31 CFR 539.504 - Departments and agencies of the United States Government.

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

31 CFR 539.504 - Departments and agencies of the United States Government.

Code of Federal Regulations, 2011 CFR

2011-07-01

... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

31 CFR 539.504 - Departments and agencies of the United States Government.

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

31 CFR 539.504 - Departments and agencies of the United States Government.

Code of Federal Regulations, 2013 CFR

2013-07-01

... requirements under defense production agreements; intelligence requirements; sole source suppliers, spare parts... Office of Chemical, Biological and Missile Nonproliferation and the Office of the Assistant Legal Adviser...

Promoting Intercultural Competency in the Nuclear Workplace

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bachner K. M.

Intercultural preparedness training is a staple of many workplaces that require international competence, including government, business, and non-profits. Even highly experienced diplomats are often advised to attend training sessions on this topic. Intercultural preparedness training promises to be especially relevant and useful for professionals working in the field of nuclear nonproliferation, including in the application of international nuclear safeguards. This paper outlines the fundamental philosophies underlying a training program that will benefit professionals in the nuclear arena, whether practitioners of nonproliferation or other sub-fields relying on international cooperation and collaboration, and how such a training program might be implemented efficiently.

75 FR 1020 - Amendments to the Export Administration Regulations (EAR) Based Upon the Accession of Albania and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-08

...--Commerce Country Chart [Reason for control] Countries Chemical & biological Nuclear National Security Missile Regional Stability Firearms Crime control Anti-terrorism weapons nonproliferation Tech convention...

Consistent morals

NASA Astrophysics Data System (ADS)

Cohen, Howard; Amini, Ehsan; Herrera, Julio

2014-04-01

In reply to a physicsworld.com blog post about a talk by Amy Smithson, a non-proliferation expert, in which she criticized scientists who work on nuclear, chemical or biological weapons (“A question of responsibility”, 16 February, http://ow.ly/ulIWu).

76 FR 36986 - Export Controls for High Performance Computers: Wassenaar Arrangement Agreement Implementation...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

... regimes and is working on becoming a member of the regimes. Albania and Croatia are parties to the Nuclear Non-Proliferation Treaty, the Chemical Weapons Convention, and the Biological Weapons Convention. In...

15 CFR Supplement No. 1 to Part 742 - Nonproliferation of Chemical and Biological Weapons

Code of Federal Regulations, 2012 CFR

2012-01-01

...-by-case basis or other applicable licensing policies that were in effect prior to the contract..., triethanolamine, diisopropylamine, sodium sulfide, and N,N-diethylethanolamine is December 12, 1989. (6) The...

15 CFR Supplement No. 1 to Part 742 - Nonproliferation of Chemical and Biological Weapons

Code of Federal Regulations, 2013 CFR

2013-01-01

...-by-case basis or other applicable licensing policies that were in effect prior to the contract..., triethanolamine, diisopropylamine, sodium sulfide, and N,N-diethylethanolamine is December 12, 1989. (6) The...

15 CFR Supplement No. 1 to Part 742 - Nonproliferation of Chemical and Biological Weapons

Code of Federal Regulations, 2014 CFR

2014-01-01

...-by-case basis or other applicable licensing policies that were in effect prior to the contract..., triethanolamine, diisopropylamine, sodium sulfide, and N,N-diethylethanolamine is December 12, 1989. (6) The...

15 CFR 752.5 - Steps you must follow to apply for an SCL.

Code of Federal Regulations, 2011 CFR

2011-01-01

... items controlled for nuclear nonproliferation or chemical and biological control reasons. (3) ICP. You.... The items exported will be retained under my (our) ownership and control, and will be returned by me...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooper, R.

Since the end of the Cold War the world has witnessed a remarkable series of events demonstrating that universal adherence to the principles of nuclear non-proliferation and disarmament are no longer utopian dreams. The author reviews the actions of various countries to terminate or reduce nuclear weapons programs and those that are resisting the non-proliferation efforts. The author addresses efforts of the International Atomic Energy Agency (IAEA) to safeguard declared nuclear material more cost-effectively and deal with the possibility of undeclared nuclear activities.

Proliferation Control Regimes: Background and Status

DTIC Science & Technology

2012-10-25

States has signed such agreements with Antigua and Barbuda, the Bahamas, Belize, Croatia, Cyprus, Liberia, Malta, the Marshall Islands , Mongolia...Chemical Weapons Convention (CWC), the Biological and Toxin Weapons Convention (BWC), and the Australia Group. The informal Australia Group...biological agents or toxins “of types and in quantities that have no justification for peaceful purposes.” The missile nonproliferation regime is founded not

Biosafety and biosecurity as essential pillars of international health security and cross-cutting elements of biological nonproliferation

PubMed Central

2010-01-01

The critical aspects of biosafety, biosecurity, and biocontainment have been in the spotlight in recent years. There have also been increased international efforts to improve awareness of modern practices and concerns with regard to the safe pursuit of life sciences research, and to optimize current oversight frameworks, thereby resulting in decreased risk of terrorist/malevolent acquisition of deadly pathogens or accidental release of a biological agent, and increased safety of laboratory workers. Our purpose is to highlight how the World Health Organization’s (WHO) revised International Health Regulations (IHR[2005]), the Biological Weapons Convention (BWC), and the United Nations Security Council Resolution (UNSCR) 1540 overlap in their requirements with regard to biosafety and biosecurity in order to improve the understanding of practitioners and policymakers and maximize the use of national resources employed to comply with internationally-mandated requirements. The broad range of goals of these international instruments, which are linked by the common thread of biosafety and biosecurity, highlight their significance as essential pillars of international health security and cross-cutting elements of biological nonproliferation. The current efforts of the Republic of Georgia to enhance biosafety and biosecurity in accordance with these international instruments are summarized. PMID:21143822

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quirk, W.J.; Canada, J.; de Vore, L.

This monthly report of research activities at Lawrence Livermore Laboratory highlights three different research programs. First, the Forensic Science Center supports a broad range of analytical techniques that focus on detecting and analyzing chemical, biological, and nuclear species. Analyses are useful in the areas of nonproliferation, counterterrorism, and law enforcement. Second, starting in 1977, the laboratory initiated a series of studies to understand a high incidence of melanoma among employees. Continued study shows that mortality from this disease has decreased from the levels seen in the 1980`s. Third, to help coordinate the laboratory`s diverse research projects that can provide bettermore » healthcare tools to the public, the lab is creating the new Center for Healthcare Technologies.« less

Fiscal Year 2014 Annual Report on BNLs Next Generation Safeguards Initiative Human Capital Development Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pepper, Susan E.

2014-10-10

Brookhaven National Laboratory’s (BNL’s) Nonproliferation and National Security Department contributes to the National Nuclear Security Administration Office of Nonproliferation and International Security Next Generation Safeguards Initiative (NGSI) through university engagement, safeguards internships, safeguards courses, professional development, recruitment, and other activities aimed at ensuring the next generation of international safeguards professionals is adequately prepared to support the U.S. safeguards mission. This report is a summary of BNL s work under the NGSI program in Fiscal Year 2014.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pelland, B.

Four years ago, Saddam Hussein invaded Kuwait with the intention of annexing it as Iraq's 19th state. The disclosure of the Iraqi nuclear weapons program in the aftermath of the Gulf War--through the IAEA inspections--signaled the end of one proliferation era and the start of the next. In the author's remarks here, he has found it useful to identify four distinct proliferation eras, each with different features, each calling for different emphasis in international nonproliferation efforts. They provide a convenient way to look at the history of nonproliferation, and to look into the future and to the new dimensions inmore » nonproliferation that are slowly emerging. Since the Gulf War, the nuclear world experienced a series of events of fundamental significance that changed the nature of nonproliferation, forcing changes in the mission of the IAEA and its methods. Certainly some of these events came in the form of unpleasant surprises, such as in Iraq, but very positive progress was also made on other fronts. He would like to share some perceptions of the events creating the present situation, and some views anticipating the requirements most likely to emerge in the coming years.« less

Arms Control and Nonproliferation: A Catalog of Treaties and Agreements

DTIC Science & Technology

2012-03-07

and Barbuda, the Bahamas, Belize, Croatia, Cyprus, Liberia, Malta, the Marshall Islands , Mongolia, Panama, and Saint Vincent and the Grenadines... toxin weapons, mandates the destruction of all chemical weapons production facilities, and seeks to control the production and international transfer...and transfer of biological weapons, as well as biological agents and toxins . It also bans “equipment or means of delivery designed to use such

Strengthening Biosecurity in Iraq: Development of a National Biorisk Management System

PubMed Central

Al Jewari, Mahdi F. H.; Koblentz, Gregory D.

2016-01-01

Since 2004, the Republic of Iraq has undertaken a concerted effort to comply with all of its international obligations to prevent the proliferation and the use of chemical, biological, radiological, and nuclear (CBRN) weapons. A centerpiece of this effort is Iraq’s development of a National Biorisk Management System. The Iraqi National Monitoring Authority (INMA), which is responsible for CBRN security and non-proliferation in Iraq, has played a key role in establishing this system. This article provides an overview of Iraq’s international non-proliferation commitments, describes the legal and organizational steps it has taken to implement these commitments, and examines current initiatives to strengthen Iraq’s biosecurity. PMID:26952002

A comparison of the additional protocols of the five nuclear weapon states and the ensuing safeguards benefits to international nonproliferation efforts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uribe, Eva C; Sandoval, M Analisa; Sandoval, Marisa N

2009-01-01

With the 6 January 2009 entry into force of the Additional Protocol by the United States of America, all five declared Nuclear Weapon States that are part of the Nonproliferation Treaty have signed, ratified, and put into force the Additional Protocol. This paper makes a comparison of the strengths and weaknesses of the five Additional Protocols in force by the five Nuclear Weapon States with respect to the benefits to international nonproliferation aims. This paper also documents the added safeguards burden to the five declared Nuclear Weapon States that these Additional Protocols put on the states with respect to accessmore » to their civilian nuclear programs and the hosting of complementary access activities as part of the Additional Protocol.« less

Strengthening the nuclear nonproliferation regime : focus on the civilian nuclear fuel cycle.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saltiel, David H.; Pregenzer, Arian Leigh

2005-04-01

Leaders around the world and across the ideological spectrum agree that the global nonproliferation regime is facing a serious test. The emergence of sophisticated terrorist networks, black markets in nuclear technology, and technological leaps associated with globalization have conspired to threaten one of the most successful examples of international cooperation in history. The rampant proliferation of nuclear weapons that was predicted at the start of the nuclear age has been largely held in check and the use of those weapons avoided. Nonetheless, with the thirty-fifth anniversary of the Treaty on the Nonproliferation of Nuclear Weapons (NPT), the threat of nuclearmore » proliferation seems more serious than ever. Although experts readily concede that there exist many pathways to proliferation, the threat posed by the misuse of the civilian nuclear fuel cycle has received considerable recent attention. While the connection between nuclear energy and nonproliferation has been a topic of discussion since the dawn of the nuclear age, world events have brought the issue to the forefront once again. United States President George W. Bush and International Atomic Energy Agency (IAEA) Director General Mohammad ElBaradei are among those who have highlighted proliferation risks associated with civilian nuclear power programs and called for revitalizing the nuclear nonproliferation regime to address new threats. From the possibility of diversion or theft of nuclear material or technology, to the use of national civilian programs as a cover for weapons programs - what some have called latent proliferation - the fuel cycle appears to many to represent a glaring proliferation vulnerability. Just as recognition of these risks is not new, neither is recognition of the many positive benefits of nuclear energy. In fact, a renewed interest in exploiting these benefits has increased the urgency of addressing the risks. Global energy demand is expected to at least double by the middle of the century and could increase even more quickly. Much of the new demand will come from the rapidly expanding economies in China and India, but much of the developing world stands poised to follow the same path. This growth in demand is paralleled by concerns about global warming and the long-term reliability of carbon-based fuel supplies, concerns which expanded use of nuclear power can help to address. For these reasons and others, many countries in Asia have already clearly signaled that nuclear energy will play a key role for years to come. Numerous proposals have been made in the last two years for reducing the proliferation risk of the civilian nuclear fuel cycle. These range from a ban on export of enrichment and reprocessing technology to countries not already possessing operational capabilities to multinational management of the nuclear fuel cycle and strengthening existing monitoring and security mechanisms. The need for international willingness to enforce nonproliferation commitments and norms has also been emphasized. Some of these proposals could significantly impact the production of nuclear energy. Because the successful strengthening of the nonproliferation regime and the expansion of nuclear energy are so closely related, any successful approach to resolving these issues will require the creative input of experts from both the nuclear energy and nonproliferation communities. Against this backdrop, Sandia National Laboratories organized its 14th International Security Conference (ISC) around the theme: Strengthening the Nuclear Nonproliferation Regime: Focus on the Civilian Nuclear Fuel Cycle. The goal of the conference was to begin a constructive dialogue between the nuclear energy and nuclear nonproliferation communities. The conference was held in Chantilly, Virginia, just outside Washington, D.C. on April 4-6, 2005, and was attended by approximately 125 participants from fifteen countries. The ISC agenda was structured to produce a systematic review of the connection between civilian nuclear energy programs and the proliferation of nuclear weapons and to identify constructive approaches to strengthen the nonproliferation regime. The conference began by reviewing the energy and security context that has, once again, raised the profile of this issue. A discussion of the risks associated with the civilian nuclear fuel cycle was then used to inform the analysis of several potential risk-management tools. The conference concluded by looking for lessons from the past as well as looking forward to future opportunities, with a particular focus on East Asia. In this paper we summarize the debates and ideas that emerged during the conference. Although we have drawn on material presented by speakers and comments made by participants, we do not quote or cite the specific contributions of individuals.« less

Combating the Proliferation of Weapons of Mass Destruction.

ERIC Educational Resources Information Center

Jenkins, Bonnie

1997-01-01

Reveals the growing threat posed to all countries by the proliferation of weapons of mass destruction. Discusses the international effort combating this proliferation including the Nuclear Non-Proliferation Treaty, Strategic Arms Reduction Treaties, Biological Weapons Convention, and Chemical Weapons Convention. Also considers regional arms…

15 CFR Supplement No. 1 to Part 742 - Nonproliferation of Chemical and Biological Weapons

Code of Federal Regulations, 2010 CFR

2010-01-01

... Iran of dimethyl methylphosphonate, phosphorus oxychloride, and thiodiglycol is February 22, 1989. (5... hydrogen fluoride, sodium fluoride, sodium bifluoride, phosphorus pentasulfide, sodium cyanide... contract sanctity date for exports to all destinations (except Iran or Syria) of phosphorus trichloride...

15 CFR Supplement No. 1 to Part 742 - Nonproliferation of Chemical and Biological Weapons

Code of Federal Regulations, 2011 CFR

2011-01-01

... Iran of dimethyl methylphosphonate, phosphorus oxychloride, and thiodiglycol is February 22, 1989. (5... hydrogen fluoride, sodium fluoride, sodium bifluoride, phosphorus pentasulfide, sodium cyanide... contract sanctity date for exports to all destinations (except Iran or Syria) of phosphorus trichloride...

15 CFR 740.12 - Gift parcels and humanitarian donations (GFT).

Code of Federal Regulations, 2011 CFR

2011-01-01

..., and nuclear nonproliferation, missile technology or crime control reasons (see supplement No. 1 to... destinations, no items controlled for chemical and biological weapons (CB), missile technology (MT), national security (NS), nuclear proliferation (NP) or encryption items (EI) reasons on the Commerce Control List...

15 CFR 740.12 - Gift parcels and humanitarian donations (GFT).

Code of Federal Regulations, 2010 CFR

2010-01-01

..., and nuclear nonproliferation, missile technology or crime control reasons (see Supplement No. 1 to... destinations, no items controlled for chemical and biological weapons (CB), missile technology (MT), national security (NS), nuclear proliferation (NP) or encryption items (EI) reasons on the Commerce Control List...

Russian University Education in Nuclear Safeguards and Security

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duncan, Cristen L.; Kryuchkov, Eduard F.; Geraskin, Nikolay I.

2009-03-15

As safeguards and security (S&S) systems are installed and upgraded in nuclear facilities throughout Russia, it becomes increasingly important to develop mechanisms for educating future Russian nuclear scientists and engineers in the technologies and methodologies of physical protection (PP) and nuclear material control and accounting (MC&A). As part of the U.S. Department of Energy’s (DOE) program to secure nuclear materials in Russia, the Education Project supports technical S&S degree programs at key Russian universities and nonproliferation education initiatives throughout the Russian Federation that are necessary to achieve the overall objective of fostering qualified and vigilant Russian S&S personnel. The Educationmore » Project supports major educational degree programs at the Moscow Engineering Physics Institute (MEPhI) and Tomsk Polytechnic University (TPU). The S&S Graduate Program is available only at MEPhI and is the world’s first S&S degree program. Ten classes of students have graduated with a total of 79 Masters Degrees as of early 2009. At least 84% of the graduates over the ten years are still working in the S&S field. Most work at government agencies or research organizations, and some are pursuing their PhD. A 5½ year Engineering Degree Program (EDP) in S&S is currently under development at MEPhI and TPU. The EDP is more tailored to the needs of nuclear facilities. The program’s first students (14) graduated from MEPhI in February 2007. Similar-sized classes are graduating from MEPhI each February. All of the EDP graduates are working in the S&S field, many at nuclear facilities. TPU also established an EDP and graduated its first class of approximately 18 students in February 2009. For each of these degree programs, the American project team works with MEPhI and TPU to develop appropriate curriculum, identify and acquire various training aids, develop and publish textbooks, and strengthen instructor skills. The project has also supported the instruction of policy-oriented nonproliferation courses at various Russian universities. These courses are targeted towards future workers in the nuclear field to help build an effective nonproliferation awareness within the nuclear complex. A long-range goal of this project is to assist the educational programs at MEPhI and TPU in becoming self-sustainable and therefore able to maintain the three degree programs without DOE support. This paper describes current development of these education programs and new initiatives. The paper also describes general nonproliferation education activities supported by DOE that complement the more technical S&S degree programs.« less

Taking a stand against nuclear proliferation: the pediatrician's role.

PubMed

Newman, Thomas B

2008-05-01

Nuclear weapons pose a grave threat to the health of children. The Nuclear Nonproliferation Treaty, which for almost 40 years has limited the spread of nuclear weapons, is in danger of unraveling. At the 2000 Nuclear Nonproliferation Treaty Review Conference, 180 countries, including the United States, agreed on 13 practical steps to implement Article VI of the treaty, which calls for nuclear disarmament. However, the United States has acted in contravention of several of those disarmament steps, with announced plans to develop new nuclear weapons and to maintain a large nuclear arsenal for decades to come. Pediatricians, working individually and through organizations such as the American Academy of Pediatrics and International Physicians for the Prevention of Nuclear War, can educate the public and elected officials regarding the devastating and irremediable effects of nuclear weapons on children and the need for policies that comply with and strengthen the Nuclear Nonproliferation Treaty, rather than undermining it. For the children of the world, our goal must be a nuclear weapons convention (similar to the chemical and biological weapons conventions) that would prohibit these weapons globally.

15 CFR 738.2 - Commerce Control List (CCL) structure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1: Missile Technology reasons 2: Nuclear Nonproliferation reasons 3: Chemical & Biological Weapons...) Categories. The CCL is divided into 10 categories, numbered as follows: 0—Nuclear Materials, Facilities and... and Production Equipment C—Materials D—Software E—Technology (c) Order of review. In order to classify...

15 CFR 738.2 - Commerce Control List (CCL) structure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 1: Missile Technology reasons 2: Nuclear Nonproliferation reasons 3: Chemical & Biological Weapons...) Categories. The CCL is divided into 10 categories, numbered as follows: 0—Nuclear Materials, Facilities and... and Production Equipment C—Materials D—Software E—Technology (c) Order of review. In order to classify...

Systems resilience : a new analytical framework for nuclear nonproliferation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pregenzer, Arian Leigh

2011-12-01

This paper introduces the concept of systems resilience as a new framework for thinking about the future of nonproliferation. Resilience refers to the ability of a system to maintain its vital functions in the face of continuous and unpredictable change. The nonproliferation regime can be viewed as a complex system, and key themes from the literature on systems resilience can be applied to the nonproliferation system. Most existing nonproliferation strategies are aimed at stability rather than resilience, and the current nonproliferation system may be over-constrained by the cumulative evolution of strategies, increasing its vulnerability to collapse. The resilience of themore » nonproliferation system can be enhanced by diversifying nonproliferation strategies to include general international capabilities to respond to proliferation and focusing more attention on reducing the motivation to acquire nuclear weapons in the first place. Ideas for future research, include understanding unintended consequences and feedbacks among nonproliferation strategies, developing methodologies for measuring the resilience of the nonproliferation system, and accounting for interactions of the nonproliferation system with other systems on larger and smaller scales.« less

Nuclear Nonproliferation Ontology Assessment Team Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strasburg, Jana D.; Hohimer, Ryan E.

Final Report for the NA22 Simulations, Algorithm and Modeling (SAM) Ontology Assessment Team's efforts from FY09-FY11. The Ontology Assessment Team began in May 2009 and concluded in September 2011. During this two-year time frame, the Ontology Assessment team had two objectives: (1) Assessing the utility of knowledge representation and semantic technologies for addressing nuclear nonproliferation challenges; and (2) Developing ontological support tools that would provide a framework for integrating across the Simulation, Algorithm and Modeling (SAM) program. The SAM Program was going through a large assessment and strategic planning effort during this time and as a result, the relative importancemore » of these two objectives changed, altering the focus of the Ontology Assessment Team. In the end, the team conducted an assessment of the state of art, created an annotated bibliography, and developed a series of ontological support tools, demonstrations and presentations. A total of more than 35 individuals from 12 different research institutions participated in the Ontology Assessment Team. These included subject matter experts in several nuclear nonproliferation-related domains as well as experts in semantic technologies. Despite the diverse backgrounds and perspectives, the Ontology Assessment team functioned very well together and aspects could serve as a model for future inter-laboratory collaborations and working groups. While the team encountered several challenges and learned many lessons along the way, the Ontology Assessment effort was ultimately a success that led to several multi-lab research projects and opened up a new area of scientific exploration within the Office of Nuclear Nonproliferation and Verification.« less

78 FR 38782 - Lifting of Chemical and Biological Weapons (CBW) Proliferation Sanctions Against Chinese Entities

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-27

... Arms Control and International Security determined and certified to Congress that lifting sanctions on the following Chinese entities, their sub-units and successors is important to the national security... Security and Nonproliferation, Department of State, Telephone (202) 647-4930. SUPPLEMENTARY INFORMATION...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laughlin, Gary L.

The International, Homeland, and Nuclear Security (IHNS) Program Management Unit (PMU) oversees a broad portfolio of Sandia’s programs in areas ranging from global nuclear security to critical asset protection. We use science and technology, innovative research, and global engagement to counter threats, reduce dangers, and respond to disasters. The PMU draws on the skills of scientists and engineers from across Sandia. Our programs focus on protecting US government installations, safeguarding nuclear weapons and materials, facilitating nonproliferation activities, securing infrastructures, countering chemical and biological dangers, and reducing the risk of terrorist threats. We conduct research in risk and threat analysis, monitoringmore » and detection, decontamination and recovery, and situational awareness. We develop technologies for verifying arms control agreements, neutralizing dangerous materials, detecting intruders, and strengthening resiliency. Our programs use Sandia’s High-Performance Computing resources for predictive modeling and simulation of interdependent systems, for modeling dynamic threats and forecasting adaptive behavior, and for enabling decision support and processing large cyber data streams. In this report, we highlight four advanced computation projects that illustrate the breadth of the IHNS mission space.« less

6 CFR 5.2 - Public reading rooms.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the non-proliferation and verification research and development program; (v) The life sciences..., Washington, DC 20472 (for regional offices, consult your phone book); (20) For the Federal Computer Incident...

6 CFR 5.2 - Public reading rooms.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the non-proliferation and verification research and development program; (v) The life sciences..., Washington, DC 20472 (for regional offices, consult your phone book); (20) For the Federal Computer Incident...

6 CFR 5.2 - Public reading rooms.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the non-proliferation and verification research and development program; (v) The life sciences..., Washington, DC 20472 (for regional offices, consult your phone book); (20) For the Federal Computer Incident...

6 CFR 5.2 - Public reading rooms.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the non-proliferation and verification research and development program; (v) The life sciences..., Washington, DC 20472 (for regional offices, consult your phone book); (20) For the Federal Computer Incident...

6 CFR 5.2 - Public reading rooms.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the non-proliferation and verification research and development program; (v) The life sciences..., Washington, DC 20472 (for regional offices, consult your phone book); (20) For the Federal Computer Incident...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Graham, T.W.

There has been a growing debate over the future of US nonproliferation policy. Some, including this author, believe that many current trends, especially the increasing delegitimization of nuclear weapons for all forms of extended deterrence, provide an opportunity to think about winning the nonproliferation battle - freezing or reversing the nuclear programs of the four current de facto nuclear-weapon states (India, Israel, Pakistan, and South Africa), and ensuring that no additional states are added to this list for at least the next 20 years. Others, including some senior Pentagon officials, believe that additional proliferation is inevitable, and that a realisticmore » reading of international politics requires the US to focus much of its nonproliferation effort on managing the proliferation that does occur - attempting to reduce the risks to international security posed by those states that gain access to nuclear weapons. The outcome of this debate could have a major impact on the spread of nuclear weapons over the next two decades, and thereby on the dangers the world will face in the post-Cold War era.« less

The United States and the Future of the Nonproliferation Regime. Report of a Vantage Conference Cooperstown, New York, May 13-16, 1984).

ERIC Educational Resources Information Center

Stanley Foundation, Muscatine, IA.

The conference considered a broad range of issues regarding nuclear nonproliferation and U.S. policy objectives for the nonproliferation regime both in the near term and long term. Major areas receiving particular attention were developments affecting the context of the nonproliferation debate; the present status of the nonproliferation regime;…

Defining the Synthetic Biology Supply Chain

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frazar, Sarah L.; Hund, Gretchen E.; Bonheyo, George T.

In this article, a team of experts in synthetic biology, data analytics, and national security describe the overall supply chain surrounding synthetic biology. The team analyzes selected interactions within that network to better understand the risks raised by synthetic biology and identifies opportunities for risk mitigation. To introduce the concept, the article will briefly describe how an understanding of supply chains has been important in promoting nuclear nonproliferation objectives. The article concludes by assessing the structure and networks identified in the supply chains to reveal potential opportunities for future biodefense research and development; options for additional information exchange; and meansmore » to interdict, detect, or deter suspicious activity.« less

Evolution and resilience of the nuclear nonproliferation regime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pregenzer, Arian L.

2014-05-09

This paper introduces the concept of systems resilience as a new framework for thinking about the future of the nonproliferation regime. Resilience refers to the ability of a system to maintain its vital functions in the face of continuous and unpredictable change. First, I make the case that the nonproliferation regime can be viewed as a complex system. Next, I discuss key themes from the literature on systems resilience and apply them to the nonproliferation system: the difference between resilience and stability; the need for evolution to maintain function; the importance of functional diversity; and the concept of the adaptivemore » cycle. I show that most existing nonproliferation strategies are aimed at stability rather than resilience and that the current nonproliferation system may be over-constrained by the cumulative evolution of strategies. According to the literature on systems resilience, this increases its vulnerability to collapse. I argue that the resilience of the nonproliferation system can be enhanced by increasing international participation in setting the nonproliferation agenda, developing general international response capabilities, focusing on non-coercive approaches to decreasing demand, and applying systems thinking more rigorously to nonproliferation.« less

Beyond Boundaries: A Promising New Model for Security and Global Development. Carnegie Results

ERIC Educational Resources Information Center

Theroux, Karen

2013-01-01

In 2007, a team of international security experts and researchers at the Henry L. Stimson Center launched an initiative to build an effective model for sustainable nonproliferation of biological, chemical, and nuclear weapons. The project represented an exciting and innovative way of thinking about security: a dual-use approach that operated at…

Technical and Political Assessment of Peaceful Nuclear Power Program Prospects in North Africa and the Middle East

DOE Office of Scientific and Technical Information (OSTI.GOV)

Windsor, Lindsay K.; Kessler, Carol E.

An exceptional number of Middle Eastern and North African nations have recently expressed interest in developing nuclear energy for peaceful purposes. Many of these countries have explored nuclear research in limited ways in the past, but the current focused interest and application of resources towards developing nuclear-generated electricity and nuclear-powered desalination plants is unprecedented. Consequently, questions arise in response to this emerging trend: What instigated this interest? To what end(s) will a nuclear program be applied? Does the country have adequate technical, political, legislative, nonproliferation, and safety infrastructure required for the capability desired? If so, what are the next stepsmore » for a country in preparation for a future nuclear program? And if not, what collaboration efforts are possible with the United States or others? This report provides information on the capabilities and interests of 13 countries in the region in nuclear energy programs in light of safety, nonproliferation and security concerns. It also provides information useful for determining potential for offering technical collaboration, financial aid, and/or political support.« less

R and D ekes out an increase in FY 2015 budget request

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kramer, David

2014-05-01

With spending caps in place, President Obama proposes an off-budget fund to support additional R and D. NASA would ground a flying observatory, and DOE would sharply curtail its nonproliferation programs.

NNSA Program Develops the Next Generation of Nuclear Security Experts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brim, Cornelia P.; Disney, Maren V.

2015-09-02

NNSA is fostering the next generation of nuclear security experts is through its successful NNSA Graduate Fellowship Program (NGFP). NGFP offers its Fellows an exceptional career development opportunity through hands-on experience supporting NNSA mission areas across policy and technology disciplines. The one-year assignments give tomorrow’s leaders in global nuclear security and nonproliferation unparalleled exposure through assignments to Program Offices across NNSA.

Savannah River Site Environmental Report for 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arnett, M

The mission at the Savannah River Site (SRS) is focused primarily on support of the national defense, nonproliferation, and environmental cleanup. SRS-through its prime operating contractor, Westinghouse Savannah River Company-continues to maintain a comprehensive environmental monitoring program.

Selected Examples of LDRD Projects Supporting Test Ban Treaty Verification and Nonproliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, K.; Al-Ayat, R.; Walter, W. R.

The Laboratory Directed Research and Development (LDRD) Program at the DOE National Laboratories was established to ensure the scientific and technical vitality of these institutions and to enhance the their ability to respond to evolving missions and anticipate national needs. LDRD allows the Laboratory directors to invest a percentage of their total annual budget in cutting-edge research and development projects within their mission areas. We highlight a selected set of LDRD-funded projects, in chronological order, that have helped provide capabilities, people and infrastructure that contributed greatly to our ability to respond to technical challenges in support of test ban treatymore » verification and nonproliferation.« less

Report of a workshop on nuclear forces and nonproliferation Woodrow Wilson international center for scholars, Washington, DC October 28, 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pilat, Joseph F

2010-12-08

A workshop sponsored by the Los Alamos National Laboratory in cooperation with the Woodrow Wilson International Center for Scholars was held at the Wilson Center in Washington, DC, on October 28, 2010. The workshop addressed evolving nuclear forces and their impacts on nonproliferation in the context of the new strategic environment, the Obama Administration's Nuclear Posture Review and the 2010 NPT Review Conference. The discussions reflected the importance of the NPR for defining the role of US nuclear forces in dealing with 21st century threats and providing guidance for National Nuclear Security Administration (NNSA) and Department of Defense (DoD) programsmore » and, for many but not all participants, highlighted its role in the successful outcome of the NPT RevCon. There was widespread support for the NPR and its role in developing the foundations for a sustainable nuclear-weapon program that addresses nuclear weapons, infrastructure and expertise in the broader nonproliferation, disarmament and international security contexts. However, some participants raised concerns about its implementation and its long-term effectiveness and sustainability.« less

76 FR 65634 - Assistance to Foreign Atomic Energy Activities

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... Nuclear Nonproliferation (NA-20), Office of Nonproliferation and International Security (NA-24), 1000... Administrator for Defense Nuclear Nonproliferation, National Nuclear Security Administration, U.S. Department of...

Economic and Non-proliferation Policy Considerations of Uranium Enrichment in Brazil and Argentina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Short, Steven M.; Phillips, Jon R.; Weimar, Mark R.

2008-09-01

The nuclear development programs of both Argentina and Brazil have, since the 1970s, been premised on the desire for self-sufficiency and assurance of nuclear fuel supply. While military rivalry and mutual distrust led to nuclear weapons related development programs in the 1970s and 1980s, both countries have since terminated these programs. Furthermore, the governments of both countries have pledged their commitment to exclusively non-explosive use of nuclear energy and have signed the Non Proliferation Treaty (NPT). Utilizing rights provided for under the NPT, both Argentina and Brazil have nuclear fuel production facilities, with the notable exception of enrichment plants, thatmore » provide much of the current indigenous fuel requirements for their nuclear power plants. However, both countries are actively developing enrichment capability to fill this gap. The purpose of this report is to assess the economic basis and non-proliferation policy considerations for indigenous enrichment capability within the context of their desired self-sufficiency and to evaluate possible United States Government policy options.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hund, Gretchen; Kurzrok, Andrew J.

This paper investigates nonproliferation as a potential corporate sustainability value. It reviews the history of corporate sustainability, builds the case for nonproliferation as a sustainability value, and develops recommendations for the integration of nonproliferation into the frameworks of sustainability.

Arms Control and Nonproliferation: A Catalog of Treaties and Agreements

DTIC Science & Technology

2009-02-10

agreements to address U.S. security concerns. The United States and Soviet Union began to sign agreements limiting their strategic offensive nuclear ...era nuclear , chemical, and biological weapons. Through these cooperative efforts, the United States now allocates more than $1 billion each year to...spread of nuclear weapons. This regime, although suffering from some setbacks in recent years in Iran and North Korea, includes formal treaties

Director`s series on proliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bailey, K.C.; Price, M.E.

1994-10-17

This series is an occasional publication of essays on the topics of nuclear, chemical, biological, and missile proliferation. Essays contained in this document include: Key issues on NPT renewal and extension, Africa and nuclear nonproliferation, Kenya`s views on the NPT, Prospects for establishing a zone free of weapons of mass destruction in the middle east, effects of a special nuclear weapon materials cut-off convention, and The UK view of NPT renewal.

15 CFR 742.5 - Missile technology.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Country Chart (see supplement No. 1 to part 738 of the EAR). (2) The term “missiles” is defined as rocket systems (including ballistic missile systems, space launch vehicles, and sounding rockets) and unmanned... missile and space programs of the recipient country; (iv) The nonproliferation credentials of the...

Department of State Rewards Program Update and Technical Corrections Act of 2012

THOMAS, 112th Congress

Rep. Royce, Edward R. [R-CA-40

2012-02-17

House - 05/07/2012 Referred to the Subcommittee on Terrorism, Nonproliferation, and Trade. (All Actions) Notes: For further action, see S.2318, which became Public Law 112-283 on 1/15/2013. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

15 CFR 742.3 - Nuclear nonproliferation.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

15 CFR 742.3 - Nuclear nonproliferation.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

15 CFR 742.3 - Nuclear nonproliferation.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

15 CFR 742.3 - Nuclear nonproliferation.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

15 CFR 742.3 - Nuclear nonproliferation.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

78 FR 27373 - Proposed Agency Information Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-10

... amended (Pub. L. 83-703, 42 U.S.C. 2011 et seq.) and the Nuclear Non-Proliferation Act of 1978 (NNPA) (Pub... supports the United States Government's nuclear nonproliferation objectives by supporting civilian nuclear..., DC, on May 6, 2013. Anne Harrington, Principal Deputy Administrator, Defense Nuclear Nonproliferation...

Development of nonproliferation and assessment scenarios.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Finley, Melissa; Barnett, Natalie Beth

2005-10-01

The overall objective of the Nonproliferation and Assessments Scenario Development project is to create and analyze potential and plausible scenarios that would lead to an adversary's ability to acquire and use a biological weapon. The initial three months of funding was intended to be used to develop a scenario to demonstrate the efficacy of this analysis methodology; however, it was determined that a substantial amount of preliminary data collection would be needed before a proof of concept scenario could be developed. We have dedicated substantial effort to determine the acquisition pathways for Foot and Mouth Disease Virus, and similar processesmore » will be applied to all pathogens of interest. We have developed a biosecurity assessments database to capture information on adversary skill locales, available skill sets in specific regions, pathogen sources and regulations involved in pathogen acquisition from legitimate facilities. FY06 funding, once released, will be dedicated to data collection on acquisition, production and dissemination requirements on a pathogen basis. Once pathogen data has been collected, scenarios will be developed and scored.« less

3 CFR - Delegation of Authority Relating To Certain Functions Under Section 201 (B) of the United States...

Code of Federal Regulations, 2011 CFR

2011-01-01

... Functions Under Section 201 (B) of the United States-india Nuclear Cooperation Approval And Nonproliferation...-india Nuclear Cooperation Approval And Nonproliferation Enhancement Act (Public Law 110-369) Memorandum...) of the United States-India Nuclear Cooperation Approval and Nonproliferation Enhancement Act (Public...

78 FR 9768 - Bureau of International Security and Nonproliferation Imposition of Missile Sanctions on Two...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... DEPARTMENT OF STATE [Public Notice 8183] Bureau of International Security and Nonproliferation Imposition of Missile Sanctions on Two Chinese Foreign Persons AGENCY: Bureau of International Security and Nonproliferation, Department of State. ACTION: Notice. SUMMARY: A determination has been made that two foreign...

78 FR 9769 - Bureau of International Security and Nonproliferation Imposition of Nonproliferation Measures on...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... Imposition of Nonproliferation Measures on Chinese and Iranian Foreign Persons AGENCY: Bureau of... has determined that a number of Chinese and Iranian foreign persons have engaged in proliferation... that the following Chinese and Iranian foreign persons have engaged in proliferation activities that...

Arms Control and Nonproliferation: A Catalog of Treaties and Agreements

DTIC Science & Technology

2007-06-01

security concerns. The United States and Soviet Union began to sign agreements limiting their strategic offensive nuclear weapons in the early 1970s...Russian relationship. At the same time, however, the two sides began to cooperate on securing and eliminating Soviet-era nuclear , chemical, and biological...former Soviet Union. The United States is also a leader of an international regime that attempts to limit the spread of nuclear weapons. This regime

The Creation of a Contagious H5N1 Influenza Virus: Implications for the Education of Life Scientists

PubMed Central

Novossiolova, Tatyana; Minehata, Masamichi; Dando, Malcolm

2012-01-01

The paper contends that the ongoing controversy surrounding the creation of a contagious H5N1 influenza virus has already exposed the severe limitations of the possibility of preventing the hostile misuse of the life sciences by dint of oversight of proposals and publications. It further argues that in order to prevent the potential wholesale militarisation of the life sciences, it is essential that life scientists become aware of their responsibilities within the context of the Biological and Toxin Weapons Convention (BTWC) and actively contribute their expertise to strengthening the biological weapons non-proliferation regime . PMID:22984642

Nonproliferation and Threat Reduction Assistance: U.S. Programs in the Former Soviet Union

DTIC Science & Technology

2011-04-26

large - scale former BW-related facilities so that they can perform peaceful research issues such as infectious diseases. The Global Threat Reduction...indicated that it may not pursue the MOX program to eliminate its plutonium, opting instead for the construction of fast breeder reactors that could...burn plutonium directly for energy production. The United States might not fund this effort, as many in the United States argue that breeder reactors

Results in Developing an Engineering Degree Program in Safeguards and Security of Nuclear Materials at Moscow Engineering Physics Institute

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kryuchkov, Eduard F.; Geraskin, Nikolay I.; Killinger, Mark H.

The world’s first master’s degree program in nuclear safeguards and security, established at Moscow Engineering Physics Institute (MEPhI), has now graduated nine classes of students. Most of the graduates have gone on to work at government agencies, research organizations, or obtain their PhD. In order to meet the demand for safeguards and security specialists at nuclear facilities, MEPhI established a 5½ year engineering degree program that provides more hands-on training desired by facilities. In February 2004, the first students began their studies in the new discipline Nuclear Material Safeguards and Nonproliferation. This class, as well as other subsequent classes, includedmore » students who started the program in their third year of studies, as the first 2½ years consists of general engineering curriculum. Fourteen students made up the first graduating class, receiving their engineering degrees in February 2007. The topics addressed in this paper include specific features of the program caused by peculiarities of Russian education legislation and government quality control of academic education. This paper summarizes the main joint actions undertaken by MEPhI and the US National Laboratories in conjunction with the U.S. Department of Energy, to develop the engineering degree program. Also discussed are the program’s specific training requirements, student internships, and job placement. The paper concludes with recommendations from a recent international seminar on nonproliferation education and training.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shipwash, Jacqueline L; Kovacic, Donald N

Infrastructure Preparedness and Vietnam Jacqueline L. Shipwash and Donald N. Kovacic (shipwashjl@ornl.gov, 865-241-9129, and kovacicdn@ornl.gov, 865-576-1459) Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 The global expansion of nuclear energy will require international cooperation to ensure that nuclear materials, facilities, and sensitive technologies are not diverted to non-peaceful uses. Developing countries will require assistance to ensure the effective regulation, management, and operation of their nuclear programs to achieve best practices in nuclear nonproliferation. A developing nation has many hurdles to pass before it can give assurances to the international community that it is capable of implementing a sustainable nuclear energymore » program. In August of this year, the U.S. Department of Energy and the Ministry of Science and Technology of the Socialist Republic of Vietnam signed an arrangement for Information Exchange and Cooperation on the Peaceful Uses of Nuclear Energy. This event signals an era of cooperation between the U.S. and Vietnam in the area of nuclear nonproliferation. This paper will address how DOE is supporting the development of secure and sustainable infrastructures in emerging nuclear nations such as Vietnam.« less

The Nuclear Non-Proliferation Treaty: Regulating Nuclear Weapons around the World

ERIC Educational Resources Information Center

Middleton, Tiffany Willey

2010-01-01

In May 2010, scientists, national security experts, and state delegates from nations around the world will convene in New York for the 2010 Nuclear Non-Proliferation Treaty Review Conference. They will review current guidelines for nuclear testing and possession of nuclear weapons in accordance with the Nuclear Non-Proliferation Treaty of 1968,…

Identifying, Visualizing, and Fusing Social Media Data to Support Nonproliferation and Arms Control Treaty Verification: Preliminary Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gastelum, Zoe N.; Cramer, Nicholas O.; Benz, Jacob M.

While international nonproliferation and arms control verification capabilities have their foundations in physical and chemical sensors, state declarations, and on-site inspections, verification experts are beginning to consider the importance of open source data to complement and support traditional means of verification. One of those new, and increasingly expanding, sources of open source information is social media, which can be ingested and understood through social media analytics (SMA). Pacific Northwest National Laboratory (PNNL) is conducting research to further our ability to identify, visualize, and fuse social media data to support nonproliferation and arms control treaty verification efforts. This paper will describemore » our preliminary research to examine social media signatures of nonproliferation or arms control proxy events. We will describe the development of our preliminary nonproliferation and arms control proxy events, outline our initial findings, and propose ideas for future work.« less

Law, Policy and Nonproliferation Project Events and Workshops: Key Themes, Results and Related Materials 2008 - 2009

DTIC Science & Technology

2010-04-01

biological precursors are obtained legally from legitimate corporations, these suppliers should incorporate some sort of chemical or genetic “barcode...traditionally come under the rubric of limited engagement, especially as such policy evolved during the Cold War between the US and USSR. With the end...information that may enable access to dual-use technology. A “bar-coding” procedure, by which a genetic sequence or chemical signature is used to

Penaid Nonproliferation: Hindering the Spread of Countermeasures Against Ballistic Missile Defenses

DTIC Science & Technology

2014-01-01

50 Penaid Nonproliferation: Hindering the Spread of Countermeasures Against Ballistic Missile Defenses 42 /2010! Plume Signature Control...and Richard Speier, “Penaid Nonproliferation: Analysis and Recommendations,” briefing, Veridian Corp., Arlington, Va., June 29, 2000. “ Missile ...is a nonprofit institution that helps improve policy and decisionmaking through research and analysis . This electronic document was made available

Nonproliferation and Threat Reduction Assistance: U.S, Programs in the Former Soviet Union

DTIC Science & Technology

2008-03-26

reconfigure its large - scale former BW-related facilities so that they can perform peaceful research issues such as infectious diseases. For FY2004, the Bush...program to eliminate its plutonium, opting instead for the construction of fast breeder reactors that could burn plutonium directly for energy production...The United States might not fund this effort, as many in the United States argue that breeder reactors , which produce more plutonium than they

Nonproliferation and Threat Reduction Assistance: U.S. Programs in the Former Soviet Union

DTIC Science & Technology

2012-03-06

The March 1995 nerve agent attack in the Tokyo subway system by the Aum Shinryo cult raised the profile of this type of threat. 19 The report went...had not yet produced any commercial successes . DOE responded by stating that IAP had temporarily employed thousands of scientists in around 170...continued, coordinated success for the programs requires “active political engagement at the White House, cabinet, and sub-cabinet political appointee

77 FR 43413 - Imposition of Nonproliferation Measures on Five Syrian Entities

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-24

... Program Management, Office of Foreign Assets Control, Department of the Treasury (202-622-2500). On U.S... imposition of measures pursuant to sections 4(b), 4(c), and 4(d) of Executive Order 12938: Business Lab...) transfers of U.S.-origin defense articles and defense services from foreign destinations to the above-named...

Will Russian Scientists Go Rogue? A Survey on the Threat and the Impact of Western Assistance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ball, D Y; Gerber, T P

2004-12-27

The collapse of the Soviet Union sparked fears throughout the world that rogue nations and terrorist organizations would gain access to weapons of mass destruction (WMD). One specific concern has been 'WMD brain drain.' Russians with knowledge about nuclear, chemical, and biological weapons could now depart to any country of their choice, including rogue nations seeking to produce WMD. Meanwhile, Russian science fell into a protracted crisis, with plummeting salaries, little funding for research, and few new recruits to science. These developments increased both the incentives and the opportunities for scientists to sell their knowledge to governments and terrorist organizationsmore » with hostile intentions toward the United States. Recognizing the threat of WMD brain drain from Russia, the United States, and other governments implemented a host of programs designed to reduce the risk. Despite, or perhaps partly because of, massive assistance from the West to prevent scientists with WMD knowledge from emigrating, the threat of Russian WMD brain drain has recently faded from view. Yet we have seen no evidence that these programs are effective and little systematic assessment of the current threat of WMD migration. Our data from an unprecedented survey of 602 Russian physicists, biologists, and chemists suggest that the threat of WMD brain drain from Russia should still be at the forefront of our attention. Roughly 20 percent of Russian physicists, biologists, and chemists say they would consider working in rogue nations such as North Korea, Iran, Syria, or Iraq (still considered a rogue state at the time of the survey). At the same time, the data reveal that U.S. and Western nonproliferation assistance programs work. They significantly reduce the likelihood that Russian scientists would consider working in these countries. Moreover, Russian grants do not reduce scientists' propensity to 'go rogue'. These survey findings have clear policy implications: the U.S. and its allies must continue to adequately fund nonproliferation assistance programs rather than hastily declare victory. The U.S. should remain engaged with former Soviet WMD scientists until they are willing and able to find support for their research from competitive, civilian-oriented, privately funded projects. Otherwise, we run a great risk that WMD expertise will migrate from the former Soviet Union to countries or organizations that harbor hostile intentions toward the U.S. Assistance programs work to reduce the threat of WMD brain drain, but their task is not complete. Now is not the time to pull back.« less

Adhesion Molecule Expression and Function of Primary Endothelial Cells in Benign and Malignant Tissues Correlates with Proliferation

PubMed Central

Sievert, Wolfgang; Tapio, Soile; Breuninger, Stephanie; Gaipl, Udo; Andratschke, Nicolaus; Trott, Klaus-Rüdiger; Multhoff, Gabriele

2014-01-01

Background Comparative analysis of the cellular biology of the microvasculature in different tissues requires the availability of viable primary endothelial cells (ECs). This study describes a novel method to isolate primary ECs from healthy organs, repair blastemas and tumors as examples of non-proliferating and proliferating benign and malignant tissues and their functional characterization. Methodology/Principal Findings Single cell suspensions from hearts, lungs, repair blastemas and tumors were incubated consecutively with an anti-CD31 antibody and magnetic micro-beads, coupled to a derivative of biotin and streptavidin, respectively. Following magnetic bead separation, CD31-positive ECs were released by biotin-streptavidin competition. In the absence of micro-beads, ECs became adherent to plastic surfaces. ECs from proliferating repair blastemas and tumors were larger and exhibited higher expression densities of CD31, CD105 and CD102 compared to those from non-proliferating normal tissues such as heart and lung. The expression density of CD34 was particularly high in tumor-derived ECs, and that of CD54 and CD144 in ECs of repair blastemas. Functionally, ECs of non-proliferating and proliferating tissues differed in their capacity to form tubes in matrigel and to align under flow conditions. Conclusions/Significance This method provides a powerful tool to generate high yields of viable, primary ECs of different origins. The results suggest that an altered expression of adhesion molecules on ECs in proliferating tissues contribute to loss of EC function that might cause a chaotic tumor vasculature. PMID:24632811

Suggestions for Strategic Planning for the Office of Nonproliferation Research and Engineering

DTIC Science & Technology

2002-01-01

The Office of Nonproliferation Research and Engineering, part of the recently formed National Nuclear Security Administration within the Department...of Energy, conducts wide-ranging research for diverse end users at the federal and local level. As such, the Office faces a number of challenges in...planning methods. This report grew out of support provided to an advisory committee for the Office of Nonproliferation and National Security, an

Special Issue on University Nonproliferation Education and Training Introduction.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leek, K. M.

2006-07-31

Nonproliferation, like many aspects of security, has not played out as many expected following the end of the cold war. The peace dividend has been elusive in many countries. The notion that the world would become a safer and more secure place as nuclear weapons stockpiles were reduced has been trumped by the rise in international terrorism. Hopes that nuclear weapons would lose their salience as markers of elite status among nations along with pressures to acquire them have been dashed. The drive by some countries and terrorist groups to acquire nuclear weapons has not diminished, and the threat ofmore » proliferation has increased. At the level of the nation state, the Nonproliferation Treaty (NPT) itself is under pressure as more nations acquire nuclear weapons, de facto weapons states fail to join, and nations that want to acquire them leave or threaten to leave. At the sub-state level, the convergence of terrorism and weapons of mass destruction (WMD) has introduced an element of uncertainty into nonproliferation that is unprecedented. Another feature of the post-cold war era that has taken many by surprise is the continued, and growing need for trained specialists in nonproliferation and nuclear materials management. Contained within the notion of disarmament and reduced strategic importance of nuclear weapons was the expectation of a diminishing workforce of trained nonproliferation and nuclear materials specialists. Events have overtaken this assumption.« less

A Sustainable WMD Nonproliferation Strategy for East Africa: Connecting the WMD Nonproliferation Agenda with Local Border Security Needs to Achieve Mutually Beneficial Outcomes

DTIC Science & Technology

2014-01-01

Government of Kenya stakeholders with providing a framework for analysis by engaging with a wide range of border security experts from key donor states...holistic national border security action plan and gap analysis were necessary to simultaneously deal with the global WMD nonproliferation agenda and...efforts from a research and analysis vantage point. The underlying idea was that Kenya, through this border security action plan and gap analysis , would

75 FR 76653 - Export Control Modernization: Strategic Trade Authorization License Exception

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-09

...); nuclear nonproliferation (NP); regional stability (RS); encryption items (EI); crime control (CC) (but not... weapons (CB); nuclear nonproliferation (NP); regional stability (RS); encryption items (EI); crime control...

The European Safeguards Research and Development Association Addresses Safeguards and Nonproliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Janssens-Maenhout, Greet; Kusumi, R.; Daures, Pascal A.

2010-06-16

The renaissance of efforts to expand the use of nuclear energy requires the parallel development of a renewed and more sophisticated work force. Growth in the nuclear sector with high standard of safety, safeguards and security requires skilled staff for design, operations, inspections etc. High-quality nuclear technology educational programs are diminished from past years, and the ability of universities to attract students and to meet future staffing requirements of the nuclear industry is becoming seriously compromised. Thus, education and training in nuclear engineering and sciences is one of the cornerstones for the nuclear sector. Teaching in the nuclear field stillmore » seems strongly influenced by national history but it is time to strengthen resources and collaborate. Moreover with the current nuclear security threats it becomes critical that nuclear technology experts master the basic principles not only of safety, but also of nuclear safeguards, nonproliferation and nuclear security. In Europe the European Nuclear Education Network (ENEN) Association has established the certificate 'European Master of Science in Nuclear Engineering (EMSNE)' as the classic nuclear engineering program covering reactor operation and nuclear safety. However, it does not include courses on nonproliferation, safeguards, or dual-use technologies. The lack of education in nuclear safeguards was tackled by the European Safeguards Research and Development Association (ESARDA), through development and implementation of safeguards course modules. Since 2005 the ESARDA Working Group, called the Training and Knowledge Management Working Group, (TKMWG) has worked with the Joint Research Centre (JRC) in Ispra, Italy to organize a Nuclear Safeguards and Nonproliferation course. This five-day course is held each spring at the JRC, and continues to show increasing interest as evidenced by the positive responses of international lecturers and students. The standard set of lectures covers a broad range of subjects, including nuclear material accountancy principles, legal definitions and the regulatory base and inspection tools and techniques. This 60% core part is given by representatives from regulatory bodies (The International Atomic Energy Agency (IAEA), Institute for Radiological Protection and Nuclear Safety, Directorate General for Nuclear Energy and Transport), industry (AREVA, British Nuclear Group), and research (Stockholm University, Hamburg University, Joint Research Centre-Institute of Transuranic Elements, and Joint Research Centre-Institute for the Protection of the Citizen). The remaining part is completed with topical lectures addressed by invited lecturers, such as from Pacific Northwest National Laboratory and the IAEA addressing topics of physical protection, illicit trafficking, the Iraq case study, exercises, including satellite imagery interpretation etc. With this structure of a stable core plus a variable set of invited lectures, the course will remain sustainable and up-to-date. A syllabus provides the students a homogeneous set of information material in nuclear safeguards and nonproliferation matters at the European and international level. In this way, the ESARDA TKMWG aims to contribute to a two-fold scientific-technical and political-juridical education and training.« less

15 CFR 750.3 - Review of license applications by BIS and other government agencies and departments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... items controlled for national security, missile technology, nuclear nonproliferation, and chemical and... primarily with items controlled for national security, nuclear nonproliferation, missile technology...

15 CFR 750.3 - Review of license applications by BIS and other government agencies and departments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... items controlled for national security, missile technology, nuclear nonproliferation, and chemical and... primarily with items controlled for national security, nuclear nonproliferation, missile technology...

15 CFR 750.3 - Review of license applications by BIS and other government agencies and departments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... items controlled for national security, missile technology, nuclear nonproliferation, and chemical and... primarily with items controlled for national security, nuclear nonproliferation, missile technology...

International Safeguards Technology and Policy Education and Training Pilot Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dreicer, M; Anzelon, G A; Essner, J T

2009-06-16

A major focus of the National Nuclear Security Administration-led Next Generation Safeguards Initiative (NGSI) is the development of human capital to meet present and future challenges to the safeguards regime. An effective university-level education in safeguards and related disciplines is an essential element in a layered strategy to rebuild the safeguards human resource capacity. NNSA launched two pilot programs in 2008 to develop university level courses and internships in association with James, Martin Center for Nonproliferation Studies (CNS) at the Monterey Institute of International Studies (MIIS) and Texas A&M University (TAMU). These pilot efforts involved 44 students in total andmore » were closely linked to hands-on internships at Los Alamos National Laboratory (LANL) and Lawrence Livermore National Laboratory (LLNL). The Safeguards and Nuclear Material Management pilot program was a collaboration between TAMU, LANL, and LLNL. The LANL-based coursework was shared with the students undertaking internships at LLNL via video teleconferencing. A weeklong hands-on exercise was also conducted at LANL. A second pilot effort, the International Nuclear Safeguards Policy and Information Analysis pilot program was implemented at MIIS in cooperation with LLNL. Speakers from MIIS, LLNL, and other U.S. national laboratories (LANL, BNL) delivered lectures for the audience of 16 students. The majority of students were senior classmen or new master's degree graduates from MIIS specializing in nonproliferation policy studies. The two pilots programs concluded with an NGSI Summer Student Symposium, held at LLNL, where 20 students participated in LLNL facility tours and poster sessions. The value of bringing together the students from the technical and policy pilots was notable and will factor into the planning for the continued refinement of the two programs in the coming years.« less

The Nuclear Nonproliferation Treaty in Context

NASA Astrophysics Data System (ADS)

Davenport, Kelsey

2017-01-01

The 1968 Nuclear Nonproliferation Treaty (NPT) is the cornerstone of multilateral efforts to prevent the spread of nuclear weapons and promote efforts toward complete disarmament. In the grand bargain of the NPT, states foreswore pursuit of nuclear weapons in exchange for access to nuclear technology and limited nuclear arsenals to the five states (China, France, Russia, the United Kingdom and the United States) that tested such weapons before the NPT's conception. Now in its seventh decade, the NPT regime is embraced by the vast majority of the world's nations and is viewed as a critical element of international security. However, despite past successes in halting efforts in several states to pursue nuclear weapons, near universal adherence, and only one withdrawal (North Korea), the NPT regime is at a critical crossroads. The treaty has proven unable to adapt to new challenges, such as emerging technologies that threaten operational strategic realities, the devolution of state authority to non-state actors and institutions, and growing dissatisfaction with slow pace of nuclear disarmament. Additionally, the treaty leaves open critical questions, including whether or not state parties have the `right' to pursue technologies that allow for domestic production of fuels for nuclear reactors and if modernization programs for nuclear warheads are inconsistent with the treaty. If these questions remain unresolved, the international community will find itself ill prepared to confront emerging proliferation challenges and the NPT, the linchpin of international nonproliferation and disarmament efforts, may begin to erode.

DETERMINATION OF RELATIVE IMPORTANCE OF NONPROLIFERATION FACTORS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richard Metcalf

2009-07-01

Methodologies to determine the proliferation resistance (PR) of nuclear facilities often rely on either expert elicitation, a resource-intensive approach without easily reproducible results, or numeric evaluations, which can fail to take into account the institutional knowledge and expert experience of the nonproliferation community. In an attempt to bridge the gap and bring the institutional knowledge into numeric evaluations of PR, a survey was conducted of 33 individuals to find the relative importance of a set of 62 nonproliferation factors, subsectioned into groups under the headings of Diversion, Transportation, Transformation, and Weaponization. One third of the respondents were self-described nonproliferation professionals,more » and the remaining two thirds were from secondary professions related to nonproliferation, such as industrial engineers or policy analysts. The factors were taken from previous work which used multi-attribute utility analysis with uniform weighting of attributes and did not include institutional knowledge. In both expert and non-expert groups, all four headings and the majority of factors had different relative importance at a confidence of 95% (p=0.05). This analysis and survey demonstrates that institutional knowledge can be brought into numeric evaluations of PR, if there is a sufficient investment of resources made prior to the evaluation.« less

Non-Proliferation, the IAEA Safeguards System, and the importance of nuclear material measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stevens, Rebecca S.

2017-09-18

The objective of this project is to explain the contribution of nuclear material measurements to the system of international verification of State declarations and the non-proliferation of nuclear weapons.

Non-proliferation, safeguards, and security for the fissile materials disposition program immobilization alternatives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duggan, R.A.; Jaeger, C.D.; Tolk, K.M.

1996-05-01

The Department of Energy is analyzing long-term storage and disposition alternatives for surplus weapons-usable fissile materials. A number of different disposition alternatives are being considered. These include facilities for storage, conversion and stabilization of fissile materials, immobilization in glass or ceramic material, fabrication of fissile material into mixed oxide (MOX) fuel for reactors, use of reactor based technologies to convert material into spent fuel, and disposal of fissile material using geologic alternatives. This paper will focus on how the objectives of reducing security and proliferation risks are being considered, and the possible facility impacts. Some of the areas discussed inmore » this paper include: (1) domestic and international safeguards requirements, (2) non-proliferation criteria and measures, (3) the threats, and (4) potential proliferation, safeguards, and security issues and impacts on the facilities. Issues applicable to all of the possible disposition alternatives will be discussed in this paper. However, particular attention is given to the plutonium immobilization alternatives.« less

University Engagement at INL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morrell, Sean Robert; Rynes, Amanda Renee

2014-07-01

There are currently over 900 facilities in over 170 countries which fall under International Atomic Energy Agency (IAEA) safeguards. As additional nations look to purse civilian nuclear programs or to expand infrastructure already in place, the number of reactors and accompanying facilities as well as the quantity of material has greatly increased. Due to the breadth of the threat and the burden placed on the IAEA as nuclear applications expand, it has become increasingly important that safeguards professionals have a strong understanding of both the technical and political aspects of nonproliferation starting early in their career. To begin overcoming thismore » challenge, Idaho National Laboratory, has partnered with local universities to deliver a graduate level nuclear engineering course that covers both aspects of the field with a focus on safeguards applications. To date over 60 students across multiple disciplines have participated in this course with many deciding to transition into a nonproliferation area of focus in both their academic and professional careers.« less

Institutional plan FY 1999--FY 2004

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-10-01

Los Alamos has a well-defined and nationally important mission: to reduce the global nuclear danger. This central national security mission consists of four main elements: stockpile stewardship, nuclear materials management, nonproliferation and arms control, and cleanup of the environmental legacy of nuclear weapons activities. The Laboratory provides support for and ensures confidence in the nation`s nuclear stockpile without nuclear testing. This challenge requires the Laboratory to continually hone its scientific acumen and technological capabilities to perform this task reliably using an interdisciplinary approach and advanced experimental and modeling techniques. In the last two National Defense Authorization Acts, Congress identified themore » need to protect the nation from the proliferation of weapons of mass destruction, which includes nuclear, chemical, and biological weapons, and their potential use by terrorists. Los Alamos is applying multidisciplinary science and engineering skills to address these problems. In addition, the Laboratory`s critical programmatic roles in stockpile stewardship and threat reduction are complemented by its waste management operations and environmental restoration work. Information on specific programs is available in Section 2 of this document.« less

Irans Nuclear Program: Tehrans Compliance with International Obligations

DTIC Science & Technology

2016-04-07

ratified the nuclear Nonproliferation Treaty (NPT) in 1970. Article III of the treaty requires non-nuclear- weapon states-parties 1 to accept...concern that Tehran is pursuing nuclear weapons . Tehran’s construction of gas centrifuge uranium enrichment facilities is currently the main source...uranium (HEU), which is one of the two types of fissile material used in nuclear weapons . HEU can also be used as fuel in certain types of nuclear

Irans Nuclear Program: Tehrans Compliance with International Obligations

DTIC Science & Technology

2016-03-03

ratified the nuclear Nonproliferation Treaty (NPT) in 1970. Article III of the treaty requires non-nuclear- weapon states-parties 1 to accept...concern that Tehran is pursuing nuclear weapons . Tehran’s construction of gas centrifuge uranium enrichment facilities is currently the main source...uranium (HEU), which is one of the two types of fissile material used in nuclear weapons . HEU can also be used as fuel in certain types of nuclear

Nonproliferation Sanctions

DTIC Science & Technology

2001-01-01

some laws may exempt the member government from sanctions-is increasing. But the U.S. role -or potential role -as a trade partner is increasing. Meanwhile...involved U.S. legislation passed after the triggering events. 14 For a discussion of the role of sanctions in the array of foreign policy instruments...contract sanctity and the role of the sanctions in otherwise blocking U.S. military or civilian programs. However, the essence of all the waiver

New Brunswick Laboratory progress report, October 1994--September 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The mission of the New Brunswick Laboratory (NBL) of the A. S. Department of Energy (DOE) is to serve as the National Certifying Authority for nuclear reference materials and to provide an independent Federal technical staff and laboratory resource performing nuclear material measurement, safeguards, and non-proliferation functions in support of multiple program sponsors. This annual report describes accomplishments achieved in carrying out NBL`s assigned missions.

75 FR 28673 - Bureau of Verification, Compliance, and Implementation; Termination of Measures Against a Russian...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-21

... Iran, North Korea, and Syria Nonproliferation Act. DATES: Effective Date: May 21, 2010. FOR FURTHER.... SUPPLEMENTARY INFORMATION: Pursuant to Section 4 of the Iran, North Korea, and Syria Nonproliferation Act (Pub...

Nonproliferation and Threat Reduction Assistance: U.S. Programs in the Former Soviet Union

DTIC Science & Technology

2009-07-31

seeks to help Russia reconfigure its large - scale former BW-related facilities so that they can perform peaceful research issues such as infectious...opting instead for the construction of fast breeder reactors that could burn plutonium directly for energy production. The United States might not fund...this effort, as many in the United States argue that breeder reactors , which produce more plutonium than they consume, would undermine

Iran's Relations to the East: Nonproliferation and Regional Security in a Changing Southwest Asia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tehsin, Muhammad

This study attempts to answer the following questions: would a successful JPOA result in nuclear nonproliferation and regional security in Southwest Asia; and could the Middle East and South Asia work together to contain the threat of Salafi jihadism?

76 FR 51357 - Notice of Availability: American Assured Fuel Supply

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... nonproliferation objectives by supporting civil nuclear energy development while minimizing proliferation risks... to the Atomic Energy of 1954, as amended (Pub. L. 83-703), and the Nuclear Non-Proliferation Act of... the International Atomic Energy Agency's (IAEA) International Nuclear Fuel Bank (INFB) initiative...

3 CFR - Certifications Pursuant to Section 104 of the United States-India Nuclear Cooperation Approval...

Code of Federal Regulations, 2011 CFR

2011-01-01

... States-India Nuclear Cooperation Approval and Nonproliferation Enhancement Act Regarding the Safeguards Agreement Between India and the International Atomic Energy Agency Presidential Documents Other Presidential... of the United States-India Nuclear Cooperation Approval and Nonproliferation Enhancement Act...

Use of Social Media to Target Information-Driven Arms Control and Nonproliferation Verification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kreyling, Sean J.; Williams, Laura S.; Gastelum, Zoe N.

There has been considerable discussion within the national security community, including a recent workshop sponsored by the U.S. State Department, about the use of social media for extracting patterns of collective behavior and influencing public perception in areas relevant to arms control and nonproliferation. This paper seeks to explore if, and how, social media can be used to supplement nonproliferation and arms control inspection and monitoring activities on states and sites of greatest proliferation relevance. In this paper, we set the stage for how social media can be applied in this problem space and describe some of the foreseen challenges,more » including data validation, sources and attributes, verification, and security. Using information analytics and data visualization capabilities available at Pacific Northwest National Laboratory (PNNL), we provide graphical examples of some social media "signatures" of potential relevance for nonproliferation and arms control purposes. We conclude by describing a proposed case study and offering recommendations both for further research and next steps by the policy community.« less

Former Nonproliferation Graduate Fellow Served at U.S. Mission

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brim, Cornelia P.

2014-10-01

Because of her training and professional experiences, Rosalyn Leitch, a Security Specialist at Pacific Northwest National Laboratory and former Nonproliferation Graduate Fellow with NIS (2012-2013) was able to transition into temporary assignment as UNVIE Acting Nuclear Security Attaché from November 2013 through February 2014.

Supporting the President's Arms Control and Nonproliferation Agenda: Transparency and Verification for Nuclear Arms Reductions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doyle, James E; Meek, Elizabeth

2009-01-01

The President's arms control and nonproliferation agenda is still evolving and the details of initiatives supporting it remain undefined. This means that DOE, NNSA, NA-20, NA-24 and the national laboratories can help define the agenda, and the policies and the initiatives to support it. This will require effective internal and interagency coordination. The arms control and nonproliferation agenda is broad and includes the path-breaking goal of creating conditions for the elimination of nuclear weapons. Responsibility for various elements of the agenda will be widely scattered across the interagency. Therefore an interagency mapping exercise should be performed to identify the keymore » points of engagement within NNSA and other agencies for creating effective policy coordination mechanisms. These can include informal networks, working groups, coordinating committees, interagency task forces, etc. It will be important for NA-20 and NA-24 to get a seat at the table and a functional role in many of these coordinating bodies. The arms control and nonproliferation agenda comprises both mature and developing policy initiatives. The more mature elements such as CTBT ratification and a follow-on strategic nuclear arms treaty with Russia have defined milestones. However, recent press reports indicate that even the START follow-on strategic arms pact that is planned to be complete by the end of 2009 may take significantly longer and be more expansive in scope. The Russians called for proposals to count non-deployed as well as deployed warheads. Other elements of the agenda such as FMCT, future bilateral nuclear arms reductions following a START follow-on treaty, nuclear posture changes, preparations for an international nuclear security summit, strengthened international safeguards and multilateral verification are in much earlier stages of development. For this reason any survey of arms control capabilities within the USG should be structured to address potential needs across the near-term (1-4) years and longer-term (5-10) years planning horizons. Some final observations include acknowledging the enduring nature of several key objectives on the Obama Administration's arms control and nonproliferation agenda. The CTBT, FMCT, bilateral nuclear arms reductions and strengthening the NPT have been sought by successive U.S. Administrations for nearly thirty years. Efforts towards negotiated arms control, although de-emphasized by the G.W. Bush Administration, have remained a pillar of U.S. national security strategy for decades and are likely to be of enduring if not increasing importance for decades to come. Therefore revitalization and expansion of USG capabilities in this area can be a positive legacy no matter what near-term arms control goals are achieved over the next four years. This is why it is important to reconstruct integrated bureaucratic, legislative, budgetary and diplomatic strategies to sustain the arms control and nonproliferation agenda. In this endeavor some past lessons must be taken to heart to avoid bureaucratic overkill and keep interagency policy-making and implementation structures lean and effective. On the Technical side a serious, sustained multilateral program to develop, down select and performance test nuclear weapons dismantlement verification technologies and procedures should be immediately initiated. In order to make this happen the United States and Russia should join with the UK and other interested states in creating a sustained, full-scale research and development program for verification at their respective nuc1ear weapons and defense establishments. The goals include development of effective technologies and procedures for: (1) Attribute measurement systems to certify nuclear warheads and military fissile materials; (2) Chain-of-custody methods to track items after they are authenticated and enter accountability; (3) Transportation monitoring; (4) Storage monitoring; (5) Fissile materials conversion verification. The remainder of this paper focuses on transparency and verification for nuclear arms and fissile material reductions.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, T.H.

The proliferation of surface-to-surface missiles (SSMs) and weapons of mass destruction has become one of the more serious security threats to post-Cold War peace. This dissertation examines the history of proliferation within the Middle East by focusing primarily on three trend-setting countries: Israel, Syria and Iran. Building on the theoretical framework established by Lewis A. Dunn and Herman Kahn, this dissertation examines why and how Israel, Syria and Iran have procured SSMs and weapons of mass destruction. The author also includes an analysis of tactical missile defenses and their impact on proliferation trends. The final section investigates the numerous armsmore » control treaties and supplier cartels designed to halt or slow the pace of unconventional weapons proliferation. In many instances, Iraq serves as the primary example of how well-intentioned nonproliferation efforts have fallen short. This dissertation reveals some of the major flaws in these regimes while proposing necessary improvements if nonproliferation efforts are to succeed. In conclusion, this dissertation returns to the expanded Dunn-Kahn nuclear proliferation model. By categorizing the various reasons as to why countries choose to procure unconventional weapons, a more successful nonproliferation policy can be constructed. However, this dissertation warns that without political solutions to long-term disputes in the region, western-imposed nonproliferation regimes will fail. Thus, nonproliferation policies must be accompanied or preceded by a vigorous diplomatic and political effort to solve seemingly intractable differences.« less

Detection for Nuclear Nonproliferation

DOE PAGES

Pozzi, Sara A.; Hamel, Michael C.; Polack, J. Kyle; ...

2016-11-13

The detection and characterization of special nuclear materials is a high priority area for applications in nuclear safeguards and nonproliferation. We are developing new instruments based on organic scintillators to detect and characterize the emissions from special nuclear materials. This paper describes some of the gaps and challenges in nuclear safeguards and proposed approaches.

15 CFR 750.3 - Review of license applications by BIS and other government agencies and departments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... items controlled for national security, missile technology, nuclear nonproliferation, and chemical and... primarily with items controlled for national security, nuclear nonproliferation, missile technology... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Review of license applications by BIS...

15 CFR 750.3 - Review of license applications by BIS and other government agencies and departments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... items controlled for national security, missile technology, nuclear nonproliferation, and chemical and... primarily with items controlled for national security, nuclear nonproliferation, missile technology... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Review of license applications by BIS...

76 FR 30986 - Bureau of International Security and Nonproliferation; Imposition of Nonproliferation Measures...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... control lists (Missile Technology Control Regime, Australia Group, Chemical Weapons Convention, Nuclear... the development of weapons of mass destruction (WMD) or cruise or ballistic missile systems. The... contribution to WMD or cruise or ballistic missile systems, (b) other items with the potential of making such a...

Applications Using High Flux LCS gamma-ray Beams: Nuclear Security and Contributions to Fukushima

NASA Astrophysics Data System (ADS)

Fujiwara, Mamoru

2014-09-01

Nuclear nonproliferation and security are an important issue for the peaceful use of nuclear energy. Many countries now collaborate together for preventing serious accidents from nuclear terrorism. Detection of hidden long-lived radioisotopes and fissionable nuclides in a non-destructive manner is useful for nuclear safeguards and management of nuclear wastes as well as nuclear security. After introducing the present situation concerning the nuclear nonproliferation and security in Japan, we plan to show the present activities of JAEA to detect the hidden nuclear materials by means of the nuclear resonance fluorescence with energy-tunable, monochromatic gamma-rays generated by Laser Compton Scattering (LCS) with an electron beam. The energy recovery linac (ERL) machine is now under development with the KEK-JAEA collaboration for realizing the new generation of gamma-ray sources. The detection technologies of nuclear materials are currently developed using the existing electron beam facilities at Duke University and at NewSubaru. These developments in Japan will contribute to the nuclear security program in Japan and to the assay of melted nuclear fuels in the Fukushima Daiichi nuclear power plants.

Using Rose and Compass for Authentication

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G

2009-07-09

Many recent non-proliferation software projects include a software authentication component. In this context, 'authentication' is defined as determining that a software package performs only its intended purpose and performs that purpose correctly and reliably over many years. In addition to visual inspection by knowledgeable computer scientists, automated tools are needed to highlight suspicious code constructs both to aid the visual inspection and to guide program development. While many commercial tools are available for portions of the authentication task, they are proprietary, and have limited extensibility. An open-source, extensible tool can be customized to the unique needs of each project. ROSEmore » is an LLNL-developed robust source-to-source analysis and optimization infrastructure currently addressing large, million-line DOE applications in C, C++, and FORTRAN. It continues to be extended to support the automated analysis of binaries (x86, ARM, and PowerPC). We continue to extend ROSE to address a number of security specific requirements and apply it to software authentication for non-proliferation projects. We will give an update on the status of our work.« less

The Midlife Crisis of the Nuclear Nonproliferation Treaty

NASA Astrophysics Data System (ADS)

Pella, Peter

2016-03-01

The Nuclear Nonproliferation Treaty (NPT) has been the principal legal barrier to prevent the spread of nuclear weapons for the past forty-five years. It promotes the peaceful uses of nuclear technology and insures, through the application of safeguards inspections conducted by the International Atomic Energy Agency (IAEA), that those technologies are not being diverted toward the production of nuclear weapons. It is also the only multinational treaty that obligates the five nuclear weapons states that are party to the treaty (China, France, Great Britain, Russia, and the United States) to pursue nuclear disarmament measures. Though there have been many challenges over the years, most would agree that the treaty has largely been successful. However, many are concerned about the continued viability of the NPT. The perceived slow pace of nuclear disarmament, the interest by some countries to consider a weapons program while party to the treaty, and the funding and staffing issues at the IAEA, are all putting considerable strain on the treaty. This manuscript explores those issues and offers some possible solutions to ensure that the NPT will survive effectively for many years to come.

Nonproliferation and Threat Reduction Assistance: U.S. Programs in the Former Soviet Union

DTIC Science & Technology

2008-01-03

Technology Center ( ISTC ) in Moscow and its companion Science and Technology Center (STCU) in Kiev, Ukraine. In the FY2005 budget request, it combined...International Science and Technology Center ( ISTC ) in Moscow. Several other former Soviet states joined the center during the 1990s, and other nations, including...research funded by these centers. The Moscow Center funded nearly 1,700 projects that engaged about 41,000 scientists. In 2001, the ISTC in Moscow

Nonproliferation and Threat Reduction Assistance: U.S. Programs in the Former Soviet Union

DTIC Science & Technology

2007-11-28

former Soviet Union.67 The State Department also manages and funds the International Science and Technology Center ( ISTC ) in Moscow and its companion...late 1992, the United States, Japan, the European Union, and Russia established the International Science and Technology Center ( ISTC ) in Moscow...funded nearly 1,700 projects that engaged about 41,000 scientists. In 2001, the ISTC in Moscow supported more than 22,000 scientists with more than $29

Selective Activation of a Perforin-Granzyme B Fusion Protein Toxin by PSA as Therapy for Metastatic Prostate Cancer

DTIC Science & Technology

2016-10-01

Prostate Cancer PRINCIPAL INVESTIGATOR: Samuel Denmeade RECIPIENT: Johns Hopkins University Baltimore, MD 21218 REPORT DATE: October 2016 TYPE...PSA as Therapy for Metastatic Prostate Cancer 5b. GRANT NUMBER W81XWH-15-1-0382 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Samuel R Denmeade...cytotoxic agent that can selectively kill both proliferating and non-proliferating prostate cancer cells within a metastatic site without significant host

2013 Snapshot of NGSI Human Capital Development and Future Roadmap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scholz, Melissa A; Poe, Sarah M; Dewji, Shaheen A

2013-01-01

Since its creation in 2008, the Human Capital Development (HCD) subprogram of NNSA s Next Generation Safeguards Initiative (NGSI) has been striving to develop sustainable academic and technical programs that support the recruitment, education, training, and retention of the next generation of international safeguards professionals. This effort endeavors to develop additional human resources to equip a new cadre of safeguards and nonproliferation experts to meet the needs of both the United States and the International Atomic Energy Agency (IAEA) for decades to come, specifically in response to data that indicates that 82% of the 2009 safeguards experts at U.S. Laboratoriesmore » will have left the workforce within 15 years. This paper provides an update on the status of the program since its last presentation at the INMM Annual Meeting in 2010, including strengthened and integrated efforts in the areas of graduate and post-doctoral fellowships, young and mid-career professional support, additional short safeguards coursework, and expanded university engagement. In particular, the paper will cover the NGSI Human Capital Roadmap currently being developed in safeguards and nonproliferation education, training, and knowledge retention. The NGSI Human Capital Roadmap aims to provide additional data points and metrics on where the human capital demand lies, which disciplines and skill sets are needed in the field, and how NGSI HCD can best address these issues to meet future demand.« less

78 FR 9768 - Bureau of International Security and Nonproliferation Imposition of Nonproliferation Measures...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... technology controlled under multilateral control lists (Missile Technology Control Regime, Australia Group... or ballistic missile sytems. The latter category includes (a) items of the same kind as those on... potential of making a material contribution to WMD or cruise or ballistic missile systems, (b) items on U.S...

75 FR 28672 - Bureau of International Security and Nonproliferation; Lifting of Nonproliferation Measures...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-21

...: Effective Date: May 21, 2010. FOR FURTHER INFORMATION CONTACT: Pamela K. Durham, Office of Missile Threat... in the foreign policy or national security interests of the United States to remove the restrictions..., their sub-units and successors: 1. D. Mendeleyev University of Chemical Technology of Russia 2. Moscow...

Fukushima Daiichi: implications for carbon-free energy, nuclear nonproliferation, and community resilience.

PubMed

Hall, Howard L

2011-07-01

Implications of the nuclear power plant accidents at Fukushima Daiichi are explored in this commentary. In addition to questions of nuclear reactor regulatory standards, broader implications on noncarbon-emitting energy production, nuclear nonproliferation objectives, and community resilience and emergency response against catastrophic events are explored. Copyright © 2011 SETAC.

Multilateral Cooperation on Nonproliferation

DTIC Science & Technology

2012-10-01

Nathan E . Busch and Daniel H. Joyner, eds., Combating Weapons of Mass Destruction: The Future of International Nonproliferation Policy (Athens, GA...or the World Bank . These organizations receive contributions from member states but have their own...Opening Reception Jack’s Lounge , Portola Hotel Friday, March 30, 2010 Timeline Content Delivery 7:30-8:30 Breakfast and Registration Cottonwood

Emerging national space launch programs: Economics and safeguards

NASA Astrophysics Data System (ADS)

Chow, Brian G.

Most ballistic missile nonproliferation studies have focused on trends in the numbers and performance of missiles and the resulting security threats. This report concentrates on the economic viability of emerging national space launch programs and the prospects for imposing effective safeguards against the use of space launch technology for military missiles. For the convenience of discussion in this report, a reference to ballistic missiles hereafter means surface-to-surface guided ballistic missiles only. Space launch vehicles (SLV's) are surface-to-space ballistic missiles, and they will be referred to explicitly as 'space launch vehicles' or 'space launchers'. Surface-to-surface unguided ballistic missiles will be referred to as 'rockets.'

Workshop on nuclear power growth and nonproliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pilat, Joseph F

2010-01-01

It is widely viewed that an expansion of nuclear power would have positive energy, economic and environmental benefits for the world. However, there are concerns about the economic competitiveness, safety and proliferation and terrorism risks of nuclear power. The prospects for a dramatic growth in nuclear power will depend on the ability of governments and industry to address these concerns, including the effectiveness of, and the resources devoted to, plans to develop and implement technologies and approaches that strengthen nonproliferation, nuclear materials accountability and nuclear security. In his Prague speech, President Obama stated: 'we should build a new framework formore » civil nuclear cooperation, including an international fuel bank, so that countries can access peaceful power without increasing the risks of proliferation. That must be the right of every nation that renounces nuclear weapons, especially developing countries embarking on peaceful programs. And no approach will succeed if it's based on the denial of rights to nations that play by the rules. We must harness the power of nuclear energy on behalf of our efforts to combat climate change, and to advance peace opportunity for all people.' How can the President's vision, which will rekindle a vigorous public debate over the future of nuclear power and its relation to proliferation, be realized? What critical issues will frame the reemerging debate? What policies must be put into place to address these issues? Will US policy be marked more by continuity or change? To address these and other questions, the Los Alamos National Laboratory in cooperation with the Woodrow Wilson International Center for Scholars will host a workshop on the future of nuclear power and nonproliferation.« less

Nonproliferation and Threat Reduction Assistance: U.S. Programs in the Former Soviet Union

DTIC Science & Technology

2007-02-23

FY1996 and FY2002 in the former Soviet Union.67 The State Department also manages and funds the International Science and Technology Center ( ISTC ) in...Center ( ISTC ) in Moscow. Several other former Soviet states joined the center during the 1990s, and other nations, including Norway and South Korea...centers. The Moscow Center funded nearly 1,700 projects that engaged about 41,000 scientists. In 2001, the ISTC in Moscow supported more than 22,000

Environmental Measurements Laboratory fiscal year 1998: Accomplishments and technical activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson, M.D.

1999-01-01

The Environmental Measurements Laboratory (EML) is government-owned, government-operated, and programmatically under the DOE Office of Environmental Management. The Laboratory is administered by the Chicago Operations Office. EML provides program management, technical assistance and data quality assurance for measurements of radiation and radioactivity relating to environmental restoration, global nuclear nonproliferation, and other priority issues for the Department of Energy, as well as for other government, national, and international organizations. This report presents the technical activities and accomplishments of EML for Fiscal Year 1998.

Nuclear Nonproliferation: Concerns With U.S. Delays in Accepting Foreign Research Reactors’ Spent Fuel

DTIC Science & Technology

1994-03-01

transport or storage plans. The return of some of the spent fuel will also depend on the readiness of dry storage . One expert told us that...enriched uranium fuel (HEU), a material that can be used to make nuclear bombs, in civilian nuclear programs worldwide. Research reactors are of...address the environmental impact of transporting the fuel and storing it in both existing and new storage units, possibly by June 1995. Under the

Organizational Culture for Safety, Security, and Safeguards in New Nuclear Power Countries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kovacic, Donald N

2015-01-01

This chapter will contain the following sections: Existing international norms and standards for developing the infrastructure to support new nuclear power programs The role of organizational culture and how it supports the safe, secure, and peaceful application of nuclear power Identifying effective and efficient strategies for implementing safety, security and safeguards in nuclear operations Challenges identified in the implementation of safety, security and safeguards Potential areas for future collaboration between countries in order to support nonproliferation culture

China's Case Against the Nuclear Non-Proliferation Treaty: Rationality and Morality.

ERIC Educational Resources Information Center

Hunt, Geoffrey

1986-01-01

China and other major Third World nations have refused to sign the Nuclear Non-Proliferation Treaty (NPT). While this position appears morally unjustified and even irrational, their claim that the treaty is discriminatory merits serious attention. Only if certain aspects of this claim are accepted by the nuclear weapons signatories, does a moral…

NNSA Signs Memorandum with Kuwait to Increase Cooperation on Nuclear Safeguards and Nonproliferation

ScienceCinema

Thomas D'Agostino

2017-12-09

On June 23, 2010, the National Nuclear Security Administration (NNSA) signed a Memorandum of Cooperation on nuclear safeguards and other nonproliferation topics with the Kuwait National Nuclear Energy Committee (KNNEC). NNSA Administrator Thomas D'Agostino and KNNEC's Secretary General, Dr. Ahmad Bishara, signed the memorandum at a ceremony at U.S. Department of Energy headquarters in Washington.

Fostering Cooperation in Nonproliferation Activities

DTIC Science & Technology

2007-12-01

the Soviet Threat Reduction Act of 1991 was expanded and transformed, by sponsoring Senators Sam Nunn (D-GA) and Richard Lugar ( R -IN), into the...Bureau of Arms Control, U.S. State Department, Hearing before the Subcommittee on Terrorism and Nonproliferation, International Relations Committee...carrot-and-stick approach to gaining PSI support, Congressman Sherman indicated, later in the hearing , that participation in the PSI might affect

University of Texas Safeguards by Design Problem Statement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rauch, Eric Benton; Scherer, Carolynn P.; Ruggiero, Christy E.

This document describes the problem statement that students at the University of Texas will use for their senior level capstone design class. The purpose of this project is to introduce students to Safeguards by Design concepts as part of their capstone design course at the culmination of their degree program. This work is supported by Los Alamos National Laboratory with FY17 and FY18 programmatic funding from the U. S. Department of Energy’s (DOE) National Nuclear Security Administration (NNSA), through the Office of Defense Nuclear Nonproliferation (DNN), Office of International Nuclear Safeguards (INS), Next Generation Safeguards Initiative (NGSI), Human Resource Developmentmore » Program, Safeguards by Design Project.« less

Threat Control through Arms Control. Report to Congress 1994

DTIC Science & Technology

1994-07-13

reduction, chemical weapons’ elimination, or any of the other growing arms control and nonproliferation challenges America faces, ACDA is an essential...nuclear missile reduction, chemical weapons elimination, or any of. the other growing arms control and nonproliferation challenges America faces... challenging . Nonprolif eration agreements are our first line of defense against the creation of a far more unstable and hazardous world than we have ever

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walter, Andrew

National policymakers are currently considering a dilemma of critical importance to the continued security of the United States: how can U.S. nuclear weapons policies be leveraged to benefit U.S. nuclear nonproliferation goals in the near-term, without sacrificing U.S. national security? In its role supporting U.S. nuclear weapons policy, Sandia National Laboratories has a responsibility to provide objective technical advice to support policy deliberations on this question. However, to best fulfill this duty Sandia must have a broader understanding of the context of the problem. To help develop this understanding, this paper analyzes the two predominant analytical perspectives of international relationsmore » theory to explore their prescriptions for how nuclear weapons and nonproliferation policies interact. As lenses with which to view and make sense of the world, theories of international relations must play a crucial role in framing the trade-offs at the intersection of the nuclear weapons and nonproliferation policy domains. An analysis of what these theories suggest as courses of action to leverage nuclear weapons policies to benefit nonproliferation goals is then offered, with particular emphasis on where the policy prescriptions resulting from the respective theories align to offer near-term policy changes with broad theoretical support. These policy prescriptions are then compared to the 2001 Nuclear Posture Review to understand what the theories indicate policymakers may have gotten right in their dealing with the nuclear dilemma, and where they may have gone wrong. Finally, a brief international relations research agenda is proposed to help address the dilemma between nuclear deterrence and nuclear nonproliferation policies, with particular emphasis on how such an agenda can best support the needs of the policy community and a potential 'all things nuclear' policy deliberation and decision-support framework.« less

Nonproliferation Uncertainties, a Major Barrier to Used Nuclear Fuel Recycle in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Collins, Emory D; Ehinger, Michael H

2011-01-01

A study and comparison of the goals and understandings of nonproliferation authorities with those of used nuclear fuel (UNF) recycle advocates have uncovered (1) some of the basic reasons for the creation of uncertainties by each of the parties, (2) why these uncertainties have become a major barrier to a decision to recycle UNF components in the United States, and (3) what steps can be taken to clarify these uncertainties. Recent papers and viewpoints expressed by nonproliferation authorities and technical consultants were reviewed, summarized, and compared with results of recent fuel cycle systems analyses made at Oak Ridge National Laboratory.more » 1 Similarities and differences were identified, including both technical and policy factors. Nonproliferation authorities and a few UNF recycle advocates have recognized that the reprocessing technologies used for UNF component recycle do not offer significant nonproliferation differences; thus, the methods used can be chosen on some other basis, such as process efficiency, maturity, and/or economics. This paper reviews the safeguards implications beyond the simple assessment of UNF recycle technology selection. Differences in understanding that led to uncertainty barriers to UNF recycle include (1) the vulnerability of unseparated UNF, (2) the effects of time factors on production and accumulation of fissile plutonium isotopes and decay of the ?self-protecting radiation barrier,? (3) the chemistry of UNF components and relative ease of separation, and (4) the significant differences in commercialscale ?safeguards-by-design? UNF recycle facilities and smaller-scale covert operations. Application of safeguards-by-design and engineered safeguards can provide the defense-in-depth necessary for sufficient safeguards. Establishing these requirements for governing acceptable commercial UNF component recycle is essential.« less

Nuclear Security Applications of Antineutrino Detectors: Current Capabilities and Future Prospects

DOE PAGES

Bernstein, Adam; Baldwin, George; Boyer, Brian; ...

2010-12-10

Antineutrinos are electrically neutral, nearly massless fundamental particles produced in large numbers in the cores of nuclear reactors and in nuclear explosions. In the half century since their discovery, major advances in the understanding of their properties, and in detector technology, have opened the door to a new discipline—Applied Antineutrino Physics. Because antineutrinos are inextricably linked to the process of nuclear fission, there are many applications of interest in nuclear nonproliferation. This work presents a comprehensive survey of applied antineutrino physics relevant for nonproliferation, summarizes recent advances in the field, describes the overlap of this nascent discipline with other ongoingmore » fundamental and applied antineutrino research, and charts a course for research and development for future applications. It is intended as a resource for policymakers, researchers, and the wider nuclear nonproliferation community.« less

Nuclear security applications of antineutrino detectors : current capabilities and future prospects.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernstein, A.; Goodman, M.; Baldwin, G.

2010-12-10

Antineutrinos are electrically neutral, nearly massless fundamental particles produced in large numbers in the cores of nuclear reactors and in nuclear explosions. In the half century since their discovery, major advances in the understanding of their properties, and in detector technology, have opened the door to a new discipline - Applied Antineutrino Physics. Because antineutrinos are inextricably linked to the process of nuclear fission, there are many applications of interest in nuclear nonproliferation. This paper presents a comprehensive survey of applied antineutrino physics relevant for nonproliferation, summarizes recent advances in the field, describes the overlap of this nascent discipline withmore » other ongoing fundamental and applied antineutrino research, and charts a course for research and development for future applications. It is intended as a resource for policymakers, researchers, and the wider nuclear nonproliferation community.« less

Social Data Analysis by Non-Linear Imbedding

DTIC Science & Technology

2013-09-20

Fig. 1 shows this dimenion-reduced galaxy. This example is chosen to illustrate how our “ history independent” techniques can infer major historical...DISTRIBUTION A: Distribution approved for public release. 1989 1990 1991 Middle East 2 7 6 Weapon Nonproliferation 2 6 5 Anti- Apartheid & Human Rights...the Non-Proliferation of Nuclear Weapons) #3570 (Status of the International Convention on the Suppression and Punishment of the crime of Apartheid

Managing the Nuclear Fuel Cycle: Policy Implications of Expanding Global Access to Nuclear Power

DTIC Science & Technology

2007-11-01

critical aspect of the nuclear fuel cycle for the United States, where longstanding nonproliferation policy discouraged commercial nuclear fuel...perhaps the most critical question in this decade for strengthening the nuclear nonproliferation regime: how can access to sensitive fuel cycle...process can take advantage of the slight difference in atomic mass between 235U and 238U. The typical enrichment process requires about 10 lbs of uranium

Miscalculated Ambiguity: The Effects of US Nuclear Declaratory Policy on Deterrence and Nonproliferation

DTIC Science & Technology

2010-06-01

Business, Sports , Entertainment and Video News. http://edition.cnn.com/2010/ US /08/27/debt.security.mullen/index.html (accessed March 23, 2011). 70...sole-purpose policy would also vastly enhance US nonproliferation efforts. This policy would increase US legitimacy as the leader of the...March 29, 2011). 93 "Iran Ridicules Obama Nuclear Policy - USATODAY.com." News, Travel, Weather, Entertainment , Sports , Technology, U.S. & World

University-level Non-proliferation and Safeguards Education and Human Capital Development Activities at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bachner K. M.; Pepper, S.; Gomera, J.

BNL has offered Nuclear Nonproliferation, Safeguards and Security in the 21st Century,? referred to as NNSS, every year since 2009 for graduate students in technical and policy fields related to nuclear safeguards and nonproliferation. The course focuses on relevant policy issues, in addition to technical components, and is part of a larger NGSI short course initiative that includes separate courses that are delivered at three other national laboratories and NNSA headquarters. [SCHOLZ and ROSENTHAL] The course includes lectures from esteemed nonproliferation experts, tours of various BNL facilities and laboratories, and in-field and table-top exercises on both technical and policy subjects.more » Topics include the history of the Treaty on the Non-proliferation of Nuclear Weapons (NPT) and other relevant treaties, the history of and advances in international nuclear safeguards, current relevant political situations in countries such as Iran, Iraq, and the Democratic Peoples? Republic of Korea (DPRK), nuclear science and technology, instrumentation and techniques used for verification activities, and associated research and development. The students conduct a mock Design Information Verification (DIV) at BNL?s decommissioned Medical Research Reactor. The capstone of the course includes a series of student presentations in which students act as policy advisors and provide recommendations in response to scenarios involving a current nonproliferation related event that are prepared by the course organizers. ?The course is open to domestic and foreign students, and caters to students in, entering, or recently having completed graduate school. Interested students must complete an application and provide a resume and a statement describing their interest in the course. Eighteen to 22 students attend annually; 165 students have completed the course to date. A stipend helps to defray students? travel and subsistence expenses. In 2015, the course was shortened from three weeks to two weeks to streamline the material, standardize NGSI course length, and draw in a larger applicant pool. ?The international and interdisciplinary mix of students attending the course encourages discussions of the topics presented during the course. Information about the course is available at https://www.bnl.gov/nnsscourse/. While a complete analysis of course students has not been undertaken, BNL is aware of three individuals who worked at national laboratories after attending the NNSS course, one who worked at a national laboratory prior to attending NNSS, two who worked as federal employees after attending NNSS, three who were Nonproliferation Graduate Fellows before or after attending NNSS, and three who have participated in other NGSI activities.?Design Information Verification is an IAEA inspection activity that is implemented for the purpose of ensuring that the facility design is consistent with the declared use of a facility.« less

Atoms for peace and the nonproliferation treaty: unintended consequences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Streeper, Charles Blamires

2009-01-01

In April 2009, President Obama revived nonproliferation and arms control efforts with a speech calling for the worldwide abolition of nuclear weapons. His speech correctly acknowledged the threat of nuclear terrorism and the vulnerabilities of the related unsecure nuclear materials. Unfortunately, the president did not mention and has not mentioned in any speech the threat posed by at-risk radiological materials. Nonproliferation efforts have a well documented history of focus on special nuclear materials (fissionable weapons usable materials or SNM), and other key materials (chemical and biological) and technologies for a Weapon of Mass Destruction (WMD). Such intense focus on WMDmore » related materials/technologies is essential for international safety and security and merit continued attention and funding. However, the perception that radioactive sealed sources (sources) are of less concern than WMD is unfortunate. These perceptions are based solely on the potentially enormous and tragic consequences associated with their deliberate or accidental misuse and proliferation concerns. However, there is a documented history of overemphasis on the nuclear threat at the expense of ignoring the far more likely and also devastating chemical and biological threats. The radiological threat should not be minimized or excluded from policy discussions and decisions on these far ranging scopes of threat to the international community. Sources have a long history of use; and a wider distribution worldwide than fissile materials. Pair this with their broad ranges in isotopes/activities along with scant national and international attention and mechanisms for their safe and secure management and it is not difficult to envision a deadly threat. Arguments that minimize or divert attention away from sources may have the effect of distracting necessary policy attention on preventing/mitigating a radiological dispersal event. The terrorist attacks on 9/11 should be a clear reminder of the inherent danger of diminishing or dismissing lower-level threats in exchange for enhanced focus on high priority special nuclear materials with the basis for this emphasis being solely on the magnitude of the consequences of a single event. Mitigating all possible or likely terrorist attacks is impossible; however, weaponized sources, in the form of a radiological dispersal device, have been a declared target material of Al-Qaida. Eisenhower's Atoms for Peace initiative promoted the spread of the paradoxical beneficial yet destructive properties of the atom. Typically, the focus of nonproliferation efforts focuses on the fissile materials associated with Weapons of Mass Destruction, with less emphasis on radioactive materials that could be used for a Weapon of Mass Disruption. Most nonproliferation policy discussion involves securing or preventing the diversion of weapons grade fissile materials (uranium (U) with concentration of over 90% of the isotope {sup 235}U (HEU) and plutonium with more than 90% of the isotope {sup 239}Pu), with scant attention given to the threat posed by a prolific quantity of sources spread worldwide. Further acerbating the problem of inattention, it appears that the momentum of the continued evolution in the beneficial applications of sources will only increase in the near future. Several expert studies have demonstrated on the potentially devastating economic, psychological and public health impacts of terrorist use of a radiological dispersal or radiation emitting device (ROD/RED) in a metropolis. The development of such a weapon, from the acquisition of the radioactive material to the technical knowledge needed to fashion it into an ROD, is many orders of magnitude easier than diverting enough fissile material for and fabrication/acquisition of a nuclear weapon. Unlike nuclear weapons, worldwide, there are many well documented accounts of accidental and purposeful diversions of radioactive materials from regulatory control. As of the end of 2008, the International Atomic Energy Agency's (IAEA) Illicit Trafficking Database had logged 1562 incidents, of which only 18 include weapons grade nuclear materials. As much as 66% of the radioactive material involved in these incidents was not recovered. Since 2004, there has been a 75% increase in incidents of unrecoverable material, much of which is labeled dangerous with potential for deterministic health affects if misused. This makes clear that a black market of illicit trade in sources exists. The incidents reported to the IAEA's database rely only on voluntary state reporting; therefore, the number of lost or stolen sources is expected to be much higher.« less

Assessing the Institution of the Nuclear Nonproliferation Regime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toomey, Christopher

2010-05-14

The nuclear nonproliferation regime is facing a crisis of effectiveness. During the Cold War, the regime was relatively effective in stemming the proliferation of nuclear weapons and building an institutional structure that could, under certain conditions, ensure continued success. However, in the evolving global context, the traditional approaches are becoming less appropriate. Globalization has introduced new sets of stresses on the nonproliferation regime, such as the rise of non-state actors, broadening extensity and intensity of supply chains, and the multipolarization of power. This evolving global context demands an analytical and political flexibility in order to meet future threats. Current institutionalmore » capabilities established during the Cold War are now insufficient to meet the nonproliferation regime’s current and future needs. The research was based on information gathered through interviews and reviews of the relevant literature, and two dominant themes emerged. First, that human security should be integrated into the regime to account for the rise of non-state actors and networked violence. Second, confidence in the regime’s overall effectiveness has eroded at a time where verification-based confidence is becoming more essential. The research postulates that a critical analysis of the regime that fully utilizes institutional theory, with its focus on rules, normative structures, and procedures will be essential to adapting the regime to the current global context, building mechanisms for generating trust, creating better enforcement, and providing flexibility for the future.« less

INTEGRATION OF FACILITY MODELING CAPABILITIES FOR NUCLEAR NONPROLIFERATION ANALYSIS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gorensek, M.; Hamm, L.; Garcia, H.

2011-07-18

Developing automated methods for data collection and analysis that can facilitate nuclear nonproliferation assessment is an important research area with significant consequences for the effective global deployment of nuclear energy. Facility modeling that can integrate and interpret observations collected from monitored facilities in order to ascertain their functional details will be a critical element of these methods. Although improvements are continually sought, existing facility modeling tools can characterize all aspects of reactor operations and the majority of nuclear fuel cycle processing steps, and include algorithms for data processing and interpretation. Assessing nonproliferation status is challenging because observations can come frommore » many sources, including local and remote sensors that monitor facility operations, as well as open sources that provide specific business information about the monitored facilities, and can be of many different types. Although many current facility models are capable of analyzing large amounts of information, they have not been integrated in an analyst-friendly manner. This paper addresses some of these facility modeling capabilities and illustrates how they could be integrated and utilized for nonproliferation analysis. The inverse problem of inferring facility conditions based on collected observations is described, along with a proposed architecture and computer framework for utilizing facility modeling tools. After considering a representative sampling of key facility modeling capabilities, the proposed integration framework is illustrated with several examples.« less

Ecological Monitoring and Compliance Program 2006 Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

David C. Anderson; Paul D. Greger; Derek B. Hall

2007-03-01

The Ecological Monitoring and Compliance program (EMAC), funded through the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO), monitors the ecosystem of the Nevada Test Site (NTS) and ensures compliance with laws and regulations pertaining to NTS biota. This report summarizes the program's activities conducted by National Security Technologies LLC (NSTec) during the Calendar Year 2006. Program activities included: (a) biological surveys at proposed construction sites, (b) desert tortoise compliance, (c) ecosystem mapping and data management, (d) sensitive plant species monitoring, (e) sensitive and protected/regulated animal monitoring, (f) habitat monitoring, (g) habitat restoration monitoring, and (h)more » monitoring of the Nonproliferation Test and Evaluation Complex (NPTEC). Sensitive and protected/regulated species of the NTS include 44 plants, 1 mollusk, 2 reptiles, over 250 birds, and 26 mammals protected, managed, or considered sensitive as per state or federal regulations and natural resource agencies and organizations. The threatened desert tortoise (Gopherus agassizii) is the only species on the NTS protected under the Endangered Species Act. Biological surveys for the presence of sensitive and protected/regulated species and important biological resources on which they depend were conducted for 34 projects. A total of 342.1 hectares (ha) (845.37 acres [ac]) was surveyed for these projects. Sensitive and protected/regulated species and important biological resources found included: 2 inactive tortoise burrows, 2 western burrowing owls (Athene cunicularia hypugaea), several horses (Equus caballus), 2 active predator burrows, mature Joshua trees (Yucca brevifolia), yuccas and cacti; and also 1 bird nest (2 eggs), 1 barn owl (Tyto alba) and 2 great-horned owls (Bubo virginianus). NSTec provided a written summary report of all survey findings and mitigation recommendations, where applicable. All flagged burrows were avoided during construction activities. Twenty one of the 34 projects had sites within the distribution range of the threatened desert tortoise. NNSA/NSO must comply with the terms and conditions of a permit (called a Biological Opinion) from the U.S. Fish and Wildlife Service (FWS) when conducting work in tortoise habitat. No tortoises were found in or displaced from project areas. No desert tortoises were accidentally injured or killed, nor were any captured or displaced from project sites. One desert tortoise was accidentally killed along a paved road. One site specific re-vegetation plan was submitted this year as required by the desert tortoise habitat re-vegetation plan approved in 2004. This year a total of 1.89 ha (4.69 ac) of tortoise habitat was disturbed. Re-vegetation of habitat at the Bren Tower burn was completed in the spring of 2006. In the summer of 2006, NSTec scientists prepared a Biological Assessment of the security activities that were being conducted at the Device Assembly Facility (DAF). NNSA requested a Biological Opinion from FWS in late 2006. Ecosystem mapping and data management in 2006 focused primarily on two tasks: (a) converting hardcopies of about 17 reports (EMAC annual reports and selected topical reports from 1996 to 2003) into electronic versions (Portable Document Format [PDF] files) to facilitate electronic document exchange, rapid retrieval, duplication, and printing, and (b) conducting an annual vegetation survey to determine wildland fire hazards on the NTS. Copies of the PDF documents were sent to DOE's Office of Scientific and Technical Information website in Oak Ridge, Tennessee, and the DOE National Nuclear Security Administration Nevada Site Office (NNSA/NSO) Public Reading Facility.« less

Ecological Monitoring and Compliance Program 2006 Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

David C. Anderson; Paul D. Greger; Derek B. Hall

2007-03-01

The Ecological Monitoring and Compliance program (EMAC), funded through the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO), monitors the ecosystem of the Nevada Test Site (NTS) and ensures compliance with laws and regulations pertaining to NTS biota. This report summarizes the program's activities conducted by National Security Technologies LLC (NSTec) during the Calendar Year 2006. Program activities included: (a) biological surveys at proposed construction sites, (b) desert tortoise compliance, (c) ecosystem mapping and data management, (d) sensitive plant species monitoring, (e) sensitive and protected/regulated animal monitoring, (f) habitat monitoring, (g) habitat restoration monitoring, and (h)more » monitoring of the Nonproliferation Test and Evaluation Complex (NPTEC). Sensitive and protected/regulated species of the NTS include 44 plants, 1 mollusk, 2 reptiles, over 250 birds, and 26 mammals protected, managed, or considered sensitive as per state or federal regulations and natural resource agencies and organizations. The threatened desert tortoise (Gopherus agassizii) is the only species on the NTS protected under the Endangered Species Act. Biological surveys for the presence of sensitive and protected/regulated species and important biological resources on which they depend were conducted for 34 projects. A total of 342.1 hectares (ha) (845.37 acres [ac]) was surveyed for these projects. Sensitive and protected/regulated species and important biological resources found included: 2 inactive tortoise burrows, 2 western burrowing owls (Athene cunicularia hypugaea), several horses (Equus caballus), 2 active predator burrows, mature Joshua trees (Yucca brevifolia), yuccas and cacti; and also 1 bird nest (2 eggs), 1 barn owl (Tyto alba) and 2 great-horned owls (Bubo virginianus). NSTec provided a written summary report of all survey findings and mitigation recommendations, where applicable. All flagged burrows were avoided during construction activities. Twenty one of the 34 projects had sites within the distribution range of the threatened desert tortoise. NNSA/NSO must comply with the terms and conditions of a permit (called a Biological Opinion) from the U.S. Fish and Wildlife Service (FWS) when conducting work in tortoise habitat. No tortoises were found in or displaced from project areas. No desert tortoises were accidentally injured or killed, nor were any captured or displaced from project sites. One desert tortoise was accidentally killed along a paved road. One site specific revegetation plan was submitted this year as required by the desert tortoise habitat revegetation plan approved in 2004. This year a total of 1.89 ha (4.69 ac) of tortoise habitat was disturbed. Revegetation of habitat at the Bren Tower burn was completed in the spring of 2006. In the summer of 2006, NSTec scientists prepared a Biological Assessment of the security activities that were being conducted at the Device Assembly Facility (DAF). NNSA requested a Biological Opinion from FWS in late 2006. Ecosystem mapping and data management in 2006 focused primarily on two tasks: (a) converting hardcopies of about 17 reports (EMAC annual reports and selected topical reports from 1996 to 2003) into electronic versions (Portable Document Format [PDF] files) to facilitate electronic document exchange, rapid retrieval, duplication, and printing, and (b) conducting an annual vegetation survey to determine wildland fire hazards on the NTS.« less

Micropyrolyzer for chemical analysis of liquid and solid samples

DOEpatents

Mowry, Curtis D.; Morgan, Catherine H.; Manginell, Ronald P.; Frye-Mason, Gregory C.

2006-07-18

A micropyrolyzer has applications to pyrolysis, heated chemistry, and thermal desorption from liquid or solid samples. The micropyrolyzer can be fabricated from semiconductor materials and metals using standard integrated circuit technologies. The micropyrolyzer enables very small volume samples of less than 3 microliters and high sample heating rates of greater than 20.degree. C. per millisecond. A portable analyzer for the field analysis of liquid and solid samples can be realized when the micropyrolyzer is combined with a chemical preconcentrator, chemical separator, and chemical detector. Such a portable analyzer can be used in a variety of government and industrial applications, such as non-proliferation monitoring, chemical and biological warfare detection, industrial process control, water and air quality monitoring, and industrial hygiene.

Nuclear weapons modernizations

NASA Astrophysics Data System (ADS)

Kristensen, Hans M.

2014-05-01

This article reviews the nuclear weapons modernization programs underway in the world's nine nuclear weapons states. It concludes that despite significant reductions in overall weapons inventories since the end of the Cold War, the pace of reductions is slowing - four of the nuclear weapons states are even increasing their arsenals, and all the nuclear weapons states are busy modernizing their remaining arsenals in what appears to be a dynamic and counterproductive nuclear competition. The author questions whether perpetual modernization combined with no specific plan for the elimination of nuclear weapons is consistent with the nuclear Non-Proliferation Treaty and concludes that new limits on nuclear modernizations are needed.

New Brunswick Laboratory: Progress report, October 1993 through September 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The mission of the New Brunswick Laboratory of the US Department of Energy (DOE) is to serve as the National Certifying Authority for nuclear reference materials and to provide an independent Federal technical staff and laboratory resource performing nuclear material measurement, safeguards and non-proliferation functions in support of multiple program sponsors. During FY 94 New Brunswick Laboratory (NBL) completed development of a Strategic Plan which will aid in better defining performance oriented laboratory goals and objectives in each functional area consistent with the changing needs of the global nuclear community. This annual report describes accomplishments achieved in carrying out NBL`smore » assigned missions. Details of completed projects are reported in separate topical reports or as open-literature publications. Programs discussed here are: (1) safeguards assistance; (2) reference materials program; (3) measurement evaluation; (4) measurement services; and (5) measurement development.« less

JAEA's actions and contributions to the strengthening of nuclear non-proliferation

NASA Astrophysics Data System (ADS)

Suda, Kazunori; Suzuki, Mitsutoshi; Michiji, Toshiro

2012-06-01

Japan, a non-nuclear weapons state, has established a commercial nuclear fuel cycle including LWRs, and now is developing a fast neutron reactor fuel cycle as part of the next generation nuclear energy system, with commercial operation targeted for 2050. Japan Atomic Energy Agency (JAEA) is the independent administrative agency for conducting comprehensive nuclear R&D in Japan after the merger of Japan Atomic Energy Research Institute (JAERI) and Japan Nuclear Cycle Development Institute (JNC). JAEA and its predecessors have extensive experience in R&D, facility operations, and safeguards development and implementation for new types of nuclear facilities for the peaceful use of nuclear energy. As the operator of various nuclear fuel cycle facilities and numerous nuclear materials, JAEA makes international contributions to strengthen nuclear non-proliferation. This paper provides an overview of JAEA's development of nuclear non-proliferation and safeguards technologies, including remote monitoring of nuclear facilities, environmental sample analysis methods and new efforts since the 2010 Nuclear Security Summit in Washington D.C.

SAVANNAH RIVER SITE ENVIRONMENTAL REPORT FOR 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mamatey, A.; Dunaway-Ackerman, J.

2011-08-16

This report was prepared in accordance with U.S. Department of Energy (DOE) Order 231.1A, 'Environment, Safety and Health Reporting,' to present summary environmental data for the purpose of: (a) characterizing site's environmental management performance; (b) summarizing environmental occurrences and responses reported during the calendar year; (c) describing compliance status with respect to environmental standards and requirements; and (d) highlighting significant site programs and efforts. This report is the principal document that demonstrates compliance with the requirements of DOE Order 5400.5, 'Radiation Protection of the Public and the Environment,' and is a key component of DOE's effort to keep the publicmore » informed of environmental conditions at Savannah River Site (SRS). SRS has four primary missions: (1) Environmental Management - Cleaning up the legacy of the Cold War efforts and preparing decommissioned facilities and areas for long-term stewardship; (2) Nuclear Weapons Stockpile Support - Meeting the needs of the U.S. nuclear weapons stockpile through the tritium programs of the National Nuclear Security Administration (NNSA); (3) Nuclear Nonproliferation Support - Meeting the needs of the NNSA's nuclear nonproliferation programs by safely storing and dispositioning excess special nuclear materials; and (4) Research and Development - Supporting the application of science by the Savannah River National Laboratory (SRNL) to meet the needs of SRS, the DOE complex, and other federal agencies During 2010, SRS worked to fulfill these missions and position the site for future operations. SRS continued to work with the South Carolina Department of Health and Environmental Control (SCDHEC), the Environmental Protection Agency (EPA), and the Nuclear Regulatory Commission to find and implement solutions and schedules for waste management and disposition. As part of its mission to clean up the Cold War legacy, SRS will continue to address the highest-risk waste management issues by safely storing and preparing liquid waste and nuclear materials for disposition, and by safely stabilizing any tank waste residues that remain on site.« less

Monitoring and verification R&D

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pilat, Joseph F; Budlong - Sylvester, Kory W; Fearey, Bryan L

2011-01-01

The 2010 Nuclear Posture Review (NPR) report outlined the Administration's approach to promoting the agenda put forward by President Obama in Prague on April 5, 2009. The NPR calls for a national monitoring and verification R&D program to meet future challenges arising from the Administration's nonproliferation, arms control and disarmament agenda. Verification of a follow-on to New START could have to address warheads and possibly components along with delivery capabilities. Deeper cuts and disarmament would need to address all of these elements along with nuclear weapon testing, nuclear material and weapon production facilities, virtual capabilities from old weapon and existingmore » energy programs and undeclared capabilities. We only know how to address some elements of these challenges today, and the requirements may be more rigorous in the context of deeper cuts as well as disarmament. Moreover, there is a critical need for multiple options to sensitive problems and to address other challenges. There will be other verification challenges in a world of deeper cuts and disarmament, some of which we are already facing. At some point, if the reductions process is progressing, uncertainties about past nuclear materials and weapons production will have to be addressed. IAEA safeguards will need to continue to evolve to meet current and future challenges, and to take advantage of new technologies and approaches. Transparency/verification of nuclear and dual-use exports will also have to be addressed, and there will be a need to make nonproliferation measures more watertight and transparent. In this context, and recognizing we will face all of these challenges even if disarmament is not achieved, this paper will explore possible agreements and arrangements; verification challenges; gaps in monitoring and verification technologies and approaches; and the R&D required to address these gaps and other monitoring and verification challenges.« less

Laboratory Directed Research and Development Program FY2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

none, none

2012-04-27

Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2011 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). Going forward in FY 2012, the LDRD program also supports themore » Goals codified in the new DOE Strategic Plan of May, 2011. The LDRD program also supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Brief summares of projects and accomplishments for the period for each division are included.« less

Global biosurveillance: enabling science and technology. Workshop background and motivation: international scientific engagement for global security

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cui, Helen H

2011-01-18

Through discussion the conference aims to: (1) Identify core components of a comprehensive global biosurveillance capability; (2) Determine the scientific and technical bases to support such a program; (3) Explore the improvement in biosurveillance to enhance regional and global disease outbreak prediction; (4) Recommend an engagement approach to establishing an effective international community and regional or global network; (5) Propose implementation strategies and the measures of effectiveness; and (6) Identify the challenges that must be overcome in the next 3-5 years in order to establish an initial global biosurveillance capability that will have significant positive impact on BioNP as wellmore » as public health and/or agriculture. There is also a look back at the First Biothreat Nonproliferation Conference from December 2007. Whereas the first conference was an opportunity for problem solving to enhance and identify new paradigms for biothreat nonproliferation, this conference is moving towards integrated comprehensive global biosurveillance. Main reasons for global biosurveillance are: (1) Rapid assessment of unusual disease outbreak; (2) Early warning of emerging, re-emerging and engineered biothreat enabling reduced morbidity and mortality; (3) Enhanced crop and livestock management; (4) Increase understanding of host-pathogen interactions and epidemiology; (5) Enhanced international transparency for infectious disease research supporting BWC goals; and (6) Greater sharing of technology and knowledge to improve global health.« less

Use of open source information and commercial satellite imagery for nuclear nonproliferation regime compliance verification by a community of academics

NASA Astrophysics Data System (ADS)

Solodov, Alexander

The proliferation of nuclear weapons is a great threat to world peace and stability. The question of strengthening the nonproliferation regime has been open for a long period of time. In 1997 the International Atomic Energy Agency (IAEA) Board of Governors (BOG) adopted the Additional Safeguards Protocol. The purpose of the protocol is to enhance the IAEA's ability to detect undeclared production of fissile materials in member states. However, the IAEA does not always have sufficient human and financial resources to accomplish this task. Developed here is a concept for making use of human and technical resources available in academia that could be used to enhance the IAEA's mission. The objective of this research was to study the feasibility of an academic community using commercially or publicly available sources of information and products for the purpose of detecting covert facilities and activities intended for the unlawful acquisition of fissile materials or production of nuclear weapons. In this study, the availability and use of commercial satellite imagery systems, commercial computer codes for satellite imagery analysis, Comprehensive Test Ban Treaty (CTBT) verification International Monitoring System (IMS), publicly available information sources such as watchdog groups and press reports, and Customs Services information were explored. A system for integrating these data sources to form conclusions was also developed. The results proved that publicly and commercially available sources of information and data analysis can be a powerful tool in tracking violations in the international nuclear nonproliferation regime and a framework for implementing these tools in academic community was developed. As a result of this study a formation of an International Nonproliferation Monitoring Academic Community (INMAC) is proposed. This would be an independent organization consisting of academics (faculty, staff and students) from both nuclear weapon states (NWS) and non-nuclear weapon states (NNWS). This community analyzes all types of unclassified publicly and commercially available information to aid in detection of violations of the non-proliferation regime. INMAC shares all of this information with the IAEA and the public. Since INMAC is composed solely by members of the academic community, this organization would not demonstrate any biases in its investigations or reporting.

Nuclear weapons modernizations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kristensen, Hans M.

This article reviews the nuclear weapons modernization programs underway in the world's nine nuclear weapons states. It concludes that despite significant reductions in overall weapons inventories since the end of the Cold War, the pace of reductions is slowing - four of the nuclear weapons states are even increasing their arsenals, and all the nuclear weapons states are busy modernizing their remaining arsenals in what appears to be a dynamic and counterproductive nuclear competition. The author questions whether perpetual modernization combined with no specific plan for the elimination of nuclear weapons is consistent with the nuclear Non-Proliferation Treaty and concludesmore » that new limits on nuclear modernizations are needed.« less

Laboratory directed research and development annual report 2004.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2004. In addition to a programmatic and financial overview, the report includes progress reports from 352 individual R and D projects in 15 categories. The 15 categories are: (1) Advanced Concepts; (2) Advanced Manufacturing; (3) Biotechnology; (4) Chemical and Earth Sciences; (5) Computational and Information Sciences; (6) Differentiating Technologies; (7) Electronics and Photonics; (8) Emerging Threats; (9) Energy and Critical Infrastructures; (10) Engineering Sciences; (11) Grand Challenges; (12) Materials Science and Technology; (13) Nonproliferation and Materials Control; (14) Pulsed Power and High Energy Densitymore » Sciences; and (15) Corporate Objectives.« less

Materials @ LANL: Solutions for National Security Challenges

NASA Astrophysics Data System (ADS)

Teter, David

2012-10-01

Materials science activities impact many programmatic missions at LANL including nuclear weapons, nuclear energy, renewable energy, global security and nonproliferation. An overview of the LANL materials science strategy and examples of materials science programs will be presented. Major materials leadership areas are in materials dynamics, actinides and correlated electron materials, materials in radiation extremes, energetic materials, integrated nanomaterials and complex functional materials. Los Alamos is also planning a large-scale, signature science facility called MaRIE (Matter Radiation Interactions in Extremes) to address in-situ characterization of materials in dynamic and radiation environments using multiple high energy probes. An overview of this facility will also be presented.

Security implications of the proliferation of weapons of mass destruction in the Middle East. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hajjar, S.G.

1998-12-17

The author argues that the Arab-Israeli conflict, the Iran-Iraq rivalry, and the lack of progress in the peace process are strong incentives for nations in the region to acquire weapons of mass destruction (WMD). He documents Israeli, Iranian, and Arab WMD programs and capabilities, referencing use of WMD in the region. He discusses the reasons why the major regional powers seek WMD capabilities and examines the nature of the proliferation dynamic as well as nonproliferation and counterproliferation approaches applicable to the region. The author offers several recommendations designed to strengthen these efforts and deal more effectively with causes of proliferation.

The NPR, NPT and the prospects for disarmament

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pilat, Joseph F

2010-10-04

In Prague's Hradcany Square on April 5, 2009, President Barack Obama offered a bold vision of the nuclear future that encompasses both reducing nuclear dangers and pursuing the goal of a world without nuclear weapons while maintaining, as long as nuclear weapons remain, a safe secure, and effective arsenal, to deter potential adversaries and to assure U.S. allies and other security partners that they can count on America's security commitments. The agenda put forward in Prague involves the full range of issues from deterrence to nonproliferation and disarmament. The 2010 Nuclear Posture Review (NPR) report, reflecting the twin objectives ofmore » the Prague speech, for the first time places the United States effort to lead expanded international efforts to rebuild and strengthen the global nuclear nonproliferation regime at the top the U.S. nuclear agenda. This attention underscores the fact that the top priority of the United States is to discourage additional states from acquiring nuclear weapon capabilities and to stop terrorist groups from acquiring weapon-usable nuclear materials. It also reinforced the view that positively influencing the 2010 Review Conference (RevCon) of the Parties to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) was a key objective of the Obama Administration. The NPR developed both the vision and the policy, but details of implementation will need to be developed and better understood. This paper will address the Nuclear Posture Review and its implementation, as well as it's relation to, and impact on, the NPT RevCon and the long term prospects for nonproliferation and disarmament.« less

Nuclear threat on the Korean peninsula: The present and the future. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, S.

1994-04-01

Forty years after they were divided by the Cold War, South and North Korea are closer to reunification than ever before. However, North Korea's nuclear weapons program might cause South Koreans to be much less sure about reunification. Today the Cold War is over, but the Korean peninsula is still divided into two Koreas despite the new era of reconciliation. Since December 1991 when a non-aggression pact was signed barring nuclear weapons, North Korea has pursued its nuclear weapon development. In March 1993, North Korea declared its intention to withdraw from the Nuclear Non-Proliferation Treaty, and has been refusing amore » full inspection of its nuclear program. North Korea's nuclear issue is an international issue today. This paper discusses 'what threat we have today' and 'what should be done in the future.'.« less

The Future of Nonproliferation in a Changed and Changing Environment: A Workshop Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dreicer, M.

2016-08-30

The Center for Global Security Research and Global Security Principal Directorate at Lawrence Livermore National Laboratory convened a workshop in July 2016 to consider “The Future of Nonproliferation in a Changed and Changing Security Environment.” We took a broad view of nonproliferation, encompassing not just the treaty regime but also arms control, threat reduction, counter-­proliferation, and countering nuclear terrorism. We gathered a group of approximately 60 experts from the technical, academic, political, defense and think tank communities and asked them what—and how much—can reasonably be accomplished in each of these areas in the 5 to 10 years ahead. Discussion wasmore » on a not-­for-­attribution basis. This document provides a summary of key insights and lessons learned, and is provided to help stimulate broader public discussion of these issues. It is a collection of ideas as informally discussed and debated among a group of experts. The ideas reported here are the personal views of individual experts and should not be attributed to Lawrence Livermore National Laboratory.« less

National Center for Nuclear Security: The Nuclear Forensics Project (F2012)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klingensmith, A. L.

These presentation visuals introduce the National Center for Nuclear Security. Its chartered mission is to enhance the Nation’s verification and detection capabilities in support of nuclear arms control and nonproliferation through R&D activities at the NNSS. It has three focus areas: Treaty Verification Technologies, Nonproliferation Technologies, and Technical Nuclear Forensics. The objectives of nuclear forensics are to reduce uncertainty in the nuclear forensics process & improve the scientific defensibility of nuclear forensics conclusions when applied to nearsurface nuclear detonations. Research is in four key areas: Nuclear Physics, Debris collection and analysis, Prompt diagnostics, and Radiochemistry.

Leo Szilard Lectureship Award: Science Matters - Technical Dimensions of Arms Control and Non-Proliferation Agreements

NASA Astrophysics Data System (ADS)

Timbie, James

2017-01-01

Agreements to reduce nuclear arms and prevent proliferation of nuclear weapons are technical as well as political documents. They must be both technically sound and politically acceptable. This presentation illustrates technical aspects of arms control and non-proliferation agreements, with examples from SALT I, INF, the HEU Agreement, START, and the Iran nuclear negotiations, drawing on 44 years of personal experience in the negotiation of these agreements. The lecture is designed to convey an appreciation of the role that individuals with technical training can play in diplomatic efforts to reduce nuclear forces and prevent nuclear proliferation.

Nonproliferation Challenges in Space Defense Technology - PANEL

NASA Technical Reports Server (NTRS)

Houts, Michael G.

2016-01-01

The use of highly enriched uranium (HEU) almost always "helps" space fission systems. Nuclear Thermal Propulsion (NTP) and high power fission electric systems appear able to use < 20% enriched uranium with minimal / acceptable performance impacts. However, lower power, "entry level" systems may be needed for space fission technology to be developed and utilized. Low power (i.e. approx.1 kWe) fission systems may have an unacceptable performance penalty if LEU is used instead of HEU. Are there Ways to Support Non-Proliferation Objectives While Simultaneously Helping Enable the Development and Utilization of Modern Space Fission Power and Propulsion Systems?

The doctrine of the nuclear-weapon states and the future of non-proliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Panofsky, W.K.H.; Bunn, G.

Less than a year remains before the critical conference in April 1995 to review and extend the nuclear Non-Proliferation Treaty (NPT), the main international barrier to the proliferation of nuclear weapons. This is a critical moment for the United States. With the end of the Cold War, the likelihood of nuclear war with the states of the former Soviet Union has been radically reduced, but there is greatly increased concern over the potential threats from states or sub-state groups seeking to develop or acquire nuclear weapons and other weapons of mass destruction.

A Visual Analytics Approach to Structured Data Analysis to Enhance Nonproliferation and Arms Control Verification Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gillen, David S.

Analysis activities for Nonproliferation and Arms Control verification require the use of many types of data. Tabular structured data, such as Excel spreadsheets and relational databases, have traditionally been used for data mining activities, where specific queries are issued against data to look for matching results. The application of visual analytics tools to structured data enables further exploration of datasets to promote discovery of previously unknown results. This paper discusses the application of a specific visual analytics tool to datasets related to the field of Arms Control and Nonproliferation to promote the use of visual analytics more broadly in thismore » domain. Visual analytics focuses on analytical reasoning facilitated by interactive visual interfaces (Wong and Thomas 2004). It promotes exploratory analysis of data, and complements data mining technologies where known patterns can be mined for. Also with a human in the loop, they can bring in domain knowledge and subject matter expertise. Visual analytics has not widely been applied to this domain. In this paper, we will focus on one type of data: structured data, and show the results of applying a specific visual analytics tool to answer questions in the Arms Control and Nonproliferation domain. We chose to use the T.Rex tool, a visual analytics tool developed at PNNL, which uses a variety of visual exploration patterns to discover relationships in structured datasets, including a facet view, graph view, matrix view, and timeline view. The facet view enables discovery of relationships between categorical information, such as countries and locations. The graph tool visualizes node-link relationship patterns, such as the flow of materials being shipped between parties. The matrix visualization shows highly correlated categories of information. The timeline view shows temporal patterns in data. In this paper, we will use T.Rex with two different datasets to demonstrate how interactive exploration of the data can aid an analyst with arms control and nonproliferation verification activities. Using a dataset from PIERS (PIERS 2014), we will show how container shipment imports and exports can aid an analyst in understanding the shipping patterns between two countries. We will also use T.Rex to examine a collection of research publications from the IAEA International Nuclear Information System (IAEA 2014) to discover collaborations of concern. We hope this paper will encourage the use of visual analytics structured data analytics in the field of nonproliferation and arms control verification. Our paper outlines some of the challenges that exist before broad adoption of these kinds of tools can occur and offers next steps to overcome these challenges.« less

Bayesian Model Development for Analysis of Open Source Information to Support the Assessment of Nuclear Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gastelum, Zoe N.; Whitney, Paul D.; White, Amanda M.

2013-07-15

Pacific Northwest National Laboratory has spent several years researching, developing, and validating large Bayesian network models to support integration of open source data sets for nuclear proliferation research. Our current work focuses on generating a set of interrelated models for multi-source assessment of nuclear programs, as opposed to a single comprehensive model. By using this approach, we can break down the models to cover logical sub-problems that can utilize different expertise and data sources. This approach allows researchers to utilize the models individually or in combination to detect and characterize a nuclear program and identify data gaps. The models operatemore » at various levels of granularity, covering a combination of state-level assessments with more detailed models of site or facility characteristics. This paper will describe the current open source-driven, nuclear nonproliferation models under development, the pros and cons of the analytical approach, and areas for additional research.« less

Nevada National Security Site-Directed Research and Development FY 2011 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howard Bender, comp.

2012-04-25

This fiscal year 2011 annual report of the Site-Directed Research and Development program, the 10th anniversary edition, recognizes a full decade of innovative R&D accomplishments in support of the Nevada National Security Site (NNSS). Last year the NNSS itself was renamed to reflect a diversifying mission, and our R&D program has contributed significantly to shape emerging missions that will continue to evolve. New initiatives in stockpile stewardship science, nonproliferation, and treaty verification and monitoring have had substantial successes in FY 2011, and many more accomplishments are expected. SDRD is the cornerstone on which many of these initiatives rest. Historically supportingmore » our main focus areas, SDRD is also building a solid foundation for new, and non-traditional, emerging national security missions. The program continues its charter to advance science and technology for a broad base of agencies including the U.S. Department of Energy (DOE), U.S. Department of Defense (DoD), U.S. Department of Homeland Security (DHS), and many others.« less

User manual for the NTS ground motion data base retrieval program: ntsgm

DOE Office of Scientific and Technical Information (OSTI.GOV)

App, F.N.; Tunnell, T.W.

1994-05-01

The NTS (Nevada Test Site) Ground Motion Data Base is composed of strong motion data recorded during the normal execution of the US underground test program. It contains surface, subsurface, and structure motion data as digitized waveforms. Currently the data base contains information from 148 underground explosions. This represents about 4,200 measurements and nearly 12,000 individual digitized waveforms. Most of the data was acquired by Los Alamos National Laboratory (LANL) in connection with LANL sponsored underground tests. Some was acquired by Los Alamos on tests conducted by the Defense Nuclear Agency (DNA) and Lawrence Livermore National Laboratory (LLNL), and theremore » are some measurements that were acquired by the other test sponsors on their events and provided for inclusion in this data base. Data acquisition, creation of the data base, and development of the data base retrieval program (ntsgm) are the result of work in support of the Los Alamos Field Test Office and the Office of Nonproliferation and Arms Control.« less

IMPACT OF THE U.S. SUPPORT PROGRAM SAFEGUARDS INTERNSHIP PROGRAM.

DOE Office of Scientific and Technical Information (OSTI.GOV)

PEPPER, S.; OSIECKI, C.

2006-07-16

The U.S. Support Program began funding an internship program in the IAEA Department of Safeguards in 2002. Since that time, 39 U.S. citizens and permanent residents have been placed in one-year, paid internships with the IAEA. The management of the internship program was originally the responsibility of the International Safeguards Project Office but was transferred to the Office of Educational Programs at Brookhaven National Laboratory in 2004. Feedback on the internship program from the U.S. government and the IAEA has been positive. The interns have completed basic yet essential work for the Department of Safeguards and freed IAEA staff membersmore » to perform more complex tasks. The cost of an intern is low relative to other forms of human resources support. After the conclusion of their assignments, many of the interns go on to work for the U.S. government, the national laboratories, or companies in international safeguards and nonproliferation. This paper will discuss the work done by the interns for the IAEA, factors influencing the success of the internship program, and the effects the program has had on the careers of interns, in preparing the next generation to work in the nuclear industry, participation in INMM activities, and recruitment for U.S. citizens for safeguards positions.« less

Origin and function of myofibroblasts in kidney fibrosis.

PubMed

LeBleu, Valerie S; Taduri, Gangadhar; O'Connell, Joyce; Teng, Yingqi; Cooke, Vesselina G; Woda, Craig; Sugimoto, Hikaru; Kalluri, Raghu

2013-08-01

Myofibroblasts are associated with organ fibrosis, but their precise origin and functional role remain unknown. We used multiple genetically engineered mice to track, fate map and ablate cells to determine the source and function of myofibroblasts in kidney fibrosis. Through this comprehensive analysis, we identified that the total pool of myofibroblasts is split, with 50% arising from local resident fibroblasts through proliferation. The nonproliferating myofibroblasts derive through differentiation from bone marrow (35%), the endothelial-to-mesenchymal transition program (10%) and the epithelial-to-mesenchymal transition program (5%). Specific deletion of Tgfbr2 in α-smooth muscle actin (αSMA)(+) cells revealed the importance of this pathway in the recruitment of myofibroblasts through differentiation. Using genetic mouse models and a fate-mapping strategy, we determined that vascular pericytes probably do not contribute to the emergence of myofibroblasts or fibrosis. Our data suggest that targeting diverse pathways is required to substantially inhibit the composite accumulation of myofibroblasts in kidney fibrosis.

Origin and Function of Myofibroblasts in Kidney Fibrosis

PubMed Central

LeBleu, Valerie S.; Taduri, Gangadhar; O’Connell, Joyce; Teng, Yingqi; Cooke, Vesselina G.; Woda, Craig; Sugimoto, Hikaru; Kalluri, Raghu

2014-01-01

Myofibroblasts are associated with organ fibrosis but their precise origin and functional role remain unknown. We employed multiple genetically engineered mice to track, fate-map and ablate cells to determine the source and function of myofibroblasts in kidney fibrosis. Such comprehensive analysis identified that the total pool of myofibroblasts is split, with 50% arising from local resident fibroblasts via proliferation. The non-proliferating myofibroblasts derive via differentiation from bone marrow (35%), endothelial to mesenchymal transition (EndMT) program (10%) and epithelial to mesenchymal transition (EMT) program (5%). Specific deletion of Tgfbr2 in αSMA+ cells revealed the importance of this pathway in recruitment of myofibroblasts via differentiation. Using genetic mouse models and fate-mapping strategy we determined that vascular pericytes likely do not contribute to the emergence of myofibroblasts or fibrosis. This study suggests that targeting diverse pathways is required to significantly inhibit composite accumulation of myofibroblasts in kidney fibrosis. PMID:23817022

Nuclear energy related capabilities at Sandia National Laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pickering, Susan Y.

2014-02-01

Sandia National Laboratories' technology solutions are depended on to solve national and global threats to peace and freedom. Through science and technology, people, infrastructure, and partnerships, part of Sandia's mission is to meet the national needs in the areas of energy, climate and infrastructure security. Within this mission to ensure clean, abundant, and affordable energy and water is the Nuclear Energy and Fuel Cycle Programs. The Nuclear Energy and Fuel Cycle Programs have a broad range of capabilities, with both physical facilities and intellectual expertise. These resources are brought to bear upon the key scientific and engineering challenges facing themore » nation and can be made available to address the research needs of others. Sandia can support the safe, secure, reliable, and sustainable use of nuclear power worldwide by incorporating state-of-the-art technologies in safety, security, nonproliferation, transportation, modeling, repository science, and system demonstrations.« less

Production of an English/Russian glossary of terminology for nuclear materials control and accounting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schachowskoj, S.; Smith, H.A. Jr.

The program plans for Former Soviet Union National Nuclear Materials Control and Accounting (MC and A) Systems Enhancements call for the development of an English/Russian Glossary of MC and A terminology. This glossary was envisioned as an outgrowth of the many interactions, training sessions, and other talking and writing exercises that would transpire in the course of carrying out these programs. This report summarizes the status of the production of this glossary, the most recent copy of which is attached to this report. The glossary contains over 950 terms and acronyms associated with nuclear material control and accounting for safeguardsmore » and nonproliferation. This document is organized as follows: English/Russian glossary of terms and acronyms; Russian/English glossary of terms and acronyms; English/Russian glossary of acronyms; and Russian/English glossary of acronyms.« less

The Power of Integrators, Financiers, and Insurers to Reduce Proliferation Risks: Nuclear Dual-Use Goods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weise, Rachel A.; Hund, Gretchen

2015-05-01

Globalization of manufacturing supply chains has changed the nature of nuclear proliferation. Before 1991, nonproliferation efforts focused almost exclusively on limiting the spread of materials and equipment specifically designed for nuclear use -- reactors, centrifuges, and fissile material. Dual-use items, those items with both nuclear and non-nuclear applications, were not closely scrutinized or controlled. However, in 1991 the international community discovered that Iraq had developed a fairly sophisticated nuclear weapons program by importing dual-use items; this discovery spurred the international community to increase controls on dual-use technologies. Despite these international efforts, dual-use items are still a challenge for those seekingmore » to limit proliferation.« less

Training in Tbilisi nuclear facility provides new sampling perspectives for IAEA inspectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brim, Cornelia P.

2016-06-08

Office of Nonproliferation and Arms Control- (NPAC-) sponsored training in a “cold” nuclear facility in Tbilisi, Georgia provides International Atomic Energy Agency (IAEA) inspectors with a new perspective on environmental sampling strategies. Sponsored by the Nuclear Safeguards program under the NPAC, Pacific Northwest National Laboratory (PNNL) experts have been conducting an annual weeklong class for IAEA inspectors in a closed nuclear facility since 2011. The Andronikashvili Institute of Physics and the Republic of Georgia collaborate with PNNL to provide the training, and the U.S. Department of State, the U.S. Embassy in Tbilisi and the U.S. Mission to International Organizations inmore » Vienna provide logistical support.« less

DOE Non-Proliferation Experiment includes seismic data

NASA Astrophysics Data System (ADS)

Zucca, Jay

The U.S. Department of Energy detonated approximately 1.29 million kg of a commercial blasting agent, based on ammonium nitrate and fuel oil (ANFO), at the Nevada Test Site (NTS) on September 22, 1993, at 00:01.080 a.m. Pacific Daylight Time. The blasting agent was emplaced in a cylindrical chamber, approximately 15.2 m in diameter × 5.5 m high, located at 37.20193°N and 116.20986°E in a Rainier Mesa tunnel, 390 m underground. Code-named the Non-Proliferation Experiment (NPE), the explosion had an energy release of approximately 1 kt (1 kiloton = 4.186×1012 joules).

The Indefinite Extension of the Nuclear Non-Proliferation Treaty: A Hinderence or Help to Future Arms Control

NASA Astrophysics Data System (ADS)

Pella, Peter J.

1996-05-01

The indefinite and "unconditional" extension of the Nuclear Non-Proliferation Treaty (NPT) was achieved almost one year ago today. This outcome was a major foreign policy goal of the Clinton Administration. Some critics of the NPT's indefinite extension claim that nuclear weapons states parties to the NPT have now legitimized their possession of nuclear weapons for all time and that there is no incentive for future nuclear arms control and disarmament measures. A discussion of how the indefinite extension of the NPT has affected the nuclear arms control landscape and the prospects for future disarmament measures will be discussed.

Long-term proliferation and safeguards issues in future technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keisch, B.; Auerbach, C.; Fainberg, A.

1986-02-01

The purpose of the task was to assess the effect of potential new technologies, nuclear and non-nuclear, on safeguards needs and non-proliferation policies, and to explore possible solutions to some of the problems envisaged. Eight subdivisions were considered: New Enrichment Technologies; Non-Aqueous Reprocessing Technologies; Fusion; Accelerator-Driven Reactor Systems; New Reactor Types; Heavy Water and Deuterium; Long-Term Storage of Spent Fuel; and Other Future Technologies (Non-Nuclear). For each of these subdivisions, a careful review of the current world-wide effort in the field provided a means of subjectively estimating the viability and qualitative probability of fruition of promising technologies. Technologies for whichmore » safeguards and non-proliferation requirements have been thoroughly considered by others were not restudied here (e.g., the Fast Breeder Reactor). The time scale considered was 5 to 40 years for possible initial demonstration although, in some cases, a somewhat optimistic viewpoint was embraced. Conventional nuclear-material safeguards are only part of the overall non-proliferation regime. Other aspects are international agreements, export controls on sensitive technologies, classification of information, intelligence gathering, and diplomatic initiatives. The focus here is on safeguards, export controls, and classification.« less

The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells

PubMed Central

Badia, Roger; Pujantell, Maria; Riveira-Muñoz, Eva; Puig, Teresa; Torres-Torronteras, Javier; Martí, Ramón; Clotet, Bonaventura; Ampudia, Rosa M.; Ballana, Ester

2016-01-01

Macrophages are a heterogeneous cell population strongly influenced by differentiation stimuli that become susceptible to HIV-1 infection after inactivation of the restriction factor SAMHD1 by cyclin-dependent kinases (CDK). Here, we have used primary human monocyte-derived macrophages differentiated through different stimuli to evaluate macrophage heterogeneity on cell activation and proliferation and susceptibility to HIV-1 infection. Stimulation of monocytes with GM-CSF induces a non-proliferating macrophage population highly restrictive to HIV-1 infection, characterized by the upregulation of the G1/S-specific cyclin D2, known to control early steps of cell cycle progression. Knockdown of cyclin D2, enhances HIV-1 replication in GM-CSF macrophages through inactivation of SAMHD1 restriction factor by phosphorylation. Co-immunoprecipitation experiments show that cyclin D2 forms a complex with CDK4 and p21, a factor known to restrict HIV-1 replication by affecting the function of the downstream cascade that leads to SAMHD1 deactivation. Thus, we demonstrate that cyclin D2 acts as regulator of cell cycle proteins affecting SAMHD1-mediated HIV-1 restriction in non-proliferating macrophages. PMID:27541004

The Case for the Use of Active Social Media in Nonproliferation and Nuclear Security

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schanfein, Mark J.

A great amount of attention and consideration is being directed at possible applications of social media in many challenging areas. The use of social media has already shown its importance in the area of disaster response, where, each citizen is essentially acting as a sensor in reporting local conditions. In the aggregate, valuable information is obtained to enable a more effective response as well as provide timely information to those in the disaster area. No one needs to be trained to understand what constitutes a disaster, so a social media data stream from the public is literally always active andmore » ready to engage. A similar but more focused approach is the use of crowdsourcing for science, where specific challenges in areas such as mathematics, astronomy, and biology are posted to social media and solved by the crowd.« less

Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands.

PubMed

Allison, Simon J; Sadiq, Maria; Baronou, Efstathia; Cooper, Patricia A; Dunnill, Chris; Georgopoulos, Nikolaos T; Latif, Ayşe; Shepherd, Samantha; Shnyder, Steve D; Stratford, Ian J; Wheelhouse, Richard T; Willans, Charlotte E; Phillips, Roger M

2017-09-10

Organometallic complexes offer the prospect of targeting multiple pathways that are important in cancer biology. Here, the preclinical activity and mechanism(s) of action of a silver-bis(N-heterocyclic carbine) complex (Ag8) were evaluated. Ag8 induced DNA damage via several mechanisms including topoisomerase I/II and thioredoxin reductase inhibition and induction of reactive oxygen species. DNA damage induction was consistent with cytotoxicity observed against proliferating cells and Ag8 induced cell death by apoptosis. Ag8 also inhibited DNA repair enzyme PARP1, showed preferential activity against cisplatin resistant A2780 cells and potentiated the activity of temozolomide. Ag8 was substantially less active against non-proliferating non-cancer cells and selectively inhibited glycolysis in cancer cells. Ag8 also induced significant anti-tumour effects against cells implanted intraperitoneally in hollow fibres but lacked activity against hollow fibres implanted subcutaneously. Thus, Ag8 targets multiple pathways of importance in cancer biology, is less active against non-cancer cells and shows activity in vivo in a loco-regional setting. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

The Non-Proliferation Treaty review: An American perspective

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunn, L.A.

1985-01-01

Since the entry into the force in March 1970, the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) has played a central part in this decades-long endeavor. The Treaty's specific undertakings have been carefully crafted to serve its three major objectives. The first, which was the driving force behind the initial push for the NPT, is to prevent the further spread of nuclear weapons. The second is to foster peaceful nuclear cooperation under safeguards. The third objective, added during the multilateral negotiation of the NPT, is to encourage good faith negotiations to end the nuclear arms race with a viewmore » to general and complete disarmament.« less

Limiting nuclear proliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gordon, L.; Cecelski, L.

1978-01-01

As a result of the 1977 experience, it is shown that the U.S. no longer dominates the world nuclear market and must change its approach from coercion to persuasion. President Carter, implementing his campaign promises on nuclear nonproliferation, has used direct pressure, negotiated with nuclear suppliers, and asked for legislation to impose rigid criteria for the export of nuclear materials. Unilateral actions included the deferment of facilities for fuel reprocessing and breeder reactors, but were followed by efforts for international cooperation as the year progressed. While global non-proliferation policies reinforced with international technical cooperation are seen as admirable goals, themore » response to U.S. initiatives is not seen to be encouraging.« less

The nuclear weapons ban treaty and the non-proliferation regime.

PubMed

Egeland, Kjølv; Hugo, Torbjørn Graff; Løvold, Magnus; Nystuen, Gro

2018-06-18

The Treaty on the Prohibition of Nuclear Weapons (TPNW), adopted by the United Nations General Assembly in July 2017, has been met with mixed reactions. While supporters have described the Treaty as a watershed in the struggle for disarmament, others have expressed fervent opposition. One of the most serious charges levelled at the TPNW is that it will undermine the long-standing nuclear Non-Proliferation Treaty (NPT), by many regarded as a cornerstone of the international security architecture. Critics have contended that the new agreement risks eroding the system of safeguards designed to prevent the spread of nuclear weapons, derailing disarmament efforts within the NPT framework, and aggravating political division between nuclear and non-nuclear powers. Investigating the legal and political cogency of these arguments, we argue that not only may the TPNW be reconciled with existing legal instruments, the new Treaty supports and reinforces key norms and institutions on which the nuclear non-proliferation and disarmament regime is based. Furthermore, any technical challenges that might arise in the future may be addressed at meetings of states party; the drafters envisioned a dynamic process of institutional adaptations and expansion. The main challenge facing advocates of the Treaty is political: convincing the nuclear-armed states to disarm.

The Coming Nuclear Renaissance for Next Generation Safeguards Specialists--Maximizing Potential and Minimizing the Risks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eipeldauer, Mary D

2009-01-01

This document is intended to provide an overview of the workshop entitled 'The Coming Nuclear Renaissance for the Next Generation Safeguards Experts-Maximizing Benefits While Minimizing Proliferation Risks', conducted at Oak Ridge National Laboratory (ORNL) in partnership with the Y-12 National Security Complex (Y-12) and the Savannah River National Laboratory (SRNL). This document presents workshop objectives; lists the numerous participant universities and individuals, the nuclear nonproliferation lecture topics covered, and the facilities tours taken as part of the workshop; and discusses the university partnership sessions and proposed areas for collaboration between the universities and ORNL for 2009. Appendix A contains themore » agenda for the workshop; Appendix B lists the workshop attendees and presenters with contact information; Appendix C contains graphics of the evaluation form results and survey areas; and Appendix D summarizes the responses to the workshop evaluation form. The workshop was an opportunity for ORNL, Y-12, and SRNL staff with more than 30 years combined experience in nuclear nonproliferation to provide a comprehensive overview of their expertise for the university professors and their students. The overall goal of the workshop was to emphasize nonproliferation aspects of the nuclear fuel cycle and to identify specific areas where the universities and experts from operations and national laboratories could collaborate.« less

Nuclear rapprochement in Argentina and Brazil: Workshop summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

James E. Doyle

1999-10-01

On October 21 and 22, 1998, the Center for International Security Affairs at Los Alamos National Laboratory and the Center for Global Security and Cooperation at Science Applications International Corporation hosted the first of a series of work-shops on states that have chosen to roll back their pursuit of nuclear arms. The objective of the workshop series is to conduct a systematic evaluation of the roles played by U.S. nonproliferation policy in cases of nuclear rollback or restraint and to provide recommendations for future nonproliferation efforts based on lessons learned. Key attendees at the workshop included officials and former officialsmore » from the foreign ministries of Argentina and Brazil, and current and former officials from the U.S. Department of State, the Arms Control and Disarmament Agency (ACDA), and the Department of Energy (DOE). Scholars and independent researchers who have examined nuclear policy in Argentina and Brazil also participated. This workshop report includes important background information that helps set the stage for assessing nuclear policies in Argentina and Brazil. It describes national perspectives and areas of consensus and debate among the participants, particularly on the questions of lessons learned and their salience to proliferation challenges in other states. It also summarizes key questions and propositions regarding the roles played in these cases by U.S. nonproliferation policy.« less

Nuclear safeguards in Brazil and Argentina: 25 years of ABACC

NASA Astrophysics Data System (ADS)

Kassenova, Togzhan

2017-11-01

As possessors of advanced nuclear technology, Brazil and Argentina bear special responsibility for helping the international community and neighbors in their region feel confident that their nuclear programs are peaceful, secure, and safe. Over the past 25 years, the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC) has played an indispensable role in strengthening such confidence by implementing nuclear safeguards in the two countries. Today, ABACC carries out safeguards inspections at a total of 76 nuclear facilities in Brazil and Argentina. This article describes how Brazil and Argentina view trends in the global nonproliferation regime and international nuclear safeguards, and explains how these trends relate to unique challenges and opportunities facing Brazil, Argentina, and ABACC.

Report on {open_quotes}audit of internal controls over special nuclear materials{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-04-01

The Department of Energy (Department) is responsible for safeguarding a significant amount of plutonium, uranium-233 and enriched uranium - collectively referred to as special nuclear materials - stored in the United States. The Department`s office of Nonproliferation and National Security has overall management cognizance for developing policies for safeguarding these materials, while other Headquarters program offices have {open_quotes}landlord{close_quotes} responsibilities for the sites where the materials are stored, and the Department`s operations and field offices provide onsite management of contractor operations. The Department`s management and operating contractors, under the direction of the Department, safeguard and account for the special nuclear materialmore » stored at Department sites.« less

Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions.

PubMed

Groesser, Torsten; Chang, Hang; Fontenay, Gerald; Chen, James; Costes, Sylvain V; Helen Barcellos-Hoff, Mary; Parvin, Bahram; Rydberg, Bjorn

2011-07-01

To investigate γ-H2AX (phosphorylated histone H2AX) and 53BP1 (tumour protein 53 binding protein No. 1) foci formation and removal in proliferating and non-proliferating human mammary epithelial cells (HMEC) after exposure to sparsely and densely ionising radiation under different cell culture conditions. HMEC cells were grown either as monolayers (2D) or in extracellular matrix to allow the formation of acinar structures in vitro (3D). Foci numbers were quantified by image analysis at various time points after exposure. Our results reveal that in non-proliferating cells under 2D and 3D cell culture conditions, iron-ion induced γ-H2AX foci were still present at 72 h after exposure, although 53BP1 foci returned to control levels at 48 h. In contrast in proliferating HMEC, both γ-H2AX and 53BP1 foci decreased to control levels during the 24-48 h time interval after irradiation under 2D conditions. Foci numbers decreased faster after γ-ray irradiation and returned to control levels by 12 h regardless of marker, cell proliferation status, and cell culture condition. The disappearance of radiation-induced γ-H2AX and 53BP1 foci in HMEC has different dynamics that depend on radiation quality and proliferation status. Notably, the general patterns do not depend on the cell culture condition (2D versus 3D). We speculate that the persistent γ-H2AX foci in iron-ion irradiated non-proliferating cells could be due to limited availability of double-strand break (DSB) repair pathways in G0/G1-phase, or that repair of complex DSB requires replication or chromatin remodelling.

Russia`s Great Game in a nuclear South Asia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pilat, J.F.; Taylor, T.T.

1998-12-31

Lost in the noise of Pakistan`s nuclear weapon tests in the western Baluchistan desert on 28 and 30 May was a surprising diplomatic move by Russia. On 23 May, Russia became the first state to express its willingness to recognize India as a nuclear-weapon state, provided that India commits itself to the international nonproliferation regime. Russia`s Ambassador to India, Albert Chernyshev, stated in the days after the Indian but before the Pakistani nuclear tests that ``India proclaimed itself a nuclear weapons power. One now hopes that India will behave as a nuclear weapons power by acting responsibly. Every nuclear weaponsmore » state has some rights. But for getting recognition it must have some obligations. Once it is ready to show these obligations by joining the nonproliferation regime, its recognition as a nuclear weapons power will follow.`` Russia`s Great Game in South Asia in pursuit of short-term economic and other interests appears to be a serious obstacle on the path to dealing effectively with the South Asian nuclear crisis. Grave damage to security, stability and nonproliferation has already resulted from India`s and Pakistan`s actions, but the situation does not have to spiral out of control. It is imperative that the international community respond appropriately to this challenge. The international community is at a crossroads and Russia`s actions will be critical. Will it be willing to go beyond the narrow economic and political calculations reflected in its diplomatic posturing, and take actions that will serve its long-term interests by bridging differences with other great powers in order to demonstrate to India that it has not chosen the right path. If Russia decides it can gain from India`s current, perilous path and blocks or otherwise frustrates appropriate responses, the nuclear danger on the subcontinent will escalate and the global regimes to promote nonproliferation and to ban testing will be seriously, perhaps fatally, weakened with unpredictable regional and global effects.« less

Brookhaven National Laboratory

MedlinePlus

... Sciences Center for Functional Nanomaterials Chemistry Condensed Matter Physics & Materials Science National Synchrotron Light Source II Sustainable ... and Technology Nonproliferation and National Security Nuclear & Particle ... Magnet RIKEN BNL ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duggan, Ruth A

In preparation for the 2005 US/Russian Weapons Laboratories Directors Meeting, the six laboratories participating in the meeting endeavored to develop a strategy for nonproliferation technology research and development. A literature review was conducted to identify possible areas of technical collaboration and technology opportunities associated with improving nonproliferation associated with the civilian nuclear fuel cycle. The issue of multinationalization of the nuclear fuel cycle was also researched. This digest is the compilation of one-page summaries used by management of the three US nuclear weapons laboratories in preparation for strategy development. Where possible, the Web site address of the complete paper ismore » referenced.3 AcknowledgementsThe author wishes to thank Jessica Ruyle, Nancy Orlando-Gay, and Barbara Dry for their research assistance and contributions.4« less

How I Learned to Stop Worrying and Love 3D Printing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pete, Cassandra; Morrell, Sean; Maloney, Jillian

The nuclear nonproliferation regime has many robust measures in place to prevent the acquisition of a nuclear weapon, a key pillar of which is denying or preventing the transfer of technology to specific actors. Additive manufacturing (AM) is a rapidly advancing, not fully understood technology that could dramatically alter the landscape of the safeguarded fuel cycle. However, many of the benefits of AM could also be used to circumvent or defeat current safeguard practices and controls. Because the AM capability is not fully understood, research and integration is necessary early in the technology development stages in order for nonproliferation tomore » remain on the leading edge of discovery and not the tail end of technology deployment.« less

The Lifecycle of Bayesian Network Models Developed for Multi-Source Signature Assessment of Nuclear Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gastelum, Zoe N.; White, Amanda M.; Whitney, Paul D.

2013-06-04

The Multi-Source Signatures for Nuclear Programs project, part of Pacific Northwest National Laboratory’s (PNNL) Signature Discovery Initiative, seeks to computationally capture expert assessment of multi-type information such as text, sensor output, imagery, or audio/video files, to assess nuclear activities through a series of Bayesian network (BN) models. These models incorporate knowledge from a diverse range of information sources in order to help assess a country’s nuclear activities. The models span engineering topic areas, state-level indicators, and facility-specific characteristics. To illustrate the development, calibration, and use of BN models for multi-source assessment, we present a model that predicts a country’s likelihoodmore » to participate in the international nuclear nonproliferation regime. We validate this model by examining the extent to which the model assists non-experts arrive at conclusions similar to those provided by nuclear proliferation experts. We also describe the PNNL-developed software used throughout the lifecycle of the Bayesian network model development.« less

Leo Szilard Lectureship Award Talk: Nuclear disarmament after the cold war

NASA Astrophysics Data System (ADS)

Podvig, Pavel

2008-04-01

Now that the cold war is long over, our thinking of nuclear weapons and the role that they play in international security has undergone serious changes. The emphasis has shifted from superpower confrontation to nuclear proliferation, spread of weapon materials, and to the dangers of countries developing nuclear weapon capability under a cover of a civilian program. At the same time, the old cold-war dangers, while receded, have not disappeared completely. The United States and Russia keep maintaining thousands of nuclear weapons in their arsenals, some of them in very high degree of readiness. This situation presents a serious challenge that the international community has to deal with. Although Russia and the United States are taking some steps to reduce their nuclear arsenals, the traditional arms control process has stalled -- the last treaty that was signed in 2002 does not place serious limits on strategic forces of either side. The START Treaty, which provides a framework for verification and transparency in reduction of nuclear arsenals, will expire at the end of 2009. Little effort has been undertaken to extend the treaty or renegotiate it. Moreover, in recent years Russia has stepped up the efforts to modernize its strategic nuclear forces. The United States has resisted joining the Comprehensive Nuclear Test Ban Treaty and has been working on controversial new nuclear weapon development programs. The U.S. missile defense program makes the dialogue between Russia and the United States even more difficult. The reluctance of Russia and the United States to engage in a discussion about drastic reductions of their nuclear forces undermines the case of nuclear nonproliferation and seriously complicated their effort to contain the spread of nuclear weapon technologies and expertise. One of the reasons for the current lack of progress in nuclear disarmament is the contradiction between the diminished role that nuclear weapons play in security of nuclear weapon states and the inertia of cold-war institutions that are involved in their development and support. Dealing with this contradiction would require development of new mechanisms of cooperation between nuclear weapons states and their strong commitment to the cause of nuclear nonproliferation. One important area of cooperation is development of a framework that would prevent the spread of nuclear materials and technology at the time when increasing number of countries is turning toward expanded use of nuclear power to cover their energy needs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hund, Gretchen

For the past decade, a team at the Pacific Northwest National Laboratory (PNNL) has engaged industry to “go beyond compliance” in controlling and securing their supply chains to ensure their goods are not diverted to nuclear weapons programs. This work has focused on dual-use industries that manufacture products that can be used in both commercial applications and in the development of a nuclear weapon. The team encourages industry to self-regulate to reduce proliferation risks. As part of that work, PNNL interviewed numerous companies about their compliance practices in order to understand their business and to build awareness around best practicesmore » to ensure security of goods and information along their supply chains. As a result, PNNL has identified seven indicators that a company can adopt as part of their commitment to nonproliferation ideals.« less

International data collection and analysis. Task 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-04-01

Commercial nuclear power has grown to the point where 13 nations now operate commercial nuclear power plants. Another four countries should join this list before the end of 1980. In the Nonproliferation Alternative Systems Assessment Program (NASAP), the US DOE is evaluating a series of alternate possible power systems. The objective is to determine practical nuclear systems which could reduce proliferation risk while still maintaining the benefits of nuclear power. Part of that effort is the development of a data base denoting the energy needs, resources, technical capabilities, commitment to nuclear power, and projected future trends for various non-US countries.more » The data are presented by country for each of 28 non-US countries. This volume contains compiled data on Mexico, Netherlands, Pakistan, Philippines, South Africa, South Korea, and Spain.« less

Sandia Technology engineering and science accomplishments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report briefly discusses the following research being conducted at Sandia Laboratories: Advanced Manufacturing -- Sandia technology helps keep US industry in the lead; Microelectronics-Sandia`s unique facilities transform research advances into manufacturable products; Energy -- Sandia`s energy programs focus on strengthening industrial growth and political decisionmaking; Environment -- Sandia is a leader in environmentally conscious manufacturing and hazardous waste reduction; Health Care -- New biomedical technologies help reduce cost and improve quality of health care; Information & Computation -- Sandia aims to help make the information age a reality; Transportation -- This new initiative at the Labs will help improvemore » transportation, safety,l efficiency, and economy; Nonproliferation -- Dismantlement and arms control are major areas of emphasis at Sandia; and Awards and Patents -- Talented, dedicated employees are the backbone of Sandia`s success.« less

An analysis of international nuclear fuel supply options

NASA Astrophysics Data System (ADS)

Taylor, J'tia Patrice

As the global demand for energy grows, many nations are considering developing or increasing nuclear capacity as a viable, long-term power source. To assess the possible expansion of nuclear power and the intricate relationships---which cover the range of economics, security, and material supply and demand---between established and aspirant nuclear generating entities requires models and system analysis tools that integrate all aspects of the nuclear enterprise. Computational tools and methods now exist across diverse research areas, such as operations research and nuclear engineering, to develop such a tool. This dissertation aims to develop methodologies and employ and expand on existing sources to develop a multipurpose tool to analyze international nuclear fuel supply options. The dissertation is comprised of two distinct components: the development of the Material, Economics, and Proliferation Assessment Tool (MEPAT), and analysis of fuel cycle scenarios using the tool. Development of MEPAT is aimed for unrestricted distribution and therefore uses publicly available and open-source codes in its development when possible. MEPAT is built using the Powersim Studio platform that is widely used in systems analysis. MEPAT development is divided into three modules focusing on: material movement; nonproliferation; and economics. The material movement module tracks material quantity in each process of the fuel cycle and in each nuclear program with respect to ownership, location and composition. The material movement module builds on techniques employed by fuel cycle models such as the Verifiable Fuel Cycle Simulation (VISION) code developed at the Idaho National Laboratory under the Advanced Fuel Cycle Initiative (AFCI) for the analysis of domestic fuel cycle. Material movement parameters such as lending and reactor preference, as well as fuel cycle parameters such as process times and material factors are user-specified through a Microsoft Excel(c) data spreadsheet. The material movement module is the largest of the three, and the two other modules that assess nonproliferation and economics of the options are dependent on its output. Proliferation resistance measures from literature are modified and incorporated in MEPAT. The module to assess the nonproliferation of the supply options allows the user to specify defining attributes for the fuel cycle processes, and determines significant quantities of materials as well as measures of proliferation resistance. The measure is dependent on user-input and material information. The economics module allows the user to specify costs associated with different processes and other aspects of the fuel cycle. The simulation tool then calculates economic measures that relate the cost of the fuel cycle to electricity production. The second part of this dissertation consists of an examination of four scenarios of fuel supply option using MEPAT. The first is a simple scenario illustrating the modules and basic functions of MEPAT. The second scenario recreates a fuel supply study reported earlier in literature, and compares MEPAT results with those reported earlier for validation. The third, and a rather realistic, scenario includes four nuclear programs with one program entering the nuclear energy market. The fourth scenario assesses the reactor options available to the Hashemite Kingdom of Jordan, which is currently assessing available options to introduce nuclear power in the country. The methodology developed and implemented in MEPAT to analyze the material, proliferation and economics of nuclear fuel supply options is expected to help simplify and assess different reactor and fuel options available to utilities, government agencies and international organizations.

Nuclear nonproliferation: India Pakistan. Research report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fallon, J.S.

1997-04-01

As most of the world continues to seek ways to reduce or eliminate the spread of nuclear weapons, two countries seem intent on pursuing a path which is contradictory. India and Pakistan, two neighboring and frequently warring nations, condemn the use of nuclear weapons as they continue to develop the capability to deliver a nuclear payload. Additionally, India has stood against the Non-Proliferation Treaty, insisting that all nations must agree to eliminate nuclear weapons. It is against this seemingly hopeless situation that this report is focused. How can nuclear proliferation in South Asia be diffused while answering the security concernsmore » of both India and Pakistan. What I offer here is a review of the history, the current situation for the area, and a proposed solution to this nuclear stalemate.« less

Nuclear Arms Control, Nonproliferation, and Counterterrorism: Impacts on Public Health

PubMed Central

Pregenzer, Arian

2014-01-01

Reducing the risks of nuclear war, limiting the spread of nuclear weapons, and reducing global nuclear weapons stockpiles are key national and international security goals. They are pursued through a variety of international arms control, nonproliferation, and counterterrorism treaties and agreements. These legally binding and political commitments, together with the institutional infrastructure that supports them, work to establish global norms of behavior and have limited the spread of weapons of mass destruction. Beyond the primary security objectives, reducing the likelihood of the use of nuclear weapons, preventing environmental releases of radioactive material, increasing the availability of safe and secure nuclear technology for peaceful purposes, and providing scientific data relevant to predicting and managing the consequences of natural or human-caused disasters worldwide provide significant benefits to global public health. PMID:24524501

Preliminary results of calculations for heavy-water nuclear-power-plant reactors employing 235U, 233U, and 232Th as a fuel and meeting requirements of a nonproliferation of nuclear weapons

NASA Astrophysics Data System (ADS)

Ioffe, B. L.; Kochurov, B. P.

2012-02-01

A physical design is developed for a gas-cooled heavy-water nuclear reactor intended for a project of a nuclear power plant. As a fuel, the reactor would employ thorium with a small admixture of enriched uranium that contains not more than 20% of 235U. It operates in the open-cycle mode involving 233U production from thorium and its subsequent burnup. The reactor meets the conditions of a nonproliferation of nuclear weapons: the content of fissionable isotopes in uranium at all stages of the process, including the final one, is below the threshold for constructing an atomic bomb, the amount of product plutonium being extremely small.

Nevada National Security Site Environmental Report 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wills

This Nevada National Security Site Environmental Report (NNSSER) was prepared to satisfy DOE Order DOE O 231.1B, “Environment, Safety and Health Reporting.” Its purpose is to (1) report compliance status with environmental standards and requirements, (2) present results of environmental monitoring of radiological and nonradiological effluents, (3) report estimated radiological doses to the public from releases of radioactive material, (4) summarize environmental incidents of noncompliance and actions taken in response to them, (5) describe the National Nuclear Security Administration Nevada Field Office (NNSA/NFO) Environmental Management System and characterize its performance, and (6) highlight significant environmental programs and efforts. This NNSSERmore » summarizes data and compliance status for calendar year 2016 at the Nevada National Security Site (NNSS) and its two Nevada-based support facilities, the North Las Vegas Facility (NLVF) and the Remote Sensing Laboratory–Nellis (RSL-Nellis). It also addresses environmental restoration (ER) projects conducted at the Tonopah Test Range (TTR) and the Nevada Test and Training Range (NTTR). NNSA/NFO directs the management and operation of the NNSS and six sites across the nation. In addition to the NNSA itself, the six sites include two in Nevada (NLVF and RSL-Nellis) and four in other states (RSL-Andrews in Maryland, Livermore Operations in California, Los Alamos Operations in New Mexico, and Special Technologies Laboratory in California). Los Alamos, Lawrence Livermore, and Sandia National Laboratories are the principal organizations that sponsor and implement the nuclear weapons programs at the NNSS. National Security Technologies, LLC (NSTec), is the current Management and Operating contractor accountable for the successful execution of work and ensuring that work is performed in compliance with environmental regulations. The six sites all provide support to enhance the NNSS as a location for its multiple missions. The three major NNSS missions include National Security/Defense, Environmental Management, and Nondefense. The major programs that support these missions are Stockpile Stewardship and Management, Nonproliferation and Counterterrorism, Nuclear Emergency Response, Strategic Partnership Projects, Environmental Restoration, Waste Management, Conservation and Renewable Energy, Other Research and Development, and Infrastructure. The major facilities that support the programs include the U1a Facility, Big Explosives Experimental Facility (BEEF), Device Assembly Facility, Dense Plasma Focus Facility, Joint Actinide Shock Physics Experimental Research Facility, Radiological/Nuclear Countermeasures Test and Evaluation Complex, Nonproliferation Test and Evaluation Complex (NPTEC), Radiological/Nuclear Weapons of Mass Destruction Incident Exercise Site, the Area 5 Radioactive Waste Management Complex (RWMC), and the Area 3 Radioactive Waste Management Site (RWMS).« less

Technical solutions to nonproliferation challenges

NASA Astrophysics Data System (ADS)

Satkowiak, Lawrence

2014-05-01

The threat of nuclear terrorism is real and poses a significant challenge to both U.S. and global security. For terrorists, the challenge is not so much the actual design of an improvised nuclear device (IND) but more the acquisition of the special nuclear material (SNM), either highly enriched uranium (HEU) or plutonium, to make the fission weapon. This paper provides two examples of technical solutions that were developed in support of the nonproliferation objective of reducing the opportunity for acquisition of HEU. The first example reviews technologies used to monitor centrifuge enrichment plants to determine if there is any diversion of uranium materials or misuse of facilities to produce undeclared product. The discussion begins with a brief overview of the basics of uranium processing and enrichment. The role of the International Atomic Energy Agency (IAEA), its safeguard objectives and how the technology evolved to meet those objectives will be described. The second example focuses on technologies developed and deployed to monitor the blend down of 500 metric tons of HEU from Russia's dismantled nuclear weapons to reactor fuel or low enriched uranium (LEU) under the U.S.-Russia HEU Purchase Agreement. This reactor fuel was then purchased by U.S. fuel fabricators and provided about half the fuel for the domestic power reactors. The Department of Energy established the HEU Transparency Program to provide confidence that weapons usable HEU was being blended down and thus removed from any potential theft scenario. Two measurement technologies, an enrichment meter and a flow monitor, were combined into an automated blend down monitoring system (BDMS) and were deployed to four sites in Russia to provide 24/7 monitoring of the blend down. Data was downloaded and analyzed periodically by inspectors to provide the assurances required.

Technical solutions to nonproliferation challenges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Satkowiak, Lawrence

2014-05-09

The threat of nuclear terrorism is real and poses a significant challenge to both U.S. and global security. For terrorists, the challenge is not so much the actual design of an improvised nuclear device (IND) but more the acquisition of the special nuclear material (SNM), either highly enriched uranium (HEU) or plutonium, to make the fission weapon. This paper provides two examples of technical solutions that were developed in support of the nonproliferation objective of reducing the opportunity for acquisition of HEU. The first example reviews technologies used to monitor centrifuge enrichment plants to determine if there is any diversionmore » of uranium materials or misuse of facilities to produce undeclared product. The discussion begins with a brief overview of the basics of uranium processing and enrichment. The role of the International Atomic Energy Agency (IAEA), its safeguard objectives and how the technology evolved to meet those objectives will be described. The second example focuses on technologies developed and deployed to monitor the blend down of 500 metric tons of HEU from Russia's dismantled nuclear weapons to reactor fuel or low enriched uranium (LEU) under the U.S.-Russia HEU Purchase Agreement. This reactor fuel was then purchased by U.S. fuel fabricators and provided about half the fuel for the domestic power reactors. The Department of Energy established the HEU Transparency Program to provide confidence that weapons usable HEU was being blended down and thus removed from any potential theft scenario. Two measurement technologies, an enrichment meter and a flow monitor, were combined into an automated blend down monitoring system (BDMS) and were deployed to four sites in Russia to provide 24/7 monitoring of the blend down. Data was downloaded and analyzed periodically by inspectors to provide the assurances required.« less

In search of plutonium: A nonproliferation journey

NASA Astrophysics Data System (ADS)

Hecker, Siegfried

2010-02-01

In February 1992, I landed in the formerly secret city of Sarov, the Russian Los Alamos, followed a few days later by a visit to Snezhinsk, their Livermore. The briefings we received of the Russian nuclear weapons program and tours of their plutonium, reactor, explosives, and laser facilities were mind boggling considering the Soviet Union was dissolved only two months earlier. This visit began a 17-year, 41 journey relationship with the Russian nuclear complex dedicated to working with them in partnership to protect and safeguard their weapons and fissile materials, while addressing the plight of their scientists and engineers. In the process, we solved a forty-year disagreement about the plutonium-gallium phase diagram and began a series of fundamental plutonium science workshops that are now in their tenth year. At the Yonbyon reprocessing facility in January 2004, my North Korean hosts had hoped to convince me that they have a nuclear deterrent. When I expressed skepticism, they asked if I wanted to see their ``product.'' I asked if they meant the plutonium; they replied, ``Well, yes.'' Thus, I wound up holding 200 grams of North Korean plutonium (in a sealed glass jar) to make sure it was heavy and warm. So began the first of my six journeys to North Korea to provide technical input to the continuing North Korean nuclear puzzle. In Trombay and Kalpakkam a few years later I visited the Indian nuclear research centers to try to understand how India's ambitious plans for nuclear power expansion can be accomplished safely and securely. I will describe these and other attempts to deal with the nonproliferation legacy of the cold war and the new challenges ahead. )

Strengthening Software Authentication with the ROSE Software Suite

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G

2006-06-15

Many recent nonproliferation and arms control software projects include a software authentication regime. These include U.S. Government-sponsored projects both in the United States and in the Russian Federation (RF). This trend toward requiring software authentication is only accelerating. Demonstrating assurance that software performs as expected without hidden ''backdoors'' is crucial to a project's success. In this context, ''authentication'' is defined as determining that a software package performs only its intended purpose and performs said purpose correctly and reliably over the planned duration of an agreement. In addition to visual inspections by knowledgeable computer scientists, automated tools are needed to highlightmore » suspicious code constructs, both to aid visual inspection and to guide program development. While many commercial tools are available for portions of the authentication task, they are proprietary and not extensible. An open-source, extensible tool can be customized to the unique needs of each project (projects can have both common and custom rules to detect flaws and security holes). Any such extensible tool has to be based on a complete language compiler. ROSE is precisely such a compiler infrastructure developed within the Department of Energy (DOE) and targeted at the optimization of scientific applications and user-defined libraries within large-scale applications (typically applications of a million lines of code). ROSE is a robust, source-to-source analysis and optimization infrastructure currently addressing large, million-line DOE applications in C and C++ (handling the full C, C99, C++ languages and with current collaborations to support Fortran90). We propose to extend ROSE to address a number of security-specific requirements, and apply it to software authentication for nonproliferation and arms control projects.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lakamp, M.A.

The United States has adopted a policy of calculated ambiguity regarding the role of nuclear weapons in response to a potential chemical or biological weapons (CBW) attack. Many factors affect decisions about the role nuclear weapons play in US counterproliferation strategy. This thesis describes the policy of calculated ambiguity and offers some observations about its prospects and pitfalls. The thesis presents evidence that suggests nuclear weapons could play a positive role in the US counterproliferation strategy, at least in some circumstances. It also explains how such a role could conflict with the US nonproliferation strategy. Such a role would alsomore » violate the nuclear taboo and be seen by a majority of countries as illegal and immoral. The United States has chosen a policy of calculated ambiguity in an attempt to retain the deterrent value of nuclear weapons without paying the political, legal, and moral costs of explicit reliance on nuclear weapons to deter the use of CBW. This may have short-term benefits, but ultimately may damage the national interest.« less

Analytical and Radiochemistry for Nuclear Forensics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steiner, Robert Ernest; Dry, Donald E.; Kinman, William Scott

Information about nonproliferation nuclear forensics, activities in forensics at Los Alamos National Laboratory, radio analytical work at LANL, radiochemical characterization capabilities, bulk chemical and materials analysis capabilities, and future interests in forensics interactions.

31 CFR 588.304 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Tariff Schedule of the United States. (b) The term information or informational materials, with respect... promote the nonproliferation or antiterrorism policies of the United States; or (2) With respect to which...

Case Study: Iran, Islam, the NPT, and the Bomb

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saunders, E .

2011-04-01

The goals of this case study are: (1) To examine the correlation between Iran's nuclear program and clerical statements; (2) To evaluate the importance of these statements; (3) To understand the relationship between policy and fatwas (Islamic decrees); (4) To address the issue of a 'nuclear fatwa'; and (5) To examine how, if at all, Sharia (Islamic law) has influenced Iran's actions or inactions with respect to the Non-Proliferation Treaty (NPT), the International Atomic Energy Agency (IAEA), and Iran's adherence to its IAEA Safeguards Agreements and the Additional Protocol. The Islamic Republic of Iran (hereinafter Iran) is one of twomore » theocracies in the world, the second being Vatican City. Iran's government derives its constitutional, moral, and political legitimacy from Islam. As a result of this theocratic culture, rules are set and interpreted with a much different calibrator than that of the Western world. Islam affects all aspects of Iranian life. This is further complicated by the fact that Islam is not a nationalistic faith, in that many people all over the world believe in and adhere to Islamic principles. As a result, a political system that derives much of its fervor from being nationalistic is caught between two worlds, one within the land boundaries of Iran and the other within a faith that transcends boundaries. Thus, any understanding of Islamic law must first be understood within this delicate balance of nationalism and transcendence. Iran has found itself on the international stage concerning its nuclear program. Because Iran is a theocratic state, it is imperative to examine its political moves, speeches, rights, and obligations through the lens of Islam. This study will examine how Islam plays a role in Iran's dealing with the International Atomic Energy Agency (IAEA), its understanding of the Nuclear Non-Proliferation Treaty (NPT), including parties obligations under Safeguards Agreements and the Additional Protocol, and also provide a recommendation on how to move forward in dealings with Iran based in part on an understanding of Islamic principles.« less

Oak Ridge National Laboratory Office of International Nuclear Safeguards: Human Capital Development Activity in FY16

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilligan, Kimberly V.; Gaudet, Rachel N.

In 2007, the U.S. Department of Energy National Nuclear Security Administration (DOE NNSA) Office of Nonproliferation and Arms Control (NPAC) completed a comprehensive review of the current and potential future challenges facing the international safeguards system. One of the report’s key recommendations was for DOE NNSA to launch a major new program to revitalize the international safeguards technology and human resource base. In 2007, at the International Atomic Energy Agency (IAEA) General Conference, then Secretary of Energy Samuel W. Bodman announced the newly created Next Generation Safeguards Initiative (NGSI). NGSI consists of five program elements: policy development and outreach, conceptsmore » and approaches, technology and analytical methodologies, human capital development (HCD), and infrastructure development. This report addresses the HCD component of NGSI. The goal of the HCD component as defined in the NNSA Program Plan is “to revitalize and expand the international safeguards human capital base by attracting and training a new generation of talent.” The major objectives listed in the HCD goal include education and training, outreach to universities and professional societies, postdoctoral appointments, and summer internships at national laboratories.« less

Nuclear programs in India and Pakistan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mian, Zia

India and Pakistan launched their respective nuclear programs in the 1940s and 1950s with considerable foreign technical support, especially from the United States Atoms for Peace Program. The technology and training that was acquired served as the platform for later nuclear weapon development efforts that included nuclear weapon testing in 1974 and in 1998 by India, and also in 1998 by Pakistan - which had illicitly acquired uranium enrichment technology especially from Europe and received assistance from China. As of 2013, both India and Pakistan were continuing to produce fissile material for weapons, in the case of India also formore » nuclear naval fuel, and were developing a diverse array of ballistic and cruise missiles. International efforts to restrain the South Asian nuclear build-up have been largely set aside over the past decade as Pakistani support became central for the U.S. war in Afghanistan and as U.S. geopolitical and economic interests in supporting the rise of India, in part as a counter to China, led to India being exempted both from U.S non-proliferation laws and international nuclear trade guidelines. In the absence of determined international action and with Pakistan blocking the start of talks on a fissile material cutoff treaty, nuclear weapon programs in South Asia are likely to keep growing for the foreseeable future.« less

Nuclear programs in India and Pakistan

NASA Astrophysics Data System (ADS)

Mian, Zia

2014-05-01

India and Pakistan launched their respective nuclear programs in the 1940s and 1950s with considerable foreign technical support, especially from the United States Atoms for Peace Program. The technology and training that was acquired served as the platform for later nuclear weapon development efforts that included nuclear weapon testing in 1974 and in 1998 by India, and also in 1998 by Pakistan - which had illicitly acquired uranium enrichment technology especially from Europe and received assistance from China. As of 2013, both India and Pakistan were continuing to produce fissile material for weapons, in the case of India also for nuclear naval fuel, and were developing a diverse array of ballistic and cruise missiles. International efforts to restrain the South Asian nuclear build-up have been largely set aside over the past decade as Pakistani support became central for the U.S. war in Afghanistan and as U.S. geopolitical and economic interests in supporting the rise of India, in part as a counter to China, led to India being exempted both from U.S non-proliferation laws and international nuclear trade guidelines. In the absence of determined international action and with Pakistan blocking the start of talks on a fissile material cutoff treaty, nuclear weapon programs in South Asia are likely to keep growing for the foreseeable future.

70 Years of Making the World Safer

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This video shows our roles in making the world safer — working to end World War II, providing stable isotopes for research, providing unique precision manufacturing capabilities, and meeting nonproliferation and global security missions.

31 CFR 544.304 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., 9702, or 9703 of the Harmonized Tariff Schedule of the United States. (b) The term information or... that such controls promote the nonproliferation or antiterrorism policies of the United States; or (2...

31 CFR 537.308 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... materials, artworks must be classified under chapter heading 9701, 9702, or 9703 of the Harmonized Tariff... nonproliferation or antiterrorism policies of the United States; or (2) With respect to which acts are prohibited...

31 CFR 548.304 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... materials, artworks must be classified under chapter heading 9701, 9702, or 9703 of the Harmonized Tariff... nonproliferation or antiterrorism policies of the United States; or (2) With respect to which acts are prohibited...

31 CFR 545.305 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... materials, artworks must be classified under chapter heading 9701, 9702, or 9703 of the Harmonized Tariff... nonproliferation or antiterrorism policies of the United States; or (2) With respect to which acts are prohibited...

31 CFR 587.304 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... heading 9701, 9702, or 9703 of the Harmonized Tariff Schedule of the United States. (b) The term... the EAA to the extent that such controls promote the nonproliferation or antiterrorism policies of the...

31 CFR 586.309 - Information and informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., 9702, or 9703 of the Harmonized Tariff Schedule of the United States. (b) The term information and... controls promote nonproliferation or antiterrorism policies of the United States. (2) With respect to which...

31 CFR 541.304 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... materials, artworks must be classified under chapter heading 9701, 9702, or 9703 of the Harmonized Tariff... nonproliferation or antiterrorism policies of the United States; or (2) With respect to which acts are prohibited...

Technical cooperation on nuclear security between the United States and China : review of the past and opportunities for the future.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pregenzer, Arian Leigh

2011-12-01

The United States and China are committed to cooperation to address the challenges of the next century. Technical cooperation, building on a long tradition of technical exchange between the two countries, can play an important role. This paper focuses on technical cooperation between the United States and China in the areas of nonproliferation, arms control and other nuclear security topics. It reviews cooperation during the 1990s on nonproliferation and arms control under the U.S.-China Arms Control Exchange, discusses examples of ongoing activities under the Peaceful Uses of Technology Agreement to enhance security of nuclear and radiological material, and suggests opportunitiesmore » for expanding technical cooperation between the defense nuclear laboratories of both countries to address a broader range of nuclear security topics.« less

Developments in capture-γ libraries for nonproliferation applications

NASA Astrophysics Data System (ADS)

Hurst, A. M.; Firestone, R. B.; Sleaford, B. W.; Bleuel, D. L.; Basunia, M. S.; Bečvář, F.; Belgya, T.; Bernstein, L. A.; Carroll, J. J.; Detwiler, B.; Escher, J. E.; Genreith, C.; Goldblum, B. L.; Krtička, M.; Lerch, A. G.; Matters, D. A.; McClory, J. W.; McHale, S. R.; Révay, Zs.; Szentmiklosi, L.; Turkoglu, D.; Ureche, A.; Vujic, J.

2017-09-01

The neutron-capture reaction is fundamental for identifying and analyzing the γ-ray spectrum from an unknown assembly because it provides unambiguous information on the neutron-absorbing isotopes. Nondestructive-assay applications may exploit this phenomenon passively, for example, in the presence of spontaneous-fission neutrons, or actively where an external neutron source is used as a probe. There are known gaps in the Evaluated Nuclear Data File libraries corresponding to neutron-capture γ-ray data that otherwise limit transport-modeling applications. In this work, we describe how new thermal neutron-capture data are being used to improve information in the neutron-data libraries for isotopes relevant to nonproliferation applications. We address this problem by providing new experimentally-deduced partial and total neutron-capture reaction cross sections and then evaluate these data by comparison with statistical-model calculations.

Nuclear Arms Control, Nonproliferation, and Counterterrorism: Impacts on Public Health

DOE PAGES

Dreicer, Mona; Pregenzer, Arian

2014-04-01

Reducing the risks of nuclear war, limiting the spread of nuclear weapons and reducing global nuclear weapons stockpiles are key national and international security goals. They are pursued through a variety of international arms control, nonproliferation and counter-terrorism treaties and agreements. These legally binding and political commitments, together with the institutional infrastructure that supports them, work to establish global norms of behavior and have limited the spread of weapons of mass destruction. Beyond the primary security objectives, reducing the likelihood of the use of nuclear weapons, preventing environmental releases of radioactive material, increasing the availability of safe and secure nuclearmore » technology for peaceful purposes, and providing scientific data relevant to predicting and managing the consequences of natural or human-caused disasters world-wide provide significant benefits to global public health.« less

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia

PubMed Central

Cole, John J.; Nelson, David M.; Dikovskaya, Dina; Faller, William J.; Vizioli, Maria Grazia; Hewitt, Rachael N.; Anannya, Orchi; McBryan, Tony; Manoharan, Indrani; van Tuyn, John; Morrice, Nicholas; Pchelintsev, Nikolay A.; Ivanov, Andre; Brock, Claire; Drotar, Mark E.; Nixon, Colin; Clark, William; Sansom, Owen J.; Anderson, Kurt I.; King, Ayala; Blyth, Karen

2014-01-01

Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. Cellular senescence and associated tumor suppression depend on control of chromatin. Histone chaperone HIRA deposits variant histone H3.3 and histone H4 into chromatin in a DNA replication-independent manner. Appropriately for a DNA replication-independent chaperone, HIRA is involved in control of chromatin in nonproliferating senescent cells, although its role is poorly defined. Here, we show that nonproliferating senescent cells express and incorporate histone H3.3 and other canonical core histones into a dynamic chromatin landscape. Expression of canonical histones is linked to alternative mRNA splicing to eliminate signals that confer mRNA instability in nonproliferating cells. Deposition of newly synthesized histones H3.3 and H4 into chromatin of senescent cells depends on HIRA. HIRA and newly deposited H3.3 colocalize at promoters of expressed genes, partially redistributing between proliferating and senescent cells to parallel changes in expression. In senescent cells, but not proliferating cells, promoters of active genes are exceptionally enriched in H4K16ac, and HIRA is required for retention of H4K16ac. HIRA is also required for retention of H4K16ac in vivo and suppression of oncogene-induced neoplasia. These results show that HIRA controls a specialized, dynamic H4K16ac-decorated chromatin landscape in senescent cells and enforces tumor suppression. PMID:25512559

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.

PubMed

Rai, Taranjit Singh; Cole, John J; Nelson, David M; Dikovskaya, Dina; Faller, William J; Vizioli, Maria Grazia; Hewitt, Rachael N; Anannya, Orchi; McBryan, Tony; Manoharan, Indrani; van Tuyn, John; Morrice, Nicholas; Pchelintsev, Nikolay A; Ivanov, Andre; Brock, Claire; Drotar, Mark E; Nixon, Colin; Clark, William; Sansom, Owen J; Anderson, Kurt I; King, Ayala; Blyth, Karen; Adams, Peter D

2014-12-15

Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. Cellular senescence and associated tumor suppression depend on control of chromatin. Histone chaperone HIRA deposits variant histone H3.3 and histone H4 into chromatin in a DNA replication-independent manner. Appropriately for a DNA replication-independent chaperone, HIRA is involved in control of chromatin in nonproliferating senescent cells, although its role is poorly defined. Here, we show that nonproliferating senescent cells express and incorporate histone H3.3 and other canonical core histones into a dynamic chromatin landscape. Expression of canonical histones is linked to alternative mRNA splicing to eliminate signals that confer mRNA instability in nonproliferating cells. Deposition of newly synthesized histones H3.3 and H4 into chromatin of senescent cells depends on HIRA. HIRA and newly deposited H3.3 colocalize at promoters of expressed genes, partially redistributing between proliferating and senescent cells to parallel changes in expression. In senescent cells, but not proliferating cells, promoters of active genes are exceptionally enriched in H4K16ac, and HIRA is required for retention of H4K16ac. HIRA is also required for retention of H4K16ac in vivo and suppression of oncogene-induced neoplasia. These results show that HIRA controls a specialized, dynamic H4K16ac-decorated chromatin landscape in senescent cells and enforces tumor suppression. © 2014 Rai et al.; Published by Cold Spring Harbor Laboratory Press.

Laboratory directed research and development FY98 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R; Holzrichter, J

1999-05-01

In 1984, Congress and the Department of Energy (DOE) established the Laboratory Directed Research and Development (LDRD) Program to enable the director of a national laboratory to foster and expedite innovative research and development (R and D) in mission areas. The Lawrence Livermore National Laboratory (LLNL) continually examines these mission areas through strategic planning and shapes the LDRD Program to meet its long-term vision. The goal of the LDRD Program is to spur development of new scientific and technical capabilities that enable LLNL to respond to the challenges within its evolving mission areas. In addition, the LDRD Program provides LLNLmore » with the flexibility to nurture and enrich essential scientific and technical competencies and enables the Laboratory to attract the most qualified scientists and engineers. The FY98 LDRD portfolio described in this annual report has been carefully structured to continue the tradition of vigorously supporting DOE and LLNL strategic vision and evolving mission areas. The projects selected for LDRD funding undergo stringent review and selection processes, which emphasize strategic relevance and require technical peer reviews of proposals by external and internal experts. These FY98 projects emphasize the Laboratory's national security needs: stewardship of the U.S. nuclear weapons stockpile, responsibility for the counter- and nonproliferation of weapons of mass destruction, development of high-performance computing, and support of DOE environmental research and waste management programs.« less

The nuclear issue: where do we go from here?.

PubMed

Rotblat, Joseph

2003-01-01

The drive for the elimination of nuclear weapons is going badly and there is currently little support from the general public. The United States Nuclear Posture Review incorporates nuclear capability into conventional war planning. The Stockpile Stewardship Program is designed to maintain nuclear weapon capability. The US is planning an essentially new earth-penetrating nuclear weapon and is prepared to test this in the national interest if thought necessary. These policies could stimulate nuclear proliferation by others, do nothing to deter terrorism, promote persisting polarization of the world, are a clear breach of the Non-Proliferation Treaty and rest world security on a continued balance of terror. A renewed mass campaign to counteract all this, on legal and moral grounds in particular, is urgently needed. IPPNW and kindred organizations must restore sanity in our policies and humanity to our actions.

Fuel Cycle Technologies 2014 Achievement Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hong, Bonnie C.

2015-01-01

The Fuel Cycle Technologies (FCT) program supports the Department of Energy’s (DOE’s) mission to: “Enhance U.S. security and economic growth through transformative science, technology innovation, and market solutions to meet our energy, nuclear security, and environmental challenges.” Goal 1 of DOE’s Strategic Plan is to innovate energy technologies that enhance U.S. economic growth and job creation, energy security, and environmental quality. FCT does this by investing in advanced technologies that could transform the nuclear fuel cycle in the decades to come. Goal 2 of DOE’s Strategic Plan is to strengthen national security by strengthening key science, technology, and engineering capabilities.more » FCT does this by working closely with the National Nuclear Security Administration and the U.S Department of State to develop advanced technologies that support the Nation’s nuclear nonproliferation goals.« less

Preventing ballistic missile proliferation: Lessons from Iraq. Master`s thesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talay, B.J.

1996-12-01

This thesis examines the case of Iraq to assess the performance of the missile nonproliferation regime since 1970. By analyzing the methods used by Iraq to obtain missile systems and missile technology, this thesis assesses the ability of the international community to prevent ballistic missile proliferation. Understanding Iraq`s past capabilities as well as its post-war efforts to rebuild weapons programs and procurement networks, this thesis provides suggestions for improving the regime`s performance. This thesis finds that (1) prior to 1992, the Missile Technology Control Regime (MTCR) failed in its attempts to prevent proliferation; (2) the existence of the MTCR, whilemore » necessary to slow proliferation, is not sufficient to prevent proliferation; and (3) additional enforcement is needed to counter weapons of mass destruction acquisition by resourceful and determined states.« less

31 CFR 542.304 - Information or informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., artworks must be classified under chapter heading 9701, 9702, or 9703 of the Harmonized Tariff Schedule of... nonproliferation or antiterrorism policies of the United States; or (2) With respect to which acts are prohibited...

77 FR 2271 - Technical Advisory Committees; Notice of Recruitment of Private-Sector Members

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-17

... range of goods, technologies, and software presently controlled for national security, non-proliferation.... Members of the Committees will not be compensated for their services. The seven TACs are responsible for...

75 FR 62509 - Technical Advisory Committees; Notice of Recruitment of Private-Sector Members

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

... range of goods, technologies, and software presently controlled for national security, non-proliferation.... Members of the Committees will not be compensated for their services. The seven TACs are responsible for...

Administrator Highlights U.S.-Georgian Nuclear Security Cooperation in Tbilisi

ScienceCinema

Thomas D'Agostino

2017-12-09

NNSA Administrator Thomas D'Agostino highlighted the strong U.S.-Georgian cooperation on nuclear security issues during a day-long visit to the Republic of Georgia in mid-June. He briefed the media at availability at the Tbilisi airport. In April 2009, President Obama outlined an ambitious agenda to secure vulnerable nuclear material around the world within four years, calling the danger of a terrorist acquiring nuclear weapons "the most immediate and extreme threat to global security." In this year's State of the Union, he called the threat of nuclear weapons, "the greatest danger to the American people." In order to meet that challenge, the President's FY2011 Budget Request includes close to $2.7 billion for the National Nuclear Security Administration's Defense Nuclear Nonproliferation program -- an increase of 25.7 percent over FY2010. Included in that request is NNSA's Second Line of Defense (SLD) program, which works around the world to strengthen the capability of foreign governments to deter, detect, and interdict illicit trafficking in nuclear and other radioactive materials across international borders and through the global maritime shipping system.

Nuclear thermal source transfer unit, post-blast soil sample drying system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiser, Ralph S.; Valencia, Matthew J

Los Alamos National Laboratory states that its mission is “To solve national security challenges through scientific excellence.” The Science Undergraduate Laboratory Internship (SULI) programs exists to engage undergraduate students in STEM work by providing opportunity to work at DOE facilities. As an undergraduate mechanical engineering intern under the SULI program at Los Alamos during the fall semester of 2016, I had the opportunity to contribute to the mission of the Laboratory while developing skills in a STEM discipline. I worked with Technology Applications, an engineering group that supports non-proliferation, counter terrorism, and emergency response missions. This group specializes in toolmore » design, weapons engineering, rapid prototyping, and mission training. I assisted with two major projects during my appointment Los Alamos. The first was a thermal source transportation unit, intended to safely contain a nuclear thermal source during transit. The second was a soil drying unit for use in nuclear postblast field sample collection. These projects have given me invaluable experience working alongside a team of professional engineers. Skills developed include modeling, simulation, group design, product and system design, and product testing.« less

Multi-Detector Analysis System for Spent Nuclear Fuel Characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reber, Edward Lawrence; Aryaeinejad, Rahmat; Cole, Jerald Donald

1999-09-01

The Spent Nuclear Fuel (SNF) Non-Destructive Analysis (NDA) program at INEEL is developing a system to characterize SNF for fissile mass, radiation source term, and fissile isotopic content. The system is based on the integration of the Fission Assay Tomography System (FATS) and the Gamma-Neutron Analysis Technique (GNAT) developed under programs supported by the DOE Office of Non-proliferation and National Security. Both FATS and GNAT were developed as separate systems to provide information on the location of special nuclear material in weapons configuration (FATS role), and to measure isotopic ratios of fissile material to determine if the material was frommore » a weapon (GNAT role). FATS is capable of not only determining the presence and location of fissile material but also the quantity of fissile material present to within 50%. GNAT determines the ratios of the fissile and fissionable material by coincidence methods that allow the two prompt (immediately) produced fission fragments to be identified. Therefore, from the combination of FATS and GNAT, MDAS is able to measure the fissile material, radiation source term, and fissile isotopics content.« less

Administrator Highlights U.S.-Georgian Nuclear Security Cooperation in Tbilisi

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomas D'Agostino

2010-07-16

NNSA Administrator Thomas D'Agostino highlighted the strong U.S.-Georgian cooperation on nuclear security issues during a day-long visit to the Republic of Georgia in mid-June. He briefed the media at availability at the Tbilisi airport. In April 2009, President Obama outlined an ambitious agenda to secure vulnerable nuclear material around the world within four years, calling the danger of a terrorist acquiring nuclear weapons "the most immediate and extreme threat to global security." In this year's State of the Union, he called the threat of nuclear weapons, "the greatest danger to the American people." In order to meet that challenge, themore » President's FY2011 Budget Request includes close to $2.7 billion for the National Nuclear Security Administration's Defense Nuclear Nonproliferation program -- an increase of 25.7 percent over FY2010. Included in that request is NNSA's Second Line of Defense (SLD) program, which works around the world to strengthen the capability of foreign governments to deter, detect, and interdict illicit trafficking in nuclear and other radioactive materials across international borders and through the global maritime shipping system.« less

31 CFR 515.332 - Information and informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... promote nonproliferation of antiterrorism policies of the United States, including “software” that is not “publicly available” as these terms are defined in 15 CFR parts 779 and 799.1 (1994); or (2) With respect to...

31 CFR 515.332 - Information and informational materials.

Code of Federal Regulations, 2014 CFR

2014-07-01

... promote nonproliferation of antiterrorism policies of the United States, including “software” that is not “publicly available” as these terms are defined in 15 CFR parts 779 and 799.1 (1994); or (2) With respect to...

31 CFR 515.332 - Information and informational materials.

Code of Federal Regulations, 2013 CFR

2013-07-01

... promote nonproliferation of antiterrorism policies of the United States, including “software” that is not “publicly available” as these terms are defined in 15 CFR parts 779 and 799.1 (1994); or (2) With respect to...

31 CFR 515.332 - Information and informational materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... promote nonproliferation of antiterrorism policies of the United States, including “software” that is not “publicly available” as these terms are defined in 15 CFR parts 779 and 799.1 (1994); or (2) With respect to...

31 CFR 515.332 - Information and informational materials.

Code of Federal Regulations, 2011 CFR

2011-07-01

... promote nonproliferation of antiterrorism policies of the United States, including “software” that is not “publicly available” as these terms are defined in 15 CFR parts 779 and 799.1 (1994); or (2) With respect to...

31 CFR 500.332 - Information and informational materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... nonproliferation or antiterrorism policies of the United States, including “software” that is not “publicly available” as these terms are defined in 15 CFR parts 779 and 799.1 (1994); or (2) With respect to which...

NNSA Staff Member Receives NNSA Recognition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Specht, Elaine S.

This article is intended for publication in the NNSA Nonproliferation and International Security (NIS) Highlights, a quarterly newsletter available in print and e-form. It will be published on the NNSA website and is intended for public release.

76 FR 17407 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-29

... United States of America and the Argentine Republic Concerning Peaceful Uses of Nuclear Energy. DATES... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and International Security, Department of Energy. ACTION: Proposed subsequent arrangement. SUMMARY: This notice is...

75 FR 81593 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

... Institute of Nuclear Energy Research, Lungtan, Taiwan. The facility is hereby found acceptable to both... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and International Security, Department of Energy. ACTION: Proposed subsequent arrangement. SUMMARY: Pursuant to...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frye, A.

After decades of diplomatic wrangling, breakthroughs have come on many fronts, both bilateral and multilateral. Not only have Soviets and now Russians joined Americans in agreements to make massive reductions in strategic arms, but the overwhelming majority of nations have signed on to indefinite extension of the Nuclear Nonproliferation Treaty (NPT). Leaders in Ukraine, Kazakstan, and Belarus have greatly contributed to the nonproliferation regime by returning thousands of Soviet nuclear weapons to Russia for safekeeping and elimination, a process to be completed this fall with the departure of the last few warheads from Belarus. The Conventional Forces in Europe Treatymore » has ratified and reinforced the transformation of the military balance on the continent, although the altered political landscape after the collapse of the Soviet empire will require nettlesome changes in its provisions. The long-sought Chemical Weapons Convention should enter into force shortly, and, despite India`s recalcitrance, a comprehensive nuclear test ban enjoys nearly universal support.« less

Nuclear proliferation-resistance and safeguards for future nuclear fuel cycle

NASA Astrophysics Data System (ADS)

Kuno, Y.; Inoue, N.; Senzaki, M.

2009-03-01

Corresponding to the world nuclear security concerns, future nuclear fuel cycle (NFC) should have high proliferation-resistance (PR) and physical protection (PP), while promotion of the peaceful use of the nuclear energy must not be inhibited. In order to accomplish nuclear non-proliferation from NFC, a few models of the well-PR systems should be developed so that international community can recognize them as worldwide norms. To find a good balance of 'safeguard-ability (so-called extrinsic measure or institutional barrier)' and 'impede-ability (intrinsic feature or technical barrier)' will come to be essential for NFC designers to optimize civilian nuclear technology with nuclear non-proliferation, although the advanced safeguards with high detectability can still play a dominant role for PR in the states complying with full institutional controls. Accomplishment of such goal in a good economic efficiency is a future key challenge.

Stabilization and immobilization of military plutonium: A non-proliferation perspective

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leventhal, P.

1996-05-01

The Nuclear Control Institute welcomes this DOE-sponsored technical workshop on stabilization and immobilization of weapons plutonium (W Pu) because of the significant contribution it can make toward the ultimate non-proliferation objective of eliminating weapons-usable nuclear material, plutonium and highly enriched uranium (HEU), from world commerce. The risk of theft or diversion of these materials warrants concern, as only a few kilograms in the hands of terrorists or threshold states would give them the capability to build nuclear weapons. Military plutonium disposition questions cannot be addressed in isolation from civilian plutonium issues. The National Academy of Sciences has urged that {open_quotes}furthermore » steps should be taken to reduce the proliferation risks posed by all of the world`s plutonium stocks, military and civilian, separated and unseparated...{close_quotes}. This report discusses vitrification and a mixed oxide fuels option, and the effects of disposition choices on civilian plutonium fuel cycles.« less

Neutronics calculations on the impact of burnable poisons to safety and non-proliferation aspects of inert matrix fuel

NASA Astrophysics Data System (ADS)

Pistner, C.; Liebert, W.; Fujara, F.

2006-06-01

Inert matrix fuels (IMF) with plutonium may play a significant role to dispose of stockpiles of separated plutonium from military or civilian origin. For reasons of reactivity control of such fuels, burnable poisons (BP) will have to be used. The impact of different possible BP candidates (B, Eu, Er and Gd) on the achievable burnup as well as on safety and non-proliferation aspects of IMF are analyzed. To this end, cell burnup calculations have been performed and burnup dependent reactivity coefficients (boron worth, fuel temperature and moderator void coefficient) were calculated. All BP candidates were analyzed for one initial BP concentration and a range of different initial plutonium-concentrations (0.4-1.0 g cm-3) for reactor-grade plutonium isotopic composition as well as for weapon-grade plutonium. For the two most promising BP candidates (Er and Gd), a range of different BP concentrations was investigated to study the impact of BP concentration on fuel burnup. A set of reference fuels was identified to compare the performance of uranium-fuels, MOX and IMF with respect to (1) the fraction of initial plutonium being burned, (2) the remaining absolute plutonium concentration in the spent fuel and (3) the shift in the isotopic composition of the remaining plutonium leading to differences in the heat and neutron rate produced. In the case of IMF, the remaining Pu in spent fuel is unattractive for a would be proliferator. This underlines the attractiveness of an IMF approach for disposal of Pu from a non-proliferation perspective.

Laboratory directed research and development fy1999 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Ayat, R A

2000-04-11

The Lawrence Livermore National Laboratory (LLNL) was founded in 1952 and has been managed since its inception by the University of California (UC) for the U.S. Department of Energy (DOE). Because of this long association with UC, the Laboratory has been able to recruit a world-class workforce, establish an atmosphere of intellectual freedom and innovation, and achieve recognition in relevant fields of knowledge as a scientific and technological leader. This environment and reputation are essential for sustained scientific and technical excellence. As a DOE national laboratory with about 7,000 employees, LLNL has an essential and compelling primary mission to ensuremore » that the nation's nuclear weapons remain safe, secure, and reliable and to prevent the spread and use of nuclear weapons worldwide. The Laboratory receives funding from the DOE Assistant Secretary for Defense Programs, whose focus is stewardship of our nuclear weapons stockpile. Funding is also provided by the Deputy Administrator for Defense Nuclear Nonproliferation, many Department of Defense sponsors, other federal agencies, and the private sector. As a multidisciplinary laboratory, LLNL has applied its considerable skills in high-performance computing, advanced engineering, and the management of large research and development projects to become the science and technology leader in those areas of its mission responsibility. The Laboratory Directed Research and Development (LDRD) Program was authorized by the U.S. Congress in 1984. The Program allows the Director of each DOE laboratory to fund advanced, creative, and innovative research and development (R&D) activities that will ensure scientific and technical vitality in the continually evolving mission areas at DOE and the Laboratory. In addition, the LDRD Program provides LLNL with the flexibility to nurture and enrich essential scientific and technical competencies, which attract the most qualified scientists and engineers. The LDRD Program also enables many collaborations with the scientific community in academia, national and international laboratories, and industry. The projects in the FY1999 LDRD portfolio were carefully selected to continue vigorous support of the strategic vision and the long-term goals of DOE and the Laboratory. Projects chosen for LDRD funding undergo stringent selection processes, which look for high-potential scientific return, emphasize strategic relevance, and feature technical peer reviews by external and internal experts. The FY1999 projects described in this annual report focus on supporting the Laboratory's national security needs: stewardship of the U.S. nuclear weapons stockpile, responsibility for the counter- and nonproliferation of weapons of mass destruction, development of high-performance computing, and support of DOE environmental research and waste management programs. In the past, LDRD investments have significantly enhanced LLNL scientific capabilities and greatly contributed to the Laboratory's ability to meet its national security programmatic requirements. Examples of past investments include technical precursors to the Accelerated Strategic Computing Initiative (ASCI), special-materials processing and characterization, and biodefense. Our analysis of the FY1999 portfolio shows that it strongly supports the Laboratory's national security mission. About 95% of the LDRD dollars have directly supported LLNL's national security activities in FY1999, which far exceeds the portion of LLNL's overall budget supported by National Security Programs, which is 63% for FY1999.« less

70 Years of Making the World Safer: Extended

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Extended version with narration. This video shows our roles in making the world safer — working to end World War II, providing stable isotopes for research, providing unique precision manufacturing capabilities, and meeting nonproliferation and global security missions.

Sandia National Laboratories Strategic Context Workshop Series 2017: National Security Futures for Strategic Thinking.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keller, Elizabeth James Kistin; Roll, Elizabeth; Aamir, Munaf Syed

In August 2017, Sandia convened five workshops to explore the future of advanced technologies and global peace and security through the lenses of deterrence, information, innovation, nonproliferation, and population and Earth systems.

75 FR 82005 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-29

... Cooperation Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and International Security, Department of Energy. ACTION: Proposed subsequent arrangement. SUMMARY: This notice is...

76 FR 30326 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

... International Security, National Nuclear Security Administration, Department of Energy. ACTION: Proposed... United States of America and the Government of Japan Concerning Peaceful Uses of Nuclear Energy. DATES... Energy. Anne M. Harrington, Deputy Administrator, Defense Nuclear Nonproliferation. [FR Doc. 2011-12919...

A Non-Proliferating Fuel Cycle: No Enrichment, Reprocessing or Accessible Spent Fuel - 12375

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parker, Frank L.

2012-07-01

Current fuel cycles offer a number of opportunities for access to plutonium, opportunities to create highly enriched uranium and access highly radioactive wastes to create nuclear weapons and 'dirty' bombs. The non-proliferating fuel cycle however eliminates or reduces such opportunities and access by eliminating the mining, milling and enrichment of uranium. The non-proliferating fuel cycle also reduces the production of plutonium per unit of energy created, eliminates reprocessing and the separation of plutonium from the spent fuel and the creation of a stream of high-level waste. It further simplifies the search for land based deep geologic repositories and interim storagemore » sites for spent fuel in the USA by disposing of the spent fuel in deep sub-seabed sediments after storing the spent fuel at U.S. Navy Nuclear Shipyards that have the space and all of the necessary equipment and security already in place. The non-proliferating fuel cycle also reduces transportation risks by utilizing barges for the collection of spent fuel and transport to the Navy shipyards and specially designed ships to take the spent fuel to designated disposal sites at sea and to dispose of them there in deep sub-seabed sediments. Disposal in the sub-seabed sediments practically eliminates human intrusion. Potential disposal sites include Great Meteor East and Southern Nares Abyssal Plain. Such sites then could easily become international disposal sites since they occur in the open ocean. It also reduces the level of human exposure in case of failure because of the large physical and chemical dilution and the elimination of a major pathway to man-seawater is not potable. Of course, the recovery of uranium from sea water and the disposal of spent fuel in sub-seabed sediments must be proven on an industrial scale. All other technologies are already operating on an industrial scale. If externalities, such as reduced terrorist threats, environmental damage (including embedded emissions), long term care, reduced access to 'dirty' bomb materials, the social and political costs of siting new facilities and the psychological impact of no solution to the nuclear waste problem, were taken into account, the costs would be far lower than those of the present fuel cycle. (authors)« less

United States and Russian Cooperation on Issues of Nuclear Nonproliferation

DTIC Science & Technology

2005-06-01

Reactors ( RERTR ) This project works with Russia to facilitate conversion of its research and test reactors from highly enriched uranium (HEU) fuel...reactor fuel purchase, accelerated RERTR activities, and accelerated Material Conversion and Consolidation implementation. 89 j. Fissile Materials

Iran, North Korea, and Syria Nonproliferation Reform and Modernization Act of 2011

THOMAS, 112th Congress

Rep. Ros-Lehtinen, Ileana [R-FL-18

2011-06-03

Senate - 12/14/2011 Received in the Senate and Read twice and referred to the Committee on Foreign Relations. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

A resolution commemorating the 40th anniversary of the Treaty on the Non-Proliferation of Nuclear Weapons.

THOMAS, 111th Congress

Sen. Casey, Robert P., Jr. [D-PA

2010-03-08

Senate - 04/13/2010 Placed on Senate Legislative Calendar under General Orders. Calendar No. 345. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

78 FR 52170 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

... Agreement for Cooperation Concerning Civil Uses of Nuclear Energy Between the Government of the United... States of America and the Government of Japan Concerning Peaceful Uses of Nuclear Energy. DATES: This... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and...

78 FR 40131 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... Concerning Peaceful Uses of Nuclear Energy and the Agreement Between the Government of the United States of America and Australia Concerning Peaceful Uses of Nuclear Energy. DATES: This subsequent arrangement will... Nonproliferation and International Security, National Nuclear Security Administration, Department of Energy...

77 FR 35366 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... Uses of Nuclear Energy and the Agreement for Cooperation Between the United States of America and the Republic of Kazakhstan Concerning Peaceful Uses of Nuclear Energy. DATES: This subsequent arrangement will... Nonproliferation and International Security, National Nuclear Security Administration, Department of Energy...

76 FR 17407 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-29

... United States of America and the Argentine Republic Concerning Peaceful Uses of Nuclear Energy. DATES... originally obtained by KAERI from U.S. Department of Energy's National Nuclear Security Administration Y-12... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and...

76 FR 2892 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-18

... Peaceful Uses of Nuclear Energy and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy... Energy. Thomas P. D'Agostino, Administrator, National Nuclear Security Administration. [FR Doc. 2011-905... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and...

Neutron and Gamma Imaging for National Security Applications

NASA Astrophysics Data System (ADS)

Hornback, Donald

2017-09-01

The Department of Energy, National Nuclear Security Administration (NNSA), Office of Defense Nuclear Nonproliferation Research and Development (DNN R&D/NA-22) possesses, in part, the mission to develop technologies in support of nuclear security efforts in coordination with other U.S. government entities, such as the Department of Defense and the Department of Homeland Security. DNN R&D has long supported research in nuclear detection at national labs, universities, and through the small business innovation research (SBIR) program. Research topics supported include advanced detector materials and electronics, detection algorithm development, and advanced gamma/neutron detection systems. Neutron and gamma imaging, defined as the directional detection of radiation as opposed to radiography, provides advanced detection capabilities for the NNSA mission in areas of emergency response, international safeguards, and nuclear arms control treaty monitoring and verification. A technical and programmatic overview of efforts in this field of research will be summarized.

Lessons of the North Korean crisis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazarr, M.J.

1993-07-01

The crisis involving North Korea`s suspected nuclear weapon program is over, at least for now. Pyongyang has agreed to suspend its decision to withdraw from the nuclear Non-Proliferation Treaty (NPT) and to assume its obligations allowing continued International Atomic Energy Agency (IAEA) inspections of its nuclear facilities, although it has yet to accept IAEA {open_quotes}special{close_quotes} inspections of suspect nuclear sites. In exchange, North Korea obtained a few specific commitments from the United States - nuclear non-aggression, for example - as well as hints of longer-term benefits such as high-level US-North Korean talks extending to other topics, the cancellation of themore » US-South Korean {open_quotes}Team Spirit{close_quotes} military exercise, the right to reciprocal inspections in South Korea and an influx of South Korean and Japanese investment, provided North Korea meets its obligations under the NPT.« less

Walk the Talk: Progress in Building a Supply Chain Security Culture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hund, Gretchen

Pacific Northwest National Laboratory (PNNL) has engaged industry to “go beyond compliance” for over a decade in controlling and securing their supply chains to ensure their goods are not diverted to nuclear weapons programs. This work has focused on dual-use industries that manufacture products that can be used in both commercial applications and in the development of a nuclear weapon. The team encourages industry to self-regulate to reduce proliferation risks. As part of that work, PNNL interviewed numerous companies about their compliance practices to understand their business and to build awareness around best practices to ensure security of goods, technology,more » and information along their supply chains. From conducting this work, PNNL identified indicators that a company can adopt as part of its commitment to nonproliferation ideals with a focus on supply chain security.« less

High-Temperature Oxidation of Plutonium Surrogate Metals and Alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sparks, Joshua C.; Krantz, Kelsie E.; Christian, Jonathan H.

The Plutonium Management and Disposition Agreement (PMDA) is a nuclear non-proliferation agreement designed to remove 34 tons of weapons-grade plutonium from Russia and the United States. While several removal options have been proposed since the agreement was first signed in 2000, processing the weapons-grade plutonium to mixed-oxide (MOX) fuel has remained the leading candidate for achieving the goals of the PMDA. However, the MOX program has received its share of criticisms, which causes its future to be uncertain. One alternative pathway for plutonium disposition would involve oxidizing the metal followed by impurity down blending and burial in the Waste Isolationmore » Pilot Plant (WIPP) in Carlsbad, New Mexico. This pathway was investigated by use of a hybrid microwave and a muffle furnace with Fe and Al as surrogate materials. Oxidation occurred similarly in the microwave and muffle furnace; however, the microwave process time was significantly faster.« less

NGSPN @ BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pepper, S. E.; Bachner, K.; Gomera, J.

Brookhaven National Laboratory’s (BNL’s) Nonproliferation and National Security Department hosted the Next Generation Safeguards Professional Network (NGSPN) at BNL September 6-9, 2016. Thirteen representatives from seven Department of Energy National Laboratories, including two from BNL, participated in the four-day meeting. The NGSPN meeting was sponsored by the Office of International Nuclear Safeguards (NA-241) of the National Nuclear Security Administration, which provided funding for BNL’s development and conduct of the meeting program and the participant’s labor and travel. NGSPN meetings were previously held at Savannah River National Laboratory, Oak Ridge National Laboratory, Idaho National Laboratory, Sandia National Laboratories, and Los Alamosmore » National Laboratory. The purpose of NGSPN is to provide a forum for early-career international safeguards practitioners to network with their peers, to meet international safeguards experts from other institutions and to learn about organizations other than their employers who contribute to international safeguards.« less

Getting Ready for a Nuclear-Ready Iran

DTIC Science & Technology

2005-10-01

College’s Strategic Studies Institute. The Nonproliferation Policy Education Center (NPEC) has worked closely with Dr. Douglas Lovelace , Ms. Marianne...essays and of NPEC’s Deputy Executive Director, Amanda Sokolski, my wife; and our assistant, Mohammad Nasseri-Asl, in pulling it all together. Without

76 FR 80305 - Amendment to the International Traffic in Arms Regulations: Revision of U.S. Munitions List...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-23

... the Atomic Energy Act of 1954, as amended, and the Nuclear Non- Proliferation Act of 1978, as amended... the Nuclear Non-Proliferation Act of 1978, as amended. Dated: December 16, 2011. Ellen O. Tauscher...

Teaching Activities on Horizontal Nuclear Proliferation.

ERIC Educational Resources Information Center

Zola, John

1990-01-01

Provides learning activities concerning the horizontal proliferation of nuclear weapons. Includes step-by-step directions for four activities: (1) the life cycle of nuclear weapons; (2) nuclear nonproliferation: pros and cons; (3) the nuclear power/nuclear weapons connection; and (4) managing nuclear proliferation. (NL)

78 FR 40132 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy Between the... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and...

78 FR 40131 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy Between the... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and...

78 FR 40735 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-08

... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy Between the... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and...

75 FR 67087 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-01

... Cooperation Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy... DEPARTMENT OF ENERGY Proposed Subsequent Arrangement AGENCY: Office of Nonproliferation and...

10 CFR 1045.13 - Classification prohibitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Classification prohibitions. 1045.13 Section 1045.13... Identification of Restricted Data and Formerly Restricted Data Information § 1045.13 Classification prohibitions... national security or nonproliferation reasons; (e) Unduly restrict dissemination by assigning an improper...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peterson, J.F.

The global proliferation of ballistic missiles and weapons of mass destruction (WMD) has become one of the most immediate and dangerous threats to U.S. national security. Ballistic missiles were used in four of the last six major wars. Some 190 missiles were fired by Iraqis over a six week period at Iranian cities in 1988, during the 'War of the Cities'. Iraq's firing of Scuds against coalition forces and Israel during the Gulf War provided a vivid reminder of the threat these weapons can present to the world community. During the 1980's, many Third World countries assigned a high prioritymore » to the acquisition of ballistic missiles. By 1991, more than 20 of these nations either possessed ballistic missiles or were attempting to obtain them. Today 43 nations possess ballistic missiles. Seventeen of these probably have a nuclear weapon capability, with 20 of them possessing also a chemical or biological capability. This paper seeks to: define the military challenge ballistic missiles represent; review current U.S. counter-proliferation and nonproliferation initiatives and, finally make recommendations on other potential methods or considerations to reduce ballistic missile proliferation.« less

The physics of solid-state neutron detector materials and geometries.

PubMed

Caruso, A N

2010-11-10

Detection of neutrons, at high total efficiency, with greater resolution in kinetic energy, time and/or real-space position, is fundamental to the advance of subfields within nuclear medicine, high-energy physics, non-proliferation of special nuclear materials, astrophysics, structural biology and chemistry, magnetism and nuclear energy. Clever indirect-conversion geometries, interaction/transport calculations and modern processing methods for silicon and gallium arsenide allow for the realization of moderate- to high-efficiency neutron detectors as a result of low defect concentrations, tuned reaction product ranges, enhanced effective omnidirectional cross sections and reduced electron-hole pair recombination from more physically abrupt and electronically engineered interfaces. Conversely, semiconductors with high neutron cross sections and unique transduction mechanisms capable of achieving very high total efficiency are gaining greater recognition despite the relative immaturity of their growth, lithographic processing and electronic structure understanding. This review focuses on advances and challenges in charged-particle-based device geometries, materials and associated mechanisms for direct and indirect transduction of thermal to fast neutrons within the context of application. Calorimetry- and radioluminescence-based intermediate processes in the solid state are not included.

New Horizons and New Strategies in Arms Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, J. editor

In the last ten years, since the break-up of the Soviet Union, remarkable progress in arms control and disarmament has occurred. The Nuclear Non-Proliferation Treaty (NPT), the completion of the Comprehensive Test Ban Treaty (CTBT), and the Chemical Weapons Treaty (CWC) are indicative of the great strides made in the non- proliferation arena. Simultaneously, the Intermediate Nuclear Forces Treaty (INF), the Conventional Forces Treaty in Europe (CFE), and the Strategic Arms Reduction Treaties (START), all associated with US-Soviet Union (now Russia) relations have assisted in redefining European relations and the security landscape. Finally, it now appears that progress is inmore » the offing in developing enhanced compliance measures for the Biological and Toxin Weapons Convention (BTWC). In sum, all of these achievements have set the stage for the next round of arms control activities, which may lead to a much broader, and perhaps more diffused multilateral agenda. In this new and somewhat unpredictable international setting, arms control and disarmament issues will require solutions that are both more creative and innovative than heretofore.« less

Deterring Nuclear Proliferation: The Importance of IAEA Safeguards: A TEXTBOOK

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenthal, M.D.; Fishbone, L.G.; Gallini, L.

2012-03-13

Nuclear terrorism and nuclear proliferation are among the most pressing challenges to international peace and security that we face today. Iran and Syria remain in non-compliance with the safeguards requirements of the NPT, and the nuclear ambitions of North Korea remain unchecked. Despite these challenges, the NPT remains a cornerstone of the nuclear non-proliferation regime, and the safeguards implemented by the International Atomic Energy Agency (IAEA) under the NPT play a critical role in deterring nuclear proliferation.How do they work? Where did they come from? And what is their future? This book answers these questions. Anyone studying the field ofmore » nuclear non-proliferation will benefit from reading this book, and for anyone entering the field, the book will enable them to get a running start. Part I describes the foundations of the international safeguards system: its origins in the 1930s - when new discoveries in physics made it clear immediately that nuclear energy held both peril and promise - through the entry into force in 1970 of the NPT, which codified the role of IAEA safeguards as a means to verify states NPT commitments not to acquire nuclear weapons. Part II describes the NPT safeguards system, which is based on a model safeguards agreement developed specifically for the NPT, The Structure and Content of Agreements between the Agency and States required in connection with the Treaty on the Non-Proliferation of Nuclear Weapons, which has been published by the IAEA as INFCIRC/153. Part III describes events, especially in South Africa, the DPRK, and Iraq in the early 1990s, that triggered a transformation in the way in which safeguards were conceptualized and implemented.« less

Application of neuro-fuzzy methods to gamma spectroscopy

NASA Astrophysics Data System (ADS)

Grelle, Austin L.

Nuclear non-proliferation activities are an essential part of national security activities both domestic and abroad. The safety of the public in densely populated environments such as urban areas or large events can be compromised if devices using special nuclear materials are present. Therefore, the prompt and accurate detection of these materials is an important topic of research, in which the identification of normal conditions is also of importance. With gamma-ray spectroscopy, these conditions are identified as the radiation background, which though being affected by a multitude of factors is ever present. Therefore, in nuclear non-proliferation activities the accurate identification of background is important. With this in mind, a method has been developed to utilize aggregate background data to predict the background of a location through the use of an Artificial Neural Network (ANN). After being trained on background data, the ANN is presented with nearby relevant gamma-ray spectroscopy data---as identified by a Fuzzy Inference System - to create a predicted background spectra to compare to a measured spectra. If a significant deviation exists between the predicted and measured data, the method alerts the user such that a more thorough investigation can take place. Research herein focused on data from an urban setting in which the number of false positives was observed to be 28 out of a total of 987, representing 2.94% error. The method therefore currently shows a high rate of false positives given the current configuration, however there are promising steps that can be taken to further minimize this error. With this in mind, the method stands as a potentially significant tool in urban nuclear nonproliferation activities.

SIGNATURES OF ILLICIT NUCLEAR PROCUREMENT NETWORKS: AN OVERVIEW OF PRELIMINARY APPROACHES AND RESULTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Webster, Jennifer B.; Erikson, Luke E.; Gastelum, Zoe N.

2014-05-12

The illicit trafficking of strategic nuclear commodities (defined here as the goods needed for a covert nuclear program excluding special nuclear materials) poses a significant challenge to the international nuclear nonproliferation community. Export control regulations, both domestically and internationally, seek to inhibit the spread of strategic nuclear commodities by restricting their sale to parties that may use them for nefarious purposes. However, export controls alone are not sufficient for preventing the illicit transfer of strategic nuclear goods. There are two major pitfalls to relying solely on export control regulations for the deterrence of proliferation of strategic goods. First, export controlmore » enforcement today relies heavily on the honesty and willingness of participants to adhere to the legal framework already in place. Secondly, current practices focus on the evaluation of single records which allow for the necessary goods to be purchased separately and hidden within the thousands of legitimate commerce transactions that occur each day, disregarding strategic information regarding several purchases. Our research presents two preliminary data-centric approaches for investigating procurement networks of strategic nuclear commodities. Pacific Northwest National Laboratory (PNNL) has been putting significant effort into nonproliferation activities as an institution, both in terms of the classical nuclear material focused approach and in the examination of other strategic goods necessary to implement a nuclear program. In particular, the PNNL Signature Discovery Initiative (SDI) has codified several scientific methodologies for the detection, characterization, and prediction of signatures that are indicative of a phenomenon of interest. The methodologies and tools developed under SDI have already been applied successfully to problems in bio-forensics, cyber security and power grid balancing efforts and they have now made the nonproliferation of strategic goods into a challenge problem for testing their methodology and tools. As a first step towards the detection and characterization of illicit procurement networks, our research examines procurement networks as defined by a system of entities (people or companies) that enter into transactions of specific items with one another. Once we have defined such networks, we are interested in answering questions about the behavior and characterization of such networks. The questions we wish to answer regarding procurement networks are, first, “Can we detect networks within large, noisy datasets?” and second, “To what extent can we compare multiple networks and identify their similarities?” As procurement networks can be naturally viewed as a graph, we have employed several graph analytic tools to aid in these tasks. In particular, Graphscape, an SDI tool, uses a novel method to approximate edit distance, a graph distance measure based on the number of changes needed to transform one graph into another, in order to measure how similar two given graphs are to each other. Given a set of graphs where vertices represent companies and edges represent a shipment from company A to company B, we can calculate an all-for-all comparison of graphs. In this way, we are able to determine which graphs are most similar, and which require more changes to transform one into the other. The set of graphs to be compared can be further specialized to provide more insight, e.g., using different time periods to explore events in a company life cycle.« less

10 CFR 110.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... that are subject to the nuclear non-proliferation export licensing controls of the Department of... group of nations concluded under section 123 of the Atomic Energy Act, as amended. Atomic Energy Act... that may be used in nuclear or non-nuclear applications. Effective kilograms of special nuclear...

Application of the Terrestar Satellite Constellation to the Global Initiative for Tracking Special and Nonproliferation Material

DTIC Science & Technology

2011-09-01

A.  EXPERIMENT BACKGROUND ................................................................35  1.  BlackBerry Messenger...in Orbit (From [Terrestar, 2011])..................................................24  Figure 11.  BlackBerry Tag...36  Figure 12.  OV-1 Diagram of BlackBerry Tag

41 CFR 109-1.5302 - Policies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... nonproliferation objectives of the Government which must be evaluated. Organizations will identify high risk... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Policies. 109-1.5302 Section 109-1.5302 Public Contracts and Property Management Federal Property Management Regulations System...

10 CFR 810.4 - Communications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Communications. 810.4 Section 810.4 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.4 Communications. (a) All communications... and Nonproliferation. Telephone: (202) 586-2331. (b) Communications also may be delivered to the...

10 CFR 810.4 - Communications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Communications. 810.4 Section 810.4 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.4 Communications. (a) All communications... and Nonproliferation. Telephone: (202) 586-2331. (b) Communications also may be delivered to the...

31 CFR 800.209 - Critical technologies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Critical technologies. 800.209 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.209 Critical technologies. The term critical technologies..., nuclear nonproliferation, or missile technology), as well as those that are controlled for reasons of...

31 CFR 800.209 - Critical technologies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Critical technologies. 800.209 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.209 Critical technologies. The term critical technologies..., nuclear nonproliferation, or missile technology), as well as those that are controlled for reasons of...

31 CFR 800.209 - Critical technologies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Critical technologies. 800.209 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.209 Critical technologies. The term critical technologies..., nuclear nonproliferation, or missile technology), as well as those that are controlled for reasons of...

31 CFR 800.209 - Critical technologies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Critical technologies. 800.209 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.209 Critical technologies. The term critical technologies..., nuclear nonproliferation, or missile technology), as well as those that are controlled for reasons of...

10 CFR 810.4 - Communications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Communications. 810.4 Section 810.4 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.4 Communications. (a) All communications... and Nonproliferation. Telephone: (202) 586-2331. (b) Communications also may be delivered to the...

76 FR 17406 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-29

... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy Between the... Energy. Anne M. Harrington, Deputy Administrator, Defense Nuclear Nonproliferation. [FR Doc. 2011-7330...

77 FR 53876 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy Between the... the Department of Energy. Anne M. Harrington, Deputy Administrator, Defense Nuclear Nonproliferation...

77 FR 53876 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy Between the... Energy. Anne M. Harrington, Deputy Administrator, Defense Nuclear Nonproliferation. [FR Doc. 2012-21686...

77 FR 53876 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the Government of Canada and the Agreement for Cooperation in the Peaceful Uses of Nuclear Energy Between the... Department of Energy. Anne M. Harrington, Deputy Administrator, Defense Nuclear Nonproliferation. [FR Doc...

Uranium and Thorium

ERIC Educational Resources Information Center

Finch, Warren I.

1978-01-01

The results of President Carter's policy on non-proliferation of nuclear weapons are expected to slow the growth rate in energy consumption, put the development of the breeder reactor in question, halt plans to reprocess and recycle uranium and plutonium, and expand facilities to supply enriched uranium. (Author/MA)

Precision Information Environment (PIE) for International Safeguards: Pre-Demonstration Development Use Cases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gastelum, Zoe N.; Henry, Michael J.

2013-11-13

In FY2013, the PIE International Safeguards team demonstrated our development progress to U.S. Department of Energy (DOE) staff from the Office of Nonproliferation and International Security (NA-24, our client) and the Office of Defense Nuclear Nonproliferation Research and Development (NA-22). Following the demonstration, the team was asked by our client to complete additional development prior to a planned demonstration at the International Atomic Energy Agency (IAEA), scheduled tentatively for January or spring of 2014. The team discussed four potential areas for development (in priority order), and will develop them as time and funding permit prior to an IAEA demonstration. Themore » four capability areas are: 1. Addition of equipment manuals to PIE-accessible files 2. Optical character recognition (OCR) of photographed text 3. Barcode reader with information look-up from a database 4. Add Facilities to Data Model 5. Geospatial capabilities with information integration Each area will be described below in a use case.« less

Assessment of Gamma-Ray-Spectra Analysis Method Utilizing the Fireworks Algorithm for Various Error Measures

DOE PAGES

Alamaniotis, Miltiadis; Tsoukalas, Lefteri H.

2018-01-01

The analysis of measured data plays a significant role in enhancing nuclear nonproliferation mainly by inferring the presence of patterns associated with special nuclear materials. Among various types of measurements, gamma-ray spectra is the widest utilized type of data in nonproliferation applications. In this paper, a method that employs the fireworks algorithm (FWA) for analyzing gamma-ray spectra aiming at detecting gamma signatures is presented. In particular, FWA is utilized to fit a set of known signatures to a measured spectrum by optimizing an objective function, where non-zero coefficients express the detected signatures. FWA is tested on a set of experimentallymore » obtained measurements optimizing various objective functions—MSE, RMSE, Theil-2, MAE, MAPE, MAP—with results exhibiting its potential in providing highly accurate and precise signature detection. Finally and furthermore, FWA is benchmarked against genetic algorithms and multiple linear regression, showing its superiority over those algorithms regarding precision with respect to MAE, MAPE, and MAP measures.« less

An Important Issue: Non-Proliferation of Nuclear Weapons

NASA Astrophysics Data System (ADS)

Castellano, Doc

2001-03-01

Historic Facts and Philosophy: In August, 1947, I participated in a secret meeting concerning the validity and use of a hydrogen bomb. I vigorously supported a ``Super Manhattan Project" to build an ``H" bomb. My philosophy at the time was `bigger and better,' to ensure that no nation attacked the U.S. Our retaliation with ``H" bombs vs. ``A" bombs would be too overwhelming for any nation to risk attacking us should they obtain their own ``A" bombs. Thus, all nations would be forced to use diplomacy. I am older and wiser, and am now convinced that World Test Ban Treaties, non-proliferation of nuclear weapons, and space free of any military weapons is the best policy for all nations and humanity. With current nuclear testing at nearby Yucca Flats, Nevada, Vandenberg AF/Missile site, Cal Tech, etc., I therefore propose that our new APS California Division form a three-person committee to tabulate all pertinent data and submit it to a qualified expert for review and further action. Comments and suggestions are invited.

An Iranium bomb?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Albright, D.

1995-07-01

This year, the nuclear proliferation spotlight has swung away from Iraq and North Korea, only to focus on Iran. Western intelligence agencies have assembled a substantial body of evidence suggesting that, although Iran signed the Nuclear Non-Proliferation Treaty (NPT), it is secretly pursuing a broad, organized effort to develop nuclear weapons. US officials say that Iran is attempting to acquire nuclear technologies that are not consistent with a strictly peaceful program. Intelligence agencies have detected procurement patterns that point to a weapons program. Iran has a multifaceted strategy to develop options to make nuclear weapons: Iran has sought, with limitedmore » success, to buy nuclear power and research facilities from many countries, particularly China and Russia; Iran has shopped quietly in many countries, particularly in Western and Eastern Europe, for a wide range of nuclear-related or dual-use nuclear items that might enable it to put together facilities to enrich uranium, separate plutonium, and make nuclear weapons. There is little public information about how effective this clandestine shopping has been or which countries have been contacted; There is no evidence that Iran has bought any fissile material - but not for wont of trying, and the matter continues to be scrutinized very closely.« less

Is It Time To Consider Global Sharing of Integral Physics Data?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harold F. McFarlane

The innocent days of the Atoms for Peace program vanished with the suicide attack on the World Trade Center in New York City that occurred while the GLOBAL 2001 international nuclear fuel cycle conference was convened in Paris. Today’s reality is that maintaining an inventory of unirradiated highly enriched uranium or plutonium for critical experiments requires a facility to accept substantial security cost and intrusion. In the context of a large collection of benchmark integral experiments collected over several decades and the ongoing rapid advances in computer modeling and simulation, there seems to be ample incentive to reduce both themore » number of facilities and material inventory quantities worldwide. As a result of ongoing nonproliferation initiatives, there are viable programs that will accept highly enriched uranium for down blending into commercial fuel. Nevertheless, there are formidable hurdles to overcome before national institutions will voluntarily give up existing nuclear research capabilities. GLOBAL 2005 was the appropriate forum to begin fostering a new spirit of cooperation that could lead to improved international security and better use of precious research and development resources, while ensuring access to existing and future critical experiment data.« less

Sandia National Laboratories: Facts & Figures

Science.gov Websites

Technology Partnerships Business, Industry, & Non-Profits Government Universities Center for Development Agreement (CRADA) Strategic Partnership Projects, Non-Federal Entity (SPP/NFE) Agreements New 1,615.2 Defense Nuclear Nonproliferation 204.2 Other NNSA 1.2 NON-NNSA DOE 2,061.1M Energy & Threat

10 CFR 110.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... commodities on the Commerce Control List that are subject to the nuclear non-proliferation export licensing... group of nations concluded under section 123 of the Atomic Energy Act. Atomic Energy Act means the... surrounding environment. Dual-use means equipment and materials that may be used in nuclear or non-nuclear...

10 CFR 110.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... commodities on the Commerce Control List that are subject to the nuclear non-proliferation export licensing... group of nations concluded under section 123 of the Atomic Energy Act. Atomic Energy Act means the... surrounding environment. Dual-use means equipment and materials that may be used in nuclear or non-nuclear...

10 CFR 110.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... commodities on the Commerce Control List that are subject to the nuclear non-proliferation export licensing... group of nations concluded under section 123 of the Atomic Energy Act. Atomic Energy Act means the... surrounding environment. Dual-use means equipment and materials that may be used in nuclear or non-nuclear...

10 CFR 110.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... commodities on the Commerce Control List that are subject to the nuclear non-proliferation export licensing... group of nations concluded under section 123 of the Atomic Energy Act. Atomic Energy Act means the... surrounding environment. Dual-use means equipment and materials that may be used in nuclear or non-nuclear...

78 FR 42584 - Bureau of International Security and Nonproliferation: Report to Congress Pursuant to Section...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-16

...-finished metals such as aluminum and steel, coal, and software for integrating industrial processes. We...; boron; cobalt; copper; copper infiltrated tungsten; copper- beryllium; graphite; hastelloy; inconel; magnesium; molybdenum; nickel; niobium; silver infiltrated tungsten; steels (including, but not limited to...

Post Cold War Nuclear Weapons Policy

DTIC Science & Technology

2012-03-20

are unknown.”14 This instability threatens the success and future of the NPT. According to scholar Joseph F. Pilat , While the vision of a nuclear...for the Study of Weapons of Mass Destruction, April 2007. 15 Joseph F. Pilat , “Nonproliferation, Arms Control and Disarmament, and ExtendedDeterrence

Resource Letter PSNAC-1: Physics and society: Nuclear arms control

NASA Astrophysics Data System (ADS)

Glaser, Alexander; Mian, Zia

2008-01-01

This Resource Letter provides a guide to the literature on nuclear arms control for the nonspecialist. Journal articles and books are cited for the following topics: nuclear weapons, fissile materials, nonproliferation, missiles and missile defenses, verification, disarmament, and the role of scientists in arms control.

Developments in Assisting Countries in Implementing the IAEA Additional Protocol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Killinger, Mark H.; Hansen, Linda H.; Cain, Ronald A.

In 2008, the U.S. Department of Energy (DOE) began assisting selected non-nuclear weapon states in planning and preparing for implementation of the International Atomic Energy Agency’s Additional Protocol (AP). Since then, the AP international implementation program has contributed to the substantial progress made by Vietnam, Thailand, Iraq, and Malaysia in preparing for entry-into-force of the AP. An overall engagement plan has been developed with components designed to train government AP implementing agencies, inform policy makers, conduct outreach to industry and universities, make AP reporting software available and useful, and plan a detailed approach for implementing the declaration and complementary accessmore » provisions of the AP. DOE recently began collaborating with Indonesia, which has already entered the AP into force, requiring a second method of engagement somewhat different from that taken with countries that have not entered the AP into force. The AP international implementation program, administered by the International Nuclear Safeguards and Engagement Program, is working more closely with DOE’s International Nonproliferation Export Control Program to ensure countries are aware of and prepared to implement the export/import provisions of the AP. As the AP implementation program matures and helps move countries closer to entry-into-force or improved AP implementation, it is identifying characteristics of a country’s “end-state” that indicate that DOE assistance is no longer required. The U.S. AP Implementation Act and Senate Resolution of Ratification require the Administration to report annually to Congress on measures taken to achieve the adoption of the AP in non-nuclear weapon states. DOE’s AP international implementation program is a significant part of these measures. This paper describes recent developments to increase the scope and effectiveness of the program.« less

International Safeguards and the Pacific Northwest National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olsen, Khris B.; Smith, Leon E.; Frazar, Sarah L.

Established in 1965, Pacific Northwest National Laboratory’s (PNNL) strong technical ties and shared heritage with the nearby U.S. Department of Energy Hanford Site were central to the early development of expertise in nuclear fuel cycle signatures, separations chemistry, plutonium chemistry, environmental monitoring, modeling and analysis of reactor systems, and nuclear material safeguards and security. From these Hanford origins, PNNL has grown into a multi-program science and engineering enterprise that utilizes this diversity to strengthen the international safeguards regime. Today, PNNL supports the International Atomic Energy Agency (IAEA) in its mission to provide assurances to the international community that nations domore » not use nuclear materials and equipment outside of peaceful uses. PNNL also serves in the IAEA’s Network of Analytical Laboratories (NWAL) by providing analysis of environmental samples gathered around the world. PNNL is involved in safeguards research and development activities in support of many U.S. Government programs such as the National Nuclear Security Administration’s (NNSA) Office of Research and Development, NNSA Office of Nonproliferation and Arms Control, and the U.S. Support Program to IAEA Safeguards. In addition to these programs, PNNL invests internal resources including safeguards-specific training opportunities for staff, and laboratory-directed research and development funding to further ideas that may grow into new capabilities. This paper and accompanying presentation highlight some of PNNL’s contributions in technology development, implementation concepts and approaches, policy, capacity building, and human capital development, in the field of international safeguards.« less

75 FR 11223 - Lifting of Nonproliferation Measures Against One Russian Entity

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-10

... Entity AGENCY: Department of State. ACTION: Notice. SUMMARY: A determination has been made, pursuant to... on one Russian entity. DATES: Effective Date: March 10, 2010. FOR FURTHER INFORMATION CONTACT: Pamela... Order on the following Russian entity, its sub-units and successors: 1. Glavkosmos. These restrictions...

75 FR 5836 - Lifting of Nonproliferation Measures Against One Russian Entity

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-04

... Entity AGENCY: Department of State. ACTION: Notice. SUMMARY: A determination has been made, pursuant to... on one Russian entity. DATES: Effective Date: February 4, 2010. FOR FURTHER INFORMATION CONTACT... Executive Order on the following Russian entity, its sub-units and successors: 1. Baltic State Technical...

The Nuclear Power and Nuclear Weapons Connection.

ERIC Educational Resources Information Center

Leventhal, Paul

1990-01-01

Explains problems enforcing the Nuclear Non-Proliferation Treaty (NPT) of 1968. Provides factual charts and details concerning the production of nuclear energy and arms, the processing and disposal of waste products, and outlines the nuclear fuel cycle. Discusses safeguards, the risk of nuclear terrorism, and ways to deal with these problems. (NL)

78 FR 40132 - Proposed Subsequent Arrangement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... the retransfer of nuclear material of United States origin will not be inimical to the common defense.... Harrington, Deputy Administrator, Defense Nuclear Nonproliferation. [FR Doc. 2013-15981 Filed 7-2-13; 8:45 am... Concerning Civil Uses of Nuclear Energy Between the Government of the United States of America and the...

Proceedings of GLOBAL 2013: International Nuclear Fuel Cycle Conference - Nuclear Energy at a Crossroads

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2013-07-01

The Global conference is a forum for the discussion of the scientific, technical, social and regulatory aspects of the nuclear fuel cycle. Relevant topics include global utilization of nuclear energy, current fuel cycle technologies, advanced reactors, advanced fuel cycles, nuclear nonproliferation and public acceptance.

Alternate Funding Sources for the International Atomic Energy Agency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toomey, Christopher; Wyse, Evan T.; Kurzrok, Andrew J.

Since 1957, the International Atomic Energy Agency (IAEA) has worked to ensure the safe and responsible promotion of nuclear technology throughout the world. The IAEA operates at the intersection of the Nuclear Nonproliferation Treaty’s (NPT) fourth and third articles, which guarantee Parties to the Treaty the right to peaceful uses of nuclear technology, provided those activities are placed under safeguards verified by the IAEA. However, while the IAEA has enjoyed substantial success and prestige in the international community, there is a concern that its resources are being stretched to a point where it may no longer be possible to executemore » its multifaceted mission in its entirety. As noted by the Director General (DG) in 2008, demographics suggest that every aspect of the IAEA’s operations will be in higher demand due to increasing reliance on non-carbon-based energy and the concomitant nonproliferation, safety, and security risks that growth entails. In addition to these nuclear energy concerns, the demand for technical developmental assistance in the fields of food security, resource conservation, and human health is also predicted to increase as the rest of the world develops. Even with a 100% value-for-money rating by the U.S. Office of Management and Budget (OMB) and being described as an “extraordinary bargain” by the United Nations Secretary-General’s High-level Panel on Threats, Challenges and Change, real budget growth at the Agency has been limited to zero-real growth for a better part of the last two decades. Although the 2012 regular budget (RB) received a small increase for most programs, the 2013 RB has been set at zero-real growth. As a result, the IAEA has had to defer infrastructure investments, which has hindered its ability to provide the public goods its Members seek, decreased global security and development opportunities, and functionally transformed the IAEA into a charity, dependent on extrabudgetary (EB) contributions to sustain its mission and capabilities. To resolve these resource constraints, we recommend the creation of an endowment, funded entirely through private contributions. Our initial estimates for the endowment are that a €2B principal. This level of capitalization could provide significant support to all aspects of the IAEA’s mission, including Capital Investment and Innovation; Technical Cooperation; as well as incentivizing the policy and technology entrepreneurship that will be necessary for the future health of the nonproliferation regime. Given this potential, our future efforts will focus on a more rigorous assessment of the financial requirements, while simultaneously creating the beginnings of a functional organization. These include: organizational structure, metrics for grant-making and performance evaluation, and outreach and fundraising strategies. At the end of this process, there should be sufficient information and engagement to begin to operationalize the endowment through external funding sources.« less

Biology Intensive Orientation for Students (BIOS): A Biology "Boot Camp"

ERIC Educational Resources Information Center

Wischusen, Sheri Maples; Wischusen, E. William

2007-01-01

The Biology Intensive Orientation for Students (BIOS) Program was designed to assess the impact of a 5-d intensive prefreshman program on success and retention of biological science majors at Louisiana State University. The 2005 pilot program combined content lectures and examinations for BIOL 1201, Introductory Biology for Science Majors, as well…

Research Programs Constituting U.S. Participation in the International Biological Program.

ERIC Educational Resources Information Center

National Academy of Sciences--National Research Council, Washington, DC. Div. of Biology and Agriculture.

The United States contribution to the International Biological Program, which aims to understand more clearly the interrelationships within ecosystems, is centered on multidisciplinary research programs investigating the biological basis of ecological productivity and human welfare. Integrated research programs have been established for the…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hecker, Siegfried S.

Actions of the Government of the Democratic People's Republic of Korea have precipitated two nuclear crises in the past 10 years. The 1994 crisis was resolved through the 'Agreed Framework.' North Korea agreed to 'freeze' and eventually dismantle its nuclear program (with U.S. help to store spent fuel safely and under IAEA inspection). In return, the United States agreed (with the KEDO international consortium) to build two light-water reactors and supply North Korea with heavy-fuel oil until the reactors come on line. In addition, both sides agreed to move towards full normalization of relations, work for peace and security onmore » a nuclear-free Korean Peninsula, and work on strengthening the international nonproliferation regime. The second nuclear crisis erupted when North Korean Government officials allegedly admitted to having a clandestine uranium enrichment program when confronted with this accusation by U.S. officials in October 2002. The United States (through KEDO) suspended heavy-fuel oil shipments and North Korea responded by expelling the IAEA inspectors, withdrawing from the Nuclear Nonproliferation Treaty, and restarting its nuclear program in January 2003. The North Korean Government has invited Professor John Lewis of Stanford University, a China and North Korea scholar, for Track I1 discussions of nuclear and other key issues since 1987. In August 2003, Professor Lewis visited North Korea just before the first six-party talks, which were designed by the United States to solve the current nuclear crisis. Professor Lewis was invited back for the January 2004 visit. He asked Jack Pritchard, former U.S. special envoy for DRPK negotiations, and me to accompany him. Two Asian affairs staff specialists from the U.S. Senate Foreign Relations Committee also joined us. I will report on the visit to the Yongbyon Nuclear Scientific Research Center on January 8,2004. We toured the 5 MWe reactor, the 50 MWe reactor construction site, the spent fuel pool storage building, and the radiochemical laboratory. We concluded that North Korea has restarted its 5 MWe reactor (which produces roughly 6 kg of plutonium annually), it removed the 8000 spent fuel rods that were previously stored under IAEA safeguards from the spent fuel pool, and that it most likely extracted the 25 to 30 kg of plutonium contained in these fuel rods. Although North Korean officials showed us what they claimed was their plutonium metal product from this reprocessing campaign, we were not able to conclude definitively that it was in fact plutonium metal and that it came from the most recent reprocessing campaign. Nevertheless, our North Korean hosts demonstrated that they had the capability, the facility and requisite capacity, and the technical expertise to produce plutonium metal. We were not shown any facilities or had the opportunity to talk to technical or military experts who were able to address the issue of whether or not North Korea had a 'deterrent' as claimed - that is, we were not able to conclude that North Korea can build a nuclear device and that it can integrate nuclear devices into suitable delivery systems. On the matter of uranium enrichment programs, Vice Minister Kim Gye Gwan categorically denied that North Korea has a uranium enrichment program - he said, 'we have no program, no equipment, and no technical expertise for uranium enrichment.' Upon return to the United States, I shared my observations and analysis with U.S. Government officials in Washington, DC, including congressional testimony to the Senate Foreign Relations Committee and briefings to two House of Representative Committees.« less

Secretary of Energy Steven Chu speaks to the 2009 IAEA General Conference delegation

ScienceCinema

Secretary Chu

2017-12-09

On Sept. 14, 2009, U.S. Secretary of Energy Steven Chu addressed the 2009 IAEA General Conference delegation. Chu is the first Cabinet official to discuss President Obama's nuclear security and nonproliferation agenda outside the United States since the President delivered his landmark speech in Prague in April 2009.

76 FR 81004 - Imposition of Nonproliferation Measures Against Foreign Persons, Including a Ban on U.S...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-27

... control lists (Missile Technology Control Regime, Australia Group, Chemical Weapons Convention, Nuclear... the development of weapons of mass destruction (WMD) or cruise or ballistic missile systems. The... contribution to WMD or cruise or ballistic missile systems, (b) other items with the potential of making such a...

3 CFR - Delegation of Certain Functions Under Section 204(c) of the United States-India Nuclear...

Code of Federal Regulations, 2011 CFR

2011-01-01

...) of the United States-India Nuclear Cooperation Approval and Nonproliferation Enhancement Act (Public... Delegation of Certain Functions Under Section 204(c) of the United States-India Nuclear Cooperation Approval... the President by section 204(c) of the United States-India Nuclear Cooperation Approval and...

76 FR 42159 - Lifting of Sanctions on Person Associated With the A.Q. Khan Nuclear Procurement Network

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-18

... DEPARTMENT OF STATE [Public Notice: 7525] Lifting of Sanctions on Person Associated With the A.Q. Khan Nuclear Procurement Network AGENCY: Bureau of International Security and Nonproliferation, Department of State. ACTION: Notice. SUMMARY: A determination has been made to lift the measures imposed on...

The nuclear dilemma and the just war tradition

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Brien, W.V.; Langan, J.

This book presents papers on the ethical aspects of nuclear weapons. Topics considered include the concept of a ''just'' war, national defense, political aspects, religion and politics, the failure of deterrence, conventional warfare, nuclear deterrence and democratic politics, the future of the nuclear debate, non-proliferation policy, arms control, national security, and government policies.

Nuclear Proliferation in the Middle East: In Pursuit of a Regional Logic

DTIC Science & Technology

the Cold War allowed the sole superpower, the United States, to better manage proliferation issues and strengthen existing or create new multilateral...mechanisms to control these threats. In the recent, less structured multipolar environment, great powers came together to manage proliferation with their efforts bolstered by the nonproliferation regime.

Correction to: Expression of matrix metalloproteinase 12 is highly specific for non-proliferating invasive trophoblasts in the first trimester and temporally regulated by oxygen-dependent mechanisms including HIF-1A.

PubMed

Hiden, Ursula; Eyth, Christian P; Majali-Martinez, Alejandro; Desoye, Gernot; Tam-Amersdorfer, Carmen; Huppertz, Berthold; Ghaffari Tabrizi-Wizsy, Nassim

2018-01-01

In the original publication, the contribution of Dr. Christian Eyth as equal first author was not indicated. This has been corrected confirming that U. Hidden and C. Eyth contributed equally to this work.

Taking the Lead: Russia, the United States, and Nuclear Nonproliferation after Bush

DTIC Science & Technology

2008-12-01

2002), especially chap. 5; Henry D. Sokolski, ed., Pakistan’s Nuclear Future: Worries beyond War ( Carl - isle: SSI, January 2008); Henry Sokolski and...Two sides of this issue are argued in Scott D. Sagan and Kenneth N. Waltz, The Spread of Nuclear Weapons: A Debate (New York: W. W. Norton, 995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leonard, J.F.; Scheinman, A.M.

The Clinton administration has taken office at a moment of unparalleled opportunity in its relations with countries of the developing world. The end of the Cold War rivalry presents arms control possibilities that until recently seemed no more than rheotorical goals or idle dreams. If the advanced industrialized countries will treat these countries as full partners in the effort, a stunning series of arms control and security achievements are possible in the coming years. In this partnership, India, with its sheer size, technological and industrial sophistication and intellectual and diplomatic leadership role from the earliest years of its independence, shouldmore » play a key part. For most of the past 40 years, US and Indian foreign policies have worked at cross-purposes far more often than not. But there are reasons to hope that this will change, particularly with regard to arms control and nuclear non-proliferation. Chances for success will improve dramatically if the United States treats non-proliferation as a first-order interest not submerged by competing foreign policy concerns, and simultaneously places relations with India on a more regularized and institutionalized basis.« less

Chaperone-mediated autophagy degrades mutant p53

PubMed Central

Vakifahmetoglu-Norberg, Helin; Kim, Minsu; Xia, Hong-guang; Iwanicki, Marcin P.; Ofengeim, Dimitry; Coloff, Jonathan L.; Pan, Lifeng; Ince, Tan A.; Kroemer, Guido; Brugge, Joan S.; Yuan, Junying

2013-01-01

Missense mutations in the gene TP53, which encodes p53, one of the most important tumor suppressors, are common in human cancers. Accumulated mutant p53 proteins are known to actively contribute to tumor development and metastasis. Thus, promoting the removal of mutant p53 proteins in cancer cells may have therapeutic significance. Here we investigated the mechanisms that govern the turnover of mutant p53 in nonproliferating tumor cells using a combination of pharmacological and genetic approaches. We show that suppression of macroautophagy by multiple means promotes the degradation of mutant p53 through chaperone-mediated autophagy in a lysosome-dependent fashion. In addition, depletion of mutant p53 expression due to macroautophagy inhibition sensitizes the death of dormant cancer cells under nonproliferating conditions. Taken together, our results delineate a novel strategy for killing tumor cells that depend on mutant p53 expression by the activation of chaperone-mediated autophagy and potential pharmacological means to reduce the levels of accumulated mutant p53 without the restriction of mutant p53 conformation in quiescent tumor cells. PMID:23913924

Assessment of Gamma-Ray Spectra Analysis Method Utilizing the Fireworks Algorithm for various Error Measures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alamaniotis, Miltiadis; Tsoukalas, Lefteri H.

2018-01-01

Significant role in enhancing nuclear nonproliferation plays the analysis of obtained data and the inference of the presence or not of special nuclear materials in them. Among various types of measurements, gamma-ray spectra is the widest used type of data utilized for analysis in nonproliferation. In this chapter, a method that employs the fireworks algorithm (FWA) for analyzing gamma-ray spectra aiming at detecting gamma signatures is presented. In particular FWA is utilized to fit a set of known signatures to a measured spectrum by optimizing an objective function, with non-zero coefficients expressing the detected signatures. FWA is tested on amore » set of experimentally obtained measurements and various objective functions -MSE, RMSE, Theil-2, MAE, MAPE, MAP- with results exhibiting its potential in providing high accuracy and high precision of detected signatures. Furthermore, FWA is benchmarked against genetic algorithms, and multiple linear regression with results exhibiting its superiority over the rest tested algorithms with respect to precision for MAE, MAPE and MAP measures.« less

Studies in support of an SNM cutoff agreement: The PUREX exercise

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stanbro, W.D.; Libby, R.; Segal, J.

1995-07-01

On September 23, 1993, President Clinton, in a speech before the United Nations General Assembly, called for an international agreement banning the production of plutonium and highly enriched uranium for nuclear explosive purposes. A major element of any verification regime for such an agreement would probably involve inspections of reprocessing plants in Nuclear Nonproliferation Treaty weapons states. Many of these are large facilities built in the 1950s with no thought that they would be subject to international inspection. To learn about some of the problems that might be involved in the inspection of such large, old facilities, the Department ofmore » Energy, Office of Arms Control and Nonproliferation, sponsored a mock inspection exercise at the PUREX plant on the Hanford Site. This exercise examined a series of alternatives for inspections of the PUREX as a model for this type of facility at other locations. A series of conclusions were developed that can be used to guide the development of verification regimes for a cutoff agreement at reprocessing facilities.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benton, J; Wall, D; Parker, E

This paper presents the latest information on one of the Accelerated Highly Enriched Uranium (HEU) Disposition initiatives that resulted from the May 2002 Summit meeting between Presidents George W. Bush and Vladimir V. Putin. These initiatives are meant to strengthen nuclear nonproliferation objectives by accelerating the disposition of nuclear weapons-useable materials. The HEU Transparency Implementation Program (TIP), within the National Nuclear Security Administration (NNSA) is working to implement one of the selected initiatives that would purchase excess Russian HEU (93% 235U) for use as fuel in U.S. research reactors over the next ten years. This will parallel efforts to convertmore » the reactors' fuel core from HEU to low enriched uranium (LEU) material, where feasible. The paper will examine important aspects associated with the U.S. research reactor HEU purchase. In particular: (1) the establishment of specifications for the Russian HEU, and (2) transportation safeguard considerations for moving the HEU from the Mayak Production Facility in Ozersk, Russia, to the Y-12 National Security Complex in Oak Ridge, TN.« less

Space Science at Los Alamos National Laboratory

NASA Astrophysics Data System (ADS)

Smith, Karl

2017-09-01

The Space Science and Applications group (ISR-1) in the Intelligence and Space Research (ISR) division at the Los Alamos National Laboratory lead a number of space science missions for civilian and defense-related programs. In support of these missions the group develops sensors capable of detecting nuclear emissions and measuring radiations in space including γ-ray, X-ray, charged-particle, and neutron detection. The group is involved in a number of stages of the lifetime of these sensors including mission concept and design, simulation and modeling, calibration, and data analysis. These missions support monitoring of the atmosphere and near-Earth space environment for nuclear detonations as well as monitoring of the local space environment including space-weather type events. Expertise in this area has been established over a long history of involvement with cutting-edge projects continuing back to the first space based monitoring mission Project Vela. The group's interests cut across a large range of topics including non-proliferation, space situational awareness, nuclear physics, material science, space physics, astrophysics, and planetary physics.

Contributions to nuclear safety and radiation technologies in Ukraine by the Science and Technology Center in Ukraine (STCU)

NASA Astrophysics Data System (ADS)

Taranenko, L.; Janouch, F.; Owsiacki, L.

2001-06-01

This paper presents Science and Technology Center in Ukraine (STCU) activities devoted to furthering nuclear and radiation safety, which is a prioritized STCU area. The STCU, an intergovernmental organization with the principle objective of non-proliferation, administers financial support from the USA, Canada, and the EU to Ukrainian projects in various scientific and technological areas; coordinates projects; and promotes the integration of Ukrainian scientists into the international scientific community, including involving western collaborators. The paper focuses on STCU's largest project to date "Program Supporting Y2K Readiness at Ukrainian NPPs" initiated in April 1999 and designed to address possible Y2K readiness problems at 14 Ukrainian nuclear reactors. Other presented projects demonstrate a wide diversity of supported directions in the fields of nuclear and radiation safety, including reactor material improvement ("Improved Zirconium-Based Elements for Nuclear Reactors"), information technologies for nuclear industries ("Ukrainian Nuclear Data Bank in Slavutich"), and radiation health science ("Diagnostics and Treatment of Radiation-Induced Injuries of Human Biopolymers").

Summary Report of Summer 2009 NGSI Human Capital Development Efforts at Lawrence Livermore National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dougan, A; Dreicer, M; Essner, J

2009-11-16

In 2009, Lawrence Livermore National Laboratory (LLNL) engaged in several activities to support NA-24's Next Generation Safeguards Initiative (NGSI). This report outlines LLNL's efforts to support Human Capital Development (HCD), one of five key components of NGSI managed by Dunbar Lockwood in the Office of International Regimes and Agreements (NA-243). There were five main LLNL summer safeguards HCD efforts sponsored by NGSI: (1) A joint Monterey Institute of International Studies/Center for Nonproliferation Studies-LLNL International Safeguards Policy and Information Analysis Course; (2) A Summer Safeguards Policy Internship Program at LLNL; (3) A Training in Environmental Sample Analysis for IAEA Safeguards Internship;more » (4) Safeguards Technology Internships; and (5) A joint LLNL-INL Summer Safeguards Lecture Series. In this report, we provide an overview of these five initiatives, an analysis of lessons learned, an update on the NGSI FY09 post-doc, and an update on students who participated in previous NGSI-sponsored LLNL safeguards HCD efforts.« less

[Progress in synthetic biology of "973 Funding Program" in China].

PubMed

Chen, Guoqiang; Wang, Ying

2015-06-01

This paper reviews progresses made in China from 2011 in areas of "Synthetic Biology" supported by State Basic Research 973 Program. Till the end of 2014, 9 "synthetic biology" projects have been initiated with emphasis on "microbial manufactures" with the 973 Funding Program. Combined with the very recent launch of one project on "mammalian cell synthetic biology" and another on "plant synthetic biology", Chinese "synthetic biology" research reflects its focus on "manufactures" while not giving up efforts on "synthetic biology" of complex systems.

Development of a Biological Control Program for Eurasian Watermilfoil (Myriophyllum spicatum)

DTIC Science & Technology

2008-08-01

spicatum). Rawalpindi: Pakistan Station Commonwealth Institute of Biological Control. Gleason, H. A ., and A . Cronquist . 1991. Manual of vascular plants...ER D C/ EL T R- 08 -2 2 Aquatic Plant Control Research Program Development of a Biological Control Program for Eurasian Watermilfoil... a Biological Control Program for Eurasian Watermilfoil (Myriophyllum spicatum) Matthew J. W. Cock, Hariet L. Hinz, Gitta Grosskopf, and Patrick

Human Genome: DOE Origins

Science.gov Websites

Health and Environmental Research [OHER], the program that supported most Biology in the Department. The origins of DOE's biology program traced to the Manhattan Project, the World War II program that produced Technical Report; 1964 Impact of Radiation Biology on Fundamental Insights in Biology; DOE Technical Report

ICF quarterly report January - March 1997 volume 7, number 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murray, J

The National Ignition Facility Project The mission of the National Ignition Facility (NIF) is to produce ignition and modest energy gain in inertial confinement fusion (ICF) targets. Achieving these goals will maintain U.S. world leadership in ICF and will directly benefit the U.S. Department of Energy (DOE) missions in national security, science and technology, energy resources, and industrial competitiveness. Development and operation of the NIF are consistent with DOE goals for environmental quality, openness to the community, and nuclear nonproliferation and arms control. Although the primary mission of inertial fusion is for defense applications, inertial fusion research will provide criticalmore » information for the development of inertial fusion energy. The NIF, under construction at Lawrence Livermore National Laboratory (LLNL), is a cornerstone of the DOE's science-based Stockpile Stewardship Program for addressing high-energy-density physics issues in the absence of nuclear weapons testing. In pursuit of this mission, the DOE's Defense Programs has developed a state-of-the-art capability with the NIF to investigate high-energy-density physics in the laboratory with a microfusion capability for defense and energy applications. As a Strategic System Acquisition, the NIF Project has a separate and disciplined reporting chain to DOE as shown below.« less

International Internships in Nuclear Safeguards and Security: Challenges and Successes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duncan, Cristen L.; Heinberg, Cynthia L.; Killinger, Mark H.

2010-04-20

All students in the Russian safeguards and security degree programs at the National Research Nuclear University MEPhI and Tomsk Polytechnic University, sponsored by the Material Protection, Control and Accounting (MPC&A) Education Project, take part in a domestic internship at a Russian enterprise or facility. In addition, a select few students are placed in an international internship. These internships provide students with a better view of how MPC&A and nonproliferation in general are addressed outside of Russia. The possibility of an international internship is a significant incentive for students to enroll in the safeguards and security degree programs. The U.S. membersmore » of the MPC&A Education Project team interview students who have been nominated by their professors. These students must have initiative and reasonable English skills. The project team and professors then select students to be tentatively placed in various international internships during the summer or fall of their final year of study. Final arrangements are then made with the host organizations. This paper describes the benefits of the joint United States/Russia cooperation for next-generation workforce development, some of the international internships that have been carried out, the benefits of these international internships, and lessons learned in implementing them.« less

A comprehensive ban on nuclear testing.

PubMed

Neild, R; Ruina, J P

1972-01-14

Our foregoing analysis of the role of a comprehensive test ban leads us to the following conclusions. 1) A CTB by itself will have little direct effect on the arms race between the superpowers. It would not hinder their nuclear arms production and deployment nor would it necessarily present a significant obstacle to the development of new nuclear weapons systems, despite limiting the development of new nuclear warhead designs. It can hardly make a dent in the destructive capability of the superpowers or in their ability to step up the pace of the arms race. 2) The chief merits of a CTB reside in the political sphere. It would help promote detente and could help to escalate interest in arms control agreements of broader scope. But in neither of these effects would it be as significant as a successful SALT (strategic arms limitation talks) agreement. The CTB also lingers as a piece of unfinished business since the signing of the LTB in 1963. The question can be and has been raised, "If the superpowers are serious about arms control, why have they not accepted the CTB, which is simple in concept and in form and is also free of serious military risks?" Such doubts about the sincerity of the superpowers' willingness to limit their own arms development will persist as long as there is no CTB. Substantial agreement at SALT would lessen some of this effect too, but would not eliminate it completely. 3) Recent progress in seismic identification has been impressive, and other means of obtaining technical intelligence about nuclear testing have probably also improved greatly. In addition, research on the technical means of on-site inspection has demonstrated its limited effectiveness. Therefore, the role of on-site inspections as an added deterrent to cheating on a CTB has diminished substantially. This is not to say that detection and identification of all nuclear tests is possible now, or ever, but only that on-site inspection would add very little to the other technical means now available for verification. 4) It will become increasingly difficult in the United States to oppose the CTB on the basis of risks that accompany possible Soviet evasion of a treaty that does not include the right of onsite inspection. The opposition to a CTB is now likely to shift to the more direct argument that nuclear testing is important to keep pace with continuing worldwide technical and military developments. The justification for U.S. testing is only in part because of advances in Soviet nuclear technology per se. Those opposing a CTB may argue that it makes little sense, and may even be courting danger, to freeze nuclear technology alone and that banning nuclear tests should await an agreement that copes with all military research and development and all qualitative improvements in weapons systems. This directly confronts the argument that the unique virtue of a CTB is that it provides a simple and feasible first step in the very complicated problems of controlling military technology. 5) The mutual deterrence of the superpowers will not be compromised if a CTB agreement is reached and one side or the other clandestinely violates such an agreement. The state of nuclear technology in both countries is mature, and the destructive capability of their nuclear arsenals can be easily maintained. Whatever small improvements can come as a consequence of clandestine testing would hardly affect the strategic balance. 6) It seems unlikely that China and France will agree to stop testing in the near future. These countries refused to join the nonproliferation treaty, which did not affect their nuclear programs, and it is doubtful that, proceeding from military considerations alone, they would join a CTB. Their nuclear programs are still not mature, and a CTB would freeze their positions of inferiority with respect to the superpowers. There may, however, be wider political and security arrangements to induce them to participate. Cessation of tests by the other nuclear powers might serve as an inducement to China and France to refrain from testing. 7) The key near-nuclear powers, such as Japan, India, and Israel, are much more concerned with the military activities of their neighbors than they are with those of the superpowers. The modest nuclear restraints that a CTB imposes on the superpowers are hardly likely to have a direct impact on the approach of these countries to their own security. However, for these critical near-nuclear countries a CTB may be much more acceptable than the nonproliferation treaty. A CTB would not prohibit the production of fissionable material, the development of nuclear weapons technology short of testing, nor the stockpiling of untested nuclear weapons, and is therefore less restrictive. Consequently, these powers may be willing to ratify a CTB, but not the nonproliferation treaty. On the other hand, the CTB may provide them with a ready excuse for not succumbing to the pressure to ratify the nonproliferation treaty, if indeed they need excuses or would bow to such pressure. 8) A CTB is of very little added, direct significance to other nonnuclear powers who have already ratified or are about to ratify the nonproliferation treaty. It may only lessen their pique about the treaty's being highly discriminatory-the treaty imposes no restraints on the nuclear weapons programs of the nuclear powers, while the CTB restricts all parties to the agreement. 9) Peaceful nuclear explosions do not now show great promise and significance for economic development. What can be done with peaceful explosions can often be done by other means, although possibly at a slightly higher cost. On the other hand, making allowance for peaceful explosions greatly complicates a CTB. A useful approach to the problem of banning military tests but not foregoing indefinitely the use of peaceful explosions might, therefore, be to ban all nuclear explosions for a period of several years and to stipulate in the agreement that in that time there would be negotiations on how peaceful explosions may be controlled in a way that would not jeopardize the CTB.

The future of the NPT and measures to reduce nuclear dangers in the age of Trump

NASA Astrophysics Data System (ADS)

Kimball, Daryl G.

2017-11-01

Through the decades, the international nuclear disarmament and nonproliferation enterprise, though imperfect, has curbed nuclear proliferation and limited the number of nuclear-armed states to nine, forced reductions in major-power nuclear arsenals, ended nuclear testing by all but one state, and created an informal taboo against nuclear weapons use.

10 CFR 75.43 - Circumstances requiring advance notification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... referred to in Article III(2) of the Treaty on the Non-Proliferation of Nuclear Weapons, 21 U.S.T. 483). If... specified in this section. (b) Exports. Notification shall be given of any proposed shipment of nuclear material for peaceful purposes under an export license issued pursuant to part 110 of this chapter, in an...

10 CFR 75.43 - Circumstances requiring advance notification.

Code of Federal Regulations, 2014 CFR

2014-01-01

... referred to in Article III(2) of the Treaty on the Non-Proliferation of Nuclear Weapons, 21 U.S.T. 483). If... specified in this section. (b) Exports. Notification shall be given of any proposed shipment of nuclear material for peaceful purposes under an export license issued pursuant to part 110 of this chapter, in an...

10 CFR 75.43 - Circumstances requiring advance notification.

Code of Federal Regulations, 2012 CFR

2012-01-01

... referred to in Article III(2) of the Treaty on the Non-Proliferation of Nuclear Weapons, 21 U.S.T. 483). If... specified in this section. (b) Exports. Notification shall be given of any proposed shipment of nuclear material for peaceful purposes under an export license issued pursuant to part 110 of this chapter, in an...

10 CFR 75.43 - Circumstances requiring advance notification.

Code of Federal Regulations, 2013 CFR

2013-01-01

... referred to in Article III(2) of the Treaty on the Non-Proliferation of Nuclear Weapons, 21 U.S.T. 483). If... specified in this section. (b) Exports. Notification shall be given of any proposed shipment of nuclear material for peaceful purposes under an export license issued pursuant to part 110 of this chapter, in an...

10 CFR 75.43 - Circumstances requiring advance notification.

Code of Federal Regulations, 2011 CFR

2011-01-01

... referred to in Article III(2) of the Treaty on the Non-Proliferation of Nuclear Weapons, 21 U.S.T. 483). If... specified in this section. (b) Exports. Notification shall be given of any proposed shipment of nuclear material for peaceful purposes under an export license issued pursuant to part 110 of this chapter, in an...

Siegfried S. Hecker, Plutonium, and Nonproliferation

Science.gov Websites

controversy involving the stability of certain structures (or phases) in plutonium alloys near equilibrium Cold War is Over. What Now?, DOE Technical Report, April, 1995 6th US-Russian Pu Science Workshop * Aging of Plutonium and Its Alloys * A Tale of Two Diagrams * Plutonium and Its Alloys-From Atoms to

The EU and U.S. Strategies against Terrorism and Proliferation of WMD: A Comparative Study

DTIC Science & Technology

2007-01-01

attitude, which they see as simplistic. As French Foreign Minister Hubert Vedrine said in 2002, “For George W. Bush all the world’s problems come...EU’s Emerging Role in Nuclear Non-proliferation. Ed. by Marco Overhaus, Hanns W. Maull and Sebastian Harnisch, Volume 6, Newsletter No. 17, October

The Science of Nuclear Materials: A Modular, Laboratory-based Curriculum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cahill, C.L., E-mail: cahill@gwu.edu; Feldman, G.; Briscoe, W.J.

The development of a curriculum for nuclear materials courses targeting students pursuing Master of Arts degrees at The George Washington University is described. The courses include basic concepts such as radiation and radioactivity as well as more complex topics such the nuclear fuel cycle, nuclear weapons, radiation detection and technological aspects of non-proliferation.

76 FR 4228 - U.S.-India Bilateral Understanding: Revisions to U.S. Export and Reexport Controls Under the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-25

... nonproliferation objectives and their desire to expand high technology cooperation and trade, the two leaders... cooperation in civil space, defense and other high- technology sectors. These steps include removal of Indian... Technology Control Regime, Australia Group, and Wassenaar Arrangement) in a phased manner, and to consult...

An interdepartmental Ph.D. program in computational biology and bioinformatics: the Yale perspective.

PubMed

Gerstein, Mark; Greenbaum, Dov; Cheung, Kei; Miller, Perry L

2007-02-01

Computational biology and bioinformatics (CBB), the terms often used interchangeably, represent a rapidly evolving biological discipline. With the clear potential for discovery and innovation, and the need to deal with the deluge of biological data, many academic institutions are committing significant resources to develop CBB research and training programs. Yale formally established an interdepartmental Ph.D. program in CBB in May 2003. This paper describes Yale's program, discussing the scope of the field, the program's goals and curriculum, as well as a number of issues that arose in implementing the program. (Further updated information is available from the program's website, www.cbb.yale.edu.)

Radiation Detection Center on the Front Lines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hazi, A

2005-09-20

Many of today's radiation detection tools were developed in the 1960s. For years, the Laboratory's expertise in radiation detection resided mostly within its nuclear test program. When nuclear testing was halted in the 1990s, many of Livermore's radiation detection experts were dispersed to other parts of the Laboratory, including the directorates of Chemistry and Materials Science (CMS); Physics and Advanced Technologies (PAT); Defense and Nuclear Technologies (DNT); and Nonproliferation, Arms Control, and International Security (NAI). The RDC was formed to maximize the benefit of radiation detection technologies being developed in 15 to 20 research and development (R&D) programs. These effortsmore » involve more than 200 Laboratory employees across eight directorates, in areas that range from electronics to computer simulations. The RDC's primary focus is the detection, identification, and analysis of nuclear materials and weapons. A newly formed outreach program within the RDC is responsible for conducting radiation detection workshops and seminars across the country and for coordinating university student internships. Simon Labov, director of the RDC, says, ''Virtually all of the Laboratory's programs use radiation detection devices in some way. For example, DNT uses radiation detection to create radiographs for their work in stockpile stewardship and in diagnosing explosives; CMS uses it to develop technology for advancing the detection, diagnosis, and treatment of cancer; and the Energy and Environment Directorate uses radiation detection in the Marshall Islands to monitor the aftermath of nuclear testing in the Pacific. In the future, the National Ignition Facility will use radiation detection to probe laser targets and study shock dynamics.''« less

The Effects of Linear and Modified Linear Programed Materials on the Achievement of Slow Learners in Tenth Grade BSCS Special Materials Biology.

ERIC Educational Resources Information Center

Moody, John Charles

Assessed were the effects of linear and modified linear programed materials on the achievement of slow learners in tenth grade Biological Sciences Curriculum Study (BSCS) Special Materials biology. Two hundred and six students were randomly placed into four programed materials formats: linear programed materials, modified linear program with…

The inception and evolution of a unique masters program in cancer biology, prevention and control.

PubMed

Cousin, Carolyn; Blancato, Jan

2010-09-01

The University of the District of Columbia (UDC) and the Lombardi Comprehensive Cancer Center (LCCC), Georgetown University Medical Center established a Masters Degree Program in Cancer Biology, Prevention and Control at UDC that is jointly administered and taught by UDC and LCCC faculty. The goal of the Masters Degree Program is to educate students as master-level cancer professionals capable of conducting research and service in cancer biology, prevention, and control or to further advance the education of students to pursue doctoral studies. The Program's unique nature is reflected in its philosophy "the best cancer prevention and control researchers are those with a sound understanding of cancer biology". This program is a full-time, 2-year, 36-credit degree in which students take half of their coursework at UDC and half of their coursework at LCCC. During the second year, students are required to conduct research either at LCCC or UDC. Unlike most cancer biology programs, this unique Program emphasizes both cancer biology and cancer outreach training.

Model and Analytic Processes for Export License Assessments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thompson, Sandra E.; Whitney, Paul D.; Weimar, Mark R.

2011-09-29

This paper represents the Department of Energy Office of Nonproliferation Research and Development (NA-22) Simulations, Algorithms and Modeling (SAM) Program's first effort to identify and frame analytical methods and tools to aid export control professionals in effectively predicting proliferation intent; a complex, multi-step and multi-agency process. The report focuses on analytical modeling methodologies that alone, or combined, may improve the proliferation export control license approval process. It is a follow-up to an earlier paper describing information sources and environments related to international nuclear technology transfer. This report describes the decision criteria used to evaluate modeling techniques and tools to determinemore » which approaches will be investigated during the final 2 years of the project. The report also details the motivation for why new modeling techniques and tools are needed. The analytical modeling methodologies will enable analysts to evaluate the information environment for relevance to detecting proliferation intent, with specific focus on assessing risks associated with transferring dual-use technologies. Dual-use technologies can be used in both weapons and commercial enterprises. A decision-framework was developed to evaluate which of the different analytical modeling methodologies would be most appropriate conditional on the uniqueness of the approach, data availability, laboratory capabilities, relevance to NA-22 and Office of Arms Control and Nonproliferation (NA-24) research needs and the impact if successful. Modeling methodologies were divided into whether they could help micro-level assessments (e.g., help improve individual license assessments) or macro-level assessment. Macro-level assessment focuses on suppliers, technology, consumers, economies, and proliferation context. Macro-level assessment technologies scored higher in the area of uniqueness because less work has been done at the macro level. An approach to developing testable hypotheses for the macro-level assessment methodologies is provided. The outcome of this works suggests that we should develop a Bayes Net for micro-level analysis and continue to focus on Bayes Net, System Dynamics and Economic Input/Output models for assessing macro-level problems. Simultaneously, we need to develop metrics for assessing intent in export control, including the risks and consequences associated with all aspects of export control.« less

Joseph A. Burton Forum Award Lecture: Managing Nuclear and Biological Risks: Building Resilience through International Cooperation

NASA Astrophysics Data System (ADS)

Pregenzer, Arian

2012-03-01

International technical cooperation has long been an important nonproliferation strategy, especially since the 1990s when cooperative threat reduction (CTR) to prevent theft or illicit transfer of nuclear weapons, material and expertise in the former Soviet Union became a keystone of U.S. policy. The CTR approach expanded to include engagement with scientists and engineers with expertise relevant to biological and chemical weapons, and continued in the 2000s with efforts in Iraq and Libya, and cooperation with a wide range of countries on export control and nuclear and biological security. In general, the goal of such efforts has been to prevent proliferation or WMD terrorism. In most cases, the United States (or the West) defines the threat, and then funds partner countries to implement solutions. This presentation will argue that the future requires a new approach. Nuclear capabilities are more widely available than ever before, repercussions of the A.Q. Khan network continue to unfurl, and countries such as the DPRK engage in illicit cooperation. In addition, there has been a global boom in biotechnology with many nations, particularly across South and East Asia, investing in the biotech industry as a source of fuels, food, and materials for their rapidly expanding populations. Compared to the 1990s, today's threat is more diffuse, and the line between legitimate and illegitimate technical capability is no longer so clear. In addition, the West has many fewer resources to invest due to the global economic downturn. In this environment, full commitment of all countries that benefit from nuclear and biological advances will be required to assure the safety and security of all. Technical cooperation can continue to play an important role, but with some significant changes: First, challenges should be defined from a local perspective to ensure full commitment and participation. Second, the goal of cooperation should shift from preventing specific threats to building general capabilities to respond to a broad range of challenges as they arise. Finally, the funding model for technical cooperation should move from contractual arrangements to mutual investment and partnership, with regional approaches encouraged to add credibility, increase available resources, and help to ensure broad support.

Establishing a national biological laboratory safety and security monitoring program.

PubMed

Blaine, James W

2012-12-01

The growing concern over the potential use of biological agents as weapons and the continuing work of the Biological Weapons Convention has promoted an interest in establishing national biological laboratory biosafety and biosecurity monitoring programs. The challenges and issues that should be considered by governments, or organizations, embarking on the creation of a biological laboratory biosafety and biosecurity monitoring program are discussed in this article. The discussion focuses on the following questions: Is there critical infrastructure support available? What should be the program focus? Who should be monitored? Who should do the monitoring? How extensive should the monitoring be? What standards and requirements should be used? What are the consequences if a laboratory does not meet the requirements or is not willing to comply? Would the program achieve the results intended? What are the program costs? The success of a monitoring program can depend on how the government, or organization, responds to these questions.

Viral vectors for gene modification of plants as chem/bio sensors.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manginell, Monica; Harper, Jason C.; Arango, Dulce C.

2006-11-01

Chemical or biological sensors that are specific, sensitive, and robust allowing intelligence gathering for verification of nuclear non-proliferation treaty compliance and detouring production of weapons of mass destruction are sorely needed. Although much progress has been made in the area of biosensors, improvements in sensor lifetime, robustness, and device packaging are required before these devices become widely used. Current chemical and biological detection and identification techniques require less-than-covert sample collection followed by transport to a laboratory for analysis. In addition to being expensive and time consuming, results can often be inconclusive due to compromised sample integrity during collection and transport.more » We report here a demonstration of a plant based sensor technology which utilizes mature and seedling plants as chemical sensors. One can envision genetically modifying native plants at a site of interest that can report the presence of specific toxins or chemicals. In this one year project we used a developed inducible expression system to show the feasibility of plant sensors. The vector was designed as a safe, non-infectious vector which could be used to invade, replicate, and introduce foreign genes into mature host plants that then allow the plant to sense chem/bio agents. The genes introduced through the vector included a reporter gene that encodes for green fluorescent protein (GFP) and a gene that encodes for a mammalian receptor that recognizes a chemical agent. Specifically, GFP was induced by the presence of 17-{beta}-Estradiol (estrogen). Detection of fluorescence indicated the presence of the target chemical agent. Since the sensor is a plant, costly device packaging development or manufacturing of the sensor were not required. Additionally, the biological recognition and reporting elements are maintained in a living, natural environment and therefore do not suffer from lifetime disadvantages typical of most biosensing platforms. Detection of the chem/bio agent reporter (GFP) can be detected only at a specific wavelength.« less

Radiological Dispersal Devices: Select Issues in Consequence Management

DTIC Science & Technology

2004-12-07

STATEMENT Approved for public release, distribution unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17...Surveying the Security Risks, Center for Nonproliferation Studies, Monterey Institute of International Studies, January 2003; Anthony H. Cordesman...the radiation-exposure-related damage itself. For example, the DOD uses granisetron , an anti-vomiting drug, to allow soldiers to complete mission

The MANPAD Threat to Civilian Airliners

DTIC Science & Technology

2006-03-03

PAGES: 19 KEY TERMS: Homeland Security; Non-Proliferation; Airport Security CLASSIFICATION: Unclassified This paper investigates strategic approaches...technological solutions and law enforcement operations to provide a competent airport security perimeter.”18 To combat this ominous threat of MANPADS...sites for phone and computer tips should be established with access for airport security , local and federal law enforcement, as well as intelligence

Evaluating Nonproliferation Bona Fides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seward, Amy M.; Mathews, Caroline E.; Kessler, Carol E.

2008-07-14

Anticipated growth of global nuclear energy in a difficult international security environment heightens concerns that states could decide to exploit their civilian nuclear fuel cycles as a means of acquiring nuclear weapons. Such concerns partly reflect a fundamental tension in the Treaty on the Non-Proliferation of Nuclear Weapons (NPT). On the one hand, Articles II and III of the NPT clearly prohibit each non-nuclear-weapon state party from acquiring nuclear weapons. On the other hand, Article IV of the NPT confers the “inalienable right” of Parties to the treaty to “develop research, production and use of nuclear energy for peaceful purposes…,”more » and directs all Parties to “facilitate… the fullest possible exchange of equipment, materials and scientific and technological information for the peaceful uses of nuclear energy…,” and “cooperate in contributing…to the further development of the applications of nuclear energy for peaceful purposes….” This juxtaposition raises the possibility that a state could exercise its Article IV right to develop a civilian nuclear fuels cycle and then use the equipment, materials and technology to acquire nuclear weapons in violation of its Article II and III obligations.« less

A nonproliferating parvovirus vaccine vector elicits sustained, protective humoral immunity following a single intravenous or intranasal inoculation.

PubMed

Palmer, Gene A; Brogdon, Jennifer L; Constant, Stephanie L; Tattersall, Peter

2004-02-01

An ideal vaccine delivery system would elicit persistent protection following a single administration, preferably by a noninvasive route, and be safe even in the face of immunosuppression, either inherited or acquired, of the recipient. We have exploited the unique life cycle of the autonomous parvoviruses to develop a nonproliferating vaccine platform that appears to both induce priming and continually boost a protective immune response following a single inoculation. A crippled parvovirus vector was constructed, based on a chimera between minute virus of mice (MVM) and LuIII, which expresses Borrelia burgdorferi outer surface protein A (OspA) instead of its coat protein. The vector was packaged into an MVM lymphotropic capsid and inoculated into naive C3H/HeNcr mice. Vaccination with a single vector dose, either intravenously or intranasally, elicited high-titer anti-OspA-specific antibody that provided protection from live spirochete challenge and was sustained over the lifetime of the animal. Both humoral and cell-mediated Th(1) immunity was induced, as shown by anti-OspA immunoglobulin G2a antibody and preferential gamma interferon production by OspA-specific CD4(+) T cells.

A Nonproliferating Parvovirus Vaccine Vector Elicits Sustained, Protective Humoral Immunity following a Single Intravenous or Intranasal Inoculation

PubMed Central

Palmer, Gene A.; Brogdon, Jennifer L.; Constant, Stephanie L.; Tattersall, Peter

2004-01-01

An ideal vaccine delivery system would elicit persistent protection following a single administration, preferably by a noninvasive route, and be safe even in the face of immunosuppression, either inherited or acquired, of the recipient. We have exploited the unique life cycle of the autonomous parvoviruses to develop a nonproliferating vaccine platform that appears to both induce priming and continually boost a protective immune response following a single inoculation. A crippled parvovirus vector was constructed, based on a chimera between minute virus of mice (MVM) and LuIII, which expresses Borrelia burgdorferi outer surface protein A (OspA) instead of its coat protein. The vector was packaged into an MVM lymphotropic capsid and inoculated into naive C3H/HeNcr mice. Vaccination with a single vector dose, either intravenously or intranasally, elicited high-titer anti-OspA-specific antibody that provided protection from live spirochete challenge and was sustained over the lifetime of the animal. Both humoral and cell-mediated Th1 immunity was induced, as shown by anti-OspA immunoglobulin G2a antibody and preferential gamma interferon production by OspA-specific CD4+ T cells. PMID:14722265

The Space Shuttle Program and Its Support for Space Bioresearch

ERIC Educational Resources Information Center

Mason, J. A.; Heberlig, J. C.

1973-01-01

The Space Shuttle Program is aimed at not only providing low cost transportation to and from near earth orbit, but also to conduct important biological research. Fields of research identified include gravitational biology, biological rhythms, and radiation biology. (PS)

Biology. Focus on Excellence. Volume 1, Number 3.

ERIC Educational Resources Information Center

Penick, John E., Ed.; Bonnstetter, Ronald J.

The 1982 Search for Excellence in Science Education project has identified 10 exemplary programs in biology. Descriptions of the programs and the criteria used in their selection are presented. Chapter 1 discusses the desired state in biology education, examining the goals of biology education and how these goals relate to biology curriculum and…

Change is necessary in a biological engineering curriculum.

PubMed

Johnson, Arthur T; Montas, Hubert; Shirmohammadi, Adel; Wheaton, Fredrick W

2006-01-01

Success of a Biological Engineering undergraduate educational program can be measured in a number of ways, but however it is measured, a presently successful program can translate into an unsuccessful program if it cannot adjust to different conditions posed by technical advances, student characteristics, and academic pressures. Described in this paper is a Biological Engineering curriculum that has changed significantly since its transformation from Agricultural Engineering in 1993. As a result, student numbers have continued to climb, specific objectives have emerged, and unique courses have been developed. The Biological Resources Engineering program has evolved into a program that emphasizes breadth, fundamentals, communications skills, diversity, and practical engineering judgment.

Advanced Quantification of Plutonium Ionization Potential to Support Nuclear Forensic Evaluations by Resonance Ionization Mass Spectrometry

DTIC Science & Technology

2015-06-01

Research Committee nm Nanometer Np Neptunium NPT Treaty of Non-proliferation of Nuclear Weapons ns Nanosecond ps Picosecond Pu Plutonium RIMS...discovery—credited also to Fritz Strassman— scientists realized these reactions also emitted secondary neutrons . These secondary neutrons could in...destructive capabilities of nuclear fission and atomic weapons . Figure 1. Uranium-235 Fission chain reaction, from [1

Burma: Strategic Backwater or Strategic Fulcrum? U.S. Choices in the Bay of Bengal

DTIC Science & Technology

2013-05-01

with a Burmese prime minister and legislative membership under a colonial governor. Burman student groups were important in the wide number of...expressed broad policy objectives, which include non-proliferation, trafficking in persons, and global climate change and environmental issues...abuses of power by the tatmadaw, and environmental degradation stemming from rapid development. 4 These engagement activities are primarily focused

2015 Nuclear Fusion Prize acceptance speech

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldston, R. J.

This is the 2015 Nuclear Fusion Prize acceptance speech of R.J. Goldston: It is a great pleasure to receive the 2015 Nuclear Fusion award for my work developing a heuristic drift-based model for the power scrape-off width in tokamaks. I was particularly pleased to receive the award from IAEA Director General Yukiya Amano, whose thoughtful leadership has advanced the cause of nuclear non-proliferation mightily.

NUCLEAR NONPROLIFERATION AND SAFETY: Challenges Facing the International Atomic Energy Agency.

DTIC Science & Technology

1993-09-01

safeguards), and the Chernobyl nuclear power plant accident have focused greater attention on nuclear proliferation and the safety of nuclear power... Chernobyl , IAEA has placed increasing emphasis on assisting member states in improving the safety of nuclear power plants. Despite funding shortfalls...report language, GAO has incorporated their comments where appropriate. 2Nuclear Power Safety: Chernobyl Accident Prompted Worldwide Actions but

Commercial Nuclear Reprocessing in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sherrill, Charles Leland; Balatsky, Galya Ivanovna

2015-09-09

The short presentation outline: Reprocessing Overview; Events leading up to Carter’s Policy; Results of the decision; Policy since Nuclear Nonproliferation Act. Conclusions reached: Reprocessing ban has become an easy and visible fix to the public concern about proliferation, but has not completely stopped proliferation; and, Reprocessing needs to become detached from political considerations, so technical research can continue, regardless of the policy decisions we decide to take.

India-U.S. Relations

DTIC Science & Technology

2007-02-13

U.S. Relations Summary Long considered a “strategic backwater”from Washington’s perspective, South Asia has emerged in the 21st century as...South Asia focuses on ongoing tensions between India and Pakistan, a problem rooted in unfinished business from the 1947 Partition, competing claims to...weapons and ballistic missiles in South Asia . Both India and Pakistan have resisted external pressure to sign the major nonproliferation treaties

India-U.S. Relations

DTIC Science & Technology

2007-01-03

Summary Long considered a “strategic backwater”from Washington’s perspective, South Asia has emerged in the 21st century as increasingly vital to... Asia focuses on ongoing tensions between India and Pakistan, a problem rooted in unfinished business from the 1947 Partition, competing claims to the...and ballistic missiles in South Asia . Both India and Pakistan have resisted external pressure to sign the major nonproliferation treaties. In 1998

Indian-U.S. Relations

DTIC Science & Technology

2007-01-03

U.S. Relations Summary Long considered a “strategic backwater”from Washington’s perspective, South Asia has emerged in the 21st century as increasingly...in South Asia focuses on ongoing tensions between India and Pakistan, a problem rooted in unfinished business from the 1947 Partition, competing...nuclear weapons and ballistic missiles in South Asia . Both India and Pakistan have resisted external pressure to sign the major nonproliferation

Source Physics Experiment: Research in Support of Verification and Nonproliferation

DTIC Science & Technology

2011-09-01

designed to provide a carefully controlled seismic and strong motion data set from buried explosions at the Nevada National Security Site (NNSS). The...deposition partitioned into internal (heat and plastic strain) and kinetic (e.g., radiated seismic ) energy, giving more confidence in predicted free...ample information to study dry and water-saturated fractures, local lithology and topography on the radiated seismic wavefield. Spallation on

U.S. Nuclear Cooperation with India: Issues for Congress

DTIC Science & Technology

2008-11-03

separation list: ! 8 indigenous Indian power reactors ! Fast Breeder test Reactor (FTBR) and Prototype Fast Breeder Reactors (PFBR) under construction...facilities like reprocessing and enrichment plants and breeder reactors could be viewed as providing a significant nonproliferation benefit because the... breeder reactors would support the 2002 U.S. National Strategy to Combat Weapons of Mass Destruction, in which the United States pledged to “continue to

U.S. Nuclear Cooperation with India: Issues for Congress

DTIC Science & Technology

2008-10-02

8 indigenous Indian power reactors ! Fast Breeder test Reactor (FTBR) and Prototype Fast Breeder Reactors (PFBR) under construction ! Enrichment... breeder reactors could be viewed as providing a significant nonproliferation benefit because the materials produced by these plants are a few steps closer...to potential use in a bomb. In addition, safeguards on enrichment, reprocessing plants, and breeder reactors would support the 2002 U.S. National

Development of a Lithospheric Model and Geophysical Data Base for North Africa.

DTIC Science & Technology

1996-07-19

Department of Energy Office of Non-Proliferation and National Security MONITORED BY Phillips Laboratory CONTRACT No. F 19628-C-0104 The views and...Worldwide Standardized Seismograph Netowrk stations locatdd:.&t regional distances from magnitude greater than 5.•0 earthquakes occurring within N6rth... SECURITY CLASSIFICATION 18. SECURITY CLASSIFICATION 19. SECURITY CLASSIFICATION 20. LIMITATION OF ABSTRACTOF REPORT OF THIS PAGE OF ABSTRACT

Translations on Eastern Europe Political, Sociological, and Military Affairs No. 1361

DTIC Science & Technology

1977-03-07

focusing on theories and methods of late bourgeois, logical positivistic trends of a structuralistic mold reducing the complex and muUi...and articles on military and civil defense, organization, theory , budgets, and hardware. 17. Key Words and Document Analysis. 17a. Descriptors...unanimously emphasized its support for consolidation of administration for non-proliferation of nuclear arms. The political advisory committee, however

2015 Nuclear Fusion Prize acceptance speech

DOE PAGES

Goldston, R. J.

2016-12-19

This is the 2015 Nuclear Fusion Prize acceptance speech of R.J. Goldston: It is a great pleasure to receive the 2015 Nuclear Fusion award for my work developing a heuristic drift-based model for the power scrape-off width in tokamaks. I was particularly pleased to receive the award from IAEA Director General Yukiya Amano, whose thoughtful leadership has advanced the cause of nuclear non-proliferation mightily.

Promoting convergence: The integrated graduate program in physical and engineering biology at Yale University, a new model for graduate education.

PubMed

Noble, Dorottya B; Mochrie, Simon G J; O'Hern, Corey S; Pollard, Thomas D; Regan, Lynne

2016-11-12

In 2008, we established the Integrated Graduate Program in Physical and Engineering Biology (IGPPEB) at Yale University. Our goal was to create a comprehensive graduate program to train a new generation of scientists who possess a sophisticated understanding of biology and who are capable of applying physical and quantitative methodologies to solve biological problems. Here we describe the framework of the training program, report on its effectiveness, and also share the insights we gained during its development and implementation. The program features co-teaching by faculty with complementary specializations, student peer learning, and novel hands-on courses that facilitate the seamless blending of interdisciplinary research and teaching. It also incorporates enrichment activities to improve communication skills, engage students in science outreach, and foster a cohesive program cohort, all of which promote the development of transferable skills applicable in a variety of careers. The curriculum of the graduate program is integrated with the curricular requirements of several Ph.D.-granting home programs in the physical, engineering, and biological sciences. Moreover, the wide-ranging recruiting activities of the IGPPEB serve to enhance the quality and diversity of students entering graduate school at Yale. We also discuss some of the challenges we encountered in establishing and optimizing the program, and describe the institution-level changes that were catalyzed by the introduction of the new graduate program. The goal of this article is to serve as both an inspiration and as a practical "how to" manual for those who seek to establish similar programs at their own institutions. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):537-549, 2016. © 2016 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology.

Assessment of Impact of Monoenergetic Photon Sources on Prioritized Nonproliferation Applications: Simulation Study Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geddes, Cameron; Ludewigt, Bernhard; Valentine, John

Near-monoenergetic photon sources (MPSs) have the potential to improve sensitivity at greatly reduced dose in existing applications and enable new capabilities in other applications. MPS advantages include the ability to select energy, energy spread, flux, and pulse structures to deliver only the photons needed for the application, while suppressing extraneous dose and background. Some MPSs also offer narrow divergence photon beams which can target dose and/or mitigate scattering contributions to image contrast degradation. Current broad-band, bremsstrahlung photon sources (e.g., linacs and betatrons) deliver unnecessary dose that in some cases also interferes with the signature to be detected and/or restricts operations,more » and must be collimated (reducing flux) to generate narrow divergence beams. While MPSs can in principle resolve these issues, they are technically challenging to produce. Candidate MPS technologies for nonproliferation applications are now being developed, each of which have different properties (e.g. broad divergence vs. narrow). Within each technology, source parameters trade off against one another (e.g. flux vs. energy spread), representing a large operation space. To guide development, requirements for each application of interest must be defined and simulations conducted to define MPS parameters that deliver benefit relative to current systems. The present project conducted a broad assessment of potential nonproliferation applications where MPSs may provide new capabilities or significant performance enhancement (reported separately), which led to prioritization of several applications for detailed analysis. The applications prioritized were: cargo screening and interdiction of Special Nuclear Materials (SNM), detection of hidden SNM, treaty/dismantlement verification, and spent fuel dry storage cask content verification. High resolution imaging for stockpile stewardship was considered as a sub-area of the treaty topic, as it is also of interest for future treaty use. This report presents higher-fidelity calculations and modeling results to quantitatively evaluate the prioritized applications, and to derive the key MPS properties that drive application benefit. Simulations focused on the conventional signatures of radiography, photofission, and NRF to enable comparison to present methods and evaluation of benefit.« less

Fission-suppressed fusion breeder on the thorium cycle and nonproliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moir, R. W.

2012-06-19

Fusion reactors could be designed to breed fissile material while suppressing fissioning thereby enhancing safety. The produced fuel could be used to startup and makeup fuel for fission reactors. Each fusion reaction can produce typically 0.6 fissile atoms and release about 1.6 times the 14 MeV neutron's energy in the blanket in the fission-suppressed design. This production rate is 2660 kg/1000 MW of fusion power for a year. The revenues would be doubled from such a plant by selling fuel at a price of 60/g and electricity at $0.05/kWh for Q=P{sub fusion}/P{sub input}=4. Fusion reactors could be designed to destroymore » fission wastes by transmutation and fissioning but this is not a natural use of fusion whereas it is a designed use of fission reactors. Fusion could supply makeup fuel to fission reactors that were dedicated to fissioning wastes with some of their neutrons. The design for safety and heat removal and other items is already accomplished with fission reactors. Whereas fusion reactors have geometry that compromises safety with a complex and thin wall separating the fusion zone from the blanket zone where wastes could be destroyed. Nonproliferation can be enhanced by mixing {sup 233}U with {sup 238}U. Also nonproliferation is enhanced in typical fission-suppressed designs by generating up to 0.05 {sup 232}U atoms for each {sup 233}U atom produced from thorium, about twice the IAEA standards of 'reduced protection' or 'self protection.' With 2.4%{sup 232}U, high explosive material is predicted to degrade owing to ionizing radiation after a little over 1/2 year and the heat rate is 77 W just after separation and climbs to over 600 W ten years later. The fissile material can be used to fuel most any fission reactor but is especially appropriate for molten salt reactors (MSR) also called liquid fluoride thorium reactors (LFTR) because of the molten fuel does not need hands on fabrication and handling.« less

Impact of a Short Pre-Freshman Program on Retention

ERIC Educational Resources Information Center

Wischusen, Sheri M.; Wischusen, E. William; Pomarico, Steven M.

2011-01-01

The Biology Intensive Orientation for Students (BIOS) Program at Louisiana State University was designed to increase the success of incoming freshman biology majors in the first course in their major. The program combined content lectures and examinations for BIOL 1201-Introductory Biology for Science Majors, the first course in their major, as…

Development of Diagnostics for the Livermore DPF Devices

NASA Astrophysics Data System (ADS)

Mitrani, James; Prasad, Rahul R.; Podpaly, Yuri A.; Cooper, Christopher M.; Chapman, Steven F.; Shaw, Brian H.; Povilus, Alexander P.; Schmidt, Andrea

2017-10-01

LLNL is commissioning several new diagnostics to understand and optimize ion and neutron production in their dense plasma focus (DPF) systems. Gas fills used in DPF devices at LLNL are Deuterium (D2) and He accelerated onto a Be target, for production of neutrons. Neutron yields are currently measured with Helium-3 tubes, and development of yttrium-based activation detectors is currently underway. Neutron time-of-flight (nTOF) signals from prompt neutrons will be measured with gadolinium-doped liquid scintillators. An ion energy analyzer will be used to diagnose energy distribution of D + and He +2 ions. Additionally, a fast frame ICCD camera has been applied to image the plasma sheath during the rundown and pinch phases. Sheath velocity will be measured with an array of discrete photodiodes with ns time responses. A discussion of our results will be presented. Prepared by LLNL under Contract DE-AC52-07NA27344, and supported by the Laboratory Directed Research and Development Program (15-ERD-034) at LLNL and the Office of Defense Nuclear Nonproliferation Research and Development within U.S. Department of Energy.

Establishment of an Undergraduate Research and Training Program in Radiochemistry at Florida Memorial University, a Historically Black College or University (HBCU)

NASA Astrophysics Data System (ADS)

Tamalis, Dimitri; Stiffin, Rose; Elliott, Michael; Huisso, Ayivi; Biegalski, Steven; Landsberger, Sheldon

2009-08-01

With the passing of the Energy Policy Act of 2005, the United States is experiencing for the first time in over two decades, what some refer to as the "Nuclear Renaissance". The US Nuclear Regulatory Commission (NRC) recognizes this surge in application submissions and is committed to reviewing these applications in a timely manner to support the country's growing energy demands. Notwithstanding these facts, it is understood that the nuclear industry requires appropriately trained and educated personnel to support the growing needs of the nuclear industry and the US NRC. Equally important is the need to educate the next generation of students in nuclear non-proliferation, nuclear forensics and various aspects of homeland security for the national laboratories and the Department of Defense. From mechanical engineers educated and experienced in materials, thermal/fluid dynamics, and component failure analysis, to physicists using advanced computing techniques to design the next generation of nuclear reactor fuel elements, the need for new engineers, scientists, and health physicist has never been greater.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swift, Alicia L.

There is no better time than now to close the loophole in Article IV of the Nuclear Non-proliferation Treaty (NPT) that excludes military uses of fissile material from nuclear safeguards. Several countries have declared their intention to pursue and develop naval reactor technology, including Argentina, Brazil, Iran, and Pakistan, while other countries such as China, India, Russia, and the United States are expanding their capabilities. With only a minority of countries using low enriched uranium (LEU) fuel in their naval reactors, it is possible that a state could produce highly enriched uranium (HEU) under the guise of a nuclear navymore » while actually stockpiling the material for a nuclear weapon program. This paper examines the likelihood that non-nuclear weapon states exploit the loophole to break out from the NPT and also the regional ramifications of deterrence and regional stability of expanding naval forces. Possible solutions to close the loophole are discussed, including expanding the scope of the Fissile Material Cut-off Treaty, employing LEU fuel instead of HEU fuel in naval reactors, amending the NPT, creating an export control regime for naval nuclear reactors, and forming individual naval reactor safeguards agreements.« less

Status of the US RERTR Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Travelli, A.

1995-02-01

The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1994 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1993 in collaboration with its many international partners. The RERTR Program has moved aggressively to support President Clinton`s nonproliferation policy and his goal {open_quotes}to minimize the use of highly-enriched uranium in civil nuclear programs{close_quotes}. An Environmental Assessment which addresses the urgent-relief acceptance of 409 spent fuel elements was completed, and the first shipment of spent fuel elements is scheduledmore » for this month. An Environmental Impact Statement addressing the acceptance of spent research reactor fuel containing enriched uranium of U.S. origin is scheduled for completion by the end of June 1995. The U.S. administration has decided to resume development of high-density LEU research reactor fuels. DOE funding and guidance are expected to begin soon. A preliminary plan for the resumption of fuel development has been prepared and is ready for implementation. The scope and main technical activities of a plan to develop and demonstrate within the next five years the technical means needed to convert Russian-supplied research reactors to LEU fuels was agreed upon by the RERTR Program and four Russian institutes lead by RDIPE. Both Secretary O`Leary and Minister Michailov have expressed strong support for this initiative. Joint studies have made significant progress, especially in assessing the technical and economic feasibility of using reduced enrichment fuels in the SAFARI-I reactor in South Africa and in the Advanced Neutron Source reactor under design at ORNL. Significant progress was achieved on several aspects of producing {sup 99}Mo from fission targets utilizing LEU instead of HEU to the achievement of the common goal.« less

Evolution of different dual-use concepts in international and national law and its implications on research ethics and governance.

PubMed

Rath, Johannes; Ischi, Monique; Perkins, Dana

2014-09-01

This paper provides an overview of the various dual-use concepts applied in national and international non-proliferation and anti-terrorism legislation, such as the Biological and Toxin Weapons Convention, the Chemical Weapons Convention and United Nations Security Council Resolution 1540, and national export control legislation and in relevant codes of conduct. While there is a vast literature covering dual-use concepts in particular with regard to life sciences, this is the first paper that incorporates into such discussion the United Nations Security Council Resolution 1540. In addition, recent developments such as the extension of dual-use export control legislation in the area of human rights protection are also identified and reviewed. The discussion of dual-use concepts is hereby undertaken in the context of human- and/or national-security-based approaches to security. This paper discusses four main concepts of dual use as applied today in international and national law: civilian versus military, peaceful versus non-peaceful, legitimate versus illegitimate and benevolent versus malevolent. In addition, the usage of the term to describe positive technology spin-offs between civilian and military applications is also briefly addressed. Attention is also given to the roles civil society and research ethics may play in the governance of dual-use sciences and technologies.

Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cells.

PubMed

Wakasugi, Mitsuo; Sasaki, Takuma; Matsumoto, Megumi; Nagaoka, Miyuki; Inoue, Keiko; Inobe, Manabu; Horibata, Katsuyoshi; Tanaka, Kiyoji; Matsunaga, Tsukasa

2014-10-10

Histone H2A variant H2AX is phosphorylated at Ser(139) in response to DNA double-strand break (DSB) and single-stranded DNA (ssDNA) formation. UV light dominantly induces pyrimidine photodimers, which are removed from the mammalian genome by nucleotide excision repair (NER). We previously reported that in quiescent G0 phase cells, UV induces ATR-mediated H2AX phosphorylation plausibly caused by persistent ssDNA gap intermediates during NER. In this study, we have found that DSB is also generated following UV irradiation in an NER-dependent manner and contributes to an earlier fraction of UV-induced H2AX phosphorylation. The NER-dependent DSB formation activates ATM kinase and triggers the accumulation of its downstream factors, MRE11, NBS1, and MDC1, at UV-damaged sites. Importantly, ATM-deficient cells exhibited enhanced UV sensitivity under quiescent conditions compared with asynchronously growing conditions. Finally, we show that the NER-dependent H2AX phosphorylation is also observed in murine peripheral T lymphocytes, typical nonproliferating quiescent cells in vivo. These results suggest that in vivo quiescent cells may suffer from NER-mediated secondary DNA damage including ssDNA and DSB. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

Reduced changes in protein compared to mRNA levels across non-proliferating tissues.

PubMed

Perl, Kobi; Ushakov, Kathy; Pozniak, Yair; Yizhar-Barnea, Ofer; Bhonker, Yoni; Shivatzki, Shaked; Geiger, Tamar; Avraham, Karen B; Shamir, Ron

2017-04-18

The quantitative relations between RNA and protein are fundamental to biology and are still not fully understood. Across taxa, it was demonstrated that the protein-to-mRNA ratio in steady state varies in a direction that lessens the change in protein levels as a result of changes in the transcript abundance. Evidence for this behavior in tissues is sparse. We tested this phenomenon in new data that we produced for the mouse auditory system, and in previously published tissue datasets. A joint analysis of the transcriptome and proteome was performed across four datasets: inner-ear mouse tissues, mouse organ tissues, lymphoblastoid primate samples and human cancer cell lines. We show that the protein levels are more conserved than the mRNA levels in all datasets, and that changes in transcription are associated with translational changes that exert opposite effects on the final protein level, in all tissues except cancer. Finally, we observe that some functions are enriched in the inner ear on the mRNA level but not in protein. We suggest that partial buffering between transcription and translation ensures that proteins can be made rapidly in response to a stimulus. Accounting for the buffering can improve the prediction of protein levels from mRNA levels.

Growth of adult spinal cord in knifefish: Development and parametrization of a distributed model.

PubMed

Ilieş, Iulian; Sipahi, Rifat; Zupanc, Günther K H

2018-01-21

The study of indeterminate-growing organisms such as teleost fish presents a unique opportunity for improving our understanding of central nervous tissue growth during adulthood. Integrating the existing experimental data associated with this process into a theoretical framework through mathematical or computational modeling provides further research avenues through sensitivity analysis and optimization. While this type of approach has been used extensively in investigations of tumor growth, wound healing, and bone regeneration, the development of nervous tissue has been rarely studied within a modeling framework. To address this gap, the present work introduces a distributed model of spinal cord growth in the knifefish Apteronotus leptorhynchus, an established teleostean model of adult growth in the central nervous system. The proposed model incorporates two mechanisms, cell proliferation by active stem/progenitor cells and cell drift due to population pressure, both of which are subject to global constraints. A coupled reaction-diffusion equation approach was adopted to represent the densities of actively-proliferating and non-proliferating cells along the longitudinal axis of the spinal cord. Computer simulations using this model yielded biologically-feasible growth trajectories. Subsequent comparisons with whole-organism growth curves allowed the estimation of previously-unknown parameters, such as relative growth rates. Copyright © 2017 Elsevier Ltd. All rights reserved.

An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis

PubMed Central

Lin, Ching-Jung; Smibert, Peter; Zhao, Xiaoyu; Hu, Jennifer F.; Ramroop, Johnny; Kellner, Stefanie M.; Benton, Matthew A.; Govind, Shubha; Dedon, Peter C.; Sternglanz, Rolf; Lai, Eric C.

2015-01-01

N6-threonylcarbamoyl-adenosine (t6A) is one of the few RNA modifications that is universally present in life. This modification occurs at high frequency at position 37 of most tRNAs that decode ANN codons, and stabilizes cognate anticodon–codon interactions. Nearly all genetic studies of the t6A pathway have focused on single-celled organisms. In this study, we report the isolation of an extensive allelic series in the Drosophila ortholog of the core t6A biosynthesis factor Kae1. kae1 hemizygous larvae exhibit decreases in t6A that correlate with allele strength; however, we still detect substantial t6A-modified tRNAs even during the extended larval phase of null alleles. Nevertheless, complementation of Drosophila Kae1 and other t6A factors in corresponding yeast null mutants demonstrates that these metazoan genes execute t6A synthesis. Turning to the biological consequences of t6A loss, we characterize prominent kae1 melanotic masses and show that they are associated with lymph gland overgrowth and ectopic generation of lamellocytes. On the other hand, kae1 mutants exhibit other phenotypes that reflect insufficient tissue growth. Interestingly, whole-tissue and clonal analyses show that strongly mitotic tissues such as imaginal discs are exquisitely sensitive to loss of kae1, whereas nonproliferating tissues are less affected. Indeed, despite overt requirements of t6A for growth of many tissues, certain strong kae1 alleles achieve and sustain enlarged body size during their extended larval phase. Our studies highlight tissue-specific requirements of the t6A pathway in a metazoan context and provide insights into the diverse biological roles of this fundamental RNA modification during animal development and disease. PMID:26516084

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair.

PubMed

Murgia, Claudio; Caporale, Marco; Ceesay, Ousman; Di Francesco, Gabriella; Ferri, Nicola; Varasano, Vincenzo; de las Heras, Marcelo; Palmarini, Massimo

2011-03-01

Jaagsiekte sheep retrovirus (JSRV) is a unique oncogenic virus with distinctive biological properties. JSRV is the only virus causing a naturally occurring lung cancer (ovine pulmonary adenocarcinoma, OPA) and possessing a major structural protein that functions as a dominant oncoprotein. Lung cancer is the major cause of death among cancer patients. OPA can be an extremely useful animal model in order to identify the cells originating lung adenocarcinoma and to study the early events of pulmonary carcinogenesis. In this study, we demonstrated that lung adenocarcinoma in sheep originates from infection and transformation of proliferating type 2 pneumocytes (termed here lung alveolar proliferating cells, LAPCs). We excluded that OPA originates from a bronchioalveolar stem cell, or from mature post-mitotic type 2 pneumocytes or from either proliferating or non-proliferating Clara cells. We show that young animals possess abundant LAPCs and are highly susceptible to JSRV infection and transformation. On the contrary, healthy adult sheep, which are normally resistant to experimental OPA induction, exhibit a relatively low number of LAPCs and are resistant to JSRV infection of the respiratory epithelium. Importantly, induction of lung injury increased dramatically the number of LAPCs in adult sheep and rendered these animals fully susceptible to JSRV infection and transformation. Furthermore, we show that JSRV preferentially infects actively dividing cell in vitro. Overall, our study provides unique insights into pulmonary biology and carcinogenesis and suggests that JSRV and its host have reached an evolutionary equilibrium in which productive infection (and transformation) can occur only in cells that are scarce for most of the lifespan of the sheep. Our data also indicate that, at least in this model, inflammation can predispose to retroviral infection and cancer.

Tumour resistance to cisplatin: a modelling approach

NASA Astrophysics Data System (ADS)

Marcu, L.; Bezak, E.; Olver, I.; van Doorn, T.

2005-01-01

Although chemotherapy has revolutionized the treatment of haematological tumours, in many common solid tumours the success has been limited. Some of the reasons for the limitations are: the timing of drug delivery, resistance to the drug, repopulation between cycles of chemotherapy and the lack of complete understanding of the pharmacokinetics and pharmacodynamics of a specific agent. Cisplatin is among the most effective cytotoxic agents used in head and neck cancer treatments. When modelling cisplatin as a single agent, the properties of cisplatin only have to be taken into account, reducing the number of assumptions that are considered in the generalized chemotherapy models. The aim of the present paper is to model the biological effect of cisplatin and to simulate the consequence of cisplatin resistance on tumour control. The 'treated' tumour is a squamous cell carcinoma of the head and neck, previously grown by computer-based Monte Carlo techniques. The model maintained the biological constitution of a tumour through the generation of stem cells, proliferating cells and non-proliferating cells. Cell kinetic parameters (mean cell cycle time, cell loss factor, thymidine labelling index) were also consistent with the literature. A sensitivity study on the contribution of various mechanisms leading to drug resistance is undertaken. To quantify the extent of drug resistance, the cisplatin resistance factor (CRF) is defined as the ratio between the number of surviving cells of the resistant population and the number of surviving cells of the sensitive population, determined after the same treatment time. It is shown that there is a supra-linear dependence of CRF on the percentage of cisplatin-DNA adducts formed, and a sigmoid-like dependence between CRF and the percentage of cells killed in resistant tumours. Drug resistance is shown to be a cumulative process which eventually can overcome tumour regression leading to treatment failure.

The impact of international economic sanctions on Iranian cancer healthcare.

PubMed

Shahabi, Shohreh; Fazlalizadeh, Hooman; Stedman, Jennifer; Chuang, Linus; Shariftabrizi, Ahmad; Ram, Regina

2015-10-01

In 2012, Iranian's economy collapsed under strain from sanctions instituted to stop Iran from violating the International Nuclear Non-Proliferation Treaty. Sanctions have indirectly led to serious healthcare concerns, specifically cancer treatment. This is the first report to evaluate Iranian cancer healthcare while under international economic sanctions. Data and information were identified by searches of MEDLINE, PubMed, and references from relevant articles using the search terms: "Iran", "health policy", "sanctions", "ethics", and "cancer". Articles published in the English language between 1966 and present were included, based on relevance to sanctions or the specific case of sanctions in Iran. The Program of Action for Cancer Therapy evaluated Iran's National Cancer Control Program (NCCP), reporting it has substantial deficits, including prevention, diagnosis/treatment, palliative care, monitoring, and technology, with a serious drug shortage for cancer care. Sanctions have exemptions for medicines and food, but lead to disruption of health services through complications in transportation, transferring currencies or lack of money. There is increasing evidence that sanctions harm vulnerable populations, while blocking globalization and not creating political or social change quickly. Improvement of Iran's NCCP is not feasible, and the health of cancer patients will continue to decline while the sanctions are in effect. The solution is complex, but a modern and innovative approach to diplomacy, which includes human rights, is necessary. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

New Brunswick Laboratory. Progress report, October 1995--September 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Fiscal year (FY) 1996 was a very good year for New Brunswick Laboratory (NBL), whose major sponsor is the Office of Safeguards and Security (NN-51) in the US Department of Energy (DOE), Office of Nonproliferation and National Security, Office of Security Affairs. Several projects pertinent to the NBL mission were completed, and NBL`s interactions with partners and customers were encouraging. Among the partners with which NBL interacted in this report period were the International Atomic Energy Agency (IAEA), NN-51. Environmental Program Group of the DOE Chicago Operations Office, International Safeguards Project Office, Waste Isolation Pilot Plant (WIPP), Ukraine Working Group,more » Fissile Materials Assurance Working Group, National Institute of Standards and Technology (NIST), Nuclear Regulatory Commission (NRC), Institute for Reference Materials and Measurements (IRMM) in Belgium, Brazilian/Argentine Agency for Accounting and Control of Nuclear Materials (ABACC), Lockheed Idaho Technologies Company, and other DOE facilities and laboratories. NBL staff publications, participation in safeguards assistance and other nuclear programs, development of new reference materials, involvement in the updating and refinement of DOE documents, service in enhancing the science education of others, and other related activities enhanced NBL`s status among DOE laboratories and facilities. Noteworthy are the facts that NBL`s small inventory of nuclear materials is accurately accounted for, and, as in past years, its materials and human resources were used in peaceful nuclear activities worldwide.« less

Design and validation of general biology learning program based on scientific inquiry skills

NASA Astrophysics Data System (ADS)

Cahyani, R.; Mardiana, D.; Noviantoro, N.

2018-03-01

Scientific inquiry is highly recommended to teach science. The reality in the schools and colleges is that many educators still have not implemented inquiry learning because of their lack of understanding. The study aims to1) analyze students’ difficulties in learning General Biology, 2) design General Biology learning program based on multimedia-assisted scientific inquiry learning, and 3) validate the proposed design. The method used was Research and Development. The subjects of the study were 27 pre-service students of general elementary school/Islamic elementary schools. The workflow of program design includes identifying learning difficulties of General Biology, designing course programs, and designing instruments and assessment rubrics. The program design is made for four lecture sessions. Validation of all learning tools were performed by expert judge. The results showed that: 1) there are some problems identified in General Biology lectures; 2) the designed products include learning programs, multimedia characteristics, worksheet characteristics, and, scientific attitudes; and 3) expert validation shows that all program designs are valid and can be used with minor revisions. The first section in your paper.

Implementation and Assessment of a Molecular Biology and Bioinformatics Undergraduate Degree Program

ERIC Educational Resources Information Center

Pham, Daphne Q. -D.; Higgs, David C.; Statham, Anne; Schleiter, Mary Kay

2008-01-01

The Department of Biological Sciences at the University of Wisconsin-Parkside has developed and implemented an innovative, multidisciplinary undergraduate curriculum in Molecular Biology and Bioinformatics (MBB). The objective of the MBB program is to give students a hands-on facility with molecular biology theories and laboratory techniques, an…

Symposium: The Role of Biological Sciences in the Optometric Curriculum.

ERIC Educational Resources Information Center

And Others; Rapp, Jerry

1980-01-01

Papers from a symposium probing some of the curricular elements of the program in biological sciences at a school or college of optometry are provided. The overall program sequence in the biological sciences, microbiology, pharmacology, and the curriculum in the biological sciences from a clinical perspective are discussed. (Author/MLW)

Global Biology Research Program: Program plan

NASA Technical Reports Server (NTRS)

1983-01-01

Biological processes which play a dominant role in these cycles which transform and transfer much of this material throughout the biosphere are examined. A greater understanding of planetary biological processes as revealed by the interaction of the biota and the environment. The rationale, scope, research strategy, and research priorities of the global biology is presented.

Promoting Convergence: The Integrated Graduate Program in Physical and Engineering Biology at Yale University, a New Model for Graduate Education

ERIC Educational Resources Information Center

Noble, Dorottya B.; Mochrie, Simon G. J.; O'Hern, Corey S.; Pollard, Thomas D.; Regan, Lynne

2016-01-01

In 2008, we established the Integrated Graduate Program in Physical and Engineering Biology (IGPPEB) at Yale University. Our goal was to create a comprehensive graduate program to train a new generation of scientists who possess a sophisticated understanding of biology and who are capable of applying physical and quantitative methodologies to…

Towards programming languages for genetic engineering of living cells

PubMed Central

Pedersen, Michael; Phillips, Andrew

2009-01-01

Synthetic biology aims at producing novel biological systems to carry out some desired and well-defined functions. An ultimate dream is to design these systems at a high level of abstraction using engineering-based tools and programming languages, press a button, and have the design translated to DNA sequences that can be synthesized and put to work in living cells. We introduce such a programming language, which allows logical interactions between potentially undetermined proteins and genes to be expressed in a modular manner. Programs can be translated by a compiler into sequences of standard biological parts, a process that relies on logic programming and prototype databases that contain known biological parts and protein interactions. Programs can also be translated to reactions, allowing simulations to be carried out. While current limitations on available data prevent full use of the language in practical applications, the language can be used to develop formal models of synthetic systems, which are otherwise often presented by informal notations. The language can also serve as a concrete proposal on which future language designs can be discussed, and can help to guide the emerging standard of biological parts which so far has focused on biological, rather than logical, properties of parts. PMID:19369220

Towards programming languages for genetic engineering of living cells.

PubMed

Pedersen, Michael; Phillips, Andrew

2009-08-06

Synthetic biology aims at producing novel biological systems to carry out some desired and well-defined functions. An ultimate dream is to design these systems at a high level of abstraction using engineering-based tools and programming languages, press a button, and have the design translated to DNA sequences that can be synthesized and put to work in living cells. We introduce such a programming language, which allows logical interactions between potentially undetermined proteins and genes to be expressed in a modular manner. Programs can be translated by a compiler into sequences of standard biological parts, a process that relies on logic programming and prototype databases that contain known biological parts and protein interactions. Programs can also be translated to reactions, allowing simulations to be carried out. While current limitations on available data prevent full use of the language in practical applications, the language can be used to develop formal models of synthetic systems, which are otherwise often presented by informal notations. The language can also serve as a concrete proposal on which future language designs can be discussed, and can help to guide the emerging standard of biological parts which so far has focused on biological, rather than logical, properties of parts.

Reviewing the Nuclear Nonproliferation Treaty

DTIC Science & Technology

2010-05-01

aim was to determine the critical masses of nuclear explosives by tapping two subcritical masses toward each other with a screw- driver, all the...record. Not only has the IAEA failed to find existing covert reactors and fuel-making plants, which are critical to bomb making, the agency still...sort as possible will be critical if the NPT is to re- main effective against further proliferation. Certainly, such a goal informs the present vol

Russian Nonproliferation Policy and the Korean Peninsula

DTIC Science & Technology

2006-12-01

petroleum and natural gas, and potential market , Washington would not allow Russia to use Iran in its attempt to increase Russia’s influence in the...ASEM).30 The second goal is to open markets for Russia’s competitive products such as energy resources, high- tech weapons, and nuclear technology...to the Korean weaponry market that the United States has monopolized, its entry into world economic organizations, and, finally, its security

U.S.-China Counterterrorism Cooperation: Issues for U.S. Policy

DTIC Science & Technology

2008-10-08

detained Uighurs at Guantanamo Bay prison; weapons nonproliferation; port security; security for the Olympics in Beijing in August 2008; sanctions...the others for Resolution 1368 (to combat terrorism). On September 20, Beijing said that it offered “unconditional support” in fighting terrorism...transform — the closer bilateral relationship pursued by President Bush since late 2001. In the short-term, U.S. security policy toward Beijing sought

Unattended Radiation Sensor Systems for Remote Terrestrial Applications and Nuclear Nonproliferation

DTIC Science & Technology

2002-01-01

liquid nitrogen is not available, or frequent attention is inconvenient and time-consuming. The “box” section contains a Stirling engine cryocooler and...sponsorship of the Defense Threat Reduction Agency (DTRA). The first is a system consisting of a mechanical cryocooler coupled with a high-purity...amplifier, a multichannel analyzer, and gated integrator electronics to process the slow signal pulses generated by room temperature solid state detectors

Arms Control and Nonproliferation: A Catalog of Treaties and Agreements

DTIC Science & Technology

2011-03-23

produced two agreements— the Interim Agreement ... on Certain Measures with Respect to the Limitation of...Iranian missile threat. The system was to include 10 interceptors based in Poland and a radar in the Czech Republic . Russia’s former President Putin and...that Moscow would not do so if the United States reversed its plan to emplace GMD facilities in Poland and the Czech Republic . Congress resisted the

Russian Political, Economic, and Security Issues and U.S. Interests

DTIC Science & Technology

2008-08-26

concerns and on nuclear non-proliferation in general. Russia’s actions in Georgia, however, could be a turning point in U.S.-Russian relations...Russia’s actions also arouse anxiety in other Soviet successor states, especially those with large Russian minorities, such as Ukraine and Kazakhstan...transforming Yukos into a major global energy company. Khodorkovski criticized some of Putin’s actions , financed anti-Putin political parties, and hinted

Russian Political, Economic, and Security Issues and U.S. Interests

DTIC Science & Technology

2008-10-06

concerns and on nuclear non-proliferation in general. Russia’s actions in Georgia, however, could be a turning point in U.S.-Russian relations. Russia’s... actions also arouse anxiety in other Soviet successor states, especially those with large Russian minorities, such as Ukraine and Kazakhstan...into a major global energy company. Khodorkovski criticized some of Putin’s actions , financed anti-Putin political parties, and hinted that he might

Libya: Background and U.S. Relations

DTIC Science & Technology

2007-06-19

entered a period of increasing international isolation. The compounded effects of a loss of oil revenue, restrictions on the travel of senior officials...his 27- CRS-8 10 Sunday Times (London), “Focus: Was Justice Done?” October 23, 2005; Magnus Linklater, “It’s Time To Look Again at Lockerbie,” The...operate more effectively and capitalize on new opportunities” in Libya. The Administration also requests $300,000 in Nonproliferation, Antiterrorism & De

Armed and Dangerous? UAVs and U.S. Security

DTIC Science & Technology

2014-01-01

MEMS] as inertial navigation units [INUs]. This technology is widely used in commercial products, such as toy helicopters and Wii controllers. The...aircraft? In conclusion, both the MTCR and Wassenaar Arrange- ment provide the United States with the flexibility and controls to be able to balance its...security and nonproliferation goals with respect to armed UAVs. Perhaps more problematic is whether the government interagency can strike a balance

Arms Control and Nonproliferation: A Catalog of Treaties and Agreements

DTIC Science & Technology

2007-08-09

security and control over nuclear weapons and fissile materials. These projects provided Russia with bullet-proof Kevlar blankets, secure canisters ...U.S. security concerns. The United States and Soviet Union began to sign agreements limiting their strategic offensive nuclear weapons in the early...U.S.-Russian relationship. At the same time, however, the two sides began to cooperate on securing and eliminating Soviet-era nuclear , chemical, and

International Partnerships to Combat Weapons of Mass Destruction

DTIC Science & Technology

2008-05-01

public, plant , and animal), medicine , economics, law enforcement, and the scientific process itself—and thus engage a range of expert and stakeholder...OCCASIONAL PAPER 6 and replace them with fossil fuel plants ; a multilateral effort to dispose of 34 tons of Russian plutonium; and a number of...nonproliferation benefits: there is no technology ‘silver bullet’ that can be built into an enrichment plant or reprocessing plant that can prevent a

Numerical Experiments Investigating the Source of Explosion S-Waves

DTIC Science & Technology

2007-09-01

simulations in this study are based on the well-recorded 1993 Nonproliferation experiment (NPE) ( chemical kiloton). A regional 3-dimensional model...1-kiloton chemical explosion at the NTS. NPE details and research reports can be found in Denny and Stull (1994). Figure 3 shows the extensive...T., D. Helmberger, and G. Engen (1985). Evidence for tectonic release from underground nuclear explosions in long period S waves, Bull. Seismol. Soc

U.S.-China Military Contacts: Issues for Congress

DTIC Science & Technology

2013-07-25

military spending and doctrine , missile and nuclear nonproliferation, and other important U.S. security interests. Then, in the National Defense...the islands. Since the PRC is not an archipelagic country, it is not allowed to draw straight archipelagic baselines. The U.S. Navy may conduct...Senior Colonel based in Washington spoke officially and in uniform at the U.S. Army Training and Doctrine Command (TRADOC) in Virginia. Finally, if

Air and Space Power Journal. Volume 29, Number 4. July-August 2015

DTIC Science & Technology

2015-08-01

Afghanistan, and Pakistan. It is incredibly difficult to prevent these attacks when the most explicit strategies are reactive ex post facto military...Editor, Strategic Studies Quarterly Air Force Research Institute Dr. Grant T. Hammond USAF Center for Strategy and Technology Dr. Dale L. Hayden Air Force...of War Studies at King’s College London, researches nonproliferation, terrorism, and US security policy. He observes that deterrence strategies

Keeping up With The Neighbors: Nonproliferation and Implementation of UNSCR 1540

DTIC Science & Technology

2016-02-15

of Acts of Nuclear Terrorism (ICSANT) 25 3.2. Voluntary Commitments 3.2.1. International Atomic Energy Agency ( IAEA ) membership 3.2.2... IAEA Nuclear Security Fund contributions 3.2.7. Bilateral or multilateral assistance 3.2.8. Centers of Excellence 3.3. International Assurances...CPPNM implementation authority 4.2.2. National legal framework for CPPNM 4.3. Safeguards Adherence and Compliance 4.3.1. IAEA safeguards agreement

U.S.-Russian cooperation in nuclear disarmament and nonproliferation

NASA Astrophysics Data System (ADS)

Podvig, Pavel

2010-02-01

The United States and Russia, the two largest nuclear powers, have a special obligation to provide leadership in nuclear disarmament and in strengthening the nuclear non-proliferation regime. In the past year the two countries made an effort to restart the arms control process by concluding a new treaty that would bring their legal disarmament obligations in line with the realities of their post-cold war relationships. The process of negotiating deeper nuclear reductions in the new environment turned out to be rather difficult, since the approaches that the countries used in the past are not well suited to dealing with issues like conversion of strategic nuclear delivery systems to conventional missions, tactical nuclear weapons, or dismantlement of nuclear warheads. This presentation considers the recent progress in U.S.-Russian arms control process and outlines the key issues at the negotiations. It also considers prospects for further progress in bilateral nuclear disarmament and issues that will be encountered at later stages of the process. The author argues that success of the arms reductions will depend on whether the United States and Russia will be able to build an institutional framework for cooperation on a range of issues - from traditional arms control to securing nuclear materials and from missile defense to strengthening the international nuclear safeguards. )

Oxidation and Assimilation of Carbohydrates by Micrococcus sodonensis1

PubMed Central

Perry, Jerome J.; Evans, James B.

1966-01-01

Perry, Jerome J. (North Carolina State University, Raleigh), and James B. Evans. Oxidation and assimilation of carbohydrates by Micrococcus sodonensis. J. Bacteriol. 91:33–38. 1966.—Micrococcus sodonensis is a biotin-requiring strict aerobe that cannot utilize carbohydrates as sole sources of carbon and energy. However, addition of mannose, glucose, sucrose, or maltose to a medium on which the organism can grow resulted in an increase in total growth. M. sodonensis oxidized these sugars without induction, thus indicating the presence of constitutive enzymes for their transport, activation, and metabolism. Under appropriate nonproliferating cell conditions, glucose was readily incorporated into essential constituents of the cell. When glucose-1-C14 and glucose-6-C14 were oxidized by nonproliferating cells, the label was found in both the protein and nucleic acid fractions of the cell. The respiratory quotients of cells oxidizing glucose in saline and in phosphate buffer indicated assimilation of sugar carbon in buffer and virtually no assimilation in saline. The ability of M. sodonensis to completely oxidize glucose and to grow on intermediates of glucose oxidation but not on glucose suggests that glucose may suppress or repress some reaction(s) necessary for growth, and that growth substrates either derepress or circumvent this block. PMID:5903100

The future role of next-generation DNA sequencing and metagenetics in aquatic biology monitoring programs

EPA Science Inventory

The development of current biological monitoring and bioassessment programs was a drastic improvement over previous programs created for monitoring a limited number of specific chemical pollutants. Although these assessment programs are better designed to address the transient an...

UC Merced Center for Computational Biology Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Colvin, Michael; Watanabe, Masakatsu

Final report for the UC Merced Center for Computational Biology. The Center for Computational Biology (CCB) was established to support multidisciplinary scientific research and academic programs in computational biology at the new University of California campus in Merced. In 2003, the growing gap between biology research and education was documented in a report from the National Academy of Sciences, Bio2010 Transforming Undergraduate Education for Future Research Biologists. We believed that a new type of biological sciences undergraduate and graduate programs that emphasized biological concepts and considered biology as an information science would have a dramatic impact in enabling the transformationmore » of biology. UC Merced as newest UC campus and the first new U.S. research university of the 21st century was ideally suited to adopt an alternate strategy - to create a new Biological Sciences majors and graduate group that incorporated the strong computational and mathematical vision articulated in the Bio2010 report. CCB aimed to leverage this strong commitment at UC Merced to develop a new educational program based on the principle of biology as a quantitative, model-driven science. Also we expected that the center would be enable the dissemination of computational biology course materials to other university and feeder institutions, and foster research projects that exemplify a mathematical and computations-based approach to the life sciences. As this report describes, the CCB has been successful in achieving these goals, and multidisciplinary computational biology is now an integral part of UC Merced undergraduate, graduate and research programs in the life sciences. The CCB began in fall 2004 with the aid of an award from U.S. Department of Energy (DOE), under its Genomes to Life program of support for the development of research and educational infrastructure in the modern biological sciences. This report to DOE describes the research and academic programs made possible by the CCB from its inception until August, 2010, at the end of the final extension. Although DOE support for the center ended in August 2010, the CCB will continue to exist and support its original objectives. The research and academic programs fostered by the CCB have led to additional extramural funding from other agencies, and we anticipate that CCB will continue to provide support for quantitative and computational biology program at UC Merced for many years to come. Since its inception in fall 2004, CCB research projects have continuously had a multi-institutional collaboration with Lawrence Livermore National Laboratory (LLNL), and the National Center for Supercomputing Applications at the University of Illinois at Urbana-Champaign, as well as individual collaborators at other sites. CCB affiliated faculty cover a broad range of computational and mathematical research including molecular modeling, cell biology, applied math, evolutional biology, bioinformatics, etc. The CCB sponsored the first distinguished speaker series at UC Merced, which had an important role is spreading the word about the computational biology emphasis at this new campus. One of CCB's original goals is to help train a new generation of biologists who bridge the gap between the computational and life sciences. To archive this goal, by summer 2006, a new program - summer undergraduate internship program, have been established under CCB to train the highly mathematical and computationally intensive Biological Science researchers. By the end of summer 2010, 44 undergraduate students had gone through this program. Out of those participants, 11 students have been admitted to graduate schools and 10 more students are interested in pursuing graduate studies in the sciences. The center is also continuing to facilitate the development and dissemination of undergraduate and graduate course materials based on the latest research in computational biology.« less

The NASA Space Biology Program

NASA Technical Reports Server (NTRS)

Halstead, T. W.

1982-01-01

A discussion is presented of the research conducted under the auspices of the NASA Space Biology Program. The objectives of this Program include the determination of how gravity affects and how it has shaped life on earth, the use of gravity as a tool to investigate relevant biological questions, and obtaining an understanding of how near-weightlessness affects both plants and animals in order to enhance the capability to use and explore space. Several areas of current developmental research are discussed and the future focus of the Program is considered.

An Experimental Study of a BSCS-Style Laboratory Approach for University General Biology.

ERIC Educational Resources Information Center

Leonard, William H.

1983-01-01

A Biological Sciences Curriculum Study (BSCS) inquiry approach for university general biology laboratory was tested against a well-established commercial program judged to be highly directive. The BSCS was found to be more effective in learning biology laboratory concepts than the commercial program as measured by a laboratory concepts test.…

Explorations: A Research-Based Program Introducing Undergraduates to Diverse Biology Research Topics Taught by Grad Students and Postdocs

ERIC Educational Resources Information Center

Brownell, Sara E.; Khalfan, Waheeda; Bergmann, Dominique; Simoni, Robert

2013-01-01

Undergraduate biology majors are often overwhelmed by and underinformed about the diversity and complexity of biological research that is conducted on research-intensive campuses. We present a program that introduces undergraduates to the diversity and scope of biological research and also provides unique teaching opportunities for graduate…

Promoting convergence: The integrated graduate program in physical and engineering biology at Yale University, a new model for graduate education

PubMed Central

Noble, Dorottya B.; Mochrie, Simon G. J.; O'Hern, Corey S.; Pollard, Thomas D.

2016-01-01

Abstract In 2008, we established the Integrated Graduate Program in Physical and Engineering Biology (IGPPEB) at Yale University. Our goal was to create a comprehensive graduate program to train a new generation of scientists who possess a sophisticated understanding of biology and who are capable of applying physical and quantitative methodologies to solve biological problems. Here we describe the framework of the training program, report on its effectiveness, and also share the insights we gained during its development and implementation. The program features co‐teaching by faculty with complementary specializations, student peer learning, and novel hands‐on courses that facilitate the seamless blending of interdisciplinary research and teaching. It also incorporates enrichment activities to improve communication skills, engage students in science outreach, and foster a cohesive program cohort, all of which promote the development of transferable skills applicable in a variety of careers. The curriculum of the graduate program is integrated with the curricular requirements of several Ph.D.‐granting home programs in the physical, engineering, and biological sciences. Moreover, the wide‐ranging recruiting activities of the IGPPEB serve to enhance the quality and diversity of students entering graduate school at Yale. We also discuss some of the challenges we encountered in establishing and optimizing the program, and describe the institution‐level changes that were catalyzed by the introduction of the new graduate program. The goal of this article is to serve as both an inspiration and as a practical “how to” manual for those who seek to establish similar programs at their own institutions. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):537–549, 2016. PMID:27292366

NABS Program: (Native Americans in Biological Science).

ERIC Educational Resources Information Center

Gettys, Nancy, Comp.

1994-01-01

Describes the four-week summer program of the Native Americans in Biological Sciences Program that engages Native American eighth- and ninth-grade students in studying the problems related to the waste water treatment plant in Cushing, Oklahoma. (MDH)

Preparing Future Biology Faculty: An Advanced Professional Development Program for Graduate Students

ERIC Educational Resources Information Center

Lockwood, Stephanie A.; Miller, Amanda J.; Cromie, Meghan M.

2014-01-01

Formal professional development programs for biology graduate students interested in becoming faculty members have come far; however, programs that provide advanced teaching experience for seasoned graduate teaching assistants are scarce. We outline an advanced program that focuses on further training of graduate teaching assistants in pedagogy…

NASA Space Biology Research Associate Program for the 21st Century

NASA Technical Reports Server (NTRS)

Sonnenfeld, Gerald

1999-01-01

The Space Biology Research Associate Program for the 21st Century provided a unique opportunity to train individuals to conduct biological research in hypo- and hyper-gravity, and to conduct ground-based research. This grant was developed to maximize the potential for Space Biology as an emerging discipline and to train a cadre of space biologists. The field of gravitational and space biology is rapidly growing at the future of the field is reflected in the quality and education of its personnel. Our chief objective was to train and develop these scientists rapidly and in a cost effective manner. The program began on June 1, 1980 with funding to support several Research Associates each year. 113 awards, plus 1 from an independently supported minority component were made for the Research Associates program. The program was changed from a one year award with a possibility for renewal to a two year award. In 1999, the decision was made by NASA to discontinue the program due to development of new priorities for funding. This grant was discontinued because of the move of the Program Director to a new institution; a new grant was provided to that new institution to allow completion of the training of the remaining 2 research associates in 1999. After 1999, the program will be discontinued.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stillman, J. A.; Feldman, E. E.; Wilson, E. H.

This report contains the results of reactor accident analyses for the University of Missouri Research Reactor (MURR). The calculations were performed as part of the conversion from the use of highly-enriched uranium (HEU) fuel to the use of low-enriched uranium (LEU) fuel. The analyses were performed by staff members of the Global Threat Reduction Initiative (GTRI) Reactor Conversion Program at the Argonne National Laboratory (ANL), the MURR Facility, and the Nuclear Engineering Program – College of Engineering, University of Missouri-Columbia. The core conversion to LEU is being performed with financial support from the U. S. government. This report contains themore » results of reactor accident analyses for the University of Missouri Research Reactor (MURR). The calculations were performed as part of the conversion from the use of highly-enriched uranium (HEU) fuel to the use of low-enriched uranium (LEU) fuel. The analyses were performed by staff members of the Global Threat Reduction Initiative (GTRI) Reactor Conversion Program at the Argonne National Laboratory (ANL), the MURR Facility, and the Nuclear Engineering Program – College of Engineering, University of Missouri-Columbia. The core conversion to LEU is being performed with financial support from the U. S. government. In the framework of non-proliferation policies, the international community presently aims to minimize the amount of nuclear material available that could be used for nuclear weapons. In this geopolitical context most research and test reactors, both domestic and international, have started a program of conversion to the use of LEU fuel. A new type of LEU fuel based on an alloy of uranium and molybdenum (U-Mo) is expected to allow the conversion of U.S. domestic high performance reactors like MURR. This report presents the results of a study of core behavior under a set of accident conditions for MURR cores fueled with HEU U-Alx dispersion fuel or LEU monolithic U-Mo alloy fuel with 10 wt% Mo (U-10Mo).« less

Development of undergraduate nuclear security curriculum at College of Engineering, Universiti Tenaga Nasional

NASA Astrophysics Data System (ADS)

Hamid, Nasri A.; Mujaini, Madihah; Mohamed, Abdul Aziz

2017-01-01

The Center for Nuclear Energy (CNE), College of Engineering, Universiti Tenaga Nasional (UNITEN) has a great responsibility to undertake educational activities that promote developing human capital in the area of nuclear engineering and technology. Developing human capital in nuclear through education programs is necessary to support the implementation of nuclear power projects in Malaysia in the near future. In addition, the educational program must also meet the nuclear power industry needs and requirements. In developing a certain curriculum, the contents must comply with the university's Outcomes Based Education (OBE) philosophy. One of the important courses in the nuclear curriculum is in the area of nuclear security. Basically the nuclear security course covers the current issues of law, politics, military strategy, and technology with regard to weapons of mass destruction and related topics in international security, and review legal regulations and political relationship that determine the state of nuclear security at the moment. In addition, the course looks into all aspects of the nuclear safeguards, builds basic knowledge and understanding of nuclear non-proliferation, nuclear forensics and nuclear safeguards in general. The course also discusses tools used to combat nuclear proliferation such as treaties, institutions, multilateral arrangements and technology controls. In this paper, we elaborate the development of undergraduate nuclear security course at the College of Engineering, Universiti Tenaga Nasional. Since the course is categorized as mechanical engineering subject, it must be developed in tandem with the program educational objectives (PEO) of the Bachelor of Mechanical Engineering program. The course outcomes (CO) and transferrable skills are also identified. Furthermore, in aligning the CO with program outcomes (PO), the PO elements need to be emphasized through the CO-PO mapping. As such, all assessments and distribution of Bloom Taxonomy levels are assigned in accordance with the CO-PO mapping. Finally, the course has to fulfill the International Engineering Alliance (IEA) Graduate Attributes of the Washington Accord.

Oral biology in middle age: a history of the University at Buffalo Oral Biology PhD Program.

PubMed

Scannapieco, F A

2014-05-01

In 1960, the first Department of Oral Biology in the United States dedicated to the conduct of research, graduate biomedical research education, and the provision of basic oral science education for the DDS curriculum was established at the University at Buffalo. In 1963, the Department organized the first PhD Program in Oral Biology in the United States. This PhD program has produced a large cadre of oral health researchers, many of whom have gone on to make major contributions to dental research and education. This article provides a brief history of the program, the context within which the program was organized and developed, and a description of some of the many faculty, students, and fellows associated with the program. Additionally, to celebrate the 50th anniversary of this program, a symposium, entitled "The Oral Microbiome, Immunity and Chronic Disease", was held on June 12-14, 2013, in Buffalo, New York. The proceedings are published online in Advances in Dental Research (2014, Vol. 26).

Exemplary Programs in Secondary School Biology.

ERIC Educational Resources Information Center

McComas, William F.; Penick, John E.

1989-01-01

Summarizes 10 exemplary programs which address topics on individualized biology, a modified team approach, limnology, physical anthropology, the relevance of biology to society, ecology, and health. Provides names and addresses of contact persons for further information. Units cover a broad range of abilities and activities. (RT)

Environmental Biology Programs at the University of Illinois, Urbana-Champaign.

ERIC Educational Resources Information Center

Getz, Lowell L.

1987-01-01

Describes the programs of the Department of Ecology, Ethology, and Evolution at the University of Illinois (Urbana-Champaign). Focuses on the graduate degrees offered in environmental biology. Lists research interests and courses in plant biology, entomology, forestry, civil engineering, and landscape architecture. (TW)

Pandora’s Box: The Key to Close It

DTIC Science & Technology

1995-01-01

security interests. Current nonproliferation efforts have failed to deter nations from seeclng and ootaining WJ- D . Evidenced by discoveries in Iraq and...acversary wA0 aiso Chllders 7 believes in seecing a X& D -free resolution. Preemptive strikes and defensive shields rely on the U.S. developing complete...the specter of ’nuclear winter’.. .perceptions of strategic leverage had to be dramatically adlusted." ( Moffis -,: 6-7; Nitze: 152: A paradox has

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antolak, Arlyn J.

Particle accelerators play a key role in a broad set of defense and security applications including war-fighter and asset protection, cargo inspection, nonproliferation, materials characterization and stockpile stewardship. Accelerators can replace the high activity radioactive sources that pose a security threat for developing a radiological dispersal device and be used to produce isotopes for medical, industrial, and re-search purposes. Lastly, we present an overview of current and emerging accelerator technologies relevant to addressing the needs of defense and security.

Arms Control and Nonproliferation: A Catalog of Treaties and Agreements

DTIC Science & Technology

2010-02-02

Russia, partly in response to U.S. plans to deploy a missile defense radar in the Czech Republic and interceptor missiles in Poland, stated that it...10 interceptors based in Poland and a radar in the Czech Republic . Russia’s former President Putin and his successor, Vladimir Medvedev, argued that...States reversed its plan to emplace GMD facilities in Poland and the Czech Republic . Congress resisted the Bush Administration’s request for funding

Tracking Next-Generation Automatic Identification Technology (AIT) into 2035

DTIC Science & Technology

2010-04-01

Non-proliferation and Treaty inspections  Shielding / EMI issues  Security/Integrity/Encryption  Taiwan Shipment Fact Sheet http...followed the technical data, but had no idea that they had a live nuclear warhead. While the nuclear ALCM was loaded on the munitions trailer , the...three-man team continued to assemble the other seven ALCMs. As the end of shift neared, all eight ALCMs were loaded on the munitions trailers and the

Nonproliferation vs. Industrial Competitiveness: U.S. Export Controls and the Dual-Use Machine Tool Industry

DTIC Science & Technology

1995-06-01

Economic Foundations of the Next Security System, Berkeley Roundtable on the International Economy (BRIE), (Oxford: Oxford University Press , 1992), pp...former Eastern bloc." 9Michael Mastanduno, Economic Containment: COCOM and the Politics of East-West Trade. (Ithaca: Cornell University Press , 1992...Environment (Washington, DC: National Academy Press , 1991), pp. 61-105. ŕOTA, 1994, p. 49. 6 The United States participates in several multilateral regimes

A Nuclear Energy Renaissance: Challenges to Nuclear Weapon Nonproliferation

DTIC Science & Technology

2009-03-30

carbon dioxide every second.12 Nuclear energy is currently the only energy source capable of significant expansion to replace the many terawatts of...environmental lobby, which for decades opposed nuclear power, has now to a significant part come to support it as an important answer to reduce carbon ...power produced by burning fossil fuels. The 4 likely addition of carbon emission taxes and tax credits will only make nuclear power more economically

Arms Control and Nonproliferation: A Catalog of Treaties and Agreements

DTIC Science & Technology

2007-01-29

U.S. security concerns. The United States and Soviet Union began to sign agreements limiting their strategic offensive nuclear weapons in the early...Russian relationship. At the same time, however, the two sides began to cooperate on securing and eliminating Soviet-era nuclear , chemical, and...the former Soviet Union. The United States is also a leader of an international regime that attempts to limit the spread of nuclear weapons. This

Arms Control and Nonproliferation Technologies, First Quarter 1994

DTIC Science & Technology

1994-01-01

earthquake show detectable signals PATWINGSPAC, U.S. Navy, (3) an array of the U.S. for magnitude 3 events at 320-360 kilometers. Initial Navy SOSUS system...30 explosions shots, in generating seismic signals at regional or greater than 50 tons, including one shot greater than teleseismic distances). These... general Rainier Mesa earthquakes from Rock Valley at NTS appear to be events (Area 12) of roughly the same yield had signif- intermediate between the

Moving Beyond Pretense: Nuclear Power and Nonproliferation

DTIC Science & Technology

2014-06-01

and Hezbollah, might be at a heightened risk of transfer- ring nuclear weapons to terrorists. Moreover, even if no state would ever intentionally...programs—basically IAEA inspections and ex- port controls—we seem to be slipping into reliance on greatly increased national intelligence operations, both...generators, turbine , piping, and other large equipment needed for the system. • By 2008: A total of 82 megatons of fuel enriched up to 3.62 percent U

Current and Future Challenges for Asian Nonproliferation Export Controls: A Regional Response

DTIC Science & Technology

2004-10-01

degree of financial interdependence was evidenced by the 1997 financial crisis, which resulted in the Chiang Mai + 3 Initiative.ř Intra-company trade...financial crisis, the finance ministers of ASEAN+3 countries (China, Japan, and South Korea) reached agreement on the " Chiang Mai Initiative," which...stability. The Chiang Mai Initiative has contributed to improving exchange rate stability and in doing so may also have contributed to closer regional

Cruise Missile Penaid Nonproliferation: Hindering the Spread of Countermeasures Against Cruise Missile Defenses

DTIC Science & Technology

2014-01-01

this report treats cruise missile penaids and UAV penaids, sometimes called “self-protection” (see La Franchi , 2004), interchangeably. 8 Cruise...Penaid Export Controls 41 2. Anti-Jam Equipment MTCR Item 11.A.3.b.3 (Avionics): Current text: “Receiving equipment for Global Navigation Satellite...subsystems beyond those for global navigation satellite systems to all sensor, navigation, and communications systems, and add “including multi-mode

Export Controls and Nonproliferation Policy

DTIC Science & Technology

1994-05-01

Export Control Classification Numbers ( ECCNs ). The ECCNs do not correspond one-for-one to single commodity technology, or software items: in some...cases an ECCN covers only a single, narrowly defined item, but in many cases multiple related items fall under the same ECCN . The reason for control of...each ECCN category may be single or multiple (e.g., for both National Security and Nuclear Proliferation) but the reason(s) listed may in fact apply

Bombs and Umbrellas: Defending US Middle East Allies from a Nuclear-Armed Iran

DTIC Science & Technology

2010-05-01

Robert Jervis, “Deterrence Theory Revisited,” World Politics 31, no. 2 (January 1979), 299. 28 Ibid.. 29 Morgan, 14. 9 nuclear conflagration .30...world to conflagration which could spread beyond control.”80 At the same time, Chiang‟s backers inside the United States kept the pressure on the...produced few concrete results.90 After numerous starts and stops, North Korea eventually abandoned the agreement, left the Nuclear Nonproliferation

Strengthened IAEA Safeguards-Imagery Analysis: Geospatial Tools for Nonproliferation Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pabian, Frank V

2012-08-14

This slide presentation focuses on the growing role and importance of imagery analysis for IAEA safeguards applications and how commercial satellite imagery, together with the newly available geospatial tools, can be used to promote 'all-source synergy.' As additional sources of openly available information, satellite imagery in conjunction with the geospatial tools can be used to significantly augment and enhance existing information gathering techniques, procedures, and analyses in the remote detection and assessment of nonproliferation relevant activities, facilities, and programs. Foremost of the geospatial tools are the 'Digital Virtual Globes' (i.e., GoogleEarth, Virtual Earth, etc.) that are far better than previouslymore » used simple 2-D plan-view line drawings for visualization of known and suspected facilities of interest which can be critical to: (1) Site familiarization and true geospatial context awareness; (2) Pre-inspection planning; (3) Onsite orientation and navigation; (4) Post-inspection reporting; (5) Site monitoring over time for changes; (6) Verification of states site declarations and for input to State Evaluation reports; and (7) A common basis for discussions among all interested parties (Member States). Additionally, as an 'open-source', such virtual globes can also provide a new, essentially free, means to conduct broad area search for undeclared nuclear sites and activities - either alleged through open source leads; identified on internet BLOGS and WIKI Layers, with input from a 'free' cadre of global browsers and/or by knowledgeable local citizens (a.k.a.: 'crowdsourcing'), that can include ground photos and maps; or by other initiatives based on existing information and in-house country knowledge. They also provide a means to acquire ground photography taken by locals, hobbyists, and tourists of the surrounding locales that can be useful in identifying and discriminating between relevant and non-relevant facilities and their associated infrastructure. The digital globes also provide highly accurate terrain mapping for better geospatial context and allow detailed 3-D perspectives of all sites or areas of interest. 3-D modeling software (i.e., Google's SketchUp6 newly available in 2007) when used in conjunction with these digital globes can significantly enhance individual building characterization and visualization (including interiors), allowing for better assessments including walk-arounds or fly-arounds and perhaps better decision making on multiple levels (e.g., the best placement for International Atomic Energy Agency (IAEA) video monitoring cameras).« less

Evolution of Aging Theories: Why Modern Programmed Aging Concepts Are Transforming Medical Research.

PubMed

Goldsmith, Theodore C

2016-12-01

Programmed aging refers to the idea that senescence in humans and other organisms is purposely caused by evolved biological mechanisms to obtain an evolutionary advantage. Until recently, programmed aging was considered theoretically impossible because of the mechanics of the evolution process, and medical research was based on the idea that aging was not programmed. Theorists struggled for more than a century in efforts to develop non-programmed theories that fit observations, without obtaining a consensus supporting any non-programmed theory. Empirical evidence of programmed lifespan limitations continued to accumulate. More recently, developments, especially in our understanding of biological inheritance, have exposed major issues and complexities regarding the process of evolution, some of which explicitly enable programmed aging of mammals. Consequently, science-based opposition to programmed aging has dramatically declined. This progression has major implications for medical research, because the theories suggest that very different biological mechanisms are ultimately responsible for highly age-related diseases that now represent most research efforts and health costs. Most particularly, programmed theories suggest that aging per se is a treatable condition and suggest a second path toward treating and preventing age-related diseases that can be exploited in addition to the traditional disease-specific approaches. The theories also make predictions regarding the nature of biological aging mechanisms and therefore suggest research directions. This article discusses developments of evolutionary mechanics, the consequent programmed aging theories, and logical inferences concerning biological aging mechanisms. It concludes that major medical research organizations cannot afford to ignore programmed aging concepts in assigning research resources and directions.

A BSCS-Style Laboratory Approach for University General Biology.

ERIC Educational Resources Information Center

Leonard, William H.

1982-01-01

Compared effectiveness of a Biological Sciences Curriculum Study (BSCS)-style laboratory program in a university general biology course against a popular traditionally oriented program. Although learning gains for both groups were significant, students using the BSCS-style investigations scored significantly higher on a posttest of laboratory…

Classical Biological Control of Invasive Legacy Crop Pests: New Technologies Offer Opportunities to Revisit Old Pest Problems in Perennial Tree Crops

PubMed Central

Hoddle, Mark S.; Warner, Keith; Steggall, John; Jetter, Karen M.

2014-01-01

Advances in scientific disciplines that support classical biological control have provided “new tools” that could have important applications for biocontrol programs for some long-established invasive arthropod pests. We suggest that these previously unavailable tools should be used in biological control programs targeting “legacy pests”, even if they have been targets of previously unsuccessful biocontrol projects. Examples of “new tools” include molecular analyses to verify species identities and likely geographic area of origin, climate matching and ecological niche modeling, preservation of natural enemy genetic diversity in quarantine, the use of theory from invasion biology to maximize establishment likelihoods for natural enemies, and improved understanding of the interactions between natural enemy and target pest microbiomes. This review suggests that opportunities exist for revisiting old pest problems and funding research programs using “new tools” for developing biological control programs for “legacy pests” could provide permanent suppression of some seemingly intractable pest problems. As a case study, we use citricola scale, Coccus pseudomagnoliarum, an invasive legacy pest of California citrus, to demonstrate the potential of new tools to support a new classical biological control program targeting this insect. PMID:26463063

BioBlocks: Programming Protocols in Biology Made Easier.

PubMed

Gupta, Vishal; Irimia, Jesús; Pau, Iván; Rodríguez-Patón, Alfonso

2017-07-21

The methods to execute biological experiments are evolving. Affordable fluid handling robots and on-demand biology enterprises are making automating entire experiments a reality. Automation offers the benefit of high-throughput experimentation, rapid prototyping, and improved reproducibility of results. However, learning to automate and codify experiments is a difficult task as it requires programming expertise. Here, we present a web-based visual development environment called BioBlocks for describing experimental protocols in biology. It is based on Google's Blockly and Scratch, and requires little or no experience in computer programming to automate the execution of experiments. The experiments can be specified, saved, modified, and shared between multiple users in an easy manner. BioBlocks is open-source and can be customized to execute protocols on local robotic platforms or remotely, that is, in the cloud. It aims to serve as a de facto open standard for programming protocols in Biology.

The NASA planetary biology internship experience

NASA Technical Reports Server (NTRS)

Hinkle, G.; Margulis, L.

1991-01-01

By providing students from around the world with the opportunity to work with established scientists in the fields of biogeochemistry, remote sensing, and origins of life, among others, the NASA Planetary Biology Internship (PBI) Program has successfully launched many scientific careers. Each year approximately ten interns participate in research related to planetary biology at NASA Centers, NASA-sponsored research in university laboratories, and private institutions. The PBI program also sponsors three students every year in both the Microbiology and Marine Ecology summer courses at the Marine Biological Laboratory. Other information about the PBI Program is presented including application procedure.

The Simulation and Analysis of an Evolutionary Model of Deoxyribonucleic Acid (DNA).

DTIC Science & Technology

1983-09-01

current interest in evolutionary biology . This section identifies the organization of the remainder of the paper. The second chapter reports the...the field of evolutionary biology . 77 APPENDIX 78 APPENDIX A PROGRAM SOURCE LISTING -79 PROGRAM SOURCE LISTING 00005 PROGRAM (COMPUTERANDOM MUTATIONS...34Some Theoretical Aspects of the Problem of Life Origin," Journal 2f Theoreical Biology : 13-23, 1975. 27. Chirpich, Thomas P. "Rates of Protein

78 FR 8128 - Request for Nominations of Experts to the EPA Office of Research and Development's Board of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-05

... Program; Homeland Security Research Program; Human Health Risk Assessment Research Program; Safe and... --atmospheric physics Biology --biogeochemistry --cell biology --endocrinology (endocrine disruptors... analysis --uncertainty analysis Nanotechnology Public Health --children's health --community health...

BASIC Simulation Programs; Volumes I and II. Biology, Earth Science, Chemistry.

ERIC Educational Resources Information Center

Digital Equipment Corp., Maynard, MA.

Computer programs which teach concepts and processes related to biology, earth science, and chemistry are presented. The seven biology problems deal with aspects of genetics, evolution and natural selection, gametogenesis, enzymes, photosynthesis, and the transport of material across a membrane. Four earth science problems concern climates, the…

Authorized Course of Instruction for the Quinmester Program. Science: Cell Biology, Introduction to Life Science.

ERIC Educational Resources Information Center

Dade County Public Schools, Miami, FL.

This instructional package contains two biological units developed for the Dade County Florida Quinmester Program. "Introduction to Life Sciences" develops student understandings of cell structure and function, and compares different levels of cellular organization. "Cell Biology" investigates the origin of modern cellular…

Extended Deterrence, Nuclear Proliferation, and START III

DOE Office of Scientific and Technical Information (OSTI.GOV)

Speed, R.D.

2000-06-20

Early in the Cold War, the United States adopted a policy of ''extended nuclear deterrence'' to protect its allies by threatening a nuclear strike against any state that attacks these allies. This threat can (in principle) be used to try to deter an enemy attack using conventional weapons or one using nuclear, chemical, or biological weapons. The credibility of a nuclear threat has long been subject to debate and is dependent on many complex geopolitical factors, not the least of which is the military capabilities of the opposing sides. The ending of the Cold War has led to a significantmore » decrease in the number of strategic nuclear weapons deployed by the United States and Russia. START II, which was recently ratified by the Russian Duma, will (if implemented) reduce the number deployed strategic nuclear weapons on each side to 3500, compared to a level of over 11,000 at the end of the Cold War in 1991. The tentative limit established by Presidents Clinton and Yeltsin for START III would reduce the strategic force level to 2000-2500. However, the Russians (along with a number of arms control advocates) now argue that the level should be reduced even further--to 1500 warheads or less. The conventional view is that ''deep cuts'' in nuclear weapons are necessary to discourage nuclear proliferation. Thus, as part of the bargain to get the non-nuclear states to agree to the renewal of the Nuclear Non-Proliferation Treaty, the United States pledged to work towards greater reductions in strategic forces. Without movement in the direction of deep cuts, it is thought by many analysts that some countries may decide to build their own nuclear weapons. Indeed, this was part of the rationale India used to justify its own nuclear weapons program. However, there is also some concern that deep cuts (to 1500 or lower) in the U.S. strategic nuclear arsenal could have the opposite effect. The fear is that such cuts might undermine extended deterrence and cause a crisis in confidence among U.S. allies to such an extent that they could seek nuclear weapons of their own to protect themselves.« less

Breaking down Barriers: A Bridge Program Helps First-Year Biology Students Connect with Faculty

ERIC Educational Resources Information Center

Cooper, Katelyn M.; Ashley, Michael; Brownell, Sara E.

2018-01-01

Summer bridge programs often aim to build social connections for first-year students to ease their transition into college, yet few studies have reported on bridge programs successfully leading to these outcomes. We backward designed a summer bridge program for incoming biology majors to increase the comfort and connections among students and…

Life sciences flight experiments program - Overview

NASA Technical Reports Server (NTRS)

Berry, W. E.; Dant, C. C.

1981-01-01

The considered LSFE program focuses on Spacelab life sciences missions planned for the 1984-1985 time frame. Life Sciences Spacelab payloads, launched at approximately 18-months intervals, will enable scientists to test hypotheses from such disciplines as vestibular physiology, developmental biology, biochemistry, cell biology, plant physiology, and a variety of other life sciences. An overview is presented of the LSFE program that will take advantage of the unique opportunities for biological experimentation possible on Spacelab. Program structure, schedules, and status are considered along with questions of program selection, and the science investigator working groups. A description is presented of the life sciences laboratory equipment program, taking into account the general purpose work station, the research animal holding facility, and the plant growth unit.

Toward synthesizing executable models in biology.

PubMed

Fisher, Jasmin; Piterman, Nir; Bodik, Rastislav

2014-01-01

Over the last decade, executable models of biological behaviors have repeatedly provided new scientific discoveries, uncovered novel insights, and directed new experimental avenues. These models are computer programs whose execution mechanistically simulates aspects of the cell's behaviors. If the observed behavior of the program agrees with the observed biological behavior, then the program explains the phenomena. This approach has proven beneficial for gaining new biological insights and directing new experimental avenues. One advantage of this approach is that techniques for analysis of computer programs can be applied to the analysis of executable models. For example, one can confirm that a model agrees with experiments for all possible executions of the model (corresponding to all environmental conditions), even if there are a huge number of executions. Various formal methods have been adapted for this context, for example, model checking or symbolic analysis of state spaces. To avoid manual construction of executable models, one can apply synthesis, a method to produce programs automatically from high-level specifications. In the context of biological modeling, synthesis would correspond to extracting executable models from experimental data. We survey recent results about the usage of the techniques underlying synthesis of computer programs for the inference of biological models from experimental data. We describe synthesis of biological models from curated mutation experiment data, inferring network connectivity models from phosphoproteomic data, and synthesis of Boolean networks from gene expression data. While much work has been done on automated analysis of similar datasets using machine learning and artificial intelligence, using synthesis techniques provides new opportunities such as efficient computation of disambiguating experiments, as well as the ability to produce different kinds of models automatically from biological data.

Who's Who in Biology.

ERIC Educational Resources Information Center

Norman, Colin

1983-01-01

Provides top-rated programs (by university) in biochemistry, botany, cellular/molecular biology, microbiology, physiology, and zoology. Overall scores included with each program were obtained from 1,848 biologists who were asked to rate programs in terms of faculty quality and their effectiveness in educating graduate students. (Author/JN)

Computerized bioterrorism education and training for nurses on bioterrorism attack agents.

PubMed

Nyamathi, Adeline M; Casillas, Adrian; King, Major L; Gresham, Louise; Pierce, Elaine; Farb, Daniel; Wiechmann, Carrie; Weichmann, Carrie

2010-08-01

Biological agents have the ability to cause large-scale mass casualties. For this reason, their likely use in future terrorist attacks is a concern for national security. Recent studies show that nurses are ill prepared to deal with agents used in biological warfare. Achieving a goal for bioterrorism preparedness is directly linked to comprehensive education and training that enables first-line responders such as nurses to diagnose infectious agents rapidly. The study evaluated participants' responses to biological agents using a computerized bioterrorism education and training program versus a standard bioterrorism education and training program. Both programs improved participants' ability to complete and solve case studies involving the identification of specific biological agents. Participants in the computerized bioterrorism education and training program were more likely to solve the cases critically without reliance on expert consultants. However, participants in the standard bioterrorism education and training program reduced the use of unnecessary diagnostic tests.

Publications of the planetary biology program for 1975: A special bibliography. [on NASA programs and research projects on extraterrestrial life

NASA Technical Reports Server (NTRS)

Souza, K. A. (Compiler); Young, R. S. (Compiler)

1976-01-01

The Planetary Biology Program of the National Aeronautics and Space Administration is the first and only integrated program to methodically investigate the planetary events which may have been responsible for, or related to, the origin, evolution, and distribution of life in the universe. Research supported by this program is divided into the seven areas listed below: (1) chemical evolution, (2) organic geochemistry, (3) life detection, (4) biological adaptation, (5) bioinstrumentation, (6) planetary environments, and (7) origin of life. The arrangement of references in this bibliography follows the division of research described above. Articles are listed alphabetically by author under the research area with which they are most closely related. Only those publications which resulted from research supported by the Planetary Biology Program and which bear a 1975 publication date have been included. Abstracts and theses are not included because of the preliminary and abbreviated nature of the former and the frequent difficulty of obtaining the latter.

Particle-In-Cell Modeling For MJ Dense Plasma Focus with Varied Anode Shape

NASA Astrophysics Data System (ADS)

Link, A.; Halvorson, C.; Schmidt, A.; Hagen, E. C.; Rose, D.; Welch, D.

2014-10-01

Megajoule scale dense plasma focus (DPF) Z-pinches with deuterium gas fill are compact devices capable of producing 1012 neutrons per shot but past predictive models of large-scale DPF have not included kinetic effects such as ion beam formation or anomalous resistivity. We report on progress of developing a predictive DPF model by extending our 2D axisymmetric collisional kinetic particle-in-cell (PIC) simulations to the 1 MJ, 2 MA Gemini DPF using the PIC code LSP. These new simulations incorporate electrodes, an external pulsed-power driver circuit, and model the plasma from insulator lift-off through the pinch phase. The simulations were performed using a new hybrid fluid-to-kinetic model transitioning from a fluid description to a fully kinetic PIC description during the run-in phase. Simulations are advanced through the final pinch phase using an adaptive variable time-step to capture the fs and sub-mm scales of the kinetic instabilities involved in the ion beam formation and neutron production. Results will be present on the predicted effects of different anode configurations. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory (LLNL) under Contract DE-AC52-07NA27344 and supported by the Laboratory Directed Research and Development Program (11-ERD-063) and the Computing Grand Challenge program at LLNL. This work supported by Office of Defense Nuclear Nonproliferation Research and Development within U.S. Department of Energy's National Nuclear Security Administration.

Managing the Nuclear Fuel Cycle: Policy Implications of Expanding Global Access to Nuclear Power

DTIC Science & Technology

2008-09-03

Spent nuclear fuel disposal has remained the most critical aspect of the nuclear fuel cycle for the United States, where longstanding nonproliferation...inalienable right and by and large, neither have U.S. government officials. However, the case of Iran raises perhaps the most critical question in...the enrichment process can take advantage of the slight difference in atomic mass between 235U and 238U. The typical enrichment process requires

Managing the Nuclear Fuel Cycle: Policy Implications of Expanding Global Access to Nuclear Power

DTIC Science & Technology

2010-03-05

However, the case of Iran raises perhaps the most critical question in this decade for strengthening the nuclear nonproliferation regime: How can...enrichment process can take advantage of the slight difference in atomic mass between 235U and 238U. The typical enrichment process requires about 10 lbs of...neutrons but can induce fission in all actinides , including all plutonium isotopes. Therefore, nuclear fuel for a fast reactor must have a higher

Managing the Nuclear Fuel Cycle: Policy Implications of Expanding Global Access to Nuclear Power

DTIC Science & Technology

2008-01-20

critical aspect of the nuclear fuel cycle for the United States, where longstanding nonproliferation policy discouraged commercial nuclear fuel...have U.S. government officials. However, the case of Iran raises perhaps the most critical question in this decade for strengthening the nuclear...slight difference in atomic mass between 235U and 238U. The typical enrichment process requires about 10 lbs of uranium U3O8 to produce 1 lb of low

Detection of Nuclear Weapons and Materials: Science, Technologies, Observations

DTIC Science & Technology

2008-11-06

Nonproliferation Studies , 2004; Michael Levi, On Nuclear Terrorism, Cambridge, MA, Harvard University Press, 2007; and Carson Mark et al., “Can Terrorists Build...radiation and types of shielding. A DMOA study of real-world data found that the spectra from cargo differed between spring-summer and fall-winter; the study ...Algorithm and Resolution Studies ,” LLNL-TR-401531, December 31, 2007, by Padmini Sokkappa et al., pp. 21-22 This source is a report marked by Lawrence