Sample records for biointeractive physical size

  1. Framing the nano-biointeractions by proteomics

    NASA Astrophysics Data System (ADS)

    Sabella, S.; Maiorano, G.; Rizzello, L.; Kote, S.; Cingolani, R.; Pompa, P. P.

    2012-03-01

    Knowledge of the molecular mechanisms underlying the interactions between nanomaterials and living systems is fundamental for providing more effective products for nanomedicine and drug delivery. Controlling the response of cells/bacteria (such as activation of inflammatory processes or apoptosis/necrosis in tumor cells or pathogenic bacteria) by tuning specific properties of the nanomaterials is ultimately the challenging goal. Notably, this may also provide crucial information in the assessment of any toxic risks induced by nanoparticles on humans. However, in studying the nano-biointeractions, it is imperative to take into account the dynamic evolutions of nanoparticles in the biological environments (in terms of protein corona formation, size and charge changes) in synergy with the dynamic events occurring in cells, including signal transduction, metabolic processes, homeostasis and membrane trafficking. In this context, we discuss the impact of analytical technologies, especially in the field of proteomics, which can provide major insights into the processes affecting the NPs surface as well as the cells and bacteria functionalities. In particular, we show that a precise control of the chemical-physical characteristics of the interacting nanoparticles or nanostructures may impact the cells by inducing changes in the proteomic profiles with direct consequences on their viability.

  2. Material nanosizing effect on living organisms: non-specific, biointeractive, physical size effects

    PubMed Central

    Watari, Fumio; Takashi, Noriyuki; Yokoyama, Atsuro; Uo, Motohiro; Akasaka, Tsukasa; Sato, Yoshinori; Abe, Shigeaki; Totsuka, Yasunori; Tohji, Kazuyuki

    2009-01-01

    Nanosizing effects of materials on biological organisms was investigated by biochemical cell functional tests, cell proliferation and animal implantation testing. The increase in specific surface area causes the enhancement of ionic dissolution and serious toxicity for soluble, stimulative materials. This effect originates solely from materials and enhances the same functions as those in a macroscopic size as a catalyst. There are other effects that become prominent, especially for non-soluble, biocompatible materials such as Ti. Particle size dependence showed the critical size for the transition of behaviour is at approximately 100 μm, 10 μm and 200 nm. This effect has its origin in the biological interaction process between both particles and cells/tissue. Expression of superoxide anions, cytokines tumour necrosis factor-α and interleukin-1β from neutrophils was increased with the decrease in particle size and especially pronounced below 10 μm, inducing phagocytosis to cells and inflammation of tissue, although inductively coupled plasma chemical analysis showed no dissolution from Ti particles. Below 200 nm, stimulus decreases, then particles invade into the internal body through the respiratory or digestive systems and diffuse inside the body. Although macroscopic hydroxyapatite, which exhibits excellent osteoconductivity, is not replaced with natural bone, nanoapatite composites induce both phagocytosis of composites by osteoclasts and new bone formation by osteoblasts when implanted in bone defects. The progress of this bioreaction results in the conversion of functions to bone substitution. Although macroscopic graphite is non-cell adhesive, carbon nanotubes (CNTs) are cell adhesive. The adsorption of proteins and nano-meshwork structure contribute to the excellent cell adhesion and growth on CNTs. Non-actuation of the immune system except for a few innate immunity processes gives the non-specific nature to the particle bioreaction and restricts reaction to the size-sensitive phagocytosis. Materials larger than cell size, approximately 10 μm, behave inertly, but those smaller become biointeractive and induce the intrinsic functions of living organisms. This bioreaction process causes the conversion of functions such as from biocompatibility to stimulus in Ti-abraded particles, from non-bone substitutional to bone substitutional in nanoapatite and from non-cell adhesive to cell adhesive CNTs. The insensitive nature permits nanoparticles that are less than 200 nm to slip through body defence systems and invade directly into the internal body. PMID:19364724

  3. Electrochemical monitoring of biointeraction by graphene-based material modified pencil graphite electrode.

    PubMed

    Eksin, Ece; Zor, Erhan; Erdem, Arzum; Bingol, Haluk

    2017-06-15

    Recently, the low-cost effective biosensing systems based on advanced nanomaterials have received a key attention for development of novel assays for rapid and sequence-specific nucleic acid detection. The electrochemical biosensor based on reduced graphene oxide (rGO) modified disposable pencil graphite electrodes (PGEs) were developed herein for electrochemical monitoring of DNA, and also for monitoring of biointeraction occurred between anticancer drug, Daunorubicin (DNR), and DNA. First, rGO was synthesized chemically and characterized by using UV-Vis, TGA, FT-IR, Raman Spectroscopy and SEM techniques. Then, the quantity of rGO assembling onto the surface of PGE by passive adsorption was optimized. The electrochemical behavior of rGO-PGEs was examined by cyclic voltammetry (CV). rGO-PGEs were then utilized for electrochemical monitoring of surface-confined interaction between DNR and DNA using differential pulse voltammetry (DPV) technique. Additionally, voltammetric results were complemented with electrochemical impedance spectroscopy (EIS) technique. Electrochemical monitoring of DNR and DNA was resulted with satisfying detection limits 0.55µM and 2.71µg/mL, respectively. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. A guide for building biological pathways along with two case studies: hair and breast development.

    PubMed

    Trindade, Daniel; Orsine, Lissur A; Barbosa-Silva, Adriano; Donnard, Elisa R; Ortega, J Miguel

    2015-03-01

    Genomic information is being underlined in the format of biological pathways. Building these biological pathways is an ongoing demand and benefits from methods for extracting information from biomedical literature with the aid of text-mining tools. Here we hopefully guide you in the attempt of building a customized pathway or chart representation of a system. Our manual is based on a group of software designed to look at biointeractions in a set of abstracts retrieved from PubMed. However, they aim to support the work of someone with biological background, who does not need to be an expert on the subject and will play the role of manual curator while designing the representation of the system, the pathway. We therefore illustrate with two challenging case studies: hair and breast development. They were chosen for focusing on recent acquisitions of human evolution. We produced sub-pathways for each study, representing different phases of development. Differently from most charts present in current databases, we present detailed descriptions, which will additionally guide PESCADOR users along the process. The implementation as a web interface makes PESCADOR a unique tool for guiding the user along the biointeractions, which will constitute a novel pathway. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Surface Plasmon Resonance of Counterions coated Charged Silver Nanoparticles and Application in Bio-interaction

    NASA Astrophysics Data System (ADS)

    Ghosh, Goutam; Panicker, Lata; Naveen Kumar, N.; Mallick, Vivek

    2018-05-01

    Silver nanoparticles (SNPs) play very significant roles in biomedical applications, e.g., biosensors in numerous assays for quantitative detection, and the surface chemistry adds an important factor in that. In this investigation, we coated SNPs either by anionic citrates, like tri-lithium citrate (TLC) or tri-potassium citrate (TKC) which are associated with Li+ or K+ counterions, respectively; or by cationic surfactants, like cetylpyridinium chloride (CPC) or cetylpyridinium iodide (CPI) which are associated with Cl‑ or I‑ counterions, respectively, at the surface of nanoparticles. Our aim was to study (i) how the counterions affect the optical property of SNPs and (ii) the interaction of coated SNPs with a protein, hen egg white lysozyme (HEWL). Transmission electron microscopy (TEM) and dynamic light scattering (DLS) techniques were used to measure the size, and UV absorption spectroscopy was used to characterize the surface plasmon resonance (SPR) band of SNPs. ζ-potential, fluorescence quenching and circular dichroism (CD) spectroscopy techniques were used for characterizing the protein-nanoparticles interaction.

  6. Conference on Surfaces of Biomaterials Biotechnology - Biointeractions 󈨛 Held in Cambridge, United Kingdom on 6-8 July 1987

    DTIC Science & Technology

    1987-12-15

    interactions (ac- either positive or negative surface cording to Bakker), occurred for all charge and ]inked this to OB bchavior. tested btomaterinls, but were...an~d 10 weeks. treated for edentulousuesa an excellent At t*e end of the test period, the imp- function can be a-intained for decades. plants vers...covotiers and tested in tjtmro as probably collagen) rather than synovium potential intestinal bloadhesives. The is the sperific target for microbial ad

  7. Biophysical evaluation of radiofrequency electromagnetic field effects on male reproductive pattern.

    PubMed

    Kesari, Kavindra Kumar; Kumar, Sanjay; Nirala, Jayprakash; Siddiqui, Mohd Haris; Behari, Jitendra

    2013-03-01

    There are possible hazardous health effects of exposure to radiofrequency electromagnetic radiations emitted from mobile phone on the human reproductive pattern. It is more effective while keeping mobile phones in pocket or near testicular organs. Present review examines the possible concern on radio frequency radiation interaction and biological effects such as enzyme induction, and toxicological effects, including genotoxicity and carcinogenicity, testicular cancer, and reproductive outcomes. Testicular infertility or testicular cancer due to mobile phone or microwave radiations suggests an increased level of reactive oxygen species (ROS). Though generation of ROS in testis has been responsible for possible toxic effects on physiology of reproduction, the reviews of last few decades have well established that these radiations are very harmful and cause mutagenic changes in reproductive pattern and leads to infertility. The debate will be focused on bio-interaction mechanism between mobile phone and testicular cancer due to ROS formation. This causes the biological damage and leads to several changes like decreased sperm count, enzymatic and hormonal changes, DNA damage, and apoptosis formation. In the present review, physics of mobile phone including future research on various aspects has been discussed.

  8. Isolation and purification assay of ex vivo photosystem II D1 protein toward integrated biointeraction analysis.

    PubMed

    Muktiono, B; Schulten, C; Heemken, O; Gandrass, J; Prange, A; Schnabl, H; Cerboncini, C

    2008-02-01

    Protein extracts of photosystem II were prepared from leaf chloroplasts of different plant species by fast and nondenaturing methods. Sodium dodecyl sulfate polyacrylamide gel electrophoresis and western blot analysis of the proteins obtained showed that the extracts were enriched by D1 proteins, which appeared putatively in association with the 33-kDa oxygen-evolving-complex subunits. In further isolation steps D1 proteins were purified using salt-gradient chromatography (fast protein liquid chromatography) and characterized by western blot and mass spectrometry.

  9. Atomic Force Microscopy: A Powerful Tool to Address Scaffold Design in Tissue Engineering.

    PubMed

    Marrese, Marica; Guarino, Vincenzo; Ambrosio, Luigi

    2017-02-13

    Functional polymers currently represent a basic component of a large range of biological and biomedical applications including molecular release, tissue engineering, bio-sensing and medical imaging. Advancements in these fields are driven by the use of a wide set of biodegradable polymers with controlled physical and bio-interactive properties. In this context, microscopy techniques such as Atomic Force Microscopy (AFM) are emerging as fundamental tools to deeply investigate morphology and structural properties at micro and sub-micrometric scale, in order to evaluate the in time relationship between physicochemical properties of biomaterials and biological response. In particular, AFM is not only a mere tool for screening surface topography, but may offer a significant contribution to understand surface and interface properties, thus concurring to the optimization of biomaterials performance, processes, physical and chemical properties at the micro and nanoscale. This is possible by capitalizing the recent discoveries in nanotechnologies applied to soft matter such as atomic force spectroscopy to measure surface forces through force curves. By tip-sample local interactions, several information can be collected such as elasticity, viscoelasticity, surface charge densities and wettability. This paper overviews recent developments in AFM technology and imaging techniques by remarking differences in operational modes, the implementation of advanced tools and their current application in biomaterials science, in terms of characterization of polymeric devices in different forms (i.e., fibres, films or particles).

  10. The New Toxicology of Sophisticated Materials: Nanotoxicology and Beyond

    PubMed Central

    Maynard, Andrew D.; Warheit, David B.; Philbert, Martin A.

    2011-01-01

    It has long been recognized that the physical form of materials can mediate their toxicity—the health impacts of asbestiform materials, industrial aerosols, and ambient particulate matter are prime examples. Yet over the past 20 years, toxicology research has suggested complex and previously unrecognized associations between material physicochemistry at the nanoscale and biological interactions. With the rapid rise of the field of nanotechnology and the design and production of increasingly complex nanoscale materials, it has become ever more important to understand how the physical form and chemical composition of these materials interact synergistically to determine toxicity. As a result, a new field of research has emerged—nanotoxicology. Research within this field is highlighting the importance of material physicochemical properties in how dose is understood, how materials are characterized in a manner that enables quantitative data interpretation and comparison, and how materials move within, interact with, and are transformed by biological systems. Yet many of the substances that are the focus of current nanotoxicology studies are relatively simple materials that are at the vanguard of a new era of complex materials. Over the next 50 years, there will be a need to understand the toxicology of increasingly sophisticated materials that exhibit novel, dynamic and multifaceted functionality. If the toxicology community is to meet the challenge of ensuring the safe use of this new generation of substances, it will need to move beyond “nano” toxicology and toward a new toxicology of sophisticated materials. Here, we present a brief overview of the current state of the science on the toxicology of nanoscale materials and focus on three emerging toxicology-based challenges presented by sophisticated materials that will become increasingly important over the next 50 years: identifying relevant materials for study, physicochemical characterization, and biointeractions. PMID:21177774

  11. Novel dimer based descriptors with solvational computation for QSAR study of oxadiazoylbenzoyl-ureas as novel insect-growth regulators.

    PubMed

    Fan, Feng; Cheng, Jiagao; Li, Zhong; Xu, Xiaoyong; Qian, Xuhong

    2010-02-01

    Molecular aggregation state of bioactive compounds plays a key role in its bio-interactive procedure. In this article, based on the structure information of dimers, the simplest model of molecular aggregation state, and combined with solvational computation, total four descriptors (DeltaV, MR2, DeltaE(1), and DeltaE(2)) were calculated for QSAR study of a novel insect-growth regulator, N-(5-phenyl-1,3,4-oxadiazol-2-yl)-N'-benzoyl urea. Two QSAR models were constructed with r(2) = 0.671, q(2) = 0.516 and r(2) = 0.816, q(2) = 0.695, respectively. It implicates that the bioactivity may strongly depend on the characters of molecular aggregation state, especially on the dimeric transport ability from oil phase to water phase. Copyright 2009 Wiley Periodicals, Inc.

  12. Optofluidic lasers and their applications in bioanalysis (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Fan, Xudong

    2016-03-01

    The optofluidic laser is an emerging technology that integrates microfluidics, miniaturized laser cavity, and laser gain medium in liquid. It is unique due to its biocompatibility, thus can be used for unconventional bioanalysis, in which biointeraction or process takes place within the optical cavity mode volume. Rather than using fluorescence, the optofluidic laser based detection employs laser emission, i.e., stimulated emission, as the sensing signal, which takes advantage of optical amplification provided by the laser cavity to achieve much higher sensitivity. In this presentation, I will first introduce the concept of optofluidic laser based bioanalysis. Then I will discuss each of the three components (cavity, gain medium, and fluidics) of the optofluidic laser and describe how to use the optofluidic laser in bioanalysis at the molecular, cellular, and tissue level. Finally, I will discuss future research and application directions.

  13. Properties of a novel polysiloxane-guttapercha calcium silicate-bioglass-containing root canal sealer.

    PubMed

    Gandolfi, M G; Siboni, F; Prati, C

    2016-05-01

    Root canal filling sealers based on polymethyl hydrogensiloxane or polymethyl hydrogensiloxane-guttapercha--introduced to improve the quality of conventional guttapercha-based and resin-based systems--showed advantages in handiness and clinical application. The aim of the study was to evaluate the chemical-physical properties of a novel polysiloxane-guttapercha calcium silicate-containing root canal sealer (GuttaFlow bioseal). GuttaFlow bioseal was examined and compared with GuttaFlow2, RoekoSeal and MTA Fillapex sealers. Setting times, open and impervious porosity and apparent porosity, water sorption, weight loss, calcium release, and alkalinizing activity were evaluated. ESEM-EDX-Raman analyses of fresh materials and after soaking in simulated body fluid were also performed. Marked differences were obtained among the materials. GuttaFlow bioseal showed low solubility and porosity, high water sorption, moderate calcium release and good alkalinizing activity. MTA Fillapex showed the highest calcium release, alkalinizing activity and solubility, RoekoSeal the lowest calcium release, no alkalinizing activity, very low solubility and water sorption. Only GuttaFlow bioseal showed apatite forming ability. GuttaFlow bioseal showed alkalinizing activity together with negligible solubility and slight calcium release. Therefore, the notable nucleation of apatite and apatite precursors can be related to the co-operation of CaSi particles (SiOH groups) with polysiloxane (SiOSi groups). The incorporation of a calcium silicate component into polydimethyl polymethylhydrogensiloxane guttapercha sealers may represent an attractive strategy to obtain a bioactive biointeractive flowable guttapercha sealer for moist/bleeding apices with bone defects in endodontic therapy. Copyright © 2016 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  14. Three-body system metaphor for the two-slit experiment and Escherichia coli lactose-glucose metabolism.

    PubMed

    Asano, Masanari; Khrennikov, Andrei; Ohya, Masanori; Tanaka, Yoshiharu; Yamato, Ichiro

    2016-05-28

    We compare the contextual probabilistic structures of the seminal two-slit experiment (quantum interference experiment), the system of three interacting bodies andEscherichia colilactose-glucose metabolism. We show that they have the same non-Kolmogorov probabilistic structure resulting from multi-contextuality. There are plenty of statistical data with non-Kolmogorov features; in particular, the probabilistic behaviour of neither quantum nor biological systems can be described classically. Biological systems (even cells and proteins) are macroscopic systems and one may try to present a more detailed model of interactions in such systems that lead to quantum-like probabilistic behaviour. The system of interactions between three bodies is one of the simplest metaphoric examples for such interactions. By proceeding further in this way (by playing withn-body systems) we shall be able to find metaphoric mechanical models for complex bio-interactions, e.g. signalling between cells, leading to non-Kolmogorov probabilistic data. © 2016 The Author(s).

  15. Dual-Mode Electro-Optical Techniques for Biosensing Applications: A Review

    PubMed Central

    Johnson, Steven

    2017-01-01

    The monitoring of biomolecular interactions is a key requirement for the study of complex biological processes and the diagnosis of disease. Technologies that are capable of providing label-free, real-time insight into these interactions are of great value for the scientific and clinical communities. Greater understanding of biomolecular interactions alongside increased detection accuracy can be achieved using technology that can provide parallel information about multiple parameters of a single biomolecular process. For example, electro-optical techniques combine optical and electrochemical information to provide more accurate and detailed measurements that provide unique insights into molecular structure and function. Here, we present a comparison of the main methods for electro-optical biosensing, namely, electrochemical surface plasmon resonance (EC-SPR), electrochemical optical waveguide lightmode spectroscopy (EC-OWLS), and the recently reported silicon-based electrophotonic approach. The comparison considers different application spaces, such as the detection of low concentrations of biomolecules, integration, the tailoring of light-matter interaction for the understanding of biomolecular processes, and 2D imaging of biointeractions on a surface. PMID:28880211

  16. Three-body system metaphor for the two-slit experiment and Escherichia coli lactose–glucose metabolism

    PubMed Central

    Asano, Masanari; Ohya, Masanori; Yamato, Ichiro

    2016-01-01

    We compare the contextual probabilistic structures of the seminal two-slit experiment (quantum interference experiment), the system of three interacting bodies and Escherichia coli lactose–glucose metabolism. We show that they have the same non-Kolmogorov probabilistic structure resulting from multi-contextuality. There are plenty of statistical data with non-Kolmogorov features; in particular, the probabilistic behaviour of neither quantum nor biological systems can be described classically. Biological systems (even cells and proteins) are macroscopic systems and one may try to present a more detailed model of interactions in such systems that lead to quantum-like probabilistic behaviour. The system of interactions between three bodies is one of the simplest metaphoric examples for such interactions. By proceeding further in this way (by playing with n-body systems) we shall be able to find metaphoric mechanical models for complex bio-interactions, e.g. signalling between cells, leading to non-Kolmogorov probabilistic data. PMID:27091163

  17. Biosensors based on cantilevers.

    PubMed

    Alvarez, Mar; Carrascosa, Laura G; Zinoviev, Kiril; Plaza, Jose A; Lechuga, Laura M

    2009-01-01

    Microcantilevers based-biosensors are a new label-free technique that allows the direct detection of biomolecular interactions in a label-less way and with great accuracy by translating the biointeraction into a nanomechanical motion. Low cost and reliable standard silicon technologies are widely used for the fabrication of cantilevers with well-controlled mechanical properties. Over the last years, the number of applications of these sensors has shown a fast growth in diverse fields, such as genomic or proteomic, because of the biosensor flexibility, the low sample consumption, and the non-pretreated samples required. In this chapter, we report a dedicated design and a fabrication process of highly sensitive microcantilever silicon sensors. We will describe as well an application of the device in the environmental field showing the immunodetection of an organic toxic pesticide as an example. The cantilever biofunctionalization process and the subsequent pesticide determination are detected in real time by monitoring the nanometer-scale bending of the microcantilever due to a differential surface stress generated between both surfaces of the device.

  18. Dual-Mode Electro-Optical Techniques for Biosensing Applications: A Review.

    PubMed

    Juan-Colás, José; Johnson, Steven; Krauss, Thomas F

    2017-09-07

    The monitoring of biomolecular interactions is a key requirement for the study of complex biological processes and the diagnosis of disease. Technologies that are capable of providing label-free, real-time insight into these interactions are of great value for the scientific and clinical communities. Greater understanding of biomolecular interactions alongside increased detection accuracy can be achieved using technology that can provide parallel information about multiple parameters of a single biomolecular process. For example, electro-optical techniques combine optical and electrochemical information to provide more accurate and detailed measurements that provide unique insights into molecular structure and function. Here, we present a comparison of the main methods for electro-optical biosensing, namely, electrochemical surface plasmon resonance (EC-SPR), electrochemical optical waveguide lightmode spectroscopy (EC-OWLS), and the recently reported silicon-based electrophotonic approach. The comparison considers different application spaces, such as the detection of low concentrations of biomolecules, integration, the tailoring of light-matter interaction for the understanding of biomolecular processes, and 2D imaging of biointeractions on a surface.

  19. Further evidence supporting the concurrent influence of aflatoxin and manganese

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katzen, J.S.; Llewellyn, G.C.

    Trace elements, including manganese may afford protection from deleterious effects of aflatoxin. Young male Fischer rats received ip injections of aflatoxin B1 (AFB1) in dimethyl sulfoxide (DMSO), 1 mg/kg, 2 mg/kg or 4 mg/kg. Control groups received DMSO ip or no injection. All animals were intubated with 3 microCi of (/sup 54/Mn)-MnCl/sub 2/ 12 hr post-injection. Sacrifice occurred 72 hr after gavage of the radiolabel. All tested levels of AFB1 affected the loss of total body radioactivity. This response was observed within 12 hr when toxin-treated groups excreted almost 4 times more counts than controls. From 12-36 hr following radiolabelmore » administration, AFB1 appeared to enhance excretion; by 72 hr, toxin-treated animals (especially those receiving higher doses) appeared to conserve the metal. Aflatoxicosis manifested itself through reduced body weight gain. The data provide support evidence that Mn and AFB1 biointeract.« less

  20. Comparative developmental toxicity of new aromatic halogenated DBPs in a chlorinated saline sewage effluent to the marine polychaete Platynereis dumerilii.

    PubMed

    Yang, Mengting; Zhang, Xiangru

    2013-10-01

    Using seawater for toilet flushing may introduce high levels of bromide and iodide into a city's sewage treatment works, and result in the formation of brominated and iodinated disinfection byproducts (DBPs) during chlorination to disinfect sewage effluents. In a previous study, the authors' group has detected the presence of many brominated DBPs and identified five new aromatic brominated DBPs in chlorinated saline sewage effluents. The presence of brominated DBPs in chlorinated saline effluents may pose adverse implications for marine ecology. In this study, besides the detection and identification of another seven new aromatic halogenated DBPs in a chlorinated saline sewage effluent, their developmental toxicity was evaluated using the marine polychaete Platynereis dumerilii. For comparison, the developmental toxicity of some commonly known halogenated DBPs was also examined. The rank order of the developmental toxicity of 20 halogenated DBPs was 2,5-dibromohydroquinone > 2,6-diiodo-4-nitrophenol ≥ 2,4,6-triiodophenol > 4-bromo-2-chlorophenol ≥ 4-bromophenol > 2,4-dibromophenol ≥ 2,6-dibromo-4-nitrophenol > 2-bromo-4-chlorophenol > 2,6-dichloro-4-nitrophenol > 2,4-dichlorophenol > 2,4,6-tribromophenol > 3,5-dibromo-4-hydroxybenzaldehyde > bromoform ≥ 2,4,6-trichlorophenol > 2,6-dibromophenol > 2,6-dichlorophenol > iodoacetic acid ≥ tribromoacetic acid > bromoacetic acid > chloroacetic acid. On the basis of developmental toxicity data, a quantitative structure-activity relationship (QSAR) was established. The QSAR involved two physical-chemical property descriptors (log P and pKa) and two electronic descriptors (the lowest unoccupied molecular orbital energy and the highest occupied molecular orbital energy) to indicate the transport, biouptake, and biointeraction of these DBPs. It can well predict the developmental toxicity of most of the DBPs tested.

  1. Use of entrapment and high-performance affinity chromatography to compare the binding of drugs and site-specific probes with normal and glycated human serum albumin

    PubMed Central

    Jackson, Abby J.; Anguizola, Jeanethe; Pfaunmiller, Erika L.; Hage, David S.

    2013-01-01

    Protein entrapment and high-performance affinity chromatography were used with zonal elution to examine the changes in binding that occurred for site-specific probes and various sulfonylurea drugs with normal and glycated forms of human serum albumin (HSA). Samples of this protein in a soluble form were physically entrapped within porous silica particles by using glycogen-capped hydrazide-activated silica; these supports were then placed into 1.0 cm × 2.1 mm inner diameter columns. Initial zonal elution studies were performed using (R)-warfarin and L-tryptophan as probes for Sudlow sites I and II (i.e., the major drug binding sites of HSA), giving quantitative measures of binding affinities in good agreement with literature values. It was also found for solutes with multisite binding to the same proteins, such as many sulfonylurea drugs, that this method could be used to estimate the global affinity of the solute for the entrapped protein. This entrapment and zonal approach provided retention information with precisions of ±0.1–3.3% (± one standard deviation) and elution within 0.50–3.00 min for solutes with binding affinities of 1 × 104–3 × 105 M−1. Each entrapped-protein column was used for many binding studies, which decreased the cost and amount of protein needed per injection (e.g., the equivalent of only 125–145 pmol of immobilized HSA or glycated HSA per injection over 60 sample application cycles). This method can be adapted for use with other proteins and solutes and should be valuable in high-throughput screening or quantitative studies of drug–protein binding or related biointeractions. PMID:23657448

  2. Studies on Bacterial Proteins Corona Interaction with Saponin Imprinted ZnO Nanohoneycombs and Their Toxic Responses.

    PubMed

    Sharma, Deepali; Ashaduzzaman, Md; Golabi, Mohsen; Shriwastav, Amritanshu; Bisetty, Krishna; Tiwari, Ashutosh

    2015-11-04

    Molecular imprinting generates robust, efficient, and highly mesoporous surfaces for biointeractions. Mechanistic interfacial interaction between the surface of core substrate and protein corona is crucial to understand the substantial microbial toxic responses at a nanoscale. In this study, we have focused on the mechanistic interactions between synthesized saponin imprinted zinc oxide nanohoneycombs (SIZnO NHs), average size 80-125 nm, surface area 20.27 m(2)/g, average pore density 0.23 pore/nm and number-average pore size 3.74 nm and proteins corona of bacteria. The produced SIZnO NHs as potential antifungal and antibacterial agents have been studied on Sclerotium rolfsii (S. rolfsii), Pythium debarynum (P. debarynum) and Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), respectively. SIZnO NHs exhibited the highest antibacterial (∼50%) and antifungal (∼40%) activity against Gram-negative bacteria (E. coli) and fungus (P. debarynum), respectively at concentration of 0.1 mol. Scanning electron spectroscopy (SEM) observation showed that the ZnO NHs ruptured the cell wall of bacteria and internalized into the cell. The molecular docking studies were carried out using binding proteins present in the gram negative bacteria (lipopolysaccharide and lipocalin Blc) and gram positive bacteria (Staphylococcal Protein A, SpA). It was envisaged that the proteins present in the bacterial cell wall were found to interact and adsorb on the surface of SIZnO NHs thereby blocking the active sites of the proteins used for cell wall synthesis. The binding affinity and interaction energies were higher in the case of binding proteins present in gram negative bacteria as compared to that of gram positive bacteria. In addition, a kinetic mathematical model (KMM) was developed in MATLAB to predict the internalization in the bacterial cellular uptake of the ZnO NHs for better understanding of their controlled toxicity. The results obtained from KMM exhibited a good agreement with the experimental data. Exploration of mechanistic interactions, as well as the formation of bioconjugate of proteins and ZnO NHs would play a key role to interpret more complex biological systems in nature.

  3. Industrial grade 2D molybdenum disulphide (MoS2): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation

    NASA Astrophysics Data System (ADS)

    Moore, Caroline; Movia, Dania; Smith, Ronan J.; Hanlon, Damien; Lebre, Filipa; Lavelle, Ed C.; Byrne, Hugh J.; Coleman, Jonathan N.; Volkov, Yuri; McIntyre, Jennifer

    2017-06-01

    The recent surge in graphene research, since its liquid phase monolayer isolation and characterization in 2004, has led to advancements which are accelerating the exploration of alternative 2D materials such as molybdenum disulphide (MoS2), whose unique physico-chemical properties can be exploited in applications ranging from cutting edge electronic devices to nanomedicine. However, to assess any potential impact on human health and the environment, the need to understand the bio-interaction of MoS2 at a cellular and sub-cellular level is critical. Notably, it is important to assess such potential impacts of materials which are produced by large scale production techniques, rather than research grade materials. The aim of this study was to explore cytotoxicity, cellular uptake and inflammatory responses in established cell-lines that mimic different potential exposure routes (inhalation, A549; ingestion, AGS; monocyte, THP-1) following incubation with MoS2 flakes of varying sizes (50 nm, 117 nm and 177 nm), produced by liquid phase exfoliation. Using high content screening (HCS) and Live/Dead assays, it was established that 1 µg ml-1 (for the three different MoS2 sizes) did not induce toxic effects on any of the cell-lines. Confocal microscopy images revealed a normal cellular morphology in all cases. Transmission electron microscopy (TEM) confirmed the uptake of all MoS2 nanomaterials in all the cell-lines, the MoS2 ultimately locating in single membrane vesicles. At such sub-lethal doses, inflammatory responses are observed, however, associated, at least partially, with the presence of lipopolysaccharide endotoxin in nanomaterial suspensions and surfactant samples. Therefore, the inflammatory response of the cells to the MoS2 or endotoxin contamination was interrogated using a 10-plex ELISA which illustrates cytokine production. The experiments carried out using wild-type and endotoxin hyporesponsive bone marrow derived dendritic cells confirmed that the inflammatory responses result from a combination of endotoxin contamination, the MoS2 nanomaterials themselves, and the stabilizing surfactant.

  4. Comprehensive characterization of well-defined silk fibroin surfaces: Toward multitechnique studies of surface modification effects.

    PubMed

    Amornsudthiwat, Phakdee; Nitschke, Mirko; Zimmermann, Ralf; Friedrichs, Jens; Grundke, Karina; Pöschel, Kathrin; Damrongsakkul, Siriporn; Werner, Carsten

    2015-06-21

    The study aims at a comprehensive surface characterization of untreated and oxygen plasma-treated silk fibroin with a particular focus on phenomena relevant to biointeraction and cell adhesion. For that purpose, a range of advanced surface diagnostic techniques is employed to thoroughly investigate well-defined and especially clean silk fibroin samples in a comparable setting. This includes surface chemistry and surface charges as factors, which control protein adsorption, but also hydration and swelling of the material as important parameters, which govern the mechanical stiffness at the interface with aqueous media. Oxygen plasma exposure of silk fibroin surfaces reveals that material ablation strongly predominates over the introduction of functional groups even for mild plasma conditions. A substantial increase in mechanical stiffness is identified as the most prominent effect upon this kind of plasma treatment. Regarding the experimental approach and the choice of techniques, the work goes beyond previous studies in this field and paves the way for well-founded investigations of other surface-selective modification procedures that enhance the applicability of silk fibroin in biomedical applications.

  5. Use of radiation in biomaterials science

    NASA Astrophysics Data System (ADS)

    Benson, Roberto S.

    2002-05-01

    Radiation is widely used in the biomaterials science for surface modification, sterilization and to improve bulk properties. Radiation is also used to design of biochips, and in situ photopolymerizable of bioadhesives. The energy sources most commonly used in the irradiation of biomaterials are high-energy electrons, gamma radiation, ultraviolet (UV) and visible light. Surface modification involves placement of selective chemical moieties on the surface of a material by chemical reactions to improve biointeraction for cell adhesion and proliferation, hemocompatibility and water absorption. The exposure of a polymer to radiation, especially ionizing radiation, can lead to chain scission or crosslinking with changes in bulk and surface properties. Sterilization by irradiation is designed to inactivate most pathogens from the surface of biomedical devices. An overview of the use of gamma and UV radiation to improve surface tissue compatibility, bulk properties and surface properties for wear resistance, formation of hydrogels and curing dental sealants and bone adhesives is presented. Gamma and vacuum ultraviolet (VUV) irradiated ultrahigh molecular weight polyethylene (UHMWPE) exhibit improvement in surface modulus and hardness. The surface modulus and hardness of UHMWPE showed a dependence on type of radiation, dosage and processing. VUV surface modified e-PTFE vascular grafts exhibit increases in hydrophilicity and improvement towards adhesion of fibrin glue.

  6. Affinity monolith chromatography: A review of principles and recent analytical applications

    PubMed Central

    Pfaunmiller, Erika L.; Paulemond, Marie Laura; Dupper, Courtney M.; Hage, David S.

    2012-01-01

    Affinity monolith chromatography (AMC) is a type of liquid chromatography that uses a monolithic support and a biologically-related binding agent as a stationary phase. AMC is a powerful method for the selective separation, analysis or studies of specific target compounds in a sample. This review discusses the basic principles of AMC and recent developments or applications of this method, with particular emphasis being given to work that has appeared in the last five years. Various materials that have been used to prepare columns for AMC are examined, including organic monoliths, silica monoliths, agarose monoliths and cryogels. These supports have been used in AMC for formats that have ranged from traditional columns to disks, microcolumns and capillaries. Many binding agents have also been employed in AMC, such as antibodies, enzymes, proteins, lectins, immobilized metal-ions and dyes. Some applications that have been reported with these binding agents in AMC are bioaffinity chromatography, immunoaffinity chromatography or immunoextraction, immobilized metal-ion affinity chromatography, dye-ligand affinity chromatography, chiral separations and biointeraction studies. Examples are presented from fields that include analytical chemistry, pharmaceutical analysis, clinical testing and biotechnology. Current trends and possible future directions in AMC are also discussed. PMID:23187827

  7. In vivo imaging and toxicity assessments of fluorescent nanodiamonds in Caenorhabditis elegans.

    PubMed

    Mohan, Nitin; Chen, Chao-Sheng; Hsieh, Hsiao-Han; Wu, Yi-Chun; Chang, Huan-Cheng

    2010-09-08

    Nanoscale carbon materials hold great promise for biotechnological and biomedical applications. Fluorescent nanodiamond (FND) is a recent new addition to members of the nanocarbon family. Here, we report long-term in vivo imaging of FNDs in Caenorhabditis elegans (C. elegans) and explore the nano-biointeractions between this novel nanomaterial and the model organism. FNDs are introduced into wild-type C. elegans by either feeding them with colloidal FND solution or microinjecting FND suspension into the gonads of the worms. On feeding, bare FNDs stay in the intestinal lumen, while FNDs conjugated with biomolecules (such as dextran and bovine serum albumin) are absorbed into the intestinal cells. On microinjection, FNDs are dispersed in the gonad and delivered to the embryos and eventually into the hatched larvae in the next generation. The toxicity assessments, performed by employing longevity and reproductive potential as physiological indicators and measuring stress responses with use of reporter genes, show that FNDs are stable and nontoxic and do not cause any detectable stress to the worms. The high brightness, excellent photostability, and nontoxic nature of the nanomaterial have enabled continuous imaging of the whole digestive system and tracking of the cellular and developmental processes of the living organism for several days.

  8. Development of Formaldehyde Biosensor for Determination of Formalin in Fish Samples; Malabar Red Snapper (Lutjanus malabaricus) and Longtail Tuna (Thunnus tonggol)

    PubMed Central

    Noor Aini, Bohari; Siddiquee, Shafiquzzaman; Ampon, Kamaruzaman

    2016-01-01

    Electrochemical biosensors are widely recognized in biosensing devices due to the fact that gives a direct, reliable, and reproducible measurement within a short period. During bio-interaction process and the generation of electrons, it produces electrochemical signals which can be measured using an electrochemical detector. A formaldehyde biosensor was successfully developed by depositing an ionic liquid (IL) (e.g., 1-ethyl-3-methylimidazolium trifluoromethanesulfonate ([EMIM][Otf])), gold nanoparticles (AuNPs), and chitosan (CHIT), onto a glassy carbon electrode (GCE). The developed formaldehyde biosensor was analyzed for sensitivity, reproducibility, storage stability, and detection limits. Methylene blue was used as a redox indicator for increasing the electron transfer in the electrochemical cell. The developed biosensor measured the NADH electron from the NAD+ reduction at a potential of 0.4 V. Under optimal conditions, the differential pulse voltammetry (DPV) method detected a wider linear range of formaldehyde concentrations from 0.01 to 10 ppm within 5 s, with a detection limit of 0.1 ppm. The proposed method was successfully detected with the presence of formalin in fish samples, Lutjanus malabaricus and Thunnus Tonggol. The proposed method is a simple, rapid, and highly accurate, compared to the existing technique. PMID:27376338

  9. 78 FR 74154 - Draft Guidance for Industry on Size, Shape, and Other Physical Attributes of Generic Tablets and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    ...] Draft Guidance for Industry on Size, Shape, and Other Physical Attributes of Generic Tablets and... ``Size, Shape, and Other Physical Attributes of Generic Tablets and Capsules.'' This guidance discusses FDA recommendations for the size, shape, and other physical attributes of generic tablets intended to...

  10. The Size Congruity Effect: Is Bigger Always More?

    ERIC Educational Resources Information Center

    Santens, Seppe; Verguts, Tom

    2011-01-01

    When comparing digits of different physical sizes, numerical and physical size interact. For example, in a numerical comparison task, people are faster to compare two digits when their numerical size (the relevant dimension) and physical size (the irrelevant dimension) are congruent than when they are incongruent. Two main accounts have been put…

  11. Conceptual size in developmental dyscalculia and dyslexia.

    PubMed

    Gliksman, Yarden; Henik, Avishai

    2018-02-01

    People suffering from developmental dyscalculia (DD) are known to have impairment in numerical abilities and have been found to have weaker processing of countable magnitudes. However, not much research was done on their abilities to process noncountable magnitudes. An example of noncountable magnitude is conceptual size (e.g., mouse is small and elephant is big). Recently, we found that adults process conceptual size automatically. The current study examined automatic processing of conceptual size in students with DD and developmental dyslexia. Conceptual and physical sizes were manipulated orthogonally to create congruent (e.g., a physically small apple compared to a physically large violin) and incongruent (e.g., a physically large apple compared to a physically small violin) conditions. Participants were presented with 2 objects and had to choose the larger one. Each trial began with an instruction to respond to the physical or to the conceptual dimension. Control and the dyslexic groups presented automatic processing of both conceptual and physical sizes. The dyscalculic group presented automatic processing of physical size but not automaticity of processing conceptual size. Our results fit with previous findings of weaker magnitude representation in those with DD, specifically regarding noncountable magnitudes, and support theories of a shared neurocognitive substrate for different types of magnitudes. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  12. An exploratory study of the association between physical activity, cardiovascular fitness and body size in children with Down syndrome.

    PubMed

    Shields, Nora; Hussey, Juliette; Murphy, Joan; Gormley, John; Hoey, Hilary

    2017-02-01

    To explore the association between physical activity, cardiovascular fitness and body size among children with Down syndrome. Physical activity, cardiovascular fitness and body size were measured by accelerometry, maximal fitness test and anthropometric measurements (BMI, waist circumference), respectively. Fourteen children with Down syndrome (8 boys, 6 girls; mean age 12.9 years) participated. There was no significant correlation between physical activity and cardiovascular fitness or physical activity and body size. Children with Down syndrome who were fitter, had lower BMIs (r = -0.77, 95% confidence interval (CI) -0.41 to -0.93) and smaller waist circumference (r = -0.75, 95% CI -0.36 to -0.92). Preliminary evidence suggests physical activity may not be associated with either body size or fitness in children with Down syndrome. Body size appears to be inversely related to fitness in children with Down syndrome.

  13. The association between global self-esteem, physical self-concept and actual vs ideal body size rating in Chinese primary school children.

    PubMed

    Lau, P W C; Lee, A; Ransdell, L; Yu, C W; Sung, R Y T

    2004-02-01

    To investigate whether the discrepancy between actual and ideal body size rating is related to Chinese children's global self-esteem and global physical self-concept. A cross-sectional study of school children who completed questionnaires related to global self-esteem, global physical self-concept, and actual vs ideal body size. A total of 386 Chinese children (44% girls and 56% boys) aged 7-13 y from a primary school in Hong Kong, China. Global self-esteem and physical self-concept were measured using the physical self-descriptive questionnaire. Actual vs ideal body size discrepancy was established using the silhouette matching task. No significant relationship was found between global self-esteem and actual-ideal body size discrepancy of children. Global physical self-concept had a moderate negative correlation (r=-0.12) with the body size discrepancy score and the discrepancy score explained very limited variance (R(2)=0.015; F(1, 296)=4.51; P<0.05) in global physical self-concept. Three body size discrepancy groups (none, positive, and negative) were examined to see if there were any significant differences in global self-esteem, global physical self-concept, and specific dimensions of physical self-concept. A significant overall difference was found between groups for global physical self-concept (F=3.73, P<0.05) and the physical self-concept subscales of physical activity (F=3.25, P<0.05), body fat (F=61.26, P<0.001), and strength (F=5.26, P<0.01). Boys scored significantly higher than girls on global physical self-concept-especially in the sport competence, strength, and endurance subscales. This study revealed that the actual-ideal body size discrepancy rating of Chinese children was not predictive of global physical self-concept and global self-esteem. These findings are contrary to those reported in Western children, which may mean that culture plays a role in the formation of body attitude.

  14. Interaction between numbers and size during visual search.

    PubMed

    Krause, Florian; Bekkering, Harold; Pratt, Jay; Lindemann, Oliver

    2017-05-01

    The current study investigates an interaction between numbers and physical size (i.e. size congruity) in visual search. In three experiments, participants had to detect a physically large (or small) target item among physically small (or large) distractors in a search task comprising single-digit numbers. The relative numerical size of the digits was varied, such that the target item was either among the numerically large or small numbers in the search display and the relation between numerical and physical size was either congruent or incongruent. Perceptual differences of the stimuli were controlled by a condition in which participants had to search for a differently coloured target item with the same physical size and by the usage of LCD-style numbers that were matched in visual similarity by shape transformations. The results of all three experiments consistently revealed that detecting a physically large target item is significantly faster when the numerical size of the target item is large as well (congruent), compared to when it is small (incongruent). This novel finding of a size congruity effect in visual search demonstrates an interaction between numerical and physical size in an experimental setting beyond typically used binary comparison tasks, and provides important new evidence for the notion of shared cognitive codes for numbers and sensorimotor magnitudes. Theoretical consequences for recent models on attention, magnitude representation and their interactions are discussed.

  15. Paying attention to attention: evidence for an attentional contribution to the size congruity effect.

    PubMed

    Risko, Evan F; Maloney, Erin A; Fugelsang, Jonathan A

    2013-08-01

    Understanding the mechanisms supporting our comprehension of magnitude information represents a key goal in cognitive psychology. A major phenomenon employed in the pursuit of this goal has been the physical size congruity effect-namely, the observation that comparing the relative numerical sizes of two numbers is influenced by their relative physical sizes. The standard account of the physical size congruity effect attributes it to the automatic influence of the comparison of irrelevant physical magnitudes on numerical judgments. Here we develop an alternative account of this effect on the basis of the operation of attention in the typical size congruity display and the temporal dynamics of number comparison. We also provide a test of a number of predictions derived from this alternative account by combining a physical size congruity manipulation with a manipulation designed to alter the operation of attention within the typical size congruity display (i.e., a manipulation of the relative onsets of the digits). This test provides evidence consistent with an attentional contribution to the size congruity effect. Implications for our understanding of magnitude and the interactions between attention and magnitude are discussed.

  16. Investigation of interactions of Comtan with human serum albumin by mathematically modeled voltammetric data: A study from bio-interaction to biosensing.

    PubMed

    Jalalvand, Ali R; Ghobadi, Sirous; Goicoechea, Hector C; Gu, Hui-Wen; Sanchooli, Esmael

    2018-05-16

    In this work, voltammetric data recorded at a glassy carbon electrode (GCE) were separately used to investigate the interactions of entacapone (Comtan, CAT) with human serum albumin (HSA). Then, an augmented data matrix was constructed by the combination of voltammetric and spectroscopic data and simultaneously analysed by multivariate curve resolution-alternating least squares (MCR-ALS) to obtain more information about CAT-HSA interactions. The absence of rotational ambiguities in results obtained by MCR-ALS was verified with the help of MCR-BANDS and we confirmed that the results were unambiguous and reliable. Binding of CAT to HSA was also modeled by molecular docking and the results were compatible with those of obtained by recording experimental data. Hard-modeling of combined voltammetric and spectroscopic data by EQUISPEC as an efficient chemometric algorithm helped us to compute binding constant of CAT-HSA complex specie which was in a good agreement with the binding constant value obtained by direct analysis of experimental data. For electrochemical sensing of serum albumin two amperometric measurements were performed to determine HSA in 2-27 nM and 27-70 nM with a limit of detection of 0.51 nM and a sensitivity of 1.84 μA nM -1 . Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Body size satisfaction and physical activity levels among men and women.

    PubMed

    Kruger, Judy; Lee, Chong-Do; Ainsworth, Barbara E; Macera, Caroline A

    2008-08-01

    Body size satisfaction may be an important factor associated with physical activity. We analyzed data from the 2002 National Physical Activity and Weight Loss Survey (NPAWLS), a population-based cross-sectional telephone survey of US adults. Multiple logistic regression models were used to examine the association of body size satisfaction on being regularly active. Participants were aged > or =18 years with complete data on weight, race/ethnicity, physical activity level, and body size satisfaction (n = 10,021). More than half of men (55.8%) and women (53.3%) who reported being very satisfied with the body size were regularly active. After adjustment for covariates, participants who reported being somewhat or not satisfied with their body size had a 13 and 44% lower odds of being regularly active, respectively, compared with those very satisfied with their body size. When stratified by race/ethnicity, this association remained in whites (P for trend <0.001), but became weaker and nonsignificant in blacks, Hispanics, or other racial/ethnic groups. Irrespective of actual weight, those who were satisfied with their body size were more likely to engage in regular physical activity than those less satisfied. Further research is needed to explore predictors of physical activity to reduce health disparities.

  18. Bottom-up and top-down attentional contributions to the size congruity effect.

    PubMed

    Sobel, Kenith V; Puri, Amrita M; Faulkenberry, Thomas J

    2016-07-01

    The size congruity effect refers to the interaction between the numerical and physical (i.e., font) sizes of digits in a numerical (or physical) magnitude selection task. Although various accounts of the size congruity effect have attributed this interaction to either an early representational stage or a late decision stage, only Risko, Maloney, and Fugelsang (Attention, Perception, & Psychophysics, 75, 1137-1147, 2013) have asserted a central role for attention. In the present study, we used a visual search paradigm to further study the role of attention in the size congruity effect. In Experiments 1 and 2, we showed that manipulating top-down attention (via the task instructions) had a significant impact on the size congruity effect. The interaction between numerical and physical size was larger for numerical size comparison (Exp. 1) than for physical size comparison (Exp. 2). In the remaining experiments, we boosted the feature salience by using a unique target color (Exp. 3) or by increasing the display density by using three-digit numerals (Exps. 4 and 5). As expected, a color singleton target abolished the size congruity effect. Searching for three-digit targets based on numerical size (Exp. 4) resulted in a large size congruity effect, but search based on physical size (Exp. 5) abolished the effect. Our results reveal a substantial role for top-down attention in the size congruity effect, which we interpreted as support for a shared-decision account.

  19. Visual search for conjunctions of physical and numerical size shows that they are processed independently.

    PubMed

    Sobel, Kenith V; Puri, Amrita M; Faulkenberry, Thomas J; Dague, Taylor D

    2017-03-01

    The size congruity effect refers to the interaction between numerical magnitude and physical digit size in a symbolic comparison task. Though this effect is well established in the typical 2-item scenario, the mechanisms at the root of the interference remain unclear. Two competing explanations have emerged in the literature: an early interaction model and a late interaction model. In the present study, we used visual conjunction search to test competing predictions from these 2 models. Participants searched for targets that were defined by a conjunction of physical and numerical size. Some distractors shared the target's physical size, and the remaining distractors shared the target's numerical size. We held the total number of search items fixed and manipulated the ratio of the 2 distractor set sizes. The results from 3 experiments converge on the conclusion that numerical magnitude is not a guiding feature for visual search, and that physical and numerical magnitude are processed independently, which supports a late interaction model of the size congruity effect. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  20. Accuracy of Physical Examination, Ultrasonography, and Mammography in Predicting Residual Pathologic Tumor Size in Patients Treated With Neoadjuvant Chemotherapy

    PubMed Central

    Chagpar, Anees B.; Middleton, Lavinia P.; Sahin, Aysegul A.; Dempsey, Peter; Buzdar, Aman U.; Mirza, Attiqa N.; Ames, Fredrick C.; Babiera, Gildy V.; Feig, Barry W.; Hunt, Kelly K.; Kuerer, Henry M.; Meric-Bernstam, Funda; Ross, Merrick I.; Singletary, S Eva

    2006-01-01

    Objective: To assess the accuracy of physical examination, ultrasonography, and mammography in predicting residual size of breast tumors following neoadjuvant chemotherapy. Background: Neoadjuvant chemotherapy is an accepted part of the management of stage II and III breast cancer. Accurate prediction of residual pathologic tumor size after neoadjuvant chemotherapy is critical in guiding surgical therapy. Although physical examination, ultrasonography, and mammography have all been used to predict residual tumor size, there have been conflicting reports about the accuracy of these methods in the neoadjuvant setting. Methods: We reviewed the records of 189 patients who participated in 1 of 2 protocols using doxorubicin-containing neoadjuvant chemotherapy, and who had assessment by physical examination, ultrasonography, and/or mammography no more than 60 days before their surgical resection. Size correlations were performed using Spearman rho analysis. Clinical and pathologic measurements were also compared categorically using the weighted kappa statistic. Results: Size estimates by physical examination, ultrasonography, and mammography were only moderately correlated with residual pathologic tumor size after neoadjuvant chemotherapy (correlation coefficients: 0.42, 0.42, and 0.41, respectively), with an accuracy of ±1 cm in 66% of patients by physical examination, 75% by ultrasonography, and 70% by mammography. Kappa values (0.24–0.35) indicated poor agreement between clinical and pathologic measurements. Conclusion: Physical examination, ultrasonography, and mammography were only moderately useful for predicting residual pathologic tumor size after neoadjuvant chemotherapy. PMID:16432360

  1. Correlates of Physical Functioning and Performance Across the Spectrum of Kidney Function.

    PubMed

    Segura-Ortí, E; Gordon, P L; Doyle, J W; Johansen, K L

    2018-06-01

    The aim of this study was to determine the extent to which poor physical functioning, low participation in physical activity, and muscle atrophy observed among patients on hemodialysis are evident in the earlier stages of chronic kidney disease (CKD). We enrolled adults in three groups: no CKD, Stages 3 to 4 CKD, and hemodialysis. Outcomes measured were physical activity, muscle size, thigh muscle strength, physical performance, and self-reported physical function. Patients with CKD had muscle area intermediate between the no CKD and hemodialysis groups, but they had low levels of physical activity that were similar to the hemodialysis group. Physical activity and muscle size were significantly associated with all outcomes. Kidney function was not significantly associated with muscle strength or physical performance after adjustment for physical activity and muscle size. In conclusion, interventions aimed to increase muscle mass and energy expenditure might have an impact on improving physical function of CKD patients.

  2. Physical pretreatment – woody biomass size reduction – for forest biorefinery

    Treesearch

    J.Y. Zhu

    2011-01-01

    Physical pretreatment of woody biomass or wood size reduction is a prerequisite step for further chemical or biochemical processing in forest biorefinery. However, wood size reduction is very energy intensive which differentiates woody biomass from herbaceous biomass for biorefinery. This chapter discusses several critical issues related to wood size reduction: (1)...

  3. The chemical environment of iron in mineral fibres. A combined X-ray absorption and Mössbauer spectroscopic study.

    PubMed

    Pollastri, Simone; D'Acapito, Francesco; Trapananti, Angela; Colantoni, Ivan; Andreozzi, Giovanni B; Gualtieri, Alessandro F

    2015-11-15

    Although asbestos represents today one of the most harmful contaminant on Earth, in 72% of the countries worldwide only amphiboles are banned while controlled use of chrysotile is allowed. Uncertainty on the potential toxicity of chrysotile is due to the fact that the mechanisms by which mineral fibres induces cyto- and geno-toxic damage are still unclear. We have recently started a long term project aimed at the systematic investigation of the crystal-chemistry, bio-interaction and toxicity of the mineral fibres. This work presents a systematic structural investigation of iron in asbestos and erionite (considered the most relevant mineral fibres of social and/or economic-industrial importance) using synchrotron X-ray absorption and Mössbauer spectroscopy. In all investigated mineral fibres, iron in the bulk structure is found in octahedral sites and can be made available at the surface via fibre dissolution. We postulate that the amount of hydroxyl radicals released by the fibers depends, among other factors, upon their dissolution rate; in relation to this, a ranking of ability of asbestos fibres to generate hydroxyl radicals, resulting from available surface iron, is advanced: amosite > crocidolite ≈ chrysotile > anthophyllite > tremolite. Erionite, with a fairly high toxicity potential, contains only octahedrally coordinated Fe(3+). Although it needs further experimental evidence, such available surface iron may be present as oxide nanoparticles coating and can be a direct cause of generation of hydroxyl radicals when such coating dissolves. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. The influence of maturation, body size and physical self-perceptions on longitudinal changes in physical activity in adolescent girls.

    PubMed

    Fawkner, Samantha; Henretty, Joan; Knowles, Ann-Marie; Nevill, Alan; Niven, Ailsa

    2014-01-01

    The aim of this study was to adopt a longitudinal design to explore the direct effects of both absolute and relative maturation and changes in body size on physical activity, and explore if, and how, physical self-perceptions might mediate this effect. We recruited 208 girls (11.8 ± 0.4 years) at baseline. Data were collected at three subsequent time points, each 6 months apart. At 18 months, 119 girls remained in the study. At each time point, girls completed the Physical Activity Questionnaire for Children, the Pubertal Development Scale (from which, both a measure of relative and absolute maturation were defined) and the Physical Self-Perception Profile, and had physical size characteristics assessed. Multilevel modelling for physical activity indicated a significant negative effect of age, positive effect for physical condition and sport competence and positive association for relatively early maturers. Absolute maturation, body mass, waist circumference and sum of skinfolds did not significantly contribute to the model. Contrary to common hypotheses, relatively more mature girls may, in fact, be more active than their less mature peers. However, neither changes in absolute maturation nor physical size appear to directly influence changes in physical activity in adolescent girls.

  5. The Surface-to-Volume Ratio in Thermal Physics: From Cheese Cube Physics to Animal Metabolism

    ERIC Educational Resources Information Center

    Planinsic, Gorazd; Vollmer, Michael

    2008-01-01

    The surface-to-volume ratio is an important quantity in thermal physics. For example it governs the behaviour of heating or cooling of physical objects as a function of size like, e.g. cubes or spheres made of different material. The starting point in our paper is the simple physics problem of how cheese cubes of different sizes behave if heated…

  6. Cohort Size, Sex and Socio-Economic Status as Predictors of Success in Year 12 Physics in Perth, 1987-1997

    ERIC Educational Resources Information Center

    Geelan, David; Louden, William; Wildy, Helen

    2013-01-01

    A variety of factors are associated with students' achievement in secondary school physics, including cohort size--the total number of students studying Physics in the school--and socioeconomic status. Earlier studies also showed boys achieving better in Physics, while more recent research has shown better results for girls. Statistical analysis…

  7. Physics and Size in Biological Systems.

    ERIC Educational Resources Information Center

    Barnes, George

    1989-01-01

    Described is the subject of biological scaling for physics teachers including examples and in-depth reading. Topics are elements of scaling, terminal velocities, Lilliputian and Brobdingnagian, brain evolution, dolphin echolocation, surface tension, gravity change, food and oxygen, and seeing. Ten references on physics and size, and ten questions…

  8. Effect of specimen size and grain orientation on the mechanical and physical properties of NBG-18 nuclear graphite

    DOE PAGES

    Vasudevamurthy, G.; Byun, T. S.; Pappano, Pete; ...

    2015-03-13

    Here we present a comparison of the measured baseline mechanical and physical properties of with grain (WG) and against grain (AG) non-ASTM size NBG-18 graphite. The objectives of the experiments were twofold: (1) assess the variation in properties with grain orientation; (2) establish a correlation between specimen tensile strength and size. The tensile strength of the smallest sized (4 mm diameter) specimens were about 5% higher than the standard specimens (12 mm diameter) but still within one standard deviation of the ASTM specimen size indicating no significant dependence of strength on specimen size. The thermal expansion coefficient and elastic constantsmore » did not show significant dependence on specimen size. Lastly, experimental data indicated that the variation of thermal expansion coefficient and elastic constants were still within 5% between the different grain orientations, confirming the isotropic nature of NBG-18 graphite in physical properties.« less

  9. Modelling the physical properties of glasslike carbon foams

    NASA Astrophysics Data System (ADS)

    Letellier, M.; Macutkevic, J.; Bychanok, D.; Kuzhir, P.; Delgado-Sanchez, C.; Naguib, H.; Ghaffari Mosanenzadeh, S.; Fierro, V.; Celzard, A.

    2017-07-01

    In this work, model alveolar materials - carbon cellular and/or carbon reticulated foams - were produced in order to study and to model their physical properties. It was shown that very different morphologies could be obtained whereas the constituting vitreous carbon from which they were made remained exactly the same. Doing so, the physical properties of these foams were expected to depend neither on the composition nor on the carbonaceous texture but only on the porous structure, which could be tuned for the first time for having a constant pore size in a range of porosities, or a range of pore sizes at fixed porosity. The physical properties were then investigated through mechanical, acoustic, thermal and electromagnetic measurements. The results demonstrate the roles played by bulk density and cell size on all physical properties. Whereas some of the latter strongly depend on porosity and/or pore size, others are independent of pore size. It is expected that these results apply to many other kinds of rigid foams used in a broad range of different applications. The present results therefore open the route to their optimisation.

  10. Children and Adults Use Physical Size and Numerical Alliances in Third-Party Judgments of Dominance.

    PubMed

    Lourenco, Stella F; Bonny, Justin W; Schwartz, Bari L

    2015-01-01

    Humans and other social animals interact regularly with conspecifics as part of affiliative groups. Many of these interactions are cooperative, but many others involve competition for resources. Competitive exchanges are often resolved on the basis of dominance relationships, with higher-ranking individuals receiving priority access to desired goods. Although no single cue can establish permanent dominance relationships, there are some cues that predict dominance fairly reliably across context. In the present study, we focused on two such cues relevant to competing groups: (i) the physical sizes of individual members, and (ii) their relative number. Using a social competition task, we examined whether, and how, preschool-aged children and adults used differences in physical size and numerical alliances to judge which of two groups should prevail in a competitive exchange for a desired object. These judgments were made when either physical size or number differed between groups (Experiment 1), and when both were available but pitted against each other (Experiments 1 and 2). Our findings revealed that by 3 years of age, humans use multiple perceptible cues in third-party judgments of dominance. Our findings also revealed that 3-year-olds, like adults, weighted these cues flexibly according to the additional factor of overall group size, with the physical sizes of individuals determining dominance in smaller groups (e.g., 2 vs. 4 characters) and the relative number of individuals determining dominance in larger groups (e.g., 15 vs. 30 characters). Taken together, our findings suggest that a basic formula for determining dominance in competitive exchanges, which weights physical size of individuals and numerical alliances as a function of overall group size, is available to young children and appears fairly stable through to adulthood.

  11. Factors associated with participation in physical activity among adolescents in Malaysia.

    PubMed

    Cheah, Yong Kang; Lim, Hock Kuang; Kee, Chee Cheong; Ghazali, Sumarni Mohd

    2016-11-01

    The rising prevalence of non-communicable diseases (NCDs) has become a serious public health issue. Among the multi-factorial drivers behind NCDs are modifiable health risk factors, most notably, physical inactivity. In response to the nearly global policy priority of encouraging regular participation in physical activity, the objective of the present study is to examine the factors that determine participation in physical activity among Malaysian adolescents. Nationally representative data consisting of a large sample size was used. A censored regression model was developed to estimate the likelihood of participation and time spent on physical activity. There are significant relationships between physical activity and gender, ethnicity, self-rated academic performance, maternal education, household size and time spent on physical education. The present study provides new insights into the factors affecting physical activity participation among adolescents. Specifically, self-rated excellent academic performance, household size and physical education can increase the likelihood of being physically active. Evidence of the present study implies that policy makers should pay special attention to females, Chinese, adolescents with self-rated poor academic performance and adolescents who have low maternal education.

  12. QUANTIFYING STREAM STRUCTURAL PHYSICAL HABITAT ATTRIBUTES USING LIDAR AND HYPERSPECTRAL IMAGERY

    EPA Science Inventory

    Structural physical habitat attributes include indices of stream size, channel gradient, substrate size, habitat complexity and cover, riparian vegetation cover and structure, anthropogenic disturbances and channel-riparian interaction.

  13. Interocular induction of illusory size perception.

    PubMed

    Song, Chen; Schwarzkopf, D Samuel; Rees, Geraint

    2011-03-11

    The perceived size of objects not only depends on their physical size but also on the surroundings in which they appear. For example, an object surrounded by small items looks larger than a physically identical object surrounded by big items (Ebbinghaus illusion), and a physically identical but distant object looks larger than an object that appears closer in space (Ponzo illusion). Activity in human primary visual cortex (V1) reflects the perceived rather than the physical size of objects, indicating an involvement of V1 in illusory size perception. Here we investigate the role of eye-specific signals in two common size illusions in order to provide further information about the mechanisms underlying illusory size perception. We devised stimuli so that an object and its spatial context associated with illusory size perception could be presented together to one eye or separately to two eyes. We found that the Ponzo illusion had an equivalent magnitude whether the objects and contexts were presented to the same or different eyes, indicating that it may be largely mediated by binocular neurons. In contrast, the Ebbinghaus illusion became much weaker when objects and their contexts were presented to different eyes, indicating important contributions to the illusion from monocular neurons early in the visual pathway. Our findings show that two well-known size illusions - the Ponzo illusion and the Ebbinghaus illusion - are mediated by different neuronal populations, and suggest that the underlying neural mechanisms associated with illusory size perception differ and can be dependent on monocular channels in the early visual pathway.

  14. Improved cardiovascular diagnostic accuracy by pocket size imaging device in non-cardiologic outpatients: the NaUSiCa (Naples Ultrasound Stethoscope in Cardiology) study

    PubMed Central

    2010-01-01

    Miniaturization has evolved in the creation of a pocket-size imaging device which can be utilized as an ultrasound stethoscope. This study assessed the additional diagnostic power of pocket size device by both experts operators and trainees in comparison with physical examination and its appropriateness of use in comparison with standard echo machine in a non-cardiologic population. Three hundred four consecutive non cardiologic outpatients underwent a sequential assessment including physical examination, pocket size imaging device and standard Doppler-echo exam. Pocket size device was used by both expert operators and trainees (who received specific training before the beginning of the study). All the operators were requested to give only visual, qualitative insights on specific issues. All standard Doppler-echo exams were performed by expert operators. One hundred two pocket size device exams were performed by experts and two hundred two by trainees. The time duration of the pocket size device exam was 304 ± 117 sec. Diagnosis of cardiac abnormalities was made in 38.2% of cases by physical examination and in 69.7% of cases by physical examination + pocket size device (additional diagnostic power = 31.5%, p < 0.0001). The overall K between pocket size device and standard Doppler-echo was 0.67 in the pooled population (0.84 by experts and 0.58 by trainees). K was suboptimal for trainees in the eyeball evaluation of ejection fraction, left atrial dilation and right ventricular dilation. Overall sensitivity was 91% and specificity 76%. Sensitivity and specificity were lower in trainees than in experts. In conclusion, pocket size device showed a relevant additional diagnostic value in comparison with physical examination. Sensitivity and specificity were good in experts and suboptimal in trainees. Specificity was particularly influenced by the level of experience. Training programs are needed for pocket size device users. PMID:21110840

  15. The visual perception of spatial extent.

    DOT National Transportation Integrated Search

    1963-09-01

    This study was concerned with the manner in which perceived depth and perceived frontoparallel size varied with physical distance and hence with each other. An equation expressing the relation between perceived frontoparallel size and physical depth ...

  16. Effect of Team Size in Soccer on Moderate to Vigorous Physical Activity

    ERIC Educational Resources Information Center

    Arnett, Mark G.

    2004-01-01

    The purpose of this study was to compare the percentages of moderate to vigorous physical activity (MVPA) in soccer games with different team sizes. Twenty-two university physical education majors evenly divided between males and females volunteered for the study. Students were blind to the purpose of the study. Data were collected over three…

  17. QUANTIFYING STRUCTURAL PHYSICAL HABITAT ATTRIBUTES USING LIDAR AND HYPERSPECTRAL IMAGERY

    EPA Science Inventory

    Structural physical habitat attributes include indices of stream size, channel gradient, substrate size, habitat complexity and cover, riparian vegetation cover and structure, anthropogenic disturbances and channel-riparian interaction. These habitat attributes will vary dependen...

  18. Plantar Fibroma

    MedlinePlus

    ... size. Orthotic devices. If the fibroma is stable, meaning it is not changing in size, custom orthotic devices (shoe inserts) may relieve the pain by distributing the patient’s weight away from the fibroma. Physical therapy. The pain is sometimes treated through physical ...

  19. The surface-to-volume ratio in thermal physics: from cheese cube physics to animal metabolism

    NASA Astrophysics Data System (ADS)

    Planinšič, Gorazd; Vollmer, Michael

    2008-03-01

    The surface-to-volume ratio is an important quantity in thermal physics. For example it governs the behaviour of heating or cooling of physical objects as a function of size like, e.g. cubes or spheres made of different material. The starting point in our paper is the simple physics problem of how cheese cubes of different sizes behave if heated either in a conventional oven or in a microwave oven. The outcome of these experiments depends on a balance between heating and cooling with the surface-to-volume ratio (S/V) as the key parameter. The role of (S/V) becomes most obvious in studying cooling curves of differently sized objects like cubes or spheres, alone. Besides problems in thermal physics, the surface-to-volume ratio has many important applications in biochemistry, chemistry and biology. It allows us to draw general conclusions concerning the thermal and mechanical properties of different-sized animals, in particular their metabolism. Hence, this topic offers rich contexts for interdisciplinary teaching. An example presented in this paper starts in physics while studying thermal properties of cheese cubes and ends up in biology by discussing the differences in food intake of animals from small mice to huge elephants.

  20. Source and Size of Emotional and Financial-Related Social Support Network on Physical Activity Behavior Among Older Adults.

    PubMed

    Loprinzi, Paul D; Joyner, Chelsea

    2016-07-01

    To examine the association of source of emotional- and financial-related social support and size of social support network on physical activity behavior among older adults. Data from the 1999-2006 NHANES were used (N = 5616; 60 to 85 yrs). Physical activity and emotional- and financial-related social support were assessed via self-report. Older adults with perceived having emotional social support had a 41% increased odds of meeting physical activity guidelines (OR = 1.41; 95% CI: 1.01-1.97). The only specific sources of social support that were associated with meeting physical activity guidelines was friend emotional support (OR = 1.19; 95% CI: 1.01-1.41) and financial support (OR = 1.28; 95% CI: 1.09-1.49). With regard to size of social support network, a dose-response relationship was observed. Compared with those with 0 close friends, those with 1 to 2, 3 to 4, 5, and 6+ close friends, respectively, had a 1.70-, 2.38-, 2.57-, and 2.71-fold increased odds of meeting physical activity guidelines. There was some evidence of gender- and age-specific associations between social support and physical activity. Emotional- and financial-related social support and size of social support network are associated with higher odds of meeting physical activity guidelines among older adults.

  1. Effects of Varying Team Sizes on Physical Activity Levels of College Students

    ERIC Educational Resources Information Center

    Gaudreault, Karen Lux; Cluphf, David; Russell, Jared; Lecheminant, James

    2014-01-01

    The purpose of this exploratory study was to examine physical activity levels among various team sizes for basketball and soccer in a C/UIPAP setting. Twenty-eight university physical education majors participated in the study. Participants engaged in three-on-three and five-on-five basketball and five-on-five and 11-on-11 soccer games. All games…

  2. Interocular induction of illusory size perception

    PubMed Central

    2011-01-01

    Background The perceived size of objects not only depends on their physical size but also on the surroundings in which they appear. For example, an object surrounded by small items looks larger than a physically identical object surrounded by big items (Ebbinghaus illusion), and a physically identical but distant object looks larger than an object that appears closer in space (Ponzo illusion). Activity in human primary visual cortex (V1) reflects the perceived rather than the physical size of objects, indicating an involvement of V1 in illusory size perception. Here we investigate the role of eye-specific signals in two common size illusions in order to provide further information about the mechanisms underlying illusory size perception. Results We devised stimuli so that an object and its spatial context associated with illusory size perception could be presented together to one eye or separately to two eyes. We found that the Ponzo illusion had an equivalent magnitude whether the objects and contexts were presented to the same or different eyes, indicating that it may be largely mediated by binocular neurons. In contrast, the Ebbinghaus illusion became much weaker when objects and their contexts were presented to different eyes, indicating important contributions to the illusion from monocular neurons early in the visual pathway. Conclusions Our findings show that two well-known size illusions - the Ponzo illusion and the Ebbinghaus illusion - are mediated by different neuronal populations, and suggest that the underlying neural mechanisms associated with illusory size perception differ and can be dependent on monocular channels in the early visual pathway. PMID:21396093

  3. Relationships between media use, body fatness and physical activity in children and youth: a meta-analysis.

    PubMed

    Marshall, S J; Biddle, S J H; Gorely, T; Cameron, N; Murdey, I

    2004-10-01

    To review the empirical evidence of associations between television (TV) viewing, video/computer game use and (a) body fatness, and (b) physical activity. Meta-analysis. Published English-language studies were located from computerized literature searches, bibliographies of primary studies and narrative reviews, and manual searches of personal archives. Included studies presented at least one empirical association between TV viewing, video/computer game use and body fatness or physical activity among samples of children and youth aged 3-18 y. The mean sample-weighted corrected effect size (Pearson r). Based on data from 52 independent samples, the mean sample-weighted effect size between TV viewing and body fatness was 0.066 (95% CI=0.056-0.078; total N=44,707). The sample-weighted fully corrected effect size was 0.084. Based on data from six independent samples, the mean sample-weighted effect size between video/computer game use and body fatness was 0.070 (95% CI=-0.048 to 0.188; total N=1,722). The sample-weighted fully corrected effect size was 0.128. Based on data from 39 independent samples, the mean sample-weighted effect size between TV viewing and physical activity was -0.096 (95% CI=-0.080 to -0.112; total N=141,505). The sample-weighted fully corrected effect size was -0.129. Based on data from 10 independent samples, the mean sample-weighted effect size between video/computer game use and physical activity was -0.104 (95% CI=-0.080 to -0.128; total N=119,942). The sample-weighted fully corrected effect size was -0.141. A statistically significant relationship exists between TV viewing and body fatness among children and youth although it is likely to be too small to be of substantial clinical relevance. The relationship between TV viewing and physical activity is small but negative. The strength of these relationships remains virtually unchanged even after correcting for common sources of bias known to impact study outcomes. While the total amount of time per day engaged in sedentary behavior is inevitably prohibitive of physical activity, media-based inactivity may be unfairly implicated in recent epidemiologic trends of overweight and obesity among children and youth. Relationships between sedentary behavior and health are unlikely to be explained using single markers of inactivity, such as TV viewing or video/computer game use.

  4. Quantifying structural physical habitat attributes using LIDAR and hyperspectral imagery - PRK

    EPA Science Inventory

    Structural physical habitat attributes include indices of stream size, channel gradient, substrate size, habitat complexity, and riparian vegetation cover and structure. The Environmental Monitoring and Assessment Program (EMAP) is designed to assess the status and trends of ecol...

  5. Quantifying Structural Physical Habitat Attributes Using Lidar and Hyperspectral Imagery (1)

    EPA Science Inventory

    Structural physical habitat attributes include indices of stream size, channel gradient, substrate size, habitat complexity, and riparian vegetation cover and structure. The Environmental Monitoring and Assessment Program (EMAP) is designed to assess the status and trends of eco...

  6. Size of Undergraduate Physics and Astronomy Programs: Data from the AIP Enrollments and Degrees and Academic Workforce Surveys. Focus On

    ERIC Educational Resources Information Center

    Mulvey, Patrick; Tyler, John; Nicholson, Starr; Ivie, Rachel

    2017-01-01

    This report provides data on the size of degree-granting physics and astronomy departments by examining the number of bachelor's degrees awarded and the number of full-time equivalent (FTE) faculty members employed. The benchmarking data in this report is intended to allow physics and astronomy departments to see how they fit in the national…

  7. Growth in bone and body size among Asian and white girls in the Female Adolescent Maturation (FAM) study.

    PubMed

    Novotny, Rachel; Davis, James

    2015-01-01

    This study intends to identify differences in growth of Asian and White girls. Asian girls gained bone at similar rates to White girls. Physical activity was important to bone growth. Ethnic differences remained after adjusting for physical activity, demographics, and diet. Physical activity can improve bone gain. The purpose of this study is to examine differences in body size and bone growth of Asian, White, and Asian-White Mixed girls. Three prospective examinations of 99 Asian, 73 White, and 63 Mixed Asian and White girls, with a mean age of 11.0 years at enrollment were performed. Calcaneal bone mass, skeletal breadths, and body fat were measured. Physical activity, diet, and birth size were reported. The analyses examined the extent that body dimensions and bone size changed over time by demographic, diet, physical activity, body, and bone size parameters. White children were the most physically active yet had lower calcaneal ultrasound values for speed of sound (SOS). Based on regression models, bone mass, and subscapular skinfold thickness were greater in Asian girls compared to White and Asian-White Mixed girls at age 10 years. Asian-White Mixed girls had greater BMI compared to Asian or White girls. Asian girls gained body size more slowly than White girls, but changes in bone parameters did not differ significantly; Asian-White Mixed girls gained abdomen, hip, and weight more slowly than White girls. Among all girls, SOS and broadband ultrasound attenuation (BUA) increased significantly by level of physical activity before 12 years, but not after. Asian girls had more upper body (subscapular) fat at age 10 years and gained height and hip and abdomen circumferences more slowly than Asian-White and White girls. Asian girls had greater bone SOS and BUA at age 10 years but gained bone at similar rates to White girls. Physical activity was especially important to bone growth before age 12 years. However, ethnic differences remained after adjusting for physical activity, demographic, and dietary factors.

  8. Estimating the Size of Onion Epidermal Cells from Diffraction Patterns

    NASA Astrophysics Data System (ADS)

    Groff, Jeffrey R.

    2012-10-01

    Bioscience and premedical profession students are a major demographic served by introductory physics courses at many colleges and universities. Exposing these students to biological applications of physical principles will help them to appreciate physics as a useful tool for their future professions. Here I describe an experiment suitable for introductory physics where principles of wave optics are applied to probe the size of onion epidermal cells. The epidermis tissue is composed of cells of relatively uniform size and shape (Fig. 1) so the tissue acts like a one-dimensional transmission diffraction grating. The diffraction patterns generated when a laser beam passes through the tissue (Fig. 2) are analyzed and an estimate of the average width of individual onion epidermal cells is calculated. The results are compared to direct measurements taken using a light microscope. The use of microscopes and plant-cell tissue slides creates opportunities for cross-discipline collaboration between physics and biology instructors.

  9. Nano-anisotropic surface coating based on drug immobilized pendant polymer to suppress macrophage adhesion response.

    PubMed

    Kaladhar, K; Renz, H; Sharma, C P

    2015-04-01

    Exploring drug molecules for material design, to harness concepts of nano-anisotropy and ligand-receptor interactions, are rather elusive. The aim of this study is to demonstrate the bottom-up design of a single-step and bio-interactive polymeric surface coating, based on drug based pendant polymer. This can be applied on to polystyrene (PS) substrates, to suppress macrophage adhesion and spreading. The drug molecule is used in this coating for two purposes. The first one is drug as a "pendant" group, to produce nano-anisotropic properties that can enable adhesion of the coatings to the substrate. The second purpose is to use the drug as a "ligand", to produce ligand-receptor interaction, between the bound ligand and receptors of albumin, to develop a self-albumin coat over the surface, by the preferential binding of albumin in biological environment, to reduce macrophage adhesion. Our in silico studies show that, diclofenac (DIC) is an ideal drug based "ligand" for albumin. This can also act as a "pendant" group with planar aryl groups. The combination of these two factors can help to harness, both nano-anisotropic properties and biological functions to the polymeric coating. Further, the drug, diclofenac (DIC) is immobilized to the polyvinyl alcohol (PVA), to develop the pendant polymer (PVA-DIC). The interaction of bound DIC with the albumin is a ligand-receptor based interaction, as per the studies by circular dichroism, differential scanning calorimetry, and SDS-PAGE. The non-polar π-π* interactions are regulating; the interactions between PVA bound DIC-DIC interactions, leading to "nano-anisotropic condensation" to form distinct "nano-anisotropic segments" inside the polymeric coating. This is evident from, the thermo-responsiveness and uniform size of nanoparticles, as well as regular roughness in the surface coating, with similar properties as that of nanoparticles. In addition, the hydrophobic DIC-polystyrene (PS) interactions, between the PVA-DIC coating and PS-substrate produce improved coating stability. Subsequently, the PVA-DIC coated substrate has the maximum capacity to suppress the macrophage (RAW 264.7 cell line) adhesion and spreading, which is partly due to wavy-surface topography of hydrophilic PVA and preferential albumin binding capacity of PVA bound DIC. Our result shows that, such surfaces suppress the macrophages, even under stimulation with lipopolysaccharide (LPS). The modified tissue culture plates can be used as an in vitro tool, to study the macrophage response under low spatial cues. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Tunable particles alter macrophage uptake based on combinatorial effects of physical properties

    PubMed Central

    Garapaty, Anusha

    2017-01-01

    Abstract The ability to tune phagocytosis of particle‐based therapeutics by macrophages can enhance their delivery to macrophages or reduce their phagocytic susceptibility for delivery to non‐phagocytic cells. Since phagocytosis is affected by the physical and chemical properties of particles, it is crucial to identify any interplay between physical properties of particles in altering phagocytic interactions. The combinatorial effect of physical properties size, shape and stiffness was investigated on Fc receptor mediated macrophage interactions by fabrication of layer‐by‐layer tunable particles of constant surface chemistry. Our results highlight how changing particle stiffness affects phagocytic interaction intricately when combined with varying size or shape. Increase in size plays a dominant role over reduction in stiffness in reducing internalization by macrophages for spherical particles. Internalization of rod‐shaped, but not spherical particles, was highly dependent on stiffness. These particles demonstrate the interplay between size, shape and stiffness in interactions of Fc‐functionalized particles with macrophages during phagocytosis. PMID:29313025

  11. Size Constancy in Infants: 4-Month-Olds' Responses to Physical versus Retinal Image Size

    ERIC Educational Resources Information Center

    Granrud, Carl E.

    2006-01-01

    This study tested whether 4-month-old infants respond primarily to objects' physical or retinal image sizes. In the study's main experiment, infants were habituated to either a 6-cm-diameter disk at a distance of 18 cm or a 10-cm disk at 50 cm. They were then given 2 test trials in which the 6- and 10-cm disks were presented side by side at a…

  12. Theoretical analysis of the influence of aerosol size distribution and physical activity on particle deposition pattern in human lungs.

    PubMed

    Voutilainen, Arto; Kaipio, Jari P; Pekkanen, Juha; Timonen, Kirsi L; Ruuskanen, Juhani

    2004-01-01

    A theoretical comparison of modeled particle depositions in the human respiratory tract was performed by taking into account different particle number and mass size distributions and physical activity in an urban environment. Urban-air data on particulate concentrations in the size range 10 nm-10 microm were used to estimate the hourly average particle number and mass size distribution functions. The functions were then combined with the deposition probability functions obtained from a computerized ICRP 66 deposition model of the International Commission on Radiological Protection to calculate the numbers and masses of particles deposited in five regions of the respiratory tract of a male adult. The man's physical activity and minute ventilation during the day were taken into account in the calculations. Two different mass and number size distributions of aerosol particles with equal (computed) <10 microm particle mass concentrations gave clearly different deposition patterns in the central and peripheral regions of the human respiratory tract. The deposited particle numbers and masses were much higher during the day (0700-1900) than during the night (1900-0700) because an increase in physical activity and ventilation were temporally associated with highly increased traffic-derived particles in urban outdoor air. In future analyses of the short-term associations between particulate air pollution and health, it would not only be important to take into account the outdoor-to-indoor penetration of different particle sizes and human time-activity patterns, but also actual lung deposition patterns and physical activity in significant microenvironments.

  13. Comparing Child Outcomes of Physical Punishment and Alternative Disciplinary Tactics: A Meta-Analysis

    ERIC Educational Resources Information Center

    Larzelere, Robert E.; Kuhn, Brett R.

    2005-01-01

    This meta-analysis investigates differences between the effect sizes of physical punishment and alternative disciplinary tactics for child outcomes in 26 qualifying studies. Analyzing differences in effect sizes reduces systematic biases and emphasizes direct comparisons between the disciplinary tactics that parents have to select among. The…

  14. Advancing the understanding of plasma transport in mid-size stellarators

    NASA Astrophysics Data System (ADS)

    Hidalgo, Carlos; Talmadge, Joseph; Ramisch, Mirko; TJ-II, the; HXS; TJ-K Teams

    2017-01-01

    The tokamak and the stellarator are the two main candidate concepts for magnetically confining fusion plasmas. The flexibility of the mid-size stellarator devices together with their unique diagnostic capabilities make them ideally suited to study the relation between magnetic topology, electric fields and transport. This paper addresses advances in the understanding of plasma transport in mid-size stellarators with an emphasis on the physics of flows, transport control, impurity and particle transport and fast particles. The results described here emphasize an improved physics understanding of phenomena in stellarators that complements the empirical approach. Experiments in mid-size stellarators support the development of advanced plasma scenarios in Wendelstein 7-X (W7-X) and, in concert with better physics understanding in tokamaks, may ultimately lead to an advance in the prediction of burning plasma behaviour.

  15. Physical capital and the embodied nature of income inequality: gender differences in the effect of body size on workers' incomes in Canada.

    PubMed

    Perks, Thomas

    2012-02-01

    This study assesses the effects of body size--measured using the body mass index--on the income attainment of female and male workers in Canada. Using data from a national representative sample of Canadians, multivariate analyses show that, for female workers, the body size-income relationship is negative. However, for male workers, the body size-income relationship is positive and nonlinear. Using Bourdieu's conceptualization of physical capital, and Shilling's extension of it, it is argued that these results are suggestive of the relative importance of body size to the production and continuation of gender income inequality in Canada.

  16. The effects of a physical activity intervention on employees in small and medium enterprises: a mixed methods study.

    PubMed

    Edmunds, Sarah; Stephenson, Duncan; Clow, Angela

    2013-01-01

    Workplaces have potential as a setting for physical activity promotion but evidence of the effectiveness of intervention programmes in small and medium sized enterprises is limited. This paper reports the impact of an intervention which trained existing employees to promote physical activity to their colleagues. Eighty-nine previously low-active employees from 17 small and medium sized organisations participated. A mixed methods evaluation design was used. Quantitative data were collected at baseline and 6 months later using an online questionnaire. Qualitative data from a series of 6 focus groups were analysed. Repeated measures t-tests showed significant increases over time in physical activity, general health rating, satisfaction with life and positive mood states. There were significant decreases in body mass index (BMI), perceived stress, negative mood states and presenteeism. There was no change in absenteeism. Analysis of focus group data provided further insight into the impact of the intervention. Five major themes emerged: awareness of physical activity; sustaining physical activity behaviour change; improved health and well-being; enhanced social networks; and embedding physical activity in the workplace culture. This study shows it is feasible and effective to train employees in small and medium sized enterprises to support their colleagues in physical activity behaviour change.

  17. Secondary Services in Physics.

    ERIC Educational Resources Information Center

    Cooper, Marianne; Terry, Edward

    The basic characteristics of sixty-nine secondary services in physics were analyzed in terms of sponsorship and distribution by: (1) country of origin, (2) language, (3) age, (4) frequency of publication, (5) subject and geographical coverage and (6) size. The eight major services, in terms of size, are identified. The use of the services by the…

  18. Properties of bio-based medium density fiberboard

    Treesearch

    Sangyeob Lee; Todd F. Shupe; Chung Y. Hse

    2006-01-01

    In order to utilize agricultural waste fibers as an alternative resource for composites, a number of variables were investigated to determine whether the mechanical and physical properties of agro-based fiberboard could be improved. Fibers were classified into four different mesh sizes and used to evaluated the effect of fiber size on the mechanical and physical...

  19. Sizing up the Threat: The Envisioned Physical Formidability of Terrorists Tracks Their Leaders' Failures and Successes

    ERIC Educational Resources Information Center

    Holbrook, Colin; Fessler, Daniel M. T.

    2013-01-01

    Victory in modern intergroup conflict derives from complex factors, including weaponry, economic resources, tactical outcomes, and leadership. We hypothesize that the mind summarizes such factors into simple metaphorical representations of physical size and strength, concrete dimensions that have determined the outcome of combat throughout both…

  20. Match-derived relative pitch area changes the physical and team tactical performance of elite soccer players in small-sided soccer games.

    PubMed

    Olthof, Sigrid B H; Frencken, Wouter G P; Lemmink, Koen A P M

    2018-07-01

    Small-sided games (SSGs) are used in training sessions to prepare for full-sized matches. For the same number of players, smaller pitch sizes result in decreased physical performance and shorter interpersonal distances. A relative pitch area derived from the full-sized match results in larger pitch sizes and this may increase the fit between SSGs and full-sized matches. This study aimed to investigate SSGs with a traditional small pitch and a match-derived relative pitch area in youth elite soccer players. Four age categories (under-13, under-15, under-17 and under-19) played 4 vs. 4 plus goalkeepers on a small (40x30m, 120m 2 relative pitch area) and large pitch (68x47m, 320m 2 relative pitch area). The number of games per age category ranged 15-30. Positional data (LPM-system) were collected to determine physical (total distance covered, high intensity distance and number of sprints) and team tactical (inter-team distance, LPW-ratio, surface area, stretch indices, goalkeeper-defender distance) performance measures and tactical variability. On a large pitch, physical performance significantly increased, inter-team and intra-team distances were significantly larger and tactical variability of intra-team distance measures significantly increased. The match-derived relative pitch area is an important training manipulation and leads to changes in physical and tactical performance 4 vs. 4 plus goalkeepers.

  1. Breaking a habit: a further role of the phonological loop in action control.

    PubMed

    Saeki, Erina; Baddeley, Alan D; Hitch, Graham J; Saito, Satoru

    2013-10-01

    Recent research has suggested that keeping track of a task goal in rapid task switching may depend on the phonological loop component of working memory. In this study, we investigated whether the phonological loop plays a similar role when a single switch extending over several trials is required after many trials on which one has performed a competing task. Participants were shown pairs of digits varying in numerical and physical size, and they were required to decide which digit was numerically or physically larger. An experimental cycle consisted of four blocks of 24 trials. In Experiment 1, participants in the task change groups performed the numerical-size judgment task during the first three blocks, and then changed to the physical-size judgment task in the fourth. Participants in the continuation groups performed only the physical-size judgment task throughout all four blocks. We found negative effects of articulatory suppression on the fourth block, but only in the task change groups. Experiment 2 was a replication, with the modification that both groups received identical instructions and practice. Experiment 3 was a further replication using numerical-size judgment as the target task. The results showed a pattern similar to that from Experiment 1, with negative effects of articulatory suppression found only in the task change group. The congruity of numerical and physical size had a reliable effect on performance in all three experiments, but unlike the task change, it did not reliably interact with articulatory suppression. The results suggest that in addition to its well-established role in rapid task switching, the phonological loop also contributes to active goal maintenance in longer-term action control.

  2. Rambrain - a library for virtually extending physical memory

    NASA Astrophysics Data System (ADS)

    Imgrund, Maximilian; Arth, Alexander

    2017-08-01

    We introduce Rambrain, a user space library that manages memory consumption of your code. Using Rambrain you can overcommit memory over the size of physical memory present in the system. Rambrain takes care of temporarily swapping out data to disk and can handle multiples of the physical memory size present. Rambrain is thread-safe, OpenMP and MPI compatible and supports Asynchronous IO. The library was designed to require minimal changes to existing programs and to be easy to use.

  3. Determinants and consequences of female attractiveness and sexiness: realistic tests with restaurant waitresses.

    PubMed

    Lynn, Michael

    2009-10-01

    Waitresses completed an on-line survey about their physical characteristics, self-perceived attractiveness and sexiness, and average tips. The waitresses' self-rated physical attractiveness increased with their breast sizes and decreased with their ages, waist-to-hip ratios, and body sizes. Similar effects were observed on self-rated sexiness, with the exception of age, which varied with self-rated sexiness in a negative, quadratic relationship rather than a linear one. Moreover, the waitresses' tips varied with age in a negative, quadratic relationship, increased with breast size, increased with having blond hair, and decreased with body size. These findings, which are discussed from an evolutionary perspective, make several contributions to the literature on female physical attractiveness. First, they replicate some previous findings regarding the determinants of female physical attractiveness using a larger, more diverse, and more ecologically valid set of stimuli than has been studied before. Second, they provide needed evidence that some of those determinants of female beauty affect interpersonal behaviors as well as attractiveness ratings. Finally, they indicate that some determinants of female physical attractiveness do not have the same effects on overt interpersonal behavior (such as tipping) that they have on attractiveness ratings. This latter contribution highlights the need for more ecologically valid tests of evolutionary theories about the determinants and consequences of female beauty.

  4. Finding the "Right-Size" Physical Therapy Workforce: International Perspective Across 4 Countries.

    PubMed

    Jesus, Tiago S; Koh, Gerald; Landry, Michel; Ong, Peck-Hoon; Lopes, António M F; Green, Peter L; Hoenig, Helen

    2016-10-01

    Finding the "right-size" physical therapy workforce is an increasingly important issue, but it has had limited study, particularly across nations. This perspective article provides a comprehensive examination of physical therapy workforce issues across 4 countries (United States, Singapore, Portugal, and Bangladesh), which were deliberately selected to allow consideration of key contextual factors. This investigation provides a theoretical model uniquely adapted to focus on variables most likely to affect physical therapy workforce needs. This theoretical model was used to guide acquisition of public domain data across the respective countries. The data then were used to provide a contextualized interpretation about the physical therapy workforce supply (ie, physical therapists per capita) across the 4 countries in light of the following factors: indicators of physical therapy need, financial and administrative barriers affecting physical therapy access and demand, the proportion of physical therapy graduates (with varying trends over time across the countries), and the role of emigration/immigration in supply inequalities among countries of lower and higher income. In addition, both the physical therapy workforce supply and scope of practice were analyzed in the context of other related professions across the 4 countries. This international comparison indicated that there may not be a "one-size-fits-all" recommendation for physical therapy workforce supply across countries or an ideal formula for its determination. The optimal, country-specific physical therapy workforce supply appears to be affected by discipline-specific health care and contextual factors that may vary across countries, and even within the same country. This article provides a conceptual framework and basis for such contextualized evaluations of the physical therapy workforce. © 2016 American Physical Therapy Association.

  5. On physical scales of dark matter halos

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zemp, Marcel, E-mail: mzemp@pku.edu.cn

    2014-09-10

    It is common practice to describe formal size and mass scales of dark matter halos as spherical overdensities with respect to an evolving density threshold. Here, we critically investigate the evolutionary effects of several such commonly used definitions and compare them to the halo evolution within fixed physical scales as well as to the evolution of other intrinsic physical properties of dark matter halos. It is shown that, in general, the traditional way of characterizing sizes and masses of halos dramatically overpredicts the degree of evolution in the last 10 Gyr, especially for low-mass halos. This pseudo-evolution leads to themore » illusion of growth even though there are no major changes within fixed physical scales. Such formal size definitions also serve as proxies for the virialized region of a halo in the literature. In general, those spherical overdensity scales do not coincide with the virialized region. A physically more precise nomenclature would be to simply characterize them by their very definition instead of calling such formal size and mass definitions 'virial'. In general, we find a discrepancy between the evolution of the underlying physical structure of dark matter halos seen in cosmological structure formation simulations and pseudo-evolving formal virial quantities. We question the importance of the role of formal virial quantities currently ubiquitously used in descriptions, models, and relations that involve properties of dark matter structures. Concepts and relations based on pseudo-evolving formal virial quantities do not properly reflect the actual evolution of dark matter halos and lead to an inaccurate picture of the physical evolution of our universe.« less

  6. Spanking and child outcomes: Old controversies and new meta-analyses.

    PubMed

    Gershoff, Elizabeth T; Grogan-Kaylor, Andrew

    2016-06-01

    Whether spanking is helpful or harmful to children continues to be the source of considerable debate among both researchers and the public. This article addresses 2 persistent issues, namely whether effect sizes for spanking are distinct from those for physical abuse, and whether effect sizes for spanking are robust to study design differences. Meta-analyses focused specifically on spanking were conducted on a total of 111 unique effect sizes representing 160,927 children. Thirteen of 17 mean effect sizes were significantly different from zero and all indicated a link between spanking and increased risk for detrimental child outcomes. Effect sizes did not substantially differ between spanking and physical abuse or by study design characteristics. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  7. Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk.

    PubMed

    Simons, C C J M; Schouten, L J; Godschalk, R; van Engeland, M; van den Brandt, P A; van Schooten, F J; Weijenberg, M P

    2015-09-01

    Insulin-like growth factors (IGFs) have been associated with growth, body size, physical activity and colorectal cancer (CRC). We hypothesized that variants in IGF-related genes increase the CRC susceptibility associated with a larger body size and a lack of physical activity. We assessed this in The Netherlands Cohort Study. Participants (n = 120852) completed a baseline questionnaire on diet and cancer. ~75% returned toenail clippings. Using a case-cohort approach and 16.3 years of follow-up, toenail DNA from 3768 subcohort members and 2580 CRC cases was genotyped. We aggregated unfavorable alleles (potentially increasing CRC risk) for 18 single nucleotide polymorphisms in 8 genes into a sum score. The sum score (in tertiles) and an IGF1 19-CA repeat polymorphism (19/19, 19/non-19 and non-19/non-19 repeats) in combination with body size (mostly in tertiles) and (non-)occupational physical activity (>12, 8-12 and <8 kJ/min in the job and >90, >60-90, >30-60 and ≤30 min/day) were analyzed by Cox regression. Increasingly higher hazard ratios (HRs) for CRC were observed for a larger adult body mass index, larger trouser size and tallness in the presence of more unfavorable alleles in men. HRs (95% confidence intervals) for joint effects were 1.55 (1.06-2.25), 1.78 (1.29-2.46) and 1.48 (1.01-2.17), respectively. In women, variant repeat alleles halved CRC risk irrespective of body size and physical activity. Almost no interactions tested significant. To conclude, a larger body size was a CRC risk factor in men in the presence of an accumulation of unfavorable alleles in IGF-related genes, but interactions were generally nonsignificant. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  8. Body Size, Physical Activity and Risk of Colorectal Cancer with or without the CpG Island Methylator Phenotype (CIMP)

    PubMed Central

    Hughes, Laura A. E.; Simons, Colinda C. J. M.; van den Brandt, Piet A.; Goldbohm, R. Alexandra; de Goeij, Anton F.; de Bruïne, Adriaan P.; van Engeland, Manon; Weijenberg, Matty P.

    2011-01-01

    Background We investigated how body size and physical activity influence the risk of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Methods In the Netherlands Cohort Study (n = 120,852), risk factors were self-reported at baseline in 1986. After 7.3 years of follow-up, 603 cases and 4,631 sub-cohort members were available. CIMP status according to the Weisenberger markers was determined using methylation specific PCR on DNA from paraffin embedded tumor tissue. Hazard rate ratios (HR) and 95% confidence intervals for CIMP (27.7%) and non-CIMP (72.3%) tumors were calculated according to BMI, BMI at age 20, BMI change, trouser/skirt size, height, and physical activity. Results BMI modeled per 5 kg/m2 increase was associated with both CIMP and non-CIMP tumors, however, HRs were attenuated when additionally adjusted for trouser/skirt size. Trouser/skirt size, per 2 size increase, was associated with both tumor subtypes, even after adjustment for BMI (CIMP HR: 1.20, 95%CI: 1.01–1.43; non-CIMP HR: 1.14, 95%CI: 1.04–1.28). Height per 5 cm was associated with both tumor sub-types, but HRs were attenuated when adjusted for body weight. BMI at age 20 was positively associated with increased risk of CIMP tumors and the association was significantly less pronounced for non-CIMP tumors (P-heterogeneity = 0.01). Physical activity was inversely associated with both subtypes, but a dose-response association was observed only for non-CIMP tumors (P-trend = 0.02). Conclusions Body size, especially central adiposity, may increase the risk of both CIMP and non-CIMP tumors. Body fat at young age may differentially influence risk. Physical activity appears to decrease the risk of CRC regardless of these molecular subtypes. PMID:21483668

  9. Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP).

    PubMed

    Hughes, Laura A E; Simons, Colinda C J M; van den Brandt, Piet A; Goldbohm, R Alexandra; de Goeij, Anton F; de Bruïne, Adriaan P; van Engeland, Manon; Weijenberg, Matty P

    2011-04-05

    We investigated how body size and physical activity influence the risk of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). In the Netherlands Cohort Study (n = 120,852), risk factors were self-reported at baseline in 1986. After 7.3 years of follow-up, 603 cases and 4,631 sub-cohort members were available. CIMP status according to the Weisenberger markers was determined using methylation specific PCR on DNA from paraffin embedded tumor tissue. Hazard rate ratios (HR) and 95% confidence intervals for CIMP (27.7%) and non-CIMP (72.3%) tumors were calculated according to BMI, BMI at age 20, BMI change, trouser/skirt size, height, and physical activity. BMI modeled per 5 kg/m(2) increase was associated with both CIMP and non-CIMP tumors, however, HRs were attenuated when additionally adjusted for trouser/skirt size. Trouser/skirt size, per 2 size increase, was associated with both tumor subtypes, even after adjustment for BMI (CIMP HR: 1.20, 95%CI: 1.01-1.43; non-CIMP HR: 1.14, 95%CI: 1.04-1.28). Height per 5 cm was associated with both tumor sub-types, but HRs were attenuated when adjusted for body weight. BMI at age 20 was positively associated with increased risk of CIMP tumors and the association was significantly less pronounced for non-CIMP tumors (P-heterogeneity = 0.01). Physical activity was inversely associated with both subtypes, but a dose-response association was observed only for non-CIMP tumors (P-trend = 0.02). Body size, especially central adiposity, may increase the risk of both CIMP and non-CIMP tumors. Body fat at young age may differentially influence risk. Physical activity appears to decrease the risk of CRC regardless of these molecular subtypes.

  10. Family size, the physical environment, and socioeconomic effects across the stature distribution.

    PubMed

    Carson, Scott Alan

    2012-04-01

    A neglected area in historical stature studies is the relationship between stature and family size. Using robust statistics and a large 19th century data set, this study documents a positive relationship between stature and family size across the stature distribution. The relationship between material inequality and health is the subject of considerable debate, and there was a positive relationship between stature and wealth and an inverse relationship between stature and material inequality. After controlling for family size and wealth variables, the paper reports a positive relationship between the physical environment and stature. Copyright © 2012 Elsevier GmbH. All rights reserved.

  11. Size Distributions of Solar Proton Events: Methodological and Physical Restrictions

    NASA Astrophysics Data System (ADS)

    Miroshnichenko, L. I.; Yanke, V. G.

    2016-12-01

    Based on the new catalogue of solar proton events (SPEs) for the period of 1997 - 2009 (Solar Cycle 23) we revisit the long-studied problem of the event-size distributions in the context of those constructed for other solar-flare parameters. Recent results on the problem of size distributions of solar flares and proton events are briefly reviewed. Even a cursory acquaintance with this research field reveals a rather mixed and controversial picture. We concentrate on three main issues: i) SPE size distribution for {>} 10 MeV protons in Solar Cycle 23; ii) size distribution of {>} 1 GV proton events in 1942 - 2014; iii) variations of annual numbers for {>} 10 MeV proton events on long time scales (1955 - 2015). Different results are critically compared; most of the studies in this field are shown to suffer from vastly different input datasets as well as from insufficient knowledge of underlying physical processes in the SPEs under consideration. New studies in this field should be made on more distinct physical and methodological bases. It is important to note the evident similarity in size distributions of solar flares and superflares in Sun-like stars.

  12. Body size ideals and dissatisfaction in Ghanaian adolescents: role of media, lifestyle and well-being.

    PubMed

    Michels, N; Amenyah, S D

    2017-05-01

    To inspire effective health promotion campaigns, we tested the relationship of ideal body size and body size dissatisfaction with (1) the potential resulting health-influencing factors diet, physical activity and well-being; and (2) with media as a potential influencer of body ideals. This is a cross-sectional study in 370 Ghanaian adolescents (aged 11-18 years). Questionnaires included disordered eating (EAT26), diet quality (FFQ), physical activity (IPAQ), well-being (KINDL) and media influence on appearance (SATAQ: pressure, internalisation and information). Ideal body size and body size dissatisfaction were assessed using the Stunkard figure rating scale. Body mass index (BMI), skinfolds and waist were measured. Linear regressions were adjusted for gender, age and parental education. Also, mediation was tested: 'can perceived media influence play a role in the effects of actual body size on body size dissatisfaction?'. Body size dissatisfaction was associated with lower well-being and more media influence (pressure and internalisation) but not with physical activity, diet quality or disordered eating. An underweight body size ideal might worsen disordered eating but was not significantly related to the other predictors of interest. Only a partial mediation effect by media pressure was found: especially overweight adolescents felt media pressure, and this media pressure was associated with more body size dissatisfaction. To prevent disordered eating and low well-being, health messages should include strategies that reduce body size dissatisfaction and increase body esteem by not focussing on the thin body ideal. Changing body size ideals in the media might be an appropriate way since media pressure was a mediator in the BMI-dissatisfaction relation. Copyright © 2017 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  13. A blind human expert echolocator shows size constancy for objects perceived by echoes.

    PubMed

    Milne, Jennifer L; Anello, Mimma; Goodale, Melvyn A; Thaler, Lore

    2015-01-01

    Some blind humans make clicking noises with their mouth and use the reflected echoes to perceive objects and surfaces. This technique can operate as a crude substitute for vision, allowing human echolocators to perceive silent, distal objects. Here, we tested if echolocation would, like vision, show size constancy. To investigate this, we asked a blind expert echolocator (EE) to echolocate objects of different physical sizes presented at different distances. The EE consistently identified the true physical size of the objects independent of distance. In contrast, blind and blindfolded sighted controls did not show size constancy, even when encouraged to use mouth clicks, claps, or other signals. These findings suggest that size constancy is not a purely visual phenomenon, but that it can operate via an auditory-based substitute for vision, such as human echolocation.

  14. Meta-analysis of workplace physical activity interventions.

    PubMed

    Conn, Vicki S; Hafdahl, Adam R; Cooper, Pamela S; Brown, Lori M; Lusk, Sally L

    2009-10-01

    Most adults do not achieve adequate physical activity levels. Despite the potential benefits of worksite health promotion, no previous comprehensive meta-analysis has summarized health and physical activity behavior outcomes from such programs. This comprehensive meta-analysis integrated the extant wide range of worksite physical activity intervention research. Extensive searching located published and unpublished intervention studies reported from 1969 through 2007. Results were coded from primary studies. Random-effects meta-analytic procedures, including moderator analyses, were completed in 2008. Effects on most variables were substantially heterogeneous because diverse studies were included. Standardized mean difference (d) effect sizes were synthesized across approximately 38,231 subjects. Significantly positive effects were observed for physical activity behavior (0.21); fitness (0.57); lipids (0.13); anthropometric measures (0.08); work attendance (0.19); and job stress (0.33). The significant effect size for diabetes risk (0.98) is less robust given small sample sizes. The mean effect size for fitness corresponds to a difference between treatment minus control subjects' means on VO2max of 3.5 mL/kg/min; for lipids, -0.2 on the ratio of total cholesterol to high-density lipoprotein; and for diabetes risk, -12.6 mg/dL on fasting glucose. These findings document that some workplace physical activity interventions can improve both health and important worksite outcomes. Effects were variable for most outcomes, reflecting the diversity of primary studies. Future primary research should compare interventions to confirm causal relationships and further explore heterogeneity.

  15. Association of School Environment and After-School Physical Activity with Health-Related Physical Fitness among Junior High School Students in Taiwan

    PubMed Central

    Lo, Kai-Yang; Wu, Min-Chen; Tung, Shu-Chin; Hsieh, City C.; Yao, Hsueh-Hua; Ho, Chien-Chang

    2017-01-01

    The relationship between students’ school environment and exercise habits is complex, and is affected by numerous factors. However, the few studies that have been conducted on this relationship have reported inconsistent results, especially regarding Taiwanese students. We conducted this cross-sectional study to investigate the association of school environment and after-school physical activity with health-related physical fitness in Taiwanese adolescents. Data were drawn from a national survey conducted by the Ministry of Education in Taiwan in 2008 of health-related physical fitness measurements among junior high school students (649,442 total) in grades seven to nine. School environment (level of urbanization, school size, presence of sports field or gymnasium) and after-school physical activity were assessed for their association with adolescents’ physical fitness measurements (body mass index (BMI), bent-leg sit-ups, 800-/1600-m run, sit-and-reach, standing long jump). Urban boys and girls perform significantly better in muscle strength and endurance, cardiorespiratory endurance, flexibility, and explosive power; girls from rural areas exhibited significantly worse scores in body composition. Boys from large-size schools performed the worst in cardiorespiratory endurance, flexibility, and explosive power; whereas girls from large-size schools performed the worst in muscle strength, muscle endurance, and explosive power, but had the best score for body composition. However, the differences in body composition of boys from large-, medium-, and small- size schools did not reach a statistically significant level. Adolescents of both genders in schools with a sports field or gymnasium exhibited significantly better in muscle strength and endurance, cardiorespiratory endurance, and explosive power. Boys in schools with a sports field or gymnasium had significantly better body composition; girls in schools with sports field or gymnasium differed significantly in flexibility. Adolescents of both genders who participated in physical activity after school had significantly better body composition, cardiorespiratory endurance, and flexibility. Boys who participated in physical activity after school significantly differed in explosive power, whereas girls who participated in physical activity after school exhibited significantly better flexibility. Thus, the current study demonstrated that some factors, including urbanization (school location in rural or urban areas), school size, school facility provision (school with or without sports fields or gymnasiums), and after-school physical activity participation are more important than others in shaping adolescents’ physical fitness in Taiwan; meanwhile, these association patterns differed by gender. PMID:28098836

  16. Association of School Environment and After-School Physical Activity with Health-Related Physical Fitness among Junior High School Students in Taiwan.

    PubMed

    Lo, Kai-Yang; Wu, Min-Chen; Tung, Shu-Chin; Hsieh, City C; Yao, Hsueh-Hua; Ho, Chien-Chang

    2017-01-15

    The relationship between students' school environment and exercise habits is complex, and is affected by numerous factors. However, the few studies that have been conducted on this relationship have reported inconsistent results, especially regarding Taiwanese students. We conducted this cross-sectional study to investigate the association of school environment and after-school physical activity with health-related physical fitness in Taiwanese adolescents. Data were drawn from a national survey conducted by the Ministry of Education in Taiwan in 2008 of health-related physical fitness measurements among junior high school students (649,442 total) in grades seven to nine.School environment (level of urbanization, school size, presence of sports field or gymnasium) and after-school physical activity were assessed for their association with adolescents' physical fitness measurements (body mass index (BMI), bent-leg sit-ups, 800-/1600-m run, sit-and-reach, standing long jump). Urban boys and girls perform significantly better in muscle strength and endurance, cardiorespiratory endurance, flexibility, and explosive power; girls from rural areas exhibited significantly worse scores in body composition. Boys from large-size schools performed the worst in cardiorespiratory endurance, flexibility, and explosive power; whereas girls from large-size schools performed the worst in muscle strength, muscle endurance, and explosive power, but had the best score for body composition. However, the differences in body composition of boys from large-, medium-, and small- size schools did not reach a statistically significant level. Adolescents of both genders in schools with a sports field or gymnasium exhibited significantly better in muscle strength and endurance, cardiorespiratory endurance, and explosive power. Boys in schools with a sports field or gymnasium had significantly better body composition; girls in schools with sports field or gymnasium differed significantly in flexibility. Adolescents of both genders who participated in physical activity after school had significantly better body composition, cardiorespiratory endurance, and flexibility. Boys who participated in physical activity after school significantly differed in explosive power, whereas girls who participated in physical activity after school exhibited significantly better flexibility. Thus, the current study demonstrated that some factors, including urbanization (school location in rural or urban areas), school size, school facility provision (school with or without sports fields or gymnasiums), and after-school physical activity participation are more important than others in shaping adolescents' physical fitness in Taiwan; meanwhile, these association patterns differed by gender.

  17. Socioeconomic Factors Influence Physical Activity and Sport in Quebec Schools.

    PubMed

    Morin, Pascale; Lebel, Alexandre; Robitaille, Éric; Bisset, Sherri

    2016-11-01

    School environments providing a wide selection of physical activities and sufficient facilities are both essential and formative to ensure young people adopt active lifestyles. We describe the association between school opportunities for physical activity and socioeconomic factors measured by low-income cutoff index, school size (number of students), and neighborhood population density. A cross-sectional survey using a 2-stage stratified sampling method built a representative sample of 143 French-speaking public schools in Quebec, Canada. Self-administered questionnaires collected data describing the physical activities offered and schools' sports facilities. Descriptive and bivariate analyses were performed separately for primary and secondary schools. In primary schools, school size was positively associated with more intramural and extracurricular activities, more diverse interior facilities, and activities promoting active transportation. Low-income primary schools were more likely to offer a single gym. Low-income secondary schools offered lower diversity of intramural activities and fewer exterior sporting facilities. High-income secondary schools with a large school size provided a greater number of opportunities, larger infrastructures, and a wider selection of physical activities than smaller low-income schools. Results reveal an overall positive association between school availability of physical and sport activity and socioeconomic factors. © 2016, American School Health Association.

  18. Latino Civic Group Participation, Social Networks, and Physical Activity.

    PubMed

    Marquez, Becky; Gonzalez, Patricia; Gallo, Linda; Ji, Ming

    2016-07-01

    We examined whether social networks and resource awareness for physical activity may mediate the relationship between civic group participation and physical activity. This is a cross-sectional study of a randomly selected sample of 335 Latinos (mean age 42.1 ± 16.4 years) participating in the San Diego Prevention Research Center's 2009 Household Community Survey. Serial multiple mediation analysis tested the hypothesis that civic group participation is associated with meeting physical activity recommendations through an indirect mechanism of larger social networks followed by greater knowledge of physical activity community resources. The indirect effects of level of civic group participation as well as religious, health, neighborhood, or arts group participation on meeting national physical activity recommendations were significant in models testing pathways through social network size and physical activity resource awareness. The direct effect was only significant for health group indicating that participating in a health group predicted physical activity independent of social network size and awareness of physical activity resources. Belonging to civic groups may promote physical activity engagement through social network diffusion of information on community physical activity resources which has implications for health.

  19. The Effect of Rheological Properties of Foods on Bolus Characteristics After Mastication

    PubMed Central

    Hwang, Junah; Bae, Jung Hyun; Kang, Si Hyun; Seo, Kyung Mook; Kim, Byong Ki; Lee, Sook Young

    2012-01-01

    Objective To evaluate the effects of physical properties of foods on the changes of viscosity and mass as well as the particle size distribution after mastication. Method Twenty subjects with no masticatory disorders were recruited. Six grams of four solid foods of different textures (banana, tofu, cooked-rice, cookie) were provided, and the viscosity and mass after 10, 20, and 30 cycles of mastication and just before swallowing were measured. The physical properties of foods, such as hardness, cohesiveness, and adhesiveness, were measured with a texture analyzer. Wet sieving and laser diffraction were used to determine the distribution of food particle size. Results When we measured the physical characteristics of foods, the cookie was the hardest food, and the banana exhibited marked adhesiveness. Tofu and cooked-rice exhibited a highly cohesive nature. As the number of mastication cycles increased, the masses of all foods were significantly increased (p<0.05), and the viscosity was significantly decreased in the case of banana, tofu, and cooked-rice (p<0.05). The mass and viscosity of all foods were significantly different between the foods after mastication (p<0.05). Analyzing the distribution of the particle size, that of the bolus was different between foods. However, the curves representing the particle size distribution for each food were superimposable for most subjects. Conclusion The viscosity and particle size distribution of the bolus were different between solid foods that have different physical properties. Based on this result, the mastication process and food bolus formation were affected by the physical properties of the food. PMID:23342309

  20. Relationship between macrobenthos and physical habitat characters in tidal flat in eastern Seto Inland Sea, Japan.

    PubMed

    Otani, Sosuke; Kozuki, Yasunori; Kurata, Kengo; Ueda, Kaori; Nakai, Shigefumi; Murakami, Hitoshi

    2008-01-01

    The investigations were carried out at 6 tidal flats located on the eastern part of the Seto Inland Sea, Japan. This study was focused on physical characteristics of sediments, namely as particle size of sediment and difference in elevation, and generalizes the relationship between sediments and macrobenthos. A total of 192 species were collected at 187 stations at 6 tidal flats. Physical characteristics of sediment were classified into 9 groups by cluster analysis in relation to sediment particle size and difference in elevation. Those groups had also significant difference in physical characteristics of sediments, and were characterized by some specific macrobenthos species. Distribution of macrobenthos can be explained by the classification of physical characteristics of sediment. These findings show the possibility to predict the variety of macrobenthos community using the physical characteristics of sediment.

  1. Body Size at Birth, Physical Development and Cognitive Outcomes in Early Childhood: Evidence from the Longitudinal Survey of Australian Children

    ERIC Educational Resources Information Center

    Ulker, Aydogan

    2016-01-01

    Using a rich sample created from the Longitudinal Survey of Australian Children, we investigate the extent to which the relationship between body size at birth and early childhood cognitive skills is mediated by physical development indicators. Consistent with existing evidence from other countries, we find a significant relationship between body…

  2. Examining the Job-Related, Psychological, and Physical Outcomes of Workplace Sexual Harassment: A Meta-Analytic Review

    ERIC Educational Resources Information Center

    Chan, Darius K-S.; Lam, Chun Bun; Chow, Suk Yee; Cheung, Shu Fai

    2008-01-01

    This study was designed to examine the job-related, psychological, and physical outcomes of sexual harassment in the workplace. Using a meta-analytic approach, we analyzed findings from 49 primary studies, with a total sample size of 89,382, to obtain estimates of the population mean effect size of the association between sexual harassment and…

  3. High Energy Colliders

    NASA Astrophysics Data System (ADS)

    Palmer, R. B.; Gallardo, J. C.

    INTRODUCTION PHYSICS CONSIDERATIONS GENERAL REQUIRED LUMINOSITY FOR LEPTON COLLIDERS THE EFFECTIVE PHYSICS ENERGIES OF HADRON COLLIDERS HADRON-HADRON MACHINES LUMINOSITY SIZE AND COST CIRCULAR e^{+}e^- MACHINES LUMINOSITY SIZE AND COST e^{+}e^- LINEAR COLLIDERS LUMINOSITY CONVENTIONAL RF SUPERCONDUCTING RF AT HIGHER ENERGIES γ - γ COLLIDERS μ ^{+} μ^- COLLIDERS ADVANTAGES AND DISADVANTAGES DESIGN STUDIES STATUS AND REQUIRED R AND D COMPARISION OF MACHINES CONCLUSIONS DISCUSSION

  4. Physical parameters of chlorphenamine maleate suppositories and its release as a function of particle size, concentration and nature of the base.

    PubMed

    el-Din, E N; Mursi, N M; Elbary, A A; Foda, N

    1977-01-01

    Suppositories of chlorphenamine maleate were formulated. The influence of particle size and percentage concentration of chlorphenamine maleate on the physical standards of its suppositories as well as the release of the drug from oily base (cacao butter), water-soluble base (carbowax) and emulsifying base (Witepsol) has been investigated.

  5. Inequality between size and angular momentum for bodies.

    PubMed

    Dain, Sergio

    2014-01-31

    A universal inequality that bounds the angular momentum of a body by the square of its size is presented and heuristic physical arguments are given to support it. We prove a version of this inequality, as consequence of the Einstein equations, for the case of rotating axially symmetric, constant density, bodies. Finally, the physical relevance of this result is discussed.

  6. Relationships Between Body Size Satisfaction and Weight Control Practices Among US Adults

    PubMed Central

    Millstein, Rachel A.; Carlson, Susan A.; Fulton, Janet E.; Galuska, Deborah A.; Zhang, Jian; Blanck, Heidi M.; Ainsworth, Barbara E.

    2008-01-01

    Context Few studies of US adults have specifically examined body size satisfaction Objectives Describe correlates of body size satisfaction and examine whether satisfaction was associated with trying to lose weight or specific weight control practices among US adults using a national sample of women and men. Design, Setting & Participants The National Physical Activity and Weight Loss Survey (NPAWLS) was a population-based, cross-sectional telephone survey of US adults (n = 9740). Main Outcome Measures Participants reported their weight, height, body size satisfaction, and weight loss practices. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated for each dependent variable. Results Among women and men, higher body mass index (BMI) was significantly associated with body size dissatisfaction. Dissatisfaction, compared with being very satisfied, was positively associated with trying to lose weight among women and men. This association was modified by BMI for women (OR normal weight = 19.69, overweight = 8.79, obese = 4.05; P < .01 for interaction) but not men (OR normal weight = 8.72, overweight = 10.50, obese = 7.86; P = 0.93 for interaction). Compared with women who were very satisfied, dissatisfied women used diet more (OR = 2.03), but not physical activity/exercise (OR = 0.55) or both strategies (OR = 0.63), to try to lose weight. Men who were somewhat satisfied, compared with those who were very satisfied, were more likely to use physical activity/exercise (OR = 1.64) and both diet and physical activity/exercise (OR = 1.54) to try to lose weight. Conclusion These findings highlight the sex differences in body size satisfaction, actions taken to try to lose weight, and the importance of considering body size satisfaction when designing weight-management programs. PMID:18596944

  7. Aerosol physical properties from satellite horizon inversion

    NASA Technical Reports Server (NTRS)

    Gray, C. R.; Malchow, H. L.; Merritt, D. C.; Var, R. E.; Whitney, C. K.

    1973-01-01

    The feasibility is investigated of determining the physical properties of aerosols globally in the altitude region of 10 to 100 km from a satellite horizon scanning experiment. The investigation utilizes a horizon inversion technique previously developed and extended. Aerosol physical properties such as number density, size distribution, and the real and imaginary components of the index of refraction are demonstrated to be invertible in the aerosol size ranges (0.01-0.1 microns), (0.1-1.0 microns), (1.0-10 microns). Extensions of previously developed radiative transfer models and recursive inversion algorithms are displayed.

  8. Physical states and finite-size effects in Kitaev's honeycomb model: Bond disorder, spin excitations, and NMR line shape

    NASA Astrophysics Data System (ADS)

    Zschocke, Fabian; Vojta, Matthias

    2015-07-01

    Kitaev's compass model on the honeycomb lattice realizes a spin liquid whose emergent excitations are dispersive Majorana fermions and static Z2 gauge fluxes. We discuss the proper selection of physical states for finite-size simulations in the Majorana representation, based on a recent paper by F. L. Pedrocchi, S. Chesi, and D. Loss [Phys. Rev. B 84, 165414 (2011), 10.1103/PhysRevB.84.165414]. Certain physical observables acquire large finite-size effects, in particular if the ground state is not fermion-free, which we prove to generally apply to the system in the gapless phase and with periodic boundary conditions. To illustrate our findings, we compute the static and dynamic spin susceptibilities for finite-size systems. Specifically, we consider random-bond disorder (which preserves the solubility of the model), calculate the distribution of local flux gaps, and extract the NMR line shape. We also predict a transition to a random-flux state with increasing disorder.

  9. Unbiased estimates of galaxy scaling relations from photometric redshift surveys

    NASA Astrophysics Data System (ADS)

    Rossi, Graziano; Sheth, Ravi K.

    2008-06-01

    Many physical properties of galaxies correlate with one another, and these correlations are often used to constrain galaxy formation models. Such correlations include the colour-magnitude relation, the luminosity-size relation, the fundamental plane, etc. However, the transformation from observable (e.g. angular size, apparent brightness) to physical quantity (physical size, luminosity) is often distance dependent. Noise in the distance estimate will lead to biased estimates of these correlations, thus compromising the ability of photometric redshift surveys to constrain galaxy formation models. We describe two methods which can remove this bias. One is a generalization of the Vmax method, and the other is a maximum-likelihood approach. We illustrate their effectiveness by studying the size-luminosity relation in a mock catalogue, although both methods can be applied to other scaling relations as well. We show that if one simply uses photometric redshifts one obtains a biased relation; our methods correct for this bias and recover the true relation.

  10. Simulating galactic dust grain evolution on a moving mesh

    NASA Astrophysics Data System (ADS)

    McKinnon, Ryan; Vogelsberger, Mark; Torrey, Paul; Marinacci, Federico; Kannan, Rahul

    2018-05-01

    Interstellar dust is an important component of the galactic ecosystem, playing a key role in multiple galaxy formation processes. We present a novel numerical framework for the dynamics and size evolution of dust grains implemented in the moving-mesh hydrodynamics code AREPO suited for cosmological galaxy formation simulations. We employ a particle-based method for dust subject to dynamical forces including drag and gravity. The drag force is implemented using a second-order semi-implicit integrator and validated using several dust-hydrodynamical test problems. Each dust particle has a grain size distribution, describing the local abundance of grains of different sizes. The grain size distribution is discretised with a second-order piecewise linear method and evolves in time according to various dust physical processes, including accretion, sputtering, shattering, and coagulation. We present a novel scheme for stochastically forming dust during stellar evolution and new methods for sub-cycling of dust physics time-steps. Using this model, we simulate an isolated disc galaxy to study the impact of dust physical processes that shape the interstellar grain size distribution. We demonstrate, for example, how dust shattering shifts the grain size distribution to smaller sizes resulting in a significant rise of radiation extinction from optical to near-ultraviolet wavelengths. Our framework for simulating dust and gas mixtures can readily be extended to account for other dynamical processes relevant in galaxy formation, like magnetohydrodynamics, radiation pressure, and thermo-chemical processes.

  11. School Facility Recommendations for Class Size Reduction.

    ERIC Educational Resources Information Center

    Evans, Ann M.

    The California Department of Education encourages its school districts to make every effort to reduce classroom size and maintain the physical size of 960 square feet for elementary schools and 1,350 square feet for kindergartens. This report examines the Code of Regulations relative to classroom size in elementary, kindergarten, and special…

  12. Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study

    PubMed Central

    Soleimani, A.; Rasta, S.H.; Banaei, T.; Asgharsharghi Bonab, A.

    2017-01-01

    Introduction: The aim of the present study was to determine burn intensity in retinal laser photocoagulation based on laser parameters; wavelength, power, beam size and pulse duration, using Optical Coherence Tomography (OCT), fundus camera, physical eye model and computer simulation in a clinical study. Materials and Methods: Participants were 10 adult patients between 50-80 years with proliferative diabetic retinopathy. A multicolor-photo coagulator with 532 nm green and 672 nm red for retina photocoagulation in diabetic retinopathy was used to investigate the participants. Lesion size was measured for spot sizes 50 and 100 μm, with 100 and 150 mW laser power, and pulse duration 50 and 100 ms by OCT. Artificial eye and Zemax-optical design software were used with the same laser parameters. Results: Appearance of OCT and fundus images showed direct relationship between retina burn size and lesion intensity with exposure time and power and also reverse relationship with laser spot size. Compared to red wavelength, burn size and lesion intensity increased in green wavelength. On the other hand, results from physical eye model were the same as clinical examination shown. Laser spot size in retina with Zemax simulation demonstrated that red wavelength was greater than green one. Conclusion: This study showed shorter pulses provide decrease in duration of laser surgery with significantly reduced pain. Results and calculations described in this article can help clinicians adjusting the required total coagulated area, the number of lesions and pattern density. PMID:29445713

  13. Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study.

    PubMed

    Soleimani, A; Rasta, S H; Banaei, T; Asgharsharghi Bonab, A

    2017-12-01

    The aim of the present study was to determine burn intensity in retinal laser photocoagulation based on laser parameters; wavelength, power, beam size and pulse duration, using Optical Coherence Tomography (OCT), fundus camera, physical eye model and computer simulation in a clinical study. Participants were 10 adult patients between 50-80 years with proliferative diabetic retinopathy. A multicolor-photo coagulator with 532 nm green and 672 nm red for retina photocoagulation in diabetic retinopathy was used to investigate the participants. Lesion size was measured for spot sizes 50 and 100 μm, with 100 and 150 mW laser power, and pulse duration 50 and 100 ms by OCT. Artificial eye and Zemax-optical design software were used with the same laser parameters. Appearance of OCT and fundus images showed direct relationship between retina burn size and lesion intensity with exposure time and power and also reverse relationship with laser spot size. Compared to red wavelength, burn size and lesion intensity increased in green wavelength. On the other hand, results from physical eye model were the same as clinical examination shown. Laser spot size in retina with Zemax simulation demonstrated that red wavelength was greater than green one. This study showed shorter pulses provide decrease in duration of laser surgery with significantly reduced pain. Results and calculations described in this article can help clinicians adjusting the required total coagulated area, the number of lesions and pattern density.

  14. Physical therapy workforce shortage for aging and aged societies in Thailand.

    PubMed

    Kraiwong, Ratchanok; Vongsirinavarat, Mantana; Soonthorndhada, Kusol

    2014-07-01

    According to demographic changes, the size of the aging population has rapidly increased. Thailand has been facing the "aging society" since 2005 and the "aged society" has been projected to appear by the year 2025. Increased life expectancy is associated with health problems and risks, specifically chronic diseases and disability. Aging and aged societies and related specific conditions as stroke require the provision of services from health professionals. The shortage of the physical therapy workforce in Thailand has been reported. This study investigated the size of physical therapy workforce required for the approaching aging society of Thailand and estimated the number of needed physical therapists, specifically regarding stroke condition. Evidently, the issue of the physical therapy workforce to serve aging and aged societies in Thailand requires advocating and careful arranging.

  15. Promoting Physical Education: The Link to Academic Achievement

    ERIC Educational Resources Information Center

    Smith, Nicole J.; Lounsbery, Monica

    2009-01-01

    Quality physical education is recognized for its health-related benefits and should be supported as an integral component of every school's curriculum. Unfortunately, quality physical education is not easily established or maintained. Many physical education programs face challenges such as reduced staff, large class sizes, inadequate facilities…

  16. Liberation characteristic and physical separation of printed circuit board (PCB).

    PubMed

    Guo, Chao; Wang, Hui; Liang, Wei; Fu, Jiangang; Yi, Xin

    2011-01-01

    Recycling of printed circuit board (PCB) is an important subject and to which increasing attention is paid, both in treatment of waste as well as recovery of valuable material terms. Precede physical and mechanical method, a good liberation is the premise to further separation. In this study, two-step crushing process is employed, and standard sieve is applied to screen crushed material to different size fractions, moreover, the liberation situation and particles shape in different size are observed. Then metal of the PCB is separated by physical methods, including pneumatic separation, electrostatic separation and magnetic separation, and major metal contents are characterized by inductively coupled plasma emission spectrometry (ICP-AES). Results show that the metal and nonmetal particles of PCB are dissociated completely under the crush size 0.6mm; metal is mainly enriched in the four size fractions between 0.15 and 1.25 mm; relatively, pneumatic separation is suitable for 0.6-0.9 mm size fraction, while the electrostatic separation is suitable for three size fractions that are 0.15-0.3mm, 0.3-0.6mm and 0.9-1.25 mm. The whole process that involves crushing, electrostatic and magnetic separation has formed a closed cycle that can return material and provide salable product. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

  17. EXTENDING THE FLOOR AND THE CEILING FOR ASSESSMENT OF PHYSICAL FUNCTION

    PubMed Central

    Fries, James F.; Lingala, Bharathi; Siemons, Liseth; Glas, Cees A. W.; Cella, David; Hussain, Yusra N; Bruce, Bonnie; Krishnan, Eswar

    2014-01-01

    Objective The objective of the current study was to improve the assessment of physical function by improving the precision of assessment at the floor (extremely poor function) and at the ceiling (extremely good health) of the health continuum. Methods Under the NIH PROMIS program, we developed new physical function floor and ceiling items to supplement the existing item bank. Using item response theory (IRT) and the standard PROMIS methodology, we developed 30 floor items and 26 ceiling items and administered them during a 12-month prospective observational study of 737 individuals at the extremes of health status. Change over time was compared across anchor instruments and across items by means of effect sizes. Using the observed changes in scores, we back-calculated sample size requirements for the new and comparison measures. Results We studied 444 subjects with chronic illness and/or extreme age, and 293 generally fit subjects including athletes in training. IRT analyses confirmed that the new floor and ceiling items outperformed reference items (p<0.001). The estimated post-hoc sample size requirements were reduced by a factor of two to four at the floor and a factor of two at the ceiling. Conclusion Extending the range of physical function measurement can substantially improve measurement quality, can reduce sample size requirements and improve research efficiency. The paradigm shift from Disability to Physical Function includes the entire spectrum of physical function, signals improvement in the conceptual base of outcome assessment, and may be transformative as medical goals more closely approach societal goals for health. PMID:24782194

  18. Meta-Analysis of Workplace Physical Activity Interventions

    PubMed Central

    Conn, Vicki S.; Hafdahl, Adam R.; Cooper, Pamela S.; Brown, Lori M.; Lusk, Sally L.

    2009-01-01

    Context Most adults do not achieve adequate physical activity. Despite the potential benefits of worksite health promotion, no previous comprehensive meta-analysis has summarized health and physical activity behavior outcomes from these programs. This comprehensive meta-analysis integrated the extant wide range of worksite physical activity intervention research. Evidence acquisition Extensive searching located published and unpublished intervention studies reported from 1969 through 2007. Results were coded from primary studies. Random-effects meta-analytic procedures, including moderator analyses, were completed in 2008. Evidence synthesis Effects on most variables were substantially heterogeneous because diverse studies were included. Standardized mean difference (d) effect sizes were synthesized across approximately 38,231 subjects. Significantly positive effects were observed for physical activity behavior (0.21), fitness (0.57), lipids (0.13), anthropometric measures (0.08), work attendance (0.19), and job stress (0.33). The significant effect size for diabetes risk (0.98) is more tentative given small sample sizes. Significant heterogeneity documents intervention effects varied across studies. The mean effect size for fitness corresponds to a difference between treatment minus control subjects' means on V02max of 3.5 mL/kg/min; for lipids, −0.2 on total cholesterol:HDL; and for diabetes risk, −12.6 mg/dL on fasting glucose. Conclusions These findings document that some workplace physical activity interventions can improve both health and important worksite outcomes. Effects were variable for most outcomes, reflecting the diversity of primary studies. Future primary research should compare interventions to confirm causal relationships and further explore heterogeneity. PMID:19765506

  19. Metabolic 'engines' of flight drive genome size reduction in birds.

    PubMed

    Wright, Natalie A; Gregory, T Ryan; Witt, Christopher C

    2014-03-22

    The tendency for flying organisms to possess small genomes has been interpreted as evidence of natural selection acting on the physical size of the genome. Nonetheless, the flight-genome link and its mechanistic basis have yet to be well established by comparative studies within a volant clade. Is there a particular functional aspect of flight such as brisk metabolism, lift production or maneuverability that impinges on the physical genome? We measured genome sizes, wing dimensions and heart, flight muscle and body masses from a phylogenetically diverse set of bird species. In phylogenetically controlled analyses, we found that genome size was negatively correlated with relative flight muscle size and heart index (i.e. ratio of heart to body mass), but positively correlated with body mass and wing loading. The proportional masses of the flight muscles and heart were the most important parameters explaining variation in genome size in multivariate models. Hence, the metabolic intensity of powered flight appears to have driven genome size reduction in birds.

  20. Photometric Analysis and Physical Parameters for Six Mars-crossing and Ten Main-belt Asteroids from APT Observatory Group: 2017 April- September

    NASA Astrophysics Data System (ADS)

    Aznar Macias, Amadeo; Cornea, R.; Suciu, O.

    2018-01-01

    Lightcurves of six Mars-crossing and eight main-belt asteroids were obtained at APT-Observatory Group from 2017 April to September. In addition, two more asteroids were captured in 2014 and 2015 during the EURONEAR project. Analysis of rotation period, lightcurve amplitude, and physical parameters (size and axis size relationship) are presented.

  1. Designing to Fit People of Different Sizes: One Product Can Indeed Fit Nearly All People

    ERIC Educational Resources Information Center

    Reeder, Kevin

    2004-01-01

    People interact with products and vehicles in a physical manner. They push lawn mowers, they hold mixers, and they drive cars and trucks. This interaction is greatly improved when there is a physical, dimensional match between the people and the products and vehicles they use. However, people vary in size and shape. The study and application of…

  2. Physical activity and body image among men and boys: A meta-analysis.

    PubMed

    Bassett-Gunter, Rebecca; McEwan, Desmond; Kamarhie, Aria

    2017-09-01

    Three meta-analytic reviews have concluded that physical activity is positively related to body image. Historically, research regarding physical activity and body image has been disproportionately focused on female samples. For example, the most recent meta-analysis (2009) extracted 56 effect sizes for women and only 12 for men. The current paper provides an update to the literature regarding the relationship between physical activity and body image among men and boys across 84 individual effect sizes. The analysis also provides insight regarding moderator variables including participant age, and physical activity type and intensity. Overall, physical activity was positively related to body image among men and boys with various moderator variables warranting further investigation. Pragmatic implications are discussed as well as the limitations within existing research and need for additional research to further understand moderator and mediator variables. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Physical Education, Politics, and SPEAK Out! Day

    ERIC Educational Resources Information Center

    Claxton, David; Kopp, Rachael; Skidmore, Lauren; Williams, Kimberly

    2013-01-01

    This article discusses the importance of politics in the lives of physical educators. Politics affects many decisions that are made about physical education programs (PEPs). In public schools, politics can affect the number of certified physical education teachers, available facilities, class sizes, and number of days per week that students go to…

  4. 37 CFR 1.433 - Physical requirements of international application.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Physical requirements of... Provisions The International Application § 1.433 Physical requirements of international application. (a) The... must be on A4 size paper (21.0×29.7 cm.). (c) Other physical requirements for international...

  5. 37 CFR 1.433 - Physical requirements of international application.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Physical requirements of... Provisions The International Application § 1.433 Physical requirements of international application. (a) The... must be on A4 size paper (21.0 × 29.7 cm.). (c) Other physical requirements for international...

  6. 37 CFR 1.433 - Physical requirements of international application.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Physical requirements of... Provisions The International Application § 1.433 Physical requirements of international application. (a) The... must be on A4 size paper (21.0×29.7 cm.). (c) Other physical requirements for international...

  7. 37 CFR 1.433 - Physical requirements of international application.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Physical requirements of... Provisions The International Application § 1.433 Physical requirements of international application. (a) The... must be on A4 size paper (21.0 × 29.7 cm.). (c) Other physical requirements for international...

  8. 37 CFR 1.433 - Physical requirements of international application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Physical requirements of... Provisions The International Application § 1.433 Physical requirements of international application. (a) The... must be on A4 size paper (21.0×29.7 cm.). (c) Other physical requirements for international...

  9. The Correlation Between Small Dense LDL and Reactive Oxygen Metabolites in a Physical Activity Intervention in Hyperlipidemic Subjects.

    PubMed

    Kotani, Kazuhiko; Tsuzaki, Kokoro; Sakane, Naoki; Taniguchi, Nobuyuki

    2012-06-01

    Small dense low-density lipoprotein (sdLDL), which has a small LDL particle size with a greater susceptibility to oxidation, is considered a risk marker for cardiovascular disease (CVD). The diacron reactive oxygen metabolites (d-ROMs) have recently been introduced as a clinically useful oxidative stress-related marker. Physical activity can reduce the CVD risk. The present study investigated the correlation between the changes of the mean LDL particle size and the oxidative stress status, as assessed by the d-ROMs, in a physical activity intervention in hyperlipidemic subjects. We performed a 6-month intervention study of 30 hyperlipidemic subjects (12 male/18 female, mean age 64 years), focusing on a moderate physical activity increase. The clinical data, including the atherosclerotic risk factors besides the mean LDL particle size measured with the gel electrophoresis and the d-ROMs, were evaluated pre- and post-intervention. The mean LDL particle size was significantly larger in the post-intervention than in the pre-intervention evaluation (26.9 ± 0.3 (SD) vs. 27.1 ± 0.4 nm, P < 0.01), while the d-ROMs levels were significantly reduced in the post-intervention period compared to those at pre-intervention (319 ± 77 vs. 290 ± 73 U. Carr., P < 0.05). A stepwise multiple regression analysis revealed that there was an independent, significant and inverse correlation between the pre- and post-intervention changes of the d-ROMs and the mean LDL particle size (β = -0.55, P < 0.01). The intervention study suggests that sdLDL and oxidative stress can concomitantly affect the risk of developing CVD and that both factors can improve by even a moderate increase in physical activity among hyperlipidemic subjects.

  10. Physical characterization of whole and skim dried milk powders.

    PubMed

    Pugliese, Alessandro; Cabassi, Giovanni; Chiavaro, Emma; Paciulli, Maria; Carini, Eleonora; Mucchetti, Germano

    2017-10-01

    The lack of updated knowledge about the physical properties of milk powders aimed us to evaluate selected physical properties (water activity, particle size, density, flowability, solubility and colour) of eleven skim and whole milk powders produced in Europe. These physical properties are crucial both for the management of milk powder during the final steps of the drying process, and for their use as food ingredients. In general, except for the values of water activity, the physical properties of skim and whole milk powders are very different. Particle sizes of the spray-dried skim milk powders, measured as volume and surface mean diameter were significantly lower than that of the whole milk powders, while the roller dried sample showed the largest particle size. For all the samples the size distribution was quite narrow, with a span value less than 2. The loose density of skim milk powders was significantly higher than whole milk powders (541.36 vs 449.75 kg/m 3 ). Flowability, measured by Hausner ratio and Carr's index indicators, ranged from passable to poor when evaluated according to pharmaceutical criteria. The insolubility index of the spray-dried skim and whole milk powders, measured as weight of the sediment (from 0.5 to 34.8 mg), allowed a good discrimination of the samples. Colour analysis underlined the relevant contribution of fat content and particle size, resulted in higher lightness ( L *) for skim milk powder than whole milk powder, which, on the other hand, showed higher yellowness ( b *) and lower greenness (- a *). In conclusion a detailed knowledge of functional properties of milk powders may allow the dairy to tailor the products to the user and help the food processor to perform a targeted choice according to the intended use.

  11. Fundamental Physical Limits for the Size of Future Planetary Surface Exploration Systems

    NASA Astrophysics Data System (ADS)

    Andrews, F.; Hobbs, S. E.; Honstvet, I.; Snelling, M.

    2004-04-01

    With the current interest in the potential use of Nanotechnology for spacecraft, it becomes increasingly likely that environmental sensor probes, such as the "lab-on-a-chip" concept, will take advantage of this technology and become orders of magnitude smaller than current sensor systems. This paper begins to investigate how small these systems could theoretically become, and what are the governing laws and limiting factors that determine that minimum size. The investigation focuses on the three primary subsystems for a sensor network of this nature Sensing, Information Processing and Communication. In general, there are few fundamental physical laws that limit the size of the sensor system. Limits tend to be driven by factors other than the laws of physics. These include user requirements, such as the acceptable probability of error, and the potential external environment.

  12. Lattice-Mismatch-Induced Oscillatory Feature Size and Its Impact on the Physical Limitation of Grain Size

    NASA Astrophysics Data System (ADS)

    Deng, Jinyu; Li, Huihui; Dong, Kaifeng; Li, Run-Wei; Peng, Yingguo; Ju, Ganping; Hu, Jiangfeng; Chow, Gan Moog; Chen, Jingsheng

    2018-03-01

    We find that the misfit strain may lead to the oscillatory size distributions of heteroepitaxial nanostructures. In heteroepitaxial FePt thin films grown on single-crystal MgO substrate, ⟨110 ⟩ -oriented mazelike and granular patterns with "quantized" feature sizes are realized in scanning-electron-microscope images. The physical mechanism responsible for the size oscillations is related to the oscillatory nature of the misfit strain energy in the domain-matching epitaxial FePt /MgO system, which is observed by transmission electron microscopy. Based on the experimental observations, a model is built and the results suggest that when the FePt island sizes are an integer times the misfit dislocation period, the misfit strain can be completely canceled by the misfit dislocations. With applying the mechanism, small and uniform grain is obtained on the TiN (200) polycrystalline underlayer, which is suitable for practical application. This finding may offer a way to synthesize nanostructured materials with well-controlled size and size distribution by tuning the lattice mismatch between the epitaxial-grown heterostructure.

  13. Physical activity text messaging interventions in adults: a systematic review.

    PubMed

    Buchholz, Susan Weber; Wilbur, JoEllen; Ingram, Diana; Fogg, Louis

    2013-08-01

    Physical inactivity is a leading health risk factor for mortality worldwide. Researchers are examining innovative techniques including the use of mobile technology to promote physical activity. One such technology, text messaging, is emerging internationally as a method to communicate with and motivate individuals to engage in healthy behaviors, including physical activity. Review the existing scientific literature on adult physical activity text messaging interventions. This systematic review examined research papers that addressed physical activity text messaging intervention studies in adults. Using multiple databases, the search strategy included published English language studies through October 1, 2011. An author-developed data collection tool was used independently by two reviewers to extract and examine the selected study variables. The initial search resulted in the identification of 200 publications. Eleven publications representing 10 studies were included in the final review. Studies were conducted in seven countries with over half the studies being randomized controlled trials. Participants of the studies were predominantly young to middle aged women. Physical activity data were mainly obtained by self-report although three studies used pedometers or accelerometers. Interventions ranged from only sending out text messages to combining text messages with educational materials, staff support, and/or Internet technology. Minimal information was given regarding development or number of text messages used. The median effect size for the studies was 0.50. To date, using text messaging as a method to promote physical activity has only been studied by a small group of researchers. Current physical activity text messaging literature is characterized by small sample sizes, heterogeneous but positive effect sizes, and a lack of specificity as to the development of the text messages used in these studies. Further research in this area is imperative to facilitate the expansion of mobile technology to promote physical activity. © 2013 Sigma Theta Tau International.

  14. Influence of physical activity on vertebral strength during late adolescence.

    PubMed

    Junno, Juho-Antti; Paananen, Markus; Karppinen, Jaro; Tammelin, Tuija; Niinimäki, Jaakko; Lammentausta, Eveliina; Niskanen, Markku; Nieminen, Miika T; Järvelin, Marjo-Riitta; Takatalo, Jani; Tervonen, Osmo; Tuukkanen, Juha

    2013-02-01

    Reduced vertebral strength is a clear risk factor for vertebral fractures. Men and women with vertebral fractures often have reduced vertebral size and bone mineral density (BMD). Vertebral strength is controlled by both genetic and developmental factors. Malnutrition and low levels of physical activity are commonly considered to result in reduced bone size during growth. Several studies have also demonstrated the general relationship between BMD and physical activity in the appendicular skeleton. In this study, we wanted to clarify the role of physical activity on vertebral bodies. Vertebral dimensions appear to generally be less pliant than long bones when lifetime changes occur. We wanted to explore the association between physical activity during late adolescence and vertebral strength parameters such as cross-sectional size and BMD. The association between physical activity and vertebral strength was explored by measuring vertebral strength parameters and defining the level of physical activity during adolescence. The study population consisted of 6,928 males and females who, at 15 to 16 and 19 years of age, responded to a mailed questionnaire inquiring about their physical activity. A total of 558 individuals at the mean age of 21 years underwent magnetic resonance imaging (MRI) scans. We measured the dimensions of the fourth lumbar vertebra from the MRI scans of the Northern Finland Birth Cohort 1986 and performed T2* relaxation time mapping, reflective of BMD. Vertebral strength was based on these two parameters. We analyzed the association of physical activity on vertebral strength using the analysis of variance. We observed no association between the level of physical activity during late adolescence and vertebral strength at 21 years. Copyright © 2013 Elsevier Inc. All rights reserved.

  15. QA/QC requirements for physical properties sampling and analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Innis, B.E.

    1993-07-21

    This report presents results of an assessment of the available information concerning US Environmental Protection Agency (EPA) quality assurance/quality control (QA/QC) requirements and guidance applicable to sampling, handling, and analyzing physical parameter samples at Comprehensive Environmental Restoration, Compensation, and Liability Act (CERCLA) investigation sites. Geotechnical testing laboratories measure the following physical properties of soil and sediment samples collected during CERCLA remedial investigations (RI) at the Hanford Site: moisture content, grain size by sieve, grain size by hydrometer, specific gravity, bulk density/porosity, saturated hydraulic conductivity, moisture retention, unsaturated hydraulic conductivity, and permeability of rocks by flowing air. Geotechnical testing laboratories alsomore » measure the following chemical parameters of soil and sediment samples collected during Hanford Site CERCLA RI: calcium carbonate and saturated column leach testing. Physical parameter data are used for (1) characterization of vadose and saturated zone geology and hydrogeology, (2) selection of monitoring well screen sizes, (3) to support modeling and analysis of the vadose and saturated zones, and (4) for engineering design. The objectives of this report are to determine the QA/QC levels accepted in the EPA Region 10 for the sampling, handling, and analysis of soil samples for physical parameters during CERCLA RI.« less

  16. What are the most effective intervention techniques for changing physical activity self-efficacy and physical activity behaviour--and are they the same?

    PubMed

    Williams, S L; French, D P

    2011-04-01

    There is convincing evidence that targeting self-efficacy is an effective means of increasing physical activity. However, evidence concerning which are the most effective techniques for changing self-efficacy and thereby physical activity is lacking. The present review aims to estimate the association between specific intervention techniques used in physical activity interventions and change obtained in both self-efficacy and physical activity behaviour. A systematic search yielded 27 physical activity intervention studies for 'healthy' adults that reported self-efficacy and physical activity data. A small, yet significant (P < 0.01) effect of the interventions was found on change in self-efficacy and physical activity (d = 0.16 and 0.21, respectively). When a technique was associated with a change in effect sizes for self-efficacy, it also tended to be associated with a change (r(s) = 0.690, P < 0.001) in effect size for physical activity. Moderator analyses found that 'action planning', 'provide instruction' and 'reinforcing effort towards behaviour' were associated with significantly higher levels of both self-efficacy and physical activity. 'Relapse prevention' and 'setting graded tasks' were associated with significantly lower self-efficacy and physical activity levels. This meta-analysis provides evidence for which psychological techniques are most effective for changing self-efficacy and physical activity.

  17. Remote sensing of atmospheric particulates: Technological innovation and physical limitations in applications to short-range weather prediction

    NASA Technical Reports Server (NTRS)

    Curran, R. J.; Kropfil, R.; Hallett, J.

    1984-01-01

    Techniques for remote sensing of particles, from cloud droplet to hailstone size, using optical and microwave frequencies are reviewed. The inherent variability of atmospheric particulates is examined to delineate conditions when the signal can give information to be effectively utilized in a forecasting context. The physical limitations resulting from the phase, size, orientation and concentration variability of the particulates are assessed.

  18. A meta-analysis of active video games on health outcomes among children and adolescents.

    PubMed

    Gao, Z; Chen, S; Pasco, D; Pope, Z

    2015-09-01

    This meta-analysis synthesizes current literature concerning the effects of active video games (AVGs) on children/adolescents' health-related outcomes. A total of 512 published studies on AVGs were located, and 35 articles were included based on the following criteria: (i) data-based research articles published in English between 1985 and 2015; (ii) studied some types of AVGs and related outcomes among children/adolescents and (iii) had at least one comparison within each study. Data were extracted to conduct comparisons for outcome measures in three separate categories: AVGs and sedentary behaviours, AVGs and laboratory-based exercise, and AVGs and field-based physical activity. Effect size for each entry was calculated with the Comprehensive Meta-Analysis software in 2015. Mean effect size (Hedge's g) and standard deviation were calculated for each comparison. Compared with sedentary behaviours, AVGs had a large effect on health outcomes. The effect sizes for physiological outcomes were marginal when comparing AVGs with laboratory-based exercises. The comparison between AVGs and field-based physical activity had null to moderate effect sizes. AVGs could yield equivalent health benefits to children/adolescents as laboratory-based exercise or field-based physical activity. Therefore, AVGs can be a good alternative for sedentary behaviour and addition to traditional physical activity and sports in children/adolescents. © 2015 World Obesity.

  19. Physically based method for measuring suspended-sediment concentration and grain size using multi-frequency arrays of acoustic-doppler profilers

    USGS Publications Warehouse

    Topping, David J.; Wright, Scott A.; Griffiths, Ronald; Dean, David

    2014-01-01

    As the result of a 12-year program of sediment-transport research and field testing on the Colorado River (6 stations in UT and AZ), Yampa River (2 stations in CO), Little Snake River (1 station in CO), Green River (1 station in CO and 2 stations in UT), and Rio Grande (2 stations in TX), we have developed a physically based method for measuring suspended-sediment concentration and grain size at 15-minute intervals using multifrequency arrays of acoustic-Doppler profilers. This multi-frequency method is able to achieve much higher accuracies than single-frequency acoustic methods because it allows removal of the influence of changes in grain size on acoustic backscatter. The method proceeds as follows. (1) Acoustic attenuation at each frequency is related to the concentration of silt and clay with a known grain-size distribution in a river cross section using physical samples and theory. (2) The combination of acoustic backscatter and attenuation at each frequency is uniquely related to the concentration of sand (with a known reference grain-size distribution) and the concentration of silt and clay (with a known reference grain-size distribution) in a river cross section using physical samples and theory. (3) Comparison of the suspended-sand concentrations measured at each frequency using this approach then allows theory-based calculation of the median grain size of the suspended sand and final correction of the suspended-sand concentration to compensate for the influence of changing grain size on backscatter. Although this method of measuring suspended-sediment concentration is somewhat less accurate than using conventional samplers in either the EDI or EWI methods, it is much more accurate than estimating suspended-sediment concentrations using calibrated pump measurements or single-frequency acoustics. Though the EDI and EWI methods provide the most accurate measurements of suspended-sediment concentration, these measurements are labor-intensive, expensive, and may be impossible to collect at time intervals less than discharge-independent changes in suspended-sediment concentration can occur (< hours). Therefore, our physically based multi-frequency acoustic method shows promise as a cost-effective, valid approach for calculating suspended-sediment loads in river at a level of accuracy sufficient for many scientific and management purposes.

  20. Effect of composition on physical properties of food powders

    NASA Astrophysics Data System (ADS)

    Szulc, Karolina; Lenart, Andrzej

    2016-04-01

    The paper presents an influence of raw material composition and technological process applied on selected physical properties of food powders. Powdered multi-component nutrients were subjected to the process of mixing, agglomeration, coating, and drying. Wetting liquids ie water and a 15% water lactose solution, were used in agglomeration and coating. The analyzed food powders were characterized by differentiated physical properties, including especially: particle size, bulk density, wettability, and dispersibility. The raw material composition of the studied nutrients exerted a statistically significant influence on their physical properties. Agglomeration as well as coating of food powders caused a significant increase in particle size, decreased bulk density, increased apparent density and porosity, and deterioration in flowability in comparison with non-agglomerated nutrients.

  1. Radiopacifier Particle Size Impacts the Physical Properties of Tricalcium Silicate–based Cements

    PubMed Central

    Saghiri, Mohammad Ali; Gutmann, James L.; Orangi, Jafar; Asatourian, Armen; Sheibani, Nader

    2016-01-01

    Introduction The aim of this study was to evaluate the impact of radiopaque additive, bismuth oxide, particle size on the physical properties, and radiopacity of tricalcium silicate–based cements. Methods Six types of tricalcium silicate cement (CSC) including CSC without bismuth oxide, CSC + 10% (wt%) regular bismuth oxide (particle size 10 μm), CSC + 20% regular bismuth oxide (simulating white mineral trioxide aggregate [WMTA]) as a control, CSC + 10% nano bismuth oxide (particle size 50–80 nm), CSC + 20% nano-size bismuth oxide, and nano WMTA (a nano modification of WMTA comprising nanoparticles in the range of 40–100 nm) were prepared. Twenty-four samples from each group were divided into 4 groups and subjected to push-out, surface microhardness, radiopacity, and compressive strength tests. Data were analyzed by 1-way analysis of variance with the post hoc Tukey test. Results The push-out and compressive strength of CSC without bismuth oxide and CSC with 10% and 20% nano bismuth oxide were significantly higher than CSC with 10% or 20% regular bismuth oxide (P < .05). The surface micro-hardness of CSC without bismuth oxide and CSC with 10% regular bismuth oxide had the lowest values (P < .05). The lowest radiopacity values were seen in CSC without bismuth oxide and CSC with 10% nano bismuth oxide (P < .05). Nano WMTA samples showed the highest values for all tested properties (P < .05) except for radiopacity. Conclusions The addition of 20% nano bismuth oxide enhanced the physical properties of CSC without any significant changes in radiopacity. Regular particle-size bismuth oxide reduced the physical properties of CSC material for tested parameters. PMID:25492489

  2. Physical Selectivity of Molecularly Imprinted polymers evaluated through free volume size distributions derived from Positron Lifetime Spectroscopy

    NASA Astrophysics Data System (ADS)

    Pasang, T.; Ranganathaiah, C.

    2015-06-01

    The technique of imprinting molecules of various sizes in a stable structure of polymer matrix has derived multitudes of applications. Once the template molecule is extracted from the polymer matrix, it leaves behind a cavity which is physically (size and shape) and chemically (functional binding site) compatible to the particular template molecule. Positron Annihilation Lifetime Spectroscopy (PALS) is a well known technique to measure cavity sizes precisely in the nanoscale and is not being used in the field of MIPs effectively. This method is capable of measuring nanopores and hence suitable to understand the physical selectivity of the MIPs better. With this idea in mind, we have prepared molecular imprinted polymers (MIPs) with methacrylicacid (MAA) as monomer and EGDMA as cross linker in different molar ratio for three different size template molecules, viz. 4-Chlorophenol (4CP)(2.29 Å), 2-Nephthol (2NP) (3.36 Å) and Phenolphthalein (PP) (4.47Å). FTIR and the dye chemical reactions are used to confirm the complete extraction of the template molecules from the polymer matrix. The free volume size and its distribution have been derived from the measured o-Ps lifetime spectra. Based on the free volume distribution analysis, the percentage of functional cavities for the three template molecules are determined. Percentage of functional binding cavities for 4-CP molecules has been found out to be 70.2% and the rest are native cavities. Similarly for 2NP it is 81.5% and nearly 100% for PP. Therefore, PALS method proves to be very precise and accurate for determining the physical selectivity of MIPs.

  3. Owning an overweight or underweight body: distinguishing the physical, experienced and virtual body.

    PubMed

    Piryankova, Ivelina V; Wong, Hong Yu; Linkenauger, Sally A; Stinson, Catherine; Longo, Matthew R; Bülthoff, Heinrich H; Mohler, Betty J

    2014-01-01

    Our bodies are the most intimately familiar objects we encounter in our perceptual environment. Virtual reality provides a unique method to allow us to experience having a very different body from our own, thereby providing a valuable method to explore the plasticity of body representation. In this paper, we show that women can experience ownership over a whole virtual body that is considerably smaller or larger than their physical body. In order to gain a better understanding of the mechanisms underlying body ownership, we use an embodiment questionnaire, and introduce two new behavioral response measures: an affordance estimation task (indirect measure of body size) and a body size estimation task (direct measure of body size). Interestingly, after viewing the virtual body from first person perspective, both the affordance and the body size estimation tasks indicate a change in the perception of the size of the participant's experienced body. The change is biased by the size of the virtual body (overweight or underweight). Another novel aspect of our study is that we distinguish between the physical, experienced and virtual bodies, by asking participants to provide affordance and body size estimations for each of the three bodies separately. This methodological point is important for virtual reality experiments investigating body ownership of a virtual body, because it offers a better understanding of which cues (e.g. visual, proprioceptive, memory, or a combination thereof) influence body perception, and whether the impact of these cues can vary between different setups.

  4. Owning an Overweight or Underweight Body: Distinguishing the Physical, Experienced and Virtual Body

    PubMed Central

    Piryankova, Ivelina V.; Wong, Hong Yu; Linkenauger, Sally A.; Stinson, Catherine; Longo, Matthew R.; Bülthoff, Heinrich H.; Mohler, Betty J.

    2014-01-01

    Our bodies are the most intimately familiar objects we encounter in our perceptual environment. Virtual reality provides a unique method to allow us to experience having a very different body from our own, thereby providing a valuable method to explore the plasticity of body representation. In this paper, we show that women can experience ownership over a whole virtual body that is considerably smaller or larger than their physical body. In order to gain a better understanding of the mechanisms underlying body ownership, we use an embodiment questionnaire, and introduce two new behavioral response measures: an affordance estimation task (indirect measure of body size) and a body size estimation task (direct measure of body size). Interestingly, after viewing the virtual body from first person perspective, both the affordance and the body size estimation tasks indicate a change in the perception of the size of the participant's experienced body. The change is biased by the size of the virtual body (overweight or underweight). Another novel aspect of our study is that we distinguish between the physical, experienced and virtual bodies, by asking participants to provide affordance and body size estimations for each of the three bodies separately. This methodological point is important for virtual reality experiments investigating body ownership of a virtual body, because it offers a better understanding of which cues (e.g. visual, proprioceptive, memory, or a combination thereof) influence body perception, and whether the impact of these cues can vary between different setups. PMID:25083784

  5. Influence of particle size on physical and sensory attributes of mango pulp powder

    NASA Astrophysics Data System (ADS)

    Sharma, M.; Kadam, D. M.; Chadha, S.; Wilson, R. A.; Gupta, R. K.

    2013-09-01

    The present investigation was aimed to observe the effect of particle size on physical, sensory and thermal properties of foam-mat dried mango pulp powder. Mango pulp of Dussehri variety was foam-mat dried using 3% egg white at 65ºC. Dried foam-mats were pulverized and passed through a sieve shaker for obtaining three grades of powder with 50, 60, and 85 mesh size sieves. The particle size of these samples measured using laser diffraction particle size analyzer ranged from 191.26 to 296.19 μm. The data was analysed statistically using ANOVA of SAS. There was a linear increase in lightness (`L' value) with a decrease in particle size, however, `a' value decreased with a decrease in particle size, indicating the decrease in redness. An increase in bulk density and decrease in water solubility index and water absorption index % were observed with a decrease in particle size. Particle size had a significant effect on sensory parameters. Particle size in the range of 258.01 to 264.60μmwas found most acceptable with respect to sensory characteristics. This finding can be exploited for various commercial applicationswhere powder quality is dependent on the particle size and has foremost priority for end users.

  6. Physical therapy treatments for low back pain in children and adolescents: a meta-analysis

    PubMed Central

    2013-01-01

    Background Low back pain (LBP) in adolescents is associated with LBP in later years. In recent years treatments have been administered to adolescents for LBP, but it is not known which physical therapy treatment is the most efficacious. By means of a meta-analysis, the current study investigated the effectiveness of the physical therapy treatments for LBP in children and adolescents. Methods Studies in English, Spanish, French, Italian and Portuguese, and carried out by March 2011, were selected by electronic and manual search. Two independent researchers coded the moderator variables of the studies, and performed the effect size calculations. The mean effect size index used was the standardized mean change between the pretest and posttest, and it was applied separately for each combination of outcome measures, (pain, disability, flexibility, endurance and mental health) and measurement type (self-reports, and clinician assessments). Results Eight articles that met the selection criteria enabled us to define 11 treatment groups and 5 control groups using the group as the unit of analysis. The 16 groups involved a total sample of 334 subjects at the posttest (221 in the treatment groups and 113 in the control groups). For all outcome measures, the average effect size of the treatment groups was statistically and clinically significant, whereas the control groups had negative average effect sizes that were not statistically significant. Conclusions Of all the physical therapy treatments for LBP in children and adolescents, the combination of therapeutic physical conditioning and manual therapy is the most effective. The low number of studies and control groups, and the methodological limitations in this meta-analysis prevent us from drawing definitive conclusions in relation to the efficacy of physical therapy treatments in LBP. PMID:23374375

  7. Physical therapy treatments for low back pain in children and adolescents: a meta-analysis.

    PubMed

    Calvo-Muñoz, Inmaculada; Gómez-Conesa, Antonia; Sánchez-Meca, Julio

    2013-02-02

    Low back pain (LBP) in adolescents is associated with LBP in later years. In recent years treatments have been administered to adolescents for LBP, but it is not known which physical therapy treatment is the most efficacious. By means of a meta-analysis, the current study investigated the effectiveness of the physical therapy treatments for LBP in children and adolescents. Studies in English, Spanish, French, Italian and Portuguese, and carried out by March 2011, were selected by electronic and manual search. Two independent researchers coded the moderator variables of the studies, and performed the effect size calculations. The mean effect size index used was the standardized mean change between the pretest and posttest, and it was applied separately for each combination of outcome measures, (pain, disability, flexibility, endurance and mental health) and measurement type (self-reports, and clinician assessments). Eight articles that met the selection criteria enabled us to define 11 treatment groups and 5 control groups using the group as the unit of analysis. The 16 groups involved a total sample of 334 subjects at the posttest (221 in the treatment groups and 113 in the control groups). For all outcome measures, the average effect size of the treatment groups was statistically and clinically significant, whereas the control groups had negative average effect sizes that were not statistically significant. Of all the physical therapy treatments for LBP in children and adolescents, the combination of therapeutic physical conditioning and manual therapy is the most effective. The low number of studies and control groups, and the methodological limitations in this meta-analysis prevent us from drawing definitive conclusions in relation to the efficacy of physical therapy treatments in LBP.

  8. Primary Class Size Reduction: How Policy Space, Physical Space, and Spatiality Shape What Happens in Real Schools

    ERIC Educational Resources Information Center

    Bascia, Nina; Faubert, Brenton

    2012-01-01

    This article reviews the literature base on class size reduction and proposes a new analytic framework that we believe provides practically useful explanations of how primary class size reduction works. It presents descriptions of classroom practice and grounded explanations for how class size reduction affects educational core activities by…

  9. Arsenic Adsorption and As (III) Oxidation on TiO2 Nanoparticles: Macroscopic and Spectroscopic Investigations

    EPA Science Inventory

    Engineered nanoparticles (NPs) (particle sizes ranging from 1-100 nm) have unique physical and chemical properties that differ fundamentally from their macro-sized counterparts. In addition to their smaller particle size, nanoparticles possess unique characteristics such as larg...

  10. 36 CFR 67.7 - Standards for rehabilitation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... be substantiated by documentary, physical, or pictorial evidence. (7) Chemical or physical treatments... features. The Standards pertain to historic buildings of all materials, construction types, sizes, and... a physical record of its time, place, and use. Changes that create a false sense of historical...

  11. 36 CFR 67.7 - Standards for rehabilitation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... be substantiated by documentary, physical, or pictorial evidence. (7) Chemical or physical treatments... features. The Standards pertain to historic buildings of all materials, construction types, sizes, and... a physical record of its time, place, and use. Changes that create a false sense of historical...

  12. 36 CFR 67.7 - Standards for rehabilitation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... be substantiated by documentary, physical, or pictorial evidence. (7) Chemical or physical treatments... features. The Standards pertain to historic buildings of all materials, construction types, sizes, and... a physical record of its time, place, and use. Changes that create a false sense of historical...

  13. 36 CFR 67.7 - Standards for rehabilitation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... be substantiated by documentary, physical, or pictorial evidence. (7) Chemical or physical treatments... features. The Standards pertain to historic buildings of all materials, construction types, sizes, and... a physical record of its time, place, and use. Changes that create a false sense of historical...

  14. Enhancement and degradation of the R2* relaxation rate resulting from the encapsulation of magnetic particles with hydrophilic coatings.

    PubMed

    de Haan, Hendrick W; Paquet, Chantal

    2011-12-01

    The effects of including a hydrophilic coating around the particles are studied across a wide range of particle sizes by performing Monte Carlo simulations of protons diffusing through a system of magnetic particles. A physically realistic methodology of implementing the coating by cross boundary jump scaling and transition probabilities at the coating surface is developed. Using this formulation, the coating has three distinct impacts on the relaxation rate: an enhancement at small particle sizes, a degradation at intermediate particle sizes, and no effect at large particles sizes. These varied effects are reconciled with the underlying dephasing mechanisms by using the concept of a full dephasing zone to present a physical picture of the dephasing process with and without the coating for all sizes. The enhancement at small particle sizes is studied systemically to demonstrate the existence of an optimal ratio of diffusion coefficients inside/outside the coating to achieve maximal increase in the relaxation rate. Copyright © 2011 Wiley Periodicals, Inc.

  15. Perspective Space as a Model for Distance and Size Perception.

    PubMed

    Erkelens, Casper J

    2017-01-01

    In the literature, perspective space has been introduced as a model of visual space. Perspective space is grounded on the perspective nature of visual space during both binocular and monocular vision. A single parameter, that is, the distance of the vanishing point, transforms the geometry of physical space into that of perspective space. The perspective-space model predicts perceived angles, distances, and sizes. The model is compared with other models for distance and size perception. Perspective space predicts that perceived distance and size as a function of physical distance are described by hyperbolic functions. Alternatively, power functions have been widely used to describe perceived distance and size. Comparison of power and hyperbolic functions shows that both functions are equivalent within the range of distances that have been judged in experiments. Two models describing perceived distance on the ground plane appear to be equivalent with the perspective-space model too. The conclusion is that perspective space unifies a number of models of distance and size perception.

  16. Perspective Space as a Model for Distance and Size Perception

    PubMed Central

    2017-01-01

    In the literature, perspective space has been introduced as a model of visual space. Perspective space is grounded on the perspective nature of visual space during both binocular and monocular vision. A single parameter, that is, the distance of the vanishing point, transforms the geometry of physical space into that of perspective space. The perspective-space model predicts perceived angles, distances, and sizes. The model is compared with other models for distance and size perception. Perspective space predicts that perceived distance and size as a function of physical distance are described by hyperbolic functions. Alternatively, power functions have been widely used to describe perceived distance and size. Comparison of power and hyperbolic functions shows that both functions are equivalent within the range of distances that have been judged in experiments. Two models describing perceived distance on the ground plane appear to be equivalent with the perspective-space model too. The conclusion is that perspective space unifies a number of models of distance and size perception. PMID:29225765

  17. Unravelling the physics of size-dependent dislocation-mediated plasticity

    NASA Astrophysics Data System (ADS)

    El-Awady, Jaafar A.

    2015-01-01

    Size-affected dislocation-mediated plasticity is important in a wide range of materials and technologies. Here we develop a generalized size-dependent dislocation-based model that predicts strength as a function of crystal/grain size and the dislocation density. Three-dimensional (3D) discrete dislocation dynamics (DDD) simulations reveal the existence of a well-defined relationship between strength and dislocation microstructure at all length scales for both single crystals and polycrystalline materials. The results predict a transition from dislocation-source strengthening to forest-dominated strengthening at a size-dependent critical dislocation density. It is also shown that the Hall-Petch relationship can be physically interpreted by coupling with an appropriate kinetic equation of the evolution of the dislocation density in polycrystals. The model is shown to be in remarkable agreement with experiments. This work presents a micro-mechanistic framework to predict and interpret strength size-scale effects, and provides an avenue towards performing multiscale simulations without ad hoc assumptions.

  18. On the internal representation of numerical magnitude and physical size.

    PubMed

    Fitousi, Daniel

    2014-01-01

    A nascent idea in the numerical cognition literature--the analogical hypothesis (Pinel, Piazza, Bihan, & Dehaene, 2004)--assumes a common noisy code for the representation of symbolic (e.g., numerals) and nonsymbolic (e.g., numerosity, physical size, luminance) magnitudes. The present work subjected this assumption to various tests from the perspective of General Recognition Theory (GRT; Ashby &Townsend, 1986)--a multidimensional extension of Signal Detection Theory (Green & Swets, 1966). The GRT was applied to the dimensions of numerical magnitude and physical size with the following goals: (a) characterizing the internal representation of these dimensions in the psychological space, and (b) assessing various types of (in)dependence and separability governing the perception of these dimensions. The results revealed various violations of independence and separability with Stroop incongruent, but not with Stroop congruent stimuli. The outcome suggests that there are deep differences in architecture between Stroop congruent and incongruent stimuli that reach well beyond the semantic relationship involved.

  19. Atmospheric cloud physics laboratory project study

    NASA Technical Reports Server (NTRS)

    Schultz, W. E.; Stephen, L. A.; Usher, L. H.

    1976-01-01

    Engineering studies were performed for the Zero-G Cloud Physics Experiment liquid cooling and air pressure control systems. A total of four concepts for the liquid cooling system was evaluated, two of which were found to closely approach the systems requirements. Thermal insulation requirements, system hardware, and control sensor locations were established. The reservoir sizes and initial temperatures were defined as well as system power requirements. In the study of the pressure control system, fluid analyses by the Atmospheric Cloud Physics Laboratory were performed to determine flow characteristics of various orifice sizes, vacuum pump adequacy, and control systems performance. System parameters predicted in these analyses as a function of time include the following for various orifice sizes: (1) chamber and vacuum pump mass flow rates, (2) the number of valve openings or closures, (3) the maximum cloud chamber pressure deviation from the allowable, and (4) cloud chamber and accumulator pressure.

  20. Automated sampling assessment for molecular simulations using the effective sample size

    PubMed Central

    Zhang, Xin; Bhatt, Divesh; Zuckerman, Daniel M.

    2010-01-01

    To quantify the progress in the development of algorithms and forcefields used in molecular simulations, a general method for the assessment of the sampling quality is needed. Statistical mechanics principles suggest the populations of physical states characterize equilibrium sampling in a fundamental way. We therefore develop an approach for analyzing the variances in state populations, which quantifies the degree of sampling in terms of the effective sample size (ESS). The ESS estimates the number of statistically independent configurations contained in a simulated ensemble. The method is applicable to both traditional dynamics simulations as well as more modern (e.g., multi–canonical) approaches. Our procedure is tested in a variety of systems from toy models to atomistic protein simulations. We also introduce a simple automated procedure to obtain approximate physical states from dynamic trajectories: this allows sample–size estimation in systems for which physical states are not known in advance. PMID:21221418

  1. The effect of different physical activity levels on muscle fiber size and type distribution of lumbar multifidus. A biopsy study on low back pain patient groups and healthy control subjects.

    PubMed

    Mazis, N; Papachristou, D J; Zouboulis, P; Tyllianakis, M; Scopa, C D; Megas, P

    2009-12-01

    Previous studies examining the multifidus fiber characteristics among low back pain (LBP) patients have not considered the variable of physical activity. The present study sought to investigate the muscle fiber size and type distribution of the lumbar multifidus muscle among LBP patient groups with different physical activity levels and healthy controls. Sixty-four patients were assigned to one of three groups named according to the physical activity level, determined for each patient by the International Physical Activity Questionnaire. These were low (LPA), medium (MPA) and high (HPA) physical activity groups. A control group comprising of 17 healthy individuals was also recruited. Muscle biopsy samples were obtained from the multifidus muscle at the level L4-L5. contrast with the control group, LBP patient groups showed a significantly higher Type II fiber distribution as well as reduced diameter in both fiber types (P<0.05). The physical activity level did not have an effect on multifidus characteristics since no significant differences were observed in fiber type and diameter (P>0.05) among LPA, MPA and HPA patient groups. Various pathological conditions were detected which were more pronounced in LBP groups compared to the control (P<0.05). Males had a larger fiber diameter compared to females for both fiber types (P<0.05). The results showed that the level of physical activity did not affect muscle fiber size and type distribution among LBP patients groups. These findings suggest that not only inactivity but also high physical activity levels can have an adverse effect on the multifidus muscle fiber characteristics.

  2. Pattern Recognition and Size Prediction of Microcalcification Based on Physical Characteristics by Using Digital Mammogram Images.

    PubMed

    Jothilakshmi, G R; Raaza, Arun; Rajendran, V; Sreenivasa Varma, Y; Guru Nirmal Raj, R

    2018-06-05

    Breast cancer is one of the life-threatening cancers occurring in women. In recent years, from the surveys provided by various medical organizations, it has become clear that the mortality rate of females is increasing owing to the late detection of breast cancer. Therefore, an automated algorithm is needed to identify the early occurrence of microcalcification, which would assist radiologists and physicians in reducing the false predictions via image processing techniques. In this work, we propose a new algorithm to detect the pattern of a microcalcification by calculating its physical characteristics. The considered physical characteristics are the reflection coefficient and mass density of the binned digital mammogram image. The calculation of physical characteristics doubly confirms the presence of malignant microcalcification. Subsequently, by interpolating the physical characteristics via thresholding and mapping techniques, a three-dimensional (3D) projection of the region of interest (RoI) is obtained in terms of the distance in millimeter. The size of a microcalcification is determined using this 3D-projected view. This algorithm is verified with 100 abnormal mammogram images showing microcalcification and 10 normal mammogram images. In addition to the size calculation, the proposed algorithm acts as a good classifier that is used to classify the considered input image as normal or abnormal with the help of only two physical characteristics. This proposed algorithm exhibits a classification accuracy of 99%.

  3. Size matters: the interplay between sensing and size in aquatic environments

    NASA Astrophysics Data System (ADS)

    Wadhwa, Navish; Martens, Erik A.; Lindemann, Christian; Jacobsen, Nis S.; Andersen, Ken H.; Visser, Andre

    2015-11-01

    Sensing the presence or absence of other organisms in the surroundings is critical for the survival of any aquatic organism. This is achieved via the use of various sensory modes such as chemosensing, mechanosensing, vision, hearing, and echolocation. We ask how the size of an organism determines what sensory modes are available to it while others are not. We investigate this by examining the physical laws governing signal generation, transmission, and reception, together with the limits set by physiology. Hydrodynamics plays an important role in sensing; in particular chemosensing and mechanosensing are constrained by the physics of fluid motion at various scales. Through our analysis, we find a hierarchy of sensing modes determined by body size. We theoretically predict the body size limits for various sensory modes, which align well with size ranges found in the literature. Our analysis of all ocean life, from unicellular organisms to whales, demonstrates how body size determines available sensing modes, and thereby acts as a major structuring factor of aquatic life. The Centre for Ocean Life is a VKR center of excellence supported by the Villum Foundation.

  4. Assessing Learning in Small Sized Physics Courses

    ERIC Educational Resources Information Center

    Ene, Emanuela; Ackerson, Bruce J.

    2018-01-01

    We describe the construction, validation, and testing of a concept inventory for an "Introduction to Physics of Semiconductors" course offered by the department of physics to undergraduate engineering students. By design, this inventory addresses both content knowledge and the ability to interpret content via different cognitive…

  5. The effect of remediation on reducing misconception: a metaanalysis of student thesis on physics education

    NASA Astrophysics Data System (ADS)

    Oktavianty, E.; Haratua, T. M. S.; Anuru, M.

    2018-05-01

    The purpose of this study is to compare the effects of various remediation practices in reducing the number of student misconceptions on physics concepts. This research synthesizes 68 thesis undergraduate students of physics education which are published in Tanjungpura University library 2009-2016 period. In this study, the guidance in the form of checklist in conducting the study arranged to facilitate the understanding and assessment of the scientific work. Based on the analysis result, the average of effect size of all the synthesized thesis is 1.13. There are six forms of remedial misconceptions performed by physics education students, such as re-learning, feedback, integration of remediation in learning, physical activity, utilization of other learning resources and interviews. In addition, sampling techniques and test reliability were have contributed to the effect size of the study. Therefore, it is expected that the results of this study can be considered in preparing the remediation of misconceptions on physics learning in the future.

  6. Verification of the Icarus Material Response Tool

    NASA Technical Reports Server (NTRS)

    Schroeder, Olivia; Palmer, Grant; Stern, Eric; Schulz, Joseph; Muppidi, Suman; Martin, Alexandre

    2017-01-01

    Due to the complex physics encountered during reentry, material response solvers are used for two main purposes: improve the understanding of the physical phenomena; and design and size thermal protection systems (TPS). Icarus, is a three dimensional, unstructured material response tool that is intended to be used for design while maintaining the flexibility to easily implement physical models as needed. Because TPS selection and sizing is critical, it is of the utmost importance that the design tools be extensively verified and validated before their use. Verification tests aim at insuring that the numerical schemes and equations are implemented correctly by comparison to analytical solutions and grid convergence tests.

  7. Engaging Students in Physical Education: Key Challenges and Opportunities for Physical Educators in Urban Settings

    ERIC Educational Resources Information Center

    Sliwa, Sarah; Nihiser, Allison; Lee, Sarah; McCaughtry, Nathan; Culp, Brian; Michael, Shannon

    2017-01-01

    In October 2009, "JOPERD" published a special issue about "Engaging Urban Youths in Physical Education and Physical Activity." Seven years later, many of the considerations mentioned remain relevant, such as large class sizes, limited access to equipment, and the lack of a dedicated gymnasium or outdoor space. These structural…

  8. Pre-Service Physics Teachers' Ideas on Size, Visibility and Structure of the Atom

    ERIC Educational Resources Information Center

    Unlu, Pervin

    2010-01-01

    Understanding the atom gives the opportunity to both understand and conceptually unify the various domains of science, such as physics, chemistry, biology, astronomy and geology. Among these disciplines, physics teachers are expected to be particularly well educated in this topic. It is important that pre-service physics teachers know what sort of…

  9. Determination of calibration parameters of a VRX CT system using an “Amoeba” algorithm

    PubMed Central

    Jordan, Lawrence M.; DiBianca, Frank A.; Melnyk, Roman; Choudhary, Apoorva; Shukla, Hemant; Laughter, Joseph; Gaber, M. Waleed

    2008-01-01

    Efforts to improve the spatial resolution of CT scanners have focused mainly on reducing the source and detector element sizes, ignoring losses from the size of the secondary-ionization charge “clouds” created by the detected x-ray photons, i.e., the “physics limit.” This paper focuses on implementing a technique called “projective compression.” which allows further reduction in effective cell size while overcoming the physics limit as well. Projective compression signifies detector geometries in which the apparent cell size is smaller than the physical cell size, allowing large resolution boosts. A realization of this technique has been developed with a dual-arm “variable-resolution x-ray” (VRX) detector. Accurate values of the geometrical parameters are needed to convert VRX outputs to formats ready for optimal image reconstruction by standard CT techniques. The required calibrating data are obtained by scanning a rotating pin and fitting a theoretical parametric curve (using a multi-parameter minimization algorithm) to the resulting pin sinogram. Excellent fits are obtained for both detector-arm sections with an average (maximum) fit deviation of ~0.05 (0.1) detector cell width. Fit convergence and sensitivity to starting conditions are considered. Pre- and post-optimization reconstructions of the alignment pin and a biological subject reconstruction after calibration are shown. PMID:19430581

  10. Determination of calibration parameters of a VRX CT system using an "Amoeba" algorithm.

    PubMed

    Jordan, Lawrence M; Dibianca, Frank A; Melnyk, Roman; Choudhary, Apoorva; Shukla, Hemant; Laughter, Joseph; Gaber, M Waleed

    2004-01-01

    Efforts to improve the spatial resolution of CT scanners have focused mainly on reducing the source and detector element sizes, ignoring losses from the size of the secondary-ionization charge "clouds" created by the detected x-ray photons, i.e., the "physics limit." This paper focuses on implementing a technique called "projective compression." which allows further reduction in effective cell size while overcoming the physics limit as well. Projective compression signifies detector geometries in which the apparent cell size is smaller than the physical cell size, allowing large resolution boosts. A realization of this technique has been developed with a dual-arm "variable-resolution x-ray" (VRX) detector. Accurate values of the geometrical parameters are needed to convert VRX outputs to formats ready for optimal image reconstruction by standard CT techniques. The required calibrating data are obtained by scanning a rotating pin and fitting a theoretical parametric curve (using a multi-parameter minimization algorithm) to the resulting pin sinogram. Excellent fits are obtained for both detector-arm sections with an average (maximum) fit deviation of ~0.05 (0.1) detector cell width. Fit convergence and sensitivity to starting conditions are considered. Pre- and post-optimization reconstructions of the alignment pin and a biological subject reconstruction after calibration are shown.

  11. A Modeling Framework for Predicting the Size of Sediments Produced on Hillslopes and Supplied to Channels

    NASA Astrophysics Data System (ADS)

    Sklar, L. S.; Mahmoudi, M.

    2016-12-01

    Landscape evolution models rarely represent sediment size explicitly, despite the importance of sediment size in regulating rates of bedload sediment transport, river incision into bedrock, and many other processes in channels and on hillslopes. A key limitation has been the lack of a general model for predicting the size of sediments produced on hillslopes and supplied to channels. Here we present a framework for such a model, as a first step toward building a `geomorphic transport law' that balances mechanistic realism with computational simplicity and is widely applicable across diverse landscapes. The goal is to take as inputs landscape-scale boundary conditions such as lithology, climate and tectonics, and predict the spatial variation in the size distribution of sediments supplied to channels across catchments. The model framework has two components. The first predicts the initial size distribution of particles produced by erosion of bedrock underlying hillslopes, while the second accounts for the effects of physical and chemical weathering during transport down slopes and delivery to channels. The initial size distribution can be related to the spacing and orientation of fractures within bedrock, which depend on the stresses and deformation experienced during exhumation and on rock resistance to fracture propagation. Other controls on initial size include the sizes of mineral grains in crystalline rocks, the sizes of cemented particles in clastic sedimentary rocks, and the potential for characteristic size distributions produced by tree throw, frost cracking, and other erosional processes. To model how weathering processes transform the initial size distribution we consider the effects of erosion rate and the thickness of soil and weathered bedrock on hillslope residence time. Residence time determines the extent of size reduction, for given values of model terms that represent the potential for chemical and physical weathering. Chemical weathering potential is parameterized in terms of mean annual precipitation and temperature, and the fraction of soluble minerals. Physical weathering potential can be parameterized in terms of topographic attributes, including slope, curvature and aspect. Finally, we compare model predictions with field data from Inyo Creek in the Sierra Nevada Mtns, USA.

  12. The "Skinny" on Body Size Requests in Personal Ads.

    ERIC Educational Resources Information Center

    Miller, Erica J.; Smith, Jane Ellen; Trembath, David T.

    2000-01-01

    Surveyed personal ad writers to examine the actual preferences of those seeking thin partners, those seeking physically fit partners, or those with no preference. Respondents indicated ideal and acceptable partner body sizes. Males in the three categories differed significantly in choice of an ideal figure, though actual figure size differences…

  13. A Physics Finale.

    ERIC Educational Resources Information Center

    Haynes, Gail E.

    1991-01-01

    A third-semester physics course that covers the topics of atomic physics, the theory of relativity, and nuclear energy is described. Activities that include the phenomenon of radioactivity, field trips to a nuclear power plant, a simulation of a chain reaction, and comparing the size of atomic particles are presented. (KR)

  14. Changes in physical size among major league baseball players and its attribution to elite offensive performance.

    PubMed

    Crotin, Ryan L; Forsythe, Charles M; Bhan, Shivam; Karakolis, Thomas

    2014-10-01

    Major League Baseball (MLB) players have not been longitudinally examined for changes in physical size. Height, weight, and body mass indices (BMIs) were examined among offensive league leaders (OLL) and MLB reference cohorts at 1970, 1990, and 2010. Anthropometric values were expected to increase successively, where OLL were expected to be larger at each respective time point. A Mixed Model analysis of variance (p ≤ 0.05) examined anthropometric differences over time within and between groups. Mass and BMI increased over successive years with the largest effect seen between 1990 and 2010 (p < 0.001). A significant height reduction was shown for OLL from 1970 to 1990 (p ≤ 0.05), being the only significant decrease in physical size; yet, leaders were heavier and taller compared with the MLB reference population (p < 0.014). Results show that physical size has evolved in MLB, with the OLL being the largest players shown at each year in succession. Professional baseball scouts may have been influenced by greater offensive prowess shown by larger athletes; yet, increased secular anthropometrics must also be factored in greater heights, weights, BMIs shown over time in MLB. It is possible that greater participation in strength and conditioning programs at an earlier age, advances in sport nutrition, and potential abuse of anabolic drugs are factors perpetuating growth rates at present.

  15. Emulsified systems based on glyceryl monostearate and potassium cetyl phosphate: scale-up and characterization of physical properties.

    PubMed

    Baby, André Rolim; Santoro, Diego Monegatto; Velasco, Maria Valéria Robles; Dos Reis Serra, Cristina Helena

    2008-09-01

    Introducing a pharmaceutical product on the market involves several stages of research. The scale-up stage comprises the integration of previous phases of development and their integration. This phase is extremely important since many process limitations which do not appear on the small scale become significant on the transposition to a large one. Since scientific literature presents only a few reports about the characterization of emulsified systems involving their scaling-up, this research work aimed at evaluating physical properties of non-ionic and anionic emulsions during their manufacturing phases: laboratory stage and scale-up. Prototype non-ionic (glyceryl monostearate) and anionic (potassium cetyl phosphate) emulsified systems had the physical properties by the determination of the droplet size (D[4,3], mum) and rheology profile. Transposition occurred from a batch of 500-50,000g. Semi-industrial manufacturing involved distinct conditions: intensity of agitation and homogenization. Comparing the non-ionic and anionic systems, it was observed that anionic emulsifiers generated systems with smaller droplet size and higher viscosity in laboratory scale. Besides that, for the concentrations tested, augmentation of the glyceryl monostearate emulsifier content provided formulations with better physical characteristics. For systems with potassium cetyl phosphate, droplet size increased with the elevation of the emulsifier concentration, suggesting inadequate stability. The scale-up provoked more significant alterations on the rheological profile and droplet size on the anionic systems than the non-ionic.

  16. The feasibility of using explicit method for linear correction of the particle size variation using NIR Spectroscopy combined with PLS2regression method

    NASA Astrophysics Data System (ADS)

    Yulia, M.; Suhandy, D.

    2018-03-01

    NIR spectra obtained from spectral data acquisition system contains both chemical information of samples as well as physical information of the samples, such as particle size and bulk density. Several methods have been established for developing calibration models that can compensate for sample physical information variations. One common approach is to include physical information variation in the calibration model both explicitly and implicitly. The objective of this study was to evaluate the feasibility of using explicit method to compensate the influence of different particle size of coffee powder in NIR calibration model performance. A number of 220 coffee powder samples with two different types of coffee (civet and non-civet) and two different particle sizes (212 and 500 µm) were prepared. Spectral data was acquired using NIR spectrometer equipped with an integrating sphere for diffuse reflectance measurement. A discrimination method based on PLS-DA was conducted and the influence of different particle size on the performance of PLS-DA was investigated. In explicit method, we add directly the particle size as predicted variable results in an X block containing only the NIR spectra and a Y block containing the particle size and type of coffee. The explicit inclusion of the particle size into the calibration model is expected to improve the accuracy of type of coffee determination. The result shows that using explicit method the quality of the developed calibration model for type of coffee determination is a little bit superior with coefficient of determination (R2) = 0.99 and root mean square error of cross-validation (RMSECV) = 0.041. The performance of the PLS2 calibration model for type of coffee determination with particle size compensation was quite good and able to predict the type of coffee in two different particle sizes with relatively high R2 pred values. The prediction also resulted in low bias and RMSEP values.

  17. Measuring Physical Activity in Pregnancy Using Questionnaires: A Meta-Analysis

    PubMed

    Schuster, Snježana; Šklempe Kokić, Iva; Sindik, Joško

    2016-09-01

    Physical activity (PA) during normal pregnancy has various positive effects on pregnant women’s health. Determination of the relationship between PA and health outcomes requires accurate measurement of PA in pregnant women. The purpose of this review is to provide a summary of valid and reliable PA questionnaires for pregnant women. During 2013, Pubmed, OvidSP and Web of Science databases were searched for trials on measurement properties of PA questionnaires for pregnant population. Six studies and four questionnaires met the inclusion criteria: Pregnancy Physical Activity Questionnaire, Modified Kaiser Physical Activity Survey, Short Pregnancy Leisure Time Physical Activity Questionnaire and Third Pregnancy Infection and Nutrition Study Physical Activity Questionnaire. Assessment of validity and reliability was performed using correlations of the scores in these questionnaires with objective measures and subjective measures (self-report) of PA, as well as test-retest reliability coefficients. Sample sizes included in analysis varied from 45 to 177 subjects. The best validity and reliability characteristics (together with effect sizes) were identified for the Modified Kaiser Physical Activity Survey and Pregnancy Physical Activity Questionnaire (French, Vietnamese, standard). In conclusion, assessment of PA during pregnancy remains a challenging and complex task. Questionnaires are a simple and effective, yet limited tool for assessing PA.

  18. Effects of Distant Green Space on Physical Activity in Sydney, Australia.

    PubMed

    Chong, Shanley; Byun, Roy; Mazumdar, Soumya; Bauman, Adrian; Jalaludin, Bin

    2017-01-01

    The aim was to investigate the association between distant green space and physical activity modified by local green space. Information about physical activity, demographic and socioeconomic background at the individual level was extracted from the New South Wales Population Health Survey. The proportion of a postcode that was parkland was used as a proxy measure for access to parklands and was calculated for each individual. There was a significant relationship between distant green space and engaging in moderate-to-vigorous physical activity (MVPA) at least once a week. No significant relationship was found between adequate physical activity and distant green space. No significant relationships were found between adequate physical activity, engaging in MVPA, and local green space. However, if respondents lived in greater local green space (≥25%), there was a significant relationship between engaging in MVPA at least once a week and distance green space of ≥20%. This study highlights the important effect of distant green space on physical activity. Our findings also suggest that moderate size of local green space together with moderate size of distant green space are important levers for participation of physical activity.

  19. Effects of an integrated geriatric group balance class within an entry-level Doctorate of Physical Therapy program on students' perceptions of geriatrics and geriatric education in the United States.

    PubMed

    Reneker, Jennifer C; Weems, Kyra; Scaia, Vincent

    2016-01-01

    This study was aimed at determining the effect of an integrated group balance class for community-dwelling older adults within entry-level physical therapist coursework on student perceptions of geriatric physical therapy and geriatric physical therapy education. Twenty-nine Doctor of Physical Therapy (DPT) students, 21-33 years old, in their second year of coursework in 2012, participated in an integrated clinical experience with exposure to geriatric patients at an outpatient facility at the Louis Stokes Cleveland Department of Veterans Affairs Medical Center in Akron, Ohio, USA. Student perceptions were collected before and after participation in the 8-week balance class. The Wilcoxon sign-ranked test was used to identify differences in perceptions after participation in the group balance class. Cohen's d values were calculated to measure the size of the pre-participation to post-participation effect for each measure. At the conclusion of the group class, the DPT students demonstrated an increase in positive perceptions of geriatric physical therapy in 8 measures, with small effect sizes (d=0.15-0.30). Two perceptions of geriatric physical therapy demonstrated a significant positive increase (P<.05) with moderate effect sizes (d=0.47 and d=0.50). The students' perceptions of geriatric education in the curriculum demonstrated a large positive effect for quality (d=1.68) and enjoyment (d=1.96). Positive changes were found in most of the perceptions of geriatrics and geriatric education after participation, suggesting that integrated clinical experiences with geriatric patients are an effective way to positively influence perceptions of physical therapist practice with older adults.

  20. Estimating the Size of Onion Epidermal Cells from Diffraction Patterns

    ERIC Educational Resources Information Center

    Groff, Jeffrey R.

    2012-01-01

    Bioscience and premedical profession students are a major demographic served by introductory physics courses at many colleges and universities. Exposing these students to biological applications of physical principles will help them to appreciate physics as a useful tool for their future professions. Here I describe an experiment suitable for…

  1. Role of physical activity and sleep duration in growth and body composition of preschool-aged children

    USDA-ARS?s Scientific Manuscript database

    The impact of physical activity patterns and sleep duration on growth and body composition of preschool-aged children remains unresolved. Aims were (1) to delineate cross-sectional associations among physical activity components, sleep, total energy expenditure (TEE), and body size and composition; ...

  2. A GUIDE FOR PLANNING PHYSICAL EDUCATION AND ATHLETIC FACILITIES.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Education, Trenton.

    THIS STUDY EXAMINES PHYSICAL EDUCATION FACILITIES, THEIR PHYSICAL NEEDS, AND RELATED DESIGN CONSIDERATIONS. A SYSTEM OF DETERMINING THE TOTAL NUMBER OF TEACHING STATIONS NEEDED IS GIVEN TO AID INITIAL REQUIREMENT ANALYSIS. INDOOR FACILITIES ANALYZED INCLUDE--(1) THE GYMNASIUM, IN TERMS OF LOCATION, SIZE, DESIGN FEATURES, AND RELATED COMPONENTS,…

  3. Physical Attractiveness and Health in Western Societies: A Review

    ERIC Educational Resources Information Center

    Weeden, Jason; Sabini, John

    2005-01-01

    Evidence from developed Western societies is reviewed for the claims that (a) physical attractiveness judgments are substantially based on body size and shape, symmetry, sex-typical hormonal markers, and other specific cues and (b) physical attractiveness and these cues substantially predict health. Among the cues that the authors review, only…

  4. Infants use relative numerical group size to infer social dominance

    PubMed Central

    Pun, Anthea; Birch, Susan A. J.; Baron, Andrew Scott

    2016-01-01

    Detecting dominance relationships, within and across species, provides a clear fitness advantage because this ability helps individuals assess their potential risk of injury before engaging in a competition. Previous research has demonstrated that 10- to 13-mo-old infants can represent the dominance relationship between two agents in terms of their physical size (larger agent = more dominant), whereas younger infants fail to do so. It is unclear whether infants younger than 10 mo fail to represent dominance relationships in general, or whether they lack sensitivity to physical size as a cue to dominance. Two studies explored whether infants, like many species across the animal kingdom, use numerical group size to assess dominance relationships and whether this capacity emerges before their sensitivity to physical size. A third study ruled out an alternative explanation for our findings. Across these studies, we report that infants 6–12 mo of age use numerical group size to infer dominance relationships. Specifically, preverbal infants expect an agent from a numerically larger group to win in a right-of-way competition against an agent from a numerically smaller group. In addition, this is, to our knowledge, the first study to demonstrate that infants 6–9 mo of age are capable of understanding social dominance relations. These results demonstrate that infants’ understanding of social dominance relations may be based on evolutionarily relevant cues and reveal infants’ early sensitivity to an important adaptive function of social groups. PMID:26884199

  5. Choosing the Larger versus Choosing the Smaller: Asymmetries in the Size Congruity Effect

    ERIC Educational Resources Information Center

    Arend, Isabel; Henik, Avishai

    2015-01-01

    The size congruity effect (SiCE) shows that number and physical size interact as magnitudes. That is, response times are faster when number and size are congruent (e.g., 2 4) than when they are incongruent (e.g., 2 4). A shared representational system has been the most influential account for the SiCE. Recently, this account has been challenged by…

  6. The impact of compaction, moisture content, particle size and type of bulking agent on initial physical properties of sludge-bulking agent mixtures before composting.

    PubMed

    Huet, J; Druilhe, C; Trémier, A; Benoist, J C; Debenest, G

    2012-06-01

    This study aimed to experimentally acquire evolution profiles between depth, bulk density, Free Air Space (FAS), air permeability and thermal conductivity in initial composting materials. The impact of two different moisture content, two particle size and two types of bulking agent on these four parameters was also evaluated. Bulk density and thermal conductivity both increased with depth while FAS and air permeability both decreased with it. Moreover, depth and moisture content had a significant impact on almost all the four physical parameters contrary to particle size and the type of bulking agent. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Manually locating physical and virtual reality objects.

    PubMed

    Chen, Karen B; Kimmel, Ryan A; Bartholomew, Aaron; Ponto, Kevin; Gleicher, Michael L; Radwin, Robert G

    2014-09-01

    In this study, we compared how users locate physical and equivalent three-dimensional images of virtual objects in a cave automatic virtual environment (CAVE) using the hand to examine how human performance (accuracy, time, and approach) is affected by object size, location, and distance. Virtual reality (VR) offers the promise to flexibly simulate arbitrary environments for studying human performance. Previously, VR researchers primarily considered differences between virtual and physical distance estimation rather than reaching for close-up objects. Fourteen participants completed manual targeting tasks that involved reaching for corners on equivalent physical and virtual boxes of three different sizes. Predicted errors were calculated from a geometric model based on user interpupillary distance, eye location, distance from the eyes to the projector screen, and object. Users were 1.64 times less accurate (p < .001) and spent 1.49 times more time (p = .01) targeting virtual versus physical box corners using the hands. Predicted virtual targeting errors were on average 1.53 times (p < .05) greater than the observed errors for farther virtual targets but not significantly different for close-up virtual targets. Target size, location, and distance, in addition to binocular disparity, affected virtual object targeting inaccuracy. Observed virtual box inaccuracy was less than predicted for farther locations, suggesting possible influence of cues other than binocular vision. Human physical interaction with objects in VR for simulation, training, and prototyping involving reaching and manually handling virtual objects in a CAVE are more accurate than predicted when locating farther objects.

  8. Resource Security Impacts Men’s Female Breast Size Preferences

    PubMed Central

    Swami, Viren; Tovée, Martin J.

    2013-01-01

    It has been suggested human female breast size may act as signal of fat reserves, which in turn indicates access to resources. Based on this perspective, two studies were conducted to test the hypothesis that men experiencing relative resource insecurity should perceive larger breast size as more physically attractive than men experiencing resource security. In Study 1, 266 men from three sites in Malaysia varying in relative socioeconomic status (high to low) rated a series of animated figures varying in breast size for physical attractiveness. Results showed that men from the low socioeconomic context rated larger breasts as more attractive than did men from the medium socioeconomic context, who in turn perceived larger breasts as attractive than men from a high socioeconomic context. Study 2 compared the breast size judgements of 66 hungry versus 58 satiated men within the same environmental context in Britain. Results showed that hungry men rated larger breasts as significantly more attractive than satiated men. Taken together, these studies provide evidence that resource security impacts upon men’s attractiveness ratings based on women’s breast size. PMID:23483919

  9. Building the scholarly society infrastructure in physics in interwar America

    NASA Astrophysics Data System (ADS)

    Scheiding, Tom

    2013-11-01

    Starting in the interwar years both the quantity and quality of physics research conducted within the United States increased dramatically. To accommodate these increases there needed to be significant changes to the infrastructure within the scholarly society and particularly to the organization's ability to publish and distribute scholarly journals. Significant changes to the infrastructure in physics in the United States began with the formation of the American Institute of Physics as an umbrella organization for the major scholarly societies in American physics in 1931. The American Institute of Physics played a critical role in bringing about an expansion in the size of and breadth of coverage within scholarly journals in physics. The priority the American Institute of Physics placed on establishing a strong publication program and the creation of the American Institute of Physics itself were stimulated by extensive involvement and financial investments from the Chemical Foundation. It was journals of sufficient size and providing an appropriate level of coverage that were essential after World War II as physicists made use of increased patronage and public support to conduct even more research. The account offered here suggests that in important respects the significant government patronage that resulted from World War II accelerated changes that were already underway.

  10. Physical fitness and physical activity in fatigued and non-fatigued inflammatory bowel disease patients.

    PubMed

    Vogelaar, Lauran; van den Berg-Emons, Rita; Bussmann, Hans; Rozenberg, Robert; Timman, Reinier; van der Woude, Christien J

    2015-01-01

    To assess physical fitness and physical activity in inflammatory bowel disease (IBD) patients and whether fatigue is associated with impaired physical fitness and impaired physical activity. Ten patients with quiescent IBD and fatigue (fatigue group [FG]) based on the Checklist Individual Strength-Fatigue score of ≥35 were matched for age (±5 years) and sex with a non-fatigue group (NFG) with IBD. Physical fitness was measured with a cyclo-ergometric-based maximal exercise test, a submaximal 6-min walk test, and a dynamometer test to quantify the isokinetic muscle strength of the knee extensors and flexors. Level of physical activity was measured with an accelerometer-based activity monitor. The patients in both groups did not differ in regard to medication use, clinical characteristics, and body composition. However, medium-to-large effect sizes for impaired physical fitness (both cardiorespiratory fitness and muscle strength) and physical activity were seen between the patients in the FG and the NFG. Especially, intensity of physical activity was significantly lower in the FG patients compared with the NFG patients (effect size: 1.02; p = 0.037). Similar results were seen when outcomes of the FG and NFG were compared with reference values of the normal population. Fatigued IBD patients show an impaired physical fitness and physical activity compared with non-fatigued IBD patients. This gives directions for a physical component in fatigue in IBD patients. Therefore, these new insights into fatigue indicate that these patients might benefit from an exercise program to improve physical fitness and physical activity.

  11. NREL Senior Research Fellow Honored by The Journal of Physical Chemistry |

    Science.gov Websites

    and quantum size effects in semiconductors and carrier dynamics in semiconductor quantum dots and using hot carrier effects, size quantization, and superlattice concepts that could, in principle, enable

  12. Own Attractiveness and Dissatisfaction With Physical Appearance Independently Predict the Salience of Facial Cues to Size When Women Judge Other Women's Attractiveness.

    PubMed

    Watkins, Christopher D

    2017-11-01

    While facial cues to body size are a valid guide to health and attractiveness, it is unclear whether the observer's own condition predicts the salience of (low) size as a cue to female attractiveness. The current study examines whether measures related to women's own attractiveness/appearance predict the extent to which they use facial cues to size to differentiate other women on the attractiveness dimension. Women completed a body mass index (BMI) preference task, where they indicated their preference for high- versus low-BMI versions of the same woman, provided data to calculate their BMI and completed various psychometric measures (self-rated attractiveness/health, dissatisfaction with physical appearance). Here, attractive women and women who were dissatisfied with their own appearance were more likely to associate facial cues to low body size with high attractiveness. These data suggest that psychological factors related to women's appearance shape their evaluations of other women based on cues to size. Such variation in attractiveness judgements may function to reduce the costs of female competition for resources, for example, by identifying "quality" rivals or excluding others based on cues to size.

  13. Size-amplified acoustofluidic separation of circulating tumor cells with removable microbeads

    NASA Astrophysics Data System (ADS)

    Liu, Huiqin; Ao, Zheng; Cai, Bo; Shu, Xi; Chen, Keke; Rao, Lang; Luo, Changliang; Wang, Fu-Bin; Liu, Wei; Bondesson, Maria; Guo, Shishang; Guo, Feng

    2018-06-01

    Isolation and analysis of rare circulating tumor cells (CTCs) is of great interest in cancer diagnosis, prognosis, and treatment efficacy evaluation. Acoustofluidic cell separation becomes an attractive method due to its contactless, noninvasive, simple, and versatile features. However, the indistinctive physical difference between CTCs and normal blood cells limits the purity of CTCs using current acoustic methods. Herein, we demonstrate a size-amplified acoustic separation and release of CTCs with removable microbeads. CTCs selectively bound to size-amplifiers (40 μm-diameter anti-EpCAM/gelatin-coated SiO2 microbeads) have significant physical differences (size and mechanics) compared to normal blood cells, resulting in an amplification of acoustic radiation force approximately a hundredfold over that of bare CTCs or normal blood cells. Therefore, CTCs can be efficiently sorted out with size-amplifiers in a traveling surface acoustic wave microfluidic device and released from size-amplifiers by enzymatic degradation for further purification or downstream analysis. We demonstrate a cell separation from blood samples with a total efficiency (E total) of ∼ 77%, purity (P) of ∼ 96%, and viability (V) of ∼83% after releasing cells from size-amplifiers. Our method substantially improves the emerging application of rare cell purification for translational medicine.

  14. Racial bias in judgments of physical size and formidability: From size to threat.

    PubMed

    Wilson, John Paul; Hugenberg, Kurt; Rule, Nicholas O

    2017-07-01

    Black men tend to be stereotyped as threatening and, as a result, may be disproportionately targeted by police even when unarmed. Here, we found evidence that biased perceptions of young Black men's physical size may play a role in this process. The results of 7 studies showed that people have a bias to perceive young Black men as bigger (taller, heavier, more muscular) and more physically threatening (stronger, more capable of harm) than young White men. Both bottom-up cues of racial prototypicality and top-down information about race supported these misperceptions. Furthermore, this racial bias persisted even among a target sample from whom upper-body strength was controlled (suggesting that racial differences in formidability judgments are a product of bias rather than accuracy). Biased formidability judgments in turn promoted participants' justifications of hypothetical use of force against Black suspects of crime. Thus, perceivers appear to integrate multiple pieces of information to ultimately conclude that young Black men are more physically threatening than young White men, believing that they must therefore be controlled using more aggressive measures. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  15. Maximizing Information Diffusion in the Cyber-physical Integrated Network †

    PubMed Central

    Lu, Hongliang; Lv, Shaohe; Jiao, Xianlong; Wang, Xiaodong; Liu, Juan

    2015-01-01

    Nowadays, our living environment has been embedded with smart objects, such as smart sensors, smart watches and smart phones. They make cyberspace and physical space integrated by their abundant abilities of sensing, communication and computation, forming a cyber-physical integrated network. In order to maximize information diffusion in such a network, a group of objects are selected as the forwarding points. To optimize the selection, a minimum connected dominating set (CDS) strategy is adopted. However, existing approaches focus on minimizing the size of the CDS, neglecting an important factor: the weight of links. In this paper, we propose a distributed maximizing the probability of information diffusion (DMPID) algorithm in the cyber-physical integrated network. Unlike previous approaches that only consider the size of CDS selection, DMPID also considers the information spread probability that depends on the weight of links. To weaken the effects of excessively-weighted links, we also present an optimization strategy that can properly balance the two factors. The results of extensive simulation show that DMPID can nearly double the information diffusion probability, while keeping a reasonable size of selection with low overhead in different distributed networks. PMID:26569254

  16. Automated microfluidic platform for studies of carbon dioxide dissolution and solubility in physical solvents.

    PubMed

    Abolhasani, Milad; Singh, Mayank; Kumacheva, Eugenia; Günther, Axel

    2012-05-07

    We present an automated microfluidic (MF) approach for the systematic and rapid investigation of carbon dioxide (CO(2)) mass transfer and solubility in physical solvents. Uniformly sized bubbles of CO(2) with lengths exceeding the width of the microchannel (plugs) were isothermally generated in a co-flowing physical solvent within a gas-impermeable, silicon-based MF platform that is compatible with a wide range of solvents, temperatures and pressures. We dynamically determined the volume reduction of the plugs from images that were accommodated within a single field of view, six different downstream locations of the microchannel at any given flow condition. Evaluating plug sizes in real time allowed our automated strategy to suitably select inlet pressures and solvent flow rates such that otherwise dynamically self-selecting parameters (e.g., the plug size, the solvent segment size, and the plug velocity) could be either kept constant or systematically altered. Specifically, if a constant slug length was imposed, the volumetric dissolution rate of CO(2) could be deduced from the measured rate of plug shrinkage. The solubility of CO(2) in the physical solvent was obtained from a comparison between the terminal and the initial plug sizes. Solubility data were acquired every 5 min and were within 2-5% accuracy as compared to literature data. A parameter space consisting of the plug length, solvent slug length and plug velocity at the microchannel inlet was established for different CO(2)-solvent pairs with high and low gas solubilities. In a case study, we selected the gas-liquid pair CO(2)-dimethyl carbonate (DMC) and volumetric mass transfer coefficients 4-30 s(-1) (translating into mass transfer times between 0.25 s and 0.03 s), and Henry's constants, within the range of 6-12 MPa.

  17. Production of drug nanosuspensions: effect of drug physical properties on nanosizing efficiency.

    PubMed

    Liu, Tao; Müller, Rainer H; Möschwitzer, Jan P

    2018-02-01

    Drug nanosuspension is one of the established methods to improve the bioavailability of poorly soluble drugs. Drug physical properties aspect (morphology, solid state, starting size et al) is a critical parameter determining the production efficiency. Some drug modification approaches such as spray-drying were proved to improve the millability of drug powders. However, the mechanism behind those improved performances is unclear. This study is to systematically investigate the influence of those physical properties. Five different APIs (active pharmaceutical ingredients) with different millabilities, i.e. resveratrol, hesperetin, glibenclamide, rutin, and quercetin, were processed by standard high pressure homogenization (HPH), wet bead milling (WBM), and a combinative method of spray-drying and HPH. Smaller starting sizes of certain APIs could accelerate the particle size reduction velocity during both HPH and WBM processes. Spherical particles were observed for almost all spray-dried powders (except spray-dried hesperetin) after spray-drying. The crystallinity of some spray-dried samples such as rutin and glibenclamide became much lower than their corresponding unmodified powders. Almost all spray-dried drug powders after HPH processes could lead to smaller nanocrystal particle size than unmodified APIs. The modified microstructure instead of solid state after spray-drying explained the potential reason for improved nanosizing efficiency. In addition, the contribution of starting size on the production efficiency was also critical according to both HPH and WBM results.

  18. Color congruity effect: where do colors and numbers interact in synesthesia?

    PubMed

    Cohen Kadosh, Roi; Henik, Avishai

    2006-02-01

    The traditional size congruity paradigm is a Stroop-like situation where participants are asked to compare the values of two digits and ignore the irrelevant physical sizes of the digits (e.g., 3 5). Here a color congruity paradigm was employed and the irrelevant physical sizes were replaced by irrelevant colors. MM, a digit-color synesthete, yielded the classical congruity effect. Namely, she was slower to identify numerically larger numbers when they deviated from her synesthetic experience than when they matched it. In addition, the effect of color on her comparative judgments was modulated by numerical distance. In contrast, performance of non-synesthetes was not affected by the colors. On the basis of neurophysiological studies of magnitude comparison and interference between numerical and physical information, it is proposed that the interaction between colors and digits in MM occurs at the conceptual level. Moreover, by using the current paradigm it is possible to determine the stage at which color-digit binding in synesthesia occurs.

  19. Systematic Review of the Effects of Exercise on Activities of Daily Living in People With Alzheimer’s Disease

    PubMed Central

    Chou, Aileen; Bursley, Brett; Smulofsky, Jaclyn; Jezequel, Joel

    2014-01-01

    OBJECTIVE. Alzheimer’s disease (AD) results in a loss of independence in activities of daily living (ADLs), which in turn affects the quality of life of affected people and places a burden on caretakers. Limited research has examined the influence of physical training (aerobic, balance, and strength training) on ADL performance of people with AD. METHOD. Six randomized controlled trials (total of 446 participants) fit the inclusion criteria. For each study, we calculated effect sizes for primary and secondary outcomes. RESULTS. Average effect size (95% confidence interval) for exercise on the primary outcome (ADL performance) was 0.80 (p < .001). Exercise had a moderate impact on the secondary outcome of physical function (effect size = 0.53, p = .004). CONCLUSION. Occupational therapy intervention that includes aerobic and strengthening exercises may help improve independence in ADLs and improve physical performance in people with AD. Additional research is needed to identify specific components of intervention and optimal dosage to develop clinical guidelines. PMID:24367955

  20. [Interaction Between Occupational Vanadium Exposure and hsp70-hom on Neurobehavioral Function].

    PubMed

    Zhang, Qin; Liu, Yun-xing; Cui, Li; Li, Shun-pin; Gao, Wei; Hu, Gao-lin; Zhang, Zu-hui; Lan, Ya-jia

    2016-01-01

    In determine the effect of heat shock protein 70-hom gene (hsp70-hom) polymorphism on the neurobehavioral function of workers exposed to vanadium. Workers from the vanadium products and chemical industry were recruited by cluster sampling. Demographic data and exposure information were collected using a questionnaire. Neurobehavioral function was assessed by Neurobehavioral Core Test Battery. The hsp70-hom genotype was detected by restricted fragment length polymorphism-polymerase chain reaction (RFLP-PCR). A neurobehavioral index (NBI) was formulated through principal component analysis. Workers with a T/C genotype had worse performance in average reaction time, visual retention, digital span (backward), Santa Ana aiming (non-habitual hand), pursuit aiming (right points, total points), digit symbol and NBI score than others (P < 0.05). The relative risk of abnormal NBI score of the workers with a T/C genotype was 1.748 fold of those with a T/T genotype. The relative risk of abnormal.NBI score of the workers exposed to vanadium was 3.048 fold of controls (P < 0.05). But after adjustment with age and education, only vanadium exposure appeared with a significant effect on NBI score. When gene polymorphism and vanadium exposure coexisted, the effect of vanadium on neurobehavioral function was attenuated, but the influence of T/C genotype increased Codds ratio (OR = 4.577, P < 0.05). After adjustment with age and education, the OR of T/C genotype further increased to 7.777 (P < 0.05). Vanadium exposure and T/C genotype had.a bio-interaction effect on NBI score Crelative excess risk due to interaction (RERI) = 4.12, attributable proportion (AP) = 0.7, synergy index (S) = 6.45]. After adjustment with age and education, the RERI became 2.49 and the AP became 0.75, but no coefficient of interaction was produced. Priorities of occupational protection should be given to vanadium-exposed workers with a hsp70-hom T/C genotype and low education level.

  1. Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements.

    PubMed

    Antonijevic, Djordje; Jeschke, Anke; Colovic, Bozana; Milovanovic, Petar; Jevremovic, Danimir; Kisic, Danilo; vom Scheidt, Annika; Hahn, Michael; Amling, Michael; Jokanovic, Vukoman; Busse, Björn; Djuric, Marija

    2015-12-01

    Calcium silicate cements (CSCs) with the addition of nanohydroxyapatite and calcium carbonate play a critical role in dental applications. To further improve their properties, particularly radiopacity and biointeractivity, the fluoride-containing radiopacifier ytterbium trifluoride (YbF3) was added to their composition, and biological and mechanical characteristics were evaluated. YbF3 was added to 3 different CSCs: cement I (CSC + calcium carbonate), cement II (CSC + nanohydroxyapatite), and Portland cement. Material characterization encompassed measurements of pH, calcium, ytterbium, and fluoride ion release; radiopacity; setting time; porosity; microindentation properties; wettability; and Fourier transform infrared spectroscopic, x-ray diffraction, and scanning electron microscopic analyses. Osteoblast- and osteoclast-like cells were grown on the materials' surface to evaluate their adherence. The addition of calcium carbonate, nanohydroxyapatite, and 30 wt% of YbF3 improved radiopacity and the setting time of experimental cements. The pH values did not differ among the groups. The greatest ytterbium and fluoride releases occurred in the Portland cement + YbF3 group. Combined x-ray diffraction and Fourier transform infrared spectroscopic analysis showed the presence of calcium hydroxide and calcium silicate hydrates. In addition, the presence of calcium ytterbium fluoride and ytterbium oxide proved that YbF3 reacted with cement compounds. Wettability of cement I + YbF3 was superior to other formulations, but its porosity and microindentation properties were weaker than in the Portland cement + YbF3 mixture. Cement II + YbF3 presented micromechanical indentation and porosity characteristics similar to the Portland-based cement formulation. Osteoclast- and osteoblast-like cells adhered to the cements' surfaces without alteration of the cell structural integrity. YbF3-containing CSCs with nanostructured hydroxyapatite and calcium carbonate are well suited for dental application. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  2. Evaluation of a surface plasmon resonance imaging-based multiplex O-antigen serogrouping for Escherichia coli using eleven major serotypes of Shiga -toxin-producing E. coli.

    PubMed

    Nakano, Satoshi; Nagao, Miki; Yamasaki, Tomomi; Morimura, Hiroyuki; Hama, Natsuki; Iijima, Yoshio; Shinomiya, Hiroto; Tanaka, Michio; Yamamoto, Masaki; Matsumura, Yasufumi; Miyake, Shiro; Ichiyama, Satoshi

    2018-06-01

    The early detection of Shiga toxin-producing Escherichia coli (STEC) is important for early diagnosis and preventing the spread of STEC. Although the confirmatory test for STEC should be based on the detection of Shiga toxin using molecular analysis, isolation permits additional characterization of STEC using a variety of methods, including O:H serotyping. The conventional slide agglutination O-antigen serogrouping used in many clinical laboratories is laborious and time-consuming. Surface plasmon resonance (SPR)-based immunosensors are commonly used to investigate a large variety of bio-interactions such as antibody/antigen, peptide/antibody, DNA/DNA, and antibody/bacteria interactions. SPR imaging (SPRi) is characterized by multiplexing capabilities for rapidly screening (approximately 100 to several hundred sensorgrams in parallel) molecules. SPRi-based O-antigen serogrouping method for STEC was recently developed by detecting the interactions between O-antigen-specific antibodies and bacterial cells themselves. The aim of this study was to evaluate its performance for E. coli serogrouping using clinical STEC isolates by comparing the results of slide agglutination tests. We tested a total of 188 isolates, including O26, O45, O91, O103, O111, O115, O121, O128, O145, O157, and O159. The overall sensitivity of SPRi-based O-antigen serogrouping was 98.9%. Only two O157 isolates were misidentified as nontypeable and O121. The detection limits of all serotypes were distributed between 1.1 × 10 6 and 17.6 × 10 6  CFU/ml. Pulsed-field gel electrophoresis (PFGE) revealed the heterogeneity of the examined isolates. In conclusion, SPRi is a useful method for the O-antigen serogrouping of STEC isolates, but the further evaluation of non-O157 minor serogroups is needed. Copyright © 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  3. Habitability and the Multiverse

    NASA Astrophysics Data System (ADS)

    Sandora, M. E.

    2017-11-01

    Are the laws of physics set to maximize the habitability of the universe? We study how plate tectonics, core and mantle composition, homochirality, photosynthesis, and planet size depend on physics, and make predictions for where life will be found.

  4. The Bullied and Non-Bullied Child: A Contrast Between the Popular and Unpopular Child.

    ERIC Educational Resources Information Center

    Lowenstein, L. F.

    Characteristics of 32 children who claimed to be bullied were examined and compared to a control group. Teachers and a psychologist rated the Ss on three aspects: physical characteristics (size and weight for age, attractiveness, physical robustness, appropriateness of dress, odd mannerisms or physical handicaps); personal and psychological…

  5. Examining the Knowledge and Capacity of Elementary Teachers to Implement Classroom Physical Activity Breaks

    ERIC Educational Resources Information Center

    Dinkel, Danae M.; Lee, Jung-Min; Schaffer, Connie

    2016-01-01

    This study examined teachers' zone of proximal development for classroom physical activity breaks by assessing teachers' knowledge and capacity for implementing classroom physical activity breaks. Five school districts of various sizes (n = 346 teachers) took part in a short online survey. Descriptive statistics were calculated and chi-square…

  6. Short Term Motor-Skill Acquisition Improves with Size of Self-Controlled Virtual Hands

    PubMed Central

    Ossmy, Ori; Mukamel, Roy

    2017-01-01

    Visual feedback in general, and from the body in particular, is known to influence the performance of motor skills in humans. However, it is unclear how the acquisition of motor skills depends on specific visual feedback parameters such as the size of performing effector. Here, 21 healthy subjects physically trained to perform sequences of finger movements with their right hand. Through the use of 3D Virtual Reality devices, visual feedback during training consisted of virtual hands presented on the screen, tracking subject’s hand movements in real time. Importantly, the setup allowed us to manipulate the size of the displayed virtual hands across experimental conditions. We found that performance gains increase with the size of virtual hands. In contrast, when subjects trained by mere observation (i.e., in the absence of physical movement), manipulating the size of the virtual hand did not significantly affect subsequent performance gains. These results demonstrate that when it comes to short-term motor skill learning, the size of visual feedback matters. Furthermore, these results suggest that highest performance gains in individual subjects are achieved when the size of the virtual hand matches their real hand size. These results may have implications for optimizing motor training schemes. PMID:28056023

  7. Interpretations of family size distributions: The Datura example

    NASA Astrophysics Data System (ADS)

    Henych, Tomáš; Holsapple, Keith A.

    2018-04-01

    Young asteroid families are unique sources of information about fragmentation physics and the structure of their parent bodies, since their physical properties have not changed much since their birth. Families have different properties such as age, size, taxonomy, collision severity and others, and understanding the effect of those properties on our observations of the size-frequency distribution (SFD) of family fragments can give us important insights into the hypervelocity collision processes at scales we cannot achieve in our laboratories. Here we take as an example the very young Datura family, with a small 8-km parent body, and compare its size distribution to other families, with both large and small parent bodies, and created by both catastrophic and cratering formation events. We conclude that most likely explanation for the shallower size distribution compared to larger families is a more pronounced observational bias because of its small size. Its size distribution is perfectly normal when its parent body size is taken into account. We also discuss some other possibilities. In addition, we study another common feature: an offset or "bump" in the distribution occurring for a few of the larger elements. We hypothesize that it can be explained by a newly described regime of cratering, "spall cratering", which controls the majority of impact craters on the surface of small asteroids like Datura.

  8. Formation and size distribution of self-assembled vesicles

    PubMed Central

    Huang, Changjin; Quinn, David; Suresh, Subra

    2017-01-01

    When detergents and phospholipid membranes are dispersed in aqueous solutions, they tend to self-assemble into vesicles of various shapes and sizes by virtue of their hydrophobic and hydrophilic segments. A clearer understanding of such vesiculation processes holds promise for better elucidation of human physiology and disease, and paves the way to improved diagnostics, drug development, and drug delivery. Here we present a detailed analysis of the energetics and thermodynamics of vesiculation by recourse to nonlinear elasticity, taking into account large deformation that may arise during the vesiculation process. The effects of membrane size, spontaneous curvature, and membrane stiffness on vesiculation and vesicle size distribution were investigated, and the critical size for vesicle formation was determined and found to compare favorably with available experimental evidence. Our analysis also showed that the critical membrane size for spontaneous vesiculation was correlated with membrane thickness, and further illustrated how the combined effects of membrane thickness and physical properties influenced the size, shape, and distribution of vesicles. These findings shed light on the formation of physiological extracellular vesicles, such as exosomes. The findings also suggest pathways for manipulating the size, shape, distribution, and physical properties of synthetic vesicles, with potential applications in vesicle physiology, the pathobiology of cancer and other diseases, diagnostics using in vivo liquid biopsy, and drug delivery methods. PMID:28265065

  9. The Physical State of Emulsified Edible Oil Modulates Its in Vitro Digestion.

    PubMed

    Guo, Qing; Bellissimo, Nick; Rousseau, Dérick

    2017-10-18

    Emulsified lipid digestion was tailored by manipulating the physical state of dispersed oil droplets in whey protein stabilized oil-in-water (O/W) emulsions, where the oil phase consisted of one of five ratios of soybean oil (SO) and fully hydrogenated soybean oil (FHSO). The evolution in particle size distribution, structural changes during oral, gastric, and intestinal digestion, and free fatty acid release during intestinal digestion were all investigated. Irrespective of the physical state and structure of the dispersed oil/fat, all emulsions were stable against droplet size increases during oral digestion. During gastric digestion, the 50:50 SO:FHSO emulsion was more stable against physical breakdown than any other emulsion. All emulsions underwent flocculation and coalescence or partial coalescence upon intestinal digestion, with the SO emulsion being hydrolyzed the most rapidly. The melting point of all emulsions containing FHSO was above 37 °C, with the presence of solid fat within the dispersed oil droplets greatly limiting lipolysis. Fat crystal polymorph and nanoplatelet size did not play an important role in the rate and extent of lipid digestion. Free fatty acid release modeled by the Weibull distribution function showed that the rate of lipid digestion (κ) decreased with increasing solid fat content, and followed an exponential relationship (R 2 = 0.95). Overall, lipid digestion was heavily altered by the physical state of the dispersed oil phase within O/W emulsions.

  10. Diet- and body size-related attitudes and behaviors associated with vitamin supplement use in a representative sample of fourth-grade students in Texas.

    PubMed

    George, Goldy C; Hoelscher, Deanna M; Nicklas, Theresa A; Kelder, Steven H

    2009-01-01

    To examine diet- and body size-related attitudes and behaviors associated with supplement use in a representative sample of fourth-grade students in Texas. Cross-sectional data from the School Physical Activity and Nutrition study, a probability-based sample of schoolchildren. Children completed a questionnaire that assessed supplement use, food choices, diet-related attitudes, and physical activity; height and weight were measured. School classrooms. Representative sample of fourth-grade students in Texas (n = 5967; mean age = 9.7 years standard error of the mean [SEM] = .03 years, 46% Hispanic, 11% African-American). Previous day vitamin supplement consumption, diet- and body size-related attitudes, food choices, demographic factors, and physical activity. Multivariable logistic regression models, P < .05. The prevalence of supplement use was 29%. Supplement intake was associated with physical activity. Girls who used supplements were more likely to report positive body image and greater interest in trying new food. Relative to nonusers, supplement users were less likely to perceive that they always ate healthful food, although supplement use was associated with more healthful food choices in boys and girls (P < .001). The widespread use of supplements and clustering of supplement use with healthful diet and greater physical activity in fourth graders suggest that supplement use be closely investigated in studies of diet-disease precursor relations and lifestyle factors in children.

  11. Novel analytical methods to assess the chemical and physical properties of liposomes.

    PubMed

    Kothalawala, Nuwan; Mudalige, Thilak K; Sisco, Patrick; Linder, Sean W

    2018-08-01

    Liposomes are used in commercial pharmaceutical formulations (PFs) and dietary supplements (DSs) as a carrier vehicle to protect the active ingredient from degradation and to increase the half-life of the injectable. Even as the commercialization of liposomal products has rapidly increased, characterization methodologies to evaluate physical and chemical properties of the liposomal products have not been well-established. Herein we develop rapid methodologies to evaluate chemical and selected physical properties of liposomal formulations. Chemical properties of liposomes are determined by their lipid composition. The lipid composition is evaluated by first screening of the lipids present in the sample using HPLC-ELSD followed by HPLC-MSMS analysis with high mass accuracy (<5 ppm), fragmentation pattern and lipid structure databases searching. Physical properties such as particle size and size distribution were investigated using Tunable Resistive Pulse Sensing (TRPS). The developed methods were used to analyze commercially available PFs and DSs. As results, PFs contain distinct number of lipids as indicated by the manufacture, but DSs were more complicated containing a large number of lipids belonging to different sub-classes. Commercially available liposomes have particles with wide size distribution based on size measurements performed by TRPS. The high mass accuracy as well as identification lipids using multiple fragment ions aided to accurately identify the lipids and differentiate them from other lipophilic molecules. The developed analytical methodologies were successfully adapted to measure the physiochemical properties of commercial liposomes. Copyright © 2018. Published by Elsevier B.V.

  12. Physical and microbiological stability of an extemporaneous tacrolimus suspension for paediatric use.

    PubMed

    Han, J; Beeton, A; Long, P F; Wong, I; Tuleu, C

    2006-04-01

    An extemporaneous suspension of tacrolimus for paediatric use has recently been developed but poor bioavailability and erratic plasma concentrations were observed during clinical use. It was not clear whether this was due to changes in the physical properties of the suspension during storage. The aim of this work was to investigate the physical and microbiological stability over the recommended 8-week shelf-life of this extemporaneous tacrolimus suspension. Suspensions (0.5 mg/mL) were custom made by a special manufacturer under Good Manufacturing Practice conditions. The procedure involved mixing tacrolimus capsule contents into Ora Plus and Simple Syrup (1 : 1) using a mortar and pestle followed by an homogenization step. The particle sizes of the suspensions were measured using a MasterSizer. A light microscope equipped with polarizers was used to visualize any particle size changes or crystal growth. Viable bacterial and fungal contamination was assessed using standard colony count techniques on solid media. The suspensions were kept at 22-26 degrees C and evaluated weekly. The volume mean diameter d((4,3)) from laser diffraction did not change significantly. Light microscopy did not reveal any significant change in particle size or crystal growth. Contamination by viable and culturable micro-organisms could not be detected. The suspension was physically (particle size) and microbiologically stable during the 8-week study period suggesting other factors including poor dosing could be responsible for the pharmacokinetic variation observed during clinical use which warrants further investigation.

  13. Spatial characterization of Bessel-like beams for strong-field physics.

    PubMed

    Summers, Adam M; Yu, Xiaoming; Wang, Xinya; Raoul, Maxime; Nelson, Josh; Todd, Daniel; Zigo, Stefan; Lei, Shuting; Trallero-Herrero, Carlos A

    2017-02-06

    We present a compact, simple design for the generation and tuning of both the spot size and effective focal length of Bessel-like beams. In particular, this setup provides an important tool for the use of Bessel-like beams with high-power, femtosecond laser systems. Using a shallow angle axicon in conjunction with a spherical lens, we show that it is possible to focus Bessel-like modes to comparable focal spot sizes to sharp axicons while maintaining a long effective focal length. The resulting focal profiles are characterized in detail using an accurate high dynamic range imaging technique. Quantitatively, we introduce a metric (R0.8) which defines the spot-size containing 80% of the total energy. Our setup overcomes the typical compromise between long working distances and small spot sizes. This is particularly relevant for strong-field physics where most experiments must operate in vacuum.

  14. Influence of system size on the properties of a fluid adsorbed in a nanopore: Physical manifestations and methodological consequences

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Puibasset, Joël, E-mail: puibasset@cnrs-orleans.fr; Kierlik, Edouard, E-mail: edouard.kierlik@upmc.fr; Tarjus, Gilles, E-mail: tarjus@lptl.jussieu.fr

    Hysteresis and discontinuities in the isotherms of a fluid adsorbed in a nanopore in general hamper the determination of equilibrium thermodynamic properties, even in computer simulations. A way around this has been to consider both a reservoir of small size and a pore of small extent in order to restrict the fluctuations of density and approach a classical van der Waals loop. We assess this suggestion by thoroughly studying through Monte Carlo simulations and density functional theory the influence of system size on the equilibrium configurations of the adsorbed fluid and on the resulting isotherms. We stress the importance ofmore » pore-symmetry-breaking states that even for modest pore sizes lead to discontinuous isotherms and we discuss the physical relevance of these states and the methodological consequences for computing thermodynamic quantities.« less

  15. Association of Physical Activity and Sedentary Behavior With Psychological Well-Being Among Japanese Children: A Two-Year Longitudinal Study.

    PubMed

    Ishii, Kaori; Shibata, Ai; Adachi, Minoru; Oka, Koichiro

    2016-10-01

    Data on the effect of increased or decreased physical activity on children's psychological status are scarce, and effect sizes are small. This study conducted two-year longitudinal research to identify associations between physical activity, sedentary behavior, and psychological well-being in Japanese school children through a mail survey completed by 292 children aged 6-12 years. Data on sociodemographics, physical activity, sedentary behavior on weekdays and the weekend, and psychometrics (self-efficacy, anxiety, and behavioral/emotional problems) were collected using a self-reported questionnaire. A logistic regression analysis was performed, calculating odds ratios for physical activity, psychometrics, and baseline age and physical activity and sedentary behavior changes. For boys, a negative association was found between increased physical activity outside school and maintained or improved self-efficacy as opposed to a positive association in girls. Increased sedentary behavior on weekdays and long periods of sedentary behavior on weekends were associated with maintained or improved behavioral/emotional problems in girls only. This two-year longitudinal study is the first of its kind conducted in Japan. Although effect sizes were small, these results may nevertheless assist in intervention development to promote psychological well-being. © The Author(s) 2016.

  16. Kidney transplantation: a systematic review of interventional and observational studies of physical activity on intermediate outcomes.

    PubMed

    Macdonald, Jamie Hugo; Kirkman, Danielle; Jibani, Mahdi

    2009-11-01

    Kidney transplant patients have decreased quality and longevity of life. Whether exercise can positively affect associated outcomes such as physical functioning, metabolic syndrome, kidney function, and immune function, has only been addressed in relatively small studies. Thus the aim of this systematic review was to determine effects of physical activity level on these intermediate outcomes in kidney transplant patients. We electronically and hand searched to identify 21 studies (6 retrospective assessments of habitual physical activity and 15 intervention studies including 6 controlled trials). After study quality assessment, intermediate outcomes associated with quality and longevity of life were expressed as correlations or percentage changes in addition to effect sizes. Habitual physical activity level was positively associated with quality of life and aerobic fitness and negatively associated with body fat (medium to large effect sizes). Exercise interventions also showed medium to large positive effects on aerobic capacity (10%-114% increase) and muscle strength (10%-22% increase). However, exercise programs had minimal or contradictory effects on metabolic syndrome and immune and kidney function. In kidney transplant patients, physical activity intervention is warranted to enhance physical functioning. Whether exercise impacts on outcomes associated with longevity of life requires further study.

  17. Sediment Grain Size Measurements: Is There a Differenc Between Digested and Un-digested Samples? And Does the Organic Carbon of the Sample Play a Role

    EPA Science Inventory

    Grain size is a physical measurement commonly made in the analysis of many benthic systems. Grain size influences benthic community composition, can influence contaminant loading and can indicate the energy regime of a system. We have recently investigated the relationship betw...

  18. Evolution of egg target size: an analysis of selection on correlated characters.

    PubMed

    Podolsky, R D

    2001-12-01

    In broadcast-spawning marine organisms, chronic sperm limitation should select for traits that improve chances of sperm-egg contact. One mechanism may involve increasing the size of the physical or chemical target for sperm. However, models of fertilization kinetics predict that increasing egg size can reduce net zygote production due to an associated decline in fecundity. An alternate method for increasing physical target size is through addition of energetically inexpensive external structures, such as the jelly coats typical of eggs in species from several phyla. In selection experiments on eggs of the echinoid Dendraster excentricus, in which sperm was used as the agent of selection, eggs with larger overall targets were favored in fertilization. Actual shifts in target size following selection matched quantitative predictions of a model that assumed fertilization was proportional to target size. Jelly volume and ovum volume, two characters that contribute to target size, were correlated both within and among females. A cross-sectional analysis of selection partitioned the independent effects of these characters on fertilization success and showed that they experience similar direct selection pressures. Coupled with data on relative organic costs of the two materials, these results suggest that, under conditions where fertilization is limited by egg target size, selection should favor investment in low-cost accessory structures and may have a relatively weak effect on the evolution of ovum size.

  19. Survivability in Layered Networks

    DTIC Science & Technology

    2011-02-01

    of different lightpath routing formulations. ..... 60 2-7 Probabilty that logical topology becomes disconnected if physical links fail independently...13 14 15 Logical Topology Size Figure 2-7: Probabilty that logical topology becomes disconnected if physical links fail independently with probability

  20. [The evaluation of physical development of students].

    PubMed

    2012-01-01

    The article demonstrates that physical health of university students is conditioned by the aggregate of morpho-functional indices and depends on the development of physical qualities of students. The evaluation of mass/height indicators of female students demonstrates the increase of total body size and weakness of body build. The testing of physical readiness testified the ambiguity of high-speed and high-speed/power qualities and results of stamina evaluation.

  1. Models of Individual Dietary Behavior Based on Smartphone Data: The Influence of Routine, Physical Activity, Emotion, and Food Environment.

    PubMed

    Seto, Edmund; Hua, Jenna; Wu, Lemuel; Shia, Victor; Eom, Sue; Wang, May; Li, Yan

    2016-01-01

    Smartphone applications (apps) facilitate the collection of data on multiple aspects of behavior that are useful for characterizing baseline patterns and for monitoring progress in interventions aimed at promoting healthier lifestyles. Individual-based models can be used to examine whether behavior, such as diet, corresponds to certain typological patterns. The objectives of this paper are to demonstrate individual-based modeling methods relevant to a person's eating behavior, and the value of such approach compared to typical regression models. Using a mobile app, 2 weeks of physical activity and ecological momentary assessment (EMA) data, and 6 days of diet data were collected from 12 university students recruited from a university in Kunming, a rapidly developing city in southwest China. Phone GPS data were collected for the entire 2-week period, from which exposure to various food environments along each subject's activity space was determined. Physical activity was measured using phone accelerometry. Mobile phone EMA was used to assess self-reported emotion/feelings. The portion size of meals and food groups was determined from voice-annotated videos of meals. Individual-based regression models were used to characterize subjects as following one of 4 diet typologies: those with a routine portion sizes determined by time of day, those with portion sizes that balance physical activity (energy balance), those with portion sizes influenced by emotion, and those with portion sizes associated with food environments. Ample compliance with the phone-based behavioral assessment was observed for all participants. Across all individuals, 868 consumed food items were recorded, with fruits, grains and dairy foods dominating the portion sizes. On average, 218 hours of accelerometry and 35 EMA responses were recorded for each participant. For some subjects, the routine model was able to explain up to 47% of the variation in portion sizes, and the energy balance model was able to explain over 88% of the variation in portion sizes. Across all our subjects, the food environment was an important predictor of eating patterns. Generally, grouping all subjects into a pooled model performed worse than modeling each individual separately. A typological modeling approach was useful in understanding individual dietary behaviors in our cohort. This approach may be applicable to the study of other human behaviors, particularly those that collect repeated measures on individuals, and those involving smartphone-based behavioral measurement.

  2. "Every Child (of Every Size) Matters" in Physical Education! Physical Education's Role in Childhood Obesity

    ERIC Educational Resources Information Center

    Cale, Lorraine; Harris, Jo

    2013-01-01

    The role of schools and physical education in promoting health, producing a "healthy nation" and in tackling obesity has been increasingly recognised in recent years. In England this is evidenced by various policies, strategies and responses from government that have highlighted schools to be instrumental in addressing health broadly and…

  3. Bridging the Conceptual Gap between Free Fall and Drag-Dominated Regimes

    ERIC Educational Resources Information Center

    de Obaldia, Elida; Miller, Norma; Wittel, Fred; Jaimison, George; Wallis, Kendra

    2016-01-01

    Some misconceptions about physics are hard to change. For example, students continue to believe that heavier objects fall faster than light ones, even after a year of physics instruction. Physics misconceptions are persistent. Light objects do fall more slowly if their size-to-weight ratio is sufficient for drag to be appreciable. Motion through a…

  4. Effect of four different size reduction methods on the particle size, solubility enhancement and physical stability of nicergoline nanocrystals.

    PubMed

    Martena, Valentina; Shegokar, Ranjita; Di Martino, Piera; Müller, Rainer H

    2014-09-01

    Nicergoline, a poorly soluble active pharmaceutical ingredient, possesses vaso-active properties which causes peripheral and central vasodilatation. In this study, nanocrystals of nicergoline were prepared in an aqueous solution of polysorbate 80 (nanosuspension) by using four different laboratory scale size reduction techniques: high pressure homogenization (HPH), bead milling (BM) and combination techniques (high pressure homogenization followed by bead milling HPH + BM, and bead milling followed by high pressure homogenization BM + HPH). Nanocrystals were investigated regarding to their mean particles size, zeta potential and particle dissolution. A short term physical stability study on nanocrystals stored at three different temperatures (4, 20 and 40 °C) was performed to evaluate the tendency to change in particle size, aggregation and zeta potential. The size reduction technique and the process parameters like milling time, number of homogenization cycles and pressure greatly affected the size of nanocrystals. Among the techniques used, the combination techniques showed superior and consistent particle size reduction compared to the other two methods, HPH + BM and BM + HPH giving nanocrystals of a mean particle size of 260 and 353 nm, respectively. The particle dissolution was increased for any nanocrystals samples, but it was particularly increased by HPH and combination techniques. Independently to the production method, nicergoline nanocrystals showed slight increase in particle size over the time, but remained below 500 nm at 20 °C and refrigeration conditions.

  5. Spacecraft configuration study for second generation mobile satellite system

    NASA Technical Reports Server (NTRS)

    Louie, M.; Vonstentzsch, W.; Zanella, F.; Hayes, R.; Mcgovern, F.; Tyner, R.

    1985-01-01

    A high power, high performance communicatons satellite bus being developed is designed to satisfy a broad range of multimission payload requirements in a cost effective manner and is compatible with both STS and expendable launchers. Results are presented of tradeoff studies conducted to optimize the second generation mobile satellite system for its mass, power, and physical size. Investigations of the 20-meter antenna configuration, transponder linearization techniques, needed spacecraft modifications, and spacecraft power, dissipation, mass, and physical size indicate that the advanced spacecraft bus is capable of supporting the required payload for the satellite.

  6. Computing physical properties with quantum Monte Carlo methods with statistical fluctuations independent of system size.

    PubMed

    Assaraf, Roland

    2014-12-01

    We show that the recently proposed correlated sampling without reweighting procedure extends the locality (asymptotic independence of the system size) of a physical property to the statistical fluctuations of its estimator. This makes the approach potentially vastly more efficient for computing space-localized properties in large systems compared with standard correlated methods. A proof is given for a large collection of noninteracting fragments. Calculations on hydrogen chains suggest that this behavior holds not only for systems displaying short-range correlations, but also for systems with long-range correlations.

  7. Artificial Leaks in Container Closure Integrity Testing: Nonlinear Finite Element Simulation of Aperture Size Originated by a Copper Wire Sandwiched between the Stopper and the Glass Vial.

    PubMed

    Nieto, Alejandra; Roehl, Holger; Brown, Helen; Adler, Michael; Chalus, Pascal; Mahler, Hanns-Christian

    2016-01-01

    Container closure integrity (CCI) testing is required by different regulatory authorities in order to provide assurance of tightness of the container closure system against possible contamination, for example, by microorganisms. Microbial ingress CCI testing is performed by incubation of the container closure system with microorganisms under specified testing conditions. Physical CCI uses surrogate endpoints, such as coloration by dye solution ingress or gas flow (helium leakage testing). In order to correlate microbial CCI and physical CCI test methods and to evaluate the methods' capability to detect a given leak, artificial leaks are being introduced into the container closure system in a variety of different ways. In our study, artificial leaks were generated using inserted copper wires between the glass vial opening and rubber stopper. However, the insertion of copper wires introduces leaks of unknown size and shape. With nonlinear finite element simulations, the aperture size between the rubber stopper and the glass vial was calculated, depending on wire diameter and capping force. The dependency of the aperture size on the copper wire diameter was quadratic. With the data obtained, we were able to calculate the leak size and model leak shape. Our results suggest that the size as well as the shape of the artificial leaks should be taken into account when evaluating critical leak sizes, as flow rate does not, independently, correlate to hole size. Capping force also affected leak size. An increase in the capping force from 30 to 70 N resulted in a reduction of the aperture (leak size) by approximately 50% for all wire diameters. From 30 to 50 N, the reduction was approximately 33%. Container closure integrity (CCI) testing is required by different regulatory authorities in order to provide assurance of tightness of the container closure system against contamination, for example, by microorganisms. Microbial ingress CCI testing is performed by incubation of the container closure system with microorganisms under specified testing conditions. Physical CCI uses surrogate endpoints, such as coloration by dye solution ingress or gas flow. In order to correlate microbial ingress CCI and physical CCI test methods and to evaluate the methods' capability to detect a given leak, artificially created defects (artificial leaks) are being introduced into the container closure system in a variety of different ways. In our study, artificial leaks were generated using inserted copper wires between the glass vial opening and rubber stopper. Up to date, the insertion of copper wires introduced leaks of unknown size and shape. With nonlinear finite element simulations, the effective aperture size between the rubber stopper and the glass vial was calculated, depending on wire diameter and capping force, and the leak shape was modelled. Our results suggest that the size as well as the shape of the artificial leaks should be taken into account when evaluating critical leak sizes, as flow rate does not, independently, correlate to the hole size. © PDA, Inc. 2016.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hanthorn, H.E.; Jaech, J.L.

    Results are given of a study to determine the optimum testing scheme consisting of drawing a group of optimum size from the population being tested, and retesting it, if required, in subgroups of optimum size. An exact computation of optimum grouping and subgrouping was made. Results are also given to indicate how much loss inefficiency occurs when physical limitations restrict the size of the original group. (J.R.D.)

  9. Effects of varying particle size of forage on digestion and chewing behavior of dairy heifers.

    PubMed

    Jaster, E H; Murphy, M R

    1983-04-01

    Eighteen Holstein heifers were fed long and chopped coarse and fine alfalfa hay ad libitum to evaluate effects of physical form on digestion and chemical composition of feed and fecal particles and to examine the applicability of a sinusoidal model to chewing behavior. Recordings of jaw movement were divided into 1-h segments for analysis. Least square mean size of fecal particles from coarse and finely chopped diets were 290 and 297 micrometers as compared to 227 micrometers on long hay. Intakes of dry matter were greater an digestibilities lower for chopped as compared to long hay. Crude protein content of separated feed and fecal particles increased as particle size decreased. Neural and acid detergent fiber concentrations decreased in feed and feces with decreasing particle size. Lignin content of feed particles decreased as particle size decreased, whereas for fecal particles lignin as a percent of cell wall followed a "U" shaped pattern of declining then increasing as size decreased. Patterns were sinusoidal for eating and ruminating long and chopped hays and total chewing (eating and ruminating) of long hay. Our results suggest a gradual effect on chemical degradation and physical detrition of digesta particles and chewing behavior as forage particle size decreased.

  10. Size-dependent bending modulus of nanotubes induced by the imperfect boundary conditions

    PubMed Central

    Zhang, Jin

    2016-01-01

    The size-dependent bending modulus of nanotubes, which was widely observed in most existing three-point bending experiments [e.g., J. Phys. Chem. B 117, 4618–4625 (2013)], has been tacitly assumed to originate from the shear effect. In this paper, taking boron nitride nanotubes as an example, we directly measured the shear effect by molecular dynamics (MD) simulations and found that the shear effect is not the major factor responsible for the observed size-dependent bending modulus of nanotubes. To further explain the size-dependence phenomenon, we abandoned the assumption of perfect boundary conditions (BCs) utilized in the aforementioned experiments and studied the influence of the BCs on the bending modulus of nanotubes based on MD simulations. The results show that the imperfect BCs also make the bending modulus of nanotubes size-dependent. Moreover, the size-dependence phenomenon induced by the imperfect BCs is much more significant than that induced by the shear effect, which suggests that the imperfect BC is a possible physical origin that leads to the strong size-dependence of the bending modulus found in the aforementioned experiments. To capture the physics behind the MD simulation results, a beam model with the general BCs is proposed and found to fit the experimental data very well. PMID:27941866

  11. Response trajectories capture the continuous dynamics of the size congruity effect.

    PubMed

    Faulkenberry, Thomas J; Cruise, Alexander; Lavro, Dmitri; Shaki, Samuel

    2016-01-01

    In a comparison task involving numbers, the size congruity effect refers to the general finding that responses are usually faster when there is a match between numerical size and physical size (e.g., 2-8) than when there is a mismatch (e.g., 2-8). In the present study, we used computer mouse tracking to test two competing models of the size congruity effect: an early interaction model, where interference occurs at an early representational stage, and a late interaction model, where interference occurs as dynamic competition between response options. In three experiments, we found that the curvature of responses for incongruent trials was greater than for congruent trials. In Experiment 2 we showed that this curvature effect was reliably modulated by the numerical distance between the two stimulus numbers, with large distance pairs exhibiting a larger curvature effect than small distance pairs. In Experiment 3 we demonstrated that the congruity effects persist into response execution. These findings indicate that incongruities between numerical and physical sizes are carried throughout the response process and result from competition between parallel and partially active response options, lending further support to a late interaction model of the size congruity effect. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Built Environment Influences of Children's Physical Activity: Examining Differences by Neighbourhood Size and Sex.

    PubMed

    Mitchell, Christine A; Clark, Andrew F; Gilliland, Jason A

    2016-01-15

    Neighbourhoods can facilitate or constrain moderate-to-vigorous physical activity (MVPA) among children by providing or restricting opportunities for MVPA. However, there is no consensus on how to define a child's neighbourhood. This study examines the influence of the neighbourhood built environment on objectively measured MVPA among 435 children (aged 9-14 years) in London (ON, Canada). As there is no consensus on how to delineate a child's neighbourhood, a geographic information system was used to generate measures of the neighbourhood built environment at two buffer sizes (500 m and 800 m) around each child's home. Linear regression models with robust standard errors (cluster) were used to analyze the relationship between built environment characteristics and average daily MVPA during non-school hours on weekdays. Sex-stratified models assessed sex-specific relationships. When accounting for individual and neighbourhood socio-demographic variables, park space and multi-use path space were found to influence children's MVPA. Sex-stratified models found significant associations between MVPA and park space, with the 800 m buffer best explaining boys' MVPA and the 500 m buffer best explaining girls' MVPA. Findings emphasize that, when designing built environments, programs, and policies to facilitate physical activity, it is important to consider that the size of the neighbourhood influencing a child's physical activity may differ according to sex.

  13. Erosion and physical transport via overland flow of arsenic and lead bound to silt-sized particles

    PubMed Central

    Cadwalader, G. Owen; Renshaw, Carl E.; Jackson, Brian P.; Magilligan, Francis J.; Landis, Joshua D.; Bostick, Benjamin C.

    2011-01-01

    Understanding of the transport mechanisms of contaminated soils and sediment is essential for the sustainable management of contaminated lands. In New England and elsewhere, vast areas of agricultural lands are contaminated by the historical application of lead-arsenate pesticides. Left undisturbed the physical and chemical mobility of As and Pb in these soils is limited due to their strong affinity for adsorption onto solid phases. However, soil disturbance promotes erosion and overland flow during intense rainstorms. Here we investigate the event-scale transport of disturbed As and Pb contaminated soils through measurement of concentrations of As and Pb in suspended sediment and changes in Pb isotopic ratios in overland flow. Investigation of several rain events shows that where land disturbance has occurred, physical transport of silt-sized particles and aggregates is the primary transport vector of As and Pb derived from pesticide-contaminated soil. Although both As and Pb are associated with similarly-sized particles, we find that solid-phase As is more effectively mobilized and transported than Pb. Our results demonstrate that anthropogenic land disturbance of historical lands contaminated with lead-arsenate pesticides may redistribute, through physical transport, significant amounts of As, and lesser amounts of Pb, to riparian and stream sediments, where they are potentially more bioavailable. PMID:21552357

  14. Design and interpretation of anthropometric and fitness testing of basketball players.

    PubMed

    Drinkwater, Eric J; Pyne, David B; McKenna, Michael J

    2008-01-01

    The volume of literature on fitness testing in court sports such as basketball is considerably less than for field sports or individual sports such as running and cycling. Team sport performance is dependent upon a diverse range of qualities including size, fitness, sport-specific skills, team tactics, and psychological attributes. The game of basketball has evolved to have a high priority on body size and physical fitness by coaches and players. A player's size has a large influence on the position in the team, while the high-intensity, intermittent nature of the physical demands requires players to have a high level of fitness. Basketball coaches and sport scientists often use a battery of sport-specific physical tests to evaluate body size and composition, and aerobic fitness and power. This testing may be used to track changes within athletes over time to evaluate the effectiveness of training programmes or screen players for selection. Sports science research is establishing typical (or 'reference') values for both within-athlete changes and between-athlete differences. Newer statistical approaches such as magnitude-based inferences have emerged that are providing more meaningful interpretation of fitness testing results in the field for coaches and athletes. Careful selection and implementation of tests, and more pertinent interpretation of data, will enhance the value of fitness testing in high-level basketball programmes. This article presents reference values of fitness and body size in basketball players, and identifies practical methods of interpreting changes within players and differences between players beyond the null-hypothesis.

  15. The role of underestimating body size for self-esteem and self-efficacy among grade five children in Canada.

    PubMed

    Maximova, Katerina; Khan, Mohammad K A; Austin, S Bryn; Kirk, Sara F L; Veugelers, Paul J

    2015-10-01

    Underestimating body size hinders healthy behavior modification needed to prevent obesity. However, initiatives to improve body size misperceptions may have detrimental consequences on self-esteem and self-efficacy. Using sex-specific multiple mixed-effect logistic regression models, we examined the association of underestimating versus accurate body size perceptions with self-esteem and self-efficacy in a provincially representative sample of 5075 grade five school children. Body size perceptions were defined as the standardized difference between the body mass index (BMI, from measured height and weight) and self-perceived body size (Stunkard body rating scale). Self-esteem and self-efficacy for physical activity and healthy eating were self-reported. Most of overweight boys and girls (91% and 83%); and most of obese boys and girls (93% and 90%) underestimated body size. Underestimating weight was associated with greater self-efficacy for physical activity and healthy eating among normal-weight children (odds ratio: 1.9 and 1.6 for boys, 1.5 and 1.4 for girls) and greater self-esteem among overweight and obese children (odds ratio: 2.0 and 6.2 for boys, 2.0 and 3.4 for girls). Results highlight the importance of developing optimal intervention strategies as part of targeted obesity prevention efforts that de-emphasize the focus on body weight, while improving body size perceptions. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Modeling Physical Processes at the Nanoscale—Insight into Self-Organization of Small Systems (abstract)

    NASA Astrophysics Data System (ADS)

    Proykova, Ana

    2009-04-01

    Essential contributions have been made in the field of finite-size systems of ingredients interacting with potentials of various ranges. Theoretical simulations have revealed peculiar size effects on stability, ground state structure, phases, and phase transformation of systems confined in space and time. Models developed in the field of pure physics (atomic and molecular clusters) have been extended and successfully transferred to finite-size systems that seem very different—small-scale financial markets, autoimmune reactions, and social group reactions to advertisements. The models show that small-scale markets diverge unexpectedly fast as a result of small fluctuations; autoimmune reactions are sequences of two discontinuous phase transitions; and social groups possess critical behavior (social percolation) under the influence of an external field (advertisement). Some predicted size-dependent properties have been experimentally observed. These findings lead to the hypothesis that restrictions on an object's size determine the object's total internal (configuration) and external (environmental) interactions. Since phases are emergent phenomena produced by self-organization of a large number of particles, the occurrence of a phase in a system containing a small number of ingredients is remarkable.

  17. A measurement error model for physical activity level as measured by a questionnaire with application to the 1999-2006 NHANES questionnaire.

    PubMed

    Tooze, Janet A; Troiano, Richard P; Carroll, Raymond J; Moshfegh, Alanna J; Freedman, Laurence S

    2013-06-01

    Systematic investigations into the structure of measurement error of physical activity questionnaires are lacking. We propose a measurement error model for a physical activity questionnaire that uses physical activity level (the ratio of total energy expenditure to basal energy expenditure) to relate questionnaire-based reports of physical activity level to true physical activity levels. The 1999-2006 National Health and Nutrition Examination Survey physical activity questionnaire was administered to 433 participants aged 40-69 years in the Observing Protein and Energy Nutrition (OPEN) Study (Maryland, 1999-2000). Valid estimates of participants' total energy expenditure were also available from doubly labeled water, and basal energy expenditure was estimated from an equation; the ratio of those measures estimated true physical activity level ("truth"). We present a measurement error model that accommodates the mixture of errors that arise from assuming a classical measurement error model for doubly labeled water and a Berkson error model for the equation used to estimate basal energy expenditure. The method was then applied to the OPEN Study. Correlations between the questionnaire-based physical activity level and truth were modest (r = 0.32-0.41); attenuation factors (0.43-0.73) indicate that the use of questionnaire-based physical activity level would lead to attenuated estimates of effect size. Results suggest that sample sizes for estimating relationships between physical activity level and disease should be inflated, and that regression calibration can be used to provide measurement error-adjusted estimates of relationships between physical activity and disease.

  18. Relative value of physical examination, mammography, and breast sonography in evaluating the size of the primary tumor and regional lymph node metastases in women receiving neoadjuvant chemotherapy for locally advanced breast carcinoma.

    PubMed

    Herrada, J; Iyer, R B; Atkinson, E N; Sneige, N; Buzdar, A U; Hortobagyi, G N

    1997-09-01

    The purpose of this study was to correlate physical examination and sonographic and mammographic measurements of breast tumors and regional lymph nodes with pathological findings and to evaluate the effect of neoadjuvant chemotherapy on clinical Tumor-Node-Metastasis stage by noninvasive methods. This was a retrospective analysis of 100 patients with locally advanced breast cancer registered and treated in prospective trials of neoadjuvant chemotherapy. All patients received four cycles of a doxorubicin-containing regimen and had noninvasive evaluation of the primary tumor and regional lymph nodes before and after neoadjuvant chemotherapy by physical examination, sonography, and mammography and underwent breast surgery and axillary dissection within 5 weeks after completion of neoadjuvant chemotherapy. The correlations between clinical and pathological measurements were determined by Spearman rank correlation analysis. A proportional odds model was used to examine predictive values. Eighty-three patients had both a clinically detectable primary tumor and lymph node metastases. Sixty-four patients had a decrease in Tumor-Node-Metastasis stage after chemotherapy. For 54% of patients, there was concordance in clinical response between the primary tumor and lymph node compartment; for the rest, results were discordant. Physical examination correlated best with pathological findings in the measurement of the primary tumor (P = 0.0003), whereas sonography was the most accurate predictor of size for axillary lymph nodes (P = 0.0005). The combination of physical examination and mammography worked best for assessment of the primary tumor (P = 0.003), whereas combining physical examination with sonography gave optimal evaluation of regional lymph nodes (P = 0.0001). In conclusion, physical examination is the best noninvasive predictor of the real size of locally advanced primary breast cancer, whereas sonography correlates better with the real dimensions of axillary lymph nodes. The combination of physical examination with either mammography or sonography significantly improves the accuracy of noninvasive assessment of tumor dimensions.

  19. Inequalities in Sport and Physical Activity Programs in Ontario Schools.

    ERIC Educational Resources Information Center

    Macintosh, Donald

    1981-01-01

    Two recent studies of interschool sports and physical education in Ontario secondary schools examine the issues of differences in interschool sports participation as a reflection of socioeconomic background, gender of the participants, degree of participation, and school size.

  20. The relationship between media use and psychological and physical assets among third- to fifth-grade girls.

    PubMed

    Racine, Elizabeth F; DeBate, Rita D; Gabriel, Kelley P; High, Robin R

    2011-12-01

    Media use is associated with an increased risk of chronic disease and reduced quality of life among children. This study examined the relationship between media use during discretionary hours after school and psychological and physical assets among preadolescent girls. A cross-sectional analysis was conducted using data from a larger quasi-experimental evaluation of a positive youth development program through sport for third- to fifth-grade girls. Indicators of media use were the number of hours per school day spent watching television and videos and using computers. Psychological assets included global self-esteem, body size satisfaction, and commitment to physical activity; physical assets included physical activity. Nested random effects analysis of variance (ANOVA) models were used to examine the relationship between media use and psychological and physical assets controlling for relevant confounding factors. The analytic sample included 1027 participants; most were ≥10 years old, non-White; 27% self-reported ≥4 hours of media use on school days. In adjusted results, media use was inversely associated with self-esteem (p = .008) and commitment to physical activity (p < .001). Time spent using media was not associated with body size satisfaction or physical activity in this age group. Media use was negatively associated with self-esteem and commitment to physical activity. It may be useful for school professionals to encourage after-school programs that offer opportunities for girls to reduce sedentary pursuits and improve important psychological and physical assets. © 2011, American School Health Association.

  1. Maternal Leisure Time Physical Activity and Infant Birth Size.

    PubMed

    Badon, Sylvia E; Wander, Pandora L; Qiu, Chunfang; Miller, Raymond S; Williams, Michelle A; Enquobahrie, Daniel A

    2016-01-01

    Associations of maternal leisure time physical activity with birth size are inconsistent. Roles of infant sex and maternal prepregnancy body mass index (BMI) in these associations have not been studied. Participants (N = 3,310) in the Omega study, a cohort in Washington State (1996-2008), reported leisure time physical activity duration and energy expenditure in the year prepregnancy and in early pregnancy (mean 15 weeks gestation). Regression models estimated mean differences in infant head circumference, birthweight, and ponderal index (birthweight/length) across quartiles of pre- or early-pregnancy leisure time physical activity. We assessed effect modification by infant sex or prepregnancy overweight/obese status (BMI ≥ 25 kg/m). We observed positive associations between prepregnancy leisure time physical activity and head circumference overall and among male infants. Among males, each quartile increase in prepregnancy physical activity duration was associated with 0.14 cm (95% confidence interval = 0.046, 0.24; trend P = 0.004) greater head circumference. We did not observe associations between leisure time physical activity and birthweight or ponderal index overall. Each quartile increase in pre- or early-pregnancy physical activity duration was associated with 17-23 g lower birthweight among female infants and among women with normal prepregnancy BMI. We observed positive associations between prepregnancy leisure time physical activity and head circumference among male infants, and inverse associations of pre- and early-pregnancy physical activity with birthweight among female infants and women with normal prepregnancy BMI. Future studies should confirm results and elucidate mechanisms of observed associations.

  2. Neural correlates of the number–size interference task in children

    PubMed Central

    Kaufmann, Liane; Koppelstaetter, Florian; Siedentopf, Christian; Haala, Ilka; Haberlandt, Edda; Zimmerhackl, Lothar-Bernd; Felber, Stefan; Ischebeck, Anja

    2010-01-01

    In this functional magnetic resonance imaging study, 17 children were asked to make numerical and physical magnitude classifications while ignoring the other stimulus dimension (number–size interference task). Digit pairs were either incongruent (3 8) or neutral (3 8). Generally, numerical magnitude interferes with font size (congruity effect). Moreover, relative to numerically adjacent digits far ones yield quicker responses (distance effect). Behaviourally, robust distance and congruity effects were observed in both tasks. imaging baselline contrasts revealed activations in frontal, parietal, occipital and cerebellar areas bilaterally. Different from results usually reported for adultssmaller distances activated frontal, but not (intra-)parietal areas in children. Congruity effects became significant only in physical comparisons. Thus, even with comparable behavioural performance, cerebral activation patterns may differ substantially between children and adults. PMID:16603917

  3. Analytical Formulation for Sizing and Estimating the Dimensions and Weight of Wind Turbine Hub and Drivetrain Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guo, Y.; Parsons, T.; King, R.

    This report summarizes the theory, verification, and validation of a new sizing tool for wind turbine drivetrain components, the Drivetrain Systems Engineering (DriveSE) tool. DriveSE calculates the dimensions and mass properties of the hub, main shaft, main bearing(s), gearbox, bedplate, transformer if up-tower, and yaw system. The level of fi¬ delity for each component varies depending on whether semiempirical parametric or physics-based models are used. The physics-based models have internal iteration schemes based on system constraints and design criteria. Every model is validated against available industry data or finite-element analysis. The verification and validation results show that the models reasonablymore » capture primary drivers for the sizing and design of major drivetrain components.« less

  4. Association of the sense of coherence with physical and psychosocial health in the rehabilitation of osteoarthritis of the hip and knee: a prospective cohort study.

    PubMed

    Benz, Thomas; Angst, Felix; Lehmann, Susanne; Aeschlimann, André

    2013-05-04

    According to Antonovsky's salutogenic concept, a strong sense of coherence is associated with physical and psychological health. The goal of this study was to analyze the association of Antonovsky's sense of coherence with physical and psychosocial health components in patients with hip and knee osteoarthritis before and after in- and outpatient rehabilitation. Prospective cohort study with 335 patients, 136 (41%) with hip and 199 (59%) with knee osteoarthritis. The outcome was measured by Short Form-36 (SF-36), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Sense of Coherence (SOC-13). Baseline scores of the SF-36 and WOMAC scales and the observed effect sizes after rehabilitation were correlated with the baseline SOC-13. These correlations of the SF-36 scales were compared to the Factor Score Coefficients for the Mental Component Summary of SF-36, which quantify the factor load on the psychosocial dimension. Predictive impact of the baseline SOC-13 for the SF-36 and WOMAC scales (baseline scores and effect sizes) was then determined by multivariate linear regression controlled for possible confounders. At baseline, the SOC-13 correlated with the WOMAC scores between r = 0.18 (stiffness) and r = 0.25 (pain) and with the SF-36 scores between r = 0.10 (physical functioning) and r = 0.53 (mental health). The correlation of these SF-36 correlation coefficients to the Factor Score Coefficient of the SF-36 Mental Component Summary was r = 0.95. The correlations for the effect sizes (baseline → discharge) with the baseline SOC-13 global score were all negative and varied between r = 0.00 (physical functioning) and r = -0.19 (social functioning). In the multivariate linear regression model, the explained variance of the SF-36 scores by the baseline SOC-13 increased continuously from physical to psychosocial health dimensions (from 12.9% to 29.8%). This gradient was consistently observed for both the baseline scores and the effect sizes. The results of the WOMAC were consistent with the physical health scales of SF-36. The sense of coherence was associated with psychosocial health dimensions but hardly with physical health. The higher the load of a scale on the psychosocial dimension the higher was its correlation to the sense of coherence. This is in contrast to the idea of Antonovsky who predicted high associations with both mental and physical health.

  5. Associations between Anxiety, Self-Efficacy, and Outcomes by Gender and Body Size Dissatisfaction during Fitness in High School Physical Education

    ERIC Educational Resources Information Center

    Lodewyk, Ken R.; Sullivan, Philip

    2016-01-01

    Background: Noteworthy proportions of adolescents--particularly females--report negatively about their experiences regarding fitness and the testing of it during physical education (PE). These accounts often coincide with lower levels of body image, fitness, motivation, and physical activity and higher rates of attrition from optional PE. Purpose:…

  6. Effective fiber for lactating dairy cows: a physically adjusted NDF (paNDF) system

    USDA-ARS?s Scientific Manuscript database

    Multiplying dietary NDF by particle size (PS) has been used as an estimate of physically effective fiber (peNDF). Our objectives were to: 1) compare the use of peNDF as dietary NDF × PS vs. use of individual NDF and PS descriptors in a physically adjusted NDF (paNDF) system when used with other fact...

  7. How Much Space Does a Library Need? Justifying Collections Space in an Electronic Age

    ERIC Educational Resources Information Center

    Butkovich, Nancy J.

    2010-01-01

    In 2002, plans to merge Penn State's Physical Sciences Library and Mathematics Library provoked a controversy in the Eberly College of Science over the size of the library needed to support its departments. The College contended that a physical collection no more than 5 years old was adequate. A study of astronomy, chemistry, mathematics, physics,…

  8. Sizing up the threat: the envisioned physical formidability of terrorists tracks their leaders' failures and successes.

    PubMed

    Holbrook, Colin; Fessler, Daniel M T

    2013-04-01

    Victory in modern intergroup conflict derives from complex factors, including weaponry, economic resources, tactical outcomes, and leadership. We hypothesize that the mind summarizes such factors into simple metaphorical representations of physical size and strength, concrete dimensions that have determined the outcome of combat throughout both ontogenetic and phylogenetic experience. This model predicts that in the aftermath of tactical victories (e.g., killing an enemy leader), members of defeated groups will be conceptualized as less physically formidable. Conversely, reminders that groups possess effective leadership should lead their members to be envisioned as more physically formidable. Consonant with these predictions, in both an opportunistic study conducted immediately after Osama bin Laden's death was announced (Study 1) and a follow-up experiment conducted approximately a year later (Study 2), Americans for whom the killing was salient estimated a purported Islamic terrorist to be physically smaller/weaker. In Studies 3 and 4, primes of victorious terrorist leaders led to inflated estimates of terrorists' physical attributes. These findings elucidate how the mind represents contemporary military power, and may help to explain how even largely symbolic victories can influence reasoning about campaigns of coalitional aggression. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. A Cluster Randomized Controlled Trial on the Effects of Technology-aided Testing and Feedback on Physical Activity and Biological Age Among Employees in a Medium-sized Enterprise.

    PubMed

    Liukkonen, Mika; Nygård, Clas-Håkan; Laukkanen, Raija

    2017-12-01

    It has been suggested that engaging technology can empower individuals to be more proactive about their health and reduce their health risks. The aim of the present intervention was to study the effects of technology-aided testing and feedback on physical activity and biological age of employees in a middle-sized enterprise. In all, 121 employees (mean age 42 ± 10 years) participated in the 12-month three-arm cluster randomized trial. The fitness measurement process (Body Age) determined the participants' biological age in years. Physical activity was measured with the International Physical Activity Questionnaire Short Form. Physical activity did not change during the intervention. Biological age (better fitness) improved in all groups statistically significantly ( p  < 0.001), but with no interaction effects. The mean changes (years) in the groups were -2.20 for the controls, -2.83 for the group receiving their biological age and feedback, and -2.31 for the group receiving their biological age, feedback, and a training computer. Technology-aided testing with feedback does not seem to change the amount of physical activity but may enhance physical fitness measured by biological age.

  10. Versatile microrobotics using simple modular subunits

    NASA Astrophysics Data System (ADS)

    Cheang, U. Kei; Meshkati, Farshad; Kim, Hoyeon; Lee, Kyoungwoo; Fu, Henry Chien; Kim, Min Jun

    2016-07-01

    The realization of reconfigurable modular microrobots could aid drug delivery and microsurgery by allowing a single system to navigate diverse environments and perform multiple tasks. So far, microrobotic systems are limited by insufficient versatility; for instance, helical shapes commonly used for magnetic swimmers cannot effectively assemble and disassemble into different size and shapes. Here by using microswimmers with simple geometries constructed of spherical particles, we show how magnetohydrodynamics can be used to assemble and disassemble modular microrobots with different physical characteristics. We develop a mechanistic physical model that we use to improve assembly strategies. Furthermore, we experimentally demonstrate the feasibility of dynamically changing the physical properties of microswimmers through assembly and disassembly in a controlled fluidic environment. Finally, we show that different configurations have different swimming properties by examining swimming speed dependence on configuration size.

  11. Versatile microrobotics using simple modular subunits

    PubMed Central

    Cheang, U Kei; Meshkati, Farshad; Kim, Hoyeon; Lee, Kyoungwoo; Fu, Henry Chien; Kim, Min Jun

    2016-01-01

    The realization of reconfigurable modular microrobots could aid drug delivery and microsurgery by allowing a single system to navigate diverse environments and perform multiple tasks. So far, microrobotic systems are limited by insufficient versatility; for instance, helical shapes commonly used for magnetic swimmers cannot effectively assemble and disassemble into different size and shapes. Here by using microswimmers with simple geometries constructed of spherical particles, we show how magnetohydrodynamics can be used to assemble and disassemble modular microrobots with different physical characteristics. We develop a mechanistic physical model that we use to improve assembly strategies. Furthermore, we experimentally demonstrate the feasibility of dynamically changing the physical properties of microswimmers through assembly and disassembly in a controlled fluidic environment. Finally, we show that different configurations have different swimming properties by examining swimming speed dependence on configuration size. PMID:27464852

  12. Analysis of student engagement in an online annotation system in the context of a flipped introductory physics class

    NASA Astrophysics Data System (ADS)

    Miller, Kelly; Zyto, Sacha; Karger, David; Yoo, Junehee; Mazur, Eric

    2016-12-01

    We discuss student participation in an online social annotation forum over two semesters of a flipped, introductory physics course at Harvard University. We find that students who engage in high-level discussion online, especially by providing answers to their peers' questions, make more gains in conceptual understanding than students who do not. This is true regardless of students' physics background. We find that we can steer online interaction towards more productive and engaging discussion by seeding the discussion and managing the size of the sections. Seeded sections produce higher quality annotations and a greater proportion of generative threads than unseeded sections. Larger sections produce longer threads; however, beyond a certain section size, the quality of the discussion decreases.

  13. Systematic review of the effects of exercise on activities of daily living in people with Alzheimer's disease.

    PubMed

    Rao, Ashwini K; Chou, Aileen; Bursley, Brett; Smulofsky, Jaclyn; Jezequel, Joel

    2014-01-01

    OBJECTIVE. Alzheimer's disease (AD) results in a loss of independence in activities of daily living (ADLs), which in turn affects the quality of life of affected people and places a burden on caretakers. Limited research has examined the influence of physical training (aerobic, balance, and strength training) on ADL performance of people with AD. METHOD. Six randomized controlled trials (total of 446 participants) fit the inclusion criteria. For each study, we calculated effect sizes for primary and secondary outcomes. RESULTS. Average effect size (95% confidence interval) for exercise on the primary outcome (ADL performance) was 0.80 (p < .001). Exercise had a moderate impact on the secondary outcome of physical function (effect size = 0.53, p = .004). CONCLUSION. Occupational therapy intervention that includes aerobic and strengthening exercises may help improve independence in ADLs and improve physical performance in people with AD. Additional research is needed to identify specific components of intervention and optimal dosage to develop clinical guidelines. Copyright © 2014 by the American Occupational Therapy Association, Inc.

  14. Experimental modelling of fragmentation applied to volcanic explosions

    NASA Astrophysics Data System (ADS)

    Haug, Øystein Thordén; Galland, Olivier; Gisler, Galen R.

    2013-12-01

    Explosions during volcanic eruptions cause fragmentation of magma and host rock, resulting in fragments with sizes ranging from boulders to fine ash. The products can be described by fragment size distributions (FSD), which commonly follow power laws with exponent D. The processes that lead to power-law distributions and the physical parameters that control D remain unknown. We developed a quantitative experimental procedure to study the physics of the fragmentation process through time. The apparatus consists of a Hele-Shaw cell containing a layer of cohesive silica flour that is fragmented by a rapid injection of pressurized air. The evolving fragmentation of the flour is monitored with a high-speed camera, and the images are analysed to obtain the evolution of the number of fragments (N), their average size (A), and the FSD. Using the results from our image-analysis procedure, we find transient empirical laws for N, A and the exponent D of the power-law FSD as functions of the initial air pressure. We show that our experimental procedure is a promising tool for unravelling the complex physics of fragmentation during phreatomagmatic and phreatic eruptions.

  15. Fat is fashionable and fit: A comparative content analysis of Fatspiration and Health at Every Size® Instagram images.

    PubMed

    Webb, Jennifer B; Vinoski, Erin R; Bonar, Adrienne S; Davies, Alexandria E; Etzel, Lena

    2017-09-01

    In step with the proliferation of Thinspiration and Fitspiration content disseminated in popular web-based media, the fat acceptance movement has garnered heightened visibility within mainstream culture via the burgeoning Fatosphere weblog community. The present study extended previous Fatosphere research by comparing the shared and distinct strategies used to represent and motivate a fat-accepting lifestyle among 400 images sourced from Fatspiration- and Health at Every Size ® -themed hashtags on Instagram. Images were systematically analyzed for the socio-demographic and body size attributes of the individuals portrayed alongside content reflecting dimensions of general fat acceptance, physical appearance pride, physical activity and health, fat shaming, and eating and weight loss-related themes. #fatspiration/#fatspo-tagged images more frequently promoted fat acceptance through fashion and beauty-related activism; #healthateverysize/#haes posts more often featured physically-active portrayals, holistic well-being, and weight stigma. Findings provide insight into the common and unique motivational factors and contradictory messages encountered in these fat-accepting social media communities. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Solidification of liposomes by freeze-drying: the importance of incorporating gelatin as interior support on enhanced physical stability.

    PubMed

    Guan, Peipei; Lu, Yi; Qi, Jianping; Niu, Mengmeng; Lian, Ruyue; Wu, Wei

    2015-01-30

    The main purpose of this study was to investigate the effect of gelatin as interior support on the physical stability of freeze-dried liposomes. Anticancer agent paclitaxel (PTX) was selected as a model drug. Freeze-dried liposomes containing interior gelatin support (GLs) were prepared by thin-film dispersion/freeze-drying method. Several properties of the GLs, including entrapment efficiency, particle size and gelation temperature, were extensively characterized. Encapsulation efficiency of conventional liposomes (CLs) and liposomes containing lyoprotectants as interior support dropped to lower than 20% after reconstitution, while GLs still maintained an entrapment efficiency of over 84%. Scanning electron microscopy revealed well preserved liposomal structure of GLs after reconstitution. Meanwhile, the particle size and entrapment efficiency of GLs were also well preserved after reconstitution. In contrary, deformation of CLs and recrystallization of PTX were observed, as well as significant changes in particle size and entrapment efficiency. Taken together, interior gelatin support obviously enhanced the physical stability of liposomes against the lyophilization stress. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. [Influencing factors on HRQOL of physically disabled persons].

    PubMed

    Kim, Kye-Ha; Kim, Ok-Soo

    2005-06-01

    The purpose of this study was to investigate the influencing factors on health-related quality of life of physically disabled persons. Data was collected from 96 persons with a physical disability in three cities in Korea from June to September, 2003. Social support and depression were measured by a Social Support Questionnaire 6 (SSQ6) and Center for Epidemiologic Studies Depression questionnaire (CES-D). The Rosenberg Self-esteem Scale was used to measure self-esteem. Health-related quality of life (HRQOL) was measured using Smith Kline Beecham Quality of Life Scale (SBQOL). The SPSS WIN 11.0 version program was used for data analysis. There were significant differences of HRQOL according to monthly income and economic status. All subjects had a high level of depression and low self-esteem. The findings of this study show that self-esteem and the size of the social support network are significant influencing variables on HRQOL in physically disabled persons. Nursing intervention and counseling programs which improve self-esteem and increase the size of a social support network are needed to promote HRQOL in physically disabled persons.

  18. Determining The Provenance Of Sedimentary Materials On Mars Through Analog Studies

    NASA Astrophysics Data System (ADS)

    Craddock, R. A.

    2017-12-01

    The amount and types of sedimentary material available for transport can control the types of features that result from aeolian or fluvial processes. For example, if sediment availability increases dune forms transition from barchans to linear dunes. The availability of sediment and the erodibilty of the landscape can influence drainage divides, catchment areas, and stream type. There is abundant evidence of both aeolian and fluvial sediments on Mars with grain sizes ranging from silt/clay to pebbles and cobbles. However, what is unique about Mars is that the dominant rock type on the surface is basalt, and basalt does not typically weather into coarser particles sizes larger than silt/clay. So where does all the sand come from on Mars? Chemical weathering would produce clays. While mechanical weathering is possible, there are really only two end member processes: impact cratering and physical abrasion. Impact cratering can produce a wide range of particle sizes from house sized boulders to fine dust, but how much sand can be expected to be produced from impact craters? Physical abrasion is likely to be inefficient on Mars, resulting in the fast breakdown of sand-sized particles while producing more silt/clay sized particles. Other processes for generating sand on Mars include hyaloclastic, phreatomagmatic, and pyroclastic. These processes typically require the presence of water. This presentation will explore the possible diagnostic characteristics of sediments generated from these different processes. It will also show how basaltic sediments change as they are transported by water, wind, and ice. The image shows the physical characteristics of basaltic sediment transported by different geologic processes.

  19. Why Barbie Feels Heavier than Ken: The Influence of Size-Based Expectancies and Social Cues on the Illusory Perception of Weight

    ERIC Educational Resources Information Center

    Dijker, Anton J. M.

    2008-01-01

    In order to examine the relative influence of size-based expectancies and social cues on the perceived weight of objects, two studies were performed, using equally weighing dolls differing in sex-related and age-related vulnerability or physical strength cues. To increase variation in perceived size, stimulus objects were viewed through optical…

  20. Hydro-physical Characteristics of Selected Media Used for Containerized Agriculture Systems

    USDA-ARS?s Scientific Manuscript database

    Containerized plant production represents an extremely intensive agricultural practice with large amounts of water and fertilizer application. Hydro-physical characteristics such as water infiltration, texture and structure, particle size distribution affect the quality of the media used in containe...

  1. Diet Quality and Physical Activity Outcome Improvements Resulting From a Church-Based Diet and Supervised Physical Activity Intervention for Rural, Southern, African American Adults: Delta Body and Soul III.

    PubMed

    Thomson, Jessica L; Goodman, Melissa H; Tussing-Humphreys, Lisa

    2015-09-01

    We assessed the effects of a 6-month, church-based, diet and supervised physical activity intervention, conducted between 2011 and 2012, on improving diet quality and increasing physical activity of Southern, African American adults. Using a quasi-experimental design, eight self-selected, eligible churches were assigned to intervention or control. Assessments included dietary, physical activity, anthropometric, and clinical measures. Mixed model regression analysis and McNemar's test were used to determine if within and between group differences were significant. Cohen's d effect sizes for selected outcomes also were computed and compared with an earlier, lower dose intervention. Retention rates were 84% (102/122) for control and 76% (219/287) for intervention participants. Diet quality components, including fruits, vegetables, discretionary calories, and total quality, improved significantly in the intervention group. Strength/flexibility physical activity also increased in the intervention group, while both aerobic and strength/flexibility physical activity significantly decreased in the control group. Effect sizes for selected health outcomes were larger in the current intervention as compared to an earlier, less intense iteration of the study. Results suggest that more frequent education sessions as well as supervised group physical activity may be key components to increasing the efficacy of behavioral lifestyle interventions in rural, Southern, African American adults. © 2015 Society for Public Health Education.

  2. Adherence to Bergmann's rule by lizards may depend on thermoregulatory mode: support from a nocturnal gecko.

    PubMed

    Penniket, Sophie; Cree, Alison

    2015-06-01

    Bergmann's rule predicts an increase in body size with decreasing environmental temperature; however, the converse pattern has been found in the majority of lizards studied to date. For these ectotherms, small body size may provide thermal benefits (rapid heat uptake when basking), which would be highly advantageous in cold environments. Yet such an advantage may not exist in nocturnal lizards (which do not avidly bask), in which Bergmann's rule has not been closely studied. We have examined whether the body size of a primarily nocturnal gecko, Woodworthia "Otago/Southland" changed with elevation and operative temperature (determined using physical copper models). In a laboratory study, we investigated whether thermoregulatory mode (heliothermy or thigmothermy) alters the effect of body size on heating and cooling rates. This gecko followed Bergmann's rule, thereby showing the opposite of the dominant pattern in diurnal lizards. Size at maturity, maximum size of adults and size at birth were larger at higher elevations and at lower operative temperatures. Using physical models, we found that large body size can confer thermal benefits for nocturnal lizards that remain within diurnal retreats. Bergmann's rule should not be dismissed for all lizards. Our results clearly support Bergmann's rule for at least one thigmothermic species, for which large body size may provide thermal benefits. Future studies on Bergmann's rule in lizards should consider thermoregulatory mode. We advocate that this ecogeographic rule be examined in relation to operative temperature measured at field sites. Finally, we predict that climate warming may weaken the relationship between body size and elevation in this gecko.

  3. Role of physical bolus properties as sensory inputs in the trigger of swallowing.

    PubMed

    Peyron, Marie-Agnès; Gierczynski, Isabelle; Hartmann, Christoph; Loret, Chrystel; Dardevet, Dominique; Martin, Nathalie; Woda, Alain

    2011-01-01

    Swallowing is triggered when a food bolus being prepared by mastication has reached a defined state. However, although this view is consensual and well supported, the physical properties of the swallowable bolus have been under-researched. We tested the hypothesis that measuring bolus physical changes during the masticatory sequence to deglutition would reveal the bolus properties potentially involved in swallowing initiation. Twenty normo-dentate young adults were instructed to chew portions of cereal and spit out the boluses at different times in the masticatory sequence. The mechanical properties of the collected boluses were measured by a texture profile analysis test currently used in food science. The median particle size of the boluses was evaluated by sieving. In a simultaneous sensory study, twenty-five other subjects expressed their perception of bolus texture dominating at any mastication time. Several physical changes appeared in the food bolus as it was formed during mastication: (1) in rheological terms, bolus hardness rapidly decreased as the masticatory sequence progressed, (2) by contrast, adhesiveness, springiness and cohesiveness regularly increased until the time of swallowing, (3) median particle size, indicating the bolus particle size distribution, decreased mostly during the first third of the masticatory sequence, (4) except for hardness, the rheological changes still appeared in the boluses collected just before swallowing, and (5) physical changes occurred, with sensory stickiness being described by the subjects as a dominant perception of the bolus at the end of mastication. Although these physical and sensory changes progressed in the course of mastication, those observed just before swallowing seem to be involved in swallowing initiation. They can be considered as strong candidates for sensory inputs from the bolus that are probably crucially involved in the triggering of swallowing, since they appeared in boluses prepared in various mastication strategies by different subjects.

  4. Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

    PubMed Central

    Brangwynne, Clifford P.; Mitchison, Timothy J.; Hyman, Anthony A.

    2011-01-01

    For most intracellular structures with larger than molecular dimensions, little is known about the connection between underlying molecular activities and higher order organization such as size and shape. Here, we show that both the size and shape of the amphibian oocyte nucleolus ultimately arise because nucleoli behave as liquid-like droplets of RNA and protein, exhibiting characteristic viscous fluid dynamics even on timescales of < 1 min. We use these dynamics to determine an apparent nucleolar viscosity, and we show that this viscosity is ATP-dependent, suggesting a role for active processes in fluidizing internal contents. Nucleolar surface tension and fluidity cause their restructuring into spherical droplets upon imposed mechanical deformations. Nucleoli exhibit a broad distribution of sizes with a characteristic power law, which we show is a consequence of spontaneous coalescence events. These results have implications for the function of nucleoli in ribosome subunit processing and provide a physical link between activity within a macromolecular assembly and its physical properties on larger length scales. PMID:21368180

  5. Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes.

    PubMed

    Brangwynne, Clifford P; Mitchison, Timothy J; Hyman, Anthony A

    2011-03-15

    For most intracellular structures with larger than molecular dimensions, little is known about the connection between underlying molecular activities and higher order organization such as size and shape. Here, we show that both the size and shape of the amphibian oocyte nucleolus ultimately arise because nucleoli behave as liquid-like droplets of RNA and protein, exhibiting characteristic viscous fluid dynamics even on timescales of < 1 min. We use these dynamics to determine an apparent nucleolar viscosity, and we show that this viscosity is ATP-dependent, suggesting a role for active processes in fluidizing internal contents. Nucleolar surface tension and fluidity cause their restructuring into spherical droplets upon imposed mechanical deformations. Nucleoli exhibit a broad distribution of sizes with a characteristic power law, which we show is a consequence of spontaneous coalescence events. These results have implications for the function of nucleoli in ribosome subunit processing and provide a physical link between activity within a macromolecular assembly and its physical properties on larger length scales.

  6. Direction of Translation and Size of Bacteriophage φX174 Cistrons

    PubMed Central

    Benbow, Robert M.; Mayol, Robert F.; Picchi, Joanna C.; Sinsheimer, Robert L.

    1972-01-01

    Translation of the bacteriophage φX174 genome follows cistron order D-E-F-G-H-A-B-C. To establish this, the position of a nonsense mutation on the genetic map was compared with the physical size (molecular weight) of the appropriate protein fragment generated in nonpermissive cells. Distances on the φX174 genetic map and distances on a physical map constructed from the molecular weights of φX174 proteins and protein fragments are proportional over most of the genome with the exception of the high recombination region within cistron A. Images PMID:16789133

  7. Investigation of pore size and energy distributions by statistical physics formalism applied to agriculture products

    NASA Astrophysics Data System (ADS)

    Aouaini, Fatma; Knani, Salah; Yahia, Manel Ben; Bahloul, Neila; Ben Lamine, Abdelmottaleb; Kechaou, Nabil

    2015-12-01

    In this paper, we present a new investigation that allows determining the pore size distribution (PSD) in a porous medium. This PSD is achieved by using the desorption isotherms of four varieties of olive leaves. This is by the means of statistical physics formalism and Kelvin's law. The results are compared with those obtained with scanning electron microscopy. The effect of temperature on the distribution function of pores has been studied. The influence of each parameter on the PSD is interpreted. A similar function of adsorption energy distribution, AED, is deduced from the PSD.

  8. Particle Size Measurements From the First Fundamentals of Ice Crystal Icing Physics Test in the NASA Propulsion Systems Laboratory

    NASA Technical Reports Server (NTRS)

    King, Michael C.; Bachalo, William; Kurek, Andrzej

    2017-01-01

    This paper presents particle measurements by the Artium Technologies, Inc. Phase Doppler Interferometer and High Speed Imaging instruments from the first Fundamental Ice Crystal Icing Physics test conducted in the NASA Propulsion Systems Laboratory. The work focuses on humidity sweeps at a larger and a smaller median volumetric diameter. The particle size distribution, number density, and water content measured by the Phase Doppler Interferometer and High Speed Imaging instruments from the sweeps are presented and compared. The current capability for these two instruments to measure and discriminate ICI conditions is examined.

  9. Particle Size Measurements from the first Fundamentals of Ice Crystal Icing Physics Test in the NASA Propulsion Systems Laboratory

    NASA Technical Reports Server (NTRS)

    King, Michael C.; Bachalo, William; Kurek, Andrzej

    2017-01-01

    This presentation shows particle measurements by the Artium Technologies, Inc. Phase Doppler Interferometer and High Speed Imaging instruments from the first Fundamental Ice Crystal Icing Physics test conducted in the NASA Propulsion Systems Laboratory. The work focuses on humidity sweeps at a larger and a smaller median volumetric diameter. The particle size distribution, number density, and water content measured by the Phase Doppler Interferometer and High Speed Imaging instruments from the sweeps are presented and compared. The current capability for these two instruments to measure and discriminate ICI conditions is examined.

  10. Comparison of quality of life between two clinical conditions with immunosuppressive therapy: liver transplantation and multiple sclerosis.

    PubMed

    Fernández-Jiménez, E; Pérez-San-Gregorio, M A; Martín-Rodríguez, A; Domínguez-Cabello, E; Navarro-Mascarell, G; Bernardos-Rodríguez, A

    2012-11-01

    We aimed to compare quality of life in two clinical conditions treated with immunosuppressants: cadaveric liver transplant recipients and multiple sclerosis patients. We also assessed the clinical significance of these results regarding a representative age-adjusted sample of the general Spanish population. Using a cross-sectional design, the SF-36 Health Survey was used to evaluate 62 patients with these chronic conditions (31 in each group) who were matched for gender. An analysis of covariance was performed to control for the influence of time from multiple sclerosis diagnosis and liver transplantation surgery until assessment. Student t test of covariate-adjusted mean values was used as the statistical test and Cohen's d effect size index, to assess the magnitude of intergroup differences and assess clinical significance. Significantly worse scores were observed among the neurological patients compared with transplant recipients regarding role-physical (P = .038), general health (P = .003), vitality (P = .034), and physical functioning (P = .049), with medium effect sizes (Cohen's ds from -0.511 to -0.785). Against normative values, liver transplant recipients displayed relevant differences in all SF-36 subscales (Cohen's ds from -0.569 to -0.974) except for mental health (small effect size). Likewise, multiple sclerosis patients showed much greater differences versus the general population (Cohen's ds from -0.846 to -1.760). Liver transplant recipients showed better quality of life than multiple sclerosis patients (medium effect sizes) in physical quality-of-life dimensions. Interestingly, despite having controlled for time from diagnosis/transplantation, both medical conditions showed clinically significant impairments (large and medium effect sizes) in physical and psychosocial quality-of-life domains. We concluded that transplant recipients belong to a population that still requires special health care because, even after having undergone their treatment of choice, they do not achieve normal levels of biopsychosocial functioning. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. Adolescents' attitudes toward sports, exercise, and fitness predict physical activity 5 and 10 years later.

    PubMed

    Graham, Dan J; Sirard, John R; Neumark-Sztainer, Dianne

    2011-02-01

    To determine whether adolescent attitudes towards sports, exercise, and fitness predict moderate-to-vigorous physical activity 5 and 10 years later. A diverse group of 1902 adolescents participating in Project Eating and Activity in Teens, reported weekly moderate-to-vigorous physical activity and attitudes toward sports, exercise, and fitness in Eating and Activity in Teens-I (1998-99), Eating and Activity in Teens-II (2003-04), and Eating and Activity in Teens-III (2008-09). Mean moderate-to-vigorous physical activity was 6.4, 5.1, and 4.0 hours/week at baseline, 5-year, and 10-year follow-up, respectively. Attitudes toward sports, exercise, and fitness together predicted moderate-to-vigorous physical activity at 5 and 10 years. Among the predictors of 5- and 10-year moderate-to-vigorous physical activity, attitude's effect size, though modest, was comparable to the effect sizes for sports participation and body mass index. Adolescents with more-favorable attitudes toward sports, exercise, and fitness engaged in approximately 30%-40% more weekly moderate-to-vigorous physical activity at follow-up (2.1 hour/week at 5 years and 1.2 hour/week at 10 years) than those with less-favorable attitudes. Adolescents' exercise-related attitudes predict subsequent moderate-to-vigorous physical activity independent of baseline behavior suggesting that youth moderate-to-vigorous physical activity promotion efforts may provide long-term benefits by helping youth develop favorable exercise attitudes. Copyright © 2010 Elsevier Inc. All rights reserved.

  12. Size dependence of the propulsion velocity for catalytic Janus-sphere swimmers.

    PubMed

    Ebbens, Stephen; Tu, Mei-Hsien; Howse, Jonathan R; Golestanian, Ramin

    2012-02-01

    The propulsion velocity of active colloids that asymmetrically catalyze a chemical reaction is probed experimentally as a function of their sizes. It is found that over the experimentally accessible range, the velocity decays as a function of size, with a rate that is compatible with an inverse size dependence. A diffusion-reaction model for the concentrations of the fuel and waste molecules that takes into account a two-step process for the asymmetric catalytic activity on the surface of the colloid is shown to predict a similar behavior for colloids at the large size limit, with a saturation for smaller sizes. © 2012 American Physical Society

  13. Electric Motorboat Drag Racing: A Hands-On Physics Project that Motivates Students from Start to Finish

    ERIC Educational Resources Information Center

    Barry, Reno

    2008-01-01

    Electric Motorboat Drag Racing is a culminating high school physics project designed to apply and bring to life many content standards for physics. Students need to be given several weeks at home to design and build their model-sized electric motorboats for the 5-meter drag racing competition down rain gutters. In the process, they are discussing…

  14. Growth of urea crystals by physical vapor transport

    NASA Technical Reports Server (NTRS)

    Feigelson, R. S.; Route, R. K.; Kao, T.-M.

    1985-01-01

    This work demonstrates that high optical quality crystals of urea can be grown by the physical vapor transport method. The unique features of this method are compared with growth from methanol/water solutions. High growth rates, exceeding 2.5 mm/day, were achieved, and cm-size optical quality single crystals were obtained. Details of the growth technique and the physical properties of the crystals are presented.

  15. Adolescent Athleticism, Exercise, Body Image, and Dietary Practices.

    ERIC Educational Resources Information Center

    Rainey, Cheryl J.; McKeown, Robert E.; Sargent, Roger G.; Valois, Robert F.

    1998-01-01

    Investigated relationships between physical activity and athletic participation and body-size perceptions, diet, and weight-control practice among high school students, noting racial and gender differences. Surveys indicated that diet quality improved and weight-loss attempts increased as physical activity and athletic participation increased.…

  16. Physical-depth architectural requirements for generating universal photonic cluster states

    NASA Astrophysics Data System (ADS)

    Morley-Short, Sam; Bartolucci, Sara; Gimeno-Segovia, Mercedes; Shadbolt, Pete; Cable, Hugo; Rudolph, Terry

    2018-01-01

    Most leading proposals for linear-optical quantum computing (LOQC) use cluster states, which act as a universal resource for measurement-based (one-way) quantum computation. In ballistic approaches to LOQC, cluster states are generated passively from small entangled resource states using so-called fusion operations. Results from percolation theory have previously been used to argue that universal cluster states can be generated in the ballistic approach using schemes which exceed the critical threshold for percolation, but these results consider cluster states with unbounded size. Here we consider how successful percolation can be maintained using a physical architecture with fixed physical depth, assuming that the cluster state is continuously generated and measured, and therefore that only a finite portion of it is visible at any one point in time. We show that universal LOQC can be implemented using a constant-size device with modest physical depth, and that percolation can be exploited using simple pathfinding strategies without the need for high-complexity algorithms.

  17. Undersampling power-law size distributions: effect on the assessment of extreme natural hazards

    USGS Publications Warehouse

    Geist, Eric L.; Parsons, Thomas E.

    2014-01-01

    The effect of undersampling on estimating the size of extreme natural hazards from historical data is examined. Tests using synthetic catalogs indicate that the tail of an empirical size distribution sampled from a pure Pareto probability distribution can range from having one-to-several unusually large events to appearing depleted, relative to the parent distribution. Both of these effects are artifacts caused by limited catalog length. It is more difficult to diagnose the artificially depleted empirical distributions, since one expects that a pure Pareto distribution is physically limited in some way. Using maximum likelihood methods and the method of moments, we estimate the power-law exponent and the corner size parameter of tapered Pareto distributions for several natural hazard examples: tsunamis, floods, and earthquakes. Each of these examples has varying catalog lengths and measurement thresholds, relative to the largest event sizes. In many cases where there are only several orders of magnitude between the measurement threshold and the largest events, joint two-parameter estimation techniques are necessary to account for estimation dependence between the power-law scaling exponent and the corner size parameter. Results indicate that whereas the corner size parameter of a tapered Pareto distribution can be estimated, its upper confidence bound cannot be determined and the estimate itself is often unstable with time. Correspondingly, one cannot statistically reject a pure Pareto null hypothesis using natural hazard catalog data. Although physical limits to the hazard source size and by attenuation mechanisms from source to site constrain the maximum hazard size, historical data alone often cannot reliably determine the corner size parameter. Probabilistic assessments incorporating theoretical constraints on source size and propagation effects are preferred over deterministic assessments of extreme natural hazards based on historic data.

  18. Challenges for Physical Characterization of Silver Nanoparticles Under Pristine and Environmentally Relevant Conditions

    EPA Science Inventory

    The reported size distribution of silver nanoparticles (AgNPs) is strongly affected by the underlying measurement method, agglomeration state, and dispersion conditions. A selection of AgNP materials with vendor-reported diameters ranging from 1 nm to 100 nm, various size distrib...

  19. Gender differences in health-related quality of life of Australian chronically-ill adults: patient and physician characteristics do matter.

    PubMed

    Jayasinghe, Upali W; Harris, Mark F; Taggart, Jane; Christl, Bettina; Black, Deborah A

    2013-06-21

    The aims of this study were to explore the health-related quality of life (HRQoL) in a large sample of Australian chronically-ill patients (type 2 diabetes and/or hypertension/ischaemic heart disease), to investigate the impact of characteristics of patients and their general practitioners on their HRQoL and to examine clinically significant differences in HRQoL among males and females. This was a cross-sectional study with 193 general practitioners and 2181 of their chronically-ill patients aged 18 years or more using the standard Short Form Health Survey (SF-12) version 2. SF-12 physical component score (PCS-12) and mental component score (MCS-12) were derived using the standard US algorithm. Multilevel regression analysis (patients at level 1 and general practitioners at level 2) was applied to relate PCS-12 and MCS-12 to patient and general practitioner (GP) characteristics. Employment was likely to have a clinically significant larger positive effect on HRQoL of males (regression coefficient (B) (PCS-12) = 7.29, P < 0.001, effect size = 1.23 and B (MCS-12) = 3.40, P < 0.01, effect size = 0.55) than that of females (B(PCS-12) = 4.05, P < 0.001, effect size = 0.78 and B (MCS-12) = 1.16, P > 0.05, effect size = 0.16). There was a clinically significant difference in HRQoL among age groups. Younger men (< 39 years) were likely to have better physical health than older men (> 59 years, B = -5.82, P < 0.05, effect size = 0.66); older women tended to have better mental health (B = 5.62, P < 0.001, effect size = 0.77) than younger women. Chronically-ill women smokers reported clinically significant (B = -3.99, P < 0.001, effect size = 0.66) poorer mental health than women who were non-smokers. Female GPs were more likely to examine female patients than male patients (33% vs. 15%, P < 0.001) and female patients attending female GPs reported better physical health (B = 1.59, P < 0.05, effect size = 0.30). Some of the associations between patient characteristics and SF-12 physical and/or mental component scores were different for men and women. This finding underlines the importance of considering these factors in the management of chronically-ill patients in general practice. The results suggest that chronically ill women attempting to quit smoking may need more psychological support. More quantitative studies are needed to determine the association between GP gender and patient gender in relation to HRQoL.

  20. Models of Individual Dietary Behavior Based on Smartphone Data: The Influence of Routine, Physical Activity, Emotion, and Food Environment

    PubMed Central

    Seto, Edmund; Hua, Jenna; Wu, Lemuel; Shia, Victor; Eom, Sue; Wang, May; Li, Yan

    2016-01-01

    Introduction Smartphone applications (apps) facilitate the collection of data on multiple aspects of behavior that are useful for characterizing baseline patterns and for monitoring progress in interventions aimed at promoting healthier lifestyles. Individual-based models can be used to examine whether behavior, such as diet, corresponds to certain typological patterns. The objectives of this paper are to demonstrate individual-based modeling methods relevant to a person’s eating behavior, and the value of such approach compared to typical regression models. Method Using a mobile app, 2 weeks of physical activity and ecological momentary assessment (EMA) data, and 6 days of diet data were collected from 12 university students recruited from a university in Kunming, a rapidly developing city in southwest China. Phone GPS data were collected for the entire 2-week period, from which exposure to various food environments along each subject’s activity space was determined. Physical activity was measured using phone accelerometry. Mobile phone EMA was used to assess self-reported emotion/feelings. The portion size of meals and food groups was determined from voice-annotated videos of meals. Individual-based regression models were used to characterize subjects as following one of 4 diet typologies: those with a routine portion sizes determined by time of day, those with portion sizes that balance physical activity (energy balance), those with portion sizes influenced by emotion, and those with portion sizes associated with food environments. Results Ample compliance with the phone-based behavioral assessment was observed for all participants. Across all individuals, 868 consumed food items were recorded, with fruits, grains and dairy foods dominating the portion sizes. On average, 218 hours of accelerometry and 35 EMA responses were recorded for each participant. For some subjects, the routine model was able to explain up to 47% of the variation in portion sizes, and the energy balance model was able to explain over 88% of the variation in portion sizes. Across all our subjects, the food environment was an important predictor of eating patterns. Generally, grouping all subjects into a pooled model performed worse than modeling each individual separately. Conclusion A typological modeling approach was useful in understanding individual dietary behaviors in our cohort. This approach may be applicable to the study of other human behaviors, particularly those that collect repeated measures on individuals, and those involving smartphone-based behavioral measurement. PMID:27049852

  1. Geometry, packing, and evolutionary paths to increased multicellular size

    NASA Astrophysics Data System (ADS)

    Jacobeen, Shane; Graba, Elyes C.; Brandys, Colin G.; Day, Thomas C.; Ratcliff, William C.; Yunker, Peter J.

    2018-05-01

    The evolutionary transition to multicellularity transformed life on earth, heralding the evolution of large, complex organisms. Recent experiments demonstrated that laboratory-evolved multicellular "snowflake yeast" readily overcome the physical barriers that limit cluster size by modifying cellular geometry [Jacobeen et al., Nat. Phys. 14, 286 (2018), 10.1038/s41567-017-0002-y]. However, it is unclear why this route to large size is observed, rather than an evolved increase in intercellular bond strength. Here, we use a geometric model of the snowflake yeast growth form to examine the geometric efficiency of increasing size by modifying geometry and bond strength. We find that changing geometry is a far more efficient route to large size than evolving increased intercellular adhesion. In fact, increasing cellular aspect ratio is on average ˜13 times more effective than increasing bond strength at increasing the number of cells in a cluster. Modifying other geometric parameters, such as the geometric arrangement of mother and daughter cells, also had larger effects on cluster size than increasing bond strength. Simulations reveal that as cells reproduce, internal stress in the cluster increases rapidly; thus, increasing bond strength provides diminishing returns in cluster size. Conversely, as cells become more elongated, cellular packing density within the cluster decreases, which substantially decreases the rate of internal stress accumulation. This suggests that geometrically imposed physical constraints may have been a key early selective force guiding the emergence of multicellular complexity.

  2. Seeing big things: overestimation of heights is greater for real objects than for objects in pictures

    NASA Technical Reports Server (NTRS)

    Yang, T. L.; Dixon, M. W.; Proffitt, D. R.; Kaiser, M. K. (Principal Investigator)

    1999-01-01

    In six experiments we demonstrate that the vertical-horizontal illusion that is evoked when viewing photographs and line drawings is relatively small, whereas the magnitude of this illusion when large objects are viewed is at least twice as great. Furthermore, we show that the illusion is due more to vertical overestimation than horizontal underestimation. The lack of a difference in vertical overestimation between pictures and line drawings suggests that vertical overestimation in pictures depends solely on the perceived physical size of the projection on the picture surface, rather than on what is apparent about an object's represented size. The vertical-horizontal illusion is influenced by perceived physical size. It is greater when viewing large objects than small pictures of these same objects, even when visual angles are equated.

  3. Dimension-dependent stimulated radiative interaction of a single electron quantum wavepacket

    NASA Astrophysics Data System (ADS)

    Gover, Avraham; Pan, Yiming

    2018-06-01

    In the foundation of quantum mechanics, the spatial dimensions of electron wavepacket are understood only in terms of an expectation value - the probability distribution of the particle location. One can still inquire how the quantum electron wavepacket size affects a physical process. Here we address the fundamental physics problem of particle-wave duality and the measurability of a free electron quantum wavepacket. Our analysis of stimulated radiative interaction of an electron wavepacket, accompanied by numerical computations, reveals two limits. In the quantum regime of long wavepacket size relative to radiation wavelength, one obtains only quantum-recoil multiphoton sidebands in the electron energy spectrum. In the opposite regime, the wavepacket interaction approaches the limit of classical point-particle acceleration. The wavepacket features can be revealed in experiments carried out in the intermediate regime of wavepacket size commensurate with the radiation wavelength.

  4. Beam parameter optimization at CLIC using the process e+e- → HZ → Hq q bar at 380 GeV

    NASA Astrophysics Data System (ADS)

    Andrianala, F.; Raboanary, R.; Roloff, P.; Schulte, D.

    2017-01-01

    At CLIC and the ILC beam-beam forces lead to the emission of beamstrahlung photons and a reduction of the effective center-of-mass energy. This degradation is controlled by the choice of the horizontal beam size. A reduction of this parameter would increase the luminosity but also the beamstrahlung. In this paper the optimum choice for the horizontal beam size is investigated for one of the most important physics processes. The Higgsstrahlung process e+e- → HZ is identified in a model-independent manner by observing the Z boson and determining the mass against which it is recoiling. The physics analysis for this process is performed for constant running times, assuming different beam size and taking into account the resulting levels of integrated luminosity and the associated luminosity spectra.

  5. A procedure for classifying textural facies in gravel‐bed rivers

    USGS Publications Warehouse

    Buffington, John M.; Montgomery, David R.

    1999-01-01

    Textural patches (i.e., grain‐size facies) are commonly observed in gravel‐bed channels and are of significance for both physical and biological processes at subreach scales. We present a general framework for classifying textural patches that allows modification for particular study goals, while maintaining a basic degree of standardization. Textures are classified using a two‐tier system of ternary diagrams that identifies the relative abundance of major size classes and subcategories of the dominant size. An iterative procedure of visual identification and quantitative grain‐size measurement is used. A field test of our classification indicates that it affords reasonable statistical discrimination of median grain size and variance of bed‐surface textures. We also explore the compromise between classification simplicity and accuracy. We find that statistically meaningful textural discrimination requires use of both tiers of our classification. Furthermore, we find that simplified variants of the two‐tier scheme are less accurate but may be more practical for field studies which do not require a high level of textural discrimination or detailed description of grain‐size distributions. Facies maps provide a natural template for stratifying other physical and biological measurements and produce a retrievable and versatile database that can be used as a component of channel monitoring efforts.

  6. Self body-size perception in an insect

    NASA Astrophysics Data System (ADS)

    Ben-Nun, Amir; Guershon, Moshe; Ayali, Amir

    2013-05-01

    Animals negotiating complex environments encounter a wide range of obstacles of different shapes and sizes. It is greatly beneficial for the animal to react to such obstacles in a precise, context-specific manner, in order to avoid harm or even simply to minimize energy expenditure. An essential key challenge is, therefore, an estimation of the animal's own physical characteristics, such as body size. A further important aspect of self body-size perception (or SBSP) is the need to update it in accordance with changes in the animal's size and proportions. Despite the major role of SBSP in functional behavior, little is known about if and how it is mediated. Here, we demonstrate that insects are also capable of self perception of body size and that this is a vital factor in allowing them to adjust their behavior following the sudden and dramatic growth associated with periodic molting. We reveal that locusts' SBSP is strongly correlated with their body size. However, we show that the dramatic change in size accompanying adult emergence is not sufficient to create a new and updated SBSP. Rather, this is created and then consolidated only following the individuals' experience and interaction with the physical environment. Behavioral or pharmacological manipulations can both result in maintenance of the old larval SBSP. Our results emphasize the importance of learning and memory-related processes in the development and update of SBSP, and highlight the advantage of insects as good models for a detailed study on the neurobiological and molecular aspects of SBSP.

  7. Place of residence as a factor differentiating physical activity in the life style of Ukrainian students.

    PubMed

    Bergier, Józef; Bergier, Barbara; Tsos, Anatolii

    2016-12-23

    Determining the state of physical activity of societies as an important component of a health promoting life style is a very up-to-date problem. Studies of physical activity among students, the future elites in their environments, become of increasing importance. An important problem is the recognition of factors differentiating this activity on the example of place of residence. For this purpose, the study covered 2,125 students (60.8% females and 39.2% males) from the National Institute in Lutsk, Ukraine, aged 17-22 (mean age: 20.4). The method of a diagnostic survey was applied which included the International Physical Activity Questionnaire (IPAQ). The following measures of physical activity according to the place of residence (rural area, small town with a population up to 100,000; medium-size town - 100,000-200,000 inhabitants; large city - over 200,000) were taken into consideration: level of physical activity, self-reported physical fitness, sports disciplines practiced by the respondents, and those which they would like to practice, and the BMI, and leisure time possessed. The study showed that the place of residence positively differentiated physical activity among students from medium-size towns and rural areas, compared to their contemporaries from small towns and large cities. Significant differences were also found with respect to the BMI, which was significantly less favourable among respondents from the rural environment. However, no differences were observed between the place of residence for leisure time, self-reported physical activity, and forms of physical activity practiced, and those which the respondents would like to practice.

  8. Effect of crumb-rubber particle size on mechanical response of polyurethane foam composites

    NASA Astrophysics Data System (ADS)

    Sanjay, Omer Sheik

    The compression properties of foam are governed by by three factors: i) cell edge bending ii) compression of cell fluid iii) membrane stresses in the cell faces. The effect of reinforcement, granular form of scrap tire rubber on contribution of each of these effects along with the physical properties of polyurethane foam is investigated. It is seen that the addition of crumb-rubber hinders the formation of cell membranes during the foaming process. Four different sizes of particles were chosen to closely study the effect of particle size on the physical properties of the foam composite. There is a definite pattern seen in each of the physical property of the composite with change in the particle size. Addition of crumb-rubber decreases the compressive strength but in turn increases the elastic modulus of the composite. The rubber particles act as the sites for stress concentration and hence the inclusion of rubber particles induces the capability to transfer the axial load laterally along the surface of the foam. Also, the filler material induces porosity into the foam, which is seen in the SEM images, and hence the addition of rubber particles induces brittleness, which makes the foam composites extensively applicable for structural application in sandwich components. The lightweight composite therefore is a potential substitute to the heavier metal foams and honeycombs as a protective layer.

  9. Nanostructured silicon membranes for control of molecular transport.

    PubMed

    Srijanto, Bernadeta R; Retterer, Scott T; Fowlkes, Jason D; Doktycz, Mitchel J

    2010-11-01

    A membrane that allows selective transport of molecular species requires precise engineering on the nanoscale. Membrane permeability can be tuned by controlling the physical structure and surface chemistry of the pores. Here, a combination of electron beam and optical lithography, along with cryogenic deep reactive ion etching, has been used to fabricate silicon membranes that are physically robust, have uniform pore sizes, and are directly integrated into a microfluidic network. Additional reductions in pore size were achieved using plasma enhanced chemical vapor deposition and atomic layer deposition of silicon dioxide to coat membrane surfaces. Cross sectioning of the membranes using focused ion beam milling was used to determine the physical shape of the membrane pores before and after coating. Functional characterization of the membranes was performed by using quantitative fluorescence microscopy to document the transport of molecular species across the membrane.

  10. Liposuction induces a compensatory increase of visceral fat which is effectively counteracted by physical activity: a randomized trial.

    PubMed

    Benatti, Fabiana; Solis, Marina; Artioli, Guilherme; Montag, Eduardo; Painelli, Vitor; Saito, Fábio; Baptista, Luciana; Costa, Luiz Augusto; Neves, Rodrigo; Seelaender, Marília; Ferriolli, Eduardo; Pfrimer, Karina; Lima, Fernanda; Roschel, Hamilton; Gualano, Bruno; Lancha, Antonio

    2012-07-01

    Liposuction is suggested to result in long-term body fat regain that could lead to increased cardiometabolic risk. We hypothesized that physical activity could prevent this effect. Our objective was to investigate the effects of liposuction on body fat distribution and cardiometabolic risk factors in women who were either exercise trained or not after surgery. Thirty-six healthy normal-weight women participated in this 6-month randomized controlled trial at the University of Sao Paulo, Sao Paulo, Brazil. Patients underwent a small-volume abdominal liposuction. Two months after surgery, the subjects were randomly allocated into two groups: trained (TR, n = 18, 4-month exercise program) and nontrained (NT, n = 18). Body fat distribution (assessed by computed tomography) was assessed before the intervention (PRE) and 2 months (POST2), and 6 months (POST6) after surgery. Secondary outcome measures included body composition, metabolic parameters and dietary intake, assessed at PRE, POST2, and POST6, and total energy expenditure, physical capacity, and sc adipocyte size and lipid metabolism-related gene expression, assessed at PRE and POST6. Liposuction was effective in reducing sc abdominal fat (PRE vs. POST2, P = 0.0001). Despite the sustained sc abdominal fat decrement at POST6 (P = 0.0001), the NT group showed a significant 10% increase in visceral fat from PRE to POST6 (P = 0.04; effect size = -0.72) and decreased energy expenditure (P = 0.01; effect size = 0.95) when compared with TR. Dietary intake, adipocyte size, and gene expression were unchanged over time. Abdominal liposuction does not induce regrowth of fat, but it does trigger a compensatory increase of visceral fat, which is effectively counteracted by physical activity.

  11. Can Minor Merging Account for the Size Growth of Quiescent Galaxies? New Results from the CANDELS Survey

    NASA Astrophysics Data System (ADS)

    Newman, Andrew B.; Ellis, Richard S.; Bundy, Kevin; Treu, Tommaso

    2012-02-01

    The presence of extremely compact galaxies at z ~ 2 and their subsequent growth in physical size has been the cause of much puzzlement. We revisit the question using deep infrared Wide Field Camera 3 data to probe the rest-frame optical structure of 935 galaxies selected with 0.4 < z < 2.5 and stellar masses M * > 1010.7 M ⊙ in the UKIRT Ultra Deep Survey and GOODS-South fields of the CANDELS survey. At each redshift, the most compact sources are those with little or no star formation, and the mean size of these systems at fixed stellar mass grows by a factor of 3.5 ± 0.3 over this redshift interval. The data are sufficiently deep to identify companions to these hosts whose stellar masses are ten times smaller. By searching for these around 404 quiescent hosts within a physical annulus 10 h -1 kpc < R < 30 h -1 kpc, we estimate the minor merger rate over 0.4 < z < 2. We find that 13%-18% of quiescent hosts have likely physical companions with stellar mass ratios of 0.1 or greater. Mergers of these companions will typically increase the host mass by 6% ± 2% per merger timescale. We estimate the minimum growth rate necessary to explain the declining abundance of compact galaxies. Using a simple model motivated by recent numerical simulations, we then assess whether mergers of the faint companions with their hosts are sufficient to explain this minimal rate. We find that mergers may explain most of the size evolution observed at z <~ 1 if a relatively short merger timescale is assumed, but the rapid growth seen at higher redshift likely requires additional physical processes.

  12. Size, skills, and suffrage: Motivated distortions in perceived formidability of political leaders

    PubMed Central

    Blaker, Nancy M.; Pollet, Thomas V.

    2017-01-01

    Research shows that perception of physical size and status are positively associated. The current study was developed to replicate and extend earlier research on height perceptions of political leaders, indicating that supporters perceive their leaders as taller than non-supporters do, and winners are perceived as taller after the elections, while losers are perceived as shorter after the elections (winner/loser effects). Individuals use greater height and strength as indications of greater physical formidability. We hypothesized that in-group leaders’ height and strength, but not weight, would be overestimated more compared to out-group leaders’, and that this status-size association is not only driven by dominance, but also by prestige. We also tested whether previously found gender effects in estimates were due to using one’s own height as an anchor, and we used an improved methodological approach by relying on multiple measurements of physical formidability and a within-subject design for testing winner/loser effects. The results of a two-part longitudinal study (self-selected sample via voting advice website; NWave1 = 2,011; NWave2 = 322) suggest that estimated physical formidability of political leaders is affected by motivated perception, as prestige was positively associated with estimated formidability, and in-group leaders were estimated more formidable than out-group leaders. We conclude that distortions in judged formidability related to social status are the result of motivated social perception in order to promote group functioning and leadership. Although we did not replicate a winner-effect (greater estimations of formidability after winning the elections), we did find some evidence for a loser-effect. Earlier suggestions that men make larger estimations than women because of their own larger body size are not supported. Implications for theory and future research are discussed. PMID:29267275

  13. Responsiveness of physical function outcomes following physiotherapy intervention for osteoarthritis of the knee: an outcome comparison study.

    PubMed

    French, Helen P; Fitzpatrick, Martina; FitzGerald, Oliver

    2011-12-01

    To compare the responsiveness of two self-report measures and three physical performance measures of function following physiotherapy for osteoarthritis of the knee. Single centre study in acute hospital setting. Patients referred for physiotherapy with osteoarthritis of the knee were recruited. The Western Ontario and McMaster Universities (WOMAC), Lequesne Algofunctional Index (LAI), timed-up-and-go test (TUGT), timed-stand test (TST) and six-minute walk test (6MWT) were administered at first and final physiotherapy visits. Wilcoxon Signed Rank tests were used to determine the effect of physiotherapy on each outcome. Responsiveness was calculated using effect size, standardised response mean and a median-based measure of responsiveness due to some outlying data. Thirty-nine patients with a mean age of 65.3 (standard deviation 6.9) years were investigated before and after a course of exercise-based physiotherapy. There was a significant improvement in all outcomes except the WOMAC scores. All measures demonstrated small effect sizes for all statistics (<0.50), except the 6MWT which was in the moderate range for one of the indices (standardised response mean 0.54). The LAI was more responsive than the WOMAC total score and the WOMAC physical function subscale for all responsiveness statistics, whilst the 6MWT was more responsive than the TST and the TUGT. The median-based effect size index produced the smallest effect sizes for all measures (0.1 to 0.43). These results can be used to guide decision making about which physical function outcome measures should be used to evaluate effectiveness of rehabilitation of people with osteoarthritis of the knee at group level in a clinical setting. Copyright © 2010 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  14. [The impact of a 14- day regular physical exercise regime on the concentration of the classes and subclasses of lipoprotein particles in young subjects with a sedentary lifestyle].

    PubMed

    Sabaka, P; Dukát, A; Oravec, S; Mistríková, L; Baláž, D; Bendžala, M; Gašpar, L

    2013-10-01

    Recommendations from the cardiological professional companies working in the area of primary prevention of cardiovascular diseases put an emphasis on regular aerobic physical activity. Its positive effect on both cardiovascular and overall mortality has repea-tedly been proven by the observations of prospective and cross sectional epidemiological studies. One of the possible explanations of this positive effect is a change in the concentration of lipoprotein classes and their subclasses, which is expressed as a change in their average size. In a group of young healthy men and women with a sedentary lifestyle we observed the effect of medium intensive physical exercise in the form of a 30- minute slow run per day lasting for 14 days. The concentration of lipoprotein classes and subclasses were determined through the method of a linear electrophoresis in polyacrylamide gel. In the observed group we found a statistically significant decrease of VLDL, large IDL particles, medium sized LDL, small dense LDL, and medium sized HDL particles. In the light of current knowledge all these lipoprotein particles are deemed as atherogenic. Thus, as little as 14 days of regular exercising has a positive effect on the concentration of plasmatic lipoproteins, and emphasises the role of regular physical activity in the primary prevention of cardiovascular diseases.

  15. Ultra-High Pressure Homogenization enhances physicochemical properties of soy protein isolate-stabilized emulsions.

    PubMed

    Fernández-Ávila, C; Escriu, R; Trujillo, A J

    2015-09-01

    The effect of Ultra-High Pressure Homogenization (UHPH, 100-300MPa) on the physicochemical properties of oil-in-water emulsions prepared with 4.0% (w/v) of soy protein isolate (SPI) and soybean oil (10 and 20%, v/v) was studied and compared to emulsions treated by conventional homogenization (CH, 15MPa). CH emulsions were prepared with non-heated and heated (95°C for 15min) SPI dispersions. Emulsions were characterized by particle size determination with laser diffraction, rheological properties using a rotational rheometer by applying measurements of flow curve and by transmission electron microscopy. The variation on particle size and creaming was assessed by Turbiscan® analysis, and visual observation of the emulsions was also carried out. UHPH emulsions showed much smaller d 3.2 values and greater physical stability than CH emulsions. The thermal treatment of SPI prior CH process did not improve physical stability properties. In addition, emulsions containing 20% of oil exhibited greater physical stability compared to emulsions containing 10% of oil. Particularly, UHPH emulsions treated at 100 and 200MPa with 20% of oil were the most stable due to low particle size values (d 3.2 and Span), greater viscosity and partial protein denaturation. These results address the physical stability improvement of protein isolate-stabilized emulsions by using the emerging UHPH technology. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Detecting Habitats and Ecosystem Functions Considering the Mesozooplankton Size and Diversity Structures and Environmental Conditions in the Gulf of Lion, NW Mediterranean Sea

    NASA Astrophysics Data System (ADS)

    Carlotti, F.; Espinasse, B.; Zhou, M.; Jean-Luc, D.

    2016-02-01

    Environmental conditions and zooplankton size structure and taxonomic diversity were investigated in the Gulf of Lion in May 2010 and January 2011. The integrated physical and biological measurements provided a 3D view with high spatial resolution of the physical and biological variables and their correlations over the whole gulf. The effects of physical processes such as freshwater input, coastal upwelling, and water column mixing by winds on phytoplankton and zooplankton distributions were analyzed using these data. Several analytic tests were performed in order to define several ecoregions representing different habitats of plankton communities. Three habitats were distinguished based on statistical analysis performed on biological and physical variables: (1) the coastal area characterized by shallow waters, high chl a concentrations, and a steep slope of the normalized biomass size spectrum (NBSS); (2) the area affected by the Rhône with high stratification and flat NBSS slope; and (3) the continental shelf with a deep mixed layer, relatively low particle concentrations, and moderate NBSS slope. The zooplankton diversity was characterized by spatial differences in community composition among the Rhône plume area, the coastal shelf, and shelf break waters. Defining habitat is a relevant approach to designing new zooplankton sampling strategies, validating distribution models and including the zooplankton compartment in trophodynamic studies.

  17. 40 CFR 221.1 - Applications for permits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... Applications for general, special, emergency, and research permits under section 102 of the Act may be filed... equipment; (c) Adequate physical and chemical description of material to be dumped, including results of tests necessary to apply the Criteria, and the number, size, and physical configuration of any...

  18. 40 CFR 221.1 - Applications for permits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... Applications for general, special, emergency, and research permits under section 102 of the Act may be filed... equipment; (c) Adequate physical and chemical description of material to be dumped, including results of tests necessary to apply the Criteria, and the number, size, and physical configuration of any...

  19. 40 CFR 221.1 - Applications for permits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... for general, special, emergency, and research permits under section 102 of the Act may be filed with... equipment; (c) Adequate physical and chemical description of material to be dumped, including results of tests necessary to apply the Criteria, and the number, size, and physical configuration of any...

  20. 40 CFR 221.1 - Applications for permits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... Applications for general, special, emergency, and research permits under section 102 of the Act may be filed... equipment; (c) Adequate physical and chemical description of material to be dumped, including results of tests necessary to apply the Criteria, and the number, size, and physical configuration of any...

  1. 40 CFR 221.1 - Applications for permits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... Applications for general, special, emergency, and research permits under section 102 of the Act may be filed... equipment; (c) Adequate physical and chemical description of material to be dumped, including results of tests necessary to apply the Criteria, and the number, size, and physical configuration of any...

  2. Parental and Peer Factors Associated with Body Image Discrepancy among Fifth-Grade Boys and Girls

    PubMed Central

    Wentzel, Kathryn; Elliott, Marc N.; Dittus, Patricia J.; Kanouse, David E.; Wallander, Jan L.; Pasch, Keryn E.; Franzini, Luisa; Taylor, Wendell C.; Qureshi, Tariq; Franklin, Frank A.; Schuster, Mark A.

    2015-01-01

    Many young adolescents are dissatisfied with their body due to a discrepancy between their ideal and actual body size, which can lead to weight cycling, eating disorders, depression, and obesity. The current study examined the associations of parental and peer factors with fifth-graders’ body image discrepancy, physical self-worth as a mediator between parental and peer factors and body image discrepancy, and how these associations vary by child’s sex. Body image discrepancy was defined as the difference between young adolescents’ self-perceived body size and the size they believe a person their age should be. Data for this study came from Healthy Passages, which surveyed 5,147 fifth graders (51 % females; 34 % African American, 35 % Latino, 24 % White, and 6 % other) and their primary caregivers from the United States. Path analyses were conducted separately for boys and girls. The findings for boys suggest father nurturance and getting along with peers are related negatively to body image discrepancy; however, for girls, fear of negative evaluation by peers is related positively to body image discrepancy. For both boys and girls, getting along with peers and fear of negative evaluation by peers are related directly to physical self-worth. In addition, mother nurturance is related positively to physical self-worth for girls, and father nurturance is related positively to physical self-worth for boys. In turn, physical self-worth, for both boys and girls, is related negatively to body image discrepancy. The findings highlight the potential of parental and peer factors to reduce fifth graders’ body image discrepancy. PMID:23334988

  3. Cognitive fatigue effects on physical performance: A systematic review and meta-analysis.

    PubMed

    McMorris, Terry; Barwood, Martin; Hale, Beverley J; Dicks, Matt; Corbett, Jo

    2018-05-01

    Recent research has examined the effect that undertaking a cognitively fatiguing task for ≤90 min has on subsequent physical performance. Cognitive fatigue is claimed to affect subsequent physical performance by inducing energy depletion in the brain, depletion of brain catecholamine neurotransmitters or changes in motivation. Observation of the psychophysiology and neurochemistry literature questions the ability of 90 min' cognitive activity to deplete energy or catecholamine resources. The purpose of this study, therefore, was to examine the evidence for cognitive fatigue having an effect on subsequent physical performance. A systematic, meta-analytic review was undertaken. We found a small but significant pooled effect size based on comparison between physical performance post-cognitive fatigue compared to post-control (g = -0.27, SE = -0.12, 95% CI -0.49 to -0.04, Z(10) = -2.283, p < 0.05). However, the results were not heterogenous (Q(10) = 2.789, p > 0.10, Τ 2  < 0.001), suggesting that the pooled effect size does not amount to a real effect and differences are due to random error. No publication bias was evident (Kendall's τ = -0.07, p > 0.05). Thus, the results are somewhat contradictory. The pooled effect size shows a small but significant negative effect of cognitive fatigue, however tests of heterogeneity show that the results are due to random error. Future research should use neuroscientific tests to ensure that cognitive fatigue has been achieved. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. Nesting environment may drive variation in eggshell structure and egg characteristics in the Testudinata.

    PubMed

    Deeming, D Charles

    2018-05-14

    Testudines exhibit considerable variation in the degree of eggshell calcification, which affects eggshell conductance, water physiology of the embryos, and calcium metabolism of embryos. However, the underlying reason for different shell types has not been explored. Phylogenetically controlled analyses examined relationships between egg size, shell mass, and clutch size in ∼200 turtle species from a range of body sizes and assigned by family as laying either rigid- or pliable-shelled eggs. Shell type affected egg breadth relative to pelvic dimensions, egg mass, and relative shell mass but did not affect size, mass, or total shell mass of the clutch. These results suggest that calcium availability may be a function of body size and the type of shell may reflect in part the interplay between clutch size and egg size. It was further concluded that the eggshell probably evolved as a means of physical protection. Differences in shell calcification may not primarily reflect reproductive parameters but rather correlate with the acidity of a species' nesting environment. Low pH environments may have thicker calcareous layer to counteract the erosion caused by the soil and maintain the integrity of the physical barrier. Limited calcium availability may constrain clutch size. More neutral nesting substrates expose eggshells to less erosion so calcification per egg can be reduced and this allows larger clutch sizes. This pattern is also reflected in thick, calcified crocodilian eggs. Further research is needed to test whether eggshell calcification in the testudines correlates with nest pH in order to verify this relationship. © 2018 Wiley Periodicals, Inc.

  5. Brood size and its importance for nestling growth in the Biscutate Swift (Streptoprocne biscutata, Aves: Apodidae).

    PubMed

    Pichorim, M; Monteiro-Filho, E L A

    2008-11-01

    Many Apodidae, including Streptoprocne biscutata (Sclater, 1866), drop eggs from their nests during incubation. This is interpreted as nest site competition or accident. We provide evidence that egg ejection is deliberate and that this behaviour controls the brood size. Brood sizes were manipulated and nestling growth was measured to test the hypothesis that pairs can regulate brood size during incubation based on current ability to rear nestlings. Natural (control) broods with one, two and three nestlings, and manipulated (experimental) broods reduced to one and increased to two and three young were monitored. Growth rates were measured based on weight, and wing, tail and tarsus lengths of natural and manipulated broods. We compared the slopes of each measure's regression lines of the nestlings of each brood size by t-test. Nestling growth of control nests was similar and relatively little associated with brood size. In broods reduced to one nestling, weight, wing and tail had greater growth rates, and in broods increased to three nestlings growth rates were lower. Weight was most, and tarsus length least influenced by brood size. In general, nestling growth of manipulated nests was inversely proportional to brood size. The results suggest that pairs with larger clutches are in better physical conditions than others. Thus, in experimental broods, pairs are over or under-loaded because feeding activities increase or decrease and these changes affect the growth rate of the nestlings. The present study suggests that egg ejection can control brood size. This behaviour is probably stimulated by physical changes in the adult birds during incubation.

  6. Statistical Analyses of Satellite Cloud Object Data from CERES. Part III; Comparison with Cloud-Resolving Model Simulations of Tropical Convective Clouds

    NASA Technical Reports Server (NTRS)

    Luo, Yali; Xu, Kuan-Man; Wielicki, Bruce A.; Wong, Takmeng; Eitzen, Zachary A.

    2007-01-01

    The present study evaluates the ability of a cloud-resolving model (CRM) to simulate the physical properties of tropical deep convective cloud objects identified from a Clouds and the Earth s Radiant Energy System (CERES) data product. The emphasis of this study is the comparisons among the small-, medium- and large-size categories of cloud objects observed during March 1998 and between the large-size categories of cloud objects observed during March 1998 (strong El Ni o) and March 2000 (weak La Ni a). Results from the CRM simulations are analyzed in a way that is consistent with the CERES retrieval algorithm and they are averaged to match the scale of the CERES satellite footprints. Cloud physical properties are analyzed in terms of their summary histograms for each category. It is found that there is a general agreement in the overall shapes of all cloud physical properties between the simulated and observed distributions. Each cloud physical property produced by the CRM also exhibits different degrees of disagreement with observations over different ranges of the property. The simulated cloud tops are generally too high and cloud top temperatures are too low except for the large-size category of March 1998. The probability densities of the simulated top-of-the-atmosphere (TOA) albedos for all four categories are underestimated for high albedos, while those of cloud optical depth are overestimated at its lowest bin. These disagreements are mainly related to uncertainties in the cloud microphysics parameterization and inputs such as cloud ice effective size to the radiation calculation. Summary histograms of cloud optical depth and TOA albedo from the CRM simulations of the large-size category of cloud objects do not differ significantly between the March 1998 and 2000 periods, consistent with the CERES observations. However, the CRM is unable to reproduce the significant differences in the observed cloud top height while it overestimates the differences in the observed outgoing longwave radiation and cloud top temperature between the two periods. Comparisons between the CRM results and the observations for most parameters in March 1998 consistently show that both the simulations and observations have larger differences between the large- and small-size categories than between the large- and medium-size, or between the medium- and small-size categories. However, the simulated cloud properties do not change as much with size as observed. These disagreements are likely related to the spatial averaging of the forcing data and the mismatch in time and in space between the numerical weather prediction model from which the forcing data are produced and the CERES observed cloud systems.

  7. THE SIZE AND SURFACE COATING OF NANOSILVER DIFFERENTIALLY AFFECTS BIOLOGICAL ACTIVITY IN BLOOD BRAIN BARRIER (RBEC4) CELLS.

    EPA Science Inventory

    Linking the physical properties of nanoparticles with differences in their biological activity is critical for understanding their potential toxicity and mode of action. The influence of aggregate size, surface coating, and surface charge on nanosilver's (nanoAg) movement through...

  8. Mixed-Up Messages: Ambiguities in Newspaper Representations of the Young Child.

    ERIC Educational Resources Information Center

    Jackson, Ian

    1995-01-01

    Reports a six-year study of explicit references to young children's small physical stature in an Australian newspaper. Suggests that when newspaper representations of children and childhood are examined for their focus on children's diminutive size, two conflicting themes emerge: endearment versus depreciation. Suggests that these size-value…

  9. Are Arabic and Verbal Numbers Processed in Different Ways?

    ERIC Educational Resources Information Center

    Kadosh, Roi Cohen; Henik, Avishai; Rubinsten, Orly

    2008-01-01

    Four experiments were conducted in order to examine effects of notation--Arabic and verbal numbers--on relevant and irrelevant numerical processing. In Experiment 1, notation interacted with the numerical distance effect, and irrelevant physical size affected numerical processing (i.e., size congruity effect) for both notations but to a lesser…

  10. Techniques for determining partial size distribution of particulate matter: Laser diffraction versus electrical sensing zone

    USDA-ARS?s Scientific Manuscript database

    The study of health impacts, emission estimation of particulate matter (PM), and development of new control technologies require knowledge of PM characteristics. Among these PM characteristics, the particle size distribution (PSD) is perhaps the most important physical parameter governing particle b...

  11. Techniques for measuring particle size distribution of particulate matter emitted from animal feeding operations

    USDA-ARS?s Scientific Manuscript database

    Particle size distribution (PSD) is perhaps the most important physical parameter governing the airborne particle behavior. Various methods and techniques are available for conducting PSD analyses. Unfortunately, there is no single agreed upon method to determine the PSDs of particulate matter (PM) ...

  12. Discrete element method as an approach to model the wheat milling process

    USDA-ARS?s Scientific Manuscript database

    It is a well-known phenomenon that break-release, particle size, and size distribution of wheat milling are functions of machine operational parameters and grain properties. Due to the non-uniformity of characteristics and properties of wheat kernels, the kernel physical and mechanical properties af...

  13. Small size transformer provides high power regulation with low ripple and maximum control

    NASA Technical Reports Server (NTRS)

    Manoli, R.; Ulrich, B. R.

    1971-01-01

    Single, variable, transformer/choke device does work of several. Technique reduces drawer assembly physical size and design and manufacturing cost. Device provides power, voltage current and impedance regulation while maintaining maximum control of linearity and ensuring extremely low ripple. Nulling is controlled to very fine degree.

  14. Pictorial depth probed through relative sizes

    PubMed Central

    Wagemans, Johan; van Doorn, Andrea J; Koenderink, Jan J

    2011-01-01

    In the physical environment familiar size is an effective depth cue because the distance from the eye to an object equals the ratio of its physical size to its angular extent in the visual field. Such simple geometrical relations do not apply to pictorial space, since the eye itself is not in pictorial space, and consequently the notion “distance from the eye” is meaningless. Nevertheless, relative size in the picture plane is often used by visual artists to suggest depth differences. The depth domain has no natural origin, nor a natural unit; thus only ratios of depth differences could have an invariant significance. We investigate whether the pictorial relative size cue yields coherent depth structures in pictorial spaces. Specifically, we measure the depth differences for all pairs of points in a 20-point configuration in pictorial space, and we account for these observations through 19 independent parameters (the depths of the points modulo an arbitrary offset), with no meaningful residuals. We discuss a simple formal framework that allows one to handle individual differences. We also compare the depth scale obtained by way of this method with depth scales obtained in totally different ways, finding generally good agreement. PMID:23145258

  15. Lunar Dust Characterization Activity at GRC

    NASA Technical Reports Server (NTRS)

    Street, Kenneth W.

    2008-01-01

    The fidelity of lunar simulants as compared to actual regolith is evaluated using Figures of Merit (FOM) which are based on four criteria: Particle Size, Particle Shape, Composition, and Density of the bulk material. In practice, equipment testing will require other information about both the physical properties (mainly of the dust fraction) and composition as a function of particle size. At Glenn Research Center (GRC) we are involved in evaluating a number of simulant properties of consequence to testing of lunar equipment in a relevant environment, in order to meet Technology Readiness Level (TRL) 6 criteria. Bulk regolith has been characterized for many decades, but surprisingly little work has been done on the dust fraction (particles less than 20 micrometers in diameter). GRC is currently addressing the information shortfall by characterizing the following physical properties: Particle Size Distribution, Adhesion, Abrasivity, Surface Energy, Magnetic Susceptibility, Tribocharging and Surface Chemistry/Reactivity. Since some of these properties are also dependent on the size of the particles we have undertaken the construction of a six stage axial cyclone particle separator to fractionate dust into discrete particle size distributions for subsequent evaluation of these properties. An introduction to this work and progress to date will be presented.

  16. The Influence of Physical and Social Contexts of Eating on Lunch-Time Food Intake among Southern Ontario, Canada, Middle School Students

    ERIC Educational Resources Information Center

    Woodruff, Sarah J.; Hanning, Rhona M.; McGoldrick, Kathryn

    2010-01-01

    Background: Among students, little is known about the physical and social context of eating lunch. The objective of this study was to determine if food intake (including the type of food and beverages and portion sizes) was associated with specific aspects of the physical and social lunch environment (location, with whom lunch was consumed, who…

  17. Economic Analysis of Physical Activity Interventions

    PubMed Central

    Wu, Shinyi; Cohen, Deborah; Shi, Yuyan; Pearson, Marjorie; Sturm, Roland

    2011-01-01

    Background Numerous interventions have been shown to increase physical activity, but have not been ranked by effectiveness or cost. Purpose This study provides a systematic review of physical activity interventions and calculates their cost-effectiveness ratios. Methods A systematic literature review was conducted (5,579 articles) and 91 effective interventions promoting physical activity were identified with enough information to translate effects into MET-hours gained. Cost-effectiveness ratios were then calculated as cost per MET-hour gained per day per individual reached. Physical activity benefits were compared to U.S. guideline–recommended levels (1.5 MET-hours per day for adults and 3.0 MET-hours per day for children, equivalent to walking 30 and 60 minutes respectively). Results The most cost-effective strategies were for point-of-decision prompts (e.g., signs to prompt stair use), with a median cost of $0.07/MET-hour/day/person; these had tiny effects, adding only 0.2% of minimum recommended physical activity levels. School-based physical activity interventions targeting children and adolescents ranked well with a median of $0.42/MET-hour/day/person, generating an average of 16% of recommended physical activity. Although there were few interventions in the categories of “creation or enhanced access to places for physical activity” and “community campaigns”, several were cost effective. The least cost-effective categories were the high-intensity “individually-adapted behavior change” and “social support” programs; with median CE ratios of $0.84/ and $1.16/MET-hour/day/person. However, they also had the largest effect sizes, adding 35%–43% of recommended physical activity, respectively. Study quality was variable, with many relying on self-reported outcomes. Conclusions The cost-effectiveness, effect size, and study quality should all be considered when choosing physical activity interventions. PMID:21238863

  18. Ballistic heat transport in laser generated nano-bubbles

    NASA Astrophysics Data System (ADS)

    Lombard, Julien; Biben, Thierry; Merabia, Samy

    2016-08-01

    Nanobubbles generated by laser heated plasmonic nanoparticles are of interest for biomedical and energy harvesting applications. Of utmost importance is the maximal size of these transient bubbles. Here, we report hydrodynamic phase field simulations of the dynamics of laser induced nanobubbles, with the aim to understand which physical processes govern their maximal size. We show that the nanobubble maximal size and lifetime are to a large extent controlled by the ballistic thermal flux which is present inside the bubble. Taking into account this thermal flux, we can reproduce the fluence dependence of the maximal nanobubble radius as reported experimentally. We also discuss the influence of the laser pulse duration on the number of nanobubbles generated and their maximal size. These studies represent a significant step toward the optimization of the nanobubble size, which is of crucial importance for photothermal cancer therapy applications.Nanobubbles generated by laser heated plasmonic nanoparticles are of interest for biomedical and energy harvesting applications. Of utmost importance is the maximal size of these transient bubbles. Here, we report hydrodynamic phase field simulations of the dynamics of laser induced nanobubbles, with the aim to understand which physical processes govern their maximal size. We show that the nanobubble maximal size and lifetime are to a large extent controlled by the ballistic thermal flux which is present inside the bubble. Taking into account this thermal flux, we can reproduce the fluence dependence of the maximal nanobubble radius as reported experimentally. We also discuss the influence of the laser pulse duration on the number of nanobubbles generated and their maximal size. These studies represent a significant step toward the optimization of the nanobubble size, which is of crucial importance for photothermal cancer therapy applications. Electronic supplementary information (ESI) available. See DOI: 10.1039/C6NR02144A

  19. Evaluating Suit Fit Using Performance Degradation

    NASA Technical Reports Server (NTRS)

    Margerum, Sarah E.; Cowley, Matthew; Harvill, Lauren; Benson, Elizabeth; Rajulu, Sudhakar

    2011-01-01

    The Mark III suit has multiple sizes of suit components (arm, leg, and gloves) as well as sizing inserts to tailor the fit of the suit to an individual. This study sought to determine a way to identify the point an ideal suit fit transforms into a bad fit and how to quantify this breakdown using mobility-based physical performance data. This study examined the changes in human physical performance via degradation of the elbow and wrist range of motion of the planetary suit prototype (Mark III) with respect to changes in sizing and as well as how to apply that knowledge to suit sizing options and improvements in suit fit. The methods implemented in this study focused on changes in elbow and wrist mobility due to incremental suit sizing modifications. This incremental sizing was within a range that included both optimum and poor fit. Suited range of motion data was collected using a motion analysis system for nine isolated and functional tasks encompassing the elbow and wrist joints. A total of four subjects were tested with motions involving both arms simultaneously as well as the right arm only. The results were then compared across sizing configurations. The results of this study indicate that range of motion may be used as a viable parameter to quantify at what stage suit sizing causes a detriment in performance; however the human performance decrement appeared to be based on the interaction of multiple joints along a limb, not a single joint angle. The study was able to identify a preliminary method to quantify the impact of size on performance and to develop a means to gauge tolerances around optimal size. More work is needed to improve the assessment of optimal fit and to compensate for multiple joint interactions.

  20. Environmental influences on the evolution of body size in Ammonoids

    NASA Astrophysics Data System (ADS)

    Hines, S.; Khong, C.; Pelagio, M.; Seixas, G.; Payne, J.

    2012-12-01

    A major debate in evolutionary biology and paleobiology focuses on the relative importance of ecological interactions between species versus changes in the physical environment in governing large-scale evolutionary patterns. Body size is among the most important traits of any organism, and so identifying the factors that influence size evolution can shed light on both the causes and consequences of many major evolutionary trends. However, the extent to which body size evolution over time can be explained by changes in the physical versus ecological context remains unknown. In this study, we examined body size evolution in ammonoids, an extinct group of marine cephalopods. We collected a representative body size for each genus from illustrated specimens in the Treatise on Invertebrate Paleontology. We then examined relative statistical support for six models of size evolution: random walk, directional trend, stasis, and environmental control by oxygen availability, temperature, and global sea level. No model is unambiguously supported over all others. Unbiased random walk was the best supported model (34%) and environmental control by atmospheric pO2 was the second best supported model (22%). Stasis received the least support (<<1%). Because we find pO2 to be inversely correlated with ammonoid size, we suspect that the observed correlation does not reflect a direct causal relationship. Overall, our results suggest that no single, simple model can be used to characterize the evolution of ammonoid size over the entire history of this clade. We speculate that controls on ammonoid size evolution varied through geological time, both due to long-term shifts in the ecological structure of marine communities and short-term perturbations associated with major extinction events.

  1. Exploring metrics to express energy expenditure of physical activity in youth

    USDA-ARS?s Scientific Manuscript database

    Several approaches have been used to express energy expenditure in youth, but no consensus exists as to which best normalizes data for the wide range of ages and body sizes across a range of physical activities. This study examined several common metrics for expressing energy expenditure to determin...

  2. Does Stevens's Power Law for Brightness Extend to Perceptual Brightness Averaging?

    ERIC Educational Resources Information Center

    Bauer, Ben

    2009-01-01

    Stevens's power law ([Psi][infinity][Phi][beta]) captures the relationship between physical ([Phi]) and perceived ([Psi]) magnitude for many stimulus continua (e.g., luminance and brightness, weight and heaviness, area and size). The exponent ([beta]) indicates whether perceptual magnitude grows more slowly than physical magnitude ([beta] less…

  3. 21 CFR 111.20 - What design and construction requirements apply to your physical plant?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... surfaces, with microorganisms, chemicals, filth, or other extraneous material. Your physical plant must have, and you must use, separate or defined areas of adequate size or other control systems, such as computerized inventory controls or automated systems of separation, to prevent contamination and mixups of...

  4. 21 CFR 111.20 - What design and construction requirements apply to your physical plant?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... surfaces, with microorganisms, chemicals, filth, or other extraneous material. Your physical plant must have, and you must use, separate or defined areas of adequate size or other control systems, such as computerized inventory controls or automated systems of separation, to prevent contamination and mixups of...

  5. 76 FR 13647 - Proposed Collection; Comment Request-Interactive Diet and Activity Tracking in AARP (iDATA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... be submitted to the Office of Management and Budget (OMB) for review and approval. Proposed... size to evaluate the measurement error structure of the diet and physical activity assessment... on cancer research, diagnosis, prevention and treatment. Dietary and physical activity data will be...

  6. The Role of Interest in Physical Education: A Review of Research Evidence

    ERIC Educational Resources Information Center

    Chen, Ang; Wang, Yubing

    2017-01-01

    This article focuses on the research on interest, especially situational interest, in physical education. Interest has been considered a powerful motivator for children and adolescents. Based on a conceptualization of individual and situational interest, a reasonable size of evidence has been accumulated showing that situational interest motivates…

  7. Gender-Specific Associations between Personality Traits, Physical Activity, and Body Size Dissatisfaction

    ERIC Educational Resources Information Center

    Lodewyk, Ken; Sullivan, Philip

    2017-01-01

    A recently validated trait personality framework is the HEXACO (honesty-humility, emotionality, extraversion, agreeableness, conscientiousness, and openness to experience). Little is yet known about how the HEXACO personality dimensions and its subsets--particularly the dimension of honesty-humility--relates to physical activity and body size…

  8. Differently Designed Playgrounds and Preschooler's Physical Activity Play

    ERIC Educational Resources Information Center

    Luchs, Antje; Fikus, Monika

    2018-01-01

    New playground concepts--favouring natural play characteristics--emerge. The aim of our free play study is to explore the relation between newly established natural playgrounds and the widely spread contemporary ones in terms of physical activity levels. The playground features differ in vegetation, topography, size and play equipment. The…

  9. Systems Models for Transportation Problems : Part 2. The Social Physics for Modern Societies - the Role of the Cities

    DOT National Transportation Integrated Search

    1977-09-01

    The objective of the research was to make use of a physically based social systems model, developed earlier, to study the determinants of city sizes and their national interactions. In particular, information on the role of a transportation system in...

  10. Physical properties of peats as related to degree of decomposition

    Treesearch

    D.H. Boelter

    1969-01-01

    Important physical characteristics, such as water retention, water yield coefficient, and hydraulic conductivity, vary greatly for representative northern Minnesota peat materials. The differences are related to the degree of decomposition, which largely determines the porosity and pore size distribution. Fiber content (> 0.1 mm) and bulk density are properties...

  11. Contextualized Magnetism in Secondary School: Learning from the LHC (CERN)

    ERIC Educational Resources Information Center

    Cid, Ramon

    2005-01-01

    Physics teachers in secondary schools usually mention the world's largest particle physics laboratory--CERN (European Organization for Nuclear Research)--only because of the enormous size of the accelerators and detectors used there, the number of scientists involved in their activities and also the necessary international scientific…

  12. a Latent Variable Path Analysis Model of Secondary Physics Enrollments in New York State.

    NASA Astrophysics Data System (ADS)

    Sobolewski, Stanley John

    The Percentage of Enrollment in Physics (PEP) at the secondary level nationally has been approximately 20% for the past few decades. For a more scientifically literate citizenry as well as specialists to continue scientific research and development, it is desirable that more students enroll in physics. Some of the predictor variables for physics enrollment and physics achievement that have been identified previously includes a community's socioeconomic status, the availability of physics, the sex of the student, the curriculum, as well as teacher and student data. This study isolated and identified predictor variables for PEP of secondary schools in New York. Data gathered by the State Education Department for the 1990-1991 school year was used. The source of this data included surveys completed by teachers and administrators on student characteristics and school facilities. A data analysis similar to that done by Bryant (1974) was conducted to determine if the relationships between a set of predictor variables related to physics enrollment had changed in the past 20 years. Variables which were isolated included: community, facilities, teacher experience, number of type of science courses, school size and school science facilities. When these variables were isolated, latent variable path diagrams were proposed and verified by the Linear Structural Relations computer modeling program (LISREL). These diagrams differed from those developed by Bryant in that there were more manifest variables used which included achievement scores in the form of Regents exam results. Two criterion variables were used, percentage of students enrolled in physics (PEP) and percent of students enrolled passing the Regents physics exam (PPP). The first model treated school and community level variables as exogenous while the second model treated only the community level variables as exogenous. The goodness of fit indices for the models was 0.77 for the first model and 0.83 for the second model. No dramatic differences were found between the relationship of predictor variables to physics enrollment in 1972 and 1991. New models indicated that smaller school size, enrollment in previous science and math courses and other school variables were more related to high enrollment rather than achievement. Exogenous variables such as community size were related to achievement. It was shown that achievement and enrollment were related to a different set of predictor variables.

  13. Techniques for Measuring Liquid Water Content Along a Trajectory

    DTIC Science & Technology

    1981-03-12

    a problem in the small snow or ice crystal regions. When particle sizes ex- ceed the range of the instrument, the spectral distribution is... distribution will remain relatively constant beyond the physical size limitatiom Therefore. the trend of the distribution should be established from...diaMeri in- milimoeter. he marmum particle size (D) has previously been found- e..i."----U to be related to the s.ove of the distribution by an expression

  14. High Performance Nuclear Magnetic Resonance Imaging Using Magnetic Resonance Force Microscopy

    DTIC Science & Technology

    2013-12-12

    Micron- Size Ferromagnet . Physical Review Letters, 92(3) 037205 (2004) [22] A. Z. Genack and A. G. Redeld. Theory of nuclear spin diusion in a...perform spatially resolved scanned probe studies of spin dynamics in nanoscale ensembles of few electron spins of varying size . Our research culminated...perform spatially resolved scanned probe studies of spin dynamics in nanoscale ensembles of few electron spins of varying size . Our research culminated

  15. A novel clinical evaluation method using maximum angular velocity during knee extension to assess lower extremity muscle function of older adults.

    PubMed

    Arai, Takeshi; Obuchi, Shuichi; Shiba, Yoshitaka

    2017-11-01

    The purpose of this study is to examine the utilities of maximum angular velocity (AV) assessment during knee extension (KE) using a gyroscope for clinical evaluation of exercise program for older adults. Two hundred and 4 community-dwelling older adults underwent a 3-month exercise intervention program. Outcome measures included AV during KE and other physical functions (isometric strength (IS), walking abilities, and balance functions). A correlation coefficient was used to evaluate the relationships between AV and other physical functions at baseline. The differences of physical functions before and after intervention were evaluated and the effect size of each measurement was calculated after the program. The AV measurement was significantly correlated with IS during KE (r=0.303, P<0.01) and other physical functions. Most correlation coefficients of angular velocity were greater than that of IS. All of physical assessments were significantly improved. Also, effect size of AV was greater than that of IS (d=0.45 vs. 0.42). AV of the lower extremities is useful to evaluate the effects of exercise intervention in the elderly. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Geoacoustic provinces and physical properties of surface sediments in the southern part of the East Sea, Korea

    NASA Astrophysics Data System (ADS)

    Kim, Sora; Bahk, Jang-Jun; Kim, Daechoul; Lee, Gwang Soo; Kim, Seong-Pil

    2017-04-01

    A total of 288 piston and box core samples were collected and analyzed to characterize the physical properties and geoacoustic provinces of surficial sediments in the southern part of the East Sea. Based on in-situ condition sound velocity (converted laboratory sound velocity to in-situ condition sound velocity) and sediment properties (sediment textures and physical properties), the study area was divided into eight provinces (Province IA, IB, IC, II, III, IV, VA, and VB) : (1) Province IA : hemi-pelagic mud partially mixed with intermittent sandy sediments originating from the outer shelf due to slide/slump or mass flows (in-situ condition sound velocity: 1439 m/s, mean grain size: 8.5Φ, bulk density: 1.24 g/cm3,and porosity: 84%); (2) Province IB : Holocene muddy sediments are dominant, but in some area that is influenced by the surrounding land and coast (in-situ condition sound velocity: 1448 m/s, mean grain size: 8.3Φ, bulk density: 1.32 g/cm3, and porosity: 79%); (3) Province IC : muddy sediments that were deposited during the Holocene (in-situ condition sound velocity: 1457 m/s, mean grain size: 7.8Φ, bulk density: 1.36 g/cm3, and porosity: 78%); (4) Province II : mixed recent and relict sediments (in-situ condition sound velocity: 1493 m/s, mean grain size: 5.9Φ, bulk density: 1.53 g/cm3, and porosity: 68%); (5) Province III (Pohang) : there is a mixture of muddy sediments and sandy sediments and sediments from Hyeongsan River are mostly deposited (in-situ condition sound velocity: 1586 m/s, mean grain size: 4.1Φ, bulk density: 1.74 g/cm3, and porosity: 57%); (6) Province IV : coarse-grained relict sediments formed during the Pleistocene (in-situ condition sound velocity: 1572 m/s, mean grain size: 4.1Φ, bulk density: 1.76 g/cm3, and porosity: 55%); (7) Province VA : relict sand with some gravel, show marked differences from the area in which muddy sediments are deposited (in-situ condition sound velocity: 1662 m/s, mean grain size: 3.3Φ, bulk density: 1.82 g/cm3, and porosity: 51%), and (8) Province VB : similar to but coarser sediments than Province IV (in-situ condition sound velocity: 1667 m/s, mean grain size: 3.2Φ, bulk density: 1.87 g/cm3, and porosity: 46%). The in-situ condition sound velocity, mean grain size, and bulk density increased from Province IA to Province VB, whereas the porosity and water content decrease. Variability of the physical and acoustic properties tended to follow the general of the mean grain size. The classification of each province using the in-situ condition sound velocity corrected with the temperature and sediment type provides a better reflection of the sediment properties and sedimentary environment.

  17. Economies of scale: The physics basis

    NASA Astrophysics Data System (ADS)

    Bejan, A.; Almerbati, A.; Lorente, S.

    2017-01-01

    Why is size so important? Why are "economies of scale" a universal feature of all flow systems, animate, inanimate, and human made? The empirical evidence is clear: the bigger are more efficient carriers (per unit) than the smaller. This natural tendency is observed across the board, from animal design to technology, logistics, and economics. In this paper, we rely on physics (thermodynamics) to determine the relation between the efficiency and size. Here, the objective is to predict a natural phenomenon, which is universal. It is not to model a particular type of device. The objective is to demonstrate based on physics that the efficiencies of diverse power plants should increase with size. The analysis is performed in two ways. First is the tradeoff between the "external" irreversibilities due to the temperature differences that exist above and below the temperature range occupied by the circuit executed by the working fluid. Second is the allocation of the fluid flow irreversibility between the hot and cold portions of the fluid flow circuit. The implications of this report in economics and design science (scaling up, scaling down) and the necessity of multi-scale design with hierarchy are discussed.

  18. Highlights from the functional single nucleotide polymorphisms associated with human muscle size and strength or FAMuSS study.

    PubMed

    Pescatello, Linda S; Devaney, Joseph M; Hubal, Monica J; Thompson, Paul D; Hoffman, Eric P

    2013-01-01

    The purpose of the Functional Single Nucleotide Polymorphisms Associated with Human Muscle Size and Strength study or FAMuSS was to identify genetic factors that dictated the response of health-related fitness phenotypes to resistance exercise training (RT). The phenotypes examined were baseline muscle strength and muscle, fat, and bone volume and their response to RT. FAMuSS participants were 1300 young (24 years), healthy men (42%) and women (58%) that were primarily of European-American descent. They were genotyped for ~500 polymorphisms and completed the Paffenbarger Physical Activity Questionnaire to assess energy expenditure and time spent in light, moderate, and vigorous intensity habitual physical activity and sitting. Subjects then performed a 12-week progressive, unilateral RT program of the nondominant arm with the dominant arm used as a comparison. Before and after RT, muscle strength was measured with the maximum voluntary contraction and one repetition maximum, while MRI measured muscle, fat, and bone volume. We will discuss the history of how FAMuSS originated, provide a brief overview of the FAMuSS methods, and summarize our major findings regarding genotype associations with muscle strength and size, body composition, cardiometabolic biomarkers, and physical activity.

  19. Highlights from the Functional Single Nucleotide Polymorphisms Associated with Human Muscle Size and Strength or FAMuSS Study

    PubMed Central

    Pescatello, Linda S.; Devaney, Joseph M.; Hubal, Monica J.; Thompson, Paul D.; Hoffman, Eric P.

    2013-01-01

    The purpose of the Functional Single Nucleotide Polymorphisms Associated with Human Muscle Size and Strength study or FAMuSS was to identify genetic factors that dictated the response of health-related fitness phenotypes to resistance exercise training (RT). The phenotypes examined were baseline muscle strength and muscle, fat, and bone volume and their response to RT. FAMuSS participants were 1300 young (24 years), healthy men (42%) and women (58%) that were primarily of European-American descent. They were genotyped for ~500 polymorphisms and completed the Paffenbarger Physical Activity Questionnaire to assess energy expenditure and time spent in light, moderate, and vigorous intensity habitual physical activity and sitting. Subjects then performed a 12-week progressive, unilateral RT program of the nondominant arm with the dominant arm used as a comparison. Before and after RT, muscle strength was measured with the maximum voluntary contraction and one repetition maximum, while MRI measured muscle, fat, and bone volume. We will discuss the history of how FAMuSS originated, provide a brief overview of the FAMuSS methods, and summarize our major findings regarding genotype associations with muscle strength and size, body composition, cardiometabolic biomarkers, and physical activity. PMID:24455711

  20. Rheological and physical parameters correlations in formulations with pinhão derivatives stability study: building up an analytical route.

    PubMed

    Moschini Daudt, Renata; Medeiros Cardozo, Nilo Sergio; Damasceno Ferreira Marczak, Ligia; Clemes Külkamp Guerreiro, Irene

    2018-07-01

    This study focuses on the correlation investigation between rheological and physical parameters and how it can contribute to optimize the topical formulations development. A gel and an emulgel containing pinhão derivatives, and their respective controls, were analyzed along six months of storage. A flowchart of analyses was proposed to use in topical formulation development when a benchmark is the goal or when it is necessary to change some raw material. All formulations were stable over the storage time and the formulations containing pinhão starch and coat extract presented similar properties to those of the control formulations. Correlations between rheological and physical data, as moisture content and particle size, were determined using Pearson's correlation coefficient. A moderate positive correlation was verified between particle size distribution and flow index, and a strong positive correlation between particle size and flow index. It was also found that the higher the moisture content, the higher the consistency index, quality factor, and apparent viscosity. The correlation analyses applied in this study contributed to build up an analytical route for topical formulation development, saving time and costs.

  1. Promoting gross motor skills and physical activity in childcare: A translational randomized controlled trial.

    PubMed

    Jones, Rachel A; Okely, Anthony D; Hinkley, Trina; Batterham, Marijka; Burke, Claire

    2016-09-01

    Educator-led programs for physical activity and motor skill development show potential but few have been implemented and evaluated using a randomized controlled design. Furthermore, few educator-led programs have evaluated both gross motor skills and physical activity. Therefore, the aim of this study was to evaluate a gross motor skill and physical activity program for preschool children which was facilitated solely by childcare educators. A six-month 2-arm randomized controlled trial was implemented between April and September 2012 in four early childhood centers in Tasmania, Australia. Educators participated in ongoing professional development sessions and children participated in structured physical activity lessons and unstructured physical activity sessions. In total, 150 children were recruited from four centers which were randomized to intervention or wait-list control group. Six early childhood educators from the intervention centers were trained to deliver the intervention. Gross motor skills were assessed using the Test of Gross Motor Development (2nd edition) and physical activity was measured objectively using GT3X+ Actigraph accelerometers. No statistically significant differences were identified. However, small to medium effect sizes, in favor of the intervention group, were evident for four of the five gross motor skills and the total gross motor skill score and small to medium effect sizes were reported for all physical activity outcomes. This study highlights the potential of educator-led physical activity interventions and supports the need for further translational trials within the early childhood sector. Copyright © 2015 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  2. Organization and scaling in water supply networks

    NASA Astrophysics Data System (ADS)

    Cheng, Likwan; Karney, Bryan W.

    2017-12-01

    Public water supply is one of the society's most vital resources and most costly infrastructures. Traditional concepts of these networks capture their engineering identity as isolated, deterministic hydraulic units, but overlook their physics identity as related entities in a probabilistic, geographic ensemble, characterized by size organization and property scaling. Although discoveries of allometric scaling in natural supply networks (organisms and rivers) raised the prospect for similar findings in anthropogenic supplies, so far such a finding has not been reported in public water or related civic resource supplies. Examining an empirical ensemble of large number and wide size range, we show that water supply networks possess self-organized size abundance and theory-explained allometric scaling in spatial, infrastructural, and resource- and emission-flow properties. These discoveries establish scaling physics for water supply networks and may lead to novel applications in resource- and jurisdiction-scale water governance.

  3. First complete chromosomal organization of a protozoan plant parasite (Phytomonas spp.).

    PubMed

    Marín, Clotilde; Alberge, Blandine; Dollet, Michel; Pagès, Michel; Bastien, Patrick

    2008-01-01

    Phytomonas spp. are members of the family Trypanosomatidae that parasitize plants and may cause lethal diseases in crops such as Coffee Phloem necrosis, Hartrot in coconut, and Marchitez sorpresiva in oil palm. In this study, the molecular karyotype of 6 isolates from latex plants has been entirely elucidated by pulsed-field gel electrophoresis and DNA hybridization. Twenty-one chromosomal linkage groups constituting heterologous chromosomes and sizing between 0.3 and 3 Mb could be physically defined by the use of 75 DNA markers (sequence-tagged sites and genes). From these data, the genome size can be estimated at 25.5 (+/-2) Mb. The physical linkage groups were consistently conserved in all strains examined. Moreover, the finding of several pairs of different-sized homologous chromosomes strongly suggest diploidy for this organism. The definition of the complete molecular karyotype of Phytomonas represents an essential primary step toward sequencing the genome of this parasite of economical importance.

  4. Preference of redear sunfish on zebra mussels and rams-horn snails

    USGS Publications Warehouse

    French, John R. P.; Morgan, Michael N.

    1995-01-01

    We tested prey preferences of adult (200- to 222-mm long) redear sunfish (Lepomis microlophus) on two size classes of zebra mussels (Dreissena polymorpha) and two-ridge rams-horns (Helisoma anceps) in experimental aquaria. We also tested physical limitations on consuming these mollusks and determined prey bioenergetic profitability. Redear sunfish strongly preferred rams-horns over zebra mussels, but they displayed no size preference for either prey. Ingestion was not physically limited since both prey species up to 15-mm long fit within the pharyngeal gapes of redear sunfish. Rams-horns were more bioenergetically profitable than zebra mussels and ingestion of rams-horn shell fragments was about three times less than zebra mussels. Rams-horns were somewhat more resistant to shell-crushing, but all size ranges of both prey species tested were crushable by redear sunfish. These studies suggested that the redear sunfish should not be considered a panacea for biological control of zebra mussels.

  5. Scalable Super-Resolution Synthesis of Core-Vest Composites Assisted by Surface Plasmons.

    PubMed

    Montazeri, A O; Kim, Y; Fang, Y S; Soheilinia, N; Zaghi, G; Clark, J K; Maboudian, R; Kherani, N P; Carraro, C

    2018-02-15

    The behavior of composite nanostructures depends on both size and elemental composition. Accordingly, concurrent control of size, shape, and composition of nanoparticles is key to tuning their functionality. In typical core-shell nanoparticles, the high degree of symmetry during shell formation results in fully encapsulated cores with severed access to the surroundings. We commingle light parameters (wavelength, intensity, and pulse duration) with the physical properties of nanoparticles (size, shape, and composition) to form hitherto unrealized core-vest composite nanostructures (CVNs). Unlike typical core-shells, the plasmonic core of the resulting CVNs selectively maintains physical access to its surrounding. Tunable variations in local temperature profiles ≳50 °C are plasmonically induced over starburst-shaped nanoparticles as small as 50-100 nm. These temperature variations result in CVNs where the shell coverage mirrors the temperature variations. The precision thus offered individually tailors access pathways of the core and the shell.

  6. Adsorption of diclofenac and nimesulide on activated carbon: Statistical physics modeling and effect of adsorbate size

    NASA Astrophysics Data System (ADS)

    Sellaoui, Lotfi; Mechi, Nesrine; Lima, Éder Cláudio; Dotto, Guilherme Luiz; Ben Lamine, Abdelmottaleb

    2017-10-01

    Based on statistical physics elements, the equilibrium adsorption of diclofenac (DFC) and nimesulide (NM) on activated carbon was analyzed by a multilayer model with saturation. The paper aimed to describe experimentally and theoretically the adsorption process and study the effect of adsorbate size using the model parameters. From numerical simulation, the number of molecules per site showed that the adsorbate molecules (DFC and NM) were mostly anchored in both sides of the pore walls. The receptor sites density increase suggested that additional sites appeared during the process, to participate in DFC and NM adsorption. The description of the adsorption energy behavior indicated that the process was physisorption. Finally, by a model parameters correlation, the size effect of the adsorbate was deduced indicating that the molecule dimension has a negligible effect on the DFC and NM adsorption.

  7. Sintering mantle mineral aggregates with submicron grains: examples of olivine and clinopyroxene

    NASA Astrophysics Data System (ADS)

    Tsubokawa, Y.; Ishikawa, M.

    2017-12-01

    Physical property of the major mantle minerals play an important role in the dynamic behavior of the Earth's mantle. Recently, it has been found that nano- to sub-micron scale frictional processes might control faulting processes and earthquake instability, and ultrafine-grained mineral aggregates thus have attracted the growing interest. Here we investigated a method for preparing polycrystalline clinoyproxene and polycrystalline olivine with grain size of sub-micron scale from natural crystals, two main constituents of the upper mantle. Nano-sized powders of both minerals are sintered under argon flow at temperatures ranging from 1130-1350 °C for 0.5-20 h. After sintering at 1180 °C and 1300 °C, we successfully fabricated polycrystalline clinopyroxene and polycrystalline olivine with grain size of < 500 nm, respectively. Our experiments demonstrate future measurements of ultrafine-grained mineral aggregates on its physical properties of Earth's mantle.

  8. The Physics of Protoplanetary Dust Agglomerates. X. High-velocity Collisions between Small and Large Dust Agglomerates as a Growth Barrier

    NASA Astrophysics Data System (ADS)

    Schräpler, Rainer; Blum, Jürgen; Krijt, Sebastiaan; Raabe, Jan-Hendrik

    2018-01-01

    In a protoplanetary disk, dust aggregates in the μm to mm size range possess mean collision velocities of 10–60 m s‑1 with respect to dm- to m-sized bodies. We performed laboratory collision experiments to explore this parameter regime and found a size- and velocity-dependent threshold between erosion and growth. By using a local Monte Carlo coagulation calculation and along with a simple semi-analytical timescale approach, we show that erosion considerably limits particle growth in protoplanetary disks and leads to a steady-state dust-size distribution from μm- to dm-sized particles.

  9. The physical impacts of microplastics on marine organisms: a review.

    PubMed

    Wright, Stephanie L; Thompson, Richard C; Galloway, Tamara S

    2013-07-01

    Plastic debris at the micro-, and potentially also the nano-scale, are widespread in the environment. Microplastics have accumulated in oceans and sediments worldwide in recent years, with maximum concentrations reaching 100 000 particles m(3). Due to their small size, microplastics may be ingested by low trophic fauna, with uncertain consequences for the health of the organism. This review focuses on marine invertebrates and their susceptibility to the physical impacts of microplastic uptake. Some of the main points discussed are (1) an evaluation of the factors contributing to the bioavailability of microplastics including size and density; (2) an assessment of the relative susceptibility of different feeding guilds; (3) an overview of the factors most likely to influence the physical impacts of microplastics such as accumulation and translocation; and (4) the trophic transfer of microplastics. These findings are important in guiding future marine litter research and management strategies. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Distant Comets in the Early Solar System

    NASA Technical Reports Server (NTRS)

    Meech, Karen J.

    2000-01-01

    The main goal of this project is to physically characterize the small outer solar system bodies. An understanding of the dynamics and physical properties of the outer solar system small bodies is currently one of planetary science's highest priorities. The measurement of the size distributions of these bodies will help constrain the early mass of the outer solar system as well as lead to an understanding of the collisional and accretional processes. A study of the physical properties of the small outer solar system bodies in comparison with comets in the inner solar system and in the Kuiper Belt will give us information about the nebular volatile distribution and small body surface processing. We will increase the database of comet nucleus sizes making it statistically meaningful (for both Short-Period and Centaur comets) to compare with those of the Trans-Neptunian Objects. In addition, we are proposing to do active ground-based observations in preparation for several upcoming space missions.

  11. Improving nutrition and physical activity in the workplace: a meta-analysis of intervention studies.

    PubMed

    Hutchinson, Amanda D; Wilson, Carlene

    2012-06-01

    A comprehensive search of the literature for studies examining physical activity or nutrition interventions in the workplace, published between 1999 and March 2009, was conducted. This search identified 29 relevant studies. Interventions were grouped according to the theoretical framework on which the interventions were based (e.g. education, cognitive-behavioural, motivation enhancement, social influence, exercise). Weighted Cohen's d effect sizes, percentage overlap statistics, confidence intervals and fail safe Ns were calculated. Most theoretical approaches were associated with small effects. However, large effects were found for some measures of interventions using motivation enhancement. Effect sizes were larger for studies focusing on one health behaviour and for randomized controlled trials. The workplace is a suitable environment for making modest changes in the physical activity, nutrition and health of employees. Further research is necessary to determine whether these changes can be maintained in the long term.

  12. Requirements for fault-tolerant factoring on an atom-optics quantum computer.

    PubMed

    Devitt, Simon J; Stephens, Ashley M; Munro, William J; Nemoto, Kae

    2013-01-01

    Quantum information processing and its associated technologies have reached a pivotal stage in their development, with many experiments having established the basic building blocks. Moving forward, the challenge is to scale up to larger machines capable of performing computational tasks not possible today. This raises questions that need to be urgently addressed, such as what resources these machines will consume and how large will they be. Here we estimate the resources required to execute Shor's factoring algorithm on an atom-optics quantum computer architecture. We determine the runtime and size of the computer as a function of the problem size and physical error rate. Our results suggest that once the physical error rate is low enough to allow quantum error correction, optimization to reduce resources and increase performance will come mostly from integrating algorithms and circuits within the error correction environment, rather than from improving the physical hardware.

  13. Outcome regimes of binary raindrop collisions

    NASA Astrophysics Data System (ADS)

    Testik, Firat Y.

    2009-11-01

    This study delineates the physical conditions that are responsible for the occurrence of main outcome regimes (i.e., bounce, coalescence, and breakup) for binary drop collisions with a precipitation microphysics perspective. Physical considerations based on the collision kinetic energy and the surface energies of the colliding drops lead to the development of a theoretical regime diagram for the drop/raindrop collision outcomes in the We- p plane ( We — Weber number, p — raindrop diameter ratio). This theoretical regime diagram is supported by laboratory experimental observations of drop collisions using high-speed imaging. Results of this fundamental study bring in new insights into the quantitative understanding of drop dynamics, applications of which extend beyond precipitation microphysics. In particular, results of this drop collision study are expected to give impetus to the physics-based dynamic modeling of the drop size distributions that is essential for various typical modern engineering applications, including numerical modeling of evolution of raindrop size distribution in rain shaft.

  14. Manipulation of particles by weak forces

    NASA Technical Reports Server (NTRS)

    Adler, M. S.; Savkar, S. D.; Summerhayes, H. R.

    1972-01-01

    Quantitative relations between various force fields and their effects on the motion of particles of various sizes and physical characteristics were studied. The forces considered were those derived from light, heat, microwaves, electric interactions, magnetic interactions, particulate interactions, and sound. A physical understanding is given of the forces considered as well as formulae which express how the size of the force depends on the physical and electrical properties of the particle. The drift velocity in a viscous fluid is evaluated as a function of initial acceleration and the effects of thermal random motion are considered. A means of selectively sorting or moving particles by choosing a force system and/or environment such that the particle of interest reacts uniquely was developed. The forces considered and a demonstration of how the initial acceleration, drift velocity, and ultimate particle density distribution is affected by particle, input, and environmental parameters are tabulated.

  15. Changes in the physical and mechanical properties of Al-Mg alloy processed by severe plastic deformation

    NASA Astrophysics Data System (ADS)

    Krasnoveikin, V. A.; Kozulin, A. A.; Skripnyak, V. A.; Moskvichev, E. N.; Borodulin, D. A.

    2017-12-01

    This paper presents the results of studies into the effect of severe plastic deformation on the microstructure, physical and mechanical properties of coarse-grained Al-Mg alloy 1560 in the as-received state with an average grain size of 50 µm. Severe plastic deformation is performed by four-pass equal channel angular pressing (ECAP), which results in the formation of an ultrafine-grained structure with an average grain size of 3 µm in the alloy. Analysis of experimental data revealed that the physical and mechanical properties change significantly after severe plastic deformation. The microhardness of the ECAPed alloy increases by 50%, tensile yield strength by 80%, and ultimate strength by 44% in comparison with these parameters in the as-received state. The constants of approximating functions have been determined for the experimental stress-strain curves of the alloy specimens in the as-received and ECAPed states.

  16. U.S. Air Force Research Laboratory's Need for Flow Physics and Control With Applications Involving Aero-Optics and Weapon Bay Cavities

    NASA Technical Reports Server (NTRS)

    Schmit, Ryan

    2010-01-01

    To develop New Flow Control Techniques: a) Knowledge of the Flow Physics with and without control. b) How does Flow Control Effect Flow Physics (What Works to Optimize the Design?). c) Energy or Work Efficiency of the Control Technique (Cost - Risk - Benefit Analysis). d) Supportability, e.g. (size of equipment, computational power, power supply) (Allows Designer to include Flow Control in Plans).

  17. Development of the Instructional Model of Reading English Strategies for Enhancing Sophomore Students' Learning Achievements in the Institute of Physical Education in the Northeastern Region of Thailand

    ERIC Educational Resources Information Center

    Whankhom, Prawit; Phusawisot, Pilanut; Sayankena, Patcharanon

    2016-01-01

    The aim of this research is to develop and verify the effectiveness of an instructional model of reading English strategies for students of Mahasarakham Institute of Physical Education in the Northeastern region through survey. Classroom action research techniques with the two groups of sample sizes of 34 sophomore physical students as a control…

  18. Physical fitness differences between prepubescent boys and girls.

    PubMed

    Marta, Carlos C; Marinho, Daniel A; Barbosa, Tiago M; Izquierdo, Mikel; Marques, Mário C

    2012-07-01

    The purpose of this study was to analyze in which physical capabilities boys and girls are closer or distant. An additional objective was to find which of the body fat, physical activity, and somatotype factors have a greater effect on prepubescent children's physical fitness. This was a cross-sectional study involving 312 children (10.8 ± 0.4 years). The physical fitness assessment employed sets of aerobic fitness, strength, flexibility, speed, agility, and balance. The boys presented higher values in all selected tests, except tests of balance and flexibility, in which girls scored better. Gender differences in the physical fitness were greatest in the explosive strength of upper (p ≤ 0.01, η(p)(2) = 0.09) and lower limbs (p ≤ 0.01, η(p)(2) = 0.08), although with a medium-size effect of gender, and smaller in the abdominal (p > 0.05, η(p)(2) = 0.007) and upper limbs (p > 0.05, η(p)(2) = 0.003) muscular endurance, and trunk extensor strength and flexibility (p > 0.05, η(p)(2) = 0.001). The endomorphic (p ≤ 0.01, η(p)(2) = 0.26) in the girls, and the ectomorphic (p ≤ 0.01, η(p)(2) = 0.31) and mesomorphic (p ≤ 0.01, η(p)(2) = 0.26) in the boys, had the high-sized effect on the physical fitness. The physical activity in the girls, and the endomorphic and body fat in the boys, did not have a significant effect. These findings can help in the planning of activities that take into account the success and motivation of both boys and girls and thus increase levels of physical activity and physical fitness at school. However, in prepubescent children, one cannot neglect the influence of genetic determinism, observed from the morphoconstitutional point of view.

  19. Assessing the specific energy consumption and physical properties of comminuted Douglas-fir chips for bioconversion

    Treesearch

    Yalan Liu; Jinwu Wang; Michael P. Wolcott

    2016-01-01

    Size reduction homogenizes the bulk biomass and facilitates downstream feedstock handling, transportation, and storage. Effects of feeding rate, mill-type (hammer and knife mill), screen size, and moisture content on comminution energy consumption of commercial Douglas-fir (Pseudotsuga menziesii) pulp chips were quantified. The resulting particles...

  20. Of Huge Mice and Tiny Elephants: Exploring the Relationship Between Inhibitory Processes and Preschool Math Skills

    PubMed Central

    Merkley, Rebecca; Thompson, Jodie; Scerif, Gaia

    2016-01-01

    The cognitive mechanisms underpinning the well-established relationship between inhibitory control and early maths skills remain unclear. We hypothesized that a specific aspect of inhibitory control drives its association with distinct math skills in very young children: the ability to ignore stimulus dimensions that are in conflict with task-relevant representations. We used an Animal Size Stroop task in which 3- to 6-year-olds were required to ignore the physical size of animal pictures to compare their real-life dimensions. In Experiment 1 (N = 58), performance on this task correlated with standardized early mathematics achievement. In Experiment 2 (N = 48), performance on the Animal Size Stroop task related to the accuracy of magnitude comparison, specifically for trials on which the physical size of dot arrays was incongruent with their numerosity. This highlights a process-oriented relationship between interference control and resolving conflict between discrete and continuous quantity, and in turn calls for further detailed empirical investigations of whether, how and why inhibitory processes matter to emerging numerical cognition. PMID:26779057

  1. Of Huge Mice and Tiny Elephants: Exploring the Relationship Between Inhibitory Processes and Preschool Math Skills.

    PubMed

    Merkley, Rebecca; Thompson, Jodie; Scerif, Gaia

    2015-01-01

    The cognitive mechanisms underpinning the well-established relationship between inhibitory control and early maths skills remain unclear. We hypothesized that a specific aspect of inhibitory control drives its association with distinct math skills in very young children: the ability to ignore stimulus dimensions that are in conflict with task-relevant representations. We used an Animal Size Stroop task in which 3- to 6-year-olds were required to ignore the physical size of animal pictures to compare their real-life dimensions. In Experiment 1 (N = 58), performance on this task correlated with standardized early mathematics achievement. In Experiment 2 (N = 48), performance on the Animal Size Stroop task related to the accuracy of magnitude comparison, specifically for trials on which the physical size of dot arrays was incongruent with their numerosity. This highlights a process-oriented relationship between interference control and resolving conflict between discrete and continuous quantity, and in turn calls for further detailed empirical investigations of whether, how and why inhibitory processes matter to emerging numerical cognition.

  2. Autophagy selectivity through receptor clustering

    NASA Astrophysics Data System (ADS)

    Rutenberg, Andrew; Brown, Aidan

    Substrate selectivity in autophagy requires an all-or-none cellular response. We focus on peroxisomes, for which autophagy receptor proteins NBR1 and p62 are well characterized. Using computational models, we explore the hypothesis that physical clustering of autophagy receptor proteins on the peroxisome surface provides an appropriate all-or-none response. We find that larger peroxisomes nucleate NBR1 clusters first, and lose them due to competitive coarsening last, resulting in significant size-selectivity. We then consider a secondary hypothesis that p62 inhibits NBR1 cluster formation. We find that p62 inhibition enhances size-selectivity enough that, even if there is no change of the pexophagy rate, the volume of remaining peroxisomes can significantly decrease. We find that enhanced ubiquitin levels suppress size-selectivity, and that this effect is more pronounced for individual peroxisomes. Sufficient ubiquitin allows receptor clusters to form on even the smallest peroxisomes. We conclude that NBR1 cluster formation provides a viable physical mechanism for all-or-none substrate selectivity in pexophagy. We predict that cluster formation is associated with significant size-selectivity. Now at Simon Fraser University.

  3. Operator Localization of Virtual Objects

    NASA Technical Reports Server (NTRS)

    Ellis, Stephen R.; Menges, Brian M.; Null, Cynthia H. (Technical Monitor)

    1998-01-01

    Errors in the localization of nearby virtual objects presented via see-through, helmet mounted displays are examined as a function of viewing conditions and scene content. Monocular, biocular or stereoscopic presentation of the virtual objects, accommodation (required focus), subjects'age, and the position of physical surfaces are examined. Nearby physical surfaces are found to introduce localization errors that differ depending upon the other experimental factors. The apparent physical size and transparency of the virtual objects and physical surfaces respectively are also influenced by their relative position when superimposed. Design implications are discussed.

  4. Physical approaches to biomaterial design

    PubMed Central

    Mitragotri, Samir; Lahann, Joerg

    2009-01-01

    The development of biomaterials for drug delivery, tissue engineering and medical diagnostics has traditionally been based on new chemistries. However, there is growing recognition that the physical as well as the chemical properties of materials can regulate biological responses. Here, we review this transition with regard to selected physical properties including size, shape, mechanical properties, surface texture and compartmentalization. In each case, we present examples demonstrating the significance of these properties in biology. We also discuss synthesis methods and biological applications for designer biomaterials, which offer unique physical properties. PMID:19096389

  5. Perception while watching movies: Effects of physical screen size and scene type.

    PubMed

    Troscianko, Tom; Meese, Timothy S; Hinde, Stephen

    2012-01-01

    Over the last decade, television screens and display monitors have increased in size considerably, but has this improved our televisual experience? Our working hypothesis was that the audiences adopt a general strategy that "bigger is better." However, as our visual perceptions do not tap directly into basic retinal image properties such as retinal image size (C. A. Burbeck, 1987), we wondered whether object size itself might be an important factor. To test this, we needed a task that would tap into the subjective experiences of participants watching a movie on different-sized displays with the same retinal subtense. Our participants used a line bisection task to self-report their level of "presence" (i.e., their involvement with the movie) at several target locations that were probed in a 45-min section of the movie "The Good, The Bad, and The Ugly." Measures of pupil dilation and reaction time to the probes were also obtained. In Experiment 1, we found that subjective ratings of presence increased with physical screen size, supporting our hypothesis. Face scenes also produced higher presence scores than landscape scenes for both screen sizes. In Experiment 2, reaction time and pupil dilation results showed the same trends as the presence ratings and pupil dilation correlated with presence ratings, providing some validation of the method. Overall, the results suggest that real-time measures of subjective presence might be a valuable tool for measuring audience experience for different types of (i) display and (ii) audiovisual material.

  6. 4D Imaging of Salt Precipitation during Evaporation from Saline Porous Media Influenced by the Particle Size Distribution

    NASA Astrophysics Data System (ADS)

    Norouzi Rad, M.; Shokri, N.

    2014-12-01

    Understanding the physics of water evaporation from saline porous media is important in many processes such as evaporation from porous media, vegetation, plant growth, biodiversity in soil, and durability of building materials. To investigate the effect of particle size distribution on the dynamics of salt precipitation in saline porous media during evaporation, we applied X-ray micro-tomography technique. Six samples of quartz sand with different grain size distributions were used in the present study enabling us to constrain the effects of particle and pore sizes on salt precipitation patterns and dynamics. The pore size distributions were computed using the pore-scale X-ray images. The packed beds were saturated with NaCl solution of 3 Molal and the X-ray imaging was continued for one day with temporal resolution of 30 min resulting in pore scale information about the evaporation and precipitation dynamics. Our results show more precipitation at the early stage of the evaporation in the case of sand with the larger particle size due to the presence of fewer evaporation sites at the surface. The presence of more preferential evaporation sites at the surface of finer sands significantly modified the patterns and thickness of the salt crust deposited on the surface such that a thinner salt crust was formed in the case of sand with smaller particle size covering larger area at the surface as opposed to the thicker patchy crusts in samples with larger particle sizes. Our results provide new insights regarding the physics of salt precipitation in porous media during evaporation.

  7. Formulation and shelf life stability of water-borne lecithin nanoparticles for potential application in dietary supplements field.

    PubMed

    Edris, Amr E

    2012-09-01

    ABSTRACT The objective of the present investigation is to formulate commercial soybean lecithin as nanoparticles in solvent-free aqueous system for potential supplementary applications. A mechanical method, which involved two major steps, was used for that purpose. First, lecithin submicron particles (~ 0.5 μm) have been prepared by gradual hydration of lecithin powder using mechanical agitation. Finally, the size of these particles was further reduced to < 100 nm by using high-pressure microfluidization. The physical stability (appearance, particle size distribution, ζ-potential) and the chemical stability (lipid oxidation) of the dispersions carrying lecithin nanoparticles were assessed every 15 days during the 3-month shelf life period at two different temperatures. Results showed that the final particle size of lecithin in the freshly prepared aqueous dispersion was 79.8 ± 1.0 nm and the amount of peroxide detected was 3.5 ± 0.2 meq/kg lipid. At the end of the storage period, dispersions stored at 4°C exhibited physical and chemical stability as evident from the translucent appearance, the small change in particle size (84.1 ± 1.3 nm), and the small amount of generated peroxides (4.1 ± 0.2 meq/kg lipid). On the other hand, dispersions stored at 25°C were physically stable up to 60 days. Over that period, samples became turbid and the particle size increased to 145.0 ± 1.7 nm with a bimodal distribution pattern. This behavior was due to phospholipids (PLs) degradation and hydrolysis under acidic conditions, which proceeds faster at a relatively high temperature (25°C) than at (4°C). The outcome of this investigation may help in developing water-based dispersions carrying lecithin nanoparticles for dietary supplement of PLs.

  8. Measurements of Photoelectric Yield and Physical Properties of Individual Lunar Dust Grains

    NASA Technical Reports Server (NTRS)

    Abbas, M. M.; Tankosic, D.; Craven, P. D.; Spann, J. F.; LeClair, A.; West, F. A.; Taylor, L.; Hoover, R.

    2005-01-01

    Micron size dust grains levitated and transported on the lunar surface constitute a major problem for the robotic and human habitat missions for the Moon. It is well known since the Apollo missions that the lunar surface is covered with a thick layer of micron/sub-micron size dust grains. Transient dust clouds over the lunar horizon were observed by experiments during the Apollo 17 mission. Theoretical models suggest that the dust grains on the lunar surface are charged by the solar UV radiation as well as the solar wind. Even without any physical activity, the dust grains are levitated by electrostatic fields and transported away from the surface in the near vacuum environment of the Moon. The current dust charging and the levitation models, however, do not fully explain the observed phenomena. Since the abundance of dust on the Moon's surface with its observed adhesive characteristics is believed to have a severe impact on the human habitat and the lifetime and operations of a variety of equipment, it is necessary to investigate the phenomena and the charging properties of the lunar dust in order to develop appropriate mitigating strategies. We will present results of some recent laboratory experiments on individual micro/sub-micron size dust grains levitated in electrodynamic balance in simulated space environments. The experiments involve photoelectric emission measurements of individual micron size lunar dust grains illuminated with UV radiation in the 120-160 nm wavelength range. The photoelectric yields are required to determine the charging properties of lunar dust illuminated by solar UV radiation. We will present some recent results of laboratory measurement of the photoelectric yields and the physical properties of individual micron size dust grains from the Apollo and Luna-24 sample returns as well as the JSC-1 lunar simulants.

  9. Microcystin distribution in physical size class separations of natural plankton communities

    USGS Publications Warehouse

    Graham, J.L.; Jones, J.R.

    2007-01-01

    Phytoplankton communities in 30 northern Missouri and Iowa lakes were physically separated into 5 size classes (>100 ??m, 53-100 ??m, 35-53 ??m, 10-35 ??m, 1-10 ??m) during 15-21 August 2004 to determine the distribution of microcystin (MC) in size fractionated lake samples and assess how net collections influence estimates of MC concentration. MC was detected in whole water (total) from 83% of takes sampled, and total MC values ranged from 0.1-7.0 ??g/L (mean = 0.8 ??g/L). On average, MC in the > 100 ??m size class comprised ???40% of total MC, while other individual size classes contributed 9-20% to total MC. MC values decreased with size class and were significantly greater in the >100 ??m size class (mean = 0.5 ??g /L) than the 35-53 ??m (mean = 0.1 ??g/L), 10-35 ??m (mean = 0.0 ??g/L), and 1-10 ??m (mean = 0.0 ??g/L) size classes (p < 0.01). MC values in nets with 100-??m, 53-??m, 35-??m, and 10-??m mesh were cumulatively summed to simulate the potential bias of measuring MC with various size plankton nets. On average, a 100-??m net underestimated total MC by 51%, compared to 37% for a 53-??m net, 28% for a 35-??m net, and 17% for a 10-??m net. While plankton nets consistently underestimated total MC, concentration of algae with net sieves allowed detection of MC at low levels (???0.01 ??/L); 93% of lakes had detectable levels of MC in concentrated samples. Thus, small mesh plankton nets are an option for documenting MC occurrence, but whole water samples should be collected to characterize total MC concentrations. ?? Copyright by the North American Lake Management Society 2007.

  10. THE EFFECT OF PROJECTION ON DERIVED MASS-SIZE AND LINEWIDTH-SIZE RELATIONSHIPS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shetty, Rahul; Kauffmann, Jens; Goodman, Alyssa A.

    2010-04-01

    Power-law mass-size and linewidth-size correlations, two of 'Larson's laws', are often studied to assess the dynamical state of clumps within molecular clouds. Using the result of a hydrodynamic simulation of a molecular cloud, we investigate how geometric projection may affect the derived Larson relationships. We find that large-scale structures in the column density map have similar masses and sizes to those in the three-dimensional simulation (position-position-position, PPP). Smaller scale clumps in the column density map are measured to be more massive than the PPP clumps, due to the projection of all emitting gas along lines of sight. Further, due tomore » projection effects, structures in a synthetic spectral observation (position-position-velocity, PPV) may not necessarily correlate with physical structures in the simulation. In considering the turbulent velocities only, the linewidth-size relationship in the PPV cube is appreciably different from that measured from the simulation. Including thermal pressure in the simulated line widths imposes a minimum line width, which results in a better agreement in the slopes of the linewidth-size relationships, though there are still discrepancies in the offsets, as well as considerable scatter. Employing commonly used assumptions in a virial analysis, we find similarities in the computed virial parameters of the structures in the PPV and PPP cubes. However, due to the discrepancies in the linewidth-size and mass-size relationships in the PPP and PPV cubes, we caution that applying a virial analysis to observed clouds may be misleading due to geometric projection effects. We speculate that consideration of physical processes beyond kinetic and gravitational pressure would be required for accurately assessing whether complex clouds, such as those with highly filamentary structure, are bound.« less

  11. Electromagnetic density of modes for a finite-size three-dimensional structure.

    PubMed

    D'Aguanno, Giuseppe; Mattiucci, Nadia; Centini, Marco; Scalora, Michael; Bloemer, Mark J

    2004-05-01

    The concept of the density of modes has been lacking a precise mathematical definition for a finite-size structure. With the explosive growth in the fabrication of photonic crystals and nanostructures, which are inherently finite in size, a workable definition is imperative. We give a simple and physically intuitive definition of the electromagnetic density of modes based on the Green's function for a generic three-dimensional open cavity filled with a linear, isotropic, dielectric material.

  12. Experimental Study of the Possibility to Make a Mortar with Ternary Sand (Natural and Artificial Fine Aggregates)

    NASA Astrophysics Data System (ADS)

    Baali, L.; Naceri, A.; Rahmouni, Z.; Mehidi, M. W. Noui

    This experimental study investigates the possibility to make a mortar with a ternary sand (natural and artificial fine aggregates). This method is utilized to correct the particle size distribution of various sands used in mortar. For this investigation, three sands have been used: a dune sand (DS), a slag sand (SS), and brick sand (BS) at different proportions in mortar. After crushing, the artificial fine aggregate (blast furnace slag and waste brick fine aggregate) was sifted in order to use it as fine aggregate. The effect of the quality and grain size distribution of natural fine aggregate (i.e., DS) and artificial fine aggregates (i.e., SS and BS) on the physical properties of ternary sand confected (density, porosity, fineness modulus, equivalent sand, particle size distribution, water absorption) and properties of fresh and hardened mortar were analysed. In the same way for this study, the physical properties and chemical compositions of DS, SS, BS and cement were investigated. The results obtained show that the mechanical strength on mortar depends of the nature and particle size distribution of sand studied. The reuse of this recycled material (slag blast furnace and waste brick) in the industry would contribute to the protection of the environment. This study shows the potential of this method to make mortar with ternary sand (natural and artificial fine aggreagates) in order to improve the physical properties of sand. Utilising natural and artificial fine aggregates to produce quality mortar should yield significant environmental benefits.

  13. Resolving the Origin of Pseudo-Single Domain Magnetic Behavior

    NASA Astrophysics Data System (ADS)

    Roberts, Andrew P.; Almeida, Trevor P.; Church, Nathan S.; Harrison, Richard J.; Heslop, David; Li, Yiliang; Li, Jinhua; Muxworthy, Adrian R.; Williams, Wyn; Zhao, Xiang

    2017-12-01

    The term "pseudo-single domain" (PSD) has been used to describe the transitional state in rock magnetism that spans the particle size range between the single domain (SD) and multidomain (MD) states. The particle size range for the stable SD state in the most commonly occurring terrestrial magnetic mineral, magnetite, is so narrow ( 20-75 nm) that it is widely considered that much of the paleomagnetic record of interest is carried by PSD rather than stable SD particles. The PSD concept has, thus, become the dominant explanation for the magnetization associated with a major fraction of particles that record paleomagnetic signals throughout geological time. In this paper, we argue that in contrast to the SD and MD states, the term PSD does not describe the relevant physical processes, which have been documented extensively using three-dimensional micromagnetic modeling and by parallel research in material science and solid-state physics. We also argue that features attributed to PSD behavior can be explained by nucleation of a single magnetic vortex immediately above the maximum stable SD transition size. With increasing particle size, multiple vortices, antivortices, and domain walls can nucleate, which produce variable cancellation of magnetic moments and a gradual transition into the MD state. Thus, while the term PSD describes a well-known transitional state, it fails to describe adequately the physics of the relevant processes. We recommend that use of this term should be discontinued in favor of "vortex state," which spans a range of behaviors associated with magnetic vortices.

  14. Adolescent Obesity Prevention in Botswana: Beliefs and Recommendations of School Personnel

    ERIC Educational Resources Information Center

    Shaibu, Sheila; Holsten, Joanna E.; Stettler, Nicolas; Maruapula, Segametsi D.; Jackson, Jose C.; Malete, Leapetswe; Mokone, George; Wrotniak, Brian H.; Compher, Charlene W.

    2012-01-01

    The study's objectives were to gain school personnel's (1) perceptions on diet, physical activity, body size, and obesity, (2) description of school food and physical activity practices, and (3) recommendations for programs to prevent adolescent obesity. The study took place in six junior secondary schools of varying socioeconomic status in…

  15. Sensitivity to Verbally and Physically Harassing Behaviors and Reported Incidents in Junior High/Middle School Students.

    ERIC Educational Resources Information Center

    Turner, Penelope B.

    This thesis investigates the sensitivity of junior high/middle school students to statements depicting verbal and physical sexual harassment. The independent variables that were investigated included gender, grade level, age, size of district, grades received, participation in sports, birth order, developmental level, and self-esteem. Students…

  16. Easy Implementation of Internet-Based Whiteboard Physics Tutorials

    ERIC Educational Resources Information Center

    Robinson, Andrew

    2008-01-01

    The requirement for a method of capturing problem solving on a whiteboard for later replay stems from my teaching load, which includes two classes of first-year university general physics, each with relatively large class sizes of approximately 80-100 students. Most university-level teachers value one-to-one interaction with the students and find…

  17. Physical Foundations for Socio-Economic Modeling for Transportation Planning : Part 1. Interaction Between Urban Centers as a Potential Process.

    DOT National Transportation Integrated Search

    1977-09-01

    The objective of this research is to make use of a physically based social system model to study the determinants of city sizes and their interactions in a nation. In particular, it was required that attention be paid to how new transportation system...

  18. Vacuum Energy and Inflation: 1. A Liter of Vacuum Energy

    ERIC Educational Resources Information Center

    Huggins, Elisha

    2013-01-01

    In the popular press, diagrams showing the evolution of the universe begin with a great jump in size labeled "inflation." Can we explain the basic ideas behind inflation to our students who have taken our introductory physics course? Probably not. In our standard introductory physics courses, even those with special relativity, something…

  19. An Assessment of Research-Doctorate Programs in the United States: Mathematical & Physical Sciences.

    ERIC Educational Resources Information Center

    Jones, Lyle V., Ed.; And Others

    The quality of doctoral-level chemistry (N=145), computer science (N=58), geoscience (N=91), mathematics (N=115), physics (N=123), and statistics/biostatistics (N=64) programs at United States universities was assessed, using 16 measures. These measures focused on variables related to: program size; characteristics of graduates; reputational…

  20. Assessment of mild steel damage characteristics by physical methods

    NASA Astrophysics Data System (ADS)

    Botvina, L. R.; Soldatenkov, A. P.; Levin, V. P.; Tyutin, M. R.; Demina, Yu. A.; Petersen, T. B.; Dubov, A. A.; Semashko, N. A.

    2016-01-01

    The deformation and fracture localization characteristics are estimated by the methods of replicas, acoustic emission, metal magnetic memory, ultrasonic attenuation, microhardness, and electrical resistance. The relation between the estimated physical parameters on the one hand and the plastic zone size and the microcrack concentration in this zone, on the other, is considered.

  1. Grinding energy and physical properties of chopped and hammer-milled barley, wheat, oat, and canola straws

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J.S. Tumuluru; L.G. Tabil; Y. Song

    2014-01-01

    In the present study, specific energy for grinding and physical properties of wheat, canola, oat and barley straw grinds were investigated. The initial moisture content of the straw was about 0.13–0.15 (fraction total mass basis). Particle size reduction experiments were conducted in two stages: (1) a chopper without a screen, and (2) a hammer mill using three screen sizes (19.05, 25.4, and 31.75 mm). The lowest grinding energy (1.96 and 2.91 kWh t-1) was recorded for canola straw using a chopper and hammer mill with 19.05-mm screen size, whereas the highest (3.15 and 8.05 kWh t-1) was recorded for barleymore » and oat straws. The physical properties (geometric mean particle diameter, bulk, tapped and particle density, and porosity) of the chopped and hammer-milled wheat, barley, canola, and oat straw grinds measured were in the range of 0.98–4.22 mm, 36–80 kg m-3, 49–119 kg m-3, 600–1220 kg m-3, and 0.9–0.96, respectively. The average mean particle diameter was highest for the chopped wheat straw (4.22-mm) and lowest for the canola grind (0.98-mm). The canola grinds produced using the hammer mill (19.05-mm screen size) had the highest bulk and tapped density of about 80 and 119 kg m-3; whereas, the wheat and oat grinds had the lowest of about 58 and 88–90 kg m-3. The results indicate that the bulk and tapped densities are inversely proportional to the particle size of the grinds. The flow properties of the grinds calculated are better for chopped straws compared to hammer milled using smaller screen size (19.05 mm).« less

  2. POM Pulses: Characterizing the Physical and Chemical Properties of Particulate Organic Matter (POM) Mobilized by Large Storm Events and its Influence on Receiving Fluvial Systems

    NASA Astrophysics Data System (ADS)

    Johnson, E. R.; Rowland, R. D.; Protokowicz, J.; Inamdar, S. P.; Kan, J.; Vargas, R.

    2016-12-01

    Extreme storm events have tremendous erosive energy which is capable of mobilizing vast amounts of material from watershed sources into fluvial systems. This complex mixture of sediment and particulate organic matter (POM) is a nutrient source, and has the potential to impact downstream water quality. The impact of POM on receiving aquatic systems can vary not only by the total amount exported but also by the various sources involved and the particle sizes of POM. This study examines the composition of POM in potential sources and within-event POM by: (1) determining the amount and quality of dissolved organic matter (DOM) that can be leached from coarse, medium and fine particle classes; (2) assessing the C and N content and isotopic character of within-event POM; and (3) coupling physical and chemical properties to evaluate storm event POM influence on stream water. Storm event POM samples and source sediments were collected from a forested headwater catchment (second order stream) in the Piedmont region of Maryland. Samples were sieved into three particle classes - coarse (2mm-1mm), medium (1mm-250µm) and fine (<250µm). Extractions were performed for three particle class sizes and the resulting fluorescent organic matter was analyzed. Carbon (C) and Nitrogen (N) amount, C:N ratio, and isotopic analysis of 13C and 15N were performed on solid state event and source material. Future work will include examination of microbial communities associated with POM particle size classes. Physical size class separation of within-event POM exhibited differences in C:N ratios, δ15N composition, and extracted DOM lability. Smaller size classes exhibited lower C:N ratios, more enriched δ15N and more recalcitrant properties in leached DOM. Source material had varying C:N ratios and contributions to leached DOM. These results indicate that both source and size class strongly influence the POM contribution to fluvial systems during large storm events.

  3. Correlation analysis for the incubation period of prion disease.

    PubMed

    Bae, Se-Eun; Jung, Sunghoon; Kim, Ha-Yeon; Son, Hyeon S

    2012-07-01

    Previous studies have shown that genetic quantitative trait loci (QTL), strain barriers, inoculation dose and inoculation method modulate the incubation period of prion diseases. We examined the relationship between a diverse set of physical, genetic and immunological characteristics and the incubation period of prion disease using correlation analyses. We found that incubation period was highly correlated with brain weight. In addition, mean corpuscular volume and cell size were strongly correlated with incubation period, indicating that the physical magnitude of prion-infected organs or individual cells may be important in determining the incubation period. Given the same prion inoculation dose, animals with a lower brain weight, mean corpuscular volume or cell size may experience more virulent disease, as the effective concentration of abnormal prion, which might regulate the attachment rate of prions to aggregates, is increased with smaller capacity of brains and cells. This is partly consistent with previous theoretical modeling. The strong correlations between incubation period and physical properties of the brain and cells in this study suggest that the mechanism underlying prion disease pathology may be physical, indicating that the incubation process is governed by simple chemical stoichiometry.

  4. The notion of snow grain shape: Ambiguous definitions, retrievalfrom tomography and implications on remote sensing

    NASA Astrophysics Data System (ADS)

    Krol, Q. E.; Loewe, H.

    2016-12-01

    Grain shape is known to influence the effective physical properties of snow and therefore included in the international classification of seasonal snow. Accordingly, snowpack models account for phenomenological shape parameters (sphericity, dendricity) to capture shape variations. These parameters are however difficult to validate due to the lack of clear-cut definitions from the 3D microstucture and insufficient links to physical properties. While the definition of traditional shape was tailored to the requirements of observers, a more objective definition should be tailored to the requirements of physical properties, by analyzing geometrical (shape) corrections in existing theoretical formulations directly. To this end we revisited the autocorrelation function (ACF) and the chord length distribution (CLD) of snow. Both functions capture size distributions of the microstructure, can be calculated from X-ray tomography and are related to various physical properties. Both functions involve the optical equivalent diameter as dominant quantity, however the respective higher-order geometrical correction differ. We have analyzed these corrections, namely interfacial curvatures for the ACF and the second moment for the CLD, using an existing data set of 165 tomography samples. To unify the notion of shape, we derived various statistical relations between the length scales. Our analysis bears three key practical implications. First, we derived a significantly improved relation between the exponential correlation length and the optical diameter by taking curvatures into account. This adds to the understanding of linking "microwave grain size" and "optical grain size" of snow for remote sensing. Second, we retrieve the optical shape parameter (commonly referred to as B) from tomography images via the moment of the CLD. Third, shape variations seen by observers do not necessarily correspond to shape variations probed by physical properties.

  5. Theophylline-nicotinamide cocrystal formation in physical mixture during storage.

    PubMed

    Ervasti, Tuomas; Aaltonen, Jaakko; Ketolainen, Jarkko

    2015-01-01

    Pharmaceutically relevant properties, such as solubility and dissolution rate, of active pharmaceutical ingredients can be enhanced by cocrystal formation. Theophylline and nicotinamide are known to form cocrystals, for example if subjected to solid-state grinding. However, under appropriate conditions, cocrystals can also form in physical mixtures without any mechanical activation. The purpose of this work was to study whether theophylline and nicotinamide could form cocrystals spontaneously, without mechanical activation. Crystalline theophylline and nicotinamide powders were gently mixed manually in a 1:1 molar ratio and stored at different relative humidity and temperature conditions. The solid state of the samples was analyzed by differential scanning calorimetry, Raman spectroscopy and X-ray powder diffractometry. Three different variations of theophylline were used as starting materials, e.g., two size fractions of theophylline anhydrate (large 710 μm-1 mm and small 180-355 μm), and monohydrate (recrystallized from water). As a reference, anhydrous theophylline-nicotinamide cocrystals were prepared by solid-state grinding. The results of this study indicate that theophylline-nicotinamide cocrystals can form without any mechanical activation from physical mixtures of theophylline and nicotinamide during storage. For anhydrous samples, storage humidity was found to be a critical parameter for cocrystal formation. Increasing temperature was also found to have an accelerating effect on the transformation. The effect of particle size of anhydrous theophylline on the transformation rate could not be completely resolved; DSC and Raman indicated slightly faster transformation with a physical mixture prepared from large size fraction of anhydrous theophylline, but the differences were only minor. Cocrystal formation was also observed in the physical mixture prepared from theophylline monohydrate, but the rate was not as high as with samples prepared from anhydrous material. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Fibromyalgia has a larger impact on physical health than on psychological health, yet both are markedly affected: the al-Ándalus project.

    PubMed

    Segura-Jiménez, Víctor; Álvarez-Gallardo, Inmaculada C; Carbonell-Baeza, Ana; Aparicio, Virginia A; Ortega, Francisco B; Casimiro, Antonio J; Delgado-Fernández, Manuel

    2015-04-01

    To characterize a representative sample of fibromyalgia women based on a set of relevant factors known to be related to this disease. To distinguish specific factors of the disease from other symptoms that might also exist in non-fibromyalgia women. To test whether fibromyalgia affects more severely physical or psychological outcomes. A total of 459 fibromyalgia women vs. 214 non-fibromyalgia (control) women from Southern Spain (Andalusia) took part in this cross-sectional study. Several instruments were used to assess tenderness, impact of fibromyalgia, fatigue, health-related quality of life, mental health, and cognitive performance. Overall, fibromyalgia women showed a worse status in pain, fatigue, health-related quality of life, depression, and anxiety than controls (P < 0.01). In general, the observed associations presented very large effect sizes (Cohen׳s d from ~1 to ~5.5). No differences between fibromyalgia and controls were observed in cognitive and memory performance, except for delayed recall, but the observed effect size was low (~0.25). The effect size observed for the global physical component (~3.3) was larger than that for the global psychological component (~1.3), all P < 0.001. Our results reinforce the understanding of fibromyalgia as a polysymptomatic distress condition with pain as its main symptom. Our findings support that fibromyalgia seems to have a greater impact on physical than on psychological outcomes, though both are largely affected. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. High-yield fabrication and properties of 1.4 nm nanodiamonds with narrow size distribution

    NASA Astrophysics Data System (ADS)

    Stehlik, Stepan; Varga, Marian; Ledinsky, Martin; Miliaieva, Daria; Kozak, Halyna; Skakalova, Viera; Mangler, Clemens; Pennycook, Timothy J.; Meyer, Jannik C.; Kromka, Alexander; Rezek, Bohuslav

    2016-12-01

    Detonation nanodiamonds (DNDs) with a typical size of 5 nm have attracted broad interest in science and technology. Further size reduction of DNDs would bring these nanoparticles to the molecular-size level and open new prospects for research and applications in various fields, ranging from quantum physics to biomedicine. Here we show a controllable size reduction of the DND mean size down to 1.4 nm without significant particle loss and with additional disintegration of DND core agglutinates by air annealing, leading to a significantly narrowed size distribution (±0.7 nm). This process is scalable to large quantities. Such molecular-sized DNDs keep their diamond structure and characteristic DND features as shown by Raman spectroscopy, infrared spectroscopy, STEM and EELS. The size of 1 nm is identified as a limit, below which the DNDs become amorphous.

  8. High-yield fabrication and properties of 1.4 nm nanodiamonds with narrow size distribution

    PubMed Central

    Stehlik, Stepan; Varga, Marian; Ledinsky, Martin; Miliaieva, Daria; Kozak, Halyna; Skakalova, Viera; Mangler, Clemens; Pennycook, Timothy J.; Meyer, Jannik C.; Kromka, Alexander; Rezek, Bohuslav

    2016-01-01

    Detonation nanodiamonds (DNDs) with a typical size of 5 nm have attracted broad interest in science and technology. Further size reduction of DNDs would bring these nanoparticles to the molecular-size level and open new prospects for research and applications in various fields, ranging from quantum physics to biomedicine. Here we show a controllable size reduction of the DND mean size down to 1.4 nm without significant particle loss and with additional disintegration of DND core agglutinates by air annealing, leading to a significantly narrowed size distribution (±0.7 nm). This process is scalable to large quantities. Such molecular-sized DNDs keep their diamond structure and characteristic DND features as shown by Raman spectroscopy, infrared spectroscopy, STEM and EELS. The size of 1 nm is identified as a limit, below which the DNDs become amorphous. PMID:27910924

  9. High-yield fabrication and properties of 1.4 nm nanodiamonds with narrow size distribution.

    PubMed

    Stehlik, Stepan; Varga, Marian; Ledinsky, Martin; Miliaieva, Daria; Kozak, Halyna; Skakalova, Viera; Mangler, Clemens; Pennycook, Timothy J; Meyer, Jannik C; Kromka, Alexander; Rezek, Bohuslav

    2016-12-02

    Detonation nanodiamonds (DNDs) with a typical size of 5 nm have attracted broad interest in science and technology. Further size reduction of DNDs would bring these nanoparticles to the molecular-size level and open new prospects for research and applications in various fields, ranging from quantum physics to biomedicine. Here we show a controllable size reduction of the DND mean size down to 1.4 nm without significant particle loss and with additional disintegration of DND core agglutinates by air annealing, leading to a significantly narrowed size distribution (±0.7 nm). This process is scalable to large quantities. Such molecular-sized DNDs keep their diamond structure and characteristic DND features as shown by Raman spectroscopy, infrared spectroscopy, STEM and EELS. The size of 1 nm is identified as a limit, below which the DNDs become amorphous.

  10. A Collaboration Between University and High School in Preparing Physics Teachers: Chicago State University's Teacher Immersion Institutea)

    NASA Astrophysics Data System (ADS)

    Sabella, Mel S.; Van Duzor, Andrea G.; Passehl, Jennie; Weisenburger, Kara

    2012-05-01

    Because of the diverse character of colleges and universities throughout the United States, it is naive to believe that a one-size-fits-all model of teacher preparation aligns with specific resources and student population needs. Exploring innovative models that challenge traditional programs is now being encouraged by organizations such as the American Association of Physics Teachers and the American Physical Society. Chicago State University (CSU) is now exploring exciting changes to its physics teacher preparation program by utilizing the expertise of Chicago Area teachers and early teaching experiences for students interested in, but not yet committed to, the physics teaching profession.

  11. Hydrate morphology: Physical properties of sands with patchy hydrate saturation

    USGS Publications Warehouse

    Dai, S.; Santamarina, J.C.; Waite, William F.; Kneafsey, T.J.

    2012-01-01

    The physical properties of gas hydrate-bearing sediments depend on the volume fraction and spatial distribution of the hydrate phase. The host sediment grain size and the state of effective stress determine the hydrate morphology in sediments; this information can be used to significantly constrain estimates of the physical properties of hydrate-bearing sediments, including the coarse-grained sands subjected to high effective stress that are of interest as potential energy resources. Reported data and physical analyses suggest hydrate-bearing sands contain a heterogeneous, patchy hydrate distribution, whereby zones with 100% pore-space hydrate saturation are embedded in hydrate-free sand. Accounting for patchy rather than homogeneous hydrate distribution yields more tightly constrained estimates of physical properties in hydrate-bearing sands and captures observed physical-property dependencies on hydrate saturation. For example, numerical modeling results of sands with patchy saturation agree with experimental observation, showing a transition in stiffness starting near the series bound at low hydrate saturations but moving toward the parallel bound at high hydrate saturations. The hydrate-patch size itself impacts the physical properties of hydrate-bearing sediments; for example, at constant hydrate saturation, we find that conductivity (electrical, hydraulic and thermal) increases as the number of hydrate-saturated patches increases. This increase reflects the larger number of conductive flow paths that exist in specimens with many small hydrate-saturated patches in comparison to specimens in which a few large hydrate saturated patches can block flow over a significant cross-section of the specimen.

  12. Prediction of activity-related energy expenditure using accelerometer-derived physical activity under free-living conditions: a systematic review.

    PubMed

    Jeran, S; Steinbrecher, A; Pischon, T

    2016-08-01

    Activity-related energy expenditure (AEE) might be an important factor in the etiology of chronic diseases. However, measurement of free-living AEE is usually not feasible in large-scale epidemiological studies but instead has traditionally been estimated based on self-reported physical activity. Recently, accelerometry has been proposed for objective assessment of physical activity, but it is unclear to what extent this methods explains the variance in AEE. We conducted a systematic review searching MEDLINE database (until 2014) on studies that estimated AEE based on accelerometry-assessed physical activity in adults under free-living conditions (using doubly labeled water method). Extracted study characteristics were sample size, accelerometer (type (uniaxial, triaxial), metrics (for example, activity counts, steps, acceleration), recording period, body position, wear time), explained variance of AEE (R(2)) and number of additional predictors. The relation of univariate and multivariate R(2) with study characteristics was analyzed using nonparametric tests. Nineteen articles were identified. Examination of various accelerometers or subpopulations in one article was treated separately, resulting in 28 studies. Sample sizes ranged from 10 to 149. In most studies the accelerometer was triaxial, worn at the trunk, during waking hours and reported activity counts as output metric. Recording periods ranged from 5 to 15 days. The variance of AEE explained by accelerometer-assessed physical activity ranged from 4 to 80% (median crude R(2)=26%). Sample size was inversely related to the explained variance. Inclusion of 1 to 3 other predictors in addition to accelerometer output significantly increased the explained variance to a range of 12.5-86% (median total R(2)=41%). The increase did not depend on the number of added predictors. We conclude that there is large heterogeneity across studies in the explained variance of AEE when estimated based on accelerometry. Thus, data on predicted AEE based on accelerometry-assessed physical activity need to be interpreted cautiously.

  13. Telemedicine Physical Examination Utilizing a Consumer Device Demonstrates Poor Concordance with In-Person Physical Examination in Emergency Department Patients with Sore Throat: A Prospective Blinded Study.

    PubMed

    Akhtar, Moneeb; Van Heukelom, Paul G; Ahmed, Azeemuddin; Tranter, Rachel D; White, Erinn; Shekem, Nathaniel; Walz, David; Fairfield, Catherine; Vakkalanka, J Priyanka; Mohr, Nicholas M

    2018-02-22

    Telemedicine allows patients to connect with healthcare providers remotely. It has recently expanded to evaluate low-acuity illnesses such as pharyngitis by using patients' personal communication devices. The purpose of our study was to compare the telemedicine-facilitated physical examination with an in-person examination in emergency department (ED) patients with sore throat. This was a prospective, observational, blinded diagnostic concordance study of patients being seen for sore throat in a 60,000-visit Midwestern academic ED. A telemedicine and a face-to-face examination were performed independently by two advanced practice providers (APP), blinded to the results of the other evaluator. The primary outcome was agreement on pharyngeal redness between the evaluators, with secondary outcomes of agreement and inter-rater reliability on 14 other aspects of the pharyngeal physical examination. We also conducted a survey of patients and providers to evaluate perceptions and preferences for sore throat evaluation using telemedicine. Sixty-two patients were enrolled, with a median tonsil size of 1.0. Inter-rater agreement (kappa) for tonsil size was 0.394, which was worse than our predetermined concordance threshold. Other kappa values ranged from 0 to 0.434, and telemedicine was best for detecting abnormal coloration of the palate and tender superficial cervical lymph nodes (anterior structures), but poor for detecting abnormal submandibular lymph nodes or asymmetry of the posterior pharynx (posterior structures). In survey responses, telemedicine was judged easier to use and more comfortable for providers than patients; however, neither patients nor providers preferred in-person to telemedicine evaluation. Telemedicine exhibited poor agreement with the in-person physical examination on the primary outcome of tonsil size, but exhibited moderate agreement on coloration of the palate and cervical lymphadenopathy. Future work should better characterize the importance of the physical examination in treatment decisions for patients with sore throat and the use of telemedicine in avoiding in-person healthcare visits.

  14. Role of Physical Bolus Properties as Sensory Inputs in the Trigger of Swallowing

    PubMed Central

    Peyron, Marie-Agnès; Gierczynski, Isabelle; Hartmann, Christoph; Loret, Chrystel; Dardevet, Dominique; Martin, Nathalie; Woda, Alain

    2011-01-01

    Background Swallowing is triggered when a food bolus being prepared by mastication has reached a defined state. However, although this view is consensual and well supported, the physical properties of the swallowable bolus have been under-researched. We tested the hypothesis that measuring bolus physical changes during the masticatory sequence to deglutition would reveal the bolus properties potentially involved in swallowing initiation. Methods Twenty normo-dentate young adults were instructed to chew portions of cereal and spit out the boluses at different times in the masticatory sequence. The mechanical properties of the collected boluses were measured by a texture profile analysis test currently used in food science. The median particle size of the boluses was evaluated by sieving. In a simultaneous sensory study, twenty-five other subjects expressed their perception of bolus texture dominating at any mastication time. Findings Several physical changes appeared in the food bolus as it was formed during mastication: (1) in rheological terms, bolus hardness rapidly decreased as the masticatory sequence progressed, (2) by contrast, adhesiveness, springiness and cohesiveness regularly increased until the time of swallowing, (3) median particle size, indicating the bolus particle size distribution, decreased mostly during the first third of the masticatory sequence, (4) except for hardness, the rheological changes still appeared in the boluses collected just before swallowing, and (5) physical changes occurred, with sensory stickiness being described by the subjects as a dominant perception of the bolus at the end of mastication. Conclusions Although these physical and sensory changes progressed in the course of mastication, those observed just before swallowing seem to be involved in swallowing initiation. They can be considered as strong candidates for sensory inputs from the bolus that are probably crucially involved in the triggering of swallowing, since they appeared in boluses prepared in various mastication strategies by different subjects. PMID:21738616

  15. The Effectiveness of Dance Interventions on Physical Health Outcomes Compared to Other Forms of Physical Activity: A Systematic Review and Meta-Analysis.

    PubMed

    Fong Yan, Alycia; Cobley, Stephen; Chan, Cliffton; Pappas, Evangelos; Nicholson, Leslie L; Ward, Rachel E; Murdoch, Roslyn E; Gu, Yu; Trevor, Bronwyn L; Vassallo, Amy Jo; Wewege, Michael A; Hiller, Claire E

    2018-04-01

    Physical inactivity is one of the key global health challenges as it is associated with adverse effects related to ageing, weight control, physical function, longevity, and quality of life. Dancing is a form of physical activity associated with health benefits across the lifespan, even at amateur levels of participation. However, it is unclear whether dance interventions are equally as effective as other forms of physical activity. The aim was to systematically review the literature on the effectiveness of structured dance interventions, in comparison to structured exercise programmes, on physical health outcome measures. Seven databases were searched from earliest records to 4 August 2017. Studies investigating dance interventions lasting > 4 weeks that included physical health outcomes and had a structured exercise comparison group were included in the study. Screening and data extraction were performed by two reviewers, with all disagreements resolved by the primary author. Where appropriate, meta-analysis was performed or an effect size estimate generated. Of 11,434 studies identified, 28 (total sample size 1276 participants) met the inclusion criteria. A variety of dance genres and structured exercise interventions were compared. Meta-analyses showed dance interventions significantly improved body composition, blood biomarkers, and musculoskeletal function. The effect of either intervention on cardiovascular function and self-perceived mobility was equivalent. Undertaking structured dance of any genre is equally and occasionally more effective than other types of structured exercise for improving a range of health outcome measures. Health practitioners can recommend structured dance as a safe and effective exercise alternative.

  16. The effect of polymers onto the size of zinc layered hydroxide salt and its calcined product

    NASA Astrophysics Data System (ADS)

    Hussein, Mohd Zobir bin; Ghotbi, Mohammad Yeganeh; Yahaya, Asmah Hj; Abd Rahman, Mohd Zaki

    2009-02-01

    Zinc hydroxide nitrate, a brucite-like layered material was synthesized using pH control method. Poly(vinyl alcohol) and poly(ethylene glycol) were used at various percentages as size decreasing agents during the synthesis of zinc hydroxide nitrate. SEM and PXRD showed the decrease of size and thickness of the resultant zinc hydroxide nitrates. TG and surface area data confirmed the decrease of the particle sizes, too. When zinc hydroxide nitrates were heat treated at 500 °C, the physical properties of nano zinc oxides obtained depended on the parent material, zinc hydroxide nitrate.

  17. Generation Changes over the Period of 1986-2006 in the Physical Fitness of Boys Aged 7-19 from Eastern Poland at Particular Stages of Education

    ERIC Educational Resources Information Center

    Saczuk, Jerzy; Wasiluk, Agnieszka; Zalech, Miroslaw

    2012-01-01

    Study aim: To assess the size of secular trends in the physical fitness of boys from eastern Poland taking into consideration stages of education. Material and methods: The physical fitness results of boys aged 7-19 years living in eastern regions of Poland were analyzed: 3188 students were examined in 1986 while in 2006 the research included 10…

  18. Effect of dislocation pile-up on size-dependent yield strength in finite single-crystal micro-samples

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pan, Bo; Shibutani, Yoji, E-mail: sibutani@mech.eng.osaka-u.ac.jp; Zhang, Xu

    2015-07-07

    Recent research has explained that the steeply increasing yield strength in metals depends on decreasing sample size. In this work, we derive a statistical physical model of the yield strength of finite single-crystal micro-pillars that depends on single-ended dislocation pile-up inside the micro-pillars. We show that this size effect can be explained almost completely by considering the stochastic lengths of the dislocation source and the dislocation pile-up length in the single-crystal micro-pillars. The Hall–Petch-type relation holds even in a microscale single-crystal, which is characterized by its dislocation source lengths. Our quantitative conclusions suggest that the number of dislocation sources andmore » pile-ups are significant factors for the size effect. They also indicate that starvation of dislocation sources is another reason for the size effect. Moreover, we investigated the explicit relationship between the stacking fault energy and the dislocation “pile-up” effect inside the sample: materials with low stacking fault energy exhibit an obvious dislocation pile-up effect. Our proposed physical model predicts a sample strength that agrees well with experimental data, and our model can give a more precise prediction than the current single arm source model, especially for materials with low stacking fault energy.« less

  19. Modified Continuum Mechanics Modeling on Size-Dependent Properties of Piezoelectric Nanomaterials: A Review

    PubMed Central

    Yan, Zhi; Jiang, Liying

    2017-01-01

    Piezoelectric nanomaterials (PNs) are attractive for applications including sensing, actuating, energy harvesting, among others in nano-electro-mechanical-systems (NEMS) because of their excellent electromechanical coupling, mechanical and physical properties. However, the properties of PNs do not coincide with their bulk counterparts and depend on the particular size. A large amount of efforts have been devoted to studying the size-dependent properties of PNs by using experimental characterization, atomistic simulation and continuum mechanics modeling with the consideration of the scale features of the nanomaterials. This paper reviews the recent progresses and achievements in the research on the continuum mechanics modeling of the size-dependent mechanical and physical properties of PNs. We start from the fundamentals of the modified continuum mechanics models for PNs, including the theories of surface piezoelectricity, flexoelectricity and non-local piezoelectricity, with the introduction of the modified piezoelectric beam and plate models particularly for nanostructured piezoelectric materials with certain configurations. Then, we give a review on the investigation of the size-dependent properties of PNs by using the modified continuum mechanics models, such as the electromechanical coupling, bending, vibration, buckling, wave propagation and dynamic characteristics. Finally, analytical modeling and analysis of nanoscale actuators and energy harvesters based on piezoelectric nanostructures are presented. PMID:28336861

  20. Modified Continuum Mechanics Modeling on Size-Dependent Properties of Piezoelectric Nanomaterials: A Review.

    PubMed

    Yan, Zhi; Jiang, Liying

    2017-01-26

    Piezoelectric nanomaterials (PNs) are attractive for applications including sensing, actuating, energy harvesting, among others in nano-electro-mechanical-systems (NEMS) because of their excellent electromechanical coupling, mechanical and physical properties. However, the properties of PNs do not coincide with their bulk counterparts and depend on the particular size. A large amount of efforts have been devoted to studying the size-dependent properties of PNs by using experimental characterization, atomistic simulation and continuum mechanics modeling with the consideration of the scale features of the nanomaterials. This paper reviews the recent progresses and achievements in the research on the continuum mechanics modeling of the size-dependent mechanical and physical properties of PNs. We start from the fundamentals of the modified continuum mechanics models for PNs, including the theories of surface piezoelectricity, flexoelectricity and non-local piezoelectricity, with the introduction of the modified piezoelectric beam and plate models particularly for nanostructured piezoelectric materials with certain configurations. Then, we give a review on the investigation of the size-dependent properties of PNs by using the modified continuum mechanics models, such as the electromechanical coupling, bending, vibration, buckling, wave propagation and dynamic characteristics. Finally, analytical modeling and analysis of nanoscale actuators and energy harvesters based on piezoelectric nanostructures are presented.

  1. A sampling strategy for promoting and assessing medical student retention of physical examination skills.

    PubMed

    Williams, Reed G; Klamen, Debra L; Mayer, David; Valaski, Maureen; Roberts, Nicole K

    2007-10-01

    Skill acquisition and maintenance requires spaced deliberate practice. Assessing medical students' physical examination performance ability is resource intensive. The authors assessed the nature and size of physical examination performance samples necessary to accurately estimate total physical examination skill. Physical examination assessment data were analyzed from second year students at the University of Illinois College of Medicine at Chicago in 2002, 2003, and 2004 (N = 548). Scores on subgroups of physical exam maneuvers were compared with scores on the total physical exam, to identify sound predictors of total test performance. Five exam subcomponents were sufficiently correlated to overall test performance and provided adequate sensitivity and specificity to serve as a means to prompt continued student review and rehearsal of physical examination technical skills. Selection and administration of samples of the total physical exam provide a resource-saving approach for promoting and estimating overall physical examination skills retention.

  2. Physical properties evaluation of roselle extract-egg white mixture under various drying temperatures

    NASA Astrophysics Data System (ADS)

    Triyastuti, M. S.; Kumoro, A. C.; Djaeni, M.

    2017-03-01

    Roselle contains anthocyanin that is potential for food colorant. Occasionally, roselle extract is provided in dry powder prepared under high temperature. In this case, the anthocyanin color degrades due to the intervention of heat. The foammat drying with egg white is a potential method to speed up the drying process as well as minimize color degradation. This research aims to study the physical properties of roselle extract under foam mat drying. As indicators, the powder size and color intensity were observed. The result showed that at high temperatures, roselle powder under foam mat drying has the fine size with porous structure. However, at the higher the drying temperature the color retention decreased.

  3. Reevaluating the two-representation model of numerical magnitude processing.

    PubMed

    Jiang, Ting; Zhang, Wenfeng; Wen, Wen; Zhu, Haiting; Du, Han; Zhu, Xiangru; Gao, Xuefei; Zhang, Hongchuan; Dong, Qi; Chen, Chuansheng

    2016-01-01

    One debate in mathematical cognition centers on the single-representation model versus the two-representation model. Using an improved number Stroop paradigm (i.e., systematically manipulating physical size distance), in the present study we tested the predictions of the two models for number magnitude processing. The results supported the single-representation model and, more importantly, explained how a design problem (failure to manipulate physical size distance) and an analytical problem (failure to consider the interaction between congruity and task-irrelevant numerical distance) might have contributed to the evidence used to support the two-representation model. This study, therefore, can help settle the debate between the single-representation and two-representation models.

  4. Space astrophysics with large structures - CASES and P/OF. [Controls, Astrophysics, and Structures Experiment in Space and Pinhole/Occulter Facility

    NASA Technical Reports Server (NTRS)

    Hudson, Hugh S.; Davis, J. M.

    1990-01-01

    Space instruments for remote sensing, of the types used for astrophysics and solar-terrestrial physics among many disciplines, will grow to larger physical sizes in the future. The zero-g space environment does not inherently restrict such growth, because relatively lightweight structures can be used. Active servo control of the structures can greatly increase their size for a given mass. The Pinhole/Occulter Facility, a candidate Space Station attached payload, offers an example: it will achieve 0.2 arc s resolution by use of a 50-m baseline for coded-aperture telescopes for hard X-ray and gamma-ray imagers.

  5. Consistent Measurement and Physical Character of the DSD: Disdrometer to Satellite

    NASA Technical Reports Server (NTRS)

    Petersen, Walt; Thurai, Merhala; Gatlin, Patrick; Tokay, Ali; Morris, Bob; Wolff, David; Pippitt, Jason; Marks, David; Berendes, Todd

    2017-01-01

    Objective: Validate GPM (Global Precipitation Measurement) Drop Size Distribution Retrievals: Drop size distributions (DSD) are critical to GPM DPR (Dual-frequency Precipitation Radar)-based rainfall retrievals; NASA GPM Science Requirements stipulate that the GPM Core observatory radar estimation of D (sub m) (mean diameter) shall be within plus or minus 0.5 millimeters of GV (Ground Validation); GV translates disdrometer measurements to polarimetric radar-based DSD and precipitation type retrievals (e.g., convective vs. stratiform (C/S)) for coincident match-up to GPM core overpasses; How well do we meet the requirement across product versions, rain types (e.g., C/S partitioning), and rain rates (heavy, light) and is behavior physically and internally consistent?

  6. Sensitivity analysis of non-cohesive sediment transport formulae

    NASA Astrophysics Data System (ADS)

    Pinto, Lígia; Fortunato, André B.; Freire, Paula

    2006-10-01

    Sand transport models are often based on semi-empirical equilibrium transport formulae that relate sediment fluxes to physical properties such as velocity, depth and characteristic sediment grain sizes. In engineering applications, errors in these physical properties affect the accuracy of the sediment fluxes. The present analysis quantifies error propagation from the input physical properties to the sediment fluxes, determines which ones control the final errors, and provides insight into the relative strengths, weaknesses and limitations of four total load formulae (Ackers and White, Engelund and Hansen, van Rijn, and Karim and Kennedy) and one bed load formulation (van Rijn). The various sources of uncertainty are first investigated individually, in order to pinpoint the key physical properties that control the errors. Since the strong non-linearity of most sand transport formulae precludes analytical approaches, a Monte Carlo method is validated and used in the analysis. Results show that the accuracy in total sediment transport evaluations is mainly determined by errors in the current velocity and in the sediment median grain size. For the bed load transport using the van Rijn formula, errors in the current velocity alone control the final accuracy. In a final set of tests, all physical properties are allowed to vary simultaneously in order to analyze the combined effect of errors. The combined effect of errors in all the physical properties is then compared to an estimate of the errors due to the intrinsic limitations of the formulae. Results show that errors in the physical properties can be dominant for typical uncertainties associated with these properties, particularly for small depths. A comparison between the various formulae reveals that the van Rijn formula is more sensitive to basic physical properties. Hence, it should only be used when physical properties are known with precision.

  7. The Physics of Boundary-Layer Aero-Optic Effects

    DTIC Science & Technology

    2012-09-01

    various models to predict aero-optical effects for both subsonic and supersonic Mach numbers, laser beam sizes and non- adiabatic walls. The developed...models to predict aero-optical effects for both subsonic and supersonic Mach numbers, laser beam sizes and non- adiabatic walls. The developed models were... Supersonic Facilities .................................................................................................... 8 3.3 2-D Wavefront Data

  8. The Manufacturing Process of Bamboo Pellets

    Treesearch

    Zhijia Liu; Zehui Jiang; Zhiyong Cai; Benhua Fei; Xing' e Liu

    2012-01-01

    Bamboo was a kind of biomass materials and had great potential as a bio-energy resource of the future in China. The physical and combustion properties of bamboo pellets were determined and the effects of moisture content (MC) and sizes of particle on these properties were investigated in this research. The results showed that MC and sizes of particle affected these...

  9. Why Do Marbles Become Paler on Grinding? Reflectance, Spectroscopy, Color, and Particle Size

    ERIC Educational Resources Information Center

    Lagorio, Maria Gabriela

    2004-01-01

    A qualitative description of the color-change problem, which will assist in rationalizing the change in color of marbles after grinding them using a simple physical picture and the qualitative dependence of diffuse reflectance on particle size is presented. Different approaches are discussed but it is seen that the interpretation of nanoparticles…

  10. Development of property-transfer models for estimating the hydraulic properties of deep sediments at the Idaho National Engineering and Environmental Laboratory, Idaho

    USGS Publications Warehouse

    Winfield, Kari A.

    2005-01-01

    Because characterizing the unsaturated hydraulic properties of sediments over large areas or depths is costly and time consuming, development of models that predict these properties from more easily measured bulk-physical properties is desirable. At the Idaho National Engineering and Environmental Laboratory, the unsaturated zone is composed of thick basalt flow sequences interbedded with thinner sedimentary layers. Determining the unsaturated hydraulic properties of sedimentary layers is one step in understanding water flow and solute transport processes through this complex unsaturated system. Multiple linear regression was used to construct simple property-transfer models for estimating the water-retention curve and saturated hydraulic conductivity of deep sediments at the Idaho National Engineering and Environmental Laboratory. The regression models were developed from 109 core sample subsets with laboratory measurements of hydraulic and bulk-physical properties. The core samples were collected at depths of 9 to 175 meters at two facilities within the southwestern portion of the Idaho National Engineering and Environmental Laboratory-the Radioactive Waste Management Complex, and the Vadose Zone Research Park southwest of the Idaho Nuclear Technology and Engineering Center. Four regression models were developed using bulk-physical property measurements (bulk density, particle density, and particle size) as the potential explanatory variables. Three representations of the particle-size distribution were compared: (1) textural-class percentages (gravel, sand, silt, and clay), (2) geometric statistics (mean and standard deviation), and (3) graphical statistics (median and uniformity coefficient). The four response variables, estimated from linear combinations of the bulk-physical properties, included saturated hydraulic conductivity and three parameters that define the water-retention curve. For each core sample,values of each water-retention parameter were estimated from the appropriate regression equation and used to calculate an estimated water-retention curve. The degree to which the estimated curve approximated the measured curve was quantified using a goodness-of-fit indicator, the root-mean-square error. Comparison of the root-mean-square-error distributions for each alternative particle-size model showed that the estimated water-retention curves were insensitive to the way the particle-size distribution was represented. Bulk density, the median particle diameter, and the uniformity coefficient were chosen as input parameters for the final models. The property-transfer models developed in this study allow easy determination of hydraulic properties without need for their direct measurement. Additionally, the models provide the basis for development of theoretical models that rely on physical relationships between the pore-size distribution and the bulk-physical properties of the media. With this adaptation, the property-transfer models should have greater application throughout the Idaho National Engineering and Environmental Laboratory and other geographic locations.

  11. The Size of the Universe and Where Will We Go?

    NASA Technical Reports Server (NTRS)

    Lawson, B. Mike

    2012-01-01

    As an avid engineer and amateur astronomer, Mike Lawson presented a perspective on the size of the universe and asked the question, "Where will we go?" This was an entry-level overview for the average space worker who really wanted to understand the size of stars and the distance between objects in space. Mike provided information about familiar orbital objects and elaborated more on galaxies during the discussion. He also explored where humans could go in space and the physical limitations of going there.

  12. Process-Structure-Property Relationships of Micron Thick Gadolinium Oxide Films Deposited by Reactive Electron Beam-Physical Vapor Deposition (EB-PVD)

    DTIC Science & Technology

    2014-12-01

    surface roughness on film properties must be considered. Stability at the interface between the film and the substrate becomes critical with...etc.). Addition of atoms to the growing surface creates additional surface energy. Therefore, nuclei of a critical size 23 must be formed in order... critical nuclei size and a lower nucleation rate. Higher deposition rates result in a decreased critical nuclei size which leads to an increase in

  13. Magnetic and Optical Properties of Submicron-Size Hollow Spheres

    PubMed Central

    Ye, Quan-Lin; Yoshikawa, Hirofumi; Awaga, Kunio

    2010-01-01

    Magnetic hollow spheres with a controlled diameter and shell thickness have emerged as an important class of magnetic nanomaterials. The confined hollow geometry and pronouncedly curved surfaces induce unique physical properties different from those of flat thin films and solid counterparts. In this paper, we focus on recent progress on submicron-size spherical hollow magnets (e.g., cobalt- and iron-based materials), and discuss the effects of the hollow shape and the submicron size on magnetic and optical properties.

  14. Investigation of Sub-Sized Charpy Specimens

    DTIC Science & Technology

    1945-08-06

    requested the Physical Metallurgy Section to perform a few experiments with sub-sized Charpy spec- imens, so as to indicate whether they could be used to...SAZ 3130 No. 1033 Since the 1020 bpr stock was 2 inches in diameter, four longitu- dinal Charpy speciniens were machined from the cross section as...ihown in Pig- ure 1. In all cases, regardless of the size of the specimen, the center of the height of the Charpy specimen was 5/8 of an inch

  15. The Effect of a Home-Based Walking Intervention on Quality of Life, Body Composition, and Estrogen Metabolism in Postmenopausal Breast Cancer Survivors

    DTIC Science & Technology

    2006-09-01

    Effect sizes are also shown for each randomization group (i.e., effect size from pretest to posttest ) and for the comparison of the two randomization...questions were answered. This study was designed to be a pilot study to quantify effect sizes of the effect of walking on quality of life...physical activity, body composition, and depending on inclusion criteria, estrogen metabolism. Second, this study was designed to assess the degree to

  16. Pain and pain-related interference in adults with lower-limb amputation: comparison of knee-disarticulation, transtibial, and transfemoral surgical sites.

    PubMed

    Behr, James; Friedly, Janna; Molton, Ivan; Morgenroth, David; Jensen, Mark P; Smith, Douglas G

    2009-01-01

    Pain and pain-related interference with physical function have not been thoroughly studied in individuals who have undergone knee-disarticulation amputations. The principal aim of this study was to determine whether individuals with knee-disarticulation amputations have worse pain and pain-related interference with physical function than do individuals with transtibial or transfemoral amputations. We analyzed cross-sectional survey data provided by 42 adults with lower-limb amputations. These individuals consisted of 14 adults reporting knee-disarticulation amputation in one limb and best-matched cases (14 reporting transfemoral amputation and 14 reporting transtibial amputation) from a larger cross-sectional sample of 472 individuals. Participants were rigorously matched based on time since amputation, reason for amputation, age, sex, diabetes diagnosis, and pain before amputation. Continuous outcome variables were analyzed by one-way analysis of variance. Categorical outcomes were analyzed by Pearson chi-square statistic. Given the relatively small sample size and power concerns, mean differences were also described by estimated effect size (Cohen's d). Of the 42 participants, 83% were male. They ranged in age from 36 to 85 (median = 55.1, standard deviation = 11.0). Most amputations were of traumatic origin (74%), and participants were on average 12.4 years from their amputations at the time of the survey. Individuals with transtibial amputation reported significantly more prosthesis use than did individuals with knee-disarticulation amputation. Amputation levels did not significantly differ in phantom limb pain, residual limb pain, back pain, and pain-related interference with physical function. Estimates of effect size, however, indicated that participants with knee-disarticulation amputation reported less phantom limb pain, phantom limb pain-related interference with physical function, residual limb pain, residual limb pain-related interference with physical function, and back pain-related interference with physical function than did participants with transtibial or transfemoral amputations. This study demonstrated that patients with knee-disarticulation amputation used prostheses significantly less than did patients with transtibial amputation. However, no evidence was found that patients with knee-disarticulation amputation have worse outcomes in terms of pain and pain-related interference with physical function; in fact, they may have more favorable long-term outcomes.

  17. The role of lean body mass and physical activity in bone health in children.

    PubMed

    Baptista, Fátima; Barrigas, Carlos; Vieira, Filomena; Santa-Clara, Helena; Homens, Pedro Mil; Fragoso, Isabel; Teixeira, Pedro J; Sardinha, Luís B

    2012-01-01

    In the context of physical education curricula, markers of physical fitness (e.g., aerobic capacity, muscular strength, flexibility, and body mass index or body fat) are usually evaluated in reference to health standards. Despite their possible mediating role in the relationship between weight-bearing or muscle forces and features of bone tissue, these attributes of fitness may not be the most relevant to predict skeletal health. It is therefore important to analyze the relative contribution of these factors to the variability in bone tissue of different parts of the skeleton, and to analyze it by gender, as sensitivity to mechanical loading can diverge for boys and girls. We compared the effects of habitual physical activity (PA) and lean mass, as surrogates of weight-bearing and muscle forces, and of physical fitness (aerobic and muscle capacity of lower and upper limbs) on bone mineral content (BMC) and size of total body, lumbar spine, femoral neck, and 1/3 radius in 53 girls and 64 boys from 7.9 to 9.7 years of age. After controlling for bone age, body mass, body height, and calcium intake, lean mass was the most important predictor of bone size and/or mineral in both genders (p < 0.05), while habitual weight-bearing PA positively influenced BMC in boys (p < 0.05). The effect of muscle in bone was not determined by PA and fitness score did not explain bone variability. Femoral neck was the bone site more closely associated with mechanical loading factors; boys with a PA > 608 counts/min/day (~105 min/day of moderate and vigorous intensity) showed 13-20% more BMC than those with less physical activity, and girls with a lean mass >19 kg showed 12-19% more BMC than those with less lean mass. These findings suggest that lean mass was the most important predictor of bone size and/or mineralization in both genders, while habitual weight-bearing PA appears to positively impact on bone mineral in prepubertal boys and that both lean mass and PA need to be considered in physical education curricula and other health-enhancing programs.

  18. Long-term and baseline recreational physical activity and risk of endometrial cancer: the California Teachers Study.

    PubMed

    Dieli-Conwright, C M; Ma, H; Lacey, J V; Henderson, K D; Neuhausen, S; Horn-Ross, P L; Deapen, D; Sullivan-Halley, J; Bernstein, L

    2013-08-06

    Physical activity may be associated with decreasing endometrial cancer risk; it remains unclear whether the association is modified by body size. Among 93 888 eligible California Teachers Study participants, 976 were diagnosed with incident endometrial cancer between 1995-1996 and 2007. Cox proportional hazards regression methods were used to estimate relative risks (RRs) and 95% confidence intervals (CIs) for endometrial cancer associated with long-term (high school through age 54 years) and baseline (3 years prior to joining the cohort) strenuous and moderate recreational physical activity, overall and by body size. Increased baseline strenuous recreational physical activity was associated with decreased endometrial cancer risk (Ptrend=0.006) with approximately 25% lower risk among women exercising >3 h per week per year than among those exercising <1/2 h per week per year (RR, 0.76; 95% CI, 0.63-0.92). This inverse association was observed among overweight/obese women (body mass index ≥25 kg m(-2); Ptrend=0.006), but not among thinner women (Ptrend=0.12). Baseline moderate activity was associated with lower risk among overweight/obese women. Increasing physical activity, particularly strenuous activity, may be a lifestyle change that overweight and obese women can implement to reduce their endometrial cancer risk.

  19. Analysis of work ability and work-related physical activity of employees in a medium-sized business.

    PubMed

    Wilke, Christiane; Ashton, Philip; Elis, Tobias; Biallas, Bianca; Froböse, Ingo

    2015-12-18

    Work-related physical activity (PA) and work ability are of growing importance in modern working society. There is evidence for age- and job-related differences regarding PA and work ability. This study analyses work ability and work-related PA of employees in a medium-sized business regarding age and occupation. The total sample consists of 148 employees (116 men-78.38% of the sample-and 32 women, accounting for 21.62%; mean age: 40.85 ± 10.07 years). 100 subjects (67.57%) are white-collar workers (WC), and 48 (32.43%) are blue-collar workers (BC). Work ability is measured using the work ability index, and physical activity is obtained via the Global Physical Activity Questionnaire. Work ability shows significant differences regarding occupation (p = 0.001) but not regarding age. Further, significant differences are found for work-related PA concerning occupation (p < 0.0001), but again not for age. Overall, more than half of all subjects meet the current guidelines for physical activity. Work ability is rated as good, yet, a special focus should lie on the promotion during early and late working life. Also, there is still a lack of evidence on the level of work-related PA. Considering work-related PA could add to meeting current activity recommendations.

  20. Optimization of drug loading to improve physical stability of paclitaxel-loaded long-circulating liposomes.

    PubMed

    Kannan, Vinayagam; Balabathula, Pavan; Divi, Murali K; Thoma, Laura A; Wood, George C

    2015-01-01

    The effect of formulation and process parameters on drug loading and physical stability of paclitaxel-loaded long-circulating liposomes was evaluated. The liposomes were prepared by hydration-extrusion method. The formulation parameters such as total lipid content, cholesterol content, saturated-unsaturated lipid ratio, drug-lipid ratio and process parameters such as extrusion pressure and number of extrusion cycles were studied and their impact on drug loading and physical stability was evaluated. A proportionate increase in drug loading was observed with increase in the total phospholipid content. Cholesterol content and saturated lipid content in the bilayer showed a negative influence on drug loading. The short-term stability evaluation of liposomes prepared with different drug-lipid ratios demonstrated that 1:60 as the optimum drug-lipid ratio to achieve a loading of 1-1.3 mg/mL without the risk of physical instability. The vesicle size decreased with an increase in the extrusion pressure and number of extrusion cycles, but no significant trends were observed for drug loading with changes in process pressure or number of cycles. The optimization of formulation and process parameters led to a physically stable formulation of paclitaxel-loaded long-circulating liposomes that maintain size, charge and integrity during storage.

  1. Gender, BMI, Values, and Learning in Physical Education: A Study on Chinese Middle Schoolers

    ERIC Educational Resources Information Center

    Ding, Haiyong; Sun, Haichun; Chen, Ang

    2011-01-01

    Students' different perceptions of task values influence their learning experience and achievement in physical education. Framed using the subjective task value construct, this study was conducted to determine the extent to which male and female Chinese middle schoolers with different body sizes differed in their perception of the task values. A…

  2. Planck's Constant as a Natural Unit of Measurement

    ERIC Educational Resources Information Center

    Quincey, Paul

    2013-01-01

    The proposed revision of SI units would embed Planck's constant into the definition of the kilogram, as a fixed constant of nature. Traditionally, Planck's constant is not readily interpreted as the size of something physical, and it is generally only encountered by students in the mathematics of quantum physics. Richard Feynman's…

  3. Intuitive Physics of Collision Effects on Simulated Spheres Differing in Size, Velocity, and Material

    ERIC Educational Resources Information Center

    Vicovaro, Michele

    2012-01-01

    This is an intuitive physics study of collision events. In two experiments the participants were presented with a simulated 3D scene showing one sphere moving horizontally towards another stationary sphere. The moving sphere stopped just before colliding with the stationary one. Participants were asked to rate the positions which both spheres…

  4. Impact of petroleum products on soil composition and physical-chemical properties

    NASA Astrophysics Data System (ADS)

    Brakorenko, N. N.; Korotchenko, T. V.

    2016-03-01

    The article describes the grain-size distribution, physical and mechanical properties, swelling and specific electrical resistivity of soils before and after the contact with petroleum products. The changes in mechanical properties of soils contaminated with petroleum products have been stated. It leads to the increase in compressibility values, decline in internal friction angle and cohesion.

  5. Demonstration Experiments for Solid-State Physics Using a Table-Top Mechanical Stirling Refrigerator

    ERIC Educational Resources Information Center

    Osorio, M. R.; Morales, A. Palacio; Rodrigo, J. G.; Suderow, H.; Vieira, S.

    2012-01-01

    Liquid-free cryogenic devices are acquiring importance in basic science and engineering. But they can also lead to improvements in teaching low temperature and solid-state physics to graduate students and specialists. Most of the devices are relatively expensive, but small-sized equipment is slowly becoming available. Here, we have designed…

  6. 13 CFR 123.200 - Am I eligible to apply for a physical disaster business loan?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., corporation, limited liability company, or other legal entity recognized under State law. Your business' size... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Am I eligible to apply for a physical disaster business loan? 123.200 Section 123.200 Business Credit and Assistance SMALL BUSINESS...

  7. Graduate Student Report: First-Year Students in 1999 and 2000. AIP Report.

    ERIC Educational Resources Information Center

    Mulvey, Patrick J.; Langer, Casey

    This report provides information on the size and citizenship of the incoming graduate physics and astronomy class and describes student characteristics such as gender and educational background. Data are from the American Institute of Physics Enrollments and Degrees surveys for the 1998-1999 and 1999-2000 academic years. In 1998-1999 there were…

  8. Physical characteristics of indigestible solids affect emptying from the fasting human stomach.

    PubMed Central

    Meyer, B; Beglinger, C; Neumayer, M; Stalder, G A

    1989-01-01

    Gastric emptying of indigestible solids depends on their size. It is not clear whether physical characteristics other than particle size affect emptying of indigestible solids from the fasting human stomach. We studied gastric emptying of three differently shaped particles, (cubes, spheres, rods) of either hard or soft consistency during the fasting state in human volunteers. The shape of indigestible particles did not affect their emptying. The area under the gastric emptying curve (AUC: particles x hour) was for hard cubes 24.7 (2.2), for hard spheres 27.9 (1.6), for hard rods 26.9 (2.7). All soft particles emptied faster than their identically shaped hard counterparts, but there was no difference among the three shapes (AUC for soft cubes: 29.2 (3.0), for soft spheres 32.0 (1.8), for soft rods 34.1 (1.2). If gastric emptying of hard and soft particles was compared independently of their shape, soft particles emptied significantly faster than hard ones: AUC 31.8 (1.2) v 26.5 (1.3) (p less than 0.01). In conclusion, the consistency but not the shape significantly affects gastric emptying. Specific physical characteristics other than size and shape may affect gastric emptying of indigestible particles which may be of importance in the design of drugs. PMID:2599438

  9. Recombination rate predicts inversion size in Diptera.

    PubMed Central

    Cáceres, M; Barbadilla, A; Ruiz, A

    1999-01-01

    Most species of the Drosophila genus and other Diptera are polymorphic for paracentric inversions. A common observation is that successful inversions are of intermediate size. We test here the hypothesis that the selected property is the recombination length of inversions, not their physical length. If so, physical length of successful inversions should be negatively correlated with recombination rate across species. This prediction was tested by a comprehensive statistical analysis of inversion size and recombination map length in 12 Diptera species for which appropriate data are available. We found that (1) there is a wide variation in recombination map length among species; (2) physical length of successful inversions varies greatly among species and is inversely correlated with the species recombination map length; and (3) neither the among-species variation in inversion length nor the correlation are observed in unsuccessful inversions. The clear differences between successful and unsuccessful inversions point to natural selection as the most likely explanation for our results. Presumably the selective advantage of an inversion increases with its length, but so does its detrimental effect on fertility due to double crossovers. Our analysis provides the strongest and most extensive evidence in favor of the notion that the adaptive value of inversions stems from their effect on recombination. PMID:10471710

  10. Enrichment of ODMR-active nitrogen-vacancy centres in five-nanometre-sized detonation-synthesized nanodiamonds: Nanoprobes for temperature, angle and position.

    PubMed

    Sotoma, Shingo; Terada, Daiki; Segawa, Takuya F; Igarashi, Ryuji; Harada, Yoshie; Shirakawa, Masahiro

    2018-04-03

    The development of sensors to estimate physical properties, and their temporal and spatial variation, has been a central driving force in scientific breakthroughs. In recent years, nanosensors based on quantum measurements, such as nitrogen-vacancy centres (NVCs) in nanodiamonds, have been attracting much attention as ultrastable, sensitive, accurate and versatile physical sensors for quantitative cellular measurements. However, the nanodiamonds currently available for use as sensors have diameters of several tens of nanometres, much larger than the usual size of a protein. Therefore, their actual applications remain limited. Here we show that NVCs in an aggregation of 5-nm-sized detonation-synthesized nanodiamond treated by Krüger's surface reduction (termed DND-OH) retains the same characteristics as observed in larger diamonds. We show that the negative charge at the NVC are stabilized, have a relatively long T 2 spin relaxation time of up to 4 μs, and are applicable to thermosensing, one-degree orientation determination and nanometric super-resolution imaging. Our results clearly demonstrate the significant potential of DND-OH as a physical sensor. Thus, DND-OH will raise new possibilities for spatiotemporal monitoring of live cells and dynamic biomolecules in individual cells at single-molecule resolution.

  11. Moving Computational Domain Method and Its Application to Flow Around a High-Speed Car Passing Through a Hairpin Curve

    NASA Astrophysics Data System (ADS)

    Watanabe, Koji; Matsuno, Kenichi

    This paper presents a new method for simulating flows driven by a body traveling with neither restriction on motion nor a limit of a region size. In the present method named 'Moving Computational Domain Method', the whole of the computational domain including bodies inside moves in the physical space without the limit of region size. Since the whole of the grid of the computational domain moves according to the movement of the body, a flow solver of the method has to be constructed on the moving grid system and it is important for the flow solver to satisfy physical and geometric conservation laws simultaneously on moving grid. For this issue, the Moving-Grid Finite-Volume Method is employed as the flow solver. The present Moving Computational Domain Method makes it possible to simulate flow driven by any kind of motion of the body in any size of the region with satisfying physical and geometric conservation laws simultaneously. In this paper, the method is applied to the flow around a high-speed car passing through a hairpin curve. The distinctive flow field driven by the car at the hairpin curve has been demonstrated in detail. The results show the promising feature of the method.

  12. "You are so beautiful"*: behind women's attractiveness towards the biology of reproduction: a narrative review.

    PubMed

    Buggio, Laura; Vercellini, Paolo; Somigliana, Edgardo; Viganò, Paola; Frattaruolo, Maria Pina; Fedele, Luigi

    2012-10-01

    Female beauty has always attracted human beings. In particular, beauty has been interpreted in terms of reproductive potential and advantage in selection of mates. We have reviewed the recent literature on female facial and physical beauty with the objective of defining which parameters could influence female attractiveness. Symmetry, averageness, and sexual dimorphism with regards to facial beauty, as well as waist-to-hip ratio (WHR), breast size, and body mass index (BMI) for physical beauty, have been assessed. In current societies, it appears that facial attractiveness results from a mixture of symmetry and averageness of traits, high forehead and cheekbones, small nose and chin, full lips, thin eyebrows, and thick hair. A low WHR reliably characterized physical attractiveness, whereas inconsistencies have been observed in the evaluation of breast size and BMI. The importance of breast size appears to vary with time and sex of evaluators, whereas the impact of BMI is related to socio-economic conditions. The various hypotheses behind beauty and the role of attractiveness in mate choice and sexual selection are here described in terms of continuation of human species. Intriguing associations are emerging between features of attractiveness and some reproductive disorders, as both are substantially influenced by sex steroid hormones.

  13. Physical properties and surface/interface analysis of nanocrystalline WO3 films grown under variable oxygen gas flow rates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vemuri, R. S.; Carbjal-Franco, G.; Ferrer, D. A.

    2012-10-15

    Nanocrystalline WO3 films were grown by reactive magnetron sputter-deposition in a wide range of oxygen gas flow rates while keeping the deposition temperature fixed at 400 oC. The physical characteristics of WO3 films were evaluated using grazing incidence X-ray diffraction (GIXRD), X-ray reflectivity (XRR) and transmission electron microscopy (TEM) measurements. Physical characterization indicates that the thickness, grain size, and density of WO3 films are sensitive to the oxygen gas flow rate during deposition. XRD data indicates the formation of tetragonal WO3 films. The grain size increases from 21 to 25 nm with increasing oxygen gas flow rate to 65%, atmore » which point the grain size exhibits a decreasing trend to attain the lowest value of 15 nm at 100% oxygen. TEM analysis provides a model consisting of isotropic WO3 film (nanocrystalline)-SiO2 interface (amorphous)-Si(100) substrate. XRR simulations, which are based on this model, provide excellent agreement to the experimental data indicating that the normalized thickness of WO3 films decreases with the increasing oxygen gas flow rate. The density of WO3 films increases with increasing oxygen gas flow rate.« less

  14. A summary report on the search for current technologies and developers to develop depth profiling/physical parameter end effectors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nguyen, Q.H.

    1994-09-12

    This report documents the search strategies and results for available technologies and developers to develop tank waste depth profiling/physical parameter sensors. Sources searched include worldwide research reports, technical papers, journals, private industries, and work at Westinghouse Hanford Company (WHC) at Richland site. Tank waste physical parameters of interest are: abrasiveness, compressive strength, corrosiveness, density, pH, particle size/shape, porosity, radiation, settling velocity, shear strength, shear wave velocity, tensile strength, temperature, viscosity, and viscoelasticity. A list of related articles or sources for each physical parameters is provided.

  15. The influence of distance to school on the associations between active commuting and physical activity.

    PubMed

    Panter, Jenna; Jones, Andrew; Van Sluijs, Esther; Griffin, Simon

    2011-02-01

    The purpose of this cross-sectional study was to examine the associations between active commuting behavior, levels of physical activity and distance to school in 9-10 year old children. Participants were children (n = 1824) who took part in the SPEEDY study (Sport, Physical activity and Eating behavior: Environmental Determinants in Young people). For both boys and girls, significant positive associations were observed between walking to school and physical activity and moderate-to-vigorous physical activity during weekday journey times (8-9 am and 3-4 pm), and the size of association also became stronger with increasing distance from school. Promotion of active commuting to school might be an important way to increase levels of physical activity in school children.

  16. Does large body size in males evolve to facilitate forcible insemination? A study on garter snakes.

    PubMed

    Shine, Richard; Mason, Robert T

    2005-11-01

    A trend for larger males to obtain a disproportionately high number of matings, as occurs in many animal populations, typically is attributed either to female choice or success in male-male rivalry; an alternative mechanism, that larger males are better able to coercively inseminate females, has received much less attention. For example, previous studies on garter snakes (Thamnophis sirtalis parietalis) at communal dens in Manitoba have shown that the mating benefit to larger body size in males is due to size-dependent advantages in male-male rivalry. However, this previous work ignored the possibility that larger males may obtain more matings because of male-female interactions. In staged trials within outdoor arenas, larger body size enhanced male mating success regardless of whether a rival male was present. The mechanism involved was coercion rather than female choice, because mating occurred most often (and soonest) in females that were least able to resist courtship-induced hypoxic stress. Males do physically displace rivals from optimal positions in the mating ball, and larger males are better able to resist such displacement. Nonetheless, larger body size enhances male mating success even in the absence of such male-male interactions. Thus, even in mating systems where males compete physically and where larger body size confers a significant advantage in male-male competition, the actual selective force for larger body size in males may relate to forcible insemination of unreceptive females. Experimental studies are needed to determine whether the same situation occurs in other organisms in which body-size advantages have been attributed to male-male rather than male-female interactions.

  17. The evolution of helicopters

    NASA Astrophysics Data System (ADS)

    Chen, R.; Wen, C. Y.; Lorente, S.; Bejan, A.

    2016-07-01

    Here, we show that during their half-century history, helicopters have been evolving into geometrically similar architectures with surprisingly sharp correlations between dimensions, performance, and body size. For example, proportionalities emerge between body size, engine size, and the fuel load. Furthermore, the engine efficiency increases with the engine size, and the propeller radius is roughly the same as the length scale of the whole body. These trends are in accord with the constructal law, which accounts for the engine efficiency trend and the proportionality between "motor" size and body size in animals and vehicles. These body-size effects are qualitatively the same as those uncovered earlier for the evolution of aircraft. The present study adds to this theoretical body of research the evolutionary design of all technologies [A. Bejan, The Physics of Life: The Evolution of Everything (St. Martin's Press, New York, 2016)].

  18. Perception while watching movies: Effects of physical screen size and scene type

    PubMed Central

    Troscianko, Tom; Meese, Timothy S.; Hinde, Stephen

    2012-01-01

    Over the last decade, television screens and display monitors have increased in size considerably, but has this improved our televisual experience? Our working hypothesis was that the audiences adopt a general strategy that “bigger is better.” However, as our visual perceptions do not tap directly into basic retinal image properties such as retinal image size (C. A. Burbeck, 1987), we wondered whether object size itself might be an important factor. To test this, we needed a task that would tap into the subjective experiences of participants watching a movie on different-sized displays with the same retinal subtense. Our participants used a line bisection task to self-report their level of “presence” (i.e., their involvement with the movie) at several target locations that were probed in a 45-min section of the movie “The Good, The Bad, and The Ugly.” Measures of pupil dilation and reaction time to the probes were also obtained. In Experiment 1, we found that subjective ratings of presence increased with physical screen size, supporting our hypothesis. Face scenes also produced higher presence scores than landscape scenes for both screen sizes. In Experiment 2, reaction time and pupil dilation results showed the same trends as the presence ratings and pupil dilation correlated with presence ratings, providing some validation of the method. Overall, the results suggest that real-time measures of subjective presence might be a valuable tool for measuring audience experience for different types of (i) display and (ii) audiovisual material. PMID:23145293

  19. Exploring Explanations of Subglacial Bedform Sizes Using Statistical Models.

    PubMed

    Hillier, John K; Kougioumtzoglou, Ioannis A; Stokes, Chris R; Smith, Michael J; Clark, Chris D; Spagnolo, Matteo S

    2016-01-01

    Sediments beneath modern ice sheets exert a key control on their flow, but are largely inaccessible except through geophysics or boreholes. In contrast, palaeo-ice sheet beds are accessible, and typically characterised by numerous bedforms. However, the interaction between bedforms and ice flow is poorly constrained and it is not clear how bedform sizes might reflect ice flow conditions. To better understand this link we present a first exploration of a variety of statistical models to explain the size distribution of some common subglacial bedforms (i.e., drumlins, ribbed moraine, MSGL). By considering a range of models, constructed to reflect key aspects of the physical processes, it is possible to infer that the size distributions are most effectively explained when the dynamics of ice-water-sediment interaction associated with bedform growth is fundamentally random. A 'stochastic instability' (SI) model, which integrates random bedform growth and shrinking through time with exponential growth, is preferred and is consistent with other observations of palaeo-bedforms and geophysical surveys of active ice sheets. Furthermore, we give a proof-of-concept demonstration that our statistical approach can bridge the gap between geomorphological observations and physical models, directly linking measurable size-frequency parameters to properties of ice sheet flow (e.g., ice velocity). Moreover, statistically developing existing models as proposed allows quantitative predictions to be made about sizes, making the models testable; a first illustration of this is given for a hypothesised repeat geophysical survey of bedforms under active ice. Thus, we further demonstrate the potential of size-frequency distributions of subglacial bedforms to assist the elucidation of subglacial processes and better constrain ice sheet models.

  20. The Story of a Typical Atypical Graduate of the Physics Entrepreneurship Program at Case Western Reserve University

    NASA Astrophysics Data System (ADS)

    Luta, Adele

    2012-02-01

    An entrepreneurial perspective to life can lead to wearing a myriad of hats. Long gone is the stereotypical start-up role. Entrepreneurs now hold physics degrees and procure innovation when called upon. An alumni of the Physics Entrepreneurship Program, Adele Luta has spent the last 5 years at NASA developing an innovative approach to spacesuit sizing. Previously, she founded Eleda International consulting firm and is currently working with Adjuvat Biosciences, on a proprietary treatment pancreatic cancer.

  1. Mechanical Properties of the Solid Li-ion Conducting Electrolyte: Li0.33La0.57TiO3

    DTIC Science & Technology

    2012-01-01

    was determined from the mass and physical dimensions. In the second method, the bulk density was determined using the Archimedes method with water as...materials were respectively, 97 ± 4 and 95 ± 5 % (the large scatter is due to the small size of the sample) using the Archimedes method, 98 ± 0.2 and 95...SS using (1) Archimedes method, (2) physical measurement, and (3) image analysis Material Archimedes method Physical measurement Image analysis LLTO-SG

  2. Physical properties of five grain dust types.

    PubMed Central

    Parnell, C B; Jones, D D; Rutherford, R D; Goforth, K J

    1986-01-01

    Physical properties of grain dust derived from five grain types (soybean, rice, corn, wheat, and sorghum) were measured and reported. The grain dusts were obtained from dust collection systems of terminal grain handling facilities and were assumed to be representative of grain dust generated during the handling process. The physical properties reported were as follows: particle size distributions and surface area measurements using a Coulter Counter Model TAII; percent dust fractions less than 100 micron of whole dust; bulk density; particle density; and ash content. PMID:3709482

  3. Characterization of the Particle Size and Polydispersity of Dicumarol Using Solid-State NMR Spectroscopy.

    PubMed

    Dempah, Kassibla Elodie; Lubach, Joseph W; Munson, Eric J

    2017-03-06

    A variety of particle sizes of a model compound, dicumarol, were prepared and characterized in order to investigate the correlation between particle size and solid-state NMR (SSNMR) proton spin-lattice relaxation ( 1 H T 1 ) times. Conventional laser diffraction and scanning electron microscopy were used as particle size measurement techniques and showed crystalline dicumarol samples with sizes ranging from tens of micrometers to a few micrometers. Dicumarol samples were prepared using both bottom-up and top-down particle size control approaches, via antisolvent microprecipitation and cryogrinding. It was observed that smaller particles of dicumarol generally had shorter 1 H T 1 times than larger ones. Additionally, cryomilled particles had the shortest 1 H T 1 times encountered (8 s). SSNMR 1 H T 1 times of all the samples were measured and showed as-received dicumarol to have a T 1 of 1500 s, whereas the 1 H T 1 times of the precipitated samples ranged from 20 to 80 s, with no apparent change in the physical form of dicumarol. Physical mixtures of different sized particles were also analyzed to determine the effect of sample inhomogeneity on 1 H T 1 values. Mixtures of cryoground and as-received dicumarol were clearly inhomogeneous as they did not fit well to a one-component relaxation model, but could be fit much better to a two-component model with both fast-and slow-relaxing regimes. Results indicate that samples of crystalline dicumarol containing two significantly different particle size populations could be deconvoluted solely based on their differences in 1 H T 1 times. Relative populations of each particle size regime could also be approximated using two-component fitting models. Using NMR theory on spin diffusion as a reference, and taking into account the presence of crystal defects, a model for the correlation between the particle size of dicumarol and its 1 H T 1 time was proposed.

  4. SU-E-T-196: Comparative Analysis of Surface Dose Measurements Using MOSFET Detector and Dose Predicted by Eclipse - AAA with Varying Dose Calculation Grid Size

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Badkul, R; Nejaiman, S; Pokhrel, D

    2015-06-15

    Purpose: Skin dose can be the limiting factor and fairly common reason to interrupt the treatment, especially for treating head-and-neck with Intensity-modulated-radiation-therapy(IMRT) or Volumetrically-modulated - arc-therapy (VMAT) and breast with tangentially-directed-beams. Aim of this study was to investigate accuracy of near-surface dose predicted by Eclipse treatment-planning-system (TPS) using Anisotropic-Analytic Algorithm (AAA)with varying calculation grid-size and comparing with metal-oxide-semiconductor-field-effect-transistors(MOSFETs)measurements for a range of clinical-conditions (open-field,dynamic-wedge, physical-wedge, IMRT,VMAT). Methods: QUASAR™-Body-Phantom was used in this study with oval curved-surfaces to mimic breast, chest wall and head-and-neck sites.A CT-scan was obtained with five radio-opaque markers(ROM) placed on the surface of phantom to mimic themore » range of incident angles for measurements and dose prediction using 2mm slice thickness.At each ROM, small structure(1mmx2mm) were contoured to obtain mean-doses from TPS.Calculations were performed for open-field,dynamic-wedge,physical-wedge,IMRT and VMAT using Varian-21EX,6&15MV photons using twogrid-sizes:2.5mm and 1mm.Calibration checks were performed to ensure that MOSFETs response were within ±5%.Surface-doses were measured at five locations and compared with TPS calculations. Results: For 6MV: 2.5mm grid-size,mean calculated doses(MCD)were higher by 10%(±7.6),10%(±7.6),20%(±8.5),40%(±7.5),30%(±6.9) and for 1mm grid-size MCD were higher by 0%(±5.7),0%(±4.2),0%(±5.5),1.2%(±5.0),1.1% (±7.8) for open-field,dynamic-wedge,physical-wedge,IMRT,VMAT respectively.For 15MV: 2.5mm grid-size,MCD were higher by 30%(±14.6),30%(±14.6),30%(±14.0),40%(±11.0),30%(±3.5)and for 1mm grid-size MCD were higher by 10% (±10.6), 10%(±9.8),10%(±8.0),30%(±7.8),10%(±3.8) for open-field, dynamic-wedge, physical-wedge, IMRT, VMAT respectively.For 6MV, 86% and 56% of all measured values agreed better than ±20% for 1mm and 2.5mm grid-sizes respectively. For 18MV, 56% and 18% of all measured-values agreed better than ±20% for 1mm and 2.5mm grid-sizes respectively. Conclusion: Reliable Skin-dose calculations by TPS can be very difficult due to steep dose-gradient and inaccurate beam-modelling in buildup region.Our results showed that Eclipse over-estimates surface-dose.Impact of grid-size is also significant,surface-dose increased up to 40% from 1mm to 2.5mm,however, 1mm calculated-values closely agrees with measurements. Due to large uncertnities in skin-dose predictions from TPS, outmost caution must be exercised when skin dose is evaluated,a sufficiently smaller grid-size(1mm)can improve the accuracy and MOSFETs can be used for verification.« less

  5. Physical properties of organic particulate UV-absorbers used in sunscreens. I. Determination of particle size with fiber-optic quasi-elastic light scattering (FOQELS), disc centrifugation, and laser diffractometry.

    PubMed

    Herzog, Bernd; Katzenstein, Armin; Quass, Katja; Stehlin, Albert; Luther, Helmut

    2004-03-01

    In this study microparticles consisting of a benzotriazole derivative, which are used as absorbers for UV radiation in cosmetic sunscreens, were investigated. The particles were micronized in presence of a dispersing agent by means of a ball milling process. According to the energy input different particle sizes were produced in the range of 0.16 to 4 microm. The particle sizes obtained after different stages of the micronization process were measured using fiber-optic quasi-elastic light scattering (FOQELS), disc centrifugation, and laser diffractometry. All methods showed satisfactory agreement over the whole range of sizes. With the FOQELS technique the particle size distribution could be resolved to sizes well below 0.1 microm.

  6. Contest experience and body size affect different types of contest decisions.

    PubMed

    Chen, Yu-Ju; Hsu, Yuying

    2016-11-01

    This study examined the relative importance of contest experience and size differences to behavioral decisions over the course of contests. Using a mangrove rivulus fish, Kryptolebias marmoratus, we showed that although contest experience and size differences jointly determined contest outcomes, they affected contestants' interactions at different stages of contests. Contest experience affected behavioral decisions at earlier stages of contests, including the tendency and latency to launch attacks, the tendency to escalate contests into mutual attacks and the outcome of non-escalated contests. Once contests were escalated into mutual attacks, the degree of size difference affected the fish's persistence in escalation and chance of winning, but contest experience did not. These results support the hypothesis that contest experience modifies individuals' estimation of their fighting ability rather than their actual strength. Furthermore, (1) in contests between two naïve contestants, more than 60 % of fish that were 2-3 mm smaller than their opponent escalated the contest to physical fights, even though their larger opponents eventually won 92 % of escalated fights and (2) fish with a losing experience were very likely to retreat in the face of an opponent 2-3 mm smaller than them without escalating. The result that a 2-3 mm size advantage could not offset the influence of a losing experience on the tendency to escalate suggests that, as well as depending on body size, the fish's physical strength is influenced by other factors which require further investigation.

  7. Effect of subcutaneous Enoxaparin injection duration on bruising size in acute coronary syndrome patients.

    PubMed

    Dehghani, Khadije; Najari, Zahra; Dehghani, Hamideh

    2014-11-01

    Bruising is an unpleasant result of subcutaneous injection of Enoxaparin, which causes physical discomfort, limitation of injection site, patient's refusal of treatment, and distrust in nurses' ability. The application of techniques which reduce patients' fear, anxiety, and physical damage is one of the tasks of nurses. This clinical trial investigated the effect of duration of subcutaneous Enoxaparin injection on the bruising size in acute coronary syndrome patients. Seventy 35-75-year-old acute coronary syndrome patients hospitalized in Coronary Care Units were selected randomly. Each subject received 10- and 30-sec duration of injections by a single researcher on both sides of the abdomen in 12-h intervals. The bruising size was measured using a transparent millimeter measuring paper, 24 and 48 h after each injection. Data were gathered by a data recording form (demographic and measurements data) and analyzed by descriptive statistics and non-parametric tests through SPSS. Results showed that the mean bruising sizes at 24 h after 10- and 30-sec injection were 33.26 mm(2) (72.77) and 48.96 mm(2) (99.91), respectively, and at 48 h were 15.61 mm(2) (142.02) and 52.48 mm(2) (143), respectively. There was no significant relationship between the two techniques (P > 0.05), although the effect of age on bruising size was significant (P = 0.01). According to the findings of the present study, length of Enoxaparin subcutaneous injection has no effect on the bruising size.

  8. Physical perceptions and self-concept in athletes with muscle dysmorphia symptoms.

    PubMed

    González-Martí, Irene; Fernández Bustos, Juan Gregorio; Hernández-Martínez, Andrea; Contreras Jordán, Onofre Ricardo

    2014-01-01

    Individuals affected by Muscle Dysmorphia (MD; body image disorder based on the sub estimation of muscle size), practice weightlifting in order to alleviate their muscular dissatisfaction. Although physical activity is associated with increased physical self-perception, we assume that this was not reproduced in full in people with MD. The study sample consisted of 734 weightlifters and bodybuilders, 562 men and 172 women, who completed the Escala de Satisfacción Muscular, the Physical Self-Concept Questionnaire, and from whom measures of body fat and Fat -Free Mass Index (FFMI) were obtained. The results showed that people suffering from MD symptoms, overall, have poorer physical self-concept perceptions (F = 18.46 - 34.77, p < .01).

  9. Age-related structural alterations in human skeletal muscle fibers and mitochondria are sex specific: relationship to single-fiber function.

    PubMed

    Callahan, Damien M; Bedrin, Nicholas G; Subramanian, Meenakumari; Berking, James; Ades, Philip A; Toth, Michael J; Miller, Mark S

    2014-06-15

    Age-related loss of skeletal muscle mass and function is implicated in the development of disease and physical disability. However, little is known about how age affects skeletal muscle structure at the cellular and ultrastructural levels or how such alterations impact function. Thus we examined skeletal muscle structure at the tissue, cellular, and myofibrillar levels in young (21-35 yr) and older (65-75 yr) male and female volunteers, matched for habitual physical activity level. Older adults had smaller whole muscle tissue cross-sectional areas (CSAs) and mass. At the cellular level, older adults had reduced CSAs in myosin heavy chain II (MHC II) fibers, with no differences in MHC I fibers. In MHC II fibers, older men tended to have fewer fibers with large CSAs, while older women showed reduced fiber size across the CSA range. Older adults showed a decrease in intermyofibrillar mitochondrial size; however, the age effect was driven primarily by women (i.e., age by sex interaction effect). Mitochondrial size was inversely and directly related to isometric tension and myosin-actin cross-bridge kinetics, respectively. Notably, there were no intermyofibrillar or subsarcolemmal mitochondrial fractional content or myofilament ultrastructural differences in the activity-matched young and older adults. Collectively, our results indicate age-related reductions in whole muscle size do not vary by sex. However, age-related structural alterations at the cellular and subcellular levels are different between the sexes and may contribute to different functional phenotypes in ways that modulate sex-specific reductions in physical capacity with age. Copyright © 2014 the American Physiological Society.

  10. On the utilization of hydrological modelling for road drainage design under climate and land use change.

    PubMed

    Kalantari, Zahra; Briel, Annemarie; Lyon, Steve W; Olofsson, Bo; Folkeson, Lennart

    2014-03-15

    Road drainage structures are often designed using methods that do not consider process-based representations of a landscape's hydrological response. This may create inadequately sized structures as coupled land cover and climate changes can lead to an amplified hydrological response. This study aims to quantify potential increases of runoff in response to future extreme rain events in a 61 km(2) catchment (40% forested) in southwest Sweden using a physically-based hydrological modelling approach. We simulate peak discharge and water level (stage) at two types of pipe bridges and one culvert, both of which are commonly used at Swedish road/stream intersections, under combined forest clear-cutting and future climate scenarios for 2050 and 2100. The frequency of changes in peak flow and water level varies with time (seasonality) and storm size. These changes indicate that the magnitude of peak flow and the runoff response are highly correlated to season rather than storm size. In all scenarios considered, the dimensions of the current culvert are insufficient to handle the increase in water level estimated using a physically-based modelling approach. It also appears that the water level at the pipe bridges changes differently depending on the size and timing of the storm events. The findings of the present study and the approach put forward should be considered when planning investigations on and maintenance for areas at risk of high water flows. In addition, the research highlights the utility of physically-based hydrological models to identify the appropriateness of road drainage structure dimensioning. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Traffic-induced changes and processes in forest road aggregate particle-size distributions

    Treesearch

    Hakjun Rhee; James Fridley; Deborah Page-Dumroese

    2018-01-01

    Traffic can alter forest road aggregate material in various ways, such as by crushing, mixing it with subgrade material, and sweeping large-size, loose particles (gravel) toward the outside of the road. Understanding the changes and physical processes of the aggregate is essential to mitigate sediment production from forest roads and reduce road maintenance efforts. We...

  12. Selected properties of particleboard panels manufactured from rice straws of different geometries

    Treesearch

    Xianjun Li; Zhiyong Cai; Jerrold E. Winandy; Altaf H. Basta

    2010-01-01

    The objective is to evaluate the primary mechanical and physical properties of particleboard made from hammer-milled rice straw particles of six different categories and two types of resins. The results show the performance of straw particleboards is highly dependent upon the straw particle size controlled by the opening size of the perforated plate inside the hammer-...

  13. Children's Basketball Performance with Regulation and Junior-Sized Basketballs.

    ERIC Educational Resources Information Center

    Haywood, Kathleen M.

    The smaller size and lower strength level of children may indicate that adaptations of sport-type games, such as basketball, are necessary to maximize skill performance. Children between the ages of 9.0 and 12.7 years were given two subtests of the Alliance for Health, Physical Education, and Recreation Skills Test, the Speed Pass and Front Shot.…

  14. The Relationship with Balance, Foot Posture, and Foot Size in School of Physical Education and Sports Students

    ERIC Educational Resources Information Center

    Irez, Gonul Babayigit

    2014-01-01

    The aim of this study is to investigate the relationship of foot posture and foot size with balance. A hundred and thirteen healthy volunteers were recruited from undergraduate students (Male = 74, Female = 37, age range 18-22). The Foot Posture Index (FPI-6), anthropometric measurements, dynamic balance and static balance measurements were done…

  15. Pediatric Anthropometry

    NASA Astrophysics Data System (ADS)

    Klinich, Kathleen D.; Reed, Matthew P.

    Anthropometry is the measurement of human size, shape, and physical capabilities. Most pediatric anthropometry data are gathered to describe child growth patterns, but data on body size, mass distribution, range of motion, and posture are used to develop crash test dummies and computational models of child occupants. Pediatric anthropometry data are also used to determine child restraint dimensions, so they will accommodate the applicable population of child occupants.

  16. Fractal Features of Soil Particle Size Distribution Under Different Plant Communities in the Forested Region of Mountain Yimeng, China

    USDA-ARS?s Scientific Manuscript database

    In order to explore the effect of changes in plant communities and land use on soil properties, as a result of anthropogenic disturbances, we apply the theory of fractals and soil physics as a means to better quantify changes in particle-size distribution (PSD) and soil porosity. Fractal dimension a...

  17. Meta-Analysis of the Effect of Exercise Programs for Individuals with Intellectual Disabilities

    ERIC Educational Resources Information Center

    Shin, In-Soo; Park, Eun-Young

    2012-01-01

    The purpose of this study was to examine the effects of physical exercise programs on individuals with intellectual disabilities (ID). This meta-analysis analyzed 67 effect sizes and 14 studies and calculated the standardized mean difference in effect size. The unit of analysis for overall effects was the study, and the sub-group analysis focused…

  18. Diet- and Body Size-related Attitudes and Behaviors Associated with Vitamin Supplement Use in a Representative Sample of Fourth-grade Students in Texas

    USDA-ARS?s Scientific Manuscript database

    The objective of this research was to examine diet- and body size-related attitudes and behaviors associated with supplement use in a representative sample of fourth-grade students in Texas. The research design consisted of cross-sectional data from the School Physical Activity and Nutrition study, ...

  19. Computationally-Guided Synthetic Control over Pore Size in Isostructural Porous Organic Cages

    DOE PAGES

    Slater, Anna G.; Reiss, Paul S.; Pulido, Angeles; ...

    2017-06-20

    The physical properties of 3-D porous solids are defined by their molecular geometry. Hence, precise control of pore size, pore shape, and pore connectivity are needed to tailor them for specific applications. However, for porous molecular crystals, the modification of pore size by adding pore-blocking groups can also affect crystal packing in an unpredictable way. This precludes strategies adopted for isoreticular metal-organic frameworks, where addition of a small group, such as a methyl group, does not affect the basic framework topology. Here, we narrow the pore size of a cage molecule, CC3, in a systematic way by introducing methyl groupsmore » into the cage windows. Computational crystal structure prediction was used to anticipate the packing preferences of two homochiral methylated cages, CC14-R and CC15-R, and to assess the structure-energy landscape of a CC15-R/CC3-S cocrystal, designed such that both component cages could be directed to pack with a 3-D, interconnected pore structure. The experimental gas sorption properties of these three cage systems agree well with physical properties predicted by computational energy-structure-function maps.« less

  20. Stretched exponential distributions in nature and economy: ``fat tails'' with characteristic scales

    NASA Astrophysics Data System (ADS)

    Laherrère, J.; Sornette, D.

    1998-04-01

    To account quantitatively for many reported "natural" fat tail distributions in Nature and Economy, we propose the stretched exponential family as a complement to the often used power law distributions. It has many advantages, among which to be economical with only two adjustable parameters with clear physical interpretation. Furthermore, it derives from a simple and generic mechanism in terms of multiplicative processes. We show that stretched exponentials describe very well the distributions of radio and light emissions from galaxies, of US GOM OCS oilfield reserve sizes, of World, US and French agglomeration sizes, of country population sizes, of daily Forex US-Mark and Franc-Mark price variations, of Vostok (near the south pole) temperature variations over the last 400 000 years, of the Raup-Sepkoski's kill curve and of citations of the most cited physicists in the world. We also discuss its potential for the distribution of earthquake sizes and fault displacements. We suggest physical interpretations of the parameters and provide a short toolkit of the statistical properties of the stretched exponentials. We also provide a comparison with other distributions, such as the shifted linear fractal, the log-normal and the recently introduced parabolic fractal distributions.

  1. Effect of different sizes of palm oil fuel ash (POFA) towards physical properties of modified bitumen

    NASA Astrophysics Data System (ADS)

    Raja Zulkefli, R. N. A.; Yaacob, H.; Putra Jaya, R.; Warid, M. N. M.; Hassan, N.; Hainin, M. R.; Idham, M. K.

    2018-04-01

    In the past decades, numerous numbers of studies have been carried out to find ways enhancing properties of bitumen. Other than using polymer, agricultural waste such as palm oil fuel ash (POFA) is one of the waste products that can be used to modify bitumen. In this study, the physical and rheological properties of POFA modified bitumen were examined based on different grinding hour and different percentage of POFA. The bitumen were mixed with different percentages of POFA (0, 5 and 7%) which passed through 0.075 mm sieve and grinded at different period (1 and 4 hour). The samples were then tested and compared to conventional bitumen. From TEM results, POFA grinded at 1 hour have sizes between 3-7 µm while POFA grinded for 4 hours have finer sizes between 500 nm to 3 µm. The results showed that fineness of POFA affect properties of bitumen significantly. Decreasing in penetration value and decreasing in softening temperature indicates that the modified bitumen becomes harder than conventional bitumen. Modified bitumen gives best results when added with 7% POFA sizes of 500 nm to 3 µm compared to 3 to 7 µm.

  2. Computationally-Guided Synthetic Control over Pore Size in Isostructural Porous Organic Cages

    PubMed Central

    2017-01-01

    The physical properties of 3-D porous solids are defined by their molecular geometry. Hence, precise control of pore size, pore shape, and pore connectivity are needed to tailor them for specific applications. However, for porous molecular crystals, the modification of pore size by adding pore-blocking groups can also affect crystal packing in an unpredictable way. This precludes strategies adopted for isoreticular metal–organic frameworks, where addition of a small group, such as a methyl group, does not affect the basic framework topology. Here, we narrow the pore size of a cage molecule, CC3, in a systematic way by introducing methyl groups into the cage windows. Computational crystal structure prediction was used to anticipate the packing preferences of two homochiral methylated cages, CC14-R and CC15-R, and to assess the structure–energy landscape of a CC15-R/CC3-S cocrystal, designed such that both component cages could be directed to pack with a 3-D, interconnected pore structure. The experimental gas sorption properties of these three cage systems agree well with physical properties predicted by computational energy–structure–function maps. PMID:28776015

  3. Computationally-Guided Synthetic Control over Pore Size in Isostructural Porous Organic Cages

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slater, Anna G.; Reiss, Paul S.; Pulido, Angeles

    The physical properties of 3-D porous solids are defined by their molecular geometry. Hence, precise control of pore size, pore shape, and pore connectivity are needed to tailor them for specific applications. However, for porous molecular crystals, the modification of pore size by adding pore-blocking groups can also affect crystal packing in an unpredictable way. This precludes strategies adopted for isoreticular metal-organic frameworks, where addition of a small group, such as a methyl group, does not affect the basic framework topology. Here, we narrow the pore size of a cage molecule, CC3, in a systematic way by introducing methyl groupsmore » into the cage windows. Computational crystal structure prediction was used to anticipate the packing preferences of two homochiral methylated cages, CC14-R and CC15-R, and to assess the structure-energy landscape of a CC15-R/CC3-S cocrystal, designed such that both component cages could be directed to pack with a 3-D, interconnected pore structure. The experimental gas sorption properties of these three cage systems agree well with physical properties predicted by computational energy-structure-function maps.« less

  4. Methods to control ectomycorrhizal colonization: effectiveness of chemical and physical barriers.

    PubMed

    Teste, François P; Karst, Justine; Jones, Melanie D; Simard, Suzanne W; Durall, Daniel M

    2006-12-01

    We conducted greenhouse experiments using Douglas-fir (Pseudotsuga menziesii var. glauca) seedlings where chemical methods (fungicides) were used to prevent ectomycorrhizal colonization of single seedlings or physical methods (mesh barriers) were used to prevent formation of mycorrhizal connections between neighboring seedlings. These methods were chosen for their ease of application in the field. We applied the fungicides, Topas (nonspecific) and Senator (ascomycete specific), separately and in combination at different concentrations and application frequencies to seedlings grown in unsterilized forest soils. Additionally, we assessed the ability of hyphae to penetrate mesh barriers of various pore sizes (0.2, 1, 20, and 500 microm) to form mycorrhizas on roots of neighboring seedlings. Ectomycorrhizal colonization was reduced by approximately 55% with the application of Topas at 0.5 g l(-1). Meshes with pore sizes of 0.2 and 1 microm were effective in preventing the formation of mycorrhizas via hyphal growth across the mesh barriers. Hence, meshes in this range of pore sizes could also be used to prevent the formation of common mycorrhizal networks in the field. Depending on the ecological question of interest, Topas or the employment of mesh with pore sizes <1 microm are suitable for restricting mycorrhization in the field.

  5. Novel cryomilled physically cross-linked biodegradable hydrogel microparticles as carriers for inhalation therapy.

    PubMed

    El-Sherbiny, I M; Smyth, H D C

    2010-01-01

    In this study, novel biodegradable physically cross-linked hydrogel microparticles were developed and evaluated in-vitro as potential carriers for inhalation therapy. These hydrogel microparticles were prepared to be respirable (desired aerodynamic size) when dry and also designed to avoid the macrophage uptake (attain large swollen size once deposited in lung). The swellable microparticles, prepared using cryomilling, were based on Pluronic® F-108 in combination with PEG grafted onto both chitosan (Cs) and its N-phthaloyl derivative (NPHCs). Polymers synthesized in the study were characterized using EA, FTIR, 2D-XRD and DSC. Morphology, particle size, density, biodegradation and moisture content of the microparticles were quantified. Swelling characteristics for both drug-free and drug-loaded microparticles showed excellent size increases (between 700-1300%) and the release profiles indicated sustained release could be achieved for up to 20 days. The respirable microparticles showed drug loading efficiency up to 92%. The enzymatic degradation of developed microparticles started within the first hour and only ∼10% weights were remaining after 10 days. In conclusion, these respirable microparticles demonstrated promising in-vitro performance for potential sustained release vectors in pulmonary drug delivery.

  6. Computed Tomography to Estimate the Representative Elementary Area for Soil Porosity Measurements

    PubMed Central

    Borges, Jaqueline Aparecida Ribaski; Pires, Luiz Fernando; Belmont Pereira, André

    2012-01-01

    Computed tomography (CT) is a technique that provides images of different solid and porous materials. CT could be an ideal tool to study representative sizes of soil samples because of the noninvasive characteristic of this technique. The scrutiny of such representative elementary sizes (RESs) has been the target of attention of many researchers related to soil physics field owing to the strong relationship between physical properties and size of the soil sample. In the current work, data from gamma-ray CT were used to assess RES in measurements of soil porosity (ϕ). For statistical analysis, a study on the full width at a half maximum (FWHM) of the adjustment of distribution of ϕ at different areas (1.2 to 1162.8 mm2) selected inside of tomographic images was proposed herein. The results obtained point out that samples with a section area corresponding to at least 882.1 mm2 were the ones that provided representative values of ϕ for the studied Brazilian tropical soil. PMID:22666133

  7. Fiber atrophy and hypertrophy in skeletal muscles of late middle-aged Fischer 344 x Brown Norway F1-hybrid rats.

    PubMed

    Hepple, Russell T; Ross, Karen D; Rempfer, Amanda B

    2004-02-01

    We examined young adult and late middle-aged male rats to test the hypothesis that gastrocnemius (a locomotor muscle) demonstrates reduced fiber size with aging, whereas soleus (a postural muscle) demonstrates atrophy of some fibers and compensatory hypertrophy in other fibers. Although body mass was greater in late middle-aged animals, mass was reduced in gastrocnemius but not soleus muscle. In another group of animals, physical activity was reduced by 34% in late middle-aged animals. Whereas mean fiber size was lower in gastrocnemius of late middle-aged animals, it was not different in soleus. Histograms revealed atrophied fibers (/=8000 micro m(2)) in soleus with aging. Atrophied fibers often demonstrated no subsarcolemmal mitochondrial staining, suggesting denervation, whereas hypertrophied fibers often demonstrated cytochrome oxidase deficiency, suggesting mitochondrial dysfunction. These results underscore the divergent influences (e.g., physical inactivity, denervation, mitochondrial dysfunction) affecting fiber size with aging.

  8. Cryoprotectant choice and analyses of freeze-drying drug suspension of nanoparticles with functional stabilisers.

    PubMed

    Wang, Lulu; Ma, Yingying; Gu, Yu; Liu, Yangyang; Zhao, Juan; Yan, Beibei; Wang, Yancai

    2018-04-19

    Freeze-drying is an effective way to improve long-term physical stability of nanosuspension in drug delivery applications. Nanosuspension also known as suspension of nanoparticles. In this study, the effect of freeze-drying with different cryoprotectants on the physicochemical characteristics of resveratrol (RSV) nanosuspension and quercetin (QUE) nanosuspension was evaluated. D-α-tocopheryl polyethylene glycol succinate (TPGS) and folate-modified distearoylphosphatidyl ethanolamine-polyethylene glycol (DSPE-PEG-FA) were selected as functional stabilisers formulated nanosuspension which were prepared by anti-solvent precipitation method. RSV nanoparticle size and QUE nanoparticle size were about 210 and 110 nm, respectively. The AFM and TEM results of nanosuspension showed uniform and irregular shape particles. After freeze-drying, the optimal concentration of four cryoprotectants was determined by the particle size of re-dispersed nanoparticles. The dissolution profile of drug nanoparticle significantly showed approximately at a 6-8-fold increase dissolution rate. Moreover, TPGS and DSPE-PEG-FA stabilised RSV nanosuspension and QUE nanosuspension samples showed better effect on long-term physical stability.

  9. Bias correction factors for near-Earth asteroids

    NASA Technical Reports Server (NTRS)

    Benedix, Gretchen K.; Mcfadden, Lucy Ann; Morrow, Esther M.; Fomenkova, Marina N.

    1992-01-01

    Knowledge of the population size and physical characteristics (albedo, size, and rotation rate) of near-Earth asteroids (NEA's) is biased by observational selection effects which are functions of the population's intrinsic properties and the size of the telescope, detector sensitivity, and search strategy used. The NEA population is modeled in terms of orbital and physical elements: a, e, i, omega, Omega, M, albedo, and diameter, and an asteroid search program is simulated using actual telescope pointings of right ascension, declination, date, and time. The position of each object in the model population is calculated at the date and time of each telescope pointing. The program tests to see if that object is within the field of view (FOV = 8.75 degrees) of the telescope and above the limiting magnitude (V = +1.65) of the film. The effect of the starting population on the outcome of the simulation's discoveries is compared to the actual discoveries in order to define a most probable starting population.

  10. SlimCS—compact low aspect ratio DEMO reactor with reduced-size central solenoid

    NASA Astrophysics Data System (ADS)

    Tobita, K.; Nishio, S.; Sato, M.; Sakurai, S.; Hayashi, T.; Shibama, Y. K.; Isono, T.; Enoeda, M.; Nakamura, H.; Sato, S.; Ezato, K.; Hayashi, T.; Hirose, T.; Ide, S.; Inoue, T.; Kamada, Y.; Kawamura, Y.; Kawashima, H.; Koizumi, N.; Kurita, G.; Nakamura, Y.; Mouri, K.; Nishitani, T.; Ohmori, J.; Oyama, N.; Sakamoto, K.; Suzuki, S.; Suzuki, T.; Tanigawa, H.; Tsuchiya, K.; Tsuru, D.

    2007-08-01

    The concept for a compact DEMO reactor named 'SlimCS' is presented. Distinctive features of the concept are low aspect ratio (A = 2.6) and use of a reduced-size centre solenoid (CS) which has the function of plasma shaping rather than poloidal flux supply. The reduced-size CS enables us to introduce a thin toroidal field coil system which contributes to reducing the weight and perhaps lessening the construction cost. Low-A has merits of vertical stability for high elongation (κ) and high normalized beta (βN), which leads to a high power density with reasonable physics requirements. This is because high κ facilitates high nGW (because of an increase in Ip), which allows efficient use of the capacity of high βN. From an engineering aspect, low-A may ensure ease in designing blanket modules robust to electromagnetic forces acting on disruptions. Thus, a superconducting low-A tokamak reactor such as SlimCS can be a promising DEMO concept with physics and engineering advantages.

  11. Study of the role of bran water binding and the steric hindrance by bran in straight dough bread making.

    PubMed

    Hemdane, S; Langenaeken, N A; Jacobs, P J; Verspreet, J; Delcour, J A; Courtin, C M

    2018-07-01

    This study investigates the effect of the physical presence and water binding of wheat bran during bread making, and the possible mechanisms behind this effect. Regular bran, pericarp-enriched bran and synthetic bran-like particles with different water binding capacities and particle sizes were used. Incorporation of regular and pericarp-enriched bran in dough (15% dm) led to a lower oven rise than the control dough. Bread volumes decreased with 11% and 30%, respectively. Dough with synthetic bran, having a low water binding capacity, displayed a near to normal leavening and oven rise and resulted in a bread volume decrease of only 5% compared to the control. Particle size reduction of regular bran and synthetic bran to an average size of 200 µm did not affect final bread quality. Results indicate that water binding by bran affects bread quality the most, whereas steric hindrance by physical presence of bran particles is less determinative. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Multi-Parameter Scattering Sensor and Methods

    NASA Technical Reports Server (NTRS)

    Greenberg, Paul S. (Inventor); Fischer, David G. (Inventor)

    2016-01-01

    Methods, detectors and systems detect particles and/or measure particle properties. According to one embodiment, a detector for detecting particles comprises: a sensor for receiving radiation scattered by an ensemble of particles; and a processor for determining a physical parameter for the detector, or an optimal detection angle or a bound for an optimal detection angle, for measuring at least one moment or integrated moment of the ensemble of particles, the physical parameter, or detection angle, or detection angle bound being determined based on one or more of properties (a) and/or (b) and/or (c) and/or (d) or ranges for one or more of properties (a) and/or (b) and/or (c) and/or (d), wherein (a)-(d) are the following: (a) is a wavelength of light incident on the particles, (b) is a count median diameter or other characteristic size parameter of the particle size distribution, (c) is a standard deviation or other characteristic width parameter of the particle size distribution, and (d) is a refractive index of particles.

  13. A randomised controlled trial of adjunctive yoga and adjunctive physical exercise training for cognitive dysfunction in schizophrenia.

    PubMed

    Bhatia, Triptish; Mazumdar, Sati; Wood, Joel; He, Fanyin; Gur, Raquel E; Gur, Ruben C; Nimgaonkar, Vishwajit L; Deshpande, Smita N

    2017-04-01

    Yoga and physical exercise have been used as adjunctive intervention for cognitive dysfunction in schizophrenia (SZ), but controlled comparisons are lacking. Aims A single-blind randomised controlled trial was designed to evaluate whether yoga training or physical exercise training enhance cognitive functions in SZ, based on a prior pilot study. Consenting, clinically stable, adult outpatients with SZ (n=286) completed baseline assessments and were randomised to treatment as usual (TAU), supervised yoga training with TAU (YT) or supervised physical exercise training with TAU (PE). Based on the pilot study, the primary outcome measure was speed index for the cognitive domain of 'attention' in the Penn computerised neurocognitive battery. Using mixed models and contrasts, cognitive functions at baseline, 21 days (end of training), 3 and 6 months post-training were evaluated with intention-to-treat paradigm. Speed index of attention domain in the YT group showed greater improvement than PE at 6 months follow-up (p<0.036, effect size 0.51). In the PE group, 'accuracy index of attention domain showed greater improvement than TAU alone at 6-month follow-up (p<0.025, effect size 0.61). For several other cognitive domains, significant improvements were observed with YT or PE compared with TAU alone (p<0.05, effect sizes 0.30-1.97). Both YT and PE improved attention and additional cognitive domains well past the training period, supporting our prior reported beneficial effect of YT on speed index of attention domain. As adjuncts, YT or PE can benefit individuals with SZ.

  14. Geophysical Parameter Estimation of Near Surface Materials Using Nuclear Magnetic Resonance

    NASA Astrophysics Data System (ADS)

    Keating, K.

    2017-12-01

    Proton nuclear magnetic resonance (NMR), a mature geophysical technology used in petroleum applications, has recently emerged as a promising tool for hydrogeophysicists. The NMR measurement, which can be made in the laboratory, in boreholes, and using a surface based instrument, are unique in that it is directly sensitive to water, via the initial signal magnitude, and thus provides a robust estimate of water content. In the petroleum industry rock physics models have been established that relate NMR relaxation times to pore size distributions and permeability. These models are often applied directly for hydrogeophysical applications, despite differences in the material in these two environments (e.g., unconsolidated versus consolidated, and mineral content). Furthermore, the rock physics models linking NMR relaxation times to pore size distributions do not account for partially saturated systems that are important for understanding flow in the vadose zone. In our research, we are developing and refining quantitative rock physics models that relate NMR parameters to hydrogeological parameters. Here we highlight the limitations of directly applying established rock physics models to estimate hydrogeological parameters from NMR measurements, and show some of the successes we have had in model improvement. Using examples drawn from both laboratory and field measurements, we focus on the use of NMR in partial saturated systems to estimate water content, pore-size distributions, and the water retention curve. Despite the challenges in interpreting the measurements, valuable information about hydrogeological parameters can be obtained from NMR relaxation data, and we conclude by outlining pathways for improving the interpretation of NMR data for hydrogeophysical investigations.

  15. The role of social relationships in the link between olfactory dysfunction and mortality.

    PubMed

    Leschak, Carrianne J; Eisenberger, Naomi I

    2018-01-01

    Recent work suggests that olfactory dysfunction is a strong predictor of five-year mortality in older adults. Based on past work showing: 1) that olfactory dysfunction impairs social functioning and 2) that social ties are linked with mortality, the current work explored whether impairments in social life mediated the relationship between olfactory dysfunction and mortality. Additionally, based on work showing gender differences in the social consequences of olfactory dysfunction, gender was assessed as a potential moderator of this association. Social network size mediated the olfactory-mortality link for females. To probe what feature of social networks was driving this effect, we investigated two subcomponents of social life: emotional closeness (e.g., perceived social support, loneliness) and physical closeness (e.g., physical contact, in-person socializing with others). Physical closeness significantly mediated the olfactory-mortality link for females, even after controlling for social network size. Emotional closeness did not mediate this link. Possible mechanisms underlying this relationship are discussed.

  16. Are there laws of genome evolution?

    PubMed

    Koonin, Eugene V

    2011-08-01

    Research in quantitative evolutionary genomics and systems biology led to the discovery of several universal regularities connecting genomic and molecular phenomic variables. These universals include the log-normal distribution of the evolutionary rates of orthologous genes; the power law-like distributions of paralogous family size and node degree in various biological networks; the negative correlation between a gene's sequence evolution rate and expression level; and differential scaling of functional classes of genes with genome size. The universals of genome evolution can be accounted for by simple mathematical models similar to those used in statistical physics, such as the birth-death-innovation model. These models do not explicitly incorporate selection; therefore, the observed universal regularities do not appear to be shaped by selection but rather are emergent properties of gene ensembles. Although a complete physical theory of evolutionary biology is inconceivable, the universals of genome evolution might qualify as "laws of evolutionary genomics" in the same sense "law" is understood in modern physics.

  17. Thermal Decomposition Synthesis of Iron Oxide Nanoparticles with Diminished Magnetic Dead Layer by Controlled Addition of Oxygen.

    PubMed

    Unni, Mythreyi; Uhl, Amanda M; Savliwala, Shehaab; Savitzky, Benjamin H; Dhavalikar, Rohan; Garraud, Nicolas; Arnold, David P; Kourkoutis, Lena F; Andrew, Jennifer S; Rinaldi, Carlos

    2017-02-28

    Decades of research focused on size and shape control of iron oxide nanoparticles have led to methods of synthesis that afford excellent control over physical size and shape but comparatively poor control over magnetic properties. Popular synthesis methods based on thermal decomposition of organometallic precursors in the absence of oxygen have yielded particles with mixed iron oxide phases, crystal defects, and poorer than expected magnetic properties, including the existence of a thick "magnetically dead layer" experimentally evidenced by a magnetic diameter significantly smaller than the physical diameter. Here, we show how single-crystalline iron oxide nanoparticles with few defects and similar physical and magetic diameter distributions can be obtained by introducing molecular oxygen as one of the reactive species in the thermal decomposition synthesis. This is achieved without the need for any postsynthesis oxidation or thermal annealing. These results address a significant challenge in the synthesis of nanoparticles with predictable magnetic properties and could lead to advances in applications of magnetic nanoparticles.

  18. Interfacial mixing in high energy-density matter with a multiphysics kinetic model

    NASA Astrophysics Data System (ADS)

    Haack, Jeff; Hauck, Cory; Murillo, Michael

    2017-10-01

    We have extended a recently-developed multispecies, multitemperature BGK model to include multiphysics capability that allows modeling of a wider range of plasma conditions. In particular, we have extended the model to describe one spatial dimension, and included a multispecies atomic ionization model, accurate collision physics across coupling regimes, self-consistent electric fields, and degeneracy in the electronic screening. We apply the new model to a warm dense matter scenario in which the ablator-fuel interface of an inertial confinement fusion target is heated, similar to a recent molecular dynamics study, but for larger length and time scales and for much higher temperatures. From our numerical results we are able to explore a variety of phenomena, including hydrogen jetting, kinetic effects (non-Maxwellian and anisotropic distributions), plasma physics (size, persistence and role of electric fields) and transport (relative sizes of Fickean diffision, electrodiffusion and barodiffusion). As compared with the recent molecular dynamics work the kinetic model greatly extends the accessible physical domains we are able to model.

  19. Nuclear Physics and Lattice QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beane, Silas

    2003-11-01

    Impressive progress is currently being made in computing properties and interac- tions of the low-lying hadrons using lattice QCD. However, cost limitations will, for the foreseeable future, necessitate the use of quark masses, Mq, that are signif- icantly larger than those of nature, lattice spacings, a, that are not significantly smaller than the physical scale of interest, and lattice sizes, L, that are not sig- nificantly larger than the physical scale of interest. Extrapolations in the quark masses, lattice spacing and lattice volume are therefore required. The hierarchy of mass scales is: L 1 j Mq j â ºC jmore » a 1 . The appropriate EFT for incorporating the light quark masses, the finite lattice spacing and the lattice size into hadronic observables is C-PT, which provides systematic expansions in the small parame- ters e m L, 1/ Lâ ºC, p/â ºC, Mq/â ºC and aâ ºC . The lattice introduces other unphysical scales as well. Lattice QCD quarks will increasingly be artificially separated« less

  20. Accretion-induced variability links young stellar objects, white dwarfs, and black holes.

    PubMed

    Scaringi, Simone; Maccarone, Thomas J; Körding, Elmar; Knigge, Christian; Vaughan, Simon; Marsh, Thomas R; Aranzana, Ester; Dhillon, Vikram S; Barros, Susana C C

    2015-10-01

    The central engines of disc-accreting stellar-mass black holes appear to be scaled down versions of the supermassive black holes that power active galactic nuclei. However, if the physics of accretion is universal, it should also be possible to extend this scaling to other types of accreting systems, irrespective of accretor mass, size, or type. We examine new observations, obtained with Kepler/K2 and ULTRACAM, regarding accreting white dwarfs and young stellar objects. Every object in the sample displays the same linear correlation between the brightness of the source and its amplitude of variability (rms-flux relation) and obeys the same quantitative scaling relation as stellar-mass black holes and active galactic nuclei. We also show that the most important parameter in this scaling relation is the physical size of the accreting object. This establishes the universality of accretion physics from proto-stars still in the star-forming process to the supermassive black holes at the centers of galaxies.

  1. Accretion-induced variability links young stellar objects, white dwarfs, and black holes

    PubMed Central

    Scaringi, Simone; Maccarone, Thomas J.; Körding, Elmar; Knigge, Christian; Vaughan, Simon; Marsh, Thomas R.; Aranzana, Ester; Dhillon, Vikram S.; Barros, Susana C. C.

    2015-01-01

    The central engines of disc-accreting stellar-mass black holes appear to be scaled down versions of the supermassive black holes that power active galactic nuclei. However, if the physics of accretion is universal, it should also be possible to extend this scaling to other types of accreting systems, irrespective of accretor mass, size, or type. We examine new observations, obtained with Kepler/K2 and ULTRACAM, regarding accreting white dwarfs and young stellar objects. Every object in the sample displays the same linear correlation between the brightness of the source and its amplitude of variability (rms-flux relation) and obeys the same quantitative scaling relation as stellar-mass black holes and active galactic nuclei. We also show that the most important parameter in this scaling relation is the physical size of the accreting object. This establishes the universality of accretion physics from proto-stars still in the star-forming process to the supermassive black holes at the centers of galaxies. PMID:26601307

  2. Combination of sodium caseinate and succinylated alginate improved stability of high fat fish oil-in-water emulsions.

    PubMed

    Yesiltas, Betül; Sørensen, Ann-Dorit Moltke; García-Moreno, Pedro J; Anankanbil, Sampson; Guo, Zheng; Jacobsen, Charlotte

    2018-07-30

    Sodium caseinate (CAS) and commercial sodium alginate (CA), long chain modified alginate (LCMA) or short chain modified alginate (SCMA) were used in combination for emulsifying and stabilizing high fat (50-70%) fish oil-in-water emulsions. Physical (creaming, droplet size, viscosity and protein determination) and oxidative (primary and secondary oxidation products) stabilities of the emulsions were studied during 12 days of storage. Creaming stability was higher for emulsions produced with alginates and CAS compared to emulsions prepared with only CAS. Combined use of CAS + LCMA performed better in terms of physical stability compared to emulsions produced with only CAS. However, the oxidative stability of this emulsion was inferior probably due to the presence of an unsaturated carbon chain in LCMA structure. CAS + SCMA emulsions not only showed better physical stability such as smaller droplet size, lower creaming and higher viscosity, but also had an improved oxidative stability than emulsions produced with only CAS. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. [Analysis of workplace health promotion and its effect on work ability and health-related quality of life in a medium-sized business].

    PubMed

    Biallas, B; Froböse, I; Zöller, M; Wilke, C

    2015-05-01

    This study analyses the effect of workplace health promotion on work ability and health-related quality of life in white-collar and blue-collar workers in a medium-sized business. The intervention group contains 75 subjects with a mean age of 36.6±10.63 years (55 men, 20 women). The participation rate is 47%. White-collar workers show improvement in their health-related quality of life regarding physical and psychological aspects and work ability. Physically inactive employees show improvement in their health-related quality of life regarding physical and psychological aspects as well as context. Active employees only show significant improvement in terms of work ability. In conclusion, the promotion of exercise in the context of occupational health promotion has a positive effect on quality of life and work ability of employees and, thus, is a benefit for both the individual as well as the business itself. © Georg Thieme Verlag KG Stuttgart · New York.

  4. Can physical activity improve peak bone mass?

    PubMed

    Specker, Bonny; Minett, Maggie

    2013-09-01

    The pediatric origin of osteoporosis has led many investigators to focus on determining factors that influence bone gain during growth and methods for optimizing this gain. Bone responds to bone loading activities by increasing mass or size. Overall, pediatric studies have found a positive effect of bone loading on bone size and accrual, but the types of loads necessary for a bone response have only recently been investigated in human studies. Findings indicate that responses vary by sex, maturational status, and are site-specific. Estrogen status, body composition, and nutritional status also may influence the bone response to loading. Despite the complex interrelationships among these various factors, it is prudent to conclude that increased physical activity throughout life is likely to optimize bone health.

  5. A New Type of Atom Interferometry for Testing Fundamental Physics

    NASA Astrophysics Data System (ADS)

    Lorek, Dennis; Lämmerzahl, Claus; Wicht, Andreas

    We present a new type of atom interferometer (AI) that provides a tool for ultra-high precision tests of fundamental physics. As an example we present how an AI based on highly charged hydrogen-like atoms is affected by gravitational waves (GW). A qualitative description of the quantum interferometric measurement principle is given, the modifications in the atomic Hamiltonian caused by the GW are presented, and the size of the resulting frequency shifts in hydrogen-like atoms is estimated. For a GW amplitude of h = 10-23 the frequency shift is of the order of 110μHz for an AI based on a 91-fold charged uranium ion. A frequency difference of this size can be resolved by current AIs in 1s.

  6. Are K-12 learners motivated in physical education? A meta-analysis.

    PubMed

    Chen, Senlin; Chen, Ang; Zhu, Xihe

    2012-03-01

    Previous studies devoted to K-12 learner motivation in physical education share a general assumption that students may lack motivation. This meta-analytic study examined published original studies (n = 79) to determine students' motivation level and the association between motivation and outcomes. Original means of motivation measures were converted and aggregated to determine motivation levels. Correlation effect sizes were calculated to determine the association between motivation and outcome measures. The analyses revealed that K-12 students are motivated regardless of the theoretical constructs used in the studies (M > 50). The correlation effect sizes (r = .20-.30, p < .05) indicate a weak association between motivation and outcome. The findings suggest a need to involve meaningful learning and pedagogy variables in motivation research.

  7. Determination of Molecular Self-Diffusion Coefficients Using Pulsed-Field-Gradient NMR: An Experiment for Undergraduate Physical Chemistry Laboratory

    ERIC Educational Resources Information Center

    Harmon, Jennifer; Coffman, Cierra; Villarrial, Spring; Chabolla, Steven; Heisel, Kurt A.; Krishnan, Viswanathan V.

    2012-01-01

    NMR spectroscopy has become one of the primary tools that chemists utilize to characterize a range of chemical species in the solution phase, from small organic molecules to medium-sized proteins. A discussion of NMR spectroscopy is an essential component of physical and biophysical chemistry lecture courses, and a number of instructional…

  8. Creating a Safe School Environment: How to Prevent Cyberbullying at Your School

    ERIC Educational Resources Information Center

    Diamanduros, Terry; Downs, Elizabeth

    2011-01-01

    Technology has changed the school yard or neighborhood bully. It no longer requires physical intimidation to be a bully. In fact, bullying can be done anonymously, on or off campus, and physical size does not enter into the scenario. Every year headlines identify children who take their own lives as a result of being victims of various forms of…

  9. Finsler Geometry of Nonlinear Elastic Solids with Internal Structure

    DTIC Science & Technology

    2017-01-01

    should enable regularized numerical solutions with discretization -size independence for representation of materials demonstrating softening, e.g...additional possibility of a discrete larger void/cavity forming at the core of the sphere. In the second case, comparison with the classical...core of the domain. This hollow sphere physically represents a discrete cavity, while the constant field ξH physically represents a continuous

  10. "BE"ing a Certain Way: Seeking "Body Image" in Canadian Health and Physical Education Curriculum Policies

    ERIC Educational Resources Information Center

    Robertson, Lorayne; Thomson, Dianne

    2012-01-01

    Body image is an individual's emotional response to one's appearance including size and shape; this response may not be helpful in the pursuit of overall health and well-being. This policy analysis examines the treatment of body image in Canadian Health and Physical Education (HPE) curriculum policies using a body image analysis framework…

  11. Correlation analysis for the incubation period of prion disease

    PubMed Central

    Bae, Se-Eun; Jung, Sunghoon; Kim, Ha-Yeon; Son, Hyeon S.

    2012-01-01

    Previous studies have shown that genetic quantitative trait loci (QTL), strain barriers, inoculation dose and inoculation method modulate the incubation period of prion diseases. We examined the relationship between a diverse set of physical, genetic and immunological characteristics and the incubation period of prion disease using correlation analyses. We found that incubation period was highly correlated with brain weight. In addition, mean corpuscular volume and cell size were strongly correlated with incubation period, indicating that the physical magnitude of prion-infected organs or individual cells may be important in determining the incubation period. Given the same prion inoculation dose, animals with a lower brain weight, mean corpuscular volume or cell size may experience more virulent disease, as the effective concentration of abnormal prion, which might regulate the attachment rate of prions to aggregates, is increased with smaller capacity of brains and cells. This is partly consistent with previous theoretical modeling. The strong correlations between incubation period and physical properties of the brain and cells in this study suggest that the mechanism underlying prion disease pathology may be physical, indicating that the incubation process is governed by simple chemical stoichiometry. PMID:22561168

  12. Flow properties and chemical composition of carob (Ceratonia siliqua L.) flours as related to particle size and seed presence.

    PubMed

    Benković, Maja; Belščak-Cvitanović, Ana; Bauman, Ingrid; Komes, Draženka; Srečec, Siniša

    2017-10-01

    Due to abundance in carbohydrates, dietary fibres and bioactive compounds, as well as for its outspread and low prices, carob (Ceratonia siliqua L.) flour has a great potential of use as a functional ingredient. The aim of this study was to analyse this potential by physical and chemical properties assessment of different particle sizes of carob flour with and without seeds. The influence of seed presence on physical and chemical properties of flour was also investigated. Seed presence in carob flour led to higher cohesivity and cake strength. It also affected the extraction efficiency of polyphenols, which was confirmed by the ranking of samples according to their procyanidin and tannins contents. With regard to the carbohydrate content, significant differences (P<0.05) between the contents of fructose and glucose was established in samples differing by the presence of carob seeds. Spearman rank order correlations revealed a significant difference (P<0.05) between physical and chemical properties of carob flours. These findings confirm the importance of understanding physical and chemical properties of carob flours in order to use them efficiently as a functional food ingredient. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Cross-Sectional Study of Young Adults Diagnosed With Juvenile Fibromyalgia: Social Support and Its Impact on Functioning and Mood.

    PubMed

    Lynch-Jordan, Anne M; Sil, Soumitri; Bromberg, Maggie; Ting, Tracy V; Kashikar-Zuck, Susmita

    2015-11-01

    Juvenile-onset fibromyalgia (JFM) affects physical, social, and emotional functioning. Little is known about how social support and social interactions are impacted in the transition to young adulthood for patients diagnosed with JFM. Young adults (Mage = 21.6) diagnosed with JFM during adolescence (N = 94) and matched healthy controls (N = 33) completed measures of social network size and diversity, perceived social support, physical functioning, and depressive symptoms as part of a cross-sectional survey study. No difference in social network diversity was found, although JFM patients reported fewer total people within their social networks. JFM patients reported poorer emotional and tangible support and fewer positive social interactions than healthy controls. After controlling for condition and pain intensity, the level of perceived social support was a significant predictor of physical functioning and depressive symptoms, whereas social network size also contributed uniquely to physical functioning. Given the developmental importance of social support in adolescence and young adulthood, interventions should include methods of improving social support into fibromyalgia management. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  14. A theoretical approach to study the melting temperature of metallic nanowires

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arora, Neha; Joshi, Deepika P.

    2016-05-23

    The physical properties of any material change with the change of its size from bulk range to nano range. A theoretical study to account for the size and shape effect on melting temperature of metallic nanowires has been done. We have studied zinc (Zn), indium (In), lead (Pb) and tin (Sn) nanowires with three different cross sectional shapes like regular triangular, square and regular hexagonal. Variation of melting temperature with the size and shape is graphically represented with the available experimental data. It was found that melting temperature of the nanowires decreases with decrement in the size of nanowire, duemore » to surface effect and at very small size the most probable shape also varies with material.« less

  15. A solid-state NMR method to determine domain sizes in multi-component polymer formulations

    NASA Astrophysics Data System (ADS)

    Schlagnitweit, Judith; Tang, Mingxue; Baias, Maria; Richardson, Sara; Schantz, Staffan; Emsley, Lyndon

    2015-12-01

    Polymer domain sizes are related to many of the physical properties of polymers. Here we present a solid-state NMR experiment that is capable of measuring domain sizes in multi-component mixtures. The method combines selective excitation of carbon magnetization to isolate a specific component with proton spin diffusion to report on domain size. We demonstrate the method in the context of controlled release formulations, which represents one of today's challenges in pharmaceutical science. We show that we can measure domain sizes of interest in the different components of industrial pharmaceutical formulations at natural isotopic abundance containing various (modified) cellulose derivatives, such as microcrystalline cellulose matrixes that are film-coated with a mixture of ethyl cellulose (EC) and hydroxypropyl cellulose (HPC).

  16. Hard-sphere fluid adsorbed in an annular wedge: The depletion force of hard-body colloidal physics

    NASA Astrophysics Data System (ADS)

    Herring, A. R.; Henderson, J. R.

    2007-01-01

    Many important issues of colloidal physics can be expressed in the context of inhomogeneous fluid phenomena. When two large colloids approach one another in solvent, they interact at least partly by the response of the solvent to finding itself adsorbed in the annular wedge formed between the two colloids. At shortest range, this fluid mediated interaction is known as the depletion force/interaction because solvent is squeezed out of the wedge when the colloids approach closer than the diameter of a solvent molecule. An equivalent situation arises when a single colloid approaches a substrate/wall. Accurate treatment of this interaction is essential for any theory developed to model the phase diagrams of homogeneous and inhomogeneous colloidal systems. The aim of our paper is a test of whether or not we possess sufficient knowledge of statistical mechanics that can be trusted when applied to systems of large size asymmetry and the depletion force in particular. When the colloid particles are much larger than a solvent diameter, the depletion force is dominated by the effective two-body interaction experienced by a pair of solvated colloids. This low concentration limit of the depletion force has therefore received considerable attention. One route, which can be rigorously based on statistical mechanical sum rules, leads to an analytic result for the depletion force when evaluated by a key theoretical tool of colloidal science known as the Derjaguin approximation. A rival approach has been based on the assumption that modern density functional theories (DFT) can be trusted for systems of large size asymmetry. Unfortunately, these two theoretical predictions differ qualitatively for hard sphere models, as soon as the solvent density is higher than about 2/3 that at freezing. Recent theoretical attempts to understand this dramatic disagreement have led to the proposal that the Derjaguin and DFT routes represent opposite limiting behavior, for very large size asymmetry and molecular sized mixtures, respectively. This proposal implies that nanocolloidal systems lie in between the two limits, so that the depletion force no longer scales linearly with the colloid radius. That is, by decreasing the size ratio from mesoscopic to molecular sized solutes, one moves smoothly between the Derjaguin and the DFT predictions for the depletion force scaled by the colloid radius. We describe the results of a simulation study designed specifically as a test of compatibility with this complex scenario. Grand canonical simulation procedures applied to hard-sphere fluid adsorbed in a series of annular wedges, representing the depletion regime of hard-body colloidal physics, confirm that neither the Derjaguin approximation, nor advanced formulations of DFT, apply at moderate to high solvent density when the geometry is appropriate to nanosized colloids. Our simulations also allow us to report structural characteristics of hard-body solvent adsorbed in hard annular wedges. Both these aspects are key ingredients in the proposal that unifies the disparate predictions, via the introduction of new physics. Our data are consistent with this proposed physics, although as yet limited to a single colloidal size asymmetry.

  17. The Dynamic Family Home: a qualitative exploration of physical environmental influences on children's sedentary behaviour and physical activity within the home space.

    PubMed

    Maitland, Clover; Stratton, Gareth; Foster, Sarah; Braham, Rebecca; Rosenberg, Michael

    2014-12-24

    Recent changes in home physical environments, such as decreasing outdoor space and increasing electronic media, may negatively affect health by facilitating sedentariness and reducing physical activity. As children spend much of their time at home they are particularly vulnerable. This study qualitatively explored family perceptions of physical environmental influences on sedentary behaviour and physical activity within the home space. Home based interviews were conducted with 28 families with children aged 9-13 years (total n = 74 individuals), living in Perth, Australia. Families were stratified by socioeconomic status and selected to provide variation in housing. Qualitative methods included a family interview, observation and home tour where families guided the researcher through their home, enabling discussion while in the physical home space. Audio recordings were transcribed verbatim and thematically analysed. Emergent themes related to children's sedentariness and physical activity included overall size, space and design of the home; allocation of home space; equipment within the home space; perceived safety of the home space; and the changing nature of the home space. Families reported that children's activity options were limited when houses and yards were small. In larger homes, multiple indoor living rooms usually housed additional sedentary entertainment options, although parents reported that open plan home layouts could facilitate monitoring of children's electronic media use. Most families reported changing the allocation and contents of their home space in response to changing priorities and circumstances. The physical home environment can enhance or limit opportunities for children's sedentary behaviour and physical activity. However, the home space is a dynamic ecological setting that is amenable to change and is largely shaped by the family living within it, thus differentiating it from other settings. While size and space were considered important, how families prioritise the use of their home space and overcome the challenges posed by the physical environment may be of equal or greater importance in establishing supportive home environments. Further research is required to tease out how physical, social and individual factors interact within the family home space to influence children's sedentary behaviour and physical activity at home.

  18. Microbubble Sizing and Shell Characterization Using Flow Cytometry

    PubMed Central

    Tu, Juan; Swalwell, Jarred E.; Giraud, David; Cui, Weicheng; Chen, Weizhong; Matula, Thomas J.

    2015-01-01

    Experiments were performed to size, count, and obtain shell parameters for individual ultrasound contrast microbubbles using a modified flow cytometer. Light scattering was modeled using Mie theory, and applied to calibration beads to calibrate the system. The size distribution and population were measured directly from the flow cytometer. The shell parameters (shear modulus and shear viscosity) were quantified at different acoustic pressures (from 95 to 333 kPa) by fitting microbubble response data to a bubble dynamics model. The size distribution of the contrast agent microbubbles is consistent with manufacturer specifications. The shell shear viscosity increases with increasing equilibrium microbubble size, and decreases with increasing shear rate. The observed trends are independent of driving pressure amplitude. The shell elasticity does not vary with microbubble size. The results suggest that a modified flow cytometer can be an effective tool to characterize the physical properties of microbubbles, including size distribution, population, and shell parameters. PMID:21622051

  19. Correlates of self worth and body size dissatisfaction among obese Latino youth

    PubMed Central

    Mirza, Nazrat M; Mackey, Eleanor Race; Armstrong, Bridget; Jaramillo, Ana; Palmer, Matilde M

    2011-01-01

    The current study examined self-worth and body size dissatisfaction, and their association with maternal acculturation among obese Latino youth enrolled in a community-based obesity intervention program. Upon entry to the program, a sample of 113 participants reported global self-worth comparable to general population norms, but lower athletic competence and perception of physical appearance. Interestingly, body size dissatisfaction was more prevalent among younger respondents. Youth body size dissatisfaction was associated with less acculturated mothers and higher maternal dissatisfaction with their child's body size. By contrast, although global self-worth was significantly related to body dissatisfaction, it was not influenced by mothers’ acculturation or dissatisfaction with their own or their child’s body size. Obesity intervention programs targeted to Latino youth need to address self-worth concerns among the youth as well as addressing maternal dissatisfaction with their children’s body size. PMID:21354881

  20. Size matters in the water uptake and hygroscopic growth of atmospherically relevant multicomponent aerosol particles.

    PubMed

    Laskina, Olga; Morris, Holly S; Grandquist, Joshua R; Qin, Zhen; Stone, Elizabeth A; Tivanski, Alexei V; Grassian, Vicki H

    2015-05-14

    Understanding the interactions of water with atmospheric aerosols is crucial for determining the size, physical state, reactivity, and climate impacts of this important component of the Earth's atmosphere. Here we show that water uptake and hygroscopic growth of multicomponent, atmospherically relevant particles can be size dependent when comparing 100 nm versus ca. 6 μm sized particles. It was determined that particles composed of ammonium sulfate with succinic acid and of a mixture of chlorides typical of the marine environment show size-dependent hygroscopic behavior. Microscopic analysis of the distribution of components within the aerosol particles show that the size dependence is due to differences in the mixing state, that is, whether particles are homogeneously mixed or phase separated, for different sized particles. This morphology-dependent hygroscopicity has consequences for heterogeneous atmospheric chemistry as well as aerosol interactions with electromagnetic radiation and clouds.

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