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Sample records for biodola elba italia

  1. Results from the Elba HF-2003 experiment

    NASA Astrophysics Data System (ADS)

    Jensen, Finn; Pautet, Lucie; Porter, Michael; Siderius, Martin; McDonald, Vincent; Badiey, Mohsen; Kilfoyle, Dan; Freitag, Lee

    2004-11-01

    In October of 2003, a high-frequency propagation and acoustic communications experiment was conducted off the Italian island of Elba. The experiment followed closely a previous experiment off Kauai (Hawaii Islands). In particular, a 5 km propagation path along the 100-m isobath was selected. Relative to the Kauai Experiment, the Elba test was significant both in terms of what was similar and what was different. The experiment geometry was identical and a similar mixed layer structure was expected. However, since NURC has worked extensively in this area in past tests we were able to confidently select two sites, one with a very soft bottom and one with a very hard bottom. The comparison between measurements at the two sites in Elba and in Kauai is very illuminating in terms of the propagation conditions and the performance of the acoustic communications scheme. A final significant change was the inclusion of multiple input/multiple output (i.e. using source/receive arrays) communications schemes. We summarize preliminary results from this experiment.

  2. 78 FR 25074 - Elba Liquefaction Company, L.L.C., Southern LNG Company, L.L.C., Elba Express Company, L.L.C...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ... Energy Regulatory Commission Elba Liquefaction Company, L.L.C., Southern LNG Company, L.L.C., Elba... Liquefaction Project, Request for Comments on Environmental Issues, and Notice of Public Scoping Meetings The... assessment (EA) that will discuss the environmental impacts of the Elba Liquefaction Project and EEC...

  3. 76 FR 71961 - Elba Express Company, L.L.C.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-21

    ... Energy Regulatory Commission Elba Express Company, L.L.C.; Notice of Application Take notice that on October 31, 2011, Elba Express Company, L.L.C. (EEC), 569 Brookwood Village, Suite 501, Birmingham... Affairs, Elba Express Company, L.L.C., 569 Brookwood Village, Suite 501, Birmingham, Alabama 35209,...

  4. SETI-Italia

    NASA Astrophysics Data System (ADS)

    Montebugnoli, Stelio; Monari, J.; Cattani, A.; Maccaferri, A.; Maccaferri, G.; Mariotti, S.; Poloni, M.; Scalambra, A.; D'Amico, M.; Maccone, C.; Cosmovici, C. B.

    2001-08-01

    During the last ten years, lots of exciting astronomical discoveries became possible because of advanced new technologies. SETI (Search for Extra Terrestrial Intelligence) is an international program led by the SETI Institute (located in Mountain View, California, USA) and is devoted to the search for an artificial monochromatic radio signal originated by an extraterrestrial civilisation. "SETI-Italia" is the official Italian contribution to the international SETI program. It begun in 1998, when a high-resolution SERENDIP IV spectrum analyser in a 4 million channels configuration was installed at the radio telescope in Medicina, near Bologna. Already in 1999 this system was upgraded to 24 million channels. Up to now (May 2001) observations have been carried out with the SERENDIP IV system connected in a piggyback mode to the 32 m VLBI (Very Long Baseline Interferometry) dish at the Medicina station. So far, Italy is the only European country joining the venture of SETI exploration together with the USA, Australia and Argentina.

  5. Two-stage growth of laccoliths at Elba Island, Italy

    NASA Astrophysics Data System (ADS)

    Rocchi, Sergio; Westerman, David S.; Dini, Andrea; Innocenti, Fabrizio; Tonarini, Sonia

    2002-11-01

    At Elba Island, Italy, nine shallow-level late Miocene granite porphyry layers connected by feeder dikes built up three nested Christmas-tree laccoliths. Detailed mapping and reconstruction of tectonic history led to restoration of the original 5-km-thick sequence and determination of the dimensional parameters of each intrusive layer. The laccolith layers were emplaced at depths between 1.9 and 3.7 km, exploiting physical discontinuities that served as crustal magma traps inside a stack of nappes. The intrusive layers are 50 700 m thick, with diameters between 1.6 and 10 km. Length to thickness relationships for individual laccolith layers show a power-law correlation that does not fit the known dimensional distribution for laccoliths, but instead fits a line with a slope typical of the theoretical vertical-inflation stage of laccolith development. This is interpreted as the first reported natural example of the occurrence of a vertical-inflation stage during laccolith growth. The dimensional data for Elba intrusive layers also suggest that laccoliths and plutons commonly form by amalgamation of smaller sheet-like bodies, while multilayer laccoliths form when coalescence fails, possibly owing to the large availability of crustal magma traps.

  6. Simulations of Flooding on Pea River and Whitewater Creek in the Vicinity of the Proposed Elba Bypass at Elba, Alabama

    USGS Publications Warehouse

    Hedgecock, T. Scott

    2003-01-01

    A two-dimensional finite-element surface-water model was used to study the effects of proposed modifications to the State Highway 203 corridor (proposed Elba Bypass/relocated U.S. Highway 84) on water-surface elevations and flow distributions during flooding in the Pea River and Whitewater Creek Basins at Elba, Coffee County, Alabama. Flooding was first simulated for the March 17, 1990, flood, using the 1990 flood-plain conditions to calibrate the model to match measured data collected by the U.S. Geological Survey and the U.S. Army Corps of Engineers after the flood. After model calibration, the effects of flooding were simulated for four scenarios: (1) floods having the 50- and 100-year recurrence intervals for the existing flood-plain, bridge, highway, and levee conditions; (2) floods having the 50- and 100-year recurrence intervals for the existing flood-plain and levee conditions with the State Highway 203 embankment and bridge removed; (3) floods having the 50- and 100-year recurrence intervals for the existing flood-plain, bridge, and highway conditions with proposed modifications (elevating) to the levee; and (4) floods having the 50- and 100-year recurrence intervals for the proposed conditions reflecting the Elba Bypass and modified levee. The simulation of floodflow for the Pea River and Whitewater Creek flood of March 17, 1990, in the study reach compared closely to flood profile data obtained after the flood. The flood of March 17, 1990, had an estimated peak discharge of 58,000 cubic feet per second at the gage (just below the confluence) and was estimated to be between a 50-year and 100-year flood event. The estimated peak discharge for Pea River and Whitewater Creek was 40,000 and 42,000 cubic feet per second, respectively. Simulation of floodflows for the 50-year flood (51,400 cubic feet per second) at the gage for existing flood-plain, bridge, highway, and levee conditions indicated that about 31 percent of the peak flow was conveyed by the State

  7. BEN domain protein Elba2 can functionally substitute for linker histone H1 in Drosophila in vivo

    PubMed Central

    Xu, Na; Lu, Xingwu; Kavi, Harsh; Emelyanov, Alexander V.; Bernardo, Travis J.; Vershilova, Elena; Skoultchi, Arthur I.; Fyodorov, Dmitry V.

    2016-01-01

    Metazoan linker histones are essential for development and play crucial roles in organization of chromatin, modification of epigenetic states and regulation of genetic activity. Vertebrates express multiple linker histone H1 isoforms, which may function redundantly. In contrast, H1 isoforms are not present in Dipterans, including D. melanogaster, except for an embryo-specific, distantly related dBigH1. Here we show that Drosophila BEN domain protein Elba2, which is expressed in early embryos and was hypothesized to have insulator-specific functions, can compensate for the loss of H1 in vivo. Although the Elba2 gene is not essential, its mutation causes a disruption of normal internucleosomal spacing of chromatin and reduced nuclear compaction in syncytial embryos. Elba2 protein is distributed ubiquitously in polytene chromosomes and strongly colocalizes with H1. In H1-depleted animals, ectopic expression of Elba2 rescues the increased lethality and ameliorates abnormalities of chromosome architecture and heterochromatin functions. We also demonstrate that ectopic expression of BigH1 similarly complements the deficiency of H1 protein. Thus, in organisms that do not express redundant H1 isoforms, the structural and biological functions performed by canonical linker histones in later development, may be shared in early embryos by weakly homologous proteins, such as BigH1, or even unrelated, non-homologous proteins, such as Elba2. PMID:27687115

  8. 77 FR 2970 - Notice of Intent To Prepare an Environmental Assessment for the Proposed Elba BOG Compressor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... Elba BOG Compressor Project and Request for Comments on Environmental Issues; Southern LNG Company, L.L... scoping process is to focus the analysis in the EA on the important environmental issues. By this notice... environmental issues of this project to formally cooperate with us in the preparation of the EA.\\3\\ Agencies...

  9. 77 FR 28864 - Elba Express Company, L.L.C.; Notice of Amendment to Petition To Amend Order Issuing Certificate

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ... amend their certificate issued in Docket No. CP06-471-000. Elba Express filed a Petition To Amend Order... authorization to change the location of the Phase B Compression from Jenkins County, Georgia to Elbert County, Georgia. As noticed herein, this amendment requests the Commission consider a site in Hart County,...

  10. HP-LT metamorphism in Elba Island: Implications for the geodynamic evolution of the inner Northern Apennines (Italy)

    NASA Astrophysics Data System (ADS)

    Bianco, Caterina; Brogi, Andrea; Caggianelli, Alfredo; Giorgetti, Giovanna; Liotta, Domenico; Meccheri, Marco

    2015-11-01

    The inner Northern Apennines belt (i.e., northern Tyrrhenian Sea and Tuscany) is an Alpine chain affected by high-P metamorphic conditions during its evolution. Although Elba Island is structurally located close to the Adria-Europe suture zone, for several authors it represents a sector of the orogen affected by low-P metamorphism. The involvement of Elba Island tectonic units in high-P metamorphism was only suspected for the sparse presence of phengitic white mica in the metasedimentary rocks. This paper presents the first clear evidence of high-P and low-T metamorphism found in metabasite rocks embedded in the Cretaceous calcschist of eastern Elba Island. Mineral composition of metabasite includes Gln + Cpx + Ep + Ab + Act + Qtz + Ilm ± Ti-oxide ± Spn and is indicative of a former equilibration in the epidote blueschist subfacies and subsequent retrogression in the greenschist facies. Recorded metamorphic conditions are P = 0.9-1.0 GPa and T = 330-350 °C. Tectonic discrimination using immobile elements in the metabasite does not point to an oceanic setting. As a consequence, the metasedimentary succession containing metabasite is explained as belonging to the Tuscan continental domain and not to the Ligurian-Piedmont Ocean, as previously interpreted. Our results have two significant implications: (i) it is confirmed and strengthened that the tectonic stacking of the Elba Island units did not occur in a low-pressure context; (ii) Elba Island is now completely reconciled in the tectonic and metamorphic evolution of the inner Northern Apennines.

  11. Variation in Herbage Biochemical Composition among Pitch Trefoil (Bituminaria bituminosa) Populations from Elba Island, Italy.

    PubMed

    Pecetti, Luciano; Mella, Mariella; Tava, Aldo

    2016-01-13

    This study assessed the variation in herbage protein and fiber content as well as concentration of furocoumarins, plicatin B, (E)-werneria chromene, and pterocarpans of pitch trefoil (Bituminaria bituminosa) germplasm sampled in situ in both summer and autumn in Elba Island, Italy. Populations were sampled from a range of climatic and edaphic conditions, on light soils with pH > 7.5. Valuable variation occurred for forage quality and chemical composition. The quality features, relevant for a possible forage utilization of the species, were promising for the leaves, which represented about two-thirds of the total aerial biomass in early summer and the whole green regrowth in autumn. The species can also represent a source of psoralen, angelicin, plicatin B, bitucarpin A, and erybraedin C for possible pharmaceutical and/or agrochemical use, with individual populations showing high levels of these compounds.

  12. Sericitic alteration at the La Crocetta deposit (Elba Island, Italy): interplay between magmatism, tectonics and hydrothermal activity

    NASA Astrophysics Data System (ADS)

    Maineri, Cinzia; Benvenuti, Marco; Costagliola, Pilar; Dini, Andrea; Lattanzi, Pierfranco; Ruggieri, Giovanni; Villa, Igor M.

    2003-01-01

    The La Crocetta mine near Porto Azzurro (Elba Island, Tuscany, Italy) is an important producer of raw material for the ceramic industry. Exploitation focuses on a pervasively sericitized porphyritic aplite of the Tuscan Magmatic Province, locally known as "eurite", which underwent significant potassium enrichment during sericitic alteration. Eurites are located along the hanging wall of the Elba Centrale Fault, a low-angle extensional lineament of regional significance. A later carbonatization stage, apparently associated with high-angle extensional tectonics, locally overprinted the sericitized facies. It is expressed by carbonate ± pyrite ± quartz veins, with adverse effects on ore quality. Sericitization was accompanied by addition of potassium, and loss of Na (± Ca, Fe). Rubidium was not enriched along with potassium during sericitization, contrary to what would be expected for interaction with late-magmatic fluids. New 40Ar-39Ar data from eurites provide an isochron age of about 6.7 Ma for the sericitization, whereas the age of the unaltered protolith is ca. 8.8 Ma. Field evidence indicates the Elba Centrale Fault to be the main channel for the hydrothermal fluids. On the other hand, the involvement of heat and/or fluids contributed by the Porto Azzurro pluton, which crops out in the La Crocetta area, is ruled out by field, geochemical and geochronological data (40Ar-39Ar age of Porto Azzurro =5.9 Ma, i.e. significantly younger than the sericitization event). Fluid inclusion studies suggest that sericitization was associated with a low-temperature (<250 °C) hydrothermal system. Fluids were locally boiling, of variable salinity (4-17 wt% NaCl equiv.), and contained some CO2 ( XCO2≤0.027). Their ultimate source is not unequivocally constrained; meteoric and/or magmatic contributions may be possible. Low-salinity (≤2.6 wt% NaCl equiv.), low-temperature (<250 °C) fluids are associated with the late carbonate veining. They are considered to be of

  13. The Cotoncello Shear Zone (Elba Island, Italy): The deep root of a fossil oceanic detachment fault in the Ligurian ophiolites

    NASA Astrophysics Data System (ADS)

    Frassi, Chiara; Musumeci, Giovanni; Zucali, Michele; Mazzarini, Francesco; Rebay, Gisella; Langone, Antonio

    2017-05-01

    The ophiolite sequences in the western Elba Island are classically interpreted as a well-exposed ocean-floor section emplaced during the Apennines orogeny at the top of the tectonic nappe-stack. Stratigraphic, petrological and geochemical features indicate that these ophiolite sequences are remnants of slow-ultraslow spreading oceanic lithosphere analogous to the present-day Mid-Atlantic Ridge and Southwest Indian Ridge. Within the oceanward section of Tethyan lithosphere exposed in the Elba Island, we investigated for the first time a ​10s of meters-thick structure, the Cotoncello Shear Zone (CSZ), that records high-temperature ductile deformation. We used a multidisciplinary approach to document the tectono-metamorphic evolution of the shear zone and its role during spreading of the western Tethys. In addition, we used zircon U-Pb ages to date formation of the gabbroic lower crust in this sector of the Apennines. Our results indicate that the CSZ rooted below the brittle-ductile transition at temperature above 800 °C. A high-temperature ductile fabric was overprinted by fabrics recorded during progressive exhumation up to shallower levers under temperature < 500 °C. We suggest that the CSZ may represent the deep root of a detachment fault that accomplished exhumation of an ancient oceanic core complex (OCC) in between two stages of magmatic accretion. We suggest that the CSZ represents an excellent on-land example enabling to assess relationships between magmatism and deformation when extensional oceanic detachments are at work.

  14. A Review on Prediction Methods for Molar Enthalpies of Vaporization of Hydrocarbons: The ELBA Method as the Best Answer

    NASA Astrophysics Data System (ADS)

    Santos, Rui C.; Leal, João P.

    2012-12-01

    A review on prediction methods for molar enthalpies of vaporization at T = 298.15 K of hydrocarbons is presented. A new method is proposed and compared with six of the most common used ones from the literature. This new method, the extended Laidler bond additivity (ELBA), was applied to the prediction of standard molar enthalpies of vaporization of hydrocarbons (alkanes, alkenes, alkynes, polyenes, poly-ynes, cycloalkanes, cycloalkenes, benzene compounds, biphenyl compounds, and polyphenyl compounds) at T = 298.15 K. A total of 260 experimental standard molar enthalpies of vaporization at T = 298.15 K were used for the parameters optimization. Comparison between the experimental values and those calculated using ELBA led to an average absolute difference of 0.35 kJ mol-1, corresponding to an average relative error of 0.92%. In addition, this new method proves to be better than the ones used for comparison with an independent set of 83 experimental standard molar enthalpies of vaporization at T = 298.15 K.

  15. World average top-quark mass

    SciTech Connect

    Glenzinski, D.; /Fermilab

    2008-01-01

    This paper summarizes a talk given at the Top2008 Workshop at La Biodola, Isola d Elba, Italy. The status of the world average top-quark mass is discussed. Some comments about the challanges facing the experiments in order to further improve the precision are offered.

  16. Petrological and tectono-magmatic significance of ophiolitic basalts from the Elba Island within the Alpine Corsica-Northern Apennine system

    NASA Astrophysics Data System (ADS)

    Saccani, Emilio; Principi, G.

    2016-12-01

    Two distinct ophiolitic units, which represent remnants of the Jurassic Ligurian-Piedmont Ocean, crop out in the Elba Island. They are the Monte Strega unit in central-eastern Elba and the Punta Polveraia-Fetovaia unit in western Elba. Ophiolitic rocks from the Monte Strega unit are commonly affected by ocean floor metamorphism, whereas those from the Punta Polveraia-Fetovaia unit are affected to various extent by thermal metamorphism associated with the Late Miocene Monte Capanne monzogranitic intrusion. Both ophiolitic units include pillow lavas and dykes with compositions ranging from basalt to basaltic andesite, Fe-basalt, and Fe-basaltic andesite. Basaltic rocks from these distinct ophiolitic units show no chemical differences, apart those due to fractional crystallization processes. They display a clear tholeiitic nature with low Nb/Y ratios and relatively high TiO2, P2O5, Zr, and Y contents. They generally display flat N-MORB normalized high field strength element patterns, which are similar to those of N-MORB. Chondrite-normalized rare earth element patterns show light REE / middle REE (LREE/MREE) depletion and marked heavy (H-) REE fractionation with respect to MREE. This HREE/MREE depletion indicates a garnet signature of their mantle sources. Accordingly, they can be classified as garnet-influenced MORB (G-MORB), based on Th, Nb, Ce, Dy, and Yb systematics. We suggest that the Elba Island ophiolitic basalts were generated at a magma starved, slow-spreading mid-ocean ridge. REE, Th, and Nb partial melting modelling shows that the compositions of the relatively primitive Elba Island ophiolitic basalts are compatible with partial melting of a depleted MORB mantle (DMM) source bearing garnet-pyroxenite relics. Hygromagmatophile element ratios suggest that basalts from both ophiolitic units were originated from chemically very similar mantle sources. A comparison with basalts and metabasalts from Alpine Corsica and northern Apennine ophiolitic units shows

  17. Human fatigue and the crash of the airship Italia

    PubMed Central

    Bendrick, Gregg A.; Beckett, Scott A.; Klerman, Elizabeth B.

    2016-01-01

    The airship Italia, commanded by General Umberto Nobile, crashed during its return flight from the North Pole in 1928. The cause of the accident was never satisfactorily explained. We present evidence that the crash may have been fatigue-related. Nobile’s memoirs indicate that at the time of the crash he had been awake for at least 72 h. Sleep deprivation impairs multiple aspects of cognitive functioning necessary for exploration missions. Just prior to the crash, Nobile made three command errors, all of which are of types associated with inadequate sleep. First, he ordered a release of lift gas when he should have restarted engines (an example of incorrect data synthesis, with deterioration of divergent thinking); second, he inappropriately ordered the ship above the cloud layer (a deficiency in the assessment of relative risks); and third, he remained above the cloud layer for a prolonged period of time (examples of attention to secondary problems, and calculation problems). We argue that as a result of these three errors, which would not be expected from such an experienced commander, there was no longer enough static lift to maintain level flight when the ship went below the cloud layer. Applying Circadian Performance Simulation Software to the sleep–wake patterns described by Nobile in his memoirs, we found that the predicted performance for someone awake as long as he had been is extremely low. This supports the historical evidence that human fatigue contributed to the crash of the Italia. PMID:28490834

  18. Human fatigue and the crash of the airship Italia.

    PubMed

    Bendrick, Gregg A; Beckett, Scott A; Klerman, Elizabeth B

    2016-01-01

    The airship Italia, commanded by General Umberto Nobile, crashed during its return flight from the North Pole in 1928. The cause of the accident was never satisfactorily explained. We present evidence that the crash may have been fatigue-related. Nobile's memoirs indicate that at the time of the crash he had been awake for at least 72 h. Sleep deprivation impairs multiple aspects of cognitive functioning necessary for exploration missions. Just prior to the crash, Nobile made three command errors, all of which are of types associated with inadequate sleep. First, he ordered a release of lift gas when he should have restarted engines (an example of incorrect data synthesis, with deterioration of divergent thinking); second, he inappropriately ordered the ship above the cloud layer (a deficiency in the assessment of relative risks); and third, he remained above the cloud layer for a prolonged period of time (examples of attention to secondary problems, and calculation problems). We argue that as a result of these three errors, which would not be expected from such an experienced commander, there was no longer enough static lift to maintain level flight when the ship went below the cloud layer. Applying Circadian Performance Simulation Software to the sleep-wake patterns described by Nobile in his memoirs, we found that the predicted performance for someone awake as long as he had been is extremely low. This supports the historical evidence that human fatigue contributed to the crash of the Italia.

  19. Hydrogeochemical considerations about the origin of groundwater salinization in some coastal plains of Elba Island (Tuscany, Italy).

    PubMed

    Giménez-Forcada, Elena; Bencini, Alberto; Pranzini, Giovanni

    2010-06-01

    Several coastal plains of the Elba Island (Marina di Campo, Portoferraio, Schiopparello, Mola, Porto Azzurro and Barbarossa plains) in Tuscany (Italy) were studied to determine the causes of decline in groundwater quality, using major ion chemistry to establish the causes of groundwater salinization. The study demonstrates that salinization of coastal plain alluvial aquifers is not simply linked to seawater intrusion but is also intimately related to inflows from adjacent aquifers. Ionic ratios, correlation graphs and distribution value maps were employed as the means to understand the hydrochemistry of the study areas. The Mg/Cl ratio in particular can be considered a good tracer to distinguish the main salinization processes that control groundwater chemistry. Seawater intrusion only partly determines the chemistry of some groundwaters, which generally belong to a chloride facies where the salinity is derived principally from freshwater-seawater mixing and the participation of cation exchange. Proceeding inland groundwater quality seems to be principally determined by the inflow of Mg, Ca-HCO(3) or Ca, Na-HCO(3) waters formed from the weathering of silicate minerals in adjoining aquifers. Hydrolysis of these minerals is of prime importance in controlling groundwater chemistry in adjacent alluvial plains. The lateral recharge flows introduce water with a different chemical composition and this variable of freshwater recharge changes the hydrochemistry as a result of mixing between two or more waters types. This situation is further complicated when seawater and base exchange reactions participate, due to seawater intrusion.

  20. Tourmaline nodules from Capo Bianco aplite (Elba Island, Italy): an example of diffusion limited aggregation growth in a magmatic system

    NASA Astrophysics Data System (ADS)

    Perugini, Diego; Poli, Giampiero

    2007-05-01

    The morphology of tourmaline nodules occurring in the Capo Bianco aplite (Elba Island, Italy) is studied. Outcrop features indicate that tourmaline nodules are the product of magmatic crystallization, as they are aligned along flow fields developed within the magmatic hosting mass. Mesoscopic observations indicate that nodule morphologies are very variable, from rounded to dendritic. Morphometric analyses show that tourmaline nodules are fractals and that fractal dimension quantifies their degree of irregularity. Numerical simulations of nodule growth are performed by using a Diffusion-Limited Aggregation process. The presence in natural samples of nodules with different morphologies is explained by considering a chaotic magmatic system characterized by a complex interplay between growth rate in different dynamical regions, latent heat of crystallization, and local convection dynamics. It is suggested that higher growth rates correspond to growth of tourmaline nodules in dynamical regions where the transfer of nutrients is very efficient. In such conditions, the latent heat released by the growing nodule is high, inducing strong local convection dynamics, destabilizing the nodule interface, and promoting the formation of dendritic morphologies. On the contrary, the growth of nodules in dynamical regions characterized by weak transfer of nutrients is inhibited leading to weak local convection dynamics and, consequently, to the formation of rounded morphologies.

  1. Drought impact on water use efficiency and intra-annual density fluctuations in Erica arborea on Elba (Italy).

    PubMed

    Battipaglia, Giovanna; DE Micco, Veronica; Brand, Willi A; Saurer, Matthias; Aronne, Giovanna; Linke, Petra; Cherubini, Paolo

    2014-02-01

    Erica arborea (L) is a widespread Mediterranean species, able to cope with water stress and colonize semiarid environments. The eco-physiological plasticity of this species was evaluated by studying plants growing at two sites with different soil moistures on the island of Elba (Italy), through dendrochronological, wood-anatomical analyses and stable isotopes measurements. Intra-annual density fluctuations (IADFs) were abundant in tree rings, and were identified as the key parameter to understand site-specific plant responses to water stress. Our findings showed that the formation of IADFs is mainly related to the high temperature, precipitation patterns and probably to soil water availability, which differs at the selected study sites. The recorded increase in the (13) C-derived intrinsic water use efficiency at the IADFs level was linked to reduced water loss rather than to increasing C assimilation. The variation in vessel size and the different absolute values of δ(18) O among trees growing at the two study sites underlined possible differences in stomatal control of water loss and possible differences in sources of water uptake. This approach not only helped monitor seasonal environmental differences through tree-ring width, but also added valuable information on E. arborea responses to drought and their ecological implications for Mediterranean vegetation dynamics. © 2013 John Wiley & Sons Ltd.

  2. Underwater acoustic positioning system for the SMO and KM3NeT - Italia projects

    SciTech Connect

    Viola, S.; Barbagallo, G.; Cacopardo, G.; Calí, C.; Cocimano, R.; Coniglione, R.; Costa, M.; Cuttone, G.; D'Amato, C.; D'Amato, V.; D'Amico, A.; De Luca, V.; Del Tevere, F.; Distefano, C.; Ferrera, F.; Gmerk, A.; Grasso, R.; Imbesi, M.; Larosa, G.; Lattuada, D.; and others

    2014-11-18

    In the underwater neutrino telescopes, the positions of the Cherenkov light sensors and their movements must be known with an accuracy of few tens of centimetres. In this work, the activities of the SMO and KM3NeT-Italia teams for the development of an acoustic positioning system for KM3NeT-Italia project are presented. The KM3NeT-Italia project foresees the construction, within two years, of 8 towers in the view of the several km{sup 3}-scale neutrino telescope KM3NeT.

  3. The Upper Miocene magmatism of the Island of Elba (Central Italy): compositional characteristics, petrogenesis and implications for the origin of the Tuscany Magmatic Province

    NASA Astrophysics Data System (ADS)

    Poli, Giampiero; Peccerillo, Angelo

    2016-08-01

    Late Miocene intrusive magmatism of the Island of Elba, Tuscany (central Italy), consists of stocks, laccoliths, sills, and dikes showing dominant monzogranite and granodiorite compositions, with minor leucogranitic dike-sill complexes, aplites and pegmatites. A few mafic rocks occur as dikes, and as microgranular enclaves hosted inside the main intrusions. The Elba magmatism belongs to the Tuscan Magmatic Province, an 8.5 to 0.3 Ma old association of mafic to felsic rocks, of mantle and crustal origin, cropping out in Tuscany and northern Latium. Major and trace element abundances of Elba rocks are extremely variable, testifying to complex origin and evolutionary history for magmas. 87Sr/86Sr (~ 0.708-0.723) and 143Nd/144Nd (~0.5121-0.5124) are close or within the field of upper continental crust, with mafic dikes showing the lowest Sr- and the highest Nd-isotope ratios. Petrological, geochemical and textural data of Elba igneous rocks are better explained by invoking a leading role for multiple mixing processes between crust-derived felsic magmas and mafic-intermediate melts of ultimate mantle origin, accompanied by fractional crystallisation. Proxies of crustal anatectic melts are represented by some highly radiogenic-Sr rocks from northern Monte Capanne pluton. Crustal magmas were formed by melting of sedimentary rocks, likely metagreywakes, at pressures exceeding 0.3 GPa. Mafic-intermediate magmas have calcalkaline to shoshonitic compositions and originated in an anomalous mantle, moderately contaminated by siliceous sediments. Selective enrichments in Sr, Ba and LREE are shown by some intermediate rocks (Orano dikes), revealing the occurrence of a distinct magma type at Elba. Similar compositions are also observed at Capraia island, San Vincenzo and Campiglia (southern Tuscany), suggesting a regional relevance for this magma type. Sr-Ba-LREE-rich rocks do not show obvious genetic relationships with other Tuscany magmas and may represent a distinct end

  4. From Gondwana to Europe: the journey of Elba Island (Italy) as recorded by U-Pb detrital zircon ages of Paleozoic metasedimentary rocks

    NASA Astrophysics Data System (ADS)

    Jacobs, Joachim; Sirevaag, Hallgeir; Ksienzyk, Anna K.; Rocchi, Sergio; Paoli, Gabriele

    2016-04-01

    The configuration of the northern Gondwana margin throughout the Paleozoic is difficult to reconstruct owing to the complex geodynamic setting of the Mediterranean region in Mesozoic to Cenozoic times. Detrital zircons in early Paleozoic to early Mesozoic metasedimentary rocks on Elba and mainland Tuscany record the Gondwana provenance of Adria and its rifting from the northern Gondwana margin. A large new LA-ICP-MS and SIMS U-Pb zircon data set allows us to trace this history. Three main stratigraphic units have been investigated on Elba Island. The oldest Porto Azzurro Unit was deposited in the early Cambrian and has zircon age distributions indicating a typical northern African provenance, most likely sourced from the Saharan Metacraton. The Ortano Unit has a simple, mostly unimodal Ordovician age distribution that is entirely dominated by metavolcanic rocks and their erosional products; a sample of the metavolcanic Ortano Porphyroids provided a SIMS U-Pb zircon age of 460 ± 3 Ma. This phase of intense volcanism is related to the subduction of the Rheic Ocean beneath Gondwana, terminating with initial rifting and subsequent opening of the Paleotethys. This also marks the onset of the separation of a range of European terranes, including Adria and future Elba Island, from Gondwana. The Permo-Triassic Monticiano-Roccastrada Unit is the first to show a European provenance with the appearance of large amounts of Variscan and late to post-Variscan detritus. The presence of Variscan detrital zircons in the Permo-Triassic sediments is unexpected, since a Variscan age signature is so far not well recorded in the Adria Plate. This dataset is the most comprehensive detrital zircon data set so far available for the Adria Plate and documents Adria's close affinity to Africa in the Lower Paleozoic, as well as its initial rifting within an active continental margin setting during the Ordovician and its final separation and independent evolution since late Palaeozoic times.

  5. [Health for All-Italia: an indicator system on health].

    PubMed

    Burgio, Alessandra; Crialesi, Roberta; Loghi, Marzia

    2003-01-01

    The Health for All - Italia information system collects health data from several sources. It is intended to be a cornerstone for the achievement of an overview about health in Italy. Health is analyzed at different levels, ranging from health services, health needs, lifestyles, demographic, social, economic and environmental contexts. The database associated software allows to pin down statistical data into graphs and tables, and to carry out simple statistical analysis. It is therefore possible to view the indicators' time series, make simple projections and compare the various indicators over the years for each territorial unit. This is possible by means of tables, graphs (histograms, line graphs, frequencies, linear regression with calculation of correlation coefficients, etc) and maps. These charts can be exported to other programs (i.e. Word, Excel, Power Point), or they can be directly printed in color or black and white.

  6. Response of spontaneous plants from an ex-mining site of Elba island (Tuscany, Italy) to metal(loid) contamination.

    PubMed

    Pistelli, Laura; D'Angiolillo, Francesca; Morelli, Elisabetta; Basso, Barbara; Rosellini, Irene; Posarelli, Mauro; Barbafieri, Meri

    2017-01-27

    The release of large amounts of toxic metals in the neighboring sites of abandoned mine areas represents an important environmental risk for the ecosystem, because it adversely affects soil, water, and plant growth. The aim of the present study was to investigate the metal(loid) (As, Cr, Cu, Ni, Pb, and Zn) contents of native Mediterranean plants grown on the ex-mining area of Elba island (Italy), with the prospective of its recovery by further phytoremediation technology. Soil samples were collected and characterized for metal(loid) content in total and potentially available (EDTA-extractable) fractions. Arsenic was particularly high, being 338 and 2.1 mg kg(-1) as total and available fractions, respectively. Predominant native species, namely Dittrichia viscosa L. Greuter, Cistus salviifolius L., Lavandula stoechas L., and Bituminaria bituminosa L., were analyzed for metal content in the different plant organs. D. viscosa exhibited the highest metal(loid) content in the leaves and the singular behavior of translocating arsenic to the leaves (transfer factor about 2.06 and mean bioconcentration factor about 12.48). To assess the healthy status of D. viscosa plants, the leaves were investigated further. The activities of the main antioxidant enzymes and the levels of secondary metabolites linked to oxidative stress in plants from the ex-mining area were not significantly different from those of control plants, except for a lower content of carotenoids, indicating that native plants were adapted to grow in these polluted soils. These results indicate that D. viscosa can be suitable for the revegetation of highly metal-contaminated areas.

  7. An overview of molecular dynamics simulations of oxidized lipid systems, with a comparison of ELBA and MARTINI force fields for coarse grained lipid simulations.

    PubMed

    Siani, P; de Souza, R M; Dias, L G; Itri, R; Khandelia, H

    2016-10-01

    Biological membranes and model lipid systems containing high amounts of unsaturated lipids and sterols are subject to chemical and/or photo-induced lipid oxidation, which leads to the creation of exotic oxidized lipid products (OxPLs). OxPLs are known to have significant physiological impact in cellular systems and also affect physical properties of both biological and model lipid bilayers. In this paper we (i) provide a perspective on the existing literature on simulations of lipid bilayer systems containing oxidized lipid species as well as the main related experimental results, (ii) describe our new data of all-atom and coarse-grained simulations of hydroperoxidized lipid monolayer and bilayer systems and (iii) provide a comparison of the MARTINI and ELBA coarse grained force fields for lipid bilayer systems. We show that the better electrostatic treatment of interactions in ELBA is able to resolve previous conflicts between experiments and simulations. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Róg. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Methane Seep in Shallow-Water Permeable Sediment Harbors High Diversity of Anaerobic Methanotrophic Communities, Elba, Italy

    PubMed Central

    Ruff, S. Emil; Kuhfuss, Hanna; Wegener, Gunter; Lott, Christian; Ramette, Alban; Wiedling, Johanna; Knittel, Katrin; Weber, Miriam

    2016-01-01

    The anaerobic oxidation of methane (AOM) is a key biogeochemical process regulating methane emission from marine sediments into the hydrosphere. AOM is largely mediated by consortia of anaerobic methanotrophic archaea (ANME) and sulfate-reducing bacteria (SRB), and has mainly been investigated in deep-sea sediments. Here we studied methane seepage at four spots located at 12 m water depth in coastal, organic carbon depleted permeable sands off the Island of Elba (Italy). We combined biogeochemical measurements, sequencing-based community analyses and in situ hybridization to investigate the microbial communities of this environment. Increased alkalinity, formation of free sulfide and nearly stoichiometric methane oxidation and sulfate reduction rates up to 200 nmol g-1 day-1 indicated the predominance of sulfate-coupled AOM. With up to 40 cm thickness the zones of AOM activity were unusually large and occurred in deeper sediment horizons (20–50 cm below seafloor) as compared to diffusion-dominated deep-sea seeps, which is likely caused by advective flow of pore water due to the shallow water depth and permeability of the sands. Hydrodynamic forces also may be responsible for the substantial phylogenetic and unprecedented morphological diversity of AOM consortia inhabiting these sands, including the clades ANME-1a/b, ANME-2a/b/c, ANME-3, and their partner bacteria SEEP-SRB1a and SEEP-SRB2. High microbial dispersal, the availability of diverse energy sources and high habitat heterogeneity might explain that the emission spots shared few microbial taxa, despite their physical proximity. Although the biogeochemistry of this shallow methane seep was very different to that of deep-sea seeps, their key functional taxa were very closely related, which supports the global dispersal of key taxa and underlines strong selection by methane as the predominant energy source. Mesophilic, methane-fueled ecosystems in shallow-water permeable sediments may comprise distinct

  9. Methane Seep in Shallow-Water Permeable Sediment Harbors High Diversity of Anaerobic Methanotrophic Communities, Elba, Italy.

    PubMed

    Ruff, S Emil; Kuhfuss, Hanna; Wegener, Gunter; Lott, Christian; Ramette, Alban; Wiedling, Johanna; Knittel, Katrin; Weber, Miriam

    2016-01-01

    The anaerobic oxidation of methane (AOM) is a key biogeochemical process regulating methane emission from marine sediments into the hydrosphere. AOM is largely mediated by consortia of anaerobic methanotrophic archaea (ANME) and sulfate-reducing bacteria (SRB), and has mainly been investigated in deep-sea sediments. Here we studied methane seepage at four spots located at 12 m water depth in coastal, organic carbon depleted permeable sands off the Island of Elba (Italy). We combined biogeochemical measurements, sequencing-based community analyses and in situ hybridization to investigate the microbial communities of this environment. Increased alkalinity, formation of free sulfide and nearly stoichiometric methane oxidation and sulfate reduction rates up to 200 nmol g(-1) day(-1) indicated the predominance of sulfate-coupled AOM. With up to 40 cm thickness the zones of AOM activity were unusually large and occurred in deeper sediment horizons (20-50 cm below seafloor) as compared to diffusion-dominated deep-sea seeps, which is likely caused by advective flow of pore water due to the shallow water depth and permeability of the sands. Hydrodynamic forces also may be responsible for the substantial phylogenetic and unprecedented morphological diversity of AOM consortia inhabiting these sands, including the clades ANME-1a/b, ANME-2a/b/c, ANME-3, and their partner bacteria SEEP-SRB1a and SEEP-SRB2. High microbial dispersal, the availability of diverse energy sources and high habitat heterogeneity might explain that the emission spots shared few microbial taxa, despite their physical proximity. Although the biogeochemistry of this shallow methane seep was very different to that of deep-sea seeps, their key functional taxa were very closely related, which supports the global dispersal of key taxa and underlines strong selection by methane as the predominant energy source. Mesophilic, methane-fueled ecosystems in shallow-water permeable sediments may comprise distinct

  10. Pyrimethanil residues on table grapes Italia after field treatment.

    PubMed

    Angioni, Alberto; Sarais, Giorgia; Dedola, Fabrizio; Caboni, Pierluigi

    2006-01-01

    Residues of the pyrimidine fungicide pyrimethanil [N-(4,6-dimethylpyrimidin-2yl)aniline] were determined in table grapes "Italia" by gas chromatography nitrogen-phosphorus detector (GC-NPD). Pesticides were extracted from grapes with ethyl acetate and hexane solution (1:1 v/v), and were analyzed without any further clean up. Pyrimethanil was confirmed by high-performance liquid chromatography (HPLC) fitted with a diode array detector (DAD) and electrospray ionization mass spectrometry (ESI-MS) in the select ion-monitoring mode (SIM). The residue of pyrimethanil was under the legal limit immediately after treatment, and showed a half-life time, calculated as a reaction of pseudo first order, of 12 days, with a regression coefficient of 0.9954. Recoveries from fortified grapes ranged between 90 and 113% with a maximum coefficient of variation (CV) of 11%. The calculated limits of detection and quantitation for pyrimethanil were 0.005 and 0.01 mg/kg, respectively.

  11. Coexistence of low-angle normal and high-angle strike- to oblique-slip faults during Late Miocene mineralization in eastern Elba Island (Italy)

    NASA Astrophysics Data System (ADS)

    Liotta, Domenico; Brogi, Andrea; Meccheri, Marco; Dini, Andrea; Bianco, Caterina; Ruggieri, Giovanni

    2015-10-01

    In this paper we deal with the kinematic and chronological relationships among low angle normal faults and high angle strike- to oblique-slip faults in an exhumed mineralized area, where shear veins and minor associated structures filled with the same mineral assemblage has been interpreted as indicators of coeval fault activities. The study area is located in the eastern Elba Island, where a mineralized late Miocene-early Pliocene low-angle normal fault (Zuccale fault) and high-angle strike- to oblique-slip faults extensively crop out, the latter giving rise to the Capoliveri-Porto Azzurro shear zone. The field study highlighted that: (a) the damage zones of both fault sets are mineralized by syn-kinematic tourmaline, graphite, Fe-oxides and/or Fe-oxyhydroxides shear veins, thus indicating their coeval activity during the hydrothermal event (5.9-5.4 Ma); (b) the Capoliveri-Porto Azzurro shear zone is constituted by a network of fractures, whose geometry and kinematics display the evolution of a NE-trending left-lateral oblique-slip transtensional shear zone; (c) its internal architecture is defined by tourmaline and Fe-oxides and/or Fe-oxyhydroxides mineralized veins, framed in the same kinematic field characterizing the Zuccale fault evolution; for this reason, the Capoliveri-Porto Azzurro shear zone is interpreted as a transfer zone active during the low-angle fault activity; (d) the Capoliveri-Porto Azzurro shear zone played the role of a significant normal fault during the Late Pliocene-Pleistocene, therefore favouring the deepening of the Tyrrhenian Basin with respect to the uplift and exhumation of the mid-crustal rocks of the Elba Island. It is finally argued that the interaction between the low-angle normal fault and the almost vertical shear zone determined an increase of permeability, favouring the mineralizing fluid flow during the hydrothermal stage and, reasonably, the previous emplacement of the Porto Azzurro magmatic body.

  12. The island of Elba (Tuscany, Italy) at the crossroads of ancient trade routes: an archaeometric investigation of dolia defossa from the archaeological site of San Giovanni

    NASA Astrophysics Data System (ADS)

    Manca, Rosarosa; Pagliantini, Laura; Pecchioni, Elena; Santo, Alba P.; Cambi, Franco; Chiarantini, Laura; Corretti, Alessandro; Costagliola, Pilario; Orlando, Andrea; Benvenuti, Marco

    2016-12-01

    Dolia are large pottery containers used in Roman times for the storage and fermentation of wine. They were produced in specialized pottery workshops ( figlinae) and were typically marked with specific epigraphical stamps, which represent a major tool to unravel their provenance and trade. In this work we present the preliminary results of a study of two dolia defossa, recently found at San Giovanni (Portoferraio, island of Elba, Italy) during 2012-2014 archaeological excavations in a Roman farm (late 2nd cent. BC-1st cent. AD), devoted to wine production and probably constituting the antecedent archaeological phase of the adjacent "Villa delle Grotte". Based on archaeological (epigraphic) evidence, five different production areas have been hypothesized: 1) Elba island, where the dolia have been found; 2) the municipal figlinae in the Pisa territory; 3) the middle catchment of the Tiber river (central Latium) where "urban" figlinae occurred; 4) the figlinae of Minturno (southern Latium), a locality known both for wine production and exportation and for the presence of ancient figlinae; 5) the municipal figlinae in the Volterra territory. Archaeometric analysis of tempering agents intentionally added to the clay for the manufacturing of the dolia, particularly magmatic lithic fragments and clinopyroxene crystals, allowed us to suggest that the watershed of the central Tiber Valley - including different volcanic centres belonging to both Tuscany Magmatic Province (Monti Cimini) and Roman Magmatic Province (Monti Vulsini and Vico volcano) - could have been the most likely sites of production of the dolia found at San Giovanni. Alternatively, the site of Minturno (southern Latium) could be proposed.

  13. Design and mass production of the optical modules for KM3NeT-Italia project

    NASA Astrophysics Data System (ADS)

    Leonora, Emanuele; Aiello, Sebastiano; Giordano, Valentina

    2016-04-01

    The KM3NeT European project aims at constructing a km3 underwater neutrino telescope in the depths of the Mediterranean Sea. The first phase that is under construction will comprise eight tower-like detection structures (KM3NeT-Italia), which will form the internal core of a km3-scale detector. The detection element of KM3NeT-Italia, the optical module, is made of a 13-inch pressure-resistant glass-vessel that contains a single 10-inch photomultiplier and the relative electronics. The design of the whole optical module, the main results obtained from the massive photomultipliers measurements, and the foremost phases of the mass production procedure performed at the production site of Catania are also presented.

  14. Photometry of asteroids 133 Cyrene, 454 Mathesis, 477 Italia, and 2264 Sabrina

    NASA Astrophysics Data System (ADS)

    Buchheim, Robert K.

    2006-06-01

    Photometric studies of asteroids 133 Cyrene, 454 Mathesis, 477 Italia and 2264 Sabrina are reported. The lightcurve period for Cyrene of 12.707±0.015 h (with amplitude 0.22 mag) confirms prior studies. The lightcurve period of 8.37784±0.00003 h (amplitude 0.32 mag) for Mathesis differs from previous studies. For Italia, color indices (B-V)=0.87±0.07, (V-R)=0.48±0.05, and phase curve parameters H=10.4, G=0.15 have been determined. For Sabrina, this study provides the first reported lightcurve period 43.41±0.02 h, with 0.30 mag amplitude.

  15. Archaeobotanical reconstructions of vegetation and report of mummified apple seeds found in the cellar of a first-century Roman villa on Elba Island.

    PubMed

    Milanesi, Claudio; Scali, Monica; Vignani, Rita; Cambi, Franco; Dugerdil, Lucas; Faleri, Claudia; Cresti, Mauro

    In the late Roman Republic period (2nd-1st century BC), in the area of San Giovanni on Elba Island, previously subject to intense extraction of iron ore, a rustic villa was established by Marco Valerio Messalla, a supreme Roman magistrate. The foundations of the walls were discovered and excavated by an archaeological mission. Palaeobotanical analysis of a set of stratigraphic layers was performed. Palynological slides showed remains of palynomorphic and non-pollen objects, while data combined with anthracological investigations confirmed the hypothesis that in the 1st century AD the villa was destroyed by a fire that created a compact crust under which were discovered four broken Roman amphorae containing about five hundred apple seeds. Comparisons of archaeological and fresh seeds from reference collections showed discontinuous morphology except for one group of archaeological samples. DNA was isolated from seeds that had well-preserved embryos in all groups. DNA extracts from archaeological, wild and modern domestic seeds (controls) were amplified by PCR and tested with SSR molecular markers, followed by genome analysis.

  16. Characterisation of sulphide-bearing waste-rock dumps using electrical resistivity imaging: the case study of the Rio Marina mining district (Elba Island, Italy).

    PubMed

    Mele, Mauro; Servida, Diego; Lupis, Domenico

    2013-07-01

    Sulphide-bearing mine dumps are potential sources of pollution when acid mine drainage (AMD) occurs. Because the generation of AMD depends on the volume and composition of waste materials, their characterisation is crucial for the evaluation of geochemical hazards and for the design of remediation strategies to minimise their environmental impact. In this paper, a cost-effective strategy for the characterisation of an inactive mine dump in the Rio Marina mining district (Elba Island, Italy) using earth resistivity imaging (ERI) is presented. As no information regarding the nature of waste rocks is found in reports for the mine, five ERI profiles were acquired at the top of the waste pile. The results show that waste rocks are heterogeneous with a maximum thickness of 30 m. Due to the large amounts of dispersed sulphide minerals, the waste rocks are characterised by an electrically conductive geophysical signature in comparison to the surrounding resistive metamorphic bedrock. A geostatistical approach was adopted to estimate the elevation of the edges of the mine dump, and the net volume of the waste rocks was computed through a raster analysis of the elevations of the upper and lower boundaries of the mine dump. High-conductivity anomalies were detected within the core of the mine dump. The integration of the hydrogeological, geochemical and geological framework of the Rio Marina mining district suggests that these anomalies could be a geophysical signature of subsurface regions where AMD is currently generated or stored, thus representing sources of environmental pollution.

  17. ERIT-Italia, the Italian Federation for Professionals Working in the Field of Drug Abuse.

    PubMed

    Nizzoli, Umberto; Foschini, Vittorio

    2002-11-01

    What is ERIT-Italia? In what cultural context was it founded and in what state were the services for drug dependency at that time? What has it produced in recent years? Can a professional association successfully work alongside administrations and governments to contribute to the development of effective treatment for drug addiction? It is these questions which are addressed in this description of the major Italian professional body concerned with drug misuse.

  18. Tectono-metamorphic evolution and magmatic processes in the thermo-metamorphic aureole of the Monte Capanne pluton (Elba Island, Northern Tyrrhenian Sea, Italy).

    NASA Astrophysics Data System (ADS)

    Morelli, M.; Pandeli, E.; Principi, G.

    2003-04-01

    Introduction In this work we present new structural and petrographic data collected in the thermo-metamorphic aureole of Monte Capanne (western Elba Island) and its metamorphic evolution. In the western Elba Island the Monte Capanne monzogranitic body (ca. 7 Ma) and its thermo-metamorphic aureole crop out. At least two different tectonic units can be distinguished: the Punta Le Tombe Unit, weak re-crystallized, and the Punta Nera Unit. In the latter one the re-crystallization is strong and a pre-intrusion tectono-metamorphic framework is evident (Morelli et al., 2002). The latter is mainly constituted by thermo-metamorphosed meta-ophiolites and meta-sedimentary successions previously correlated by Barberi et al. (1969) with the un-metamorphic ones (Complex IV and V of Trevisan, 1950) cropping out in the central-eastern Elba. According to Perrin (1975) and Reutter &Spohn (1982) a pre-intrusion tectono-metamorphic framework was recognized into such rocks. As suggested by Daniel &Jolivet (1995) complex relationships between metamorphic evolution and magmatic events are also recognizable. Geological Data The Punta Nera Unit crops out all around the Monte Capanne magmatic body and the primary contact with the underlying granitoid is somewhere preserved. This unit, strongly re-crystallized and locally crosscut by aplitic and porphyritic dikes, is represented by (Coli &Pandeli, 1997; Morelli, 2000) tectonized meta-serpentinites, meta-gabbros with rodingitic dikes, rare meta-basalts and meta-ophicalcites, meta-cherts, marbles, cherty meta-limestones, phyllites and meta-limestones with rare meta-arenites intercalations. A "pre-magmatic" tectono-metamorphic framework of this unit is well evident only in its meta-sedimentary portion. The meta-sediments are deformed by syn-metamorphic isoclinal folds caractherized by N-S trending axes, west dipping axial planes and easternward vergence. A later folding and flattening event clearly post-dated the above said folds and associated

  19. The design of the optical modules of the KM3NeT-Italia project towers

    NASA Astrophysics Data System (ADS)

    Leonora, Emanuele; Aiello, Sebastiano; Giordano, Valentina

    2016-07-01

    The KM3NeT-Italia project aims to construct a large volume underwater neutrino telescope, to be installed in the depths of the Mediterranean Sea. The R&D and mass production phases of the detection elements of the telescope, the optical modules, were entirely performed in the INFN-LNS site in the harbour of Catania. In November 2014 a first tower of 14 storeys equipped with 84 optical modules was successfully deployed in the Mediterranean Sea site. The design of the optical modules and their main components are described in this paper.

  20. Formation conditions of leucogranite dykes and aplite-pegmatite dykes in the eastern Mt. Capanne plutonic complex (Elba, Italy): fluid inclusion studies in quartz, tourmaline, andalusite and plagioclase

    NASA Astrophysics Data System (ADS)

    Bakker, Ronald J.; Schilli, Sebastian E.

    2016-02-01

    Leucogranite and aplite-pegmatite dykes are associated with the Mt. Capanne pluton (Elba) and partly occur in the thermally metamorphosed host rock (serpentinites). Crystallization conditions of these dykes in the late magmatic-hydrothermal stage are estimated from fluid inclusion studies and mineralogical characterisation, obtained from detailed microthermometry, Raman spectroscopy, and electron microprobe analyses. Fluid inclusion assemblages are analysed in andalusite, quartz, and plagioclase from the leucogranite dykes, and in tourmaline and quartz from the aplite-pegmatite dykes. The fluid inclusion assemblages record multiple pulses of low salinity H2O-rich magmatic and reduced metamorphic fluid stages. Magmatic fluids are characterized by the presence of minor amounts of CO2 and H3BO3, whereas the metamorphic fluids contain CH4 and H2. The highly reduced conditions are also inferred from the presence of native arsenic in some fluid inclusions. Several fluid inclusion assemblages reveal fluid compositions that must have resulted from mixing of both fluid sources. In leucogranite dykes, magmatic andalusite contains a low-density magmatic CO2-rich gas mixture with minor amounts of CH4 and H2. Accidentally trapped crystals (mica) and step-daughters (quartz and diaspore) are detected in some inclusions in andalusite. The first generation of inclusions in quartz that crystallized after andalusite contains a highly reduced H2O-H2 mixture and micas. The second type of inclusions in quartz from the leucogranite is similar to the primary inclusion assemblage in tourmaline from the aplite-pegmatite, and contains up to 4.2 mass% H3BO3, present as a sassolite daughter crystal or dissolved ions, in addition to a CO2-CH4 gas mixture, with traces of H2, N2, H2S, and C2H6. H2O is the main component of all these fluids ( x = 0.91 to 0.96) with maximally 7 mass% NaCl. Some accidentally trapped arsenolite and native arsenic are also detected. These fluids were trapped in the

  1. Rotation Period Determination for 254 Augusta, 465 Alekto 477 Italia, 515 Athalia, and 1061 Paeonia

    NASA Astrophysics Data System (ADS)

    Pilcher, Frederick

    2015-04-01

    Synodic rotation periods and amplitudes have been found for 254 Augusta 5.8949 ± 0.0001 hours, 0.75 to 0.58 magnitudes; 465 Alekto, 10.936 ± 0.001 hours, 0.14 ± 0.02 magnitudes with 3 maxima and minima per cycle; 477 Italia 19.413 ± 0.001 hours, 0.20 to 0.15 magnitudes with 3 very unequal maxima and minima per cycle; 515 Athalia 10.636 ± 0.001 hours, 0.21 ± 0.02 magnitudes; and 1061 Paeonia, 7.9971 ± 0.0001 hours, 1.00 ± 0.05 magnitudes.

  2. General Nobile and the Airship Italia: No Second-In-Command

    NASA Technical Reports Server (NTRS)

    Bendrick, Gregg A.

    2017-01-01

    The airship Italia, commanded by General Umberto Nobile, crashed during its return flight from the North Pole in 1928. Prior work has demonstrated the possibility that this crash was fatigue-related, due to significant sleep-deprivation on the part of its Commander, and to resulting errors in cognition and judgment. However, the underlying cause of the fatigue was likely due to the fact that the Commander did not have a Second-In-Command on board to take over duties while the Commander was allowed to rest. At that time the Second-In-Command was a formally designated position, and according to Nobiles previous writings was considered to be a necessary crew member on an airship.

  3. Quantification and analysis of geomorphic processes on a recultivated iron ore mine on the Italian island Elba using long-time ground-based LIDAR and photogrammetric data by an UAV

    NASA Astrophysics Data System (ADS)

    Haas, F.; Hilger, L.; Neugirg, F.; Umstädter, K.; Breitung, C.; Fischer, P.; Hilger, P.; Heckmann, T.; Dusik, J.; Kaiser, A.; Schmidt, J.; Della Seta, M.; Rosenkranz, R.; Becht, M.

    2015-10-01

    This study aims on the quantification and analysis of geomorphic processes on the barely vegetated slopes of a recultivated iron ore mine on the Italian island Elba using Terrestrial Lasercanning (TLS) and digital photogrammetry by UAV photographs over a period of 5 1/2 years. Beside this the study tried to work out the potential and the limitations of both methods to detect surface changes by geomorphic process dynamic within a natural environment. Both, UAV and TLS show the pattern of the erosion and accumulation processes on the investigated slope quite well, but the calculated amounts differ clearly between the methods. The reasons for these differences could be found in the different accuracies (variable level of detections) of the methods and the different viewing geometries. Both effects have an impact on the detectable process dynamic over different time scales on the slope and their calculated amounts, which in both cases can lead to an underestimation of erosion and accumulation by fluvial processes.

  4. Direct dating of Late Miocene-Early Pliocene compression on Elba Island: Is a new paradigm necessary for the opening of the Northern Tyrrhenian Sea?

    NASA Astrophysics Data System (ADS)

    Viola, Giulio; Torgersen, Espen; Mazzarini, Francesco; Musumeci, Giovanni; Garofalo, Paolo Stefano; van der Lelij, Roelant

    2017-04-01

    The northern Apennines accommodated the closure of the Liguro-Piemontese Ocean along the European and Adriatic continental margins. Crustal shortening via folding, eastward thrusting and stacking of oceanic and continental units during the westward subduction of Adria beneath the European plate shaped the orogenic prism starting in the Eocene and continuing to the Middle Miocene. Intrusive and volcanic rocks between 8.4 and 3 Ma crop out extensively in the northern Tyrrhenian Sea, and their emplacement in the inner portion of the belt is commonly interpreted as resulting from major crustal extension related to the Late Miocene-Pliocene opening of the northern Tyrrhenian Sea as a backarc basin. On the Island of Elba, which exposes the westernmost portion of the prism, the low-angle Zuccale fault (ZF) is generally interpreted as a major low-angle normal fault (LANF) whose Late Miocene activity would have greatly facilitated regional E-W extension in the geodynamic framework of the opening of the northern Tyrrhenian Sea between 10 and 5 Ma. In order to better constrain the kinematic meaning of the ZF and the timing of these important events, we have used the K-Ar method to date a set of brittle-ductile and brittle fault rocks cut by the ZF and sampled from its immediate footwall. A last sample from the brittle ZF itself is currently also being dated. The dated deformation zones in the ZF footwall are both thrusts with top-to-the east kinematics. They are undoubtedly cut by the brittle ZF and thus predate it; they are 1) the Calanchiole shear zone, formed by strongly sheared carbonate hornfelses and 2) the Capo Norsi fault, a brittle fault zone within serpentinites of the Ligurian sequence. While the Calanchiole shear zone developed coevally with the c. 6.2 Ma Porto Azzurro (PA) monzogranite, the Capo Norsi thrust led to the internal stacking of the PA contact aureole, and separates an upper complex that did not experience contact metamorphism from the underlying

  5. Single-station seismic noise measures, microgravity, and 3D electrical tomographies to assess the sinkhole susceptibility: the "Il Piano" area (Elba Island - Italy) case study

    NASA Astrophysics Data System (ADS)

    Pazzi, Veronica; Di Filippo, Michele; Di Nezza, Maria; Carlà, Tommaso; Bardi, Federica; Marini, Federico; Fontanelli, Katia; Intrieri, Emanuele; Fanti, Riccardo

    2017-04-01

    Sudden subsurface collapse, cavities, and surface depressions, regardless of shape and origin, as well as doline are currently indicate by means of the term "sinkhole". This phenomenon can be classified according to a large variety of different schemes, depending on the dominant formation processes (soluble rocks karstic processes, acidic groundwater circulation, anthropogenic caves, bedrock poor geomechanical properties), and on the geological scenario behind the development of the phenomenon. Considering that generally sinkholes are densely clustered in "sinkhole prone areas", detection, forecasting, early warning, and effective monitoring are key aspects in sinkhole susceptibility assessment and risk mitigation. Nevertheless, techniques developed specifically for sinkhole detection, forecasting and monitoring are missing, probably because of a general lack of sinkhole risk awareness, and an intrinsic difficulties involved in detecting precursory sinkhole deformations before collapse. In this framework, integration of different indirect/non-invasive geophysical methods is the best practice approach. In this paper we present the results of an integrated geophysical survey at "Il Piano" (Elba Island - Italy), where at least nine sinkholes occurred between 2008 and 2014. 120 single-station seismic noise measures, 17 3D electrical tomographies (min area 140.3 m2, max area 10,188.9 m2; min electrode spacing 2 m, max electrode spacing 5 m), 964 measurement of microgravity spaced in a grid of 6 m to 8 m were carried out at the study area. The most likely origin for these sinkholes was considered related to sediment net erosion from the alluvium, caused by downward water circulation between aquifers. Therefore, the goals of the study were: i) obtaining a suitable geological and hydrogeological model of the area; ii) detecting possible cavities which could evolve in sinkholes, and finally iii) assess the sinkhole susceptibility of the area. Among the results of the

  6. The Nature and Evolution of Fluid-Related Weakening Mechanisms Along a Continental Low-Angle Normal Fault: the Zuccale Fault, Elba Island, Italy

    NASA Astrophysics Data System (ADS)

    Smith, S. A.; Holdsworth, R. E.; Collettini, C.; MacPherson, C. G.; Pearce, M. A.; Faulkner, D.

    2008-12-01

    Despite extensive research concerning the mechanical significance and geometric evolution of low-angle normal faults, few studies have focussed on the importance of the fault rock material which is generated during prolonged slip and exhumation. The Zuccale fault on the Island of Elba is closely associated with syn- tectonic igneous intrusions, and it possesses a complex fault rock 'stratigraphy' which records the interaction between multiple deformation mechanisms and fluids derived from distinct crustal reservoirs. Optical- and scanning-electron microscopy, combined with XRD and stable isotope analyses, reveal systematic changes in fault rock chemistry and texture: 1) Cataclasis and dissolution-precipitation creep were the dominant deformation mechanisms during the early stages of fault activity. Cataclasis facilitated the influx of chemically active fluids, leading to widespread syn-tectonic growth of weak phyllosilicate minerals, including talc and chlorite. Crystal-plasticity was important within calcite-rich fault rocks which initially deformed at depths of ~6-8km. Calcite grains (~10μm in diameter) possess a strong C-axis preferred orientation, suggesting that they experienced dynamic recrystallisation by dislocation creep. These calcite-mylonites were crosscut by vein material which was progressively sheared and recrystallised, indicating cyclic brittle-ductile deformation. During the later stages of fault activity, granular flow became an important deformation mechanism. Rolling and sliding of grains past one another was accommodated along clay-lined grain boundaries; 2) During exhumation, dolomite was superseded by calcite as the dominant syn- tectonic fault cement. Dolomite veins within the fault core record transiently high fluid pressures followed by mineral sealing and fault strengthening. The δ13CV-PDB signature of such vein dolomite is strongly clustered around a mean value of -5.7‰, whilst δ18OV-SMOW varies between 10‰ to14‰. These values

  7. Genetic diversity in somatic mutants of grape (Vitis vinifera) cultivar Italia based on random amplified polymorphic DNA.

    PubMed

    Maia, S H Z; Mangolin, C A; Collet, S A O; Machado, M F P S

    2009-01-13

    Random amplified polymorphic DNA (RAPD) markers were used to detect polymorphism and to examine relationships among four table grape clones from northwestern Paraná, in southern Brazil. The 10 primers used for RAPD fingerprints generated 126 reproducible fragments, of which 63, 68, 76, and 72 were polymorphic in cultivars Italia, Rubi, Benitaka, and Brasil, respectively. Among the primers, OPP-08 generated the highest number of fragments, whereas OPE-15 was the most efficient for discriminating polymorphic fragments. The distribution of the clones by cluster analysis indicated that there were no differences in RAPD markers between the colored mutant and the original clone (cultivar Italia), supporting the hypothesis that the non-colored and the colored mutant are the same cultivar. However, we found high levels of polymorphism within and between the cultivars Italia, Rubi, Benitaka, and Brasil (65.1%), contrary to a previous hypothesis that the four clones are genetically uniform. This confirmed our expectation of genetic variation among the clones and within each clone. We conclude that the primers are useful for analyzing the development of the genetic diversity within each of these clones.

  8. The Interreg IV Italia-Austria "SeismoSAT" project: connecting seismic data centers via satellite

    NASA Astrophysics Data System (ADS)

    Pesaresi, D.; Lenhardt, W.; Rauch, M.; Živčić, M.; Steiner, R.; Fabris, P.; Bertoni, M.

    2014-06-01

    Since 2002 OGS (Istituto Nazionale di Oceanografia e di Geofisica Sperimentale) in Udine (Italy), the Zentralanstalt für Meteorologie und Geodynamik (ZAMG) in Vienna (Austria), and the Agencija Republike Slovenije za Okolje (ARSO) in Ljubljana (Slovenia) are using the Antelope software suite as the main tool for collecting, analyzing, archiving and exchanging seismic data in real time, initially in the framework of the EU Interreg IIIA project "Trans-national seismological networks in the South-Eastern Alps" (Bragato et al., 2004, 2010). The data exchange has proved to be effective and very useful in case of seismic events near the borders between Italy, Austria and Slovenia, where the poor single national seismic networks coverage precluded a correct localization, while the usage of common data from the integrated networks improves considerably the overall reliability of real time seismic monitoring of the area (Fig. 1). At the moment the data exchange between the seismic data centers relies on their internet connections: this however is not an ideal condition for civil protection purposes, since the reliability of standard internet connections is poor. For this reason in 2012 the Protezione Civile della Provincia Autonoma di Bolzano in Bolzano (PCBZ, Italy), OGS, ZAMG subsidiary in Tirol (ZAMG Tirol) and ARSO joined in the Interreg IV Italia-Austria Project "SeismoSAT" (Progetto SeismoSAT, 2012) aimed in connecting the seismic data centers in real time via satellite. ARSO does not belong to the Interreg Italia-Austria region: for this reason ARSO joined the SeismoSAT project as an "associated partner", which, according to Interreg rules can not be funded. ARSO participation in the project is therefore at the beginning limited in benefiting only indirectly from improvement in the robustness of the data exchange between the other data centers, while eventually fully taking part in the project if other sources of funding will be available. The project is in a

  9. U-Th-Ra disequilibria in sediments of the Dora Baltea river (Italia)

    NASA Astrophysics Data System (ADS)

    Chabaux, F.; Deloche, A.; Pelt, E.; Granet, M.; Perrone, Th.; Boutin, R.; Viville, D.; Rihs, S.; Stille, P.

    2012-04-01

    In order to constrain the transfer time of sediments in Alpine rivers, we propose to use the U-series nuclides approach recently developed for Himalayan rivers (e.g., Chabaux et al., 2008; Granet et al., 2010). Therefore, a series of bank sediments has beeen collected along the Dora Baltea river (Italia), one of the Po's tributaries draining the southern slope of the Mont Blanc Massif. In addition to U series nuclides, major and trace element concentrations and Sr and Nd isotope ratios have been analyzed for each sample. The study indicates that the (234U/238U)-, (230Th/234U)- and the (226Ra/230Th)- activity ratios are very similar for all the samples, whereas the 230Th/232Th ratios can differ from one sample to another. Such a variation, consistent with the Sr and Nd isotope data, is certainly the consequence of mineralogical heterogeneities in the samples. This suggests that the use of 238U-230Th-232Th systematics alone is probably insufficient for constraining the transfer time of sediments in the Po rivers alluvial plain, whereas the combination of 238U-230Th disequilibrium with the 230Th-226Ra disequilibrium can help to constrain such time information.

  10. The Trigger and Data Acquisition System for the KM3NeT-Italia towers

    NASA Astrophysics Data System (ADS)

    Favaro, M.; Chiarusi, T.; Giacomini, F.; Manzali, M.; Margiotta, A.; Pellegrino, C.

    2016-04-01

    KM3NeT-Italia is an INFN project supported with Italian PON fundings for building the core of the Italian node of the KM3NeT neutrino telescope. The detector, made of 700 10'' Optical Modules (OMs) lodged along 8 vertical structures called towers, will be deployed starting from fall 2015 at the KM3NeT-Italy site, about 80 km off Capo Passero, Italy, 3500 m deep. The all data to shore approach is used to reduce the complexity of the submarine detector, demanding for an on-line trigger integrated in the data acquisition system running in the shore station, called TriDAS. Due to the large optical background in the sea from 40K decays and bioluminescence, the throughput from the underwater detector can range up to 30 Gbps. This puts strong constraints on the design and performances of the TriDAS and of the related network infrastructure. In this contribution the technology behind the implementation of the TriDAS infrastructure is reviewed, focusing on the relationship between the various components and their performances. The modular design of the TriDAS, which allows for its scalability up to a larger detector than the 8-tower configuration is also discussed.

  11. The ODAS Italia 1 buoy: More than forty years of activity in the Ligurian Sea

    NASA Astrophysics Data System (ADS)

    Canepa, Elisa; Pensieri, Sara; Bozzano, Roberto; Faimali, Marco; Traverso, Pierluigi; Cavaleri, Luigi

    2015-06-01

    The Ligurian Sea plays a relevant role in driving both the circulation of the Western Mediterranean Sea and the weather and climate of the area. In order to better understand the peculiarities of this basin, the Oceanographic Data Acquisition System (ODAS) Italia 1 buoy was developed and deployed in the early '70s. Throughout the years, the buoy has been fitted with updated measuring and data acquiring systems. Since 2003 the buoy has been part of the Mediterranean Moored Multi-sensor Array network of fixed open ocean observatories with the W1-M3A identifier and presently constitutes one of the Mediterranean sites of the European FixO3 network. Recently, a deep-ocean sub-surface mooring line was, and is, deployed close to it in relation to specific projects. This multidisciplinary observing system is able to perform both long-term operational and ad-hoc monitoring from the lower atmosphere to the deep ocean. It is used for analysis of air-sea interaction processes, study of the physical proprieties of the water column, bio-geo-chemical monitoring of the sea, meteorological and oceanographic model evaluation, calibration of remotely sensed measurements, and development of innovative marine monitoring technologies. After reporting some historical notes and the description of the observing system, this paper summarises and reviews the main oceanographic and atmospheric studies performed during the last 15 years using the data acquired on board.

  12. The Interreg IV Italia-Austria "SeismoSAT" Project: connecting Seismic Data Centers via satellite

    NASA Astrophysics Data System (ADS)

    Pesaresi, Damiano; Lenhardt, Wolfgang; Rauch, Markus; Zivcic, Mladen; Steiner, Rudolf; Fabris, Paolo; Bertoni, Michele

    2013-04-01

    Since 2002 the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale - OGS in Udine (Italy), the Zentralanstalt für Meteorologie und Geodynamik (ZAMG) in Vienna (Austria), and the Agencija Republike Slovenije za okolje (ARSO) in Ljubljana (Slovenija) are using the Antelope software suite as the main tool for collecting, analyzing, archiving and exchanging seismic data in real time, initially in the framework of the EU Interreg IIIA project "Trans-national seismological networks in the South-Eastern Alps". The data exchange has proved to be effective and very useful in case of seismic events near the borders between Italy, Austria and Slovenia, where the poor single national seismic networks coverage precluded a correct localization, while the usage of common data from the integrated networks improves considerably the overall reliability of real time seismic monitoring of the area. At the moment the data exchange between the seismic data centers relies on internet: this however is not an ideal condition for civil protection purposes, since internet reliability is poor. For this reason in 2012 the Protezione Civile della Provincia Autonoma di Bolzano in Bolzano (Italy) joined OGS, ZAMG and ARSO in the Interreg IV Italia-Austria Project "SeismoSAT" aimed in connecting the seismic data centers in real time via satellite. The general schema of the project, including first data bandwith estimates and a possible architecture will be illustrated.

  13. Characterization of 750 Large Area Photomultipliers for the KM3NeT-Italia towers

    SciTech Connect

    Leonora, Emanuele; Aiello, S.; Giordano, V.

    2015-07-01

    The KM3NeT European experiment aims to construct a large volume underwater neutrino telescope, in the depths of the Mediterranean Sea. Thanks to a dedicated funding by the Italian Ministry of Education, University and Research, in its first phase named KM3NeT-Italia, an 8-towers detector is under construction, equipped with 672 optical sensors. The detection element of the telescope, the 'optical module', is composed by a 13-inch high-pressure glass-vessel that contains a single 10-inch photomultiplier. As the key sensor, all the characteristics of the photomultiplier have a severe impact on the performance of the whole detector. The selected photomultiplier was the 10-inch R7081 PMT produced by Hamamatsu. In the frame of the optical modules mass production, performed in the INFN-LNS site of Catania, 750 photomultipliers have been tested by means of a dedicated test bench. The paper deals with the main results obtained from the massive photomultipliers measurements, which exhibited that such kind of devices comply with the general requirements imposed by the project. (authors)

  14. Quantification and analysis of geomorphic processes on a recultivated iron ore mine on the Italian island of Elba using long-term ground-based lidar and photogrammetric SfM data by a UAV

    NASA Astrophysics Data System (ADS)

    Haas, Florian; Hilger, Ludwig; Neugirg, Fabian; Umstädter, Kathrin; Breitung, Christian; Fischer, Peter; Hilger, Paula; Heckmann, Tobias; Dusik, Jana; Kaiser, Andreas; Schmidt, Jürgen; Della Seta, Marta; Rosenkranz, Ruben; Becht, Michael

    2016-05-01

    This study focuses on the quantification and analysis of geomorphic processes on the barely vegetated slopes of a recultivated iron ore mine on the Italian island of Elba using photographs from terrestrial laser scanning (TLS) and digital photogrammetry by an unmanned aerial vehicle (UAV) over a period of 5 1/2 years. Beside this, the study tried to work out the potential and the limitations of both methods to detect surface changes by geomorphic process dynamics within a natural environment. Both UAV and TLS show the pattern of the erosion and accumulation processes on the investigated slope quite well, but the calculated amounts differ clearly between the methods. The reasons for these differences could be found in the different accuracies (variable level of detections) of the methods and the different viewing geometries. Both effects have an impact on the detectable process dynamics over different timescales on the slope and their calculated amounts, which in both cases can lead to an underestimation of erosion and accumulation by fluvial processes.

  15. Heterogeneous brittle-ductile deformation at shallow crustal levels under high thermal conditions: The case of a synkinematic contact aureole in the inner northern Apennines, southeastern Elba Island, Italy

    NASA Astrophysics Data System (ADS)

    Papeschi, Samuele; Musumeci, Giovanni; Mazzarini, Francesco

    2017-10-01

    We present an example of interaction between magmatism and tectonics at shallow crustal levels. In the Late Miocene the metamorphic units of the eastern Elba Island (northern Apennines) were intruded at very shallow crustal levels by a large pluton (> 60 km2) with the development of an hectometre-sized contact aureole defined by growth of low-pressure/high-temperature mineral assemblages (Pmax < 0.2 GPa, Tmax 650 °C). Structural data show that the contact aureole is associated with a km-sized antiform of the foliation and by several metre- to decametre-thick high-strain domains consisting of strongly foliated rocks containing synkinematic HT/LP mineral assemblages and ductile shear zones of variable thickness. These shear zones are characterized by a mylonitic foliation variably overprinted by cataclasis. Quartz microfabrics indicate that the dynamic crystallization processes progressively changed from grain boundary migration, associated with the thermal peak of contact metamorphism, to subgrain rotation and bulging recrystallization, the latter mostly associated with the cataclastic overprint. These transitions of recrystallization mechanisms in quartz are related to a progressive decrease of temperature during deformation. Deformation accompanied the development and cooling of the contact aureole, which recorded the switch from high temperature ductile to low temperature brittle conditions. The geometry of the studied deformation structures is consistent with the constraints of the regional tectonic evolution and its local interaction with the localized and transient thermal anomaly related to the coeval emplacement of igneous rocks.

  16. Cycling power output produced during flat and mountain stages in the Giro d'Italia: a case study.

    PubMed

    Vogt, Stefan; Schumacher, Yorck Olaf; Blum, Andreas; Roecker, Kai; Dickhuth, Hans-Hermann; Schmid, Andreas; Heinrich, Lothar

    2007-10-01

    Until recently, the physiological demands of cycling competitions were mostly reflected by the measurement of heart rate and the indirect estimation of exercise intensity. The purpose of this case study was to illustrate the varying power output of a professional cyclist during flat and mountain stages of a Grand Tour (Giro d'Italia). Nine stage recordings of a cyclist of the 2005 Giro d'Italia were monitored using a mobile power measurement device (SRM Trainingssystem, Julich, Germany), which recorded direct power output and heart rate. Stages were categorized into flat (n = 5) and mountain stages (n = 4). Data were processed electronically, and the overall mean power in flat and mountain stages and maximal mean power for various durations were calculated. Mean power output was 132 W +/- 26 (2.0 W x kg(-1) +/- 0.4) for the flat and 235 W +/- 10 (3.5 W x kg(-1) +/- 0.1) for the mountain stages. Mountain stages showed higher maximal mean power (367 W) for longer durations (1800 s) than flat stages (239 W). Flat stages are characterized by a large variability of power output with short bursts of high power and long periods with reduced intensity of exercise, whereas mountain stages mostly require submaximal, constant power output over longer periods.

  17. Effects of elicitors on the production of resveratrol and viniferins in cell cultures of Vitis vinifera L. cv Italia.

    PubMed

    Santamaria, Anna Rita; Mulinacci, Nadia; Valletta, Alessio; Innocenti, Marzia; Pasqua, Gabriella

    2011-09-14

    Methyl jasmonate, jasmonic acid and chitosan were tested as elicitors on cell suspension cultures obtained from Vitis vinifera cv Italia to investigate their effect on stilbene production. Stilbene accumulation in the callus, grown under nonelicited conditions, was also investigated. Calli and cell suspensions were obtained in a B5 culture medium supplemented with 0.2 mg L(-1) NAA and 1 mg L(-1) KIN. Stilbene determination was achieved by HPLC/DAD/MS. Whereas callus biosynthesized only piceid, cell suspensions elicited with jasmonates produced several stilbenes, mainly viniferins. In suspended cells, methyl jasmonate and jasmonic acid were the most effective in stimulating stilbene biosynthesis, whereas chitosan was less effective; in fact, the amount of stilbenes obtained with this elicitor was not significantly different from that obtained for the control cells. The maximum production of total stilbenes was at day 20 of culture with 0.970 and 1.023 mg g(-1) DW for MeJA and JA, respectively.

  18. SETI-Italia 2003 status report and first results of a KL transform algorithm for ETI signal detection

    NASA Astrophysics Data System (ADS)

    Montebugnoli, S.; Bortolotti, C.; Cattani, A.; Maccaferri, A.; Orlati, A.; Poloni, M.; Poppi, S.; Monari, J.; Roma, M.; Pari, P. P.; Teodorani, M.; Righini, S.; Maccone, C.; Caliendo, D.; Cosmovici, C. B.; D'Amico, N.

    2006-02-01

    SETI-Italia is the Italian national SETI Program. It is run as a part of the Italian Bioastronomy Project, by IRA (Istituto di Radioastronomia) a subsidiary of the Istituto Nazionale di Astrofisica. At the moment, Italy is the only European country conducting a continuous SETI “listening” program, while occasional SETI searches may be conducted in France and the Ukraine. Outside Europe, continuous SETI programs are conducted in the USA, Australia and Argentina. The SETI-Italia activities started early in 1998 with a Serendip IV system connected in piggy-back mode to the Medicina VLBI 32-m antenna dish. In the years 2002/2003, considerable efforts were devoted to set up a fast computational system capable of computing the KLT (Karhunen Loève transform). This is a virtually new mathematical procedure in SETI, and is much more general than the FFT. It can search for the presence of signals both narrow-band and wide-band embedded in noise both coloured and white. The mathematical features the KLT have already been described in this Conference by Claudio Maccone [Innovative SETI by the KLT, Pešek Lecture 2003, paper # IAA.9.1.01 presented in Bremen, in this 2003 International Astronautical Congress [1]; Telecommunications, KLT and Relativity, vol. 1, IPI Press, Colorado Springs, CO, 1994, ISBN #1-880930-04-8 [2].]. Our software implementation of the KLT follows these lines and also is indebted to some basic ideas put forward by Robert S. Dixon [On the detection of unknown signals, in: G. Seth Shostak (Ed.), Third Decennial US USSR Conference on SETI, Astronomical Society of the Pacific Conference Series, vol. 47, 1993, pp. 128 140] of the Ohio State Radio Observatory as early as 1993.

  19. Inertial bioluminescence rhythms at the Capo Passero (KM3NeT-Italia) site, Central Mediterranean Sea.

    PubMed

    Aguzzi, J; Fanelli, E; Ciuffardi, T; Schirone, A; Craig, J

    2017-03-23

    In the deep sea, the sense of time is dependent on geophysical fluctuations, such as internal tides and atmospheric-related inertial currents, rather than day-night rhythms. Deep-sea neutrino telescopes instrumented with light detecting Photo-Multiplier Tubes (PMT) can be used to describe the synchronization of bioluminescent activity of abyssopelagic organisms with hydrodynamic cycles. PMT readings at 8 different depths (from 3069 to 3349 m) of the NEMO Phase 2 prototype, deployed offshore Capo Passero (Sicily) at the KM3NeT-Italia site, were used to characterize rhythmic bioluminescence patterns in June 2013, in response to water mass movements. We found a significant (p < 0.05) 20.5 h periodicity in the bioluminescence signal, corresponding to inertial fluctuations. Waveform and Fourier analyses of PMT data and tower orientation were carried out to identify phases (i.e. the timing of peaks) by subdividing time series on the length of detected inertial periodicity. A phase overlap between rhythms and cycles suggests a mechanical stimulation of bioluminescence, as organisms carried by currents collide with the telescope infrastructure, resulting in the emission of light. A bathymetric shift in PMT phases indicated that organisms travelled in discontinuous deep-sea undular vortices consisting of chains of inertially pulsating mesoscale cyclones/anticyclones, which to date remain poorly known.

  20. Inertial bioluminescence rhythms at the Capo Passero (KM3NeT-Italia) site, Central Mediterranean Sea

    PubMed Central

    Aguzzi, J.; Fanelli, E.; Ciuffardi, T.; Schirone, A.; Craig, J.; Aiello, S.; Ameli, F.; Anghinolfi, M.; Barbarino, G.; Barbarito, E.; Beverini, N.; Biagi, S.; Biagioni, A.; Bouhadef, B.; Bozza, C.; Cacopardo, G.; Calamai, M.; Calì, C.; Capone, A.; Caruso, F.; Cecchini, S.; Ceres, A.; Chiarusi, T.; Circella, M.; Cocimano, R.; Coniglione, R.; Costa, M.; Cuttone, G.; D’Amato, C.; D’Amico, A.; De Bonis, G.; De Luca, V.; Deniskina, N.; Distefano, C.; Di Mauro, L. S.; Fermani, P.; Ferrara, G.; Flaminio, V.; Fusco, L. A.; Garufi, F.; Giordano, V.; Gmerk, A.; Grasso, R.; Grella, G.; Hugon, C.; Imbesi, M.; Kulikovskiy, V.; Larosa, G.; Lattuada, D.; Leismüller, K. P.; Leonora, E.; Litrico, P.; Lonardo, A.; Longhitano, F.; Presti, D. Lo; Maccioni, E.; Margiotta, A.; Marinelli, A.; Martini, A.; Masullo, R.; Mele, R.; Migliozzi, P.; Migneco, E.; Miraglia, A.; Mollo, C. M.; Mongelli, M.; Morganti, M.; Musico, P.; Musumeci, M.; Nicolau, C. A.; Orlando, A.; Orzelli, A.; Papaleo, R.; Pellegrino, C.; Pellegriti, M. G.; Perrina, C.; Piattelli, P.; Poma, E.; Pulvirenti, S.; Raffaelli, F.; Randazzo, N.; Riccobene, G.; Rovelli, A.; Sanguineti, M.; Sapienza, P.; Sciacca, V.; Sgura, I.; Simeone, F.; Sipala, V.; Speziale, F.; Spitaleri, A.; Spurio, M.; Stellacci, S. M.; Taiuti, M.; Terreni, G.; Trasatti, L.; Trovato, A.; Versari, F.; Vicini, P.; Viola, S.; Vivolo, D.

    2017-01-01

    In the deep sea, the sense of time is dependent on geophysical fluctuations, such as internal tides and atmospheric-related inertial currents, rather than day-night rhythms. Deep-sea neutrino telescopes instrumented with light detecting Photo-Multiplier Tubes (PMT) can be used to describe the synchronization of bioluminescent activity of abyssopelagic organisms with hydrodynamic cycles. PMT readings at 8 different depths (from 3069 to 3349 m) of the NEMO Phase 2 prototype, deployed offshore Capo Passero (Sicily) at the KM3NeT-Italia site, were used to characterize rhythmic bioluminescence patterns in June 2013, in response to water mass movements. We found a significant (p < 0.05) 20.5 h periodicity in the bioluminescence signal, corresponding to inertial fluctuations. Waveform and Fourier analyses of PMT data and tower orientation were carried out to identify phases (i.e. the timing of peaks) by subdividing time series on the length of detected inertial periodicity. A phase overlap between rhythms and cycles suggests a mechanical stimulation of bioluminescence, as organisms carried by currents collide with the telescope infrastructure, resulting in the emission of light. A bathymetric shift in PMT phases indicated that organisms travelled in discontinuous deep-sea undular vortices consisting of chains of inertially pulsating mesoscale cyclones/anticyclones, which to date remain poorly known. PMID:28332561

  1. Inertial bioluminescence rhythms at the Capo Passero (KM3NeT-Italia) site, Central Mediterranean Sea

    NASA Astrophysics Data System (ADS)

    Aguzzi, J.; Fanelli, E.; Ciuffardi, T.; Schirone, A.; Craig, J.; Aiello, S.; Ameli, F.; Anghinolfi, M.; Barbarino, G.; Barbarito, E.; Beverini, N.; Biagi, S.; Biagioni, A.; Bouhadef, B.; Bozza, C.; Cacopardo, G.; Calamai, M.; Calì, C.; Capone, A.; Caruso, F.; Cecchini, S.; Ceres, A.; Chiarusi, T.; Circella, M.; Cocimano, R.; Coniglione, R.; Costa, M.; Cuttone, G.; D’Amato, C.; D’Amico, A.; de Bonis, G.; de Luca, V.; Deniskina, N.; Distefano, C.; di Mauro, L. S.; Fermani, P.; Ferrara, G.; Flaminio, V.; Fusco, L. A.; Garufi, F.; Giordano, V.; Gmerk, A.; Grasso, R.; Grella, G.; Hugon, C.; Imbesi, M.; Kulikovskiy, V.; Larosa, G.; Lattuada, D.; Leismüller, K. P.; Leonora, E.; Litrico, P.; Lonardo, A.; Longhitano, F.; Presti, D. Lo; Maccioni, E.; Margiotta, A.; Marinelli, A.; Martini, A.; Masullo, R.; Mele, R.; Migliozzi, P.; Migneco, E.; Miraglia, A.; Mollo, C. M.; Mongelli, M.; Morganti, M.; Musico, P.; Musumeci, M.; Nicolau, C. A.; Orlando, A.; Orzelli, A.; Papaleo, R.; Pellegrino, C.; Pellegriti, M. G.; Perrina, C.; Piattelli, P.; Poma, E.; Pulvirenti, S.; Raffaelli, F.; Randazzo, N.; Riccobene, G.; Rovelli, A.; Sanguineti, M.; Sapienza, P.; Sciacca, V.; Sgura, I.; Simeone, F.; Sipala, V.; Speziale, F.; Spitaleri, A.; Spurio, M.; Stellacci, S. M.; Taiuti, M.; Terreni, G.; Trasatti, L.; Trovato, A.; Versari, F.; Vicini, P.; Viola, S.; Vivolo, D.

    2017-03-01

    In the deep sea, the sense of time is dependent on geophysical fluctuations, such as internal tides and atmospheric-related inertial currents, rather than day-night rhythms. Deep-sea neutrino telescopes instrumented with light detecting Photo-Multiplier Tubes (PMT) can be used to describe the synchronization of bioluminescent activity of abyssopelagic organisms with hydrodynamic cycles. PMT readings at 8 different depths (from 3069 to 3349 m) of the NEMO Phase 2 prototype, deployed offshore Capo Passero (Sicily) at the KM3NeT-Italia site, were used to characterize rhythmic bioluminescence patterns in June 2013, in response to water mass movements. We found a significant (p < 0.05) 20.5 h periodicity in the bioluminescence signal, corresponding to inertial fluctuations. Waveform and Fourier analyses of PMT data and tower orientation were carried out to identify phases (i.e. the timing of peaks) by subdividing time series on the length of detected inertial periodicity. A phase overlap between rhythms and cycles suggests a mechanical stimulation of bioluminescence, as organisms carried by currents collide with the telescope infrastructure, resulting in the emission of light. A bathymetric shift in PMT phases indicated that organisms travelled in discontinuous deep-sea undular vortices consisting of chains of inertially pulsating mesoscale cyclones/anticyclones, which to date remain poorly known.

  2. Body Water Status and Short-term Maximal Power Output during a Multistage Road Bicycle Race (Giro d'Italia 2014).

    PubMed

    Pollastri, L; Lanfranconi, F; Tredici, G; Burtscher, M; Gatterer, H

    2016-04-01

    An investigation of whether body water changes during the Giro d'Italia affected average maximal mean power (MMP) of different time durations and to establish whether phase-angle and body cell mass (BCM) are related to MMP in elite cyclists. Approximately 2 h after each stage of the race, a bioelectrical impedance analysis was performed on 8 cyclists and analysed according to bioelectrical impedance vector analyses. Additionally, MMP of different time durations were recorded during each stage. Body mass increased (p<0.001), vector-length shortened (p<0.001) and MMP15 (maximal mean power for 15 s; p=0.043) decreased in the course of the Giro d'Italia. The shortening of the vector was negatively related to MMP10 (r=- 0.749, p=0.032) and MMP15 (r=- 0.735, p=0.038) during stage 16 (heavy mountain-stage) and MMP60 (r=- 0.751, p=0.032), MMP300 (r=- 0.739, p=0.036) and MMP1800 (r=- 0.769, p=0.026) during stage 19 (time-trial). Additionally, the baseline phase-angle and BCM were associated to MMP15 best (r=0.781, p=0.022 and 0.756, p=0.030, respectively). In the course of the Giro d'Italia, MMP15 decreased, indicating progressive fatigue. The vector-length shortening and to some extent the body mass increase indicate that cyclists gained body water during the race. This gain was positively associated with performance during the last stages, possibly due to improved thermoregulation. Furthermore, phase-angle and BCM, shown to be linked to cellular function and to represent metabolic active tissue, reflect individual MMP of short duration in professional road cyclists. © Georg Thieme Verlag KG Stuttgart · New York.

  3. Use of the Oto lung donor score to analyze the 2010 donor pool of the Nord Italia Transplant program.

    PubMed

    Porro, G A; Valenza, F; Coppola, S; Froio, S; Benazzi, E; De Fazio, N; Santambrogio, L; D'Armini, A M; Loy, M; Ravini, M; Lucianetti, A; Moretti, M P; Vesconi, S; Scalamogna, M; Gattinoni, L

    2012-09-01

    The feasibility and utility of a lung donor score that has been recently proposed was tested among a pool of lung donors referred to the Nord Italia Transplant program (NITp) organ procurement organization. Each lung donor was assigned an Oto score including, age, smoking history, chest X-ray, secretions and ratio of arterial oxygen tension to inspired oxygen fraction (PaO(2)/FiO(2)). Based on clinical compromise, each variable received a score between 0 and 3, except for PaO(2)/FiO(2), which was scored between 0 and 6 given its overall relevance. Throughout 2010, 201 multiorgan donors were initially considered to be potential lung donors. Among these, 59 (29.4%) eventually yielded 67 lung transplantations (named "Used group"). Among the 142 (70.6%) refused lungs, 28 were not used due to logistic or medical problems ("general exclusion" group, GE) and 114, because of poor lung function ("lung exclusion" group, LE). Median lung donor scores were 1 (range, 0 to 3), 4 (range, 2.5 to 6.5), and 7 (range, 5 to 9) in the Used, GE, and LE groups, respectively (one-way analysis of variance, P < .001). Some donors with Oto scores ≤7 worsened over time so that the score had significantly increased by the time of organ retrieval. Overall, subjects who died after lung transplantation were characterized by higher lung donor scores, (2 [1-4] versus 0.5 [0-3], P = .003). Our analysis suggested that the use of a donor score as a dynamic tool over the donation process was of great utility to describe and analyze a pool of lung donors. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. NaNet3: The on-shore readout and slow-control board for the KM3NeT-Italia underwater neutrino telescope

    NASA Astrophysics Data System (ADS)

    Ammendola, R.; Biagioni, A.; Frezza, O.; Lo Cicero, F.; Martinelli, M.; Paolucci, P. S.; Pontisso, L.; Simula, F.; Vicini, P.; Ameli, F.; Nicolau, C. A.; Pastorelli, E.; Simeone, F.; Tosoratto, L.; Lonardo, A.

    2016-04-01

    The KM3NeT-Italia underwater neutrino detection unit, the tower, consists of 14 floors. Each floor supports 6 Optical Modules containing front-end electronics needed to digitize the PMT signal, format and transmit the data and 2 hydrophones that reconstruct in real-time the position of Optical Modules, for a maximum tower throughput of more than 600 MB/s. All floor data are collected by the Floor Control Module (FCM) board and transmitted by optical bidirectional virtual point-to-point connections to the on-shore laboratory, each FCM needing an on-shore counterpart as communication endpoint. In this contribution we present NaNet3, an on-shore readout board based on Altera Stratix V GX FPGA able to manage multiple FCM data channels with a capability of 800 Mbps each. The design is a NaNet customization for the KM3NeT-Italia experiment, adding support in its I/O interface for a synchronous link protocol with deterministic latency at physical level and for a Time Division Multiplexing protocol at data level.

  5. Skin extracts from 2 Italian table grapes (Italia and Palieri) inhibit tissue factor expression by human blood mononuclear cells.

    PubMed

    Milella, Rosa Anna; Antonacci, Donato; Crupi, Pasquale; Incampo, Francesca; Carrieri, Cosimo; Semeraro, Nicola; Colucci, Mario

    2012-08-01

    Grape and its products such as red wine and grape juice have well-known antithrombotic properties, which have been attributed to their high content in polyphenolic compounds. Most studies on the mechanisms underlying these beneficial effects, among which the suppression of tissue factor (TF) synthesis in blood mononuclear cells (MNC) and vascular endothelium is a prominent one, have been performed with purified polyphenols, while little is known about the effect of fresh grapes which contain a multitude of phytochemicals whose interaction may lead to different cell responses. In this study, we investigated the effect of grape skin extracts (GSEs) on TF expression in isolated blood MNC and in whole blood. Alcoholic extracts from skins of 2 grape varieties (Palieri and Italia) inhibited TF expression in lipopolysaccharide (LPS)-stimulated MNC in a concentration-dependent manner with ≥90% inhibition of TF activity and antigen at 6 μg/mL of gallic acid equivalents. Noteworthy, GSEs were also able to inhibit the appearance of TF in whole blood challenged with LPS. The 2 grape varieties displayed a fairly similar TF-inhibiting capacity despite marked differences in phenolic profile. When selected purified polyphenols were tested, their ability to inhibit TF expression was markedly lower as compared to grape extracts, whereas a mixture of some representative polyphenols was much more efficient, supporting the occurrence of a synergistic effect. Given the key role of cell TF in thrombotic diseases, the inhibition of MNC-mediated clotting activation, if confirmed by in vivo studies, might represent an important antithrombotic mechanism. Our data indicate that the combination of different polyphenols, as in grape extracts, is much more efficient than the single constituents, a finding that might be useful as starting point for the development of new antithrombotic nutraceutics. In addition, our study validated a simple, inexpensive, and physiologically relevant in vitro

  6. Editorial

    NASA Astrophysics Data System (ADS)

    Bisogni, Maria Giuseppina; Grassi, Marco; Incagli, Marco; Paoletti, Riccardo; Signorelli, Giovanni

    2016-07-01

    The 13th edition of Frontier Detectors for Frontier Physics was held in La Biodola, Isola d'Elba, Italy, on May 24-30, 2015. In 36 years of activity, the Pisa Meeting on Advanced Detectors became a traditional gathering event for people involved in the design, construction and operation of particle detectors all over the world. The number of participants has been steadily increasing from about 100 of the first (1980) edition to more than 300. In parallel the Conference topics followed the trends of the field, in fact detectors and techniques originally developed for High Energy Physics experiments are now used in astro-particle physics, medical physics, archeological research and in countless, different fields.

  7. Tectono-sedimentary evolution and new sections across the western Gran Sasso d'Italia (Central Apennines)

    NASA Astrophysics Data System (ADS)

    Cardello, Giovanni Luca; Bernoulli, Daniel; Doglioni, Carlo

    2010-05-01

    During Jurassic-Cretaceous times, the area of the central Apennines was part of a large, Bahamian-type carbonate platform-basin system, whereby the area of the Gran Sasso was situated between the carbonate platform of Latium and the Abruzzi in the west and the deep basinal area of Marche-Umbria to the east. This transitional area experienced 1. Early Jurassic rifting of the Adriatic margin, leading to the opening of the Ligurian branch of Tethys; 2. prolonged thermal subsidence of the carbonate-platform slope and base-of-slope in the Jurassic-Cretaceous; 3. decollement along Triassic evaporites, thrusting and folding during the Neogene formation of the arc of Gran Sasso and 4. post-nappe normal faulting persisting to this date. Mapping of the western part of the E-W-trending ridge of the Gran Sasso d'Italia has yielded the following results: 1 - The early Jurassic rifting event led to the segmentation of the platform slope into structural highs (Corno Grande and Acqua San Franco) and basins (Pizzo d'Intermesoli, M. Corvo) as suggested by the pronounced differences in thickness of the early-middle Liassic syn-rift sediments (Corniola Formation). Whereas the Acqua San Franco structural high in the west was buried during the Toarcian, the Corno Grande high in the east persisted throughout Mesozoic times at least into the early Tertiary. The longevity and possible tectonic reactivation of the submarine topography, inherited from early Liassic rifting, persisted way into Jurassic-Middle Miocene as suggested by the pronounced differences in thickness of the Jurassic base-of-slope (Corno Piccolo Formation) and Oligocene to Miocene distal ramp sediments, and sequences punctuated by stratigraphic gaps on the highs. 2 - During the Tertiary orogeny of the Apennines, the inherited Mesozoic structures evolved into N-S trending transfer zones between the individual thrusts and folds over- and underthrusting the more external Laga unit. The axis of the frontal anticline and the

  8. Thermal degradation kinetics of anthocyanins extracted from juçara (Euterpe edulis Martius) and "Italia" grapes (Vitis vinifera L.), and the effect of heating on the antioxidant capacity.

    PubMed

    Peron, D V; Fraga, S; Antelo, F

    2017-10-01

    The effect of temperature on the degradation of anthocyanins in juçara and "Italia" grape extracts was determined between 50 and 90°C. For both species, thermal degradation followed a first-order kinetic model. The decimal reduction time decreased with increasing temperature, and dependence on the thermodegradable factor was lower at higher temperatures. The anthocyanins from juçara degraded more slowly than those extracted from "Italia" grapes. The activation enthalpy and free energy of inactivation indicated an endothermic reaction, not spontaneous degradation, whereas the activation entropy suggested that the transition state has less structural freedom than that of the reactants. The antioxidant capacity of the extracts was reduced when subjected to 90°C heat treatment, however, significant quantities of this bioactive compound still remained. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Color recovery in berries of grape (Vitis vinifera L.) 'Benitaka', a bud sport of 'Italia', is caused by a novel allele at the VvmybA1 locus.

    PubMed

    Azuma, Akifumi; Kobayashi, Shozo; Goto-Yamamoto, Nami; Shiraishi, Mikio; Mitani, Nobuhito; Yakushiji, Hiroshi; Koshita, Yoshiko

    2009-04-01

    Color mutations in grape berry skin are relatively frequent events, and can be easily seen in the vineyard. Both light-red-skinned 'Ruby Okuyama' and more intense and uniform rosy-skinned 'Benitaka' (Vitis vinifera L.) are bud sports of white-skinned 'Italia'. Previously, we reported that 'Ruby Okuyama' was caused by the recovery of VvmybA1 expression, which may have occurred as a result of intra-LTR (long terminal repeat) recombination within a retrotransposon, Gret1. However, the molecular basis of the color recovery in 'Benitaka' has not been elucidated so far. Here, we found that the VvmybA1 locus of 'Benitaka' is heterozygous for the VvmybA1a allele (non-functional) and a novel VvmybA1(BEN) allele, and that VvmybA1(BEN) restored VvmybA1 transcripts. We hypothesized that VvmybA1(BEN) allele was caused by homologous recombination between VvmybA1a and VvmybA3. In addition, the content and composition of anthocyanins in berry skins differed greatly between 'Ruby Okuyama' and 'Benitaka'. The levels of expression of the genes for flavonoid 3',5'-hydroxylase (F3'5'H), O-methyltransferase (OMT), and glutathione-S-transferase (GST) were associated with differences in the anthocyanin content and composition between the two cultivars. Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.

  10. Semi-automatic delimitation of volcanic edifice boundaries: Validation and application to the cinder cones of the Tancitaro-Nueva Italia region (Michoacán-Guanajuato Volcanic Field, Mexico)

    NASA Astrophysics Data System (ADS)

    Di Traglia, Federico; Morelli, Stefano; Casagli, Nicola; Garduño Monroy, Victor Hugo

    2014-08-01

    The shape and size of monogenetic volcanoes are the result of complex evolutions involving the interaction of eruptive activity, structural setting and degradational processes. Morphological studies of cinder cones aim to evaluate volcanic hazard on the Earth and to decipher the origins of various structures on extraterrestrial planets. Efforts have been dedicated so far to the characterization of the cinder cone morphology in a systematic and comparable manner. However, manual delimitation is time-consuming and influenced by the user subjectivity but, on the other hand, automatic boundary delimitation of volcanic terrains can be affected by irregular topography. In this work, the semi-automatic delimitation of volcanic edifice boundaries proposed by Grosse et al. (2009) for stratovolcanoes was tested for the first time over monogenetic cinder cones. The method, based on the integration of the DEM-derived slope and curvature maps, is applied here to the Tancitaro-Nueva Italia region of the Michoacán-Guanajuato Volcanic Field (Mexico), where 309 Plio-Quaternary cinder cones are located. The semiautomatic extraction allowed identification of 137 of the 309 cinder cones of the Tancitaro-Nueva Italia region, recognized by means of the manual extraction. This value corresponds to the 44.3% of the total number of cinder cones. Analysis on vent alignments allowed us to identify NE-SW vent alignments and cone elongations, consistent with a NE-SW σmax and a NW-SE σmin. Constructing a vent intensity map, based on computing the number of vents within a radius r centred on each vent of the data set and choosing r = 5 km, four vent intensity maxima were derived: one is positioned in the NW with respect to the Volcano Tancitaro, one in the NE, one to the S and another vent cluster located at the SE boundary of the studied area. The spacing of centroid of each cluster (24 km) can be related to the thickness of the crust (9-10 km) overlying the magma reservoir.

  11. A multicenter phase III prospective randomized trial of high-dose epirubicin in combination with cyclophosphamide (EC) versus docetaxel followed by EC in node-positive breast cancer. GOIM (Gruppo Oncologico Italia Meridionale) 9902 study.

    PubMed

    Vici, P; Brandi, M; Giotta, F; Foggi, P; Schittulli, F; Di Lauro, L; Gebbia, N; Massidda, B; Filippelli, G; Giannarelli, D; Di Benedetto, A; Mottolese, M; Colucci, G; Lopez, M

    2012-05-01

    The Gruppo Oncologico Italia Meridionale 9902 trial compared four cycles of high-dose epirubicin plus cyclophosphamide (EC) with four cycles of docetaxel (Taxotere, D) followed by four cycles of EC as adjuvant treatment of node-positive breast cancer. Patients were randomly assigned to EC (E 120 mg/m(2), C 600 mg/m(2), arm A) for four cycles or four cycles of D (100 mg/m(2)) followed by four cycles of EC (arm B), both regimens every 21 days. Hormone receptor-positive patients were given hormonal therapy for 5 years. Primary end point was 5-year disease-free survival (DFS). Secondary objectives were overall survival (OS) and safety. There were 750 patients enrolled. With a median follow-up of 64 months, 5-year DFS was 73.4% in both arms, and 5-year OS was 89.5% versus 90.7% in arm A and B [hazard ratio was 0.99 (95% confidence interval for DFS 0.75-1.31; P = 0.95)], respectively. Grade 3-4 toxicity was more common in arm B. This study did not show advantages from the addition of docetaxel to high-dose EC as adjuvant chemotherapy in node-positive breast cancer. The small sample size and low number of DFS events may have limited the ability to observe statistically significant difference between the two arms.

  12. A multicenter phase III prospective randomized trial of high-dose epirubicin in combination with cyclophosphamide (EC) versus docetaxel followed by EC in node-positive breast cancer. GOIM (Gruppo Oncologico Italia Meridionale) 9902 study

    PubMed Central

    Vici, P.; Brandi, M.; Giotta, F.; Foggi, P.; Schittulli, F.; Di Lauro, L.; Gebbia, N.; Massidda, B.; Filippelli, G.; Giannarelli, D.; Di Benedetto, A.; Mottolese, M.; Colucci, G.; Lopez, M.

    2012-01-01

    Background: The Gruppo Oncologico Italia Meridionale 9902 trial compared four cycles of high-dose epirubicin plus cyclophosphamide (EC) with four cycles of docetaxel (Taxotere, D) followed by four cycles of EC as adjuvant treatment of node-positive breast cancer. Patients and methods: Patients were randomly assigned to EC (E 120 mg/m2, C 600 mg/m2, arm A) for four cycles or four cycles of D (100 mg/m2) followed by four cycles of EC (arm B), both regimens every 21 days. Hormone receptor-positive patients were given hormonal therapy for 5 years. Primary end point was 5-year disease-free survival (DFS). Secondary objectives were overall survival (OS) and safety. Results: There were 750 patients enrolled. With a median follow-up of 64 months, 5-year DFS was 73.4% in both arms, and 5-year OS was 89.5% versus 90.7% in arm A and B [hazard ratio was 0.99 (95% confidence interval for DFS 0.75–1.31; P = 0.95)], respectively. Grade 3–4 toxicity was more common in arm B. Conclusions: This study did not show advantages from the addition of docetaxel to high-dose EC as adjuvant chemotherapy in node-positive breast cancer. The small sample size and low number of DFS events may have limited the ability to observe statistically significant difference between the two arms. PMID:21965475

  13. La sopravvivenza dei pazienti oncologici in Italia.

    PubMed

    Coviello, Vincenzo; Buzzoni, Carlotta; Fusco, Mario; Barchielli, Alessandro; Cuccaro, Francesco; De Angelis, Roberta; Giacomin, Adriano; Luminari, Stefano; Randi, Giorgia; Mangone, Lucia

    2017-01-01

    Population-based survival statistics are fundamental to assess the efficacy of services offered to improve cancer patients' prognosis. This study aims to update cancer survival estimates for the Italian population, as well as provide new measures, such as the crude probability of death, which takes into account the possibility of dying from causes other than cancer, and the change in life expectancy after a cancer diagnosis, to properly address various questions. The study includes 1,932,450 cancer cases detected by the Network of Italian Cancer Registries (AIRTUM) from 1994 to 2011 and provides estimates for 38 cancer sites and for allsites cancer. For most common cancers diagnosed from 2005 to 2009, age-standardized 5-year net survival was: colon-rectum - males 65%, females 65%; lung - males 15%, females 19%; breast 87%; prostate 91%. For cancer sites such as stomach, colon, rectum, lung, skin melanoma, breast, cervix, prostate, and kidney, 5-year net survival is consistent between Central and Northern Italy, while it is a few percentage points lower in Southern Italy. Funnel plots expose these differences more in detail by showing the survival estimates in 13 Italian regions. For all sites but skin, 5- and 10-year net survival increased by about 10 percentage points in men and 7 points in women from 1994 to 2011. Specific articles deal with results on solid and haematological malignancies, international comparisons and analysis of time trends of incidence, mortality, and survival in combination for key cancer sites, aiming to interpret overall progress in the control of cancer in Italy.

  14. Seismic slip recorded in tourmaline fault mirrors from Elba Island (Italy)

    NASA Astrophysics Data System (ADS)

    Viti, C.; Brogi, A.; Liotta, D.; Mugnaioli, E.; Spiess, R.; Dini, A.; Zucchi, M.; Vannuccini, G.

    2016-05-01

    This paper reports the first example of fault mirrors developed in an unusual protolith, consisting of tourmaline crystals with interstitial goethite. The deformation mechanisms active in the fault zone have been investigated from the outcrop to the nanoscale, aiming to identify possible traces of frictional heating at seismic slip rate, as observed for other fault mirrors in different protoliths. The investigation revealed the superposition of two main deformational stages. The first was dominated by brittle processes and produced a cataclastic/ultracataclastic principal slip zone, a few mm thick; the second was associated with seismic slip and produced a sharp discontinuity (the principal slip surface) within the cataclastic/ultracataclastic zone. The mirror-like coating, a few microns thick, occurs on the principal slip surface, and is characterized by 1) absence of interstitial goethite; 2) occurrence of truncated tourmaline crystals; 3) highly variable grain size, from 200 μm to 200 nm; 4) tourmaline close packing with interlobate grain boundaries, and 5) tourmaline random crystallographic orientation. Micro and nanostructural investigations indicate the occurrence of thermally-activated processes, involving both interstitial goethite and tourmaline. In particular, close to the principal slip surface, goethite is completely decomposed, and produced an amorphous porous material, with local topotactic recrystallization of hematite. Tourmaline clasts are typically characterized by strongly lobate boundaries, indicative of reaction and partial decomposition at grain boundaries. TEM observations revealed the occurrence of tourmaline nanograins, a few tens of nm in size, characterized by rounded shape and fading amorphous boundaries, that cannot be obtained by brittle processes. Lastly, the peculiar interlobate microstructure of the mirror surface is interpreted as the result of grain boundary recrystallization processes taking place by deformation at high-T conditions. Our results show that tourmaline fault mirrors recorded localized high-T processes triggered by frictional heating and can be therefore considered as reliable traces of ancient earthquakes.

  15. Southern LNG, Inc., Elba Island Terminal, Savannah Georgia Draft Air Quality Permit and PSD Preliminary Determination

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. [Public health care system in the Italia regions.].

    PubMed

    Burgio, Alessandra; Solipaca, Alessandro; Milazzo, Rosario

    2007-01-01

    The National Health Plan 2006-2008 underlines the need to overcome the differences that exist in the health care services of the Italian regions. Because the health care systems are organised differently on the territory, the Regions provide different answers to the health needs of their residents. Therefore, the purpose of this document is that of analysing the characteristics of the Italian public health care system in 2003. While in the first part, the health system is described region by region, in the second part, a cluster analysis is used to describe the local health authorities. The results show that while both the first and second level assistance have become stronger, the centrality of the hospital system has decreased, even though it still occupies a dominant position.

  17. Modelling reactive transport in a phosphogypsum dump, Venezia, Italia

    NASA Astrophysics Data System (ADS)

    Calcara, Massimo; Borgia, Andrea; Cattaneo, Laura; Bartolo, Sergio; Clemente, Gianni; Glauco Amoroso, Carlo; Lo Re, Fabio; Tozzato, Elena

    2013-04-01

    We develop a reactive-transport porous media flow model for a phosphogypsum dump located on the intertidal deposits of the Venetian Lagoon: 1. we construct a complex conceptual and geologic model from field data using the GMS™ graphical user interface; 2. the geological model is mapped onto a rectangular MODFLOW grid; 3. using the TMT2 FORTRAN90 code we translate this grid into the MESH, INCON and GENER input files for the TOUGH2 series of codes; 4. we run TOUGH-REACT to model flow and reactive transport in the dump and the sediments below it. The model includes 3 different dump materials (phosphogypsum, bituminous and hazardous wastes) with the pores saturated by specific fluids. The sediments below the dump are formed by an intertidal sequence of calcareous sands and silts, in addition to clays and organic deposits, all of which are initially saturated with lagoon salty waters. The recharge rain-water dilutes the dump fluids. In turn, the percolates from the dump react with the underlying sediments and the sea water that saturates them. Simulation results have been compared with chemical sampled analyses. In fact, in spite of the simplicity of our model we are able to show how the pH becomes neutral at a short distance below the dump, a fact observed during aquifer monitoring. The spatial and temporal evolution of dissolution and precipitation reactions occur in our model much alike reality. Mobility of some elements, such as divalent iron, are reduced by specific and concurrent conditions of pH from near-neutrality to moderately high values and positive redox potential; opposite conditions favour mobility of potentially toxic metals such as Cr, As Cd and Pb. Vertical movement are predominant. Trend should be therefore heavily influenced by pH and Eh values. If conditions are favourable to mobility, concentration of these substances in the bottom strata could be high. However, simulation suggest that the sediments tend to reduce the transport potential of contaminants.

  18. The next steps in Seti-Italia science and technology

    NASA Astrophysics Data System (ADS)

    Montebugnoli, Stelio; Cosmovici, Cristiano; Monari, Jader; Pluchino, Salvatore; Zoni, Luca; Bartolini, Marco; Orlati, Andrea; Salerno, Emma; Schillirò, Francesco; Pupillo, Giuseppe; Perini, Federico; Bianchi, Germano; Tani, Mattia; Amico, Leonardo

    2010-02-01

    The Italian Medicina Radioastronomy Station (nearby Bologna) is equipped with two antennas: the 32 mt (VLBI) dish and the Northern Cross, a large T-shaped parabolic/cylindrical antenna (30.000 sqm). So far Seti observations have been performed using a SERENDIP IV high resolution spectrometer connected to the VLBI dish in "piggy back" mode configuration. In order to facilitate data interpretation and to introduce innovative methods to search for possible extraterrestrial signals, we are planning to make use of the large UHF Northern Cross transit telescope. Sky observations performed at least within two months, could provide for each day a number of matrices labeled according to the observing sidereal time. The entire set of matrices will be characterized by an averaged spectrum on each row per day. Keeping constant the transit antenna declination, a coherent signal coming from a definite position of the sky, would produce a "flag on" in the same submatrix at the same sidereal time. Detections collected in this way could be considered "confirmed" since they always come from the same region of the sky and are observed regularly. An extremely powerful processing board based on a multi-FPGAs (Field Programmable Gate Array) core was developed and is now under programming. This is conceived to be the processing core for this new kind of investigations.

  19. 76 FR 78638 - Elba Express Company, L.L.C; Notice of Intent To Prepare an Environmental Assessment for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... properties.\\4\\ We will define the project-specific Area of Potential Effects (APE) in consultation with the SHPO as the project develops. On natural gas facility projects, the APE at a minimum encompasses...

  20. 77 FR 45596 - Elba Express Company, L.L.C.; Notice of Availability of the Environmental Assessment for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... libraries in the project area; and parties to these proceedings. In addition, the EA is available for public viewing on the FERC's Web site ( www.ferc.gov ) using the eLibrary link. A limited number of copies of the... comments prior to making its decision on this project, it is important that we receive your comments...

  1. International Workshop on Condensed Matter Theories (14th), Held in Isola d’Elba, Italy on June 18-23, 1990

    DTIC Science & Technology

    1990-06-23

    Monte Carlo methods, or with such physical systems as quantum fluids, finite nuclei and nuclear matter, highly correlated electronic systems, and...gave a nice talk on the application of quantum Monte Carlo (QMC) techniques to the Anderson model, with the incorporation of maximum entropy ideas which...8217 AFSENI INA PRIE1O C. F~5ID A.R. Universidad de Sala~anca Laboratorio de Fisica Cl.E Facultad de C. Fisicas Arlibertador 1513 (1638) 38008 SALAMANCA

  2. Volcanic spreading forcing and feedback in geothermal reservoir development, Amiata Volcano, Italia

    NASA Astrophysics Data System (ADS)

    Borgia, Andrea; Mazzoldi, Alberto; Brunori, Carlo Alberto; Allocca, Carmine; Delcroix, Carlo; Micheli, Luigi; Vercellino, Alberto; Grieco, Giovanni

    2014-09-01

    We made a stratigraphic, structural and morphologic study of the Amiata Volcano in Italy. We find that the edifice is dissected by intersecting grabens that accommodate the collapse of the higher sectors of the volcano. In turn, a number of compressive structures and diapirs exist around the margin of the volcano. These structures create an angular drainage pattern, with stream damming and captures, and a set of lakes within and around the volcano. We interpret these structures as the result of volcanic spreading of Amiata on its weak substratum, formed by the late Triassic evaporites (Burano Anhydrites) and the Middle-Jurassic to Early-Cretaceous clayey chaotic complexes (Ligurian Complex). Regional doming created a slope in the basement facilitating the outward flow and spreading of the ductile layers forced by the volcanic load. We model the dynamics of spreading with a scaled lubrication approximation of the Navier Stokes equations, and numerically study a set of solutions. In the model we include simple functions for volcanic deposition and surface erosion that change the topography over time. Scaling indicates that spreading at Amiata could still be active. The numerical solution shows that, as the central part of the edifice sinks into the weak basement, diapiric structures of the underlying formations form around the base of the volcano. Deposition of volcanic rocks within the volcano and surface erosion away from it both enhance spreading. In addition, a sloping basement may constitute a trigger for spreading and formation of trains of adjacent diapirs. As a feedback, the hot hydrothermal fluids decrease the shear strength of the anhydrites facilitating the spreading process. Finally, we observe that volcanic spreading has created ideal heat traps that constitute todays' exploited geothermal fields at Amiata. Normal faults generated by volcanic spreading, volcanic conduits, and direct contact between volcanic rocks (which host an extensive fresh-water aquifer) and the rocks of the geothermal field, constitute ideal pathways for water recharge during vapour extraction for geothermal energy production. We think that volcanic spreading could maintain faults in a critically stressed state, facilitating the occurrence of induced and triggered seismicity.

  3. [Stima dei decessi per tumori attribuibili a fattori di rischio comportamentali in Italia nel 2013].

    PubMed

    Battisti, Francesca; Carreras, Giulia; Grassi, Tommaso; Chellini, Elisabetta; Gorini, Giuseppe

    2017-01-01

    "Non-communicable diseases cause more than 80% of deaths in europe and, among these, 20% are caused by cancer. Modifiable lifestyle factors considered in the italian national programme "Guadagnare salute" (Gaining health), such as tobacco smoking, unhealthy diet, physical inactivity, overweight, and excessive alcohol use, are amongst the major causes of cancer deaths. The aims of this study was to estimate the number of deaths attributable to lifestyle factors for italy and for italian regions in 2013 and to describe its variation in relation to the regional prevalence of risk factors exposure. For Italy and for each italian region, deaths attributable to lifestyle factors were estimated using the methodology of the Global Burden of disease (GBd) study. italian mortality data of 2013 and risks attributable to these lifestyle factors for each cancer site for italy from the GBd study were used. Prevalence of exposure to lifestyles in Italy and in each Italian Region was collected for the period 2008-2013. In 2013, at least 66,605 cancer deaths in italy were attributable to lifestyle factors, accounting for 37.9% of all cancer deaths: 34.1% of cancer deaths in men and 9.0% in women were attributable to smoking; in men and women, respectively, 3.3% and 2.8% were attributable to excessive alcohol consumption; 5.3 % and 6.7% to overweight; 10.1% and 7.1% to dietary risk factors; 1.9% and 4.2% to physical inactivity. A moderate variability of percentage of deaths attributable to modifi able lifestyle factors by region was also detected due to different prevalence values of exposure to lifestyles occurred in last decades. At least 45,000 cancer deaths in men and 21,000 in women occurred in 2013 were attributable to modifi able risk factors, whose prevalence varied by region and which could be averted through the implementation of primary prevention interventions."

  4. Italia-Netherland PhD Program: the I.O. PhD Research Program.

    PubMed

    Bellissima, Valentina; Borghesi, Alessandro; Bozzetti, Valentina; Dessì, Angelica; Fabiano, Adele; Risso, Francesco M; Salvo, Vincenzo; Satriano, Angela; Silvagni, Davide; Varrica, Alessandro; van Bel, Frank; Visser, Gerard H A; Vles, Hans Js; Zimmermann, Luc J I; Gavilanes, Antonio D W; Gazzolo, Diego

    2011-10-01

    In the framework of long-term scientific collaboration among the founder members coming from Holland and Italy there was a growing consensus to activate a philosophical doctorate (PhD) program, involving young Italian researchers in the field of perinatal medicine, neonatology and pediatrics. The aims were to promote excellence in research, offering to young Italian physicians the opportunity to maturate an International research experience leading to PhD degree, and to promote human and technological improvement energies in perinatal, neonatal and pediatrics research. Thus, an official collaboration among the Dutch Universities from Maastricht and Utrecht and the Italian Children's Hospital from Alessandria, has been activated on March 1st 2010, finalized to the PhD program. The experimental phase included the selection of projects and relative candidates after an interview-selection focusing on their scientific attitudes and the availability on their research projects. Candidates' selection started on May 2010 and on September 29th ten projects and candidates have been approved by the scientific commission. Research topics included: perinatal asphyxia, aging and the origin of adulthood neurodegenerative disease, neuroprotective strategies, biochemical pulmonology, intrauterine growth retardation and perinatal teratology. To date, all projects have been approved by local Ethics Committee from the University/Hospital of origin of the candidates. Five manuscripts have been published and/or submitted to international Journals regarding pneumology, perinatal asphyxia and teratology, whilst about 60-70% of data regarding clinical studies have already been collected.

  5. Faults strengthening and seismicity induced by geothermal exploitation on a spreading volcano, Mt. Amiata, Italia

    NASA Astrophysics Data System (ADS)

    Mazzoldi, Alberto; Borgia, Andrea; Ripepe, Maurizio; Marchetti, Emanuele; Ulivieri, Giacomo; Schiava, Massimo della; Allocca, Carmine

    2015-08-01

    Seismogenic structures such as faults play a primary role in geothermal system generation, recharge and output. They are also the most susceptible to release seismic energy over fluid injection/extraction operations during anthropic exploitation. We describe the microseismic activity recorded in 2000-2001 in the Piancastagnaio geothermal field, on the SE flank of Mt. Amiata volcano, southern Tuscany, Italy. From our field observations we find that a relatively high percentage (i.e. about 5%) of the recorded events are of hydro-fracturing origin and have a distinct waveform seismic signature when compared to the recorded events of tectonic shear-fracturing origin. While hydrofracturing events are mostly concentrated around the geothermal fields, the spatial distribution of hypocenters shows a deepening and a density increase of the micro-seismic activity from the volcanic axis toward the exploited geothermal reservoir, suggesting that volcanic spreading at Amiata is still active. The study of different data-sets from different time periods together with the knowledge from Terzaghi's law that production of large quantity of pore-fluid with the associated fluid pressure reduction could augment the stress normal to faults' surfaces (and thus their resistance to slip), make us argue that the process of volcanic spreading affecting the edifice of Amiata may allow augmented accumulation of stresses on faults, eventually leading to the release of higher stress drops, once ruptures occur. The Gutenberg-Richter magnitude-frequency distribution shows that the strongest events on record have a local magnitude in the 5-5.5 ML range, for 100-year recurrence time. In conclusions, we infer that geothermal exploitation at Mt. Amiata should be closely monitored in order to understand how fluid injection/production is responsible for the hydrofracturing seismic activity and affects stress accumulation on and rupture of faults within and in the neighborhood of the geothermal fields. This understanding may allow a geothermal field management that will hopefully reduce the risk for inducing larger seismic events in the area.

  6. [Hand-arm vibration syndrome and upper limbs diseases in the forest workers of Italia meridionale].

    PubMed

    Fenga, C; Rapisarda, V; Valentino, M; Cacciola, A; Deboli, R; Calvo, A; Germanò, D

    2007-01-01

    Vibration exposure of the hand-arm system is associated with an increased risk of upper-limb vascular, neurological and musculoskeletal lesions, or hand-arm vibration syndrome (HAVS). The prevalence of occupational HAVS and upper-limb disorders was studied among 278 Forestry Service workers in Sicily and Calabria. Subjects who used chain-saws (18 weeks/year) had a greater prevalence of peripheral sensory-neural disturbances (28%), upper-limb musculoskeletal disorders (33%) and carpal tunnel syndrome (19%) compared with 260 manual workers from the same Corps not exposed to hand-transmitted vibration. Raynaud's phenomenon was comparable in exposed and control subjects (5.3% vs. 4.7%.) Upper-limb neuropathies were significantly associated with energy-equivalent frequency-weighted acceleration; exposure duration; and cumulative vibration dose (m2/s4h). The variable "years of work with vibrating tools" was strongly associated with peripheral neuropathies; carpal tunnel syndrome; and upper-limb musculotendinous syndromes. Data suggest that in Sicily and Calabria, where the climate is milder than in other areas of Italy, forestry work with hand-held vibrating tools does not entail a greater prevalence of peripheral vascular disorders (Raynaud's phenomenon), while the prevalence of occupational upper-limb neurological and musculoskeletal disorders, in which combined ergonomic and mechanical risk factors have a large pathogenic role, is significantly increased.

  7. Hermann Oberth in Italia: "Roba da bambini". (English Title: Hermann Oberth in Italy: "Kid stuff")

    NASA Astrophysics Data System (ADS)

    Balestrieri, R.

    2017-10-01

    After the Second World War, Italy sought to equip itself with surface-to-air missiles: first with its own projects, then acquiring equipment already developed by the USA. The LAGO Project of the Marina Militare was born for defensive purposes: it was defined with Hermann Oberth in 1950 and was developed in La Spezia from 1951 to 1953.

  8. SETI-ITALIA 2008: On-going searches and future prospects

    NASA Astrophysics Data System (ADS)

    Montebugnoli, S.; Bartolini, M.; Bianchi, G.; Cosmovici, C.; Monari, J.; Orlati, A.; Perini, F.; Pluchino, S.; Pupillo, G.; Salerno, E.; Schillirò, F.; Zoni, L.

    2010-12-01

    The Medicina Radioastronomical Station is located nearby Bologna, in Italy. It consists of two receiving antennas currently dedicated to the astronomical research at radio frequencies. The 32 m diameter parabolic dish performs observations from 1.4 to 22 GHz whereas the Northern Cross (a 30.000 m 2 wide T-shaped array transit antenna) works at 408 MHz. So far SETI observations have been performed using a SERENDIP IV high resolution spectrometer connected to the parabolic antenna. Data acquisition were performed meanwhile the antenna was employed in ordinary astronomical observations (piggy-back mode). An innovative method to search for possible extraterrestrial signals could be provided by using the UHF Northern Cross transit telescope. In this paper observational modalities and the required technological set-up are investigated.

  9. Integrated Call Design: "Crescendo in Italia," a Language Teaching Package for Intermediate Italian Learners.

    ERIC Educational Resources Information Center

    Brussino, Gabriella; Luciano, Bernadette; Gunn, Cathy

    1999-01-01

    Presents the theoretical principles, integration, and final evaluation of a multimedia program tailored for an intermediate Italian language course. The program, designed as a metaphorical journey, contextualizes the themes of the course while bringing the student into contact with real Italian cities and people. Provides a sociocultural context…

  10. New paleoseismological data from the Gran Sasso d'Italia area (central Apennines)

    NASA Astrophysics Data System (ADS)

    Galli, P.; Galadini, F.; Moro, M.; Giraudi, C.

    2002-04-01

    Paleoseismological analyses along the Campo Imperatore normal fault (CIF) in the Gran Sasso massif, which is an area characterized by the absence of significant historical earthquakes, highlight the occurrence of surface faulting after the 5th-3rd cent. BC and around the 6th-5th millenium BC. These ages agree with those reported by Giraudi and Frezzotti [1995] on the western tip of the CIF, thus suggesting the possible entire rupture of the 30-km-long CIF during M~7 events. These data contribute to the re-evaluation of the seismic hazard of a large surrounding area, including the city of L'Aquila (~100.000 inhabitants), which is located 20 km from the CIF, in the hangingwall side.

  11. Impariamo Insieme in Italia (Learning Together in Italy) via "Scambio Di Instruzione--Through Instructional Exchange"

    ERIC Educational Resources Information Center

    Veltri, Barbara Torre

    2015-01-01

    Preparing teacher candidates for their roles in 21st century schools calls for direct experiences with inquisitive, linguistically diverse, and often technologically savvy students across global and economic contexts. This article presents the lessons learned from a practicum experience during a semester abroad in Italy, where faculty, teacher…

  12. Measuring the efficacy of advertising communication with neuroscience methods: an experiment performed by Telecom Italia.

    PubMed

    Grimaldi, Loredana

    2012-01-01

    Recently, there has been a concentrated effort by companies to better understand the needs and desires of their consumers. Such efforts usually employ different and sophisticated analysis techniques for monitoring the consumers preferences and how such consumers perceive the advertising communication campaign from a specific company.

  13. La Carta Mentale D"Italia in Alunni Di Scuola Media.

    ERIC Educational Resources Information Center

    Genzo, Carlo

    1992-01-01

    Shows and discusses the results of a test on the "mental representations" of Italy in pupils (11-14 years) living in different Italian towns. The results reveal some common psycho-special features that are independent of the dwelling localities. (Author)

  14. Integrated Call Design: "Crescendo in Italia," a Language Teaching Package for Intermediate Italian Learners.

    ERIC Educational Resources Information Center

    Brussino, Gabriella; Luciano, Bernadette; Gunn, Cathy

    1999-01-01

    Presents the theoretical principles, integration, and final evaluation of a multimedia program tailored for an intermediate Italian language course. The program, designed as a metaphorical journey, contextualizes the themes of the course while bringing the student into contact with real Italian cities and people. Provides a sociocultural context…

  15. La Carta Mentale D"Italia in Alunni Di Scuola Media.

    ERIC Educational Resources Information Center

    Genzo, Carlo

    1992-01-01

    Shows and discusses the results of a test on the "mental representations" of Italy in pupils (11-14 years) living in different Italian towns. The results reveal some common psycho-special features that are independent of the dwelling localities. (Author)

  16. Strategies to Improve Medication Adherence in Older Persons: Consensus Statement from the Senior Italia Federanziani Advisory Board.

    PubMed

    Marengoni, Alessandra; Monaco, Alessandro; Costa, Elisio; Cherubini, Antonio; Prados-Torres, Alexandra; Muth, Christiane; Melis, Renè J F; Pasina, Luca; van der Cammen, Tischa J M; Palmer, Katie; Pecorelli, Sergio; Onder, Graziano

    2016-09-01

    Poor adherence to treatment regimens has long been recognized as a substantial roadblock to achieving better outcomes for patients. Non-adherence to medications affects the quality and length of life and has been associated with negative health outcomes and increasing healthcare costs. The problem of non-adherence is particularly troublesome in older patients who are affected by multiple chronic diseases and for this reason receive multiple treatments. To date, no single intervention strategy has been shown to be effective in improving adherence across all patients, conditions, and settings. Between September and October 2014, a group of experts in geriatrics, pharmacology, epidemiology, and public health applied a modified RAND appropriateness method to reach a consensus on the possible best interventions to improve adherence in older individuals. Seven interventions were identified, classified based on their target (patient, therapy, and public health/society): (1) Comprehensive Geriatric Assessment, (2) patient (and caregiver) education to improve patient empowerment, (3) optimization of treatment, (4) use of adherence aids, (5) physician and other healthcare professionals' education, (6) adherence assessment, (7) facilitating access to medicine by service integration. For each intervention, experts assessed (a) target population, (b) health professionals potentially involved in the intervention, (c) strategies/instruments needed for implementation, and (d) time of the intervention. Interventions that target adherence must combine different approaches targeting the complex aspects of older adults in a holistic approach. Tackling non-adherence, with its complexity, requires a multi-stakeholder patient-centred approach acting in a defined framework of interactions in which the different players may provide different services but are integrated with one another.

  17. Polyphenol content in white table grape (Vitis Vinifera) berries of cultivar Italia: interactive effect of irrigation, delayed harvest and storage.

    PubMed

    Capriotti, Anna Laura; Caruso, Giuseppe; Cavaliere, Chiara; Foglia, Patrizia; Laganà, Aldo; Samperi, Roberto

    2012-01-01

    Polyphenol concentrations were quantified by rapid resolution liquid chromatography/mass spectrometry in white table grape. The experimental vineyard was subjected to different kinds of water supply and supply rates. Samples from the same vineyards were also analysed after 6 weeks of storage in a refrigerator and after 6 weeks of delayed harvesting. Berry skins and seeds were analysed separately. A statistical treatment of the screening kind, namely the 2(k) full factorial design, was used for the interpretation of results. Storage, delayed harvesting and the different kinds of water supply appeared to be the variables most affecting grape polyphenol content. In some cases, results showed that polyphenol content diminished by more than 50% after 6 weeks if the grapes were stored in a refrigerator, or if a sprinkler was used for irrigation.

  18. Check on level of environmental contamination by mercury and cleanup of Abetina Mining area (Grosseto-Italia)

    SciTech Connect

    Belardi, G.; Marabini, A.M.; Passariello, B.

    1996-12-31

    The purpose of the study was to check on the level of environmental contamination and to design a project for cleaning up the Abetina Mine area at Piancastagnaio (Grosseto, Italy). Contamination of this area had occurred during the mining and treatment of cinnabar (HgS) over a prolonged period. The aim of the project is to remove the sources of contamination or render them harmless. Mining of the Piancastagnaio deposit started in 1840, mercury metal being extracted from the ore by thermal treatment. Together with Spain, Italy was the first country to produce this metal and was the world leader in this field between 1936 and 1943. Though mercury production in the Monte Amiata region of Tuscany ceased in 1974 the ensuing environmental impact is very evident, taking the form of rusty old mining and processing works, plus waste tips which still contain considerable amount of mercury even after the ore had been subject to thermal extraction treatment. The research which has been conducted included mapping the area to identify the main sources of mercury and arsenic pollution, as well as the level of environmental contamination. Mercury and arsenic values in excess of 16,000 and 150 ppm respectively are encountered in the most highly-contaminated places. 11 refs., 6 figs., 2 tabs.

  19. Irinotecan plus bolus/infusional 5-Fluorouracil and leucovorin in patients with pretreated advanced pancreatic carcinoma: a multicenter experience of the Gruppo Oncologico Italia Meridionale.

    PubMed

    Gebbia, Vittorio; Maiello, Evaristo; Giuliani, Francesco; Borsellino, Nicolò; Arcara, Carlo; Colucci, Giuseppe

    2010-10-01

    Patients with advanced pancreatic cancer failing gemcitabine-based first-line chemotherapy are still in relatively good clinical conditions and may still require second-line chemotherapy, which is frequently administered in daily clinical practice given to without solid scientific support. A retrospective survey was carried out including 40 patients with stage III or IV gemcitabine-refractory pancreatic carcinoma. Patients received standard FOLFIRI regimen biweekly until progression or unacceptable toxicity. Response evaluation criteria in solid tumors and National Cancer Institute common toxicity criteria were employed respectively for response and toxicity assessment. Six partial responses (15%) and 14 stabilizations of disease (35%) were recorded for a tumor growth control rate of 50%. The median time to progression was 3.7 (range, 1-6.5 months), and median overall survival was 6 months (range, 2-8.2 months). A stabilization of performance status and a subjective improvement of cancer-related symptoms were recorded in 21 patients (52.5%). No correlation has been found between length of time to progression during first-line chemotherapy and length of that reported in the second-line setting or objective response. Grade 3-4 diarrhea and mucositis was observed in 15% and 10% of cases, respectively. Data presented in this article demonstrate that the second-line FOLFIRI regimen are able to induce an objective response in a relatively small fraction of patients with gemcitabine-refractory adenocarcinoma of the pancreas. The use of second-line chemotherapy should be carefully proposed to patients with good performance status or those who had a good response to first-line therapy.

  20. Mutual Phenomena between Galilean Satellites: PHEMU09 Campaign in Italy. (Italian Title: Occultazioni ed eclissi tra i satelliti medicei: i risultati della campagna PHEMU09 in Italia)

    NASA Astrophysics Data System (ADS)

    Marino, G.; Arena, C.; Barbieri, L.; Lopresti, C.; Lo Savio, E.; Marchini, A.; Masi, G.; Maulella, R.; Napoli, C.; Salvaggio, F.; Sbarufatti, G.; Sciuto, C.; Ruocco, N.; Ruisi, R.; Sofia, A.; Tontodonati, E.; Zambelli, R.

    2011-06-01

    Results of photometry of mutual phenomena between Galilean satellites are presented. The observations were performed in Italy during the international campaign PHEMU09.Relevant deviations (O-C) with respect to the expected central instants are present for many events. Taking into account the relative satellites’ longitudinal velocity, longitudinal discrepancies in km (and arcsec) are also computed. The discrepancies with respect to the expected flux drops during the occultations are apparently uncorrelated with the O-C on timing (and longitudinal deviations in km); moreover, for eclipses they seem greater than for occultations

  1. Screening of older community-dwelling people at risk for death and hospitalization: the Assistenza Socio-Sanitaria in Italia project.

    PubMed

    Mazzaglia, Giampiero; Roti, Lorenzo; Corsini, Giacomo; Colombini, Angela; Maciocco, Gavino; Marchionni, Niccolò; Buiatti, Eva; Ferrucci, Luigi; Di Bari, Mauro

    2007-12-01

    To develop and validate mortality and hospitalization prognostic tools based upon information readily available to primary care physicians (PCPs). Population-based cohort study. Baseline predictors were patient demographics, a seven-item questionnaire on functional status and general health, use of five or more drugs, and previous hospitalization. Community-based study. Prognostic indexes were developed in 2,470 subjects and validated in 2,926 subjects, all community-dwelling, aged 65 and older, and randomly sampled from the rosters of 98 PCPs in Florence, Italy. Fifteen-month mortality and hospitalization. Two scores were derived from logistic regression models and used to stratify participants into four groups. With Model 1, based upon the seven-item questionnaire, mortality rate ranged from 0.8% in the lowest-risk group (0-1 point) to 9.4% in the highest risk group (> or = 3 points), and hospitalization rate ranged from 12.4% to 29.3%; area under the receiver operating characteristic curves (AUC) was 0.75 and 0.60, respectively. With Model 2, considering also drug use and previous hospitalization, mortality and hospitalization rates ranged from 0.3% to 8.2% and from 8.1% to 29.7%, for the lowest-risk to the highest-risk group; the AUC increased significantly only for hospitalization (0.67). Prediction of death and hospitalization in older community-dwelling people can be easily obtained with two indexes using information promptly available to PCPs. These tools might be useful for guiding clinical care and targeting interventions to reduce the need for hospital care in older persons.

  2. [Biology, thermal requirements and fertility life table of the broad mite Polyphagotarsonemus latus (Banks) (Acari: Tarsonemidae) in grape (Vitis vinifera L.) cv. Italia].

    PubMed

    Ferreira, Rodrigo C F; de Oliveira, José V; Haji, Francisca N P; Gondim, Manoel G C

    2006-01-01

    The mite Polyphagotarsonemus latus (Banks) constitutes one of the main pest of grape crop at the Submédio São Francisco Valley. The objective of this work was to study the biology of the broad mite Polyphagotarsonemus latus (Banks), to determine its thermal requirements and its fertility life table in grape (Vitis vinifera L.) cv. Italy. Acclimatized chambers (BOD) were used, adjusted to the temperatures of 18, 22, 25, 28 and 32 degrees C, relative humidity of 65 +/- 10% and alternated light of 12h. Egg-adult period was 3.4 and 6.8 days for males and 3.5 and 7.4 days for females, respectively at 32 degrees C and 18 degrees C. At the temperatures of 18, 25 and 32 degrees C, each female deposited, respectively, 16.5, 44.3 and 13.3 eggs. The stages of egg, larva and pupa and egg-adult period presented, respectively, thermal thresholds of 11.23, 9.45, 12.19, and 9.71 degrees C and thermal constant of 28.51, 14.59, 8.33, and 62.73 degrees-day. The mean duration of one generation (T) was 25.6, 10.8 and 8.2 days, respectively, at the temperatures of 18, 25 and 32 degrees C. The net reproductive rate (R0) at the temperature of 25 degrees C was the highest, corresponding to an increase of 30.12 times at each generation. The intrinsic rate of population increase (rm) was 0.10 (18 degrees C), 0.31 (25 degrees C) and 0.12 (32 degrees C) and the finite ratio of population increase (lambda) was 1.10 (18 degrees C), 1.36 (25 degrees C) and 1.13 (32 degrees C). According to the mean temperature values, P. latus can have 95 and 99 generations/year, respectively, for the municipal districts of Petrolina, PE and Juazeiro, BA.

  3. [Gender differences of at risk patients with overt heart failure in the real world of general practice. Data from the GIPSI (Gestione Integrata Progetto Scompenso in Italia) registry].

    PubMed

    Gronda, Edoardo; Aronica, Alberto; Visconti, Marco; Di Malta, Antonio; Pini, Daniela; Mangiavacchi, Maurizio; Andreuzzi, Bruno; Municinò, Annamaria; Genovese, Stefano; Morenghi, Emanuela

    2010-03-01

    Controlled clinical trials have defined the characteristics of specialized world populations, different from the real world population. On this basis, the GIPSI registry was created, aiming to collect data from heart failure populations managed by general practitioners, focusing on gender differences. The registry was based on family history, clinical and laboratory data collection from general practitioners. Patients were considered as being at risk for heart failure if data applied to stage A/B, or presenting overt heart failure if data applied to stage C/D of the American College of Cardiology/American Heart Association classification. From June 2006 to October 2007, 757 consecutive patients (475 male, 62.7%) were enrolled from 260 general practitioner's practices; 227 patients (143 male, 63.0%) had overt heart failure. In the female population at risk, higher systolic and diastolic blood pressure values were observed, whereas males showed more frequently ischemic heart disease, hypercholesterolemia and hypertriglyceridemia, and were more often prescribed with statins and antiplatelet drugs. There were more heart failure females with diabetes and of advanced age. Moreover, females showed a higher pulse pressure and a significantly lower estimated glomerular filtration rate (by simplified MDRD equation) than males. The data collected in a real world population show that heart failure has significantly different gender characteristics, especially for risk factors, age, blood pressure and renal function. This kind of investigation should be extended to larger patient populations for a better understanding of the disease.

  4. Comparison between mechanisms of CO2 degassing from El Chichon volcanic lake, México, and Specchio di Venere lake, Pantelleria, Italia.

    NASA Astrophysics Data System (ADS)

    Jácome Paz, M. P.; Taran, Y.; Inguaggiato, S.; Collard, N.; Vita, F.; Pecoraino, G.

    2014-12-01

    We present results of the CO2 diffuse emission from the surface of two volcanic lakes: El Chichón (EC) in Mexico and Specchio di Venere (SV) on Pantelleria Island, Italy. Both lakes are drainless, have similar sizes (~2x105 m2) and similar input-output dynamics. However, they are drastically different in water chemistry. The SV lake is alkaline (pH >9) and of a high near constant salinity, whereas EC lake is acidic (pH 2.3) and of a low variable salinity. In the vicinity of both lakes there are thermal grounds with steam vents and hot springs and a high CO2 soil flux. The SV lake has high alkalinity (~70 meq/L), whereas the EC lake is characterized by high concentration of dissolved CO2. CO2 flux measurements from the surface of both lakes were made with the "floating" accumulation chamber. During the flux measuring, gas samples were taken for carbon isotopic analysis. Soil flux measurements were also made in the crater of El Chichon volcano and on the area adjacent to the SV lake. The preliminary results of CO2 fluxes indicate EC lake has a high CO2 flux with a mean value of 3500 g m-2 d-1, with the highest values alignment across NW-SE and NE-SW faults and a high degassing by bubbling gases, especially near the strongest NE fumarolic field. While SV has a mean value of the CO2 flux ~ 10 g m-2 d-1 and limited bubbling on the lake surface. High CO2 flux was measured from the soil near the lake at the Mofeta place. A net mean diffusion flux (without bubbles) from EC lake is about 350 times higher than that from SV lake (3500 g m-2 d-1 vs 10 g m-2 d-1). SV has the total CO2 flux by diffusion of ~3 ton d-1 from an area of 0.3 km2 and the total flux of 0.44 ton d-1 by bubbling areas at SW and S zones. The EC lake has the total CO2 flux of 840 ton d-1 from an area of 0.24 km2. The total CO2 output from SV is nevertheless about two times higher taking into account the seepage from the lake (~ 8 kg s-1) of highly carbonated water.

  5. [La percezione del rapporto ambiente-salute secondo i dati della sorveglianza Progressi delle aziende sanitarie per la salute in Italia (PASSI)].

    PubMed

    Sampaolo, Letizia; Tommaso, Giulia; Gherardi, Bianca; Carrozzi, Giuliano; Freni Sterrantino, Anna; Ottone, Marta; Goldoni, Carlo Alberto; Bertozzi, Nicoletta; Scaringi, Meri; Bolognesi, Lara; Masocco, Maria; Salmaso, Stefania; Lauriola, Paolo

    2017-01-01

    "OBJECTIVES: to identify groups of people in relation to the perception of environmental risk and to assess the main characteristics using data collected in the environmental module of the surveillance network Italian Behavioral Risk Factor Surveillance System (PASSI). perceptive profiles were identified using a latent class analysis; later they were included as outcome in multinomial logistic regression models to assess the association between environmental risk perception and demographic, health, socio-economic and behavioural variables. the latent class analysis allowed to split the sample in "worried", "indifferent", and "positive" people. The multinomial logistic regression model showed that the "worried" profile typically includes people of Italian nationality, living in highly urbanized areas, with a high level of education, and with economic difficulties; they pay special attention to their own health and fitness, but they have a negative perception of their own psychophysical state. the application of advanced statistical analysis enable to appraise PASSI data in order to characterize the perception of environmental risk, making the planning of interventions related to risk communication possible. ".

  6. Origin and evolution of sinkholes in an alluvial setting: the case study of Piano dell'Acqua (San Basile, Northern Calabria, Italia)

    NASA Astrophysics Data System (ADS)

    Iovine, Giulio G. R.; Parise, Mario; Caloiero, Tommaso; Ferraro, Giuseppe; Lanza, Giuseppe; Nicolino, Nicola; Suriano, Stefania

    2010-05-01

    Five sinkholes have recently been identified at "Piano dell'Acqua", in the territory of San Basile (Northern Calabria, Southern Italy). They are located in a hilly setting, where the main landform is represented by a slight valley draining toward the east. The sinkholes are limited in size, with maximum diameter of 10 m, and maximum depth of 2.5 m. Two of them present elongated shapes, whilst the remaining three are circular. The area where the sinkholes developed is characterized by Pliocene conglomerate and sand, dislocated by tectonic lines. Sinkhole phenomena were initially investigated in the whole territory by means of multi-temporal aerial photos; the outcomes from this analysis were checked in the field through geological, structural and geomorphological surveys. Historical analysis was started in order to collect and critically evaluate the existing information and testimonies about the age of occurrence of the surveyed phenomena; several interviews with local inhabitants were performed, and a number of archives scrutinized. As a result, it may be assumed that two out of the five identified sinkholes developed during the winter 2000-2001 (period "a"), with likely rapid formation; two of the other cases probably originated during the 70's (period "b"), as also suggested by the age of the vegetation hosted within the sinkholes; c) the last sinkhole opened sometime between February 2001 and November 2007 (period "c"). According to the collected testimonies, a further phase of sinkhole development might have occurred in the first half of the past Centruty, but no field evidence of this older phase has been found. Analysis of the seismic catalogues showed that no earthquake can be identified as possible trigger of any of the sinkholes at Piano dell'Acqua. Therefore, the origin of the studied phenomena may be related to sub-cutaneous erosion, within an area that is rich in groundwater. Local changes in the water table, both related to climate and man-induced activities, may have triggered the development of the sinkholes that, according to the sinkholes' classification by Waltham and co-workers (2005), belong to the "suffusion" or "dropout" types. The local stratigraphic and tectonic conditions at Piano dell'Acqua have been investigated through Electrical Resistivity Tomography, aiming at also identifying unknown underground cavities which may be hydraulically connected with the superficial features. Moreover, hydrologic investigations have been carried out in order to analyse in detail the climatic conditions of the three periods (a-c) mentioned above. Recorded rainfalls and drought periods have been analysed by means of the Standardized Precipitation Index, by computing the deficit of precipitation for different temporal scales. By applying the method of the runs, the return periods of the drought periods have also been evaluated. Thanks to the performed analyses, the geological characteristics of the study area and the climatic characteristics of the assumed periods (a-c) of origin of the sinkholes have been investigated in detail, and a progressive shortening of the return periods of origin of the sinkholes could be pointed out.

  7. Oral vinorelbine plus capecitabine (oral vincap) combination in patients with advanced breast cancer (ABC). A phase II study of the GOIM (Gruppo Oncologico dell'Italia Meridionale).

    PubMed

    Lorusso, V; Spada, M; Giampaglia, M; Misino, A; Calabrese, R; Latorre, A; Monticelli, G; Guida, M; Sambiasi, D; Colucci, G

    2006-06-01

    Vinorelbine i.v. and capecitabine are two of the most effective single agents in previously treated advanced breast cancer (ABC). A number of studies have been reported with the combination of these agents. Actually, the availability of oral formulation for vinorelbine allows a full oral combination of the two agents. The aim of this study was to evaluate the activity and toxicity of this novel combination. Thirty-eight advanced breast cancer patients refractory to anthracyclines and taxanes were included in this study. Treatment consisted of vinorelbine 60 mg/m(2) (days 1 + 8), and capecitabine 2000 mg/m(2) (days 2-7 and 9-16) every 3 weeks. A total of 228 courses were given with a mean of three cycles/patient (range 1-12). Five patients (13.1%) had no toxicity at all. Hematologic side-effects were: neutropenia grade 2-3 in seven patients (18.9%) and grade 4 in one patient (2.7%), anemia grade 1 in 11 patients (29.7%), grade 2-3 in five patients (13.5%), thrombocytopenia grade 1 in six patients (16.2%) and grade 3 in one patient (2.7%). Non-hematologic side-effects were: fatigue grade 1 in five patients (13.5%), hand-foot syndrome grade 1 in two patients (5.4%) and grade 2 in two patients (5.4%), nausea/vomiting grade 1 in two patients (5.4%), grade 2 in three patients (8.1%) and grade 3 in one patient (2.7%), constipation grade 1 in two patients (5.4%), peripheral neurotoxicity grade 1 in three patients (8.1%) and grade 2 in one patient (2.7%), gastric pain grade 1 in two patients (5.4%), stomatitis grade 1 in three patients (8.1%) and grade 2 in one patient (2.7%). Out of 38 patients assessable, we observed two (5.4%) CR, 13 (34 %) PR, 14 (37.8%) SD and nine (26.3%) PD. The median time to progression was 4.5 months (range 1-18 months), the median response duration was 7 months (range 2-18 months) and the median survival duration was 10 months (range 2-26+). The oral vincap should be considered as an alternative to single agent capecitabine or vinorelbine in ABC refractory to antra-taxane combination.

  8. Minero-chemical composition as environmental quality assessment tool of an artificial water reservoir: the case of the "Pietra del Pertusillo" lake (Basilicata, Italia)

    NASA Astrophysics Data System (ADS)

    fortunato, elisabetta; mongelli, giovanni; paternoster, michele; sinisi, rosa

    2016-04-01

    The Pietra del Pertusillo fresh-water reservoir is an artificial lake located in the High Agri River Valley (Basilicata); its dam was completed in 1963 for producing hydroelectric energy and providing water for human use to Puglia and Basilicata southern Italian regions (approximately 2 million people). Pertusillo lake lies within a national park because of the presence of many special protected areas. This reservoir is a natural laboratory for assessing the sediment pollution from human activities, including: waste-water treatment plants, landfills, farms, treatment oil plant, plastics and other industrial activities. In addition, the Pertusillo reservoir is located in the area of the largest oil field of continental Europe. This anthropogenic pressure may thus represent an impact factor on the environmental equilibrium and consequently the knowledge and control on their quality represents a relevant environmental challenge. This study reports the preliminary results of a multidisciplinary (sedimentological, mineralogical, geochemical) PhD research focused on the analysis of the lacustrine sediments filling the Pietra del Pertusillo fresh-water reservoir. The lakes and its sediments represent the natural sink for nutrients and possible pollutants which tend to accumulate in relation to the nature and composition of the solid matrix but also the concentration and characteristics of the substances themselves. Moreover the deeper sediments, deposited under undisturbed condition, represent the "historical memory" of the ecosystem. Sub-aqueous lake sediments were investigated in May 2014, sampled using a small platform and a gravity corer (UWITEC, Austria) of 90 mm diameter which allowed to drill 19 cores up to 2 m long from the sediment/water interface. Successively cores were studied and described by using facies analysis techniques; a large number of core samples (147) were collected from the working half of each core, stored in HPDE containers, and frozen at -20°C for subsequent chemical and mineralogical analysis. Further, in order to assess the provenance effects on the composition of lake sediments, the bedrock (Meso-Cenozoic rocks and Quaternary fluvial-lacustrine deposits) and the stream sediments of the main "Pietra del Pertusillo" tributaries, close to the detrital supply entry points of Pietra del Pertusillo lake were also sampled. The mineralogical composition was obtained from randomly oriented powders by XRPD. Chemistry (major, minor, and trace elements) was performed on powdered samples by ICP-MS technique after a four acids digestion and lithium metaborate/tetraborate fusion to facilitate the destruction of possible resistate minerals. Preliminary data related to the stream sediments show that both major and minor elements (including heavy metals, barium and arsenic) have a minor variability and are close to the median values of the bedrock. The mineralogical composition of the analysed samples can explain the elemental relationships,thus excluding any anthropogenic input. The mineralogical composition of the lacustrine samples is made of quartz, carbonates, feldspars, muscovite/illite, chlorite, and interstratified clay minerals, and it is constant throughout the cores. Finally, as further step ot he research plan, we are processing 20 of all lake samples with the highest peaks of interstratified clay minerals, which likely represent the most reactive phases in our sediment-water system.

  9. 5. View north, south and east facade of Lake Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. View north, south and east facade of Lake Forest (original Forest Cottage structure incorporated into renamed structure) - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  10. 51. Third Floor, Lake Forest, west center room, looking west, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Third Floor, Lake Forest, west center room, looking west, part of original Forest Cottage as of 1901. - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  11. 7. View southwest, east facade of Lake Forest (original Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. View southwest, east facade of Lake Forest (original Forest Cottage structure incorporated into renamed structure) - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  12. 8. View west, southeast facade of Forest Lobby/Offices and Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. View west, southeast facade of Forest Lobby/Offices and Forest Towers, south facade Forest Hall. - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  13. 4. View southeast, west facade of Lake Forest (original Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. View southeast, west facade of Lake Forest (original Forest Cottage structure incorporated into renamed structure) - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  14. 6. View north, southeast facade of Forest Lobby/Offices and Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View north, southeast facade of Forest Lobby/Offices and Forest Towers. - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  15. 19. View west, foreground, north facade of Forest East Suites, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. View west, foreground, north facade of Forest East Suites, background north & east facades of Forest Hall. - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  16. 27. View east, foreground north facade of Forest Hall, background ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. View east, foreground north facade of Forest Hall, background north facade of Forest East Suites. - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  17. 3. View northeast, west facade of Lake Forest (original Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. View northeast, west facade of Lake Forest (original Forest Cottage structure incorporated into renamed structure) - Lake Placid Club, Forest Wing, East side of Mirror Lake Drive, North of State Route 86 & Main, North Elba, Essex County, NY

  18. 75 FR 34214 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ..., Nueva Italia, Estado de Michoac n, Mexico; Esquina de Ignacio Allende Numero Y Lazaro Cardenas Norte Numero 500, Nueva Italia, Estado de Michoac n, Mexico; (ENTITY) Dated: June 9, 2010. Adam J. Szubin...

  19. Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family.

    PubMed

    Dai, Qi; Ren, Aiming; Westholm, Jakub O; Duan, Hong; Patel, Dinshaw J; Lai, Eric C

    2015-01-01

    Recently, the BEN (BANP, E5R, and NAC1) domain was recognized as a new class of conserved DNA-binding domain. The fly genome encodes three proteins that bear only a single BEN domain ("BEN-solo" factors); namely, Insensitive (Insv), Bsg25A (Elba1), and CG9883 (Elba2). Insv homodimers preferentially bind CCAATTGG palindromes throughout the genome to mediate transcriptional repression, whereas Bsg25A and Elba2 heterotrimerize with their obligate adaptor, Elba3 (i.e., the ELBA complex), to recognize a CCAATAAG motif in the Fab-7 insulator. While these data suggest distinct DNA-binding properties of BEN-solo proteins, we performed reporter assays that indicate that both Bsg25A and Elba2 can individually recognize Insv consensus sites efficiently. We confirmed this by solving the structure of Bsg25A complexed to the Insv site, which showed that key aspects of the BEN:DNA recognition strategy are similar between these proteins. We next show that both Insv and ELBA proteins are competent to mediate transcriptional repression via Insv consensus sequences but that the ELBA complex appears to be selective for the ELBA site. Reciprocally, genome-wide analysis reveals that Insv exhibits significant cobinding to class I insulator elements, indicating that it may also contribute to insulator function. Indeed, we observed abundant Insv binding within the Hox complexes with substantial overlaps with class I insulators, many of which bear Insv consensus sites. Moreover, Insv coimmunoprecipitates with the class I insulator factor CP190. Finally, we observed that Insv harbors exclusive activity among fly BEN-solo factors with respect to regulation of Notch-mediated cell fate choices in the peripheral nervous system. This in vivo activity is recapitulated by BEND6, a mammalian BEN-solo factor that conserves the Notch corepressor function of Insv but not its capacity to bind Insv consensus sites. Altogether, our data define an array of common and distinct biochemical and functional

  20. Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family

    PubMed Central

    Dai, Qi; Ren, Aiming; Westholm, Jakub O.; Duan, Hong; Patel, Dinshaw J.

    2015-01-01

    Recently, the BEN (BANP, E5R, and NAC1) domain was recognized as a new class of conserved DNA-binding domain. The fly genome encodes three proteins that bear only a single BEN domain (“BEN-solo” factors); namely, Insensitive (Insv), Bsg25A (Elba1), and CG9883 (Elba2). Insv homodimers preferentially bind CCAATTGG palindromes throughout the genome to mediate transcriptional repression, whereas Bsg25A and Elba2 heterotrimerize with their obligate adaptor, Elba3 (i.e., the ELBA complex), to recognize a CCAATAAG motif in the Fab-7 insulator. While these data suggest distinct DNA-binding properties of BEN-solo proteins, we performed reporter assays that indicate that both Bsg25A and Elba2 can individually recognize Insv consensus sites efficiently. We confirmed this by solving the structure of Bsg25A complexed to the Insv site, which showed that key aspects of the BEN:DNA recognition strategy are similar between these proteins. We next show that both Insv and ELBA proteins are competent to mediate transcriptional repression via Insv consensus sequences but that the ELBA complex appears to be selective for the ELBA site. Reciprocally, genome-wide analysis reveals that Insv exhibits significant cobinding to class I insulator elements, indicating that it may also contribute to insulator function. Indeed, we observed abundant Insv binding within the Hox complexes with substantial overlaps with class I insulators, many of which bear Insv consensus sites. Moreover, Insv coimmunoprecipitates with the class I insulator factor CP190. Finally, we observed that Insv harbors exclusive activity among fly BEN-solo factors with respect to regulation of Notch-mediated cell fate choices in the peripheral nervous system. This in vivo activity is recapitulated by BEND6, a mammalian BEN-solo factor that conserves the Notch corepressor function of Insv but not its capacity to bind Insv consensus sites. Altogether, our data define an array of common and distinct biochemical and functional

  1. First-line cisplatin with docetaxel or vinorelbine in patients with advanced non-small-cell lung cancer: a quality of life directed phase II randomized trial of Gruppo Oncologico Italia Meridionale.

    PubMed

    Gebbia, Vittorio; Lorusso, Vito; Galetta, Domenico; Caruso M, Michele; Palomba, Giuseppe; Riccardi, Fernando; Borsellino, Nicolò; Carrozza, Francesco; Leo, Silvana; Ferraù, Francesco; Cinieri, Saverio; Mancuso, Gianfranco; Mancarella, Sergio; Colucci, Giuseppe

    2010-08-01

    Quality of life (QoL) has gained greater importance in the management of metastatic non-small-cell lung cancer due to the palliative nature of treatment. Docetaxel (DCT) and cisplatin (CDDP) doublet has been reported to be associated to a better QoL than the weekly vinorelbine (VNR) and CDDP regimen. Recently a newer more tolerated schedule of the VNR/CDDP regimen has been published and is widely employed in medical practice. The impact of these regimens on patients' QoL as well as symptoms control and type and grading chemo-related side-effects has been compared prospectically. Patients received CDDP 75 mg/m(2) plus DCT 75 mg/m(2) on day 1 every weeks (arm A) or CDDP 80 mg/m(2) on day 1 plus VNR 30 mg/m(2) day 1 and 8 every 3 weeks (arm B). G-CSF and/or EPO were employed as needed. Health-related QoL was assessed at entry and after every cycle by the EORTC-QLQ-C30 and LC13 questionnaires, toxicity by the NCI-NCCN CTC vs 2, and intent-to-treat objective response by the Recist criteria. The QoL questionnaires were completed by 37 pts (88%) in the DCT/CDDP arm and 39 pts (87%) in the VNR/CDDP one. Baseline mean scores and rates at which pts failed to complete QoL assessment were similar in the two arms. Global health status of the EORTC QLQ-C30 scale and specific symptoms control (LC13 module) improved during treatment without any statistically significant difference between the two arms. Emotional functioning remained stable in both groups during treatment, whereas physical and role improved slightly. In the DCT/CDDP arm 14 pts (33%; 95%CL 24-40%) had PR, and 10 (24%) SD for a 57% TGCR. In the VNR/CDDP arm 12 pts (27%) achieved PR, 18 (41%) SD a 68% TGCR. Differences were not statistically significant. Median time-to-progression was 4.2 months in the DCT/CDDP arm and 4.5 months in the VNR/CDDP one, and median overall survival was 12.1 (range 1-26+ months) and 12.5 months (range 1-28+ months) for DCT/CDDP and VNR/CDDP arms, respectively. Febrile neutropenia rate was higher in the VNR/CDDP arm (p=0.02) as well as G3-4 anemia (p=0.005) and G-CSF/EPO use (p=0.019). Global and specific health-related QoL data similar in both treatment groups with no statistically significant difference. Efficacy measures, overall response rate, time-to-progression and overall survival were equivalent in both arms. However, severe anemia and febrile neutropenia are statistically more frequent in the VNR/CDDP arm than in the DCT/CDDP one. These data should be considered in treatment decision-making for pts with advanced non-small-cell lung cancer and for the design of future trials with chemotherapy plus biologics. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

  2. Adjuvant chemotherapy with epirubicin, leucovorin, 5-fluorouracil and etoposide regimen in resected gastric cancer patients: a randomized phase III trial by the Gruppo Oncologico Italia Meridionale (GOIM 9602 Study).

    PubMed

    De Vita, F; Giuliani, F; Orditura, M; Maiello, E; Galizia, G; Di Martino, N; Montemurro, F; Cartenì, G; Manzione, L; Romito, S; Gebbia, V; Ciardiello, F; Catalano, G; Colucci, G

    2007-08-01

    This randomized, multicenter, phase III trial evaluated the efficacy and safety of the combination of epirubicin, leucovorin, 5-fluorouracil and etoposide (ELFE regimen) as adjuvant therapy for radically resected gastric cancer patients. From June 1996 to June 2001, 228 stage IB-IIIB gastric cancer patients were enrolled. All patients received a total or subtotal gastrectomy with at least a D1 lymphoadenectomy and were randomly assigned to receive surgery alone or surgery followed by chemotherapy. A total number of 630 cycles was delivered with a median number of 5. With a median follow-up of 60 months, the 5-year overall survival (OS) was 48% in the treatment arm and 43.5% in the control arm [hazard ratio (HR) 0.91; 95% confidence interval (CI) 0.69-1.21; P = 0.610); the 5-year disease-free survival (DFS) was 44% in the treatment arm and 39% in the control arm (HR 0.88; 95% CI 0.78-0.91; P = 0.305). In node-positive patients, the 5-year OS was 41% in the treatment arm and 34% in the control arm (HR 0.84; 95% CI 0.69-1.01; P = 0.068), while the 5-year DFS was 39% in the treatment arm and 31% in the control arm (HR 0.88; 95% CI 0.78-0.91; P = 0.051). The most common grade 3-4 toxic effects according to World Health Organization criteria were hematological and gastrointestinal. In radically resected gastric cancer patients, adjuvant chemotherapy with ELFE regimen does not improve OS over surgery alone.

  3. Cisplatin plus weekly vinorelbine versus cisplatin plus vinorelbine on days 1 and 8 in advanced non-small cell lung cancer: a prospective randomized phase III trial of the G.O.I.M. (Gruppo Oncologico Italia Meridionale).

    PubMed

    Gebbia, Vittorio; Galetta, Domenico; Lorusso, Vito; Caruso, Michele; Verderame, Francesco; Pezzella, Giuseppe; Borsellino, Nicolò; Durini, Ernesto; Valenza, Roberto; Agostara, Biagio; Colucci, Giuseppe

    2008-09-01

    A phase III randomized trial was carried out to compare two schedules of the vinorelbine (VNR)-cisplatin (CDDP) regimen in patients with locally advanced unresectable poor prognosis stage IIIB or metastatic stage IV non-small cell lung cancer. The primary endpoints were overall survival (OS) and analysis of toxicity, while secondary endpoints included response rates, time-to-progression (TTP) and quality of life (QoL). Eligible patients were randomized to receive: (a) VNR 25mg/m(2) on day 1, 8 and 15 plus CDDP 100mg/m(2) on day 1 every 4 weeks or (b) VNR 30 mg/m(2) on day 1 and 8 plus CDDP 80 mg/m(2) on day 1 every 3 weeks. All patients were chemotherapy-naïve and had an ECOG performance status (PS) of 0-1. Overall 278 patients were enrolled into the trial. Overall response rate was 34% (95% CL 26-42%) in the weekly VNR/CDDP arm, and 32% (95% CL 24-40%) in patients treated with day 1-8 VNR/CDDP without any statistically significant difference. Median TTP was 4.5 and 4.6 months respectively for weekly VNR/CDDP arm and the day 1-8 VNR/CDDP one. This difference was not statistically significant (log-rank test, p=0.818). Median OS was 9.45 and 10 months respectively for weekly VNR/CDDP arm and the day 1-8 VNR/CDDP one without statistically a significant difference (log-rank test, p=0.259). The 1- and 2-year survival rates were 31 and 36%, and 10 and 11% respectively. The incidence of severe neutropenia (34% versus 68%; p=0.0001) and of febrile neutropenia (5% versus 12%; p=0.026), as well as the rate of therapy omissions (10% versus 24%; p=0.0037) were higher in the weekly VNR/CDDP arm than in the day 1-8 VNR/CDDP one. The weekly VNR/CDDP regimen was associated with a lower received dose intensity in a statistically significant fashion (9% versus 22%; p=0.0001) and with a lower non-statistically significant quality of life score as compared to the day 1-8 VNR/CDDP schedule. The combination of day 1-8 VNR plus CDDP every 3 weeks is less toxic and better tolerated than the regimen of weekly VNR plus CDDP every 4 weeks. The two schedules are equivalent in terms of overall response rate, median time-to-progression and overall survival. The combination of VNR on day 1-8 plus CDDP every 3 weeks may be considered as a reference regimen for the treatment of patients with advanced disease and those who deserve a postoperative therapy, and for future studies.

  4. Vinorelbine and 5-fluorouracil bolus and/or continuous venous infusion plus levofolinic acid as second-line chemotherapy for metastatic breast cancer: an analysis of results in clinical practice of the Gruppo Oncologico Italia Meridionale (GOIM).

    PubMed

    Gebbia, Vittorio; Caruso, Michele; Borsellino, Nicolo; Ajello, Rosanna; Tirrito, Maria Lina; Chiarenza, Maurizio; Valenza, Roberto; Verderame, Francesco; Varvara, Francesca; Marrazzo, Antonio; Bajardi, Eugenia; Ferrao, Francesco; Bordonaro, Roberto; Tralongo, Paolo

    2006-01-01

    This retrospective study evaluated the activity and toxicity profile of a regimen of vinorelbine and 5-fluorouracil with levofolinic acid, given to a large series of patients with recurrent or refractory metastatic breast cancer after first-line chemotherapy. Overall, 286 evaluable patients were included in the analysis. Two chemotherapy schedules were reviewed: a) the bolus regimen consisted of levofolinic acid 100 mg/m2 and 5-fluorouracil 375 mg/m2, both administered i.v. on days 1,2 and 3, plus vinorelbine 25 mg/m2 i.v. bolus on days 1 and 8 every 3 weeks; b) the infusional regimen of levofolinic acid 100 mg/m2 given as a 2-hour infusion, followed by 5-fluorouracil 400 mg/m2 i.v. bolus and by 5-fluorouracil 600 mg/m2 administered as 22-hour continuous venous infusion (c.v.i) for 2 days, plus vinorelbine i.v. bolus on days 1 and 8. Overall, twelve patients achieved a complete response (4%; 95%CL 2%-7%) and 115 patients showed a partial response (40%, 95%CL 34%-46%), for an overall response rate of 44% (95CL 39%-50%). Sixty-one patients had stable disease (21%) and 98 patients progressive disease (34%). The tumor growth control rate was 63% (95%CL 60%-71%). Patients with soft tissue metastases as the dominant disease showed the highest response rate (56%), followed by viscera (48%) and bone (33%). The difference in response rate between patients with dominant visceral disease versus those with dominant bone disease was statistically significant (p=0.038). Patients treated with the bolus schedule achieved a 40% overall response rate with a 5% complete response rate, while those who received the infusional regimen had a 48% overall response rate with a 5% complete response rate. This difference was not statistically significant (p=0.164). The overall median duration of objective responses was 8.3 months (range 4-14 months), median time to progression of the all series was 6.1 months (range 2-24 months) and the median overall survival was 14.6 months (range 3-32). There was a statistically significant difference in survival among responder and non-responder patients (p=0.0009). The results of this large off-trial analysis confirmed the clinical activity and adverse-event profile reported in controlled clinical trials of the vinorelbine/ 5-fluorouracil with levofolinic acid regimen in clinical practice. This combination regimen was active with a low toxicity burden and, therefore, represents a good therapeutic choice for patients who require second-line chemotherapy.

  5. A multicenter phase II randomized trial of docetaxel/gemcitabine versus docetaxel/capecitabine as first-line treatment for advanced breast cancer: a Gruppo Oncologico Italia Meridionale study.

    PubMed

    Vici, P; Giotta, F; Di Lauro, L; Sergi, D; Vizza, E; Mariani, L; Latorre, A; Pizzuti, L; D'Amico, C; Giannarelli, D; Colucci, G

    2011-01-01

    To evaluate two docetaxel-based regimens as first-line treatment in advanced breast cancer patients. Patients were randomly assigned to docetaxel/gemcitabine (arm A: docetaxel 75 mg/m(2) on day 1, gemcitabine 1,000 mg/m(2) on days 1 and 8) or docetaxel/capecitabine (arm B: docetaxel 75 mg/m(2) on day 1, capecitabine 1,250 mg/m(2) twice daily on days 1-14); both chemotherapy regimens were repeated every 21 days. The primary objective of the study was to evaluate the response rate. Seventy-two patients were enrolled (36 each in arms A and B). Responses according to intention-to-treat analysis were as follows: arm A, 41.7% [95% confidence interval (CI) 25.6-57.8]; arm B, 38.9% (95% CI 23-54.8). Median progression-free survival was 10.9 months (95% CI 8.1-13.7) in arm A and 10 months (95% CI 8.8-11.2) in arm B. Overall survival was 26 months (95% CI 22.0-30.0) in arm A and 28 months (95% CI 23.4-32.6) in arm B. Both treatments were well tolerated; myelosuppression was the dose-limiting toxicity, with grade 3-4 neutropenia in 13.8 and 19.4% of the patients in arms A and B, respectively. No relevant differences in other toxicities were observed in the two arms, except for diarrhea (13.9%) and hand-foot syndrome (11.1%), which occurred only in arm B. Both regimens were active and well tolerated in advanced breast cancer. Copyright © 2011 S. Karger AG, Basel.

  6. Cisplatin, fotemustine and whole-brain radiotherapy in non-small cell lung cancer patients with asymptomatic brain metastases: a multicenter phase II study of the Gruppo Oncologico Italia Meridionale (GOIM 2603).

    PubMed

    Galetta, D; Gebbia, V; Silvestris, N; Ferraù, F; Carrozza, F; Cigolari, S; Russo, P; Calista, F; Adamo, V; Colucci, G

    2011-04-01

    More than 50% of brain metastases (BMs) occur in advanced non-small cell lung cancer (NSCLC) patients. Untreated patients with BMs have a poor prognosis with a median survival of 2 months. In most cases BMs are multiple and their optimal therapy is whole-brain radiation therapy (WBRT). The role of systemic therapies for these patients is still a matter for investigation due to concerns about the ability of these drugs to cross the blood-brain barrier (BBB). Cisplatin (CDDP) remains the backbone for medical treatment of NSCLC and fotemustine (FTM) is a nitrosurea able to cross the BBB. Patients with advanced NSCLC, ECOG performance status (PS) 0-1 and multiple BMs not amenable to surgery or stereotactic radiotherapy were treated with 2 cycles of FTM 80 mg/m(2) days 1, 8 and CDDP 80 mg/m(2) day 1, every 3 weeks followed by WBRT 30 Gy (3 Gy daily in 10 fractions). Radiological restaging was performed before WBRT to assess the role of chemotherapy both for cranial and extracranial disease. Patients with disease control (DC: complete response plus partial response) received 4 more cycles. To assess the basic activities of daily living (ADL), the Barthel ADL Index was used to score patients' performance every 2 cycles. The trial design provides a two-step evaluation according to the optimal two-stage design of Simon. In the first phase 29 patients were enrolled in order to verify if this schedule showed more than 25% response rate both for cranial and extracranial disease. If so, enrollment added up to a total of 81 patients. After the first evaluation 4 out of 29 patients were excluded from the study (3 untreated/1 not included for administrative reasons). At the time of the planned interim analysis patient's characteristics were the following: median age 61 years (range 44-70), M/F = 16/9, adenocarcinoma 11, squamous 5, large cell 2, undefined NSCLC 7; PS 0/1 in 11/14 cases, median Barthel Index score was 20 [13-20]. Three (12%) partial responses were observed, 9 subjects (36%) with stable disease and 13 (52%) showing disease progression. These data did not satisfy the pre-planned hypothesis and the study was stopped. At the time of the first evaluation before WBRT 12/25 (48%) patients had a systemic DC in contrast with 15/25 (60%) patients with BMs DC. Chemotherapy was relatively well tolerated with a prevalence of asthenia as the most relevant specific toxicity while the haematological toxicity was mild. CDDP and FTM combined with WBRT do not represent a therapeutic option for patients with NSCLC. Therefore further studies to evaluate the combination of systemic treatments with WBRT are warranted. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  7. Irinotecan (CPT-11) and mitomycin-C (MMC) as second-line therapy in advanced gastric cancer: a phase II study of the Gruppo Oncologico dell' Italia Meridionale (prot. 2106).

    PubMed

    Giuliani, Francesco; Molica, Stefano; Maiello, Evaristo; Battaglia, C; Gebbia, Vittorio; Di Bisceglie, Maurizio; Vinciarelli, Gianluca; Gebbia, Nicola; Colucci, Giuseppe

    2005-12-01

    The aim of this study was to evaluate the activity and toxicity of a combination regimen of CPT-11 and mitomycin-c as second-line chemotherapy for pretreated patients with advanced, metastatic, or both, gastric adenocarcinoma. Patients with pretreated metastatic disease or early relapsed after adjuvant chemotherapy were enrolled. Entry criteria included histologic/cytologic diagnosis of gastric adenocarcinoma, age 18 to 75 years, performance status > or =70 (Karnofsky scale), bi-dimensionally measurable disease. Patients received CPT-11 and mitomycin-c at the dosage of 150 mg/m2 on days 1 and 15, and 8 mg/m2 on day 1, respectively, every 4 weeks. The disease evaluation was done every 3 cycles. Among the 38 patients we observed, 1 (3%) complete response and 11 (29%) partial responses for an overall response rate of 32% according to an intent-to-treat analysis. The median duration of response was 6.5 months. The median time to progression was 4 months with a median overall survival 8 months. All patients were evaluable for toxicity and the only grade 3-4 observed toxicities were leukopenia (8%), neutropenia (21%), and anemia (5%). The combination of CPT-11 and mitomycin-c is an active and well tolerated second-line treatment in pretreated gastric cancer patients. Further studies are needed to test its role in first-line treatment.

  8. In para totale...una cosa da panico...sulla lingua dei giovani in Italia (In para totale...una cosa da panico...The Language of Young People in Italy).

    ERIC Educational Resources Information Center

    Marcato, Carla

    1997-01-01

    Describes and analyzes the language of young people in Italy today. Particular focus is on the expressions using "para" (e.g., "in para totale" = to be very bored or worried) and the phrase "una cosa da panico" (something terrible or its opposite something wonderful). (CFM)

  9. Second-line chemotherapy in advanced pancreatic carcinoma: a multicenter survey of the Gruppo Oncologico Italia Meridionale on the activity and safety of the FOLFOX4 regimen in clinical practice.

    PubMed

    Gebbia, V; Maiello, E; Giuliani, F; Borsellino, N; Caruso, M; Di Maggio, G; Ferraù, F; Bordonaro, R; Verderame, F; Tralongo, P; Di Cristina, L; Agueli, R; Russo, P; Colucci, G

    2007-06-01

    In daily clinical practice second-line chemotherapy (SLCT) is frequently given to patients with advanced pancreatic cancer failing gemcitabine-based first-line chemotherapy without solid scientific support. A retrospective survey was carried out including 42 patients. Patients received standard FOLFOX4 regimen biweekly until progression or unacceptable toxicity. Six partial responses (14%) and 16 stabilizations (38%) were recorded for a tumor growth control rate of 57%. The median time to progression (TtP) was 4 months (range 1-7 months), and median overall survival (OS) was 6.7 months (range 2-9 months). A stabilization of performance status (PS) and a subjective improvement of cancer-related symptoms were recorded in 27 patients. Data presented in this paper support the use of FOLFOX4 regimen in the second-line treatment of adenocarcinoma of the pancreas patients. The use of SLCT, however, should be carefully proposed to patients with good PS or those who had a good response to first-line therapy.

  10. Cisplatin/Pemetrexed Followed by Maintenance Pemetrexed Versus Carboplatin/Paclitaxel/Bevacizumab Followed by Maintenance Bevacizumab in Advanced Nonsquamous Lung Cancer: The GOIM (Gruppo Oncologico Italia Meridionale) ERACLE Phase III Randomized Trial.

    PubMed

    Galetta, Domenico; Cinieri, Saverio; Pisconti, Salvatore; Gebbia, Vittorio; Morabito, Alessandro; Borsellino, Nicola; Maiello, Evaristo; Febbraro, Antonio; Catino, Annamaria; Rizzo, Pietro; Montrone, Michele; Misino, Andrea; Logroscino, Antonio; Rizzi, Daniele; Di Maio, Massimo; Colucci, Giuseppe

    2015-07-01

    Cisplatin with pemetrexed (CP) and carboplatin with paclitaxel and bevacizumab (CbTB) are standard first-line treatments for patients with advanced nonsquamous (NS) non-small-cell lung cancer (NSCLC). Quality of life (QoL) is a key objective in the management of advanced NSCLC. Thus, effect on QoL could be an additional factor in the choice of treatment. Patients with untreated stage IIIB/IV NS-NSCLC and Eastern Cooperative Oncology Group performance status of 0 or 1 were randomized to receive first-line chemotherapy with cisplatin 75 mg/m(2) and pemetrexed 500 mg/m(2), every 3 weeks, for 6 cycles followed by maintenance pemetrexed; or carboplatin area under the curve 6, paclitaxel 200 mg/m(2), and bevacizumab 15 mg/kg, every 3 weeks, for 6 cycles followed by maintenance bevacizumab. The primary end point was the difference in QoL between the 2 treatment arms after 12 weeks of maintenance, measured using the EuroQoL 5 Dimensions-Index (EQ5D-I) and EQ5D-visual analogue scale (EQ5D-VAS). One hundred eighteen patients were randomized to CP (n = 60) or CbTB (n = 58). Baseline characteristics were well balanced. The proportion of patients evaluable for the primary end point was lower than planned. After 12 weeks of maintenance, the difference between mean changes in EQ5D-I was 0.137, favoring CP (95% confidence interval [CI], -0.02 to 0.29, Wilcoxon P = .078), although not statistically significant; and the difference between mean changes in EQ5D-VAS was 0.97 (95% CI, -9.37 to 11.31, Wilcoxon P = .41). Although the study was underpowered because of a small number of patients evaluable for the primary end point, QoL did not differ between treatment arms. Other factors such as comorbidities and schedule should be used when deciding on first-line treatment. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Peak luminosities of bursts from GRO J1744-28 measured with the RXTE PCA Italia: wij post 17 two 4s - a one man marching band - got darn bright

    NASA Astrophysics Data System (ADS)

    Jahoda, Keith; Stark, Michael J.; Strohmayer, Tod E.; Zhang, William; Morgan, Edward H.; Fox, Derek

    1999-01-01

    GRO J1744-28, discovered by BATSE in December 95, is the second neutron star system known to produce frequent accretion powered bursts. The system has been regularly monitored with the RXTE PCA since the peak of the first outburst in January 96 at which time the observed persistent and bursting count rates were ~25000ct/sec and ~150000ct/sec, with corresponding instrumental deadtimes of ~10% and >=50%. We present a model which allows the reconstruction of the true incident count rate in the presence of enormous deadtime and use the model to derive a history of the peak luminosities and fluences of the bursts as a function of time. During the peak of the January 1996 and January 1997 outbursts, when the persistent emission was >=1 Crab, we infer peak luminosities of ~100 times the Eddington luminosity, and a ratio of persistent emission to integrated burst emission of ~34.

  12. In para totale...una cosa da panico...sulla lingua dei giovani in Italia (In para totale...una cosa da panico...The Language of Young People in Italy).

    ERIC Educational Resources Information Center

    Marcato, Carla

    1997-01-01

    Describes and analyzes the language of young people in Italy today. Particular focus is on the expressions using "para" (e.g., "in para totale" = to be very bored or worried) and the phrase "una cosa da panico" (something terrible or its opposite something wonderful). (CFM)

  13. Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: a prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale.

    PubMed

    Colucci, Giuseppe; Giuliani, Francesco; Gebbia, Vittorio; Biglietto, Maria; Rabitti, Piergiorgio; Uomo, Generoso; Cigolari, Silvio; Testa, Antonio; Maiello, Evaristo; Lopez, Massimo

    2002-02-15

    A prospective, randomized Phase III trial was performed to determine whether, compared with gemcitabine (GEM) alone, the addition of cisplatin (CDDP) to GEM was able to improve the time to disease progression and the clinical benefit rate in patients with advanced pancreatic adenocarcinoma. The objective response rate, overall survival rate, and toxicity patterns of patients in the two treatment arms were evaluated as secondary end points. Patients with measurable, locally advanced and/or metastatic pancreatic adenocarcinoma were randomized to receive GEM (Arm A) or a combination of GEM and CDDP (Arm B). In Arm A, a dose of 1000 mg/m(2) GEM per week was administered for 7 consecutive weeks, and, after a 2-week rest, treatment was resumed on Days 1, 8, and 15 of a 28-day cycle for 2 cycles. In Arm B, CDDP was given at a dose of 25 mg/m(2) per week 1 hour before GEM at the same dose that was used in Arm A. On Day 22, only GEM was administered. Patients were restaged after the first 7 weeks of therapy and then again after the other 2 cycles. A total of 107 patients entered the trial: Fifty-four patients were randomized to Arm A, and 53 patients were randomized to Arm B. The median time to disease progression was 8 weeks in Arm A and 20 weeks in Arm B; this difference was statistically significant (P = 0.048). In Arm A, one complete response and four partial responses were recorded on the basis of an intent-to-treat analysis, with an overall response rate of 9.2% (95% confidence interval [95%CI], 3-20%). In Arm B, there were no complete responses, whereas 14 partial responses were achieved, with an overall response rate of 26.4% (95%CI, 15-40%). This difference in the overall response rates was statistically significant (P = 0.02). The tumor growth control rate (i.e., total number of patients who achieved complete responses, partial responses, and stable disease) was 42.6% (95%CI, 29-57%) in Arm A and 56.6% (95%CI, 42-70%) in Arm B. A clinical benefit was observed in 21 of 43 patients (49%) in Arm A and in 20 of 38 patients (52.6%) in Arm B without any significant difference. The median overall survival was 20 weeks for patients in Arm A and 30 weeks for patients in Arm B (P = 0.43). Toxicity was mild in both treatment arms, with no significant differences between the two groups except for the statistically higher incidence of Grade 1-2 asthenia in Arm B (P = 0.046). The addition of CDDP to GEM significantly improved the median time to disease progression and the overall response rate compared with GEM alone. The clinical benefit rate was similar in both arms, whereas the median overall survival rate was more favorable for Arm B, although the difference did not attain statistical significance. The authors conclude that the combination of CDDP and GEM currently may be considered as an optimal treatment for patients with locally advanced and/or metastatic adenocarcinoma of the pancreas. Copyright 2002 American Cancer Society. DOI 10.1002/cncr.10323

  14. A resolution commemorating the lives and work of Jesuit Fathers Ignacio Ellacuria, Ignacio Martin-Baro, Segundo Montes, Amando Lopez, Juan Ramon Moreno, Joaquin Lopez y Lopez, and housekeeper Julia Elba Ramos and her daughter Celina Mariset Ramos on the occasion of the 20th anniversary of their deaths on November 16, 1989, at the Universidad Centroamericana Jose Simeon Canas located in San Salvador, El Salvador.

    THOMAS, 111th Congress

    Sen. Feingold, Russell D. [D-WI

    2009-10-26

    10/26/2009 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S10741-10742; text as passed Senate: CR S10741-10742; text of measure as introduced: CR S10737-10738) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  15. A resolution commemorating the lives and work of Jesuit Fathers Ignacio Ellacuria, Ignacio Martin-Baro, Segundo Montes, Amando Lopez, Juan Ramon Moreno, Joaquin Lopez y Lopez, and housekeeper Julia Elba Ramos and her daughter Celina Mariset Ramos on the occasion of the 20th anniversary of their deaths on November 16, 1989, at the Universidad Centroamericana Jose Simeon Canas located in San Salvador, El Salvador.

    THOMAS, 111th Congress

    Sen. Feingold, Russell D. [D-WI

    2009-10-26

    10/26/2009 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  16. A resolution commemorating the lives and work of Jesuit Fathers Ignacio Ellacuria, Ignacio Martin-Baro, Segundo Montes, Amando Lopez, Juan Ramon Moreno, Joaquin Lopez y Lopez, and housekeeper Julia Elba Ramos and her daughter Celina Mariset Ramos on the occasion of the 20th anniversary of their deaths on November 16, 1989, at the Universidad Centroamericana Jose Simeon Canas located in San Salvador, El Salvador.

    THOMAS, 111th Congress

    Sen. Feingold, Russell D. [D-WI

    2009-10-26

    Senate - 10/26/2009 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  17. Time Transfer With the Galileo Precise Timing Facility

    DTIC Science & Technology

    2007-11-01

    Alenia Space- Italia c. Marche 41, 10146 Torino, Italy, Tel: +390117180545 E-mail: renzo.zanello@thalesaleniaspace.com Alberto Busso Thales...Alenia Space- Italia c. Marche 41, 10146 Torino, Italy, Tel: +390117180008 E-mail: alberto.busso@thalesaleniaspace.com Edoardo Detoma Sistemi...AND ADDRESS(ES) Thales Alenia Space- Italia ,c. Marche 41,10146 Torino, Italy,CA,91109 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING

  18. Performance Evaluation Test of the Orbit Screen Model 68A and the Komplet Model 48-25 Rock Crusher

    DTIC Science & Technology

    2008-08-01

    screen and on a Komplet Italia , s.r.l., Model 48-25 rock crusher. The test was conducted during August 2008 at a U.S. Army test site in central... Italia , s.r.l., Model 48-25 Rock Crusher.......................................................... 2 2.3 ASV SR-80 Rubber-Tracked Skid-Steer Loader... Italia , s.r.l., Rock Crusher Testing ......................................................................... 16 5.1 Crushing Performance Test

  19. Ho-doped Soft Glass Optical Fibers for Coherent Wavelength Sources Above 2 Micron

    DTIC Science & Technology

    2010-12-01

    Politecnico di Torino – Dipartimento di Scienza dei Materiali e Ingegneria Chimica Corso Duca degli Abruzzi, 24 – 10129 Torino Italia tel: +39...Abruzzi, 24 – 10129 Torino Italia tel: +39 011 564 4707 fax: +39 011 564 4699 e-mail: daniel.milanese@polito.it url: www.composites.polito.it...Materiali e Ingegneria Chimica Corso Duca degli Abruzzi, 24 – 10129 Torino Italia tel: +39 011 564 4707 fax: +39 011 564 4699 e-mail

  20. Systematic Instruction in Reading for Spanish-Speaking Students.

    ERIC Educational Resources Information Center

    Duran, Elva; Shefelbine, John; Carnine, Linda; Maldonado-Colon, Elba; Gunn, Barbara

    This book addresses the area of reading and literacy instruction for Spanish-speaking students. Ten chapters focus on the following: (1) "Direct Instruction" (Elva Duran and Douglas Carnine); (2) "Developing the Foundations of Literacy: Oracy" (Elba Maldonado-Colon); (3) "Language Development and Instruction" (Linda…

  1. 75 FR 44155 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ...) Modified Coffee County, Alabama, and Incorporated Areas Docket No.: FEMA-B-1053 Beaverdam Creek... of Elba, downstream of the intersection Unincorporated Areas of of County Road 404 and Reese Coffee... Coffee County. Approximately 14,458 feet +206 upstream of State Route 203. Wilkerson Creek At the Geneva...

  2. Papers Delivered at the Junior/Senior College English Workshop (Hinds Junior College, February 5, 1972) and the Workshop for English Teachers (University of Mississippi, February 12, 1972) and a Research Paper Outline.

    ERIC Educational Resources Information Center

    McPhail, Augustine H., Comp.

    The following are nine papers delivered at the annual workshop for junior and senior college English teachers held at Hinds Jr. College on February 5, 1972: "The Role of Grammar in the Classroom" -Mrs. Elba Patterson; "Grammar in the English Class" -Dr. Gerald Walton; "Creative Writing and Freshman English" Gordon Weaver; "Attitudes Toward the…

  3. Computer Programs for Sun and Moon Illuminance with Contingent Tables and Diagrams

    DTIC Science & Technology

    1987-02-19

    65 31 Oothan 162 61 Bethel 110 33 Safford 86 31 Elba 146 61 Cordova 115 32 San Luis 85 32 Eufaula 158 59 Dfllingham 112 31 Sasabe 88 33 Eutau 147... Apache 92 36 Cave City 86 32 Montgomery 113 35 Bagdad 93 35 Clerksville 87 34 Moutton 115 35 Berry 92 36 Clinton 86 34 Onaonta 109 37 Blttabito 92 35

  4. 77 FR 788 - Southern LNG Company, L.L.C.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-06

    ... Energy Regulatory Commission Southern LNG Company, L.L.C.; Notice of Application Take notice that on December 15, 2011, Southern LNG Company, L.L.C. (SLNG), 569 Brookwood Village, Suite 501, Birmingham... compressor unit at its liquefied natural gas (LNG) terminal located at Elba Island, Georgia...

  5. 75 FR 51989 - Southern LNG Company, L.L.C.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... Energy Regulatory Commission Southern LNG Company, L.L.C.; Notice of Application August 16, 2010. Take notice that on August 4, 2010, Southern LNG Company, L.L.C. (Southern LNG), Post Office Box 2563... with certain facilities located at its liquefied natural gas (LNG) import terminal on Elba Island,...

  6. 76 FR 60357 - Golden Nematode; Removal of Regulated Areas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ... nematode (Globodera rostochiensis) is a destructive pest of potatoes and other solanaceous plants. Potatoes... no longer required. From 1977 until 2010, potato production fields in the townships of Elba and Byron... nematode quarantine. In 2007, there were 13 farms in Genesee County that harvested potatoes. These farms...

  7. What I Learned from the Flood of 1997: Or, Why Archival Class Is Essential.

    ERIC Educational Resources Information Center

    Reinertson-Sand, Mary

    1999-01-01

    Relates the author's experiences of salvaging items following the Grand Forks (North Dakota) flood of 1997. Highlights include restoring home movies, paper documents, and photographs; setting realistic recovery goals; and preserving document copies in other locations. A sidebar describes experiences of the public library in Elba (Alabama) after…

  8. Engineering and Design: Interim Procedure for Specifying Earthquake Motions

    DTIC Science & Technology

    2007-11-02

    Earthquake Engineering, Instituto di Scienza e Techn?.ca delle. Construzioni Politechico di Milano, Piazza da Leonardo da Vinci , 32, 20133 Milano, Italia...Construzioni Politechico di Milano, Piazza da Leonardo da Vinci , 32, 20133 Milano, Italia. 17. Seed, H. B., Murarka, R., Lysmer, J., and Idriss, I. M. 1976

  9. Burst Analysis of Chemically Stimulated Spinal Cord Neuronal Networks Cultured on Microelectrode Arrays

    DTIC Science & Technology

    2007-11-02

    Electronic Engineering, University of Genoa, Italy, 2Telecom Italia S.p.A., Rome, Italy Report Documentation Page Report Date 25 Oct 2001 Report Type N...CNR) , Target project “Biotechnology” and by Telecom Italia S.p.A., protocol 0009989-01 REFERENCES [1] G. W. Gross: “Simultaneous single unit

  10. 3D Crustal Structure of the North-Ligurian Margin from Refraction Tomography S. Simon (1), J.-X. Dessa (1), M.-O. Beslier (1), A. Deschamps (1), N. Béthoux (1), S. Solarino (2), E. Eva (2), F. Sage (1), G. Ferretti (3), C. Eva (3), M. Lelièvre (1), and the GROSMarin Team (1)UNS/UPMC/OCA/INSU-CNRS/IRD, Villefranche-sur-Mer, France (ssimon@geoazur.obs-vlfr.fr), (2)INGV/Dip.Te.Ris, Genova, Italia (3) Univ. Genova/Dip.Te.Ris, Genova, Italia

    NASA Astrophysics Data System (ADS)

    Simon, S.; Dessa, J.; Beslier, M.; Deschamps, A.; Béthoux, N.; Solarino, S.; Eva, E.; Ferretti, G.; Eva, C.; Lelievre, M.

    2010-12-01

    The GROSMarin experiment, held in 2008, investigates the structures of the seismically active North Ligurian rifted margin. An array of 21 Ocean Bottom Seismometers was deployed offshore a region spanning from Nice to Imperia and recorded seismic refraction shots as well as microseismicity for a duration of more than 5 months. It was extended onland by both the regional French and Italian seismic networks and 13 mobile stations that provided an even density of acquisition on- and offshore. With this programme, we aim at characterizing the main structures of this singular margin and adjacent atypical oceanic crust and thick Alpine foreland. We also seek to detect and locate microseismic events that occur regularly, mostly offshore, and that herald rare large events such as the destructive 1887 Imperia earthquake (Mw 6.5) which is the greatest seismic event in the area since at least four hundred years, and whose source and associated tectonics remain poorly understood. We present and discuss some results of our active first arrival travel time tomography that covers the margin and coastal zone and includes a total of ~185,000 picks. The transition from oceanic to continental domains is clearly evidenced as well as an intermediate zone wherein anomalously high velocities are found at the base of the crust. Velocity structures are not found to evidence significant variations along strike and locally fit some published results of 1D logs.

  11. Assessment of terrestrial gamma radiation doses for some Egyptian granite samples.

    PubMed

    El Arabi, A M; Ahmed, N K; Salahel Din, K

    2008-01-01

    External exposures of population to ionising radiation due to naturally occurring radionuclides in sixty-three granite samples from three different locations in south eastern desert of Egypt were considered in this article. Average outdoor gamma dose rates in air were 190, 290 and 330 nGy h(-1) for Elba, Qash Amir and Hamra Dome granites, respectively. The corresponding doses in indoor air are 270, 400 and 470 nGy h(-1), respectively. These average values give rise to annual effective dose (outdoor, indoor and in total) 0.24, 1.4 and 1.6 mSv for Elba granite. For Qash Amir and Hamra Dome granites the corresponding values were 0.35, 2 and 2.3 mSv and 0.41, 2.3 and 2.7 mSv, respectively.

  12. Review of total cross sections and forward scattering parameters at ultra-high energies

    SciTech Connect

    Block, M.M.; White, A.R.

    1991-10-01

    We review the field of the elastic scattering of pp and {bar p}p at the ultra-high energies. The recent total cross section, {sigma}{sub tot}, and {rho}-value results from the Fermilab Tevatron Collider experiments presented at the 4th `Blois` Workshop on Elastic and Diffractive Scattering (Elba, Italy, in May, 1991), allow us a comprehensive overview of the field. 24 refs., 10 figs., 3 tabs.

  13. Review of total cross sections and forward scattering parameters at ultra-high energies

    SciTech Connect

    Block, M.M. . Dept. of Physics and Astronomy); White, A.R. . High Energy Physics Div.)

    1991-10-01

    We review the field of the elastic scattering of pp and {bar p}p at the ultra-high energies. The recent total cross section, {sigma}{sub tot}, and {rho}-value results from the Fermilab Tevatron Collider experiments presented at the 4th Blois' Workshop on Elastic and Diffractive Scattering (Elba, Italy, in May, 1991), allow us a comprehensive overview of the field. 24 refs., 10 figs., 3 tabs.

  14. National Dam Safety Program. Lake Placid Village Dam. (Inventory Number NY 781), Lake Champlain River Basin, Essex County, New York. Phase I Inspection Report,

    DTIC Science & Technology

    1980-09-16

    Village of Lake Placid, Town of North Elba , Essex County, New York. c. Size Classification The maximum height of the dam is approximately 19 feet. The...certain assumptions, based on experience and existing data were used in this analysis and in the determination of the dam’s spillway capacity to pass...Day: Year 5. pparenc use - I. Fish & Wildlife Management 4. Power 2. Recreation 5. Farm * 3. Water Supply 6. No Apparent Use 6. li I. Earth with Aux

  15. JPRS Report, East Europe.

    DTIC Science & Technology

    1991-08-16

    out the dark veins at secret government experiment .... Slusovice, and to show that WE KNOW WHAT IT IS ALL ABOUT. To be completely honest, I do not know... resources worth the entire truth lies, even though I make no secret of my Kcs80, it was necessary to compensate for the deficit. conviction that Eng... Elba . Moreover, we had expensive. In short, in the end he offered us the flag. Some around 15 signed coproduction agreements. For example, time later, he

  16. 7 CFR 51.880 - U.S. Extra Fancy Table.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... dry and brittle; (3) At least yellowish-green in color except for Cardinal, Robin, Exotic, and Beauty...) Ribier, Cardinal, Robin, Exotic, Queen, Italia Muscat, and other similar varieties thirteen-sixteenths...

  17. 7 CFR 51.880 - U.S. Extra Fancy Table.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... dry and brittle; (3) At least yellowish-green in color except for Cardinal, Robin, Exotic, and Beauty...) Ribier, Cardinal, Robin, Exotic, Queen, Italia Muscat, and other similar varieties thirteen-sixteenths...

  18. 7 CFR 51.880 - U.S. Extra Fancy Table.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., Robin, Exotic, and Beauty Seedless varieties. (d) Berries free from: (1) Decay; (2) Waterberry; (3... for varieties as follows: (i) Ribier, Cardinal, Robin, Exotic, Queen, Italia Muscat, and other...

  19. 7 CFR 51.880 - U.S. Extra Fancy Table.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., Robin, Exotic, and Beauty Seedless varieties. (d) Berries free from: (1) Decay; (2) Waterberry; (3... for varieties as follows: (i) Ribier, Cardinal, Robin, Exotic, Queen, Italia Muscat, and other...

  20. 78 FR 72630 - Initiation of Antidumping and Countervailing Duty Administrative Reviews and Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... Shoes Plant Shanghai Ding Ying Printing & Dyeing Co. Ltd..... Shanghai Guoxing Metal Products Co. Ltd... of initiation of the review, will determine, consistent with FAG Italia v. United States, 291...

  1. 75 FR 66349 - Initiation of Antidumping and Countervailing Duty Administrative Reviews

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ... Transport Systems Seet Kamal International Sonal Printers Pvt Ltd. Super Impex Swati Growth Funds Ltd. V & M... determine, consistent with FAG Italia v. United States, 291 F.3d 806 (Fed. Cir. 2002), as...

  2. Gemcitabine and cisplatin versus vinorelbine and cisplatin versus ifosfamide+gemcitabine followed by vinorelbine and cisplatin versus vinorelbine and cisplatin followed by ifosfamide and gemcitabine in stage IIIB-IV non small cell lung carcinoma: a prospective randomized phase III trial of the Gruppo Oncologico Italia Meridionale.

    PubMed

    Gebbia, Vittorio; Galetta, Domenico; Caruso, Michele; Verderame, Francesco; Pezzella, Giuseppe; Valdesi, Matteo; Borsellino, Nicolò; Pandolfo, Giuseppe; Durini, Ernesto; Rinaldi, Massimo; Loizzi, Michele; Gebbia, Nicola; Valenza, Roberto; Tirrito, Maria Lina; Varvara, Francesca; Colucci, Giuseppe

    2003-02-01

    we carried out a phase III randomized trial to compare vinorelbine-cisplatin regimen to gemcitabine-cisplatin regimen, and to a sequential administration of gemcitabine-ifosfamide followed by vinorelbine-cisplatin or the opposite sequence of vinorelbine-cisplatin followed by ifosfamide-gemcitabine according to the 'worst drug rule' hypothesis in patients with locally advanced unresectable stage IIIB or metastatic stage IV non-small cell lung cancer. The primary endpoint was survival parameters, while secondary endpoints included analysis of response rates and toxicity. patients were randomized to receive: (a) gemcitabine 1000 mg/m(2) on days 1, 8 and 15 plus ifosfamide 1500 mg/m(2) on days 8-12 with mesna uroprotection (GI regimen) followed by vinorelbine 25 mg/m(2) on days 1 and 8 plus cisplatin 100 mg/m(2) on day 1 (GI --> VC regimen); (b) the opposite sequence (VC --> GI); (c) vinorelbine plus cisplatin as above described (VC regimen); or (d) gemcitabine 1400 mg/m(2) on days 1 and 8 plus cisplatin 100 mg/m(2) on day 8 (GC regimen). All regimens were given every 4 weeks. All patients were chemotherapy naive and had a ECOG PS 0-2. 400 patients were enrolled into the trial. Interim analysis after inclusion of 243 patients showed that ORR were 19% in the GI --> VC arm, 32% in the inverse sequence arm (CV --> GI), 42% in the VC arm, and 30% in the GC arm. The VC arm was statistically superior over the GI --> VC arm (p = 0.0074), but not over the other regimens. Median TTP was 3.1 months in the GI --> VC arm versus 5.0 months in the VC --> GI arm (p = 0.014). For these reasons the GI --> VC and VC --> GI arm were closed since the 'worst drug rule' hypothesis was rejected. Accrual in the VC and GC arms continued up to 140 and 138 patients respectively. Final ORR were 44% for the VC regimen (4 CR), and 34% for the GC regimen (1 CR). This difference was statistically significant (p = 0.032). OS was 9.0 and 8.2 months, respectively, with no statistically significant difference. The 1-year survival rate was 24 and 20%, respectively for VC and GC regimens. As expected the incidence of phlebitis was higher in the VC arm, while thrombocytopenia, flu-like syndrome and asthenia were more frequent in the GC arm. the results of this trial indicate that the combination of vinorelbine and cisplatin and that of gemcitabine and cisplatin are equivalent in terms of median TTP and OS, although the vinorelbine-cisplatin regimen is associated with a higher ORR. Both regimens may be considered as reference treatments for future studies. Moreover, our data reject the 'worst drug rule' hypothesis of sequential treatments in NSCCL at least with the combination used in this study. Copyright 2002 Elsevier Science Ireland Ltd.

  3. Static and dynamic analyses of the stability of mining wastes (Ravaneti) in the Carrara marble area (Apuan Alps, Italy) / Analiza statyczna i dynamiczna stabilności hałd odpadów górniczych w regionie wydobycia marmurów Carrara (Alpy Apuańskie, Italia)

    NASA Astrophysics Data System (ADS)

    Oreste, Pierpaolo; Soldano, Silvia

    2012-12-01

    The problem of the stability of "ravanetos" (debris piles of mining waste material extracted from the Apuan Alps, Italy) is very relevant, because of the consequences a landslide would have on the people and the existing civil infrastructures throughout the territory. In this work, the stability of two ravanetos that can be considered as representative of those in the Carrara area has been studied: the Polvaccio ravaneto, a recent type of debris pile and the Torrione-Tecchione, an old debris pile at present undergoing re-naturalisation. The study using the LEM (Limit Equilibrium Method) in a static and pseudo-static field, has made it possible to first carry out a back-analysis to define the most probable apparent cohesion and friction angle values of the material that makes up the ravanetos. Subsequently, it was possible to determine the intensity of the seismic wave that would be able to lead the two ravanetos to limit stability conditions and to determine the probability of such a seismic wave occurring in the next 50 years. A more accurate analysis, carried out with a numerical method in the dynamic field, of the most critical condition (the Polvaccio ravaneto) has led to more conservative results (higher safety factors) than those obtained with the LEM. This result allows us to reveal how the LEM can be considered a cautionary instrument to judge the stability of debris piles during a seismic event and that the likelihood of a landslide occurring in the two studied representative ravanetos over the next 50 years is very slim.

  4. Comment on: "Borgia, A., Mazzoldi, A., Brunori, C.A., Allocca, C., Delcroix, C., Micheli, L., Vercellino, A., Grieco, G., 2014. Volcanic spreading forcing and feedback in geothermal reservoir development, Amiata Volcano, Italia. J. Volc. Geoth. Res. 284, 16-31"

    NASA Astrophysics Data System (ADS)

    Barazzuoli, Piero; Bertini, Giovanni; Brogi, Andrea; Capezzuoli, Enrico; Conticelli, Sandro; Doveri, Marco; Ellero, Alessandro; Gianelli, Giovanni; La Felice, Sonia; Liotta, Domenico; Marroni, Michele; Manzella, Adele; Meccheri, Marco; Montanari, Domenico; Pandeli, Enrico; Principe, Claudia; Ruggieri, Giovanni; Sbrana, Alessandro; Vaselli, Orlando; Vezzoli, Luigina

    2015-09-01

    Borgia et al. (2014) illustrated an active volcanic spreading model for the Amiata volcanic area (southern Tuscany, Italy). Although, at first glance, the model may appear appealing, this is not fully supported by the available data and the paper does not take into account their discussion. Accordingly, the supposed negative consequences of the Borgia et al. (2014) model on both contamination of shallow water and geothermal exploitation can likely be regarded as speculative.

  5. First record of the genus Pycnodictya with its subspecies P. galinieri galinieri from Egypt (Orthoptera, Acrididae)

    PubMed Central

    Haggag, Asmaa A.

    2016-01-01

    Abstract The band-winged Pycnodictya galinieri galinieri (Reiche & Fairmaire, 1849) and its genus Pycnodictya Stål, 1873 (Orthoptera: Acrididae: Oedipodinae) are recorded for the first time for the Egyptian fauna. The species was collected from Gabal Elba, in the southeastern corner of Egypt. This record expands the known distributional range of Pycnodictya galinieri towards the north of Africa. Descriptions of the genus and the Egyptian subspecies are given using multiple diagnostic characters. The descriptions are supplemented by drawings and photographs of the specimen collected. It is proposed that the genus Pycnodictya belongs to the tribe Locustini. PMID:27917042

  6. Working group 1: Coronal streamers

    SciTech Connect

    Kopp, R.A.

    1994-04-01

    The working group on colonel streamers convened on the first day of the 2nd SOHO Workshop, which took place in Marciana Marina, Isola d`Elba, 27 September--1 October 1993. Recent progress in streamer observational techniques and theoretical modeling was reported. The contribution of streamers to the mass and energy supply for the solar wind was discussed. Moreover, the importance of thin electric current sheets for determining both the gross dynamical properties of streamers and the fine-scale filamentary structure within streamers, was strongly emphasized. Potential advances to our understanding of these areas of colonel physics that could be made by the contingent of instruments aboard SOHO were pointed out.

  7. Elemental contents in Napoleon's hair cut before and after his death: did Napoleon die of arsenic poisoning?

    PubMed

    Lin, Xilei; Alber, D; Henkelmann, R

    2004-05-01

    Whether or not Napoleon died of arsenic poisoning is an open question on which debate has been active since 1960. This work examined several of his hairs, cut at different times and in different places: two pieces cut the day after his death on the island of St. Helena (1821) and two pieces cut seven years earlier (1814) during his first exile on the island of Elba. INAA results show that all of the samples of Napoleon's hair have an elevated arsenic concentration. These results disfavor the arsenic poisoning theory. Aside from arsenic, 18 other elements are reported, providing additional information for examining the arsenic poisoning theory.

  8. Potential for long-term LNG supply. Final report

    SciTech Connect

    Moncrieff, T.I.; Goldman, D.P.; Jeffries, E.F.; Sherff, J.L.; Wood-Collins, J.C.

    1991-08-01

    Limited foreign liquefaction and U.S. LNG terminal capacity exists before 1993, after which time re-opening of the Cove Point and, later, Elba Island terminals, together with the refurbishment of inefficient Algerian liquefaction plant, permits a major expansion in U.S.-North African LNG trade. Towards 2000 expansion of all four U.S. LNG receiving terminals is technically possible, providing appropriate market, regulatory and environmental signals are received. These expansions will be necessary in order to absorb LNG supply from new sources such as Venezuela and Nigeria.

  9. Numerical reconstruction of trajectory of small-size surface drifter in the Mediterranean sea. Reconstruction of surface drift in the Mediterranean sea

    NASA Astrophysics Data System (ADS)

    Shchekinova, Elena Y.; Kumkar, Yogesh; Coppini, Giovanni

    2016-02-01

    In this study, we addressed the effects of wind-induced drift on Lagrangian trajectories of surface sea objects using high-resolution ocean forecast and atmospheric data. Application of stochastic Leeway model for prediction of trajectories drift was considered for the numerical reconstruction of the Elba accident that occurred during the period 21.06.2009-22.06.2009: a person on an inflatable raft was lost in the vicinity of the Elba Island coast; from the initial position, the person on a raft drifted southwards in the open sea and later he was found on a partially deflated raft during rescue operation. For geophysical forcing, we used high-resolution currents from the Mediterranean Forecasting System and atmospheric wind from the European Centre for Medium-Range Weather Forecasts. To investigate the effect of wind on trajectory behavior, numerical simulations were performed using different categories of drifter-like particles similar to a person on an inflatable raft. An algorithm of spatial clustering was used to differentiate the most probable search areas with a high density of particles. Our results showed that the simulation scenarios using particles with characteristics of draft-limited sea drifters provided better prediction of an observed trajectory in terms of the probability density of particles.

  10. Impact of thermocline and seabed variability on underwater acoustic communications

    NASA Astrophysics Data System (ADS)

    Siderius, Martin; Porter, Michael; Jensen, Finn

    2004-05-01

    Shallow water acoustic communications experiments were conducted near Kauai in July 2003 and near Capraia and Elba Islands in October 2003. All experiments took place in approximately 100-m water depth but the oceanography and seabed types differed significantly. The Kauai site had a reflective seabed that was combined with highly variable oceanographic conditions that led to performance closely tied to source/receiver geometry. The Capraia site also has a reflective seabed but the winter conditions produced a more mixed water column with a weaker and less variable thermocline than Kauai. The Elba site had nearly the same oceanographic conditions as Capraia but the seabed is a highly lossy. In each of these experiments, signals were transmitted over many hours from fixed and moving platforms and were received at multiple ranges and depths using vertical arrays and single hydrophones. Extensive environmental measurements were made simultaneous to the acoustic transmissions (e.g., measurements of the water column temperature structure and surface wave heights). In this paper, the correlation between environmental factors and communications performance will be presented along with the predictions from modeling. The performance of both multi-frequency shift keying (MFSK) and direct sequence spread spectrum (DSSS) signals will be discussed.

  11. Extension of CAVS coarse-grained model to phospholipid membranes: The importance of electrostatics.

    PubMed

    Shen, Hujun; Deng, Mingsen; Zhang, Yachao

    2017-05-15

    It is evident from experiment that electrostatic potential (or dipole potential) is positive inside PC or PE lipid bilayers in the absence of ions. MARTINI coarse-grained (CG) model, which has been widely used in simulating physical properties of lipid bilayers, fails to reproduce the positive value for the dipole potential in the membrane interior. Although the total dipole potential can be correctly described by the BMW/MARTINI model, the contribution from the ester dipoles, playing a nontrivial role in the electrostatic potential across lipid membranes, is neglected by this hybrid approach. In the ELBA CG model, the role of the ester dipoles is considered, but it is overweighed because various atomistic models have consistently shown that water is actually the leading contributor of dipole potential. Here, we present a CG approach by combining the BMW-like water model (namely CAVS model) with the ELBA-like lipid model proposed in this work. Our CG model was designed not only to correctly reproduce the positive values for the dipole potential inside PC and PE lipid bilayers but also to properly balance the individual contributions from the ester dipoles and water, surmounting the limitations of current CG models in the calculations of dipole potential. © 2017 Wiley Periodicals, Inc.

  12. Different Evolutionary Strategies To Conserve Chromatin Boundary Function in the Bithorax Complex

    PubMed Central

    Cleard, Fabienne; Wolle, Daniel; Taverner, Andrew M.; Aoki, Tsutomu; Deshpande, Girish; Andolfatto, Peter; Karch, Francois; Schedl, Paul

    2017-01-01

    Chromatin boundary elements subdivide chromosomes in multicellular organisms into physically independent domains. In addition to this architectural function, these elements also play a critical role in gene regulation. Here we investigated the evolution of a Drosophila Bithorax complex boundary element called Fab-7, which is required for the proper parasegment specific expression of the homeotic Abd-B gene. Using a “gene” replacement strategy, we show that Fab-7 boundaries from two closely related species, D. erecta and D. yakuba, and a more distant species, D. pseudoobscura, are able to substitute for the melanogaster boundary. Consistent with this functional conservation, the two known Fab-7 boundary factors, Elba and LBC, have recognition sequences in the boundaries from all species. However, the strategies used for maintaining binding and function in the face of sequence divergence is different. The first is conventional, and depends upon conservation of the 8 bp Elba recognition sequence. The second is unconventional, and takes advantage of the unusually large and flexible sequence recognition properties of the LBC boundary factor, and the deployment of multiple LBC recognition elements in each boundary. In the former case, binding is lost when the recognition sequence is altered. In the latter case, sequence divergence is accompanied by changes in the number, relative affinity, and location of the LBC recognition elements. PMID:28007886

  13. CALL in a Communicative Context: A Study of Students' Conversation at a Multimedia Workstation.

    ERIC Educational Resources Information Center

    Miceli, Tiziana; Kennedy, Claire

    2000-01-01

    Evaluated the effectiveness of Italia Oggi, a videodisc-based system for intermediate and advanced students of Italian at Griffith University in Australia. Attention was focused on students' behavior in pair work, including talk at the workstation and the collaborative strategies they employed. (Author/VWL)

  14. 77 FR 63905 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... GRID PLC; Portugal Telecom International Finance B.V.; RWE Aktiengesellschaft; TELECOM ITALIA SPA... PLC; Vattenfall Aktiebolag; VEOLIA ENVIRONNEMENT VIVENDI; VODAFONE GROUP PUBLIC LIMITED COMPANY...; ArcelorMittal; BASF SE; Glencore International AG; Henkel AG & Co. KGaA; Koninklijke DSM N.V.;...

  15. The Translation of the CercleS ELP into Italian: A Case Study on the AICLU Version

    ERIC Educational Resources Information Center

    Gori, Federica

    2012-01-01

    The translation into Italian of the "CercleS" European Language Portfolio (ELP) was undertaken by AICLU (Associazione Italiana Centri Linguistici Universitari) and based on the "Common European Framework of Reference for Languages" (CEFR; Council of Europe 2001), translated into Italian for La Nuova Italia Edizioni, and the…

  16. Cultural Representations in Foreign Language Teaching: A Critique of Four BBC Courses.

    ERIC Educational Resources Information Center

    Mar-Molinero, Clare

    1992-01-01

    Examines four well-known BBC language courses, "Deutsch Direkt!""A Vous la France!""Viva Espana," and "Buongiorno Italia!" It is suggested that these courses focus on tourism, stereotyping both learners and the target culture and that the presentation of the cultural materials is unrealistic. (VWL)

  17. ATMOSPHERIC MERCURY BEHAVIOR AT DIFFERENT ALTITUDES AT NY-ALESUND DURING SPRING 2003

    EPA Science Inventory

    Intensive field measurements of atmospheric mercury and related species were carried out in Ny Alesund, Spitsbergen during the spring of 2003 at two altitudes. Measurements were made at the Italian research station Dirigibile Italia (12m a.s.l.) and on the top of Zeppelin Mountai...

  18. ATMOSPHERIC MERCURY BEHAVIOR AT DIFFERENT ALTITUDES AT NY-ALESUND DURING SPRING 2003

    EPA Science Inventory

    Intensive field measurements of atmospheric mercury and related species were carried out in Ny Alesund, Spitsbergen during the spring of 2003 at two altitudes. Measurements were made at the Italian research station Dirigibile Italia (12m a.s.l.) and on the top of Zeppelin Mountai...

  19. Algunos Resumenes

    NASA Astrophysics Data System (ADS)

    1980-03-01

    En una sesion especial celebrada en Ginebra el dia 26 de marzo el Consejo de la ESO aeepto por unanimidad a Italia y Suiza eomo nuevos estados miembros de la organizaeion. Una vez que los proeedimientos necesarios para la ratifieaeion por las Camaras de ambos pafses hayan sido eoneluldos eon exito, podrfan ellos ser asoeiados efectivamente a prineipios dei ario 1981.

  20. Italian Women's Television Coverage and Audience during the 2004 Athens Olympic Games

    ERIC Educational Resources Information Center

    Capranica, Laura; Tessitore, Antonio; D'Artibale, Emanuele; Cortis, Cristina; Casella, Rita; Camilleri, Enrica; Pesce, Caterina

    2008-01-01

    This study aimed at determining the amount of Italian television coverage dedicated to men's and women's sport and the number of male and female viewers during the 2004 Summer Olympic Games. AUDITEL-AGB Nielsen Media Research Italia provided the TV airtime data for the sport events broadcast, which were classified into three categories: men-only,…

  1. The Translation of the CercleS ELP into Italian: A Case Study on the AICLU Version

    ERIC Educational Resources Information Center

    Gori, Federica

    2012-01-01

    The translation into Italian of the "CercleS" European Language Portfolio (ELP) was undertaken by AICLU (Associazione Italiana Centri Linguistici Universitari) and based on the "Common European Framework of Reference for Languages" (CEFR; Council of Europe 2001), translated into Italian for La Nuova Italia Edizioni, and the…

  2. Italian Women's Television Coverage and Audience during the 2004 Athens Olympic Games

    ERIC Educational Resources Information Center

    Capranica, Laura; Tessitore, Antonio; D'Artibale, Emanuele; Cortis, Cristina; Casella, Rita; Camilleri, Enrica; Pesce, Caterina

    2008-01-01

    This study aimed at determining the amount of Italian television coverage dedicated to men's and women's sport and the number of male and female viewers during the 2004 Summer Olympic Games. AUDITEL-AGB Nielsen Media Research Italia provided the TV airtime data for the sport events broadcast, which were classified into three categories: men-only,…

  3. CALL in a Communicative Context: A Study of Students' Conversation at a Multimedia Workstation.

    ERIC Educational Resources Information Center

    Miceli, Tiziana; Kennedy, Claire

    2000-01-01

    Evaluated the effectiveness of Italia Oggi, a videodisc-based system for intermediate and advanced students of Italian at Griffith University in Australia. Attention was focused on students' behavior in pair work, including talk at the workstation and the collaborative strategies they employed. (Author/VWL)

  4. Adversarial Intent Modeling Using Embedded Simulation and Temporal Bayesian Knowledge Bases

    DTIC Science & Technology

    2009-04-01

    Ptolemy II framework, and • Agent-based modeling enabled by Telecom Italia Lab’s open Java Agent Development (JADE) framework.1...status = degraded ELSE: status = active JADE OAT Ptolemy II Transforms Califon (Country) Proc. of SPIE Vol. 7348 73480E-5 5

  5. Cultural Representations in Foreign Language Teaching: A Critique of Four BBC Courses.

    ERIC Educational Resources Information Center

    Mar-Molinero, Clare

    1992-01-01

    Examines four well-known BBC language courses, "Deutsch Direkt!""A Vous la France!""Viva Espana," and "Buongiorno Italia!" It is suggested that these courses focus on tourism, stereotyping both learners and the target culture and that the presentation of the cultural materials is unrealistic. (VWL)

  6. Savoia seaplane S.55 : military or commercial

    NASA Technical Reports Server (NTRS)

    1927-01-01

    The S.55 is a two engine twin hull seaplane built by Societa Idrovolanti Alta Italia (Seaplane Company of Upper Italy). The S.55 (Santa Maria) is to be used for an around the world flight In 1927. It will have a useful load of 7,500 lbs. and a cruising speed of 100 MPH.

  7. A Comparison of Structural Data and Seismic Images For Low-Angle Normal Faults in the Northern Apennines (Central Italy): Constraints on Geometry and Activity

    NASA Astrophysics Data System (ADS)

    Collettini, C.; Barchi, M. R.

    2001-12-01

    During the last 20 Myr extensional tectonics in the Northern Apennines have moved from the Tyrrhenian sea toward east. Much of the extension is due to low-angle east-dipping normal faults now exhumed in the Tyrrhenian islands and Tuscany, while still accommodating deformation in the Apenninic chain (Umbria region 200 km eastward). This tectonic framework provide an example where exhumed structures can be compared with active extensional structures and processes affecting the Umbria region. It is here proposed the case study of two of these low angle normal faults, the Zuccale fault (Zf), cropping out in the Elba island and the Altotiberina fault (ATF) mainly detected by seismic profiles crossing the Umbria region. The Zf in the eastern part of the Elba island juxtaposes along a gently ( ~ 10° ) eastward dipping contact, the Upper Cretaceous Helminthoid flysch in its hangingwall over the Permian-Triassic (?) phyllitic basement in its footwall. Structural analysis of the brittle structures that characterise the fault zone has been used to constraint the state of stress under which the fault slipped. From the N-S trending vertical vein system perpendicular to the slickenlines of the fault plane and from the Andersonian normal faults present within the fault gouge, some of them rotated according to a top to the east movement, we infer that (1) the maximum principal stress was sub vertical during the fault activity (2) the fault accommodate slip under low values of differential stress and at dips similar to its present flat geometry (3) local fluid overpressures were attained during the fault activity favoured by a thick fault gouge. The geological scenario described in the Elba island shows similarities with the active deformation of the Umbria region. Seismic profiles crossing this area matched with surface geology highlight the presence of an east-dipping low-angle ( ~ 20° ) normal fault, the Altotiberina fault (ATF), and antithetic seismogenic structures bounding

  8. Reply to: Barazzuoli P., Bertini G., Brogi A., Capezzuoli E., Conticelli S., Doveri M., Ellero A., Gianelli G., La Felice S., Liotta D., Marroni M., Manzella A., Meccheri M., Montanari D., Pandeli E., Principe C., Ruggieri R., Sbrana A., Vaselli V., Vezzoli L., 2015. COMMENT ON: "Borgia, A., Mazzoldi, A., Brunori, C.A., Allocca, C., Delcroix, C., Micheli, L., Vercellino, A., Grieco, G., 2014. Volcanic spreading forcing and feedback in geothermal resorvoir development, Amiata Volcano, Italia. J. Volc. Geoth. Res. 284, 16-31". Journal of Volcanology and Geothermal Research, this issue

    NASA Astrophysics Data System (ADS)

    Borgia, Andrea; Mazzoldi, Alberto; Brunori, Carlo Alberto; Allocca, Carmine; Delcroix, Carlo; Micheli, Luigi; Vercellino, Alberto; Grieco, Giovanni

    2015-09-01

    The volcanic spreading model by Borgia et al. (2014) is accurate in describing the extensional structures found on the edifice and the radial compressional structures existing all around the base of Amiata Volcano. Volcanic conduits, extensional structures, and direct contact between the volcanic rocks and the Tuscan Units, constitute the hydraulic connection between the potable fresh-water aquifer contained in the volcanites and the underlying hydrothermal system. Therefore, gaseous phases tend to flow upward (particularly through faults) carrying pollutants into the freshwater aquifer, while the freshwater recharges (also through primary permeability) the exploited geothermal fields.

  9. Aragonite precipitation induced by anaerobic oxidation of methane in shallow-water seeps, Tyrrhenian Sea, Italy

    NASA Astrophysics Data System (ADS)

    Wiedling, Johanna; Kuhfuß, Hanna; Lott, Christian; Böttcher, Michael E.; Lichtschlag, Anna; Wegener, Gunter; Deusner, Christian; Bach, Wolfgang; Weber, Miriam

    2014-05-01

    In the shallow-water organic-poor silicate sands off the West coast of Elba, Italy, we found aragonite precipitates within a radius of 10 cm to methane seeps in 20 - 40 cm sediment depth. The shallow seep site was mapped by SCUBA diving and in an area of 100 m2 nine gas emission spots were observed. The gas emission, containing 73 Vol. % methane, was measured to be 0.72 L m-2 d-1. Findings of anaerobic methane oxidizing archea (ANME 1, 2, 2a, 2b) and sulphate reducing bacteria (SRB) as well as in vitro rate measurements of anaerobic oxidation of methane (AOM) with a maximum of 67 ± 7 nmol CH4 cm-3 d-1 led to the hypothesis that carbonate precipitation is coupled to these microbial processes. Porewater analysis showed elevated concentrations of dissolved inorganic carbon (DIC) (up to 15.5 mmol L-1) and hydrogen sulfide (up to 6.6 mmol L-1). The presence of bicarbonate and the ambient temperature (14 - 25 ° C) facilitate the precipitation of needle-shaped aragonite. Oxygen isotope compositions of the mineral are consistent with the ambient temperatures and may indicate a recent diagenetic formation of this mineral. Although precipitation should not be preserved in these sandy permeable sediments, influenced by seasonality, wave action, and fluid flow, we found up to 10-50 cm3 irregular pieces of cemented sand grains, very often encrusting dead seagrass rhizomes. Commonly known carbonate structures, especially from the deep sea, are chimneys, mounds, hardgrounds and nodules. These structures are well known from seep and vent sites, usually showing the same range of stable carbon isotope fractionation as the escaping methane. The permeable sediment at the Elba site possibly allows the gas to frequently change its pathway to the sediment surface and thus precipitation can occure at several spots and more irregular than in the reported sites. Preservation of precipitates, however, requires sufficient authigenic aragonite to be formed before fluid dynamics changed the

  10. A Structured and Unstructured grid Relocatable ocean platform for Forecasting (SURF)

    NASA Astrophysics Data System (ADS)

    Trotta, Francesco; Fenu, Elisa; Pinardi, Nadia; Bruciaferri, Diego; Giacomelli, Luca; Federico, Ivan; Coppini, Giovanni

    2016-11-01

    We present a numerical platform named Structured and Unstructured grid Relocatable ocean platform for Forecasting (SURF). The platform is developed for short-time forecasts and is designed to be embedded in any region of the large-scale Mediterranean Forecasting System (MFS) via downscaling. We employ CTD data collected during a campaign around the Elba island to calibrate and validate SURF. The model requires an initial spin up period of a few days in order to adapt the initial interpolated fields and the subsequent solutions to the higher-resolution nested grids adopted by SURF. Through a comparison with the CTD data, we quantify the improvement obtained by SURF model compared to the coarse-resolution MFS model.

  11. The culturable mycobiota of Flabellia petiolata: First survey of marine fungi associated to a Mediterranean green alga.

    PubMed

    Gnavi, Giorgio; Garzoli, Laura; Poli, Anna; Prigione, Valeria; Burgaud, Gaëtan; Varese, Giovanna Cristina

    2017-01-01

    Algae-inhabiting marine fungi represent a taxonomically and ecologically interesting group of microorganisms still largely neglected, especially in temperate regions. The aim of this study was to isolate and to identify the culturable mycobiota associated with Flabellia petiolata, a green alga frequently retrieved in the Mediterranean basin. Twenty algal thalli were collected from two different sampling sites in the Mediterranean Sea (Elba Island, Italy). A polyphasic approach showed the presence of a relevant alga-associated mycobiota with 64 taxa identified. The fungal isolates belonged mainly to Ascomycota (61 taxa), while only three Basidiomycota were detected. The phylogenetic position of sterile mycelia and cryptic taxa, inferred on the basis of LSU partial region, highlighted the presence of putative new phylogenetic lineages within Dothideomycetes and Sordariomycetes. This work represents the first quali-quantitative analysis of the culturable mycobiota associated to a green alga in the Mediterranean Sea.

  12. Editorial for the Proceedings of the Vienna Conference on Instrumentation 2016

    NASA Astrophysics Data System (ADS)

    2017-02-01

    The 14th Vienna Conference on Instrumentation took place in Vienna from February 15 to 19, 2016. The conferences in this series, which was originally founded as the "Vienna Wire Chamber Conference" in 1978, are held in Vienna every three years, alternating with two other major international conferences in the field, the ;Pisa Meeting on Advanced detectors; on the island of Elba in Italy and the ;International Conference on Instrumentation for Colliding Beam Physics; in Novosibirsk, Russia. The 2016 Conference was structured in the way that was successfully introduced in the preceding VCI conference in 2013: several parallel sessions covered highly specialized topics while plenaries were maintained for topics of general interest. The meetings again took place in the pleasant setting of the Department of Electrical Engineering of the Vienna University of Technology (TU Wien), close to the city center and the University's other buildings.

  13. Editorial for the Proceedings of the Vienna Conference on Instrumentation 2016

    NASA Astrophysics Data System (ADS)

    No Author

    2017-02-01

    The 14th Vienna Conference on Instrumentation took place in Vienna from February 15 to 19, 2016. The conferences in this series, which was originally founded as the "Vienna Wire Chamber Conference" in 1978, are held in Vienna every three years, alternating with two other major international conferences in the field, the "Pisa Meeting on Advanced detectors" on the island of Elba in Italy and the "International Conference on Instrumentation for Colliding Beam Physics" in Novosibirsk, Russia. The 2016 Conference was structured in the way that was successfully introduced in the preceding VCI conference in 2013: several parallel sessions covered highly specialized topics while plenaries were maintained for topics of general interest. The meetings again took place in the pleasant setting of the Department of Electrical Engineering of the Vienna University of Technology (TU Wien), close to the city center and the University's other buildings.

  14. X-ray properties of normal galaxies

    NASA Technical Reports Server (NTRS)

    Fabbiano, G.

    1993-01-01

    In this paper I will first review briefly the results of the X-ray observations of early-type galaxies with the HEAO 2 (Eisnstein) satellite, published in the past ten years. I will then concentrate on more recent results stemming from a systematic re-analysis of the Einstein galaxy database, and I will also report on some very preliminary ROSAT results. Parts of this talk were given at the ESO Elba meeting on early-type galaxies in May 1992 and therefore there is a considerable overlap between this paper and that in the proceedings of that meeting. Some of this material was also reviewed by Fabbiano and Kim (1992) and Fabbiano (1992b).

  15. Future Ground-Based Solar System Research: a Prospective Workshop Summary

    NASA Astrophysics Data System (ADS)

    Boehnhardt, H.; Käufl, H. U.

    2009-09-01

    The article tries to provide a perspective summary of the planetary science to be performed with future extremely large telescopes (ELTs) as an outcome of the workshop on ‘Future Ground-based Solar System Research: Synergies between Space Probes and Space Telescopes’ held on 8-12 September 2008 in Portoferraio on Isola d’ Elba, Italy. It addresses science cases on solar system objects that might challenge the capabilities of ELTs and that provide a major step forward in the knowledge and understanding of planetary system objects per se and all populations. We also compile high-level requirements for such telescopes and their instrumentation that should enable successful ELT usage for research on objects in the Solar System, the ‘disturbing foreground to real astronomy’.

  16. The culturable mycobiota of Flabellia petiolata: First survey of marine fungi associated to a Mediterranean green alga

    PubMed Central

    Garzoli, Laura; Poli, Anna; Prigione, Valeria; Burgaud, Gaëtan; Varese, Giovanna Cristina

    2017-01-01

    Algae-inhabiting marine fungi represent a taxonomically and ecologically interesting group of microorganisms still largely neglected, especially in temperate regions. The aim of this study was to isolate and to identify the culturable mycobiota associated with Flabellia petiolata, a green alga frequently retrieved in the Mediterranean basin. Twenty algal thalli were collected from two different sampling sites in the Mediterranean Sea (Elba Island, Italy). A polyphasic approach showed the presence of a relevant alga-associated mycobiota with 64 taxa identified. The fungal isolates belonged mainly to Ascomycota (61 taxa), while only three Basidiomycota were detected. The phylogenetic position of sterile mycelia and cryptic taxa, inferred on the basis of LSU partial region, highlighted the presence of putative new phylogenetic lineages within Dothideomycetes and Sordariomycetes. This work represents the first quali-quantitative analysis of the culturable mycobiota associated to a green alga in the Mediterranean Sea. PMID:28426712

  17. Towards a continuous recording of earth magnetic field reversals by secondary pyrrhotite pTRMs

    NASA Astrophysics Data System (ADS)

    Wehland, F.; Alt-Epping, U.; Crouzet, C.; Appel, E.

    2003-04-01

    Partial Thermoremanent Magnetisations (pTRMs) by secondary pyrrhotite, recorded during fast cooling in contact metamorphic limestone, were used for the first time to test the ability of recording Earth Magnetic Field (EMF)Reversals within a single sample. For this purpose, samples from marly limestones were taken in the vicinity of intrusions from the Tethyan Himalaya (Manaslu), Elba Island, Toscany and the Isle of Skye. For each location pyrrhotite was identified by the unblocking spectra of the NRM and the thermal demagnetisation of IRM. Thellier-Thellier-tests of a laboratory TRMs incl. MD checks have proven that pyrrhotite particles are predominantly in the SD range and, therefore, are able to record independent pTRMs. Additionally FORC analysis have shown that the magnetic particles do not interact. The process of pyrrhotite formation has been investigated by petrological experiment indicating a rapid cristallisation close to pyrite. In selected sites from Elba Island thermal demagnetisation of the NRM reveals a reversed low temperature (150°C-250°C) and a normal high temperature (290°C-320°C) component. The angle between the two components is ~150° with a gradual transition over an average temperature range of ~40°C during unblocking. Positive fold tests on the low (k=10.2 ; alpha(95)=11.0) and the high temperature component (k=20.4 ; alpha(95)=8.4) evidence that the NRM is secondary and likely of thermoremanent origin. A scenario where the low temperature component is caused by a second heating event is unlikely due to the gradual transition of the NRM and the lack of evidence for a multiple intrusion or other thermal event. An estimation of the time enveloped in the transitional temperature range retrieved by thermal modelling of the contact metamorphism lies at 10 kyr. This time span is comparable with an average value for EMF reversals.

  18. Payload Processing for Mice Drawer System

    NASA Technical Reports Server (NTRS)

    Brown, Judy

    2007-01-01

    Experimental payloads flown to the International Space Station provide us with valuable research conducted in a microgravity environment not attainable on earth. The Mice Drawer System is an experiment designed by Thales Alenia Space Italia to study the effects of microgravity on mice. It is designed to fly to orbit on the Space Shuttle Utilization Logistics Flight 2 in October 2008, remain onboard the International Space Station for approximately 100 days and then return to earth on a following Shuttle flight. The experiment apparatus will be housed inside a Double Payload Carrier. An engineering model of the Double Payload Carrier was sent to Kennedy Space Center for a fit check inside both Shuttles, and the rack that it will be installed in aboard the International Space Station. The Double Payload Carrier showed a good fit quality inside each vehicle, and Thales Alenia Space Italia will now construct the actual flight model and continue to prepare the Mice Drawer System experiment for launch.

  19. Implementing the KLT

    NASA Astrophysics Data System (ADS)

    Montebugnoli, Stelio

    SETI-Italia is an observing program led by the INAF-IRA (Istituto Nazionale di Astrofisica - Istituto di Radioastronomia). At present, Italy is the only European country conducting a SETI (Search for Extraterrestrial Intelligence) program. Occasional SETI searches may be conducted at the Nanacy French Kraus type radiotelescope and some artificial signals are sometime transmitted with the 70-m dish in the Ukraine. Outside Europe, continuous SETI programs are conducted in the USA, Australia and Argentina.

  20. European Science Notes Information Bulletin Reports on Current European/ Middle Eastern Science

    DTIC Science & Technology

    1989-03-01

    nimize the execution time of the program. In almost all When using pipeline operation in the coarse-grained applications, only a portion of the...K. in Na(’l by small-,ngle x-ray scatterii-,. In addition, they Driss-Khodja (Universit d’()ran-cs-Scnia, Algeria ) cal- found that the Na particles...million) the 54 surveyed professional organiza- Telettra, Italtel, IBM Italia , Honeywell and 70 researchers, is studying the devel- tions represented

  1. Fortresses and Icebergs: The Evolution of the Transatlantic Defense Market and the Implications for U.S. National Security Policy. Volume 1: Study Findings and Recommendations

    DTIC Science & Technology

    2009-01-01

    rationale and the roadmap for our engagement with Europe on defense markets in support of our mutual security objectives. Dr. Jacques S. Gansler Roger C...Acquired by Northrop through Litton Industries. Leading producer of military and space navigation systems. Northrop Grumman Sperry Marine GmbH...when it acquired Litton Industries. Its subsidiaries Northrop Grumman Italia, Northrop Grumman LITEF and Northrop Grumman Sperry Marine, are all

  2. JPRS Report, Science & Technology, Europe, Economic Competitiveness.

    DTIC Science & Technology

    1991-08-09

    Countries [C. Chartier ; Paris LE MONDE, 20 Jun 91] 38 Italian Companies Form Advanced Robotics Consortium [Milan ITALIA OGGI, 22 May 91] 38...can also involve a pooling of research programs or the establishment of common standards," said French Minister of Industry Roger Fauroux, during the...Countries 91WS0410C Paris LE MONDE in French 20 Jun 91 [Article by Christian Chartier : tries Invited to Join Eureka"] ’East European Coun- [Text] The

  3. 100 years from the birth of prof. František Běhounek

    NASA Astrophysics Data System (ADS)

    Jech, Č.

    1999-01-01

    It was the scholarship in the Curie laboratory, which directed Běhounek's scientific interest to radioactivity and nuclear physics, and his participation in the Italia expedition to the North Pole, which revealed his talent as storyteller and writer. Běhounek's role and significance as scientist, writer of popular science books and romantic sci-fi stories for children are reviewed in this historical note.

  4. An International Survey of Industrial Applications of Formal Methods. Volume 2. Case Studies

    DTIC Science & Technology

    1993-09-30

    Display and Information System (CDIS) I which forms part of this program. CDIS forms a vital component of the data entry and display equipment used by...SA, Inisel Espacio SA, Lloyd’s Register of Shipping, Matra Transportation SA, Space Software Italia SpA, STC Technology Ltd. (now part of BNR Europe...principles are mostly unchanged. The software is, of course, entirely new. The safety principles ( Vital coded processor) are that of SACEM. The

  5. Antiproliferative and apoptotic effects triggered by Grape Seed Extract (GSE) versus epigallocatechin and procyanidins on colon cancer cell lines.

    PubMed

    Dinicola, Simona; Cucina, Alessandra; Pasqualato, Alessia; D'Anselmi, Fabrizio; Proietti, Sara; Lisi, Elisabetta; Pasqua, Gabriella; Antonacci, Donato; Bizzarri, Mariano

    2012-01-01

    Grape seed extract has been proven to exert anticancer effects on different tumors. These effects are mainly ascribed to catechin and procyanidin content. Analytical studies demonstrated that grape seed extract composition is complex and it is likely other components could exert biological activities. Using cell count and flow cytometry assays, we evaluated the cytostatic and apoptotic effects produced by three different grape seed extracts from Italia, Palieri and Red Globe cultivars, on Caco2 and HCT-8 colon cancer cells. These effects were compared to those induced by epigallocatechin and procyanidins, alone or in association, on the same cell lines. All the extracts induced growth inhibition and apoptosis in Caco2 and HCT-8 cells, along the intrinsic apoptotic pathway. On both cell lines, growth inhibition induced by Italia and Palieri grape seed extracts was significantly higher than that it has been recorded with epigallocatechin, procyanidins and their association. In Caco2 cells, the extract from Red Globe cultivar was less effective in inducing growth inhibition than procyanidins alone and in association with epigallocatechin, whereas, in HCT-8 cells, only the association of epigallocatechin and procyanidins triggers a significant proliferation decrease. On both cell lines, apoptosis induced by Italia, Palieri and Red Globe grape seed extracts was considerably higher than has been recorded with epigallocatechin, procyanidins and their association. These data support the hypothesis by which other compounds, present in the grape seed extracts, are likely to enhance the anticancer effects.

  6. [Tarantism in Spain in the eighteen century: latrodectism and suggestion].

    PubMed

    Corral-Corral, I; Corral-Corral, C

    2016-10-16

    Introduccion. El tarantismo es la enfermedad producida por la picadura de la tarantula, en la que la musica de la tarantela desencadena un baile involuntario. Se conoce en Italia desde el siglo XVI. Objetivo. Analizar el tarantismo descrito en España a finales del siglo XVIII, atendiendo especialmente a sus aspectos neurologicos, y proponer su explicacion medica y psicopatologica. Desarrollo. En 1782 hubo una epidemia de afectados por picadura de tarantula en España. Medicos españoles describieron correctamente los efectos clinicos, identicos a los provocados por la picadura de la araña viuda negra (Latrodectus tredecimguttatus), identificada en la epoca como tarantula. Los casos descritos por Francisco Xavier Cid curaban con el baile involuntario provocado por la tarantela, como se describia en Italia desde el siglo XVI. Interpretamos el efecto curativo de este baile en España como un fenomeno de sugestion. En los pacientes españoles no se producian los trastornos del comportamiento, las recidivas periodicas ni la afectacion colectiva descritos por autores italianos, y que sugieren un fenomeno histerico, probablemente continuacion de la mania danzante de la Edad Media. Conclusiones. El tarantismo descrito en España en el siglo XVIII incluye dos fenomenos distintos: los sintomas sistemicos producidos de la mordedura de la tarantula, que es en realidad un latrodectismo, y el efecto curativo de la tarantela, lo cual se explica por un fenomeno de sugestion. Los trastornos psiquicos falsamente asociados a la picadura de la tarantula observados en Italia, de origen histerico, no estuvieron presentes en los casos españoles de tarantismo del siglo XVIII.

  7. Avionic Architectures for Space Exploration Missions

    NASA Astrophysics Data System (ADS)

    Tramutola, Antonio; Martelli, Andrea; Caramia, Maurizio

    2011-08-01

    The paper presents the activities which are in progress in Thales Alenia Space Italia, founded by the internal research, in parallel with several ESA studies, and related to the definition and characterization of an avionic architecture suitable for the future space exploration missions. A significant capability is required both in term of computing power and of communication bandwidth among all the remote terminals belonging to the on-board avionic. The paper focuses on the on-board computer architecture and on the communication links and introduces the avionic demonstrator that has been set up in TAS-I to explore and test the different architectural solutions.

  8. A TT&C Performance Simulator for Space Exploration and Scientific Satellites - Architecture and Applications

    NASA Astrophysics Data System (ADS)

    Donà, G.; Faletra, M.

    2015-09-01

    This paper presents the TT&C performance simulator toolkit developed internally at Thales Alenia Space Italia (TAS-I) to support the design of TT&C subsystems for space exploration and scientific satellites. The simulator has a modular architecture and has been designed using a model-based approach using standard engineering tools such as MATLAB/SIMULINK and mission analysis tools (e.g. STK). The simulator is easily reconfigurable to fit different types of satellites, different mission requirements and different scenarios parameters. This paper provides a brief description of the simulator architecture together with two examples of applications used to demonstrate some of the simulator’s capabilities.

  9. [Pharmaceutic earthenware of South-West France].

    PubMed

    Charlot, Colette

    2002-01-01

    Medical school and pharmacists renown, the potters presence (traditional work of Languedoc region, rich in clay), financial support from Languedoc governors that De Montmorency, can explain the pharmaceutical earthenware of XVIth century. The workshops of Nîmes, Montpellier or Narbonne are along the first primary centers of this topic. It's interesting to note in this area, the crossing of Spain and Italia. This give the production originality that was disseminate by Beaucaire trade fair. But the lack of sign up on "albarelli", on pots, let a doubt about their original workshop source.

  10. CANOPEN Controller IP Core

    NASA Astrophysics Data System (ADS)

    Caramia, Maurizio; Montagna, Mario; Furano, Gianluca; Winton, Alistair

    2010-08-01

    This paper will describe the activities performed by Thales Alenia Space Italia supported by the European Space Agency in the definition of a CAN bus interface to be used on Exomars. The final goal of this activity is the development of an IP core, to be used in a slave node, able to manage both the CAN bus Data Link and Application Layer totally in hardware. The activity has been focused on the needs of the EXOMARS mission where devices with different computational performances are all managed by the onboard computer through the CAN bus.

  11. Evolving Arms Transfer Rationales: The Case of Italy

    DTIC Science & Technology

    1987-06-01

    began to 5 Libro Bianco-La Difesa, 1977, 57-92. 6 1bid. 23 reconstitute and reequip her armed forces. The 1950’s were tumultuous for the activity in...discussion of the early arms trade in Italy. 8 La Difesa-- Libro Bianco, Ministero della Difesa d’Italia, 1985. 74. 24 in recognizing the problem, the... Libro Bianco, p.xiv. This quote is a portion of the introduction to the White Book written by the Minister of Defense, Giovanni Spadolini. 31 however

  12. Late Miocene remagnetization within the internal sector of the Northern Apennines, Italy

    USGS Publications Warehouse

    Aiello, I.W.; Hagstrum, J.T.; Principi, G.

    2004-01-01

    Paleomagnetic and geologic evidence indicates that Upper Jurassic radiolarian cherts of both the Tuscan Cherts Formation (continental margin, Tuscan Units) and the Monte Alpe Cherts Formation (oceanic crust, Ligurian Units) were remagnetized during Miocene orogenesis of the Northern Apennines of Italy. Characteristic overprint magnetizations with reversed polarities have been found over a large area within the internal sector of the Northern Apennines, including eastern Liguria, Elba Island and the Thyrrenian margin, and west of the Middle Tuscan Ridge. The reversed-polarity overprint (average direction: D=177??, I=-52??, ??95=15??) was most likely acquired during Late Miocene uplift and denudation of the orogenic chain, and thermochemical remagnetization was a probable consequence of increased circulation of orogenic fluids. Similarly, mostly reversed-polarity directions of magnetization have been found by other workers in overlying post-orogenic Messinian sediments (D=177??, I=-57??, ??95=3??), which show little counterclockwise (CCW) vertical-axis rotation with respect to stable Europe (-8??5??). The Monte Alpe Cherts sampled at sites in the external sector of the Northern Apennines, close to major tectonic features, have normal- polarity overprint directions with in situ W-SW declinations. Since the overlying post-orogenic Messinian sediments have not been substantially rotated about vertical axes, the evidence points to an earlier,pre-Late Miocene remagnetization in the external parts of the orogenic chain. ?? 2004 Elsevier B.V. All rights reserved.

  13. Experimental evaluation of magnetic interaction in pyrrhotite bearing samples

    NASA Astrophysics Data System (ADS)

    Wehland, F.; Stancu, A.; Rochette, P.; Dekkers, M. J.; Appel, E.

    2005-12-01

    Pyrrhotite bearing metamorphic limestones have recently experienced an increasing relevance in paleomagnetic research. Simple univectorial remanences document the metamorphic uplift, whereas more complex multicomponent pTRMs may constrain its age. For a successful application of the latter, it is important to estimate the degree of magnetic interactions to ensure the additivity of individual pTRM segments. We therefore have subjected the sized dispersed suite (<5-250 μm) of TTE pyrrhotite to FORC analysis and compared the result with remanence-based parameters like the Δ M or the irreversible susceptibility. This is used as a basis to evaluate the response of marly limestone samples from regionally metamorphic areas (Bourg d'Oisans, France) and contact-metamorphic aureoles (Elba, Italy; Skye, Scottland; Manaslu area, Nepal) to these techniques. The results show that the techniques are able to estimate the nature and - to a certain degree - the intensity of the magnetic interaction. The different dominant magnetic states of the assemblage can also be unravelled as well. Based on the remanence measurements of the TTE samples, a relationship between grain-size and the irreversible susceptibility is established in order to estimate the mean grain-size fraction in natural particle distribution.

  14. An Early Cretaceous garnet pressure-temperature path recording synconvergent burial and exhumation from the hinterland of the Sevier orogenic belt, Albion Mountains, Idaho

    NASA Astrophysics Data System (ADS)

    Kelly, Eric D.; Hoisch, Thomas D.; Wells, Michael L.; Vervoort, Jeffrey D.; Beyene, Mengesha A.

    2015-08-01

    Rocks may undergo complex pressure-temperature ( P- T) histories during orogenesis in response to alternating episodes of synconvergent burial and exhumation. In this study, chemical zoning in garnets combined with textural and chemical evidence from the schist of Willow Creek in the Albion Mountains of south-central Idaho (USA), reveals a complex P- T path during the early stages of Sevier orogenesis. The distribution of quartz inclusions combined with internal resorption features establishes a hiatus in garnet growth. Chemical zoning was simulated using a G-minimization approach to yield a P- T path consisting of three distinct pressure changes during increasing temperature, defining an "N" shape. Lu-Hf isochron ages from multiple garnet fractions and whole-rock analyses in two samples are 132.1 ± 2.4 and 138.7 ± 3.5 Ma. The samples were collected from the hanging wall of the Basin-Elba thrust fault and yielded results similar to those previously obtained from the footwall. This leads to several conclusions: (1) Both the hanging wall and footwall experienced the same metamorphic event, (2) the paths document a previously unrecognized crustal thickening and synorogenic extension cycle that fills an important time gap in the shortening history of the Sevier retroarc, suggesting progressive eastward growth of the orogen rather than a two-stage history, and (3) episodes of extensional exhumation during protracted convergent orogenesis are increasingly well recognized and highlight the dynamic behavior of orogenic belts.

  15. All-atom/coarse-grained hybrid predictions of distribution coefficients in SAMPL5.

    PubMed

    Genheden, Samuel; Essex, Jonathan W

    2016-11-01

    We present blind predictions submitted to the SAMPL5 challenge on calculating distribution coefficients. The predictions were based on estimating the solvation free energies in water and cyclohexane of the 53 compounds in the challenge. These free energies were computed using alchemical free energy simulations based on a hybrid all-atom/coarse-grained model. The compounds were treated with the general Amber force field, whereas the solvent molecules were treated with the Elba coarse-grained model. Considering the simplicity of the solvent model and that we approximate the distribution coefficient with the partition coefficient of the neutral species, the predictions are of good accuracy. The correlation coefficient, R is 0.64, 82 % of the predictions have the correct sign and the mean absolute deviation is 1.8 log units. This is on a par with or better than the other simulation-based predictions in the challenge. We present an analysis of the deviations to experiments and compare the predictions to another submission that used all-atom solvent.

  16. A simple and transferable all-atom/coarse-grained hybrid model to study membrane processes.

    PubMed

    Genheden, Samuel; Essex, Jonathan W

    2015-10-13

    We present an efficient all-atom/coarse-grained hybrid model and apply it to membrane processes. This model is an extension of the all-atom/ELBA model applied previously to processes in water. Here, we improve the efficiency of the model by implementing a multiple-time step integrator that allows the atoms and the coarse-grained beads to be propagated at different timesteps. Furthermore, we fine-tune the interaction between the atoms and the coarse-grained beads by computing the potential of mean force of amino acid side chain analogs along the membrane normal and comparing to atomistic simulations. The model was independently validated on the calculation of small-molecule partition coefficients. Finally, we apply the model to membrane peptides. We studied the tilt angle of the Walp23 and Kalp23 helices in two different model membranes and the stability of the glycophorin A dimer. The model is efficient, accurate, and straightforward to use, as it does not require any extra interaction particles, layers of atomistic solvent molecules or tabulated potentials, thus offering a novel, simple approach to study membrane processes.

  17. Predicting Partition Coefficients with a Simple All-Atom/Coarse-Grained Hybrid Model.

    PubMed

    Genheden, Samuel

    2016-01-12

    The solvation free energy is an essential quantity in force field development and in numerous applications. Here, we present the estimation of solvation free energies in polar (water, hexanol, octanol, and nonanol) and in apolar (hexane, octane, and nonane) media. The estimates are produced using molecular dynamics simulations employing a simple all-atom/coarse-grained hybrid model (AA/ELBA) and are therefore very efficient. More than 150 solutes were taken from the Minnesota solvation database and represent small, organic molecules. The mean absolute deviation for the different solvents ranges between 2.0 and 4.1 kJ/mol, and the correlation coefficient ranges between 0.78 and 0.99, indicating that the predictions are accurate. Outliers are identified, and potential avenues for improvements are discussed. Furthermore, partition coefficients between water and the organic solvents were estimated, and the percentage of the predictions that has the correct sign ranges between 74% (for octane) and 92% (for octanol and hexanol). Finally, membrane/water partition coefficients are replaced with hexane/water and octanol/water partition coefficients, and the latter is found to be as accurate as the expensive membrane calculations, indicating a wider application area.

  18. Geoacoustic inversion of broad-band ambient noise data using undersampled and short aperture arrays

    NASA Astrophysics Data System (ADS)

    Siderius, Martin; Porter, Michael; Harrison, Chris

    2004-05-01

    Ocean ambient noise is generated in many ways such as from winds, rain and shipping. A technique has recently been developed [Harrison and Simons, J. Acoust. Soc. Am. 112 (2002)] that uses the vertical directionality of ambient noise to determine seabed properties. The ratio of beams steered towards the surface to those steered towards the bottom produces the bottom reflection loss curve. This technique was applied to data in the 200-1500-Hz band using a 16-m array. Extending this to higher frequencies allows the array length to be substantially shortened and greatly reduces interference from shipping. However, this limits the low end of the frequency spectrum since reduced aperture increases beam widths and the up/down beam ratio no longer produces reflection loss. Similarly, for high frequencies, if hydrophone spacing is greater than half-wavelength, the beamformed output is aliased and again the up/down ratio produces erroneous results. In general, frequencies much below the array design will suffer from large beams and frequencies above from undersampling. In this paper, we describe techniques for obtaining seabed properties from ambient noise measured on short or undersampled arrays. Results will be presented from the KauaiEx (July 2003) and ElbaEx (October 2003) experiments.

  19. Tectonic structure of the Tuscany-Latium Continental Shelf (Tyrrhenian Sea)

    SciTech Connect

    Bartole, R.

    1988-08-01

    An old regional seismic multicoverage reflection survey (Zone E) provides useful information on the shallow structure of the southern Tuscany-northern Latium shelf located between Elba Island and Anzio. Three main seismic units have been recognized on the grid, directly tied to the Matilde-1 offshore drilling and correlated to onshore wells and outcrops. The upper unit, characterized by continuous and generally undisturbed reflectors, is constituted by the postorogenic sedimentary cover of late Neogene-Quaternary age. This sequence unconformably lies on an intermediate unit or, when absent, a basal one. These two units, characterized by good-to-poor seismic response, are constituted by the tectonized geologic units of the Northern and Central Apennines. The intermediate unit corresponds to the Ligurids and Sicilids allochthonous complexes, while the basal unit may be attributable to the Tuscan nappe and/or the Tuscan autochthon in the shelf sector north of the Tiber River mouth, and the Umbro-Sabina units south of the same mouth. The widespread distribution and consistent thickness of the allochthonous cover (up to 1,000 msec two-way traveltime) lying over a structured substratum might be of some interest in hydrocarbon prospecting.

  20. Spatial variations in feeding habits and trophic levels of two small pelagic fish species in the central Mediterranean Sea.

    PubMed

    Rumolo, P; Bonanno, A; Barra, M; Fanelli, E; Calabrò, M; Genovese, S; Ferreri, R; Mazzola, S; Basilone, G

    2016-04-01

    Trophic ecology of adults of European sardine (Sardina pilchardus) and anchovy (Engraulis encrasicolus) was examined and compared among various regions of central Mediterranean Sea. Carbon and nitrogen stable isotope analyses (δ(13)C and δ(15)N) were adopted as a tool to determine changes in feeding behaviour of adults of sardines and anchovies. In the study period (summer) a clear geographical pattern was recognized in the isotopic composition of both species, with an increasing trend northward. The highest variations in isotopic signal were linked to the geographical positions of the samples and, especially, between pairs of areas: South Sicily/South Campania and Gulf of Gaeta/South Elba. Higher isotope values were found in the anchovies and sardines caught in northern Tyrrhenian Sea, while lower values were mostly estimated in the southern region. Higher carbon and nitrogen isotopes may reflect a more coastal behaviour of both species, being (13)C-enriched source from benthic primary producers in addition to phytoplankton. Variations in the nitrogen isotope ratio may reflect not only differences in the trophic level of prey species, but also variations in the baseline level of food webs. Our results support the hypothesis that feeding behaviour of both species is directly or indirectly influenced by local factors, or by resource partitioning based on zooplankton size. Findings can supply knowledge needed for improving fish stock management and promoting plans able to take into account also local ecosystem analysis.

  1. All-atom/coarse-grained hybrid predictions of distribution coefficients in SAMPL5

    NASA Astrophysics Data System (ADS)

    Genheden, Samuel; Essex, Jonathan W.

    2016-11-01

    We present blind predictions submitted to the SAMPL5 challenge on calculating distribution coefficients. The predictions were based on estimating the solvation free energies in water and cyclohexane of the 53 compounds in the challenge. These free energies were computed using alchemical free energy simulations based on a hybrid all-atom/coarse-grained model. The compounds were treated with the general Amber force field, whereas the solvent molecules were treated with the Elba coarse-grained model. Considering the simplicity of the solvent model and that we approximate the distribution coefficient with the partition coefficient of the neutral species, the predictions are of good accuracy. The correlation coefficient, R is 0.64, 82 % of the predictions have the correct sign and the mean absolute deviation is 1.8 log units. This is on a par with or better than the other simulation-based predictions in the challenge. We present an analysis of the deviations to experiments and compare the predictions to another submission that used all-atom solvent.

  2. Measurements and modeling of acoustic scattering from partially and completely buried spherical shells

    NASA Astrophysics Data System (ADS)

    Tesei, A.; Maguer, A.; Fox, W. L. J.; Lim, R.; Schmidt, H.

    2002-11-01

    The use of low-frequency sonars (2-15 kHz) is explored to better exploit scattering features of buried targets that can contribute to their detection and classification. Compared to conventional mine countermeasure sonars, sound penetrates better into the sediment at these frequencies, and the excitation of structural waves in the targets is enhanced. The main contributions to target echo are the specular reflection, geometric diffraction effects, and the structural response, with the latter being particularly important for man-made elastic objects possessing particular symmetries such as bodies of revolution. The resonance response derives from elastic periodic phenomena such as surface circumferential waves revolving around the target. The GOATS'98 experiment, conducted jointly by SACLANTCEN and MIT off the island of Elba, involved controlled monostatic measurements of scattering by spherical shells which were partially and completely buried in sand, and suspended in the water column. The analysis mainly addresses a study of the effect of burial on the dynamics of backscattered elastic waves, which can be clearly identified in the target responses, and is based on the comparison of measurements with appropriate scattering models. Data interpretation results are in good agreement with theory. This positive result demonstrates the applicability of low-frequency methodologies based on resonance analysis to the classification of buried objects. copyright 2002 Acoustical Society of America.

  3. Non-conformal coarse-grained potentials for water.

    PubMed

    Rodríguez-López, Tonalli; Khalak, Yuriy; Karttunen, Mikko

    2017-10-07

    Water is a notoriously difficult substance to model both accurately and efficiently. Here, we focus on descriptions with a single coarse-grained particle per molecule using the so-called approximate non-conformal and generalized Stockmayer potentials as the starting points. They are fitted using the radial distribution function and the liquid-gas density profile of the atomistic extended simple point charge (SPC/E) model by downhill simplex optimization. We compare the results with monatomic water (mW), ELBA, and direct iterative Boltzmann inversion of SPC/E. The results show that symmetrical potentials result in non-transferable models, that is, they need to be reparametrized for new state points. This indicates that transferability may require more complex models. Furthermore, the results also show that the addition of a point dipole is not sufficient to make the potentials accurate and transferable to different temperatures (300 K-500 K) and pressures without an appropriate choice of properties as targets during model optimization.

  4. Provenance of marbles used for building the internal spiral staircase of the bell tower of St. Nicholas Church (Pisa, Italy)

    NASA Astrophysics Data System (ADS)

    Lezzerini, Marco; Antonelli, Fabrizio; Gallello, Gianni; Ramacciotti, Mirco; Parodi, Luca; Alberti, Antonio; Pagnotta, Stefano; Legnaioli, Stefano; Palleschi, Vincenzo

    2017-05-01

    The aim of this study is to investigate the provenance of marbles used as architectural elements (bases, shafts and capitals of columns) for building the internal spiral staircase of the medieval bell tower of St. Nicholas Church at Pisa, Italy. Accordingly, the 45 collected marble samples have been analysed by optical microscopy, X-ray powder diffraction and mass spectroscopy for carbon and oxygen stable isotope ratio analysis; additionally, SEM-EDS analysis have been performed to complement data about accessory minerals. By comparison with literature data on the main sources of the white Mediterranean marbles used in ancient times, the results show that the analysed samples are mainly white crystalline marbles from Carrara (Italy) and, subordinately, from other Tuscan and Eastern Mediterranean quarrying areas. In fact, Mt. Pisano and Campiglia M.ma (Tuscany, Italy) and Marmara (Turkey), Paros, Mt. Penteli, Thasos (Greece) are minor sources. The other coloured stones identified on the strength of their macroscopic features are quartzites from Mt. Pisano area and granitoids from Sardinia and Island of Elba (Italy). Occasionally, a very limited number of architectonical elements made up of Acquabona limestone from Rosignano Marittimo (Livorno, Italy), red limestone with ammonites (the so-called "Rosso Ammonitico") and black limestone belonging to the Tuscan Nappe sequence, outcropping at northwest of Pisa in the nearby Monti d'Oltre Serchio area, are present.

  5. Effect of solvent model when probing protein dynamics with molecular dynamics.

    PubMed

    Genheden, Samuel

    2017-01-01

    We probe the dynamics of the Bpti and Galectin-3 proteins using molecular dynamics simulations employing three water models at different levels of resolution, viz. the atomistic TIP4P-Ewald, the coarse-grained Elba and an implicit generalised Born model. The dynamics are quantified indirectly by model-free order parameters, S(2) of the backbone NH and selected side-chain bond vectors, which also have been determined experimentally through NMR relaxation measurements. For the backbone, the order parameters produced with the three solvent models agree to a large extent with experiments, giving average unsigned deviations between 0.03 and 0.06. For the side-chains, for which the experimental data is incomplete, the deviations are considerably larger with mean deviations between 0.13 and 0.17. However, for both backbone and side-chains, it is difficult to pick a winner, as all models perform equally well overall. For a more complete set of side-chain vectors, we resort to analysing the variation among the estimates from different solvent models. Unfortunately, the variations are found to be sizeable with mean deviations between 0.11 and 0.15. Implications for computational assessment of protein dynamics are discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Microbial diversity in Calamita ferromagnetic sand.

    PubMed

    Perfumo, Amedea; Cockell, Charles; Elsaesser, Andreas; Marchant, Roger; Kminek, Gerhard

    2011-08-01

    Calamita is a black ferromagnetic sand from a marine iron ore on Elba Island (Italy). Its total iron content is approximately 80% and a major fraction (63% w/w) has magnetic properties. Desiccation, ultraviolet irradiation and the high temperature induced by the thermal conductivity of iron make Calamita sand an extreme biotope. We report, for the first time, the geomicrobiological characterization of Calamita sand, which showed a low bacterial biodiversity as determined by denaturing gradient gel electrophoresis and 16S rRNA gene clone library analysis. We retrieved sequences closely affiliated with uncultured bacteria inhabiting the harshest deserts on Earth. Radiation- and desiccation-tolerant bacteria from the phyla Proteobacteria, Actinobacteria and Deinococcus-Thermus dominated the community. Heavy metal-resistant organisms, for example Variovorax sp. were also abundant. Sequences of organisms with an inferred metabolism based on lithotrophic iron oxidation were detected. The sands also contained thermophilic bacilli, which were cultivated at 60°C. These data provided important insights also into the biogeographical distribution of these organisms in the Mediterranean region. In summary, this study on Calamita helps to expand our knowledge of the biodiversity in extreme, iron-rich, environments. © 2011 Society for Applied Microbiology and Blackwell Publishing Ltd.

  7. Clones identification and genetic characterization of Garnacha grapevine by means of different PCR-derived marker systems.

    PubMed

    Meneghetti, Stefano; Costacurta, Angelo; Frare, Enrica; Da Rold, Graziana; Migliaro, Daniele; Morreale, Giacomo; Crespan, Manna; Sotés, Vicente; Calò, Antonio

    2011-07-01

    This study uses PCR-derived marker systems to investigate the extent and distribution of genetic variability of 53 Garnacha accessions coming from Italy, France and Spain. The samples studied include 28 Italian accessions (named Tocai rosso in Vicenza area; Alicante in Sicily and Elba island; Gamay perugino in Perugia province; Cannonau in Sardinia), 19 Spanish accessions of different types (named Garnacha tinta, Garnacha blanca, Garnacha peluda, Garnacha roja, Garnacha erguida, Garnacha roya) and 6 French accessions (named Grenache and Grenache noir). In order to verify the varietal identity of the samples, analyses based on 14 simple sequence repeat (SSR) loci were performed. The presence of an additional allele at ISV3 locus (151 bp) was found in four Tocai rosso accessions and in a Sardinian Cannonau clone, that are, incidentally, chimeras. In addition to microsatellite analysis, intravarietal variability study was performed using AFLP, SAMPL and M-AFLP molecular markers. AFLPs could discriminate among several Garnacha samples; SAMPLs allowed distinguishing few genotypes on the basis of their geographic origin, whereas M-AFLPs revealed plant-specific markers, differentiating all accessions. Italian samples showed the greatest variability among themselves, especially on the basis of their different provenance, while Spanish samples were the most similar, in spite of their morphological diversity.

  8. Variations of vessel diameter and δ13C in false rings of Arbutus unedo L. reflect different environmental conditions.

    PubMed

    Battipaglia, Giovanna; De Micco, Veronica; Brand, Willi A; Linke, Petra; Aronne, Giovanna; Saurer, Matthias; Cherubini, Paolo

    2010-12-01

    Woody species in Mediterranean ecosystems form intra-annual density fluctuations (IADFs) in tree rings in response to changes in environmental conditions, especially water availability. Dendrochronology, quantitative wood anatomy and high-resolution isotopic analysis (using a laser ablation technique) were used to characterize IADFs in Arbutus unedo shrubs grown on two sites with different water availability on the island of Elba (Italy). Our findings show that IADF characterization can provide information about the relationship between environmental factors and tree growth at the seasonal level. At the more xeric site, IADFs mainly located in the early and middle parts of the annual ring, showed a decrease in vessel size and an increase in δ(13) C as a result of drought deficit. Opposite trends were found at the more mesic site, with IADFs located at the end of the ring and associated with a lower δ(13) C. Moreover, at the first site, IADFs are induced by drought deficit, while at the second site IADFs are linked with the regrowth in the last part of the growing season triggered by favourable wet conditions. This combined approach is a promising way for dating problematic wood samples and interpreting the phenomena that trigger the formation of IADFs in the Mediterranean environment. © The Authors (2010). Journal compilation © New Phytologist Trust (2010).

  9. Underwater Acoustic Source Localisation Among Blind and Sighted Scuba Divers

    PubMed Central

    Cambi, Jacopo; Livi, Ludovica; Livi, Walter

    2017-01-01

    Objectives Many blind individuals demonstrate enhanced auditory spatial discrimination or localisation of sound sources in comparison to sighted subjects. However, this hypothesis has not yet been confirmed with regards to underwater spatial localisation. This study therefore aimed to investigate underwater acoustic source localisation among blind and sighted scuba divers. Methods This study took place between February and June 2015 in Elba, Italy, and involved two experimental groups of divers with either acquired (n = 20) or congenital (n = 10) blindness and a control group of 30 sighted divers. Each subject took part in five attempts at an under-water acoustic source localisation task, in which the divers were requested to swim to the source of a sound originating from one of 24 potential locations. The control group had their sight obscured during the task. Results The congenitally blind divers demonstrated significantly better underwater sound localisation compared to the control group or those with acquired blindness (P = 0.0007). In addition, there was a significant correlation between years of blindness and underwater sound localisation (P <0.0001). Conclusion Congenital blindness was found to positively affect the ability of a diver to recognise the source of a sound in an underwater environment. As the correct localisation of sounds underwater may help individuals to avoid imminent danger, divers should perform sound localisation tests during training sessions. PMID:28690888

  10. ELITE S2 - A Facility for Quantitative Human Movement Analysis on Board the ISS

    NASA Astrophysics Data System (ADS)

    Neri, Gianluca; Mascetti, Gabriele; Zolesi, Valfredo

    2014-11-01

    This paper describes the activities for utilization and control of ELITE S2 on board the International Space Station (ISS). ELITE S2 is a payload of the Italian Space Agency (ASI) for quantitative human movement analysis in weightlessness. Within the frame of a bilateral agreement with NASA, ASI has funded a number of facilities, enabling different scientific experiments on board the ISS. ELITE S2 has been developed by the ASI contractor Kayser Italia, delivered to the Kennedy Space Center in 2006 for pre-flight processing, launched in 2007 by the Space Shuttle Endeavour (STS-118), integrated in the U.S. lab and used during the Increments 16/17 (2008) and 33/34 (2012/2013). The ELITE S2 flight segment comprises equipment mounted into an Express Rack and a number of stowed items to be deployed for experiment performance (video cameras and accessories). The ground segment consists in a User Support Operations Center (based at Kayser Italia) enabling real-time payload control and a number of User Home Bases (located at the ASI and PIs premises), for the scientific assessment of the experiment performance. Two scientific protocols on reaching and cognitive processing have been successfully performed in eight sessions involving three ISS crewmembers: IMAGINE 2 and MOVE.

  11. Sperm whale assessment in the Western Ionian Sea using acoustic data from deep sea observatories

    NASA Astrophysics Data System (ADS)

    Caruso, Francesco; Bellia, Giorgio; Beranzoli, Laura; De Domenico, Emilio; Larosa, Giuseppina; Marinaro, Giuditta; Papale, Elena; Pavan, Gianni; Pellegrino, Carmelo; Pulvirenti, Sara; Riccobene, Giorgio; Scandura, Danila; Sciacca, Virginia; Viola, Salvatore

    2015-04-01

    The Italian National Institute of Nuclear Physics (INFN) operates two deep sea infrastructures: Capo Passero, Western Ionian Sea 3,600 meters of depth, and Catania Wester Ionian Sea 2,100 m depth. At the two sites, several research observatories have been run: OnDE, NEMO-SN1, SMO, KM3NeT-Italia most of them jointly operated between INFN and INGV. In all these observatories, passive acoustic sensors (hydrophones) have been installed. Passive Acoustics Monitoring (PAM) is nowadays the main tool of the bioacoustics to study marine mammals. In particular, receiving the sounds emitted by cetaceans from a multi-hydrophones array installed in a cabled seafloor observatory, a research about the ecological dynamics of the species may be performed. Data acquired with the hydrophones installed aboard the OnDE, SMO and KM3NeT-Italia observatories will be reported. Thanks to acquired data, the acoustic presence of the sperm whales was assessed and studied for several years (2005:2013). An "ad hoc" algorithm was also developed to allow the automatic identification of the "clicks" emitted by the sperm whales and measure the size of detected animals. According to the results obtained, the sperm whale population in the area is well-distributed in size, sex and sexual maturity. Although specimens more than 14 meters of length (old males) seem to be absent.

  12. EXOMARS Descent Module GNC Performance

    NASA Astrophysics Data System (ADS)

    Portigliotti, S.; Capuano, M.; Montagna, M.; Martella, P.; Venditto, P.

    2007-08-01

    The ExoMars mission is the first ESA led robotic mission of the Aurora Programme and combines technology development with investigations of major scientific interest. Italy is by far the major contributor to the mission through the strong support of the Italian Space Agency (ASI). ExoMars will search for traces of past and present life, characterize the Mars geochemistry and water distribution, improve the knowledge of the Mars environment and geophysics, and identify possible surface hazards to future human exploration missions. ExoMars will also validate the technology for safe Entry, Descent and Landing (EDL) of a large size Descent Module (DM) carrying a Rover with medium range surface mobility and the access to subsurface. The ExoMars project is presently undergoing its Phase B1 with Thales Alenia Space-Italia as Industrial Prime Contractor. Additionally, as Descent Module responsible, a dedicated simulation tool is under development in Thales Alenia Space-Italia, Turin site, for the end-to-end design and validation / verification of the DM Entry Descent and Landing.

  13. [Health expenditure for prevention in Italy (2006-2013): descriptive analysis, regional trends and international comparisons].

    PubMed

    Signorelli, Carlo; Odone, Anna; Bianco, Daniela; Di Vivo, Natalia; Bevere, Francesco

    2016-01-01

    Il dato dell'Organizzazione per la cooperazione e lo sviluppo economico (OCSE) del 2012, che indicava l'Italia come il Paese con la più bassa spesa in prevenzione sanitaria, ha dato lo spunto per una raccolta sistematica e un'analisi critica dei flussi disponibili sulla spesa per le attività di prevenzione in Italia. Le statistiche correnti di spesa sanitaria sono raccolte centralmente dall'Agenzia nazionale per i servizi sanitari regionali (Agenas) attraverso i modelli di rilevazione dei costi dei livelli essenziali di assistenza (LEA) delle aziende USL. Le tre macroaree dei LEA sono: assistenza distrettuale, assistenza ospedaliera e assistenza sanitaria collettiva in ambiente di vita e di lavoro. Le spese per la prevenzione rientrano in quest'ultima e sono ripartite nelle seguenti voci: attività di prevenzione rivolte alle persone, igiene degli alimenti e della nutrizione, igiene e sanità pubblica, prevenzione e sicurezza negli ambienti di lavoro, sanità pubblica veterinaria, attività medico-legale per finalità pubblica. Tra il 2006 e il 2013, ultimo dato disponibile, la spesa per le attività di prevenzione del Servizio sanitario nazionale (SSN) è rimasta costante in rapporto alla spesa sanitaria totale (4,2%), pari a 4,9 miliardi nel 2013. Nel periodo di studio considerato (2006-2013) appaiono in aumento le spese per le attività rivolte alle persone (+8,7%), attribuibili soprattutto a vaccinazioni e screening, e in diminuzione le attività di igiene pubblica (-5,7%) e quelle della sanità pubblica veterinaria (-3,8%). I confronti internazionali indicano una spesa per la prevenzione del 2,9% rispetto alla spesa sanitaria totale, costante negli anni e nella media dei Paesi OCSE. Per la prevenzione, l'Italia spende tanto quanto i Paesi che non possiedono un servizio sanitario pubblico; il dato risulta inferiore del 5% rispetto alla programmazione nazionale, con poche eccezioni e molta variabilità regionale all'interno delle componenti delle voci di spesa

  14. Insights From in-situ U-Pb, Trace Elements and Hf Isotopic Analyses in Zircon From a Young, Incrementally-Filled, Monzogranitic Pluton

    NASA Astrophysics Data System (ADS)

    Gagnevin, D.; Daly, J. S.; Horstwood, M.; Whitehouse, M. J.; Kirkland, C. L.

    2007-12-01

    Ion microprobe U-Pb zircon analyses of the Miocene Monte Capanne pluton (Tuscan Magmatic Province, Elba, Italy) - one of the youngest granitic plutons exposed on Earth - reveal ages consistent with incremental intrusion of the three petrographically defined facies of the pluton (Dini et al. 2002). A positive correlation between U-Pb age and high uranium contents (up to 3%) compromises the apparently large age range (7-10 Ma) for the duration of magmatism and is attributed to an unconstrained matrix effect during sputtering. Selecting only zircon data with normal U concentrations, suggests timescales in the order of ca. 1 Ma (from 8.08 ± 0.09 Ma to 7.04 ± 0.29 Ma), i.e., of similar range to magmatic activity in the coeval Capraia volcano (from 7.80 ± 0.08 Ma to 7.10 ± 0.09 Ma), North of Elba. Importantly, zircon ages for the components of the pluton (mafic enclaves, dykes, granite porphyries) partially overlap, suggesting that zircon was transferred and/or recycled throughout the lifetime of the whole plutonic system. Much older inherited zircons also occur (from Archaean to Mesozoic) and are interpreted as being derived mostly from the wall rocks. Detailed BSE imaging has revealed a variety of textures (including patchy-zoning, small and large scale oscillatory zoning etc), associated with an extremely large range of trace to minor elements compositions (e.g., (P, Th, U, Y and HREE) are interpreted to reflect changes in melt chemistry due to iterative mixing and recharge, where growth/resorption of zircon was also associated with reactions between other accessory minerals (particularly monazite, allanite and apatite; Dini et al., 2004). ɛHf(t) ranges from -14.95 to -4.25 and two populations are found in almost every component of the pluton, which concur with the magma mixing model. A positive correlation between Th and ɛHf(t) may be related to some wall-rock contamination (in agreement with the occurrence of xenocrystic zircon in most of magma products) and

  15. K-feldspar megacrysts growth and their link to the granitic mush: insight from high precision U-Pb dates (ID-TIMS) and trace elements (TIMS-TEA) on zircon

    NASA Astrophysics Data System (ADS)

    Barboni, M.; Schoene, B.

    2012-12-01

    K-feldspar megacrysts are common in granitic to granodioritic rocks though their origin and evolution is still poorly understood. Their occurrence seems to reflect a low nucleation rate relative to growth rate at low degrees of supersaturation. Though K-feldspar has been argued to be one of the last minerals to saturate in felsic magma, crystal mush may still contain 60-70% liquid at the initiation of crystallization. Therefore, abundant liquid might be available for development of large crystals early in the magma cooling process. The recent recognition that many granitoid plutons are built incrementally by many magma injections open new perspectives for K-feldspar megacrysts formation. Repeated replenishment, reheating and reinvigoration of the mush might play a significant role in making and preserving K-feldspar megacrysts. The Miocene Elba island intrusives (Italy) are famous for having some of the largest K-feldspar megacrysts ever found (up to 25 cm.). This young plutonic body emplaced incrementally at shallow crustal level (ca. 3km) and displays extensive evidence of interactions between magmas of contrasting compositions. We have sampled three different families of K-feldspar megacrysts occurring in different host rock and have combined U/Pb high precision dates (ID-TIMS) with trace elements (TIMS-TEA) and Hf isotopes of zircons that are included within the K-feldspar megacrysts and compared them to zircons from the host rock. Ages of zircon included in the megacrysts could document whether the crystals grew early in the magmatic system (inclusions older than the host rock) or late during the cooling history (similar ages within inclusions and host rock). Ti-in zircon thermometer combined with trace-elements signature could record slight differences between megacrysts and host rock zircons, documenting the development of the megacrysts in comparison with the one of the host granite. Strong field evidence support a magmatic/ phenocrystic origin for the Elba

  16. Earth Observations taken by the Expedition 13 crew

    NASA Image and Video Library

    2006-09-06

    ISS013-E-78295 (6 Sept. 2006) --- Haze in the Po River Valley of Italy is featured in this image photographed by an Expedition 13 crewmember onboard the International Space Station. The valley is visible across the horizontal center of the frame, with the floor obscured by what NASA scientists refer to as frequent atmospheric haze, a mixture of industrial pollutants, dust and smoke. The visual texture of such haze is perceptibly different from that of bright white clouds which stretch across the top of the scene and cover part of the Alps. The Po River Valley is Italy's industrial heartland and one of the most industrialized regions on Earth, according to scientists. Northern Italy is in the foreground of this southwesterly view. The partially cloud-covered Alps are at lower right; the Adriatic Sea at lower left. Corsica is under partial cloud cover at center; and Sardinia, almost totally obscured, is to its south. The island of Elba is visible just to the west of Italy. By contrast with haze accumulation along the axis of the valley, the Alps and the Apennines are clearly visible, and Lake Garda can be seen in the foothills of the Alps. Other visible geographic features are the lagoon at Venice north of the Po River delta, and three small lakes north of Rome. The winds on the day this image was taken are mainly from the north, as shown by the flow lines in the haze near Venice. The haze typically flows south down the Adriatic Sea. Visibility in the Mediterranean basin is often reduced by hazes such as these, deriving from different sources in industrialized Europe.

  17. Soil and plant changing after invasion: the case of Acacia dealbata in a Mediterranean ecosystem.

    PubMed

    Lazzaro, Lorenzo; Giuliani, Claudia; Fabiani, Arturo; Agnelli, Alessandro Elio; Pastorelli, Roberta; Lagomarsino, Alessandra; Benesperi, Renato; Calamassi, Roberto; Foggi, Bruno

    2014-11-01

    Acacia dealbata Link (Fabaceae) is one of the most invasive species in the Mediterranean ecosystems of Europe, Africa and America, where it has been proved to exert strong effects on soil and plant communities. In Italy A. dealbata has been largely used for ornamental and forestry purpose and is nowadays spreading in several areas. The present study was addressed to evaluate the impacts on soil chemical properties, soil microbial communities and understory plant communities and to assess the relationships among these compartments after the invasion of A. dealbata in a typical Mediterranean shrubland. Towards these aims, a soil and vegetation sampling was performed in Elba Island where A. dealbata is invading the sclerophyllous native vegetation. Three levels of invasion status were differentiated according to the gradient from invaded, to transitional and non-invaded vegetation. Quantitative and qualitative alterations of soil chemical properties and microbial communities (i.e. bacterial and fungal communities) and above-ground understory plant communities were found. In particular, the invaded soils had lower pH values than both the non-invaded and transitional ones. High differences were detected for both the total N and the inorganic fraction (NH4(+) and NO3(-)) contents, which showed the ranking: invaded>transitional>non-invaded soils. TOC and C/N ratio showed respectively higher and lower values in invaded than in non-invaded soils. Total plant covers, species richness and diversity in both the non-invaded and transitional subplots were higher than those in the invaded ones. The contribution of the nitrophilous species was significantly different among the three invasion statuses, with a strong increase going from native to transitional and invaded subplots. All these data confirm that A. dealbata modifies several compartments of the invaded ecosystems, from soil chemical properties to soil and plant microbial communities determining strong changes in the

  18. Experimental demonstration of the utility of pressure sensitivity kernels in time-reversal.

    PubMed

    Raghukumar, Kaustubha; Cornuelle, Bruce D; Hodgkiss, William S; Kuperman, William A

    2010-09-01

    Pressure sensitivity kernels were recently applied to time-reversal acoustics in an attempt to explain the enhanced stability of the time-reversal focal spot [Raghukumar et al., J. Acoust. Soc. Am. 124, 98-112 (2008)]. The theoretical framework developed was also used to derive optimized source functions, closely related to the inverse filter. The use of these optimized source functions results in an inverse filter-like focal spot which is more robust to medium sound speed fluctuations than both time-reversal and the inverse filter. In this paper the theory is applied to experimental data gathered during the Focused Acoustic Fields experiment, conducted in 2005, north of Elba Island in Italy. Sensitivity kernels are calculated using a range-independent sound-speed profile, for a geometry identical to that used in the experiment, and path sensitivities are identified with observed arrivals. The validity of the kernels in tracking time-evolving Green's functions is studied, along with limitations that result from a linearized analysis. An internal wave model is used to generate an ensemble of sound speed profiles, which are then used along with the calculated sensitivity kernels to derive optimized source functions. Focal spots obtained using the observed Green's functions with these optimized source functions are then compared to those obtained using time-reversal and the inverse-filter. It is shown that these functions are able to provide a focal spot superior to time-reversal while being more robust to sound speed fluctuations than the inverse filter or time-reversal.

  19. Crustal shortening and duplication of the Moho in the Northern Apennines: a view from seismic refraction data

    NASA Astrophysics Data System (ADS)

    Ponziani, F.; De Franco, R.; Minelli, G.; Biella, G.; Federico, C.; Pialli, G.

    1995-12-01

    A reappraisal of the DSS refraction seismic campaigns of 1978 and 1974 in the Northern Apennines and the northern Tyrrhenian Sea, after digitization of the original analog data, and a new interpretation of crustal structures are presented in this paper. The layering of the Adria crust consists of a low-velocity lower crust topped by a 6.7 km/s horizon and an upper crust again formed by a low-velocity layer capped by a faster one. In the Tuscany sector the crust-mantle boundary and lower crust show attenuated velocities and a reduced thickness with respect to the Adriatic counterpart. These differences are due to the extensional tectonics, restricted to Tuscany and occurred in a high heat flow regime related to an uplifting astenosphere. It has been confirmed that a deep thrust is responsible for Moho doubling in correspondence with the zero-Bouguer anomaly line: the Tuscan Moho overlaps the Umbro-Marchean one for a length of about 30 km. It is hypothesized that another shallower thrust involves upper crust in the Mid-Tuscany Range, Mt. Cetona and Perugia Massifs had their roots in the mantle and that subsequent extensional tectonics obliterated every trace of thrusting in lower crust and mantle rocks. No conclusive proof of the existence of a European Moho below a Tuscan one in the area underneath Elba has yet been found. Revision of DSS data excludes the presence of a refractor-reflector 60 km deep; the same data, however, are compatible with the existence of a crust-mantle boundary at 30-35 km depth.

  20. Uranium potential of precambrian rocks in the Raft River area of northwestern Utah and south-central Idaho. Final report

    SciTech Connect

    Black, B.A.

    1980-09-01

    A total of 1214 geochemical samples were collected and analyzed. The sampling media included 334 waters, 616 stream sediments, and 264 rocks. In addition, some stratigraphic sections of Elba and Yost Quartzites and Archean metasedimentary rock were measured and sampled and numerous radiation determinations made of the various target units. Statistical evaluation of the geochemical data permitted recognition of 156 uranium anomalies, 52 in water, 79 in stream sediment, and 25 in rock. Geographically, 68 are located in the Grouse Creek Mountains, 43 in the Raft River Mountains, and 41 in the Albion Range. Interpretation of the various data leads to the conclusion that uranium anomalies relate to sparingly and moderately soluble uraniferous heavy minerals, which occur as sparse but widely distributed magmatic, detrital, and/or metamorphically segregated components in the target lithostratigraphic units. The uraniferous minerals known to occur and believed to account for the geochemical anomalies include allanite, monazite, zircon, and apatite. In some instances samarskite may be important. These heavy minerals contain uranium and geochemically related elements, such as Th, Ce, Y, and Zr, in sufficient quantities to account for both the conspicuous lithologic preference and the generally observed low amplitude of the anomalies. The various data generated in connection with this study, as well as those available in the published literature, collectively support the conclusion that the various Precambrian W and X lithostratigraphic units pre-selected for evaluation probably lack potential to host important Precambrian quartz-pebble conglomerate uranium deposits. Moreover it is also doubted that they possess any potential to host Proterozoic unconformity-type uranium deposits.

  1. Rare-element granitic pegmatite of Miocene age emplaced in UHP rocks from Visole, Pohorje Mountains (Eastern Alps, Slovenia): accessory minerals, monazite and uraninite chemical dating

    NASA Astrophysics Data System (ADS)

    Uher, Pavel; Janák, Marian; Konečný, Patrik; Vrabec, Mirijam

    2014-04-01

    The granitic pegmatite dike intruded the Cretaceous UHP rocks at Visole, near Slovenska Bistrica, in the Pohorje Mountains (Slovenia). The rock consists mainly of K-feldspar, albite and quartz, subordinate muscovite and biotite, while the accessory minerals include spessartine-almandine, zircon, ferrocolumbite, fluorapatite, monazite- (Ce), uraninite, and magnetite. Compositions of garnet (Sps48-49Alm45-46Grs + And3-4 Prp1.5-2), metamict zircon with 3.5 to 7.8 wt. % HfO2 [atom. 100Hf/(Hf + Zr) = 3.3-7.7] and ferrocolumbite [atom. Mn/(Mn + Fe) = 0.27-0.43, Ta/(Ta + Nb) = 0.03-0.46] indicate a relatively low to medium degree of magmatic fractionation, characteristic of the muscovite - rare-element class or beryl-columbite subtype of the rare-element class pegmatites. Monazite-(Ce) reveals elevated Th and U contents (≤11 wt. % ThO2, ≤5 wt. % UO2). The monazite-garnet geothermometer shows a possible precipitation temperature of ~495 ± 30 °C at P~4 to 5 kbar. Chemical U-Th-Pb dating of the monazite yielded a Miocene age (17.2 ± 1.8 Ma), whereas uraninite gave a younger (~14 Ma) age. These ages are comtemporaneous with the main crystallization and emplacement of the Pohorje pluton and adjacent volcanic rocks (20 to 15 Ma), providing the first documented evidence of Neogene granitic pegmatites in the Eastern Alps. Consequently, the Visole pegmatite belongs to the youngest rare-element granitic pegmatite populations in Europe, together with the Paleogene pegmatite occurrences along the Periadriatic (Insubric) Fault System in the Alps and in the Rhodope Massif, as well as the Late Miocene to Pliocene pegmatites in the Tuscany magmatic province (mainly on the Island of Elba).

  2. Italian Dermestidae: notes on some species and an updated checklist (Coleoptera)

    PubMed Central

    Nardi, Gianluca; Háva, Jiří

    2013-01-01

    Abstract An up-to-date checklist of the Italian Dermestidae is provided. The presence of 95 species in Italy is confirmed, while further 5 species (Dermestes (Dermestes) vorax Motschulsky, 1860, Thorictuspilosus Peyron, 1857, T. wasmanni Reitter, 1895, Attagenus (Attagenus) simonis Reitter, 1881 and Globicornis (G.) breviclavis (Reitter, 1878)) and 1 subspecies (A. (A.) tigrinus pulcher Faldermann, 1835) are excluded from the Italian fauna. Attagenus (Attagenus) calabricus Reitter, 1881 and A. (A.) lobatus Rosenhauer, 1856 are for the first time recorded from Abruzzi and Tuscany respectively; A. (A.) silvaticus Zhantiev, 1976 is recorded for the first time from mainland Italy (Apulia); Anthrenus (Anthrenus) angustefasciatus Ganglbauer, 1904 is new to northern Italy (Friuli-Venezia Giulia), central Italy (Tuscany), Apulia and Basilicata; A. (A.) munroi Hinton, 1943 is new to central Italy (Elba Island); A. (A.) delicatus Kiesenwetter, 1851 is for the first time recorded from Apulia; Globicornis (Globicornis) fasciata (Fairmaire & Brisout de Barneville, 1859) is new to southern Italy (Basilicata); G. (Hadrotoma) sulcata (C.N.F. Brisout de Barneville, 1866) is for the first time recorded from central Italy (Abruzzi), Campania and Sicily, whileTrogoderma inclusum LeConte, 1854 is new to Apulia. Seven species (Dermestes (Dermestes) peruvianus Laporte de Castelnau, 1840, D. (Dermestinus) carnivorus Fabricius, 1775, D. (Dermestinus) hankae Háva, 1999, D. (Dermestinus) intermedius intermedius Kalík, 1951, D. (Dermestinus) szekessyi Kalík, 1950, Anthrenus (Anthrenops) coloratus Reitter, 1881 and Trogodermaangustum (Solier, 1849)) recently recorded from Italy (without further details) are discussed. The lectotype and a paralectotype are designated forAttagenus (A.) calabricus Reitter, 1881 from Calabria. Attagenus pellio (Linnaeus, 1758) var. pilosissimus Roubal, 1932 is removed from synonymy with A. (A.) pellio and recognized as a valid species (stat. prom.); it is known

  3. Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects : Insect insulator proteins.

    PubMed

    Pauli, Thomas; Vedder, Lucia; Dowling, Daniel; Petersen, Malte; Meusemann, Karen; Donath, Alexander; Peters, Ralph S; Podsiadlowski, Lars; Mayer, Christoph; Liu, Shanlin; Zhou, Xin; Heger, Peter; Wiehe, Thomas; Hering, Lars; Mayer, Georg; Misof, Bernhard; Niehuis, Oliver

    2016-11-03

    Body plan development in multi-cellular organisms is largely determined by homeotic genes. Expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (IBPs). While only a few enhancer blocking IBPs have been identified in vertebrates, the common fruit fly Drosophila melanogaster harbors at least twelve different enhancer blocking IBPs. We screened recently compiled insect transcriptomes from the 1KITE project and genomic and transcriptomic data from public databases, aiming to trace the origin of IBPs in insects and other arthropods. Our study shows that the last common ancestor of insects (Hexapoda) already possessed a substantial number of IBPs. Specifically, of the known twelve insect IBPs, at least three (i.e., CP190, Su(Hw), and CTCF) already existed prior to the evolution of insects. Furthermore we found GAF orthologs in early branching insect orders, including Zygentoma (silverfish and firebrats) and Diplura (two-pronged bristletails). Mod(mdg4) is most likely a derived feature of Neoptera, while Pita is likely an evolutionary novelty of holometabolous insects. Zw5 appears to be restricted to schizophoran flies, whereas BEAF-32, ZIPIC and the Elba complex, are probably unique to the genus Drosophila. Selection models indicate that insect IBPs evolved under neutral or purifying selection. Our results suggest that a substantial number of IBPs either pre-date the evolution of insects or evolved early during insect evolution. This suggests an evolutionary history of insulator binding proteins in insects different to that previously thought. Moreover, our study demonstrates the versatility of the 1KITE transcriptomic data for comparative analyses in insects and other arthropods.

  4. Basement provenance revealed by U-Pb detrital zircon ages: A tale of African and European heritage in Tuscany, Italy

    NASA Astrophysics Data System (ADS)

    Paoli, Gabriele; Stokke, Henrik H.; Rocchi, Sergio; Sirevaag, Hallgeir; Ksienzyk, Anna K.; Jacobs, Joachim; Košler, Jan

    2017-04-01

    A new data set of ca. 500 LA-ICP-MS U-Pb detrital zircon ages for six metasedimentary units from the Tuscan basement (Apuan Alps, Monti Pisani, Monticiano-Roccastrada), along with a precise SHRIMP U-Pb crystallization age of a metavolcanic unit (Apuan Alps) have been collected to determine their depositional ages and provenance. These results have been integrated with the recently published ca. 900 U-Pb detrital zircon ages from Elba Island to draw a complete picture of the Paleozoic journey of the Tuscan basement. A major change in the sources supplying sediments to the Tuscan basins is shown to occur during this journey. Detrital zircon ages of early Cambrian to middle Ordovician metasediments mirror those of coeval northern Africa sediments: most samples were sourced in western Africa, while one sample is derived material from central northern Africa. The Tuscan block was therefore located at the peri-Gondwana margin, close to central northern Africa. The prominent mid-Ordovician magmatic arc activity (ca. 460 Ma) at the northern Gondwana margin and its detritus, characterise the zircon age distribution of Ordovician and Silurian volcano-sedimentary rocks, that were therefore generated at the northernmost Gondwana margin during subduction and subsequent initial Paleotethys rifting. The Carboniferous-Permian metasediments are dominated by populations of Ordovician and Variscan-age zircons, with a minor occurrence of Neoarchean and Paleoproterozoic zircons that is best explained by recycling of European Neoproterozoic-Cambrian metasediments. In summary, the main sources supplying the Tuscan basins were located in northern Africa throughout Cambrian-Ordovician times, shifting to the volcanic arc active at the northern Gondwana margin during the middle Ordovician. During Variscan and post-Variscan times, detrital zircon sources were mostly located in European terrains, witnessing the shift of Tuscany from Africa to Europe.

  5. Forecast of drifter trajectories using a Rapid Environmental Assessment based on CTD observations

    NASA Astrophysics Data System (ADS)

    Sorgente, R.; Tedesco, C.; Pessini, F.; De Dominicis, M.; Gerin, R.; Olita, A.; Fazioli, L.; Di Maio, A.; Ribotti, A.

    2016-11-01

    A high resolution submesoscale resolving ocean model was implemented in a limited area north of Island of Elba where a maritime exercise, named Serious Game 1 (SG1), took place on May 2014 in the framework of the project MEDESS-4MS (Mediterranean Decision Support System for Marine Safety). During the exercise, CTD data have been collected responding to the necessity of a Rapid Environmental Assessment, i.e. to a rapid evaluation of the marine conditions able to provide sensible information for initialisation of modelling tools, in the scenario of possible maritime accidents. The aim of this paper is to evaluate the impact of such mesoscale-resolving CTD observations on short-term forecasts of the surface currents, within the framework of possible oil-spill related emergencies. For this reason, modelling outputs were compared with Lagrangian observations at sea: the high resolution modelled currents, together with the ones of the coarser sub-regional model WMED, are used to force the MEDSLIK-II oil-spill model to simulate drifter trajectories. Both ocean models have been assessed by comparing the prognostic scalar and vector fields as an independent CTD data set and with real drifter trajectories acquired during SG1. The diagnosed and prognosed circulation reveals that the area was characterised by water masses of Atlantic origin influenced by small mesoscale cyclonic and anti-cyclonic eddies, which govern the spatial and temporal evolution of the drifter trajectories and of the water masses distribution. The assimilation of CTD data into the initial conditions of the high resolution model highly improves the accuracy of the short-term forecast in terms of location and structure of the thermocline and positively influence the ability of the model in reproducing the observed paths of the surface drifters.

  6. Sentinel-1 Instrument Overview

    NASA Astrophysics Data System (ADS)

    Snoeij, Paul; Torres, Ramon; Geudtner, Dirk; Brown, Michael; Deghaye, Patrick; Navas-Traver, Ignacio; Ostergaard, Allan; Rommen, Bjorn; Floury, Nicolas; Davidson, Malcolm

    2013-03-01

    The forthcoming European Space Agency (ESA) Sentinel-1 (S-1) C-band SAR constellation will provide continuous all-weather day/night global coverage, with six days exact repetition time (near daily coverage over Europe and Canada) and with radar data delivery within 3 to 24 hours. These features open new possibilities for operational maritime services. The Sentinel-1 space segment has been designed and is being built by an industrial consortium with Thales Alenia Space Italia as prime contractor and EADS Astrium GmbH as C-SAR instrument responsible. It is expected that Sentinel-1A be launched in 2013. This paper will provide an overview of the Sentinel-1 system, the status and characteristics of the technical implementation. The key elements of the system supporting the maritime user community will be highlighted.

  7. Copernicus Sentinel-1 Satellite And C-SAR Instrument

    NASA Astrophysics Data System (ADS)

    Panetti, Aniceto; Rostan, Friedhelm; L'Abbate, Michelangelo; Bruno, Claudio; Bauleo, Antonio; Catalano, Toni; Cotogni, Marco; Galvagni, Luigi; Pietropaolo, Andrea; Taini, Giacomo; Venditti, Paolo; Huchler, Markus; Torres, Ramon; Lokaas, Svein; Bibby, David

    2013-12-01

    The Copernicus Sentinel-1 Earth Radar Observatory, a mission funded by the European Union and developed by ESA, is a constellation of two C-band radar satellites. The satellites have been conceived to be a continuous and reliable source of C-band SAR imagery for operational applications such as mapping of global landmasses, coastal zones and monitoring of shipping routes. The Sentinel-1 satellites are built by an industrial consortium led by Thales Alenia Space Italia as Prime Contractor and with Astrium GmbH as SAR Instrument Contractor. The paper describes the general satellite architecture, the spacecraft subsystems, AIT flow and the satellite key performances. It provides also an overview on the C-SAR Instrument, its development status and pre- launch SAR performance prediction.

  8. The STEPS Approach for the Design and the Verification of Vision Based Planetary Precision Landing

    NASA Astrophysics Data System (ADS)

    Paccagnini, Carlo; Cometto, Ferdinando; Lanza, Piergiorgio; Maddaleno, Corrado; Martelli, Andrea

    2011-08-01

    Space systems technology & validation are characterized by long development times and high costs due to the complexity of design and the reliability sought after. One of the main aims should hence be to reduce times and costs of multi-disciplinary interactions while improving their effectiveness.Looking for a major leap ahead in this direction, Thales Alenia Space, started specific initiatives as part of the STEPSproject. STEPS ( istemi e ecnologie per l' s lorazione Spaziale) is a research project co- financed by PiedmontRegion and firms and universities of the Piedmont Aerospace District, aims at supporting the research and innovationactivities in the Space Exploration domain.STEPS is a three years technology research project (started in December 2008) with TAS Italia as Prime with 28partners (the three Piemonte Universities - PoliTO; UniTO; UniPMN, ALTEC, one research institute and 23 PiemonteSME).

  9. From ISS to Human Space Exploration: TAS-I contribution and perspectives

    NASA Astrophysics Data System (ADS)

    Messidoro, P.

    The paper describes the contribution of Thales Alenia Space Italia (TAS-I) in Torino to the Human Space Exploration starting from the participation to the International Space Station (ISS) up to the new perspectives in the fields of the Space Habitats, Transportation Systems and related technologies. The contribution of more than 50% of the habitable volume of the ISS is underlined through the actual projects MPLM, Columbus, NODE 2 and 3, Cupola, ATV, ISS Payloads, and future initiative such as PMM, Cygnus/PCM, ISS Exploitation and other ATV missions. The perspectives are introduced in terms of re-entry demo missions and advanced transportation systems like EXPERT and IXV together with technology programs relevant to Inflatable Habitats, Crew Collaborative Robotics, Regenerative Life Support, Landers, Pressurized Rovers, Advanced Thermo-mechanical materials and propulsion. The TAS-I involvement in local initiative as the regional co-funded project STEPS and the International Master SEEDS are also emphasized.

  10. FAME Process: A Dedicated Development and V&V Process for FDIR

    NASA Astrophysics Data System (ADS)

    Guiotto, Andrea; De Ferluc, Regis; Bozzano, Marco; Cimatti, Alessandro; Gario, Marco; Yushtein, Yuri

    2014-08-01

    In the frame of the European Space Agency (ESA) studies, Thales Alenia Space Italia has carryed out a research - FAME - in collaboration with Fondazione Bruno Kessler and Thales Alenia Space France. The objective of the FAME project was to define a dedicated FDIR development, verification and validation process that can address the issues and shortcomings of the current industrial FDIR development practices. The ultimate goal was to allow for the consistent and timely FDIR conception, development, and Verification & Validation. A parallel objective of the study was the development of a toolset supporting the Process and enabling a coherent definition, specification, development, and V&V of the FDIR functionalities. It started in September 2013 and ended in May 2014.

  11. From GOCE to the Next Generation Gravity Mission

    NASA Astrophysics Data System (ADS)

    Cesare, Stefano; Allasio, Andrea; Anselmi, Alberto; Dionisio, Sabrina; Mottini, Sergio; Parisch, Manilo; Massotti, Luca; Silvestrin, Pierluigi

    2015-03-01

    ESA’s gravity mission GOCE, carried out with extraordinary success between 2009 and 2013, was the result of more than twenty years of system studies and technology developments in which Thales Alenia Space Italia (TAS-I) always played a major role. Already while GOCE was being developed, ESA began promoting preparatory studies for a Next Generation Gravity Mission (NGGM). While GOCE aimed to provide a high resolution static map of Earth’s gravity, the objective of NGGM is long-term monitoring of the time-variable gravity field with high temporal and spatial resolution. The new mission implies new measurement techniques and instrumentation, a new mission scenario and different spacecraft design drivers. Despite the differences, however, the achievements of GOCE (demonstration of long-duration wide-band drag free control, ultra-sensitive accelerometers, stable noncryogenic temperature control in low earth orbit, etc.) stand as the basis on which the new mission is being created.

  12. New Facility for S/C Magnetic Cleanliness Program

    NASA Astrophysics Data System (ADS)

    Polirpo, A.; Cucca, M.

    2012-05-01

    Detailed magnetic cleanliness programs in space systems are mandatory, especially for Earth and interplanetary missions carrying magnetometers used for measuring magnetic fields or for a stringent attitude control. In order to cope with these demands, TAS-I (Thales Alenia Space - Italia) Torino, traditionally involved in the development and AIT (Assembly Integration and Test) of scientific satellites, has decided to enhance its actual own capability through the acquisition of a new MCF (Magnetic Cleanliness Facility), adequate to support testing of spacecraft with stringent magnetic requirements. The aim of this paper is to introduce the basic features of this facility and the foreseen capabilities. Such facility will first be used during the early stage of the program Bepi Colombo, and consistent advantages are expected with respect to the MCF used in TAS-I Torino in the past.

  13. Improving earthquake hazard assessments in Italy: An alternative to “Texas sharpshooting”

    NASA Astrophysics Data System (ADS)

    Peresan, Antonella; Panza, Giuliano F.

    2012-12-01

    The 20 May 2012 M = 6.1 earthquake that struck the Emilia region of northern Italy illustrates a common problem afflicting earthquake hazard assessment. It occurred in an area classified as "low seismic hazard" based on the current national seismic hazard map (Gruppo di Lavoro, Redazione della mappa di pericolosità sismica, rapporto conclusivo, 2004, http://zonesismiche.mi.ingv.it/mappa_ps_apr04/italia.html) adopted in 2006. That revision of the seismic code was motivated by the 2002 M = 5.7 earthquake that struck S. Giuliano di Puglia in central Italy, also a previously classified low-hazard area, resulting in damage and casualties. Previous code was updated in 1981-1984 after earlier maps missed the 1980 M = 6.5 Irpinia earthquake.

  14. Local adaptation within a hybrid species.

    PubMed

    Eroukhmanoff, F; Hermansen, J S; Bailey, R I; Sæther, S A; Sætre, G-P

    2013-10-01

    Ecological divergence among populations may be strongly influenced by their genetic background. For instance, genetic admixture through introgressive hybridization or hybrid speciation is likely to affect the genetic variation and evolvability of phenotypic traits. We studied geographic variation in two beak dimensions and three other phenotypic traits of the Italian sparrow (Passer italiae), a young hybrid species formed through interbreeding between house sparrows (P. domesticus) and Spanish sparrows (P. hispaniolensis). We found that beak morphology was strongly influenced by precipitation regimes and that it appeared to be the target of divergent selection within Italian sparrows. Interestingly, however, the degree of parental genetic contribution in the hybrid species had no effect on phenotypic beak variation. Moreover, beak height divergence may mediate genetic differentiation between populations, consistent with isolation-by-adaptation within this hybrid species. The study illustrates how hybrid species may be relatively unconstrained by their admixed genetic background, allowing them to adapt rapidly to environmental variation.

  15. Hardware, integration & support for the ASI BIRBA balloon campaigns since year 2000

    NASA Astrophysics Data System (ADS)

    Donati, A.; Petracchi, L.; Neri, G.; Zolesi, V.

    In the history of the space exploration, the stratospheric balloons have been among the first platforms used to carry out scientific experiments. The Italian Space Agency (ASI) has a long experience of missions with sounding balloons, managing the launch base of Trapani-Milo and executing launches over the Mediterranean sea with flight duration of about 24 hours. From year 2000 Kayser Italia (KI) have been commissioned by ASI to develop incubators for biology and physical science to be used for balloon missions, and to provide mission support during the balloon campaigns. On this basis KI developed the BIRBA incubator, that was used in four mission campaigns from 2000 to 2002. A large set of BIRBA incubators are currently available at ASI for carrying out new mission campaigns.

  16. [Serapeo Temple in Pozzuoli, Italy--the unique gauge for the sea (world ocean) level and the Earth surface temperature for over 2100 years].

    PubMed

    Karnaukhov, V N; Karnaukhov, A V

    2010-01-01

    The changes in the sea level relative to the position of the Serapeo Temple in Pozzuoly (Italia) over a period of 2100 years are discussed in the context of the well known periods of climate cooling off (Neoglacial, Little Ace Period) and climate warming (Middle Ages Optimum, Modern climate warming). It is noted that the rate of sea level lifting relative to the position of the Serapeo Temple in the modern phase of climate warming, which began the end of the 18th Century is approximately two times higher than in the previous phase of climate warming in the period from the fifth to the mid-tenth century A.D. This indicates that not only the natural cyclic component contributes to the mechanisms of Modern Climate warming but also the anthropogenic component of approximately equivalent power, which results from the waste of CO2 caused by the burning of fossilized fuels.

  17. ExoMars Mission Analysis and Design - Launch, Cruise and Arrival Analyses

    NASA Technical Reports Server (NTRS)

    Cano, Juan L.; Cacciatore, Francesco

    2007-01-01

    ExoMars is ESA s next mission to planet Mars. The probe is aimed for launch either in 2013 or in 2016. The project is currently undergoing Phase B1 studies under ESA management and Thales Alenia Space Italia project leadership. In that context, DEIMOS Space is responsible for the Mission Analysis and Design for the interplanetary and the entry, descent and landing (EDL) activities. The present mission baseline is based on an Ariane 5 or Proton M launch in 2013 of a spacecraft Composite bearing a Carrier Module (CM) and a Descent Module (DM). A back-up option is proposed in 2016. This paper presents the current status of the interplanetary mission design from launch up to the start of the EDL phase.

  18. ENEIDE: An experiment of a spaceborne, L1/L2 integrated GPS/WAAS/EGNOS receiver

    NASA Astrophysics Data System (ADS)

    Zin, A.; Landenna, S.; Conti, A.; Marradi, L.; Di Raimondo, M. S.

    2007-09-01

    The ENEIDE mission consisted of 22 scientific experiments that were carried out on the Soyuz and on the International Space Station (ISS) during the flight of the Soyuz 10S to the ISS in April 2005. Among these experiments there was the ENEIDE instrument, which gave the name to the whole mission. ENEIDE is a space-qualified, dual-frequency, integrated GPS/WAASEGNOS receiver aimed to the verification of the tracking of GPS plus the augmentation systems from space. The receiver is built by Thales Alenia Space-Italia, Milan plant (formerly Laben), on the basis of the space-qualified dual-frequency receiver LAGRANGE, that will be a payload of several ESA and Italian Space Agency missions like ESA's GOCE or the Italian COSMO SKYMED constellation to cite few examples. This paper addresses the first results of the ENEIDE flight data analysis.

  19. "SeismoSAT" project results in connecting seismic data centres via satellite

    NASA Astrophysics Data System (ADS)

    Pesaresi, Damiano; Lenhardt, Wolfgang; Rauch, Markus; Živčić, Mladen; Steiner, Rudolf; Bertoni, Michele

    2015-04-01

    Since 2002 the OGS (Istituto Nazionale di Oceanografia e di Geofisica Sperimentale) in Udine (Italy), the Zentralanstalt für Meteorologie und Geodynamik (ZAMG) in Vienna (Austria), and the Agencija Republike Slovenije za Okolje (ARSO) in Ljubljana (Slovenia) are using the Antelope software suite as the main tool for collecting, analyzing, archiving and exchanging seismic data in real time, initially in the framework of the EU Interreg IIIa Italia-Austria project "Trans-national seismological networks in the South-Eastern Alps". The data exchange has proved to be effective and very useful in case of seismic events near the borders between Italy, Austria and Slovenia, where the poor single national seismic networks coverage precluded a correct localization, while the usage of common data from the integrated networks improves considerably the overall reliability of real time seismic monitoring of the area. Up to now the data exchange between the seismic data centres relied on internet: this however was not an ideal condition for civil protection purposes, since internet reliability is poor. For this reason in 2012 the Protezione Civile della Provincia Autonoma di Bolzano in Bolzano (Italy) joined OGS, ZAMG and ARSO in the Interreg IV Italia-Austria project "SeismoSAT" aimed in connecting the seismic data centres in real time via satellite. As already presented in the past, the general technical schema of the project has been approved, data bandwidths and monthly volumes required have been quantified, the common satellite provider has been selected and the hardware has been purchased and installed. We will here illustrate the SeismoSAT project final tests and results.

  20. "SeismoSAT" project state of the art: connecting seismic data centres via satellite

    NASA Astrophysics Data System (ADS)

    Pesaresi, Damiano; Lenhardt, Wolfgang; Rauch, Markus; Zivcic, Mladen; Steiner, Rudolf; Bertoni, Michele

    2014-05-01

    Since 2002 the OGS (Istituto Nazionale di Oceanografia e di Geofisica Sperimentale) in Udine (Italy), the Zentralanstalt für Meteorologie und Geodynamik (ZAMG) in Vienna (Austria), and the Agencija Republike Slovenije za Okolje (ARSO) in Ljubljana (Slovenia) are using the Antelope software suite as the main tool for collecting, analyzing, archiving and exchanging seismic data in real time, initially in the framework of the EU Interreg IIIa Italia-Austria project "Trans-national seismological networks in the South-Eastern Alps". The data exchange has proved to be effective and very useful in case of seismic events near the borders between Italy, Austria and Slovenia, where the poor single national seismic networks coverage precluded a correct localization, while the usage of common data from the integrated networks improves considerably the overall reliability of real time seismic monitoring of the area. At the moment the data exchange between the seismic data centres relies on internet: this however is not an ideal condition for civil protection purposes, since internet reliability is poor. For this reason in 2012 the Protezione Civile della Provincia Autonoma di Bolzano in Bolzano (Italy) joined OGS, ZAMG and ARSO in the Interreg IV Italia-Austria project "SeismoSAT" aimed in connecting the seismic data centres in real time via satellite. As it will be illustrated, the general technical schema of the project has been approved, data bandwidths and monthly volumes required have been quantified, the common satellite provider has been selected, the hardware has been purchased and installed, and the all SeismoSAT project is in testing phase.

  1. [National epidemiological surveillance systems of mesothelioma cases].

    PubMed

    Ferrante, Pierpaolo; Binazzi, Alessandra; Branchi, Claudia; Marinaccio, Alessandro

    2016-01-01

    INTRODUZIONE: sebbene la relazione causale tra esposizione ad amianto e malattie neoplastiche sia ben nota, in molti Paesi il consumo del materiale è ancora rilevante e crescente. A causa della lunga latenza, nei Paesi dove è stato bandito (come in Italia) è oggi in corso un'epidemia di malattie correlate ad amianto. OBIETTIVI: descrivere i sistemi di sorveglianza dei mesoteliomi attivi nel mondo mediante un'analisi comparativa. è stata condotta una revisione bibliografica della letteratura disponibile sui sistemi di sorveglianza epidemiologica dei mesoteliomi attivi nel mondo, comparando metodi e risultati disponibili. RISULTATI: sistemi di ricerca dei casi incidenti e di analisi anamnestica dei soggetti ammalati sono attivi solo in Italia, Francia e Corea del Sud. I Paesi presso i quali sono attivi sistemi di rilevazione e controllo dei casi incidenti di mesotelioma sono quelli in cui vige il bando dell'amianto e che hanno sperimentato consumi rilevanti in passato. Non sono stati istituiti sistemi epidemiologici di sorveglianza in molti Paesi dove il consumo di amianto è ancora importante (inclusi Russia, Cina, India e Brasile). CONCLUSIONI: si conferma l'importanza dei sistemi di sorveglianza epidemiologica dei mesoteliomi per la sanità pubblica, il sostegno alle politiche di welfare e la prevenzione dei rischi. Lo sviluppo di progetti per tendere a una maggiore uniformità nei metodi di ricerca dei casi, di classificazione delle diagnosi e dell'esposizione e nelle tecniche di analisi dei dati potrebbe consentire una maggiore fruibilità dei dati aggregati. La disponibilità di dati internazionali confrontabili può essere di stimolo all'adozione di provvedimenti di bando internazionale.

  2. The Large Binocular Telescope Project

    NASA Astrophysics Data System (ADS)

    Hill, J. M.

    1994-12-01

    The Large Binocular Telescope (LBT) Project has evolved from concepts first proposed in 1985. The present partners involved in the design and construction of this 2 x 8.4 meter binocular telescope are the University of Arizona, Italy represented by the Osservatorio Astronomico di Arcetri and the Research Corporation based in Tucson. These three partners have committed sufficient funds to build the enclosure and the telescope populated with a single 8.4 meter optical train --- approximately 40 million dollars (1989). Based on this commitment, design and construction activities are now moving forward. Additional partners are being sought. The next mirror to be cast at the Steward Observatory Mirror Lab in late fall 1995 will be the first borosilicate honeycomb primary for LBT. The baseline optical configuration of LBT includes wide field Cassegrain secondaries with optical foci above the primaries to provide a corrected one degree field at F/4. The infrared F/15 secondaries are a Gregorian design to allow maximum flexibility for adaptive optics. The F/15 secondaries are undersized to provide a low thermal background focal plane which is unvignetted over a 4 arcminute diameter field-of-view. The interferometric focus combining the light from the two 8.4 meter primaries will reimage two folded Gregorian focal planes to a central location. The telescope elevation structure accommodates swing arms which allow rapid interchange of the various secondary and tertiary mirrors. Maximum stiffness and minimal thermal disturbance continue to be important drivers for the detailed design of the telescope. The telescope structure accommodates installation of a vacuum bell jar for aluminizing the primary mirrors in-situ on the telescope. The detailed design of the telescope structure will be completed in 1995 by ADS Italia (Lecco) and European Industrial Engineering (Mestre). The final enclosure design is now in progress at M3 Engineering (Tucson) and ADS Italia. Construction

  3. Large Binocular Telescope Project

    NASA Astrophysics Data System (ADS)

    Hill, John M.

    1997-03-01

    The large binocular telescope (LBT) project have evolved from concepts first proposed in 1985. The present partners involved in the design and construction of this 2 by 8.4 meter binocular telescope are the University of Arizona, Italy represented by the Osservatorio Astrofisico di Arcetri and the Research Corporation based in Tucson, Arizona. These three partners have committed sufficient funds to build the enclosure and the telescope populated with a single 8.4 meter optical train -- approximately 40 million dollars (1989). Based on this commitment, design and construction activities are now moving forward. Additional partners are being sought. The next mirror to be cast at the Steward Observatory Mirror Lab in the fall of 1996 will be the first borosilicate honeycomb primary for LBT. The baseline optical configuration of LBT includes wide field Cassegrain secondaries with optical foci above the primaries to provide a corrected one degree field at F/4. The infrared F/15 secondaries are a Gregorian design to allow maximum flexibility for adaptive optics. The F/15 secondaries are undersized to provide a low thermal background focal plane which is unvignetted over a 4 arcminute diameter field-of-view. The interferometric focus combining the light from the two 8.4 meter primaries will reimage two folded Gregorian focal planes to a central location. The telescope elevation structure accommodates swing arms which allow rapid interchange of the various secondary and tertiary mirrors. Maximum stiffness and minimal thermal disturbance continue to be important drivers for the detailed design of the telescope. The telescope structure accommodates installation of a vacuum bell jar for aluminizing the primary mirrors in-situ on the telescope. The detailed design of the telescope structure will be completed in 1996 by ADS Italia (Lecco) and European Industrial Engineering (Mestre). The final enclosure design is now in progress at M3 Engineering (Tucson), EIE and ADS Italia

  4. The Large Binocular Telescope Project

    NASA Astrophysics Data System (ADS)

    Hill, J. M.

    1995-05-01

    The Large Binocular Telescope (LBT) Project has evolved from concepts first proposed in 1985. The present partners involved in the design and construction of this 2 x 8.4 meter binocular telescope are the University of Arizona, Italy represented by the Osservatorio Astrofisico di Arcetri and the Research Corporation based in Tucson. These three partners have committed sufficient funds to build the enclosure and the telescope populated with a single 8.4 meter optical train --- approximately 40 million dollars (1989). Based on this commitment, design and construction activities are now moving forward. Additional partners are being sought. The next mirror to be cast at the Steward Observatory Mirror Lab in spring of 1996 will be the first borosilicate honeycomb primary for LBT. The baseline optical configuration of LBT includes wide field Cassegrain secondaries with optical foci above the primaries to provide a corrected one degree field at F/4. The infrared F/15 secondaries are a Gregorian design to allow maximicrons flexibility for adaptive optics. The F/15 secondaries are undersized to provide a low thermal background focal plane which is unvignetted over a 4 arcminute diameter field-of-view. The interferometric focus combining the light from the two 8.4 meter primaries will reimage two folded Gregorian focal planes to a central location. The telescope elevation structure accommodates swing arms which allow rapid interchange of the various secondary and tertiary mirrors. Maximicrons stiffness and minimal thermal disturbance continue to be important drivers for the detailed design of the telescope. The telescope structure accommodates installation of a vacuum bell jar for aluminizing the primary mirrors in-situ on the telescope. The detailed design of the telescope structure will be completed in 1995 by ADS Italia (Lecco) and European Industrial Engineering (Mestre). The final enclosure design is now in progress at M3 Engineering (Tucson) and ADS Italia

  5. AT on Buried LPG Tanks Over 13 m3: An Innovative and Practical Solution

    NASA Astrophysics Data System (ADS)

    Di Fratta, Crescenzo; Ferraro, Antonio; Tscheliesnig, Peter; Lackner, Gerald; Correggia, Vincenzo; Altamura, Nicola

    In Italy, since 2005, techniques based on Acoustic Emission have been introduced for testing of underground LPG tanks up to 13 m3, according to the European standard EN 12818:2004. The testing procedure for these tanks plans to install one or more pairs of sensors inside the "dome" suited for the access to the valves and fittings of the tank, directly on the accessible metal shell. This methodology is not applicable for the underground LPG buried tanks, where it is necessary to install a larger number of AE sensors, in order to cover at 100% the whole tank shell, even at very deep positions. Already in 2004, the European standard EN 12820 (Appendix C - Informative)give the possibility to use Acoustic Emission testing of LPG underground or buried tanks with a capacity exceeding 13 m3, but no technique was specified for the application. In 2008, TÜV AUSTRIA ITALIA - BLU SOLUTIONS srl - Italian company of TÜV AUSTRIA Group - has developed a technique to get access at tank shell, where tank capacity is greater than 13 m3 and its' diameter greater than 3,5 m. This methodology was fully in comply with the provisions of the European Standard EN 12819:2010, becoming an innovative solution widely appreciated and is used in Italy since this time. Currently, large companies and petrochemical plants, at the occurrence of the tank's requalification, have engaged TÜV AUSTRIA ITALIA - BLU SOLUTIONS to install such permanent predispositions, which allow access to the tank shell - test object - with diameters from 4 to 8 m. Through this access, you can install the AE sensors needed to cover at 100% the tank surface and then to perform AE test. In an economic crisis period, this technique is proving a valid and practically applicable answer, in order to reduce inspection costs and downtime by offering a technically advanced solution (AT), increasing the safety of the involved operators, protecting natural resources and the environment.

  6. Efficacy of plant essential oils on postharvest control of rots caused by fungi on different stone fruits in vivo.

    PubMed

    Lopez-Reyes, Jorge Giovanny; Spadaro, Davide; Prelle, Ambra; Garibaldi, Angelo; Gullino, Maria Lodovica

    2013-04-01

    The antifungal activity of plant essential oils was evaluated as postharvest treatment on stone fruit against brown rot and grey mold rot of stone fruit caused by Monilinia laxa and Botrytis cinerea, respectively. The essential oils from basil (Ocimum basilicum), fennel (Foeniculum sativum), lavender (Lavandula officinalis), marjoram (Origanum majorana), oregano (Origanum vulgare), peppermint (Mentha piperita), rosemary (Rosmarinus officinalis), sage (Salvia officinalis), savory (Satureja montana), thyme (Thymus vulgaris), and wild mint (Mentha arvensis) were tested at two different concentrations on apricots (cv. Kyoto and cv. Tonda di Costigliole), nectarines (cv. Big Top and cv. Nectaross) and plums (cv. Italia and cv. TC Sun). The volatile composition of the essential oils tested was determined by gas chromatography-mass spectrometry analysis. The treatments containing essential oils from oregano, savory, and thyme at 1% (vol/vol) controlled both B. cinerea and M. laxa growing on apricots cv. Tonda di Costigliole and plums cv. Italia and cv. TC Sun; however, the same treatments were phytotoxic for the carposphere of nectarines cv. Big Top and cv. Nectaross. Treatments with 10% (vol/vol) essential oils were highly phytotoxic, notwithstanding their efficacy against the pathogens tested. The essential oils containing as major components α-pinene, p-cymene, carvacrol, and thymol showed similar results on stone fruit, so their antimicrobial activity and the phytotoxicity produced could be based on the concentration of their principal compounds and their synergistic activity. The efficacy of the essential oil treatments on control of fungal pathogens in postharvest depended on the fruit cultivar, the composition and concentration of the essential oil applied, and the length of storage.

  7. Consumption of functional foods in Europe; a systematic review.

    PubMed

    Özen, Asli E; Bibiloni, María del Mar; Pons, Antoni; Tur, Josep A

    2014-03-01

    Objetivo: Evaluar las diferencias en el consumo de alimentos funcionales entre los países europeos. Diseño: Revisión sistemática. La búsqueda bibliográfica se realizó en Medlars Online International Literature (MEDLINE), vía PubMed©, y Scopus. Se identificaron veintidós estudios que examinaron las diferencias en el consumo de alimentos funcionales entre los europeos. Resultados: Existen diferencias en la proporción de consumidores de alimentos funcionales entre los países europeos. Así, mientras los alimentos funcionales son muy populares en la mayoría de los países europeos como Finlandia, Suecia, Países Bajos, Polonia, España y Chipre, en algunos países como Dinamarca, Italia y Bélgica no lo son tanto. Un elevado porcentaje de adolescentes europeos mediterráneos (España y Chipre, pero no Italia) consume alimentos funcionales. La evaluación del consumo de alimentos funcionales en función del género es difícil, pues los resultados varían de estudio a estudio. Conclusiones: En los últimos años se ha extendido el consumo de alimentos funcionales en Europa, pero dicho consumo muestra grandes diferencias entre los europeos. Más investigaciones serán necesarias para averiguar las razones subyacentes tras estas diferencias y entender las necesidades de los consumidores de alimentos funcionales.

  8. Clinical evaluation of a novel dental implant system as single implants under immediate loading conditions - 4-month post-loading results from a multicentre randomised controlled trial.

    PubMed

    Esposito, Marco; Trullenque-Eriksson, Anna; Blasone, Rodolfo; Malaguti, Giuliano; Gaffuri, Cristiano; Caneva, Marco; Minciarelli, Armando; Luongo, Giuseppe

    preference regarding the two implant systems evaluated. Three operators preferred GENESIS implants, two had no preference and one preferred GENESIS in medium and soft bone and PRIMA in hard bone. No statistically significant differences were observed between the systems' implant types, although four GENESIS implants failed versus none of the PRIMA type. Longer follow-ups of wider patient populations are needed to better understand whether there is an effective advantage with one of the two implant designs. Conflict-of-interest statement: This research project was originally funded by Keystone Italia, Dental spa (Verona, Italy), the manufacturer of the implants evaluated in this investigation. 
 
However, when Keystone Italia received the data of the present manuscript, they refused to honour the financial agreement for the present publication. Therefore, no further follow-ups of this trial will be considered. A legal action was initiated against Keystone Italia. The data belonged to the authors and by no means was the manufacturer allowed to interfere with the conduct of the trial or the publication of the results.

  9. Switches in the Stress Field Induced by Fluid Overpressures Below a Low-Permeability Fault Zone

    NASA Astrophysics Data System (ADS)

    Collettini, C.; de Paola, N.; Goulty, N. R.

    2005-12-01

    The geological structure of Elba comprises thrust sheets stacked during the Apennine orogeny that are cross-cut by later Neogene extensional faults. The Zuccale fault is a gently east-dipping normal fault that offsets part of the thrust stack eastwards. Stratigraphic separations imply an offset of 7-8 km and exhumation of 3-6 km. A complex hydrofracture system exposed in the footwall of Palaeozoic schists and Triassic sediments at Punta di Zuccale consists of three vein sets: two vertical sets trending N-S and E-W and one sub-horizontal. The veins show a crack-and-seal texture and are characterized by mutual crosscutting relationships. The regional stress field throughout the period when the Zuccale fault was active, evidenced by numerous kinematic indicators, was extensional with the minimum principal stress oriented E-W, consistent with the N-S trending set of vertical hydrofractures. We interpret the vertical E-W trending and sub-horizontal hydrofractures as the result of overpressure development, due to exhumation, below the low-permeability, phyllosilicate-rich fault core. In our proposed mechanical model, exhumation reduced the vertical stress and also the horizontal stresses which responded poroelastically. The N-S trending vertical hydrofractures formed when the pore pressure exceeded the minimum principal stress by the tensile strength of the rock. Continued exhumation further reduced the vertical and N-S principal stresses, whilst the E-W principal stress remained equal to the pore pressure, until the pore pressure exceeded the N-S principal stress by the tensile strength of the rock, causing the E-W hydrofractures to form. Yet more exhumation further reduced the vertical stress, while the horizontal stresses remained equal to the pore pressure, until the pore pressure exceeded the vertical stress by the tensile strength of the rock, causing the sub-horizontal hydrofractures to form. The reduced normal effective stress across the fault encouraged fault

  10. A multi-model assessment of the impact of currents, waves and wind in modelling surface drifters and oil spill

    NASA Astrophysics Data System (ADS)

    De Dominicis, M.; Bruciaferri, D.; Gerin, R.; Pinardi, N.; Poulain, P. M.; Garreau, P.; Zodiatis, G.; Perivoliotis, L.; Fazioli, L.; Sorgente, R.; Manganiello, C.

    2016-11-01

    Validation of oil spill forecasting systems suffers from a lack of data due to the scarcity of oil slick in situ and satellite observations. Drifters (surface drifting buoys) are often considered as proxy for oil spill to overcome this problem. However, they can have different designs and consequently behave in a different way at sea, making it not straightforward to use them for oil spill model validation purposes and to account for surface currents, waves and wind when modelling them. Stemming from the need to validate the MEDESS4MS (Mediterranean Decision Support System for Marine Safety) multi-model oil spill prediction system, which allows access to several ocean, wave and meteorological operational model forecasts, an exercise at sea was carried out to collect a consistent dataset of oil slick satellite observations, in situ data and trajectories of different type of drifters. The exercise, called MEDESS4MS Serious Game 1 (SG1), took place in the Elba Island region (Western Mediterranean Sea) during May 2014. Satellite images covering the MEDESS4MS SG1 exercise area were acquired every day and, in the case an oil spill was observed from satellite, vessels of the Italian Coast Guard (ITCG) were sent in situ to confirm the presence of the pollution. During the exercise one oil slick was found in situ and drifters, with different water-following characteristics, were effectively deployed into the oil slick and then monitored in the following days. Although it was not possible to compare the oil slick and drifter trajectories due to a lack of satellite observations of the same oil slick in the following days, the oil slick observations in situ and drifters trajectories were used to evaluate the quality of MEDESS4MS multi-model currents, waves and winds by using the MEDSLIK-II oil spill model. The response of the drifters to surface ocean currents, different Stokes drift parameterizations and wind drag has been examined. We found that the surface ocean currents

  11. Beach changes from sediment delivered by streams to pocket beaches during a major flood

    NASA Astrophysics Data System (ADS)

    Pranzini, Enzo; Rosas, Valentina; Jackson, Nancy L.; Nordstrom, Karl F.

    2013-10-01

    The significance of sediment delivered via storm-associated stream discharge in altering sediment characteristics, beach form, and volume is evaluated on pocket beaches with different basin characteristics and wave exposures. The focus is on changes on three beaches on Elba Island, Italy caused by a flood event in September 2002 that had an estimated recurrence interval of 200 years. Beach profiles and foreshore sediment samples were gathered in 1999 and 2000 to identify pre-storm characteristics, in September 2002 to reveal the immediate effects of the storm, and in 2003 and 2004 to reveal post-storm recovery. Foreshore sediments were finer and better sorted and contained no pebbles prior to the flood. Coarsening of the sand and granule fraction was evident after the flood, along with pebble accumulations, especially near major streams. Mean size, sorting values and percent pebbles one and two years after the flood were generally greater than pre-flood conditions but less than immediately after the flood. Beach profiles reveal conspicuous erosion immediately after the flood, when sediment delivered by streams is transported to subaqueous deltas. Thereafter, sediment moves onshore and alongshore to adjacent beaches to restore subaerial volumes. The location of streams within a compartment, relative to the location of capes and headlands, is important in determining the movement of sediment added to the beach by streams. The sites are all sheltered from the highest-energy waves from the west, facilitating longshore transport to the west. Where the largest stream is located at the east end of a compartment, sediment discharged from it is source material for the downdrift beaches to the west. Where the largest stream is at the west end of the compartment, the ability to supply sediment to the beaches to the east is restricted. Hence, broad-scale geologic controls (headlands and capes) enhance or diminish the ability of streams to influence beach change throughout the

  12. Avalanche risk assessment - a multi-temporal approach, results from Galtür, Austria

    NASA Astrophysics Data System (ADS)

    Keiler, M.; Sailer, R.; Jörg, P.; Weber, C.; Fuchs, S.; Zischg, A.; Sauermoser, S.

    2006-07-01

    Snow avalanches pose a threat to settlements and infrastructure in alpine environments. Due to the catastrophic events in recent years, the public is more aware of this phenomenon. Alpine settlements have always been confronted with natural hazards, but changes in land use and in dealing with avalanche hazards lead to an altering perception of this threat. In this study, a multi-temporal risk assessment is presented for three avalanche tracks in the municipality of Galtür, Austria. Changes in avalanche risk as well as changes in the risk-influencing factors (process behaviour, values at risk (buildings) and vulnerability) between 1950 and 2000 are quantified. An additional focus is put on the interconnection between these factors and their influence on the resulting risk. The avalanche processes were calculated using different simulation models (SAMOS as well as ELBA+). For each avalanche track, different scenarios were calculated according to the development of mitigation measures. The focus of the study was on a multi-temporal risk assessment; consequently the used models could be replaced with other snow avalanche models providing the same functionalities. The monetary values of buildings were estimated using the volume of the buildings and average prices per cubic meter. The changing size of the buildings over time was inferred from construction plans. The vulnerability of the buildings is understood as a degree of loss to a given element within the area affected by natural hazards. A vulnerability function for different construction types of buildings that depends on avalanche pressure was used to assess the degree of loss. No general risk trend could be determined for the studied avalanche tracks. Due to the high complexity of the variations in risk, small changes of one of several influencing factors can cause considerable differences in the resulting risk. This multi-temporal approach leads to better understanding of the today's risk by identifying the

  13. Metabolic Capabilities of Microorganisms Involved in and Associated with the Anaerobic Oxidation of Methane.

    PubMed

    Wegener, Gunter; Krukenberg, Viola; Ruff, S Emil; Kellermann, Matthias Y; Knittel, Katrin

    2016-01-01

    In marine sediments the anaerobic oxidation of methane with sulfate as electron acceptor (AOM) is responsible for the removal of a major part of the greenhouse gas methane. AOM is performed by consortia of anaerobic methane-oxidizing archaea (ANME) and their specific partner bacteria. The physiology of these organisms is poorly understood, which is due to their slow growth with doubling times in the order of months and the phylogenetic diversity in natural and in vitro AOM enrichments. Here we study sediment-free long-term AOM enrichments that were cultivated from seep sediments sampled off the Italian Island Elba (20°C; hereon called E20) and from hot vents of the Guaymas Basin, Gulf of California, cultivated at 37°C (G37) or at 50°C (G50). These enrichments were dominated by consortia of ANME-2 archaea and Seep-SRB2 partner bacteria (E20) or by ANME-1, forming consortia with Seep-SRB2 bacteria (G37) or with bacteria of the HotSeep-1 cluster (G50). We investigate lipid membrane compositions as possible factors for the different temperature affinities of the different ANME clades and show autotrophy as characteristic feature for both ANME clades and their partner bacteria. Although in the absence of additional substrates methane formation was not observed, methanogenesis from methylated substrates (methanol and methylamine) could be quickly stimulated in the E20 and the G37 enrichment. Responsible for methanogenesis are archaea from the genus Methanohalophilus and Methanococcoides, which are minor community members during AOM (1-7‰ of archaeal 16S rRNA gene amplicons). In the same two cultures also sulfur disproportionation could be quickly stimulated by addition of zero-valent colloidal sulfur. The isolated partner bacteria are likewise minor community members (1-9‰ of bacterial 16S rRNA gene amplicons), whereas the dominant partner bacteria (Seep-SRB1a, Seep-SRB2, or HotSeep-1) did not grow on elemental sulfur. Our results support a functioning of AOM as

  14. Metallurgy, environmental pollution and the decline of Etruscan civilisation.

    PubMed

    Harrison, Adrian P; Cattani, Ilenia; Turfa, Jean M

    2010-01-01

    The Etruscans were justifiably famous in antiquity for their advanced metallurgy and for the rich mineral resources of their region (including La Tolfa, the Colline Metallifere, Mont'Amiata and Elba). We offer a new perspective on certain Iron Age and Archaic (ca. 1,000-480 BC: ) Etruscan industrial and habitation sites, and on the problem of heavy metal poisoning, still being investigated today, coincidentally in some of the same areas that originally saw Etruscan mines and workshops. This study investigates ancient sources, including literature and excavation reports, in the light of modern studies of heavy metal poisoning on human beings, plant and animal life. Furthermore, it is the first to use non-invasive Niton X-ray fluorescence analysis of samples of Etruscan (strictly ethnically Faliscan) hair (c. 350 BCE: ). The findings show the strong likelihood of heavy metal poisoning in areas of Etruscan metallurgical activity with the effects of this being responsible for or contributing to the abandonment of a number of these sites around the 6th century BC: . No thoroughly satisfactory explanation of this phenomenon has previously been offered. However, findings suggest that Faliscan women, represented by sample CG 2004-6-2, were not exposed to high levels of arsenic in life, which is not perhaps surprising for an urban aristocratic woman of the mid-4th century BC: . The reasons for the abandonment of several flourishing settlements are without doubt complex, and include political and social change. We suggest heavy metal contamination as an additional stimulus to the noted phenomenon of the peaceful abandonment, at the beginning, and at the end of the 6th century BC: , of sites in southern and northern Etruria such as Marsiliana d'Albegna (late 7th c.), Lago dell'Accesa, Acquarossa and Poggio Civitate-Murlo (late 6th c.). While the historical truth of the demise of Etruscan civilisation is much more complex, an interim set of related events, the desertion of

  15. Mucilage impact on gorgonians in the Tyrrhenian sea.

    PubMed

    Giuliani, S; Virno Lamberti, C; Sonni, C; Pellegrini, D

    2005-12-15

    The mucilage phenomenon has affected the Tuscan Archipelago since its first appearance (1991) in the Tyrrhenian Sea (Mediterranean Sea) [Innamorati M, Raddi E, Buzzichelli A, Melley S, Demoulin M. Le mucillaggini nel Mar Tirreno. Biol Mar Suppl Notiz 1992;1:23-26; Sartoni G, Sonni C. Tribonema marinum J. Feldmann e Acinetospora crinita (Carmichael) Sauvageau nelle formazioni mucillaginose bentoniche osservate sulle coste toscane nell'estate 1991. Inf Bot Ital 1991;23:23-30; Sartoni G, Cinelli F, Boddi S. Ruolo di Tribonema marinum J. Feldmann ed Acinetospora crinita (Carmichael) Sauvageau negli aggregati mucillaginosi bentonici delle coste toscane. Biol Mar Suppl Notiz 1993;1:31-34]. Seasonally, these mucous aggregates become very common in the benthic domain. The gorgonians are the most exposed organisms because they provide the best support for mucilage growth; indeed, their long branches positioned in orthogonally with respect to the current so as to capture plankton, also trap the filamentous mucilage present in the water. A 3-year monitoring programme at Capo Calvo (Island of Elba) was carried out in order to study the appearance of the mucilage phenomenon and its impact on three species of gorgonians (Eunicella cavolinii, Eunicella singularis, and Paramuricea clavata). The composition of mucilage and the gorgonian recovery capacity, when damaged, were investigated. During the first year of study (1999), no relevant interactions between gorgonians and mucilages were recorded. Instead, massive presence of mucilages causing different types of damage to the different gorgonian species investigated was recorded during the second (2000) and third year (2001). The type and the extent of the impact of mucilages also depend on the season. Three species of algae (Nematochrysopsis marina, Chrysonephos lewisii and Acinetospora crinita) constitute the principal components of the mucilaginous aggregates. In general, the first two species occur during the spring season

  16. A new regional RADAR network for nowcasting applications: the RESMAR achievements

    NASA Astrophysics Data System (ADS)

    Antonini, Andrea; Melani, Samantha; Mazza, Alessandro; Ortolani, Alberto; Gozzini, Bernardo; Corongiu, Manuela; Cristofori, Simone

    2013-04-01

    Monitoring weather phenomena from radar has an essential role in nowcasting applications. As one of the most useful sources of quantitative precipitation estimation, rainfall radar analysis can be a very useful research tool in supporting methods for rainfall forecasting. Its short-term prediction is often needed in various meteorological and hydrological applications where accurate prediction of rainfall is essential from national service and civil protection forecasting up to agriculture and urban issues. Very recently, Tuscany region (central Italy) is equipped with two X-band radars with a maximum range of 108 km, a beam width of 3° and a high spatial resolution (i.e., radial resolution up to 90m), located in Livorno and Cima del Monte (Elba island) sites. The first system is property of Livorno's port Authority, the second one of Consorzio LaMMA (Laboratory of Monitoring and Environmental Modelling for the sustainable development) who has installed it in the framework of "RESMAR - Environmental Resources in the MARitime Space" activities, a strategic project, financed in the framework of the European Cross-Border Cooperation Programme Italy-France "Maritime", coordinated by the Liguria Region Administration. Both systems are managed by LaMMA. The cross-border sharing of such relevant meteorological observation instruments and the integration of these data with existing tools and methodologies is intended to improve operational regional weather services in nowcasting activities and their impacts on the territory, as those related to LaMMA daily issues. This sharing is widely promoted within RESMAR project between the different partner regions (ARPA-Sardinia, Meteo-France and Liguria). The integration of these data with other complementary and ancillary measurements is also needed to increase the reliability and accuracy of radar measurements in view of both a better meteorological phenomena understanding and quantitative precipitation estimation. The use of

  17. Metabolic Capabilities of Microorganisms Involved in and Associated with the Anaerobic Oxidation of Methane

    PubMed Central

    Wegener, Gunter; Krukenberg, Viola; Ruff, S. Emil; Kellermann, Matthias Y.; Knittel, Katrin

    2016-01-01

    In marine sediments the anaerobic oxidation of methane with sulfate as electron acceptor (AOM) is responsible for the removal of a major part of the greenhouse gas methane. AOM is performed by consortia of anaerobic methane-oxidizing archaea (ANME) and their specific partner bacteria. The physiology of these organisms is poorly understood, which is due to their slow growth with doubling times in the order of months and the phylogenetic diversity in natural and in vitro AOM enrichments. Here we study sediment-free long-term AOM enrichments that were cultivated from seep sediments sampled off the Italian Island Elba (20°C; hereon called E20) and from hot vents of the Guaymas Basin, Gulf of California, cultivated at 37°C (G37) or at 50°C (G50). These enrichments were dominated by consortia of ANME-2 archaea and Seep-SRB2 partner bacteria (E20) or by ANME-1, forming consortia with Seep-SRB2 bacteria (G37) or with bacteria of the HotSeep-1 cluster (G50). We investigate lipid membrane compositions as possible factors for the different temperature affinities of the different ANME clades and show autotrophy as characteristic feature for both ANME clades and their partner bacteria. Although in the absence of additional substrates methane formation was not observed, methanogenesis from methylated substrates (methanol and methylamine) could be quickly stimulated in the E20 and the G37 enrichment. Responsible for methanogenesis are archaea from the genus Methanohalophilus and Methanococcoides, which are minor community members during AOM (1–7‰ of archaeal 16S rRNA gene amplicons). In the same two cultures also sulfur disproportionation could be quickly stimulated by addition of zero-valent colloidal sulfur. The isolated partner bacteria are likewise minor community members (1–9‰ of bacterial 16S rRNA gene amplicons), whereas the dominant partner bacteria (Seep-SRB1a, Seep-SRB2, or HotSeep-1) did not grow on elemental sulfur. Our results support a functioning of AOM

  18. Frictional Properties of a Low-Angle Normal Fault Under In Situ Conditions: Thermally-Activated Velocity Weakening

    NASA Astrophysics Data System (ADS)

    Niemeijer, André R.; Collettini, Cristiano

    2014-10-01

    The Zuccale fault is a regional, low-angle, normal fault, exposed on the Isle of Elba in central Italy that accommodated a total shear displacement of 6-8 km. The fault zone structure and fault rocks formed at <8 km crustal depth. The present-day fault structure is the final product of several deformation processes superposed during the fault history. In this study, we report results from a series of rotary shear experiments performed on 1-mm thick powdered gouges made from several fault rock types obtained from the Zuccale fault. The tests were done under conditions ranging from room temperature to in situ conditions (i.e., at temperatures up to 300 °C, applied normal stresses up to 150 MPa, and fluid-saturated.) The ratio of fluid pressure to normal stress was held constant at either λ = 0.4 or λ = 0.8 to simulate an overpressurized fault. The samples were sheared at a constant sliding velocity of 10 μm/s for at least 5 mm, after which a velocity-stepping sequence from 1 to 300 μm/s was started to determine the velocity dependence of friction. This can be represented by the rate-and-state parameter ( a-b), which was determined by an inversion of the data to the rate-and-state equations. Friction of the various fault rocks varies between 0.3 and 0.8, similar to values obtained in previous studies, and decreases with increasing phyllosilicate content. Friction decreases mildly with temperature, whereas normal stress and fluid pressure do not affect friction values systematically. All samples exhibited velocity strengthening, conditionally stable behavior under room temperature conditions and ( a- b) increased with increasing sliding velocity. In contrast, velocity weakening, accompanied by stick-slips, was observed for the strongest samples at 300 °C and sliding velocities below 10 μm/s. An increase in fluid pressure under these conditions led to a further reduction in ( a-b) for all samples, so that they exhibited unstable, stick-slip behavior at low

  19. Using intra annual density fluctuations and d13C to assess the impact of summer drought on Mediterranean ecosystem

    NASA Astrophysics Data System (ADS)

    Battipaglia, G.; Brand, W. A.; Linke, P.; Schaefer, I.; Noetzli, M.; Cherubini, P.

    2009-04-01

    Tree- ring growth and wood density have been used extensively as indicators of climate change, and tree-ring has been commonly applied as a proxy estimate for seasonal integration of temperatures and precipitation with annual resolution (Hughes 2002). While these relationships have been well established in temperate ecosystems (Fritts, 1976; Schweingruber, 1988, Briffa et al., 1998, 2004), in Mediterranean region dendrochronological studies are still scarce (Cherubini et al, 2003). In Mediterranean environment, trees may form intra-annual density fluctuations, also called "false rings" or "double rings" (Tingley 1937; Schulman 1938). They are usually induced by sudden drought events, occurring during the vegetative period, and, allowing intra-annual resolution, they may provide detailed information at a seasonal level, as well as species-specific sensitivity to drought. We investigated the variability of tree- ring width and carbon stable isotopes of a Mediterranean species, Arbutus unedo L., sampled on Elba island, (Tuscany, Italy). The samples were taken at two different sites, one characterized by wet and one by dry conditions. d13C was measured using Laser- Ablation- Combustion -GC-IRMS. Here, we present first results showing the impact of drought on tree growth and on false ring formation at the different sites and we underline the importance of using Laser Ablation to infer drought impact at the intra -annual level. Briffa KR, Schweingruber FH, Jones PD, Osborn TJ, Harris IC, Shiyatov SG, Vaganov EA, Grudd H (1998) Trees tell of past climates: but are they speaking less clearly today? Phil Transact Royal Soc London 353:65-73 Briffa KR, Osborn TJ, Schweingruber FH (2004) Large-scale temperature inferences from tree rings: a review. Glob Panet Change 40:11-26 Cherubini, P., B.L. Gartner, R. Tognetti, O.U. Bräker, W. Schoch & J.L. Innes. 2003. Identification, measurement and interpretation of tree rings in woody species from Mediterranean climates. Biol. Rev

  20. Morphology and dynamics of planetary laccoliths: a theoretical model to test for potential planetary intrusions

    NASA Astrophysics Data System (ADS)

    Michaut, C.

    2012-12-01

    Laccoliths are shallow magmatic intrusions which lead to the vertical displacement of the overburden, creating a characteristic dome-like topography. Laccoliths have been proposed to explain various geological features such as low-slope domes or floor-fractured craters at the surface of the Moon, Mars or Mercury. Here I show that planetary dome morphologies should provide indications of their processes of emplacement. Indeed, the dynamics of magma spreading below an elastic crust shows that the first spreading regime of an intrusion is controlled by the elastic response of the crust. In this elastic regime, the intrusion has a bell shape and the flow thickness evolves with flow length to the power 1 or 5/4, depending on the geometry. When the flow length becomes larger than a characteristic length scale, which depends on the flexural wavelength of the crust, the flow edges become steeper and the regime transitions to a gravity current regime. In the gravity current regime, the own flow weight controls the intrusion dynamics and shape, as is the case for surface lava flow, and the flow thickness remains constant or evolves slowly with flow length, depending on the geometry. Hence, co-genetic intrusive domes should exhibit a thickness to length power-law relationship with an exponent equal to 1 or 5/4, when the flow length is less than the elastic length scale, whereas the thickness of extrusive domes should remain constant or slowly evolve with flow length. The scaling law between flow length and thickness in the elastic regime fits observations on laccoliths at Elba Island, Italy. The shape and length scale derived from this model also fits the observed shape and characteristic length of terrestrial laccoliths. The morphologies of candidate intrusive domes at the surface of the Moon and Mars are then tested against this model and correspond to an emplacement at depth. The observed characteristic length of planetary intrusions increases as gravity decreases, as

  1. Hydrogeochemistry of regional aquifer systems from Tuscany (central Italy): the state of the art before the definition of a geochemical baseline

    NASA Astrophysics Data System (ADS)

    Nisi, Barbara; Battaglini, Raffaele; Raco, Brunella

    2013-04-01

    European Community Water Framework Directive (WFD) and its derivative regulations have recognized the urgent need to adopt specific measures against the contamination of water bodies by individual pollutants that may significantly affect the quality of water itself. Italian regulation takes into account the EU Directives, and charges the regional authorities to create monitoring networks and produce assessment reports on the contamination of groundwater. The knowledge of "natural baseline" for various dissolved elements in groundwaters on a regional scale becomes of primary importance to distinguish natural sources and anthropogenic inputs. The studied area includes the whole Tuscan regional district (central Italy) and covers an area of about 23,000 km2. From a geolithological point of view, Tuscan territory consists of several complexes outcropping regionally, the most typical features being the Mesozoic and Cenozoic carbonate and evaporitic formations, overlain by flysch sequences, as well as granite intrusions and volcanic rocks. Moreover, two geothermal areas (Larderello and Mt. Amiata), a large number of thermal springs and CO2-rich gas vents are mostly present in the central-southern part of Tuscany. Finally in southern Tuscany (e.g. Campiglia M.Ma, Mt. Amiata, Elba Island), mining districts, predominantly characterized by polimetallic sulphides ore deposits, were exploited since the Etruscan time. In this work statistical distribution models are used to develop summary statistics and estimate probabilities of exceeding water-quality standards according to the National Legislative Decree 152/06. Descriptive statistics on solute concentrations are based on geochemical data from the main Tuscan aquifers and investigated by the CNR-IGG (Institute of Geosciences and Earth Resources of Pisa, Italy) and Department of Earth Sciences (University of Florence, Italy). The data processing was carried out on 4,767 water samples collected from 1997 to 2009. According to

  2. Geological beauties and Landscape: new proposals to communicate the Geodiversity

    NASA Astrophysics Data System (ADS)

    Lugeri, Francesca; Farabollini, Piero; Amadio, Vittorio

    2015-04-01

    The European Landscape Convention proposes a concept of the landscape itself as an expression of the diversity of the natural, cultural and economic development of the population and identifies society as responsible of such a heritage. The landscape has a concrete value as natural resource and basis of functional processes that support life; it also has an important symbolic value: the consequences of the loss of landscape have been and still are devastating, even on a social level. The Landscape is object of human perceptions and, at the same time, can be considered the result of the interaction of many natural and cultural components: therefore it could become a "medium" to communicate the Earth Sciences to the whole society: the geo-morphological sciences are a powerful tool in order to explain and share a "sense of natural identity". The consciousness of being part of an ecosystem, is achieved through the knowledge and the experience of the environment. In order to create effective and efficient sensitivity in individuals and in communities, it is essential to explain the importance of geodiversity, which - integrated to bio diversity- contributes to the concept of "environmental diversity" essential balance of the planet and resource for the economy. The difficulty for the scientific communicators in reaching the wider public, requires new integrated solutions. A very positive experience is related to the project "GeoloGiro" geology at the Giro d'Italia, (realized thanks to a cooperation between ISPRA Geological Survey and the Italian Council of Geologists) which provides a TV time dedicated to make comprehensible the reasons of the geological and environmental beauties of the territory crossed by cyclists during each stage. A further project development, includes the transmission of a short cartoon in which a strange character - a pink dinosaur named GiROSAuro, cycling fan, pink as the jersey worn by the winners of the "Giro d 'Italia"- explains to the

  3. Phylogenetic Relationships and Genetic Variation in Longidorus and Xiphinema Species (Nematoda: Longidoridae) Using ITS1 Sequences of Nuclear Ribosomal DNA

    PubMed Central

    Ye, Weimin; Szalanski, Allen L.; Robbins, R. T.

    2004-01-01

    Genetic analyses using DNA sequences of nuclear ribosomal DNA ITS1 were conducted to determine the extent of genetic variation within and among Longidorus and Xiphinema species. DNA sequences were obtained from samples collected from Arkansas, California and Australia as well as 4 Xiphinema DNA sequences from GenBank. The sequences of the ITS1 region including the 3' end of the 18S rDNA gene and the 5' end of the 5.8S rDNA gene ranged from 1020 bp to 1244 bp for the 9 Longidorus species, and from 870 bp to 1354 bp for the 7 Xiphinema species. Nucleotide frequencies were: A = 25.5%, C = 21.0%, G = 26.4%, and T = 27.1%. Genetic variation between the two genera had a maximum divergence of 38.6% between X. chambersi and L. crassus. Genetic variation among Xiphinema species ranged from 3.8% between X. diversicaudatum and X. bakeri to 29.9% between X. chambersi and X. italiae. Within Longidorus, genetic variation ranged from 8.9% between L. crassus and L. grandis to 32.4% between L. fragilis and L. diadecturus. Intraspecific genetic variation in X. americanum sensu lato ranged from 0.3% to 1.9%, while genetic variation in L. diadecturus had 0.8% and L. biformis ranged from 0.6% to 10.9%. Identical sequences were obtained between the two populations of L. grandis, and between the two populations of X. bakeri. Phylogenetic analyses based on the ITS1 DNA sequence data were conducted on each genus separately using both maximum parsimony and maximum likelihood analysis. Among the Longidorus taxa, 4 subgroups are supported: L. grandis, L. crassus, and L. elongatus are in one cluster; L. biformis and L. paralongicaudatus are in a second cluster; L. fragilis and L. breviannulatus are in a third cluster; and L. diadecturus is in a fourth cluster. Among the Xiphinema taxa, 3 subgroups are supported: X. americanum with X. chambersi, X. bakeri with X. diversicaudatum, and X. italiae and X. vuittenezi forming a sister group with X. index. The relationships observed in this study

  4. Slam, a Service for Landslide Monitoring Based on EO-Data

    NASA Astrophysics Data System (ADS)

    Manunta, P.; Brugioni, M.; Casagli, N.; Colombo, D.; Deflorio, A. M.; Farina, P.; Ferretti, A.; Gontier, E.; Graf, K.; Haeberle, J.; Lateltin, O.; Meloni, E.; Mayoraz, R.; Montini, G.; Moretti, S.; Paganini, M.; Palazzo, F.; Spina, D.; Sulli, L.; Strozzi, T.

    2004-06-01

    Every year slope instabilities cause large socio-economic losses on life and property worldwide. Indeed, the casualties caused by mass movements are among the highest in the industrialized world. In this contest the SLAM project is aimed to the implementation of landslides mapping and monitoring service that can be integrated into the current landslide management procedures. The innovative aspect of the SLAM project is the integration of the SAR techniques and EO data with the in situ documentation currently in use for the landslide monitoring. In particular, SLAM is designed to realise three types of products: Landslide Motion Survey, Landslide Displacement Monitoring and Landslide Susceptibility Mapping. The realization of SLAM project, entirely funded by ESA, is carried out by an international Consortium led by Planetek Italia (I) and formed by other five partners: Tele-Rilevamento Europa (I), Gamma Remote Sensing (CH), Spacebel (B), Geotest (CH) and Earth Science Department of the University of Firenze (I). For the Italian service cases the interferometric analysis is based on the PS technique, developed and patented by the Politecnico di Milano (Italy) and improved by Tele-Rilevamento Europa. For the Swiss service cases, multi-pass SAR interferometry, including the Interferometric Point Target Analysis (IPTA), is applied by Gamma Remote Sensing.

  5. Mission STS-134: Results of Shape Memory Foam Experiment

    NASA Astrophysics Data System (ADS)

    Santo, Loredana; Quadrini, Fabrizio; Mascetti, Gabriele; Dolce, Ferdinando; Zolesi, Valfredo

    2013-10-01

    Shape memory epoxy foams were used for an experiment aboard the International Space Station (ISS) to evaluate the feasibility of their use for building light actuators and expandable/deployable structures. The experiment named I-FOAM was performed by an autonomous device contained in the BIOKON container (by Kayser Italia) which was in turn composed of control and heating system, battery pack and data acquisition system. To simulate the actuation of simple devices in micro-gravity conditions, three different configurations (compression, bending and torsion) were chosen during the memory step of the foams so as to produce their recovery on ISS. Micro-gravity does not affect the ability of the foams to recover their shape but it poses limits for the heating system design because of the difference in heat transfer on Earth and in orbit. A recovery about 70% was measured at a temperature of 110 °C for the bending and torsion configuration whereas poor recovery was observed for the compression case. Thanks to these results, a new experiment has been developed for a future mission by the same device: for the first time a shape memory composite will be recovered, and the actuation load during time will be measured during the recovery of an epoxy foam sample.

  6. Sea-Salt Aerosol Forecasts Compared with Wave and Sea-Salt Measurements in the Open Mediterranean Sea

    NASA Astrophysics Data System (ADS)

    Kishcha, P.; Starobinets, B.; Bozzano, R.; Pensieri, S.; Canepa, E.; Nickovie, S.; di Sarra, A.; Udisti, R.; Becagli, S.; Alpert, P.

    2012-03-01

    Sea-salt aerosol (SSA) could influence the Earth's climate acting as cloud condensation nuclei. However, there were no regular measurements of SSA in the open sea. At Tel-Aviv University, the DREAM-Salt prediction system has been producing daily forecasts of 3-D distribution of sea-salt aerosol concentrations over the Mediterranean Sea (http://wind.tau.ac.il/saltina/ salt.html). In order to evaluate the model performance in the open sea, daily modeled concentrations were compared directly with SSA measurements taken at the tiny island of Lampedusa, in the Central Mediterranean. In order to further test the robustness of the model, the model performance over the open sea was indirectly verified by comparing modeled SSA concentrations with wave height measurements collected by the ODAS Italia 1 buoy and the Llobregat buoy. Model-vs.-measurement comparisons show that the model is capable of producing realistic SSA concentrations and their day-today variations over the open sea, in accordance with observed wave height and wind speed.

  7. Optimum parameter for estimating phase fluctuations on transionospheric signals at high latitudes

    NASA Astrophysics Data System (ADS)

    Forte, Biagio; Materassi, Massimo; Alfonsi, Lucilla; Romano, Vincenzo; de Franceschi, Giorgiana; Spalla, Paolo

    2011-06-01

    Transionospheric radio signals may experience fluctuations in their amplitude and phase due to irregularity in the spatial electron density distribution, referred to as scintillation. Ionospheric scintillation is responsible for transionospheric signal degradation that can affect the performance of satellite based navigation systems. Usually, the scintillation activity is measured by means of indices such as the normalised standard deviation of the received intensity S4 and the standard deviation of the received phase σϕ typically calculated over 1 min of data. Data from a GPS scintillation monitor based on 50 Hz measurements recorded at Dirigibile Italia Station (Ny-Alesund, Svalbard), in the frame of the ISACCO project (De Franceschi et al., 2006) are used to investigate possible adoption of an alternative parameter for the estimate of phase fluctuations: i.e., the standard deviation of the phase rate of change Sϕ. This parameter is shown to better correlate with S4 being much less detrending dependent than σϕ. The couple (S4, Sϕ) should be then considered a more physical proxy of radio scintillation than the couple (S4, σϕ).

  8. Km3Net Italy - Seafloor network

    NASA Astrophysics Data System (ADS)

    Papaleo, Riccardo

    2016-04-01

    The KM3NeT European project aims to construct a large volume underwater neutrino telescope in the depths of the Mediterranean Sea. INFN and KM3NeT collaboration, thanks to a dedicated funding of 21.000.000 € (PON 2007-2013), are committed to build and deploy the Phase 1 of the telescope, composed of a network of detection units: 8 towers, equipped with single photomultiplier optical modules, and 24 strings, equipped with multi-photomultipliers optical modules. All the towers and strings are connected to the main electro optical cable by means of a network of junction boxes and electro optical interlink cables. Each junction box is an active node able to provide all the necessary power to the detection units and to guarantee the data transmission between the detector and the on-shore control station. The KM3NeT Italia project foresees the realization and the installation of the first part of the deep sea network, composed of three junction boxes, one for the towers and two for the strings. In July 2015, two junction boxes have been deployed and connected to the new cable termination frame installed during the same sea campaign. The third and last one will be installed in November 2015. The status of the deep sea network is presented together with technical details of the project.

  9. "SeismoSAT" project results in connecting seismic data centres via satellite

    NASA Astrophysics Data System (ADS)

    Pesaresi, Damiano; Lenhardt, Wolfgang; Rauch, Markus; Živčić, Mladen; Steiner, Rudolf; Bertoni, Michele; Delazer, Heimo

    2016-04-01

    Since 2002 the OGS (Istituto Nazionale di Oceanografia e di Geofisica Sperimentale) in Udine (Italy), the Zentralanstalt für Meteorologie und Geodynamik (ZAMG) in Vienna (Austria), and the Agencija Republike Slovenije za Okolje (ARSO) in Ljubljana (Slovenia) are collecting, analysing, archiving and exchanging seismic data in real time. Up to now the data exchange between the seismic data centres relied on internet: this however was not an ideal condition for civil protection purposes, since internet reliability is poor. For this reason, in 2012 the Protezione Civile della Provincia Autonoma di Bolzano in Bolzano (Italy) joined OGS, ZAMG and ARSO in the Interreg IV Italia-Austria project "SeismoSAT" (Progetto SeismoSAT, 2014) aimed in connecting the seismic data centres in real time via satellite. As already presented in the past, the general technical schema of the project has been outlined, data bandwidths and monthly volumes required have been quantified, the common satellite provider has been selected and the hardware has been purchased and installed. Right before the end of its financial period, the SeismoSAT project proved to be successful guaranteeing data connection stability between the involved data centres during an internet outage.

  10. Development of the Flight Hardware for the Experiment XENOPUS on the Kubik BIO4-Mission

    NASA Astrophysics Data System (ADS)

    Horn, Eberhard R.; Böser, Sybille; Franz, Markus; Gabriel, Martin; Hiesgen, Norbert; Kübler, Ulrich; Porciani, Massimiliano; Schwarzwälder, Achim; Zolesi, Valfredo

    2011-02-01

    The needs of developing aquatic animals depend on their age. For example, amphibian tadpole stages require regular food supply while embryos use their yolk as food source. Thus, life support systems have to be adapted to the different ages; an efficient control for water cleanness and steady food supply is mandatory for a safe flight in microgravity. A list of biological and technical requirements prompted the concept of the Dornier-Mini-System and the design for the Astrium SUPPLY Unit. These life support systems are connected with the Astrium miniaquarium that was used several times for the transport of small aquatic animals in space. Scientific experience from this concept was considered by Kayser Italia to design and develop a space suitable hardware. Its functionality was successfully demonstrated by the experiment XENOPUS that flew on the Soyuz TMA13/TMA12 mission in 2008. From 36 launched tadpoles, 35 returned back to Earth after the 12 days lasting space flight in physiologically stable conditions.

  11. Human Space Exploration architecture study in TAS-I

    NASA Astrophysics Data System (ADS)

    Perino, M. A.

    The international space exploration plans foresee in the next decades multiple robotic and human missions to Moon, Mars and asteroids. The US Space Exploration program addresses the objective "to explore space and extend a human presence across the Solar System". Main steps include the completion of the International Space Station and its utilization in support of space exploration goals, "as the launching point for missions beyond the Low Earth Orbit". Along a parallel matching path, Europe has developed a roadmap for exploration - Aurora - and has supported design activities on combined Moon-Mars Exploration Architectures. Thales Alenia Space - Italia has been involved in the major European activities related to exploration and it is currently analyzing the different exploration scenarios considered by the major Space Agencies with the objective to identify an international reference scenario for exploration taking into account the need to balance collaboration at international level due to the highly demanding nature of planetary exploration missions, and the development of autonomous key capabilities considered of strategic importance.

  12. Columbus stowage optimization by cast (cargo accommodation support tool)

    NASA Astrophysics Data System (ADS)

    Fasano, G.; Saia, D.; Piras, A.

    2010-08-01

    A challenging issue related to the International Space Station utilization concerns the on-board stowage, implying a strong impact on habitability, safety and crew productivity. This holds in particular for the European Columbus laboratory, nowadays also utilized to provide the station with logistic support. The volume exploitation has to be maximized, in compliance with the given accommodation rules. At each upload step, the stowage problem must be solved quickly and efficiently. This leads to the comparison of different scenarios to select the most suitable one. Last minute upgrades, due to possible re-planning, may, moreover arise, imposing the further capability to rapidly readapt the current solution to the updated status. In this context, looking into satisfactory solutions represents a very demanding job, even for experienced designers. Thales Alenia Space Italia has achieved a remarkable expertise in the field of cargo accommodation and stowage. The company has recently developed CAST, a dedicated in-house software tool, to support the cargo accommodation of the European automated transfer vehicle. An ad hoc version, tailored to the Columbus stowage, has been further implemented and is going to be used from now on. This paper surveys the on-board stowage issue, pointing out the advantages of the proposed approach.

  13. Non-linear spacecraft component parameters identification based on experimental results and finite element modelling

    NASA Astrophysics Data System (ADS)

    Vismara, S. O.; Ricci, S.; Bellini, M.; Trittoni, L.

    2016-06-01

    The objective of the present paper is to describe a procedure to identify and model the non-linear behaviour of structural elements. The procedure herein applied can be divided into two main steps: the system identification and the finite element model updating. The application of the restoring force surface method as a strategy to characterize and identify localized non-linearities has been investigated. This method, which works in the time domain, has been chosen because it has `built-in' characterization capabilities, it allows a direct non-parametric identification of non-linear single-degree-of-freedom systems and it can easily deal with sine-sweep excitations. Two different application examples are reported. At first, a numerical test case has been carried out to investigate the modelling techniques in the case of non-linear behaviour based on the presence of a free-play in the model. The second example concerns the flap of the Intermediate eXperimental Vehicle that successfully completed its 100-min mission on 11 February 2015. The flap was developed under the responsibility of Thales Alenia Space Italia, the prime contractor, which provided the experimental data needed to accomplish the investigation. The procedure here presented has been applied to the results of modal testing performed on the article. Once the non-linear parameters were identified, they were used to update the finite element model in order to prove its capability of predicting the flap behaviour for different load levels.

  14. Weight gain, body image and sexual function in young patients treated with contraceptive vaginal ring. A prospective pilot study.

    PubMed

    Morotti, Elena; Casadio, Paolo; Guasina, Francesca; Battaglia, Bruno; Mattioli, Mara; Battaglia, Cesare

    2017-08-01

    Oral contraceptives could induce mood changes. As far as our knowledge, there are no studies in literature that have examined the role of vaginal contraception in self-perceived body image. To evaluate the effects of intravaginal contraception on weight gain and perceived body image in relation with the Beck's Depression Inventory questionnaire (BDI) and the McCoy Female Sexuality Questionnaire (MFSQ). Twenty-one adult (18-35 years old) eumenorrheic (menstrual cycle of 25-35 days), lean (body mass index - BMI - of 19-25 kg/m(2)) women who were referred for hormonal contraception were administered the Stunkard Figure Rating Scale (FRS), BDI and MFSQ. Subjects were studied in basal condition and after 6 months of therapy with vaginal contraception (NuvaRing®; Organon-Schering-Plough Italia, Milan, Italy). BMI, FRS, MFSQ and BDI. After 6 months of therapy with NuvaRing®, both body weight (60.0 ± 8.3; p = 0.050) and BMI (22.1 ± 3.1; p = 0.028) slightly, but statistically, increased. FRS and BDI showed no differences after the vaginal contraception. Hormonal contraception was associated with a significant decrease in the two-factor Italian MFSQ score. Vaginal ring seems a good alternative to other hormonal contraceptive not significantly altering the female sexuality and not influencing the FRS and BDI.

  15. Segmental bioimpedance analysis in professional cyclists during a three week stage race.

    PubMed

    Marra, Maurizio; Da Prat, Barbara; Montagnese, Concetta; Caldara, Annarita; Sammarco, Rosa; Pasanisi, Fabrizio; Corsetti, Roberto

    2016-07-01

    Bioelectrical impedance analysis has been widely used in the clinical and sport areas because it is a safe, non-invasive, rapid and inexpensive technique that evaluates some electrical properties of the body, such as resistance (R), reactance (X c ) and phase angle (PhA). The aim of this study is to evaluate body composition changes in professional cyclists, participating at the Giro D'Italia 2012, a three week stage race, and in particular PhA modifications as an expression of fat free mass nutritional status. Data were collected at the beginning, in the middle and at the end of the competition. Body weight, circumferences, skinfold thickness and BIA variables (total and segmental body) were measured. Body composition, measured by skinfold thickness, changed during the competition: fat free mass increased, but not significantly, in the middle and at the end of the competition, whereas fat mass significantly decreased versus the baseline in the middle and at the end of the competition. The total PhA did not significantly change in the middle of the competition but was significantly reduced at the end. The arm PhA did not change significantly at both times of the competition, whereas a significant reduction was reported for leg PhA in the middle and at the end of the competition. These results suggest the use of bioimpedance analysis, in particular PhA measurement, to monitor athletes' fat free mass characteristics during medium- and long-term competitions.

  16. Phaeoacremonium italicum sp. nov., associated with esca of grapevine in southern Italy.

    PubMed

    Raimondo, Maria Luisa; Lops, Francesco; Carlucci, Antonia

    2014-01-01

    To date at least 42 Phaeoacremonium species are known throughout the world. These fungal pathogens are responsible for several syndromes that occur in wood of different hosts, 27 of which have been associated with decline and dieback diseases or esca of grapevine and have been abundantly isolated from necrotic wood of grapevines with Petri and esca disease in vineyards worldwide. During a survey carried out in five vineyards of the grapevine cultivar Italia, several symptomatic samples were collected. A collection of 28 Phaeoacremonium isolates was analyzed. The phylogenetic relationships of the isolates were determined through the study of the β-tubulin and actin gene sequences. Combining morphological, culture and molecular data, three known Phaeoacremonium spp. were found, namely Pm. aleophilum, Pm. parasiticum and Pm. scolyti. One new species is described. Phaeoacremonium italicum can be identified by the common occurrence of bundles of up to 13, conidiophores with up to seven septa, occasionally branched, percurrent rejuvenation and predominantly phialides of type II. This novel species thus is isolated for the first time from grapevine in Apulia (southern Italy). © 2014 by The Mycological Society of America.

  17. Forensic botany as a useful tool in the crime scene: Report of a case.

    PubMed

    Margiotta, Gabriele; Bacaro, Giovanni; Carnevali, Eugenia; Severini, Simona; Bacci, Mauro; Gabbrielli, Mario

    2015-08-01

    The ubiquitous presence of plant species makes forensic botany useful for many criminal cases. Particularly, bryophytes are useful for forensic investigations because many of them are clonal and largely distributed. Bryophyte shoots can easily become attached to shoes and clothes and it is possible to be found on footwear, providing links between crime scene and individuals. We report a case of suicide of a young girl happened in Siena, Tuscany, Italia. The cause of traumatic injuries could be ascribed to suicide, to homicide, or to accident. In absence of eyewitnesses who could testify the dynamics of the event, the crime scene investigation was fundamental to clarify the accident. During the scene analysis, some fragments of Tortula muralis Hedw. and Bryum capillare Hedw were found. The fragments were analyzed by a bryologists in order to compare them with the moss present on the stairs that the victim used immediately before the death. The analysis of these bryophytes found at the crime scene allowed to reconstruct the accident. Even if this evidence, of course, is circumstantial, it can be useful in forensic cases, together with the other evidences, to reconstruct the dynamics of events. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  18. Prognostic value of the reactive oxygen species in severe sepsis and septic shock patients: a pilot study.

    PubMed

    Montini, Luca; DE Sole, Pasquale; Pennisi, Mariano A; Rossi, Cristina; Scatena, Roberto; DE Pascale, Gennaro; Bello, Giuseppe; Cutuli, Salvatore L; Antonelli, Massimo

    2016-12-01

    Reactive oxygen species (ROS) have been shown to play a role in the pathophysiology of sepsis. The aim of this study was to investigate ROS production over time in critically ill with sepsis patients and its correlation with outcome. This was a pilot single-centre prospective, observational study of patients consecutively admitted to our 18-general ICU. Over a period of 6 months all the consecutive patients with recent-onset of severe sepsis or septic shock were enrolled. Clinical and demographic characteristics of all patients were recorded. ROMs (ROS metabolites), reduced sulfhydryl groups (SH) and plasmatic lactate levels were collected at enrollment in the study and then every 5-7 days over 28 days or until sepsis resolution or death during sepsis. ROMs were analysed spectrophotometrically by the d-ROMs test (Diacron-Italia). SH were assayed in plasma by Ellman's reaction by spectrophotometric method. Septic shock-related mortality was defined as death that occurred during the follow up period, when the signs of shock remained, and death could not be attributed to causes other than septic shock by the attending physician. Twenty-five patients were studied. The SOFA score and the plasmatic lactate levels significantly correlated with the ROMs plasmatic levels. The mortality rate was higher in patients whose ROMs plasmatic levels decreased during septic shock evolution. Serial measurements of the ROMs plasmatic levels together with the SOFA score and lactate levels could help to identify septic shock patients with a very high probability of death.

  19. The MATROSHKA Experiment - First Mission Results

    NASA Astrophysics Data System (ADS)

    Reitz, Guenther

    MATROSHKA is an ESA multi-user experiment unit on the International Space Station ISS for studies of depth dose distribution of the different components of the orbital radiation field at different sites of the organs, occurring in astronauts being exposed during an EVA. To accomplish that, the facility comprises an anthropomorphic phantom to simulate the human body, active and passive detectors for space radiation dosimetry, data acquisition and processing electronics and the overall mechanical housing and support structure for the MATROSHKA components. The development and manufacture was under ESA contract by DLR, Institute for Aerospace Medicine with sub-contractors Kayser Italia (Livorno) and DTM (Modena). MATROSHKA was launched within PROGRESS on January 29, 2004 and mounted shortly afterwards outside the Russian Zvezda Module of the Station. The time of outside exposure during this mission phase was 539 days. After that, the facility was returned into the Station for passive sensor exchange. After the first passive detector set was returned to ground with Soyuz for on-ground evaluation the facility is further used inside the station during two follow-on project phases. The MATROSHKA experiment delivered a unique set of data results from the evaluation of numerous detectors, such as Thermoluminescence detectors, plastic nuclear track detectors and silicon dosemeters. This paper intends to give besides a short overview of the instrumentation used inside the MATROSHKA facility selected results from the first exposure and describes the determination of organ dose equivalents from these results

  20. Signal optimization, noise reduction, and systematic error compensation methods in long-path DOAS measurements

    NASA Astrophysics Data System (ADS)

    Simeone, Emilio; Donati, Alessandro

    1998-12-01

    The increment of the exploitable optical path represents one of the most important efforts in the differential optical absorption spectroscopy (DOAS) instruments improvement. The methods that allow long path measurements in the UV region are presented and discussed in this paper. These methods have been experimented in the new Italian DOAS instrument - SPOT - developed and manufactured by Kayser Italia. The system was equipped with a tele-controlled optical shuttle on the light source unit, allowing background radiation measurement. Wavelength absolute calibration of spectra by means of a collimated UV beam from a mercury lamp integrated in the telescope has been exploited. Besides, possible thermal effects on the dispersion coefficients of the holographic grating have been automatically compensated by means of a general non-linear fit during the spectral analysis session. Measurements in bistatic configuration have been performed in urban areas at 1300 m and 2200 m in three spectral windows from 245 to 380 nm. Measurements with these features are expected in the other spectral windows on path lengths ranging from about 5 to 10 km in urban areas. The DOAS technique can be used in field for very fast measurements in the 245-275 nm spectral range, on path lengths up to about 2500 m.

  1. Oral liquid formulation of levothyroxine is stable in breakfast beverages and may improve thyroid patient compliance.

    PubMed

    Bernareggi, Alberto; Grata, Elia; Pinorini, Maria Teresa; Conti, Ario

    2013-12-13

    Patients on treatment with levothyroxine (T4) are informed to take this drug in the morning, at least 30 min before having breakfast. A significant decrease of T4 absorption was reported, in fact, when T4 solid formulations are taken with food or coffee. According to preliminary clinical study reports, administration of T4 oral solution appears to be less sensitive to the effect of breakfast beverages on oral bioavailability. In the present study, stability of T4 oral solution added to breakfast beverages was investigated. A 1 mL ampoule of single-dose Tirosint® oral solution (IBSA Farmaceutici Italia, Lodi, Italy) was poured into defined volumes of milk, tea, coffee, and coffee with milk warmed at 50 °C, as well as in orange juice at room temperature. Samples were sequentially collected up to 20 min and analyzed by validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods. The results of the study demonstrated that T4 is stable in all beverages after 20 min incubation. Demonstration of T4 stability is a prerequisite for a thorough evaluation of the effect of breakfast beverages on the bioavailability of T4 given as oral solution and for a better understanding of the reasons underlying a decreased T4 bioavailability administered as solid formulations.

  2. Giro, Tour, and Vuelta in the same season.

    PubMed

    Lucia, A; Hoyos, J; Santalla, A; Earnest, C P; Chicharro, J L

    2003-01-01

    The exercise volume and intensity are reported of a male professional cyclist (age 30; VO2max 75.0 ml/kg/min) who successfully completed the 2001 Giro d'Italia (May), Tour de France (July), and Vuelta a España (September). The total exercise time during the Giro, Tour, and Vuelta was 90 hours 44 minutes (5444 minutes), 88 hours 23 minutes (5303 minutes), and 72 hours 59 minutes (4379 minutes) respectively. Heart rate telemetry during the races allowed the exercise intensity to be classified into three phases: I, below the first ventilatory threshold (VT1); II, between VT1 and the second ventilatory threshold (VT2); III, above VT2. Compared with the Giro and Tour, the lower exercise volume of the Vuelta (about 20% less total time) was compensated for by a considerably lower and higher contribution of phases I and III respectively. As a result, the total load (volume x intensity) in the three races was comparable.

  3. Inheritance of downy mildew (Plasmopara viticola) and anthracnose (Sphaceloma ampelinum) resistance in grapevines.

    PubMed

    Poolsawat, O; Mahanil, S; Laosuwan, P; Wongkaew, S; Tharapreuksapong, A; Reisch, B I; Tantasawat, P A

    2013-12-13

    Downy mildew (Plasmopara viticola) and anthracnose (Sphaceloma ampelinum) are two of the major diseases of most grapevine (Vitis vinifera L.) cultivars grown in Thailand. Therefore, breeding grapevines for improved downy mildew and anthracnose resistance is crucial. Factorial crosses were made between three downy mildew and/or anthracnose resistant lines ('NY88.0517.01', 'NY65.0550.04', and 'NY65.0551.05'; male parents) and two or three susceptible cultivars of V. vinifera ('Black Queen', 'Carolina Black Rose', and/or 'Italia'; female parents). F1 hybrid seedlings were evaluated for downy mildew and anthracnose resistance using a detached/excised leaf assay. For both diseases, the general combining ability (GCA) variance among male parents was significant, while the variance of GCA among females and the specific combining ability (SCA) variance were not significant, indicating the prevalence of additive over non-additive gene actions. The estimated narrow sense heritabilities of downy mildew and anthracnose resistance were 55.6 and 79.2%, respectively, suggesting that downy mildew/anthracnose resistance gene(s) were highly heritable. The 'Carolina Black Rose x NY65.0550.04' cross combination is recommended for future use.

  4. Oral Liquid Formulation of Levothyroxine Is Stable in Breakfast Beverages and May Improve Thyroid Patient Compliance

    PubMed Central

    Bernareggi, Alberto; Grata, Elia; Pinorini, Maria Teresa; Conti, Ario

    2013-01-01

    Patients on treatment with levothyroxine (T4) are informed to take this drug in the morning, at least 30 min before having breakfast. A significant decrease of T4 absorption was reported, in fact, when T4 solid formulations are taken with food or coffee. According to preliminary clinical study reports, administration of T4 oral solution appears to be less sensitive to the effect of breakfast beverages on oral bioavailability. In the present study, stability of T4 oral solution added to breakfast beverages was investigated. A 1 mL ampoule of single-dose Tirosint® oral solution (IBSA Farmaceutici Italia, Lodi, Italy) was poured into defined volumes of milk, tea, coffee, and coffee with milk warmed at 50 °C, as well as in orange juice at room temperature. Samples were sequentially collected up to 20 min and analyzed by validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods. The results of the study demonstrated that T4 is stable in all beverages after 20 min incubation. Demonstration of T4 stability is a prerequisite for a thorough evaluation of the effect of breakfast beverages on the bioavailability of T4 given as oral solution and for a better understanding of the reasons underlying a decreased T4 bioavailability administered as solid formulations. PMID:24351573

  5. A numerical performance assessment of a commercial cardiopulmonary by-pass blood heat exchanger.

    PubMed

    Consolo, Filippo; Fiore, Gianfranco B; Pelosi, Alessandra; Reggiani, Stefano; Redaelli, Alberto

    2015-06-01

    We developed a numerical model, based on multi-physics computational fluid dynamics (CFD) simulations, to assist the design process of a plastic hollow-fiber bundle blood heat exchanger (BHE) integrated within the INSPIRE(TM), a blood oxygenator (OXY) for cardiopulmonary by-pass procedures, recently released by Sorin Group Italia. In a comparative study, we analyzed five different geometrical design solutions of the BHE module. Quantitative geometrical-dependent parameters providing a comprehensive evaluation of both the hemo- and thermo-dynamics performance of the device were extracted to identify the best-performing prototypical solution. A convenient design configuration was identified, characterized by (i) a uniform blood flow pattern within the fiber bundle, preventing blood flow shunting and the onset of stagnation/recirculation areas and/or high velocity pathways, (ii) an enhanced blood heating efficiency, and (iii) a reduced blood pressure drop. The selected design configuration was then prototyped and tested to experimentally characterize the device performance. Experimental results confirmed numerical predictions, proving the effectiveness of CFD modeling as a reliable tool for in silico identification of suitable working conditions of blood handling medical devices. Notably, the numerical approach limited the need for extensive prototyping, thus reducing the corresponding machinery costs and time-to-market.

  6. NASA Webworldwind: Multidimensional Virtual Globe for Geo Big Data Visualization

    NASA Astrophysics Data System (ADS)

    Brovelli, M. A.; Hogan, P.; Prestifilippo, G.; Zamboni, G.

    2016-06-01

    In this paper, we presented a web application created using the NASA WebWorldWind framework. The application is capable of visualizing n-dimensional data using a Voxel model. In this case study, we handled social media data and Call Detailed Records (CDR) of telecommunication networks. These were retrieved from the "BigData Challenge 2015" of Telecom Italia. We focused on the visualization process for a suitable way to show this geo-data in a 3D environment, incorporating more than three dimensions. This engenders an interactive way to browse the data in their real context and understand them quickly. Users will be able to handle several varieties of data, import their dataset using a particular data structure, and then mash them up in the WebWorldWind virtual globe. A broad range of public use this tool for diverse purposes is possible, without much experience in the field, thanks to the intuitive user-interface of this web app.

  7. Light Pollution at Mount Wilson: Effect of Lighting Technology Changes

    NASA Astrophysics Data System (ADS)

    Garstang, R. H.

    2000-05-01

    In an earlier paper (Bull. AAS. 30, 838, 1998; Mem. Soc. Astr. Italia, in press, 2000) I studied the effects of population growth and of smog on the historical growth of light pollution at Mount Wilson. I have now done some very crude calculations to evaluate the effect of changes in lighting technology - the most important change being from incandescent lamps to mercury vapor lamps to high pressure sodium lamps in street lighting. I am greatly indebted to George Eslinger, lately Director of the Bureau of Public Lighting of the City of Los Angeles, for information on the numbers and types of street lights in that City. The ratio of numbers of lamps of different kinds throughout the Los Angeles basin at any given date has been assumed to be the same as in the City. The contributions to the photon output in the B and V photometric bands have been estimated. The calculations show a rate of increase of the V brightness greater than that obtained if lighting changes are neglected. The B brightness shows a maximum during the period when mercury vapor street lighting predominated. I hope to refine my calculations when additional information becomes available.

  8. ToF-SIMS applied to historical archaeology in the Alps

    NASA Astrophysics Data System (ADS)

    Sodhi, R. N. S.; Mahaney, W. C.; Milner, M. W.

    2006-07-01

    The actual route Hannibal followed during the invasion of Italia in the Second Punic War is one of the major questions of antiquity, one that historians/archaeologists have long studied. There are six possible passes Hannibal could have used and one of the many bits of evidence in the ancient literature that might help answer this question is the location of fired rock, the result of a conflagration Hannibal is reputed to have employed to reduce the size of boulders in a two-tier blocking rockslide on the lee side (e.g. Italian) some distance down from the high col. The only route with fired rock along the roadway leading to the Po River Valley or the Dora Riparia is below the Col du Clapier, one of the possible northern routes. ToF-SIMS investigation of the 100-μm thick burned crust in hornblende schist interlaced with veins of quartz-feldspathic minerals yields various elements C, Mg, Na, Ca, Si, Ti, P, Al, Fe and their associated fragments. Hydrocarbon fragments are thought to be products of combustion whereas Ca and Na along with Mg-Fe silicates are derived from the country rock. Aeolian components along with clay minerals settled onto rock surfaces following firing. While the SIMS data clearly would not provide an age for the burnt rock, compositional evidence of the conflagration may relate to Hannibal's actual route.

  9. Optimal Solubility of Diclofenac β-Cyclodextrin in Combination with Local Anaesthetics for Mesotherapy Applications

    PubMed Central

    Tringali, Giuseppe

    2017-01-01

    Because of low injection volume, the recently marketed injectable solution of diclofenac in complex with β-cyclodextrin (Akis®, IBSA Farmaceutici Italia) is an ideal candidate for mesotherapy applications. In this study, we investigated the solubility of Akis, 25 and 50 mg/kg, in combination with various local anaesthetics (lidocaine, mepivacaine, bupivacaine, levobupivacaine, and ropivacaine) at different concentrations in aqueous vehicles (normal saline, sterile water, or bicarbonate). Final injection mixtures were classified as limpid, turbid, or milky at visual analysis under standardized conditions. We found that (i) the use of sterile water for injections or normal saline as vehicles to dilute Akis in combination with whatever local anaesthetic normally results in milky solutions and therefore is not recommended; (ii) using bicarbonate, optimal solubility was obtained combining Akis with lidocaine, both 1 and 2%, or mepivacaine, both 1 and 2%, whereas solutions were turbid in combination with bupivacaine, levobupivacaine, or ropivacaine. Thus, we recommend that Akis is used in combination with lidocaine or mepivacaine in a bicarbonate vehicle. PMID:28491114

  10. Illicit drug use in cluster headache patients and in the general population: a comparative cross-sectional survey.

    PubMed

    Rossi, Paolo; Allena, Marta; Tassorelli, Cristina; Sances, Grazia; Di Lorenzo, Cherubino; Faroni, Jessica V; Nappi, Giuseppe

    2012-10-01

    The rate of illicit drug use in cluster headache (CH) patients is unknown. Two hundred and ten CH patients (162 males and 48 females) attending two headache clinics provided information about their lifetime use (once or more in their lifetime, LTU), recent use (once or more in the past year, RU), and current use (once or more in the past 30 days, CU) of illicit drugs. General population data (IPSAD®Italia2007-2008) served as the control group. LTU of each illicit drug but hallucinogens, RU of cannabis, cocaine, amphetamines and ecstasy, and CU of cannabis and cocaine were significantly higher in the male CH patients than in the general population, whereas no difference was found between the CH women and the controls. In the CH group, 28.5% of patients reported having used illicit drugs for the first time after CH onset and 71.5% before CH onset. Compared with the controls, the male CH group showed a greater prevalence both of lifetime sustained intensive use of any illicit drug and of current intensive use of cannabis. The results of this study indicate that male CH patients are prone to overindulge in illicit drug use. This finding possibly reflects a common biological susceptibility that predisposes these subjects to CH and to addictive behaviour.

  11. Nalmefene in Alcohol Use Disorder Subjects with Psychiatric Comorbidity: A Naturalistic Study.

    PubMed

    Di Nicola, Marco; De Filippis, Sergio; Martinotti, Giovanni; De Risio, Luisa; Pettorruso, Mauro; De Persis, Simone; Maremmani, Angelo Giovanni Icro; Maremmani, Icro; di Giannantonio, Massimo; Janiri, Luigi

    2017-07-01

    Nalmefene is the first drug to be approved for reducing alcohol consumption in alcohol use disorder (AUD) patients at high drinking risk. In real-world settings, there is a high prevalence of concurrent psychiatric disorders in AUD subjects, with associated increased morbidity and worse prognosis. This study evaluated the use of nalmefene in AUD patients with stabilized psychiatric comorbidity previously treated unsuccessfully for alcohol dependence, and assessed craving reduction and safety. Sixty-five AUD outpatients treated with as-needed 18 mg nalmefene for 24 weeks were included. Primary outcome measures were: changes in heavy drinking days (HDDs) and total alcohol consumption (TAC, g/day). Secondary outcome measures were: changes in drinking risk level and craving (obsessive-compulsive drinking scale and visual analogue scale for craving). Forty-two AUD subjects (64.6%) had one or more stabilized psychiatric comorbidity. There was a significant reduction in HDDs, TAC and craving measures (p < 0.001), with no differences between subjects with and without psychiatric comorbidity. Nalmefene was safe and well tolerated in all patients. As-needed nalmefene reduced drinking and craving in AUD subjects with and without psychiatric comorbidity. These findings suggest that nalmefene is a valid therapeutic option in real-world clinical settings, where comorbid conditions are common, and has the potential to engage AUD patients who may otherwise not have sought help. Lundbeck Italia S.P.A.

  12. DTFT-1: Analysis of the first USV flight test

    NASA Astrophysics Data System (ADS)

    Russo, G.

    2009-11-01

    The first dropped transonic flight test (DTFT) of the USV Program, performed with Castor, the first of the two spacecrafts developed within the USV Program, was performed on Saturday 24th February 2007, from Tortolì Airport in Sardinia. At 8:30 a.m. the 340 000 m 3 stratospheric balloon lifted off from the East coast of Sardinia, bringing the flying test bed (FTB) up to 20.2 km before release within the isolated sea polygon controlled by Italian air force test range in Salto di Quirra (PISQ). The mission ended at 10:30 a.m. with the splash-down of the space vehicle. The flight itself was very good, with a nose-up manoeuvre under transonic conditions, reaching a maximum Mach as high as 1.08. The mission target was completely achieved as some 2 million measures were taken related to flight data, housekeeping, as well as 500 aerodynamic and structural experimental sensors. Unfortunately, the vehicle has been damaged more than expected during splash-down. Many national and international institutions and industries contributed to the mission carrying out, under the supervision and technical guide of CIRA: Italian Space Agency, Italian Air Force, Italian Navy, Italian Civil Aviation Authority, Italian Company for Air Navigation Services, Port Authorities, European Space Agency, Techno System Dev., Vitrociset, Carlo Gavazzi Space, Space Software Italia, Alcatel Alenia Space Italy, ISL-Altran Group. The paper reports the actual status of post-flight data analysis.

  13. Millie Hughes-Fulford, Scientist and Prior Astronaut

    NASA Image and Video Library

    2014-03-13

    CAPE CANAVERAL, Fla. - Researcher and former NASA payload specialist Millie Hughes-Fulford, of the Hughes-Fulford Laboratory, San Francisco, Calif., accepts the European Space Agency ESA T-cell experiment flight units being handed over in a Space Station Processing Facility laboratory at NASA's Kennedy Space Center in Florida. From left are Raimondo Fortezza of ESA, Hughes-Fulford, and Pier Luigi Ganga, Marco Vukich and Fabio Creati of Kayser Italia, manufacturer of the hardware. The immunology experiment will launch on SpaceX-3 and focus on the effects of microgravity on early T-cell signaling pathways. Current work aims to identify and compare the gene expression of microRNAs miRNAs during T-cell activation under normal gravity and in microgravity, and compare those patterns to changes seen in aging populations. The experiment will be the first flown on SpaceX funded by the National Institutes of Health. Dr. Hughes-Fulford flew aboard space shuttle mission STS-40 in June 1991, the first Spacelab mission dedicated to biomedical studies. For more information on the T-cell experiment, visit http://hughesfulfordlab.com and http://www.nasa.gov/ames/research/space-biosciences/t-cell-activation-in-aging-spacex-3/. Photo credit: NASA/Cory Huston

  14. Millie Hughes-Fulford, Scientist and Prior Astronaut

    NASA Image and Video Library

    2014-03-13

    CAPE CANAVERAL, Fla. - Researcher and former NASA payload specialist Millie Hughes-Fulford, of the Hughes-Fulford Laboratory, San Francisco, Calif., accepts the European Space Agency ESA T-cell experiment flight units being handed over in a Space Station Processing Facility laboratory at NASA's Kennedy Space Center in Florida. From left are Raimondo Fortezza of ESA, Hughes-Fulford, and Pier Luigi Ganga and Fabio Creati of Kayser Italia, manufacturer of the hardware. The immunology experiment will launch on SpaceX-3 and focus on the effects of microgravity on early T-cell signaling pathways. Current work aims to identify and compare the gene expression of microRNAs miRNAs during T-cell activation under normal gravity and in microgravity, and compare those patterns to changes seen in aging populations. The experiment will be the first flown on SpaceX funded by the National Institutes of Health. Dr. Hughes-Fulford flew aboard space shuttle mission STS-40 in June 1991, the first Spacelab mission dedicated to biomedical studies. For more information on the T-cell experiment, visit http://hughesfulfordlab.com and http://www.nasa.gov/ames/research/space-biosciences/t-cell-activation-in-aging-spacex-3/. Photo credit: NASA/Cory Huston

  15. Millie Hughes-Fulford, Scientist and Prior Astronaut

    NASA Image and Video Library

    2014-03-13

    CAPE CANAVERAL, Fla. - Researcher and former NASA payload specialist Millie Hughes-Fulford, of the Hughes-Fulford Laboratory, San Francisco, Calif., accepts the European Space Agency ESA T-cell experiment flight units being handed over in a Space Station Processing Facility laboratory at NASA's Kennedy Space Center in Florida. From left are Hughes-Fulford shaking hands with Pier Luigi Ganga of Kayser Italia, manufacturer of the hardware, with Raimondo Fortezza of ESA looking on. The immunology experiment will launch on SpaceX-3 and focus on the effects of microgravity on early T-cell signaling pathways. Current work aims to identify and compare the gene expression of microRNAs miRNAs during T-cell activation under normal gravity and in microgravity, and compare those patterns to changes seen in aging populations. The experiment will be the first flown on SpaceX funded by the National Institutes of Health. Dr. Hughes-Fulford flew aboard space shuttle mission STS-40 in June 1991, the first Spacelab mission dedicated to biomedical studies. For more information on the T-cell experiment, visit http://hughesfulfordlab.com and http://www.nasa.gov/ames/research/space-biosciences/t-cell-activation-in-aging-spacex-3/. Photo credit: NASA/Cory Huston

  16. Fortuitous FISH diagnosis of an interstitial microdeletion (5)(q31.1q31.2) in a girl suspected to present a cri-du-chat syndrome.

    PubMed

    Mosca, A L; Callier, P; Leheup, B; Marle, N; Jalloul, M; Coffinet, L; Feillet, F; Valduga, M; Jonveaux, P; Mugneret, F

    2007-06-15

    Constitutional interstitial deletions of 5q are relatively rare and most are poorly characterized cytogenetically. Consequently a definite karyotype-phenotype correlation is difficult to establish. We report on a new case of a girl presenting with an abnormal cry, upslanting palpebral fissures, hypertelorism, anteverted nostrils, microretrognathia, growth retardation, and an adenoid cyst at the base of the tongue. The first suspected diagnosis was cri-du-chat syndrome because of the mewing cry. Standard cytogenetic analyses were interpreted as normal, but FISH studies using the probe of cri-du-chat syndrome with the control probe EGR1 (5q31.2)/D5S23 (Abbott) revealed a 5q31.2 microdeletion which was then confirmed by CGH-array (Abbott). FISH studies using PACs and BACs clones (Rocchi, Italia) enabled us to characterize the breakpoints of the deleted region. Cytogenetic analysis with FISH studies revealed a normal karyotype with normal 5q31 region in both parents. This case is compared with the other cases reported in the literature.

  17. The magnitude of events following a strong earthquake: and a pattern recognition approach applied to Italian seismicity

    NASA Astrophysics Data System (ADS)

    Gentili, Stefania; Di Giovambattista, Rita

    2016-04-01

    In this study, we propose an analysis of the earthquake clusters occurred in Italy from 1980 to 2015. In particular, given a strong earthquake, we are interested to identify statistical clues to forecast whether a subsequent strong earthquake will follow. We apply a pattern recognition approach to verify the possible precursors of a following strong earthquake. Part of the analysis is based on the observation of the cluster during the first hours/days after the first large event. The features adopted are, among the others, the number of earthquakes, the radiated energy and the equivalent source area. The other part of the analysis is based on the characteristics of the first strong earthquake, like its magnitude, depth, focal mechanism, the tectonic position of the source zone. The location of the cluster inside the Italia territory is of particular interest. In order to characterize the precursors depending on the cluster type, we used decision trees as classifiers on single precursor separately. The performances of the classification are tested by leave-one-out method. The analysis is done using different time-spans after the first strong earthquake, in order to simulate the increase of information available as time passes during the seismic clusters. The performances are assessed in terms of precision, recall and goodness of the single classifiers and the ROC graph is shown.

  18. Upper layer current variability in the Central Ligurian Sea

    NASA Astrophysics Data System (ADS)

    Picco, P.; Cappelletti, A.; Sparnocchia, S.; Schiano, M. E.; Pensieri, S.; Bozzano, R.

    2010-10-01

    Long-time series of surface currents and meteorological parameters were analysed to estimate the variability of the upper layer circulation and the response to the local winds. Current meter data were collected by an upward-looking RDI Sentinel 300 kHz ADCP deployed in the Central Ligurian Sea (43°47.77' N; 9°02.85' E) near the meteo-oceanographic buoy ODAS Italia 1 for more than eight months, from 13th of September 2003 to 24th of May 2004. The ADCP sampled the upper 50 m of water column at 8 m vertical resolution and 1 h time interval; surface marine and atmospheric hourly averaged data were provided by the buoy. Currents in the sampled layer were mainly barotropic, directed North-West in accordance with the general circulation of the area, and had a mean velocity of about 18 cm/s and hourly mean peaks up to 80 cm/s. Most of the observed variability in the upper thermocline was determined by inertial currents and mesoscale activity due to the presence of the Ligurian Front. Local wind had a minor role in the near-surface circulation but induced internal waves propagating downward in the water column.

  19. Padus, Sandalus, Gens Fadiena. Underwater Surveys in Palaeo-Watercourses (ferrara District - Italy)

    NASA Astrophysics Data System (ADS)

    Bucci, G.

    2015-04-01

    In the ambit of our program of researches on ancient rivers in Ferrara hinterland (Italy), we have been joining a Scientific - Didactic Project between Soprintendenza per i Beni Archeologici dell'Emilia Romagna, Comune di Portomaggiore Assessorato alla Cultura, CMAS A.CDCI. - Confédération Mondiale des Activités Subaquatiques Federation ITA F07 - Associazione CMAS Diving Center Italia. The Project is focused on underwater archaeological surveys in ex quarry lakes, following the Rivers Padus and Sandalus between Voghiera, Gambulaga and Portomaggiore (Ferrara District). Here we are going to introduce our most recent results, after the last immersions and a 3D bathymetrical survey completed by echo-side scan sonar in Tramonto Lake at Gambulaga, explaining the connection with remote sensing investigations and direct surveys applied to underwater archaeology of the inland water. The main submerged structure individuated is a part of wooden dock on the left side of Padus, in front of the Necropolis of Fadieni (1st-3rd cent. A.D.). Thanks to the study of 183 finds coming from the lake, involving students and young collaborators of the Archaeological National Museum of Ferrara, we are reconstructing the ancient landscape between Proto-Imperial Age and Late Antique.

  20. Serum cardiac troponin T after repeated endurance exercise events.

    PubMed

    Bonetti, A; Tirelli, F; Albertini, R; Monica, C; Monica, M; Tredici, G

    1996-05-01

    Recently Dr. Rowe made a hypothesis according to which small areas of myocardial necrosis can be caused by microvascular spasm, related to high catecholamine concentrations and other mechanisms, following extraordinary unremitting endurance exercises or due to the cumulative effect of several endurance events. It was this last suggestion which prompted us to investigate 25 top cyclists, taking part in the 77th Giro d'Italia. Blood samples were obtained the day before the start of the competition and once a week thereafter until the end. We measured myoglobin, lactic dehydrogenase, total creatine kinase, creatine kinase isoenzyme MB and serum cardiac troponin T (Tn-T), a highly sensitive and specific method for the detection of myocardial injury. While at measuring time points which followed we found a significant increase in the serum indicators of muscle damage, compared with their values at the beginning of the race, creatine kinase isoenzyme MB did not rise significantly and cardiac Tn-T was found in the serum of only 5 athletes, repeatedly in some cases, but always below the cut off values considered as indicating myocardial ischemia. On the basis of the behaviour of creatine kinase isoenzyme MB and, above all, of cardiac Tn-T, we can conclude that heavy endurance exercises, repeated daily for 22 days, as was the case in our study, do not seem able to produce, in top athletes, permanent heart damage by means of acute myocardial injury.

  1. Site Characterization of Italian Strong Motion Recording Stations

    SciTech Connect

    Scasserra, Giuseppe; Lanzo, Giuseppe; Stewart, Jonathan P.; Kayen, Robert E.

    2008-07-08

    A dataset of site conditions at 101 Italian ground motion stations with recorded motions has been compiled that includes geologic characteristics and seismic velocities. Geologic characterization is derived principally from local geologic investigations by ENEL that include detailed mapping and cross sections. For sites lacking such detailed geologic characterization, the geology maps of the by Servizio Geologico d'Italia are used. Seismic velocities are extracted from the literature and the files of consulting engineers, geologists and public agencies for 33 sites. Data sources utilized include post earthquake site investigations (Friuli and Irpinia events), microzonation studies, and miscellaneous investigations performed by researchers or consulting engineers/geologists. Additional seismic velocities are measured by the authors using the controlled source spectral analysis of surface waves (SASW) method for 18 sites that recorded the 1997-1998 Umbria Marche earthquake sequence. The compiled velocity measurements provide data for 51 of the 101 sites. For the remaining sites, the average seismic velocity in the upper 30 m (V{sub s30}) is estimated using a hybrid approach. For young Quaternary alluvium, V{sub s30} an existing empirical relationship for California sites by Wills and Clahan (2006) is used, which we justify by validating this relationship against Italian data. For Tertiary Limestone and Italian Mesozoic rocks, empirical estimates of V{sub s30} are developed using the available data. This work is also presented in Scasserra et al. (2008: JEE, in review)

  2. Antioxidant and Anti-inflammatory Activities of Broccoli Florets in LPS-stimulated RAW 264.7 Cells

    PubMed Central

    Hwang, Joon-Ho; Lim, Sang-Bin

    2014-01-01

    Broccoli (Brassica oleracea var. italia) florets were extracted with 80% methanol and the extract was sequentially fractionated with n-hexane, ethyl acetate, n-butanol, and distilled water. The extract and the fractions were evaluated for total phenolic content, sulforaphane content, antioxidant activity, and anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. The total phenolic content and sulforaphane content of the ethyl acetate fraction (EF) were 35.5 mg gallic acid equivalents/g and 620.2 μg/g, respectively. These values were higher than those of the 80% methanol extract and organic solvent fractions. The oxygen radical absorbance capacity of the EF [1,588.7 μM Trolox equivalents (TE)/mg] was 11-fold higher than that of the distilled water fraction (143.7 μM TE/mg). The EF inhibited nitric oxide release from LPS-stimulated RAW 264.7 cells in a dose-dependent manner and inhibited IκB-α degradation and nuclear factor-κB activation in LPS-stimulated RAW 264.7 cells. In conclusion, the EF of broccoli florets exerted potent antioxidant and anti-inflammatory effects. PMID:25054107

  3. [Italian male nurses called to arms in World War II: the letters of the years of imprisonment].

    PubMed

    Gaetano, Rosa Maria; Milos, Roberto; Rossi, Ivana Maria; Rancati, Stefania

    2016-01-01

    During the Second World War the male staff of assistance in the Italia hospitals was called to arms.This work concerns the letters sent by the male nurses who were captured by the Germans and put in prison. The aim is to know whether their profession had somehow affected their living condition in jail and had favoured their release or not. 88 personal files of nurses on duty in Ospedale Maggiore and sent to the front during the period between 1940 and 1945 have been studied. The documents are kept in the historical archive of the Ospedale Maggiore of Milan and the research covered the period from December to January 2013. The sources have been analyzed according to Chabod's method of historical research (2012). 4 prisoners have been found among the 88 files of soldiers and handwritten letter has been selected for each one. These letters the attempt of the prisoners to reassure their loved ones emerges. Moreover, in the files of the prisoners' formal request for their release sent by hospital board were found. As a result one of the prisoners was released. This paper suggests that the fact of being a nurse in a hospital influenced the conditions during tha period of captivity. Much is still to be found to shed light on a dramatic period of our country and to restore the memory of the contribution given by the profession.

  4. Foundry waste recycling in moulding operations and in the ceramic industry.

    PubMed

    Zanetti, Maria Chiara; Fiore, Silvia

    2003-06-01

    An industrial treatment was performed by the Sasil plant of Brusnengo (Biella, Northern Italy), which is part of the Gruppo Minerali S.p.A. (Novara, Northern Italy), to consider the reclamation of bentonite bonded moulding sands obtained from the Teksid Italia S.p.A. cast iron foundry plant in Crescentino (Vercelli, Northern Italy). An evaluation of the fine particles produced by the wet-mechanical regeneration treatment was made with the purpose of proposing their recycling as binding agents in moulding operations in the cast iron foundry and for the production of tiles in the ceramic industry. The pre-mixed product sold by bentonite suppliers (35% coal dust and 65% bentonite, 0.15 Euro/kg) could be made from the recovered fine fraction below 0.025 mm with the addition of active clay and coal dust, thus obtaining a product that will have physico-chemical properties similar to those of calcic bentonite. The improvements due to the addition of the fine particles to the usually employed clay for tile production were also underlined from the results of several baking tests. The recovery and recycling of sands and fine particles obtained from the reclamation of bentonite moulding sands will lead to a saving of raw materials and landfill space, with economic and environmental advantages.

  5. Job stress: an in-depth investigation based on the HSE questionnaire and a multistep approach in order to identify the most appropriate corrective actions.

    PubMed

    De Sio, S; Cedrone, F; Greco, E; Di Traglia, M; Sanità, D; Mandolesi, D; Stansfeld, S A

    2016-01-01

    Psychosocial hazards and work-related stress have reached epidemic proportions in Europe. The Italia law introduced in 2008 the obligation for Italian companies to assess work related stress risk in order to protect their workers' safety and health. The purpose of our study was to propose an accurate measurement tool, using the HSE indicator tool, for more appropriate and significant work-related stress' prevention measures. The study was conducted on 204 visual display unit (VDU) operators: 106 male and 98 female. All subjects were administered the HSE questionnaire. The sample was studied through a 4 step process, using HSE analysis tool and a statistical analysis, based on the odds ratio calculation. The assessment model used demonstrated the presence of work related stress in VDU operators and additional "critical" aspects which had failed to emerge by the classical use of HSE analysis tool. The approach we propose allows to obtain a complete picture of the perception of work-related stress and can point out the most appropriate corrective actions.

  6. [Knowledge and common sense of nurses on the health's inequities: an exploratory study.

    PubMed

    Cotichelli, Giordano; Di Meo, Giorgia; Giampieri, Paolo

    2016-01-01

    Introduzione. I dati statistici per il 2015 parlano di un peggioramento generale delle condizioni di vita e di salute della popolazione in Italia. Le possibili ricadute chiamano l’infermiere ad un coinvolgimento in tema di disuguaglianze nella salute. Lo studio è stato realizzato con lo scopo di valutare quanto gli infermieri conoscono e percepiscono la correlazione fra le condizioni di salute della popolazione e le iniquità di sistema. Metodo. E’ stato condotto uno studio esplorativo attraverso un aggiornamento bibliografico rispetto a precedenti lavori e la somministrazione di questionari a campioni di convenienza di professionisti e studenti di infermieristica e valutazione dei risultati secondo la prospettiva del mixed method. Risultati. La bibliografia infermieristica presente sul piano quantitativo è molto limitata. Il questionario fornisce risposte utili alla valutazione della percezione delle disuguaglianze nella salute in termini di equità orizzontale e verticale. Conclusioni. La conoscenza delle disuguaglianze nella salute non può essere al margine dei lavori scientifici e della stessa letteratura professionale. E’ necessario ridurre il divario fra gli aspetti valoriali propri della professione, che riverberano nella percezione delle iniquità esistenti, e l’assunzione piena del sapere correlato ai determinanti socio-economici della salute e della malattia.

  7. Grape seed extracts modify the outcome of oxaliplatin in colon cancer cells by interfering with cellular mechanisms of drug cytotoxicity.

    PubMed

    Porcelli, Letizia; Iacobazzi, Rosa Maria; Quatrale, Anna Elisa; Bergamini, Carlo; Denora, Nunzio; Crupi, Pasquale; Antonacci, Donato; Mangia, Anita; Simone, Giovanni; Silvestris, Nicola; Azzariti, Amalia

    2017-08-01

    Grape seed extracts are commonly utilized as dietary supplements for their antioxidant properties, even from cancer patients. However, whether these natural extracts interfere with chemotherapeutics utilized in colon cancer treatment is still poorly investigated. The cytotoxicity of extracts from Italia and Palieri cultivars either alone or in combination with oxaliplatin was evaluated in colon cancer cells. Grape seed extracts displayed anti-proliferative activity depending on the concentration utilized through apoptosis induction. In combination, they affected the activation of Erk1/2 and counteracted the intrinsic and the extrinsic pathway of apoptosis, the DNA damage and the generation of ROS induced by oxaliplatin. Noteworthy grape seed extracts strongly enhanced the uptake of oxaliplatin into all cells, by affecting the cell transport system of platinum. The addition of these natural extracts to oxaliplatin strongly reduced the cellular response to oxaliplatin and allowed a huge accumulation of platinum into cells. Here, we shed light on the chemical biology underlying the combination of grape seed extracts and oxaliplatin, demonstrating that they might be detrimental to oxaliplatin effectiveness in colon cancer therapy.

  8. Light can rescue auxin-dependent synchrony of cell division in a tobacco cell line

    PubMed Central

    Qiao, Fei; Petrášek, Jan; Nick, Peter

    2010-01-01

    Pattern formation in plants has to cope with ambient variability and therefore must integrate environmental cues such as light. Synchrony of cell divisions was previously observed in cell files of tobacco suspension cultures, which represents a simple case of pattern formation. To develop cellular approaches for light-dependent patterning, light-responsive tobacco cell lines were screened from the cell line Nicotiana tabacum L. cv. Virginia Bright Italia 0 (VBI-0). The light responsive and auxin-autonomous cell line VBI-3 was isolated. As in the progenitor line VBI-0, cell divisions are synchronized in VBI-3 during exponential growth phase. This synchrony can be inhibited by 1-N-naphthylphthalamic acid, an auxin transport inhibitor, and this process was accompanied by the disassembly of actin filaments. However, the synchrony could be rescued when the cells were cultured under white light or with exogenous indolyl-3-acetic acid. The rescue was most efficient for continuous far-red light followed by continuous blue light, whereas continuous red light was least effective. These findings are discussed in the context of phytochrome-induced auxin biosynthesis and auxin-dependent synchrony of cell division. PMID:19884227

  9. Investigations on the leaf anatomy and ultrastructure of grapevine (Vitis vinifera) under heat stress.

    PubMed

    Ben Salem-Fnayou, Asma; Bouamama, Badra; Ghorbel, Abdelwahed; Mliki, Ahmed

    2011-08-01

    Leaf anatomical and ultrastructural responses of "Razegui" and "Muscat Italia" grapevine cultivars to high temperatures were studied under controlled conditions (T > 36°C), based on photonic and electron microscopy. Histological studies performed on leaves from heat-stressed and control grapevines revealed thicker leaf blades under high temperature conditions. Environmental scanning electron microscopy of leaf surfaces from both cultivars allowed observing sinuate epidermal cells on the leaves of grapevines cultivated under heat stress and irregular giant oblong pores on their adaxial surface. When observed by transmission electron microscopy, leaf cross sections in grapevines cultivated under high temperature conditions exhibited folded cuticle and cell wall on the adaxial epidermis layer. Therefore, significantly greater cell wall thicknesses were measured under heat stress than control conditions in both cultivars. Regarding chloroplasts, they were more globular in shape under heat stress compared with control conditions and had disorganized thylakoids with a reduced thickness of grana stacking. The size of starch granule decreased, while the number of plastoglobules increased with heat stress, indicating a reduced carbon metabolism and a beginning of senescence within the 3-month heat stress period. This study confirms widespread adaptive properties in two grapevine cultivars in response to high temperature stress.

  10. Online Damage Detection on Metal and Composite Space Structures by Active and Passive Acoustic Methods

    NASA Astrophysics Data System (ADS)

    Scheerer, M.; Cardone, T.; Rapisarda, A.; Ottaviano, S.; Ftancesconi, D.

    2012-07-01

    In the frame of ESA funded programme Future Launcher Preparatory Programme Period 1 “Preparatory Activities on M&S”, Aerospace & Advanced Composites and Thales Alenia Space-Italia, have conceived and tested a structural health monitoring approach based on integrated Acoustic Emission - Active Ultrasound Damage Identification. The monitoring methods implemented in the study are both passive and active methods and the purpose is to cover large areas with a sufficient damage size detection capability. Two representative space sub-structures have been built and tested: a composite overwrapped pressure vessel (COPV) and a curved, stiffened Al-Li panel. In each structure, typical critical damages have been introduced: delaminations caused by impacts in the COPV and a crack in the stiffener of the Al-Li panel which was grown during a fatigue test campaign. The location and severity of both types of damages have been successfully assessed online using two commercially available systems: one 6 channel AE system from Vallen and one 64 channel AU system from Acellent.

  11. Benign Prostatic Hyperplasia - An economic assessment of fixed combination therapy based on a literature review.

    PubMed

    Messina, Roberto; Mirone, Vincenzo

    2015-09-30

    FederAnziani Senior Italia and SIU - Italian Society of Urology - have decided to work together to draft a document focussing on Benign Prostatic Hyperplasia (BPH), and to stress the importance of adherence with pharmacological treatment in this setting, from both a scientific and a patient standpoint. Starting from a literature search, the two associations analysed to what extent an increase in treatment adherence amongst these patients influences hospital savings and to what extent therapy persistence levels are affected by monotherapy rather than free drug combinations. These estimates were performed only on patients taking medicinal products belonging to the 5 α-reductase inhibitors (5ARI) class that, although not indispensable, are the compounds that bring the greatest benefits, especially in the elderly and for which we know that every additional 30 days of therapy reduced the likelihood of acute urinary retention (AUR) and surgery by 14% and 11% respectively *. The results show that the use of fixed combination therapy would involve an increase in persistence due to the lower rate of patients abandoning treatment over time. Each 30 day-increment of 5ARI therapy, i.e. for an expenditure of 10.6 million euros extra per year for 5ARI medication, savings of approximately 24.3 million euros in hospital costs could be achieved.

  12. Biochemical and genetic polymorphisms for carboxylesterase and acetylesterase in grape clones of Vitis vinifera L. (Vitaceae) cultivars.

    PubMed

    Orasmo, Gleice Ribeiro; Oliveira-Collet, Sandra A; Lapenta, Ana Sílvia; de Fátima P S Machado, Maria

    2007-10-01

    Native polyacrylamide gel electrophoresis (PAGE) was employed to show the highest number of esterase loci and to detect alpha- and beta-esterase polymorphisms in leaf buds of Vitis vinifera cultivars. A total of 16 esterase isozymes were detected in leaf buds from 235 plants including Italia, Rubi, Benitaka, and Brasil cultivars. Biochemical characterization of the grape esterases using ester substrates revealed alpha-, beta-, and alpha/beta-esterases with inhibitor tests distinguishing both carboxylesterases (EST-2, EST-3, EST-5, EST-6, EST-7, EST-8, EST-9, EST-10, and EST-16 isozymes) and acetylesterases (EST-4, EST-11, EST-12, EST-13, EST-14, EST-15 isozymes). No allele variation for alpha-, beta-, and alpha/beta-esterases was detected; however, EST-3 alpha-carboxylesterase was absent in 61.7% of vines, and EST-4 alpha/beta-acetylesterase was absent in one vine of Rubi cv. Null EST-3 carboxylesterase phenotype (61.7%) cannot be explained in this article, but the high genetic polymorphism in four V. vinifera clones is a positive aspect for genetic selection and development of new clones with different characteristics.

  13. Distribution and abundance of fish larvae in the northern Ionian Sea (Eastern Mediterranean)

    NASA Astrophysics Data System (ADS)

    Granata, Antonia; Cubeta, Annaluce; Minutoli, Roberta; Bergamasco, Alessandro; Guglielmo, Letterio

    2011-09-01

    The purpose of this paper was to study the spatial distribution, abundance and composition of fish larvae in the northern Ionian Sea. Samples were collected to the 600 m depth with an electronic multinet BIONESS during the "INTERREG Italia-Grecia" oceanographic cruise carried out in March 2000 off the Apulian Italian coast. A total of 46 species of teleost early stages were collected, belonging to 38 genera and 22 families. Over 52% of the larvae identified were mesopelagic species, almost 27% were demersal and about 21% pelagic. A total of 307 myctophids, 69 clupeids and 61 gadid post-larvae dominated the community. Benthosema glaciale (mean 6.1 mm SL) was the most abundant species (21.6%), the most frequent in the samples (28.8%), and dominant in the whole study area (mean 1.4 ind/100 m3). Particular attention was given to the horizontal and vertical distribution and abundance of the three dominant post-larval species: Benthosema glaciale, Sprattus sprattus sprattus and Notoscopelus elongatus. The Pearson coefficient ( R = 0.734) showed a high correlation between total zooplankton and fish larval assemblages in terms of spatial distribution abundance values. Regarding the vertical distribution of fish larvae, Sorensen's index ( S = 0.69) showed that fish larvae and total zooplankton abundance peaks co-occurred along the water column.

  14. A Contribution to the Taxonomy of the Genus Xiphinema Cobb, 1913

    PubMed Central

    Cohn, E.; Sher, S. A.

    1972-01-01

    In a comparative study of different populations of Xiphinema, the significance of the female gonad structure in species determination is stressed, and monodelphic, pseudomonodelphic, and didelphic forms in the genus are defined. X. chambersi is redescribed and illustrated, X. ensiculiferum and X. krugi are redefined, and X. ensiculiferoides n.sp. and X. orthotenum n.sp. are described. Proposed new synonymies are: X. itanhaense = X. brasiliense; X. bulgariensis and X. conurum = X. italiae; X. ifacolum = X. basiri; X. macrostylum = X. ensiculiferum; X. truncatum = X. elongatum; and X. vulgare = X. setariae. X. yapoense is considered species inquirenda and X. obtusum a nomen dubium. The following eight subgenera of the genus Xiphinema are proposed: Radiphinema n. subg., Krugiphinema n. subg., Xiphinema n. subg., Elongiphinema n. subg., Halliphinema n. subg., Basiphinema n. subg., Rotundiphinema n. subg., and Diversiphinema n. subg. A key to the subgenera of Xiphinema is presented, plus a list of 50 species in the genus, their synonyms, and 10 species inquirendae. PMID:19319244

  15. Mid-term results of an uncemented femoral stem with modular neck options.

    PubMed

    Benazzo, Francesco; Rossi, Stefano M P; Cecconi, Davide; Piovani, Lucio; Ravasi, Flavio

    2010-01-01

    We prospectively assessed the results of 239 primary total hip replacements performed using a conical stem combined with modular necks of different lengths and inclinations (Modulus System, Lima Corporate San Daniele Del Friuli, Udine, Italia) in 222 patients (50 men, 172 women), undergoing surgery between October 2001 and December 2006 and presenting with anatomical deformities of the proximal femur and/or acetabulum, including developmental dysplasia (DDH), ankylosis, and sequelae of osteotomies or fractures. Such conditions can make hip replacement problematic. The mean age at the time of surgery was 57.6 years (22 ÷ 83). No patients were lost to follow-up. 3 femoral components underwent revision. At a mean of 5 years follow-up the Harris Hip Score showed a significant improvement, increasing from 35 preoperatively to a mean of 96.6. Using Kaplan-Meier analysis the survival rate at 5 years was 98.28%. The Modulus stem showed good mid-term results in terms of survival, as well as clinical and radiographic outcome.

  16. Grape seed extract triggers apoptosis in Caco-2 human colon cancer cells through reactive oxygen species and calcium increase: extracellular signal-regulated kinase involvement.

    PubMed

    Dinicola, Simona; Mariggiò, Maria Addolorata; Morabito, Caterina; Guarnieri, Simone; Cucina, Alessandra; Pasqualato, Alessia; D'Anselmi, Fabrizio; Proietti, Sara; Coluccia, Pierpaolo; Bizzarri, Mariano

    2013-09-14

    Grape seed extract (GSE) from Italia, Palieri and Red Globe cultivars inhibits cell growth and induces apoptosis in Caco-2 human colon cancer cells in a dose-dependent manner. In order to investigate the mechanism(s) supporting the apoptotic process, we analysed reactive oxygen species (ROS) production, intracellular Ca2+ handling and extracellular signal-regulated kinase (ERK) activation. Upon exposure to GSE, ROS and intracellular Ca2+ levels increased in Caco-2 cells, concomitantly with ERK inactivation. As ERK activity is thought to be essential for promoting survival pathways, inhibition of this kinase is likely to play a relevant role in GSE-mediated anticancer effects. Indeed, pretreatment with N-acetyl cysteine, a ROS scavenger, reversed GSE-induced apoptosis, and promoted ERK phosphorylation. This effect was strengthened by ethylene glycol tetraacetic acid-mediated inhibition of extracellular Ca2+ influx. ROS and Ca2+ influx inhibition, in turn, increased ERK phosphorylation, and hence almost entirely suppressed GSE-mediated apoptosis. These data suggested that GSE triggers a previously unrecognised ERK-based mechanism, involving both ROS production and intracellular Ca2+ increase, eventually leading to apoptosis in cancer cells.

  17. Crustal section based on CROP seismic data across the North Tyrrhenian Northern Apennines Adriatic Sea

    NASA Astrophysics Data System (ADS)

    Finetti, I. R.; Boccaletti, M.; Bonini, M.; Del Ben, A.; Geletti, R.; Pipan, M.; Sani, F.

    2001-12-01

    progressively flatten eastward. Upper parts of the west-verging eo-Alpine thrust blocks were truncated by the east-verging thrust faults of the Balearic stage. A deeper seismic reflector, attributed to the top of the asthenosphere, forms a mantle high below the Elba Island. From the Late Miocene to Present, the Corsica basin and western hinterland area were affected by extensional tectonics related to the Tyrrhenian opening, whereas compressional tectonics continued in the eastern hinterland and mostly on the eastward migrating foreland, with development of a second "lithospheric root" constituted by high-angle thrust faults. These faults give rise to a huge basement culmination below the main Apennines watershed. Impressive E-directed gravity-sliding of sedimentary blocks over their sloping basement occur, generating the Umbria-Marche shallow seismicity. Crustal shortening of the Apennines system amounts to 170 km, 14 km of which are due to the eo-Alpine stage, 71 km to the Balearic and 85 km to the Tyrrhenian one. In the frame of Africa-Europe convergence, the Tyrrhenian-Apennines tectonodynamics were mainly conditioned by the Mesozoic paleogeography.

  18. Footwall Extension During Low-Angle Normal Faulting

    NASA Astrophysics Data System (ADS)

    Smith, S. A.; Holdsworth, R. E.; Collettini, C.; Imber, J.

    2006-12-01

    Many previous studies have documented pervasive hangingwall deformation associated with low-angle normal faults (LANF) and metamorphic core complexes, attesting to significant horizontal extension above the evolving fault zone. However, on the Island of Elba, Italy, extension in the immediate footwall of the Zuccale LANF reaches 60%, involves a complex kinematic history, and locally exerts a strong influence on fault zone thickness and the internal distribution of fault rocks. The Zuccale LANF was active between c.13-4 Ma at a dip of 15° east, and slipped under a regional stress field characterized by vertical σ1 (also see Collettini et al. Session T36). Stratigraphic offsets suggest a displacement of 6-8km. The earliest set of extensional structures in the footwall formed as sub-horizontal or LANF-parallel semi-brittle cataclastic shears. These are crosscut by higher-angle brittle normal faults which often show listric (in 2D) or `spoon-shaped' (in 3D) geometries and can be broadly subdivided in to an older and younger set. The older faults currently dip on average 35° east and accommodated E-directed extension. They are crosscut and rotated by the youngest set of footwall faults which dip on average 60° east, but accommodated SSE-directed extension, possibly as a consequence of intrusion of the c.5.9 Ma Porto Azzurro pluton at shallow depths beneath the fault zone. Where the core of the Zuccale LANF is well exposed, high-angle footwall structures are observed to link directly into the base of the fault zone causing the fault core to increase in thickness from ~3 to ~8 metres. Synchronous movement along the main LANF and high-angle footwall structures is recorded by east-verging asymmetric folding of the fault rock foliation directly above footwall faults. Two observations indicate that these footwall faults have an important role to play throughout the history of the main LANF; 1. Early-formed fault rocks such as chlorite- and talc-rich phyllites have been

  19. Frictional properties of Zuccale Fault rocks from room temperature to in-situ conditions: results from high strain rotary shear experiments

    NASA Astrophysics Data System (ADS)

    Niemeijer, A. R.; Collettini, C.; Smith, S.; Spiers, C.

    2011-12-01

    The Zuccale fault is a regionally-important, low-angle normal fault, exposed on the Isle of Elba in Central Italy, that accommodated a total shear displacement of 6-8 km.The fault zone structure and fault rocks formed at less than 8 km crustal depth. The present-day fault structure is the final product of several deformation processes superposed during the fault history. Here, we focus on a series of highly foliated and phyllosilicate-rich fault rocks that represent the basal horizon of the detachment. Previous experimental work on foliated, intact samples, sheared in their in-situ microstructural (foliated) condition, demonstrated a markedly lower friction coefficient compared to homogeneously mixed powdered samples of the same material. We concluded from these experiments that the existence of a continuous, through-going foliation provides numerous planes of weakness on which shear deformation could be accommodated. However, these experiments were performed under room-dry and room temperature conditions. Moreover, the question remains as to how foliation is formed in these rocks in the first place. In this study, we report results from a series of preliminary rotary shear experiments performed on two fault rock types obtained from the Zuccale Fault. The tests were done under conditions ranging from room temperature to in-situ conditions (i.e. at temperatures up to 350 °C, applied normal stresses up to 200 MPa and fluid-saturated). Samples consisting of calcite, talc, chlorite and kaolinite (sample ZF01) and of calcite, tremolite, hornblende, kaolinite, chlorite and quartz (sample ZF02) were sheared at sliding velocities of 0.3-300 μm/s to displacements larger than 40 mm (i.e. γ > 40). Sample ZF01 was weaker than sample ZF02 at all conditions investigated. We attribute the lower strength to the weak talc present in this sample which is absent in sample ZF02. Both samples showed inherently stable, velocity-strengthening behaviour at room temperature, in

  20. The origin of radiogenic isotope variability in granites: intracrustal recycling and/or juvenile crust production?

    NASA Astrophysics Data System (ADS)

    Farina, Federico

    2014-05-01

    by the time evolved inherited zircon population, suggesting that the ɛHf heterogeneity of magmatic zircon is inherited from the source. The model proposed involves dissolution at the emplacement level of detrital zircons within small magma volumes and crystallization of new zircon from these magma domains, prior to complete hafnium isotopic homogenization. In the second case, the extreme mineral-scale initial Sr isotope variability characterizing the Elba Island granitic complex (Italy) is explained by mixing between magma batches produced by disequilibrium melting of individual crustal sources. These batches represent discrete melting events taking place as the isotherms advance through the source: the earlier magmas represent lower-temperature melts while magmas developed later formed at higher-temperature. The prime implication of these studies is that isotope variations in granitoids do not necessarily call for the involvement of a mantle-derived component. Substantial isotopic variation is to be expected in felsic magmas produced solely by reworking of crustal material, with no net crustal growth. Isotopic variability, generated during crustal anatexis, can survive magma segregation and ascent indicating the lack of pluton-wide homogenization occurring at the emplacement level.

  1. A little island with significant groundwater resources: hydrogeological and hydrogeochemical features of the Pianosa aquifer (Tuscan Archipelago, Italy)

    NASA Astrophysics Data System (ADS)

    Giannecchini, R.; Doveri, M.; Mussi, M.; Nicotra, I.; Puccinelli, A.

    2012-12-01

    below the sea level has been identified in the eastern part of the island. The electric conductivity (EC) map confirms this hydrogeological structure. EC values above 1.000 μS/cm are common in almost all the groundwater analyzed. An increase in groundwater salinity is observable in the eastern part of Pianosa, where the water table depression has been recognized. In agreement with the hydro-structural and water table conditions, the hydrogeochemical analyses confirm the recharge of the confined horizons (conglomerate and sandstone) by the superficial calcarenite. The isotopic data indicate that the aquifer system is recharged by the rainfall direct infiltration and there are not connections with the close Elba Island. Finally, the chemical analyses of most groundwater samples suggest an intermediate facies Na-Cl/Ca-HCO3, produced by the combination of the sea spray and the circulation in a prevalently carbonate aquifer (calcarenite). Clearly Na-Cl groundwater prevails in the eastern portion of the island, evidencing the seawater intrusion in the calcarenite, also confirmed by water table conditions and isotopic data.

  2. Effect of Dehydration Reaction on Serpentinite Deformation in Torsion

    NASA Astrophysics Data System (ADS)

    Vinciguerra, S.; Trovato, C.; Meredith, P. G.; Benson, P. M.; Hirose, T.; Bystricky, M.; Stünitz, H.; Kunze, K.

    2003-12-01

    Dehydration of serpentine to olivine, talc and water during deformation is critical for understanding the possible localization of deformation into shear zones and the generation of earthquakes along subduction zones. In order to investigate the effect of the dehydration reaction on the strength and ductility of serpentinite, torsion experiments were performed using a Paterson high PT torsion rig at constant shear strain rates of 10-4 to 10-5 s-1, temperatures of 550 to 750 ° C and a confining pressure of 300 MPa, to local shear strains up to γ = 3. We deformed two types of serpentinite: antigorite from Val Malenco, Italy, a high-temperature phase of serpentine (stable at T <500 ° C), and lizardite from Elba, Italy, a low-temperature phase of serpentine (stable at T <400 ° C). Most of the samples were shaped in dog-bone geometry with a central hole along their axial direction which acted as a fluid conduit, enabling an easy escape for any released fluid during the dehydration reaction. We also deformed solid bone-shaped specimens to compare the mechanical behavior of solid and hollow specimens. In both cases, porous alumina spacers were placed on both end sides of specimen and led to the atmosphere through the pore pressure line. Thus our experiments were performed under drained conditions. Antigorite deformed in the semi-brittle field at the run conditions. Visible faults formed probably due to reaction-induced fracturing, and the stress started to drop just after the initial peak stress ( ˜350 MPa at 650 to 700 ° C and ˜280 MPa at 750 ° C). Highly comminuted grains with various sizes along the faults were identified as partially dehydrated antigorite (H2O ˜6 wt%) at 650 ° C and olivine and talc at >700 ° C. Mechanical behavior after the peak stress is thought to occur by cataclastic flow, possibly assisted by diffusion mass transfer processes of these fine-grained reactant minerals. We have also investigated the effect of pre-heating on the strength of

  3. Frictional properties of Zuccale Fault rocks from room temperature to in-situ conditions: results from high strain rotary shear experiments

    NASA Astrophysics Data System (ADS)

    Niemeijer, A.; Collettini, C.; Smith, S. A. F.; Spiers, C. J.

    2012-04-01

    The Zuccale fault is a regionally-important, low-angle normal fault, exposed on the Isle of Elba in Central Italy, that accommodated a total shear displacement of 6-8 km.The fault zone structure and fault rocks formed at less than 8 km crustal depth. The present-day fault structure is the final product of several deformation processes superposed during the fault history. Here, we focus on a series of highly foliated and phyllosilicate-rich fault rocks that represent the basal horizon of the detachment. Previous experimental work on foliated, intact samples, sheared in their in-situ microstructural (foliated) condition, demonstrated a markedly lower friction coefficient compared to homogeneously mixed powdered samples of the same material. In this study, we report results from a series of rotary shear experiments performed on 1 mm thick powdered gouges made from several fault rock types obtained from the Zuccale Fault. The tests were done under conditions ranging from room temperature to in-situ conditions (i.e. at temperatures up to 300 °C, applied normal stresses up to 200 MPa and fluid-saturated.) The ratio of fluid pressure to effective normal stress was held constant at either λ=0.4 or λ=0.8 to simulate an over-pressurized fault. The samples were sheared at a constant sliding velocity of 10 μm/s for at least 5 mm, after which a velocity-stepping sequence from 1 to 300 μm/s was started to determine the velocity dependence of friction. This can be represented by the rate-and-state parameter (a-b), which was determined by an inversion of the data to the rate-and-state equations. Friction of the various fault rocks is between 0.3 and 0.7, similar to values obtained in a previous study, and decreases with increasing phyllosilicate content. Friction decreases mildly with temperature whereas normal stress and fluid pressure do not affect friction values systematically. All samples exhibited velocity-strengthening, inherently stable behavior under room temperature

  4. Using a landslide inventory from online news to evaluate the performance of warning models for rainfall-induced landslides in Italy

    NASA Astrophysics Data System (ADS)

    Pecoraro, Gaetano; Calvello, Michele

    2017-04-01

    In Italy rainfall-induced landslides pose a significant and widespread hazard, resulting in a large number of casualties and enormous economic damages. Mitigation of such a diffuse risk cannot be attained with structural measures only. With respect to the risk to life, early warning systems represent a viable and useful tool for landslide risk mitigation over wide areas. Inventories of rainfall-induced landslides are critical to support investigations of where and when landslides have happened and may occur in the future, i.e. to establish reliable correlations between rainfall characteristics and landslide occurrences. In this work a parametric study has been conducted to evaluate the performance of correlation models between rainfall and landslides over the Italian territory using the "FraneItalia" database, an inventory of landslides retrieved from online Italian journalistic news. The information reported for each record of this database always include: the site of occurrence of the landslides, the date of occurrence, the source of the news. Multiple landslides occurring in the same date, within the same province or region, are inventoried together in one single record of the database, in this case also reporting the number of landslides of the event. Each record the database may also include, if the related information is available: hour of occurrence; typology, volume and material of the landslide; activity phase; effects on people, structures, infrastructures, cars or other elements. The database currently contains six complete years of data (2010-2015), including more than 4000 landslide reports, most of them triggered by rainfall. For the aim of this study, different rainfall-landslides correlation models have been tested by analysing the reported landslides, within all the 144 zones identified by the national civil protection for weather-related warnings in Italy, in relation to satellite-based precipitations estimates from the Global Precipitation

  5. Studies on damage of D. suzukii on grapes cultivated in Apulia Region

    NASA Astrophysics Data System (ADS)

    Broutou, Oussama; Baser, Nuray; Porcelli, Francesco; Verrastro, Vincenzo; Lamaj, Flutura

    2014-05-01

    each sample and put in contact with adults of D. suzukii (5 males and 5 females) for 24 hours. Infestation percentages were expressed by numbers of eggs and infected berries per sample As a preliminary results, we found a relevant infestation on the varieties "Italia" (75%) and "Scarlotta" (60%); coming form organic agriculture fields. The number of eggs collected from each berry ranged from 1 to 5. Twelve samples on a total of 19 came from conventional agriculture, five samples on a total of 23 came from organic agriculture, were found without damages. "Victoria" variety, came form a organic field located at IAMB was seen more resistant to D. suzukii than the varieties "Italia" and "Scarlotta" As a conclusion, there is the evidence that D. suzukii can become a big problem for grape cultivation in Puglia region, jeopardizing a very economically important sector of the regional agriculture Therefore, it is necessary a further investigation to understand the population dynamic and behaviour of this species as well as the possible control strategies for a control in organic agriculture. Key words: Drosophila suzukii, Vitis vinifera, Puglia, infestation, damages, organic agriculture, conventional agriculture

  6. Gypsum karst in Italy: a review

    NASA Astrophysics Data System (ADS)

    De Waele, Jo; Chiarini, Veronica; Columbu, Andrea; D'Angeli, Ilenia M.; Madonia, Giuliana; Parise, Mario; Piccini, Leonardo; Vattano, Marco; Vigna, Bartolomeo; Zini, Luca; Forti, Paolo

    2016-04-01

    . Forti P., Lucci P. (Eds.) (2010) - Il Progetto Stella-Basino. Studio multidisciplinare di un sistema carsico nella Vena del Gesso Romagnola. Memorie Ist. It. Spel. II(14), 260 p. Lucci P., Piastra S. (Eds.) (2015), I Gessi di Brisighella e Rontana: studio multidisciplinare di un'area carsica nella Vena del Gesso Romagnola. Memorie Ist. It. Spel. II(28), 751 p. Madonia G., Forti P. (2003) - Le aree carsiche gessose d'Italia. Memorie Ist. It. Spel. II(14), 285 p. Madonia G., Vattano M. (2011) - New knowledge on the Monte Conca gypsum karst system (central-western Sicily, Italy). Acta Carsologica, 40, (1), pp. 53-64. Marinelli O. (1917) - Fenomeni carsici nelle regioni gessose d'Italia. Mem. Geografiche di Giotto Dainelli, 34, pp. 263-416, suppl. to Riv. Geografica It Tedeschi L. et al. (2015) - Comportamento idrogeologico di alcune risorgenti carsiche nei gessi dell'Emilia-Romagna. Memorie Ist. It. Spel. II(29), pp. 399-404. Vigna B. et al. (2010) - Evolution of karst in Messinian gypsum (Monferrato, Northern Italy). Geodinamica Acta, 23(1-3), pp. 29-40. Zini L. et al. (2015) - a multidisciplinary approach in sinkhole analysis: the Quinis village case study (NE-Italy). Engineering Geology, 197, pp.132-144.

  7. Biopsy of Different Oral Soft Tissues Lesions by KTP and Diode Laser: Histological Evaluation

    PubMed Central

    Romeo, Umberto; Russo, Claudia; Lo Giudice, Rossella; Visca, Paolo; Migliau, Guido

    2014-01-01

    Introduction. Oral biopsy aims to obtain clear and safe diagnosis; it can be performed by scalpel or laser. The controversy in this latter application is the thermal alteration due to tissue heating. The aim of this study is the histological evaluation of margins of “in vivo” biopsies collected by diode and KTP lasers. Material and Methods. 17 oral benign lesions biopsies were made by diode 808 nm (SOL, DenMatItalia, Italy) and KTP 532 nm (SmartLite, DEKA, Italy). Samples were observed at OM LEICA DM 2000; margin alterations were evaluated through Leica Application Suite 3.4. Results. Epithelial and connective damages were assessed for each pathology with an average of 0.245 mm and a standard deviation of ±0.162 mm in mucoceles, 0.382 mm ± 0.149 mm in fibromas, 0.336 mm ± 0.106 mm in hyperkeratosis, 0.473 mm ± 0.105 mm in squamous hyperplasia, 0.182 mm in giant cell granuloma, and 0.149 mm in melanotic macula. Discussion. The histologic aspect of lesions influenced the response to laser, whereas the greater inflammation and cellularity were linked with the higher thermal signs. Many artifacts were also associated to histologic procedures. Conclusion. Both tested lasers permitted sure histologic diagnosis. However, it is suggested to enlarge biopsies of about 0.5 mm, to avoid thermal alterations, especially in inflammatory lesions like oral lichen planus. PMID:25405233

  8. Mineral dust deposition in Western Mediterranean basin

    NASA Astrophysics Data System (ADS)

    Vincent, Julie; Laurent, Benoit; Bergmatti, Gilles; Losno, Rémi; Bon Nguyen, Elisabeth; Chevaillier, Servanne; Roulet, Pierre; Sauvage, Stéphane; Coddeville, Patrice; Ouboulmane, Noura; Siour, Guillaume; Tovar Sanchez, Antonio; Massanet, Ana; Morales Baquero, Rafael; Di Sarra, Giogio; Sferlazzo, Damiano; Dulac, François; Fornier, Michel; Coursier, Cyril

    2014-05-01

    North African deserts are the world's largest sources of atmospheric mineral dust produced by aeolian erosion. Saharan dust is frequently transported toward Europe over the Mediterranean basin. When deposited in oceanic areas, mineral dust can constitute a key input of nutrients bioavailable for the oceanic biosphere. For instance, Saharan dust deposited in the in the Mediterranean Sea can be a significant source of nutrient like Fe, P and N during summer and autumn. Our objective is to study the deposition Saharan mineral dust in the western Mediterranean basin and to improve how deposition processes are parameterized in 3D regional models. To quantify the deposition flux of Saharan dust in the western Mediterranean region a specific collector (CARAGA) to sample automatically the insoluble atmospheric particle deposition was developed (LISA-ICARE) and a network of CARAGA collectors have been set up. Since 2011, eight CARAGA are then deployed in Frioul, Casset, Montandon and Ersa in France, Mallorca and Granada in Spain, Lampedusa in Italia, and Medenine in Tunisia, along a South-North gradient of almost 2000km from the North African coast to the South of Europe. We observe 10 well identified dust Saharan deposition events at Lampedusa and 6 at Mallorca for a 1-yr sampling period. These dust events are sporadic and the South-North gradient of deposition intensity and frequency is observed (the highest dust mass sampled at the stations are : 2,66 g.m-2 at Lampedusa ; 0,54 g.m-2 at Majorque ; 0,33 g.m-2 at Frioul ; 0,16 g.m-2 at Casset). The ability of the CHIMERE model to reproduce the deposition measurements is tested. The mineral dust plumes simulated over the western Mediterranean basin are also compared to satellite observations (OMI, MODIS) and in-situ measurements performed during the ChArMEx campaign and in the AERONET stations.

  9. Chemical speciation and source apportionment of gaseous precursors observed at a remote site in the Mediterranean basin

    NASA Astrophysics Data System (ADS)

    Michoud, Vincent; Sauvage, Stéphane; Dusanter, Sébastien; Leonardis, Thierry; Locoge, Nadine

    2014-05-01

    Models of atmospheric chemistry suggest that aged anthropogenic air masses still contain significant levels of reactive trace gases such as mono- and multi-functional oxygenated volatile organic compounds, even after several days of oxidation. These air masses can significantly impact the oxidative capacity and the formation rate of secondary pollutants (ozone, SOA…) at remote locations. However, large uncertainties still remain about chemical processes occurring during long range transport that leads to the oxidation of anthropogenic pollutants. Long term measurements of volatile organic compounds and inorganic species are being conducted since July 2012 at a remote site in Cape Corsica, a receptor site experiencing events of long range transport of air masses from different urbanized areas (south of France, Spain, Italia, North of Africa). In addition to the long term monitoring, an extended suite of trace gases and aerosols was acquired as part of the 2013 ChArMEx field campaign at Cape Corsica. One of the objectives was to better understand chemical and physical processes occurring during long range transport of anthropogenic plumes. In this presentation, we will first apportion primary and secondary sources of VOCs observed at this remote site using an analysis of spatial and temporal variations of their concentrations, ratios of chemical tracers, and air mass trajectory clustering. We will then present the results from a concentration field approach. This statistical method, based on a large set of data, consists in redistributing the concentrations of selected VOCs to the trajectories in order to identify potential source areas influencing the receptor site. The results of these two approaches will provide relevant information to study chemical processes occurring in different types of plumes transported over the Mediterranean basin.

  10. The mineralogy and chemistry analyser (MARS-XRD) for the ExoMars 2018 mission

    NASA Astrophysics Data System (ADS)

    Marinangeli, L.; Hutchinson, I. B.; Stevoli, A.; Adami, G.; Ambrosi, R.; Amils, R.; Assis Fernandes, V.; Baliva, A.; Basilevsky, A. T.; Benedix, G.; Bland, P.; Böttger, A. J.; Bridges, J.; Caprarelli, G.; Cressey, G.; Critani, F.; D'Alessandro, N.; Delhez, R.; Domeneghetti, C.; Fernandez-Remolar, D.; Filippone, R.; Fioretti, A. M.; Garcia Ruiz, J. M.; Gilmore, M.; Hansford, G. M.; Iezzi, G.; Ingley, R.; Ivanov, M.; Marseguerra, G.; Moroz, L.; Pelliciari, C.; Petrinca, P.; Piluso, E.; Pompilio, L.; Sykes, J.; Westall, F.

    2011-10-01

    The Mineralogy and Chemistry Analyser (MARSXRD) is a miniaturised X-ray diffraction and fluorescence (XRD/XRF) spectrometer aimed to the mineralogical characterisation of Martian rocks. Simultaneously, MARS-XRD is able to acquire the diffraction pattern for mineralogical phases identification and the X-ray fluorescence spectrum for the chemical species, providing a complete rock characterization. The X-ray diffractometer (XRD) is the routine instrument used in every Earth Science laboratory to provide the mineralogical composition of rocks. XRD produces unequivocal results because it is based on the recognition of the geometrical properties of the crystal lattice. This kind of investigation is an extremely useful tool to define the textural and petro-mineralogical characteristics of the Martian rocks or soils and provide information on the past Martian environment conditions related to life. The analytic range we plan to cover includes all the silicate minerals, from clays or other phyllosilicates characterised by high interplanar lattice distance, to oxide and carbonates or evaporates (mainly sulphates). This rock spectrum is what we expect to be the target for exobiological exploration. These data will be integrated with those obtained by elemental analysis, in order to determine the exact elemental chemistry characterization of rock components. As mineralogy can be unambiguously derived from XRD analysis, it is probably our most powerful tool for distinguishing targets of biologic importance. In summary, the main scientific objectives of the proposed XRD/XRF instrument, Mars-XRD, are: - In situ determination of the mineral paragenesis of rock samples; - The characterization of the origin of rock samples; - Determination of alteration processes; - Understanding the exobiological potential of the samples. The hardware is developed by the Thales Alenia Space Italia with an important contribution of the Univ. of Leicester for the detection system.

  11. Evidence for mito-nuclear and sex-linked reproductive barriers between the hybrid Italian sparrow and its parent species.

    PubMed

    Trier, Cassandra N; Hermansen, Jo S; Sætre, Glenn-Peter; Bailey, Richard I

    2014-01-01

    Studies of reproductive isolation between homoploid hybrid species and their parent species have rarely been carried out. Here we investigate reproductive barriers between a recently recognized hybrid bird species, the Italian sparrow Passer italiae and its parent species, the house sparrow P. domesticus and Spanish sparrow P. hispaniolensis. Reproductive barriers can be difficult to study in hybrid species due to lack of geographical contact between taxa. However, the Italian sparrow lives parapatrically with the house sparrow and both sympatrically and parapatrically with the Spanish sparrow. Through whole-transcriptome sequencing of six individuals of each of the two parent species we identified a set of putatively parent species-diagnostic single nucleotide polymorphism (SNP) markers. After filtering for coverage, genotyping success (>97%) and multiple SNPs per gene, we retained 86 species-informative, genic, nuclear and mitochondrial SNP markers from 84 genes for analysis of 612 male individuals. We show that a disproportionately large number of sex-linked genes, as well as the mitochondria and nuclear genes with mitochondrial function, exhibit sharp clines at the boundaries between the hybrid and the parent species, suggesting a role for mito-nuclear and sex-linked incompatibilities in forming reproductive barriers. We suggest that genomic conflict via interactions between mitochondria and sex-linked genes with mitochondrial function ("mother's curse") at one boundary and centromeric drive at the other may best explain our findings. Hybrid speciation in the Italian sparrow may therefore be influenced by mechanisms similar to those involved in non-hybrid speciation, but with the formation of two geographically separated species boundaries instead of one. Spanish sparrow alleles at some loci have spread north to form reproductive barriers with house sparrows, while house sparrow alleles at different loci, including some on the same chromosome, have spread in

  12. [Waiting time between acute event and rehabilitation: continuity of nursing care and rehabilitation. Analysis and suggestions for a Service of Protected Discharge].

    PubMed

    D'Ilio, Ilaria; Raimondi, Anna Maria; Radice, Laura; Di Mauro, Stefania

    2014-01-01

    INTRODUZIONE. In Italia negli ultimi anni l’aumento della sopravvivenza della popolazione ha comportato il cambiamento dello stato di salute, che vede l’incremento nella prevalenza delle patologie croniche (Osservatorio, 2011). L’ospedale, riservato alla fase acuta delle patologie, si integra necessariamente con le cure primarie. La continuità assume particolare rilevanza per la cura, assistenza e riabilitazione della persona assistita, così come l’appropriato utilizzo delle diverse tipologie di offerta socio sanitaria assistenziale e riabilitativa. OBIETTIVO. Al San Gerardo di Monza, nell’ambito della riabilitazione del paziente post-acuto, si analizza la fase che intercorre tra la dimissione prevista dall’ospedale e la data di accettazione presso gli istituti di riabilitazione. E’ possibile quantificare i tempi di attesa? L’ allocazione delle persone assistite è appropriata? Scopo dello studio osservazionale descrittivo è accertare la distribuzione dei giorni di attesa. Inoltre si ipotizza il ricorso all’Assistenza Domiciliare Integrata e a soluzioni innovative. Obiettivi sono la diminuzione delle giornate di degenza inappropriate e l’utilizzo delle risorse in modo congruo. RISULTATI. Delle 1083 persone in attesa di riabilitazione il 55% (652), a cui sono associate 4505 giornate “inappropriate”, è stato dimesso dall’ospedale oltre i tempi previsti. CONCLUSIONI. L’utilizzo dell’assistenza domiciliare, vantaggiosa per l’ospedale, può essere utilizzata solo per una minoranza di pazienti e in modo diseconomico. Per abbattere la totalità delle giornate, una soluzione innovativa può essere l’istituzione di posti letto a basso costo. E dato che la maggioranza dei casi sono solo ad alta complessità assistenziale ma a bassa intensità clinica potrebbero essere letti gestiti da infermieri.

  13. The Mice Drawer System (MDS) experiment and the space endurance record-breaking mice.

    PubMed

    Cancedda, Ranieri; Liu, Yi; Ruggiu, Alessandra; Tavella, Sara; Biticchi, Roberta; Santucci, Daniela; Schwartz, Silvia; Ciparelli, Paolo; Falcetti, Giancarlo; Tenconi, Chiara; Cotronei, Vittorio; Pignataro, Salvatore

    2012-01-01

    The Italian Space Agency, in line with its scientific strategies and the National Utilization Plan for the International Space Station (ISS), contracted Thales Alenia Space Italia to design and build a spaceflight payload for rodent research on ISS: the Mice Drawer System (MDS). The payload, to be integrated inside the Space Shuttle middeck during transportation and inside the Express Rack in the ISS during experiment execution, was designed to function autonomously for more than 3 months and to involve crew only for maintenance activities. In its first mission, three wild type (Wt) and three transgenic male mice over-expressing pleiotrophin under the control of a bone-specific promoter (PTN-Tg) were housed in the MDS. At the time of launch, animals were 2-months old. MDS reached the ISS on board of Shuttle Discovery Flight 17A/STS-128 on August 28(th), 2009. MDS returned to Earth on November 27(th), 2009 with Shuttle Atlantis Flight ULF3/STS-129 after 91 days, performing the longest permanence of mice in space. Unfortunately, during the MDS mission, one PTN-Tg and two Wt mice died due to health status or payload-related reasons. The remaining mice showed a normal behavior throughout the experiment and appeared in excellent health conditions at landing. During the experiment, the mice health conditions and their water and food consumption were daily checked. Upon landing mice were sacrificed, blood parameters measured and tissues dissected for subsequent analysis. To obtain as much information as possible on microgravity-induced tissue modifications, we organized a Tissue Sharing Program: 20 research groups from 6 countries participated. In order to distinguish between possible effects of the MDS housing conditions and effects due to the near-zero gravity environment, a ground replica of the flight experiment was performed at the University of Genova. Control tissues were collected also from mice maintained on Earth in standard vivarium cages.

  14. [Effectiveness of school-based interventions to prevent traffic accidents: an overview of secondary literature].

    PubMed

    Guerriero, Chiara; Verdina, Federico; Ferri, Chiara; Pizzaguerra, Martina; Silvestri, Silvia; Tober, Nastassja; Ristagno, Quenya; Costa, Alessandro; Cerasuolo, Michele; Faggiano, Fabrizio; Allara, Elias

    2016-01-01

    INTRODUZIONE: gli incidenti stradali sono l'ottava causa di morte al mondo e la prima tra i giovani di 15-29 anni. In Italia il Piano nazionale sicurezza stradale raccomanda l'educazione scolastica per la prevenzione degli incidenti stradali; ad oggi non esistono documenti che raccolgano evidenze di efficacia sugli interventi educativi stradali e le rapportino al contesto italiano. OBIETTIVI: riassumere e discutere ciò che è noto in letteratura riguardo agli interventi scolastici per la prevenzione degli incidenti stradali. METODI: sono state ricercate linee guida e revisioni sistematiche usando i seguenti criteri di inclusione: popolazione di età inferiore ai 25 anni di entrambi i sessi; interventi scolastici di educazione stradale; effetti su indicatori primari di esito come riduzione degli incidenti stradali, astinenza dalla guida sotto l'effetto di alcol e dall'accettare passaggi in macchina da guidatori che sono sotto l'effetto di alcol; effetti su indicatori secondari di esito come conoscenze e competenze sui comportamenti di guida sicura. RISULTATI: sono state identificate due revisioni sistematiche. L'educazione stradale nelle scuole non mostra evidenza di efficacia (rischio relativo 1,03; IC95% 0,98-1,08) nel ridurre gli incidenti. Programmi scolastici più specifici mostrano risultati solo in parte convincenti per l'adozione di comportamenti sicuri come l'astinenza dal guidare sotto l'effetto di alcol e dall'accettare passaggi in macchina da guidatori che sono sotto l'effetto di alcol. DISCUSSIONE: le revisioni incluse non hanno trovato programmi efficaci nella riduzione degli incidenti stradali o dei fattori che possano determinarli. Nell'attesa di studi più recenti, appare opportuno promuovere l'implementazione di interventi misti, scolastici e di comunità, che hanno mostrato maggiori prove di efficacia.

  15. [Valutazione del carico gestionale in un centro diurno psichiatrico: gravosità e recovery style].

    PubMed

    Callegari, Camilla; Caselli, Ivano; Bertù, Lorenza; Berto, Emanuela; Vender, Simone

    2016-01-01

    RIASSUNTO. Scopo. Nella riabilitazione psichiatrica il piano di trattamento individuale può essere formulato a partire da strumenti che offrano una valutazione multidimensionale del paziente. Il lavoro si propone di analizzare il rapporto tra gravosità (distress degli operatori) e stile di recupero (integration e sealing over) dalla patologia psicotica. Ipotizzando che esso influenzi il carico gestionale, lo studio si pone l'ulteriore obiettivo di acquisire maggiori elementi che indirizzino la formulazione di piani terapeutico-riabilitativi più efficaci. Metodi. Lo studio è stato condotto presso un centro diurno psichiatrico, struttura semi-residenziale dei servizi psichiatrici del Sistema Sanitario Nazionale in Italia. 45 pazienti reclutati sono stati valutati mediante la Neuropsychiatric Inventory (NPI - versione italiana) e la Integration/Sealing Over Scale (ISOS - versione italiana), nell'arco di tre mesi (marzo-giugno 2014). Risultati. Nel campione esaminato è emerso che la disinibizione, l'irritabilità e l'apatia sono i sintomi che provocano maggiore distress negli operatori, in senso assoluto. Inoltre, i risultati indicano che depressione e ansia recano un grado maggiore di distress nei pazienti sealer. Discussione e conclusione. Gli aspetti della disinibizione, dell'irritabilità e dell'apatia sono risultati più gravosi per gli operatori in quanto richiedono maggiore coinvolgimento nella relazione terapeutica. Sintomi ansiosi e depressivi risultano più gravosi nel gruppo dei sealer, segnalando minore tenuta della negazione della psicosi. I dati osservati sembrano provare che conoscere, differenziare e approfondire i diversi aspetti dello stile di recupero di ciascun paziente consente di stimare l'impegno gestionale fin dalla presa in carico e di ridurre il distress e il rischio di burnout degli operatori.

  16. Validation of the Italian Version of the Morningness-Eveningness Questionnaire for Adolescents by A. Lancry and Th. Arbault

    PubMed Central

    Cavallera, Guido M.; Boari, Giuseppe

    2015-01-01

    Background This study aimed to validate the Italian version of the Morningness-Eveningness questionnaire for adolescents by Lancry and Arbault. Material/Methods The Morningness-Eveningness Questionnaire by Lancry and Arbault was translated from French into Italian by using forward-backward translation. Students aged 11–15 years old were enrolled from two schools in Milan (Italia). Validation of the questionnaire was performed in subsequent phases. A pre-test was given to 66 students aged 11–15 years (males 57.4%, females 42.6%) from a convenience sample. Syntactic aspects of the pre-test were improved, and the questionnaire in a revised version was re-administered to 292 students of same age (males 43.8%, females 54.1%) from a convenience sample. Results Factor analysis was performed on pre-test data, using the principal component method accounting for Morningness-Eveningness. Problematic items possibly uncorrelated with the extracted factor were identified, and reliability produced a Cronbach’s Alpha close to 0.7. In the test phase factor analysis was performed using the principal component method. Based on reliability analyses, we excluded a number of items because of their low performance, giving rise to a Cronbach’s Alpha of 0.819. Pearson product-moment external correlations between Morningness-Eveningness disposition and temperament, behavioral, and cognitive aspects were evaluated. Conclusions A factor analysis, Cronbach’s alpha and concurrent validity coefficients with disposition, behavior, and cognition, were performed, suggesting potential reliability and validity. The questionnaire is a useful and relevant tool for measuring Morningness-Eveningness disposition in adolescents, which has seldom been investigated with adequate psychometric instruments. PMID:26354147

  17. Ethnobotanical notes about some uses of medicinal plants in Alto Tirreno Cosentino area (Calabria, Southern Italy)

    PubMed Central

    Leporatti, Maria Lucia; Impieri, Massimo

    2007-01-01

    Background The present paper contributes to enrich the ethnobotanical knowledge of Calabria region (Southern Italy). Research was carried out in Alto Tirreno Cosentino, a small area lying between the Tyrrhenian coast and the Pollino National Park. In the area studied medicinal plants still play a small role among farmers, shepherds and other people who live far from villages and built-up areas. Methods Information was collected by interviewing native people, mainly elderly – engaged in farming and stock-raising activities – and housewives. The plants collected, indicated by the locals, have been identified according to "Flora d'Italia". The exsiccata vouchers are preserved in the authors' own herbaria. Results 52 medicinal species belonging to 35 families are listed in this article. The family, botanical and vernacular name, part of the plant used and respective manipulation are reported there and, when present, similar or identical uses in different parts of Calabria or other Italian regions are also indicated. Conclusion Labiatae, Rosaceae and Leguminosae are the families most frequently present, whilst Compositae and Brassicaceae are almost absent. The uses of the recorded species relate to minor ailments, mainly those of the skin (15 species), respiratory apparatus diseases (11), toothache, decay etc. (10) and rheumatic pains (8). The easy availability of these remedies provides a quick way of curing various minor complaints such as tooth-ache, belly and rheumatic pain and headaches and can also serve as first aid as cicatrizing, lenitive, haemostatic agents etc. The role in veterinary medicine is, on the contrary, more important: sores, ulcers, tinea, dermatitis, gangrenous wounds of cattle, and even respiratory ailments are usually cured by resort to plants. PMID:17983476

  18. National Workshop on Astrobiology: the life science involvement of AAS-I Laben.

    PubMed

    Adami, Giorgio

    2006-12-01

    The search for traces of past and present life is a complex and multidisciplinary research activity involving several scientific heritages and a specific industrial ability for planetary exploration. Laben was established in 1958 to design and manufacture electronic instruments for research in nuclear physics. In the mid 2004 the company was merged with Alenia Spazio. It is now part of Alcatel Alenia Space, a French Italian joint venture. Alcatel Alenia Space Italia SpA is a Finmeccanica Company. Currently the plant of Vimodrone provides a wide heritage in life science oriented to space application. The experience in Space Life Science is consolidated in the following research areas: (1) Physiology: Mouse models related to studies on human physiology Human neuroscience research and dosimetry (2) Animal Adaptation and Behaviour: mice behaviour related to stabling stress (3) Developmental Biology: aquatic microorganisms cultivation (4) Cell culture & Biotechnology: Protein crystal growth General purpose Multiwell Next Biotechnology studies and development: Bio reactor, mainly oriented to tissue engineering Microsensor for tissue control (organ replacement) Multiwell for adherent cell culture or for automated biosensor based on cell culture Experiment Container for organic systems Experiment Container for small animals Instrumentation based on fluorescent Biosensors Sensors for Life science experiments for Biopan capsule and Space Vehicle Ray Shielding Materials Random Positioning Machine specialisation (Support ground equipment) The biological features of this heritage is at disposal for the exobiology multi science. The involvement of industries, from the beginning of the exobiology projects, allows a cost effective technologies closed loop development between Research Centres, Principal Investigators and industry.

  19. 3d Operational Hydrodinamic Modelling System as a Support to Oil Spill Responses in the Ligurian Sea (North-Western Mediterranean)

    NASA Astrophysics Data System (ADS)

    Del Giudice, T.; Quagliati, M.; Bertolotto, R.; Pedroncini, A.; Cusati, L. A.

    2014-12-01

    Accidental oil spills have a significant impact on marine ecosystems reminding us the importance of an efficiency emergency planning to ensure a quick and proper response. In this phase, the numerical modelling approach emerges as a useful tool in order to simulate the scenarios and addresses the issue of oil dispersion in the case of a spill. The 3D operational hydrodynamic modelling system of the Ligurian Sea (North-Western Mediterranean) is used as a base to predict the possible oil trajectory and to track the path and fate of spilled oil under the prevailing hydrodynamic and meteorological conditions. The operative chain of the hydrodynamic model was developed by DHI Italia for the Regional Environment Protection Agency (ARPAL) operating in the Ligurian region (Italy) with the objective to preserve the environment, support the activities of the Civil Protection Department and promote a sustainable, healthy and safety management of the local resources. In this chain the MFS Mediterranean 3D model (operated within MyOcean EU Project - Copernicus Programme) was downscaled from 6.5 km to finer nearshore mesh (500 m). The increased spatial resolution allows the correct simulation of current developments in the vicinity of morphological discontinuities such as the promontory of Portofino on the Ligurian coast. The meteorological forcing is provided by MOLOCH, a LAM model operated by ARPAL together with fresh water discharges from the main rivers through hydrological modelling. Since the Ligurian Sea recently hosted the transfer of wreck Costa Concordia some real time simulations of hypothetical oil spill were performed to support the crisis unit of the Genoa Coast Guard. Simulations led to interesting results concerning the importance of updated weather conditions, which strongly influence current trends, focusing on the importance of the continuity of the modelling chain.

  20. Long-term trends in first arrival and first egg laying dates of some migrant and resident bird species in northern Italy

    NASA Astrophysics Data System (ADS)

    Rubolini, Diego; Ambrosini, Roberto; Caffi, Mario; Brichetti, Pierandrea; Armiraglio, Stefano; Saino, Nicola

    2007-08-01

    Climate change is affecting the phenology of seasonal events in Europe and the Northern Hemisphere, as shown by several studies of birds’ timing of migration and reproduction. Here, we analyse the long-term (1982-2006) trends of first arrival dates of four long-distance migratory birds [swift ( Apus apus), nightingale ( Luscinia megarhynchos), barn swallow ( Hirundo rustica), and house martin ( Delichon urbicum)] and first egg laying dates of two migrant (swift, barn swallow) and two resident species [starling ( Sturnus vulgaris), Italian sparrow ( Passer italiae)] at a study site in northern Italy. We also addressed the effects of local weather (temperature and precipitation) and a climate index (the North Atlantic Oscillation, NAO) on the interannual variability of phenological events. We found that the swift and the barn swallow significantly advanced both arrival and laying dates, whereas all other species did not show any significant temporal trend in either arrival or laying date. The earlier arrival of swifts was explained by increasing local temperatures in April, whereas this was not the case for arrival dates of swallows and first egg laying dates of both species. In addition, arrival dates of house martins were earlier following high NAO winters, while nightingale arrival was earlier when local spring rainfall was greater. Finally, Italian sparrow onset of reproduction was anticipated by greater spring rainfall, but delayed by high spring NAO anomalies, and swift’s onset of reproduction was anticipated by abundant rainfall prior to reproduction. There were no significant temporal trends in the interval between onset of laying and arrival in either the swift or the barn swallow. Our findings therefore indicate that birds may show idiosyncratic responses to climate variability at different spatial scales, though some species may be adjusting their calendar to rapidly changing climatic conditions.

  1. The past, present and future of B IOPAN

    NASA Astrophysics Data System (ADS)

    Demets, R.; Schulte, W.; Baglioni, P.

    B IOPAN is an exposure facility for biological experiments in space. Between 1992 and 1999 B IOPAN completed four missions in low Earth orbit on Russian F OTON satellites, whereby 16 experiments were conducted by Baglioni and Demets [Baglioni, P., Demets, R. Astrobiology on recoverable carriers: the ESA B IOPAN experience, in: 51th International Astronautical Congress, Rio de Janeiro, Brazil, 2-6 October 2000, IAF/IAA-00-4.2.02, 2000.] . A fifth attempt to put B IOPAN in orbit failed in 2002 when the launcher crashed. The B IOPAN programme will be resumed with two more flights in 2005 and 2006. B IOPAN is a pan-shaped container, fitted onto the outside of the F OTON spacecraft, carrying experiments with a total mass of 3.5 kg. By opening a motor-driven lid, the experiments are exposed to solar light, cosmic rays, vacuum and wide temperature fluctuations. The space environment is monitored by solar sensors, thermometers and investigator-provided radiation detectors. During re-entry, the lid is closed to prevent overheating of the experiments. The orbital parameters selected for the B IOPAN missions are highly consistent. This facilitates a repetition of the experiments if necessary, and it helps to predict the experiment environment on future flights. Over the years the capabilities of B IOPAN have gradually been enhanced. More, heavier and more complex experiments can now be accommodated, the sensors have been upgraded, power can be provided to the experiments and experiment data can be recorded. B IOPAN is designed and manufactured under ESA contract by Kayser-Threde (Germany) with Kayser Italia (Italy) and TsSKB-Progress (Russia) as subcontractors. This article focuses on the characteristics of B IOPAN as a tool for investigators. Information about the experiments and the scientific results can be found elsewhere.

  2. The impact of a simulated grand tour on sleep, mood, and well-being of competitive cyclists.

    PubMed

    Lastella, M; Roach, G D; Halson, S L; Martin, D T; West, N P; Sargent, C

    2015-12-01

    Professional cycling is considered one of the most demanding of all endurance sports. The three major professional cycling stages races (i.e. Tour de France, Giro d'Italia and Vuelta a España) require cyclists to compete daily covering between ~150-200 km for three consecutive weeks. Anecdotal evidence indicates that such an event has a significant effect on the sleep, mood, and general well-being of cyclists, particularly during the latter stages of the event. The primary aim of this study was to simulate a grand tour and determine the impact a grand tour has on the sleep, mood, and general well-being of competitive cyclists. Twenty-one male cyclists (M±SD, age 22.2±2.7 years) were examined for 39 days across three phases (i.e. baseline, simulated grand tour, and recovery). Sleep was assessed using sleep diaries and wrist activity monitors. Mood and general well-being were assessed using the Brunel Mood Scale (BRUMS) and Visual Analogue Scales (VAS). The amount and quality of sleep as assessed by the wrist activity monitors declined during the simulated grand tour. In contrast, self-reported sleep quality improved throughout the study. Cyclists' mood and general well-being as indicated by vigour, motivation, physical and mental state declined during the simulated tour. Future investigations should examine sleep, mood and well-being during an actual grand tour. Such data could prove instrumental toward understanding the sleep and psychological changes that occur during a grand tour.

  3. Non-susceptible landslide areas in Italy and in the Mediterranean region

    NASA Astrophysics Data System (ADS)

    Marchesini, I.; Ardizzone, F.; Alvioli, M.; Rossi, M.; Guzzetti, F.

    2014-04-01

    We used landslide information for 13 study areas in Italy and morphometric information obtained from the 3 arc-second SRTM DEM to determine areas where landslide susceptibility is expected to be null or negligible in Italy, and in the landmasses surrounding the Mediterranean Sea. The morphometric information consisted in the local terrain slope computed in a square 3 × 3 cell moving window, and in the regional relative relief computed in a circular 15 × 15 cell moving window. We tested three different models to determine the non-susceptible landslide areas, including a linear model (LR), a quantile linear model (QLR), and a quantile non-linear model (QNL). We tested the performance of the three models using independent landslide information represented by the Italian Landslide Inventory (Inventario Fenomeni Franosi in Italia - IFFI). Best results were obtained using the QNL model. The corresponding zonation of non-susceptible landslide areas was intersected in a GIS with geographical census data for Italy. The result allowed determining that 57.5% of the population of Italy (in 2001) was located in areas where landslide susceptibility is expected to be null or negligible, and that the remaining 42.5% was located in areas where some landslide susceptibility is expected. We applied the QNL model to the landmasses surrounding the Mediterranean Sea, and we tested the synoptic non-susceptibility zonation using independent landslide information for three study areas in Spain. Results proved that the QNL model was capable of determining where landslide susceptibility is expected to be negligible in the Mediterranean area. We expect our results to be applicable in similar study areas, facilitating the identification of non-susceptible and susceptible landslide areas, at the synoptic scale.

  4. Non-susceptible landslide areas in Italy and in the Mediterranean region

    NASA Astrophysics Data System (ADS)

    Marchesini, I.; Ardizzone, F.; Alvioli, M.; Rossi, M.; Guzzetti, F.

    2014-08-01

    We used landslide information for 13 study areas in Italy and morphometric information obtained from the 3-arcseconds shuttle radar topography mission digital elevation model (SRTM DEM) to determine areas where landslide susceptibility is expected to be negligible in Italy and in the landmasses surrounding the Mediterranean Sea. The morphometric information consisted of the local terrain slope which was computed in a square 3 × 3-cell moving window, and in the regional relative relief computed in a circular 15 × 15-cell moving window. We tested three different models to classify the "non-susceptible" landslide areas, including a linear model (LNR), a quantile linear model (QLR), and a quantile, non-linear model (QNL). We tested the performance of the three models using independent landslide information presented by the Italian Landslide Inventory (Inventario Fenomeni Franosi in Italia - IFFI). Best results were obtained using the QNL model. The corresponding zonation of non-susceptible landslide areas was intersected in a geographic information system (GIS) with geographical census data for Italy. The result determined that 57.5% of the population of Italy (in 2001) was located in areas where landslide susceptibility is expected to be negligible. We applied the QNL model to the landmasses surrounding the Mediterranean Sea, and we tested the synoptic non-susceptibility zonation using independent landslide information for three study areas in Spain. Results showed that the QNL model was capable of determining where landslide susceptibility is expected to be negligible in the validation areas in Spain. We expect our results to be applicable in similar study areas, facilitating the identification of non-susceptible landslide areas, at the synoptic scale.

  5. Emamectin benzoate: new insecticide against Helicoverpa armigera.

    PubMed

    Fanigliulo, A; Sacchetti, M

    2008-01-01

    Emamectin benzoate is a new insecticide of Syngenta Crop Protection, with a new mechanism of action and a strong activity against Lepidoptera as well as with and a high selectivity on useful organisms. This molecule acts if swallowed and has some contact action. It penetrates leaf tissues (translaminar activity) and forms a reservoir within the leaf. The mechanism of action is unique in the panorama of insecticides. In facts, it inhibits muscle contraction, causing a continuous flow of chlorine ions in the GABA and H-Glutamate receptor sites. During 2006 and 2007, experimentation was performed by the Bioagritest test facility, according to EPPO guidelines and Principles of Good Experimental Practice (GEP), aiming at establishing the biological efficacy and the selectivity of Emamectin benzoate on industry tomato against Helicoverpa armigera (Lepidoptera: Noctuidoe). The study was performed in Tursi-Policoro (Matera), southern Italy. Experimental design consisted in random blocks, in 4 repetitions. A dosage of 1.5 Kg/ha of the formulate was compared with two commercial formulates: Spinosad 0.2 kg/ha (Laser, Dow Agrosciences Italia) and Indoxacarb 0.125 kg/ha (Steward EC insecticide, Dupont). Three foliage applications were applied every 8 days. The severity of damage induced by H. armigera was evaluated on fruits. Eventual phytotoxic effects were also evaluated. Climatic conditions were optimal for Lepidoptera development, so that the percentage of fruits attacked in 2007 at the first scouting was 68.28%. Emamectin benzoate has shown, in two years of testing, a high control of H. armigera if compared with the standards Indoxacarb and Spinosad. No effect of phytotoxicity was noticed on fruits.

  6. Effects of 6 Single-File Systems on Dentinal Crack Formation.

    PubMed

    Pedullà, Eugenio; Genovesi, Francesco; Rapisarda, Silvia; La Rosa, Giusy R M; Grande, Nicola M; Plotino, Gianluca; Adorno, Carlos G

    2017-03-01

    The purpose of this study was to compare the formation of microcracks after canal preparation performed with different single-file systems as One Shape (Micro-Mega, Besancon, Cedex, France), F6 SkyTaper (Komet Italia Srl, Milan, Italy), HyFlex EDM (Coltene/Whaledent AG, Altstatten, Switzerland), WaveOne (Dentsply Maillefer, Ballaigues, Switzerland), Reciproc (VDW, Munich, Germany), and WaveOne Gold (Dentsply Maillefer). Eighty-four human extracted mandibular central incisors (40-60 y) were selected and divided into 6 experimental groups (n = 12 teeth) and a control group (unprepared teeth): One Shape (group 1), F6 SkyTaper (group 2), HyFlex EDM (group 3), WaveOne (group 4), Reciproc (group 5), and WaveOne Gold (group 6). Roots were then sectioned at 3, 6, and 9 mm from the apex, and the surface was observed under a stereomicroscope. Data were analyzed using logistic regression (P < .05). No cracks were observed in the control group. All the systems tested caused cracks, mainly in the apical section (3 mm). HyFlex EDM (33.3%) and WaveOne Gold (58.3%) showed fewer microcracks than other experimental groups (P < .01); however, no significant difference was found between them in crack formation (P > .05). There was no difference among the other experimental groups (P > .05). All the instruments tested created dentinal cracks. Within the limitations of this study, the flexibility of nickel-titanium instruments because of heat treatment seems to have a significant influence on dentinal crack formation. HyFlex EDM and WaveOne Gold caused less microcracks than the other instruments tested. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  7. Evidence for Mito-Nuclear and Sex-Linked Reproductive Barriers between the Hybrid Italian Sparrow and Its Parent Species

    PubMed Central

    Sætre, Glenn-Peter; Bailey, Richard I.

    2014-01-01

    Studies of reproductive isolation between homoploid hybrid species and their parent species have rarely been carried out. Here we investigate reproductive barriers between a recently recognized hybrid bird species, the Italian sparrow Passer italiae and its parent species, the house sparrow P. domesticus and Spanish sparrow P. hispaniolensis. Reproductive barriers can be difficult to study in hybrid species due to lack of geographical contact between taxa. However, the Italian sparrow lives parapatrically with the house sparrow and both sympatrically and parapatrically with the Spanish sparrow. Through whole-transcriptome sequencing of six individuals of each of the two parent species we identified a set of putatively parent species-diagnostic single nucleotide polymorphism (SNP) markers. After filtering for coverage, genotyping success (>97%) and multiple SNPs per gene, we retained 86 species-informative, genic, nuclear and mitochondrial SNP markers from 84 genes for analysis of 612 male individuals. We show that a disproportionately large number of sex-linked genes, as well as the mitochondria and nuclear genes with mitochondrial function, exhibit sharp clines at the boundaries between the hybrid and the parent species, suggesting a role for mito-nuclear and sex-linked incompatibilities in forming reproductive barriers. We suggest that genomic conflict via interactions between mitochondria and sex-linked genes with mitochondrial function (“mother's curse”) at one boundary and centromeric drive at the other may best explain our findings. Hybrid speciation in the Italian sparrow may therefore be influenced by mechanisms similar to those involved in non-hybrid speciation, but with the formation of two geographically separated species boundaries instead of one. Spanish sparrow alleles at some loci have spread north to form reproductive barriers with house sparrows, while house sparrow alleles at different loci, including some on the same chromosome, have spread

  8. Relationship between genotypes of the Duffy blood groups and malarial infection in different ethnic groups of Choco, Colombia

    PubMed Central

    Vega, Jorge; Ramirez, Jose L; Bedoya, Gabriel; Carmona-Fonseca, Jaime; Maestre, Amanda

    2012-01-01

    Introduction: The negative homozygous condition for the Duffy blood group (Fy-/Fy-) confers natural resistance to Plasmodium vivax infection. Studies carried out in pursuing this direction in Colombia are scarce. Objective: To describe the relationship between Duffy genotypes in three ethnic communities of La Italia (Chocó) and malarial infection. Methods: This is a descriptive, cross-sectional study in symptomatic and asymptomatic subjects with malaria. Sample size: Afro-Colombians 73; Amerindian (Emberá) 74, and Mestizo, 171. The presence of Plasmodium infection was assessed by thick smear and the status of the Duffy gene was studied by PCR and RFLP to help identify changes to T-46C and A131G which originate the genotypes T/T, T/C , C/C and G/G, G/A, A/A. Results: Infection by Plasmodium was detected in 17% of cases with 62% due to P. falciparum and 27% due to P. vivax. Duffy genotypes were significantly associated with ethnicity (p= 0.003). Individuals with the C/C, A/A diplotypes were exclusively infected by P. falciparum, whereas the other diplotypes were infected with either of the species. In the Amerindian and Mestizo populations, the frequency of the T-46 allele was 0.90-1.00, among Afro-Colombians this was 0.50, the same as with the C allele and with an absence of heterozygous. At locus 131, the maximum frequency of the G allele was 0.30 in Amerindians and the maximum of the A allele was 0.69 in Afro-Colombians. Conclusions: In the Amerindian and mestizo populations studied, there was a predominance of the allele T-46 (FY+) but this was not observed with the P. vivax infection. P. vivax was ruled out in all FY- individuals. PMID:24893190

  9. The FLECS expandable module concept for future space missions and an overall description on the material validation

    NASA Astrophysics Data System (ADS)

    Mileti, Sandro; Guarrera, Giuseppe; Marchetti, Mario; Ferrari, Giorgio; Nebiolo, Marco; Augello, Gerlando; Bitetti, Grazia; Carnà, Emiliano; Marranzini, Andrea; Mazza, Fabio

    2006-07-01

    The future space exploration missions aim to reduce the costs associated with design, fabrication and launch for ISS, Moon and Mars modules, while simultaneously increasing the useful volume. Flexible and inflatable structures offer many advantages over conventional structures for space applications. Principal among the advantages is the ability to package these structures into small volumes for launch. Design maturation and the development of advanced materials and fabrication processes have made the concept of an inflatable module achievable in the near future. The Multipurpose Expandable Module (FLECS) Project sponsored by ASI (Italian Space Agency) whose prime contractor is Alcatel Alenia Space Italia, links the conventional and traditional technology of modules with the innovative solutions of inflatable technology. This project emphasizes on demonstrating the capability in using inflatable technology on space structures aiming to substitute the conventional modules in future manned missions. FLECS has been designed using advanced textiles and films in order to guarantee the structural reliability necessary for the deployment and packaging configurations. A non-linear structural analysis has been conducted using several numerical codes that simulate the deployed structural characteristics achieving also the damping resistance during the packaging. All the materials used for the flexible parts have been selected through a series of mechanical tests in order to validate the more appropriate ones for the mission. The multi-layer pneumatic retention bladder and the intermediate restraint layer are composed of polymer sheets, ortho-fabrics and elastomers like polyurethanes. The External protection shield is configured using several layers of impact absorption materials and also several layers of space environment (UV, IR, atomic oxygen) protection materials such as Kapton, Mylar and Nextel. The validation of the fabrics, the films and the final prototype assembly

  10. Anidulafungin: ECB, LY 303366, V-echinocandin, VEC, VER 002, VER-02.

    PubMed

    2003-01-01

    Vicuron Pharmaceuticals (formerly Versicor Inc.) is developing anidulafungin [LY 303366, ECB, V-echinocandin, VEC, VER-02, VER 002], a lipopeptide echinocandin B derivative, for IV treatment of mycoses. Anidulafungin acts against fungal infection by inhibiting beta-1,3-glucan synthase, an enzyme essential for cell wall formation. Anidulafungin was originally developed for oral use by Eli Lilly and was undergoing phase II clinical trials in the UK and the US for the treatment of Candida, Aspergillus and Pneumocystis carinii infections. However, Eli Lilly discontinued development of the oral formulation due to poor oral bioavailability. In May 1999, Versicor obtained exclusive worldwide commercialisation rights to anidulafungin with responsibility for its development and clinical registration. Under the terms of the agreement, Eli Lilly received a signing fee, and will receive milestone payments upon future development of anidulafungin and royalties on future sales. Eli Lilly also retains an option for the development of an oral formulation of the compound. On 3 March 2003, Versicor Inc. of Fremont (California, USA) and Biosearch Italia SpA of Milan (Italy) announced the completion of a merger agreement, whereby Biosearch was merged with and into Versicor in a stock-for-stock exchange valued at US dollars 260.7 million. The combined company temporarily kept the name Versicor until the new name, Vicuron Pharmaceuticals, was announced on 26 March 2003. In January 2003, Versicor announced that positive results from a phase II trial for anidulafungin IV treatment involving 120 patients in the US with invasive candidiasis/candidaemia, have led to another double-blind, randomised phase III trial being conducted in the US, Canada and Europe for this indication. This additional phase III trial will enrol approximately 300 patients to investigate the efficacy of IV anidulafungin (200 mg loading dose followed by 100 mg maintenance dose) versus IV fluconazole for 10 to 42 days

  11. Monitoring Mediterranean marine pollution using remote sensing and hydrodynamic modelling

    NASA Astrophysics Data System (ADS)

    La Loggia, Goffredo; Capodici, Fulvio; Ciraolo, Giuseppe; Drago, Aldo; Maltese, Antonino

    2011-11-01

    Human activities contaminate both coastal areas and open seas, even though impacts are different in terms of pollutants, ecosystems and recovery time. In particular, Mediterranean offshore pollution is mainly related to maritime transport of oil, accounting for 25% of the global maritime traffic and, during the last 25 years, for nearly 7% of the world oil accidents, thus causing serious biological impacts on both open sea and coastal zone habitats. This paper provides a general review of maritime pollution monitoring using integrated approaches of remote sensing and hydrodynamic modeling; focusing on the main results of the MAPRES (Marine pollution monitoring and detection by aerial surveillance and satellite images) research project on the synergistic use of remote sensing, forecasting, cleanup measures and environmental consequences. The paper also investigates techniques of oil spill detection using SAR images, presenting the first results of "Monitoring of marine pollution due to oil slick", a COSMO-SkyMed funded research project where X-band SAR constellation images provided by the Italian Space Agency are used. Finally, the prospect of using real time observations of marine surface conditions is presented through CALYPSO project (CALYPSO-HF Radar Monitoring System and Response against Marine Oil Spills in the Malta Channel), partly financed by the EU under the Operational Programme Italia-Malta 2007-2013. The project concerns the setting up of a permanent and fully operational HF radar observing system, capable of recording surface currents (in real-time with hourly updates) in the stretch of sea between Malta and Sicily. A combined use of collected data and numerical models, aims to optimize intervention and response in the case of marine oil spills.

  12. Analysis of DSGSD using the DInSAR technique and geomorphological studies in central Italy

    NASA Astrophysics Data System (ADS)

    Tolomei, C.; Taramelli, A.; Moro, M.; Saroli, M.; Salvi, S.

    2008-12-01

    Considerable enhancement for morphometric interpretation can be obtained through generation of a synthetic stereo pair, by means of the integration of detailed photogeological analysis (Volo Italia 1987-1988) dataset, supported by SPOT images, 20m pixel-size Digital Elevation Model (DEM) and in situ observations. In this research we analyze the overall requirement and use of parameters derived from geomorphic analysis in synergy with DInSAR technique for Deep Seated Gravitational Slope Deformation (DSGSD) topography characterization in the Italy Central Apennine (Umbria-Marche area). The topographic approach employed to derive these insights is not intended for use in site-specific analyses of DSGSD potential but instead identify slopes whose morphology is indicative of deep seated phenomena. Geomorphological evidences from aerial photos and field observations shows large scale gravity driven phenomena (landslides, sackung or rock-flow, lateral spread and block slide), responsible for the landscape evolution of the whole area. The InSAR technique has been applied in order to understand the temporal behaviour and spatial distribution of such deformation. The interferograms show various isolated fringe patterns corresponding to some of the large scale gravitative phenomena previously and indipendently identified through geomorphic analysis. The final results indicate that when incorporated with the DInSAR technique the morphological analysis is useful to supervise the activity of identified DSGSDs in specific landscapes and quantify their surface movement. This research has promoted a structured and integrated approach to DSGSD assessment primarily from a quantitative perspective. The approach can have further positive implications. The application of the suggested methodology to areas characterized by the presence of different DSGSD typology and related to a seismic sequence could also allow to better separate tectonic and gravity contributions from the whole

  13. Meningococco B: controllo di due focolai epidemici mediante vaccinazione

    PubMed Central

    2014-01-01

    Riassunto La problematica di un efficace approccio vaccinale nei confronti del Meningococco B (MenB) è stata superata identificando con la metodica della "reverse vaccinology" alcuni antigeni capaci di indurre una risposta verso la maggior parte dei ceppi di MenB circolanti nel mondo. Il nuovo vaccino MenB a 4 componenti (4CMenB) è stato autorizzato in Europa, Australia e Canada, ed è entrato nei calendari di immunizzazione pediatrica internazionali: Australia, Canada, UK. In Italia, le prime regioni che hanno raccomandato la vaccinazione contro il MenB sono state Basilicata e Puglia. La gestione di epidemie/focolai epidemici richiede la messa in atto di una risposta rapida da parte delle autorità sanitarie nei confronti di una emergenza sanitaria ad elevato impatto, anche emotivo, sulla popolazione, come recentemente dimostrato in due università americane. Alla dichiarazione di focolaio epidemico in atto, in entrambi i contesti si è attivata una procedura per l'uso del vaccino 4CMenB non ancora autorizzato negli USA. È stato così possibile organizzare gli interventi di profilassi attiva nei due campus universitari, adottando il primo impiego su larga scala del nuovo vaccino 4CMenB e conseguendo, in tempi relativamente brevi, elevati tassi di copertura vaccinale. A fronte di circa 14000 studenti immunizzati con almeno una dose, non è stata segnalata alcuna problematica di eventi avversi conseguenti all'immunizzazione; ad oggi non si sono verificati casi nei soggetti che hanno ricevuto il vaccino. Come conseguenza dei due focolai descritti, è oggi in corso la valutazione da parte dell'FDA per l'estensione dell'uso del vaccino 4CMenB negli Stati Uniti negli adolescenti e giovani adulti. PMID:25916017

  14. [Mortality from respiratory diseases in the provinces of Apulia Region (Southern Italy) from 1933 to 2010].

    PubMed

    Montinari, Maria Rosa; Gianicolo, Emilio Antonio Luca; Vigotti, Maria Angela

    2016-01-01

    OBIETTIVI: valutare l'andamento temporale della mortalità per patologie respiratorie nelle province pugliesi utilizzando dati omogenei per fonte e metodologia di calcolo. DISEGNO: analisi ecologica storica degli andamenti temporali di mortalità per tumori e patologie dell'apparato respiratorio nelle province pugliesi, in Puglia e nelle ripartizioni geografiche italiane dal 1933 al 2010. SETTING E PARTECIPANTI: i dati di mortalità e le popolazioni residenti sono di fonte Istat. Sono state esaminate tutte le cause di decesso, il tumore della laringe, il tumore del polmone, l'insieme dei tumori respiratori, la bronchite, la polmonite e la broncopolmonite considerate congiuntamente, e l'insieme delle patologie respiratorie. Le analisi sono disaggregate per sesso dal 1969. PRINCIPALI MISURE DI OUTCOME: rapporti standardizzati di mortalità (SMR%) in riferimento all'Italia, con intervalli di confidenza al 95%, e tassi di mortalità standardizzati col metodo diretto (TSD ) in riferimento alla popolazione standard europea. RISULTATI: dal 1933 al 2010, i TSD per tumori respiratori e per bronchiti diminuiscono in tutte le aree analizzate. Tuttavia, nelle province di Taranto, Brindisi e Lecce, l'SMR% per tumori respiratori, inferiore al riferimento nazionale fino agli anni Sessanta, si allinea (a Brindisi) e supera (a Lecce e Taranto) il riferimento negli anni successivi. Nelle province di Foggia e Bari il numero dei decessi per tumore del polmone è costantemente inferiore all'atteso. CONCLUSIONI: la ricostruzione storica e l'analisi dei trend temporali di mortalità dal 1933 al 2010 mostrano alcune criticità sanitarie in periodi specifici. L'elaborazione dei dati di mortalità per un arco temporale di circa 80 anni ha messo in evidenza la maggiore rilevanza di queste criticità con l'avvio dello sviluppo industriale.

  15. Transepithelial corneal collagen crosslinking for keratoconus: qualitative investigation by in vivo HRT II confocal analysis.

    PubMed

    Caporossi, Aldo; Mazzotta, Cosimo; Baiocchi, Stefano; Caporossi, Tomaso; Paradiso, Anna Lucia

    2012-01-01

    This was a qualitative investigation of corneal microstructural modifications in keratoconic patients undergoing experimental transepithelial crosslinking (TE CXL). Ten patients with keratoconus intolerant to gas-permeable rigid contact lenses were enrolled. Corneal thickness was in the range 350-390 µm at the thinnest point measured by Visante AC optical coherence tomography system (Zeiss, Jena, Germany). All patients underwent TE CXL with 0.1% riboflavin-15% dextran solution supplemented with TRIS plus sodium EDTA (Ricrolin TE, Sooft Italia) according to Siena protocol. In vivo Heidelberg retinal tomograph II laser scanning confocal analysis (Rostock Cornea Module, Heidelberg, Germany) was performed with the following follow-up: preoperative and postoperative assessments at 1, 3, and 6 months. The following morphologic parameters were evaluated: epithelium, subepithelial, and anterior stroma nerve plexi, keratocytes apoptosis, stromal changes, and the endothelium. After TE CXL, epithelial cells showed apoptosis, with mosaic alterations gradually disappearing. Keratocytes apoptosis was variable, superficial, and uneven, with a maximum depth of penetration at about 140 µm, measured from the surface of epithelium. Treatment respected subepithelial and stromal nerves that did not disappear. No variation in cell count or endothelial mosaic was observed. In vivo confocal analysis of corneal modifications induced by TE CXL showed a limited apoptotic affect of this treatment, about one-third of classic epi-off crosslinking procedure. The TE CXL respected sub-basal and anterior stroma nerve fibers, resulting safe for corneal endothelium. According to limited penetration, its mid- to long-term efficacy needs to be determined in different clinical settings related to patient age and keratoconus progression.

  16. Measurements of global UV irradiance at Terranova Bay, Antactica, by a home made narrow band filter radiometer

    NASA Astrophysics Data System (ADS)

    Salvatore, Scaglione; di Sarcina, Ilaria; Flori, Daniele; Menchini, Francesca

    2010-05-01

    Filter radiometers measure the solar radiation in several channels (typically 4 to 7) with a bandwith from 2 to 10 nm. They require less maintenance than the spectroradiometer and they are able to work in hostile environment as for instance the polar regions. The spectral resolution depends on the width at half maximum (FWHM) of the filters and is generally lower than the spectroradiometer resolution (0.5 nm). Other than the robustness of this instruments, the main advantage of the filter radiometers is the high frequency with which all wavelengths can be measured, making this class of instrument well suited for investigating short term irradiance variation. In this work is presented the results of UV irradiance measurements performed by a very narrow band (FWHM less than 1 nm) filter radiometer at Antarctica Italia Base, Mario Zucchelli Station, Terranova Bay, lat. 74° 41.6084' south and lon. 164° 05.9224' est. All-dielectric Fabry-Perot filters were manufactured in the laboratories of the Optical Coating Group, ENEA, by the ion beam assistance physical vapor deposition technique. Nine filters select nine different wavelengths in the UV spectral range from 296.5 nm to 377 nm with about 1 minute of measurement period, i.e. each wavelength is measured about 1250 times per day. At the moment the radiometer are permanently located near MZS and the data are daily downloaded in ENEA, Rome, by a dedicated satellite channel. During the Antarctica winter the radiometer will be in standby mode, in this season MZS is closed, and it will be start to measure again in the Antarctica spring.

  17. Comparison between QuikSCAT and buoy wind data in the Ligurian Sea

    NASA Astrophysics Data System (ADS)

    Pensieri, Sara; Bozzano, Roberto; Schiano, Maria Elisabetta

    2010-06-01

    Wind above sea surface plays an important role in the Mediterranean Sea for a large variety of scientific applications (i.e., climatological, meteorological and oceanographic studies). In this work we compare wind vectors obtained from the SeaWinds scatterometer on board the National Aeronautics and Space Administration (NASA) QuikSCAT satellite with wind data measured in situ by an anemometer mounted on the offshore ODAS Italia 1 buoy. This platform is moored in the Central Ligurian Sea, a basin where the wind field is highly variable both in time and space due to the orographic constraints and the thermal contrast between land and sea that give rise to specific local effects. The work covers the period from July 2006 to June 2007. The comparison confirms that the QuikSCAT wind vectors satisfy the accuracy requirements for high wind speeds, but, QuikSCAT skill is less for low wind speed, especially for the direction assessment. These results are in agreement with those of previous investigations but the analysis evidences some issues mistreated until now. The most relevant is the scarceness of data. The satellite passes over the Ligurian Sea only twice a day and data taken under rainy condition and with wind speed lower than 3 ms - 1 are not valid. Thus, the temporal sampling may be not adequate to monitor wind fields and their evolution over this basin where calm condition often occurs and strong perturbations are generally associated to rain. Furthermore, the comparison shows that it may be difficult to recognize spurious values obtained from QuikSCAT when the true wind speed is lower than 3 ms - 1 without a reference at sea.

  18. Changes in urinary amino acids excretion in relationship with muscle activity markers over a professional cycling stage race: in search of fatigue markers.

    PubMed

    Corsetti, Roberto; Barassi, Alessandra; Perego, Silvia; Sansoni, Veronica; Rossi, Alessandra; Damele, Clara Anna Linda; Melzi D'Eril, Gianlodovico; Banfi, Giuseppe; Lombardi, Giovanni

    2016-01-01

    The aim of this study was to identify the relationship between metabolic effort, muscular damage/activity indices, and urinary amino acids profile over the course of a strenuous prolonged endurance activity, as a cycling stage race is, in order to identify possible fatigue markers. Nine professional cyclists belonging to a single team, competing in the Giro d'Italia cycling stage race, were anthropometrically characterized and sampled for blood and urine the day before the race started, and on days 12 and 23 of the race. Diet was kept the same over the race, and power output and energy expenditure were recorded. Sera were assayed for muscle markers (lactate dehydrogenase, aspartate aminotransferase, and creatine kinase activities, and blood urea nitrogen), and creatinine, all corrected for plasma volume changes. Urines were profiled for amino acid concentrations, normalized on creatinine excretion. Renal function, in terms of glomerular filtration rate, was monitored by MDRD equation corrected on body surface area. Creatine kinase activity and blood urea were increased during the race as did serum creatinine while kidney function remained stable. Among the amino acids, taurine, glycine, cysteine, leucine, carnosine, 1-methyl histidine, and 3-methyl histidine showed a net decreased, while homocysteine was increased. Taurine and the dipeptide carnosine (β-alanyl-L-histidine) were significantly correlated with the muscle activity markers and the indices of effort. In conclusion, the metabolic profile is modified strikingly due to the effort. Urinary taurine and carnosine seem useful tools to evaluate the muscle damage and possibly the fatigue status on a long-term basis.

  19. Multiplex loop-mediated isothermal amplification (M-LAMP) assay for the detection of influenza A/H1, A/H3 and influenza B can provide a specimen-to-result diagnosis in 40 min with single genome copy sensitivity.

    PubMed

    Mahony, James; Chong, Sylvia; Bulir, David; Ruyter, Alexandra; Mwawasi, Ken; Waltho, Daniel

    2013-09-01

    Rapid isothermal amplification methods have recently been introduced and they offer significant advantages over PCR. To develop a rapid and sensitive M-LAMP assay for the detection of influenza A (H1 and H3) and B that does not require RNA extraction. We designed six primers targeting the matrix genes of influenza H1 and H3 and the NS1 gene of influenza B and developed a M-LAMP assay using a commercially available Master Mix and a real time fluorometer (Genie II, Optigene, UK) that displays real time amplification, time to positivity and amplicon annealing temperature (Tm). M-LAMP was evaluated against PCR by testing 202 nasopharyngeal (NP) specimens. Optimized M-LAMP was rapid with a mean amplification time of 12 min (compared with 90-120 min for PCR), had an analytical sensitivity of 1 genome equivalent (ge), and could distinguish influenza A including subtypes A/H1 and A/H3 from influenza B by Tm. M-LAMP detected 26/28 influenza A/H1, 27/27 influenza A/H3 and 39/39 influenza B specimens and had a combined sensitivity and specificity for detecting influenza (A and B) of 97.9% (92/94) and 100% (108/108), respectively. The rapid amplification time of LAMP coupled with a novel 10-min specimen preparation procedure consisting of vortexing and heating in M-Swab diluent (Copan Italia) provided a rapid result. M-LAMP had excellent sensitivity and specificity for detecting influenza A and B in NP specimens and when used together with a rapid specimen processing method provided a specimen-to-result diagnosis in 30 min. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. A microsatellite study for determination of allelic variation of Kurdish population-Kurdistan region-Iraq

    NASA Astrophysics Data System (ADS)

    Murad, Media J.; Amin, Bushra K.

    2017-09-01

    The purpose of this study was detecting genetic variations for the Kurdish population in Kurdistan region-Iraq, using fifteen autosomal STR loci. Buccal swabs were collected and depositing on Nucleic Card (Copan, Italia Spa) from 302 healthy unrelated Iraqi Kurds in five provinces of Kurdistan region-Iraq. Fifteen autosomal STR loci are D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, FGA and Amelogenin included in the AmpFlSTR Identifiler® Direct PCR Amplification Kit (Applied Biosystems, Foster City, CA, USA). No significant departure from Hardy Weinberg Equilibrium (HWE) expectations were observed in 10 from 15 STR loci analyzed (a 5% significance level was taken). The exceptions were the CSF1PO, D3S1358, D13S317, D16S539 and D2S1338 loci. Statistical parameters of forensic efficiencies were estimated for the loci, based on allelic frequencies. The mean of observed heterozygosity, expected heterozygosity and PIC values across the 15 loci were 0.762, 0.797 and 0.768 respectively, indicating high gene diversity. The combined probability of exclusion, power of discrimination, probability of matching value for all the 15 STR loci were 0.9999968; 0.9999999 and 4.966×10-17, respectively. These parameters indicated the importance of the loci for forensic genetic purposes and paternity testing.

  1. Modulation of Protein Phosphorylation, N-Glycosylation and Lys-Acetylation in Grape (Vitis vinifera) Mesocarp and Exocarp Owing to Lobesia botrana Infection*

    PubMed Central

    Melo-Braga, Marcella N.; Verano-Braga, Thiago; León, Ileana R.; Antonacci, Donato; Nogueira, Fábio C. S.; Thelen, Jay J.; Larsen, Martin R.; Palmisano, Giuseppe

    2012-01-01

    Grapevine (Vitis vinifera) is an economically important fruit crop that is subject to many types of insect and pathogen attack. To better elucidate the plant response to Lobesia botrana pathogen infection, we initiated a global comparative proteomic study monitoring steady-state protein expression as well as changes in N-glycosylation, phosphorylation, and Lys-acetylation in control and infected mesocarp and exocarp from V. vinifera cv Italia. A multi-parallel, large-scale proteomic approach employing iTRAQ labeling prior to three peptide enrichment techniques followed by tandem mass spectrometry led to the identification of a total of 3059 proteins, 1135 phosphorylation sites, 323 N-linked glycosylation sites and 138 Lys-acetylation sites. Of these, we could identify changes in abundance of 899 proteins. The occupancy of 110 phosphorylation sites, 10 N-glycosylation sites and 20 Lys-acetylation sites differentially changed during L. botrana infection. Sequence consensus analysis for phosphorylation sites showed eight significant motifs, two of which containing up-regulated phosphopeptides (X-G-S-X and S-X-X-D) and two containing down-regulated phosphopeptides (R-X-X-S and S-D-X-E) in response to pathogen infection. Topographical distribution of phosphorylation sites within primary sequences reveal preferential phosphorylation at both the N- and C termini, and a clear preference for C-terminal phosphorylation in response to pathogen infection suggesting induction of region-specific kinase(s). Lys-acetylation analysis confirmed the consensus X-K-Y-X motif previously detected in mammals and revealed the importance of this modification in plant defense. The importance of N-linked protein glycosylation in plant response to biotic stimulus was evident by an up-regulated glycopeptide belonging to the disease resistance response protein 206. This study represents a substantial step toward the understanding of protein and PTMs-mediated plant-pathogen interaction shedding

  2. Choosing a negative pressure ventilation pump: are there any important differences?

    PubMed

    Smith, I E; King, M A; Shneerson, J M

    1995-10-01

    Five negative pressure ventilator pumps were assessed to determine whether there were any differences in performance which were likely to be of clinical importance. The pumps tested were the NEV-100 (Lifecare Inc.), the Negavent Respirator DA-1 (Dima Italia), the Thompson Maxivent (Puritan Bennett), the CCP-001 and Newmarket pumps (Si-Plan Electronics Research Ltd). A patient model was employed to investigate the relationship between the pressure waveform of each pump and the tidal volume generated, the stability of performance on a continuous 8 h test, and the response to a change in leak. On the continuous tests, the stability was better than +/- 1% for the inspiratory/expiratory (I:E) ratio and rate, and better than +/- 10% for the peak negative pressure for all of the pumps. The Negavent and NEV-100 pumps generated a square wave of pressure and for the same peak negative pressure produced a tidal volume up to 30% greater than the CCP-001 and the Newmarket pumps, which produced a half sine wave. The Maxivent produced an intermediate waveform, with a plateau at peak negative pressure but a curved decay back to atmospheric pressure. It is argued that if the pressure of the pumps producing a half sine wave is made more negative to compensate and produce an equivalent tidal volume, they are more likely to induce upper airway obstruction. The leak compensation of the NEV-100 and Negavent pumps was nearly complete but took several breaths to develop, the CCP-001 and Newmarket pumps had a very rapid compensation but this was less complete, whilst the Maxivent has no mechanism for leak compensation. From these results, it seems that in patients liable to upper airway obstruction the NEV-100 and Negavent pumps would be advantageous, whilst when rapidly changing leaks impair the efficiency of negative pressure ventilation the CCP-001 and Newmarket pumps would be preferable. The Maxivent pump seems to offer no advantages.

  3. The association between overweight and illegal drug consumption in adolescents: is there an underlying influence of the sociocultural environment?

    PubMed

    Denoth, Francesca; Siciliano, Valeria; Iozzo, Patricia; Fortunato, Loredana; Molinaro, Sabrina

    2011-01-01

    The aims of the study were to: a) Examine the distribution of gender-stratified body mass index (BMI), eating attitudes and use of addictive substances, under the hypothesis of a confluent prevalence of weight abnormalities, eating disorders and substance abuse. b) Demonstrate the extent to which family, peer-related and psychosocial factors are common elements in categories of compulsive behaviour. In the present cross-sectional study, data were collected through self reported questionnaires administered to a large sample of 33,185 15-19 years old adolescents (ESPAD®Italia), divided into weight categories based on the BMI percentile distribution. Multinomial analyses were adopted to address the influence of social, family, leisure time factors, Eating Attitude Test (EAT26) on the association between weight categories and drug use. Recent drugs use was more frequent in overweight and underweight adolescents (p<0.05), especially in females. An EAT26 score ≥20 was more common in overweight adolescents. Multinomial analysis abolished the relationship between overweight and the use of most drugs, implicating self-esteem, parents' educational level, and friendships as mediators of the association. Within the overweight category, adolescents reporting recent drug use, showed greater frequency of having drug-abusing friends (∼80%), and severe problems with parents and school (∼30%) compared to overweight adolescents without recent drug use. The frequent association of overweight and substance use and the presence of common underlying social factors, highlights the need for an interdisciplinary approach involving individual-focused treatment models as well as public health, social and environmental changes to reduce food- and substances-related problems.

  4. Modulation of protein phosphorylation, N-glycosylation and Lys-acetylation in grape (Vitis vinifera) mesocarp and exocarp owing to Lobesia botrana infection.

    PubMed

    Melo-Braga, Marcella N; Verano-Braga, Thiago; León, Ileana R; Antonacci, Donato; Nogueira, Fábio C S; Thelen, Jay J; Larsen, Martin R; Palmisano, Giuseppe

    2012-10-01

    Grapevine (Vitis vinifera) is an economically important fruit crop that is subject to many types of insect and pathogen attack. To better elucidate the plant response to Lobesia botrana pathogen infection, we initiated a global comparative proteomic study monitoring steady-state protein expression as well as changes in N-glycosylation, phosphorylation, and Lys-acetylation in control and infected mesocarp and exocarp from V. vinifera cv Italia. A multi-parallel, large-scale proteomic approach employing iTRAQ labeling prior to three peptide enrichment techniques followed by tandem mass spectrometry led to the identification of a total of 3059 proteins, 1135 phosphorylation sites, 323 N-linked glycosylation sites and 138 Lys-acetylation sites. Of these, we could identify changes in abundance of 899 proteins. The occupancy of 110 phosphorylation sites, 10 N-glycosylation sites and 20 Lys-acetylation sites differentially changed during L. botrana infection. Sequence consensus analysis for phosphorylation sites showed eight significant motifs, two of which containing up-regulated phosphopeptides (X-G-S-X and S-X-X-D) and two containing down-regulated phosphopeptides (R-X-X-S and S-D-X-E) in response to pathogen infection. Topographical distribution of phosphorylation sites within primary sequences reveal preferential phosphorylation at both the N- and C termini, and a clear preference for C-terminal phosphorylation in response to pathogen infection suggesting induction of region-specific kinase(s). Lys-acetylation analysis confirmed the consensus X-K-Y-X motif previously detected in mammals and revealed the importance of this modification in plant defense. The importance of N-linked protein glycosylation in plant response to biotic stimulus was evident by an up-regulated glycopeptide belonging to the disease resistance response protein 206. This study represents a substantial step toward the understanding of protein and PTMs-mediated plant-pathogen interaction shedding

  5. Emergence of Ciprofloxacin-Resistant Salmonella enterica Serovar Typhi in Italy.

    PubMed

    García-Fernández, Aurora; Gallina, Silvia; Owczarek, Slawomir; Dionisi, Anna Maria; Benedetti, Ildo; Decastelli, Lucia; Luzzi, Ida

    2015-01-01

    In developed countries, typhoid fever is often associated with persons who travel to endemic areas or immigrate from them. Typhoid fever is a systemic infection caused by Salmonella enterica serovar Typhi. Because of the emergence of antimicrobial resistance to standard first-line drugs, fluoroquinolones are the drugs of choice. Resistance to ciprofloxacin by this Salmonella serovar represents an emerging public health issue. Two S. enterica ser. Typhi strains resistant to ciprofloxacin (CIP) were reported to the Italian surveillance system for foodborne and waterborne diseases (EnterNet-Italia) in 2013. The strains were isolated from two Italian tourists upon their arrival from India. A retrospective analysis of 17 other S. enterica ser. Typhi strains isolated in Italy during 2011-2013 was performed to determine their resistance to CIP. For this purpose, we assayed for susceptibility to antimicrobial agents and conducted PCR and nucleotide sequence analyses. Moreover, all strains were typed using pulsed-field gel electrophoresis to evaluate possible clonal relationships. Sixty-eight percent of the S. enterica ser. Typhi strains were resistant to CIP (MICs, 0.125-16 mg/L), and all isolates were negative for determinants of plasmid-mediated quinolone resistance. Analysis of sequences encoding DNA gyrase and topoisomerase IV subunits revealed mutations in gyrA, gyrB, and parC. Thirteen different clonal groups were detected, and the two CIP-resistant strains isolated from the individuals who visited India exhibited the same PFGE pattern. Because of these findings, the emergence of CIP-resistant S. enterica ser. Typhi isolates in Italy deserves attention, and monitoring antibiotic susceptibility is important for efficiently managing cases of typhoid fever.

  6. Italian women's television coverage and audience during the 2004 Athens Olympic Games.

    PubMed

    Capranica, Laura; Tessitore, Antonio; D, Artibale Emanuele; Cortis, Cristina; Casella, Rita; Camilleri, Enrica; Pesce, Caterina

    2008-03-01

    This study aimed at determining the amount of Italian television coverage dedicated to men's and women's sport and the number of male and female viewers during the 2004 Summer Olympic Games. AUDITEL-AGB Nielsen Media Research Italia provided the TV airtime data for the sport events broadcast, which were classified into three categories: men-only, women-only, and mixed-gender. The viewer sample was divided by age and gender and included three audience parameters: mean audience, share, and appreciation index. The last item is calculated from the program duration, audience permanence, and the share related to programs broadcast by other Italian channels. In particular, the appreciation index was used to investigate the relationship between (a) the viewer's and sport participants' gender and (b) the effect of Italian participation and expectations for sport achievement. The data showed that Italian male athletes outnumbered their female counterparts. Women's sport was allotted significantly less airtime than men's sport, but this imbalance was not proportional to the gender difference in the overall athletes' participation in the Games. Although the female audience represented 45% of the total, a significantly higher male mean audience and share were found. On the other hand, the appreciation of men's and women's sport events was balanced after equating for differences in media coverage. Moreover sport achievement might have a positive effect on the trend toward equality of gender coverage, indicating that a global multisport event such as the Olympic Games is central to communicating a national image and identity independently of the athletes' gender.

  7. Association of Problem Gambling with Type of Gambling Among Italian General Population.

    PubMed

    Scalese, Marco; Bastiani, Luca; Salvadori, Stefano; Gori, Mercedes; Lewis, Isabella; Jarre, Paolo; Molinaro, Sabrina

    2016-09-01

    The origin of gambling disorders is uncertain; however, research has shown a tendency to focus on specific types of games as a potential important risk factor. The principal aim of this study is to examine the relationships between types of gambling practices and gambling disorder. The data were extracted from IPSAD-Italia(®) 2010-2011 (Italian Population Survey on Alcohol and other Drugs), a survey among the Italian general population which collects socio-cultural information, information about the use of drugs, legal substances and gambling habits. In order to identify the "problem gambler" we used the Problem Gambling Severity Index. Three groups are considered in this analysis: no-risk gamblers, low-risk gamblers, moderate-risk/problem gamblers. Type of gambling practice was considered among two types of gambler: one-game players and multi-games players. 1.9 % of multi-game players were considered problem gamblers, only 0.6 % of one-game players were problem gamblers (p < 0.001). The percentage of players who were low and moderate-risk gamblers was approximately double among multi-game players, with 14.4 % low-risk and 5.8 % moderate-risk; compared with 7.7 % low-risk and 2.5 % moderate risk among one-game players. Results of ordinal logistic regression analysis confirmed that higher level of gambling severity was associated with multi-game players (OR = 2.23, p < 0.0001). Video-poker/slot-machines show the highest association with gambling severity among both one-game players and multi-game players, with scores of OR equal to 4.3 and 4.5 respectively. These findings suggest a popular perception of risk associated with this type of gambling for the development of gambling problems.

  8. MIOSAT Mission Scenario and Design

    NASA Astrophysics Data System (ADS)

    Agostara, C.; Dionisio, C.; Sgroi, G.; di Salvo, A.

    2008-08-01

    MIOSAT ("Mssione Ottica su microSATellite") is a low-cost technological / scientific microsatellite mission for Earth Observation, funded by Italian Space Agency (ASI) and managed by a Group Agreement between Rheinmetall Italia - B.U. Spazio - Contraves as leader and Carlo Gavazzi Space as satellite manufacturer. Several others Italians Companies, SME and Universities are involved in the development team with crucial roles. MIOSAT is a microsatellite weighting around 120 kg and placed in a 525 km altitude sun-synchronuos circular LEO orbit. The microsatellite embarks three innovative optical payloads: Sagnac multi spectral radiometer (IFAC-CNR), Mach Zehender spectrometer (IMM-CNR), high resolution pancromatic camera (Selex Galileo). In addition three technological experiments will be tested in-flight. The first one is an heat pipe based on Marangoni effect with high efficiency. The second is a high accuracy Sun Sensor using COTS components and the last is a GNSS SW receiver that utilizes a Leon2 processor. Finally a new generation of 28% efficiency solar cells will be adopted for the power generation. The platform is highly agile and can tilt along and cross flight direction. The pointing accuracy is in the order of 0,1° for each axe. The pointing determination during images acquisition is <0,02° for the axis normal to the boresight and 0,04° for the boresight. This paper deals with MIOSAT mission scenario and definition, highlighting trade-offs for mission implementation. MIOSAT mission design has been constrained from challenging requirements in terms of satellite mass, mission lifetime, instrument performance, that have implied the utilization of satellite agility capability to improve instruments performance in terms of S/N and resolution. The instruments provide complementary measurements that can be combined in effective ways to exploit new applications in the fields of atmosphere composition analysis, Earth emissions, antropic phenomena, etc. The Mission

  9. View of eastern coast of Sicily area

    NASA Image and Video Library

    1973-08-15

    SL3-87-355 (July-September 1973) --- A vertical view of the eastern coast of Sicily area is seen in this Skylab 3 Earth Resources Experiments Package S190-B (five-inch earth terrain camera) infrared photograph taken from the Skylab space station in Earth orbit. Mount Etna, the highest volcano in Europe (10,958 feet), is still active as evidenced by the thin plume of smoke emanating from its crest. (The altitude is approximate because the height of the volcano changes with each eruption). On the flanks of Etna recent lava flows appear black in contrast to the older flows and volcanic debris that are red. Numerous small, circular cinder cones on the flanks represent sites of previous eruptions. Catania, on the Mediterranean coast south of Etna, is the largest of several cities and villages which appear as light-gray patches on the lower slopes of the volcano. Plano de Catania, south of the city of Catania, is outlined by polygonal light and dark agricultural tracts. Several lakes, the largest of which is Lake Pozzillo, show up as dark blue in the photograph. The unusual colors in the picture are due to the use of color infrared film in which vegetation appears red. This is very evident on the slopes of Etna, in the Monti Nebrodi area at upper let, and in the local areas in the lower part of the picture. Studies of Mount Etna and related volcanic features will be undertaken by Professor Roberto Cassinis of Servizio Geologio d?Italia, Rome. Federal agencies participating with NASA on the EREP project are the Departments of Agriculture, Commerce, Interior, the Environmental Protection Agency and the Corps of Engineers. All EREP photography is available to the public through the Department of Interior?s Earth Resources Observation Systems Data Center, Sioux Falls, South Dakota, 57198. Photo credit: NASA

  10. The Mice Drawer System (MDS) Experiment and the Space Endurance Record-Breaking Mice

    PubMed Central

    Cancedda, Ranieri; Liu, Yi; Ruggiu, Alessandra; Tavella, Sara; Biticchi, Roberta; Santucci, Daniela; Schwartz, Silvia; Ciparelli, Paolo; Falcetti, Giancarlo; Tenconi, Chiara; Cotronei, Vittorio; Pignataro, Salvatore

    2012-01-01

    The Italian Space Agency, in line with its scientific strategies and the National Utilization Plan for the International Space Station (ISS), contracted Thales Alenia Space Italia to design and build a spaceflight payload for rodent research on ISS: the Mice Drawer System (MDS). The payload, to be integrated inside the Space Shuttle middeck during transportation and inside the Express Rack in the ISS during experiment execution, was designed to function autonomously for more than 3 months and to involve crew only for maintenance activities. In its first mission, three wild type (Wt) and three transgenic male mice over-expressing pleiotrophin under the control of a bone-specific promoter (PTN-Tg) were housed in the MDS. At the time of launch, animals were 2-months old. MDS reached the ISS on board of Shuttle Discovery Flight 17A/STS-128 on August 28th, 2009. MDS returned to Earth on November 27th, 2009 with Shuttle Atlantis Flight ULF3/STS-129 after 91 days, performing the longest permanence of mice in space. Unfortunately, during the MDS mission, one PTN-Tg and two Wt mice died due to health status or payload-related reasons. The remaining mice showed a normal behavior throughout the experiment and appeared in excellent health conditions at landing. During the experiment, the mice health conditions and their water and food consumption were daily checked. Upon landing mice were sacrificed, blood parameters measured and tissues dissected for subsequent analysis. To obtain as much information as possible on microgravity-induced tissue modifications, we organized a Tissue Sharing Program: 20 research groups from 6 countries participated. In order to distinguish between possible effects of the MDS housing conditions and effects due to the near-zero gravity environment, a ground replica of the flight experiment was performed at the University of Genova. Control tissues were collected also from mice maintained on Earth in standard vivarium cages. PMID:22666312

  11. Os-Hf isotopes of the ultrapotassic rocks in southern Tibet: Significant crustal input into the mantle source region

    NASA Astrophysics Data System (ADS)

    Zhao, Z.; Widom, E.; Meng, Q.; Niu, Y.; Zhu, D.; Mo, X.; Barry, T.

    2010-12-01

    The post-collisional mafic ultrapotassic (ultra-K) magmatism in the western Lhasa terrane, southern Tibet, has been well-studied in the past decade. The model of low-degree partial melting of an enriched subcontinental lithospheric mantle has been proposed to be responsible for the origin of the ultra-K rocks on the basis of trace element and Sr-Nd-Pb-O isotope data (Miller et al., 1999, J. Petrology; Ding et al., 2003, J. Petrology; Gao et al., 2009, J. Petrology; Zhao et al., 2009, Lithos). Here, we report both Os and Hf isotopic data on the same ultra-K samples discussed in Zhao et al. (2009). The rocks have suprachondritic 187Os/188Os (0.1315-0.4828) and sub-chondritic to MORB-like Re/Os ratios (0.019-15.75). In the 187Os/188Os vs. Re/Os plot, the data show a notable trend towards the Himalayan crustal components. The 176Hf/177Hf ratios of 0.282204 to 0.282554 correspond to ɛHf values of -20.1 to -7.9. In the ɛHf vs. ɛNd plot, these mafic ultra-K rocks show strong crustal signatures, similar to, but more enriched than, the lamproites from Spain and Italia (Prelević et al., 2010, Lithos). They also show a linear trend that coincides with the Hf-Nd isotopic array defined by igneous rocks, suggesting significant contributions of some mature continental crustal material in their petrogenesis. The radiogenic Os could be interpreted as resulting from crustal assimilation, but more likely reflects increasing contributions from metasomatic components (Schaefer et al., 2000, Geology). Taking together all the trace element data, Os-Hf-Nd data and petrological data, we suggest that the petrogenesis of the mantle xenolith-bearing ultra-K rocks in southern Tibet involves melting of enriched upper mantle whose enrichments may be genetically associated with metasomatism by a melt component derived from subducted Himalayan continental crustal materials.

  12. Model based historical runoff contribution from an Alpine glacier

    NASA Astrophysics Data System (ADS)

    Zoccatelli, Davide; Bonato, Paola; Carturan, Luca; Dalla Fontana, Giancarlo; De Blasi, Fabrizio; Borga, Marco

    2016-04-01

    The aim of this work is to analyze how climatic variability and glacier retreat impact the water balance of a small (8.5 km2) glaciarised catchment in the Eastern Italia Alps over a 30 year (1983-2013) period. The analysis is carried out by coupling local high quality data and a glacio-hydrological model able to simulate both the glacier and hydrology dynamics. Runoff contribution from glacier ice is related with trends in climatic variables and with glacier retreat. The area analyzed is the headwater of Noce Bianco river basin, lying in the Ortles-Cevedale group and including the La Mare glacier. During the study period the glacier area decreased from 4.7 km2 (50% basin area) to 3.47 km2 (40% basin area). In this area the following observations are available: 30 years of daily meteorological data at high elevation close to the catchment; three DTMs of the glacier, covering the entire period, which enable the calculation of the volume change and geodetic mass balance; direct glaciological mass balance observations over the period 2003-2013; discharge measurement at the catchment outlet over the period 2007-2013. The data availability and the significant shrinking of the glacier during the analyzed period make this catchment ideal for studying the hydrological impacts of glacier retreat. The semi-distributed conceptual model includes a snow and glacier accumulation and ablation module, based on temperature-radiation index and a glacier retreat model. The glacier retreat model allows to use the annual simulated glacier mass balance to update the glacier area (Huss et al., 2010). The model simulations are carried out from 1983 to 2013. We show that the model is able to capture adequately the measured daily discharge, the observed changes in glacier area and their spatial distribution. The contribution of glacier ice meltwater to annual runoff is below 10% in the first decade of simulation. This variable however showed a clear increasing trend, with peaks for single

  13. Volcanic Ash Monitoring and FOrecaSting between Sicilia and Malta arEa and sharinG of the resUlts foR aviatiOn safety: the VAMOS SEGURO project

    NASA Astrophysics Data System (ADS)

    Scollo, Simona; Azzopardi, Francelle; Boselli, Antonella; Coltelli, Mauro; Ellul, Raymond; Leto, Giuseppe; Pisani, Gianluca; Prestifilippo, Michele; Saliba, Martin; Schiavone, Joseph; Spata, Gaetano; Spinelli, Nicola; Wang, Xuan; Zanmar Sanchez, Ricardo

    2013-04-01

    Mt. Etna, in Italy, is one of the most active volcanoes in the world and during its frequent explosive episodes, eruption columns rise to several kilometers and fine ash is dispersed hundreds kilometers away from the vent reaching the neighboring countries. The Maltese Islands, for example, are situated at the center of the Mediterranean, only 100 km south of Sicily and, due to the close proximity, have been already affected by the past Etna volcanic activity. A reliable monitoring and forecasting system of Etna volcanic ash has to include all areas that could be reached by volcanic ash. For this reason, a new research project named VAMOS SEGURO, has been recently funded by Programma di Cooperazione Transfrontaliera Italia-Malta 2007-2013, with the aim to reduce the impact that Etna's explosive activity has in the area between Sicily and Malta. This project is developed within a cooperation between the Istituto Nazionale di Geofisica, Osservatorio Etneo, the Istituto Nazionale di Astrofisica (INAF), Comune of Montedoro, in Caltanissetta, the University of Malta, and Consorzio Interuniversitario per le Scienze Fisiche della Materia (CNISM). In this project, several instruments (e.g. aerosol optical depth analyzer, microbalance, laser cascade instrument, meteorological stations, aethelometer) have been installed at Giordan lighthouse at Xewkija, in Gozo, managed by the University of Malta. Furthermore, an innovative Lidar system with scanning capability, has been designed and realized by CNISM and is able to indentify the area affected by volcanic ash in Sicily and quantify the ash concentration in atmosphere. The Lidar may be transported and installed in the INAF astronomical observatories of Noto and Serra La Nave, only 7 km away from the Etna summits, and in Montedoro. Finally, an automatic forecasting system produces dispersal maps for the region between Sicily and Malta and for a typical Etna scenario. Results of simulations are daily visible at www

  14. An improved real-time seismic network in the Central Mediterranean

    NASA Astrophysics Data System (ADS)

    Agius, Matthew; Galea, Pauline; D'Amico, Sebastiano

    2014-05-01

    The Central Mediterranean is a region of active tectonics characterised by the interaction of a number of varied and sometimes poorly understood processes. Superimposed on the convergent scenario of the African plate pushing northwestward, a NE-SW directed extensional regime is active in the Sicily Channel, expressed in the form of a seismically active east-west trending system of strike-slip lineaments and a series of pull-apart grabens. The offshore seismicity of the Sicily channel, generally limited to magnitudes below 4.5, is normally difficult to quantify precisely, due to poor station coverage, yet it is believed that its analysis will considerably improve our understanding of the processes affecting the region. We present recent improvements to real and virtual seismic networking in the Central Mediterranean, based at the Seismic Monitoring and Research Unit (SMRU), University of Malta. Within the project SIMIT (B1-2.19/11) funded by the Italia-Malta Operational Programme 2007-2013, earthquake monitoring on the Maltese Islands is being upgraded through the installation of a further two broadband stations, one of which will be on the smaller island of Gozo. A new network, ML (Malta Seismic Network), has been internationally registered with the FDSN. At the same time, the installation and implementation of SeisComP3 has enabled the setting up of a virtual, real-time Central Mediterranean network, made up of 18 stations in Southern Italy (including Sicily, Lampedusa and Pantelleria) belonging to the Istituto Nazionale di Geofisica e Vulcanologia, 3 stations in Tunisia (National Institute of Meteorology of Tunisia) and the 3 stations on the Maltese Islands. This will allow us to rapidly perform more accurate hypocentral locations in the region. The virtual network, which also incorporates a number of more distant stations, has been tuned to issue SMS alerts for potentially felt events in the Sicily Channel detected by the network, and for strong earthquakes

  15. Recent developments in the setting up of the Malta Seismic Network

    NASA Astrophysics Data System (ADS)

    Agius, Matthew; Galea, Pauline; D'Amico, Sebastiano

    2015-04-01

    Weak to moderate earthquakes in the Sicily Channel have until now been either poorly located or left undetected. The number of seismic stations operated by various networks: Italy (INGV), Tunisia (TT), and Libya (LNSN) have now improved considerably, however most of the seismicity occurs offshore, in the central part of the Channel, away from the mainland stations. Seismic data availability from island stations across the Channel has been limited or had intermittent transmission hindering proper real-time earthquake monitoring and hypocentre relocation. In order to strengthen the seismic monitoring of the Sicily Channel, in particular the central parts of the Channel, the Seismic Monitoring and Research Unit (SMRU), University of Malta, has, in the last year, been installing a permanent seismic network across the Maltese archipelago: the Malta Seismic Network (ML). Furthermore the SMRU has upgraded its IT facilities to run a virtual regional seismic network composed of the stations on Pantelleria and Lampedusa, together with all the currently publicly available stations in the region. Selected distant seismic stations found elsewhere in the Mediterranean and across the globe have also been incorporated in the system in order to enhance the overall performance of the monitoring and to detect potentially damaging regional earthquakes. Data acquisition and processing of the seismic networks are run by SeisComP. The new installations are part of the project SIMIT (B1-2.19/11) funded by the Italia-Malta Operational Programme 2007-2013. The new system allows the SMRU to rapidly perform more accurate hypocentre locations in the region, and issue automatic SMS alert for potentially felt events in the Sicily Channel detected by the network and for strong earthquakes elsewhere. Within the SIMIT project, the alert system will include civil protection departments in Malta and Sicily. We present the recent developments of the real and virtual seismic network, and discuss the

  16. [Population health surveillance of the general population living near Turin (Northern Italy) incinerator (SPoTT): methodology of the study].

    PubMed

    Bena, Antonella; Chiusolo, Monica; Orengia, Manuela; Cadum, Ennio; Farina, Elena; Musmeci, Loredana; Procopio, Enrico; Salamina, Giuseppe

    2016-01-01

    Si intende qui descrivere il sistema di sorveglianza sugli effetti sulla salute (SpoTT) dell'inquinamento ambientale nelle aree circostanti l'inceneritore di Torino. SPoTT ha 3 linee di attività: 1. monitoraggio epidemiologico degli effetti a breve termine attraverso analisi temporali e misura della correlazione tra livelli giornalieri di emissioni dell'impianto e andamento degli eventi individuati dagli archivi dei dimessi (SDO), di pronto soccorso e di mortalità; sono coinvolti coloro che nel 2013-2018 risiedevano nell'area di ricaduta delle emissioni; 2. sorveglianza epidemiologica degli effetti a lungo termine, stimando tassi standardizzati di mortalità e morbosità; a ogni soggetto è attribuito il valore stimato di esposizione cumulato nel tempo caratteristico della residenza anagrafica; le informazioni sulla salute sono reperite dagli archivi SDO, di mortalità e dai certificati di assistenza al parto; sono studiati due decenni pre-post l'avvio dell'impianto: 2003-2012 e 2013-2022; 3. monitoraggio biologico con misurazione pre-post di metalli, PCDD/F, PCB, OH-IPA; sono coinvolti 196 residenti esposti e 196 di controllo di 35-69 anni, campionati a caso dalle anagrafi comunali; sono effettuate misure di funzionalità endocrina e respiratoria, pressione arteriosa, rischio cardiovascolare; l'esposizione cumulativa sarà stimata per ciascuna persona campionata integrando l'indirizzo di residenza, il tempo di permanenza in ciascun indirizzo e i dati ricavati dai modelli di ricaduta; sarà costituita una biobanca per future indagini di laboratorio; sono coinvolti anche 20 allevatori e i lavoratori dell'impianto. Una quarta linea di attività, non descritta in questo articolo, riguarda il monitoraggio della salute dei lavoratori addetti all'impianto. SPoTT è il primo studio in Italia su inceneritori e salute che adotta un disegno di studio longitudinale di adeguata potenza sia per i residenti sia per i lavoratori. I primi risultati sono attesi nel corso del 2016.

  17. Sinuosity change of the Po River near Cremona (Northern Italy) - a result of neotectonic activity?

    NASA Astrophysics Data System (ADS)

    Petrovszki, Judit; Timár, Gábor

    2010-05-01

    In the map sheets of the Second Military Survey of the Habsburg Empire, Lombardia, Parma, Modena and Venice also can be seen (Timár et al., 2006). This area was surveyed between 1818 and 1829. In these map sheets, we can also follow the river Po from Vaccarizza to the delta. This river reach is about 350 km long. This river reach was digitized and sinuosity values were calculated with different window sizes, and displayed in a spectrum-like diagram (sinuosity spectra; after van Balen et al., 2008). At Cremona, a significante sinuosity change were identified. The sinuosity increasing, and we have high sinuosity values. In the summarizing geological map of Italy (Compagnoni and Calluzzo, 2004), at this place, a tectonic line was identified. So probably this fault line invokes the sinuosity change on the river. The vertical movements indicated on the maps are just the opposite like they would be according to the flume experiments of Ouchi (1985). In the case of the Po River at Cremona, the decrease of the channel slope results higher sinuosity. The reason is that the rate of the slope and water discharge is higher than it is required by the self-organized meandering and the river parameters fell to the range of the unorganized meandering (cf. Timár, 2003). Another possible explanation could be that the northern tributary, the Adda River has significant sediment load that lowers the sinuosity of the trunk river at the confluence. Compagnoni, B., Galluzzo, F. (eds., 2004): Geological Map of Italy. Agenzia per la Protezione dell'Ambiente per I Servizi Tecnici - Dipartimento Difesa del Suolo, Servizio Geologico d'Italia, Rome-Florence-Genoa. Map, scale=1:1250000, especially printed for the 32nd International Geological Congress. Ouchi, S. (1985): Response of alluvial rivers to slow active tectonic movement. Geol. Soc. Am. Bull. 96: 504-515. Timár, G. (2003): Controls on channel sinuosity changes: a case study of the Tisza River, the Great Hungarian Plain. Quaternary

  18. Italian Polar Metadata System

    NASA Astrophysics Data System (ADS)

    Longo, S.; Nativi, S.; Leone, C.; Migliorini, S.; Mazari Villanova, L.

    2012-04-01

    Italian Polar Metadata System C.Leone, S.Longo, S.Migliorini, L.Mazari Villanova, S. Nativi The Italian Antarctic Research Programme (PNRA) is a government initiative funding and coordinating scientific research activities in polar regions. PNRA manages two scientific Stations in Antarctica - Concordia (Dome C), jointly operated with the French Polar Institute "Paul Emile Victor", and Mario Zucchelli (Terra Nova Bay, Southern Victoria Land). In addition National Research Council of Italy (CNR) manages one scientific Station in the Arctic Circle (Ny-Alesund-Svalbard Islands), named Dirigibile Italia. PNRA started in 1985 with the first Italian Expedition in Antarctica. Since then each research group has collected data regarding biology and medicine, geodetic observatory, geophysics, geology, glaciology, physics and atmospheric chemistry, earth-sun relationships and astrophysics, oceanography and marine environment, chemistry contamination, law and geographic science, technology, multi and inter disciplinary researches, autonomously with different formats. In 2010 the Italian Ministry of Research assigned the scientific coordination of the Programme to CNR, which is in charge of the management and sharing of the scientific results carried out in the framework of the PNRA. Therefore, CNR is establishing a new distributed cyber(e)-infrastructure to collect, manage, publish and share polar research results. This is a service-based infrastructure building on Web technologies to implement resources (i.e. data, services and documents) discovery, access and visualization; in addition, semantic-enabled functionalities will be provided. The architecture applies the "System of Systems" principles to build incrementally on the existing systems by supplementing but not supplanting their mandates and governance arrangements. This allows to keep the existing capacities as autonomous as possible. This cyber(e)-infrastructure implements multi-disciplinary interoperability following

  19. Fuel type characterization and potential fire behavior estimation in Sardinia and Corsica islands

    NASA Astrophysics Data System (ADS)

    Bacciu, V.; Pellizzaro, G.; Santoni, P.; Arca, B.; Ventura, A.; Salis, M.; Barboni, T.; Leroy, V.; Cancellieri, D.; Leoni, E.; Ferrat, L.; Perez, Y.; Duce, P.; Spano, D.

    2012-04-01

    BEHAVE fire behavior prediction system (Andrews, 1989) and experimental fuel data. Fire behavior was simulated by setting different weather scenarios representing the most frequent summer meteorological conditions. The simulation outputs (fireline intensity, rate of spread, flame length) were then analyzed for clustering the different fuel types in relation to their potential fire behavior. The results of this analysis can be used to produce fire behavior fuel maps that are important tools in evaluating fire hazard and risk for land management planning, locating and rating fuel treatments, and aiding in environmental assessments and fire danger programs modeling. This work is supported by FUME Project FP7-ENV-2009-1, Grant Agreement Number 243888 and Proterina-C Project, EU Italia-Francia Marittimo 2007-2013 Programme.

  20. The ESI scale, an ethical approach to the evaluation of seismic hazards

    NASA Astrophysics Data System (ADS)

    Porfido, Sabina; Nappi, Rosa; De Lucia, Maddalena; Gaudiosi, Germana; Alessio, Giuliana; Guerrieri, Luca

    2015-04-01

    studies have been reviewed: the destructive 1976 February 4 Guatemala, earthquake (M 7.5) and the 1743 February 20 Nardò, historical earthquake (Salento, Southern Italy). The re-analysis of both earthquakes contributes to define more realistic seismic scenarios in terms of intensities assessment and consequent regional seismic hazards. References Michetti A.M., Esposito E., Guerrieri L., Porfido S., Serva L., Tatevossian R., Vittori E., Audemard F., Azuma T., Clague J., Comerci V., Gurpinar A., Mccalpin J., Mohammadioun B., Mörner N.A, Ota Y. And E. Roghozin - 2007. Intensity Scale ESI 2007, Mem. Descrittive della Carta Geologica d'Italia, Roma, 74, 53 pp

  1. ESA astronauts assigned to Tethered Satellite System mission - STS-75

    NASA Astrophysics Data System (ADS)

    1995-01-01

    The TSS project is a joint NASA/ASI (Italian Space Agency) effort. On STS-75, the five-foot diameter (1.6 metre) Italia built satellite is scheduled to be deployed on the end of a 1 mile long (20 kilometre) conductive tether to study the electrodynamic effects of moving such a tether through the Earth's magnetic field. The experiment will also test techniques for managing the tethered spacecraft at great distances. Throughout the 13-day flight, additional experiments housed in the orbiter's payload bay will give scientists access to s for microgravity and fundamental science investigations. The USMP is designed to provide the foundation for advanced scientific investigations similar to those planned aboard the International Space Station. Claude Nicollier, who is Swiss, was selected by ESA in 1978 as one of three European payload specialists to train for the SPACELAB-1 mission. He was a mission specialist on STS- 46 (31 July-8 August 1992), during which the crew members deployed ESA's retrievable science platform (EURECA) and conducted the first TSS test flight. A few months after his return from this mission Claude Nicollier was selected as mission specialist for STS-61 (2-13 December 1993). He contributed considerably to the complete success of the Hubble Space Telescope repair and refurbishment mission and in particular the replacement of the ESA-provided solar arrays. Maurizio Cheli, an Italian, was selected by ESA in May 1992 along with five other young candidates to expand the corps of ESA astronauts. He has been in Houston since mid-1992 and has qualified as mission specialist at NASA's Johnson Space Center there. STS-75 will be his first Shuttle flight. Marine Corps Lt. Col. Andrew M. Allen will command Space Shuttle Columbia's STS-75 mission. Joining Allen are Air Force Major Scott J. Horowitz, pilot; payload commander Franklin R. Chang-Diaz, Ph. D; Italian Space Agency (ASI) TSS payload specialist Umberto Guidoni, Ph.D; mission specialist Jeffrey A

  2. Soil erosion modelling of the Mediterranean basin in the context of land use and climate changes.

    NASA Astrophysics Data System (ADS)

    Cerdan, Olivier; Desprats, Jean-François; Fouché, Julien; Le Bissonnais, Yves; Cheviron, Bruno; Simonneaux, Vincent; Raclot, Damien; Mouillot, Florent

    2010-05-01

    Hydric erosion is one of the major causes of soil degradation. It results from the interaction of several parameters which vary in space and time. Global warming and the land use changes expected during the 21st century are going to influence the soils deterioration and the erosion processes. In order to protect the soil resource under the current bioclimatic context and prevent the future consequences, it is essential to apprehend the erosion risk. Many studies developed the soil erosion risk modelling at various scales from regional to European scale. The MESOEROS project is the first which aims to understand the soil loss risk on the whole Mediterranean basin for the current climate context and also for the predicting climate changes expected for the 21st century. Two models are used: MESALES (expert rules model) and PESERA (physical based model). Both provide the soil erosion risk into five classes. Model inputs, soils properties (crusting and erodibility), climate data, DEM and land use data, come from the most recent and validated datasets, homogenised on the whole study area. After being calibrated with watersheds data and the PESERA modelling on Europe, the two modelling results are analysed. Both MESALES and PESERA present an erosion risk contrast around the Mediterranean basin. MESALES estimates Italia, Andalusia, Catalan and Aragon regions, western part of Greece and Balkan region as threatened areas while PESERA models the arable region of Castellan y Leon, Near East and the high atlas range in Morocco as subjected to an erosion risk. The two methods model parts of northern Morocco, centre and European part of Turkey, Lebanon and northern Portugal at risk while southern France, Libyan coasts and southern Greece are never threatened. Analyses of the parameter influences on the models and the modelling validation allow understanding the integration of climate change on modelling results. MESALES and PESERA point out an evolution of the soil erosion risk

  3. Past, present and future of Biopan

    NASA Astrophysics Data System (ADS)

    Demets, R.; Schulte, W.; Baglioni, P.

    accident in 2002 necessitated a re-manufacturing and even a partial re-design of BIOPAN, the latter due to today's non-availability of a number of obsolete electrical components. More, heavier and more complex experiments can nowadays be accommodated, the sensors have been upgraded, the experiment temperature management has been improved and power can be provided to a limited set of experiments. BIOPAN is designed and manufactured under ESA contract by Kayser-Threde (Germany), with Kayser Italia (Italy) as sub-contractor for the electronics subsystem and software. The re-entry heat shield is produced by TsSKB-Progress (Russia).

  4. Hypothyroidism in patients with bipolar I disorder treated primarily with lithium.

    PubMed

    Fagiolini, Andrea; Kupfer, David J; Scott, John; Swartz, Holly A; Cook, David; Novick, Danielle M; Frank, Ellen

    2006-01-01

    This study evaluated the frequency and clinical significance of abnormal Thyroid Stimulating Hormone (TSH) and Free Thyroxine Index (FTI) in patients with bipolar I disorder treated primarily with lithium. We evaluated the medical records of 143 participants in the Pittsburgh study of Maintenance Therapies in Bipolar Disorder who did not have a thyroid abnormality at entry. Thirty-six percent of the 143 patients developed abnormal TSH and/or FTI values. Thirty-eight percent of the 135 patients who received lithium developed abnormal TSH and/or FTI, spent significantly longer time in the acute treatment phase (t = -3.6, df = 133, p = .0004), and had significantly higher mean Hamilton Scale for Depression scores over the course of the maintenance phase (t = -2.3, df = 71.6, p = .03). Time on lithium and development of abnormal TSH and/or FTI were positively correlated (r = .25, p = .004). Thyroid dysfunction can be frequent in patients exposed to lithium treatment for bipolar I disorder; it also appears to be correlated with a slower response to acute treatment, and may be related to poorer quality of long-term remission. A prospective study is needed to confirm our findings and determine whether more aggressive thyroid replacement can optimize thyroid function to facilitate clinical recovery. Supported in part by National Institute of Mental Health Grants MH 029618 (Drs. Frank and Fagiolini) and MH 030915 (Drs. Kupfer and Fagiolini), and the Bosin Memorial Fund of The Pittsburgh Foundation (Drs. Fagiolini, Kupfer, Cook, Scott, Novick and Frank). Dr. Fagiolini is on the advisory board and a consultant to Pfizer Inc, and Bristol Myers Squibb, and is on the speaker bureau of Bristol Myers Squibb, Eli Lilly Italy, Pfizer Inc, and Shire. Dr. Frank is on the advisory board of Pfizer Inc. and Eli Lilly & Company, and is a consultant to Pfizer Italia and Servier Amerique. Dr. Kupfer is on the advisory board of Pfizer, Inc., Forest Pharmaceuticals, Inc., and Solvay

  5. EMSO ERIC - Ocean Consortium Facility for Europe and the World

    NASA Astrophysics Data System (ADS)

    Best, Mairi

    2017-04-01

    EMSO is forging ahead through the next challenge in Earth-Ocean Science: How to co-ordinate ocean data acquisition, analysis and response across provincial, national, regional, and global scales. EMSO provides power, communications, sensors, and data infrastructure for continuous, high resolution, real-time, interactive ocean observations across a truly multi- and interdisciplinary range of research areas including biology, geology, chemistry, physics, engineering, and computer science; from polar to tropical environments, through the water column down to the abyss. 11 deep sea and 4 shallow nodes span from Arctic through the Atlantic and Mediterranean, to the Black Sea. The EMSO Preparatory Phase (FP7) project led to the Interim phase (involving 13 countries) of forming the legal entity: the EMSO European Research Infrastructure Consortium (EMSO-ERIC)-officially created by the EC in 2016. The open user community, originally developed through ESONET (European Seafloor Observatory NETwork), follows on scientific community planning contributions of the ESONET-NoE (FP6) project. Further progress made through the FixO3 project (FP7) also contributes to this shared infrastructure. Coordination among nodes is being strengthened through the EMSOdev project (H2020) which is producing the EMSO Generic Instrument Module (EGIM) - standardised observations of temperature, pressure, salinity, dissolved oxygen, turbidity, chlorophyll fluorescence, currents, passive acoustics, pH, pCO2, and nutrients. Early installations are now being upgraded; in October 2015 EMSO-France deployed a second cable and junction box serving the Ligurian Sea Node in order to monitor slope stability offshore Nice; in 2016 the EMSO Azores Node receives a major upgrade that will double its observing capacity; for EMSO-Italia the Capo Passero site is being installed and the Catania site is being upgraded. EMSOLINK will continue the expansion work. EMSO is a key player in international coordination

  6. The EMSO ERIC Consortium: A Multidisciplinary, Multinational Organisation of Ocean Observatories.

    NASA Astrophysics Data System (ADS)

    Best, M.

    2016-12-01

    EMSO is forging ahead through the next challenge in Earth-Ocean Science: How to co-ordinate ocean data acquisition, analysis and response across provincial, national, regional, and global scales. EMSO provides power, communications, sensors, and data infrastructure for continuous, high resolution, real-time, interactive ocean observations across a truly multi- and interdisciplinary range of research areas including biology, geology, chemistry, physics, engineering, and computer science; from polar to tropical environments, through the water column down to the abyss. 11 deep sea and 4 shallow nodes span from Arctic through the Atlantic and Mediterranean, to the Black Sea. The EMSO Preparatory Phase (FP7) project led to the Interim phase (involving 13 countries) of forming the legal entity: the EMSO European Research Infrastructure Consortium (EMSO-ERIC)-officially created by the EC in 2016. The open user community through ESONET-Vi (European Seafloor Observatory NETwork - The Vision), follows on scientific community planning contributions of the ESONET-NoE (FP6) project. Further progress made through the FixO3 project (FP7) also contributes to this shared infrastructure. Coordination among nodes is being strengthened through the EMSOdev project (H2020) which is producing the EMSO Generic Instrument Module (EGIM) - standardised observations of temperature, pressure, salinity, dissolved oxygen, turbidity, chlorophyll fluorescence, currents, passive acoustics, pH, pCO2, and nutrients. Early installations are now being upgraded; in October 2015 EMSO-France deployed a second cable and junction box serving the Ligurian Sea Node in order to monitor slope stability offshore Nice; in 2016 the EMSO Azores Node receives a major upgrade that will double its observing capacity; for EMSO-Italia the Capo Passero site is being installed and the Catania site is being upgraded. EMSO is a key player in international coordination projects such as CoopEUS/Coop+, ENVRI/ENVRIplus, GOOS

  7. Relationship between landslide processes and land use-land cover changes in mountain regions: footprint identification approach.

    NASA Astrophysics Data System (ADS)

    Petitta, Marcello; Pregnolato, Marco; Pedoth, Lydia; Schneiderbauer, Stefan

    2015-04-01

    The present investigation aims to better understand the relationship between landslide events and land use-land cover (LULC) changes. Starting from the approach presented last year at national level ("In search of a footprint: an investigation about the potentiality of large datasets and territorial analysis in disaster and resilience research", Geophysical Research Abstracts Vol. 16, EGU2014-11253, 2014) we focused our study at regional scale considering South Tyrol, a mountain region in Italy near the Austrian border. Based on the concept exploited in the previous work, in which a disaster footprint was shown using land features and changes maps, in this study we start from the hypothesis that LULC can have a role in activation of landslides events. In this study, we used LULC data from CORINE and from a regional map called REAKART and we used the Italian national database IFFI (Inventario Fenomeni Franosi in Italia, Italian inventory of landslides) from which it is possible to select the landslides present in the national inventory together with other vector layers (the urban areas - Corine Land Cover 2000, the roads and railways, the administrative boundaries, the drainage system) and raster layers (the digital terrain model, digital orthophoto TerraItaly it2000, Landsat satellite images and IGM topographic map). Moreover it's possible to obtain information on the most important parameters of landslides, view documents, photos and videos. For South Tyrol, the IFFI database is updated in real time. In our investigation we analyzed: 1) LULC from CORINE and from REAKART, 2) landslides occurred nearby a border of two different LULC classes, 3) landslides occurred in a location in which a change in LULC classification in observed in time, 4) landslides occurred nearby road and railroad. Using classification methods and statistical approaches we investigated relationship between the LULC and the landslides events. The results confirm that specific LULC classes are

  8. The contribute of DInSAR techniques to landslide hazard evaluation in mountain and hilly regions: a case study from Agno Valley (North-Eastern Italian Alps)

    NASA Astrophysics Data System (ADS)

    De Agostini, A.; Floris, M.; Pasquali, P.; Barbieri, M.; Cantone, A.; Riccardi, P.; Stevan, G.; Genevois, R.

    2012-04-01

    In the last twenty years, Differential Synthetic Aperture Radar Interferometry (DInSAR) techniques have been widely used to investigate geological processes, such as subsidence, earthquakes and landslides, through the evaluation of earth surface displacements caused by these processes. In the study of mass movements, contribution of interferometry can be limited due to the acquisition geometry of RADAR images and the rough morphology of mountain and hilly regions which represent typical landslide-prone areas. In this study, the advanced DInSAR techniques (i.e. Small Baseline Subset and Persistent Scatterers techniques), available in SARscape software, are used. These methods involve the use of multiple acquisitions stacks (large SAR temporal series) allowing improvements and refinements in landslide identification, characterization and hazard evaluation at the basin scale. Potential and limits of above mentioned techniques are outlined and discussed. The study area is the Agno Valley, located in the North-Eastern sector of Italian Alps and included in the Vicenza Province (Veneto Region, Italy). This area and the entire Vicenza Province were hit by an exceptional rainfall event on November 2010 that triggered more than 500 slope instabilities. The main aim of the work is to verify if spatial information available before the rainfall event, including ERS and ENVISAT RADAR data from 1992 to 2010, were able to predict the landslides occurred in the study area, in order to implement an effectiveness forecasting model. In the first step of the work a susceptibility analysis is carried out using landslide dataset from the IFFI project (Inventario Fenomeni Franosi in Italia, Landslide Italian Inventory) and related predisposing factors, which consist of morphometric (elevation, slope, aspect and curvature) and non-morphometric (land use, distance of roads and distance of river) factors available from the Veneto Region spatial database. Then, to test the prediction, the

  9. Non-Susceptible Landslide Areas in Italy and in the Mediterranean Region

    NASA Astrophysics Data System (ADS)

    Alvioli, Massimiliano; Ardizzone, Francesca; Guzzetti, Fausto; Marchesini, Ivan; Rossi, Mauro

    2014-05-01

    Landslide susceptibility is the likelihood of a landslide occurring in a given area. Over the past three decades, researchers, and planning and environmental organisations have worked to assess landslide susceptibility at different geographical scales, and to produce maps portraying landslide susceptibility zonation. Little effort was made to determine where landslides are not expected, where susceptibility is null, or negligible. This is surprising because planners and decision makers are also interesting in knowing where landslides are not foreseen, or cannot occur in an area. We propose a method for the definition of non-susceptible landslide areas, at the synoptic scale. We applied the method in Italy and to the territory surrounding the Mediterranean Sea and we produced two synoptic-scale maps showing areas where landslides are not expected in Italy and in the Mediterranean area. To construct the method we used digital terrain elevation and landslide information. The digital terrain consisted in the 3-arc-second SRTM DEM, the landslide information was obtained for 13 areas in Italy where landslide inventory maps were available to us. We tested three different models to determine the non-susceptible landslide areas, including a linear model (LR), a quantile linear model (QLR), and a quantile non-linear model (QNL). Model performances have been evaluated using independent landslide information represented by the Italian Landslide Inventory (Inventario Fenomeni Franosi in Italia - IFFI). Best results were obtained using the QNL model. The corresponding zonation of non- susceptible landslide areas was intersected in a GIS with geographical census data for Italy. The results show that the 57.5% of the population of Italy (in 2001) was located in areas where landslide susceptibility was expected to be null or negligible, while the remaining 42.5% in areas where some landslide susceptibility was significant or not negligible. We applied the QNL model to the

  10. Determination of the Attenuation Equation of Strong Motion in the Michoacán State

    NASA Astrophysics Data System (ADS)

    Vazquez Rosas, R.; Aguirre, J.; Ramirez-Guzman, L.

    2014-12-01

    Several attenuation relationships have been developed to Mexico, mostly after the September 19, 1985 earthquake which has meant a watershed in the development of Mexican seismological engineering. Since 1985, the number of seismic stations has increased significantly especially between the Coast of Guerrero and Mexico City because of the large amplifications that have acurrect on lake zone and hard ground sites in Mexico City. Some studies have analyzed how the seismic waves are attenuated or amplified from the Pacific coast towards the continent. The attenuation relationship used for seismic hazard assessment in Mexico is due to Ordaz (1989) this was obtained from data from the Guerrero acceleration network. Another recent study is that conducted by (Garcia et al., 2005) with recent data from the Guerrero acceleration network considering intraplate earthquakes. It is important to note that all these relations cover to only part of the Mexican subduction zone, and for some types of seismic sources it may be not suitable to study the earthquake risk in other regions of Mexico. For this work we consider the state of Michoacán, because it has one of the most important seismogenic zones in Mexico. Within the state there are three different kinds of seismic sources: and volcanic tectonic earthquakes and those caused by local faults in the region. Then it is a vital issue to study the seismic wave propagation within the state. We installed a temporary network with 9 accelerographic stations, located at Faro de Brucerías, Aguililla, Apatzingán, Taretán, Uruapan, Nueva Italia Pátzcuaro, Morelia and Maravatío, Michoacán. The stations formed a perpendicular line to the coast, with a total length of 366 km, the distance between stations varies from 60 to 80 km. Among the total seismic events recorded, we selected 7 seismic events located in the Michoacán coastline, from 4.1 to 5.1 Mw. With those records, Q quality factor (107.215 f 0.74) was calculated for frequencies

  11. The application of observational data in translational medicine: analyzing tobacco-use behaviors of adolescents

    PubMed Central

    2012-01-01

    Background Translational Medicine focuses on “bench to bedside”, converting experimental results into clinical use. The “bedside to bench” transition remains challenging, requiring clinicians to define true clinical need for laboratory study. In this study, we show how observational data (an eleven-year data survey program on adolescent smoking behaviours), can identify knowledge gaps and research questions leading directly to clinical implementation and improved health care. We studied gender-specific trends (2000–2010) in Italian students to evaluate the specific impact of various anti-smoking programs, including evaluation of perceptions of access to cigarettes and health risk. Methods The study used, ESPAD-Italia® (European School Survey Project on Alcohol and other Drugs), is a nationally representative sample of high-school students. The permutation test for joinpoint regression was used to calculate the annual percent change in smoking. Changes in smoking habits by age, perceived availability and risk over a 11-year period were tested using a gender-specific logistic model and a multinomial model. Results Gender-stratified analysis showed 1) decrease of lifetime prevalence, then stabilization (both genders); 2) decrease in last month and occasional use (both genders); 3) reduction of moderate use (females); 4) no significant change in moderate use (males) and in heavy use (both genders). Perceived availability positively associates with prevalence, while perceived risk negatively associates, but interact with different effects depending on smoking patterns. In addition, government implementation of public policies concerning access to tobacco products in this age group during this period presented a unique background to examine their specific impact on behaviours. Conclusion Large observational databases are a rich resource in support of translational research. From these observations, key clinically relevant issues can be identified and form the

  12. Education and guidance to the civil protection culture: insights and first results from the SicuraMente project

    NASA Astrophysics Data System (ADS)

    Romeo, Saverio; Benvenuti, Eugenio; Calabrese, Danilo; Galluccio, Dario Giuseppe; Tocci, Mauro

    2017-04-01

    To gain awareness on natural hazards social and educational initiatives are required, aimed at promoting a civil protection culture able to guide towards conscious and correct behavior. People, well-informed about risks in their territory, are safer citizens. In this perspective, it is important that the learning environments, such as schools and universities, play a key role on promoting dialogue and interactions among institutions, becoming a useful resource for the local community. In this framework, the present work describes an experimental project, called SicuraMente, started 2 years ago, about safety and civil protection culture coordinated by LARES Italia, a national civil protection association. This ongoing project, that involves high school and university students, is a training course that teaches skills and grants its participants specific toolset to increase the civic awareness and personal knowledge on actions to take in specific emergency situations. SicuraMente is a multi-hazard project, concerning several natural phenomena such as earthquake, flood, landslide, fire and extreme meteorological events. Each topic is discussed with a global approach starting from the scientific knowledge of the phenomenon, with a final discussion on the best practices about disaster prevention and preparedness. Additionally, in order to encourage the interest of students, 4 contexts are taken in example (home, school, city, society) with special case study sessions of each, with open discussion and debate. The project's activities are conducted on two levels: peer education lessons with "learning by doing" approach (e.g. simulation-based learning) under the coordination of LARES volunteers, and a further training stage at home in e-learning environment (www.sicuramentelab.it). In the first year of the project, 669 students from 9 schools of Regione Umbria (Central Italy) were involved. Thanks to the fundamental support of the volunteers of LARES association, 543

  13. A multiregional Italian cohort of 24-hour urine metabolic evaluation in renal stone formers.

    PubMed

    Esperto, Francesco; Marangella, Martino; Trinchieri, Alberto; Petrarulo, Michele; Miano, Roberto

    2017-09-07

    Nephrolithiasis is a common condition with several studies documenting an increased prevalence over the past four decades. EAU and AUA guidelines recommend 24-hour urine metabolic evaluation in high-risk stone formers. Aim of this study is to retrospectively evaluate the first three years of experience with Lithotest® (Biohealth Italia Srl, Turin, Italy) through the analysis of demographic, clinical and biochemical data collected from a large cohort of patients with kidney stones. We retrospectively analysed data from the LithoCenter database, including data from outpatient consultations, between January 2007 and December 2009 from all over Italy. Lithotest® was performed through a 24-h urine collection and included measurements of urine volume and pH, 24-h excretion of creatinine as well as main cations and anions, including calcium, magnesium sodium potassium, ammonium, uric acid, oxalate, citrate, phosphate, inorganic sulphate and chloride. Urine state of saturation for calcium oxalate (ßCaOx), calcium hydrogen phosphate or brushite (ßbsh) and uric acid (ßUA) were also calculated by means of the computer program Lithorisk. Brand's test for cystinuria was also carried out. Statistical analysis was performed using the S-PSS 22.0 software. The number of patients with data available for analysis was 435, 236 males (54%) and 199 females (46%). Complete 24-h urine measurements were available for all 435 patients. Compared to men, women had significantly lower values for creatinine, irate, oxalate, phosphate, sodium, potassium, magnesium and chloride excretion, whereas 24-hour pH and citrate excretion were higher. No significant differences were found for the other examined variables. ßCaOx and ßUA were significantly higher in men than women, whereas no significant difference was found for ßbsh. There was a direct relationship between calcium and sodium urine excretion. Excessive sodium excretion was recorded in 191 patients (44%) and low urine volumes in 201

  14. Geodetic Leveling Data In Northern-central Apennines (italy): Vertical Geodetic Strain Versus Seismicity and Seismogenic Structures

    NASA Astrophysics Data System (ADS)

    D'Anastasio, E.; de Martini, P. M.; Selvaggi, G.; Pantosti, D.; Marchioni, A.

    For over 120 years the Istituto Geografico Militare d'Italia (IGM) has repeatedly mea- sured the elevation of selected routes running along and across the Italian peninsula. Some of these routes have been measured three times during a time span of over a century, thus yielding a fundamental contribution to the quantification of vertical tec- tonic strains. Through the years, the main national first order leveling lines, for which the measurement accuracy is particularly good, have captured long-wavelength trends, interpreted as regional uplift or doming of volcanic areas, together with coseismic el- evation changes associated with large earthquakes. The scope of this contribution is to present our methodology in the analysis of the regional geodetic signal and to stimu- late the discussion on its possible relations with the instrumental/historical seismicity and with known major seismogenic structures. As a first step of this project we have studied in detail four transects across the northern-central Apennines, using seven lev- eling lines for a total length of about 750 km. For each route we have at least a 20 years-long record and a benchmark's density higher than 0.3/km. The most important errors, both random and systematic, will be discussed together with IGM's standard for first order leveling lines and with the probable total error we adopted as a good measure of the overall uncertainty. Being very arduous to determine absolute heights for any benchmark in Italy, we decided to adopt a procedure involving relative eleva- tion changes, where the westernmost point (on the Thyrrenian side) of each transect is assumed stable. The observed elevation changes stand significantly above the detec- tion threshold of the geodetic instruments and show regional long-wavelength signal. Along three of the four transects, a relative maximum elevation change rate of about 1 mm/yr has been observed. A preliminary comparison of the geodetic signals with instrumental and

  15. Systematic recover of long high-resolution rainfall time series recorded by pluviographs during the 20th century.

    NASA Astrophysics Data System (ADS)

    Delitala, Alessandro M. S.; Deidda, Roberto; Mascaro, Giuseppe; Piga, Enrico; Querzoli, Giorgio

    2010-05-01

    During most of the 20th century, precipitation has been continuously measured by means of the so-called "pluviographs", i.e. rain gauges including a mechanical apparatus for continuously recording the depth of water from precipitation on specific strip charts, usually on a weekly basis. The signal recorded on such strips was visually examined by trained personnel on a regular basis, in order to extract the daily precipitation totals and the maximum precipitation intensities over short periods (from a few minutes to hours). The rest of the high-resolution information contained in the signal was usually not extracted, except for specific cases. A systematic recovering of the entire information at high temporal resolution contained in these precipitation signals would provide a fundamental database to improve the characterization of historical rainfall climatology during the previous century. The Department of Land Engineering of the University of Cagliari has recently developed and tested an automatic software, based on image analysis techniques, which is able to acquire the scanned images of the pluviograph strip charts, to automatically digitise the signal and to produce a digital database of continuous precipitation records at the highest possible temporal resolution, i.e. 5 to 10 minutes. Along with that, a significant amount of daily precipitation totals from the late 19th and the 20th century, either elaborated from pluviograph strip charts or simply derived from bucket rain gauges, still exists in paper form, but it has never been digitalized. Within a project partly-funded by the Operational Programme of the European Union "Italia-Francia Marittimo", the Regional Environmental Protection Agency of Sardinia and the University of Cagliari will recover both the high-resolution rainfall signals and the older time series of daily totals recorded by a large number of pluviographs belonging to the historical monitoring networks of the island of Sardinia. Such data

  16. Present activity and seismogenic potential of a low-angle normal fault system (Città di Castello, Italy): Constraints from surface geology, seismic reflection data and seismicity

    NASA Astrophysics Data System (ADS)

    Brozzetti, Francesco; Boncio, Paolo; Lavecchia, Giusy; Pace, Bruno

    2009-01-01

    We present new constraints on an active low-angle normal fault system in the Città di Castello-Sansepolcro basin (CSB) of the northern Apennines of Italy. New field data from the geological survey of the Carta Geologica d' Italia (CARG project) define the surface geometry of the normal fault system and lead to an interpretation of the CROP 03 deep-crust seismic reflection profile (Castiglion Fiorentino-Urbania segment), with particular attention paid to the geometry of the Plio-Quaternary extensional structures. Surface and sub-surface geological data are integrated with instrumental and historical seismicity in order to define the seismotectonics of the area. Low-angle east-dipping reflectors are the seismic expression of the well-known Altotiberina Fault (AF), a regional extensional detachment on which both east- and west-dipping high-angle faults, bounding the CSB, sole out. The AF breakaway zone is located ˜ 10 km west of the CSB. Within the extensional allochthon, synthetic east-dipping planes prevail. Displacement along the AF is ˜ 4.5 km, which agrees with the cumulative offset due to its synthetic splays. The evolution of the CSB has mainly been controlled by the east-dipping fault system, at least since Early Pleistocene time; this system is still active and responsible for the seismicity of the area. A low level of seismic activity was recorded instrumentally within the CSB, but several damaging earthquakes have occurred in historical times. The instrumental seismicity and the intensity data points of the largest historical earthquakes (5 events with maximum MCS intensity of IX to IX-X) allow us to propose two main seismogenic structures: the Monte Santa Maria Tiberina (Mmax = 5.9) and Città di Castello (Mmax up to 6.5) normal faults. Both are synthetic splays of the AF detachment, dipping to the NE at moderate (45-50°) to low (25-30°) angles and cutting the upper crust up to the surface. This study suggests that low-angle normal faults (at least

  17. PRIMA Platform capability for satellite missions in LEO and MEO (SAR, Optical, GNSS, TLC, etc.)

    NASA Astrophysics Data System (ADS)

    Logue, T.; L'Abbate, M.

    2016-12-01

    PRIMA (Piattaforma Riconfigurabile Italiana Multi Applicativa) is a multi-mission 3-axis stabilized Platform developed by Thales Alenia Space Italia under ASI contract.PRIMA is designed to operate for a wide variety of applications from LEO, MEO up to GEO and for different classes of satellites Platform Family. It has an extensive heritage in flight heritage (LEO and MEO Satellites already fully operational) in which it has successfully demonstrated the flexibility of use, low management costs and the ability to adapt to changing operational conditions.The flexibility and modularity of PRIMA provides unique capability to satisfy different Payload design and mission requirements, thanks to the utilization of recurrent adaptable modules (Service Module-SVM, Propulsion Module-PPM, Payload Module-PLM) to obtain mission dependent configuration. PRIMA product line development is continuously progressing, and is based on state of art technology, modular architecture and an Integrated Avionics. The aim is to maintain and extent multi-mission capabilities to operate in different environments (LEO to GEO) with different payloads (SAR, Optical, GNSS, TLC, etc.). The design is compatible with a wide range of European and US equipment suppliers, thus maximising cooperation opportunity. Evolution activities are mainly focused on the following areas: Structure: to enable Spacecraft configurations for multiple launch; Thermal Control: to guarantee thermal limits for new missions, more demanding in terms of environment and payload; Electrical: to cope with higher power demand (e.g. electrical propulsion, wide range of payloads, etc.) considering orbital environment (e.g. lighting condition); Avionics : AOCS solutions optimized on mission (LEO observation driven by agility and pointing, agility not a driver for GEO). Use of sensors and actuators tailored for specific mission and related environments. Optimised Propulsion control. Data Handling, SW and FDIR mission customization

  18. Enabling technologies for space exploration systems: The STEPS project results and perspectives

    NASA Astrophysics Data System (ADS)

    Messidoro, Piero; Perino, Maria Antonietta; Boggiatto, Dario

    2013-05-01

    The project STEPS (Sistemi e Tecnologie per l'EsPlorazione Spaziale) is a joint development of technologies and systems for Space Exploration supported by Regione Piemonte, the European Regional Development Fund (E.R.D.F.) 2007-2013, Thales Alenia Space Italia (TAS-I), SMEs, Universities and public Research Centres belonging to the network "Comitato Distretto Aerospaziale del Piemonte" the Piedmont Aerospace District (PAD) in Italy. The project first part terminated in May 2012 with a final demonstration event that summarizes the technological results of research activities carried-out during a period the three years and half. The project developed virtual and hardware demonstrators for a range of technologies for the descent, soft landing and surface mobility of robotic and manned equipment for Moon and Mars exploration. The two key hardware demonstrators—a Mars Lander and a Lunar Rover—fit in a context of international cooperation for the exploration of Moon and Mars, as envisaged by Space Agencies worldwide. The STEPS project included also the development and utilization of a system of laboratories equipped for technology validation, teleoperations, concurrent design environments, and virtual reality simulation of the Exploration Systems in typical Moon and Mars environments. This paper presents the reached results in several technology domains like: vision-based GNC for the last portion of Mars Entry, Descent and Landing sequence, Hazard avoidance and complete spacecraft autonomy; Autonomous Rover Navigation, based on the determination of the terrain morphology by a stereo camera; Mobility and Mechanisms providing an Integrated Ground Mobility System, Rendezvous and Docking equipment, and protection from Environment effects; innovative Structures such as Inflatable, Smart and Multifunction Structures, an Active Shock Absorber for safe landing, balance restoring and walking; Composite materials Modelling and Monitoring; Human-machine interface features of a

  19. Historic (1940 to present) changes in Lillooet River planform (BC, Canada)

    NASA Astrophysics Data System (ADS)

    Zei, Caterina

    2017-04-01

    Historic (1940 to present) changes in Lillooet River planform (BC, Canada) Zei C.*, Giardino M.*, Perotti L.*, Roberti G.***, **Ward B.C.**, Clague J.J.** *Department of Earth Sciences, Geositlab, Università degli Studi di Torino, Torino, Italia; **Department of Earth Sciences, Simon Fraser University, Burnaby, British Columbia, Canada ***Université Blaise Pascal - Laboratoire Magmas et Volcans Clermont-Ferrand, France We conducted a geomorphological study of changes in the planform of Lillooet River (Coast Mountain, British Columbia, Canada) over the past 75 years. The study involved identification and interpretations of channel changes in the reach of the river between Mount Meager (the source of the landslide) and Pemberton Meadows. Lillooet River flows about 95 km southeast from its headwaters at Lillooet Glacier to Lillooet Lake near Pemberton, the largest community in the valley. Between the mouth of Meager Creek and Pemberton Meadows, the river is unregulated and has a braided planform resulting from the very high delivery of sediment due to frequent landslides and debris flows sourced on the Mount Meager volcanic complex. Below Pemberton Meadows, the river occupies a single channel confined between dikes. A rich archive of historical vertical aerial photographs exists for the study area, In addition, a high-resolution digital elevation model was produced from LiDAR data acquired in 2015. We processed each set of photos dating back to 1940 with the software Agisoft Photoscan to produce high resolution orthophotos. Analysis of these datasets, complemented with field investigation, showed that the river channel in the braided reach shifted laterally up to 550 m between 1981 and 2010; likely caused in part by five floods with peak discharges of more than 800 m^3/s and four landslides on the flanks of Mount Meager massif with volumes up to 13 x 106 m^3. Channel avulsions were probably triggered by accumulation of in-channel rafts of coarse woody debris and are

  20. Rheticus Displacement: an Automatic Geo-Information Service Platform for Ground Instabilities Detection and Monitoring

    NASA Astrophysics Data System (ADS)

    Chiaradia, M. T.; Samarelli, S.; Agrimano, L.; Lorusso, A. P.; Nutricato, R.; Nitti, D. O.; Morea, A.; Tijani, K.

    2016-12-01

    and descending passes. ACK: Study carried out in the framework of the FAST4MAP project and co-funded by the Italian Space Agency (Contract n. 2015-020-R.0). Sentinel-1A products provided by ESA. CSK® Products, ASI, provided by ASI under a license to use. Rheticus® is a registered trademark of Planetek Italia srl.

  1. Randomized noninferiority field trial comparing 2 first-generation cephalosporin products at dry off in quarters receiving an internal teat sealant in dairy cows.

    PubMed

    Ospina, P A; Rota, N; Locatelli, C; Colombo, L; Pollera, C; Giacinti, G; Bronzo, V; Casula, A; Arpinelli, A; Brossette, V; Facchi, M; Patelli, A; Ruggeri, A; Barberio, A; Potenza, G; Nydam, D V; Moroni, P

    2016-08-01

    The study objective was to compare 2 commercial dry cow mastitis products at the quarter level, with concurrent internal teat sealant application, evaluating the cure risk difference, odds of a cure, odds of a new intramammary infection (NIMI) during the dry period, and risk for a clinical mastitis (CM) case between calving and 60d in milk (DIM). A total of 590 cows (2,360 quarters) from 8 commercial dairy herds in Italy were enrolled and randomized to 1 of the 2 treatments at dry off: Cefovet A (CF; 250mg of cephazoline; Merial Italia SpA, Milan, Italy), and Cepravin (CP; 250mg of cephalonium dehydrate MSD Animal Health Srl, Segrate, Italy). Quarter milk samples were collected before dry cow therapy treatment at dry off, 2 to 9 DIM, and 10 to 17 DIM. Quarter milk samples from CM cases were collected during the first 60 DIM. Noninferiority analysis was used to evaluate the effect of treatment on the risk difference of a bacteriological cure during the dry period, the primary outcome. The odds of cure, developing a NIMI during the dry period, and the risk of a CM event within 60 DIM were evaluated with multivariable logistic regression and hazard analysis, respectively. The overall crude quarter-level prevalence of NIMI at dry off was 15.3%. The most common pathogen isolated from milk samples at dry-off was coagulase-negative staphylococci. Noninferiority analysis showed no effect of treatment on the risk difference for a cure between dry off and both postpartum samples, difference was 0.013. The least squares means from the multivariable model evaluating the odds of cure was 94% for CF and 95%for CP. We observed no effect of treatment on the odds for the presence of a NIMI at 2 to 9 DIM (least squares means: CF=0.09 and CP=0.07), nor did we note a difference in risk of experiencing a CM event between calving and 60 DIM (hazard ratio=0.8). In conclusion, no difference was observed between the 2 products evaluated when assessing the aforementioned outcomes in

  2. [HSV-1 and HSV-2 seropositivity rates in pregnant women admitted to Izmir Ataturk Research and Training Hospital, Turkey].

    PubMed

    Ozdemir, Rahim; Er, Hakan; Baran, Nurten; Vural, Ahmet; Demirci, Mustafa

    2009-10-01

    In this study, the seropositivity rates of herpes simplex virus (HSV) types 1 and 2, and their distribution according to the age groups in the sera of asymptomatic pregnant women who were admitted to Gynecology and Obstetrics clinics of Izmir Ataturk Research and Training Hospital for routine control, were investigated. IgG and IgM antibodies specific for HSV-1 and HSV-2 were screened by commercial ELISA kits (RADIM SpA-Pomezia, Italia). Total IgG seropositivity rates for HSV-1 and HSV-2 were found as 94.7% (108/114) and 8.2% (13/158), while IgM seropositivities were 0 (0/114) and 1.4% (2/148), respectively. The distribution of HSV-1 and HSV-2 IgG seropositivity rates according to the age groups were as follows; 100% (8/8) and 10% (1/10) in 18-20; 92.9% (26/28) and 13.9% (5/36) in 21-25; 93.3% (42/45) and 3% (2/66) in 26-30; 96.6% (28/29) and 8.3% (3/36) in 31-35 and 100% (4/4) and 20% (2/10) in 36-40 years age groups, respectively. HSV-2 IgM antibodies were positive only in 21-25 years age group (2/35; 5.7%). The difference between seropositivity rates of HSV-1 IgG and HSV-2 IgG were found statistically significant (p = 0.000, p < 0.05); whereas the differences between both HSV-1 IgG and IgM and HSV-2 IgG and IgM seropositivity rates in the age groups didn't display statistical significance (p = 0.872, p> 0.05; p = 0.217, p> 0.05). The aim of this letter was to contribute to the seroepidemiological data of HSV prevalance in pregnant women in our region.

  3. PUS Services Software Building Block Automatic Generation for Space Missions

    NASA Astrophysics Data System (ADS)

    Candia, S.; Sgaramella, F.; Mele, G.

    2008-08-01

    The Packet Utilization Standard (PUS) has been specified by the European Committee for Space Standardization (ECSS) and issued as ECSS-E-70-41A to define the application-level interface between Ground Segments and Space Segments. The ECSS-E- 70-41A complements the ECSS-E-50 and the Consultative Committee for Space Data Systems (CCSDS) recommendations for packet telemetry and telecommand. The ECSS-E-70-41A characterizes the identified PUS Services from a functional point of view and the ECSS-E-70-31 standard specifies the rules for their mission-specific tailoring. The current on-board software design for a space mission implies the production of several PUS terminals, each providing a specific tailoring of the PUS services. The associated on-board software building blocks are developed independently, leading to very different design choices and implementations even when the mission tailoring requires very similar services (from the Ground operative perspective). In this scenario, the automatic production of the PUS services building blocks for a mission would be a way to optimize the overall mission economy and improve the robusteness and reliability of the on-board software and of the Ground-Space interactions. This paper presents the Space Software Italia (SSI) activities for the development of an integrated environment to support: the PUS services tailoring activity for a specific mission. the mission-specific PUS services configuration. the generation the UML model of the software building block implementing the mission-specific PUS services and the related source code, support documentation (software requirements, software architecture, test plans/procedures, operational manuals), and the TM/TC database. The paper deals with: (a) the project objectives, (b) the tailoring, configuration, and generation process, (c) the description of the environments supporting the process phases, (d) the characterization of the meta-model used for the generation, (e) the

  4. The Central and Eastern European Earthquake Research Network - CE3RN

    NASA Astrophysics Data System (ADS)

    Bragato, Pier Luigi; Costa, Giovanni; Gallo, Antonella; Gosar, Andrej; Horn, Nikolaus; Lenhardt, Wolfgang; Mucciarelli, Marco; Pesaresi, Damiano; Steiner, Rudolf; Suhadolc, Peter; Tiberi, Lara; Živčić, Mladen; Zoppé, Giuliana

    2014-05-01

    The region of the Central and Eastern Europe is an area characterised by a relatively high seismicity. The active seismogenic structures and the related potentially destructive events are located in the proximity of the political boundaries between several countries existing in the area. An example is the seismic region between the NE Italy (FVG, Trentino-Alto Adige and Veneto), Austria (Tyrol, Carinthia) and Slovenia. So when a destructive earthquake occurs in the area, all the three countries are involved. In the year 2001 the Agencija Republike Slovenije za Okolje (ARSO) in Slovenia, the Department of Mathematics and Geoscience of the University of Trieste (DMG), the OGS (Istituto Nazionale di Oceanografia e di Geofisica Sperimentale) in Italy and the Zentralanstalt für Meteorologie und Geodynamik (ZAMG) in Austria signed an agreement for the real-time seismological data exchange in the Southeastern Alps region. Soon after the Interreg IIIa Italia-Austria projects "Trans-National Seismological Networks in the South-Eastern Alps" and "FASTLINK" started. The main goal of these projects was the creation of a transfrontier network for the common seismic monitoring of the region for scientific and civil defense purposes. During these years the high quality data recorded by the transfrontier network has been used, by the involved institutions, for their scientific research, for institutional activities and for the civil defense services. Several common international projects have been realized with success. The instrumentation has been continuously upgraded, the installations quality improved as well as the data transmission efficiency. In the 2013 ARSO, DMG, OGS and ZAMG decided to name the cooperative network "Central and Eastern European Earthquake Research Network - CE3RN". The national/regional seismic networks actually involved in the CE3RN network are: • Austrian national BB network (ZAMG - OE) • Friuli Veneto SP network (OGS - FV) • Friuli VG

  5. 2012-2025 Roadmap of I.R.Iran’s Disaster Health Management

    PubMed Central

    Ardalan, Ali; Rajaei, Mohammad Hossein; Masoumi, Gholamreza; Azin, Ali; Zonoobi, Vahid; Sarvar, Mohammad; Vaskoei Eshkevari, khorshid; Ahmadnezhad, Elham; Jafari, Gelareh

    2012-01-01

    with a list of strategies and activities to be considered in operational planning and actions. However, a dynamic process of evaluation and revision is required to ensure that Iran’s health system goals are met by 2025. Address for correspondence: Ali Ardalan, No. 78, Italia Ave, Department of Disaster and Emergency Health, National Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran. Email: aardalan@gmail.com or aardalan@tums.ac.ir Citation: Ardalan A, Rajaei MH, Masoumi G, Azin A, Zonoobi V, Sarvar M, Vaskoei Eshkevari K, Ahmadnezhad E, Jafari G. 2012-2025 Roadmap of I.R.Iran’s Disaster Health Management. PLoS Currents Disasters. 2012 Jul 16 PMID:22953239

  6. Are cannabis prevalence estimates comparable across countries and regions? A cross-cultural validation using search engine query data.

    PubMed

    Steppan, Martin; Kraus, Ludwig; Piontek, Daniela; Siciliano, Valeria

    2013-01-01

    Prevalence estimation of cannabis use is usually based on self-report data. Although there is evidence on the reliability of this data source, its cross-cultural validity is still a major concern. External objective criteria are needed for this purpose. In this study, cannabis-related search engine query data are used as an external criterion. Data on cannabis use were taken from the 2007 European School Survey Project on Alcohol and Other Drugs (ESPAD). Provincial data came from three Italian nation-wide studies using the same methodology (2006-2008; ESPAD-Italia). Information on cannabis-related search engine query data was based on Google search volume indices (GSI). (1) Reliability analysis was conducted for GSI. (2) Latent measurement models of "true" cannabis prevalence were tested using perceived availability, web-based cannabis searches and self-reported prevalence as indicators. (3) Structure models were set up to test the influences of response tendencies and geographical position (latitude, longitude). In order to test the stability of the models, analyses were conducted on country level (Europe, US) and on provincial level in Italy. Cannabis-related GSI were found to be highly reliable and constant over time. The overall measurement model was highly significant in both data sets. On country level, no significant effects of response bias indicators and geographical position on perceived availability, web-based cannabis searches and self-reported prevalence were found. On provincial level, latitude had a significant positive effect on availability indicating that perceived availability of cannabis in northern Italy was higher than expected from the other indicators. Although GSI showed weaker associations with cannabis use than perceived availability, the findings underline the external validity and usefulness of search engine query data as external criteria. The findings suggest an acceptable relative comparability of national (provincial) prevalence

  7. Data Model for Multi Hazard Risk Assessment Spatial Support Decision System

    NASA Astrophysics Data System (ADS)

    Andrejchenko, Vera; Bakker, Wim; van Westen, Cees

    2014-05-01

    The goal of the CHANGES Spatial Decision Support System is to support end-users in making decisions related to risk reduction measures for areas at risk from multiple hydro-meteorological hazards. The crucial parts in the design of the system are the user requirements, the data model, the data storage and management, and the relationships between the objects in the system. The implementation of the data model is carried out entirely with an open source database management system with a spatial extension. The web application is implemented using open source geospatial technologies with PostGIS as the database, Python for scripting, and Geoserver and javascript libraries for visualization and the client-side user-interface. The model can handle information from different study areas (currently, study areas from France, Romania, Italia and Poland are considered). Furthermore, the data model handles information about administrative units, projects accessible by different types of users, user-defined hazard types (floods, snow avalanches, debris flows, etc.), hazard intensity maps of different return periods, spatial probability maps, elements at risk maps (buildings, land parcels, linear features etc.), economic and population vulnerability information dependent on the hazard type and the type of the element at risk, in the form of vulnerability curves. The system has an inbuilt database of vulnerability curves, but users can also add their own ones. Included in the model is the management of a combination of different scenarios (e.g. related to climate change, land use change or population change) and alternatives (possible risk-reduction measures), as well as data-structures for saving the calculated economic or population loss or exposure per element at risk, aggregation of the loss and exposure using the administrative unit maps, and finally, producing the risk maps. The risk data can be used for cost-benefit analysis (CBA) and multi-criteria evaluation (SMCE). The

  8. Aerosol variability over the Mediterranean basin from 2005-2012 POLDER-3/PARASOL and AERONET/PHOTONS measurements

    NASA Astrophysics Data System (ADS)

    Chiapello, Isabelle; Ducos, Fabrice; Dulac, François; Léon, Jean-François; Mallet, Marc; Tanré, Didier; Goloub, Philippe

    2013-04-01

    POLDER-3 (Polarization and Directionnality of the Earth's Reflectances) has been launched on board the PARASOL microsatellite in December 2004. Although the PARASOL orbit has been lowered twice (in September 2009 and in November 2011) compared to the other platforms of the A-Train constellation, POLDER observations continue, providing now more than seven years of innovative retrievals of aerosol properties from space. In this study we focus on analyzing POLDER-3 capabilities to derive both aerosol loads (Total Aerosol Optical Thickness) and size properties (fine and coarse spherical/non-spherical Aerosol Optical Thickness, Angström coefficients) over oceanic surfaces. This analysis, as part of the ChArMEx (the Chemistry-Aerosol Mediterranean Experiment) program, focus on the Mediterranean basin, a region under the influence of a complex mixture of aerosols from different sources. Especially we aim to investigate the respective contributions of (i) pollution aerosols (emitted by industry and urban environments of some European regions or megacities surrounding the basin), (ii) carbonaceous particles (from biomass burning events), (iii) mineral dust exported from arid and semi-arid regions of North Africa. In a first step, our study consists in an analysis of aerosol variability retrieved from AERONET/PHOTONS photometer records from selected sites located in Western part of the Mediterranean basin (i.e., Soust-East of France, Spain, Corsica/Sardinia), as well as central part (i.e., Italia and Lampedusa), and Eastern part (i.e.,Greece and Turkey). These measurements provide a unique characterization of both aerosol load (aerosol optical depth) and properties (size distribution and absorption though single scattering albedo) and their temporal variability over each part of the Mediterranean basin. The second step focus on a regional validation of the PARASOL monthly aerosol products by comparison with these equivalent and selected ground-based AERONET

  9. The influence of genotype, market live weight, transportation, and holding conditions prior to slaughter on broiler breast meat color.

    PubMed

    Bianchi, M; Petracci, M; Cavani, C

    2006-01-01

    A study was conducted to determine the influence of genotype, market live weight, transportation time, holding time, and temperature on broiler breast fillet color under commercial processing in Italy. Color was evaluated using a Minolta Chroma Meter (Minolta Chroma Meter CR-300, Minolta Italia S.p.A., Milano, Italy) on a total of 6,997 broiler breast fillets (Pectoralis major muscle) from 79 different flocks chosen at random during a 6-mo period. The flocks were represented by Ross 508 and Cobb 500 genotypes of both genders, processed at different ages, and subjected to different antemortem conditions during transport and holding. Ross 508 broilers exhibited a lower hue angle (H*) than did Cobb 500 (45.12 vs. 48.52; P < 0.01). With regard to the market live weight of broilers, the heavier birds (>3.3 kg) produced a darker breast meat (L* = 51.67) than did the lighter birds (<3.0 and 3.0 to 3.3 kg; L* = 52.63 and 52.84, respectively) (P < 0.001). The breast fillets from birds transported for the shortest distance (<40 km) exhibited a higher (P < 0.01) breast meat redness (a*; 3.59) when compared with transport distances of 40 to 210 or >210 km (a* = 3.28 and 3.04, respectively). The shortest holding time (<6 h) produced the highest (P < 0.05) L* values (52.84) compared with holding periods of 6 to 9 h and >9 h (L* = 52.12 and 52.04, respectively). Furthermore, an increase of both meat a* and saturation (C*) was observed with the advance in holding time. The holding temperature significantly affected the meat color. Breast fillets from birds held at <12 degrees C was darker (L* = 51.32) than fillets from birds held at 12 to 18 degrees C (L* = 52.85) or >18 degrees C (L* = 53.11) (P < 0.001). Moreover, the increase in holding temperature (<12 degrees C vs. 12 to 18 degrees C vs. >18 degrees C) also determined a lower breast meat a* (3.77 vs. 3.12 vs. 2.72, respectively; P < 0.001), b* (3.72 vs. 3.41 vs. 3.37, respectively; P < 0.05), C*, and H*. In conclusion, the

  10. Deformation response of paired donor corneas to an air puff: intact whole globe versus mounted corneoscleral rim.

    PubMed

    Metzler, Kimberly M; Mahmoud, Ashraf M; Liu, Jun; Roberts, Cynthia J

    2014-06-01

    To evaluate the influence of ocular shell biomechanical characteristics on corneal deformation response to an air puff. The Ohio State University, Columbus, Ohio, USA. Experimental study. Twenty-four eyes of 12 human donors were obtained in matched pairs. One eye was secured in a purpose-designed whole globe mount (whole-globe group). The cornea from the fellow eye was placed in a Barron artificial anterior chamber (artificial-chamber group). The corneas were mounted sequentially and connected to a pressure-control system. Deformation data were acquired using the Corvis ST, a dynamic Scheimpflug analyzer. Internal pressure was set to 10, 20, 30, 40, and 50 mm Hg; at least 4 examinations were performed at each pressure. Statistically significantly higher maximum deformation amplitude was observed in the whole-globe group than in the artificial-chamber group at all pressures. The mean amplitude differences were 1.006 mm ± 0.238 [SD], 0.614 ± 0.137 mm, 0.384 ± 0.099 mm, 0.229 ± 0.087 mm, and 0.133 ± 0.068 mm at 10, 20, 30, 40, and 50 mm Hg, respectively (P<.0001, P<.0001, P<.0001, P<.0001, and P<.0002, respectively). Nonlinear regression of the deformation amplitude differences between pairs showed a significant decrease with increasing pressure (P<.0001, R(2) = 0.8385). The deformation response to an air puff was affected by the type of mount used, with a stiffer shell producing a stiffer corneal response and decreasing differences at higher internal pressures. In vivo air-puff examinations may be affected by scleral stiffness in addition to the cornea. Dr. Roberts is a consultant to Oculus Optikgeräte GmbH and Ziemer Ophthalmic Systems AG and has received research funding from Carl Zeiss Meditec AG and travel funds from Sooft Italia. No other author has a financial or proprietary interest in any material or method mentioned. Copyright © 2014 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  11. Forecasting database for the tsunami warning regional center for the western Mediterranean Sea

    NASA Astrophysics Data System (ADS)

    Gailler, A.; Hebert, H.; Loevenbruck, A.; Hernandez, B.

    2010-12-01

    pre-computed unit scenarios. The whole notion of a pre-computed forecasting database also requires a historical earthquake and tsunami database, as well as an up-to-date seismotectonic database including faults geometry and a zonation based on seismotectonic synthesis of source zones and tsunamigenic faults. Our forecast strategy is thus based on a unit source function methodology, whereby the model runs are combined and scaled linearly to produce any composite tsunamis propagation solution. Each unit source function is equivalent to a tsunami generated by a Mo 1.75E+19 N.m earthquake (Mw ~6.8) with a rectangular fault 25 km by 20 km in size and 1 m in slip. The faults of the unit functions are placed adjacent to each other, following the discretization of the main seismogenic faults bounding the western Mediterranean basin. The number of unit functions involved varies with the magnitude of the wanted composite solution and the combined waveheights are multiplied by a given scaling factor to produce the new arbitrary scenario. Some test-cases examples are presented (e.g., Boumerdès 2003 [Algeria, Mw 6.8], Djijel 1856 [Algeria, Mw 7.2], Ligure 1887 [Italia, Mw 6.5-6.7]).

  12. Forty years experience in developing and using rainfall simulators under tropical and Mediterranean conditions

    NASA Astrophysics Data System (ADS)

    Pla-Sentís, Ildefonso; Nacci, Silvana

    2010-05-01

    obtained with small size 500-1000 cm2, easily dismantled, drop former simulators, than with larger, nozzle, or more sophisticated equipments. In this contribution there are presented some of the rainfall simulators developed and used by the main author, and some of the results obtained in different studies of practical problems under tropical and Mediterranean conditions. References Pla, I.,G.Campero, y R.Useche.1974.Physical degradación of agricultural soils in the Western Plains of Venezuela. "Trans.10th Int.Cong.Soil.Sci.Soc". 1:231-240. .Moscú Pla, I. 1975.Effects of bitumen emulsion and polyacrilamide on some physical properties of Venezuelan soils. En "Soil Sci. Soc. Am. Special Publication"• 7. 35-46. Madison. Wisconsin . (USA). Pla, I. 1977.Aggregate size and erosion control on sloping land treated with hydrophobic bitumen emulsion."Soil Conservation and Management in the Humid Tropics".109-115. John Wiley & Sons. Pla, I.1981.Simuladores de lluvia para el estudio de relaciones suelo-agua bajo agricultura de secano en los trópicos. Rev. Fac. Agron. XII(1-2):81-93.Maracay (Venezuela) Pla, I. 1986.A routine laboratory index to predict the effects of soil sealing on soil and water conservation. En "Assesment of Soil Surface Sealing and Crusting". 154-162.State Univ. of Ghent.Gante (Bélgica Pla, I., M.C. Ramos, S. Nacci, F. Fonseca y X. Abreu. 2005. Soil moisture regime in dryland vineyards of Catalunya (Spain) as influenced by climate, soil and land management. "Integrated Soil and Water Management for Orchard Development". FAO Land and Water Bulletin 10. 41-49. Roma (Italia).

  13. The Mice Drawer System Tissue Sharing Program (MDS-TSP)

    NASA Astrophysics Data System (ADS)

    Biticchi, Roberta; Cancedda, Ranieri; Cilli, Michele; Cotronei, Vittorio; Costa, Delfina; Liu, Yi; Piccardi, Federica; Pignataro, Salvatore; Ruggiu, Alessandra; Tasso, Roberta; Tavella, Sara

    Several organs and apparatus are affected by weightless conditions and in particular by the weightless experienced during space flights. Therefore space missions are good opportunities to investigate in a whole organism the controlling cellular and molecular mechanisms. For this type of studies mice represent an excellent animal model for several reasons: reduced body size, relatively short time needed to reach adulthood, availability of strains with different genetic background and of different transgenic lines, etc. In line with the International Space Station (ISS) development, the Italian Space Agency (ASI) contracted Thales Alenia Space Italia, the largest Italian aerospace industry, to design and build a spaceflight payload for rodent research on ISS, the Mouse Drawer System (MDS -see abstract P. Cipparelli et al.). This payload meets NIH guideline for several physical parameters to maintain 6 animals in good health conditions in a space environment. Given the interest of our laboratory in the microgravity induced skeleton alterations, we focused our attention on transgenic mice over-expressing pleiotrophin (PTN) under the control of the human bone specific osteocalcin promoter. This protein is a heparin-binding cytokine with different functions. PTN is expressed by the cells in an early differentiation stage and is upregulated in tissue injury and wound repair. PTN is specifically involved in bone formation, neurite outgrowth and angiogenesis. As PTN-transgenic mice show an increased bone mass and mineralization, we decided to use this mouse model in the flight experiment and to study its potential role in counteracting bone loss in microgravity. Not all mouse strains are equally suitable for flight. After preliminary tests in the MDS breadboard at our animal facility on the behavior of different mouse strains, PTN-transgenic mice originally obtained in the BDF strain were backcrossed in the C57Bl/J10 strain before being used in this study. In order to

  14. Utilization of Copper Alloys for Marine Applications

    NASA Astrophysics Data System (ADS)

    Drach, Andrew

    copper alloys is investigated through a series of uniaxial tension tests on virgin and weathered (after one-year deployment in the ocean) specimens. The changes in mechanical properties are quantified in terms of differences in Young's modulus, Poisson's ratio, ultimate strength, and ultimate strain. The obtained stress-strain data is used for numerical modeling of the mechanical behavior of chain-link nets. The simulations are compared with the experimental data on stiffness and strength of the nets. The available information on seawater performance of copper alloys (corrosion, biofouling, mechanics) and copper alloy nets (hydrodynamics) is used to develop engineering procedures for marine aquaculture fish cage systems with copper alloy netting. The design, analysis, and fabrication procedures are illustrated on a commercial size gravity-type offshore fish cage deployed in the Pacific Ocean near Isla Italia (Patagonia, Chile). The funding for this work was provided by the International Copper Association. This work was also supported through two UNH Fellowships: CEPS UNH Graduate Fellowship to Outstanding PhD Program Applicants and Dissertation Year Fellowship.

  15. The role of soil biogeochemistry in wine taste: Soil factors influencing grape elemental composition, photosynthetic biomarkers and Cu/Zn isotopic signature of Vitis vinifera

    NASA Astrophysics Data System (ADS)

    Blotevogel, Simon; Oliva, Priscia; Darrozes, José; Viers, Jérôme; Audry, Stéphane; Courjault-Radé, Pierre; Orgogozo, Laurent; Le Guedard, Marina; Schreck, Eva

    2015-04-01

    Understanding the influence of soil composition in wine taste is of great economic and environmental interest in France and around the world. Nevertheless the impact of soil composition on wine taste is still controversially discussed. Since inorganic soil components do not have a proper taste and do not enter the plant anyway, their influence needs to be induced by nutrient absorption and its impact on plant functioning and grape composition. Indeed recent development of geological tracers of origin proof the existence of soil chemical and isotopic signatures in wine. However, type and scale of the impact of soil composition on wine taste are not well understood yet, and little experimental evidence exists due to the complexity of mechanisms involved. Thus, to provide evidence for the impact of soil composition on grape composition and potentially wine taste, we studied soil and plant material from two relevant vineyards (Soave, Italia). On those two directly adjacent vineyards, two different wines are produced with the same plant material and cultivation techniques. The vineyards only differ by their underlying bedrock - limestone versus basaltic rock - and thus present suitable conditions for investigating the impact of soil composition on grapes and wine. Pedological and mineralogical parameters were analyzed for the two vineyards whereas chemical extractions (citrate, CaCl2) were performed to determine nutrient bioavailability in both soils. Elemental compositions were determined by ICP-MS analyses in different compartments (soils, vine leaves and grapes). Isotopic fractionation of Cu and Zn was investigated in various samples as source tracers and in order to better understand fractionation mechanisms involved. Finally, plant health was studied using the Omega-3 biomarker which determines the fatty acid composition in vine leaves, directly involved in photosynthetic processes. Results show that the vineyards are characterized by two different soil types due

  16. Use of gravity potential field methods for defining a shallow magmatic intrusion: the Mt. Amiata case history (Tuscany, Central Italy)

    NASA Astrophysics Data System (ADS)

    Girolami, Chiara; Rinaldo Barchi, Massimiliano; Pauselli, Cristina; Heyde, Ingo

    2016-04-01

    We analyzed the Bouguer gravity anomaly signal beneath the Mt. Amiata area in order to reconstruct the subsurface setting. The study area is characterized by a pronounced gravity minimum, possibly correlated with the observed anomalous heat flow and hydrothermal activity. Using different approaches, previous authors defined a low density body (generally interpreted as a magmatic intrusion) beneath this area, which could explain the observed gravity anomaly minimum. However the proposed geologic models show different geometries and densities for the batholith. The gravity data used in this study (kindly provided by eni) were acquired from different institutions (eni, OGS, USDMA and Servizio Geologico d'Italia) and collected in a unique dataset, consisting of about 50000 stations, randomly distributed, which cover Central Italy, with a spacing of less than 1 km. For each station the elevation and the Bouguer gravity anomaly data are given. From this dataset, we created two maps of the Bouguer gravity anomaly and the topography, using the Minimum Curvature gridding method considering a grid cell size of 500m x 500m. The Bouguer gravity anomaly has been computed using a density of 2.67 g/cm3. From these maps we extracted a window of about 240 km2 (12x20 km) for the study area, which includes the Mt. Amiata region and the adjacent Radicofani sedimentary basin. The first part of this study was focused on calculating the first order vertical derivative and the power spectra analysis of the Bouguer gravity anomaly to enhance the effect of shallow bodies and estimating the source depth respectively. The second part of this study was focused on constructing a 3D geological density model of the subsurface setting of the studied area, implementing a forward modelling approach. The stratigraphy of the study area's upper crust schematically consists of six litho-mechanical units, whose density was derived from velocity data collected by active seismic surveys. A preliminary

  17. National Workshop on Astrobiology: The Life Science Involvement of AAS I Laben

    NASA Astrophysics Data System (ADS)

    Adami, Giorgio

    2006-12-01

    The search for traces of past and present life is a complex and multidisciplinary research activity involving several scientific heritages and a specific industrial ability for planetary exploration. Laben was established in 1958 to design and manufacture electronic instruments for research in nuclear physics. In the mid 2004 the company was merged with Alenia Spazio. It is now part of Alcatel Alenia Space, a French Italian joint venture. Alcatel Alenia Space Italia SpA is a Finmeccanica Company. Currently the plant of Vimodrone provides a wide heritage in life science oriented to space application. The experience in Space Life Science is consolidated in the following research areas: (1) Physiology: Mouse models related to studies on human physiology Human neuroscience research and dosimetry (2) Animal Adaptation and Behaviour: mice behaviour related to stabling stress (3) Developmental Biology: aquatic microorganisms cultivation (4) Cell culture & Biotechnology: Protein crystal growth General purpose Multiwell Next Biotechnology studies and development: Bio reactor, mainly oriented to tissue engineering Microsensor for tissue control (organ replacement) Multiwell for adherent cell culture or

  18. The Origin of Andesite in the Deep Crust: Evidence from the West-Central Mexican Arc

    NASA Astrophysics Data System (ADS)

    Lange, R. A.; Ownby, S.; Delgado Granados, H.; Hall, C. M.

    2011-12-01

    Although it has long been recognized that andesite is one of the most common magma types erupted at subduction zones and is relatively rare at other tectonic settings, there continues to be a confusing array of different models to explain both its origin and its unique abundance at convergent margins. End-member processes that are most frequently invoked include: (1) crystal fractionation of hydrous basalt (in the upper, middle, and/or lower crust); (2) partial melting of hydrated, mafic lower crust; (3) magma mixing of basalt with rhyolite/dacite; and (4) assimilation of granitoid upper crust by basalt/basaltic andesite. In this study, we test the relative importance of the four end-member differentiation mechanisms to form andesite by examining a segment of the west-central Mexican arc (Michoacán-Guanajuato), which spans ~200 km of arc length and is notable for the scarcity of Quaternary dacite and rhyolite, despite a crustal thickness of ~40-45 km. This arc segment is further remarkable for the relative scarcity of large volcanoes and is instead characterized by >380 small shields (median: <2 km3) and >1000 monogenetic cones and flows. We focused our study on the Tancítaro-Nueva Italia region (~4400 km2), which spans ~80 km of arc length along the volcanic front. On the basis of 65 40Ar/39Ar ages, mapping, and ArcGIS tools, we show that ~326 ± 57 km3 of magma has erupted from > 200 vents since 1.2 Ma. The total proportions of erupted lava types are 6-7% basalt, ~18% basaltic andesite, and ~74-76% andesite. One of the most striking features of this volcanic field is the phenocryst-poor character of lavas erupted from peripheral vents (1-25% crystals) compared to those erupted from the main vent, Volcán Tancítaro (30-45% crystals). Another key observation is that the bulk composition of the crystal-rich andesites are very similar to the most crystal-poor (<5%) andesites, which leads to two conclusions: (1) andesite occurs as a liquid composition, as evidenced

  19. Deep seated gravitational slope deformations and large landslides: implications on landslide hazard of urban areas and coastal erosion phenomena of Mount Poro headland

    NASA Astrophysics Data System (ADS)

    Guerricchio, A.; Simeone, V.

    2012-04-01

    square kilometers. Its movement towards NW produced a typical coastline, with a strong progradation towards NW and W from Punta della Tonnara to Parghelia and up to Fiumara della Ruffa (WSW of Tropea). The DSGSD involves the granitic bedrock as well as the transgressive Tortonian deposits, made by sands with the presence of Clypeasters, which are topped by arenaceous banks, for a total depth of 150 m. DSGSDs involving granitic rocks were probably due to more deformable lithotypes, like biotite schists, which work as substratum of granitic rocks at a not very deep depth, like in other areas of Calabria. Finally, the slow sliding towards N and NW of the landslide shapes the coast like a bow, thus causing strong erosion phenomena of the coastline. Ietto A & Calcaterra D. (1988). Deformazioni gravitative profonde e tettonica presso Tropea (M.te Poro, Calabria)", Memorie della Societa Geologica Italiana, 41, pp. 911-915, Rome, Italy. Guerricchio A. (2000). La fragilità del territorio dell'Italia centro-meridionale desumibile da immagini da satellite. X Congr. Naz. dei Geologi. International Conference: Il Territorio fragile; I, 443-482, Rome, Italy.

  20. National Levee Database: monitoring, vulnerability assessment and management in Italy

    NASA Astrophysics Data System (ADS)

    Barbetta, Silvia; Camici, Stefania; Maccioni, Pamela; Moramarco, Tommaso

    2015-04-01

    A properly designed and constructed levees system can often be an effective device for repelling floodwaters and provide barriers against inundation to protect urbanized and industrial areas. However, the delineation of flooding-prone areas and the related hydraulic hazard mapping taking account of uncertainty (Apel et al., 2008) are usually developed with a scarce consideration of the possible occurrence of levee failures along river channels (Mazzoleni et al., 2014). Indeed, it is well known that flooding is frequently the result of levee failures that can be triggered by several factors, as: (1) overtopping, (2) scouring of the foundation, (3) seepage/piping of levee body/foundation, and (4) sliding of the foundation. Among these failure mechanisms that are influenced by the levee's geometrical configuration, hydraulic conditions (e.g. river level and seepage), and material properties (e.g. permeability, cohesion, porosity, compaction), the piping caused by seepage (ICOLD, http://www.icold-cigb.org) is considered one of the most dominant levee failure mechanisms (Colleselli F., 1994; Wallingford H. R., 2003). The difficulty of estimating the hydraulic parameters to properly describe the seepage line within the body and foundation of the levee implies that the study of the critical flood wave routing is typically carried out by assuming that the levee system is undamaged during the flood event. In this context, implementing and making operational a National Levee Database (NLD), effectively structured and continuously updated, becomes fundamental to have a searchable inventory of information about levees available as a key resource supporting decisions and actions affecting levee safety. The ItaliaN LEvee Database (INLED) has been recently developed by the Research Institute for Geo-Hydrological Protection (IRPI) for the Civil Protection Department of the Presidency of Council of Ministers. INLED has the main focus of collecting comprehensive information about

  1. A new Kinematic Approach to Calculate Seismic Hazard Scenarios (Intensity and Peak Ground Displacement); an Example in SE Sicily

    NASA Astrophysics Data System (ADS)

    Sirovich, L.; Pettenati, F.

    2007-05-01

    The part of the seismic hazard map of Italy (http:zonesismiche.mi.ingv.it/mappa_ps_apr04/italia.html) that regards SE Sicily has recently been modified on the basis also of the new location of the source of one of the strongest earthquakes that ever struck the Mediterranean basin (in 1693 in SE Sicily; 54,000 casualties; see Sirovich and Pettenati, 2001 in BSSA). That source was located inland according to the KF geophysical inversion of the regional damage patterns of the earthquake of Jan. 11, 1693 and of its destructive foreshock of Jan. 9 (see Gentile et al., 2004 in BSSA, and Sirovich and Pettenati, 2004 in JGR, for the genetic KF inversion technique). The damage patterns of Jan. 9 and 11, 1693 had been evaluated by three different groups of historians and seismologists on three different intensity scales. (Detailed information was available from the reports of the Officers of the "Regno delle Due Sicilie" of the time as well as from many other documents). Previously, both earthquakes were traditionally ascribed to the well known Malta Escarpment, the most prominent physiographical and structural feature of the area, which is found offshore, south-east of Sicily. However, given the inland damage of 1693, an offshore epicenter would imply a mean radius of 45 km for the virtual area of degree XI (70 km for degree X) and, thus, a magnitude of 8.3±0.2 with a fault length of approximately 280 km. This fault source would cross the NE part of Sicily from the southern Jonian Sea to the Island of Lipari in the Tyrrhenian Sea; but tectonically this seems unrealistic. All the inversion tests, however, pointed to a complex source inland which could have hosted both earthquakes. Here, we used our kinematic KF model in the direct mode in a parametric, deterministic-Montecarlo way to produce a seismic hazard scenario, in terms of maximum ground displacement. This scenario will be compared with PSHA results for long recurrence times in the frame of a project of the Civil

  2. Internet Use and Access, Behavior, Cyberbullying, and Grooming: Results of an Investigative Whole City Survey of Adolescents

    PubMed Central

    Toaff, Joseph; Pulvirenti, Giuliana; Settanni, Chiara; Colao, Emma; Lavano, Serena Marianna; Cemicetti, Riccardo; Cotugno, David; Perrotti, Giuseppe; Meschesi, Viviana; Montera, Roberto; Zepponi, Barbara

    2017-01-01

    Background According to the Digital Agenda for Europe, the way children use the Internet and mobile technologies has changed dramatically in the past years. Objective The aims of this study were to: (1) breakdown the modalities of access and use of the Internet by teenagers to assess risks and risky behaviors; and (2) provide scientific data to evaluate and counsel safe use of the Internet and new technologies by teenagers. Methods The study was conducted under the program “Strategies for a Better Internet for Children” started in May 2012 by the European Commission. It represents the main result of the project launched by Telecom Italia, “Anche io ho qualcosa da dire” (I too have something to say), thanks to which many contributions were collected and used to develop a survey. The questionnaire was structured in 45 questions, covering three macro areas of interest. It was approved by the Department Board at University of Magna Graecia’s School of Medicine. After authorization from the regional high school authority, it was administered to all 1534 students (aged 13-19 years) in the city of Catanzaro, Italy. Results The data was broken down into three main groups: (1) describing education and access to the Internet; (2) methods of use and social networking; and (3) perception and evaluation of risk and risky behaviors. Among noteworthy results in the first group, we can mention that the average age of first contact with information technologies was around 9 years. Moreover, 78.87% (1210/1534) of the interviewed students reported having access to a smartphone or a tablet. Among the results of the second group, we found that the most used social networks were Facebook (85.78%, 1316/1534), YouTube (61.14%, 938/1534), and Google+ (51.56%, 791/1534). About 71.31% (1094/1534) of the interviewed teenagers use their name and surname on social networks, and 40.09% (615/1534) of them knew all their Facebook contacts personally. Among the results of the third group

  3. Internet Use and Access, Behavior, Cyberbullying, and Grooming: Results of an Investigative Whole City Survey of Adolescents.

    PubMed

    Vismara, Marco Flavio Michele; Toaff, Joseph; Pulvirenti, Giuliana; Settanni, Chiara; Colao, Emma; Lavano, Serena Marianna; Cemicetti, Riccardo; Cotugno, David; Perrotti, Giuseppe; Meschesi, Viviana; Montera, Roberto; Zepponi, Barbara; Rapetto, Umberto; Marotta, Rosa

    2017-08-29

    According to the Digital Agenda for Europe, the way children use the Internet and mobile technologies has changed dramatically in the past years. The aims of this study were to: (1) breakdown the modalities of access and use of the Internet by teenagers to assess risks and risky behaviors; and (2) provide scientific data to evaluate and counsel safe use of the Internet and new technologies by teenagers. The study was conducted under the program "Strategies for a Better Internet for Children" started in May 2012 by the European Commission. It represents the main result of the project launched by Telecom Italia, "Anche io ho qualcosa da dire" (I too have something to say), thanks to which many contributions were collected and used to develop a survey. The questionnaire was structured in 45 questions, covering three macro areas of interest. It was approved by the Department Board at University of Magna Graecia's School of Medicine. After authorization from the regional high school authority, it was administered to all 1534 students (aged 13-19 years) in the city of Catanzaro, Italy. The data was broken down into three main groups: (1) describing education and access to the Internet; (2) methods of use and social networking; and (3) perception and evaluation of risk and risky behaviors. Among noteworthy results in the first group, we can mention that the average age of first contact with information technologies was around 9 years. Moreover, 78.87% (1210/1534) of the interviewed students reported having access to a smartphone or a tablet. Among the results of the second group, we found that the most used social networks were Facebook (85.78%, 1316/1534), YouTube (61.14%, 938/1534), and Google+ (51.56%, 791/1534). About 71.31% (1094/1534) of the interviewed teenagers use their name and surname on social networks, and 40.09% (615/1534) of them knew all their Facebook contacts personally. Among the results of the third group, we found that 7.69% (118/1534) of the

  4. Ocean Literacy from kindergarten to secondary school: a vertically articulated curriculum on marine micro-plastics

    NASA Astrophysics Data System (ADS)

    Realdon, Giulia; Candussio, Giuliana; Manià, Marinella; Palamin, Serenella

    2017-04-01

    dumped plastic, discussing more sustainable management of plastic objects. For older (14-16) students we introduce primary micro-plastics by means of personal care products containing micro-beads: students learn to recognize the presence of micro-beads by reading the product's composition, then measure micro-beads content of one of these products and calculate a possible annual dispersion of micro-beads from their town to the sea. Also this activity is followed by classroom discussion about possible solutions to micro-beads water pollution. Micro-plastics activities have been presented to 39 students' groups since November 2014 and have been evaluated though questionnaires given to class teachers. Lesson plans containing these activities have been published - and are freely accessible - in European and in Italian science teacher's journals (EIROforum Science in School, Pearson Italia Science Magazine).

  5. Innovative SETI by the KLT

    NASA Astrophysics Data System (ADS)

    Maccone, C.

    . Their director, Stelio Montebugnoli, was willing to pay attention to him. Little by little, bright students succeeded in programming the KLT algorithm for the Medicina radio telescopes. Finally, by the year 2000, the advent of programmable cards, mastered by Montebugnoli, made the "miracle" happen. The KLT for SETI is now a reality at the SETI-Italia facilities and for the first time in history. This paper describes the KLT with a final section devoted to the advantages of installing the KLT on LOFAR and the SKA, i.e. to detecting leakage from nearby stars. Bursts, Pulses and Flickering: Wide-field monitoring of the dynamic radio sky Kerastari, Tripolis, Greece 12-15 June, 2007

  6. Timing of porphyry (Cu-Mo) and base metal (Zn-Pb-Ag-Cu) mineralisation in a magmatic-hydrothermal system—Morococha district, Peru

    NASA Astrophysics Data System (ADS)

    Catchpole, Honza; Kouzmanov, Kalin; Bendezú, Aldo; Ovtcharova, Maria; Spikings, Richard; Stein, Holly; Fontboté, Lluís

    2015-12-01

    by more than 0.5 Ma. Polymetallic veins (5.78 ± 0.10 and 5.72 ± 0.18 Ma; 40Ar/39Ar ages) and the Manto Italia polymetallic replacement bodies (6.23 ± 0.12 and 6.0 ± 0.2 Ma; 40Ar/39Ar ages) are interpreted to have been formed by a single hydrothermal pulse. Hydrothermal activity ceased after the formation of the base metal vein and replacement bodies. Overlapping monazite U-Pb (8.26 ± 0.18 Ma) and muscovite 40Ar/39Ar ages (8.1 ± 0.5 Ma) from the early base metal stage of one Cordilleran vein sample in the Sulfurosa area provide evidence that a discrete hydrothermal pulse was responsible for polymetallic vein formation 2.6 Ma prior to the district-wide polymetallic veins. These ages pre-date those of Toromocho porphyry Cu-Mo formation and show that Zn-Pb-Ag-Cu mineralisation formed during several discrete magmatic-hydrothermal pulses in the same district.

  7. Exomars Mission Verification Approach

    NASA Astrophysics Data System (ADS)

    Cassi, Carlo; Gilardi, Franco; Bethge, Boris

    According to the long-term cooperation plan established by ESA and NASA in June 2009, the ExoMars project now consists of two missions: A first mission will be launched in 2016 under ESA lead, with the objectives to demonstrate the European capability to safely land a surface package on Mars, to perform Mars Atmosphere investigation, and to provide communi-cation capability for present and future ESA/NASA missions. For this mission ESA provides a spacecraft-composite, made up of an "Entry Descent & Landing Demonstrator Module (EDM)" and a Mars Orbiter Module (OM), NASA provides the Launch Vehicle and the scientific in-struments located on the Orbiter for Mars atmosphere characterisation. A second mission with it launch foreseen in 2018 is lead by NASA, who provides spacecraft and launcher, the EDL system, and a rover. ESA contributes the ExoMars Rover Module (RM) to provide surface mobility. It includes a drill system allowing drilling down to 2 meter, collecting samples and to investigate them for signs of past and present life with exobiological experiments, and to investigate the Mars water/geochemical environment, In this scenario Thales Alenia Space Italia as ESA Prime industrial contractor is in charge of the design, manufacturing, integration and verification of the ESA ExoMars modules, i.e.: the Spacecraft Composite (OM + EDM) for the 2016 mission, the RM for the 2018 mission and the Rover Operations Control Centre, which will be located at Altec-Turin (Italy). The verification process of the above products is quite complex and will include some pecu-liarities with limited or no heritage in Europe. Furthermore the verification approach has to be optimised to allow full verification despite significant schedule and budget constraints. The paper presents the verification philosophy tailored for the ExoMars mission in line with the above considerations, starting from the model philosophy, showing the verification activities flow and the sharing of tests

  8. Sentinel-1 Mission Overview and Implementation Status

    NASA Astrophysics Data System (ADS)

    Davidson, M.; Attema, E.; Snoeij, P.; Levrini, G.

    2009-04-01

    Sentinel-1 is an imaging radar mission at C-band consisting of a constellation of two satellites aimed at providing continuity of all-weather day-and-night supply of imagery for user services. Special emphasis is placed on services identified in ESA's GMES service elements program and on projects funded by the European Union Framework Programmes. Three priorities (fast-track services) for the mission have been identified by user consultation working groups of the European Union: Marine Core Services, Land Monitoring and Emergency Services. These cover applications such as: - Monitoring sea ice zones and the arctic environment - Surveillance of marine environment - Monitoring land surface motion risks - Mapping of land surfaces: forest, water and soil, agriculture - Mapping in support of humanitarian aid in crisis situations. The Sentinel 1 space segment will be designed and built by an industrial consortium with Thales Alenia Space Italia as prime contractor and EADS Astrium GmbH as C-SAR instrument responsible. Data products from current and previous ESA missions including ERS-1, ERS-2 and Envisat missions form the basis for many of the pilot GMES services. Consequently Sentinel-1 data maintain data quality levels of the Agency‘s previous SAR missions in terms of spatial resolution, sensitivity, accuracy, polarization and wavelength. Nonetheless, the Sentinel-1 synthetic aperture radar (SAR) constellation represents a completely new approach to SAR mission design by ESA in direct response to the operational needs for SAR data expressed under the EU-ESA Global Monitoring for Environment and Security (GMES) programme. The Sentinel-1 constellation is expected to provide near daily coverage over Europe and Canada, global coverage all independent of weather with delivery of radar data within 1 hour of acquisition - all vast improvements with respect to the existing SAR systems. The continuity of C-band SAR data combined with the greatly improved data provision is

  9. Il ruolo svolto dall’attività lavorativa sull’ipertensione arteriosa

    PubMed Central

    Barbini, N.; Gorini, G.; Ferrucci, L.; Biggeri, A.

    2009-01-01

    RIASSUNTO Introduzione I parametri di pressione arteriosa, sistolica (PAS) o diastolica (PAD) hanno costituito I’oggetto di numerosi studi, alcuni dei quali stabiliscono un’associazione tra I’aumnto di tali parametri e la mortalità, in particolare alle età medie. I fattori di rischio di ipertensione più frequentemente studiati sono il consumo di alcol, il fumo e I’origine etnica in riferimento sia alle differenze genetiche che nella condotta alimentare, mentre i fattori di origine professionale sono stati presi in considerazione più raramente e in maniera poco approfondita, inoltre sono state riferite notevoli differenze nelle pressioni arteriose medie di individui che svolgono professioni diverse. Sembra infatti che i “colletti blu” siano più a rischio dei “colletti bianchi”. Obiettivi Il nostro scopo è valutare se determinati rischi o vincoli connessi con l’attività professionale o determinati stili di vita rappresentano un fattore di rischio per l’ipertensione arteriosa in considerazioni dell’aumentare dell’età. Elementi specifici che rendano conto di questa relazione non sono stati ancora completamente chiariti e soprattutto i dati sulla popolazione italiana sono molto limitati. Metodi La metodologia di ricerca utilizzata è stata quella dell’indagine francese ESTEV (Derriennic, Touranchet, Volkoff) - VISAT (Marquie, Janson), studio epidemiologico longitudinale su oltre 23000 lavoratori attivata in Francia nel 1990 al fine di indagare gli effetti a lungo termine delle condizioni di lavoro, riferite all’intera vita professionale, sia sull’invecchiamento sia sulla salute dei lavoratori. Analoga indagine è stata avviata in Italia, nel 2000, in 6 Regioni, prendendo in esame i lavoratori dipendenti di diversi settori produttivi appartenenti a 5 coorti di età: da 32 a 52 anni con intervallo di 5 anni. Le rilevazioni sono state effettuate dai medici del lavoro di azienda attraverso 3 questionari: 1. sulle condizioni

  10. Climate Change Tower Integrated Project (CCT-IP) A scientific platform to investigate processes at the surface and in the low troposphere

    NASA Astrophysics Data System (ADS)

    Vitale, Vito; Udisti, Roberto

    2010-05-01

    V.Vitale, R.Udisti, A.Viola, S.Argentini, M.Nardino, C.Lanconelli, M. Mazzola, T.Georgiadis, R.Salvatori, A.Ianniello, C.Turetta, C.Barbante, F.Spataro, M.Valt, F.Cairo, L.Diliberto, S.Becagli, R.Sparapani, R. Casacchia ************************************************************************ To improve parameterization and reduce uncertainties in climate models, experimental measurements are needed to deep the knowledge on the complex physico-chemical process that characterize the Arctic troposphere and the air-sea-land interaction. Svalbard Islands, located at the northernmost margin of the southern warm current of the Atlantic Ocean, lies in an ideal position to study the combined effects of climate change affecting the atmosphere, as well as the ocean and land. Furthermore, Ny-Ålesund represents a unique site, where international cooperation among countries can allow the monitoring of a greater number of key parameters of the Arctic physical and chemical systems. Based on these remarks, since 2008, CNR Earth and Environment Department sustained and funded the Climate Change Integrate Project ( CCT-IP) in the Kongsfjorden area, aiming to setup a scientific platform at the Italian station "Dirigibile Italia", in Ny Alesund. This platform will be able to complement research activities provided by other national (MIUR-PRIN07) and international research programs. In the framework of this project, it was planned obtaining a comprehensive data set of physical and chemical atmospheric parameters, useful to determine all components of the energy budget at the surface, their temporal variations, and role played by different processes involving air, aerosol, snow, ice and land (permafrost and vegetation). Key element of such platform is the new 32 m high Admundsen-Nobile Climate Change Tower (CCT) that will allow to deeply investigate energy budget and the atmospheric boundary layer dynamics and exchange fluxes (heat, momentum, chemical substances) at the surface. A first

  11. Geochemistry and petrology of the Early Miocene lamproites and related volcanic rocks in the Thrace Basin, NW Anatolia

    NASA Astrophysics Data System (ADS)

    Ersoy, Yalçın E.; Palmer, Martin R.; Uysal, İbrahim; Gündoğan, İbrahim

    2014-08-01

    The extensional Thrace basin (NW Anatolia) contains an association of early Miocene diopside-leucite-phlogopite (Doğanca) and diopside-phlogopite (Korucuköy) lamproites with Oligocene medium-K calc-alkaline andesites (Keşan volcanics), early Miocene shoshonitic rocks (Altınyazı trachyte) and middle Miocene Na-alkaline basalts (Beğendik basalts). The Doğanca lamproite (K2O = 5.1-5.5 wt.%; K/Na = 2.78-2.89; MgO = 11.4-11.8 wt.%) consists of olivine (Fo71-86), diopside (Al2O3 = 1.0-5.0, Na2O = 0.2-0.6), phlogopite (TiO2 = 1.1-9.4, Al2O3 = 11.1-13.9), spinel (Mg# = 22.9-32.6; Cr# = 64-83.4), leucite, apatite, zircon, Fe-Ti-oxides and magnetite in a poikilitic sanidine matrix. The potassic volcanic units (lamproites and trachytes) in the region have similarly high Sr and low Nd isotopic compositions (87Sr/86Sr(i) = 0.70835-0.70873 and 143Nd/144Nd(i) = 0.51227-0.51232). The major and trace element compositions and Sr-Nd-Pb isotopic ratios of the shoshonitic, ultrapotassic and lamproitic units closely resemble those of other Mediterranean ultrapotassic lamproites (i.e., orogenic lamproites) from Italia, Serbia, Macedonia and western Anatolia. The Beğendik basalts show intraplate geochemical signatures with an Na-alkaline composition, an absence of Nb negative anomalies on primitive mantle-normalized multi-element diagrams, as well as low Sr (~ 0.70416) and high Nd (0.51293) isotopic ratios; and include olivine (Fo72-84), diopside, spinel, Fe-Ti-oxides and magnetite. The Oligocene Keşan volcanics were emplaced in the earlier stages of extension in Thrace, and represent the typical volcanic products of post-collisional volcanism. The continental crust-like trace element abundances and isotopic compositions of the most primitive early Miocene ultrapotassic rocks (Mg# up to 74) indicate that their mantle sources were intensely contaminated by the continental material. By considering the geodynamic evolution of the region, including oceanic subduction, crustal

  12. Variability of DTM-derived, morphometric parameters versus cell size. An example of application in Calabria (Southern Italy)

    NASA Astrophysics Data System (ADS)

    Rago, Valeria; Caloiero, Paola; Pellegrino, Annamaria Daniela; Iovine, Giulio G. R.; Terranova, Oreste G.; Pascale, Stefania

    2016-04-01

    , G. Gullà, G. Iovine, O. Petrucci, P. Salvador Sanchis, M. Sorriso-Valvo, O. Terranova, D. Torri, V. Bagarello, C. Di Stefano, V. Ferro, G. Buttafuoco, G. Callegari, P. Porto, B. Betrò, A. Bodini, C. Brambilla (2010) - Relazione Finale Contratto Lotto 2 Pericolosità legata ai fenomeni di intensa erosione idrica areale e lineare- POR Calabria 2000-2006, Azione. 1.4c. Rapporto per Autorità di Bacino Regione Calabria. Iovine G., Greco R., Gariano S.L., Pellegrino A.D., Terranova O.G. (2014) - Shallow-landslide susceptibility in the Costa Viola mountain ridge (southern Calabria, Italy) with considerations on the role of causal factors. Natural Hazards, 73(1), pp.111-136. In: G. Iovine & D. Cohen (Eds.), Advanced methods in landslide modelling. Iovine G., Greco R., Gariano S.L., Iaquinta P., Pellegrino A.D., Terranova O.G. (2013) - Shallow-landslide susceptibility in the Costa Viola mountain ridge (Italia). In: Landslide Science and Practice, Claudio Margottini, Paolo Canuti, Kyoji Sassa (Editors), Volume 3: Spatial Analysis and Modelling, pp.81-87. Proc. Second World Landslide Forum, 3-7 October 2011, Rome.

  13. Social mobility and health in the Turin longitudinal study.

    PubMed

    Cardano, Mario; Costa, Giuseppe; Demaria, Moreno

    2004-04-01

    per l'Italia contemporanea, Il Mulino, Bologna, 1985). Movement out of the labour market was described by a discrete variable with four conditions: employed, unemployed, early retired and women returning from work to the housewife status. The relationship between health status and occupational mobility was analysed via analysis of variance and multinomial logistic regression. Health inequalities were measured by the ratio of standardised mortality rates in the unskilled working class and the upper middle class. The study found a weak relationship between health status and occupational mobility chances. Decidedly stronger was the impact on occupational mobility of gender, education and "ethnicity" (being born in the South of Italy). The relationship between occupational mobility and health takes two different forms. Occupational mobility in the labour market decreases health inequalities; occupational mobility out of the labour market (early retirement, unemployment, housewife return) widens them. The maximum contribution health-related intra-generational social mobility can make towards health inequalities was estimated at about 13% for men.

  14. Relation between "terra rossa" from the Apulia aquifer of Italy and the radon content of groundwater: Experimental results and their applicability to radon occurrence in the aquifer

    NASA Astrophysics Data System (ADS)

    Tadolini, T.; Spizzico, M.

    The radon-222 (222Rn) activity in groundwater of the Apulian karstic aquifer in southern Italy is as great as 500 Becquerel per liter (Bq/L) locally. Normal radium-226 (226Ra) activity in the limestone and calcareous dolomites of the aquifer is not enough to explain such a high level. Laboratory investigations identified high 226Ra activity in the "terra rossa," the residuum occupying fissures and cavities in the bedrock, and also the relation between (1) 226Ra-bearing bedrock and "terra rossa" and (2) 222Rn in water. The "terra rossa" is the primary source of the radon in the groundwater. The experimental results show the need to characterize the "terra rossa" of Apulia on the basis of 226Ra activity and also to study the distribution and variations in 222Rn activity over time in the aquifer. Résumé L'activité du radon-222 (222Rn) dans les eaux souterraines de l'aquifère karstique des Pouilles, dans le sud de l'Italie, atteint localement 500 Becquerel par litre (Bq/L). L'activité normale du radium-226 (226Ra) dans les calcaires et dans les calcaires dolomitiques de l'aquifère n'est pas assez élevée pour expliquer des valeurs aussi élevées. Des analyses de laboratoire ont mis en évidence une forte activité en 226Ra dans la terra rossa, remplissage de fissures et de cavités de la roche, ainsi qu'une relation entre (1) la roche et la terra rossa contenant du 226Ra et (2) le 222Rn dans l'eau. La terra rossa est la source primaire de radon dans l'eau souterraine. Les résultats expérimentaux montrent qu'il est nécessaire de caractériser la terra rossa des Pouilles par son activité en 226Ra et d'étudier la distribution et les variations de l'activité en 222Rn au cours du temps dans l'aquifère. Resumen La actividad del radon-222 (222Rn) en el agua subterránea del acuífero cárstico de Apulia, al sur de Italia, alcanza localmente los 500Bq/L. La actividad normal del radio-226 (226Ra) en las calcitas y dolomitas del acuífero no es suficiente para

  15. Adaptation strategies to water scarcity in the Mediterranean induce a complexification of hydrosystems

    NASA Astrophysics Data System (ADS)

    La Jeunesse, Isabelle; Cirelli, Claudia; Larrue, Corinne; Aubin, David

    2013-04-01

    The Mediterranean and neighboring countries are already experiencing broad range of natural and man-made threats to water security. According to the latest reports of the intergovernmental panel on climate change, the region is at risk due to its pronounced susceptibility to changes in the hydrological budget and extremes. Such changes are expected to have strong impacts on the management of water resources and security from an ecological, economic and social angle. This communication asks the question of the relevance of the comparison of the solutions implemented to face water scarcity in two cases a priori not comparable: (i) the Thau coastal lagoon and its catchment in the South of France, (ii) the Rio Mannu catchment in Sardinia, the second Island in the South of Italia. The Thau coastal lagoon on the French coast is caracterised by intensive shellfish farming production in the lagoon waters and summer tourism with regard to the mediterranean coast. Its territory is also supporting industrial and commercial activities concentrated around Frontignan and Sète ports and the expansion of the small villages of the catchment as the consequence of the connexion with the city of Montpellier. The catchment of the Rio Mannu in South Sardinia is part of the Campidano plain of the Sardinia Island in Italy and is located 30 km close to the city of Cagliari, the capital of the Island. The basin is mainly covered by agricultural fields and grassland, while only a small percentage of its area is occupied by forests in the south-east of the basin. The communication aims, by presenting results of the FP7 EU CLIMB project, to think about the degree of complexity of the dynamic of the stakeholders system for water allocation in the Mediterranean Region in the context of climate change. After the presentation of the case studies and the perception of the water uses by stakeholders, a reflexion on the capacity of stakeholders to represent the new hydrosystems limits is carried out

  16. Geological and geophysical activities at Spallanzani Science Department (Liceo Scientifico Statale "Lazzaro Spallanzani" - Tivoli, Italy)

    NASA Astrophysics Data System (ADS)

    Favale, T.; De Angelis, F.; De Filippis, L.

    2012-04-01

    The high school Liceo Scientifico "Lazzaro Spallanzani" at Tivoli (Rome) has been fully involved in the study of geological and geophysical features of the town of Tivoli and the surrounding area in the last twelve years. Objective of this activity is to promote the knowledge of the local territory from the geological point of view. Main activities: • School year 2001-2002: Setting up inside the school building of a Geological Museum focusing on "Geological Evolution of Latium, Central Italy" (in collaboration with colleagues M. Mancini, and A. Pierangeli). • March, 15, 2001: Conference of Environmental Geology. Lecturer: Prof. Raniero Massoli Novelli, L'Aquila University and Società Italiana di Geologia Ambientale. • School years 2001-2002 and 2002-2003: Earth Sciences course for students "Brittle deformation and tectonic stress in Tivoli area". • November, 2003: Conference of Geology, GIS and Remote Sensing. Lecturers: Prof. Maurizio Parotto and Dr Alessandro Cecili (Roma Tre University, Rome), and Dr Stefano Pignotti (Istituto Nazionale per la Ricerca sulla Montagna, Rome). • November, 2003, 2004 and 2005: GIS DAY, organized in collaboration with ESRI Italia. • School year 2006-2007: Earth Sciences course for students "Acque Albule basin and the Travertine of Tivoli, Latium, Central Italy" (focus on travertine formation). • School year 2010-2011: Earth Sciences course for students "Acque Albule basin and the Travertine of Tivoli. Geology, Hydrogeology and Microbiology of the basin, Latium, Central Italy" (focus on thermal springs and spa). In the period 2009-2010 a seismic station with three channels, currently working, was designed and built in our school by the science teachers Felice De Angelis and Tomaso Favale. Our seismic station (code name LTTV) is part of Italian Experimental Seismic Network (IESN) with identification code IZ (international database IRIS-ISC). The three drums are online in real time on websites http

  17. PREFACE: XIII International Conference on Calorimetry in High Energy Physics (CALOR 2008)

    NASA Astrophysics Data System (ADS)

    Livan, Michele

    2009-07-01

    Advisory Commitee M Danilov, ITEP Moscow M Diemoz, INFN Roma I A Ereditato, Bern F Fabbri, INFN Frascati T Kobayashi, ICEPP Tokyo P Lubrano, INFN Perugia S Magill, ANL Argonne A Maio, LIP Lisbon H Oberlack, MPI Munich A Para, Fermilab K Pretzl, Bern Y Wang, IHEP Beijing R Wigmans, TTU Lubbock R Yoshida, ANL Argonne R Zhu, Caltech Local Organizing Committee R Ferrari, INFN Pavia M Fraternali, Università di Pavia G Gaudio, INFN Pavia M Livan, Università di Pavia (Chair) P Pedroni, INFN Pavia D A Scannicchio, INFN Pavia V Vercesi, INFN Pavia Session Organizers Operating Calorimeters W Sakumoto (University of Rochester) D Schamberger (State University of NY at Stony Brook) Calorimetric Techniques C De La Taille (Université de Paris-Sud) Paul Lecoq (CERN) Frank Maas (GSI-Mainz University) Jan Stark (LPSC Grenoble) Astrophysics and neutrinos I Gil Botella (CIEMAT) A Vacchi (INFN Trieste) LHC P Bloch (CERN) L Serin (Laboratoire de l'Accelerateur Lineaire/IN2P3/CNRS) New Techniques N Akchurin (Texas Tech University) F Salvatore (Royal Holloway University of London) Simulation T Carli (CERN) A Rimoldi (INFN e Università di Pavia) Organization Dipartimento di Fisica Nucleare e Teorica - Università degli Studi di Pavia Istituto Nazionale di Fisica Nucleare - Sezione di Pavia Università degli Studi di Pavia Pragma Congressi, Corso Mazzini, 9 - Pavia Sponsored by CAEN HAMAMATSU Photonis Italia Iseg Spezialelektrinik GmbH Wiener

  18. The Cenomanian-Turonian oceanic anoxic event in Tibet, a real anoxic condition? Clues from Phosphorus, Carbon and Traces Elements accumulations.

    NASA Astrophysics Data System (ADS)

    Bomou, B.; Adatte, T.; Föllmi, K. B.; Caron, M.; Tantawy, A. A.; Fleitmann, D.; Matera, V.; Huang, Y.

    2009-04-01

    a plateau which ends the excursion. A bloom of Heterohelix and Guembelitria, low oxygen tolerant foraminifera, is observed in the upper part of the δ13C shift (W. archaeocretacea zone) indicative of depleted oxygen conditions. Significant peaks in Ptot is observed at the onset of the δ13C shift, followed by a depletion at the end of R. cushmani zone, persisting up to the end of W. archaeocretacea zone. In Tibet, P distribution patterns during OAE2 are quite similar to the ones observed in numerous sections in western Tethys and Central Atlantic (England, Italia, Spain and USA, Mort et al., 2007) and appear therefore to be global, coinciding partly with increased detrital inputs. Trace-metals values are under background level compared with sections characterized by strong anoxic conditions and redox sensitive elements such as Va, Ni, Co, U, generally indicative of anoxic conditions, do not show any increase during the maximum of δ13C excursion and Heterohelix and Guembelitria shifts. This suggests that dysoxic rather than anoxic conditions prevailed in Tibet area during OAE 2. Increased Mg, Na, Ca contents to the detriment of Al suggest a change to more arid climate conditions from the base of archaeocretacea zone upwards. REFERENCES JENKYNS, H.C. (1980). Cretaceous anoxic events: from continents to oceans. Journal of the Geological Society, 137, 171-188. LI, X., JENKYNS, H.C., WANG, C., HU, X., CHEN, X., WEI, Y., HUANG, Y. & CUI, J. (2006). Upper Cretaceous carbon-and oxygen-isotope stratigraphy of hemipelagic carbonate facies from southern Tibet, China. Journal of the Geological Society, 163, 375-382. MORT, H., ADATTE, T., FÖLLMI, K., KELLER, G., STEINMANN, P., MATERA, V., BERNER, Z., & STÜBEN, D. (2007). Phosphorus and the roles of productivity and nutrient recycling during Oceanic Anoxic Event 2. Geology, 35, 6, 483-486. SCHLANGER, S.O. & JENKYNS, H.C. (1976). Cretaceous anoxic events: causes and consequences. Geologie en Mijnbouw, 55, 179-184. SCHOLLE, P

  19. Natalizumab for relapsing remitting multiple sclerosis.

    PubMed

    Pucci, Eugenio; Giuliani, Giorgio; Solari, Alessandra; Simi, Silvana; Minozzi, Silvia; Di Pietrantonj, Carlo; Galea, Ian

    2011-10-05

    Natalizumab (NTZ) (Tysabri(®)) is a monoclonal antibody that inhibits leukocyte migration across the blood-brain barrier, thus reducing inflammation in central nervous system, and has been approved worldwide for the treatment of relapsing-remitting multiple sclerosis (RRMS). To evaluate the efficacy, tolerability and safety of NTZ in the treatment of patients with RRMS. We searched the Cochrane Multiple Sclerosis Group Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, 2010, Issue 1), MEDLINE (PubMed) and EMBASE, all up to 19 February 2010, and bibliographies of papers. Handsearching was carried out. Trialists and pharmaceutical companies were contacted. Furthermore, the websites of US Food and Drug Administration (FDA), the European Medicines Evaluation Agency (EMA) and the National Institute for health and Clinical Excellence (NICE) were also checked. All double-blind, randomised, controlled trials analysing more than a single infusion of NTZ (dosage > 3 mg/kg intravenous infusion every 4 weeks), also including its use as add-on treatment, versus placebo or other drugs in patients with RRMS. No restrictions on the basis of duration of treatment or length of follow up. Three reviewers independently selected articles which met the inclusion criteria. Disagreements were solved by discussion. Two reviewers independently extracted the data and assessed the methodological quality of each trial. Missing data was sought by contacting principal authors and Biogen Idec, through Biogen-Dompé Italia. Three studies met the inclusion criteria. These included one placebo-controlled trial (942 patients) and two add-on placebo-controlled trials, i.e. one plus glatiramer acetate (110 patients) and the second plus interferon beta-1a (1171 patients).This review assessed the efficacy, tolerability and safety of NTZ in patients with RRMS. Data was conclusive with respect to efficacy and tolerability, but not safety. As far as

  20. A dietary supplement improves facial photoaging and skin sebum, hydration and tonicity modulating serum fibronectin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins.

    PubMed

    Di Cerbo, Alessandro; Laurino, Carmen; Palmieri, Beniamino; Iannitti, Tommaso

    2015-03-01

    Excessive exposure to the sun can cause severe photoaging as early as the second decade of life resulting in a loss of physiological elastic fiber functions. We designed a first study to assess differences in facial skin pH, sebum, elasticity, hydration and tonicity and serum levels of fibronectin, elastin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins between patients affected by facial photoaging and healthy controls. In a second study we tested the hypothesis that a dietary supplement would improve facial photoaging, also promoting changes in the above mentioned skin and serum parameters. In the first study we enrolled 30 women [age: 47.5 ± 1.6 years (mean ± standard error of the mean)] affected by moderate facial photoaging (4 cm ≤ Visual Analogue Scale (VAS)<7 cm) and 30 healthy women [age: 45.9 ± 1.6 years (mean ± standard error of the mean)]. In the second study we enrolled a cohort of 30 women [age: 43.6 ± 1.2 years (mean ± standard error of the mean)], affected by moderate (n = 22) and severe (VAS ≥ 7 cm; n = 8) facial photoaging, who were randomized to receive a pharmaceutical formulation (VISCODERM Pearls; IBSA FARMACEUTICI ITALIA Srl, Lodi, Italy) containing Pycnogenol, collagen, coenzyme Q10, low-molecular-weight hyaluronic acid, chondroitin sulfate and glucosamine sulfate (n = 15) or placebo (n = 15). Dietary supplement and placebo were administered 2 times a day for 4 weeks. Facial photoaging was assessed by VAS in the first cohort of patients affected by facial photoaging and healthy controls and, at baseline and 2 weeks after the end of treatment, in the second cohort of patients who underwent treatment with VISCODERM Pearls and placebo. Skin Tester was used to analyze differences in facial skin parameters between patients affected by facial photoaging and healthy controls. Skin Tester was also used to assess the effect of VISCODERM Pearls on facial skin parameters and compared with placebo 2 weeks after the end of

  1. The Project Serapis: High Resolution Seismic Imagingof The Campi Flegrei Caldera Structure

    NASA Astrophysics Data System (ADS)

    Zollo, A.; Virieux, J.; Capuano, P.; Chiarabba, C.; de Franco, R.; Makris, J.; Michelini, A.; Musacchio, G.; Serapis Group

    During September 2001, an extended active seismic survey has been performed in the gulfs of Naples and Pozzuoli in the framework of the so called SERAPIS (SEismic Re- flection Acquisition Project for Imaging Structures). The project SERAPIS is aimed at the acquisition in the bays of Naples and Pozzuoli, on land and at the sea bottom (using sea bottom seismographs), of seismic signals emitted by a very dense network of airgun sources. The energization is performed through the syncronized implosion of bubbles produced by a battery of three to twelve, 16 liters airguns, mounted on the oceanographic vessel NADIR, owned by the french company IFREMER, which supported the project at no cost. The experiment has been designed to have 2D-3D acquisition lay-outs and its objective is the high resolution imaging of the main shal- low crustal discontinuities underneath the major neapolitan volcanic complexes. In particular some desired targets are the location and spatial definition of the magmatic feeding system of Campi Flegrei and the morphologic reconstruction of the interface separating the shallow volcano-alluvium sediments and the Mesozoic carbonates, re- cently detected and accurately imaged underneath Mt.Vesuvius volcano. A secondary but not less important objective is the denser re-sampling of areas in the Bay of Naples prospicient to Mt.Vesuvius, which have been investigated during the last marine sur- vey using the same vessel in 1997 (MareVes 97). Sixty, three-component stations have been installed on-land in the areas of Campi Flegrei, Mt.Vesuvius and on the islands of Ischia and Procida. In particular, the Mt.Vesuvius stations have been deployed along a 40 km long, SE-NW profile crossing the Campanian Plain toward the limestone out- crops. 72 sea bottom seismographs (OBS) have been installed in the gulfs of Naples and Pozzuoli by the University of Hamburg, with the logistic support of Geopro smbh and Geolab Italia. The OBS network geometry follows the main

  2. PREFACE: DICE 2012 : Spacetime Matter Quantum Mechanics - from the Planck scale to emergent phenomena

    NASA Astrophysics Data System (ADS)

    Diósi, Lajos; Elze, Hans-Thomas; Fronzoni, Leone; Halliwell, Jonathan; Prati, Enrico; Vitiello, Giuseppe; Yearsley, James

    2013-06-01

    Milano), F Guerra (Università 'La Sapienza', Roma) and G Vitiello (Università di Salerno), this event traditionally dedicated to the public drew a large audience involved in lively discussions until late. The workshop was organized by L Diósi (Budapest), H-T Elze (Pisa, chair), L Fronzoni (Pisa), J J Halliwell (London), E Prati (Milano) and G Vitiello (Salerno), with most essential help from our conference secretaries L Fratino, N Lampo, I Pozzana, and A Sonnellini, all students from Pisa, and from our former secretaries M Pesce-Rollins and L Baldini. Several institutions and sponsors supported the workshop and their representatives and, in particular, the citizens of Rosignano/Castiglioncello are deeply thanked for the generous help and kind hospitality: Comune di Rosignano - A Franchi (Sindaco di Rosignano), S Scarpellini (Segreteria sindaco), L Benini (Assessore ai lavori pubblici), M Pia (Assessore all' urbanistica) REA Rosignano Energia Ambiente s.p.a. - F Ghelardini (Presidente della REA), E Salvadori and C Peccianti (Segreteria) Associazione Armunia - A Nanni (Direttore), G Mannari (Programmazione), C Perna, F Bellini, M Nannerini, P Bruni and L Meucci (Tecnici). Special thanks go to G Mannari and her collaborators for advice and great help in all the practical matters that had to be dealt with, in order to run the meeting at Castello Pasquini smoothly Funds made available by Università di Pisa, Domus Galilaeana (Pisa), Centro Interdisciplinare per lo Studio dei Sistemi Complessi - CISSC (Pisa), Dipartimento di Ingegneria Industriale (Università di Salerno), Istituto Italiano per gli Studi Filosofici - IISF (Napoli), Solvay Italia SA (Rosignano), Institute of Physics Publishing - IOP (Bristol), Springer Verlag (Heidelberg), and Hungarian Scientific Research Fund OTKA are gratefully acknowledged. Last, but not least, special thanks are due to Laura Pesce (Vitrium Galleria, San Vincenzo) for the exposition of her artwork 'arte e scienza' at Castello Pasquini

  3. Evidence of human-induced morphodynamic changes along the Campania coastal areas (southern Italy) since the 3rd-4th cent. AD

    NASA Astrophysics Data System (ADS)

    Russo Ermolli, Elda; Romano, Paola; Liuzza, Viviana; Amato, Vincenzo; Ruello, Maria Rosaria; Di Donato, Valentino

    2014-05-01

    the first archaic settlement (late 6th cent. BC) was unearthed. The Graeco-Roman town expanded downhill, exploiting the growth of a coastal plain, where occasional phases of flooding coexisted with the life of the citizens [6]. The onset of the 3rd cent. AD was characterized by phases of extreme floods which also occurred during the 4th and 5th cent. AD leading to several meters of ground-level aggradation and the burial of buildings [6, 7]. Although the three investigated sites are located in rather different morphological context, they show the evidence of a disequilibrium in the morphodynamics which started in the 3rd-4th cent. AD. The vast amount of collected data strongly suggest that this disequilibrium is a clear sign of a socio-economic decline which affected the Roman Empire during this period rather than the consequence of a climatic deterioration towards dryer conditions, for which no detailed data are available in the Mediterranean area [8]. The abandonment of the towns and their surroundings triggered increased soil erosion on the slopes suffering deforestation and in the farmlands for reduced maintenance, enhancing accumulation rates at the foothills and along coastal areas. References [1] D'Agostino, B., Giampaola, D., 2005. Osservazioni storiche e archeologiche sulla fondazione di Neapolis, in: Harris, W.V., Lo Cascio, E. (Eds.), Noctes Campanae, studi di storia antica e archeologia dell'Italia pre-romana e romana in memoria di Martin W. Frederiksen, Napoli, 63-72. [2] Giampaola, D., Carsana, V., Boetto, G., Bartolini, M., Capretti, C., Galotta, G., Giachi, G., Macchioni, N., Nugari, M. P., Pizzo, B., 2006. La scoperta del porto di Neapolis: dalla ricostruzione topografica allo scavo e al recupero dei relitti. Arch. Mar. Medit., Int. J. Underwat. Arch. 2, 47-91, Ist. Ed. Poligr.Int. MMVI, Pisa - Roma. [3] Allevato, E., Russo Ermolli, E., Boetto, G., Di Pasquale, G., 2010. Pollen-wood analysis at the Neapolis harbour site (1st-3rd century AD, southern

  4. Calibrazioni a terra e prestazioni in volo di spettrometri ad immagine nel visibile e nel vicino infrarosso per l'esplorazione planetaria

    NASA Astrophysics Data System (ADS)

    Filacchione, Gianrico

    2006-10-01

    -out noise e tilt spettrale); alcuni di questi effetti sono stati caratterizzati e dettagliamente misurati in laboratorio utilizzando il modello spare (flight) di VIMS-V. Parte del capitolo è dedicata alla verifica della procedura di calibrazione su diversi target aventi caratteristiche spettroradiometriche note. Questi algoritmi di processamento sono correntemente utilizzati dal team scientifico di VIMS per calibrare i dati del canale -VIS rilasciati ufficialmente alla comunità scientifica internazionale attraverso il Planetary Data System (PDS) della Nasa. La seconda parte riguarda l’esperimento VIRTIS-M sul satellite Rosetta. Il capitolo 3 contiene la descrizione dello strumento mettendo in risalto l’evoluzione dal precedente progetto VIMS-V ed i problemi tecnologici e costruttivi da questo derivanti. I diversi modi operativi, la sequenza di acquisizione e di processamento dei dati nell’elettronica principale sono ampiament e discussi. Viene inoltre evidenziata la collocazione dello spettrometro sul satellite Rosetta. Nel capitolo 4 viene descritta l’attività di calibrazione effettuata in Galileo Avionica (Campi Bisenzio, FI, Italia) ed allo IAS (Orsay, Francia) subito dopo l’integrazione di VIRTIS ed il conseguente processamento dei dati necessario per ricavare i principali parametri di funzionamento (calibrazioni spettrali e geometriche, flat-field, funzioni di trasferimento, lampade di calibrazione interne). Nel capitolo 5 l’accuratezza di queste grandezze è stata verificata su i primi dati in volo ottenuti da VIRTIS-M durante la fase di commissioning e di cruise del satellite (Terra, Luna e Saturno); queste osservazioni sono inoltre state utilizzate per migliorare e verificare alcuni aspetti della procedura di calibrazione che non erano stati sufficientemente definiti durante i test a terra. L’appendice A riguarda il formato PDS (Planetary Data System) utilizzato per l’archiviazione dei dati e degli housekeepings ingegnerisitici e scientifici delle

  5. ModObs: Atmospheric modelling for wind energy, climate and environment applications : exploring added value from new observation technique

    NASA Astrophysics Data System (ADS)

    Sempreviva, A. M.

    2009-04-01

    ceilometer and radiosoundings during the LASIE (Ligurian Air-Sea Interaction Experiment) campaign sponsored by NATO in the Mediterranean Sea. In-situ and remote-sensing measurements were performed from two measuring platforms, A buoy ODAS, Italia1 and a ship N/O URANIA from the Italian National Council of Research CNR (1), (6) and (7).

  6. ModObs: Atmospheric modelling for wind energy, climate and environment applications: exploring added value from new observation technique. Work in progress within a FP6 Marie Curie Research Training Network

    NASA Astrophysics Data System (ADS)

    Sempreviva, A. M.

    2009-09-01

    both ceilometer and radiosoundings during the LASIE (Ligurian Air-Sea Interaction Experiment) campaign sponsored by NATO in the Mediterranean Sea. In-situ and remote-sensing measurements were performed from two measuring platforms, A buoy ODAS, Italia1 and a ship N/O URANIA from the Italian National Council of Research CNR (1), (6) and (7).

  7. An observatory system for physical and biogeochemical parameters in the northern Adriatic Sea: the "Acqua Alta" oceanographic platform

    NASA Astrophysics Data System (ADS)

    Benetazzo, Alvise; Barbariol, Francesco; Bastianini, Mauro; Bergamasco, Andrea; Bergamasco, Filippo; Bernardi Aubry, Fabrizio; Bertotti, Luciana; Bonaldo, Davide; Cavaleri, Luigi; Carniel, Sandro; Falcieri, Francesco M.; Finotto, Stefania; Lester, Graham; Licer, Matjaz; Malacic, Vlado; Minuzzo, Tiziano; Sclavo, Mauro

    2015-04-01

    during winter 2012. Biological (phyto- and zooplankton) and chemical (dissolved nutrients) measurements are routinely acquired at "Acqua Alta", with periodic sampling on the water column within the Italian Long Term Ecological Research (LTER) network. Two high-resolution webcams have been installed on the submerged structures at -3m and -15m. The main aim is the evaluation of ichthyologic populations of the area for long-term ecological studies, and the real-time images represent a valuable tool as early-warning systems (large mucus aggregates, jellyfish swarms, etc.). A data collection system has been installed in order to test the suitability of OGC Sensor Web Enablement services, exploiting in particular the Sensor Observation Service (SOS) and the associated SensorML and O&M standards (http://geosk.ve.ismar.cnr.it). The toweris also part of the The Aerosol Robotic Network (AERONET), originally developed to evaluate aerosol optical properties and validate satellite retrievals of those properties at various scales with measurements from worldwide distributed autonomous sun photometers Most of the available data are also used to validate operational and research numerical models employed in the area, among which the Italian AdriaROMS 4.0 and NA-COAWST systems, the Slovenian NAPOM and atmosphere-ocean two-way coupled systems, and are related to other existing coastal observatory sites (e.g. the PALOMA buoy in Trieste, http://www.ts.ismar.cnr.it; CNR buoys S1 and E1, http://s1.bo.ismar.cnr.it; the VIDA buoy in Piran, http://buoy.mbss.org). Detailed intercomparisons with the output of meteorological and wave models has allowed a keen correction of the meteorological output, leading to the best wave forecast systems available in the Adriatic and Mediterranean Sea (http://ricerca.ismar.cnr.it/MODELLI/ONDE_MED_ITALIA/page-html/nettuno/NETTUNO2.html). Last but not least, "Acqua Alta" represents a privileged facility for testing "state of the art" ocean technology systems. For

  8. PREFACE: DICE 2008 - From Quantum Mechanics through Complexity to Spacetime: the role of emergent dynamical structures

    NASA Astrophysics Data System (ADS)

    Diósi, Lajos; Elze, Hans-Thomas; Fronzoni, Leone; Halliwell, Jonathan; Vitiello, Giuseppe

    2009-07-01

    Pasquini, which - with its beautiful surroundings, overlooking a piece of Tuscany's coast, and with splendid weather throughout - was conducive to the success of the meeting. The 5-day program was grouped according to the following topics: Quantum Physics and Some Important Questions it Raises Emergent Dynamics, from Quantum to Brain and Beyond Exploring Quantum Mechanics Atomistic Theories of Spacetime Quantum-Entanglement/Gravity/Cosmology A Public Roundtable Discussion formed an integral part of the program under the theme ``Dialoghi sulla complessita' - dall' atomo all' Universo'' and with the participation of physicists and philosophers: F T Arecchi (Firenze), L Fronzoni (Pisa), A M Iacono (Pisa), F Luccio (Pisa) and G Vitiello (Salerno, coordinator). This event drew a large audience, who participated in the lively discussions until late in the evening. The workshop has been organized by L Diósi (Budapest), H-T Elze (Pisa, chair), L Fronzoni (Pisa), J Halliwell (London) and G Vitiello (Salerno), with great help from our conference secretaries M Pesce-Rollins (Siena) and L Baldini (Pisa) and from our students F Caravelli and E Di Nardo, both from Pisa. Several institutions and sponsors generously supported the workshop and their representatives and, in particular, the citizens of Rosignano/Castiglioncello are deeply thanked for the help and kind hospitality: Comune di Rosignano A Nenci (Sindaco di Rosignano), S Scarpellini (Segreteria sindaco), D Del Seppia (Assessore allo Sviluppo Economico del Comune di Rosignano), A Franchi (Assessore al turismo del Comune di Rosignano/Presidente dell' associazione Armunia), A Corsini (Ufficio economato del Comune di Rosignano). REA Rosignano Energia Ambiente s.p.a. F Ghelardini (Presidente della REA), A Cecchini (Ufficio - Responsabile stampa della REA). Solvay Chimica Italia s.a. Dott S Piccoli (Responsabile Relazioni Esterne, Solvay Rosignano), G Becherucci (Comunicazione e Relazioni Esterne). Associazione Armunia M Paganelli

  9. Difficulties in the evaluation and measuring of soil water infiltration

    NASA Astrophysics Data System (ADS)

    Pla-Sentís, Ildefonso

    2013-04-01

    conditions by the land management, but also due to the manipulation of the soil before and during the measurement. Direct "in situ" field evaluations have to be preferred in any case to indirect deductions from other soil characteristics measured under laboratory conditions in the same soils, or in other soils, through the so called "pedo-transfer" functions, or through the use of stochastic models such as the SCS Curve Number Method, or of other models using empirical or physical approaches, which have demonstrated to be of limited value in most of the cases. References Philip, J. R., 1954., An infiltration equation with physical significance: Soil Sci..,v. 77, p. 153-157. Philip, J. R., 1958. The theory of infiltration, pt. 7: Soil Sci., v. 85, no. 6, p. 333-337. Pla, I.1981. Simuladores de lluvia para el estudio de relaciones suelo-agua bajo agricultura de secano en los trópicos. Rev. Fac. Agron. XII(1-2):81-93.Maracay (Venezuela) Pla, I. 1986. A routine laboratory index to predict the effects of soil sealing on soil and water conservation. En "Assesment of Soil Surface Sealing and Crusting". 154-162.State Univ. of Ghent.Gante (Bélgica Pla, I., 1997. A soil water balance model for monitoring soil erosion processes and effects on steep lands in the tropics. Soil Technology. 11(1):17-30. Elsevier Pla, I., M.C. Ramos, S. Nacci, F. Fonseca y X. Abreu. 2005. Soil moisture regime in dryland vineyards of Catalunya (Spain) as influenced by climate, soil and land management. "Integrated Soil and Water Management for Orchard Development". FAO Land and Water Bulletin 10. 41-49. Roma (Italia). Pla, I., 2006. Hydrological approach for assessing desertification processes in the Mediterranean region. In W.G. Kepner et al. (Editors), Desertification in the Mediterranean Region. A Security Issue. 579-600 Springer. Heidelberg (Germany) Pla, I. 2011. Evaluación y Modelización Hidrológica para el Diagnóstico y Prevención de "Desastres Naturales". Gestión y Ambiente 14 (3): 17-22. UN

  10. Water-gas dynamics and coastal land subsidence over Chioggia Mare field, northern Adriatic Sea

    NASA Astrophysics Data System (ADS)

    Teatini, Pietro; Baú, Domenico; Gambolati, Giuseppe

    2000-09-01

    menace potentielle pour la ville de Venise, à 25 km au nord-ouest du centre de Chioggia Mare. Afin d'évaluer le risque de subsidence du sol provoquée par les prélèvements de gaz, un modèle numérique a été développé pour prévoir la compaction des formations réservoirs de gaz en même temps que celle de l'aquifère latéral et sous-jacent, par effet de drainance, sur une période de 13 ans de production, suivie de 12 ans, et pour prévoir le transfert de la compaction profonde jusqu'à la surface du sol. Afin de prendre en compte l'incertitude sur un petit nombre de paramètres hydromécaniques importants, plusieurs scénarios ont été simulés et les prévisions les plus pessimistes ont été obtenues. Les résultats de la modélisation montrent qu'on doit s'attendre, au cours des 25 ans, au plus à une subsidence du sol de 1 cm à Chioggia, tandis que Venise ne subira aucun effet. Si la baisse de l'aquifère est compensée par une injection d'eau, la subsidence du sol s'arrêtera à 5 km au large et la zone côtière de Chioggia subira un effet de 0,6 à 0,7 cm. Resumen. Recientemente, la compañía nacional italiana del petróleo, ENI-Agip, ha enviado al Ministerio de Medio Ambiente de Italia (Comité VIA) un gran programa de desarrollo de 15 campos de gas en el norte del Mar Adriático para la evaluación de su impacto medioambiental. Una de las reservas principales de gas se halla en el mar de Chioggia, a unos 10 km mar adentro de la costa veneciana, a una profundidad de entre 1.000 y 1.400 m. Se espera que la producción en este campo produzca un impacto en la estabilidad de la línea de costa, y que suponga una amenaza potencial para la ciudad de Venecia, situada a 25 km al noroeste de la explotación. Se desarrolló un modelo numérico para evaluar el riesgo de subsidencia debido a la extracción de gas a lo largo de los 13 años de producción y del período post-productivo de 12 años. Sus predicciones indican que se causará la compactación tanto

  11. First Temperate Exoplanet Sized Up

    NASA Astrophysics Data System (ADS)

    2010-03-01

    (Hawaii), the Isaac Newton Telescope (Roque de los Muchachos Observatory), Wise Observatory (Israel), the Faulkes North Telescope of the Las Cumbres Observatory Global Telescope Network (Hawaii) and the ESO 3.6-metre telescope (Chile). More information This research was presented in a paper published this week in Nature ("A transiting giant planet with a temperature between 250 K and 430 K"), by H. J. Deeg et al. The team is composed of H.J. Deeg, B. Tingley, J.M. Almenara, and M. Rabus (Instituto de Astrofısica de Canarias, Tenerife, Spain), C. Moutou, P. Barge, A. S. Bonomo, M. Deleuil, J.-C. Gazzano, L. Jorda, and A. Llebaria (Laboratoire d'Astrophysique de Marseille, Université de Provence, CNRS, OAMP, France), A. Erikson, Sz. Csizmadia, J. Cabrera, P. Kabath, H. Rauer (Institute of Planetary Research, German Aerospace Center, Berlin, Germany), H. Bruntt, M. Auvergne, A. Baglin, D. Rouan, and J. Schneider (Observatoire de Paris-Meudon, France), S. Aigrain and F. Pont (University of Exeter, UK), R. Alonso, C. Lovis, M. Mayor, F. Pepe, D. Queloz, and S. Udry (Observatoire de l'Université de Genève, Switzerland), M. Barbieri (Università di Padova, Italia), W. Benz (Universität Bern, Switzerland), P. Bordé, A. Léger, M. Ollivier, and B. Samuel (Institut d'Astrophysique Spatiale, Université Paris XI, Orsay, France), F. Bouchy and G. Hébrard (IAP, Paris, France), L. Carone and M. Pätzold (Rheinisches Institut für Umweltforschung an der Universität zu Köln, Germany), S. Carpano, M. Fridlund, P. Gondoin, and R. den Hartog (ESTEC/ESA, Noordwijk, The Netherlands), D. Ciardi (NASA Exoplanet Science Institute/Caltech, USA), R. Dvorak (University of Vienna, Austria), S. Ferraz-Mello (Universidade de São Paulo, Brasil), D. Gandolfi, E. Guenther, A. Hatzes, G. Wuchterl, B. Stecklum (Thüringer Landessternwarte, Tautenburg, Germany), M. Gillon (University of Liège, Belgium), T. Guillot and M. Havel (Observatoire de la Côte d' Azur, Nice, France), M. Hidas, T. Lister

  12. The joint in vitro action of polymyxin B and miconazole against pathogens associated with canine otitis externa from three European countries

    PubMed Central

    Pietschmann, Silvia; Meyer, Michael; Voget, Michael; Cieslicki, Michael

    2013-01-01

    . aeruginosa (FICI = 0.25 et 0.50, respectivement), alors qu'aucune interaction n'a été mise en évidence contre les souches de S. pseudintermedius (FICI = 1.25). Les souches de Proteus mirabilis n'ont été inhibées par aucune des molécules, individuellement ou en association. Conclusions et importance clinique La synergie in vitro de la polymyxine B et du miconazole contre les souches d'E. coli et de P. aeruginosa justifie l'application de la combinaison des deux agents dans le traitement de l'otite externe lors d'infection par ces bactéries. Resumen Introducción la otitis externa canina, inflamación del canal auditivo externo, puede perpetuarse y empeorar debido a la presencia de infecciones bacterianas o fúngicas. Para el tratamiento tópico se utilizan fundamentalmente combinaciones de ingredientes antiinflamatorios y antimicrobianos. Hipótesis/objetivos este estudio se condujo para elucidar la actividad in vitro de polimixina B y miconazol frente a aislados clínicos bacterianos de tres países europeos, investigar posibles diferencias en sensibilidad y analizar interacciones de fármacos. Animales diecisiete cepas de Escherichia coli, 24 cepas de Pseudomonas aeruginosa, 24 cepas de Proteus mirabilis y 25 cepas de Staphylococcus pseudintermedius de perros diagnosticados con otitis externa asilados de Alemania, Francia e Italia. Métodos se evaluó la actividad de los fármacos mediante la concentración inhibitoria minima (MIC) y la concentración bactericida minima. La potenciación de polimixina B y miconazol se calculó usando el índice de concentración fraccional inhibitoria (FICI). Un FICI≤ 0,5 definía sinergismo. Además se analizaron estadísticamente las variaciones en la FICI y MIC dependiendo de la región de origen. Resultados la susceptibilidad bacteriana fue comparable en los diferentes países europeos ya que no hubo diferencias significativas en MIC y FICI (P > 0,05). Como agente único la polimixina B tuvo actividad antimicrobiana frente a la