative study, using individually administered in-depth interviews. A framework approach was used to analyze the data using NVIVO software. We observed that the challenges faced by adolescents in rural Kenya could be placed into six major themes: poverty, poor mental and physical health, the lack of a school system that is responsive to their needs, challenges in how to disclose to peers and family members, high levels of stigma in its various forms, and challenges of medical adherence leading to the need for close monitoring. In this African community, vertically acquired HIV-infected adolescents face a complex set of social, economic and medical challenges. Our study points to the urgent need to develop multisectorial intervention support programmes to fully address these challenges.
Army Communicator. Volume 32, Number 3, Summer 2007
2007-01-01
goal of bringing people from across the Army together to talk about the issues and challenges they are experiencing in the field and try to work out...actually facing the challenges . Each work- shop had a mediator who collected information on issues being faced and suggested solutions to these problems...these possible items that Signal Center actions may be put forth to bring about resolutions to the challenges facing the warfighter in the field. “I
Exploring the challenges faced by polytechnic students
NASA Astrophysics Data System (ADS)
Matore, Mohd Effendi @ Ewan Mohd; Khairani, Ahmad Zamri
2015-02-01
This study aims to identify other challenges besides those already faced by students, in seven polytechnics in Malaysia as a continuation to the previous research that had identified 52 main challenges faced by students using the Rasch Model. The explorative study focuses on the challenges that are not included in the Mooney Problem Checklist (MPCL). A total of 121 polytechnic students submitted 183 written responses through the open questions provided. Two hundred fifty two students had responded from a students' perspective on the dichotomous questions regarding their view on the challenges faced. The data was analysed qualitatively using the NVivo 8.0. The findings showed that students from Politeknik Seberang Perai (PSP) gave the highest response, which was 56 (30.6%) and Politeknik Metro Kuala Lumpur (PMKL) had the lowest response of 2 (1.09%). Five dominant challenges were identified, which were the English language (32, 17.5%), learning (14, 7.7%), vehicles (13, 7.1%), information technology and communication (ICT) (13, 7.1%), and peers (11, 6.0%). This article, however, focus on three apparent challenges, namely, English language, vehicles, as well as computer and ICT, as the challenges of learning and peers had been analysed in the previous MPCL. The challenge of English language that had been raised was regarding the weakness in commanding the aspects of speech and fluency. The computer and ICT challenge covered the weakness in mastering ICT and computers, as well as computer breakdowns and low-performance computers. The challenge of vehicles emphasized the unavailability of vehicles to attend lectures and go elsewhere, lack of transportation service in the polytechnic and not having a valid driving license. These challenges are very relevant and need to be discussed in an effort to prepare polytechnics in facing the transformational process of polytechnics.
Chin, David; Rosenblatt, Alice; Simon, Greg; Lauer, Charles
2007-10-29
The U.S. health system is not sustainable as currently structured--innovation is necessary to fuel reform, according to PricewaterhouseCoopers' report, HealthCast 2020: Creating a Sustainable Health System. But wide-scale innovation--which requires diverse players within the industry to collaborate--is difficult to achieve. In this installment of Straight Talk, leaders from WellPoint, Inc., one of the nation's largest health benefits companies, and FasterCures/The Center for Accelerating Medical Solutions, a think-tank based in Washington, talk about what they're doing to nurture innovation.
NASA Astrophysics Data System (ADS)
Shrestha, Nilam; Shrestha, Sanju
2015-12-01
Nepal is one of the least developed countries in the world, and education has been a major focus of the government. Half of the population is female, and providing education to women has been one of the biggest challenges to the government. Encouraging science education for girls, with a focus on physics, is even more of a Herculean task. Enrollment of girls in higher education is just over 25%. Data from 2002 to mid-2014 shows that the number of women in physics is increasing gradually, although their numbers are still very low.
A Conceptual Model for Analysing Collaborative Work and Products in Groupware Systems
NASA Astrophysics Data System (ADS)
Duque, Rafael; Bravo, Crescencio; Ortega, Manuel
Collaborative work using groupware systems is a dynamic process in which many tasks, in different application domains, are carried out. Currently, one of the biggest challenges in the field of CSCW (Computer-Supported Cooperative Work) research is to establish conceptual models which allow for the analysis of collaborative activities and their resulting products. In this article, we propose an ontology that conceptualizes the required elements which enable an analysis to infer a set of analysis indicators, thus evaluating both the individual and group work and the artefacts which are produced.
Watermarking -- Paving the Way for Better Released Documents
NASA Technical Reports Server (NTRS)
Little, Keith; Carole, Miller; Schwindt, Paul; Zimmerman, Cheryl
2011-01-01
One of the biggest issues with regard to Released Documentation is making sure what you are looking at is. in fact. what you think it is. Is it Released or Not? Is it the Latest? How to be sure? In this brief session, we'll discuss the path Kennedy Space Center has taken in implementing Watermarking with ProductView . We'11 cover the premise, challenges, and implementation from our windchill 9.1 environment. Come join us and see if we can't save you some time and headaches in the long-run.
Challenges and Changes Faced by Rural Superintendents
ERIC Educational Resources Information Center
Lamkin, Marcia L.
2006-01-01
This research study was designed to build grounded theory about the challenges faced by rural superintendents. Participating rural superintendents identified five areas that presented a challenge but that also applied to superintendents in other settings: school law, finance, personnel, government mandates, and district or board policies. Further,…
Dickey, Lore M; Singh, Anneliese A
2017-08-01
This article explores some of the challenges faced by trans and gender diverse (TGD) individuals who not only are attempting to access trans-affirmative care, but who are also members of the very profession from which they are seeking services. The authors explore challenges related to finding supervision, accessing care for assessment services, and finding a provider for personal counseling. With each example, the authors unpack the challenges and also address the implications for training for all involved. Based on these challenges that TGD psychologists and trainees face in attempting to access care, the authors provide recommendations related to trans-affirmative training for psychologists. © 2017 Wiley Periodicals, Inc.
2017-01-01
ABSTRACT The “invisible army” of clinical microbiologists is facing major changes and challenges. The rate of change in both the science and technology is accelerating with no end in sight, putting pressure on our army to learn and adapt as never before. Health care funding in the United States is undergoing dramatic change which will require a new set of assumptions about how clinical microbiology is practiced here. A major challenge facing the discipline is the replacement of a generation of clinical microbiologists. In my opinion, it is incumbent on us in the invisible army to continue to work with the American Society for Microbiology (ASM) in meeting the future challenges faced by our discipline. In this commentary, I will first discuss some recent history of clinical microbiology within ASM and then some current challenges we face. PMID:28659316
Children at Risk: Global Views on Challenges Facing Children
ERIC Educational Resources Information Center
Neugebauer, Roger
2011-01-01
Members of the World Forum community were invited to respond to the question: "What is the most urgent challenge facing young children in your country?" Here are some of their responses. Jamils Richard Achunji Anguaseh mentions that in Cameroon, young children face lots of insecurity, both from health hazards and poor parenting practices. There…
Challenges in the management of community pharmacies in Malaysia
2017-01-01
Background: The provision of professional pharmacy services by community pharmacists continues to be limited, particularly in low and middle income countries. It was postulated that multiple management challenges faced by community pharmacists contribute to this situation. Objective: The primary aim of the research was to determine the challenges faced in the management of community pharmacies in Sarawak (the largest state in Malaysia), and practical strategies to cope and overcome the challenges. Methods: Semi-structured interviews were carried out with community pharmacists practising in Sarawak. Purposive and snowball sampling were employed to ensure a diverse group of informants. The interviews were audio-recorded and transcribed verbatim, with the resultant data analysed using thematic analysis. Data collection, coding, interpretation were carried out iteratively until theoretical saturation. Results: Twenty respondents from different demographic characteristics were recruited. Six major themes were identified. Management challenges faced by community pharmacists traverse five major domains: market competition, legislative issues, customers’ knowledge and expectations, macroeconomic impacts and operational challenges. Most of these challenges require government intervention to be resolved. In the meantime, improving customer service and expanding the range of professional services were seen as the most viable strategies to cope with existing challenges. The main concern is that current legislative and economic landscape may hinder these strategies. Enactment of dispensing separation and more protective measures against market competition were suggested to alleviate the challenges faced. Conclusion: Numerous management challenges faced by community pharmacists that distract them from delivering professional pharmacy services have been highlighted. Urgent affirmative actions by the government are warranted in supporting community pharmacists to realise and maximise their potentials. PMID:28690697
Challenges When Introducing Electronic Exam
ERIC Educational Resources Information Center
Kuikka, Matti; Kitola, Markus; Laakso, Mikko-Jussi
2014-01-01
Time pressures often necessitate the use of more efficient exam tools, such as electronic exams (e-exams), instead of traditional paper exams. However, teachers may face challenges when introducing e-exams in a higher education context. This paper describes what kinds of challenges teachers may face when introducing e-exams, based on experiences…
Bridging the Gap: The Challenges of Employing Entrepreneurial Processes within University Settings
ERIC Educational Resources Information Center
Wardale, Dorothy; Lord, Linley
2016-01-01
In Australia and elsewhere, universities face increasing pressure to improve research output and quality, particularly through partnerships with industry. This raises interesting challenges for academic staff with considerable industry experience who are "new" to academe. Some of these challenges were faced by the authors who have been…
Confronting Unsuccessful Practices: Repositioning Teacher Identities in English Education
ERIC Educational Resources Information Center
Vetter, Amy; Hartman, Shana V.; Reynolds, Jeanie M.
2016-01-01
Teacher education programs attempt to prepare preservice teachers for the various challenges faced in the classroom. One particular challenge new teachers face is how to handle unsuccessful practices. This paper argues that confronting ineffective practices require that teachers respond to complex and dynamic challenges, making change difficult…
Challenges Faced by Project Competition Participants and Recommended Solutions
ERIC Educational Resources Information Center
Demirel, Turgay; Baydas, Ozlem; Yilmaz, Rabia M.; Goktas, Yuksel
2013-01-01
The numbers of project competitions and interest in this kind of competition have been steadily increasing in Turkey. Accordingly, it is important to determine what challenges teachers and students may face while preparing themselves for project competitions, so that recommendations may be made to overcome these challenges. This study investigated…
NASA Astrophysics Data System (ADS)
Islam, S.; Susskind, L.
2012-12-01
Most difficulties in water management are the product of rigid assumptions about how water ought to be allocated in the face of ever-increasing demand and growing uncertainty. When stakeholders face contending water claims, one of the biggest obstacles to reaching agreement is uncertainty. Specifically, there are three types of uncertainty that need to be addressed: uncertainty of information, uncertainty of action and uncertainty of perception. All three shape water management decisions. Contrary to traditional approaches, we argue that management of uncertainty needs to include both risks and opportunities. When parties treat water as a flexible rather than a fixed resource, opportunities to create value can be invented. When they use the right processes and mechanisms to enhance trust, even parties in conflict can reach agreements that satisfy their competing water needs and interests simultaneously. Using examples from several boundary crossing water cases we will show how this balance between risks and opportunities can be found to manage water resources for an uncertain future.
Housing preferences of young adults in Indonesia: housing attributes and consequences
NASA Astrophysics Data System (ADS)
Farasa, N.; Kusuma, H. E.
2018-03-01
Nowadays, the housing demand of young adults in Indonesia is important issues for the sustainable development of the market. Facing differences of life phases, such as marriage, leaving home after graduation, and new job positioning, young adults become the main segment facing constant housing choice decisions in the housing market. In their particular phase of life, young adults have distinct preferences for housing attributes which bring a great influence on their lives in the future. Data was gathered from a survey questionnaire that was answered by 180 young adults in Indonesia, ranging from age 22-33 years. The findings suggest that the green area and view, location, simplicity, home design, and accessibility are the significant parts as housing attributes for young adults’ housing preferences in Indonesia. The effect of these attributes has many consequences such as security, personalization, mood/ambiance, maintenance, interaction, image, flexibility, environmental, economy, durability, convenience, comfort, and circulation. The biggest group of young adults who prefer comfort as their wanted consequences tend to have high preferences on housing attributes of the green area and view, and simplicity.
Nakamura, Mio; Asaba, Akie; Kottorp, Anders
2017-01-01
Background Occupational therapists sometimes find it challenging to integrate client-centered and occupational therapy specific assessments in practice. The aim of this study was to explore the use of occupational therapy specific assessments such as the Assessment of Motor and Process Skills (AMPS) among occupational therapists in Sweden and Japan. Methods Interviews and qualitative thematic analyses were utilized. Findings Four themes are reported: (1) use it or lose it, (2) simply no space until after hours, (3) biggest barriers can be colleagues, and (4) being more specific: communication. Conclusion In keeping with previous studies, occupational therapists often find it challenging to implement client-centered and occupation-based assessment tools into practice. However, more work is needed to understand how best practices can be incorporated into a changing occupational therapy daily practice. PMID:29333112
Hosting a CUWiP - the fun and the challenges
NASA Astrophysics Data System (ADS)
Gaarde, Mette
2014-03-01
Louisiana State University is hosting the South Eastern Conference for Undergraduate Women in Physics (CUWiP) in January 2014, as one out of eight regional CUWiPs. As a first-time organizer of a CUWiP I will share our local experiences with organizing and hosting the conference: the timeline for the work that is involved in hosting, what we learned, and what were our biggest successes and challenges. Since the different regional conferences have different ``flavors'' and somewhat different issues, I will also briefly give an overview of the more general lessons learned with highlights from some of the different conferences. Finally, I will try to convey the incredibly empowering experience, for both organizers and participants, of being in a room with more than 100 female physicists!
ERIC Educational Resources Information Center
Paquette, Paige Fuller
2009-01-01
There is much literature addressing challenges face-to-face freshman composition instructors encounter in developing college courses that foster critical thinking skills crucial to developing written argument. Composition instructors may face challenges in teaching students that writing is a means of making meaning, there are many different…
The Challenges of Adopting the Learning Organisation Philosophy in a Singapore School
ERIC Educational Resources Information Center
Retna, Kala S.; Tee, Ng Pak
2006-01-01
Purpose: To report on a case study that examines how the Learning Organisation (LO) concept can be applied in a Singapore school and the challenges that the school faces in the process. Design/methodology/approach: A qualitative research inquiry was adopted using ethnographic methods. Data includes in-depth face-to-face interviews, observation of…
Challenges Faced by Undergraduate Military Students at American Public University System
ERIC Educational Resources Information Center
Machuca, Ana; Torres, Karin; Morris, Pamela; Whitley, William
2014-01-01
This paper will summarize some of challenges faced by military students enrolled in an associate and bachelors online program at American Public University System (APUS). The survey results on which the study is based exposed the following problems faced by military personnel: 48.7% had difficulties working around military obligations, 33.3%…
ERIC Educational Resources Information Center
Hakami, Samah Mohammed
2012-01-01
The purpose of this study was to explore the major acculturation challenges faced by Saudi female students who study in the U.S. and to develop a scale to measure potential acculturation challenges. The construction of the scale was based on a table of specification that included nine domains of possible acculturation challenges: (a)…
NASA Astrophysics Data System (ADS)
García Moreno, R.; Gameda, S.; Diaz Alvarez, M. C.; Selasie, Y. G.
2012-04-01
Agriculture in Ethiopia is one of first priority since close to 10 In this context, the Ethiopian crop production faces to the following soil management challenges: lack of updated soil data, macro and micro nutrient depletion, acidity, salinity and soil surface erosion and crusting. One of the biggest issues is the loss of arable land, above 137 T/yr, reaching during some particularly dried periods until 300 T/yr. In this context, the authors constituted a working group of experts from Spanish and Ethiopian universities, local producers and international and governmental organisms to analyse the problems related to the different agro ecological zones found in Ethiopia and the management practices of different local producers. The study produced the trends to implement in the different areas to improve soil management practices in order to contribute to increase the crop production mainly to achieve food security problems. The analyse produced different working fields for the next years for addressing soil degradation, improving land resources management practices, increasing agricultural productivity, updating the available soil data, developing an international program of education, transferring of knowledge from similar study cases and implementing economical tools to help producers to assure income after severe edapho-climatic events. The practical work and the projects developed for the next period is addressed to smallholder farms belonging to the different 34 agro ecological zones identified in Ethiopia, each of them with very specific environmental, cultural and soil management practices.
Hospital all-risk emergency preparedness in Ghana.
Norman, I D; Aikins, M; Binka, F N; Nyarko, K M
2012-03-01
This paper assessed the emergency preparedness programs of health facilities for all-risks but focused on Road Traffic Accidents, (RTA) resulting in surge demand. It adopted W. H. O checklist covering hospital preparedness, equipment, manpower and surge capacity planning as best practices for the mitigation of public health emergencies. This is a cross-sectional study of purposively selected health facilities. The method used consisted of site visit, questionnaire survey, literature and internet review. The W. H. O. standard for emergency preparedness of health facilities was used to evaluate and assess the nation's hospitals surge capacity programs. The study was conducted between March-June, 2010. A total of 22 district and regional health facilities including teaching hospitals participated in the study. All 10 regions of the country were covered. These were: (1) many of the nation's hospitals were not prepared for large RTA's resulting in surge demands, and did not possess general emergency preparedness programs. (2) The hospitals' respective abilities to handle large scale RTA's were compromised by the lack of competent medical and allied health personnel and adequate supplies. The inadequacies of the hospital system in responding to emergencies raise serious public health concerns. The biggest challenge facing the hospitals in their emergency intervention is the lack of pre-emergency and emergency preparedness plans as well as the coordination of the hospitals response mechanisms. The paper ended with recommendations on how the nation's hospitals and their supervisory agencies could improve emergency preparedness.
In Vitro Antimicrobial Potential of the Lichen Parmotrema sp. Extracts against Various Pathogens.
Chauhan, Ritika; Abraham, Jayanthi
2013-07-01
The ongoing increasing antibiotic resistance is one of the biggest challenges faced by global public health. The perennial need for new antimicrobials against a background of increasing antibiotic resistance in pathogenic and opportunistic microorganisms obliges the scientific community to constantly develop new drugs and antimicrobial agents. Lichens are known prolific sources of natural antimicrobial drugs and biologically active natural products. This study was aimed to explore in vitro antimicrobial activity of lichen Parmotrema sp. The methanol and aqueous extracts of lichen Parmotrema sp. was extracted using Soxhlet extractor. Antibiotic assessment of methanol and aqueous extracts was done against eight bacterial (Escherichia coli, Staphylococcus aureus, Proteus mirabilis, Salmonella sp., Shigella sp., Enterococci faecalis, Pseudomonas aeruginosa, Klebsiella pneumoniae,) clinical pathogens and five plant pathogenic fungal strains (Aspergillus terreus strain JAS1, Scedosporium sp. JAS1, Ganoderma sp. JAS4, Candida tropicalis and Fusarium sp.) by Kirby-Bauer method. The methanol lichen Parmotrema sp. extract inhibited all the test organisms. The highest antibacterial activity was found against Pseudomonas aeruginosa and Staphylococcus aureus. The weakest activity was manifested in Salmonella sp. and Scedosporium sp. JAS1. Strong antifungal effect was found against Ganoderma sp. JAS4 and Fusarium sp. The aqueous lichen Parmotrema sp. extract revealed neither antibacterial nor antifungal activity. The present study shows that tested lichen Parmotrema sp. extracts demonstrated a strong antimicrobial effect. That suggests the active components from methanol extracts of the investigated lichen Parmotrema sp. can be used as natural antimicrobial agent against pathogens.
The value of mentorship in medical education.
Dalgaty, Faith; Guthrie, Greg; Walker, Heather; Stirling, Kevin
2017-04-01
The transition from senior medical student to working safely and effectively as a new junior doctor is one of the biggest challenges that a new graduate will face. In 2014 the General Medical Council published The state of medical education and practice in the UK, reporting that some new doctors continue to struggle with increased responsibilities. We classify these instances as a 'performance gap', describing occasions in clinical practice where an individual exceeds their performance capacity. The Medical Mentorship Programme addressed identified performance gaps through a structured curriculum of simulation-based education and facilitated clinical practice. Programme content was based on the experiences of the authors and their peers in graduating from their undergraduate training programme and becoming junior doctors. A questionnaire was disseminated to junior doctors in their first clinical rotation. The questionnaire asked doctors to describe instances where they experienced a performance gap. These data informed the development of the Medical Mentorship Programme. The effect of this programme was then evaluated via focus group discussion. The Medical Mentorship Programme has been shown to be an effective conduit for supporting the transfer of learning needed to address performance gaps in students. The programme increased the confidence of students in preparation for clinical practice and allowed junior doctors to reflect on their professional development. The programme combined complementary teaching techniques - mentorship, simulation and direct clinical experience - to aid the professional development of both students and mentors. Some new doctors continue to struggle with increased responsibilities. © 2016 John Wiley & Sons Ltd.
Lenton, Samuel; Walsh, Danielle L; Rhys, Natasha H; Soper, Alan K; Dougan, Lorna
2016-07-21
Halophilic organisms have adapted to survive in high salt environments, where mesophilic organisms would perish. One of the biggest challenges faced by halophilic proteins is the ability to maintain both the structure and function at molar concentrations of salt. A distinct adaptation of halophilic proteins, compared to mesophilic homologues, is the abundance of aspartic acid on the protein surface. Mutagenesis and crystallographic studies of halophilic proteins suggest an important role for solvent interactions with the surface aspartic acid residues. This interaction, between the regions of the acidic protein surface and the solvent, is thought to maintain a hydration layer around the protein at molar salt concentrations thereby allowing halophilic proteins to retain their functional state. Here we present neutron diffraction data of the monomeric zwitterionic form of aspartic acid solutions at physiological pH in 0.25 M and 2.5 M concentration of potassium chloride, to mimic mesophilic and halophilic-like environmental conditions. We have used isotopic substitution in combination with empirical potential structure refinement to extract atomic-scale information from the data. Our study provides structural insights that support the hypothesis that carboxyl groups on acidic residues bind water more tightly under high salt conditions, in support of the residue-ion interaction model of halophilic protein stabilisation. Furthermore our data show that in the presence of high salt the self-association between the zwitterionic form of aspartic acid molecules is reduced, suggesting a possible mechanism through which protein aggregation is prevented.
DOE Office of Scientific and Technical Information (OSTI.GOV)
MacDonald, Douglas G.; Clements, Samuel L.; Patrick, Scott W.
Securing high value and critical assets is one of the biggest challenges facing this nation and others around the world. In modern integrated systems, there are four potential modes of attack available to an adversary: • physical only attack, • cyber only attack, • physical-enabled cyber attack, • cyber-enabled physical attack. Blended attacks involve an adversary working in one domain to reduce system effectiveness in another domain. This enables the attacker to penetrate further into the overall layered defenses. Existing vulnerability assessment (VA) processes and software tools which predict facility vulnerabilities typically evaluate the physical and cyber domains separately. Vulnerabilitiesmore » which result from the integration of cyber-physical control systems are not well characterized and are often overlooked by existing assessment approaches. In this paper, we modified modification of the timely detection methodology, used for decades in physical security VAs, to include cyber components. The Physical and Cyber Risk Analysis Tool (PACRAT) prototype illustrates an integrated vulnerability assessment that includes cyber-physical interdependencies. Information about facility layout, network topology, and emplaced safeguards is used to evaluate how well suited a facility is to detect, delay, and respond to attacks, to identify the pathways most vulnerable to attack, and to evaluate how often safeguards are compromised for a given threat or adversary type. We have tested the PACRAT prototype on critical infrastructure facilities and the results are promising. Future work includes extending the model to prescribe the recommended security improvements via an automated cost-benefit analysis.« less
A Bioengineered Nisin Derivative to Control Biofilms of Staphylococcus pseudintermedius
Field, Des; Gaudin, Noémie; Lyons, Francy; O'Connor, Paula M.; Cotter, Paul D.; Hill, Colin; Ross, R. Paul
2015-01-01
Antibiotic resistance and the shortage of novel antimicrobials are among the biggest challenges facing society. One of the major factors contributing to resistance is the use of frontline clinical antibiotics in veterinary practice. In order to properly manage dwindling antibiotic resources, we must identify antimicrobials that are specifically targeted to veterinary applications. Nisin is a member of the lantibiotic family of antimicrobial peptides that exhibit potent antibacterial activity against many gram-positive bacteria, including human and animal pathogens such as Staphylococcus, Bacillus, Listeria, and Clostridium. Although not currently used in human medicine, nisin is already employed commercially as an anti-mastitis product in the veterinary field. Recently we have used bioengineering strategies to enhance the activity of nisin against several high profile targets, including multi-drug resistant clinical pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) and also against staphylococci and streptococci associated with bovine mastitis. However, newly emerging pathogens such as methicillin resistant Staphylococcus pseudintermedius (MRSP) pose a significant threat in terms of veterinary health and as a reservoir for antibiotic resistance determinants. In this study we created a nisin derivative with enhanced antimicrobial activity against S. pseudintermedius. In addition, the novel nisin derivative exhibits an enhanced ability to impair biofilm formation and to reduce the density of established biofilms. The activities of this peptide represent a significant improvement over that of the wild-type nisin peptide and merit further investigation with a view to their use to treat S. pseudintermedius infections. PMID:25789988
New portable pipe wall thickness measuring technique
NASA Astrophysics Data System (ADS)
Pascente, Joseph E.
1998-03-01
One of the biggest inspection challenges facing many of the process industries; namely the petrochemical, refining, fossil power, and pulp and paper industries is: How to effectively examine their insulated piping? While there are a number of failure mechanisms involved in various process piping systems, piping degradation through corrosion and erosion are by far the most prevalent. This degradation can be in the form of external corrosion under insulation, internal corrosion through a variety of mechanisms, and internal erosion caused by the flow of the product through the pipe. Refineries, chemical plants and electrical power plants have MANY thousands of miles of pipe that are insulated to prevent heat loss or heat absorption. This insulation is often made up of several materials, with calcium based material being the most dense. The insulating material is usually wrapped with an aluminum or stainless steel outer wrap. Verification of wall thickness of these pipes can be accomplished by removing the insulation and doing an ultrasound inspection or by taking x- rays at a tangent to the edge of the pipe through the insulation. Both of these processes are slow and expensive. The time required to obtain data is measured in hours per meter. The ultrasound method requires that the insulation be plugged after the inspection. The surface needs to be cleaned or the resulting data will not be accurate. The tangent x-ray only shows two thicknesses and requires that the area be roped off because of radiation safety.
Emerging roles for biomedical librarians: a survey of current practice, challenges, and changes.
Crum, Janet A; Cooper, I Diane
2013-10-01
This study is intended to (1) identify emerging roles for biomedical librarians and determine how common these roles are in a variety of library settings, (2) identify barriers to taking on new roles, and (3) determine how librarians are developing the capacity to take on new roles. A survey was conducted of librarians in biomedical settings. Most biomedical librarians are taking on new roles. The most common roles selected by survey respondents include analysis and enhancement of user experiences, support for social media, support for systematic reviews, clinical informationist, help for faculty or staff with authorship issues, and implementation of researcher profiling and collaboration tools. Respondents in academic settings are more likely to report new roles than hospital librarians are, but some new roles are common in both settings. Respondents use a variety of methods to free up time for new roles, but predominant methods vary between directors and librarians and between academic and hospital respondents. Lack of time is the biggest barrier that librarians face when trying to adopt new roles. New roles are associated with increased collaboration with individuals and/or groups outside the library. This survey documents the widespread incorporation of new roles in biomedical libraries in the United States, as well as the barriers to adopting these roles and the means by which librarians are making time for them. The results of the survey can be used to inform strategic planning, succession planning, library education, and career development for biomedical librarians.
Challenges for Novice School Leaders: Facing Today's Issues in School Administration
ERIC Educational Resources Information Center
Beam, Andrea P.; Claxton, Russell L.; Smith, Samuel J.
2016-01-01
Challenges for novice school leaders evolve as information is managed differently and as societal and regulatory expectations change. This study addresses unique challenges faced by practicing school administrators (n = 159) during their first three years in a school leadership position. It focuses on their perceptions, how perceptions of present…
Leading Schools Facing Challenging Circumstances: Some Insights from Western Australia
ERIC Educational Resources Information Center
Gillett, Jonathan; Clarke, Simon; O'Donoghue, Tom
2016-01-01
This paper examines leadership strategies that are most likely to engender success in schools that may be defined as facing challenging circumstances. First, it presents an overview of the relevant literature in order to illustrate distinctive challenges that tend to be encountered in these environments, as well as strategies that are adopted for…
ERIC Educational Resources Information Center
Fortuin, Karen P. J.; van Koppen, C. S. A.; Leemans, Rik
2011-01-01
Conceptual models are useful for facing the challenges of environmental sciences curriculum and course developers and students. These challenges are inherent to the interdisciplinary and problem-oriented character of environmental sciences curricula. In this article, we review the merits of conceptual models in facing these challenges. These…
CAEP Challenges for a Mid-South U.S. College Teacher Education Program
ERIC Educational Resources Information Center
Moffett, David W.
2016-01-01
What are the challenges faced by a mid-south liberal arts college teacher education program, in its attempt to successfully meet the new Council for the Accreditation of Educator Preparation (CAEP) accreditation requirements? The Investigator studied the Educator Program Provider (EPP) during academic year 2015-2016. The challenges faced by the…
Challenges of Attending E-Learning Studies in Nigeria
ERIC Educational Resources Information Center
Bugi, Stephan Z.
2012-01-01
This study set out to find out what challenges the E-leaner faces in the Nigerian environment. Survey research design was used to obtain the opinion of 200 randomly selected E-learners in Kaduna metropolis. Their responses revealed that the most prominent challenges they face are, Inadequate Power supply, Internet connectivity problems, Efficacy…
ERIC Educational Resources Information Center
Markham, Paul L.; Gordon, Karen E.
2007-01-01
For English Language Learners (ELLs), the process of becoming literate in English is daunting. Not only are these students faced with the same literacy challenges faced by native English-speaking students, but they are also challenged with extensive diversity issues relating to substantial differences in linguistic, cultural, and academic…
Young persons with visual impairment: challenges of participation.
Salminen, Anna-Liisa; Karhula, Maarit E
2014-07-01
To describe the challenges to activity and participation faced by young people with visual impairment within the framework of the International Classification of Functioning (ICF). 14 young persons (aged 16-22 years) with visual impairment and their parents (n = 22) participated in the study. The Canadian Occupational Performance Measure (COPM) was used to describe challenges of participation as perceived by the young persons themselves. Individual interviews with the young persons and their parents were used to investigate in more depth the challenges the young persons face with regard to participation. Young persons with visual impairment face challenges to participation most frequently with regard to mobility, domestic life, interpersonal interaction and relationships, major life areas, and leisure activities. The environment in which they live has a central role as a barrier or facilitator of participation. The challenges related to activities and participation that young persons with visual impairment face are diverse. It is important that these challenges are assessed individually and with the help of subjective measures. Serving as a broad framework for classifying the data, the ICF proved to be a useful tool, but used strictly at category level it may limit the coding of data and narrow interpretation.
Horton-Deutsch, Sara; Young, Patricia K; Nelson, Kristine A
2010-05-01
The aim of the present study was to explore the experience of becoming a nurse faculty leader. In a recent interpretation of 23 interviews conducted with nurse faculty leaders from across the United States about their experiences of becoming a leader three themes were identified: being thrust into leadership, taking risks and facing challenges. This interpretive phenomenological study further explicates three aspects of how nurse educators faced challenges in becoming and serving as a leader. Facing challenges meant reflecting, persevering through difficulties and learning to relate to others in new ways. Exemplars of participant experiences are provided for concreteness, to assist readers in determining how findings resonate with their own experience and how they can actualize this resonance in their own leadership practice. In the present study, reflecting, persevering through difficulties and learning to relate with others in a new way was how leaders faced challenges. Leadership development opportunities that facilitate self-exploration, caring and thoughtful interactions with others and values clarification serve as the foundation for becoming a nurse faculty leader who is, in turn, able to build leadership capacity in other individuals and organizations.
Focusing a Transition: Challenges Facing the New Administration
2016-09-01
FOCUSING A TRANSITION Challenges Facing the New Administration A Report by the Defense Business Board 2016 This report, DBB Report FY16-5, is a ...Facing the New Administration A Report by the Defense Business Board 5 Table of Contents INTRODUCTION...While reviewing the budget, the team should develop a list of items to propose for immediate termination. The Board offers the following
2007-09-01
Office Why GAO Did This Study Highlights Accountability Integrity Reliability September 2007 DEFENSE INFRASTRUCTURE Challenges Increase Risks for...authority to conduct evaluations on his own initiative. It addresses (1) the challenges and associated risks the Army faces in providing for timely...but it faces several complex implementation challenges that risk late provision of needed infrastructure to adequately support incoming personnel
A qualitative exploration of the major challenges facing pharmacovigilance in Saudi Arabia.
Aljadhey, Hisham; Mahmoud, Mansour A; Alshammari, Thamir M; Al-Dhaeefi, Mohammed; Le Louet, Herve; Perez-Gutthann, Susana; Pitts, Peter J
2015-09-01
To explore the challenges facing pharmacovigilance in Saudi Arabia and formulate recommendations to improve it from the perspective of healthcare professionals in Saudi Arabia. This was a qualitative study of 4 focus group discussions with pharmacists, physicians, and academicians held under the auspices of the King Saud University School of Pharmacy and the Center for Medicine in the Public Interest, Riyadh, Saudi Arabia. A total of 29 eligible healthcare professionals were invited to participate in the discussion. The predefined themes of the study were the current practice and major challenges facing pharmacovigilance in regulatory bodies, hospitals, the community, and academia, as well as recommendations to improve pharmacovigilance practice. Of the 29 participants invited, 27 attended the discussion. Challenges facing regulatory bodies included complicated adverse drug reactions (ADR) reporting forms, lack of feedback on ADRs submitted to the Saudi Food and Drug Authority, lack of decisions from the local authority to withdraw medications, and lack of data on pharmacovigilance. The challenges to pharmacovigilance in hospitals included the lack of knowledge of the significance of ADR reporting, workload, blaming culture, and lack of collaboration between regulatory bodies and hospitals. However, challenges facing pharmaceutical industries included the lack of drug manufacturers in Saudi Arabia and lack of interest in pharmacovigilance. Recommendations to improve pharmacovigilance included the need for communication, stronger regulatory requirements, the need for research, the need for unified ADRs reporting, and continuous education and training. The study has identified the challenges facing pharmacovigilance in Saudi Arabia and made certain recommendations to overcome them. These recommendations might be helpful for regulatory bodies to enhance spontaneous reporting and promote pharmacovigilance.
Gosselt, Jordy F; Strump, Tanja; Van Hoof, Joris
2016-12-01
Based on the existing literature, relevant determinants of availability for on-premises locations, off-premises locations, and the Internet were qualitatively explored and categorized by "experts" consisting of underage alcohol purchasers. In total, 14 focus group discussions were conducted with 94 Dutch adolescents. For on-premises locations, the high prices were perceived as the biggest disadvantage, and the ease to circumvent legal age limits as the biggest advantage. For off-premises locations, the cheap pricing was perceived as the most positive aspect, and the legal age limit as the biggest disadvantage. For online purchases, the waiting time was perceived as the most negative aspect, and the proximity of online stores as the biggest advantage. © The Author(s) 2015.
Finding Erich Jantsch's Five Crucial Innovations: A Study of Four Small Colleges
ERIC Educational Resources Information Center
MacVie, Leah
2017-01-01
Institutions of higher education have faced many challenges over the last few decades. Though many large institutions have the resources needed to respond to these challenges, small institutions have had to be innovative in the ways in which they are adapting. There are similarities between the external challenges that institutions face today and…
The Challenges Faced by Chinese Higher Education as It Expands in Scale
ERIC Educational Resources Information Center
Xiaohao, Ding
2004-01-01
This article reports the challenges faced by Chinese higher education as it expands in scale. The scale of China's higher education has seen unprecedented expansion in recent years. This article explores the new opportunities and challenges that such expansion brings to China's higher education. The author states that, aside from the many…
Reflecting on the Challenges of Applied Theatre in Kenya
ERIC Educational Resources Information Center
Okuto, Maxwel; Smith, Bobby
2017-01-01
In this article the authors draw on their own experience and research in applied theatre in Kenya in order to reflect on challenges currently facing practitioners working in the country. In order to outline the range of challenges faced by practitioners, issues related to the wider landscapes of government and politics in Kenya are explored,…
Special Education in Rural Schools: Why Less Takes More
ERIC Educational Resources Information Center
Bouck, Emily C.; Albaugh, Diane; Bouck, Mary K.
2005-01-01
Everyone can understand the challenges teachers face in organizing and supervising field trips, challenges that are even greater when the students have special needs and live in poverty. But how daunting, the authors ask, are the challenges these students face every day? Very few people who have never tried it are truly aware of all the…
International Graduate Students' Academic Writing Practices in Malaysia: Challenges and Solutions
ERIC Educational Resources Information Center
Singh, Manjet Kaur Mehar
2015-01-01
This article focuses on the challenges faced by non-native English speaking international graduate students in their academic writing practices while they studied at a university in Malaysia as well as the solutions they employed when faced with the challenges. Academic Literacies Questionnaire was used to collect data. Based on 131 participants,…
A Content Analysis Concerning the Studies on Challenges Faced by Novice Teachers
ERIC Educational Resources Information Center
Kozikoglu, Ishak
2017-01-01
The purpose of this research is to analyze the studies concerning challenges faced by novice teachers in terms of various aspects and compare challenges according to location of the studies conducted in Turkey and abroad. A total of 30 research studies were included in detailed analysis. This is a descriptive study based on qualitative research…
Mentoring Matters: The Challenge for Teacher Education
ERIC Educational Resources Information Center
McCann, Thomas M.; Ed.; Johannessen, Larry, Ed.
2009-01-01
Beginning teachers face many challenges and difficulties; as a result, one-third will leave the profession in the first three years and nearly half will be gone within their first five years in the profession. The challenge facing university teacher education programs is to fix the hole in the bottom of the bucket and find strategic new ways to…
NASA Astrophysics Data System (ADS)
Salva-Catarineu, Montserrat; Salvador-Franch, Ferran; Lopez-Bustins, Joan A.; Padrón-Padrón, Pedro A.; Cortés-Lucas, Amparo
2016-04-01
The current extent of Juniperus turbinata in the island of El Hierro is very small due to heavy exploitation for centuries. The recovery of its natural habitat has such a high environmental and scenic interest since this is a protected species in Europe. The study of the environmental factors that help or limit its recovery is indispensable. Our research project (JUNITUR) studied the populations of juniper woodlands in El Hierro from different environments. These environments are mainly determined by their altitude and exposure to north-easterly trade winds. The main objective of this study was to compare the thermohygrometric conditions of three juniper woodlands: La Dehesa (north-west face at 528 m a.s.l.), El Julan (south face at 996 m a.s.l.) and Sabinosa (north face at 258 m a.s.l.). They are located at different altitude and orientation in El Hierro and present different recovery rates. We used air sensor data loggers fixed to tree branches for recording hourly temperature and humidity data in the three study areas. We analysed daily data of three annual cycles (from September 2012 to August 2015). Similar thermohygrometric annual cycles among the three study areas were observed. We detected the largest differences in winter temperature and summer humidity between the north (to windward) (Sabinosa and La Dehesa) and south (to leeward) (El Julan) faces of the island. The juniper woodland with a highest recovery rate (El Julan) showed the most extreme temperature conditions in both winter and summer seasons. The results of this project might contribute to the knowledge of the juniper bioclimatology in El Hierro, where there is the biggest population of Juniperus turbinata throughout the Canary Islands.
Validation of the PASSPORT V2 training environment for arthroscopic skills.
Stunt, J J; Kerkhoffs, G M M J; Horeman, T; van Dijk, C N; Tuijthof, G J M
2016-06-01
Virtual reality simulators used in the education of orthopaedic residents often lack realistic haptic feedback. To solve this, the (Practice Arthroscopic Surgical Skills for Perfect Operative Real-life Treatment) PASSPORT simulator was developed, which was subjected to fundamental changes: improved realism and user interface. The purpose was to demonstrate its face and construct validity. Thirty-one participants were divided into three groups having different levels of arthroscopic experience. Participants answered questions regarding general information and the outer appearance of the simulator for face validity. Construct validity was assessed with one standardized navigation task, which was timed. Face validity, educational value and user-friendliness were determined with two representative exercises and by asking participants to fill out the questionnaire. A value of 7 or greater was considered sufficient. Construct validity was demonstrated between experts and novices. Median task time for the fifth trial was 55 s (range 17-139 s) for the novices, 33 s (range 17-59 s) for the intermediates, and 26 s (range 14-52 s) for the experts. Median task times of three trials were not significantly different between the novices and intermediates, and none of the trials between intermediates and experts. Face validity, educational value and user-friendliness were perceived as sufficient (median >7). The presence of realistic tactile feedback was considered the biggest asset of the simulator. Proper preparation for arthroscopic operations will increase the quality of real-life surgery and patients' safety. The PASSPORT simulator can assist in achieving this, as it showed construct and face validity, and its physical nature offered adequate haptic feedback during training. This indicates that PASSPORT has potential to evolve as a valuable training modality.
Scientific Datasets: Discovery and Aggregation for Semantic Interpretation.
NASA Astrophysics Data System (ADS)
Lopez, L. A.; Scott, S.; Khalsa, S. J. S.; Duerr, R.
2015-12-01
One of the biggest challenges that interdisciplinary researchers face is finding suitable datasets in order to advance their science; this problem remains consistent across multiple disciplines. A surprising number of scientists, when asked what tool they use for data discovery, reply "Google", which is an acceptable solution in some cases but not even Google can find -or cares to compile- all the data that's relevant for science and particularly geo sciences. If a dataset is not discoverable through a well known search provider it will remain dark data to the scientific world.For the past year, BCube, an EarthCube Building Block project, has been developing, testing and deploying a technology stack capable of data discovery at web-scale using the ultimate dataset: The Internet. This stack has 2 principal components, a web-scale crawling infrastructure and a semantic aggregator. The web-crawler is a modified version of Apache Nutch (the originator of Hadoop and other big data technologies) that has been improved and tailored for data and data service discovery. The second component is semantic aggregation, carried out by a python-based workflow that extracts valuable metadata and stores it in the form of triples through the use semantic technologies.While implementing the BCube stack we have run into several challenges such as a) scaling the project to cover big portions of the Internet at a reasonable cost, b) making sense of very diverse and non-homogeneous data, and lastly, c) extracting facts about these datasets using semantic technologies in order to make them usable for the geosciences community. Despite all these challenges we have proven that we can discover and characterize data that otherwise would have remained in the dark corners of the Internet. Having all this data indexed and 'triplelized' will enable scientists to access a trove of information relevant to their work in a more natural way. An important characteristic of the BCube stack is that all the code we have developed is open sourced and available to anyone who wants to experiment and collaborate with the project at: http://github.com/b-cube/
New Ethical Challenges within Environmental and Sustainability Education: A Response
ERIC Educational Resources Information Center
Todd, Sharon
2016-01-01
One of the major points to grow out of the four papers presented in this issue is how to think of education in relation to the various challenges facing the biosphere, facing the future of human and other than human life forms, and facing the sheer difficulties of planning what to do about them. The differences in the role of education, of course,…
Performance and accountability : challenges facing the Department of Transportation
DOT National Transportation Integrated Search
2001-02-14
For surface transportation safety, DOT continues to face challenges in improving the safety of highways and pipelines. While the Department of Transportation appears to be making progress on some initiatives to reduce the number of large truck crashe...
Toward a Social Psychophysics of Face Communication.
Jack, Rachael E; Schyns, Philippe G
2017-01-03
As a highly social species, humans are equipped with a powerful tool for social communication-the face. Although seemingly simple, the human face can elicit multiple social perceptions due to the rich variations of its movements, morphology, and complexion. Consequently, identifying precisely what face information elicits different social perceptions is a complex empirical challenge that has largely remained beyond the reach of traditional methods. In the past decade, the emerging field of social psychophysics has developed new methods to address this challenge, with the potential to transfer psychophysical laws of social perception to the digital economy via avatars and social robots. At this exciting juncture, it is timely to review these new methodological developments. In this article, we introduce and review the foundational methodological developments of social psychophysics, present work done in the past decade that has advanced understanding of the face as a tool for social communication, and discuss the major challenges that lie ahead.
Spin-on metal oxide materials for N7 and beyond patterning applications
NASA Astrophysics Data System (ADS)
Mannaert, G.; Altamirano-Sanchez, E.; Hopf, T.; Sebaai, F.; Lorant, C.; Petermann, C.; Hong, S.-E.; Mullen, S.; Wolfer, E.; Mckenzie, D.; Yao, H.; Rahman, D.; Cho, J.-Y.; Padmanaban, M.; Piumi, D.
2017-04-01
There is a growing interest in new spin on metal oxide hard mask materials for advanced patterning solutions both in BEOL and FEOL processing. Understanding how these materials respond to plasma conditions may create a competitive advantage. In this study patterning development was done for two challenging FEOL applications where the traditional Si based films were replaced by EMD spin on metal oxides, which acted as highly selective hard masks. The biggest advantage of metal oxide hard masks for advanced patterning lays in the process window improvement at lower or similar cost compared to other existing solutions.
Remaining challenges in childhood cancer and newer targeted therapeutics.
Smith, Malcolm A; Reaman, Gregory H
2015-02-01
Despite the enormously important and gratifying advances in cancer treatment outcomes for children with cancer, cancer remains the biggest cause of death from disease in children. Because the etiology and biology of cancers that occur in children differ dramatically from those that occur in adults, the immediate extrapolation of efficacy and safety of new cancer drugs to childhood cancer indications is not possible. We discuss factors that will play key roles in guiding pediatric oncologists as they select lines of research to pursue in their quest for more effective treatments for children with cancer. Published by Elsevier Inc.
Protected quantum computing: interleaving gate operations with dynamical decoupling sequences.
Zhang, Jingfu; Souza, Alexandre M; Brandao, Frederico Dias; Suter, Dieter
2014-02-07
Implementing precise operations on quantum systems is one of the biggest challenges for building quantum devices in a noisy environment. Dynamical decoupling attenuates the destructive effect of the environmental noise, but so far, it has been used primarily in the context of quantum memories. Here, we experimentally demonstrate a general scheme for combining dynamical decoupling with quantum logical gate operations using the example of an electron-spin qubit of a single nitrogen-vacancy center in diamond. We achieve process fidelities >98% for gate times that are 2 orders of magnitude longer than the unprotected dephasing time T2.
[Progress of research in relation to the impact of climate change on children's health status].
Gao, J H; Li, L P; Wang, J; Liu, X B; Wu, H X; Li, J; Li, J; Liu, Q Y
2017-06-10
Along with global warming, climate change has become one of the biggest public health challenges. The unique metabolism, behavior, physiology and development in children, will make them suffer more from the climate change. In the present review, we summarized the progress and situation of studies on the associations between climate change and children's health also trying to provide adaptation and mitigation strategies. The purpose of this study was to offer scientific evidence for prevention and control on the adverse effects as injuries, diseases and deaths among children that resulted from the changes of climate.
Protein crystal screening and characterization for serial femtosecond nanocrystallography
Darmanin, Connie; Strachan, Jamie; Adda, Christopher G.; Ve, Thomas; Kobe, Bostjan; Abbey, Brian
2016-01-01
The recent development of X-ray free electron lasers (XFELs) has spurred the development of serial femtosecond nanocrystallography (SFX) which, for the first time, is enabling structure retrieval from sub-micron protein crystals. Although there are already a growing number of structures published using SFX, the technology is still very new and presents a number of unique challenges as well as opportunities for structural biologists. One of the biggest barriers to the success of SFX experiments is the preparation and selection of suitable protein crystal samples. Here we outline a protocol for preparing and screening for suitable XFEL targets. PMID:27139248
Health information technology: a few years of magical thinking?
Diamond, Carol C; Shirky, Clay
2008-01-01
One of the biggest obstacles to expanding the use of information technology (IT) in health care may be the current narrow focus on how to stimulate its adoption. The challenge of thinking of IT as a tool to improve quality requires serious attention to transforming the U.S. health care system as a whole, rather than simply computerizing the current setup. Proponents of health IT must resist "magical thinking," such as the notion that technology will transform our broken system, absent integrated work on policy or incentives. The alternative route to transforming the system sets all of its sights on the destination.
Tesler, Laura E; Malone, Ruth E
2010-07-01
Contemporary health care reformers, like those who promoted the failed Clinton era plan, face opposition from multiple corporate interests. However, scant literature has examined how relationships between corporations and other stakeholders, such as think tanks and advocacy groups, shape health care reform debate. We show how the 2 biggest US tobacco companies, Philip Morris and RJ Reynolds, and their trade association coordinated in mobilizing ideologically diverse constituencies to help defeat the Clinton plan. Unwittingly perhaps, some reform supporters advanced the tobacco industry's public relations blitz, contributing to perceptions of public opposition to the plan. As the current reform debate unfolds, this case highlights the importance of funding transparency for interpreting the activities of think tanks, advocacy groups, and "grassroots" movements.
Studying the nonlinearity in Sonic IR NDE
NASA Astrophysics Data System (ADS)
Yu, Qiuye; Obeidat, Omar; Han, Xiaoyan
2017-02-01
Sonic IR Imaging combines pulsed ultrasound excitation and infrared imaging to detect defects in materials. The sound pulse causes rubbing due to non--unison motion between faces of defects, and infrared sensors image the temperature map over the target to identify defects. It works in various materials, including metal/metal alloy, ceramics, and composite materials. Its biggest advantage is that it's a fast, wide area NDE technique. It takes only a fraction of a second or a few seconds, depending on the thermal properties of the target, for one test over a few square feet. However, due to the nonlinearity in the coupling between the ultrasound transducer and the target, the repeatability has been an issue, which affects its application. In this paper, we present our study on this issue in Sonic IR.
Pose-Invariant Face Recognition via RGB-D Images.
Sang, Gaoli; Li, Jing; Zhao, Qijun
2016-01-01
Three-dimensional (3D) face models can intrinsically handle large pose face recognition problem. In this paper, we propose a novel pose-invariant face recognition method via RGB-D images. By employing depth, our method is able to handle self-occlusion and deformation, both of which are challenging problems in two-dimensional (2D) face recognition. Texture images in the gallery can be rendered to the same view as the probe via depth. Meanwhile, depth is also used for similarity measure via frontalization and symmetric filling. Finally, both texture and depth contribute to the final identity estimation. Experiments on Bosphorus, CurtinFaces, Eurecom, and Kiwi databases demonstrate that the additional depth information has improved the performance of face recognition with large pose variations and under even more challenging conditions.
ERIC Educational Resources Information Center
Fier, Sara M.; Brzezinski, Lynda G.
2010-01-01
The transition from high school to college is challenging for many students. In addition to the typical challenges faced by students starting college, students with previously diagnosed psychiatric disabilities have illness-related challenges to face as they transition to college. This article provides information on the current state of concerns…
ERIC Educational Resources Information Center
Dipeolu, Abiola O.; Storlie, Cassandra; Johnson, Carol
2015-01-01
The transition from college to work is a challenging time for students with autism spectrum disorder. College counselors who understand the challenges students face adjusting to the world of work can position themselves to be change agents for this population. This article illuminates the challenges facing these students to help close the…
ERIC Educational Resources Information Center
Yalcin-Celik, Ayse; Kadayifci, Hakki; Uner, Sinem; Turan-Oluk, Nurcan
2017-01-01
This study examines the challenges faced by pre-service chemistry teachers teaching in a laboratory and their proposed solutions to these challenges. The study was conducted in a 13-week-long methodology course. Written statements from participants and observations from researchers were used as data sources. From these data, it was found that the…
Investigation of the Challenges, Mentoring Needs, and Support for Business and Marketing Teachers
ERIC Educational Resources Information Center
Yohon, Teresa
2005-01-01
The purpose of this study was to determine the challenges that new business/marketing teachers face as well as the current support structures available to them and to determine experienced business/marketing teachers perceptions of the challenges faced by new teachers as well as the types of support that they were willing to provide to new…
Challenges Faced by a Faith-Based School in a Rural, Predominantly Secular Setting: Implications
ERIC Educational Resources Information Center
Evangelinou-Yiannakis, Angela
2016-01-01
A new, independent Catholic school in rural Australia has had to face significant challenges in relation to its distinct Catholic ethos and curriculum. The challenges have included resistance from parents of the School with regard to the weekly time allocation for Religious Education, the nature of the faith-based curriculum, and the way in which…
Koch, Tomas F; Leal, Valentina J; Ayala, Ricardo A
2016-01-01
The discussion of teaching and learning in nursing has been prolific. Whereas most of the debate tends to focus on core contents of nursing programmes, little has been discussed about the teaching in 'supporting subjects' with relevance to both nursing education and nursing practice. This article offers a perspective on sociology scholarship for applied professions by using the case of nursing programmes. Syllabus is a rich source of data, and in its representational capacity it becomes both a discursive construction and a vehicle of ideology. Accordingly, we present a Critical Discourse Analysis of syllabi of nursing schools in Chile as to identify core contents and ideologies, and implied challenges for nursing education. We argue that while the syllabus as a discourse discloses a significant cleavage, the biggest challenge is precisely to challenge the ideologies constructed by and embedded in the syllabi. Our reflection thus points to a better interdisciplinary dialogue as to enhance the actual contribution of sociology to nursing. Copyright © 2015 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Demir, I.; Krajewski, W. F.
2013-12-01
As geoscientists are confronted with increasingly massive datasets from environmental observations to simulations, one of the biggest challenges is having the right tools to gain scientific insight from the data and communicate the understanding to stakeholders. Recent developments in web technologies make it easy to manage, visualize and share large data sets with general public. Novel visualization techniques and dynamic user interfaces allow users to interact with data, and modify the parameters to create custom views of the data to gain insight from simulations and environmental observations. This requires developing new data models and intelligent knowledge discovery techniques to explore and extract information from complex computational simulations or large data repositories. Scientific visualization will be an increasingly important component to build comprehensive environmental information platforms. This presentation provides an overview of the trends and challenges in the field of scientific visualization, and demonstrates information visualization and communication tools developed within the light of these challenges.
OOSTT: a Resource for Analyzing the Organizational Structures of Trauma Centers and Trauma Systems
Utecht, Joseph; Judkins, John; Otte, J. Neil; Colvin, Terra; Rogers, Nicholas; Rose, Robert; Alvi, Maria; Hicks, Amanda; Ball, Jane; Bowman, Stephen M.; Maxson, Robert T.; Nabaweesi, Rosemary; Pradhan, Rohit; Sanddal, Nels D.; Tudoreanu, M. Eduard; Winchell, Robert J.; Brochhausen, Mathias
2017-01-01
Organizational structures of healthcare organizations has increasingly become a focus of medical research. In the CAFÉ project we aim to provide a web-service enabling ontology-driven comparison of the organizational characteristics of trauma centers and trauma systems. Trauma remains one of the biggest challenges to healthcare systems worldwide. Research has demonstrated that coordinated efforts like trauma systems and trauma centers are key components of addressing this challenge. Evaluation and comparison of these organizations is essential. However, this research challenge is frequently compounded by the lack of a shared terminology and the lack of effective information technology solutions for assessing and comparing these organizations. In this paper we present the Ontology of Organizational Structures of Trauma systems and Trauma centers (OOSTT) that provides the ontological foundation to CAFÉ's web-based questionnaire infrastructure. We present the usage of the ontology in relation to the questionnaire and provide the methods that were used to create the ontology. PMID:28217041
Challenges for nurses who work in community mental health centres in the West Bank, Palestine.
Marie, Mohammad; Hannigan, Ben; Jones, Aled
2017-01-01
Nurses in Palestine (occupied Palestinian territory) work in a significantly challenging environment. The mental health care system is underdeveloped and under-resourced. For example, the total number of nurses who work in community mental health centres in the West Bank is seventeen, clearly insufficient in a total population of approximately three million. This research explored daily challenges that Palestinian community mental health nurses (CMHNs) face within and outside their demanding workplaces. An interpretive qualitative design was chosen. Face-to-face interviews were completed with fifteen participants. Thirty-two hours of observations of the day-to-day working environment and workplace routines were conducted in two communities' mental health centres. Written documents relating to practical job-related policies were also collected from various workplaces. Thematic analysis was used across all data sources resulting in four main themes, which describe the challenges faced by CMHNs. These themes consist of the context of unrest, stigma, lack of resources, and organisational or mental health system challenges. The study concludes with a better understanding of challenges in nursing which draws on wider cultural contexts and resilience. The outcomes from this study can be used to decrease the challenges for health professionals and enhance the mental health care system in Palestine.
Yates, Kimberly K.; Turley, Carol; Hopkinson, Brian M.; Todgham, Anne E.; Cross, Jessica N.; Greening, Holly; Williamson, Phillip; Van Hooidonk, Ruben; Deheyn, Dimitri D.; Johnson, Zachary
2015-01-01
The global nature of ocean acidification (OA) transcends habitats, ecosystems, regions, and science disciplines. The scientific community recognizes that the biggest challenge in improving understanding of how changing OA conditions affect ecosystems, and associated consequences for human society, requires integration of experimental, observational, and modeling approaches from many disciplines over a wide range of temporal and spatial scales. Such transdisciplinary science is the next step in providing relevant, meaningful results and optimal guidance to policymakers and coastal managers. We discuss the challenges associated with integrating ocean acidification science across funding agencies, institutions, disciplines, topical areas, and regions, and the value of unifying science objectives and activities to deliver insights into local, regional, and global scale impacts. We identify guiding principles and strategies for developing transdisciplinary research in the ocean acidification science community.
Pretorius, Isak S.; Curtin, Christopher D.; Chambers, Paul J.
2012-01-01
The past three decades have seen a global wine glut. So far, well-intended but wasteful and expensive market-intervention has failed to drag the wine industry out of a chronic annual oversupply of roughly 15%. Can yeast research succeed where these approaches have failed by providing a means of improving wine quality, thereby making wine more appealing to consumers? To molecular biologists Saccharomyces cerevisiae is as intriguing as it is tractable. A simple unicellular eukaryote, it is an ideal model organism, enabling scientists to shed new light on some of the biggest scientific challenges such as the biology of cancer and aging. It is amenable to almost any modification that modern biology can throw at a cell, making it an ideal host for genetic manipulation, whether by the application of traditional or modern genetic techniques. To the winemaker, this yeast is integral to crafting wonderful, complex wines from simple, sugar-rich grape juice. Thus any improvements that we can make to wine, yeast fermentation performance or the sensory properties it imparts to wine will benefit winemakers and consumers. With this in mind, the application of frontier technologies, particularly the burgeoning fields of systems and synthetic biology, have much to offer in their pursuit of “novel” yeast strains to produce high quality wine. This paper discusses the nexus between yeast research and winemaking. It also addresses how winemakers and scientists face up to the challenges of consumer perceptions and opinions regarding the intervention of science and technology; the greater this intervention, the stronger the criticism that wine is no longer “natural.” How can wine researchers respond to the growing number of wine commentators and consumers who feel that scientific endeavors favor wine quantity over quality and “technical sophistication, fermentation reliability and product consistency” over “artisanal variation”? This paper seeks to present yeast research in a new light and a new context, and it raises important questions about the direction of yeast research, its contribution to science and the future of winemaking. PMID:22572786
NASA Astrophysics Data System (ADS)
Ryan, J. G.
2012-12-01
Bringing the use of cutting-edge research tools into student classroom experiences has long been a popular educational strategy in the geosciences and other STEM disciplines. The NSF CCLI and TUES programs have funded a large number of projects that placed research-grade instrumentation at educational institutions for instructional use and use in supporting undergraduate research activities. While student and faculty response to these activities has largely been positive, a range of challenges exist related to their educational effectiveness. Many of the obstacles these approaches have faced relate to "scaling up" of research mentoring experiences (e.g., providing training and time for use for an entire classroom of students, as opposed to one or two), and to time tradeoffs associated with providing technical training for effective instrument use versus course content coverage. The biggest challenge has often been simple logistics: a single instrument, housed in a different space, is difficult to integrate effectively into instructional activities. My CCLI-funded project sought primarily to knock down the logistical obstacles to research instrument use by taking advantage of remote instrument operation technologies, which allow the in-classroom use of networked analytical tools. Remote use of electron microprobe and SEM instruments of the Florida Center for Analytical Electron Microscopy (FCAEM) in Miami, FL was integrated into two geoscience courses at USF in Tampa, FL. Remote operation permitted the development of whole-class laboratory exercises to familiarize students with the tools, their function, and their capabilities; and it allowed students to collect high-quality chemical and image data on their own prepared samples in the classroom during laboratory periods. These activities improve student engagement in the course, appear to improve learning of key concepts in mineralogy and petrology, and have led to students pursuing independent research projects, as well as requesting additional Geology elective courses offering similar kinds of experiences. I have sustained these activities post-project via student lab fees to pay for in-class microprobe time.
Examining the Roles of the Facilitator in Online and Face-to-Face PD Contexts
ERIC Educational Resources Information Center
Park, Gina; Johnson, Heather; Vath, Richard; Kubitskey, Beth; Fishman, Barry
2013-01-01
Online teacher professional development has become an alternative to face-to-face professional development. Such a shift from face-to-face to online professional development, however, brings new challenges for professional development facilitators, whose roles are crucial in orchestrating teacher learning. This paper is motivated by the need to…
Milette, Katherine; Thombs, Brett D; Maiorino, Kristina; Nielson, Warren R; Körner, Annett; Peláez, Sandra
2018-05-09
The purpose of this study was to explore challenges faced by patients with systemic sclerosis, also called scleroderma, in coping with their disease and the strategies they used to face those challenges. Five focus groups were held with scleroderma patients (4 groups, n = 34) and health care professionals who have experience treating scleroderma (1 group, n = 8). Participants' discussions were recorded, transcribed and analyzed using thematic analysis. Participants reported challenges accessing information (e.g., knowledgeable specialists), dealing with negative emotions (e.g., stress due to misunderstandings with loved ones), and accessing resources (e.g., helpful products or devices). Strategies for overcoming challenges were also discussed (e.g., advocating for own needs). When faced with significant challenges while coping with scleroderma, patients develop strategies to manage better and improve their quality of life. To help them cope, patients would benefit from easier access to supportive interventions, including tailored scleroderma self-management programs. Although the challenges experienced by patients with scleroderma are unique, findings from this study might help better understand patients' perspectives regarding coping and disease management for other chronic diseases as well. Implications for Rehabilitation People living with rare diseases, including the rare autoimmune disease scleroderma, face unique challenges and often do not have access to disease-specific educational or other support resources. People with scleroderma report that they face challenges in accessing information, including knowledgeable healthcare providers; managing difficult social interactions and negative emotions; and accessing resources. Strategies employed by scleroderma patients to overcome these challenges include seeking connections to other people with scleroderma or scleroderma patient organizations, actively seeking out local resources, and learning to communicate and advocate more effectively. Rehabilitation professionals can support people with scleroderma by providing them with information on connecting with scleroderma patient organizations or by facilitating local patient support networks.
Peláez, Sandra; Hendricks, Kristin N; Merry, Lisa A; Gagnon, Anita J
2017-01-25
People who leave their country of origin, or the country of habitual residence, to establish themselves permanently in another country are usually referred to as migrants. Over half of all births in Montreal, Canada are to migrant women. To understand healthcare professionals' attitudes towards migrants that could influence their delivery of care, our objective was to explore their perspectives of challenges newly-arrived migrant women from non-Western countries face when needing maternity care. In this qualitative multiple case study, we conducted face-to-face interviews with 63 health care professionals from four teaching hospitals in Montreal, known for providing maternity care to a high volume of migrant women. Interviews were transcribed and thematically analysed. Physicians, nurses, social workers, and therapists participated; 90% were female; and 17% were themselves migrants from non-Western countries. According to participants, newly-arrived migrant women face challenges at two levels: (a) direct care (e.g., understanding Canadian health care professionals' expectations, communicating effectively with health care professionals), and (b) organizational (e.g., access to appropriate health care). Challenges women face are strongly influenced by the migrant woman's background as well as social position (e.g., general education, health literacy, socio-cultural integration) and by how health care professionals balance women's needs with perceived requirement to adhere to standard procedures and regulations. Health care professionals across institutions agreed that maternity care-related challenges faced by newly-arrived migrant women often are complex in that they are simultaneously driven by conflicting values: those based on migrant women's sociocultural backgrounds versus those related to the implementation of Canadian guidelines for maternity care in which consideration of migrant women's particular needs are not priority.
ERIC Educational Resources Information Center
Armstrong, Alan
2014-01-01
This paper brings together the main strengths and challenges currently facing Scottish education and outlines approaches to the ways forward. Knowledge about how to improve education systems has grown rapidly over the last two decades. One key challenge facing Scotland, and no doubt many other countries, is in ensuring a smooth "learner…
Threat Control through Arms Control. Report to Congress 1994
1994-07-13
reduction, chemical weapons’ elimination, or any of the other growing arms control and nonproliferation challenges America faces, ACDA is an essential...nuclear missile reduction, chemical weapons elimination, or any of. the other growing arms control and nonproliferation challenges America faces... challenging . Nonprolif eration agreements are our first line of defense against the creation of a far more unstable and hazardous world than we have ever
ERIC Educational Resources Information Center
Dyrli, Kurt O.
2008-01-01
This article reports on the challenge that parents, teachers, and district administrators face in continuing to provide essential school supplies to their students despite budget cuts. At the Verona Area (Wisconsin) School District, administrators, teachers, and parents have recently faced this common challenge. Increasingly dependent on funding…
Challenges and Concerns Faced by Doctoral Candidates Seeking Academic Positions.
ERIC Educational Resources Information Center
Porter, Dion; Donnell, Chandra; Buck, Tina; Edwards, Yolanda
A panel discussion offered suggestions and recommendations for faculty and institutions of rehabilitation counseling education on more effective recruitment methods. Strategies were also considered for potential faculty members. Candidates seeking academic positions in rehabilitation counseling education face many challenges. Location of program;…
Resnik, Linda J; Allen, Susan M
2007-01-01
This pilot study used the framework of the World Health Organization's International Classification of Functioning, Disability and Health (ICF) to understand the challenges faced by Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) veterans as they reintegrate into the community. We conducted semistructured interviews with 14 injured veterans, 12 caregivers, and 14 clinicians. We used ICF taxonomy to code data and identify issues. We identified challenges in the following ICF domains: learning and applying knowledge; general tasks and demands; communication; mobility; self-care; domestic life; interpersonal interactions, major life areas; and community, social, and civic life. We found many similarities between the challenges faced by veterans with and without polytraumatic injuries, although veterans with polytraumatic injuries faced challenges of greater magnitude. Identifying community reintegration challenges early and promoting reintegration are important mandates for the Department of Veterans Affairs. The findings of this study are useful in understanding the needs of OEF/OIF veterans.
Magalhães-Sant'Ana, M.; More, S. J.; Morton, D. B.; Hanlon, A.
2016-01-01
Ethics is key to the integrity of the veterinary profession. Despite its importance, there is a lack of applied research on the range of ethical challenges faced by veterinarians. A three round Policy Delphi with vignette methodology was used to record the diversity of views on ethical challenges faced by veterinary professionals in Ireland. Forty experts, comprising veterinary practitioners, inspectors and nurses, accepted to participate. In round 1, twenty vignettes describing a variety of ethically challenging veterinary scenarios were ranked in terms of ethical acceptability, reputational risk and perceived standards of practice. Round 2 aimed at characterising challenges where future policy development or professional guidance was deemed to be needed. In round 3, possible solutions to key challenges were explored. Results suggest that current rules and regulations are insufficient to ensure best veterinary practices and that a collective approach is needed to harness workable solutions for the identified ethical challenges. Challenges pertaining mostly to the food chain seem to require enforcement measures whereas softer measures that promote professional discretion were preferred to address challenges dealing with veterinary clinical services. These findings can support veterinary representative bodies, advisory committees and regulatory authorities in their decision making, policy and regulation. PMID:27613779
Examining the Challenging Hindrances facing in the Construction Projects: South India’s Perspective
NASA Astrophysics Data System (ADS)
Subramanyam, K.; Haridharan, M. K.
2017-07-01
Developing countries like India require a huge infrastructure to facilitate needs of the people. Construction industry provides several opportunities to the individuals. Construction manager work is to supervise and organize the construction activities in construction projects. Now a day construction manager facing challenges. This paper aimed to study the challenges facing by the construction manager in the perception of construction professionals. 39 variables were taken from the literature review which found to be severe impact on construction managers’ performance. Construction manager, project manager and site engineers are the respondents for this survey. Using SPSS, regression analysis was done and recognized significant challenges. These challenges were classified into 5 domains. In management challenges, resource availability and allocation, risks and uncertainties existing in the project onsite, top management support and cost constraints are the most significant variables. In skills requirement of a construction manager challenges, technical skills required to learn and adapt new technology in the project, decision making and planning according to the situation in site are the most significant variables. In performance challenges, implementation of tasks according to the plan is the important variable whereas in onsite challenges, manage project risks, develop project policies and procedures are the most important.
Magalhães-Sant'Ana, M; More, S J; Morton, D B; Hanlon, A
2016-10-29
Ethics is key to the integrity of the veterinary profession. Despite its importance, there is a lack of applied research on the range of ethical challenges faced by veterinarians. A three round Policy Delphi with vignette methodology was used to record the diversity of views on ethical challenges faced by veterinary professionals in Ireland. Forty experts, comprising veterinary practitioners, inspectors and nurses, accepted to participate. In round 1, twenty vignettes describing a variety of ethically challenging veterinary scenarios were ranked in terms of ethical acceptability, reputational risk and perceived standards of practice. Round 2 aimed at characterising challenges where future policy development or professional guidance was deemed to be needed. In round 3, possible solutions to key challenges were explored. Results suggest that current rules and regulations are insufficient to ensure best veterinary practices and that a collective approach is needed to harness workable solutions for the identified ethical challenges. Challenges pertaining mostly to the food chain seem to require enforcement measures whereas softer measures that promote professional discretion were preferred to address challenges dealing with veterinary clinical services. These findings can support veterinary representative bodies, advisory committees and regulatory authorities in their decision making, policy and regulation. British Veterinary Association.
Challenges facing developers of CAD/CAM models that seek to predict human working postures
NASA Astrophysics Data System (ADS)
Wiker, Steven F.
2005-11-01
This paper outlines the need for development of human posture prediction models for Computer Aided Design (CAD) and Computer Aided Manufacturing (CAM) design applications in product, facility and work design. Challenges facing developers of posture prediction algorithms are presented and discussed.
Challenges Facing Early Childhood Programs Worldwide
ERIC Educational Resources Information Center
Neugebauer, Roger
2008-01-01
In this article, the author presents the challenges faced by early childhood education in 29 countries, according to the World Forum National Representatives and Global Leaders for Young Children. The countries represented in these responses include: Azerbaijan, Bangladesh, Bolivia, Brazil, Canada, Denmark, Egypt, Fiji, India, Iran, Iraq, Japan,…
Exploring Biotechnology Using Case-Based Multimedia
ERIC Educational Resources Information Center
Bergland, Mark; Lundeberg, Mary; Klyczek, Karen; Sweet, Jennifer; Emmons, Jean; Martin, Christine; Marsh, Katherine; Werner, Joy; Jarvis-Uetz, Michelle
2006-01-01
Today, teachers face more challenges than ever, and biology teachers face a special challenge. As technology continues to expand, biology teachers have a responsibility to keep students informed of technological and scientific advances. Biology teachers must also address ethical issues associated with these advances. In this paper, the authors…
ERIC Educational Resources Information Center
Alidmat, Ali Odeh Hammoud; Ayassrah, Mohamed Ayed
2017-01-01
Teaching English for Special Purposes (ESP) in a context where English is taught as a Foreign Language (EFL) is no easy task. There is in fact extensive research reporting on challenges facing both teacher and student in the Foreign Language classroom where language skills must be learnt outside their usual context. Even more challenging is…
Kho, Boon Phiaw; Hassali, Mohamed Azmi; Lim, Ching Jou; Saleem, Fahad
2018-03-15
The aims of this research were to determine extra-organisational challenges (e.g. market competition, governing policies) faced by community pharmacies in Sarawak, the coping strategies employed to deal with these challenges and explore potential legislative changes that can attenuate the intensity of these challenges. Survey questionnaires (n = 184) were posted to all eligible community pharmacies in Sarawak, Malaysia. The questionnaire included sections on participants' demographic data, extra-organisational challenges faced, coping strategies employed and proposals to improve community pharmacy legislations. Items were constructed based on the findings of a prior qualitative research supplemented with relevant literature about these issues. High levels of homogeneity in responses were recorded on various extra-organisational challenges faced, particularly those economy-oriented. Strategic changes to counter these challenges were focused on pricing and product stocked, rather than services provision. Highly rated strategies included increasing discounts for customers (n = 54; 68%) and finding cheaper suppliers (n = 70; 88%). Legislative changes proposed that might increase their share of the pharmaceutical market were strongly supported by respondents, particularly about making it compulsory for general practitioners to provide patients the option to have their medicines dispensed in community pharmacies (n = 72; 90%). Current legislative conditions and Malaysian consumer mindset may have constrained the strategic choices of community pharmacies to deal with the strong extra-organisational challenges. A long-term multipronged approach to address these issues and increased involvement of community pharmacists themselves in this agenda are required to influence practice change. © 2018 Royal Pharmaceutical Society.
The "Biggest Loser" Expounds on the Benefits of Losing Pounds
... because we are just regular people." Biggest Loser Fans Chime In "The more we learn and have ... where they were signing autographs and inspiring their fans to slim down, too. "Remember," they urged, "nothing ...
Multi-Institution Research Centers: Planning and Management Challenges
ERIC Educational Resources Information Center
Spooner, Catherine; Lavey, Lisa; Mukuka, Chilandu; Eames-Brown, Rosslyn
2016-01-01
Funding multi-institution centers of research excellence (CREs) has become a common means of supporting collaborative partnerships to address specific research topics. However, there is little guidance for those planning or managing a multi-institution CRE, which faces specific challenges not faced by single-institution research centers. We…
ERIC Educational Resources Information Center
Jackson, Liz; Han, Ana Yoon Jin
2016-01-01
Internationalisation in education facilitates student and teacher mobility. Though Hong Kong has embraced internationalisation in education, international university students can face challenges related to cultural difference. In teacher education, these challenges can be amplified, as student-teachers face expectations to teach schoolchildren…
Anger and Globalization among Young People in India
ERIC Educational Resources Information Center
Suchday, Sonia
2015-01-01
This article addresses the challenges faced by youth in developing countries. Using India as an example of a fast-globalizing country, this article highlights the experience and challenges faced by adolescents and emerging adults as they search for their interpersonal and professional identities. The difficulties of defining identity in the…
The Challenges Facing Catholic Education in France Today
ERIC Educational Resources Information Center
Moog, François
2016-01-01
The effects of secularisation on society demand a rethinking of the identity and mission of Catholic schools in France. In 2013, the French bishops published a new directory which offers new approaches, described here, based on the three challenges facing Catholic education in France: linking social responsibility and evangelisation, setting up…
An Inventory and Use Analysis of Information Systems on Small Farms in Pennsylvania
ERIC Educational Resources Information Center
Adams, Jean S.
2007-01-01
Across the United States, today's farm operators face continuing challenges from global competition, increasing production costs, changing technology, increased regulations, scarce resources, and lower profit margins. To face these challenges, farm operators need to gather and utilize information allowing them to make informed decisions. Several…
Anatomy Education Faces Challenges in Pakistan
ERIC Educational Resources Information Center
Memon, Ismail K.
2009-01-01
Anatomy education in Pakistan is facing many of the same challenges as in other parts of the world. Roughly, a decade ago, all medical and dental colleges in Pakistan emphasized anatomy as a core basic discipline within a traditional medical science curriculum. Now institutions are adopting problem based learning (PBL) teaching philosophies, and…
ERIC Educational Resources Information Center
Zilliox, Joseph T.; Lowery, Shannon G.
1997-01-01
Describes an extended investigation of polygons and polyhedra which was conducted in response to a challenge posed in Focus, a newsletter from the Mathematical Association of America (MAA). Students were challenged to construct a polyhedron with faces that measure more than 13 inches to a side. Outlines the process, including the questions posed…
Women Superintendents in Illinois: Gender Barriers and Challenges
ERIC Educational Resources Information Center
VanTuyle, Vicki; Watkins, Sandra G.
2009-01-01
Women face unique challenges as superintendents. This study determined barriers women face as superintendents and elicited reasons why these women would consider leaving the superintendent's position. Thirty-nine PreK-12 women superintendents in Illinois participated in a web-based survey in January 2008. Survey items included information…
Plural Societies and the Possibility of Shared Citizenship
ERIC Educational Resources Information Center
Merry, Michael S.
2012-01-01
As civilization pushes headlong into the twenty-first century, increasingly stringent demands for citizenship issue forth from governments around the world faced with a formidable assortment of challenges. Faced with these challenges, states are exploring ways to elicit civic attachments from their heterogeneous populations, but doing so is…
Challenges Facing Principals in the First Year at Their Schools
ERIC Educational Resources Information Center
Bayar, Adem
2016-01-01
The aim of this study is to identify key challenges of practice that principals face. In line with this purpose, the researcher has employed a qualitative research methodology, interviewing principals working in Amasya district, over and above doing document analysis to collect detailed information concerning leadership and administration…
Perspectives on Urban Geography in Advanced Placement® Human Geography
ERIC Educational Resources Information Center
Benton-Short, Lisa; Monk, Liliana
2016-01-01
"Perspectives on Urban Geography" constitutes a major part of the AP Human Geography course outline. In this article, urban core revitalization and rising suburban poverty are considered as two challenges facing cities in developed countries; and industrialization and the growth of megacities as two challenges facing cities in developing…
Homeless Children: Meeting the Educational Challenges. ERIC Digest.
ERIC Educational Resources Information Center
Goins, Brad; Cesarone, Bernard
Difficulties faced by homeless children include depression, low self-esteem, lack of sleep and nutrition, and feelings of shame and embarrassment. Challenges faced by schools in providing education to homeless children include: (1) keeping children in one school despite frequent family moves; (2) ensuring that children's health records are…
The Big Picture and Specifics of College General Education
ERIC Educational Resources Information Center
Gan, Yang
2018-01-01
In recent years, general education has developed considerably in Chinese universities, but it still faces many challenges and problems. Among the various negative factors, four problems may be the greatest challenges currently faced by Chinese university general education and ordinary undergraduate education: (1) In the era of massified higher…
Autism and Reading: Teaching a Sudanese Refugee Boy
ERIC Educational Resources Information Center
Walker-Dalhouse, Doris; Dalhouse, A. Derick
2015-01-01
Refugee families in the United States face numerous challenges in becoming acculturated. School-age children of refugees face the additional challenges of acquiring academic language and meeting school expectations for behavior and social interactions while attempting to navigate the school curriculum. This case study examines the school and home…
NASA Astrophysics Data System (ADS)
Callis-Duehl, Kristine; Idsardi, Robert; Humphrey, Eve A.; Gougis, Rebekka Darner
2018-02-01
We explored the scientific argumentation that occurs among university biology students during an argumentation task implemented in two environments: face-to-face in a classroom and online in an asynchronous discussion. We observed 10 student groups, each composed of three students. Our analysis focused on how students respond to their peers' unscientific arguments, which we define as assertions, hypotheses, propositions, or explanations that are inaccurate or incomplete from a scientific perspective. Unscientific arguments provide opportunities for productive dissent, scientific argumentation, and conceptual development of scientifically desirable conceptions. We found that students did not respond to the majority of unscientific arguments in both environments. Challenges to unscientific arguments were expressed as a question or through explanation, although the latter was more common online than face-to-face. Students demonstrated significantly more epistemic distancing in the face-to-face environment than the online environment. We discuss the differences in discourse observed in both environments and teaching implications. We also provide direction for future research seeking to address the challenges of engaging students in productive scientific argumentation in both face-to-face and online environments.
NASA Astrophysics Data System (ADS)
Stock, F.; Antoni, F.; Le Normand, F.; Muller, D.; Abdesselam, M.; Boubiche, N.; Komissarov, I.
2017-09-01
For the future, one of the biggest challenge faced to the technologies of flat panel display and various optoelectronic and photovoltaic devices is to find an alternative to the use of transparent conducting oxides like ITO. In this new approach, the objective is to grow high conductive thin-layer graphene (TLG) on the top of diamond-like carbon (DLC) layers presenting high performance. DLC prepared by pulsed laser deposition (PLD) have attracted special interest due to a unique combination of their properties, close to those of monocrystalline diamond, like its transparency, hardness and chemical inertia, very low roughness, hydrogen-free and thus high thermal stability up to 1000 K. In our future work, we plane to explore the synthesis of conductive TLG on top of insulating DLC thin films. The feasibility and obtained performances of the multi-layered structure will be explored in great details in the short future to develop an alternative to ITO with comparable performance (conductivity of transparency). To select the best DLC candidate for this purpose, we focus this work on the physicochemical properties of the DLC thin films deposited by PLD from a pure graphite target at two wavelengths (193 and 248 nm) at various laser fluences. A surface graphenization process, as well as the required efficiency of the complete structure (TLG/DLC) will clearly be related to the DLC properties, especially to the initial sp3/sp2 hybridization ratio. Thus, an exhaustive description of the physicochemical properties of the DLC layers is a fundamental step in the research of comparable performance to ITO.
Elective Cesarean Section: It’s Impact on Neonatal Respiratory Outcome
Ramachandrappa, Ashwin; Jain, Lucky
2008-01-01
The transition from a fluid filled lung to one filled with air in a very short period of time is one of the biggest challenges a newborn faces after birth. Respiratory morbidity as a result of failure to clear fetal lung fluid is not uncommon, and can be particularly problematic in some infants delivered by elective cesarean section (ECS) without being exposed to labor. The increasing rates of cesarean deliveries in the United States and worldwide, have the potential for a significant impact on public health and health care costs due to the morbidity associated with this subgroup. Whereas the occurrence of birth asphyxia, trauma, and meconium aspiration is reduced by elective cesarean delivery, the risk of respiratory distress secondary to transient tachypnea of the newborn, surfactant deficiency, and pulmonary hypertension is increased. It is clear that physiologic events in the last few weeks of pregnancy coupled with the onset of spontaneous labor are accompanied by changes in the hormonal milieu of the fetus and its mother, resulting in preparation of the fetus for neonatal transition. Rapid clearance of fetal lung fluid is a key part of these changes, and is mediated in large part by transepithelial sodium reabsorption through amiloride-sensitive sodium channels in the alveolar epithelial cells, with only a limited contribution from mechanical factors and Starling forces. In this chapter we discuss the respiratory morbidity associated with ECS, the physiologic mechanisms underlying fetal lung fluid absorption and potential strategies for facilitating neonatal transition when infants are delivered by ECS before the onset of spontaneous labor. PMID:18456075
Mi Gauss es su Gauss: Lessons from Cross-Calibrating 40 years of Full Disk Magnetograms
NASA Astrophysics Data System (ADS)
Werginz, Zachary; Munoz-Jaramillo, Andres; Martens, Petrus C.; Harvey, J. W.
2017-08-01
Full-disk line-of-sight magnetograms from the Kitt Peak Vacuum Telescope (KPVT) are a highly valuable, but underutilized, source of data for understanding long-term solar variability. Here we present the results of a project for obtaining a cross-callibrated series of magnetograms spanning 40 years including KPVT (512 and SPMG), SOHO/MDI and SDO/HMI magnetographs. The biggest challenge we face is empirically identifying a calibration factor and estimate of uncertainty between instruments with little temporal overlap.Here we propose a method that fragments magnetograms into spherical quadrangles bounded by latitudes and longitudes and calculates various information such as total area, mean flux density, and distance from disk center. Our main assumption is that the Sun does not change significantly over daily time periods.First a magnetogram to be calibrated is differentially rotated to match a reference magnetogram in time. Then the smaller magnetogram is interpolated into the larger one to account for sub-pixel heliographic coordinates. We then produce equally spaced bands of latitude and longitude determined from a fragmentation parameter. These are used to map out regions on each magnetogram that are expected to relay the same information. Our efforts to cross-calibrate lead to results that vary with fragmentation parameters, the difference in time of selected magnetograms, and distance from disk center.Given that this cross-callibrated series will be made publically available, we are looking for constructive criticism, suggestions, and feedback. Please join us in making these data as good as they can be.
Research and development in pilot plant production of granular NPK fertilizer
NASA Astrophysics Data System (ADS)
Failaka, Muhamad Fariz; Firdausi, Nadia Zahrotul; Chairunnisa, Altway, Ali
2017-05-01
PT Pupuk Kaltim (Pupuk Kaltim) as one of the biggest fertilizer manufacturer in Indonesia, always striving to improve the product quality and achieve the optimal performance while facing the challenges of global competition NPK (Nitrogen, Phosphorus, Potassium) market. In order to continuously improve operations and processes of two units NPK compound plant, Pupuk Kaltim has successfully initiated a new facility which is referred to as a NPK pilot-scale research facility with design capacity of 30 kg/hr. This mini-plant is used to assist in the scale up of new innovations from laboratory research to better understand the effect of using new raw materials and experiment with process changes to improve quality and efficiency. The pilot installation is composed of the following main parts: mixer, screw feeder, granulator, dryer and cooler. The granulator is the equipment where NPK granules is formed by spraying appropriate steam and water onto raw materials in a rotating drum. The rotary dryer and cooler are intended for the drying process where temperature reduction and the final moisture are obtained. As a part of innovations project since 2014, the pilot plant has conducted many of experiments such as trials using Ammonium Sulfate (ZA) as a new raw material, alternative raw materials of Diammonium Phosphate (DAP), Potassium Chloride (KCl) and clay, and using a novel material of fly ash. In addition, the process engineering staff also conduct the trials of raw materials ratio so that an ideal formulation with lower cost can be obtained especially when it is applied in the existing full-scale plant.
How I learned to let my workers lead.
Stayer, R
1990-01-01
In 1980, Ralph Stayer owned a successful, growing sausage company that had him badly worried. Commitment was poor, motivation was lousy, the gap between performance and potential was enormous. Over the next five years, Stayer turned the company upside down, but only by turning himself upside down first. For years he had insisted on his own control, made all decisions, delegated nothing. But when he tried to picture what the company would have to look like to sell the most expensive sausage and still enjoy the biggest market share, he saw an organization whose employees took responsibility for their own work. After several false starts, he finally began in earnest by making himself give up much of his own authority. Stayer turned quality control over to the workers on the production line. Workers also began answering letters of complaint from customers. Rejects went from 5% to 0.5%. Employees thrived on their new responsibility and asked for more. Gradually, people on the shop floor took over personnel functions as well, followed by scheduling, budgeting, and capital improvements. Managers came to function more as coaches than as bosses. Stayer--a little to his own dismay--began to find himself superfluous. In mid-1985, the company faced a watershed decision--whether or not to accept a massive new order that would make huge demands on every employee and strain the company's capacities. Stayer asked the employees to make the decision. They accepted the challenge, and productivity, profits, and quality all rose dramatically. By the late 1980s, Stayer had reached his goal of working himself out of a job.
NASA Astrophysics Data System (ADS)
Berchoux, Tristan; Hutton, Craig; Watmough, Gary; Amoako Johnson, Fiifi; Atkinson, Peter
2017-04-01
With population increase and the urbanisation of rural areas, land scarcity is one of the biggest challenges now faced by communities in agrarian societies. At the household level, loss of land can be due to physical processes such as erosion, to social constraints such as inheritance, or to financial constraints such as loan reimbursement or the need of cash. For rural households, whose livelihoods are mainly based on agriculture, a decrease in the area of land cultivated can have significant consequences on their livelihood strategies, thus on their livelihood outcomes. However, it is still unclear how changes in cultivated area and agricultural productivity influence households' livelihood systems, including community capitals and households' livelihood strategies. This study aims to answer this gap by combining together earth observation from space, national census and participatory qualitative data into a community-wise analysis of the relationships between land cover dynamics, variability in agricultural production and livelihood activities. Its overarching aim is to investigate how land cover dynamics relates to changes in livelihood strategies and livelihood capitals. The study demonstrates that a change in land cover influences livelihood activities differently depending on the community capitals that households have access to. One significant aspect of integrating land dynamics with livelihood activities is its capacity to provide insights on the relationships between climate, agriculture, livelihood dynamics and rural development. More broadly, it gives policymakers new methods to characterise livelihood dynamics, thus to monitor some of the key Sustainable Development Goals: food security (SDG2), employment dynamics (SDG8), inequalities (SDG10) and sustainability of communities (SDG11).
Emerging roles for biomedical librarians: a survey of current practice, challenges, and changes
Crum, Janet A.; Cooper, I. Diane
2013-01-01
Objective: This study is intended to (1) identify emerging roles for biomedical librarians and determine how common these roles are in a variety of library settings, (2) identify barriers to taking on new roles, and (3) determine how librarians are developing the capacity to take on new roles. Methods: A survey was conducted of librarians in biomedical settings. Results: Most biomedical librarians are taking on new roles. The most common roles selected by survey respondents include analysis and enhancement of user experiences, support for social media, support for systematic reviews, clinical informationist, help for faculty or staff with authorship issues, and implementation of researcher profiling and collaboration tools. Respondents in academic settings are more likely to report new roles than hospital librarians are, but some new roles are common in both settings. Respondents use a variety of methods to free up time for new roles, but predominant methods vary between directors and librarians and between academic and hospital respondents. Lack of time is the biggest barrier that librarians face when trying to adopt new roles. New roles are associated with increased collaboration with individuals and/or groups outside the library. Conclusion and Implications: This survey documents the widespread incorporation of new roles in biomedical libraries in the United States, as well as the barriers to adopting these roles and the means by which librarians are making time for them. The results of the survey can be used to inform strategic planning, succession planning, library education, and career development for biomedical librarians. PMID:24163599
Localization system for use in GPS denied environments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Trueblood, J. J.
The military uses to autonomous platforms to complete missions to provide standoff for the warfighters. However autonomous platforms rely on GPS to provide their global position. In many missions spaces the autonomous platforms may encounter GPS denied environments which limits where the platform operates and requires the warfighters to takes its place. GPS denied environments can occur due to tall building, trees, canyon wall blocking the GPS satellite signals or a lack of coverage. An Inertial Navigation System (INS) uses sensors to detect the vehicle movement and direction its traveling to calculate the vehicle. One of biggest challenges with anmore » INS system is the accuracy and accumulation of errors over time of the sensors. If these challenges can be overcome the INS would provide accurate positioning information to the autonomous vehicle in GPS denied environments and allow them to provide the desired standoff for the warfighters.« less
Tuberculosis and mental health in the Asia-Pacific.
Mason, Paul H; Sweetland, Annika C; Fox, Greg J; Halovic, Shaun; Nguyen, Thu Anh; Marks, Guy B
2016-12-01
This opinion piece encourages mental health researchers and clinicians to engage with mental health issues among tuberculosis patients in the Asia-Pacific region in a culturally appropriate and ethical manner. The diversity of cultural contexts and the high burden of tuberculosis throughout the Asia-Pacific presents significant challenges. Research into tuberculosis and mental illness in this region is an opportunity to develop more nuanced models of mental illness and treatment, while simultaneously contributing meaningfully to regional tuberculosis care and prevention. We overview key issues in tuberculosis and mental illness co-morbidity, highlight ethical concerns and advocate for a regional approach to tuberculosis and mental health that is consistent with the transnational challenges presented by this airborne infectious disease. Integrating tuberculosis and mental health services will go a long way to addressing the needs of vulnerable populations and stopping the transmission of one of the world's biggest infectious killers. © The Royal Australian and New Zealand College of Psychiatrists 2016.
Dispenzieri, Angela; Buadi, Francis; Kumar, Shaji K; Reeder, Craig B; Sher, Tamur; Lacy, Martha Q; Kyle, Robert A; Mikhael, Joseph R; Roy, Vivek; Leung, Nelson; Grogan, Martha; Kapoor, Prashant; Lust, John A; Dingli, David; Go, Ronald S; Hwa, Yi Lisa; Hayman, Suzanne R; Fonseca, Rafael; Ailawadhi, Sikander; Bergsagel, P Leif; Chanan-Khan, Ascher; Rajkumar, S Vincent; Russell, Stephen J; Stewart, Keith; Zeldenrust, Steven R; Gertz, Morie A
2015-08-01
Immunoglobulin light chain amyloidosis (AL amyloidosis) has an incidence of approximately 1 case per 100,000 person-years in Western countries. The rarity of the condition not only poses a challenge for making a prompt diagnosis but also makes evidenced decision making about treatment even more challenging. Physicians caring for patients with AL amyloidosis have been borrowing and customizing the therapies used for patients with multiple myeloma with varying degrees of success. One of the biggest failings in the science of the treatment of AL amyloidosis is the paucity of prospective trials, especially phase 3 trials. Herein, we present an extensive review of the literature with an aim of making recommendations in the context of the best evidence and expert opinion. Copyright © 2015 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
Isolation and Flow Cytometry Analysis of Innate Lymphoid Cells from the Intestinal Lamina Propria.
Gronke, Konrad; Kofoed-Nielsen, Michael; Diefenbach, Andreas
2017-01-01
The intestinal mucosa constitutes the biggest surface area of the body. It is constantly challenged by bacteria, commensal and pathogenic, protozoa, and food-derived irritants. In order to maintain homeostasis, a complex network of signaling circuits has evolved that includes contributions of immune cells. In recent years a subset of lymphocytes, which belong to the innate immune system, has caught particular attention. These so-called innate lymphoid cells (ILC) reside within the lamina propria of the small and large intestines and rapidly respond to environmental challenges. They provide immunity to various types of infections but may also contribute to organ homeostasis as they produce factors acting on epithelial cells thereby enhancing barrier integrity. Here, we describe how these cells can be isolated from their environment and provide an in-depth protocol how to visualize the various ILC subsets by flow cytometry.
A PIECE OF THE SPACE SHUTTLE CHALLENGER WASHED ASHORE AT COCOA BEACH
NASA Technical Reports Server (NTRS)
1996-01-01
A Cocoa Beach front-end loader holds a large piece of debris from the Space Shuttle orbiter Challenger after it washed ashore in Cocoa Beach near the Coconuts on the Beach restaurant and bar. The piece, about 15 feet by 6 feet, is believed to be part of an elevon or rudder. It is one of the biggest pieces to wash ashore to date. A smaller piece was found several blocks south. NASA recovered thousands of pounds of debris from the Atlantic Ocean after the Jan. 28, 1986 accident which destroyed the Shuttle and claimed the lives of the seven crew members; about 50 percent of the orbiter remained in the ocean after search operations were suspended. Those remains are stored at Cape Canaveral Air Station, mostly in two Minutemen silos. The two newly recovered pieces will be brought by flatbed truck to KSC's Security Patrol Headquarters on Contractor Road for examination and temporary storage.
How Science Works - Evaluating Evidence in Biology and Medicine
NASA Astrophysics Data System (ADS)
Jenkins, Stephen H.
2004-04-01
One week, red wine is good for the heart. The next week, new reports say it's bad for the health. So which is true? Anyone who's ever read science news with fascination, or who's ever been confounded by conflicting stories will appreciate this book. Taking a look at some true to life contemporary news stories, the author assesses recent studies on topics ranging from vitamin C and caffeine to pollution and cancer. With straight talk and a passion for the whole project of science, he demysifies the cult of the expert and sheds light on the nitty-gritty details of scientific processes. Any scientist loves a challenge, but the biggest challenge of all, observes Jenkins, is shared by scientists and nonscientitsts alike: how to make practical decisions in light of ambiguous evidence. Promising no simple answers, this book does offer excellent food for thought for people pondering that next glass of wine.
Millennium Development Goals 4 and 5: progress and challenges.
Bryce, Jennifer; Black, Robert E; Victora, Cesar G
2013-10-16
The Millennium Development Goals have galvanized efforts to improve child survival (MDG-4) and maternal health (MDG-5). There has been important progress on both MDGs at global level, although it now appears that few countries will reach them by the target date of 2015. There are known and efficacious interventions to address most of the major causes of these deaths, but important gaps remain. The biggest challenge is to ensure that all women and children have access to life-saving interventions. Current levels of intervention coverage are too low, representing missed opportunities. Providing services at the community level is an important emerging priority, but preventing maternal and neonatal deaths also requires access to health facilities. Readers of the Medicine for Global Health collection in BMC Medicine are urged to make maternal and child health one of their key concerns, even if they work on other topics.
Tesler, Laura E.
2010-01-01
Contemporary health care reformers, like those who promoted the failed Clinton era plan, face opposition from multiple corporate interests. However, scant literature has examined how relationships between corporations and other stakeholders, such as think tanks and advocacy groups, shape health care reform debate. We show how the 2 biggest US tobacco companies, Philip Morris and RJ Reynolds, and their trade association coordinated in mobilizing ideologically diverse constituencies to help defeat the Clinton plan. Unwittingly perhaps, some reform supporters advanced the tobacco industry's public relations blitz, contributing to perceptions of public opposition to the plan. As the current reform debate unfolds, this case highlights the importance of funding transparency for interpreting the activities of think tanks, advocacy groups, and “grassroots” movements. PMID:20466958
PySpike-A Python library for analyzing spike train synchrony
NASA Astrophysics Data System (ADS)
Mulansky, Mario; Kreuz, Thomas
Understanding how the brain functions is one of the biggest challenges of our time. The analysis of experimentally recorded neural firing patterns (spike trains) plays a crucial role in addressing this problem. Here, the PySpike library is introduced, a Python package for spike train analysis providing parameter-free and time-scale independent measures of spike train synchrony. It allows to compute similarity and dissimilarity profiles, averaged values and distance matrices. Although mainly focusing on neuroscience, PySpike can also be applied in other contexts like climate research or social sciences. The package is available as Open Source on Github and PyPI.
The turbulent formation of stars
NASA Astrophysics Data System (ADS)
Federrath, Christoph
2018-06-01
How stars are born from clouds of gas is a rich physics problem whose solution will inform our understanding of not just stars but also planets, galaxies, and the universe itself. Star formation is stupendously inefficient. Take the Milky Way. Our galaxy contains about a billion solar masses of fresh gas available to form stars-and yet it produces only one solar mass of new stars a year. Accounting for that inefficiency is one of the biggest challenges of modern astrophysics. Why should we care about star formation? Because the process powers the evolution of galaxies and sets the initial conditions for planet formation and thus, ultimately, for life.
Ordinal pattern statistics for the assessment of heart rate variability
NASA Astrophysics Data System (ADS)
Graff, G.; Graff, B.; Kaczkowska, A.; Makowiec, D.; Amigó, J. M.; Piskorski, J.; Narkiewicz, K.; Guzik, P.
2013-06-01
The recognition of all main features of a healthy heart rhythm (the so-called sinus rhythm) is still one of the biggest challenges in contemporary cardiology. Recently the interesting physiological phenomenon of heart rate asymmetry has been observed. This phenomenon is related to unbalanced contributions of heart rate decelerations and accelerations to heart rate variability. In this paper we apply methods based on the concept of ordinal pattern to the analysis of electrocardiograms (inter-peak intervals) of healthy subjects in the supine position. This way we observe new regularities of the heart rhythm related to the distribution of ordinal patterns of lengths 3 and 4.
NASA Technical Reports Server (NTRS)
Anderson, Brenda Lindley
2011-01-01
Many studies of mishaps show that human error is a factor in a significant majority of accidents. Trying to decide how to change human behavior to be safer is generally the biggest challenge of any safety program. However, understanding the human psyche is the first step to changing behavior. Many studies focus on the before and after of an accident, but what about the thoughts of a person in the commission of an unsafe act? This is a less understood area. Examining it reveals why it is not well comprehended. This paper attempts to examine a part of the thought process, with an eye to helping influence people to less hurtful actions.
Destination Deimos: A Design Reference Architecture for Initial Human Exploration of the Mars System
NASA Technical Reports Server (NTRS)
Logan, James S.; Adamo, D. R.
2011-01-01
The two biggest challenges to successful human operations in interplanetary space are flight dynamics, constrained by the cold hard physics of the rocket equation, and bioastronautics, the psychophysiological realities of human adaptation, or lack thereof, to the deep space environment. Without substantial innovation in project/mission architecture and vehicle design, human exploration of the Mars system could be problematic for decades. Although a human landing on Mars is inevitable, humans-in-the-loop telerobotic exploration from the outer Martian moon Deimos is the best way to begin. Precursor robotic missions for reconnaissance and local site preparation will be required.
Principles of Statistics: What the Sports Medicine Professional Needs to Know.
Riemann, Bryan L; Lininger, Monica R
2018-07-01
Understanding the results and statistics reported in original research remains a large challenge for many sports medicine practitioners and, in turn, may be among one of the biggest barriers to integrating research into sports medicine practice. The purpose of this article is to provide minimal essentials a sports medicine practitioner needs to know about interpreting statistics and research results to facilitate the incorporation of the latest evidence into practice. Topics covered include the difference between statistical significance and clinical meaningfulness; effect sizes and confidence intervals; reliability statistics, including the minimal detectable difference and minimal important difference; and statistical power. Copyright © 2018 Elsevier Inc. All rights reserved.
Voicing the Challenges Faced by an Innovative Teacher Community
ERIC Educational Resources Information Center
Moate, Josephine
2011-01-01
This research draws on sociocultural theories of learning and activity theory to explore the challenges faced by an innovative community of teachers in Central Finland. The aim of the teacher community was to develop a stream of foreign-language (FL)-mediated teaching and learning in the locality from kindergarten to upper secondary level. To…
ERIC Educational Resources Information Center
Mahfoodh, Omer Hassan Ali
2014-01-01
This paper reports a qualitative study which examines the challenges faced by six international undergraduate students in their socialisation of oral academic discourse in a Malaysian public university. Data were collected employing interviews. Students' presentations were also collected. Semi-structured interviews were transcribed verbatim and…
ERIC Educational Resources Information Center
Livy, Sharyn; Muir, Tracey; Downton, Ann
2017-01-01
One of the challenges facing teacher educators is providing our pre-service teachers (PSTs) with authentic experiences that cross the boundaries between Initial Teacher Education (ITE) and the classroom. An additional challenge facing the mathematics teacher educator, is addressing and deepening PSTs' mathematical content knowledge (MCK), which…
2004-05-03
A special thanks to all of these folks (Glenn Starnes, Lee Gutierrez, Bill Rapp, Joel Hillison, Carlos Gomez, Steve Fraunfelter, Janie Hopkins, Dave ...DiClemente, Joe Nunez, John Bonin , and Steve Nerheim). viii INFORMATION TECHNOLOGY CHALLENGES FACING THE STRATEGIC LEADERS OF HOMELAND SECURITY IN THE 21ST
Strategies for the Challenges Facing Women in Higher Education Administration.
ERIC Educational Resources Information Center
Rehnke, Mary Ann
Women administrators in higher education must deal not only with the usual challenges facing administrators (decision-making, resolving conflict, and advancing professionally), but also with the effects of sex stereotyping. Women are not seen as decision-makers, nor as conflict-resolvers, and are often viewed as supporting personnel rather than…
ERIC Educational Resources Information Center
Rosenberg, Melissa A.
2013-01-01
Women in academia navigate multiple professional and personal roles, and may face unique challenges to integrate their intellectual, emotional, physical, and spiritual selves. The narrative of constraint underscores the disadvantages, challenges, and inequities that women who are mothers and academics face in their lives. This lack of privilege…
Integration and Career Challenges of Newcomer Youth in Newfoundland in Canada
ERIC Educational Resources Information Center
Li, Xuemei; Que, Hua
2016-01-01
Faced with a labor shortage and low profile of diversity, the province of Newfoundland and Labrador in Canada has been making an effort to attract and retain newcomers. Guided by Bronfenbrenner's (1979) ecological systems theory, this qualitative study investigates the challenges faced by newcomer youth, including permanent residents coming as…
ERIC Educational Resources Information Center
de Lange, Paul; Watty, Kim
2011-01-01
Of the various reports released in 2010, two purport to examine the state of accounting education in Australia. These are "Accounting Education at a Crossroad in 2010" and "Challenges Facing Accounting Education in Australia". Both were released as collaborations of the leading academic organisation, the Accounting and Finance…
A Business Intelligence Framework for Sustainability Information Management in Higher Education
ERIC Educational Resources Information Center
Scholtz, Brenda; Calitz, Andre; Haupt, Ross
2018-01-01
Purpose: Higher education institutions (HEIs) face a number of challenges in effectively managing and reporting on sustainability information, such as siloes of data and a limited distribution of information. Business intelligence (BI) can assist in addressing the challenges faced by organisations. The purpose of this study was to propose a BI…
Active Learning: Engaging Students to Maximize Learning in an Online Course
ERIC Educational Resources Information Center
Khan, Arshia; Egbue, Ona; Palkie, Brooke; Madden, Janna
2017-01-01
Student engagement is key to successful teaching and learning, irrespective of the content and format of the content delivery mechanism. However, engaging students presents a particular challenge in online learning environments. Unlike face-to-face courses, online courses present a unique challenge as the only social presence between the faculty…
Can Free-Range Students Save Some Schools? A Case Study on a Hybrid Classroom
ERIC Educational Resources Information Center
White, Christopher Francis
2013-01-01
In the face of budgetary constraints, new marketplace competition, digital innovation and an emerging generation of students with new demands and new needs, higher education in America is challenged as never before. This paper reviews the various challenges facing traditional non-profit educational institutions, considers the potential of an…
Calculus Challenges: An Active Learning Approach
ERIC Educational Resources Information Center
Crawford, Pam; Moseley, Daniel; Nancarrow, Mike; Ward, Erika
2018-01-01
One of the greatest challenges facing students new to calculus is the ability to persevere in the face of failure. Whether the student is choosing an integration technique or a series test, calculus is often the first course in mathematics where the path to the solution is not prescribed in an algorithmic way. At Jacksonville University we…
Challenges Faced by Institutions of Higher Education in Migrating to Distance Learning.
ERIC Educational Resources Information Center
Broskoske, Stephen L.; Harvey, Francis A.
This paper presents the results of a research study conducted in fall 1999 to examine the challenges facing higher educational institutions in migrating to distance learning. The study consisted of five case studies conducted at higher educational institutions in Pennsylvania. At each institution the researchers interviewed the president and other…
The Complexity of Substantive Reform: A Call for Interdependence among Key Stakeholders.
ERIC Educational Resources Information Center
Young, Michelle D.; Petersen, George J.; Short, Paula M.
The field of educational leadership faces serious challenges in the 21st century, such as the shortage of principals and superintendents, the growing demands for leadership positions, and the struggle for adequate resources. This paper explores the challenges facing this field from the position of university educational leadership preparation. The…
ERIC Educational Resources Information Center
Curtis, Michael J.; Batsche, George M.
1991-01-01
Notes that graduate training programs face challenges, as well as opportunities, in fulfillment of their responsibilities to prepare school psychologists for entry into professional practice. Examines nature and origins of potential changes facing school psychology and discusses adequacy of current training programs. Discusses future implications…
Community Violence Exposure of Southeast Asian American Adolescents
ERIC Educational Resources Information Center
Ho, Joyce
2008-01-01
Southeast Asian adolescents in the United States face the daily challenge of adjusting to the American culture and their culture of origin. However, little is known about how the patterns of their bicultural adjustment influence psychological symptoms, especially when faced with other challenges such as community violence and negative life events.…
Preserving Guam's Culture with Culturally Responsive Children's Stories
ERIC Educational Resources Information Center
Jackson, Marilyn Malloy; Heath, Melissa Allen
2017-01-01
Regardless of where schools are located, teachers face the challenge of teaching and mentoring children, not only in academic achievement but in social emotional development. When faced with challenges, young children are especially vulnerable because they lack the life experience and developmental maturity to adequately cope. Relying on the lead…
New Challenges Facing Universities in the Internet-Driven Global Environment
ERIC Educational Resources Information Center
Rajasingham, Lalita
2011-01-01
This paper explores some new challenges facing universities in a global multimediated Internet-based environment, as they seek alternative paradigms and options to remain true to their core business. At a time of rapid technological change, and contested, complex concepts associated with globalisation, knowledge is becoming a primary factor of…
ERIC Educational Resources Information Center
Palombaro, Kerstin M.; Dole, Robin L.; Black, Jill D.
2015-01-01
Introduction and Background: The link between cultural competence and effective physical therapy encounters is established. Physical therapist educational programs face the challenge of fostering the cultural competence of students in effective and meaningful ways within the curriculum. They also face the challenge of measuring the development of…
ERIC Educational Resources Information Center
Scott, David A.; Belke, Stephanie L.; Barfield, Hannah G.
2011-01-01
The number of transgender college students continues to increase every year. These students face unique challenges that many college and university career centers are not prepared to handle. This article describes some of the challenges facing transgender students and college career centers. A professional development design is proposed to assist…
Quality Assurance Challenges and Opportunities Faced by Private Universities in Zimbabwe
ERIC Educational Resources Information Center
Garwe, Evelyn Chiyevo
2014-01-01
The study sought to provide an understanding of the quality assurance challenges and opportunities faced by private universities in Zimbabwe. The study analyzed the factors determining provision of quality higher education in private universities and the resultant effects of failing to achieve the minimum acceptable standards. The author employed…
Challenges and Opportunities Facing Technology Education in Taiwan
ERIC Educational Resources Information Center
Lee, Lung-Sheng Steven
2009-01-01
The technology education in Taiwan is prescribed in the national curriculum and provided to all students in grades 1-12. However, it faces the following challenges: (1) Lack of worthy image, (2) Inadequate teachers in elementary schools, (3) Deficient teaching vitality in secondary schools, and (4) Diluted technology teacher education programs. In…
ERIC Educational Resources Information Center
Bossér, Ulrika; Lundin, Mattias; Lindahl, Mats; Linder, Cedric
2015-01-01
Teachers may face considerable challenges when implementing socio-scientific issues (SSI) in their classroom practices, such as incorporating student-centred teaching practices and exploring knowledge and values in the context of socioscientific issues. This year-long study explores teachers' reflections on the process of developing their…
Challenges Facing Women Academic Leadership in Secondary Schools of Irbid Educational Area
ERIC Educational Resources Information Center
Al-Jaradat, Mahmoud Khaled Mohammad
2014-01-01
This study aimed at identifying the challenges facing women academic leadership in secondary schools of Irbid Educational Area. A random sample of 187 female leaders were chosen. They responded to a 49-item questionnaire prepared by the researcher. The items were distributed into four domains: organizational, personal, social and physical…
Executive Leadership: Another Lever in the System?
ERIC Educational Resources Information Center
Harris, Alma; Brown, David; Abbott, Ian
2006-01-01
The leadership challenges facing most head teachers can at times be daunting but for those leading schools in difficulty, the challenges are acute. This article draws upon the personal experience of an executive leader in a school facing difficult circumstances. It will firstly, outline and analyse this model of leadership and secondly, look at…
TQM in a Multi-Campus Public University.
ERIC Educational Resources Information Center
Zargar, Ali M.
Running a university is fast becoming more challenging than managing a large corporation, in part due to greater quality demands by more groups in the face of shrinking resources and budget cuts. This paper argues against universities conducting business as usual in the face of societal change and increasingly greater challenges, and presents…
Challenges in healthcare delivery in an economic downturn, in the Republic of Ireland.
Carney, Marie
2010-07-01
The purpose of the present study was to discuss some of effects of the downturn in the Irish economy and to demonstrate that in the face of economic difficulties innovation in health care is still occurring. Staff that are managing and delivering healthcare need to know the challenges facing them and have an awareness of the importance of maintaining interest in innovative practice in turbulent times. Information obtained from several sources including government papers, the nursing regulatory board and quality authority documents and current best practice articles. Information was evaluated based on the study's aim. Issues emerging were that current challenges facing Irish health care delivery relate mainly to economic, clinical management, education and information technology factors and further reductions in the cost base of health care delivery remains focused on value for money. In the face of the economic downturn Ireland is achieving health targets and is now sitting in 13th place on the European health index, down from number 28 in 2008. This improvement in position has resulted from several new innovative work practices. As a result of cost reduction measures in place nurse managers will face greater challenges than ever before in meeting the objectives of the healthcare transformation programme.
Web-Based vs. Face-to-Face MBA Classes: A Comparative Assessment Study
ERIC Educational Resources Information Center
Brownstein, Barry; Brownstein, Deborah; Gerlowski, Daniel A.
2008-01-01
The challenges of online learning include ensuring that the learning outcomes are at least as robust as in the face-to-face sections of the same course. At the University of Baltimore, both online sections and face-to-face sections of core MBA courses are offered. Once admitted to the MBA, students are free to enroll in any combination of…
ERIC Educational Resources Information Center
Weiner, Jill
2005-01-01
In this article, the author discusses "Game Face: Life Lessons Across the Curriculum", a teaching kit that challenges assumptions and builds confidence. Game Face, which is derived from a book and art exhibition, "Game Face: What Does a Female Athlete Look Like?", uses layered and powerful images of women and girls participating in sports to teach…
Thermal-to-visible face recognition using partial least squares.
Hu, Shuowen; Choi, Jonghyun; Chan, Alex L; Schwartz, William Robson
2015-03-01
Although visible face recognition has been an active area of research for several decades, cross-modal face recognition has only been explored by the biometrics community relatively recently. Thermal-to-visible face recognition is one of the most difficult cross-modal face recognition challenges, because of the difference in phenomenology between the thermal and visible imaging modalities. We address the cross-modal recognition problem using a partial least squares (PLS) regression-based approach consisting of preprocessing, feature extraction, and PLS model building. The preprocessing and feature extraction stages are designed to reduce the modality gap between the thermal and visible facial signatures, and facilitate the subsequent one-vs-all PLS-based model building. We incorporate multi-modal information into the PLS model building stage to enhance cross-modal recognition. The performance of the proposed recognition algorithm is evaluated on three challenging datasets containing visible and thermal imagery acquired under different experimental scenarios: time-lapse, physical tasks, mental tasks, and subject-to-camera range. These scenarios represent difficult challenges relevant to real-world applications. We demonstrate that the proposed method performs robustly for the examined scenarios.
Dalton, Vanessa K; Jacobson, Peter D; Berson-Grand, Julie; Weisman, Carol S
2005-01-01
Title X is the only federal funding specifically for contraception and family planning services. This study identifies the threats and challenges Title X family planning organizations face in Michigan, and examines organizational responses to these challenges. We hypothesized that organizational responses to current challenges, including recent legislation, would differ between organizational types. We used a multiple case study design to examine safety net providers that received Title X funding in 2001. Cases were selected to represent economic and geographic diversity and included a mix of population densities. Key informants at each organization participated in face-to-face, semistructured interviews. Interviews collected data on current challenges, organizational planning processes, and organizational responses. All Title X organizations reported significant challenges, including rising costs, increasing need, and inadequate funding. Private organizations were more concerned about political challenges, especially recent Michigan legislation, than health departments. Organizational type was associated with the type of response. Health departments tended to close clinics or cut services, whereas private organizations recruited insured populations and increased patient fees. Based on these findings, the family planning safety net in Michigan appears to be undergoing significant change. These changes may decrease the availability of affordable family planning services in Michigan.
2001-01-01
Background The study is designed to assess the organisational and human resource challenges faced by Primary Care Trusts (PCTs). Its objectives are to: specify the organisational and human resources challenges faced by PCTs in fulfilling the roles envisaged in government and local policy; examine how PCTs are addressing these challenges, in particular, to describe the organisational forms they have adopted, and the OD/HR strategies and initiatives they have planned or in place; assess how effective these structures, strategies and initiatives have been in enabling the PCTs to meet the organisational and human resources challenges they face; identify the factors, both internal to the PCT and in the wider health community, which have contributed to the success or failure of different structures, strategies and initiatives. Methods The study will be undertaken in three stages. In Stage 1 the key literature on public sector and NHS organisational development and human resources management will be reviewed, and discussions will be held with key researchers and policy makers working in this area. Stage 2 will focus on detailed case studies in six PCTs designed to examine the organisational and human resources challenges they face. Data will be collected using semi-structured interviews, group discussion, site visits, observation of key meetings and examination of local documentation. The findings from the case study PCTs will be cross checked with a Reference Group of up to 20 other PCG/Ts, and key officers working in organisational development or primary care at local, regional and national level. In Stage 3 analysis of findings from the preparatory work, the case studies and the feedback from the Reference Group will be used to identify practical lessons for PCTs, key messages for policy makers, and contributions to further theoretical development. PMID:11737883
Healthy ageing supported by technology--a cross-disciplinary research challenge.
Koch, Sabine
2010-01-01
During the last decade, the challenges of an ageing society became focus for extensive scientific, public and political discussions. From discussions in scientific fora within each discipline, there is now a shift towards cross-disciplinary scientific approaches. The aim of this article is therefore, to collect and describe different scientific viewpoints in this regard and to point out research gaps to be addressed in the future. The article is based on a number of review articles and keynote lectures given by the author, and complemented with informal interviews of experts from different scientific fields engaged in the field of technology and ageing. Results show that research has emerged from being technology-focussed to scenario-based taking different scientific perspectives into account. However, the biggest challenge still is to accommodate the need for a holistic integrated service which means to provide personalised services and adapt technology and content to individual needs of different stakeholders. Further, cross-disciplinary research is needed that relates informatics and technology to different stages of the aging process and that evaluates the effects of proposed technical solutions.
Pan, Xueni; Hamilton, Antonia F de C
2018-03-05
As virtual reality (VR) technology and systems become more commercially available and accessible, more and more psychologists are starting to integrate VR as part of their methods. This approach offers major advantages in experimental control, reproducibility, and ecological validity, but also has limitations and hidden pitfalls which may distract the novice user. This study aimed to guide the psychologist into the novel world of VR, reviewing available instrumentation and mapping the landscape of possible systems. We use examples of state-of-the-art research to describe challenges which research is now solving, including embodiment, uncanny valley, simulation sickness, presence, ethics, and experimental design. Finally, we propose that the biggest challenge for the field would be to build a fully interactive virtual human who can pass a VR Turing test - and that this could only be achieved if psychologists, VR technologists, and AI researchers work together. © 2018 The Authors British Journal of Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.
Joginder Singh, Susheel; Hussein, Nur Hazirah; Mustaffa Kamal, Rahayu; Hassan, Fatimah Hani
2017-06-01
Parents play an important role in the successful implementation of AAC. Previous research has indicated that parents in different countries have varying perceptions about the use of AAC and face different challenges in its implementation. To date, there is limited information about the use of AAC by children in Malaysia or parents' views about its use. The aim of this study was to explore Malaysian parents' perception of AAC and their experience when supporting their children who use AAC. For this study, 12 parents of children with autism spectrum disorder and cerebral palsy were involved in semi-structured individual interviews. Qualitative content analysis was used to analyze interview data. Following analysis, three themes were identified: (a) impact of the use of AAC, (b) challenges faced, and (c) hopes and expectations. Participants reported that the use of AAC had a positive impact on their children, but that they faced challenges related to the child, the settings, and the system itself, as well as a lack of time and support. Findings from this study provide an insight for Malaysian speech therapists about the challenges faced by parents when supporting their children who use AAC, and how important it is to overcome these challenges to ensure successful implementation of AAC.
Abou-Gharbia, Magid; Childers, Wayne E
2013-07-25
The pharmaceutical industry is facing enormous challenges, including reduced efficiency, declining innovation, key patent expirations, fierce price competition from generics, high regulatory hurdles, and a tarnished image. There is a clear need for change in the paradigms designed to address these challenges. Pharma has responded by embarking on a range of initiatives. However, along the way the industry has accrued critics whose accusations have tainted its reputation. The first part of this two-part series will discuss the criticisms that have been leveled at the pharmaceutical industry and summarize the supporting data for and against these criticisms. The second installment will focus on the current challenges facing the pharmaceutical industry and Pharma's responses to address these challenges. It will describe the industry's changing perspective and new business models for coping with the recent loss of talent and declining clinical pipelines as well as present some examples of recent drug discovery successes.
ERIC Educational Resources Information Center
Durning, Steven J.; Artino, Anthony R.; Holmboe, Eric; Beckman, Thomas J.; van der Vleuten, Cees; Schuwirth, Lambert
2010-01-01
The demands of physician practice are growing. Some specialties face critical shortages and a significant percentage of physicians are aging. To improve health care it is paramount to understand and address challenges, including cognitive issues, facing aging physicians. In this article, we outline several issues related to cognitive performance…
Raising the Cash: A Study of the Role of Leadership in a Capital Campaign
ERIC Educational Resources Information Center
Diaz, Sandra L.
2013-01-01
Institutions of higher education are facing a number of challenges as they compete in the new global economy. Many of these institutions face increasing internal and external challenges, all of which involve additional expenses at a time when resources are diminishing. With growing financial uncertainties caused by fluctuating financial markets…
ERIC Educational Resources Information Center
National Center on Secondary Education and Transition (NCSET), University of Minnesota, 2004
2004-01-01
This paper is intended to promote discussion among professionals, policymakers, employers, parents, and individuals with disabilities concerning current and future challenges facing secondary education and transition services nationally. The issues identified and discussed should not, however, be viewed as inclusive of the full range of possible…
ERIC Educational Resources Information Center
Eton, Marus; Mwirumubi, Richard; Edaku, Charles
2017-01-01
Entrepreneurship is defined as the process where an individual discovers, evaluates and exploit opportunities independently. Most countries have embraced entrepreneurship development as ways of creating employment and economic growth and development. The objective of the study was to examine the challenges faced by commercial enterprises in Lira…
On-Line Literature: The Challenge of Integrating Web-Based Materials
ERIC Educational Resources Information Center
Ruzich, Constance M.
2012-01-01
This classroom research discusses the challenges of integrating face-to-face interactions with the use of on-line resources in secondary English classrooms. Examining the lesson plans of pre-service and early career teachers in the US, I found that the uses of on-line resources were frequently neither coherent nor consistent with the goals and…
The Resonance Factor: Probing the Impact of Video on Student Retention in Distance Learning
ERIC Educational Resources Information Center
Geri, Nitza
2012-01-01
Teaching and instructing is one of the challenging manifestations of informing, within which distance learning is considered harder than face-to-face instruction. Student retention is one of the major challenges of distance learning. Current innovative technologies enable widespread use of video lectures that may ease the loneliness of the…
Rural Teachers' Views: What Are Gender-Based Challenges Facing Free Primary Education in Lesotho?
ERIC Educational Resources Information Center
Morojele, Pholoho
2013-01-01
This paper gives prominence to rural teachers' accounts of gender-based challenges facing Free Primary Education in Lesotho. It draws on feminist interpretations of social constructionism to discuss factors within the Basotho communities that affect gender equality in the schools. The inductive analysis offered makes use of the data generated from…
Challenges Facing Canadian Federal Offenders Newly Released to the Community: A Concept Map
ERIC Educational Resources Information Center
Brown, Jason D.
2004-01-01
The purpose of the study was to describe the needs of newly released Canadian federal offenders as perceived by community parole supervisors. Seventy-four Canadian parole supervisors were asked to answer the following question: "What challenges do parolees face in the first 90 days after release?" The data were analyzed using…
Children at Risk of Neglect: Challenges Faced by Child Protection Practitioners in Guatemala City
ERIC Educational Resources Information Center
Coope, Caroline M.; Theobald, Sally
2006-01-01
Objectives: The objectives were to (1) delineate the definition, common forms, and perceived risk factors contributing to child neglect in Guatemala from the perspective of different stakeholders and (2) identify the challenges faced by child protection practitioners in identifying children at risk of neglect within the context of Guatemala.…
Madrasa Education in South Asia and Southeast Asia: Current Issues and Debates
ERIC Educational Resources Information Center
Park, Jaddon; Niyozov, Sarfaroz
2008-01-01
Madaris (plural of madrasa) face a multitude of challenges in preparing students for life in rapidly modernising societies and emerging globalised knowledge economies. The complexity of the role and tasks of madaris, which are caught in the interface of modernity and tradition, the challenges they face, and the strategies they develop to address…
ERIC Educational Resources Information Center
Bullock, Lyndal M.; Gable, Robert A.; Carrero, Kelly; Lewis, Calli; Collins, Emerald; Zolkowski, Staci; Lusk, Mandy
2014-01-01
American schools are witnessing the increasing cultural heterogeneity of our nation's population. Educators are faced with the challenge of ensuring positive educational outcomes for all students, despite the lack of empirical understanding of how to effectively educate culturally and linguistically diverse learners. The purpose of this paper is…
Managing Digital Identity on Twitter: The Case of School Administrators
ERIC Educational Resources Information Center
Cho, Vincent; Jimerson, Jo Beth
2017-01-01
What does it mean to be and to act like a school leader online? Although many school leaders might be comfortable navigating issues of identity in face-to-face environments, online environments may present new and unprecedented challenges. These challenges may range from concerns about privacy and surveillance to questions about how best to…
The Health Challenges of Urban Latino College Students as Revealed through Student Journaling
ERIC Educational Resources Information Center
Rowland, Amy L.
2008-01-01
Because of the unique health risks faced by the Hispanic population and the notoriously poor health habits of college students, this study examines the health challenges faced by Latino college students enrolled at an urban commuter institution. A thematic analysis reveals the top themes for males and females as healthy eating, weight management,…
ERIC Educational Resources Information Center
De Lisle, Jerome; Seunarinesingh, Krishna; Mohammed, Rhoda; Lee-Piggott, Rinnelle
2017-01-01
In this study, methodology and theory were linked to explicate the nature of education practice within schools facing exceptionally challenging circumstances (SFECC) in Trinidad and Tobago. The research design was an iterative quan>QUAL-quan>qual multi-method research programme, consisting of 3 independent projects linked together by overall…
Challenges of Adopting the Use of Technology in Less Developed Countries: The Case of Cambodia
ERIC Educational Resources Information Center
Richardson, Jayson W.
2011-01-01
Drawing on Everett Rogers's theory of the diffusion of innovations, this article identifies the barriers, challenges, and successes in the adoption of technology training by teacher trainers in Cambodia. The analysis was based on data collected from an open-ended survey, face-to-face interviews, and document analysis. Findings reveal that the…
Introducing Decision Making under Uncertainty and Strategic Considerations in Engineering Design
ERIC Educational Resources Information Center
Kosmopoulou, Georgia; Jog, Chintamani; Freeman, Margaret; Papavassiliou, Dimitrios V.
2010-01-01
Chemical Engineering graduates will face challenges at the workplace that even their peers who graduated a few years ago were not expected to face. One such major challenge is the management and operation of companies and plants under conditions of uncertainty and the need to make decisions in competitive situations. Modern developments in…
Challenges Beginning Teachers Face in Hong Kong
ERIC Educational Resources Information Center
Lam, Bick-Har
2014-01-01
By conducting in-depth interviews with new teachers who are about to become full-time teachers and then reinterviewing them two years later, the author of this article presents how beginning teachers think and feel about teaching and describes the challenges they face as beginning teachers in the context of Hong Kong. The stories of the teachers,…
Challenges Faced by Preceptors Serving in Dual Roles as Health Care Providers and Clinical Educators
ERIC Educational Resources Information Center
Dodge, Thomas; Mazerolle, Stephanie M.; Bowman, Thomas G.
2014-01-01
Context: Preceptors play an integral role in training athletic training students (ATSs). Balancing roles as health care providers and educators can often be challenging. Role strain is a documented concern for the preceptor, yet limited information is available regarding other issues faced while supervising ATSs. Objective: To explore preceptor…
Transition Program: The Challenges Faced by Special Needs Students in Gaining Work Experience
ERIC Educational Resources Information Center
Alias, Aliza
2014-01-01
Transition program for special needs students is known to open opportunities for students with learning disabilities to gain work experience in actual work environment. The program provides training activities and also an opportunity to go for internship to gain work experience. Therefore, this study is to identify the challenges faced by special…
Accommodating Extension Clients Who Face Language, Vision, or Hearing Challenges
ERIC Educational Resources Information Center
Angima, Sam; Etuk, Lena; Maddy, Deborah
2016-01-01
A survey-based study explored approaches used by one land-grant university to meet the needs of Extension clients who face language, vision, or hearing challenges. In attempts to serve such clients, the greatest gaps existed for clients whose main language was Spanish, followed by those who had vision impairments and then those who had hearing…
Single Black Working Mothers' Perceptions: The Journey to Achieve Leadership Positions
ERIC Educational Resources Information Center
Raglin, Sherrell
2017-01-01
Single Black working mothers faced significant challenges in achieving high-level or senior-level leadership positions. The purpose of this qualitative narrative study was to collect, analyze and code the stories told by 10 participants to understand the perceptions and insights of the challenges and barriers single Black working mothers faced in…
ERIC Educational Resources Information Center
Powers, Wendy A.
2014-01-01
Modern higher education institutions face tremendous challenges, including dwindling financial resources, waning public support, demands for greater accountability, and daunting student needs and expectations. Campus presidents simply cannot face these challenges as isolated or solitary leaders. High functioning, inclusive, collaborative, and…
Lost in Translation: Adapting a Face-to-Face Course Into an Online Learning Experience.
Kenzig, Melissa J
2015-09-01
Online education has grown dramatically over the past decade. Instructors who teach face-to-face courses are being called on to adapt their courses to the online environment. Many instructors do not have sufficient training to be able to effectively move courses to an online format. This commentary discusses the growth of online learning, common challenges faced by instructors adapting courses from face-to-face to online, and best practices for translating face-to-face courses into online learning opportunities. © 2015 Society for Public Health Education.
Assessing Student Performance and Perceptions in Lecture Capture vs. Face-to-Face Course Delivery
ERIC Educational Resources Information Center
Euzent, Patricia; Martin, Thomas; Moskal, Patrick; Moskal, Patsy
2011-01-01
Public universities are currently facing a challenge in determining how to deliver quality instruction in the face of severe fiscal constraints. With recent technological advances, courses streamed over the Internet (i.e., lecture capture) are now becoming common. However, little research has been published that specifically examines student…
The Challenges of Pharmacy Education in Yemen
2014-01-01
Pharmacy education in Yemen has faced many challenges since its introduction in the 1980s. Most Yemeni pharmacy schools, especially private ones, are experiencing difficulties in providing the right quality and quantity of clinical educational experiences. Most of these challenges are imbedded in a teaching style and curricula that have failed to respond to the needs of the community and country. The slow shift from traditional drug-dispensing to a patient-centered or focused approach in pharmacy practice requires a fundamental change in the roles and responsibilities of both policymakers and educators. The purpose of this paper is twofold: (1) to discuss the challenges facing the pharmacy education in Yemen; (2) to provided recommendations to overcome challenges. PMID:25386011
Abnormal GABAergic function and face processing in schizophrenia: A pharmacologic-fMRI study.
Tso, Ivy F; Fang, Yu; Phan, K Luan; Welsh, Robert C; Taylor, Stephan F
2015-10-01
The involvement of the gamma-aminobutyric acid (GABA) system in schizophrenia is suggested by postmortem studies and the common use of GABA receptor-potentiating agents in treatment. In a recent study, we used a benzodiazepine challenge to demonstrate abnormal GABAergic function during processing of negative visual stimuli in schizophrenia. This study extended this investigation by mapping GABAergic mechanisms associated with face processing and social appraisal in schizophrenia using a benzodiazepine challenge. Fourteen stable, medicated schizophrenia/schizoaffective patients (SZ) and 13 healthy controls (HC) underwent functional MRI using the blood oxygenation level-dependent (BOLD) technique while they performed the Socio-emotional Preference Task (SePT) on emotional face stimuli ("Do you like this face?"). Participants received single-blinded intravenous saline and lorazepam (LRZ) in two separate sessions separated by 1-3weeks. Both SZ and HC recruited medial prefrontal cortex/anterior cingulate during the SePT, relative to gender identification. A significant drug by group interaction was observed in the medial occipital cortex, such that SZ showed increased BOLD signal to LRZ challenge, while HC showed an expected decrease of signal; the interaction did not vary by task. The altered BOLD response to LRZ challenge in SZ was significantly correlated with increased negative affect across multiple measures. The altered response to LRZ challenge suggests that abnormal face processing and negative affect in SZ are associated with altered GABAergic function in the visual cortex, underscoring the role of impaired visual processing in socio-emotional deficits in schizophrenia. Copyright © 2015 Elsevier B.V. All rights reserved.
Johansson, Birgitta; Held, Claes; Sjöström, Jonas; Lindahl Norberg, Annika; Hovén, Emma; Sanderman, Robbert; van Achterberg, Theo; von Essen, Louise
2017-01-01
Background U-CARE is a multidisciplinary eHealth research program that involves the disciplines of caring science, clinical psychology, health economics, information systems, and medical science. It was set up from scratch in a university setting in 2010, funded by a governmental initiative. While establishing the research program, many challenges were faced. Systematic documentation of experiences from establishing new research environments is scarce. Objective The aim of this paper was to describe the challenges of establishing a publicly funded multidisciplinary eHealth research environment. Methods Researchers involved in developing the research program U-CARE identified challenges in the formal documentation and by reflecting on their experience of developing the program. The authors discussed the content and organization of challenges into themes until consensus was reached. Results The authors identified 15 major challenges, some general to establishing a new research environment and some specific for multidisciplinary eHealth programs. The challenges were organized into 6 themes: Organization, Communication, Implementation, Legislation, Software development, and Multidisciplinarity. Conclusions Several challenges were faced during the development of the program and several accomplishments were made. By sharing our experience, we hope to help other research groups embarking on a similar journey to be prepared for some of the challenges they are likely to face on their way. PMID:28536090
Taxonomy of Challenges for Digital Forensics.
Karie, Nickson M; Venter, Hein S
2015-07-01
Since its inception, over a decade ago, the field of digital forensics has faced numerous challenges. Despite different researchers and digital forensic practitioners having studied and analysed various known digital forensic challenges, as of 2013, there still exists a need for a formal classification of these challenges. This article therefore reviews existing research literature and highlights the various challenges that digital forensics has faced for the last 10 years. In conducting this research study, however, it was difficult for the authors to review all the existing research literature in the digital forensic domain; hence, sampling and randomization techniques were employed to facilitate the review of the gathered literature. Taxonomy of the various challenges is subsequently proposed in this paper based on our review of the literature. The taxonomy classifies the large number of digital forensic challenges into four well-defined and easily understood categories. The proposed taxonomy can be useful, for example, in future developments of automated digital forensic tools by explicitly describing processes and procedures that focus on addressing specific challenges identified in this paper. However, it should also be noted that the purpose of this paper was not to propose any solutions to the individual challenges that digital forensics face, but to serve as a survey of the state of the art of the research area. © 2015 American Academy of Forensic Sciences.
Hyperspectral face recognition with spatiospectral information fusion and PLS regression.
Uzair, Muhammad; Mahmood, Arif; Mian, Ajmal
2015-03-01
Hyperspectral imaging offers new opportunities for face recognition via improved discrimination along the spectral dimension. However, it poses new challenges, including low signal-to-noise ratio, interband misalignment, and high data dimensionality. Due to these challenges, the literature on hyperspectral face recognition is not only sparse but is limited to ad hoc dimensionality reduction techniques and lacks comprehensive evaluation. We propose a hyperspectral face recognition algorithm using a spatiospectral covariance for band fusion and partial least square regression for classification. Moreover, we extend 13 existing face recognition techniques, for the first time, to perform hyperspectral face recognition.We formulate hyperspectral face recognition as an image-set classification problem and evaluate the performance of seven state-of-the-art image-set classification techniques. We also test six state-of-the-art grayscale and RGB (color) face recognition algorithms after applying fusion techniques on hyperspectral images. Comparison with the 13 extended and five existing hyperspectral face recognition techniques on three standard data sets show that the proposed algorithm outperforms all by a significant margin. Finally, we perform band selection experiments to find the most discriminative bands in the visible and near infrared response spectrum.
Challenges Pre-Service Teachers Face When Implementing a 5E Inquiry Model of Instruction
ERIC Educational Resources Information Center
Enugu, Ramya; Hokayem, Hayat
2017-01-01
This study examined the challenges that pre-service teachers faced when implementing inquiry and their perspective on how to overcome them. The data sample was 55 pre-service teachers (PSTs) enrolled into two sections of a science methods course in a private university in North Texas. The data sources consisted of inquiry-based lesson plans, PST…
ERIC Educational Resources Information Center
Hirsch, Werner Z., Ed.; Weber, Luc E., Ed.
This collection of 17 essays focuses on the major changes that higher education needs to make so that it can effectively pursue teaching and research and significantly contribute public service in a rapidly changing world. The essays include: (1) "Survey of the Main Challenges Facing Higher Education at the Millennium" (Luc E. Weber);…
ERIC Educational Resources Information Center
Flannery, K. B.; Fenning, P.; Kato, M. McGrath; McIntosh, K.
2014-01-01
High school is an important time in the educational career of students. It is also a time when adolescents face many behavioral, academic, and social-emotional challenges. Current statistics about the behavioral, academic, and social-emotional challenges faced by adolescents, and the impact on society through incarceration and dropout, have…
ERIC Educational Resources Information Center
Wangila, Violet Muyoka
2017-01-01
This paper scrutinises the challenges facing the implementation of Early Childhood Development and Education policy in Bungoma County, Kenya. The study used a mixed research design and study population comprised of the QASOs, the Head teachers, ECDE teachers and the non-teaching staff in respective ECDCs. The sample size of the study comprised of…
A Short Twenty Years: Meeting the Challenges Facing Teachers Who Bring Rwanda into the Classroom
ERIC Educational Resources Information Center
Gudgel, Mark
2013-01-01
As the twentieth anniversary of the 1994 genocide in Rwanda approaches, Mark Gudgel argues that we should face the challenges posed by teaching about Rwanda. Drawing on his experience as a history teacher in the US, his experience researching and supporting others' classrooms in the US and UK, his training in Holocaust education and his knowledge…
Executive Programs for Brazilian Mid-Career Public Managers: Pitfalls and Challenges
ERIC Educational Resources Information Center
Pacheco, Regina Silvia; Franzese, Cibele
2017-01-01
This paper discusses the challenges of professional education for mid-career public managers at graduate level, pointing out pitfalls to avoid and obstacles to face. Analyzing the Brazilian case, the goal is to raise issues that may also be present in other cases. The main argument developed here is that the puzzle faced by graduate programs on…
ERIC Educational Resources Information Center
Nelson, Bethany; Froehner, Megan; Gault, Barbara
2013-01-01
This paper discusses the challenges college students with children face, as well as the steps colleges, universities, and the surrounding communities must take to help students succeed in their work as both students and parents. The role of parenthood in postsecondary settings needs greater focus from the higher education reform community. Unless…
ERIC Educational Resources Information Center
Johnson, Clarence; Kritsonis, William Allan
2007-01-01
School systems in America face many critical challenges pertaining to regulating cell phone use by students in today's schools. School executives and classroom teachers face challenges daily relative to how to effectively deal with student's using cell phones. There are many drawbacks and benefits for cell phone use by students. The authors…
ERIC Educational Resources Information Center
Schoel, Jim; Butler, Steve; Murray, Mark; Gass, Mike; Carrick, Moe
2001-01-01
Presents five group problem-solving initiatives for use in adventure and experiential settings, focusing on conflict resolution, corporate workplace issues, or adjustment to change. Includes target group, group size, time and space needs, activity level, overview, goals, props, instructions, and suggestions for framing and debriefing the…
ERIC Educational Resources Information Center
Jean-Marie, Gaetane
2013-01-01
While all educational leaders face challenges in achieving success, African American female principals often face a unique set of challenges associated with the complexity of their gender, race, and, as examined in this study, age. This case study investigates the experiences of two highly visible, early career African American female principals…
ERIC Educational Resources Information Center
Cruickshank, Vaughan; Pedersen, Scott; Hill, Allen; Callingham, Rosemary
2015-01-01
The gender-related challenges facing males entering the primary-school teaching profession have been well documented in the academic literature over recent decades. The majority of these data have come about through qualitative reports. Whilst qualitative methods provide important perspectives into these issues, the use of valid and reliable…
ERIC Educational Resources Information Center
Zajac, Lynne K.
2010-01-01
The nursing profession is calling for enhanced diversity within the ranks of registered nurses to meet the health care needs of an increasingly diverse society. Nursing education is faced with the challenge of retaining ethnically diverse nursing students. Students who are ethnically diverse face unique challenges in addition to the universal…
Support and Defend: The K-12 Education of Military-Connected Children. White Paper No. 131
ERIC Educational Resources Information Center
Wykes, Bruce L.
2015-01-01
Many policies and initiatives have been proposed or implemented to address the unique needs of military families who face special challenges while supporting the service of their military member(s). Some of those policies and initiatives have sought to focus on military-connected children (MCCs) and the particular academic challenges they face.…
ERIC Educational Resources Information Center
Parker, Denise L.
2017-01-01
Virtual teams are comprised of members from various locations who use Information and Communication Technology (ICT) for member interaction. Many organizations have accepted virtual teams as an alternative to face-to-face teams. With the acceptance comes many challenges, one of those challenges is supporting team sharing in the virtual…
The changing face of environmentalism in the Soviet Union
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1990-03-01
Igor Izodorovich Altshuler and Ruben Artyomovich Mnatsakanyan are scientific researchers in the department of geography at Moscow State University and cofounders of the Association for the Support of Ecological initiatives established by the Soviet Foundation for Social Innovations. They authored a report on glasnost and ecology in the Soviet Union published in the December 1988 ENVIRONMENT. Recently, Altshuler and Mnatsakanyan visited ENVIRONMENT's offices in Washington, D.C., and talked at length about environmental problems and issues in the USSR. This paper presents excerpts of an interview of Altshuler and Mnatsakanyan conducted by Barbara Richman, managing editor of ENVIRONMENT. They discuss environmentalmore » problems, global climate change, agriculture, lack of information on the biggest polluters, transboundary pollution, impact of recent elections on environmental policy, the use of environmental impact assessments, public information about the environment, training of reporters, environmental organizations, and lack of money and political obstacles to environmental improvements.« less
VIEWCACHE: An incremental pointer-based access method for autonomous interoperable databases
NASA Technical Reports Server (NTRS)
Roussopoulos, N.; Sellis, Timos
1993-01-01
One of the biggest problems facing NASA today is to provide scientists efficient access to a large number of distributed databases. Our pointer-based incremental data base access method, VIEWCACHE, provides such an interface for accessing distributed datasets and directories. VIEWCACHE allows database browsing and search performing inter-database cross-referencing with no actual data movement between database sites. This organization and processing is especially suitable for managing Astrophysics databases which are physically distributed all over the world. Once the search is complete, the set of collected pointers pointing to the desired data are cached. VIEWCACHE includes spatial access methods for accessing image datasets, which provide much easier query formulation by referring directly to the image and very efficient search for objects contained within a two-dimensional window. We will develop and optimize a VIEWCACHE External Gateway Access to database management systems to facilitate database search.
VIEWCACHE: An incremental pointer-based access method for autonomous interoperable databases
NASA Technical Reports Server (NTRS)
Roussopoulos, N.; Sellis, Timos
1992-01-01
One of biggest problems facing NASA today is to provide scientists efficient access to a large number of distributed databases. Our pointer-based incremental database access method, VIEWCACHE, provides such an interface for accessing distributed data sets and directories. VIEWCACHE allows database browsing and search performing inter-database cross-referencing with no actual data movement between database sites. This organization and processing is especially suitable for managing Astrophysics databases which are physically distributed all over the world. Once the search is complete, the set of collected pointers pointing to the desired data are cached. VIEWCACHE includes spatial access methods for accessing image data sets, which provide much easier query formulation by referring directly to the image and very efficient search for objects contained within a two-dimensional window. We will develop and optimize a VIEWCACHE External Gateway Access to database management systems to facilitate distributed database search.
Villacorta-Linaza, Rocio
2009-10-01
Access to essential medicines remains one of the biggest problems that developing countries are facing in health care systems. Non-governmental organizations (NGOs) are implementing health programmes on the ground in areas affected by natural disasters or conflict. A vital component of these health programmes is the drug supply system. Based on a field research conducted in Pakistan 2007 and a field work experience in Afghanistan within an international NGO-Merlin-this paper analysed the four functions of the Drug Supply Cycle (Selection, Procurement, Distribution and Use) focusing attention on the importance in management support systems once the emergency phase is over. It shows the core role that the pharmacist plays within NGOs as a member of the health staff with the ability to improve the management of the Drug Supply Cycle. Copyright (c) 2009 John Wiley & Sons, Ltd.
Toxic disputes and the rise of environmental justice in Australia.
Lloyd-Smith, Mariann E; Bell, Lee
2003-01-01
The paper examines the rise of environmental justice issues in Australia, evident in two toxic disputes; the first, in a Perth outer suburb in Western Australia where residents faced both a hazardous waste dump and the nation's biggest chemical fire; and the second, in the Sydney suburb of Botany where residents were confronted with the destruction of what is thought to be, the world's largest stockpile of hazardous hexachlorobenzene (HCB) waste. The paper reviews the range of factors that impacted the local communities' fight for environmental justice. It explores the limitations of risk assessment and risk-based policies, as well as the problematic role of the expert and the communication of risk. The informational inequity and resource disparities so evident in toxic disputes are highlighted. The case studies confirmed the inequitable distribution of chemical risk as a failure to secure environmental justice for all Australians.
Supramolecular complexation for environmental control.
Albelda, M Teresa; Frías, Juan C; García-España, Enrique; Schneider, Hans-Jörg
2012-05-21
Supramolecular complexes offer a new and efficient way for the monitoring and removal of many substances emanating from technical processes, fertilization, plant and animal protection, or e.g. chemotherapy. Such pollutants range from toxic or radioactive metal ions and anions to chemical side products, herbicides, pesticides to drugs including steroids, and include degradation products from natural sources. The applications involve usually fast and reversible complex formation, due to prevailing non-covalent interactions. This is of importance for sensing as well as for separation techniques, where the often expensive host compounds can then be reused almost indefinitely. Immobilization of host compounds, e.g. on exchange resins or on membranes, and their implementation in smart new materials hold particular promise. The review illustrates how the design of suitable host compounds in combination with modern sensing and separation methods can contribute to solve some of the biggest problems facing chemistry, which arise from the everyday increasing pollution of the environment.
The quest for improved reproducibility in MALDI mass spectrometry.
O'Rourke, Matthew B; Djordjevic, Steven P; Padula, Matthew P
2018-03-01
Reproducibility has been one of the biggest hurdles faced when attempting to develop quantitative protocols for MALDI mass spectrometry. The heterogeneous nature of sample recrystallization has made automated sample acquisition somewhat "hit and miss" with manual intervention needed to ensure that all sample spots have been analyzed. In this review, we explore the last 30 years of literature and anecdotal evidence that has attempted to address and improve reproducibility in MALDI MS. Though many methods have been attempted, we have discovered a significant publication history surrounding the use of nitrocellulose as a substrate to improve homogeneity of crystal formation and therefore reproducibility. We therefore propose that this is the most promising avenue of research for developing a comprehensive and universal preparation protocol for quantitative MALDI MS analysis. © 2016 Wiley Periodicals, Inc. Mass Spec Rev 37:217-228, 2018. © 2016 Wiley Periodicals, Inc.
Estimation, modeling, and simulation of patterned growth in extreme environments.
Strader, B; Schubert, K E; Quintana, M; Gomez, E; Curnutt, J; Boston, P
2011-01-01
In the search for life on Mars and other extraterrestrial bodies or in our attempts to identify biological traces in the most ancient rock record of Earth, one of the biggest problems facing us is how to recognize life or the remains of ancient life in a context very different from our planet's modern biological examples. Specific chemistries or biological properties may well be inapplicable to extraterrestrial conditions or ancient Earth environments. Thus, we need to develop an arsenal of techniques that are of broader applicability. The notion of patterning created in some fashion by biological processes and properties may provide such a generalized property of biological systems no matter what the incidentals of chemistry or environmental conditions. One approach to recognizing these kinds of patterns is to look at apparently organized arrangements created and left by life in extreme environments here on Earth, especially at various spatial scales, different geologies, and biogeochemical circumstances.
Pollution exposure on marine protected areas: A global assessment.
Partelow, Stefan; von Wehrden, Henrik; Horn, Olga
2015-11-15
Marine protected areas (MPAs) face many challenges in their aim to effectively conserve marine ecosystems. In this study we analyze the extent of pollution exposure on the global fleet of MPAs. This includes indicators for current and future pollution and the implications for regionally clustered groups of MPAs with similar biophysical characteristics. To cluster MPAs into characteristic signature groups, their bathymetry, baseline biodiversity, distance from shore, mean sea surface temperature and mean sea surface salinity were used. We assess the extent at which each signature group is facing exposure from multiple pollution types. MPA groups experience similar pollution exposure on a regional level. We highlight how the challenges that MPAs face can be addressed through governance at the appropriate scale and design considerations for integrated terrestrial and marine management approaches within regional level networks. Furthermore, we present diagnostic social-ecological indicators for addressing the challenges facing unsuccessful MPAs with practical applications. Copyright © 2015 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Piman, T.; Vasconcelos, V. V.; Apirumanekul, C.; Krittasudthacheewa, C.
2017-12-01
Bank erosion along the braided stretches of Ayeyarwady and Chindwin Rivers has been one of the main concerns at Sagaing region, in Myanmar, because it threatens villages, infrastructure and farmland, while the consequent sedimentation hampers boat transportation. This study assesses the changes on these two river channels and its sandbanks, in their confluence area. A special focus is given to infer the risk of villages to bank erosion. Landsat images from 1973, 1989, and annual series from 1998 to 2015 were used to evaluate frequency and rates of erosion, deposition and vegetation restabilization. Maps showed where the channels maintained stable and which areas faced bank erosion more frequently. From 1973 to 2015, 30% of the river valley in the studied area faced bank erosion. Although the summed area of the river channel remained relatively stable throughout the period, the rates of bank erosion vs. bank restabilization were higher after 2004. Most of the village area in the in the river valley within the bluffs (89% - 71km2) have not faced bank erosion since 1973, while 8.9% (7 km2) are in vulnerable areas that faced erosion before 2012, and bank erosion destroyed 1.3% (1 km2) of the villages from 2012 to 2015. The average rate of village land loss from bank erosion within the river valley from 1973 to 2012 was 0.18 km2/year, but increased to 0.33km2/year during 2012-2015. The villages located just downstream from the confluence of Chindwin and Ayeyarwady River faced higher problems with bank erosion. Approximately half of the village area (51.5% - 87km2) adjacent to the bluffs (outside the river valley) were facing stable land since 1973 (lowest risk), while 5.8% (10 km2) were facing stable river channel (low risk) and 42.7% (73 km2) were facing areas of unstable river channel (possible risk). As for the biggest urban sites, Monywa and Pakokku face areas of unstable river channel, while Sagaing and Myingyan are safer, facing areas of stable land. A detailed assessment of remote sensing images also showed how Chindwin channel widened progressively due to bank erosion in the direction of Su Lay Kon and Ah Myning villages, in Monywa district. The rapid changes in river geomorphology calls for public's attention on alternative ways to live with these dynamic but important rivers.
Optomechanical design and testing of the VLT tertiary mirrors
NASA Astrophysics Data System (ADS)
Bollinger, Wolfgang; Juranek, Hans J.; Schulte, Stefan; May, K.; Michel, Alain
2000-07-01
The Tertiary Mirrors for the ESO Very Large Telescope project consist of four optical flats (elliptical, 890 X 1260 mm2). The achieved opto-mechanical design is challenging since it provides high optical overall quality combined with high stiffness (70 Hz Eigenfrequency) and low mass (total mass of 180 kg for the complete unit). Schott (Mainz, Germany) produces the lightweight Zerodur blanks. Carl Zeiss has designed and manufactured the mirror and its support cell. Last not least it became necessary to install the biggest testing equipment for flats in Europe to guarantee for a scientifically correct verification of the quality of the complete unit. All four mirrors have been delivered to ESO.
Materials design for new superconductors
Norman, M. R.
2016-05-23
Since the announcement in 2011 of the Materials Genome Initiative by the Obama administration, much attention has been given to the subject of materials design to accelerate the discovery of new materials that could have technological implications. Although having its biggest impact for more applied materials like batteries, there is increasing interest in applying these ideas to predict new superconductors. This is obviously a challenge, given that superconductivity is a many body phenomenon, with whole classes of known superconductors lacking a quantitative theory. Given this caveat, various efforts to formulate materials design principles for superconductors are reviewed in this paper,more » with a focus on surveying the periodic table in an attempt to identify cuprate analogues.« less
Ames Lab 101: 3D Metals Printer
Ott, Ryan
2018-01-16
To meet one of the biggest energy challenges of the 21st century - finding alternatives to rare-earth elements and other critical materials - scientists will need new and advanced tools. The Critical Materials Institute at the U.S. Department of Energy's Ames Laboratory has a new one: a 3D printer for metals research. 3D printing technology, which has captured the imagination of both industry and consumers, enables ideas to move quickly from the initial design phase to final form using materials including polymers, ceramics, paper and even food. But the Critical Materials Institute (CMI) will apply the advantages of the 3D printing process in a unique way: for materials discovery.
Recruiting as much about families as candidate
DOE Office of Scientific and Technical Information (OSTI.GOV)
Madison, Alison L.
2011-06-05
Monthly economic diversity column for Tri-City Herald: For businesses large and small, one of the biggest challenges to staying afloat and achieving growth is attracting and retaining key talent. And in an area such as the Tri-Cities, where many of our skilled professionals are geographical transplants and the technology-based economic growth we seek often requires highly specific skill sets, effective recruiting is especially critical. But it isn’t just about matching candidates with open positions and signing on the dotted line. In fact, members of the Three Rivers Entrepreneur Network were reminded at a recent presentation that recruiting is very muchmore » about attracting the family unit.« less