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Sample records for blue mountains eye

  1. Sensory impairment and driving: the Blue Mountains Eye Study.

    PubMed Central

    Ivers, R Q; Mitchell, P; Cumming, R G

    1999-01-01

    OBJECTIVES: This study examined the associations between vision, hearing, loss, and car accidents. METHODS: A cross-sectional survey of 3654 people aged 49 years and older in the Blue Mountains, Australia, was used. Each subject had a detailed eye examination and interview. RESULTS: Self-reported car accident rates in the past year among 2379 current drivers were 5.6% for those aged 49 to 79 years and 9.1% for those 80 years and older. A 2-line difference in visual acuity was associated with increased risk of accidents (adjusted prevalence ratio [PR] = 1.6), as was visual acuity worse than 6/18 in the right eye (PR = 2.0), overall moderate hearing loss (PR = 1.9), and hearing loss in the right ear (PR = 1.8). CONCLUSIONS: Sensory loss in drivers may be an important risk factor for car accidents. PMID:9987472

  2. Association of open-angle glaucoma loci with incident glaucoma in the Blue Mountains Eye Study.

    PubMed

    Burdon, Kathryn P; Mitchell, Paul; Lee, Anne; Healey, Paul R; White, Andrew J R; Rochtchina, Elena; Thomas, Peter B M; Wang, Jie Jin; Craig, Jamie E

    2015-01-01

    To determine if open-angle glaucoma (OAG)-associated single nucleotide polymorphisms (SNPs) are associated with incident glaucoma and if such genetic information is useful in OAG risk prediction. Case-control from within a population-based longitudinal study. study population: Individuals aged over 49 years of age living in the Blue Mountains region west of Sydney and enrolled in the Blue Mountains Eye Study. observation: Cases for this sub-study (n = 67) developed incident OAG between baseline and 10-year visits, in either eye, while controls (n = 1919) had no evidence for OAG at any visit. All participants had an ocular examination and DNA genotyped for reported OAG risk SNPs. main outcome measure: Incident OAG. Two loci also known to be associated with cup-to-disc ratio as well as OAG (9p21 near CDKN2B-AS1 and SIX1/SIX6) were both significantly associated with incident OAG in the Blue Mountains Eye Study cohort (P = .006 and P = .004, respectively). The TMCO1 locus was nominally associated (P = .012), while the CAV1/CAV2 and 8q22 loci were not associated. Multivariate logistic regression and neural network analysis both indicated that the genetic risk factors contributed positively to the predictive models incorporating traditional risk factors. This study shows that previously reported genetic variations related to OAG and cup-to-disc ratio are associated with the onset of OAG and thus may become useful in risk prediction algorithms designed to target early treatment to those most at risk of developing glaucoma. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Iris color, skin sun sensitivity, and age-related maculopathy. The Blue Mountains Eye Study.

    PubMed

    Mitchell, P; Smith, W; Wang, J J

    1998-08-01

    The purpose of the study was to assess relationships between age-related maculopathy (ARM) and iris color, skin sun sensitivity, and other sunlight-related factors. Cross-sectional population-based study. The Blue Mountains Eye Study performed a detailed eye examination of 3654 residents living in the Blue Mountains area, west of Sydney, Australia. Subjects with late age-related macular degeneration (late AMD), early ARM, and large drusen (> or = 125 microns diameter) were identified using masked grading of retinal photographs. Iris color was graded using standard photographs, and interviewers collected questionnaire data on sunlight-related factors. Logistic regression, adjusting for age, sex, AMD family history, and current smoking, was used to assess associations. Blue iris color was significantly associated with an increased risk of both late AMD (odds ratio [OR], 1.69) and early ARM (OR, 1.45). An increased risk of late AMD, but not early ARM, was associated with both high (OR, 2.54) and low (OR, 2.18) skin sun sensitivity, as assessed using the Fitzpatrick sun-sensitivity scale. These associations remained after adjusting for the presence of sun-related skin damage. Neither history (or treatment) of skin cancer lesions, signs of sun-induced skin damage, or number of severe sunburns was associated with either late AMD or early ARM. Blue iris color was associated with an increased risk of both late AMD and early ARM in this population. Abnormal skin sensitivity to sunlight was also associated with an increased risk of late AMD.

  4. Effects of caffeine on intraocular pressure: the Blue Mountains Eye Study.

    PubMed

    Chandrasekaran, Sujatha; Rochtchina, Elena; Mitchell, Paul

    2005-12-01

    To examine the relationship between coffee and caffeine intakes and intraocular pressure (IOP). The Blue Mountains Eye Study examined 3654 participants aged 49+ years in an area west of Sydney, Australia. A detailed medical history questionnaire included average daily intakes of coffee and tea. The eye examination included Goldmann applanation tonometry and automated perimetry. Participants using glaucoma medications or who had previous cataract or glaucoma surgery or signs of pigmentary glaucoma/pigment dispersion, were excluded. Mean and maximum IOP calculations were used. Participants with open-angle glaucoma (OAG) who reported regular coffee drinking had significantly higher mean IOP (19.63 mm Hg) than participants who said that they did not drink coffee (16.84 mm Hg), after multivariate adjustment, P = 0.03. Participants consuming > or = 200 mg caffeine per day had higher mean IOP (19.47 mm Hg) than those consuming < 200 mg caffeine per day (17.11 mm Hg), after adjusting for age, sex, and systolic blood pressure (SBP), P = 0.06. This association did not reach statistical significance after multivariate adjustment. No association between coffee or caffeine consumption and higher IOP was found in participants with ocular hypertension (OH) and those without open-angle glaucoma. In participants with open-angle glaucoma, this study identified a positive cross-sectional association between coffee consumption/higher caffeine intakes and elevated intraocular pressure.

  5. Estimation of Flavonoid Intake in Older Australians: Secondary Data Analysis of the Blue Mountains Eye Study.

    PubMed

    Kent, Katherine; Charlton, Karen E; Russell, Joanna; Mitchell, Paul; Flood, Victoria M

    2015-01-01

    Flavonoids, consumed in plant-based foods, have been linked to risk reduction of cancers, cardiovascular, and neurodegenerative diseases. The paucity of information on dietary sources and quantities of flavonoid intake in older adults limits interpretation of epidemiological studies that link flavonoid intake with health outcomes in this population. It was our aim to describe total flavonoid intake, including flavonoid subclasses, in older Australians and to identify rich and commonly consumed sources of flavonoids in this age group. Twelve days of weighed food record dietary data from a subsample of the Blue Mountains Eye Study baseline cohort study of older Australians (n = 79) was analyzed using the US Department of Agriculture flavonoid database. Mean intake of flavonoids was estimated to be 683 mg/day (SD = 507) of which flavan-3-ols contributed 92%, followed by flavonols (4%), flavanones (3%), and flavones (<1%). Black tea was the major flavonoid source, providing 89% of total flavonoid intake. No differences in intake between genders were identified. Dietary intake of flavonoids and flavonoid subclasses in older Australians is similar to the one other estimation of intake in Australian older adults and confirms the types of foods that contribute to flavonoid intake among this sample of older Australians.

  6. The Q368STOP myocilin mutation in a population-based cohort: the Blue Mountains Eye Study.

    PubMed

    Baird, Paul N; Richardson, Andrea J; Craig, Jamie E; Rochtchina, Elena; Mackey, David A; Mitchell, Paul

    2005-06-01

    To investigate the prevalence of the Q368STOP myocilin mutation in a population-based cohort: the Blue Mountains Eye Study (BMES). Population-based study. DNA was extracted from 2,142 individuals collected through the BMES, including 31 individuals with glaucoma. All individuals were screened for the presence of the Q368STOP mutation of myocilin. Genotyping of the microsatellite markers My5, My3, D1S2815, and D1S1619 was also undertaken. None of the 31 open-angle glaucoma-positive individuals presented with the Q368STOP mutation. However, two individuals (aged 56 and 72) with no clinical signs of OAG, were identified with this mutation. Allele sharing at the four microsatellite markers defining the Q368STOP disease haplotype for OAG was found in these two individuals. The Q368STOP myocilin mutation occurs at a low prevalence (0.09%) in a general, older population.

  7. Symmetry of optic nerve head parameters measured by the heidelberg retina tomograph 3 in healthy eyes: the Blue Mountains Eye study.

    PubMed

    Li, Haitao; Healey, Paul R; Tariq, Yasser M; Teber, Erdahl; Mitchell, Paul

    2013-03-01

    To assess the symmetry of optic nerve head parameters measured by the Heidelberg Retina Tomograph 3 (HRT 3) between fellow eyes in a normal elderly population. Cross-sectional population-based study. Participants of the Blue Mountains Eye Study 10-year follow-up who did not have optic disc disease, including glaucoma, were included. Optic nerve head parameters measured by HRT 3 were compared between fellow eyes. The normal range of interocular asymmetry (larger disc minus smaller disc) was determined by the 2.5th and 97.5th percentiles. A total of 1276 eligible participants had HRT scans of both eyes. HRT measurements in right eyes differed slightly in rim steepness and rim volume from those in left eyes (P < .05). The 2.5th and 97.5th percentile of interocular asymmetry limits were -0.41 and 0.45 for cup-to-disc ratio and -0.19 and 0.22 for cup-to-disc area ratio, respectively. The highest interocular correlation was found in disc area and cup area (r ranged from 0.74-0.76), whereas mean cup depth, cup volume, and retinal nerve fiber layer thickness had the poorest correlation (r ≤ 0.07). Greater optic disc area asymmetry was associated with a larger interocular difference in the other optic nerve head parameters. There was minimal interocular difference and substantial interocular correlation in optic nerve head parameters measured by HRT 3. Interocular asymmetry greater than 0.2 for cup-to-disc area ratio was considered outside the normal range. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. Visual impairment and subsequent use of support services among older people: longitudinal findings from the Blue Mountains Eye Study.

    PubMed

    Hong, Thomas; Mitchell, Paul; Burlutsky, George; Fong, Calvin Sze-Un; Rochtchina, Elena; Wang, Jie Jin

    2013-08-01

    To assess the impact of visual impairment and blindness on the incident use of community support services in the Blue Mountains Eye Study. Population-based cohort. Of 3654 baseline participants (1992-1994), 2334, 1952, and 1149 were re-examined after 5, 10, and 15 years, respectively. Incident visual impairment was defined as subsequent development of visual impairment (visual acuity <20/40) in the better eye of subjects with best-corrected visual acuity ≥20/40 at baseline. Community support service use included regular use of Meals on Wheels, Home Care, or community nurse services. Informal support included assistance from family or friends. Discrete logistic regression models with time-dependent study and outcome variables were used to assess associations between visual impairment and subsequent use of support, adjusted for potential confounders. Among participants with bilateral visual impairment at baseline, incident use of community services over 5-15 years was 41.7% compared to 19.4% in those without visual impairment at baseline (odds ratio, 1.39; 95% confidence interval, 0.54-3.60). Persons with incident bilateral visual impairment were more likely to subsequently need community support (odds ratio, 3.32; confidence interval 1.96-5.59) in 5 years, compared to persons without visual impairment during the entire follow-up period. Baseline older age, walking disability, receiving pension, and having 2+ hospital admissions within 12 months were also significantly associated with incident use of support services. Development of bilateral visual impairment in this cohort was associated with greater likelihood of subsequent use of community or informal support services in 5 years, independent of physical comorbidities. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Complement factor H polymorphisms, renal phenotypes and age-related macular degeneration: the Blue Mountains Eye Study.

    PubMed

    Xing, C; Sivakumaran, T A; Wang, J J; Rochtchina, E; Joshi, T; Smith, W; Mitchell, P; Iyengar, S K

    2008-04-01

    Complement factor H (CFH) is a key regulator of the alternative pathway of complement and its mutations have been associated with membranoproliferative glomerulonephritis type II, atypical hemolytic uremic syndrome and age-related macular degeneration (AMD), suggesting that alternative pathway dysregulation is a common pathogenetic feature of these ocular and renal conditions. In this study we tested the hypothesis that common CFH variants have a global role in renal function in the Australian population-based Blue Mountains Eye Study (BMES). We replicated the association of I62V with estimated glomerular filtration rate (GFR; P=0.017) and creatinine clearance (CRCL; P=0.015). The minor allele of I62V (G) was deleterious: adding one copy of the G allele decreased GFR/CRCL by approximately 0.98 ml min(-1) per 1.73 m(2) (95% confidence interval (CI): 0.97, 0.99). We also replicated the association of Y402H with AMD and provided an unbiased estimate of population attributable risk (PAR). The minor allele of Y402H (C) was deleterious: the odds ratio estimate of CC genotype compared to TT was 1.87 (95% CI: 1.44, 2.45). The PAR of the C allele was estimated as 0.22 (95% CI: 0.15, 0.28). In summary, in the BMES population we confirmed the association between I62V and renal function, as measured by the estimated GFR, plus the association of Y402H with both early- and late-stage AMD.

  10. The Incidence and Progression of Age-Related Macular Degeneration over 15 Years: The Blue Mountains Eye Study.

    PubMed

    Joachim, Nichole; Mitchell, Paul; Burlutsky, George; Kifley, Annette; Wang, Jie Jin

    2015-12-01

    To assess the 15-year incidence and progression of age-related macular degeneration (AMD) in an older Australian population. Population-based cohort study. Blue Mountains Eye Study (BMES) participants (n = 3654) aged 49+ years were examined during 1992-1994. Of these, 2334 (75.8% of survivors) were reexamined after 5 years (1997-1999), 1952 (76.7% of survivors) after 10 years (2002-2004), and 1149 (56.1% of survivors) after 15 years (2007-2010). Color retinal photographs were taken, and comprehensive questionnaires were administered at each visit and DNA was genotyped. Retinal photographic grading was performed by the same graders following the Wisconsin AMD grading protocol. Side-by-side comparisons were used to confirm newly developed AMD lesions. Incidence was estimated using Kaplan-Meier estimates. Associations of AMD incidence with age, sex, smoking status, presence of the complement factor H (CFH)-rs1061170 and age-related maculopathy susceptibility 2 (ARMS2)-rs10490924 polymorphisms, and fish consumption were analyzed using discrete logistic regression models. Generalized estimation equation models were used to assess the risk of incident late AMD associated with baseline AMD lesion characteristics. The 15-year incidence and progression of AMD, and associated factors. The 15-year incidence was 22.7% for early AMD and 6.8% for late AMD. After adjusting for competing risks, early and late AMD incidence were 15.1% and 4.1%, respectively. Age was strongly associated with early and late AMD incidence (both P < 0.0001). After age standardization to the Beaver Dam Eye Study (BDES) population, early and late AMD incidence in the BMES were 13.1% and 3.3%, respectively. Female sex and the presence of both risk alleles of CFH-rs1061170 or ARMS2-rs10490924 were independently associated with early AMD incidence, whereas current smoking and presence of ≥1 risk allele of CFH-rs1061170 or ARMS2-rs10490924 were associated with late AMD incidence. Fish consumption was

  11. Correction of visual impairment by cataract surgery and improved survival in older persons: the Blue Mountains Eye Study cohort.

    PubMed

    Fong, Calvin Sze-un; Mitchell, Paul; Rochtchina, Elena; Teber, Erdahl T; Hong, Thomas; Wang, Jie Jin

    2013-09-01

    We assessed whether correction of visual impairment (VI) by cataract surgery was associated with improved long-term survival in an older Australian population. Population-based cohort study. In the Blue Mountains Eye Study, 354 participants, aged ≥ 49 years, had both cataract and VI or had undergone cataract surgery before baseline examinations. They were subsequently examined after 5- and 10-year follow-ups. Associations between the mortality risk and the surgical correction of VI (visual acuity [VA] <20/40, attributable to cataract) were assessed in Cox proportional hazard regression models, after multivariate adjustment, using time-dependent variables for the study factor. All-cause mortality. The 15-year crude mortality of participants who had undergone cataract surgery at baseline with no subsequent VI (71.8%) was relatively similar to that in participants with cataract-related VI who had not yet undergone surgery (79.4%). However, after adjusting for age and sex, participants who underwent cataract surgery before baseline or during follow-up and no longer had VI had significantly lower long-term mortality risk (hazard ratio [HR], 0.60; 95% confidence interval [CI], 0.46-0.77) than participants with VI due to cataract who had not undergone cataract surgery. This lower mortality risk in the group with surgically corrected VI (HR, 0.54; 95% CI, 0.41-0.73) persisted after further adjustment for smoking, body mass index, home ownership, qualifications, poor self-rated health, the presence of poor mobility, hypertension, diabetes, self-reported history of angina, myocardial infarction, stroke, cancer, asthma, and arthritis. This finding remained significant (HR, 0.55; 95% CI, 0.41-0.73) after additional adjustment for the number of medications taken (continuous variable) and the number (≥ 5 vs. <5) of comorbid conditions (poor mobility, hypertension, diabetes, angina, myocardial infarction, stroke, cancer, asthma, or arthritis) as indicators of frailty

  12. Five-year incidence of age-related maculopathy in relation to iris, skin or hair colour, and skin sun sensitivity: the Blue Mountains Eye Study.

    PubMed

    Wang, Jie Jin; Jakobsen, Kirsten; Smith, Wayne; Mitchell, Paul

    2003-08-01

    This study aimed to assess longitudinal associations between iris,hair and skin colour, plus skin sensitivity to sun and the 5-year incidence of age-related maculopathy (ARM). Of 3654 baseline Blue Mountains Eye Study participants (aged 49+ years), 2335 survivors (75.1%) were re-examined after 5 years. Retinal photographs were graded using the Wisconsin ARM Grading System and incident ARM lesions confirmed using side-by-side grading.Iris/skin/hair colour was assessed and skin sensitivity questions were asked at baseline. After adjusting for age, sex and smoking, no significant associations were found between iris or hair colour and incident late or early ARM. Compared to persons with fair skin, those with very fair skin had an increased risk of developing geographical atrophy (odds ratio [OR] 3.5,95% confidence interval [CI] 1.2-10.4).However, persons with sun-related skin damage were less likely than those without to develop indistinct soft drusen (OR 0.6, 95% CI 0.4-0.9). Longitudinal data provide no support for the previously reported cross-sectional association between iris colour and ARM.

  13. Ol' Blue Eyes, in Focus

    ERIC Educational Resources Information Center

    Nelson, Michael

    2009-01-01

    Scholarly books with "identity" and "culture" in the title have loomed large on academic publishing lists for several years. Scholarly books with "Sinatra" in the title are a more recent phenomenon. Despite his six-decade career as the Voice (the 1940s), the Chairman of the Board (the 50s and 60s), and Ol' Blue Eyes (the 70s through his death, in…

  14. Visual impairment and the incidence of falls and fractures among older people: longitudinal findings from the Blue Mountains Eye Study.

    PubMed

    Hong, Thomas; Mitchell, Paul; Burlutsky, George; Samarawickrama, Chameen; Wang, Jie Jin

    2014-11-04

    We assessed the impact of visual impairment on the incidence of falls and fractures in older persons. Of 3654 baseline participants, 2334, 1952, and 1149 were re-examined after 5, 10, and 15 years. Presenting visual acuity (VA) was measured at each examination. Bilateral and unilateral visual impairment was defined as VA worse than 20/40 in the better and worse eye, respectively. Incident visual impairment was defined in eyes with VA 20/40 or better at baseline, which subsequently developed visual impairment. Incidence of falls was assessed over the 12 months before each visit, whereas incidence of fractures was assessed over the 5 years between two visits. Discrete logistic-regression models with time-dependent variables were used to assess associations between visual impairment and subsequent falls and fractures after adjusting for potential confounding variables. The proportions of participants reporting ≥2 falls ranged between 10% and 14%, and proportions reporting fractures ranged between 12% and 21%, across the three follow-up visits. Participants with incident visual impairment were more likely to report ≥2 falls in 5 years, OR (odds ratio) 1.46, 95% confidence interval (CI) 1.04 to 2.04 (bilateral), and OR 1.22, 95% CI 0.98 to 1.51 (unilateral). Compared to participants with normal vision, those with incident unilateral visual impairment had a higher incidence of fractures over 5 years (OR, 1.27; 95% CI, 0.98-1.51). No increased incidence of falls or fractures was evident after 5+ years among participants with visual impairment. In this older cohort, recent development of visual impairment was associated with increased likelihood of subsequent falls and fractures in the next 5 years, independent of other confounding variables. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

  15. Selection bias from sampling frames: telephone directory and electoral roll compared with door-to-door population census: results from the Blue Mountains Eye Study.

    PubMed

    Smith, W; Mitchell, P; Attebo, K; Leeder, S

    1997-04-01

    Many Australian public health research studies use the telephone directory or the electoral roll as a sampling frame from which to draw study subjects. The sociodemographic, disease-state and risk-factor characteristics of subjects who could be recruited using only the telephone directory or only the electoral roll sampling frames were compared with the characteristics of subjects who would have been missed using only these sampling frames, respectively. In the first phase of the Blue Mountains Eye Study we interviewed and examined 2557 people aged 49 and over living in a defined postcode area, recruited from a door-to-door census. This represented a participation rate of 80.9 per cent and a response rate of 87.9 per cent. The telephone directory was searched for each subject's telephone number and the electoral roll was searched for each subject. Subject characteristics for those who were present in each of these sampling frames were compared with the characteristics of those subjects not included in the sampling frames. The telephone directory listed 2102 (82.2 per cent) of the subjects, and 115 (4.5 per cent) had no telephone connected. The electoral roll contained 2156 (84.3 per cent) of the subjects, and 141 subjects (5.5 per cent) could not be found in either the electoral roll or the telephone directory. Younger subjects, subjects who did not own their own homes and subjects born outside of Australia were significantly less likely to be included in either of these sampling frames. The telephone directory was also more likely to exclude subjects with higher occupational prestige, while the electoral roll was more likely to exclude unmarried persons and males. Researchers using the telephone directory and electoral roll to select subjects for study should be aware of the potential selection bias these sampling frames incur and need to take care when generalising their findings to the wider community.

  16. Trends in added sugar intake and food sources in a cohort of older Australians: 15 years of follow-up from the Blue Mountains Eye Study.

    PubMed

    Moshtaghian, H; Louie, J C Y; Charlton, K E; Probst, Y C; Gopinath, B; Mitchell, P; Flood, V M

    2017-06-01

    The trend of added sugar (AS) intake has not been investigated in the Australian population, including in older adults. The present study aimed to assess trends and food sources of AS intake among a cohort of older Australians during 15 years of follow-up. Dietary data from participants of the Blue Mountains Eye Study (1264 men and 1614 women), aged ≥49 years at baseline, were collected. Dietary intakes were assessed at 5-yearly intervals (1992-94 to 2007-09) using a 145-item food frequency questionnaire (FFQ). AS content of FFQ food items was estimated using a stepwise systematic method. Trends for AS intake between baseline and the three follow-up periods were assessed using linear mixed modelling. In men, the mean (SEM) percentage of energy provided by AS intake (EAS%) declined from 10.4% (0.1%) at baseline to 9.4% (0.2%) at 15-year follow-up (Ptrend = 0.028). Women's mean (SEM) EAS% intake at baseline and 15-year follow-up was 9.2% (0.1%) and 8.8% (0.2%), respectively (Ptrend = 0.550). EAS% intake of men was significantly higher than that of women for 10 years (P < 0.05). Sugar products (table sugar, syrup, jam and honey) were the major sources of AS at all-time points and contributed to more than 40% and 35% of AS intake in men and women, respectively. Intake of sugar products decreased in men during follow-up (Ptrend < 0.001). An overall downward trend was observed in AS intake in both genders, however, was only significant for men during 15 years of follow-up. Table sugar and sugar-containing spreads represent the major source of AS in this cohort of older Australians. © 2016 The British Dietetic Association Ltd.

  17. Genetic association of refractive error and axial length with 15q14 but not 15q25 in the Blue Mountains Eye Study cohort.

    PubMed

    Schache, Maria; Richardson, Andrea J; Mitchell, Paul; Wang, Jie Jin; Rochtchina, Elena; Viswanathan, Ananth C; Wong, Tien Y; Saw, Seang Mei; Topouzis, Fotis; Xie, Jing; Sim, Xueling; Holliday, Elizabeth G; Attia, John; Scott, Rodney J; Baird, Paul N

    2013-02-01

    Myopia is a common complex condition influenced by genetic and environmental factors. Two recent genome-wide association studies have identified loci on chromosomes 15q25 and 15q14 associated with refractive error in Caucasian populations. Our study aimed to assess the association of these 2 loci with refractive error and ocular biometric measures in an independent ethnically matched Caucasian cohort. Genetic association study using unrelated individuals. Blue Mountains Eye Study (BMES) cohort. A total of 1571 individuals were included in this study. Single nucleotide polymorphism (SNP) genotype data were collected from the BMES cohort as part of the Wellcome Trust Case Control Consortium 2. Imputation was performed using MACH version 1.1.16, and statistical analysis was conducted using PLINK. Association tests were performed at both loci using refractive error (spherical equivalent), axial length, corneal curvature, and anterior chamber depth as the phenotypes. Refractive error, axial length, corneal curvature, and anterior chamber depth. A total of 1571 individuals were available from the BMES for analysis. A statistically significant association for refractive error was evident for SNPs at the 15q14 locus, with P values ranging from 1.5 × 10(-2) at rs685352 to 6.4 × 10(-4) at rs560764, whereas association could not be confirmed for SNPs at the 15q25 locus, with P values ranging from 8.0 × 10(-1) to 6.4 × 10(-1). Ocular biometric analysis revealed that axial length was the most likely trait underlying the refractive error association at the 15q14 locus for SNPs rs560766 (P=0.0054), rs634990 (P=0.0086), and rs8032019 (P=0.0081). Our results confirm the association with refractive error at the 15q14 locus but do not support the association observed at the 15q25 locus. Axial length seemed to be a major parameter at the 15q14 locus, underscoring the importance of this locus in myopia and future clinical treatment. Copyright © 2013 American Academy of

  18. [Blue light and eye health].

    PubMed

    Zou, Leilei; Dai, Jinhui

    2015-01-01

    Blue light, with the wavelength between 400 nm and 500 nm, has caused public concern because of the injury to the retinal cells. Meanwhile, it is important in circadian rhythm regulation, scotopic vision and ocular growth. Is the blue light safe? Should it be eliminated from the daily life? Here we review the effect and safety of the blue light.

  19. Aspen biology, community classification, and management in the Blue Mountains

    Treesearch

    David K. Swanson; Craig L. Schmitt; Diane M. Shirley; Vicky Erickson; Kenneth J. Schuetz; Michael L. Tatum; David C. Powell

    2010-01-01

    Quaking aspen (Populus tremuloides Michx.) is a valuable species that is declining in the Blue Mountains of northeastern Oregon. This publication is a compilation of over 20 years of aspen management experience by USDA Forest Service workers in the Blue Mountains. It includes a summary of aspen biology and occurrence in the Blue Mountains, and a...

  20. Eye damage control by reduced blue illumination.

    PubMed

    Ueda, Toshihiko; Nakanishi-Ueda, Takako; Yasuhara, Hajime; Koide, Ryohei; Dawson, William W

    2009-12-01

    The aim of this study was to demonstrate that a blue light and ultraviolet cut-off filter (blue filter) could reduce short-wavelength retina/RPE damage threshold by a continuous spectrum source. Sixteen normal eyes of two rhesus monkeys and six cynomolgus monkeys were subjected to macular irradiation of 20, 24, 27.4, 30, 35, 45, 50 and 60 J/cm(2) energy densities. The values of energy density were measured before the blue filter. Lesions were measured before and at 2 and 30 days after irradiation of a 2.8 mm diameter region within the macular arcade. Measures were fundoscopy, fluorescein angiography and long wavelength scanning by the Heidelberg Retinal Tomograph (HRT) unit. The lesions, which were produced, were scored and compared to irradiant energy density of the blue LED (NSPB500S, Nichia, Tokushima, Japan). The exposure at the 20 J/cm(2) produced no detectable result at 2 or 30 days. Exposure at 35 J/cm(2) showed definite lesion production without blue filter. With the filter added there was one indication of minor change. At 60 J/cm(2) there was extensive heavy, enduring damage without the filter and with the filter damage was present but was significantly attenuated. These results strongly support the conclusion that the blue filter attenuation reduces the frequency of damage by exposure. This experimental system is a useful model for normal human eye aging and continuous spectrum environment irradiance.

  1. Sustaining the land, people, and economy of the Blue Mountains: The Blue Mountains Natural Resources Institute

    Treesearch

    Lynn Starr; James McIver; Thomas M. Quigley

    2000-01-01

    The Blue Mountains Natural Resources Institute approaches issues by deciding if a critical issue is one of information needs or of differing values. If a values issue, we arrange local forums for discussion; if an information issue, we disseminate available information, or undertake research projects as appropriate. One issue we have researched involving both values...

  2. Climate change vulnerability and adaptation in the Blue Mountains

    Treesearch

    Jessica E. Halofsky; David L. Peterson

    2017-01-01

    The Blue Mountains Adaptation Partnership was developed to identify climate change issues relevant to resource management in the Blue Mountains region, to find solutions that can minimize negative effects of climate change, and to facilitate transition of diverse ecosystems to a warmer climate. Partnering organizations included three national forests (Malheur, Umatilla...

  3. The University of Montana's Blue Mountain Observatory

    NASA Astrophysics Data System (ADS)

    Friend, D. B.

    2004-12-01

    The University of Montana's Department of Physics and Astronomy runs the state of Montana's only professional astronomical observatory. The Observatory, located on nearby Blue Mountain, houses a 16 inch Boller and Chivens Cassegrain reflector (purchased in 1970), in an Ash dome. The Observatory sits just below the summit ridge, at an elevation of approximately 6300 feet. Our instrumentation includes an Op-Tec SSP-5A photoelectric photometer and an SBIG ST-9E CCD camera. We have the only undergraduate astronomy major in the state (technically a physics major with an astronomy option), so our Observatory is an important component of our students' education. Students have recently carried out observing projects on the photometry of variable stars and color photometry of open clusters and OB associations. In my poster I will show some of the data collected by students in their observing projects. The Observatory is also used for public open houses during the summer months, and these have become very popular: at times we have had 300 visitors in a single night.

  4. The blue-eyes stereotype: do eye color, pupil diameter, and scleral color affect attractiveness?

    PubMed

    Gründl, Martin; Knoll, Sebastian; Eisenmann-Klein, Marita; Prantl, Lukas

    2012-04-01

    Blue eyes have been the embodiment of attractiveness not only for decades but even for centuries. The primary aim of this study was to determine whether iridal color, particularly color blue, can increase the attractiveness of a person's eye area. As a secondary aim, the study examined the impact of pupil diameter and scleral color on the attractiveness of the eye area. The stimulus material comprised images of the eye areas of 60 women ages 15-65 years. A total of 80 participants rated the attractiveness of each eye area on a 7-point Likert scale and estimated the age of the person. The color values of the iris and sclera were measured. As an additional subsample, 50% of the participants were asked what features of each eye area they found particularly appealing. Most surprisingly, no correlation was found between iridal color and rated attractiveness. However, the participants mentioned the color blue more often as a positive aspect than other iridal colors. A high inverse correlation was observed between attractiveness of the eye area and age. The larger the pupil diameter and the whiter the scleral color, the lower was the real and perceived age and the higher was the attractiveness. The data showed that the "blue-eyes stereotype" does exist. People consider blue eyes attractive, but in reality, blue is rated as attractive as other iridal colors. Bright scleral color and large pupils positively affect attractiveness because both features are significantly correlated with youthfulness.

  5. Blue eyes as a risk factor for type 1 diabetes.

    PubMed

    Di Stasio, Enrico; Maggi, Daria; Berardesca, Enzo; Marulli, Georgiana Clare; Bizzarri, Carla; Lauria, Angelo; Portuesi, Rosalba; Cavallo, Maria Gisella; Costantino, Francesco; Buzzetti, Raffaella; Astorri, Elisa; Pitocco, Dario; Songini, Marco; Pozzilli, Paolo

    2011-09-01

    A high frequency of blue eyes and fair skin are reported in northern European Caucasians with type 1 diabetes (T1D). Also there is an inverse relationship between latitude and T1D incidence. We determined whether iris colour and skin pigmentation are risk factors in a Caucasian population living in two Mediterranean regions located at the same latitude with higher ultraviolet B irradiance, but with different T1D incidence. We studied iris colour in 281 consecutive subjects with T1D and 298 controls. Skin type was evaluated by melanin quantification. In Lazio, blue eyes and fair skin type are significantly more common in T1D subjects than in controls (21 versus 9%, p = 0.002; 50 versus 35%, p < 0.001, respectively). In Sardinia, the frequency of blue eyes in T1D subjects is twice that in controls (5.8 versus 2.6% and significantly higher when compared to the expected calculated frequency in the entire population). By logistic regression analysis, only blue eyes are independent and significant predictors of T1D [odds ratio for blue eyes = 2.2; 95% confidence interval (1.1-4.4), p = 0.019]. As previously shown in a Caucasian population from northern Europe, blue eyes and a trend for fair skin increase the risk for T1D also in a Caucasian population born and residing in a Mediterranean region (Continental Italy). This finding may be relevant for explaining different T1D incidence as prevalence of blue eyes differ substantially between northern and southern European Caucasians. Copyright © 2011 John Wiley & Sons, Ltd.

  6. 77 FR 45715 - Notice of Public Hearing: Reading Blue Mountain and Northern Railroad

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... FRA-2003-15754] Notice of Public Hearing: Reading Blue Mountain and Northern Railroad The Reading Blue Mountain and Northern Railroad (RBMN) has petitioned the Federal Railroad Administration (FRA) seeking the...

  7. The timber resources of the Blue Mountain area, Oregon.

    Treesearch

    Charles L. Bolsinger; John M. Berger

    1975-01-01

    The latest inventory of the timber resources of the Blue Mountain Area of Oregon indicates that there are about 47 billion board feet of sawtimber on 4.6 million acres of commercial forest land. Public agencies administer about 76 percent of the area and hold 89 percent of the sawtimber volume; farmer and miscellaneous private ownerships account for 16 percent of the...

  8. Lodgepole pine in the Blue Mountains of northeastern Oregon.

    Treesearch

    James M. Trappe; Robert W. Harris

    1958-01-01

    Lodgepole pine (Pinus contorta) is a major species in northeastern Oregon. The lodgepole type covers nearly 400,000 acres in the Blue and Wallowa Mountains, and individual trees are scattered over many of the remaining six million forested acres in this area (2). The type blankets large areas in watersheds in a region where spring floods and summer...

  9. Aspen restoration in the Blue Mountains of northeast Oregon

    Treesearch

    Diane M. Shirley; Vicky Erickson

    2001-01-01

    In the Blue Mountains of northeast Oregon, quaking aspen is on the western fringe of its range. It exists as small, scattered, remnant stands of rapidly declining trees. Although little is known about the historic distribution of aspen in Oregon, it is believed that stands were once larger and more widely distributed. Decline of the species is attributed to fire...

  10. Forest health in the Blue Mountains: social and economic perspectives.

    Treesearch

    T.M. Quigley

    1992-01-01

    The Blue Mountains of northeast Oregon and southeast Washington are among the most insect- and disease-infested forests of North America. The communities, industries, rural residents, and economies that are highly dependent on the flow of natural resources are being stressed as uncertainty increases over future resource availability. This paper examines, from social...

  11. Wild edible mushrooms in the Blue Mountains: resource and issues.

    Treesearch

    Catherine G. Parks; Craig L. Schmitt

    1997-01-01

    This paper reviews the wild mushroom resource of the Blue Mountains of northeastern Oregon and southeastern Washington and summarizes issues and concerns for regulation, monitoring, and management. Existing biological information on the major available commercial mushrooms in the area, with emphasis on morels, is presented. Brief descriptions of the most commonly...

  12. Sharing the Arts of the Blue Ridge Mountains. Candles.

    ERIC Educational Resources Information Center

    Holman, Martha; Gailey, Lamar

    This module on candles is one of eight modules designed to provide instruction on authentic Blue Ridge Mountain crafts to adult basic education students at a low cost. Contents include notes on the history of candle making; process used, including equipment and materials, as well as method described narratively and graphically; and the followup,…

  13. For Internet Knowledge, Should You Ask Ol' Blue Eyes or the Brown-Eyed Girl?

    ERIC Educational Resources Information Center

    Boshier, Roger; Kolpakova, Yulia; Klinkhamer, Sooz

    2004-01-01

    The digital divide is generally thought to arise from socio-economic disparities. However, there is more to it. Eye colour is a factor. In this study, the 16 multiple-choice item Internet Quiz was administered to 3,208 respondents in the Lower Mainland (Vancouver) of British Columbia, Canada. Blue and hazel-eyed people knew significantly more…

  14. For Internet Knowledge, Should You Ask Ol' Blue Eyes or the Brown-Eyed Girl?

    ERIC Educational Resources Information Center

    Boshier, Roger; Kolpakova, Yulia; Klinkhamer, Sooz

    2004-01-01

    The digital divide is generally thought to arise from socio-economic disparities. However, there is more to it. Eye colour is a factor. In this study, the 16 multiple-choice item Internet Quiz was administered to 3,208 respondents in the Lower Mainland (Vancouver) of British Columbia, Canada. Blue and hazel-eyed people knew significantly more…

  15. Blue Mountain, Humboldt County, Nevada, U.S.A

    SciTech Connect

    Ted Fitzpatrick, Brian D. Fairbank

    2005-04-01

    The report documents the drilling of well Deep Blue No.2, the second deep geothermal test hole at the Blue Mountain Geothermal Area, Humboldt County, Nevada. The well was drilled by Noramex Corp, a Nevada company, with funding support from the US Department of Energy, under the DOE’s GRED II Program. Deep Blue No.2 was drilled as a ‘step-out’ hole from Deep Blue No.1, to further evaluate the commercial potential of the geothermal resource. Deep Blue No.2 was designed as a vertical, slim observation test hole to a nominal target depth of 1000 meters (nominal 3400 feet). The well tests an area of projected high temperatures at depth, from temperature gradients measured in a group of shallow drill holes located approximately one kilometer to the northeast of observation hole Deep Blue No.1. The well is not intended for, or designed as, a commercial well or a production well. Deep Blue No.2 was spudded on March 25, 2004 and completed to a total depth of 1127.76m (3700 ft) on April 28, 2004. The well was drilled using conventional rotary drilling techniques to a depth of 201.17 m (660 ft), and continuously cored from 201.17m (660 ft) to 1127.76m (3700 ft). A brief rig-on flow-test was conducted at completion to determine basic reservoir parameters and obtain fluid samples. A permeable fracture zone with measured temperatures of 150 to 167°C (302 to 333°F) occurs between 500 to 750m (1640 to 2461ft). The well was left un-lined in anticipation of the Phase III - Flow and Injection Testing. A further Kuster temperature survey was attempted after the well had been shut in for almost 3 weeks. The well appears to have bridged off at 439m (1440ft) as the Kuster tool was unable to descend past this point. Several attempts to dislodge the obstruction using tube jars were unsuccessful. Deep Blue No.2 encountered variably fractured and veined, fine-grained rocks of the Singas Formation, and intruded by minor strongly altered fine-grained felsic dikes, and less altered

  16. 'Behind blue eyes'†: the association between eye colour and deep infiltrating endometriosis.

    PubMed

    Vercellini, Paolo; Buggio, Laura; Somigliana, Edgardo; Dridi, Dhouha; Marchese, Maria Antonietta; Viganò, Paola

    2014-10-10

    Is the prevalence of blue eye colour higher in women with deep endometriosis? Blue eye colour is more common in women with deep endometriosis when compared with both women with ovarian endometriomas and women without a history of endometriosis. Recent and intriguing evidence suggests that women with deep endometriosis may have particular phenotypic characteristics including a higher prevalence of a light-colour iris. Available epidemiological evidence is however weak. Case-control study performed in a large academic department specializing in the study and treatment of endometriosis. Individual iris colour was evaluated in daylight and categorized in three grades, namely blue-grey (blue), hazel-green (green) and brown. One observer assessed iris colour. In addition, the women themselves were invited to indicate the colour of their eyes according to the same classification system. Cases with discordant eye colour determinations between the observer and the woman were excluded from the final analysis. Two hundred and twenty-three women with deep endometriosis (cases), 247 with ovarian endometriomas and 301 without a history of endometriosis were enrolled. After exclusion of 52 discordant cases, the proportions of brown, blue and green eye colours were, respectively, 61, 30 and 9% in the deep endometriosis group, 74, 16 and 10% in the endometrioma group and 75, 15 and 10% in the non-endometriosis group. Women in the deep endometriosis group had a statistically significant excess of blue eyes and a reduced proportion of brown eyes compared with the two control groups (P = 0.002 and P < 0.001, respectively). The proportion of blue eyes was almost identical in the ovarian endometrioma group and the non-endometriosis group, and that of green eyes was substantially similar in all study groups. The OR (95% CI) of having blue eyes in women with deep endometriosis compared with women with ovarian endometriosis and with those without endometriosis was, respectively, 2.2 (1

  17. Climate change, fish, and aquatic habitat in the Blue Mountains [Chapter 5

    Treesearch

    Daniel J. Isaak; Katherine Ramsey; John C. Chatel; Deborah L. Konnoff; Robert A. Gecy; Dona Horan

    2017-01-01

    National Forest System lands in the Blue Mountains region support a diversity of important native aquatic species that will be affected by climate change. As part of the Blue Mountains Adaptation Partnership, four of these species (spring Chinook salmon (Oncorhynchus tshawytscha Walbaum in Artedi), bull trout (Salvelinus confluentus Suckley), summer steelhead (O....

  18. Strategies and recommendations for addressing forest health issues in the Blue Mountains of Oregon and Washington.

    Treesearch

    J.A. Tanaka; G.L. Starr; T.M. Quigley

    1995-01-01

    The Blue Mountains Natural Resources Institute held three types of meetings to obtain public and scientific input into the development of strategies and recommendations for addressing forest health issues in the Blue Mountains of Oregon and Washington. Seven strategies are proposed: (1) plan and implement management activities on a landscape level; (2) enhance training...

  19. Effects of Climatic Variability and Change on Upland Vegetation in the Blue Mountains [Chapter 6].

    Treesearch

    Becky K. Kerns; David C. Powell; Sabine Mellmann-Brown; Gunnar Carnwath; John Kim

    2017-01-01

    The Blue Mountains ecoregion (BME) extends from the Ochoco Mountains in central Oregon to Hells Canyon of the Snake River in extreme northeastern Oregon and adjacent Idaho, and then north to the deeply carved canyons and basalt rimrock of southeastern Washington (see fig. 1.1 in chapter 1). The BME consists of a series of mountain ranges occurring in a southwest to...

  20. Heating facilities, Blue Mountain Community College, Pendleton, Oregon

    SciTech Connect

    Not Available

    1980-12-30

    Blue Mountain Community College campus consists of five major buildings totalling about 193,000 square feet in area. Four of these buildings are heated using hot water circulating systems, and the fifth by a low pressure steam system. The boilers for each of the systems are natural gas fired. A successful agricultural well was drilled adjacent to the campus, which during a twelve hour test produced 780 gallons per minute of 65/sup 0/F water. It was concluded that heating the campus utilizing a heat pump system is possible using readily available and proven equipment. Annual energy saving in natural gas will amount to 98,400 therms. This is an 82% reduction in the annual usage forecast after implementation of recommendations made as a result of the energy audit. The first year value of the natural gas saved is $49,200. This savings, less operating costs, when applied with escalation consideration over a period of twenty years, indicates that a capital investment of $367,500 can be justified. This assumes the project would be financed with 8% tax-free bonds. A system design was developed, new equipment sized, needed modifications identified, and major items estimated.

  1. Seismic Characterization of the Blue Mountain Geothermal Site

    NASA Astrophysics Data System (ADS)

    Templeton, D. C.; Matzel, E.; Cladouhos, T. T.

    2016-12-01

    In geothermal areas, seismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection (e.g. STA/LTA) and location techniques are often employed to identify microearthquakes. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Advanced earthquake detection techniques can be applied in these regions to identify these missed events. For this application, known larger events are used as templates to identify nearby smaller events. Here we investigate the seismic activity within the Blue Mountain Geothermal Power Plant located in Humboldt County, Nevada between December 2015 to May 2016. We compare the effectiveness of direct spatial-temporal cross-correlation templates with Matched Field Processing (MFP) derived templates and compare these results with earthquake detection results from a traditional STA/LTA algorithm. Preliminary results show significant clustering of microearthquakes, most probably influenced by plant operations. The significant increase in data availability that advanced earthquake detection methods can provide improves the statistical analyses of induced seismicity sequences, reveal critical information about the ongoing evolution of the subsurface reservoir, and better informs the construction of models for hazard assessments. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  2. Guide to the common Potentilla species of the Blue Mountains ecoregion.

    Treesearch

    Marti Aitken; Catherine Gray. Parks

    2004-01-01

    This guide will assist field identification of Potentilla species likely to be found in the Blue Mountains region. Many species formerly classified in the genus Potentilla are also included. Illustrations accompany the descriptions and glossary.

  3. Effects of timber harvest on elk distribution in the Blue Mountains of Oregon.

    Treesearch

    Jon M. Skovlin; Larry D. Bryant; Paul J. Edgerton

    1989-01-01

    A long-term study to determine the effects of several methods of timber harvest on the distribution of Rocky Mountain elk (Cervus elaphus nelsoni) was begun in the early 1970's in the Blue Mountains of northeastern Oregon. The study area was an upper slope spruce-fir type with harvest designed to compare changes in elk use, as measured by...

  4. Application of LANDSAT MSS to elk habitat management. [Blue Mountains, Oregon

    NASA Technical Reports Server (NTRS)

    Schrumpf, B. J.

    1981-01-01

    The utilization of information derived from LANDSAT multispectral scanner data to estimate the impact of proposed timber harvests on potential elk use is briefly discussed. The evaluations were conducted in Northeastern Oregon where several herds of Rocky Mountain elk range in the Blue Mountains. The inventory product is a geographically referenced data base containing land cover types and habitat components (cover/forage).

  5. Holocene erosion, sedimentation, and stratigraphy at Raven Fork, Southern Blue Ridge Mountains, USA

    Treesearch

    David S. Leigh; Paul A. Webb

    2006-01-01

    Holocene colluvial and alluvial stratigraphy and a radiocarbon chronology are presented for the valley of the lower three kilometers of Raven Fork, a mountain stream draining 194 km2 of high relief (1.3 km) terrain of the Southern Blue Ridge Mountains in western North Carolina, USA, which is in a region that lacks good chronological data. Lower hillslopes, alluvial/...

  6. Mapping genetic variation and seed zones for Bromus carinatus in the Blue Mountains of eastern Oregon, USA

    Treesearch

    R.C. Johnson; Vicky J. Erickson; Nancy L. Mandel; J. Bradley St. Clair; Kenneth W. Vance-Borland

    2010-01-01

    Seed transfer zones ensure that germplasm selected for restoration is suitable and sustainable in diverse environments. In this study, seed zones were developed for mountain brome (Bromus carinatus Hook. & Arn.) in the Blue Mountains of northeastern Oregon and adjoining Washington. Plants from 148 Blue Mountain seed source locations were...

  7. Geology of the Blue Mountains region of Oregon, Idaho, and Washington: Petrology and tectonic evolution of pre-tertiary rocks of the Blue Mountains region. Professional paper

    SciTech Connect

    Vallier, T.L.; Brooks, H.C.

    1995-12-31

    U.S. Geological Survey Professional Paper 1438 is one volume of a five-volume series on the geology, paleontology, and mineral resources of the Blue Mountains region eastern Oregon, western Idaho, and southeastern Washington. This professional paper deals specifically with petrology and tectonic evolution.

  8. Blue eyes in lemurs and humans: same phenotype, different genetic mechanism.

    PubMed

    Bradley, Brenda J; Pedersen, Anja; Mundy, Nicholas I

    2009-06-01

    Almost all mammals have brown or darkly-pigmented eyes (irises), but among primates, there are some prominent blue-eyed exceptions. The blue eyes of some humans and lemurs are a striking example of convergent evolution of a rare phenotype on distant branches of the primate tree. Recent work on humans indicates that blue eye color is associated with, and likely caused by, a single nucleotide polymorphism (rs12913832) in an intron of the gene HERC2, which likely regulates expression of the neighboring pigmentation gene OCA2. This raises the immediate question of whether blue eyes in lemurs might have a similar genetic basis. We addressed this by sequencing the homologous genetic region in the blue-eyed black lemur (Eulemur macaco flavifrons; N = 4) and the closely-related black lemur (Eulemur macaco macaco; N = 4), which has brown eyes. We then compared a 166-bp segment corresponding to and flanking the human eye-color-associated region in these lemurs, as well as other primates (human, chimpanzee, orangutan, macaque, ring-tailed lemur, mouse lemur). Aligned sequences indicated that this region is strongly conserved in both Eulemur macaco subspecies as well as the other primates (except blue-eyed humans). Therefore, it is unlikely that this regulatory segment plays a major role in eye color differences among lemurs as it does in humans. Although convergent phenotypes can sometimes come about via the same or similar genetic changes occurring independently, this does not seem to be the case here, as we have shown that the genetic basis of blue eyes in lemurs differs from that of humans.

  9. Water fluoridation in the Blue Mountains reduces risk of tooth decay.

    PubMed

    Evans, R W; Hsiau, A C Y; Dennison, P J; Patterson, A; Jalaludin, B

    2009-12-01

    In April 1992, the fluoride concentration in the Blue Mountains water supply was adjusted to 1 mg/L. Baseline dmft/DMFT has been determined in children attending schools in the region and in the adjacent reference region of Hawkesbury, fluoridated since 1968. The aim of this study was to evaluate the effect of the water fluoridation programme in the Blue Mountains. In 2003, children attending the same schools were sampled. Residential history data were obtained by questionnaire and caries experience was assessed according to WHO guidelines. The analysis was restricted to lifelong resident children aged 5-11 years. The baseline and follow-up dmft scores for Blue Mountains children aged 5-8 years were 2.36 and 0.67, respectively. The age-adjusted decrease in odds of experiencing one or more dmft due to fluoridation was 0.26 (CI(95) 0.19, 0.37). The corresponding DMFT scores for Blue Mountains children aged 8-11 were 0.76 and 0.21 and the corresponding decrease in odds of experiencing one or more DMFT due to fluoridation was 0.25 (CI(95) 0.16, 0.40). Tooth decay reduction observed in the Blue Mountains corresponds to high rates reported elsewhere and demonstrates the substantial benefits of water fluoridation.

  10. [Discovery and genetic analysis of blue-eyed mutant in the white rex rabbits].

    PubMed

    Pang, You-Zhi; Xu, Yong-Fei

    2013-06-01

    Using cross, backcross, and full-sib mating experiments, allelism test was conducted to study the genetic mechanism of blue-eyed mutant of the white rex rabbits originated from the F1 generation from the cross American White rex rabbits(♂) × Chinchilla meat rabbits(♀). The study showed that the reason for the blue-eyed mutant of the white rex rabbits was a recessive mutation in Vienna locus. When the V locus was homozygous for the recessive v gene, it was recessive epistatic to other loci (including A, B, C, D, and E), which also controlled the coat color. Regardless of the genotypes in other gene loci, the rabbits appeared blue eyes and white coat color as long as the genotype vv occurred at the Vienna locus. Thus, the combination of genotype vv and genotype rr will produce the blue-eyed and the white rex rabbits. As the blue-eyed mutant of the white rex rabbits is a new finding in China's rabbit breeding program, it is significant to explain the genetic mechanism of the blue-eyed mutant for the breeding and production of rex rabbits.

  11. Breeding for better eye health in Finnish blue fox (Vulpes lagopus).

    PubMed

    Kempe, R; Strandén, I

    2016-02-01

    The frequency of eye infections in the Finnish blue fox population has increased during the past decade. Eye infection may incur economic losses to producers due to reduced selection intensity, but ethical aspects need to be considered as well because eye infection can be quite painful and reduce animal well-being. The purpose of this study was to determine the potential for genetic selection against susceptibility to eye infection. The data were collected from 2076 blue foxes at the MTT fur animal research station. Genetic parameters were estimated using single- and multiple-trait animal models. The heritability estimate for eye infection was analysed as a binary trait (EYE) and was moderate (0.24 ± 0.07). EYE had a moderate antagonistic genetic correlation (-0.49 ± 0.20) with grading density (thick underfur). The genetic correlation of EYE with grading size or body condition score was estimated without precision, but all size traits had a low antagonistic phenotypic correlation with EYE. Our results suggest that there is genetic variance in susceptibility to EYE, indicating that eye health can be improved through selection. The current recommendation is that the sick animals should be culled immediately. If more efficient selection is needed, the selection index and multiple-trait animal models can be applied in breeding for better eye health.

  12. Geology of the Blue Mountains region of Oregon, Idaho, and Washington; petrology and tectonic evolution of pre-Tertiary rocks of the Blue Mountains region

    USGS Publications Warehouse

    Vallier, T. L.; Brooks, H.C.

    1995-01-01

    This Professional Paper contains 14 chapters on the Blue Mountains region of Oregon, Idaho, and Washington. The authors discuss petrology and tectonic evolution of an island arc that formed in the ancestral Pacific Ocean during the Permian to Cretaceous interval. The island arc was accreted to cratonal North America in the Early Cretaceous and thereby became one of the several exotic terranes in western North America.

  13. Combatant eye protection: an introduction to the blue light hazard

    NASA Astrophysics Data System (ADS)

    Lattimore, Morris R.

    2016-05-01

    Emerging evidence of metabolic vulnerability to visible blue light is vitally important, as it is indicative of a scalable threshold effect. Added stressors (e.g., increased altitude or contact lens wear) could shift the wavelength effects toward a more damaging clinical picture. Recent reports have indicated rod photo-pigment damage resulting from solar blue-light exposures, adversely affecting unaided night vision, a militarily important performance decrement. The activation wavelength for the daily synchronous setting of the Circadian Clock, which regulates the synchronization of all hormonal and organ systems throughout the body, falls within this blue light perceptual range.

  14. Effects of long-term use by big game and livestock in the Blue Mountains forest ecosystems.

    Treesearch

    Larry L. Irwin; John G. Cook; Robert A. Riggs; Jon M. Skovlin

    1994-01-01

    The effects on eastside forest ecosystems from long-term grazing by large mammals are assessed, because long-term herbivory can reduce or increase ecosystem productivity. The assessment emphasizes elk and cattle in the Blue Mountains of northeast Oregon and southeast Washington. Histories of populations of large mammals and their effects in the Blue Mountains are...

  15. Climate change and hydrology in the Blue Mountains [Chapter 3

    Treesearch

    Caty F. Clifton; Kate T. Day; Kathie Dello; Gordon E. Grant; Jessica E. Halofsky; Daniel J. Isaak; Charles H. Luce; Mohammad Safeeq; Brian P. Staab; John Stevenson

    2017-01-01

    The dominant influences on climatic patterns in the Pacific Northwest are the Pacific Ocean and the Cascade Range. The diurnal temperature range is higher east of the Cascade crest, further inland from the Pacific Ocean. More precipitation falls west of the Cascade Mountains crest, and a strong rain shadow greatly reduces precipitation east of the crest. The southern...

  16. The Blue Mountains Natural Resources Institute: partnerships that demonstrate the role of silviculture in forest management

    Treesearch

    James McIver; Andrew Youngblood

    1997-01-01

    The research program of the Blue Mountains Natural Resources Institute (BMNRI) aims to understand the ecological effects of current management practices. In forest systems, this amounts to silvicultural research. We describe how the BMNRl fosters partnerships to carry out and showcase silvicultural research leading to information that allows assessment of economic/...

  17. Habitat-effectiveness index for elk on Blue Mountain Winter Ranges.

    Treesearch

    Jack Ward Thomas; Donavin A. Leckenby; Mark Henjum; Richard J. Pedersen; Larry D. Bryant

    1988-01-01

    An elk-habitat evaluation procedure for winter ranges in the Blue Mountains of eastern Oregon and Washington is described. The index is based on an interaction of size and spacing of cover and forage areas, roads open to traffic per unit of area, cover quality, and quantity and quality of forage.

  18. Disturbance and canopy gaps as indicators of forest health in the Blue Mountains of Oregon.

    Treesearch

    Jerome S. Beatty; Brian W. Geils; John E. Lundquist

    1995-01-01

    Disturbance profiles, indices based on both spatial and non-spatial statistics, are used to examine how small-scale disturbances and the resulting canopy gaps disrupt ecosystem patterns and processes in selected stands in the Blue Mountains of Oregon. The biological meaning of many indices remains undefined for small scale disturbance phenomena, but their disturbance...

  19. Forest health in the Blue Mountains: an plant ecologist's perspective on ecosystem processes and biological diversity.

    Treesearch

    Charles G. Johnson

    1994-01-01

    Natural disturbances are important to ecosystem processes. Disturbances historically have occurred in the vegetation of the Blue Mountain area of northeastern Oregon and southeastern Washington. The primary modifying events that historically have cycled through most of its plant communities are fire, grazing and browsing, insect and disease epidemics, windthrow,...

  20. Morphological and sedimentological responses of streams to human impact in the southern Blue Ridge Mountains, USA

    Treesearch

    Katie Price; David S. Leigh

    2006-01-01

    Morphological and sedimentological responses of streams to basin-scale impact have been well documented for intensively agricultural or urban areas. Sensitivity thresholds of streams to modest levels of disturbance, however, are not well understood. This study addresses the influence of forest conversion on streams of the southern Blue Ridge Mountains, a region that...

  1. Forest management in the Blue Mountains: public perspectives on prescribed fire and mechanical thinning

    Treesearch

    Bruce Shindler; Michelle. Reed

    1996-01-01

    Insect and disease epidemics have created unhealthy and overstocked conditions in national forests of the Blue Mountains. Two of the most important management tools for reducing fuel loads and restoring forest health are prescribed fire and mechanical thinning practices. Accurate information about public support for these practices is essential for implementing...

  2. Modeling stream-bank erosion in the Southern Blue Ridge Mountains

    Treesearch

    James C. Rogers; David S. Leigh

    2013-01-01

    Deforestation, followed by soil erosion and subsequent deposition of alluvium in valleys, played a critical role in the formation of historical terraces in much of the Southern Blue Ridge Mountains. Such terraces add a significant amount of sediment to the tributaries of the region as streams laterally erode the terrace banks. This study examined the contribution of...

  3. Forest health in the Blue Mountains: the influence of insects and disease.

    Treesearch

    B.E. Wickman

    1992-01-01

    A science perspective of forest health in the Blue Mountains is summarized by using both historical and biological information. Many of the current pest problems are related to human activities that have occurred over the last 90 years. The almost complete loss of periodic low-intensity fires since 1900 plus extensive logging of pine have resulted in many thousands of...

  4. Forest health in the Blue Mountains: a management strategy for fire-adapted ecosystems.

    Treesearch

    R.W. Mutch; S.F. Arno; J.K. Brown; C.E. Carlson; R.D. Ottmar; J.L. Peterson

    1993-01-01

    The fire-adapted forests of the Blue Mountains are suffering from a forest health problem of catastrophic proportions. Contributing to the decline of forest health are such factors as the extensive harvesting of the western larch and ponderosa pine overstory during the 1900s, attempted exclusion of fire from a fire-dependent ecosystem, and the continuing drought. The...

  5. Climate change, water resources, and roads in the Blue Mountains [Chapter 4

    Treesearch

    Caty F. Clifton; Kate T. Day; Gordon E. Grant; Jessica E. Halofsky; Charles H. Luce; Brian P. Staab

    2017-01-01

    Water is a critical resource in dry forest and rangeland environments of western North America, largely determining the distribution of plant and animal species across a broad range of elevations and ecosystems. Water is also essential for human endeavors, directly affecting where and how human communities and local economies have developed. The Blue Mountains of...

  6. Geology of the Blue Mountains region of Oregon, Idaho, and Washington

    SciTech Connect

    Walker, G.W. )

    1990-01-01

    This volume reports on the geology of the Blue Mountains region, consists of six chapters having various individual authorship. This book focuses on the stratigraphy, ages, structure, and chemical characteristics of terrestrial Cenozoic volcanic and volcaniclastic rocks of the region and on the relation of the Cenozoic volcanism to tectonism.

  7. Bacteria and Turbidity Survey for Blue Mountain Lake, Arkansas, Spring and Summer, 1994

    USGS Publications Warehouse

    Lasker, A. Dwight

    1995-01-01

    Introduction Blue Mountain Lake darn is located at river mile 74.4 on the Petit Jean River in Logan and Yell Counties in west-central Arkansas (fig. 1). Drainage area above the darn is 488 square miles. Blue Mountain Lake is located between two national forests-the Ozark National Forest and the Ouachita National Forest. The primary purpose for Blue Mountain Lake is flood control, but the lake is used for a variety of recreational purposes. The U.S. Geological Survey (USGS) in cooperation with the U.s. Army Corps of Engineers, Little Rock District, conducted a bacterial and turbidity study of the Blue Mountain Lake Basin during the spring and suri1mer 1994. Samples were collected weekly at 11 locations within the lake basin from May through September 1994. Eight sampling sites were located on tributaries to the lake and three sampling sites were located on the lake with one of the sites located at a swim beach (fig. 2; table 1).

  8. Assessment of timber availability from forest restoration within the Blue Mountains of Oregon.

    Treesearch

    Robert Rainville; Rachel White; Jamie Barbour

    2008-01-01

    Changes in forest management have detrimentally affected the economic health of small communities in the Blue Mountain region of Oregon over the past few decades. A build-up of small trees threatens the ecological health of these forests and increases wildland fire hazard. Hoping to boost their economies and also restore these forests, local leaders are interested in...

  9. Predicting Microstegium vimineum invasion in natural plant communities of the southern Blue Ridge Mountains, USA

    Treesearch

    Dean P. Anderson; Monica G. Turner; Scott M. Pearson; Thomas P. Albright; Robert K. Peet; Ann Wieben

    2012-01-01

    Shade-tolerant non-native invasive plant species may make deep incursions into natural plant communities, but detecting such species is challenging because occurrences are often sparse. We developed Bayesian models of the distribution of Microstegium vimineum in natural plant communities of the southern Blue Ridge Mountains, USA to address three objectives: (1) to...

  10. Interpreting long-term trends in Blue Mountain ecosystems from repeat photography.

    Treesearch

    Jon M. Skovlin; Jack Ward. Thomas

    1995-01-01

    Photographs taken before 1925 were compared with photos taken as recently as 1992 to interpret changes within ecosystems in the Blue Mountains of Oregon. For discussion purposes, 10 ecosystems were aggregated into seven broad landscape systems. Nearly all systems exhibited some degree of conversion from herbaceous to woody forms of vegetation. Nonforested ecosystems...

  11. Blue Mountains Ecoregion: Chapter 16 in Status and trends of land change in the Western United States--1973 to 2000

    USGS Publications Warehouse

    Soulard, Christopher E.

    2012-01-01

    The Blue Mountains Ecoregion encompasses approximately 65,461 km² (25,275 mi²) of land bordered on the north by the Columbia Plateau Ecoregion, on the east by the Northern Rockies Ecoregion, on the south by the Snake River Basin and the Northern Basin and Range Ecoregions, and on the west by the Cascades and the Eastern Cascades Slopes and Foothills Ecoregions (fig. 1) (Omernik, 1987; U.S. Environmental Protection Agency, 1997). Most of the Blue Mountains Ecoregion is located within Oregon (83.5 percent); 13.8 percent is in Idaho, and 2.7 percent is in Washington. The Blue Mountains are composed of primarily Paleozoic volcanic rocks, with minor sedimentary, metamorphic, and granitic rocks. Lower mountains and numerous basin-and-range areas, as well as the lack of Quaternary-age volcanoes, distinguish the Blue Mountains from the adjacent Cascade Range (Thorson and others, 2003).

  12. MISR Stereo Imagery of Blue Mountain Fires in New South Wales, Australia

    Atmospheric Science Data Center

    2013-12-17

    ... mild winter and an extremely hot September in Australia have led to an early start to the fire season Down Under. A number of significant ... can be viewed with standard red/blue 3D glasses with the red lens over the left eye. Sydney itself is in the bottom center of the image, ...

  13. Combatant Eye Protection: An Introduction to the Blue Light Hazard

    DTIC Science & Technology

    2015-12-01

    protection from penetrating ocular injury for over five years; the primary obstacle to the protective spectacle’s successful performance had been...100 percent. The risk of functional eye injury resulting from solar-based ultraviolet radiation (UVR) was less obvious, but clearly annotated over 30...the terminal discs while reforming the membrane over the tip of the cell. Next, the shed discs are surrounded by cytoplasmic extensions from the RPE

  14. Anterior uveal spindle cell tumor in a blue-eyed mixed-breed dog.

    PubMed

    Olbertz, Letícia; Langohr, Ingeborg; Werner, Juliana; Pessoa, Lenita; Kiupel, Matti; Agnew, Dalen; Montiani-Ferreira, Fabiano

    2013-07-01

    A female, eight-year-old, mixed-breed blue-eyed dog was presented for ophthalmic evaluation because its left eye had "changed color" one year previously. The before left eye was enucleated and submitted for evaluation. Histopathological analysis revealed an invasive neoplastic mass effacing most of the ventral aspect of the iris stroma. A diagnosis of an anterior uveal spindle cell tumor was made. Immunohistochemical results were strongly suggestive of a schwannoma, but some smooth muscle differentiation was also observed. Two and a half years after therapeutic enucleation there was no evidence of neoplasm recurrence or metastasis.

  15. Teaching the Blue-Eyed Islanders Puzzle in a Liberal Arts Mathematics Course

    ERIC Educational Resources Information Center

    Shea, Stephen

    2012-01-01

    The blue-eyed islanders puzzle is an old and challenging logic puzzle. This is a narrative of an experience introducing a variation of this puzzle on the first day of classes in a liberal arts mathematics course for non-majors. I describe an exercise that was used to facilitate the class's understanding of the puzzle.

  16. Teaching the Blue-Eyed Islanders Puzzle in a Liberal Arts Mathematics Course

    ERIC Educational Resources Information Center

    Shea, Stephen

    2012-01-01

    The blue-eyed islanders puzzle is an old and challenging logic puzzle. This is a narrative of an experience introducing a variation of this puzzle on the first day of classes in a liberal arts mathematics course for non-majors. I describe an exercise that was used to facilitate the class's understanding of the puzzle.

  17. Decay of Engelmann spruce in the Blue Mountains of Oregon and Washington.

    Treesearch

    Paul E. Aho

    1971-01-01

    A total of 292 Engelmann spruce were dissected and examined for decay and other defects in seven areas in the Blue Mountains of southeastern Washington and northeastern Oregon. Decay on a cubic-foot basis was 3.3 percent for pole trees and 5.4 percent for sawtimber. Defect loss in sawtimber spruce amounted to nearly 12 percent of the gross merchantable board-foot...

  18. Blue light's effects on rhodopsin: photoreversal of bleaching in living rat eyes.

    PubMed

    Grimm, C; Remé, C E; Rol, P O; Williams, T P

    2000-11-01

    To determine whether blue light induces photoreversal of rhodopsin bleaching in vivo. Eyes of anesthetized albino rats were exposed to either green (550 nm) or deep blue (403 nm) light, and the time course of rhodopsin bleaching was determined. Rhodopsin was isolated from whole retinas by detergent extraction and measured photometrically. To inhibit photoreversal of bleaching, rats were perfused with 70 mM hydroxylamine (NH(2)OH), a known inhibitor of photoreversal. To determine whether blue-absorbing, photoreversible photoproducts were formed, rhodopsin was bleached to near completion with green light and then exposed to blue light. Finally, experimental results were simulated on a computer by means of a simple, three-component model involving a long-lived photoreversible photoproduct. Photoreversal of bleaching in blue light occurs in vivo as evidenced by the following: In the absence of NH(2)OH, bleaching of rhodopsin by blue light was slow and complex. In the presence of NH(2)OH, however, blue light bleached rhodopsin very fast with a simple, pseudo-first-order kinetic. A long-lived bleaching intermediate produced by green light exposure was photoreversed to rhodopsin by exposure to blue light. The three-component computer model, invoking a blue-absorbing, photoreversible, long-lived intermediate accurately described the data. Because of the instantaneous, nonmetabolic regeneration of rhodopsin by the process of photoreversal of bleaching, blue light exposure permits the absorption of large numbers of photons by rhodopsin and by a photoreversible intermediate of bleaching in vivo. These data may have an important impact on resolving mechanisms of blue light-mediated damage to the retina.

  19. Space-time modelling of lightning-caused ignitions in the Blue Mountains, Oregon

    USGS Publications Warehouse

    Diaz-Avalos, Carlos; Peterson, D.L.; Alvarado, Ernesto; Ferguson, Sue A.; Besag, Julian E.

    2001-01-01

    Generalized linear mixed models (GLMM) were used to study the effect of vegetation cover, elevation, slope, and precipitation on the probability of ignition in the Blue Mountains, Oregon, and to estimate the probability of ignition occurrence at different locations in space and in time. Data on starting location of lightning-caused ignitions in the Blue Mountains between April 1986 and September 1993 constituted the base for the analysis. The study area was divided into a pixela??time array. For each pixela??time location we associated a value of 1 if at least one ignition occurred and 0 otherwise. Covariate information for each pixel was obtained using a geographic information system. The GLMMs were fitted in a Bayesian framework. Higher ignition probabilities were associated with the following cover types: subalpine herbaceous, alpine tundra, lodgepole pine (Pinus contorta Dougl. ex Loud.), whitebark pine (Pinus albicaulis Engelm.), Engelmann spruce (Picea engelmannii Parry ex Engelm.), subalpine fir (Abies lasiocarpa (Hook.) Nutt.), and grand fir (Abies grandis (Dougl.) Lindl.). Within each vegetation type, higher ignition probabilities occurred at lower elevations. Additionally, ignition probabilities are lower in the northern and southern extremes of the Blue Mountains. The GLMM procedure used here is suitable for analysing ignition occurrence in other forested regions where probabilities of ignition are highly variable because of a spatially complex biophysical environment.

  20. Eye problems in mountain and remote areas: prevention and onsite treatment--official recommendations of the International Commission for Mountain Emergency Medicine ICAR MEDCOM.

    PubMed

    Ellerton, John A; Zuljan, Igor; Agazzi, Giancelso; Boyd, Jeffrey J

    2009-01-01

    Although eyes are not frequently injured in the mountains, they are exposed to many adverse factors from the environment. This article, intended for first responders, paramedics, physicians, and mountaineers, is the consensus opinion of the International Commission for Mountain Emergency Medicine (ICAR-MEDCOM). Its aim is to give practical advice on the management of eye problems in mountainous and remote areas. Snow blindness and minor injuries, such as conjunctival and corneal foreign bodies, could immobilize a person and put him or her at risk of other injuries. Blunt or penetrating trauma can result in the loss of sight in the eye; this may be preventable if the injury is managed properly. In almost all cases of severe eye trauma, protecting the eye and arranging an immediate evacuation are necessary. The most common eye problems, however, are due to ultraviolet light and high altitude. People wearing contact lenses and with previous history of eye diseases are more vulnerable. Any sight-threatening eye problem or unexplained visual loss at high altitude necessitates descent. Wearing appropriate eye protection, such as sunglasses with sidepieces and goggles with polarized or photochromic lenses, could prevent most of the common eye problems in mountaineering.

  1. Estimates of the values of elk in the Blue Mountains of Oregon and Washington: evidence from existing literature.

    Treesearch

    N.A. Bolon

    1994-01-01

    Existing literature was used to estimate the economic value of elk to hunters and wildlife watchers, and the economic impact on personal income to local communities in the Blue Mountains (Blues) of Oregon and Washington. An annual survey of hunters at the Starkey Experimental Forest and Range provided data for estimated elk hunting values and expenditure impacts. The...

  2. Composite Sunrise Butte pluton: Insights into Jurassic–Cretaceous collisional tectonics and magmatism in the Blue Mountains Province, northeastern Oregon

    USGS Publications Warehouse

    Johnson, Kenneth H.; Schwartz, J.J.; Žák, Jiří; Verner, Krystof; Barnes, Calvin G.; Walton, Clay; Wooden, Joseph L.; Wright, James E.; Kistler, Ronald W.

    2015-01-01

    The composite Sunrise Butte pluton, in the central part of the Blue Mountains Province, northeastern Oregon, preserves a record of subduction-related magmatism, arc-arc collision, crustal thickening, and deep-crustal anatexis. The earliest phase of the pluton (Desolation Creek unit) was generated in a subduction zone environment, as the oceanic lithosphere between the Wallowa and Olds Ferry island arcs was consumed. Zircons from this unit yielded a 206Pb/238U age of 160.2 ± 2.1 Ma. A magmatic lull ensued during arc-arc collision, after which partial melting at the base of the thickened Wallowa arc crust produced siliceous magma that was emplaced into metasedimentary rocks and serpentinite of the overthrust forearc complex. This magma crystallized to form the bulk of the Sunrise Butte composite pluton (the Sunrise Butte unit; 145.8 ± 2.2 Ma). The heat necessary for crustal anatexis was supplied by coeval mantle-derived magma (the Onion Gulch unit; 147.9 ± 1.8 Ma).The lull in magmatic activity between 160 and 148 Ma encompasses the timing of arc-arc collision (159–154 Ma), and it is similar to those lulls observed in adjacent areas of the Blue Mountains Province related to the same shortening event. Previous researchers have proposed a tectonic link between the Blue Mountains Province and the Klamath Mountains and northern Sierra Nevada Provinces farther to the south; however, timing of Late Jurassic deformation in the Blue Mountains Province predates the timing of the so-called Nevadan orogeny in the Klamath Mountains. In both the Blue Mountains Province and Klamath Mountains, the onset of deep-crustal partial melting initiated at ca. 148 Ma, suggesting a possible geodynamic link. One possibility is that the Late Jurassic shortening event recorded in the Blue Mountains Province may be a northerly extension of the Nevadan orogeny. Differences in the timing of these events in the Blue Mountains Province and the Klamath–Sierra Nevada Provinces suggest that

  3. Fault-related fluid flow, Beech Mountain thrust sheet, Blue Ridge Province, Tennessee-North Carolina

    SciTech Connect

    Waggoner, W.K.; Mora, C.I. . Dept. of Geological Sciences)

    1992-01-01

    The latest proterozoic Beech Granite is contained within the Beech Mountain thrust sheet (BMTS), part of a middle-late Paleozoic thrust complex located between Mountain City and Grandfather Mountain windows in the western Blue Ridge of TN-NC. At the base of the BMTS, Beech Granite is juxtaposed against lower Paleozoic carbonate and elastics of the Rome Fm. along the Stone Mountain thrust on the southeaster margin of the Mountain City window. At the top of the BMTS, Beech Granite occurs adjacent to Precambrian mafic rocks of the Pumpkin Patch thrust sheet (PPTS). The Beech Granite is foliated throughout the BMTS with mylonitization and localized cataclasis occurring within thrust zones along the upper and lower margins of the BMTS. Although the degree of mylonitization and cataclasis increases towards the thrusts, blocks of relatively undeformed granite also occur within these fault zones. Mylonites and thrusts are recognized as conduits for fluid movement, but the origin of the fluids and magnitude and effects of fluid migration are not well constrained. This study was undertaken to characterize fluid-rock interaction within the Beech Granite and BMTS. Extensive mobility of some elements/compounds within the thrust zones, and the isotopic and mineralogical differences between the thrust zones and interior of the BMTS indicate that fluid flow was focused within the thrust zones. The wide range of elevated temperatures (400--710 C) indicated by qz-fsp fractionations suggest isotopic disequilibrium. Using a more likely temperature range of 300--400 C for Alleghanian deformation, calculated fluid compositions indicate interactions with a mixture of meteoric-hydrothermal and metamorphic water with delta O-18 = 2.6--7.5[per thousand] for the upper thrust zone and 1.3 to 6.2[per thousand] for the lower thrust zone. These ranges are similar to isotopic data reported for other Blue Ridge thrusts and may represent later periods of meteoric water influx.

  4. Distribution of albumin in the normal monkey eye as revealed by Evans blue fluorescence microscopy.

    PubMed

    Radius, R L; Anderson, D R

    1980-03-01

    Since intravenously injected Evans blue binds irreversibly to serum albumin, its distribution reflects albumin exchange between the intravascular and extravascular tissue compartments. In histologic specimens examined by fluorescence, microscopy, extravasated Evans blue--albumin complex was identified within the ciliary body and trabecular meshwork of normal monkey eyes. In eyes fixed by intra-arterial perfusion of fixative, no dye was identified in the choroid, retina, or optic nerve. With immersion fixation, however, some extravasation was seen in the choroid and adjacent optic nerve. In some specimens, the optic nerve was stained not only with material apparently leaking from the choroid but also from a breakdown of the blood-brain barrier in the major disc vasculature during the interval before fixative penetrates into the tissue. Perfusion fixation must be used to avoid this artifact, and freezing techniques would be even better.

  5. Photochemical injury to the foveomacula of the monkey eye following argon blue-green panretinal photocoagulation.

    PubMed Central

    Parver, L M

    2000-01-01

    PURPOSE: Visual loss following panretinal photocoagulation was found in the Diabetic Retinopathy and the Early Treatment Diabetic Retinopathy Studies. This study was designed to test the hypothesis that light scattered in the monkey eye during a procedure designed to mimic a clinical panretinal photocoagulation (PRP) can produce a photochemical injury to the foveomacula. METHODS: Ten eyes of 5 adult cynomologous monkeys underwent a PRP using an argon blue-green laser. Three eyes in 2 monkeys underwent a sham PRP, and an additional eye had a PRP with blue filtered slit-lamp illumination. The animals had baseline fundus photographs and fluorescein angiograms that were repeated 24 hours after the experimental procedure. Forty-eight hours after the experimental procedure, the eyes were removed and processed for light and electron microscopy. RESULTS: There were no observable changes in the macula on fundus photography or fluorescein angiography 24 hours following PRP. Light and electron microscopy demonstrated changes in the retinal pigment epithelium and the outer photoreceptors, which were confined to the foveola. The control eyes showed no apparent effect from the slit lamp illumination used during the PRP. CONCLUSIONS: The presence of histologic evidence of retinal injury in the foveomacula of the monkey eye after a procedure designed to mimic clinical PRP supports the hypothesis that photochemical retinal damage in the foveola may be associated with this procedure. Images FIGURE 1A FIGURE 1B FIGURE 1C FIGURE 1D FIGURE 1E FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 PMID:11190033

  6. Ethical and Pedagogical Issues in the Use of Simulation Activities in the Classroom: Evaluating the "Blue Eyes-Brown Eyes" Prejudice Simulation.

    ERIC Educational Resources Information Center

    Byrnes, Deborah A.; Kiger, Gary

    The effectiveness of a well-known prejudice-reduction simulation activity, "Blue Eyes-Brown Eyes," was assessed as a tool for changing the attitudes of nonblack teacher education students toward blacks. The subjects were 164 students enrolled in eight sections of an introductory elementary education course at a state university. Three…

  7. Late Quaternary landscape evolution at Flat Laurel Gap, Blue Ridge Mountains, North Carolina

    NASA Astrophysics Data System (ADS)

    Shafer, David S.

    1988-07-01

    Analysis of colluvial, fluvial, and bog sediments at Flat Laurel Gap (1500 m) in the Blue Ridge Mountains of North Carolina provides a record of late Quaternary landscape evolution. Thermoluminescence (TL) analysis provides the first absolute-age determinations available for presumed periglacial deposits in the southern Appalachian Mountains. The Pleistocene/Holocene transition, dated between 11,900 and 10,100 yr B.P., represents a period of climatic amelioration and a change from colluvial to alluvial processes. A TL date of 7400 ± 1000 yr B.P. for matrix within a block-stream indicates possible early Holocene reworking of Pleistocene periglacial colluvium. Organic sediment deposition in a bog that began about 3400 yr B.P. increased in rate from 0.02 to 0.09 cm/yr with the onset of logging and land clearance about 1880 A.D.

  8. Regional Integrated Lake-Watershed Acidification Study (RILWAS): Major findings for Adirondack and Blue Ridge Mountains

    SciTech Connect

    Gherini, S.A.; Munson, R.K. ); Altwicker, E.; Clesceri, N. ); April, R. ); Chen, C.W. ); Cronan, C.S. ); Driscoll, C.T. ); Johannes, A.H. ); Newton, R.M.

    1989-12-01

    The primary objective of this investigation was to test the hydrologic and chemical theory developed during the Integrated Lake Watershed Acidification Study (ILWAS). A secondary objective was to assess the distribution of fish species among lakes of varying water quality. A total of 24 lake-watershed systems across the Adirondacks served as stuey sites over a period of two years. The US Forest Service's, Coweeta Hydrologic Laboratory, with over 20 years of data, was used to test the ILWAS model on a Blue Ridge mountain stream. 122 refs., 123 figs., 46 tabs.

  9. Blue Mountain and The Gas Rocks: Rear-Arc Dome Clusters on the Alaska Peninsula

    USGS Publications Warehouse

    Hildreth, Wes; Fierstein, Judy; Calvert, Andrew T.

    2007-01-01

    Behind the single-file chain of stratovolcanoes on the Alaska Peninsula, independent rear-arc vents for mafic magmas are uncommon, and for silicic magmas rarer still. We report here the characteristics, compositions, and ages of two andesite-dacite dome clusters and of several nearby basaltic units, all near Becharof Lake and 15 to 20 km behind the volcanic front. Blue Mountain consists of 13 domes (58-68 weight percent SiO2) and The Gas Rocks of three domes (62-64.5 weight percent SiO2) and a mafic cone (52 weight percent SiO2). All 16 domes are amphibole-biotite-plagioclase felsite, and nearly all are phenocryst rich and quartz bearing. Although the two dome clusters are lithologically and chemically similar and only 25 km apart, they differ strikingly in age. The main central dome of Blue Mountain yields an 40Ar/39Ar age of 632?7 ka, and two of the Gas Rocks domes ages of 25.7?1.4 and 23.3?1.2 ka. Both clusters were severely eroded by glaciation; surviving volumes of Blue Mountain domes total ~1 km3, and of the Gas Rocks domes 0.035 km3. Three basaltic vents lie close to The Gas Rocks, another lies just south of Blue Mountain, and a fifth is near the north shore of Becharof Lake. A basaltic andesite vent 6 km southeast of The Gas Rocks appears to be a flank vent of the arc-front center Mount Peulik. The basalt of Ukinrek Maars has been called transitionally alkalic, but all the other basaltic rocks are subalkaline. CO2-rich gas emissions near the eponymous Gas Rocks domes are not related to the 25-ka dacite dome cluster but, rather, to intracrustal degassing of intrusive basalt, one batch of which erupted 3 km away in 1977. The felsic and mafic vents all lie along or near the Bruin Bay Fault where it intersects a broad transverse structural zone marked by topographic, volcanologic, and geophysical discontinuities.

  10. Damage to the forest ecosystem on Blue Mountain from zinc smelting

    USGS Publications Warehouse

    Beyer, W.N.

    1988-01-01

    Emissions from two zinc smelters in Palmerton, Pennsylvania, have caused widespread destruction of the forest on Blue Mountain. There have been striking changes in the species composition and structure of the community of vascular plants, as well as population reductions of lichens, mosses, arthropods inhabiting the letter, and amphibians. Reductions in the populations of decomposers of organic matter have led to an accumulation of litter on the forest floor. Zinc poisoning was diagnosed in a white-tailed deer, and lead poisoning was diagnosed in a shrew. White-tailed deer also contained high concentrations of cadmium.

  11. Boulder streams, debris fans, and Pleistocene climate change in the Blue Ridge Mountains of central Virginia

    SciTech Connect

    Whittecar, G.R.; Ryter, D.W. )

    1992-07-01

    The west slope of the Blue Ridge mountains in central Virginia is a polygenetic landscape containing interglacial and periglacial features. This paper proposes a general model relating the distribution and origin of hillslope and toeslope Quaternary landforms to climatically influenced geomorphic processes. Two generations of interglacial debris fans in the study area differ in their degree of soil development and clast weathering. Boulder streams, which clog debris flow chutes for the upper debris fans, are interpreted as solifluction features formed during successive periglacial episodes. Growth of the boulder streams and associated talus slopes can influence the magnitude and frequency of debris flows and fan formation during interglacials.

  12. Dental fluorosis in the Blue Mountains and Hawkesbury, New South Wales, Australia: policy implications.

    PubMed

    Bal, Ikreet S; Dennison, Peter J; Evans, R Wendell

    2015-02-01

    The aim of the present study was to determine whether the adjustment of the fluoride concentration to 1 ppm in the drinking water supplied to the Blue Mountains, New South Wales, Australia in 1993 was associated with fluorosis incidence. In 2003, children attending schools in the Blue Mountains and a control region (fluoridated in 1967) that had been randomly selected at baseline in 1992 were examined for dental fluorosis (maxillary central incisors only) using Dean's index. A fluoride history for each child was obtained by questionnaire. Associations between fluorosis and 58 potential explanatory variables were explored. The response rate was 63%. A total of 1138 children aged from 7 to 11 years with erupted permanent central incisors were examined for dental fluorosis. Fluorosis prevalence was the same in both regions. The Community Index of Dental Fluorosis values were slightly different, but were both above 0.6, indicative of public health concern. For the group as a whole, we concluded that: (a) fluorosis prevalence (0.39) in both regions was similar; and (b) the higher-than-expected prevalence and severity of fluorosis was due mainly to two factors: (a) the higher-than-optimal fluoride level in drinking water; and (b) swallowing of fluoride toothpaste in early childhood. © 2014 Wiley Publishing Asia Pty Ltd.

  13. The genetic inheritance of the blue-eyed white phenotype in alpacas (Vicugna pacos).

    PubMed

    Jackling, Felicity C; Johnson, Warren E; Appleton, Belinda R

    2014-01-01

    White-spotting patterns in mammals can be caused by mutations in the gene KIT, whose protein is necessary for the normal migration and survival of melanocytes from the neural crest. The alpaca (Vicugna pacos) blue-eyed white (BEW) phenotype is characterized by 2 blue eyes and a solid white coat over the whole body. Breeders hypothesize that the BEW phenotype in alpacas is caused by the combination of the gene causing gray fleece and a white-spotting gene. We performed an association study using KIT flanking and intragenic markers with 40 unrelated alpacas, of which 17 were BEW. Two microsatellite alleles at KIT-related markers were significantly associated (P < 0.0001) with the BEW phenotype (bew1 and bew2). In a larger cohort of 171 related individuals, we identify an abundance of an allele (bew1) in gray animals and the occurrence of bew2 homozygotes that are solid white with pigmented eyes. Association tests accounting for population structure and familial relatedness are consistent with a proposed model where these alleles are in linkage disequilibrium with a mutation or mutations that contribute to the BEW phenotype and to individual differences in fleece color. © The American Genetic Association. 2012. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  14. Evaluating the Role of Boundary Layer Processes on Diurnal Aerosol Concentrations in the Blue Ridge Mountains of Virginia

    NASA Astrophysics Data System (ADS)

    Lee, T. R.; de Wekker, S.

    2009-12-01

    Forecasting air quality in mountainous terrain is a challenging topic. In this study, we aim to understand the diurnal variability of particulate matter, CO, and CO2 in the Shenandoah National Park (SNP) located in the Blue Ridge Mountains of Virginia. We focus on the effect of atmospheric boundary layer (ABL) dynamics on the diurnal aerosol variability using a combination of observations and numerical modeling. Boundary layer dynamics in mountainous terrain is complicated by a variety of factors such as terrain-induced wind flows. These flows can have a significant impact on atmospheric chemistry but are not well resolved in current air quality forecasting models. In this research, we seek to 1) measure and simulate the diurnal evolution of the ABL at a mountaintop site in the Blue Ridge Mountains, 2) investigate the effect of ABL dynamics on aerosol and CO concentrations on clear days, and 3) investigate the transport of aerosols and pollutants by local, regional, and synoptic-scale flows to the mountaintop using the FLEXPART particle dispersion model and WRF-CHEM model. WRF-CHEM will be run with and without chemistry to isolate the effects of boundary layer dynamics and aerosol formation on diurnal aerosol variability. The results of this study will be incorporated into a diagnostic air quality forecast model for SNP. Measurements come from a 17-m walkup tower that was established in May 2008 along a ridgeline at an elevation of 1037m (38.61°N, 78.35°W) at Pinnacles in the north-central section of SNP. The tower is outfitted with a suite of instruments, including temperature/humidity sensors, cup and sonic anemometers, radiation sensors, a closed-path CO/CO2 gas analyzer, and particle counter. Also, a portable eye-safe LIDAR system is located on-site. In addition, ozone data are collected at a site located nearby. Preliminary results from select clear days in fall, 2008 indicate that ABL height is an important factor governing CO and CO2 concentrations at

  15. Geophysical studies in the vicinity of Blue Mountain and Pumpernickel Valley near Winnemucca, north-central Nevada

    USGS Publications Warehouse

    Ponce, David A.

    2012-01-01

    From May 2008 to September 2009, the U.S. Geological Survey (USGS) collected data from more than 660 gravity stations, 100 line-km of truck-towed magnetometer traverses, and 260 physical-property sites in the vicinity of Blue Mountain and Pumpernickel Valley, northern Nevada (fig. 1). Gravity, magnetic, and physical-property data were collected to study regional crustal structures as an aid to understanding the geologic framework of the Blue Mountain and Pumpernickel Valley areas, which in general, have implications for mineral- and geothermal-resource investigations throughout the Great Basin.

  16. Geology of the Blue Mountains region of Oregon, Idaho, and Washington; stratigraphy, physiography, and mineral resources of the Blue Mountains region

    USGS Publications Warehouse

    Vallier, T. L.; Brooks, H.C.

    1994-01-01

    PART 1: Stratigraphic and sedimentological analysis of sedimentary sequences from the Wallowa terrane of northeastern Oregon has provided a unique insight into the paleogeography and depositional history of the terrane, as well as establishing important constraints on its tectonic evolution and accretionary history. Its Late Triassic history is considered here by examining the two most important sedimentary units in the Wallowa terrane-the Martin Bridge Limestone and the Hurwal Formation. Conformably overlying epiclastic volcanic rocks of the Seven Devils Group, the Martin Bridge Limestone comprises shallow-water platform carbonate rocks and deeper water, off-platform slope and basin facies. Regional stratigraphic and tectonic relations suggest that the Martin Bridge was deposited in a narrow, carbonate-dominated (forearc?) basin during a lull in volcanic activity. The northern Wallowa platform was a narrow, rimmed shelf delineated by carbonate sand shoals. Interior parts of the shelf were characterized by supratidal to shallow subtidal carbonates and evaporites, which were deposited in a restricted basin. In the southern Wallowa Mountains, lithofacies of the Martin Bridge are primarily carbonate turbidites and debris flow deposits, which accumulated on a carbonate slope apron adjacent to the northern Wallowa rimmed shelf from which they were derived. Drowning of the platform in the latest Triassic, coupled with a renewed influx of volcanically derived sediments, resulted in the progradation of fine-grained turbidites of the Hurwal Formation over the carbonate platform. Within the Hurwal, Norian conglomerates of the Excelsior Gulch unit contain exotic clasts of radiolarian chert, which were probably derived from the Bakei terrane. Such a provenance provides evidence of a tectonic link between the Baker and Wallowa terranes as early as the Late Triassic, and offers support for the theory that both terranes were part of a more extensive and complex Blue Mountains

  17. Comparative water quality of lightly-and moderately-impacted streams in the southern Blue Ridge Mountains, USA

    Treesearch

    Katie Price; David S. Leigh

    2006-01-01

    For less-developed regions like the Blue Ridge Mountains. data are limited that link basin-scale land use with stream quality. Two pairs of lightly-impacted (90-100% forested) and moderately-impacted (7&80% forested) sub-basins of the upper Little Tennessee River basin in the southern Blue Ridge were identified for comparison. The pairs contain physically similar...

  18. Scleral cross-linking by riboflavin and blue light application in young rabbits: damage threshold and eye growth inhibition.

    PubMed

    Iseli, Hans Peter; Körber, Nicole; Koch, Christian; Karl, Anett; Penk, Anja; Huster, Daniel; Reichenbach, Andreas; Wiedemann, Peter; Francke, Mike

    2016-01-01

    Scleral cross-linking (SXL) by riboflavin and light application has been introduced as a possible treatment to increase scleral tissue stiffness and to inhibit excessive axial elongation of highly myopic eyes. We evaluated an ocular tissue damage threshold for blue light irradiation, and used SXL treatment to induce eye growth inhibition. The sclera of 3-week-old rabbits (39 pigmented and 15 albino rabbits) were treated with different blue light intensities (450 ± 50 nm) and riboflavin. Alterations and a damage threshold were detected in ocular tissues by means of light microscopy and immunohistochemistry. The influence of SXL on the eye growth was examined in 21 young rabbits and was measured by using A-scan ultrasonography, micrometer caliper, and for selected eyes additionally by MR imaging. Light microscopic examinations demonstrated degenerative changes in ocular tissue after irradiation with blue light intensities above 400 mW/cm(2) (with and without riboflavin application). Therefore, that light intensity was defined as the damage threshold. Tissue alteration in retina, choroid, and sclera and activation of retinal microglia cells and Müller cells could be earlier observed at blue light intensities of 150 and 200 mW/cm(2). Albino rabbits were less sensitive to this SXL treatment. A significant reduction of the eye growth could be detected by SXL treatment with the minimal efficient blue light intensity of 15 mW/cm(2) and maintained stable for 24 weeks. SXL with riboflavin and blue light intensities below a defined damage threshold can induce a long lasting growth inhibitory effect on young rabbit eyes. Therefore, SXL might be a realistic approach to inhibit eye elongation in highly myopic eyes.

  19. Beauty in the eye of the beholder: the two blue opsins of lycaenid butterflies and the opsin gene-driven evolution of sexually dimorphic eyes.

    PubMed

    Sison-Mangus, Marilou P; Bernard, Gary D; Lampel, Jochen; Briscoe, Adriana D

    2006-08-01

    Although previous investigations have shown that wing coloration is an important component of social signaling in butterflies, the contribution of opsin evolution to sexual wing color dichromatism and interspecific divergence remains largely unexplored. Here we report that the butterfly Lycaena rubidus has evolved sexually dimorphic eyes due to changes in the regulation of opsin expression patterns to match the contrasting life histories of males and females. The L. rubidus eye contains four visual pigments with peak sensitivities in the ultraviolet (UV; lambdamax=360 nm), blue (B; lambdamax=437 nm and 500 nm, respectively) and long (LW; lambdamax=568 nm) wavelength range. By combining in situ hybridization of cloned opsin-encoding cDNAs with epi-microspectrophotometry, we found that all four opsin mRNAs and visual pigments are expressed in the eyes in a sex-specific manner. The male dorsal eye, which contains only UV and B (lambdamax=437 nm) visual pigments, indeed expresses two short wavelength opsin mRNAs, UVRh and BRh1. The female dorsal eye, which also has the UV and B (lambdamax=437 nm) visual pigments, also contains the LW visual pigment, and likewise expresses UVRh, BRh1 and LWRh mRNAs. Unexpectedly, in the female dorsal eye, we also found BRh1 co-expressed with LWRh in the R3-8 photoreceptor cells. The ventral eye of both sexes, on the other hand, contains all four visual pigments and expresses all four opsin mRNAs in a non-overlapping fashion. Surprisingly, we found that the 500 nm visual pigment is encoded by a duplicate blue opsin gene, BRh2. Further, using molecular phylogenetic methods we trace this novel blue opsin gene to a duplication event at the base of the Polyommatine+Thecline+Lycaenine radiation. The blue opsin gene duplication may help explain the blueness of blue lycaenid butterflies.

  20. Snow interception, accumulation, accumulation, and melt in lodgepole pine forests in the Blue Mountains of eastern Oregon.

    Treesearch

    Norman H. Miner; James M. Trappe

    1957-01-01

    Lodgepole pine (Pinus contorta) forests in the Blue Mountains of eastern Oregon occupy important water-producing lands. These forests generally occur at middle to high elevations on north slopes, where a substantial portion of the precipitation is snow. To learn more about the influence of lodgepole pine forests on accumulation of mow and rate of...

  1. A multi-scale analysis of streamflow response to changes in evapotranspiration and soil hydrology in the Blue Ridge Mountains

    EPA Science Inventory

    A large amount of research exploring the relationship between watershed forest cover and streamflow quantity has been conducted in the southern Blue Ridge Mountains, particularly in association with the USFS Coweeta Hydrologic Laboratory and the Coweeta LTER. However, a clear ans...

  2. Climate change and special habitats in the Blue Mountains: Riparian areas, wetlands, and groundwater-dependent ecosystems [Chapter 7

    Treesearch

    Kathleen A. Dwire; Sabine Mellmann-Brown

    2017-01-01

    In the Blue Mountains, climate change is likely to have significant, long-term implications for freshwater resources, including riparian areas, wetlands (box 7.1), and groundwater-dependent ecosystems (GDEs, box 7.2). Climate change is expected to cause a transition from snow to rain, resulting in diminished snowpack and shifts in streamflow to earlier in the season (...

  3. Changes in forage lichen biomass after insect outbreaks and fuel reduction treatment in the Blue Mountains, Oregon

    Treesearch

    Bruce McCune; Sarah Jovan; Amanda. Hardman

    2008-01-01

    Forage lichens are pendulous, hairlike species eaten by a wide range of mammals. Our overall goal was to estimate losses of Bryoria, a genus of ecologically important forage species, in forests subjected to disease and fuel reduction treatments at Starkey Experimental Forest in the Blue Mountains of northeastern Oregon. Specific objectives were to...

  4. Morphology and channel evolution of small streams in the southern Blue Ridge mountains of western North Carolina

    Treesearch

    David Leigh

    2010-01-01

    Small streams are understudied in the Southern Blue Ridge Mountains, yet they constitute a huge portion of the drainage network and are relevant with respect to human impact on the landscape and stream restoration efforts. Morphologies of 44 streams (0.01 to 20 km2 watersheds) from western North Carolina are characterized and couched in the context of historical...

  5. Pollination ecology and floral function of Brown's peony (Paeonia brownii) in the Blue Mountains of northeastern Oregon

    Treesearch

    Peter Bernhardt; Retha Meier; Nan. Vance

    2013-01-01

    Brown’s peony, Paeonia brownie (Paeoniaceae), is one of only two peony species native to the Western Hemisphere, yet its pollination ecology and breeding system have never been documented. Using flowering individuals of an endemic colony in the Blue Mountains of Oregon, U.S., we investigated the peony’s pollination system and floral function. We...

  6. A multi-scale analysis of streamflow response to changes in evapotranspiration and soil hydrology in the Blue Ridge Mountains

    EPA Science Inventory

    A large amount of research exploring the relationship between watershed forest cover and streamflow quantity has been conducted in the southern Blue Ridge Mountains, particularly in association with the USFS Coweeta Hydrologic Laboratory and the Coweeta LTER. However, a clear ans...

  7. DEVELOPMENT OF A BIRD INTEGRITY INDEX: MEASURING AVIAN RESPONSE TO DISTURBANCE IN THE BLUE MOUNTAINS OF OREGON, USA

    EPA Science Inventory

    The Bird Integrity Index (BII) presented here uses bird assemblage information to assess human impacts to 28 stream reaches in the Blue Mountains of eastern Oregon. Eighty-one candidate metrics were extracted from bird survey data for testing. The metrics represented aspects of ...

  8. Integrating Science into Management of Ecosystems in the Greater Blue Mountains

    NASA Astrophysics Data System (ADS)

    Chapple, Rosalie S.; Ramp, Daniel; Bradstock, Ross A.; Kingsford, Richard T.; Merson, John A.; Auld, Tony D.; Fleming, Peter J. S.; Mulley, Robert C.

    2011-10-01

    Effective management of large protected conservation areas is challenged by political, institutional and environmental complexity and inconsistency. Knowledge generation and its uptake into management are crucial to address these challenges. We reflect on practice at the interface between science and management of the Greater Blue Mountains World Heritage Area (GBMWHA), which covers approximately 1 million hectares west of Sydney, Australia. Multiple government agencies and other stakeholders are involved in its management, and decision-making is confounded by numerous plans of management and competing values and goals, reflecting the different objectives and responsibilities of stakeholders. To highlight the complexities of the decision-making process for this large area, we draw on the outcomes of a recent collaborative research project and focus on fire regimes and wild-dog control as examples of how existing knowledge is integrated into management. The collaborative research project achieved the objectives of collating and synthesizing biological data for the region; however, transfer of the project's outcomes to management has proved problematic. Reasons attributed to this include lack of clearly defined management objectives to guide research directions and uptake, and scientific information not being made more understandable and accessible. A key role of a local bridging organisation (e.g., the Blue Mountains World Heritage Institute) in linking science and management is ensuring that research results with management significance can be effectively transmitted to agencies and that outcomes are explained for nonspecialists as well as more widely distributed. We conclude that improved links between science, policy, and management within an adaptive learning-by-doing framework for the GBMWHA would assist the usefulness and uptake of future research.

  9. Integrating science into management of ecosystems in the Greater Blue Mountains.

    PubMed

    Chapple, Rosalie S; Ramp, Daniel; Bradstock, Ross A; Kingsford, Richard T; Merson, John A; Auld, Tony D; Fleming, Peter J S; Mulley, Robert C

    2011-10-01

    Effective management of large protected conservation areas is challenged by political, institutional and environmental complexity and inconsistency. Knowledge generation and its uptake into management are crucial to address these challenges. We reflect on practice at the interface between science and management of the Greater Blue Mountains World Heritage Area (GBMWHA), which covers approximately 1 million hectares west of Sydney, Australia. Multiple government agencies and other stakeholders are involved in its management, and decision-making is confounded by numerous plans of management and competing values and goals, reflecting the different objectives and responsibilities of stakeholders. To highlight the complexities of the decision-making process for this large area, we draw on the outcomes of a recent collaborative research project and focus on fire regimes and wild-dog control as examples of how existing knowledge is integrated into management. The collaborative research project achieved the objectives of collating and synthesizing biological data for the region; however, transfer of the project's outcomes to management has proved problematic. Reasons attributed to this include lack of clearly defined management objectives to guide research directions and uptake, and scientific information not being made more understandable and accessible. A key role of a local bridging organisation (e.g., the Blue Mountains World Heritage Institute) in linking science and management is ensuring that research results with management significance can be effectively transmitted to agencies and that outcomes are explained for nonspecialists as well as more widely distributed. We conclude that improved links between science, policy, and management within an adaptive learning-by-doing framework for the GBMWHA would assist the usefulness and uptake of future research.

  10. Population demography of an endangered lizard, the Blue Mountains Water Skink

    PubMed Central

    2013-01-01

    Background Information on the age structure within populations of an endangered species can facilitate effective management. The Blue Mountains Water Skink (Eulamprus leuraensis) is a viviparous scincid lizard that is restricted to < 40 isolated montane swamps in south-eastern Australia. We used skeletochronology of phalanges (corroborated by mark-recapture data) to estimate ages of 222 individuals from 13 populations. Results These lizards grow rapidly, from neonatal size (30 mm snout-vent length) to adult size (about 70 mm SVL) within two to three years. Fecundity is low (mean 2.9 offspring per litter) and is affected by maternal body length and age. Offspring quality may decline with maternal age, based upon captive-born neonates (older females gave birth to slower offspring). In contrast to its broadly sympatric (and abundant) congener E. tympanum, E. leuraensis is short-lived (maximum 6 years, vs 15 years for E. tympanum). Litter size and offspring size are similar in the two species, but female E. leuraensis reproduce annually whereas many E. tympanum produce litters biennially. Thus, a low survival rate (rather than delayed maturation or low annual fecundity) is the key reason why E. leuraensis is endangered. Our 13 populations exhibited similar growth rates and population age structures despite substantial variation in elevation, geographic location and swamp size. However, larger populations (based on a genetic estimate of effective population size) contained older lizards, and thus a wider variance in ages. Conclusion Our study suggests that low adult survival rates, as well as specialisation on a rare and fragmented habitat type (montane swamps) contribute to the endangered status of the Blue Mountains Water Skink. PMID:23402634

  11. Population demography of an endangered lizard, the Blue Mountains Water Skink.

    PubMed

    Dubey, Sylvain; Sinsch, Ulrich; Dehling, Maximilian J; Chevalley, Maya; Shine, Richard

    2013-02-13

    Information on the age structure within populations of an endangered species can facilitate effective management. The Blue Mountains Water Skink (Eulamprus leuraensis) is a viviparous scincid lizard that is restricted to < 40 isolated montane swamps in south-eastern Australia. We used skeletochronology of phalanges (corroborated by mark-recapture data) to estimate ages of 222 individuals from 13 populations. These lizards grow rapidly, from neonatal size (30 mm snout-vent length) to adult size (about 70 mm SVL) within two to three years. Fecundity is low (mean 2.9 offspring per litter) and is affected by maternal body length and age. Offspring quality may decline with maternal age, based upon captive-born neonates (older females gave birth to slower offspring). In contrast to its broadly sympatric (and abundant) congener E. tympanum, E. leuraensis is short-lived (maximum 6 years, vs 15 years for E. tympanum). Litter size and offspring size are similar in the two species, but female E. leuraensis reproduce annually whereas many E. tympanum produce litters biennially. Thus, a low survival rate (rather than delayed maturation or low annual fecundity) is the key reason why E. leuraensis is endangered. Our 13 populations exhibited similar growth rates and population age structures despite substantial variation in elevation, geographic location and swamp size. However, larger populations (based on a genetic estimate of effective population size) contained older lizards, and thus a wider variance in ages. Our study suggests that low adult survival rates, as well as specialisation on a rare and fragmented habitat type (montane swamps) contribute to the endangered status of the Blue Mountains Water Skink.

  12. The structural effect of intravitreal Brilliant blue G and Indocyanine green in rats eyes.

    PubMed

    Ooi, Y L; Khang, T F; Naidu, M; Fong, K C S

    2013-03-01

    To compare the potential retinal toxicity of two commercially Brilliant blue G dyes (Brilliant Peel and Ocublue Plus) and Indocyanine green (ICG) at usual clinical concentration. Brilliant Peel 0.025% (n=9), Ocublue Plus 0.025% (n=9), and ICG 0.05% (n=9) were injected intravitreally into Sprague-Dawley rat left eyes with balanced salt solution injected in the contralateral eyes as control. Evaluation of the effect of the dyes on retinal architecture was done by histological analysis of neurosensory retinal thickness and retinal ganglion cell (RGC) counts 7 days after intravitreal injection. Paired t-test was done to detect the presence of biologically significant thinning in neurosensory retina and five retinal layers for each dye (paired t-tests). One-way ANOVA and Tukey's Honestly Significant Difference test were used to assess whether different dyes caused significant thinning in mean neurosensory retinal thickness and reduction of mean RGC density. Eyes treated with ICG had significantly thinner mean total neurosensory retinal thickness compared with the control eyes (P-value=0.01), followed by those treated with Ocublue Plus (P-value=0.03). Brilliant Peel did not cause significant thinning in any of the five retinal layers (all P-values>0.05). No significant difference in mean thinning of the total retinal thickness was detected between dyes (P-value=0.11). The mean thickness of the photoreceptor outer segment and outer plexiform layers were significantly reduced in ICG-injected eyes when compared with the control eyes (P-value=0.02). No significant difference in mean thinning between the three dyes was detected at all five retinal layers using one-way ANOVA (all P-values>0.35). RGC density was significantly reduced for ICG (P-value=0.01) but only marginally for Ocublue Plus (P-value=0.05). No significant reduction in RGC density was observed for Brilliant Peel (P-value=0.2). Intravitreal Brilliant Peel is safe to rats retina. The retinal thinning and

  13. The structural effect of intravitreal Brilliant blue G and Indocyanine green in rats eyes

    PubMed Central

    Ooi, Y L; Khang, T F; Naidu, M; Fong, K C S

    2013-01-01

    Purpose To compare the potential retinal toxicity of two commercially Brilliant blue G dyes (Brilliant Peel and Ocublue Plus) and Indocyanine green (ICG) at usual clinical concentration. Methods Brilliant Peel 0.025% (n=9), Ocublue Plus 0.025% (n=9), and ICG 0.05% (n=9) were injected intravitreally into Sprague–Dawley rat left eyes with balanced salt solution injected in the contralateral eyes as control. Evaluation of the effect of the dyes on retinal architecture was done by histological analysis of neurosensory retinal thickness and retinal ganglion cell (RGC) counts 7 days after intravitreal injection. Paired t-test was done to detect the presence of biologically significant thinning in neurosensory retina and five retinal layers for each dye (paired t-tests). One-way ANOVA and Tukey's Honestly Significant Difference test were used to assess whether different dyes caused significant thinning in mean neurosensory retinal thickness and reduction of mean RGC density. Results Eyes treated with ICG had significantly thinner mean total neurosensory retinal thickness compared with the control eyes (P-value=0.01), followed by those treated with Ocublue Plus (P-value=0.03). Brilliant Peel did not cause significant thinning in any of the five retinal layers (all P-values>0.05). No significant difference in mean thinning of the total retinal thickness was detected between dyes (P-value=0.11). The mean thickness of the photoreceptor outer segment and outer plexiform layers were significantly reduced in ICG-injected eyes when compared with the control eyes (P-value=0.02). No significant difference in mean thinning between the three dyes was detected at all five retinal layers using one-way ANOVA (all P-values>0.35). RGC density was significantly reduced for ICG (P-value=0.01) but only marginally for Ocublue Plus (P-value=0.05). No significant reduction in RGC density was observed for Brilliant Peel (P-value=0.2). Conclusion Intravitreal Brilliant Peel is safe to rats

  14. Characteristics of thrust fault imbrication near the frontal edge of the Blue Ridge thrust sheet, Buffalo Mountain, Tennessee

    SciTech Connect

    Duddy, M.M.; Woodward, N.B.

    1985-01-01

    The Buffalo Mountain thrust sheet, located along the western margin of the Blue Ridge in northeastern Tennessee, provides an excellent opportunity to examine transitional structural styles and deformation mechanisms between the Valley and Ridge and Blue Ridge. Previous interpretation suggests that, because of pre-fault tilting, thrust faults within the Buffalo Mountain complex cut down stratigraphic section. Geometric data from the present study indicate, however, that the thrust faults cut up section with stratigraphic separations of up to 16,500'. Footwall and hanging wall bedding orientations reveal a stair-step thrust geometry; the Unicoi Fm. (basal Chilhowee Gp. quartzite) is a hanging wall flat, and the Knox Gp. (Cambro-Ordovician carbonate) is a footwall ramp. Ductile and brittle deformation mechanisms are represented by mesofabric elements. Important deformation mechanisms and elements include: flexural slip and flexural flow folding styles, pressure solution cleavage, extensional and contractional fractures, quartz filled tensional fractures and cataclastic fault zones. Although previous workers have determined that thrusting within the Blue Ridge occurs in an out-of-sequence pattern, the Buffalo Mountain thrust complex provides an example of in-sequence thrusting. Thus, based on this example, deformation styles and mechanisms within the Blue Ridge appear to be similar to Valley and Ridge deformation styles and mechanisms.

  15. Non-systematic weathering profile in the Blue Ridge Mountains, N. C. : Role of geochemical variables

    SciTech Connect

    Ciampone, M.A.; McVey, D.E.; Gerke, T.L.; Briggs, W.D.; Zhang, Yangsheng; Maynard, J.B.; Huff, W.D. . Dept. of Geology)

    1992-01-01

    Weathering profiles from representative cores of the Coweeta Group, schist, and Tallulah Falls Fm, gneiss, in the Blue Ridge Mountains of North Carolina were examined. The predominant alteration minerals, which formed from the partial alteration of biotite and plagioclase, include kaolinite, chlorite, vermiculite interstratified with biotite, gibbsite. These mineral phases were identified using petrographic observation, SEM, X-ray diffraction, and selected electron microprobe analysis. These minerals commonly represent a weathering profile (developed from surface to depth on a single source rock) ranging from mature (gibbsite), to intermediate (kaolinite + interlayered biotite/vermiculite), to immature (plagioclase + biotite) at depth. In this study, however, there is no clear vertical zonation of the weathering profile. This indicates a more selective weathering process than would typically be assumed. This nonsystematic weathering profile may reflect variations in bulk composition of the parent rock and/or variations in the composition of ground water. The presence and abundance of gibbsite in these weathering profiles is unusual because it is normally associated with bauxite in which the Al[sub 2]O[sub 3] content is > 80 wt.%. In this study the Al[sub 2]O[sub 3] content of the regolith is approximately 20 wt.%. The presence of gibbsite emphasizes the importance of solution-reprecipitation of Al-rich phases as an independent process in temperature climates, and suggests the activity of silica is more critical than regional climatological effects in controlling regolith formation.

  16. Adapting Natural Resource Management to Climate Change: The Blue Mountains and Northern Rockies Adaptation Partnerships

    NASA Astrophysics Data System (ADS)

    Halofsky, J.; Peterson, D. L.

    2014-12-01

    Concrete ways to adapt to climate change are needed to help natural resource managers take the first steps to incorporate climate change into management and take advantage of opportunities to balance the negative effects of climate change. We recently initiated two science-management climate change adaptation partnerships, one with three national forests and other key stakeholders in the Blue Mountains region of northeastern Oregon, and the other with 16 national forests, three national parks and other stakeholders in the northern Rockies region. Goals of both partnerships were to: (1) synthesize published information and data to assess the exposure, sensitivity, and adaptive capacity of key resource areas, including water use, infrastructure, fisheries, and vegetation and disturbance; (2) develop science-based adaptation strategies and tactics that will help to mitigate the negative effects of climate change and assist the transition of biological systems and management to a warmer climate; (3) ensure adaptation strategies and tactics are incorporated into relevant planning documents; and (4) foster an enduring partnership to facilitate ongoing dialogue and activities related to climate change in the partnerships regions. After an initial vulnerability assessment by agency and university scientists and local resource specialists, adaptation strategies and tactics were developed in a series of scientist-manager workshops. The final vulnerability assessments and adaptation actions are incorporated in technical reports. The partnerships produced concrete adaptation options for national forest and other natural resource managers and illustrated the utility of place-based vulnerability assessments and scientist-manager workshops in adapting to climate change.

  17. Discovery of meteorites on a blue-ice field near the Frontier Mountains, North Victoria Land, Antarctica

    NASA Technical Reports Server (NTRS)

    Delisle, G.; Hoefle, H. C.; Thierbach, R.; Schultz, L.

    1986-01-01

    A high concentration of meteorites were discovered on a blue ice field northeast of the Frontier Mountains. As a result of a systematic search, a total of 42 meteorites were recovered. The current glacial situation has evolved through various stages, which are discussed in relationship to the concentration of meteorites. Ice flow patterns are summarized. The chemical composition and terrestrial ages of the meteorites are discussed.

  18. Damage threshold in adult rabbit eyes after scleral cross-linking by riboflavin/blue light application.

    PubMed

    Iseli, Hans Peter; Körber, Nicole; Karl, Anett; Koch, Christian; Schuldt, Carsten; Penk, Anja; Liu, Qing; Huster, Daniel; Käs, Josef; Reichenbach, Andreas; Wiedemann, Peter; Francke, Mike

    2015-10-01

    Several scleral cross-linking (SXL) methods were suggested to increase the biomechanical stiffness of scleral tissue and therefore, to inhibit axial eye elongation in progressive myopia. In addition to scleral cross-linking and biomechanical effects caused by riboflavin and light irradiation such a treatment might induce tissue damage, dependent on the light intensity used. Therefore, we characterized the damage threshold and mechanical stiffening effect in rabbit eyes after application of riboflavin combined with various blue light intensities. Adult pigmented and albino rabbits were treated with riboflavin (0.5 %) and varying blue light (450 ± 50 nm) dosages from 18 to 780 J/cm(2) (15 to 650 mW/cm(2) for 20 min). Scleral, choroidal and retinal tissue alterations were detected by means of light microscopy, electron microscopy and immunohistochemistry. Biomechanical changes were measured by shear rheology. Blue light dosages of 480 J/cm(2) (400 mW/cm(2)) and beyond induced pathological changes in ocular tissues; the damage threshold was defined by the light intensities which induced cellular degeneration and/or massive collagen structure changes. At such high dosages, we observed alterations of the collagen structure in scleral tissue, as well as pigment aggregation, internal hemorrhages, and collapsed blood vessels. Additionally, photoreceptor degenerations associated with microglia activation and macroglia cell reactivity in the retina were detected. These pathological alterations were locally restricted to the treated areas. Pigmentation of rabbit eyes did not change the damage threshold after a treatment with riboflavin and blue light but seems to influence the vulnerability for blue light irradiations. Increased biomechanical stiffness of scleral tissue could be achieved with blue light intensities below the characterized damage threshold. We conclude that riboflavin and blue light application increased the biomechanical stiffness of scleral tissue at

  19. Mountains

    SciTech Connect

    Fuller, M.

    1989-01-01

    This book covers the following topics: Above the forest: the alpine tundra; Solar energy, water, wind and soil in mountains; Mountain weather; Mountain building and plate tectonics; Mountain walls: forming, changing, and disappearing; Living high: mountain ecosystems; Distribution of mountain plants and animals; On foot in the mountains: how to hike and backpack; Ranges and peaks of the world. Map and guidebook sources, natural history and mountain adventure trips, mountain environmental education centers and programs, and sources of information on trails for the handicapped are included.

  20. Benthic macroinvertebrate responses to increasing levels of cattle grazing in Blue Ridge Mountain streams, Virginia, USA.

    PubMed

    Braccia, Amy; Voshell, J Reese

    2007-08-01

    The relationship between benthic macroinvertebrate assemblages and cattle density was assessed from fall 2002 through spring 2004 in five small streams that represented a gradient of cattle grazing intensity. All study stream reaches were in pasture with no woody riparian vegetation, but varied in the intensity of cattle grazing (0 cattle ha(-1) at site 1 to 2.85 cattle ha(-1) at site 5). Regression analysis indicated highly significant and strong macroinvertebrate metric responses to cattle density during most sampling periods. The majority of metrics responded negatively to increased grazing, while a few (total taxa richness, number of sensitive taxa, and % collector filterers) increased along the gradient before declining at the most heavily grazed sites. Total number of sensitive taxa and % Coleoptera had the strongest relationship with cattle density throughout the study period. During some sampling periods, nearly 80% of the variation in these metrics was explained by cattle density. The elmid beetle, Oulimnius, had a particularly strong negative response to the grazing gradient. Study site groupings based on taxa composition, using detrended correspondence analysis (DCA), indicated that benthic samples collected from the reference site and light rotational grazing site were more similar in macroinvertebrate taxa composition than samples collected from the intermediate grazing and heavy grazing sites. Our findings demonstrate that biological integrity, as measured by benthic macroinvertebrate metrics and assemblage composition, is highly related to cattle density in small streams in the Blue Ridge mountains, Virginia, USA. This suggests that the degree of agricultural intensity should be given consideration in stream assessments, as well as land use planning and regulatory decisions.

  1. Damage to the forest ecosystem on Blue Mountain from zinc smelting

    SciTech Connect

    Beyer, W.N.

    1988-01-01

    Two zinc smelters in Palmerton, Pennsylvania, emitted large amounts of zinc, cadmium, lead, and sulfur dioxide for more than 80 years. A review of the ecological studies done at Lehigh Gap on Blue Mountain yields a comprehensive picture of damage that may result from metal emissions. The most obvious effect has been the destruction of trees, caused by a combination of zinc toxicity and natural stresses. High zinc concentrations in soil inhibited seedling root growth, reducing the number of young trees and hindering regeneration. Effects on the vegetation include stunting, susceptibility to drought, and changes in species and age structure. Communities of lower plants have also been affected. Populations of bacteria, actinomycetes, fungi, and arthropods in soil and litter were reduced. This has led to a reduced rate of litter decomposition and an increased thickness of the horizon. Some strains of microorganisms were tolerant to very high zinc concentrations. Some wild vertebrates, such as amphibians, were virtually absent from sites near to Lehigh Gap. Zinc poisoning was diagnosed in a white-tailed deer with an abnormally high renal zinc concentration and an articular lesion in a hind leg. There was some evidence of lead poisoning of wildlife; a short-tailed shrew had high tissue concentrations, depressed red blood cell delta-aminolevulinic acid dehydratase activity, and renal nuclear inclusion bodies. Some songbirds had highly elevated hepatic lead concentrations. Although Lehigh Gap is extremely contaminated with cadmium, there was no evidence of pathological lesions that could be attributed to cadmium in any of the wild animals examined.

  2. Ecological and economic services provided by birds on Jamaican Blue Mountain coffee farms.

    PubMed

    Kellermann, Jherime L; Johnson, Matthew D; Stercho, Amy M; Hackett, Steven C

    2008-10-01

    Coffee farms can support significant biodiversity, yet intensification of farming practices is degrading agricultural habitats and compromising ecosystem services such as biological pest control. The coffee berry borer (Hypothenemus hampei) is the world's primary coffee pest. Researchers have demonstrated that birds reduce insect abundance on coffee farms but have not documented avian control of the berry borer or quantified avian benefits to crop yield or farm income. We conducted a bird-exclosure experiment on coffee farms in the Blue Mountains, Jamaica, to measure avian pest control of berry borers, identify potential predator species, associate predator abundance and borer reductions with vegetation complexity, and quantify resulting increases in coffee yield. Coffee plants excluded from foraging birds had significantly higher borer infestation, more borer broods, and greater berry damage than control plants. We identified 17 potential predator species (73% were wintering Neotropical migrants), and 3 primary species composed 67% of migrant detections. Average relative bird abundance and diversity and relative resident predator abundance increased with greater shade-tree cover. Although migrant predators overall did not respond to vegetation complexity variables, the 3 primary species increased with proximity to noncoffee habitat patches. Lower infestation on control plants was correlated with higher total bird abundance, but not with predator abundance or vegetation complexity. Infestation of fruit was 1-14% lower on control plants, resulting in a greater quantity of saleable fruits that had a market value of US$44-$105/ha in 2005/2006. Landscape heterogeneity in this region may allow mobile predators to provide pest control broadly, despite localized farming intensities. These results provide the first evidence that birds control coffee berry borers and thus increase coffee yield and farm income, a potentially important conservation incentive for producers.

  3. New antiepileptic medication linked to blue discoloration of the skin and eyes.

    PubMed

    Clark, Sarah; Antell, Alexandra; Kaufman, Kimberly

    2015-02-01

    Ezogabine is an antiepileptic medication approved in June 2011 by the US Food and Drug Administration (FDA) as an adjunctive treatment for partial seizures. Minimal drug interactions and a novel mechanism of action made ezogabine an appealing new treatment option. However, adverse effects reported during clinical trials and following drug approval have been alarming. A Risk Evaluation Mitigation Strategy (REMS) program has been established for urinary retention. A safety alert was published in April 2013 warning ezogabine may cause retinal pigment abnormalities and/or blue-gray discoloration, most notably on or near the lips, nail beds, sclera and conjunctiva with long-term use. In October 2013, the FDA announced a formal label change to ezogabine to include a black boxed warning emphasizing the previously reported warnings of eye and skin discoloration and permanent vision changes. Given the unknown nature of the pathophysiology, consequences and potential for reversibility of these effects, GlaxoSmithKline and the FDA have published recommendations for patients currently receiving ezogabine. Further data from published case reports and long-term safety trials in the future may lend additional insight into these concerning effects.

  4. Blue light induced A2E oxidation in rat eyes--experimental animal model of dry AMD.

    PubMed

    Wielgus, A R; Collier, R J; Martin, E; Lih, F B; Tomer, K B; Chignell, C F; Roberts, J E

    2010-11-01

    Previous studies have shown that short-wavelength blue visible light induces retinal injury and may be a risk factor for age related macular degeneration. A2E is a blue light absorbing retinal chromophore that accumulates with age. Our previous in vitro studies have determined that, although A2E itself has a low phototoxic efficiency, the oxidation products of A2E that are formed in the presence of visible light can contribute to observed retinal pigment epithelial photodamage. The purpose of this study was to investigate the effects of blue light on retinal phototoxicity and its relationship to A2E, oxidized A2E and its isomers. Sprague-Dawley albino rats were dark adapted for 24 h. Control rats remained in the dark while experimental rats were exposed to blue light (λ = 450 nm, 3.1 mW cm(-2)) for 6 h. Isolated retinas were homogenized in Folch extraction mixture and then in chloroform. The dried extracts were reconstituted and divided for determination of organic soluble compound. Esters of fatty acids were determined with GC-MS, A2E and other chromophores using HPLC, and A2E oxidation products with LC-MS. Exposure of rat eyes to blue light did not significantly change the fatty acid composition of the retina. The A2E concentration (normalized to fatty acid content) in blue light exposed animals was found to be lower than the A2E concentration in control rats. The concentrations of all-trans-retinal-ethanolamine adduct and iso-A2E a precursor and an isomer of A2E respectively, were also lower after blue-light exposure than in the retinas of rats housed in the dark. On the other hand, the amount of oxidized forms of A2E was higher in the animals exposed to blue light. We conclude that in the rat eye, blue-light exposure promotes oxidation of A2E and iso-A2E to the products that are toxic to retinal tissue. Although high concentrations of A2E may be cytotoxic to the retina, the phototoxicity associated with blue light damage to the retina is in part a result of

  5. Evolutionary history inferred from the de novo assembly of a nonmodel organism, the blue-eyed black lemur

    PubMed Central

    Meyer, Wynn K; Venkat, Aarti; Kermany, Amir R; van de Geijn, Bryce; Zhang, Sidi; Przeworski, Molly

    2015-01-01

    Lemurs, the living primates most distantly related to humans, demonstrate incredible diversity in behaviour, life history patterns and adaptive traits. Although many lemur species are endangered within their native Madagascar, there is no high-quality genome assembly from this taxon, limiting population and conservation genetic studies. One critically endangered lemur is the blue-eyed black lemur Eulemur flavifrons. This species is fixed for blue irises, a convergent trait that evolved at least four times in primates and was subject to positive selection in humans, where 5′ regulatory variation of OCA2 explains most of the brown/blue eye colour differences. We built a de novo genome assembly for E. flavifrons, providing the most complete lemur genome to date, and a high confidence consensus sequence for close sister species E. macaco, the (brown-eyed) black lemur. From diversity and divergence patterns across the genomes, we estimated a recent split time of the two species (160 Kya) and temporal fluctuations in effective population sizes that accord with known environmental changes. By looking for regions of unusually low diversity, we identified potential signals of directional selection in E. flavifrons at MITF, a melanocyte development gene that regulates OCA2 and has previously been associated with variation in human iris colour, as well as at several other genes involved in melanin biosynthesis in mammals. Our study thus illustrates how whole-genome sequencing of a few individuals can illuminate the demographic and selection history of nonmodel species. PMID:26198179

  6. Evolutionary history inferred from the de novo assembly of a nonmodel organism, the blue-eyed black lemur.

    PubMed

    Meyer, Wynn K; Venkat, Aarti; Kermany, Amir R; van de Geijn, Bryce; Zhang, Sidi; Przeworski, Molly

    2015-09-01

    Lemurs, the living primates most distantly related to humans, demonstrate incredible diversity in behaviour, life history patterns and adaptive traits. Although many lemur species are endangered within their native Madagascar, there is no high-quality genome assembly from this taxon, limiting population and conservation genetic studies. One critically endangered lemur is the blue-eyed black lemur Eulemur flavifrons. This species is fixed for blue irises, a convergent trait that evolved at least four times in primates and was subject to positive selection in humans, where 5' regulatory variation of OCA2 explains most of the brown/blue eye colour differences. We built a de novo genome assembly for E. flavifrons, providing the most complete lemur genome to date, and a high confidence consensus sequence for close sister species E. macaco, the (brown-eyed) black lemur. From diversity and divergence patterns across the genomes, we estimated a recent split time of the two species (160 Kya) and temporal fluctuations in effective population sizes that accord with known environmental changes. By looking for regions of unusually low diversity, we identified potential signals of directional selection in E. flavifrons at MITF, a melanocyte development gene that regulates OCA2 and has previously been associated with variation in human iris colour, as well as at several other genes involved in melanin biosynthesis in mammals. Our study thus illustrates how whole-genome sequencing of a few individuals can illuminate the demographic and selection history of nonmodel species.

  7. Photoresponses of the compound eye of the sandhopper Talitrus saltator (Crustacea, Amphipoda) in the ultraviolet-blue range.

    PubMed

    Ugolini, A; Borgioli, G; Galanti, G; Mercatelli, L; Hariyama, T

    2010-08-01

    The semi-terrestrial sandhopper Talitrus saltator uses celestial visual cues to orient along the sea-land axis of the beach. Previous spectral-filtering experiments suggested that it perceives directional information from wavelengths in the ultraviolet (UV)-blue range. Binary choice experiments between dark and UV (380-nm) light carried out on dark-adapted individuals of T. saltator showed photopositive movement to UV. Morphologically, each ommatidium in the eye consists of five retinula cells, four large and one small. In electroretinogram experiments, sensitivity of the dark-adapted eye is dominated by a receptor maximally sensitive at about 390-450 nm and secondarily sensitive at about 500-550 nm. Selective light-adaptation experiments at 580 nm showed the apparent sensitivity decreasing at around the secondary sensitive range, thus disclosing the existence of UV-blue photoreceptor cells. Here the existence of UV-blue detection is confirmed, and evidence is provided that green and UV-blue visual pigments are located in the large and small retinula cells, respectively.

  8. Crustal structure beneath the Blue Mountains terranes and cratonic North America, eastern Oregon, and Idaho, from teleseismic receiver functions

    NASA Astrophysics Data System (ADS)

    Christian Stanciu, A.; Russo, Raymond M.; Mocanu, Victor I.; Bremner, Paul M.; Hongsresawat, Sutatcha; Torpey, Megan E.; VanDecar, John C.; Foster, David A.; Hole, John A.

    2016-07-01

    We present new images of lithospheric structure obtained from P-to-S conversions defined by receiver functions at the 85 broadband seismic stations of the EarthScope IDaho-ORegon experiment. We resolve the crustal thickness beneath the Blue Mountains province and the former western margin of cratonic North America, the geometry of the western Idaho shear zone (WISZ), and the boundary between the Grouse Creek and Farmington provinces. We calculated P-to-S receiver functions using the iterative time domain deconvolution method, and we used the H-k grid search method and common conversion point stacking to image the lithospheric structure. Moho depths beneath the Blue Mountains terranes range from 24 to 34 km, whereas the crust is 32-40 km thick beneath the Idaho batholith and the regions of extended crust of east-central Idaho. The Blue Mountains group Olds Ferry terrane is characterized by the thinnest crust in the study area, 24 km thick. There is a clear break in the continuity of the Moho across the WISZ, with depths increasing from 28 km west of the shear zone to 36 km just east of its surface expression. The presence of a strong midcrustal converting interface at 18 km depth beneath the Idaho batholith extending 20 km east of the WISZ indicates tectonic wedging in this region. A north striking 7 km offset in Moho depth, thinning to the east, is present beneath the Lost River Range and Pahsimeroi Valley; we identify this sharp offset as the boundary that juxtaposes the Archean Grouse Creek block with the Paleoproterozoic Farmington zone.

  9. Anomalous concentrations of several metals in iron-formation of the Blue Lead Mountain area, Pennington County, South Dakota

    USGS Publications Warehouse

    Raymond, William H.; King, Robert Ugstad; Norton, James Jennings

    1975-01-01

    Geochemical sampling of bedrock has revealed anomalous copper, silver, molybdenum, gold, arsenic, mercury, zinc, and cobalt in meta-iron-formation in the Blue Lead Mountain area 5 miles (8 kilometres) north-northwest of Keystone, S. Dak. The anomalies are in complexly folded and faulted iron-formation. Metal content decreases sharply in the surrounding rocks. The extent and intensity of the anomalous areas, despite evidence that previous mining had little success, are sufficient to make this area an interesting target for exploration.

  10. Modification of mixed-conifer forests by ruminant herbivores in the Blue Mountains ecological province.

    Treesearch

    Robert A. Riggs; Arthur R. Tiedemann; John G. Cook; et al.

    2000-01-01

    Secondary plant succession and the accumulation of biomass and nutrients were documented at seven ruminant exclosures in Abies and Pseudotsuga forests variously disturbed by logging, burning, and grass seeding. Long-term (25 or more years) foraging by Rocky Mountain mule deer (Odocoileus hemionus) and Rocky Mountain elk (Cervus elaphus...

  11. Evolution of color vision in pierid butterflies: blue opsin duplication, ommatidial heterogeneity and eye regionalization in Colias erate.

    PubMed

    Awata, Hiroko; Wakakuwa, Motohiro; Arikawa, Kentaro

    2009-04-01

    This paper documents the molecular organization of the eye of the Eastern Pale Clouded Yellow butterfly, Colias erate (Pieridae). We cloned four cDNAs encoding visual pigment opsins, corresponding to one ultraviolet, two blue and one long wavelength-absorbing visual pigments. Duplication of the blue visual pigment class occurs also in another pierid species, Pieris rapae, suggesting that blue duplication is a general feature in the family Pieridae. We localized the opsin mRNAs in the Colias retina by in situ hybridization. Among the nine photoreceptor cells in an ommatidium, R1-9, we found that R3-8 expressed the long wavelength class mRNA in all ommatidia. R1 and R2 expressed mRNAs of the short wavelength opsins in three fixed combinations, corresponding to three types of ommatidia. While the duplicated blue opsins in Pieris are separately expressed in two subsets of R1-2 photoreceptors, one blue sensitive and another violet sensitive, those of Colias appear to be always coexpressed.

  12. Effects of blue light on the circadian system and eye physiology

    PubMed Central

    Ferguson, Ian; Tsubota, Kazuo

    2016-01-01

    Light-emitting diodes (LEDs) have been used to provide illumination in industrial and commercial environments. LEDs are also used in TVs, computers, smart phones, and tablets. Although the light emitted by most LEDs appears white, LEDs have peak emission in the blue light range (400–490 nm). The accumulating experimental evidence has indicated that exposure to blue light can affect many physiologic functions, and it can be used to treat circadian and sleep dysfunctions. However, blue light can also induce photoreceptor damage. Thus, it is important to consider the spectral output of LED-based light sources to minimize the danger that may be associated with blue light exposure. In this review, we summarize the current knowledge of the effects of blue light on the regulation of physiologic functions and the possible effects of blue light exposure on ocular health. PMID:26900325

  13. Effects of blue light on the circadian system and eye physiology.

    PubMed

    Tosini, Gianluca; Ferguson, Ian; Tsubota, Kazuo

    2016-01-01

    Light-emitting diodes (LEDs) have been used to provide illumination in industrial and commercial environments. LEDs are also used in TVs, computers, smart phones, and tablets. Although the light emitted by most LEDs appears white, LEDs have peak emission in the blue light range (400-490 nm). The accumulating experimental evidence has indicated that exposure to blue light can affect many physiologic functions, and it can be used to treat circadian and sleep dysfunctions. However, blue light can also induce photoreceptor damage. Thus, it is important to consider the spectral output of LED-based light sources to minimize the danger that may be associated with blue light exposure. In this review, we summarize the current knowledge of the effects of blue light on the regulation of physiologic functions and the possible effects of blue light exposure on ocular health.

  14. Simultaneous batholith emplacement, terrane/continent collision, and oroclinal bending in the Blue Mountains Province, North American Cordillera

    NASA Astrophysics Data System (ADS)

    Žák, Jiří; Verner, Kryštof; Tomek, Filip; Holub, František V.; Johnson, Kenneth; Schwartz, Joshua J.

    2015-06-01

    The North American Cordillera is a classic example of accretionary orogen, consisting of multiple oceanic terranes attached to the western margin of Laurentia during the Mesozoic times. Although the Cordillera is linear for most parts, terrane boundaries are at a high angle to the overall structural grain in several segments of the orogen, which has been a matter of longstanding controversy as to how and when these orogenic curvatures formed. This paper discusses mechanisms, kinematics, and timing of initiation of one of these major curvatures, the Blue Mountains Province in northeastern Oregon. Here magmatic fabric patterns and anisotropy of magnetic susceptibility in the Wallowa batholith record three phases of progressive deformation of the host Wallowa terrane during Early Cretaceous. First is terrane-oblique ~NE-SW shortening, interpreted as recording attachment of the amalgamated oceanic and fringing terranes to the continental margin during dextral convergence at ~140 Ma. Deformation subsequently switched to pure shear-dominated ~NNE-SSW shortening associated with crustal thickening, caused by continued impingement of the amalgamated Blue Mountains superterrane into a presumed westward concave reentrant in the continental margin at ~135-128 Ma. Upon impingement (at ~126 Ma), the northern portion of the superterrane became "locked," leading to reorientation of the principal shortening direction to ~NNW-SSE while its still deformable southern portion rotated clockwise about a vertical axis. We thus propose oblique bending as the main mechanism of the orocline formation whereby horizontal compressive forces resulting from plate convergence acted at an angle to the terrane boundaries.

  15. Middle Jurassic strata link Wallowa, Olds Ferry, and Izee terranes in the accreted Blue Mountains island arc, northeastern Oregon

    SciTech Connect

    White, J.D.L. ); Vallier, T. ); Stanley, G.D. Jr. ); Ash, S.R. ); White, D.L.

    1992-08-01

    Middle Jurassic strata atop the Wallowa terrane in northeastern Oregon link the Wallowa, Izee, and Olds Ferry terranes as related elements of a single long-lived and complex oceanic feature, the Blue Mountains island arc. Middle Jurassic strata in the Wallowa terrane include a dacitic ash-flow deposit and contain fossil corals and bivalves of North American affinity. Plant fossils in fluvial sandstones support a Jurassic age and indicate a seasonal temperate climate. Corals in a transgressive sequence traditionally overlying the fluvial units are of Bajocian age and are closely related to endemic varieties of the Western Interior embayment. They are unlike Middle Jurassic corals in other Cordilleran terranes; their presence suggests that the Blue Mountains island arc first approached the North American craton at high paleolatitudes in Middle Jurassic time. The authors consider the Bajocian marine strata and underlying fluvial volcaniclastic units to be a basin-margin equivalent of the Izee terrane, a largely Middle Jurassic (Bajocian) succession of basinal volcaniclastic and volcanic rocks known to overlie the Olds Ferry and Baker terranes.

  16. Strategies and recommendations for addressing forest health issues in the Blue Mountains of Oregon and Washington. Forest service general technical report

    SciTech Connect

    Tanaka, J.A.; Starr, G.L.; Quigley, T.M.

    1995-03-01

    The Blue Mountains Natural Resources Institute held three types of meetings to obtain public and scientific input into strategies for addressing forest health issues in the Blue Mountains of Oregon and Washington. Seven strategies are proposed: (2) plan and implement management on a landscape level, (2) enhance training on natural resources, (3) facilitate public involvement in planning and decision making, (4) develop an integrated landscape-level database, (5) develop an integrated monitoring system, (6) assess economic and social effects and assist with adaptation to change, and (7) identify barriers to improving the protesting forest health and recommend changes.

  17. Genetic diversity of Haemonchus contortus isolated from sympatric wild blue sheep (Pseudois nayaur) and sheep in Helan Mountains, China.

    PubMed

    Shen, Dong-Dong; Wang, Ji-Fei; Zhang, Dan-Yu; Peng, Zhi-Wei; Yang, Tian-Yun; Wang, Zhao-Ding; Bowman, Dwight D; Hou, Zhi-Jun; Liu, Zhen-Sheng

    2017-09-19

    Haemonchus contortus is known among parasitic nematodes as one of the major veterinary pathogens of small ruminants and results in great economic losses worldwide. Human activities, such as the sympatric grazing of wild with domestic animals, may place susceptible wildlife hosts at risk of increased prevalence and infection intensity with this common small ruminant parasite. Studies on phylogenetic factors of H. contortus should assist in defining the amount of the impact of anthropogenic factors on the extent of sharing of agents such as this nematode between domestic animals and wildlife. H. contortus specimens (n = 57) were isolated from wild blue sheep (Pseudois nayaur) inhabiting Helan Mountains (HM), China and additional H. contortus specimens (n = 20) were isolated from domestic sheep that were grazed near the natural habitat of the blue sheep. Complete ITS2 (second internal transcribed spacer) sequences and partial sequences of the nad4 (nicotinamide dehydrogenase subunit 4 gene) gene were amplified to determine the sequence variations and population genetic diversities between these two populations. Also, 142 nad4 haplotype sequences of H. contortus from seven other geographical regions of China were retrieved from database to further examine the H. contortus population structure. Sequence analysis revealed 10 genotypes (ITS2) and 73 haplotypes (nad4) among the 77 specimens, with nucleotide diversities of 0.007 and 0.021, respectively, similar to previous studies in other countries, such as Pakistan, Malaysia and Yemen. Phylogenetic analyses (BI, MP, NJ) of nad4 sequences showed that there were no noticeable boundaries among H. contortus populations from different geographical origin and population genetic analyses revealed that most of the variation (94.21%) occurred within H. contortus populations. All phylogenetic analyses indicated that there was little genetic differentiation but a high degree of gene flow among the H. contortus populations among

  18. Don't it make my blue eyes brown: heterochromia and other abnormalities of the iris.

    PubMed

    Rennie, I G

    2012-01-01

    Eye colour is one of the most important characteristics in determining facial appearance. In this paper I shall discuss the anatomy and genetics of normal eye colour, together with a wide and diverse range of conditions that may produce an alteration in normal iris pigmentation or form.

  19. Don't it make my blue eyes brown: heterochromia and other abnormalities of the iris

    PubMed Central

    Rennie, I G

    2012-01-01

    Eye colour is one of the most important characteristics in determining facial appearance. In this paper I shall discuss the anatomy and genetics of normal eye colour, together with a wide and diverse range of conditions that may produce an alteration in normal iris pigmentation or form. PMID:21979861

  20. Pleistocene glaciation in the blue ridge province, southern appalachian mountains, north Carolina.

    PubMed

    Berkland, J O; Raymond, L A

    1973-08-17

    Glacial polish, grooves, and striations discovered at an elevation of 1370 meters in the headwaters of Boone Fork on Grandfather Mountain, North Carolina, indicate the former, existence of alpine glaciation at a latitude of 36 degrees 07'N. The Boone Fork glacier was located 890 kilometers south of the previously recognized southern limit of alpine glaciation in the Appalachian Mountains, and 350 kilometers southeast of the nearest point on the Laurentide ice sheet. This find has significant implications for studies of Pleistocene geomorphology, paleobiology, and paleoclimatology in the eastern United States.

  1. Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression.

    PubMed

    Eiberg, Hans; Troelsen, Jesper; Nielsen, Mette; Mikkelsen, Annemette; Mengel-From, Jonas; Kjaer, Klaus W; Hansen, Lars

    2008-03-01

    The human eye color is a quantitative trait displaying multifactorial inheritance. Several studies have shown that the OCA2 locus is the major contributor to the human eye color variation. By linkage analysis of a large Danish family, we finemapped the blue eye color locus to a 166 Kbp region within the HERC2 gene. By association analyses, we identified two SNPs within this region that were perfectly associated with the blue and brown eye colors: rs12913832 and rs1129038. Of these, rs12913832 is located 21.152 bp upstream from the OCA2 promoter in a highly conserved sequence in intron 86 of HERC2. The brown eye color allele of rs12913832 is highly conserved throughout a number of species. As shown by a Luciferase assays in cell cultures, the element significantly reduces the activity of the OCA2 promoter and electrophoretic mobility shift assays demonstrate that the two alleles bind different subsets of nuclear extracts. One single haplotype, represented by six polymorphic SNPs covering half of the 3' end of the HERC2 gene, was found in 155 blue-eyed individuals from Denmark, and in 5 and 2 blue-eyed individuals from Turkey and Jordan, respectively. Hence, our data suggest a common founder mutation in an OCA2 inhibiting regulatory element as the cause of blue eye color in humans. In addition, an LOD score of Z = 4.21 between hair color and D14S72 was obtained in the large family, indicating that RABGGTA is a candidate gene for hair color.

  2. Mountains

    Treesearch

    Regina M. Rochefort; Laurie L. Kurth; Tara W. Carolin; Robert R. Mierendorf; Kimberly Frappier; David L. Steenson

    2006-01-01

    This chapter concentrates on subalpine parklands and alpine meadows of southern British Columbia, Washington, Oregon, and western Montana. These areas lie on the flanks of several mountain ranges including the Olympics, the Cascades of Oregon and Washington, and the Coast Mountains in British Columbia.

  3. Effects of Watershed Land Use and Geomorphology on Stream Baseflows in the Southern Blue Ridge Mountains

    EPA Science Inventory

    The current understanding of watershed hydrology does not provide insight into prediction of low-flow response to land-use change in developing regions like the Blue Ridge of north Georgia and western North Carolina. To address this problem, three separate but complementary stud...

  4. Effects of Watershed Land Use and Geomorphology on Stream Baseflows in the Southern Blue Ridge Mountains

    EPA Science Inventory

    The current understanding of watershed hydrology does not provide insight into prediction of low-flow response to land-use change in developing regions like the Blue Ridge of north Georgia and western North Carolina. To address this problem, three separate but complementary stud...

  5. Effects of watershed land use and geomorphology on stream low flows during severe drought conditions in the southern Blue Ridge Mountains, Georgia and North Carolina, United States

    Treesearch

    Katie Price; C. Jackson; Albert Parker; Trond Reitan; John Dowd; Mike Cyterski

    2011-01-01

    Land use and physiographic variability influence stream low flows, yet their interactions and relative influence remain unresolved. Our objective was to assess the influence of land use and watershed geomorphic characteristics on low-flow variability in the southern Blue Ridge Mountains of North Carolina and Georgia. Ten minute interval discharge data for 35 streams (...

  6. Regeneration in United States Department of Agriculture Forest Service mixed conifer partial cuttings in the Blue Mountains of Oregon and Washington.

    Treesearch

    K.W. Seidel; S. Conrade. Head

    1983-01-01

    A survey in the Blue Mountains of north-eastern Oregon and southeastern Washington showed that, on the average, partial cuts in the grand fir/big huckleberry community were well stocked with a mixture of advance, natural post-harvest, and planted reproduction of a number of species. Partial cuts in the mixed conifer/pinegrass community had considerably fewer seedlings...

  7. Multi-millennial record of erosion and fires in the southern Blue Ridge Mountains, USA In: Greenberg, CH and BS Collins (eds.)

    Treesearch

    David S. Leigh

    2016-01-01

    Bottomland sediments from the southern Blue Ridge Mountains provide a coarse-resolution, multi-millennial stratigraphic record of past regional forest disturbance (soil erosion). This record is represented by 12 separate vertical accretion stratigraphic profi les that have been dated by radiocarbon, luminescence, cesium-137, and correlation methods...

  8. Coarse-scale population structure of pathogenic Armillaria species in a mixed-conifer forest in the Blue Mountains of northeast Oregon.

    Treesearch

    B.A. Ferguson; T.A. Dreisbach; C.G. Parks; G.M. Filip; C.L. Schmitt

    2003-01-01

    The coarse-scale population structure of pathogenic Armillaria (Fr.) Staude species was determined on approximately 16 100 ha Of relatively dry, mixed-conifer forest in the Blue Mountains of northeast Oregon. Sampling of recently dead or live, symptomatic conifers produced 112 isolates of Armillaria from six tree species.

  9. Historical patterns of western spruce budworm and Douglas-fir tussock moth outbreaks in the northern Blue Mountains, Oregon, since A.D. 1700.

    Treesearch

    Thomas Swetnam; Boyd E. Wickman; H. Gene Paul; Christopher H. Baisan

    1995-01-01

    Dendroecology methods were used to reconstruct a three-century history of western spruce budworm and Douglas-fir tussock moth outbreaks in the Blue Mountains of northeastern Oregon. Comparisons of 20th century Forest Service documentary records and host and nonhost tree-ring width chronologies provided an objective basis for distinguishing climatic effects from insect-...

  10. Comparative water quality of lightly- and moderately-impacted streams in the southern Blue Ridge Mountains, USA.

    PubMed

    Price, Katie; Leigh, David S

    2006-09-01

    For less-developed regions like the Blue Ridge Mountains, data are limited that link basin-scale land use with stream quality. Two pairs of lightly-impacted (90-100% forested) and moderately-impacted (70-80% forested) sub-basins of the upper Little Tennessee River basin in the southern Blue Ridge were identified for comparison. The pairs contain physically similar stream reaches, chosen for the purpose of isolating forest conversion as a potential driver of any detected differences in water quality. Streams were sampled during baseflow conditions twice monthly over a six-month period from September 2003 through February 2004. Parametric t-tests were run for each parameter measured between the lightly-and moderately-impacted streams within each pair. Statistically significantly higher mean values of suspended and dissolved solids, nitrate, specific conductivity, turbidity, and temperature were observed in the moderately impacted streams versus the lightly impacted streams in both pairs, while dissolved oxygen levels were lower in the moderately-impacted streams. No significant differences were demonstrated in orthophosphate or ammonium concentration. A near-bankfull runoff event on February 6, 2004, was sampled for stormflow values, and the results support baseflow findings. The water quality of these streams is very good when compared with lower relief areas like the Piedmont, and none of the parameters measured in this study exceeds levels of known threat to stream biota. However, the demonstration that moderate reductions in forest cover are associated with stream water quality degradation carries important implications for stream management in this rapidly developing mountainous region.

  11. Physical-Property Measurements on Core samples from Drill-Holes DB-1 and DB-2, Blue Mountain Geothermal Prospect, North-Central Nevada

    USGS Publications Warehouse

    Ponce, David A.; Watt, Janet T.; Casteel, John; Logsdon, Grant

    2009-01-01

    From May to June 2008, the U.S. Geological Survey (USGS) collected and measured physical properties on 36 core samples from drill-hole Deep Blue No. 1 (DB-1) and 46 samples from drill-hole Deep Blue No. 2 (DB-2) along the west side of Blue Mountain about 40 km west of Winnemucca, Nev. These data were collected as part of an effort to determine the geophysical setting of the Blue Mountain geothermal prospect as an aid to understanding the geologic framework of geothermal systems throughout the Great Basin. The physical properties of these rocks and other rock types in the area create a distinguishable pattern of gravity and magnetic anomalies that can be used to infer their subsurface geologic structure. Drill-holes DB-1 and DB-2 were spudded in alluvium on the western flank of Blue Mountain in 2002 and 2004, respectively, and are about 1 km apart. Drill-hole DB-1 is at a ground elevation of 1,325 m and was drilled to a depth of 672 m and drill-hole DB-2 is at a ground elevation of 1,392 m and was drilled to a depth of 1522 m. Diameter of the core samples is 6.4 cm. These drill holes penetrate Jurassic and Triassic metasedimentary rocks predominantly consisting of argillite, mudstone, and sandstone; Tertiary diorite and gabbro; and younger Tertiary felsic dikes.

  12. Comparison of vitrectomy with brilliant blue G or indocyanine green on retinal microstructure and function of eyes with macular hole.

    PubMed

    Baba, Takayuki; Hagiwara, Akira; Sato, Eiju; Arai, Miyuki; Oshitari, Toshiyuki; Yamamoto, Shuichi

    2012-12-01

    To evaluate the microstructure of the inner and outer retina and the visual function after macular hole (MH) surgery using brilliant blue G (BBG) or indocyanine green (ICG) to make the internal limiting membrane (ILM) more visible. Comparative, retrospective, interventional case series. Sixty-three eyes of 63 consecutive cases with MH were studied. Thirty-five eyes of 35 cases were treated with BBG between January and August 2011. Twenty-eight eyes of 28 MH cases were treated with ICG from April 2009 through April 2010. Vitrectomy was performed with a 23-gauge system and 0.25 mg/ml BBG or with 0.125% ICG. The best-corrected visual acuity (BCVA) and the microperimetry-determined retinal sensitivity were measured at baseline and at 3 and 6 months after surgery. The length of the defect of the photoreceptor inner segment/outer segment (IS/OS) junction and external limiting membrane (ELM), the central foveal thickness (CFT), and the thickness of the ganglion cell complex (GCC) were measured in the spectral-domain optical coherence tomographic images. The average BCVA was significantly better in the BBG group than in the ICG group at 3 months (P = 0.021) and 6 months (P = 0.045) after surgery. The mean retinal sensitivity in the BBG group was improved significantly in the central 2° at 3 and 6 months (P = 0.001 and P = 0.030, respectively), but was not significantly improved in the adjacent 10°. The length of IS/OS junction defect was significantly shorter in the BBG group at 3 months (P = 0.048), but was not significantly different at 6 months (P = 0.135). The length of ELM defect and the GCC thickness were not significantly different between the 2 groups at 3 and 6 months. The CFT was significantly thinner in the ICG group than in the BBG group at 3 and 6 months (P = 0.013 and P = 0.001, respectively). The postoperative BCVA and retinal sensitivity in the central 2° were better in eyes after BBG-assisted vitrectomy. The restoration of IS/OS junction was faster in

  13. High-power handheld blue laser-induced maculopathy: the results of the King Khaled Eye Specialist Hospital Collaborative Retina Study Group.

    PubMed

    Alsulaiman, Sulaiman M; Alrushood, Abdulaziz Adel; Almasaud, Jluwi; Alzaaidi, Sultan; Alzahrani, Yahya; Arevalo, J Fernando; Ghazi, Nicola G; Abboud, Emad B; Nowilaty, Sawsan R; Al-Amry, Mohammad; Al-Rashaed, Saba

    2014-02-01

    To report various types of maculopathy caused by momentary exposure to a high-power handheld blue laser. Consecutive case series. Fourteen eyes of 14 patients. Patients with a history of eye exposure to a blue laser device (450 nm and a power range of 150-1200 mW) to a single institution were included. Evaluation included a full ophthalmic examination, fundus photography, macular spectral-domain optical coherence tomography, and fundus fluorescein angiography. Analysis of the types of maculopathy and vitreoretinal pathologic features. All patients were young males. The most common setting for injury was accidental at play. The types of maculopathies encountered were: a full-thickness macular hole (FTMH) in 4 eyes, a premacular subhyaloid hemorrhage in 5 eyes, premacular sub-internal limiting membrane hemorrhage in 2 eyes, an outer retinal disruption at the fovea in 1 eye, an epimacular membrane in 1 eye, and a schisis-like cavity in 1 eye. Best-corrected Snellen visual acuity at presentation ranged from 20/40 to 4/200 (mean, 20/290). Only 4 eyes (29%) improved spontaneously with increase in vision, whereas 10 eyes (71%) required intervention. The latter consisted of neodymium:yttrium-aluminum-garnet hyaloidotomy in the 5 eyes with subhyaloid hemorrhage and pars plana vitrectomy (PPV) for the eyes with FTMH and epimacular membrane. All 4 FTMH were closed successfully after PPV. Final mean best-corrected visual acuity in all cases was 20/35 (range, 20/15-20/300). Exposure to high-power handheld laser devices can cause a variety of maculopathies that can reduce central vision permanently. Although vision may improve spontaneously, most cases require intervention. Unrestricted access to commercially available high-power handheld laser devices is dangerous and public awareness should be encouraged. Copyright © 2014 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  14. Evaluation of the cumulative (repeated application) eye irritation and corneal staining potential of FD&C yellow no. 5, FD&C blue no. 1 and FD&C blue no. 1 aluminium lake.

    PubMed

    Gettings, S D; Blaszcak, D L; Roddy, M T; Curry, A S; McEwen, G N

    1992-12-01

    A protocol to evaluate the ocular irritation, staining, and embedding potential of FD&C colours (Yellow No. 5, Blue No. 1, Blue No. 1 Aluminium Lake) produced by repeated topical application to rabbit eyes is described. Test materials (3%, w/v in aqueous vehicle) were administered once daily, for a total of 21 days, to the conjunctival sac of the right eye of New Zealand White Rabbits (6 of each sex per group) at a dose volume of 30 microliters. Control animals (6 of each sex) received 30 microliters of the vehicle daily. All animals survived and were free of significant clinical signs of toxicity throughout the study. Ophthalmoscopic examinations revealed that all animals were free of abnormalities considered to be of clinical importance; all animals were free of significant signs of ocular irritation, staining and particle embedment. The results of this study support the safe use of these materials in consumer products intended for use in the eye area.

  15. Blue-light-receptive cryptochrome is expressed in a sponge eye lacking neurons and opsin.

    PubMed

    Rivera, Ajna S; Ozturk, Nuri; Fahey, Bryony; Plachetzki, David C; Degnan, Bernard M; Sancar, Aziz; Oakley, Todd H

    2012-04-15

    Many larval sponges possess pigment ring eyes that apparently mediate phototactic swimming. Yet sponges are not known to possess nervous systems or opsin genes, so the unknown molecular components of sponge phototaxis must differ fundamentally from those in other animals, inspiring questions about how this sensory system functions. Here we present molecular and biochemical data on cryptochrome, a candidate gene for functional involvement in sponge pigment ring eyes. We report that Amphimedon queenslandica, a demosponge, possesses two cryptochrome/photolyase genes, Aq-Cry1 and Aq-Cry2. The mRNA of one gene (Aq-Cry2) is expressed in situ at the pigment ring eye. Additionally, we report that Aq-Cry2 lacks photolyase activity and contains a flavin-based co-factor that is responsive to wavelengths of light that also mediate larval photic behavior. These results suggest that Aq-Cry2 may act in the aneural, opsin-less phototaxic behavior of a sponge.

  16. Don't it make my brown eyes blue: co-witness misinformation about a target's appearance can impair target-absent line-up performance.

    PubMed

    Zajac, Rachel; Henderson, Nicola

    2009-04-01

    Misinformation from another witness has been shown to impair eyewitness reports, but little is known about how it may influence eyewitness identification. In Experiment 1, adult pairs comprising one participant and one experimental confederate viewed a video clip of a staged theft. Half of the participants were then misinformed by the confederate that the thief's accomplice had blue eyes (in fact, they were brown). Next, individual participants described the accomplice and completed a target-absent photographic line-up task comprising blue-eyed members. Misinformed participants were several times more likely than controls to describe the accomplice as having blue eyes, and twice as likely to identify someone from the line-up. In Experiment 2, when line-up members' eye colour was digitally altered from blue to brown, the line-up effect disappeared, suggesting that the increase in identifications in Experiment 1 was not a generalised increase in willingness to choose from the line-up. In Experiment 3, we discounted the possibility that discussion alone could account for the line-up misinformation effect, by subjecting all participants to co-witness discussion.

  17. Development of a Bird Integrity Index: measuring avian response to disturbance in the Blue Mountains of Oregon, USA.

    PubMed

    Bryce, Sandra A

    2006-09-01

    The Bird Integrity Index (BII) presented here uses bird assemblage information to assess human impacts to 28 stream reaches in the Blue Mountains of eastern Oregon. Eighty-one candidate metrics were extracted from bird survey data for testing. The metrics represented aspects of bird taxonomic richness, tolerance or intolerance to human disturbance, dietary preferences, foraging techniques, and nesting strategies that were expected to be positively or negatively affected by human activities in the region. To evaluate the responsiveness of each metric, it was plotted against an index of reach and watershed disturbance that included attributes of land use/land cover, road density, riparian cover, mining impacts, and percent area in clearcut and partial-cut logging. Nine of the 81 candidate bird metrics remained after eliminating unresponsive and highly correlated metrics. Individual metric scores ranged from 0 to 10, and BII scores varied between 0 and 100. BII scores varied from 78.6 for a minimally disturbed, reference stream reach to 30.4 for the most highly disturbed stream reach. The BII responded clearly to varying riparian conditions and to the cumulative effects of disturbances, such as logging, grazing, and mining, which are common in the mountains of eastern Oregon. This BII for eastern Oregon was compared to an earlier BII developed for the agricultural and urban disturbance regime of the Willamette Valley in western Oregon. The BII presented here was sensitive enough to distinguish differences in condition among stream riparian zones with disturbances that were not as obvious or irreversible as those in the agricultural/urban conditions of western Oregon.

  18. Forest health in the Blue Mountains: A plant ecologist`s perspective on ecosystem processes and biological diversity. Forest Service general technical report

    SciTech Connect

    Johnson, C.G.

    1994-09-01

    Natural disturbances are important to ecosystem processes. Disturbances historically have occurred in the vegetation of the Blue Mountain area of northeastern Oregon and southeastern Washington. The primary modifying events that historically have cycled through most of its plant communities are fire, grazing and browsing, insect and disease epidemics, windthrow, flooding, and erosion. Knowledge of plant successional pathways enables managers to predict the probable course of community development for a disturbance regime. Recommendations for restoring the Blue Mountains area are to reintroduce fire into the ecosystem, restore rangeland, and enhance biological diversity by practicing landscpe ecological management and by emulating natural patterns on the landscape. Periodic and timely sampling after these activities is critical to assessing the results by adaptive management needs.

  19. Multilocus species identification and fungal DNA barcoding: insights from blue stain fungal symbionts of the mountain pine beetle.

    PubMed

    Roe, Amanda D; Rice, Adrianne V; Bromilow, Sean E; Cooke, Janice E K; Sperling, Felix A H

    2010-11-01

    There is strong community-wide interest in applying molecular techniques to fungal species delimitation and identification, but selection of a standardized region or regions of the genome has not been finalized. A single marker, the ribosomal DNA internal transcribed spacer region, has frequently been suggested as the standard for fungi. We used a group of closely related blue stain fungi associated with the mountain pine beetle (Dendroctonus ponderosae Hopkins) to examine the success of such single-locus species identification, comparing the internal transcribed spacer with four other nuclear markers. We demonstrate that single loci varied in their utility for identifying the six fungal species examined, while use of multiple loci was consistently successful. In a literature survey of 21 similar studies, individual loci were also highly variable in their ability to provide consistent species identifications and were less successful than multilocus diagnostics. Accurate species identification is the essence of any molecular diagnostic system, and this consideration should be central to locus selection. Moreover, our study and the literature survey demonstrate the value of using closely related species as the proving ground for developing a molecular identification system. We advocate use of a multilocus barcode approach that is similar to the practice employed by the plant barcode community, rather than reliance on a single locus. © 2010 Blackwell Publishing Ltd.

  20. Prehistoric Versus Historic Floodplain Sedimentation Rates in the Upper Little Tennessee River Valley, Blue Ridge Mountains, North Carolina, USA

    NASA Astrophysics Data System (ADS)

    Leigh, D. S.

    2008-12-01

    Late prehistoric and historic floodplain sedimentation rates were examined along the Upper Little Tennessee River within a 363 km2 catchment of the Southern Blue Ridge Mountains in western North Carolina. Sedimentation rates were derived from stratigraphy, sedimentology, radiocarbon and cesium-137 dates at three mainstem floodplain sample sites using cores and outcrops. Particle size was measured in continuous down-column overbank sediment samples (1-3 cm increments) to document individual floods as time markers. Results indicate that late prehistoric sedimentation rates were less than 1 mm/yr, whereas historical sedimentation rates are about an order of magnitude higher (5 to 17 mm/yr). The historical floodplain has accreted up to two meters higher than prehistoric levels, while the channel bed remains approximately at prehistoric levels. The most rapid historical sedimentation rates of 13-17 mm/yr occurred between 1963 and 2004, corresponding to a time period of second home construction, road construction, and other erosive land uses related to population and infrastructure growth; whereas pre-1963 historical sedimentation rates correspond to former timber harvest and agricultural activities. The most recent phase from1963 to present also corresponds to a time of relatively rapid lateral migration, incipient floodplain formation, and natural levee progradation on historically terraced cutbanks. Ongoing research relates channel morphogenesis, bank erosion, and remobilization of historical sediment to the overall sediment budget.

  1. Metamorphosed oceanic lithosphere from the Chunky Gal Mountain complex, Blue Ridge province, North Carolina

    SciTech Connect

    Ranson, W.A.; Garihan, J.M. . Dept. of Geology)

    1993-03-01

    Closely associated dunite and layered troctolite, gabbro, and anorthosite from the Chunky Gal Mountain mafic-ultramafic complex suggest a related ocean floor origin for these lithologies, with regional emplacement by the pre-metamorphic Hayesville-Fries thrust of Taconic age. Anhydrous mineral assemblages of dunitic and troctolitic rocks were more resistant to granulite and upper amphibolite metamorphic episodes, retaining much of their original mineralogy. Dunite consists of fresh polycrystalline olivine with local development of anthophyllite, serpentine, and talc along fractures. Dunite adjacent to mafic amphibolites of the complex contains distinctive cm-scale bands or layers of recrystallized plagioclase( ) of uncertain affinity, possibly veins or rhythmic layers. Troctolitic rocks display reaction textures around fresh olivine and plagioclase. Orthopyroxene growing normal to olivine grain boundaries forms an inner corona, in turn surrounded by a complex symplectite of Cpx + Plag [+-] Grt [+-] Spl. Gabbroic rocks show nearly complete replacement of original mafic minerals. Orthopyroxene survives in a few gabbros but mostly has been replaced by emerald green alumino-magnesio-hornblende. Calcic plagioclase is abundant as subhedral crystals or as oval, polycrystalline clots and pink corundum constitutes an accessory phase. A possible reaction resulting in the observed aluminous assemblage is: Na-Plag + Opx + Di + Spl + fluid = Mg-Hbl + Crn + Ca-Plag. Anorthosites occur as layers 10--50 cm in width within layered troctolites and consist of beautifully recrystallized plagioclase with seriate texture and minor amounts of alumino-magnesio hornblende occurring as fine-grained clots. Contacts between anorthosite and troctolite display the same sort of symplectite formed as an outer corona around olivine in the troctolite.

  2. A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color.

    PubMed

    Sturm, Richard A; Duffy, David L; Zhao, Zhen Zhen; Leite, Fabio P N; Stark, Mitchell S; Hayward, Nicholas K; Martin, Nicholas G; Montgomery, Grant W

    2008-02-01

    We have previously demonstrated that haplotypes of three single nucleotide polymorphisms (SNPs) within the first intron of the OCA2 gene are extremely strongly associated with variation in human eye color. In the present work, we describe additional fine association mapping of eye color SNPs in the intergenic region upstream of OCA2 and within the neighboring HERC2 (hect domain and RLD2) gene. We screened an additional 92 SNPs in 300-3000 European individuals and found that a single SNP in intron 86 of HERC2, rs12913832, predicted eye color significantly better (ordinal logistic regression R(2) = 0.68, association LOD = 444) than our previous best OCA2 haplotype. Comparison of sequence alignments of multiple species showed that this SNP lies in the center of a short highly conserved sequence and that the blue-eye-associated allele (frequency 78%) breaks up this conserved sequence, part of which forms a consensus binding site for the helicase-like transcription factor (HLTF). We were also able to demonstrate the OCA2 R419Q, rs1800407, coding SNP acts as a penetrance modifier of this new HERC2 SNP for eye color, and somewhat independently, of melanoma risk. We conclude that the conserved region around rs12913832 represents a regulatory region controlling constitutive expression of OCA2 and that the C allele at rs12913832 leads to decreased expression of OCA2, particularly within iris melanocytes, which we postulate to be the ultimate cause of blue eye color.

  3. Concentrating Antarctic Meteorites on Blue ice Fields: The Frontier Mountain Meteorite Trap

    NASA Technical Reports Server (NTRS)

    Sandford, Scott A.; DeVincenzi, D. (Technical Monitor)

    2002-01-01

    The collection of meteorites in Antarctica has greatly stimulated advancement in the field of meteoritics by providing the community with significant numbers of rare and unique meteorites types and by yielding large numbers of meteorites that sample older infall epochs (Grady et al., 1998). The majority of Antarctic meteorites are found on blue ice fields, where they are thought to be concentrated by wind and glacial drift (cf. Cassidy et al., 1992). The basic "ice flow model" describes the concentration of meteorites by the stagnation or slowing of ice as it moves against a barrier located in a zone with low snow accumulation. However, our limited knowledge of the details of the actual concentration mechanisms prevents establishing firm conclusions concerning the past meteorite flux from the Antarctic record (Zolensky, 1998). The terrestrial ages of Antarctic meteorites indicate that their concentration occurs on time scales of tens to hundreds of thousands of years (Nishiizumi et al., 1989). It is a challenge to measure a mechanism that operates so slowly, and since such time scales can span more than one glacial epoch one cannot assume that the snow accumulation rates, ice velocities and directions, etc. that are measured today are representative of those extant over the age of the trap. Testing the basic "ice flow model" therefore requires the careful measurement of meteorite locations, glacialogical ice flow data, ice thicknesses, bedrock and surface topology, ice ablation and snow accumulation rates, and mass transport by wind over an extended period of time in a location where these quantities can be interpreted in the context of past glacialogical history.

  4. Devitrification of the Carlton Rhyolite in the Blue Creek Canyon area, Wichita Mountains, southwestern Oklahoma

    SciTech Connect

    Bigger, S.E. . Dept. of Geology); Hanson, R.E. . Dept. of Geology)

    1993-02-01

    The Cambrian Carlton Rhyolite is a sequence of lava flows and ignimbrites extruded in association with rifting in the Southern Oklahoma aulacogen. Rhyolite exposed in the Blue Creek Canyon area consists of a single, originally glassy, porphyritic lava flow > 300 m thick. Abundant flow banding is deformed by variably oriented flow folds present on both outcrop and thin-section scales. A variety of complex texture record the cooling, degassing, and devitrification history of the flow. Acicular Fe, Ti-oxide crystallites aligned in the flow banding document nucleation and limited crystal growth during flow. Spherical microvesicles and larger lithophysal cavities up to 10 cm long crosscut flow banding, showing that degassing continued after flow had ceased. Pseudomorphs of quartz after cristobalite and tridymite are present on cavity walls and are products of high-T vapor-phase crystallization. Devitrification textures overprint the flow banding and developed in two stages. Primary devitrification occurred during initial cooling and formed spherulitic intergrowths in distinct areas bound by sharp devitrification fronts. Spherulites nucleated on phenocrysts, vesicles, and flow bands and show evidence of multiple episodes of growth. Rhyolite outside of the devitrification fronts initially remained glassy but underwent later, low-T hydration to form perlitic texture, which was followed by prolonged secondary devitrification to form extremely fine-grained, equigranular quartzofeldspathic mosaics. Snowflake texture (micropoikilitic quartz surrounding randomly oriented alkali feldspar) developed during both primary and secondary devitrification. Spherical bodies up to 30 cm across are present in discrete horizons within the flow and weather out preferentially from the host rhyolite.

  5. Effect of Blue Light-Reducing Eye Glasses on Critical Flicker Frequency.

    PubMed

    Ide, Takeshi; Toda, Ikuko; Miki, Emiko; Tsubota, Kazuo

    2015-01-01

    This study aims to evaluate the effect of blocking short-wavelength light on critical flicker frequency (CFF). This study is a prospective clinical study. Thirty-three participants (17 men and 16 women; age range, 28-39 years) were divided into 3 groups. Each group wore 1 of 3 types of lenses while performing an intensive computer task for 2 hours. To evaluate the effect of blocking short-wavelength light before and after the task, we measured the CFF and evaluated subjective questionnaires. We used the analysis of variance test to examine whether the type of lenses tested affected any of the visual fatigue-related parameters. The type of lens worn significantly affected the CFF; however, answers to the subjective questionnaires did not differ significantly between the groups. Two of the 13 question items showed a statistical difference between lens transparency and increase in the CFF (lens 3 > lens 2 > lens 1). The higher the blocking effect of the lens, the lower the reduction in the CFF, suggesting that blocking short-wavelength light can reduce eye fatigue.

  6. Petrogenesis of Garnet-bearing Rocks in the Grandfather Mountain Window, Blue Ridge Province, Western North Carolina

    NASA Astrophysics Data System (ADS)

    Frushour, A. M.; Abbott, R. N.

    2014-12-01

    The Grandfather Mountain Window in western North Carolina exposes the lowest structural level in the Blue Ridge Province. Rocks in the window constitute a Late Proterozoic basement-cover sequence. The basement consists mainly of Blowing Rock Gneiss (sic, porphyroblastic schist) and Wilson Creek Gneiss, both overlain unconformably by the Grandfather Mountain Formation. All of these rocks have been pervasively overprinted by greenschist facies metamorphism. The typical greenschist mineral assemblage involves combinations of chlorite, muscovite, biotite, actinolite, epidote, calcite, quartz, albite and K-feldspar. Garnet discovered in basement rock calls into question the metamorphic grade. The average garnet (core-rim) is (Fe1.63-1.71Mn0.64-0.77Ca0.52-0.37Mg0.10-0.12)Al1.98-1.96Si3.06-3.04O12; the average biotite is (K0.96Na0.06Ca0.02)(Fe1.73Mg0.87Mn0.02Ti0.04Al0.23)(Si2.83Al1.17)O10(OH)2; the average muscovite is (K1.03Na0.02Ca0.02)(Al1.57Fe0.26Mg0.16Ti0.01)(Si3.31Al0.69)O10(OH)2. Thermometry involving Fe-Mn-Mg components in these minerals gives 766°C (+/- 91°C) at 13.6 kbars (+/- 1.4 kbar), respectively. There are at least four explanations for garnet in these rocks: (1) Garnet may have been stabilized in the greenschist facies by non-AFM components (esp. Mn), but the compositions are not unusual for metamorphic garnet, biotite and muscovite, and the calculated temperatures are too high for greenschist facies. (2) The garnet may be relict from earlier contact metamorphism, but the garnet is not spatially related to otherwise common metamorphosed (greenschist facies) mafic dikes. (3) The garnet is a product of heating during mylonitization. Finally, and most likely, (4) the garnet may be relict from an earlier episode of regional metamorphism. Samples of porphyroblastic schist and greenstone from the same outcrop give low temperature, greenschist facies conditions.

  7. The generation of high Sr/Y plutons following Late Jurassic arc-arc collision, Blue Mountains province, NE Oregon

    NASA Astrophysics Data System (ADS)

    Schwartz, Joshua J.; Johnson, Kenneth; Miranda, Elena A.; Wooden, Joseph L.

    2011-09-01

    High Sr/Y plutons (Sr/Y > 40) occupy large areas in ancient and modern orogenic belts, yet considerable controversy exists regarding mechanisms of their generation, the tectonic settings in which they form, and their relationship to contractional deformation through time. In the Blue Mountains province (NE Oregon), a suite of Late Jurassic (148-145 Ma), high Sr/Y plutons intrude Middle Jurassic (162-157 Ma), low Sr/Y (< 40) arc-related lavas and plutons in the Dixie Butte area immediately after widespread Late Jurassic arc-arc collision (159-154 Ma). Early, pre- to syn-kinematic low Sr/Y lavas and plutons (162-157 Ma) have flat to slightly enriched light rare earth element (REE) abundances, low Sr (< 400 ppm) and Sr/Y values (< 40), and strongly positive initial epsilon Hf values (+ 10.1 to + 12.3: 2σ weighted average). Ce/Y values from basalts and gabbros yield a maximum crustal thickness of ~ 23 km. These geochemical and isotopic features suggest derivation from a depleted-mantle source and/or shallow-level (≪ 40 km) melting of pre-existing island arc crust with little to no evolved crustal input. In contrast, post-kinematic high Sr/Y plutons (148-145 Ma) are more compositionally restricted (tonalite-trondhjemite-granodiorite) and display depleted heavy REE abundances, an absence of Eu anomalies, elevated Sr (> 600 ppm) and Sr/Y values (> 40), and positive initial epsilon Hf values (+ 10.5 to + 7.8: 2σ weighted average). These geochemical and isotopic results are consistent with geochemical models suggesting derivation from partial melting of island arc crust in the presence of a plagioclase-poor to absent, clinopyroxene + hornblende + garnet-bearing source (depths > 35-40 km). We propose that the transition from low Sr/Y to high Sr/Y magmatism resulted from orogenic thickening of island arc crust in the Dixie Butte area during Late Jurassic arc-arc collision between the Olds Ferry and Wallowa island arcs at 159-154 Ma. This fundamental change in crustal

  8. Miocene slip history of the Eagle Eye detachment fault, Harquahala Mountains metamorphic core complex, west-central Arizona

    NASA Astrophysics Data System (ADS)

    Prior, Michael G.; Stockli, Daniel F.; Singleton, John S.

    2016-08-01

    The structural and thermal evolution of major low-angle normal faults in the Colorado River extensional corridor has been a controversial topic since the pioneering studies of metamorphic core complexes in the early 1980s. We present new geo-thermochronometry data from the Harquahala Mountains in west-central Arizona to determine the timing of extension, displacement magnitude, and slip rates along the Eagle Eye detachment fault (EED) during large-magnitude Miocene extension. Zircon and apatite (U-Th)/He data (ZHe and AHe, respectively) from 31 samples along a 55 km extension-parallel transect indicate active slip along the EED occurred between 21 ± 1 Ma and 14 Ma. The spatial extent of ZHe ages and exhumation of the zircon partial retention zone indicated 44 ± 2 km of total displacement, whereas lithologic similarity and identical U-Pb ages between correlated footwall rocks in the Little Harquahala Mountains and breccia clasts at Bullard Peak in the NE Harcuvar Mountains indicated 43-45 km of displacement across the EED. AHe and ZHe data indicated slip rates of 6.7 + 7.8/-2.3 km/Myr, and 6.6 + 7.1/-2.0 km/Myr, respectively, both consistent with the duration and displacement estimates. The EED initiated as a listric fault with an 34 ± 9° dip that decreased to 13 ± 5° below 7 km depth. Secondary breakaway development and footwall exposure occurred by 17 Ma, during active EED slip. Lithologic and geo-thermochronometric offset constraints show excellent agreement and provided a rare opportunity to fully resolve the timing, rates, and total displacement magnitudes along a major continental detachment fault.

  9. Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity

    PubMed Central

    Kaido, Minako

    2016-01-01

    Purpose To investigate whether suppression of blue light can improve visual function in patients with short tear break up time (BUT) dry eye (DE). Methods Twenty-two patients with short BUT DE (10 men, 12 women; mean age, 32.4 ± 6.4 years; age range, 23–43 years) and 18 healthy controls (10 men, 8 women; mean age, 30.1 ± 7.4 years; age range, 20–49 years) underwent functional visual acuity (VA) examinations with and without wearing eyeglasses with 50% blue light blocked lenses. The functional VA parameters were starting VA, functional VA, and visual maintenance ratio. Results The baseline mean values (logarithm of the minimum angle of resolution, logMAR) of functional VA and the visual maintenance ratio were significantly worse in the DE patients than in the controls (P < 0.05), while no significant difference was observed in the baseline starting VA (P > 0.05). The DE patients had significant improvement in mean functional VA and visual maintenance ratio while wearing the glasses (P < 0.05), while there were no significant changes with and without the glasses in the control group (P > 0.05), Conclusions Protecting the eyes from short-wavelength blue light may help to ameliorate visual impairment associated with tear instability in patients with DE. This finding represents a new concept, which is that the blue light exposure might be harmful to visual function in patients with short BUT DE. PMID:27045760

  10. Visual sensitivity in the crepuscular owl butterfly Caligo memnon and the diurnal blue morpho Morpho peleides: a clue to explain the evolution of nocturnal apposition eyes?

    PubMed

    Frederiksen, Rikard; Warrant, Eric J

    2008-03-01

    Insects active in dim light, such as moths and many beetles, normally have superposition compound eyes to increase photon capture. But there are nocturnal and crepuscular insects - such as some species of bees, wasps and butterflies - that have apposition compound eyes. These are likely to have adaptations - including large eye and facet size and coarsened spatial and temporal resolution - that improve their sensitivity and thus their visual reliability. Is this also true for crepuscular insects that are active at intermediate intensities? To test this hypothesis, the visual performance of two closely related butterflies, the diurnal blue morpho Morpho peleides and the crepuscular owl butterfly Caligo memnon, were compared. Compared to the diurnal M. peleides, the crepuscular C. memnon does not appear to be adapted to a nocturnal lifestyle in terms of spatial resolution: the interommatidial angle Delta is similar in both species, and acceptance angles, Deltarho, are only marginally larger in C. memnon. Moreover, temporal resolution is only a little coarser in C. memnon compared to M. peleides. Using a model for sensitivity, we found that the eyes of C. memnon are about four times as light-sensitive as those of M. peleides in the frontal visual field, much of this difference being due to the larger facet diameters found in C. memnon. In summary, greater visual sensitivity has evolved in C. memnon than in M. peleides, showing that adaptations that improve sensitivity can be found not only in nocturnal apposition eyes, but also on a smaller scale in crepuscular apposition eyes.

  11. Groundwater residence times in Shenandoah National Park, Blue Ridge Mountains, Virginia, USA: A multi-tracer approach

    USGS Publications Warehouse

    Plummer, L.N.; Busenberg, E.; Böhlke, J.K.; Nelms, D.L.; Michel, R.L.; Schlosser, P.

    2001-01-01

    Chemical and isotopic properties of water discharging from springs and wells in Shenandoah National Park (SNP), near the crest of the Blue Ridge Mountains, VA, USA were monitored to obtain information on groundwater residence times. Investigated time scales included seasonal (wet season, April, 1996; dry season, August-September, 1997), monthly (March through September, 1999) and hourly (30-min interval recording of specific conductance and temperature, March, 1999 through February, 2000). Multiple environmental tracers, including tritium/helium-3 (3H/3He), chlorofluorocarbons (CFCs), sulfur hexafluoride (SF6), sulfur-35 (35S), and stable isotopes (??18O and ??2H) of water, were used to estimate the residence times of shallow groundwater discharging from 34 springs and 15 wells. The most reliable ages of water from springs appear to be based on SF6 and 3H/3He, with most ages in the range of 0-3 years. This range is consistent with apparent ages estimated from concentrations of CFCs; however, CFC-based ages have large uncertainties owing to the post-1995 leveling-off of the CFC atmospheric growth curves. Somewhat higher apparent ages are indicated by 35S (> 1.5 years) and seasonal variation of ??18O (mean residence time of 5 years) for spring discharge. The higher ages indicated by the 35S and ??18O data reflect travel times through the unsaturated zone and, in the case of 35S, possible sorption and exchange of S with soils or biomass. In springs sampled in April, 1996, apparent ages derived from the 3H/3He data (median age of 0.2 years) are lower than those obtained from SF6 (median age of 4.3 years), and in contrast to median ages from 3H/3He (0.3 years) and SF6 (0.7 years) obtained during the late summer dry season of 1997. Monthly samples from 1999 at four springs in SNP had SF6 apparent ages of only 1.2 to 2.5 ?? 0.8 years, and were consistent with the 1997 SF6 data. Water from springs has low excess air (0-1 cm3 kg-1) and N2-Ar temperatures that vary

  12. IrisPlex: a sensitive DNA tool for accurate prediction of blue and brown eye colour in the absence of ancestry information.

    PubMed

    Walsh, Susan; Liu, Fan; Ballantyne, Kaye N; van Oven, Mannis; Lao, Oscar; Kayser, Manfred

    2011-06-01

    A new era of 'DNA intelligence' is arriving in forensic biology, due to the impending ability to predict externally visible characteristics (EVCs) from biological material such as those found at crime scenes. EVC prediction from forensic samples, or from body parts, is expected to help concentrate police investigations towards finding unknown individuals, at times when conventional DNA profiling fails to provide informative leads. Here we present a robust and sensitive tool, termed IrisPlex, for the accurate prediction of blue and brown eye colour from DNA in future forensic applications. We used the six currently most eye colour-informative single nucleotide polymorphisms (SNPs) that previously revealed prevalence-adjusted prediction accuracies of over 90% for blue and brown eye colour in 6168 Dutch Europeans. The single multiplex assay, based on SNaPshot chemistry and capillary electrophoresis, both widely used in forensic laboratories, displays high levels of genotyping sensitivity with complete profiles generated from as little as 31pg of DNA, approximately six human diploid cell equivalents. We also present a prediction model to correctly classify an individual's eye colour, via probability estimation solely based on DNA data, and illustrate the accuracy of the developed prediction test on 40 individuals from various geographic origins. Moreover, we obtained insights into the worldwide allele distribution of these six SNPs using the HGDP-CEPH samples of 51 populations. Eye colour prediction analyses from HGDP-CEPH samples provide evidence that the test and model presented here perform reliably without prior ancestry information, although future worldwide genotype and phenotype data shall confirm this notion. As our IrisPlex eye colour prediction test is capable of immediate implementation in forensic casework, it represents one of the first steps forward in the creation of a fully individualised EVC prediction system for future use in forensic DNA intelligence.

  13. Woodland clearance alters geomorphic, hydrologic, and pedogenic drivers of ecosystem services: examples from the southern Blue Ridge (USA) and the French western Pyrenees Mountains

    NASA Astrophysics Data System (ADS)

    Leigh, David

    2016-04-01

    The southern Blue Ridge (USA) and French western Pyrenees both are humid-temperate mountains where native woodlands have been cleared on soils formed in residuum and colluvium on hillslopes. Forest removal increased rates of erosion and sediment yield that drove both negative and positive ecosystem services. For example, the supportive ecosystem service of soil formation was diminished on eroded hillslopes, but may have been enhanced by accumulation of sediment on bottomlands far downstream from the highland source areas. Negative effects on provisional ecosystem services (e.g. water supply) resulted in aggraded bottomlands by increasing the depth to the water table. Legacy effects linger on hillslopes that reforested (diminished soil properties), and ongoing alteration of pedogenic and hydrologic processes affect pastures that persisted from cleared woodlands. Beyond those general similarities, pastures of the two regions exhibit very different pedogenic pathways and ecosystem service outcomes. Soils of the Blue Ridge pastures adhere to a typical degradation scenario of erosion, compaction, and reduced infiltration capacities, whereas Pyrenees pastures exhibit soil qualities trending in the opposite direction and arguably now are better quality soils than their forested predecessors. Major differences in temporal duration and management styles apparently have led to such contrasts in soil quality. The Blue Ridge pastures are only tens to hundreds of years old, whereas Pyrenees pastures are thousands of years old. Blue Ridge pastures are maintained by mowing with tractors and year-round grazing primarily with beef cattle, whereas Pyrenees pastures (outfields) lack tractors and are only grazed seasonally (summer), primarily with sheep. Fire is rarely used as a management tool in the Blue Ridge, while Pyrenees pastures frequently are burned. Such management practices, and their influence on pedogenic and hydrologic processes, generally have resulted in negative

  14. Historical patterns of western spruce budworm and douglas-fir tussock moth outbreaks in the northern Blue Mountains, Oregon, since a.d. 1700. Forest Service research paper

    SciTech Connect

    Swetnam, T.W.; Wickman, B.E.; Paul, H.G.; Baisan, C.H.

    1995-10-01

    Tree-ring samples from 21 mixed-conifer stands in the Blue Mountains of northeastern Oregon were analyzed for evidence of past western spruce budworm and Douglas-fir tussock moth outbreaks. Comparison of host and nonhost tree-ring growth provided an objective basis for distinguishing climatic effects from insect defoliation effects. Our reconstruction shows that since ca. A.D. 1700 at least eight regional budworm outbreaks occurred at intervals of about 21 to 53 years. Reduced radial growth periods caused by defoliation lasted from 13 to 17 years. Two regional budworm out-breaks occurred in the 19th century (ca. 1806 to 1822 and ca. 1851 to 1867), three outbreaks occurred in the northern Blue Mountains in the 20th century (ca. 1898 to 1910, ca. 1946 to 1958, and ca. 1980 to present), and an additional outbreak occurred in the Eagle Cap Wilderness (ca. 1925 to 1939). These findings generally lend support to the hypothesis that budworm outbreaks have increased in frequency and severity in the 20th century in northeastern Oregon.

  15. National Dam Inspection Program. Blue Mountain Lake Dam (NDI ID PA 00627, PA DER 45-34), Delaware River Basin, Unnamed Tributary of Brodhead Creek, Pennsylvania. Phase I Inspection Report

    DTIC Science & Technology

    1981-08-01

    mounood [ ,3Q,,s’t,lt l oo &I on .. .. .+ MCCR DELAWARE RIVER BASIN Avallability Co4e _Avail- and/tim’eor - 11As pecial8J BLUE MOUNTAIN LAKE DAM...concrete reservoir outlet pipe discharges into the spillway channel about 50 feet downstream of the embankment. The inlet gate, which is located in the...impoundment at the upstream end of the pipe , is no longer operable. b. Lncation. Blue Mountain Lake Dam is located on a branch of Ruliffs Run, about 2.5

  16. Exploring Elongation-Inclination Relationships in Datasets from Plutons and Remagnetized Sediments: Examples from the North Cascades and the Blue Mountains

    NASA Astrophysics Data System (ADS)

    Housen, B. A.

    2014-12-01

    Tectonic applications of paleomagnetism rely upon establishment of paleohorizontal at the time of magnetization. Paleohorizontal can be established in sedimentary rocks and volcanics, but is poorly constrained in plutonic rocks and areas that have experienced regional remagnetizations. This study will explore another latitudinal-dependent property of the geomagnetic field- elongation of elliptical distributions of directional data- to evaluate whether the combination of elongation and inclination can be used to constrain effects of tilt or other paleohorizontal uncertainties in paleomagnetic datasets. This work is inspired by the application of the E-I relationship proposed by Tauxe and Kent (2004) to evaluate effects of inclination error in sedimentary rocks. The first example is from the Blue Mountains of eastern OR. Remagnetized Permian-Jurassic sedimentary rocks (Hillhouse et al, 1982, Harbert et al, 1995, Housen, 2007, Kalk, 2008) have magnetizations that match those of Late Jurassic-Early Cretaceous plutons (Wilson and Cox, 1980, Housen, 2007). Directions from 64 sites of these rocks yields a mean of D = 33°, I = 64°, k= 26, α95 = 3.7°. The E-I method can be used to determine the effects of calculated paleohorizontal errors by finding an optimal paleohorizontal error that results in the best agreement between E and I for a set of data. For the Blue Mountains rocks, the optimal E-I relationship yields a corrected inclination of I = 65° (+7°/-4°), and estimated paleolatitude of 47°N (42° to 57°). The second example is from the Cretaceous Mt Stuart batholith in the North Cascades of central WA- these 95-88 Ma plutonic rocks have well defined magnetizations (Housen et al, 2003). Directions from 89 samples have a mean of D = 350°, I=44°, k=50, α95 = 2.1°. The E-I relationship suggests a corrected mean inclination of I=46° (+12°/-3°), and estimated paleolatitude of 27°N (25° to 39°). For the Blue Mountains, this comparison indicates that the

  17. Growth and mortality of ponderosa pine poles thinned to various densities in the Blue Mountains of Oregon.

    Treesearch

    P.H. Cochran; James W. Barrett

    1995-01-01

    Growth and mortality in a ponderosa pine (Pinus ponderosa Dougl. ex Laws.) stand were investigated for 24 years. High mortality rates from mountain pine beetle (Dendroctonus ponderosae Hopkins) occurred on some plots where values for stand density index exceeded 140. Periodic annual increments for quadratic mean diameters...

  18. Forest health in the Blue Mountains: Science perspectives. A management strategy for fire-adapted ecosystems. Forest Service general technical report

    SciTech Connect

    Mutch, R.W.; Arno, S.F.; Brown, J.K.; Carlson, C.E.; Ottmar, R.D.

    1993-02-01

    The fire-adapted forests of the Blue Mountains are suffering from a forest health problem of catastrophic proportions. The composition of the forest at lower elevations has shifted from historically open-growth stands of primarily ponderosa pine and western larch to stands with dense understories of Douglas-fir and grand fir. Epidemic levels of insect infestations and large wildfires adversely affect visual quality, wildlife habitat, stream sedimentation, and timber values. A management strategy to restore forest health at lower elevations will require that the seral ponderosa pine and western larch stands be managed for much lower tree densities and a more open coniferous understory. A combination of silvicultural partial cutting and prescribed fire on a large scale will be needed to produce the desired future condition of healthy, open, and park-like forests.

  19. Crustal thickness variations across the Blue Ridge mountains, southern Appalachians: an alternative procedure for migrating wide-angle reflection data

    Treesearch

    Robert B. Hawman

    2008-01-01

    Migration of wide-angle reflections generated by quarry blasts suggests that crustal thickness increases from 38 km beneath the Carolina Terrane to 47–51 km along the southeastern flank of the Blue Ridge. The migration algorithm, developed for generating single-fold images from explosions and earthquakes recorded with isolated, short-aperture arrays, uses the localized...

  20. Early Mesozoic paleogeography and tectonic evolution of the western United States: Insights from detrital zircon U-Pb geochronology, Blue Mountains Province, northeastern Oregon

    USGS Publications Warehouse

    LaMaskin, T.A.; Vervoort, J.D.; Dorsey, R.J.; Wright, J.E.

    2011-01-01

    This study assesses early Mesozoic provenance linkages and paleogeographic-tectonic models for the western United States based on new petrographic and detrital zircon data from Triassic and Jurassic sandstones of the "Izee" and Olds Ferry terranes of the Blue Mountains Province, northeastern Oregon. Triassic sediments were likely derived from the Baker terrane offshore accretionary subduction complex and are dominated by Late Archean (ca. 2.7-2.5 Ga), Late Paleoproterozoic (ca. 2.2-1.6 Ga), and Paleozoic (ca. 380-255 Ma) detrital zircon grains. These detrital ages suggest that portions of the Baker terrane have a genetic affinity with other Cordilleran accretionary subduction complexes of the western United States, including those in the Northern Sierra and Eastern Klamath terranes. The abundance of Precambrian grains in detritus derived from an offshore complex highlights the importance of sediment reworking. Jurassic sediments are dominated by Mesozoic detrital ages (ca. 230-160 Ma), contain significant amounts of Paleozoic (ca. 290, 380-350, 480-415 Ma), Neoproterozoic (ca. 675-575 Ma), and Mesoproterozoic grains (ca. 1.4-1.0 Ga), and have lesser quantities of Late Paleoproterozoic grains (ca. 2.1-1.7 Ga). Detrital zircon ages in Jurassic sediments closely resemble well-documented age distributions in transcontinental sands of Ouachita-Appalachian provenance that were transported across the southwestern United States and modified by input from cratonal, miogeoclinal, and Cordilleran-arc sources during Triassic and Jurassic time. Jurassic sediments likely were derived from the Cordilleran arc and an orogenic highland in Nevada that yielded recycled sand from uplifted Triassic backarc basin deposits. Our data suggest that numerous Jurassic Cordilleran basins formed close to the Cordilleran margin and support a model for moderate post-Jurassic translation (~400 km) of the Blue Mountains Province. ?? 2011 Geological Society of America.

  1. Blue light from light-emitting diodes directed at a single eye elicits a dose-dependent suppression of melatonin in horses.

    PubMed

    Walsh, C M; Prendergast, R L; Sheridan, J T; Murphy, B A

    2013-05-01

    The production of melatonin during night-time hours decodes day length for seasonally breeding animals. The use of artificial light to advance the breeding season in mares is common practice within the equine industry. Four healthy Thoroughbred mares were used to evaluate the minimum intensity of light required to inhibit serum melatonin. Mares were fitted with indwelling jugular catheters and using a crossover design blood samples were collected following 1h exposure to light (barn lighting approximately 200 lux), dark (<0.1 lux), and 3, 10, 50, and 100 lux intensities. The light source was a light-emitting diode (LED; 468 nm) directed at either a single eye or both eyes. All treatments, except the sample collected after 1 h exposure to light, occurred during the dark phase of the 24 h cycle. Serum melatonin levels were determined by radioimmunoassay. Two-way repeated measures ANOVA revealed that there was no difference between the level of melatonin inhibition achieved when light was administered to one or two eyes (P = 0.7028). One-way ANOVA of melatonin levels at light intensities of 10, 50 and 100 lux were significantly different to dark (P < 0.05) and not different to light (P > 0.05) intensities. There was no difference between melatonin levels at 3 lux (P > 0.05) and dark intensities. The threshold level of low wavelength light required to inhibit melatonin production in the horse lies between 3 and 10 lux. Melatonin inhibition can be achieved by exposing a single eye to low wavelength blue light. This is a novel finding with important implications for management of artificial lighting regimens in horses. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Persistence of Escherichia coli, Salmonella choleraesuis, Aujeszky's Disease virus and Blue Eye Disease virus in ensilages based on the solid fraction of pig faeces.

    PubMed

    Martínez-Gamba, R; Pradal-Roa, P; Castrejón, F P; Herradora, M; Galván, E; Mercado, C

    2001-10-01

    This study was carried out to determine the survival time of Escherichia coli, Salmonella choleraesuis, Aujeszky's Disease virus and Blue Eye Disease virus in ensilages based on the solid fraction of pig faeces. The four micro-organisms were inoculated into microsilos based on the solid fraction of pig faeces, sorghum and molasses. They were left for 0, 7, 14, 28 and 56 days, after which the state of each microsilo was evaluated, and isolation of the inoculated agents was attempted. The four inoculated agents were isolated only on day 0 of ensilage. The viral agents were identified through the cytopathic effect and fluorescence. It is concluded that ensilages based on the solid fraction of pig faeces appear to reduce the risk of the transmission of the agents inoculated in this study and help to reduce the environmental impact by using the solid in animal feed.

  3. The Rocky Mountain Epidemic of Bark Beetles and Blue Stain Fungi Cause Cascading Effects on Coupled Water, C and N cycles

    NASA Astrophysics Data System (ADS)

    Ewers, B. E.; Pendall, E.; Norton, U.; Reed, D.; Franks, J.; Aston, T.; Whitehouse, F.; Barnard, H. R.; Brooks, P. D.; Angstmann, J.; Massman, W. J.; Williams, D. G.; Harpold, A. A.; Biederman, J.; Edburg, S. L.; Meddens, A. J.; Gochis, D. J.; Hicke, J. A.

    2010-12-01

    The ongoing epidemic of bark beetles and their associated xylem blocking blue-stain fungi is unprecedented in Rocky Mountain subalpine forests. As this epidemic continues, we seek to improve our predictive understanding of coupled water, C and N cycles by quantifying how these cycles may become uncoupled in response to the outbreak. Our specific questions are 1) how does the rapid drop in individual tree transpiration impact the temporal and spatial extent of evapotranspiration and 2) how does the subsequent increase in soil moisture and lower C inputs and N uptake impact soil C and N fluxes? We address these questions in two forest ecosystems using eddy covariance, sap flux, leaf gas exchange, plant hydraulic conductance, vegetation characteristics and soil trace gas measurements. We applied two sampling designs 1) subdivide the lodgepole pine forest spatially into varying degrees of bark beetle and blue stain infection and 2) follow the fluxes as the outbreak continues at a point in space encompassing the range of spatial variability in mortality. The first order impact of the bark beetle and blue stain fungi is dramatic in all tree species with a greater than 50% reduction in transpiration per tree within a month of infection. This change occurs even before the characteristic red tinge occurs in the needles or before the sapwood is stained blue. Leaf stomatal conductance declines more than either the biochemical or light harvesting components of photosynthesis immediately after infestation. The annual C sink at the spruce/fir forest has declined from -2.88 to -0.57 Mg C ha-1 yr-1 from 2006 to 2009. Annual evapotranspiration (ET) over the last five years at the spruce/fir forest now has an inverse relationship with precipitation because the last two years have seen a dramatic decrease (from 73 to 59 cm/year) in ET while precipitation has increased (from ~100 to 140 cm/year). Soil moisture in both forests has increased up to 100% within one growing season in

  4. Blue Ice Moraines as an Archive of Past EAIS dynamics: Mt. Achernar as a Case Study in the Central Transantarctic Mountains

    NASA Astrophysics Data System (ADS)

    Kaplan, M. R.; Licht, K.; Winckler, G.; Schaefer, J. M.; Mathieson, C.; Bader, N.

    2014-12-01

    Observations from the interior of East Antarctica are essential for placing direct constraints on the ice sheet's history over multiple glacial cycles, which also can be used to test numerical modeling of its past dynamics. In particular, laterally extensive, blue ice or ablation moraines are important archives of the former behavior of the EAIS and WAIS during at least the Pleistocene and Holocene. We can now quantify changes in the former ice surfaces using such deposits, which have been studied for decades, but have lacked chronological information. We are carrying out 10Be-26Al-3He dating and provenance initiatives at Mt. Achernar, near the head of the Law Glacier, where there is a well-preserved archive of ice sheet history extending spatially over 5-10 km and temporally over the last few hundred thousand years, during which time the climate swung between full glacial and warm interglacial changes. Here, concentric moraines are continuous and well preserved, and the entire complex is no higher than about ~30 meters above the modern EAIS surface. The cosmogenic ages steadily progress away from the EAIS, over 103 to 105 timescales. In addition, agreement of 10Be and 26Al concentrations indicate that, at least over the long term, blue ice deposits at Mt Achernar do not have a complicated history of burial and re-exposure. This is consistent with the inferred process of blue ice moraine formation that involves debris coming up from below and accumulating on the surface, when ice encounters the Transantarctic Mountains. Based on our findings we conclude that the interior of EAIS has been relatively stable for the last few 100 kyr, with ice surface elevation changes on the order of tens of meters, including 20-30 meters since the LGM. In a net sense, the EAIS has also been getting slightly lower over the last half million years or so. We hypothesize that if the interior of the EAIS had undergone major lowering or more pronounced surface changes over the time

  5. Field evidence for fault controlled intrusion of blue-schist-bearing melange into an accretionary wedge, Island Mountain, California

    SciTech Connect

    Lamons, R.

    1985-01-01

    Two lithologic units of the Franciscan are well exposed along a loop of the Eel River at Island Mountain. They are 1) zeolite or lower grade lithic graywackes, and 2) a 0.5 km wide band of black shaly melange containing blueschist, chert, greenstone, metagraywacke, and a graywacke-hosted copper deposit. Sedimentary features were not observed in the melange. The graywacke was subdivided on the basis of presence or absence of sodium-cobaltonitrate stained K-spar. Field relationships suggest that the blueschist-bearing melange was emplaced along steep NW-dipping faults in an accretionary wedge. Mapping of S. Jewett Rock and SW Lake Mountain quadrangles show narrow anastomosing bands of the melange following NW-trending faults. East of this band, graywackes without K-spar are folded along NW/SE axes. No folds were found to the west. Other Melange bands pinch out into faults which juxtapose graywackes of different facies. The sheared melange bands are not folded and shale beds in the graywacke show little shear so the melange bands are unlikely to be sheared olistostromes. The areal extent of graywacke is about ten times that of melange shales. Assuming this pattern continues laterally and at depth, the amount of ductile material in the melange is far less than that assumed by Cloos (1982) in his flow model for melange. The ductile melange may have been forced upward by metamorphically produced volatiles, or as a result of relative plate motion. It originated at depth, moved up along the top of a subducting slab, plucking clasts, then splayed upward into pre-existing faults in the accretionary wedge.

  6. Blue Ribbon Commission, Yucca Mountain Closure, Court Actions - Future of Decommissioned Reactors, Operating Reactors and Nuclear Power - 13249

    SciTech Connect

    Devgun, Jas S.

    2013-07-01

    Issues related to back-end of the nuclear fuel cycle continue to be difficult for the commercial nuclear power industry and for the decision makers at the national and international level. In the US, the 1982 NWPA required DOE to develop geological repositories for SNF and HLW but in spite of extensive site characterization efforts and over ten billion dollars spent, a repository opening is nowhere in sight. There has been constant litigation against the DOE by the nuclear utilities for breach of the 'standard contract' they signed with the DOE under the NWPA. The SNF inventory continues to rise both in the US and globally and the nuclear industry has turned to dry storage facilities at reactor locations. In US, the Blue Ribbon Commission on America's Nuclear Future issued its report in January 2012 and among other items, it recommends a new, consent-based approach to siting of facilities, prompt efforts to develop one or more geologic disposal facilities, and prompt efforts to develop one or more consolidated storage facilities. In addition, the March 2011 Fukushima Daiichi accident had a severe impact on the future growth of nuclear power. The nuclear industry is focusing on mitigation strategies for beyond design basis events and in the US, the industry is in the process of implementing the recommendations from NRC's Near Term Task Force. (authors)

  7. Massanutten Mountain, Virginia, USA (Anaglyph)

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Massanutten Mountain lies in the Shenandoah Valley of northern Virginia. Rock layers in the mountain are folded downward in an overall 'U' shape (called a syncline) which accounts for its peculiar double ridge shape with a highly elongated valley between. The ridges have formed because they are capped with a sandstone layer which is resistant to weathering and erosion. Limestones and shales are less resistant and form the lowlands and valleys. The north and south forks of the Shenandoah River flank Massanutten Mountain and display unusually pronounced meander patterns. Other layered sedimentary rocks form other ridgeline patterns in the Allegheny Mountains, to the upper left. But the igneous and metamorphic (crystalline) rocks of the Blue Ridge Mountains erode into a very different topographic pattern to the southeast. This small area provides an excellent example rock type, geologic structure, and fluvial (stream) processes all influencing landform development.

    This anaglyph was produced by first shading a preliminary elevation model from data acquired by the Shuttle Radar Topography Mission. The stereoscopic effect was then created by generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter.

    Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on February 11, 2000. The mission used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar that flew twice on the Space Shuttle Endeavour in 1994. The Shuttle Radar Topography Mission was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C

  8. Massanutten Mountain, Virginia, USA (Anaglyph)

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Massanutten Mountain lies in the Shenandoah Valley of northern Virginia. Rock layers in the mountain are folded downward in an overall 'U' shape (called a syncline) which accounts for its peculiar double ridge shape with a highly elongated valley between. The ridges have formed because they are capped with a sandstone layer which is resistant to weathering and erosion. Limestones and shales are less resistant and form the lowlands and valleys. The north and south forks of the Shenandoah River flank Massanutten Mountain and display unusually pronounced meander patterns. Other layered sedimentary rocks form other ridgeline patterns in the Allegheny Mountains, to the upper left. But the igneous and metamorphic (crystalline) rocks of the Blue Ridge Mountains erode into a very different topographic pattern to the southeast. This small area provides an excellent example rock type, geologic structure, and fluvial (stream) processes all influencing landform development.

    This anaglyph was produced by first shading a preliminary elevation model from data acquired by the Shuttle Radar Topography Mission. The stereoscopic effect was then created by generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter.

    Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on February 11, 2000. The mission used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar that flew twice on the Space Shuttle Endeavour in 1994. The Shuttle Radar Topography Mission was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C

  9. Pale Blue Orb

    NASA Image and Video Library

    2006-09-19

    NASA Cassini casts powerful eyes on our home planet, and captures Earth, a pale blue orb, and a faint suggestion of our moon, among the glories of the Saturn system in this image taken Sept. 15, 2006.

  10. Caucasus Mountains

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Often regarded as the southeastern border of Europe, the Caucasus Mountains can be seen here stretching from the Black Sea (left) to the Caspian Sea (right). The mountain range spans 700 miles (1125 km), crossing the countries of Russian Federation, Georgia, and Azerbaijan from left to right respectively. With a snowline of approximately 11,000 feet and peaks such as Mt. Elbrus, that reach 15,000 feet, much of the snow visible in this image is present year round. Also visible in this image are apparent phytoplankton blooms in the Caspian Sea, marked by blue-green swirls.

  11. A multi-scale analysis of streamflow response to changes in evapotranspiration and soil hydrology in the Blue Ridge Mountains (Invited)

    NASA Astrophysics Data System (ADS)

    Price, K.; Jackson, C. R.

    2013-12-01

    A large amount of research exploring the relationship between watershed forest cover and streamflow quantity has been conducted in the southern Blue Ridge Mountains, particularly in association with the USFS Coweeta Hydrologic Laboratory and the Coweeta LTER. However, a clear answer to the question ';How does changing tree cover influence runoff?' has not yet emerged for guidance of policy and management. The southern Blue Ridge is the source of water reaching much of the drought-sensitive Southeastern US, and a firmer understanding of the complexities of this issue is critical for water resources management for millions of people and diverse aquatic habitats. When this question has been explored in mesoscale systems (10s to 100s km2), results indicate that watersheds with greater forest cover have greater baseflow. Associated work has shown that hydraulic conductivities in forest soils are nearly an order of magnitude greater than lawn and pasture soils in this region. Our interpretation has been that in these mesoscale systems, the compaction of soil associated with forest conversion to other land uses has played a bigger role than related changes in evapotranspiration (ET) in shaping watershed dynamics and the overall water budget. Particular influence has been seen in baseflows, we posit, due to reduced infiltration and recharge. However, nearly a century of research in small experimental watersheds at Coweeta has shown that forest ET substantially reduces streamflows, including baseflows, when soils are not substantially altered. At this smaller scale of observations, details of forest composition and species water use variability have been thoroughly considered, while in the mesoscale studies 'forest cover' is treated as regionally uniform. Current small-scale work at Coweeta has shown that hemlock decline and subsequent replacement with other species has changed the magnitude and seasonality of ET, which is detectible in streamflow quantity and timing. Here

  12. Test–Retest Repeatability of the Pupil Light Response to Blue and Red Light Stimuli in Normal Human Eyes Using a Novel Pupillometer

    PubMed Central

    Herbst, Kristina; Sander, Birgit; Milea, Dan; Lund-Andersen, Henrik; Kawasaki, Aki

    2011-01-01

    In this study, we evaluated the repeatability of pupil responses to colored light stimuli in healthy subjects using a prototype chromatic pupillometer. One eye of 10 healthy subjects was tested twice in the same day using monochromatic light exposure at two selected wavelengths (660 and 470 nm, intensity 300 cd/m2) presented continuously for 20 s. Pupil responses were recorded in real-time before, during, and after light exposure. Maximal contraction amplitude and sustained contraction amplitude were calculated. In addition, we quantified the summed pupil response during continuous light stimulation as the total area between a reference line representing baseline pupil size and the line representing actual pupil size over 20 s (area under the curve). There was no significant difference in the repeated measure compared to the first test for any of the pupil response parameters. In conclusion, we have developed a novel prototype of color pupillometer which demonstrates good repeatability in evoking and recording the pupillary response to a bright blue and red light stimulus. PMID:21442043

  13. Erosion Rates of Volcanic-ash Derived Soils in the Blue Mountains of Eastern Oregon, USA: A Comparison Across Sales in Space and Time.

    NASA Astrophysics Data System (ADS)

    Wondzell, S. M.; Clifton, C. F.; Harris, R. M.; Ritchie, J. C.

    2007-12-01

    We examined present day rates of erosion in the Blue Mountains of eastern Oregon to quantify background erosion rates to provide standards for assessing possible accelerated rates of erosion resulting from wild fire or from land-management activities such as prescribed fire. The Skookum Creek watersheds, where stream discharge and sediment yield have been recorded continuously since the watersheds were gauged in 1992, provided a watershed-scale estimate of erosion rates. We installed hillslope erosion plots on north- and south- facing slopes within the watersheds in 2002 and collected data for three years to estimate short-term, hillslope- scale erosion rates. We also collected soil samples and analyzed them for 137Cs to get a 40-yr time- integrated estimate of hillslope erosion rates. Our results showed large differences between whole-watershed sediment yields and hillslope erosion rates measured from plots, suggesting that episodic processes dominated sediment production and transport and therefore controlled watershed-scale sediment budgets. At the hillslope-scale, short-term erosion resulted primarily from digging by small mammals and trampling by elk. Visual observations at the plots suggested that annual down-slope sediment movement was usually less than one meter. There were no significant difference among slope positions, but erosion rates were significantly higher on south-facing aspects and positively correlated to the amount of bare ground. In contrast, the 137Cs data suggested that erosion rates differed with slope position. Higher erosion rates were measured in toe- and mid-slope positions, with little erosion occurring on upper slopes and ridge tops. We examine these results in light of the present-day pattern of surface soils resulting from redistribution of volcanic ash from upper- slope to lower-slope positions and the effects of disturbance, including wildfire and the preferential grazing of riparian and lower-slope positions by domestic livestock.

  14. Acute mountain sickness

    MedlinePlus

    ... occur with more severe acute mountain sickness include: Blue color to the skin (cyanosis) Chest tightness or congestion Confusion Cough Coughing up blood Decreased consciousness or withdrawal from social interaction Gray ...

  15. Assessing Past Fracture Connectivity in Geothermal Reservoirs Using Clumped Isotopes: Proof of Concept in the Blue Mountain Geothermal Field, Nevada USA

    NASA Astrophysics Data System (ADS)

    Huntington, K. W.; Sumner, K. K.; Camp, E. R.; Cladouhos, T. T.; Uddenberg, M.; Swyer, M.; Garrison, G. H.

    2015-12-01

    Subsurface fluid flow is strongly influenced by faults and fractures, yet the transmissivity of faults and fractures changes through time due to deformation and cement precipitation, making flow paths difficult to predict. Here we assess past fracture connectivity in an active hydrothermal system in the Basin and Range, Nevada, USA, using clumped isotope geochemistry and cold cathodoluminescence (CL) analysis of fracture filling cements from the Blue Mountain geothermal field. Calcite cements were sampled from drill cuttings and two cores at varying distances from faults. CL microscopy of some of the cements shows banding parallel to the fracture walls as well as brecciation, indicating that the cements record variations in the composition and source of fluids that moved through the fractures as they opened episodically. CL microscopy, δ13C and δ18O values were used to screen homogeneous samples for clumped isotope analysis. Clumped isotope thermometry of most samples indicates paleofluid temperatures of around 150°C, with several wells peaking at above 200°C. We suggest that the consistency of these temperatures is related to upwelling of fluids in the convective hydrothermal system, and interpret the similarity of the clumped isotope temperatures to modern geothermal fluid temperatures of ~160-180°C as evidence that average reservoir temperatures have changed little since precipitation of the calcite cements. In contrast, two samples, one of which was associated with fault gauge observed in drill logs, record significantly cooler temperatures of 19 and 73°C and anomalous δ13C and δ18Owater values, which point to fault-controlled pathways for downwelling meteoric fluid. Finally, we interpret correspondence of paleofluid temperatures and δ18Owater values constrained by clumped isotope thermometry of calcite from different wells to suggest past connectivity of fractures among wells within the geothermal field. Results show the ability of clumped isotope

  16. Keratoglobus and blue sclera.

    PubMed

    Biglan, A W; Brown, S I; Johnson, B L

    1977-02-01

    Five patients from two families had similar features including keratoglobus, blue scleras, hyperextensibility of the hand, wrist, and ankle joints, sensorineural conduction hearing alterations, and mottling of the teeth. Keratoglobus had been observed in all patients at, or shortly after, birth. Corneal perforations developed in seven of the ten eyes after minimal trauma. Repair of these perforations was complicated by the extremely thin corneas and six eyes had to be either enucleated or eviscerated. Histopathological examination of two of the enucleated eyes showed the corneal stromas of both eyes to be estremely thin, Bowman's membrane was absent, and Descemet's membrane was unusually thick. This condition has an autosomal-recessive inheritance pattern.

  17. Blue Saturn

    NASA Image and Video Library

    2004-03-19

    Bands and spots in Saturn's atmosphere, including a dark band south of the equator with a scalloped border, are visible in this image from the Cassini-Huygens spacecraft. The narrow angle camera took the image in blue light on Feb. 29, 2004. The distance to Saturn was 59.9 million kilometers (37.2 million miles). The image scale is 359 kilometers (223 miles) per pixel. Three of Saturn's moons are seen in the image: Enceladus (499 kilometers, or 310 miles across) at left; Mimas (398 kilometers, or 247 miles across) left of Saturn's south pole; and Rhea (1,528 kilometers, or 949 miles across) at lower right. The imaging team enhanced the brightness of the moons to aid visibility. The BL1 broadband spectral filter (centered at 451 nanometers) allows Cassini to "see" light in a part of the spectrum visible as the color blue to human eyes. Scientist can combine images made with this filter with those taken with red and green filters to create full-color composites. Scientists can also assess cloud heights by combining images from the blue filter with images taken in other spectral regions. For example, the bright clouds that form the equatorial zone are the highest in altitude and have pressures at their tops of about one quarter of Earth's atmospheric pressure at sea level. The cloud tops at middle latitudes are lower in altitude and have higher pressures of about half that found at sea level. Analysis of Saturn images like this one will be extremely useful to researchers assessing cloud altitudes during the Cassini-Huygens mission. http://photojournal.jpl.nasa.gov/catalog/PIA05383

  18. Effects of Watershed Land Use and Geomorphology on Stream Low Flows During Severe Drought Conditions in the Southern Blue Ridge Mountains, Georgia and North Carolina, United States

    EPA Science Inventory

    Land use and physiographic variability influence stream low flows, yet their interactions and relative influence remain unresolved. Our objective was to assess the influence of land use and watershed geomorphic characteristics on low-flow variability in the southern Blue Ridge Mo...

  19. Effects of Watershed Land Use and Geomorphology on Stream Low Flows During Severe Drought Conditions in the Southern Blue Ridge Mountains, Georgia and North Carolina, United States

    EPA Science Inventory

    Land use and physiographic variability influence stream low flows, yet their interactions and relative influence remain unresolved. Our objective was to assess the influence of land use and watershed geomorphic characteristics on low-flow variability in the southern Blue Ridge Mo...

  20. Is blue light, cryptochrome in the eye, and magnetite in the brain involved in the development of frontotemporal dementia and other diseases?

    PubMed

    Størmer, Fredrik C

    2015-04-01

    When cryptochrome in the retina is exposed to blue light, it undergo series of complicated chemical reactions. One of these intermediates has magnetic properties. It could be a link between the magnetic stage of cryptochrome in the retina and magnetite in the brain. A disturbance in this system could be involved in the development of frontotemporal dementia and other mental disturbances like Alzheimer's disease. There could also be a link between circadian rhythms and memory dysfunction connected to schizophrenia, type 2 diabetes, and blue light. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Angiotensin-converting enzyme inhibitors (ACEIs) and age-related maculopathy (ARM): cross-sectional findings from the Blue Mountains Eye Study.

    PubMed

    Wu, Kathy H C; Wang, Jie Jin; Rochtchina, Elena; Foran, Suriya; Ng, Martin K C; Mitchell, Paul

    2004-06-01

    To assess the relationship between the use of angiotensin-converting enzyme inhibitors (ACEIs) and prevalence of age-related maculopathy (ARM). Eligible residents aged >/= 49 years were first examined in 1992-94 (Cross-section 1, n = 3654). Of these, 2335 were re-examined in 1997-99, together with an additional 1174 who became eligible after 1994 (Cross-section 2, n = 3509). Information regarding ACEI use was obtained and retinal photographs were graded using the Wisconsin ARM Grading System. In Cross-section 1, prevalence rates of late and early stage ARM were 1.3% and 4.3% among current ACEI users, and 2.0% and 4.8% among non-current users, respectively. In Cross-section 2, prevalence rates of late and early stage ARM were 2.3% and 11.3% among current ACEI users, and 1.3% and 9.3% among non-current users, respectively. After adjusting for age, sex and smoking, neither survey found any significant association between ACEI use and prevalence of either late or early ARM. No significant cross-sectional associations were found between ACEI use and ARM prevalence in this population.

  2. Genotyping of five single nucleotide polymorphisms in the OCA2 and HERC2 genes associated with blue-brown eye color in the Japanese population.

    PubMed

    Iida, Reiko; Ueki, Misuzu; Takeshita, Haruo; Fujihara, Junko; Nakajima, Tamiko; Kominato, Yoshihiko; Nagao, Masataka; Yasuda, Toshihiro

    2009-07-01

    Human eye color is a polymorphic phenotype influenced by multiple genes. It has recently been reported that three single nucleotide polymorphisms (SNPs) within intron 1 of the OCA2 gene (rs7495174, rs4778241, rs4778138) and two SNPs in intron 86 (rs12913832) and the 3' UTR region (rs1129038) of the HERC2 gene--located in the upstream of the OCA2 locus--have a high statistical association with human eye color. The present study is the first to examine in detail the genotype and haplotype frequencies for these five SNPs in an Asian (Japanese) population (n = 523) comprising solely brown-eyed individuals. Comparison of the genotype and haplotype distributions in Japanese with those in African and European subjects revealed significant differences between Japanese and other populations. Analysis of haplotypes consisting of four SNPs at the HERC2-OCA2 locus (rs12913832/rs7495174/rs4778241/rs4778138) showed that the most frequent haplotype in the Japanese population is A-GAG (0.568), while the frequency of this haplotype is rather low in the European population, even in the brown-eyed group (0.167). The haplotype distribution in the Japanese population was significantly different from that in the brown-eyed European group (F(ST) = 0.18915). (c) 2009 John Wiley & Sons, Ltd.

  3. Growth and mortality of ponderosa pine poles thinned to various densities in the Blue Mountains of Oregon. Forest Service research paper

    SciTech Connect

    Cochran, P.H.; Barrett, J.W.

    1995-06-01

    Growth and mortality in relation to density were investigated for 24 years. High mortality rates from mountain pine beetle occurred on some plots where values for stand-density index exceeded 140. Periodic annual increments of gross basal area and cubic volume increased curvilinearly with increasing stand density, whereas periodic annual diameter increments decreased curvilinearly with increasing stand density. Mean annual increments of board-foot volume have not culminated at age 84 years.

  4. People with Increased Risk of Eye Damage from UV Light

    MedlinePlus

    ... With Increased Risk of Eye Damage from UV Light Written by: Shirley Dang Apr. 30, 2014 Everyone ... photosensitivity, though the reaction is rare. People with light-colored eyes Have blue or green eyes? Cover ...

  5. Dermal, Eye and Oral Toxicological Evaluations. Phase IV Report with Disperse Red 11, Disperse Blue 3, Solvent Red 1, and Red and Violet Mixtures

    DTIC Science & Technology

    1986-04-01

    termination of each study, animals were euthanized by administration of an intravenous injection of T-61 Euthanasia Solution and discarded. The...sacrificed at the termination of the study by administration of an intravenous injection of T-61 Euthanasia Solution and discarded. The mean Primary Eye...study are given in Table 2. No moralities and no abnormal clinicial signs were observed during the study. Erythema and edema (grades 2 and 1) was

  6. 141. View of Grandfather Mountain in the distance with cows ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    141. View of Grandfather Mountain in the distance with cows on an agricultural lease in the foreground. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  7. 53. Roanoke Mountain scenic loop road. View of a crescent ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Roanoke Mountain scenic loop road. View of a crescent overlook looking south-southwest. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  8. Eye Cancer

    MedlinePlus

    ... Cancer > Eye Cancer > Eye Cancer: Overview Request Permissions Eye Cancer: Overview Approved by the Cancer.Net Editorial ... trained to treat intraocular cancer. Parts of the eye The eye is the organ that collects light ...

  9. Eye Infections

    MedlinePlus

    Your eyes can get infections from bacteria, fungi, or viruses. Eye infections can occur in different parts of the eye and can affect just one eye or both. Two common eye infections are Conjunctivitis - also known as pinkeye. Conjunctivitis is ...

  10. [Maternity blues].

    PubMed

    Gonidakis, F

    2007-04-01

    Maternity blues is a transient change of mood that occurs mainly between the 1st and 10th day of puerpartum and is characterized by bursts of tears, mild depressive mood, anxiety and liability of mood. The frequency of maternity blues varies in different studies form 4% to 80%. A number of biological and psychosocial parameters have been studied in order to determine their correlation with maternity blues. The most well studied biological parameters are progesterone and cortizol although their relation with maternity blues has not yet been clearly defined. Stress and the emotional state of the woman during pregnancy as well as history of mood disorders or maternity blues in a previous birth are the psychosocial parameters that are more likely to correlate with the occurrence of maternity blues. Most of the authors suggest that information on maternity blues and reassurance of the woman are the best way to deal with maternity blues both on preventive and therapeutical basis.

  11. Changes in home range of breeding and post-breeding male Pearly-eyed Thrashers in the Luquillo Mountains of Puerto Rico

    Treesearch

    Jose William Beltran; Joseph M. Wunderle, Jr.; Wayne J. Arendt

    2010-01-01

    Food abundance, time of year, and stage of the reproductive cycle are important factors affecting home range size in birds. Between 23 January and 28 November 2003, we determined the home range and core area sizes for 10 radio-tagged male Pearly-eyed Thrashers (Margarops fuscatus; Mimidae) within the Luquillo Experimental Forest, northeastern Puerto Rico. We found...

  12. Not all butterfly eyes are created equal: rhodopsin absorption spectra, molecular identification, and localization of ultraviolet-, blue-, and green-sensitive rhodopsin-encoding mRNAs in the retina of Vanessa cardui.

    PubMed

    Briscoe, Adriana D; Bernard, Gary D; Szeto, Allan S; Nagy, Lisa M; White, Richard H

    2003-04-14

    Surveys of spectral sensitivities, visual pigment spectra, and opsin gene sequences have indicated that all butterfly eyes contain ultraviolet-, blue-, and green-sensitive rhodopsins. Some species also contain a fourth or fifth type, related in amino acid sequence to green-sensitive insect rhodopsins, but red shifted in absorbance. By combining electron microscopy, epi-microspectrophotometry, and polymerase chain reaction cloning, we found that the compound eye of Vanessa cardui has the typical ultrastructural features of the butterfly retina but contains only the three common insect rhodopsins. We estimated lambda-max values and relative densities of the rhodopsins in the Vanessa retina (0.72, P530; 0.12, P470; and 0.15, P360) from microspectrophotometric measurements and calculations based on a computational model of reflectance spectra. We isolated three opsin-encoding cDNA fragments that were identified with P530, P470, and P360 by homology to the well-characterized insect rhodopsin families. The retinal mosaic was mapped by opsin mRNA in situ hybridization and found to contain three kinds of ommatidia with respect to their patterns of short wavelength rhodopsin expression. In some ommatidia, P360 or P470 was expressed in R1 and R2 opposed receptor cells; in others, one cell expressed P360, whereas its complement expressed P470. P530 was expressed in the other seven cells of all ommatidia. P470-expressing cells were abundant in the ventral retina but nearly absent dorsally. Our results indicated that there are major differences between the color vision systems of nymphalid and papilionid butterflies: the nymphalid Vanessa has a simpler, trichromatic, system than do the tetrachromatic papilionids that have been studied. Copyright 2003 Wiley-Liss, Inc.

  13. Why did the UV-A-induced photoluminescent blue-green glow in trilobite eyes and exoskeletons not cause problems for trilobites?

    PubMed

    Schoenemann, Brigitte; Clarkson, Euan N K; Horváth, Gábor

    2015-01-01

    The calcitic lenses in the eyes of Palaeozoic trilobites are unique in the animal kingdom, although the use of calcite would have conveyed great advantages for vision in aquatic systems. Calcite lenses are transparent, and due to their high refractive index they would facilitate the focusing of light. In some respects, however, calcite lenses bear evident disadvantages. Birefringence would cause double images at different depths, but this is not a problem for trilobites since the difference in the paths of the ordinary and extraordinary rays is less than the diameter of the receptor cells. Another point, not discussed hitherto, is that calcite fluoresces when illuminated with UV-A. Here we show experimentally that calcite lenses fluoresce, and we discuss why fluorescence does not diminish the optical quality of these lenses and the image formed by them. In the environments in which the trilobites lived, UV-A would not have been a relevant factor, and thus fluorescence would not have disturbed or confused their visual system. We also argue that whatever the reason that calcite was never again used successfully in the visual systems of aquatic arthropods, it was not fluorescence.

  14. Eye pain

    MedlinePlus

    Ophthalmalgia; Pain - eye ... Pain in the eye can be an important symptom of a health problem. Make sure you tell your health care provider if you have eye pain that does not go away. Tired eyes or ...

  15. Purple Mountain Majesty

    NASA Image and Video Library

    2015-07-15

    NASA Mars Reconnaissance Orbite observed this image of an isolated mountain in the Southern highlands reveals a large exposure of purplish bedrock. Since HiRISE color is shifted to longer wavelengths than visible color and given relative stretches, this really means that the bedrock is roughly dark in the broad red bandpass image compared to the blue-green and near-infrared bandpass images. In the RGB (red-green-blue) color image, which excludes the near-infrared bandpass image, the bedrock appears bluish in color. This small mountain is located near the northeastern rim of the giant Hellas impact basin, and could be impact ejecta. http://photojournal.jpl.nasa.gov/catalog/PIA19854

  16. Blue Note

    ScienceCinema

    Murray Gibson

    2016-07-12

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  17. Blue Note

    SciTech Connect

    Murray Gibson

    2007-04-27

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  18. SRTM Anaglyph: Laguna Mellquina, Andes Mountains, Argentina

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This anaglyph of an area south of San Martin de Los Andes, Argentina, is the first Shuttle Radar Topography Mission (SRTM) view of the Andes Mountains, the tallest mountain chain in the western hemisphere. This particular site does not include the higher Andes peaks, but it does include steep-sided valleys and other distinctive landforms carved by Pleistocene glaciers. Elevations here range from about 700 to 2,440 meters (2,300 to 8,000 feet). This region is very active tectonically and volcanically, and the landforms provide a record of the changes that have occurred over many thousands of years. Large lakes fill the broad mountain valleys, and the spectacular scenery here makes this area a popular resort destination for Argentinians.

    This anaglyph was produced by first shading a preliminary SRTM elevation model. The stereoscopic effect was then created by generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter.

    Elevation data used in this image was acquired by the Shuttle Radar Topography Mission aboard Space Shuttle Endeavour, launched on February 11,2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies. It is managed

  19. Pluto Blue Sky

    NASA Image and Video Library

    2015-10-08

    Pluto's haze layer shows its blue color in this picture taken by the New Horizons Ralph/Multispectral Visible Imaging Camera (MVIC). The high-altitude haze is thought to be similar in nature to that seen at Saturn's moon Titan. The source of both hazes likely involves sunlight-initiated chemical reactions of nitrogen and methane, leading to relatively small, soot-like particles (called tholins) that grow as they settle toward the surface. This image was generated by software that combines information from blue, red and near-infrared images to replicate the color a human eye would perceive as closely as possible. http://photojournal.jpl.nasa.gov/catalog/PIA19964

  20. Blue Laser.

    DTIC Science & Technology

    1985-12-01

    HOLLOW CATHODE LASER FABRICATION 13 4. EXPERIENCE WITH THE BLUE LASER 18 4.1 Operational and Processing Experience 18 4.2 Performance Testing 20 5...34 -. - . •. SECTION 3 BLUE HOLLOW CATHODE LASER FABRICATION This section presents an overview of the steps taken in creating a HCL. There is...to the laser assembly. These steps can actually be considered as the final steps in laser fabrication because some of them involve adding various

  1. Eye Diseases

    MedlinePlus

    ... the back of the eye Macular degeneration - a disease that destroys sharp, central vision Diabetic eye problems ... defense is to have regular checkups, because eye diseases do not always have symptoms. Early detection and ...

  2. Eye Injuries

    MedlinePlus

    The structure of your face helps protect your eyes from injury. Still, injuries can damage your eye, sometimes severely enough that you could lose your vision. Most eye injuries are preventable. If you play sports or ...

  3. Eye Cancer

    MedlinePlus

    Cancer of the eye is uncommon. It can affect the outer parts of the eye, such as the eyelid, which are made up ... adults are melanoma and lymphoma. The most common eye cancer in children is retinoblastoma, which starts in ...

  4. Eye Allergies

    MedlinePlus

    ... Sep. 01, 2016 Eye allergies, also called allergic conjunctivitis, are quite common. They occur when the eyes ... can tear and burn. Unlike other kinds of conjunctivitis, eye allergies are not spread from person to ...

  5. Watery eyes

    MedlinePlus

    ... the most common causes of excess tearing is dry eyes . Drying causes the eyes to become uncomfortable, which stimulates the body to produce too many tears. One of the main tests for tearing is to check whether the eyes ...

  6. Christmas Mountains

    Atmospheric Science Data Center

    2013-04-17

    article title:  Christmas Mountains     View Larger ... of New Brunswick. Located above image center are the Christmas Mountains, a region of old-growth forest nestled in a remote ... date:  Mar 8, 2001 Images:  Christmas Mountains location:  Canada ...

  7. 20. GROVE OF TREES PINES, MULBERRY, JUNIPER, BLUE SPRUCE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. GROVE OF TREES -- PINES, MULBERRY, JUNIPER, BLUE SPRUCE -- TRANSPLANTED FROM NEW MEXICO MANZANO MOUNTAINS, WEST OF BUILDINGS 4 AND T-59, LOOKING NORTHWEST - U. S. Veterans Administration Medical Center, 2100 Ridgecrest Southeast, Albuquerque, Bernalillo County, NM

  8. Artificially extended photoperiod administered to pre-partum mares via blue light to a single eye: Observations on gestation length, foal birth weight and foal hair coat at birth.

    PubMed

    Nolan, Margaret B; Walsh, Caroline M; Duff, Noelle; McCrarren, Conor; Prendergast, Ralph L; Murphy, Barbara A

    2017-09-15

    In seasonally breeding animals, photoperiod perception is crucial for timing of important physiological events. In the horse, long day photoperiod influences the onset of ovulation and cyclicity, shedding of the heavier winter coat and the timing of parturition. In this compilation of studies, conducted across three breeding seasons and two countries, the impact of artificially extended day length was investigated on gestation length, foal birth weight and foal hair coat at birth. The light therapy was administered to pre-partum mares via mobile head worn masks which provided short wavelength blue light to a single eye. In Study 1, reductions in gestation lengths were observed following administration of artificially extended day length (124.8 ± 15.11 days) in the final months of pregnancy to a group of Thoroughbred mares compared to controls (P < 0.05; 339.7 ± 9.56 days vs 350.6 ± 9.13). Study 2 revealed that pre-partum exposure to artificially extended day length (104.6 ± 9.89 days) increased foal birth weight compared to controls (47.13 ± 2.93 kg vs 43.51 ± 6.14 kg; P < 0.05) in mares bred early in the year. In Study 3, artificially extended day length (87.53 ± 19.6 days) administered to pre-partum mares affected the coat condition of foals at birth with respect to hair weight (P < 0.0001) and hair length (P < 0.0001) compared to controls (0.34 ± 0.20 μg vs 0.59 ± 0.12 μg and 1.93 ± 0.56 cm vs 2.56 ± 0.32 cm, respectively). Collectively, these studies serve to highlight the influential role of the circa-annual changes in photoperiod length on the pre-partum mare for normal foetal development during the natural breeding season. It also emphasizes the potential that exists to improve breeding efficiency parameters by artificially simulating this important environmental cue in the latter stages of gestation against the backdrop of an economically driven early breeding season. Copyright © 2017 Elsevier Inc. All

  9. Blue gods, blue oil, and blue people.

    PubMed

    Fairbanks, V F

    1994-09-01

    Studies of the composition of coal tar, which began in Prussia in 1834, profoundly affected the economies of Germany, Great Britain, India, and the rest of the world, as well as medicine and surgery. Such effects include the collapse of the profits of the British indigo monopoly, the growth in economic power of Germany based on coal tar chemistry, and an economic crisis in India that led to more humane tax laws and, ultimately, the independence of India and the end of the British Empire. Additional consequences were the development of antiseptic surgery and the synthesis of a wide variety of useful drugs that have eradicated infections and alleviated pain. Many of these drugs, particularly the commonly used analgesics, sulfonamides, sulfones, and local anesthetics, are derivatives of aniline, originally called "blue oil" or "kyanol." Some of these aniline derivatives, however, have also caused aplastic anemia, agranulocytosis, and methemoglobinemia (that is, "blue people"). Exposure to aniline drugs, particularly when two or three aniline drugs are taken concurrently, seems to be the commonest cause of methemoglobinemia today.

  10. Blue jays nest in an unusual structure

    USGS Publications Warehouse

    Muths, Erin L.; Lyons, Curtis P.; Sedgwick, James A.

    2007-01-01

    We describe a successful Blue Jay (Cyanocitta cristata) nest in an unusual structure on the side of a building.  The nest was located near the edge of the species' range along the Front Range of the Rocky Mountains in Colorado.  The nest was completely obvious, suggesting that the structure itself provided adequate cover and sercurity for the jays.  Blue Jays appear to be declining in some areas of the United States such as the Southeast.  Structures such as the one we describe may be more useful in attracting Blue Jays than the nesting platforms available commercially.

  11. Trustworthy-Looking Face Meets Brown Eyes

    PubMed Central

    Kleisner, Karel; Priplatova, Lenka; Frost, Peter; Flegr, Jaroslav

    2013-01-01

    We tested whether eye color influences perception of trustworthiness. Facial photographs of 40 female and 40 male students were rated for perceived trustworthiness. Eye color had a significant effect, the brown-eyed faces being perceived as more trustworthy than the blue-eyed ones. Geometric morphometrics, however, revealed significant correlations between eye color and face shape. Thus, face shape likewise had a significant effect on perceived trustworthiness but only for male faces, the effect for female faces not being significant. To determine whether perception of trustworthiness was being influenced primarily by eye color or by face shape, we recolored the eyes on the same male facial photos and repeated the test procedure. Eye color now had no effect on perceived trustworthiness. We concluded that although the brown-eyed faces were perceived as more trustworthy than the blue-eyed ones, it was not brown eye color per se that caused the stronger perception of trustworthiness but rather the facial features associated with brown eyes. PMID:23326406

  12. Trustworthy-looking face meets brown eyes.

    PubMed

    Kleisner, Karel; Priplatova, Lenka; Frost, Peter; Flegr, Jaroslav

    2013-01-01

    We tested whether eye color influences perception of trustworthiness. Facial photographs of 40 female and 40 male students were rated for perceived trustworthiness. Eye color had a significant effect, the brown-eyed faces being perceived as more trustworthy than the blue-eyed ones. Geometric morphometrics, however, revealed significant correlations between eye color and face shape. Thus, face shape likewise had a significant effect on perceived trustworthiness but only for male faces, the effect for female faces not being significant. To determine whether perception of trustworthiness was being influenced primarily by eye color or by face shape, we recolored the eyes on the same male facial photos and repeated the test procedure. Eye color now had no effect on perceived trustworthiness. We concluded that although the brown-eyed faces were perceived as more trustworthy than the blue-eyed ones, it was not brown eye color per se that caused the stronger perception of trustworthiness but rather the facial features associated with brown eyes.

  13. BLOOD MOUNTAIN ROADLESS AREA, GEORGIA.

    USGS Publications Warehouse

    Koeppen, Robert P.; Armstrong, Michelle K.

    1984-01-01

    A mineral-resource survey of the Blood Mountain Roadless Area, Georgia, indicates that there is little promise for the occurrence of mineral and energy resources. Natural gas may be present at great depth, perhaps 5 mi down and below the overthrust sheets of the Blue Ridge Mountains, but presently available information is not adequate to evaluate the resource potential of this commodity. Further seismic studies and exploratory drilling are needed to evaluate the gas potential of this part of the Eastern Overthrust Belt.

  14. Appalachian Mountains

    Atmospheric Science Data Center

    2014-05-15

    article title:  Appalachian Mountains     View Larger Image Multi-angle views of the Appalachian Mountains, March 6, 2000 . The true-color image at left is a ... location:  United States region:  Eastern United States Order:  3 ...

  15. Appalachian Mountains

    Atmospheric Science Data Center

    2014-05-15

    article title:  Aerosols over the Appalachian Mountains     View ... Imaging SpectroRadiometer (MISR) acquired these views of the Appalachian Mountains on March 6, 2000. The image at left is a downward-looking ... location:  United States region:  Eastern United States Order:  2 ...

  16. Your Eyes

    MedlinePlus

    ... the eye and keeps it healthy. previous continue Light, Lens, Action These next parts are really cool, ... the eye. previous continue Rods and Cones Process Light The retina uses special cells called rods and ...

  17. Eye Anatomy

    MedlinePlus

    ... News About Us Donate In This Section Eye Anatomy en Español email Send this article to a ... You at Risk For Glaucoma? Childhood Glaucoma Eye Anatomy Five Common Glaucoma Tests Glaucoma Facts and Stats ...

  18. Eye emergencies

    MedlinePlus

    ... by common household products such as cleaning solutions, garden chemicals, solvents, or other types of chemicals. Fumes ... in the eye with a ball, such as indoor racket sports Images Eye First aid kit References ...

  19. Healthy Eyes

    MedlinePlus

    ... please turn Javascript on. Healthy Eyes Maintaining Your Vision Click for more information Taking good care of ... are qualified to perform eye exams. Aging and Vision Changes As you age, it is normal to ...

  20. Eye Emergencies

    MedlinePlus

    ... The Marfan Foundation Marfan & Related Disorders What is Marfan Syndrome? What are Related Disorders? What are the Signs? ... Emergencies Eye Emergencies Lung Emergencies Surgeries Eye Emergencies Marfan syndrome significantly increases your risk of retinal detachment, a ...

  1. Your Eyes

    MedlinePlus

    ... the eye and keeps it healthy. previous continue Light, Lens, Action These next parts are really cool, ... the eye. previous continue Rods and Cones Process Light The retina uses special cells called rods and ...

  2. Geology of North Mountain in eastern West Virginia

    SciTech Connect

    Dean, S.L. . Dept. of Geology); Lessing, P. ); Kulander, B.R. . Dept. of Geological Sciences)

    1994-03-01

    The North Mountain fault is one of the largest overthrusts in the folded Appalachian mountain belt and serves as the boundary between the detached Massanutten-Blue Ridge overthrust sheet (i.e. Great Valley and Blue Ridge) and Valley and Ridge fold structures in eastern West Virginia, northwestern Virginia, west-central maryland and south-central Pennsylvania. Past work has shown the sedimentary rock section on North Mountain and immediately west of the North Mountain fault to consist of an overturned sequence of Upper Ordovician to Middle Devonian strata, with a break thrust on the west side of North Mountain, placing Silurian formations against Devonian strata. Recent 1:24,000 scale mapping by the West Virginia Geological Survey has delineated this break thrust and its continuity from Maryland, through West Virginia and into Frederick County, Virginia. This previously unnamed structure, designated Back Creek fault, formed as a footwall splay from the North Mountain fault complex. The structure of North Mountain is a horse, bounded by the North Mountain fault complex in the Great Valley to the east and Back Creek fault on the west side of North Mountain. The overturned stratigraphic sequence on North Mountain reverses dip on the western flank of the mountain just east of Back Creek in Berkeley County, West Virginia, creating Back Creek syncline. This structure is a classic fault propagation fold, formed by the emplacement of North Mountain fault and extending from Maryland into Frederick County, Virginia.

  3. Stone Mountain

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This color image taken by the panoramic camera onboard the Mars Exploration Rover Opportunity shows the part of the rock outcrop dubbed Stone Mountain at Meridiani Planum, Mars. Scientists are examining Stone Mountain with the instruments on the rover's instrument deployment device, or 'arm,' in search of clues about the composition of the rock outcrop. [figure removed for brevity, see original site] A Patch of Stone (Figure credit: NASA/JPL/Cornell/USGS)

    The colorless square in this color image of the martian rock formation called Stone Mountain is one portion of the rock being analyzed with tools on the Mars Exploration Rover Opportunity's instrument deployment device, or 'arm.' The square area is approximately 3 centimeters (1.2 inches) across. Stone Mountain is located within the rock outcrop on Meridiani Planum, Mars. The image was taken by the rover's panoramic camera.

  4. Stone Mountain

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This color image taken by the panoramic camera onboard the Mars Exploration Rover Opportunity shows the part of the rock outcrop dubbed Stone Mountain at Meridiani Planum, Mars. Scientists are examining Stone Mountain with the instruments on the rover's instrument deployment device, or 'arm,' in search of clues about the composition of the rock outcrop. [figure removed for brevity, see original site] A Patch of Stone (Figure credit: NASA/JPL/Cornell/USGS)

    The colorless square in this color image of the martian rock formation called Stone Mountain is one portion of the rock being analyzed with tools on the Mars Exploration Rover Opportunity's instrument deployment device, or 'arm.' The square area is approximately 3 centimeters (1.2 inches) across. Stone Mountain is located within the rock outcrop on Meridiani Planum, Mars. The image was taken by the rover's panoramic camera.

  5. Blue Light Protects Against Temporal Frequency Sensitive Refractive Changes

    PubMed Central

    Rucker, Frances; Britton, Stephanie; Spatcher, Molly; Hanowsky, Stephan

    2015-01-01

    Purpose Time spent outdoors is protective against myopia. The outdoors allows exposure to short-wavelength (blue light) rich sunlight, while indoor illuminants can be deficient at short-wavelengths. In the current experiment, we investigate the role of blue light, and temporal sensitivity, in the emmetropization response. Methods Five-day-old chicks were exposed to sinusoidal luminance modulation of white light (with blue; N = 82) or yellow light (without blue; N = 83) at 80% contrast, at one of six temporal frequencies: 0, 0.2, 1, 2, 5, 10 Hz daily for 3 days. Mean illumination was 680 lux. Changes in ocular components and corneal curvature were measured. Results Refraction, eye length, and choroidal changes were dependent on the presence of blue light (P < 0.03, all) and on temporal frequency (P < 0.03, all). In the presence of blue light, refraction did not change across frequencies (mean change −0.24 [diopters] D), while in the absence of blue light, we observed a hyperopic shift (>1 D) at high frequencies, and a myopic shift (>−0.6 D) at low frequencies. With blue light there was little difference in eye growth across frequencies (77 μm), while in the absence of blue light, eyes grew more at low temporal frequencies and less at high temporal frequencies (10 vs. 0.2 Hz: 145 μm; P < 0.003). Overall, neonatal astigmatism was reduced with blue light. Conclusions Illuminants rich in blue light can protect against myopic eye growth when the eye is exposed to slow changes in luminance contrast as might occur with near work. PMID:26393671

  6. Blue Light Protects Against Temporal Frequency Sensitive Refractive Changes.

    PubMed

    Rucker, Frances; Britton, Stephanie; Spatcher, Molly; Hanowsky, Stephan

    2015-09-01

    Time spent outdoors is protective against myopia. The outdoors allows exposure to short-wavelength (blue light) rich sunlight, while indoor illuminants can be deficient at short-wavelengths. In the current experiment, we investigate the role of blue light, and temporal sensitivity, in the emmetropization response. Five-day-old chicks were exposed to sinusoidal luminance modulation of white light (with blue; N = 82) or yellow light (without blue; N = 83) at 80% contrast, at one of six temporal frequencies: 0, 0.2, 1, 2, 5, 10 Hz daily for 3 days. Mean illumination was 680 lux. Changes in ocular components and corneal curvature were measured. Refraction, eye length, and choroidal changes were dependent on the presence of blue light (P < 0.03, all) and on temporal frequency (P < 0.03, all). In the presence of blue light, refraction did not change across frequencies (mean change -0.24 [diopters] D), while in the absence of blue light, we observed a hyperopic shift (>1 D) at high frequencies, and a myopic shift (>-0.6 D) at low frequencies. With blue light there was little difference in eye growth across frequencies (77 μm), while in the absence of blue light, eyes grew more at low temporal frequencies and less at high temporal frequencies (10 vs. 0.2 Hz: 145 μm; P < 0.003). Overall, neonatal astigmatism was reduced with blue light. Illuminants rich in blue light can protect against myopic eye growth when the eye is exposed to slow changes in luminance contrast as might occur with near work.

  7. Eye development.

    PubMed

    Baker, Nicholas E; Li, Ke; Quiquand, Manon; Ruggiero, Robert; Wang, Lan-Hsin

    2014-06-15

    The eye has been one of the most intensively studied organs in Drosophila. The wealth of knowledge about its development, as well as the reagents that have been developed, and the fact that the eye is dispensable for survival, also make the eye suitable for genetic interaction studies and genetic screens. This article provides a brief overview of the methods developed to image and probe eye development at multiple developmental stages, including live imaging, immunostaining of fixed tissues, in situ hybridizations, and scanning electron microscopy and color photography of adult eyes. Also summarized are genetic approaches that can be performed in the eye, including mosaic analysis and conditional mutation, gene misexpression and knockdown, and forward genetic and modifier screens.

  8. 17. Rocky Mountain viaduct. This steel girder viaduct was built ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Rocky Mountain viaduct. This steel girder viaduct was built in 1942. All of the reinforced concrete was faced with a rustic stone facade. View is to east. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  9. Periodic Burning In Table Mountain-Pitch Pine Stands

    Treesearch

    Russell B. Randles; David H. van Lear; Thomas A. Waldrop; Dean M. Simon

    2002-01-01

    Abstract - The effects of multiple, low intensity burns on vegetation and wildlife habitat in Table Mountain (Pinus pungens Lamb.)-pitch (Pinus rigida Mill.) pine communities were studied in the Blue Ridge Mountains of North Carolina. Treatments consisted of areas burned from one to four times at 3-4 year...

  10. 18. Rocky Mountain Viaduct. This view shows the stone faced ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Rocky Mountain Viaduct. This view shows the stone faced arched piers. It is the only structure on the parkway with this feature. View is facing east. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  11. 245. Rocky Mountain Viaduct. This steel girder viaduct was built ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    245. Rocky Mountain Viaduct. This steel girder viaduct was built in 1942. All of the reinforced concrete was faced with a rusticated stone. It is the only structure on the parkway with stone faced arched piers. The view is facing east. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  12. Diabetes eye exams

    MedlinePlus

    Diabetic retinopathy - eye exams; Diabetes - eye exams; Glaucoma - diabetic eye exam; Macular edema - diabetic eye exam ... if the doctor who takes care of your diabetes checks your eyes, you need an eye exam ...

  13. The Blue Bottle Revisited.

    ERIC Educational Resources Information Center

    Vandaveer, Walter R., IV; Mosher, Mel

    1997-01-01

    Presents a modification of the classic Blue Bottle demonstration that involves the alkaline glucose reduction of methylene blue. Uses other indicators in the classic Blue Bottle to produce a rainbow of colors. (JRH)

  14. The Blue Bottle Revisited.

    ERIC Educational Resources Information Center

    Vandaveer, Walter R., IV; Mosher, Mel

    1997-01-01

    Presents a modification of the classic Blue Bottle demonstration that involves the alkaline glucose reduction of methylene blue. Uses other indicators in the classic Blue Bottle to produce a rainbow of colors. (JRH)

  15. Eye Health

    PubMed Central

    Connell, A. M. S.

    1988-01-01

    The status of eye care in the Caribbean is discussed. Methods of primary eye care providers at all levels from primary to tertiary in the region are presented against a background of the major causes of blindness, cataract, glaucoma, and diabetic retinopathy. Epidemiological surveys examining prevalence, risk factors, and intervention programs are being undertaken. PMID:3404562

  16. Eyes - bulging

    MedlinePlus

    ... emotional support is important. When to Contact a Medical Professional Call your health care provider if: You have bulging eyes and the cause has not yet been diagnosed. Bulging eyes are accompanied by other symptoms. ... The provider will ask about your medical history and do a physical exam. Some questions ...

  17. Nobel Prize for blue LEDs

    NASA Astrophysics Data System (ADS)

    Kraftmakher, Yaakov

    2015-05-01

    A brief review of lighting technologies is presented. Unavoidable restrictions for incandescent light bulbs caused by the Planck distribution and properties of the human eye are illustrated. The efficiency and luminous efficacy of thermal radiation are calculated for various temperatures; the results clearly show the limitations for thermal radiators. The only way to overcome these limitations is using non-thermal radiators, such as fluorescent lamps and light-emitting diodes (LEDs). Unique advantages of LEDs undoubtedly made a revolution in this field. A crucial element of this progress is the blue LEDs (Nobel Prize 2014). Some experiments with a blue and a green LED are described: (i) the luminescence triggered in a green-yellow phosphor inside a white LED by the blue LED; (ii) radiant spectra and ‘efficiency droop’ in the LEDs; (iii) modulation of the blue LED up to 4 MHz; and (iv) the h/e ratio from the turn-on voltage of the green LED. The experiments are suitable for undergraduate laboratories and usable as classroom demonstrations.

  18. Eyes in the Sky

    NASA Technical Reports Server (NTRS)

    2006-01-01

    These shape-shifting galaxies have taken on the form of a giant mask. The icy blue eyes are actually the cores of two merging galaxies, called NGC 2207 and IC 2163, and the mask is their spiral arms. The false-colored image consists of infrared data from NASA's Spitzer Space Telescope (red) and visible data from NASA's Hubble Space Telescope (blue/green).

    NGC 2207 and IC 2163 met and began a sort of gravitational tango about 40 million years ago. The two galaxies are tugging at each other, stimulating new stars to form. Eventually, this cosmic ball will come to an end, when the galaxies meld into one. The dancing duo is located 140 million light-years away in the Canis Major constellation.

    The infrared data from Spitzer highlight the galaxies' dusty regions, while the visible data from Hubble indicates starlight. In the Hubble-only image (not pictured here), the dusty regions appear as dark lanes.

    The Hubble data correspond to light with wavelengths of .44 and .55 microns (blue and green, respectively). The Spitzer data represent light of 8 microns.

  19. Eyes in the Sky

    NASA Technical Reports Server (NTRS)

    2006-01-01

    These shape-shifting galaxies have taken on the form of a giant mask. The icy blue eyes are actually the cores of two merging galaxies, called NGC 2207 and IC 2163, and the mask is their spiral arms. The false-colored image consists of infrared data from NASA's Spitzer Space Telescope (red) and visible data from NASA's Hubble Space Telescope (blue/green).

    NGC 2207 and IC 2163 met and began a sort of gravitational tango about 40 million years ago. The two galaxies are tugging at each other, stimulating new stars to form. Eventually, this cosmic ball will come to an end, when the galaxies meld into one. The dancing duo is located 140 million light-years away in the Canis Major constellation.

    The infrared data from Spitzer highlight the galaxies' dusty regions, while the visible data from Hubble indicates starlight. In the Hubble-only image (not pictured here), the dusty regions appear as dark lanes.

    The Hubble data correspond to light with wavelengths of .44 and .55 microns (blue and green, respectively). The Spitzer data represent light of 8 microns.

  20. Black Eye

    MedlinePlus

    ... Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center Global Ophthalmology Guide Academy Publications EyeNet Ophthalmology Information for: International Ophthalmologists Media Medical Students Patients and Public Technicians and Nurses ...

  1. Eye Symptoms

    MedlinePlus

    ... Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center Global Ophthalmology Guide Academy Publications EyeNet Ophthalmology Information for: International Ophthalmologists Media Medical Students Patients and Public Technicians and Nurses ...

  2. Eye Infections

    MedlinePlus

    ... become red, he probably has a condition called conjunctivitis . Also known as pinkeye, this inflammation, which can be painful and itchy, ... bacteria, antibiotic eye drops are the usual treatment. Conjunctivitis caused by viruses should not be treated with ...

  3. Scanning technique for tracking small eye-movements

    NASA Technical Reports Server (NTRS)

    Kelly, D. H.; Crane, H. D.

    1972-01-01

    Scanning technique images spot of blue light on fundus, measures variations in reflectance of spot and compares reflectance pattern with a stored reference pattern. Method then converts the difference from stored pattern into infrared eye motion.

  4. Smoking, socioeconomic factors, and age-related cataract: The Singapore Malay Eye study.

    PubMed

    Wu, Renyi; Wang, Jie Jin; Mitchell, Paul; Lamoureux, Ecosse L; Zheng, Yingfeng; Rochtchina, Elena; Tan, Ava G; Wong, Tien Yin

    2010-08-01

    To describe the relationship of smoking, sex, and socioeconomic factors with age-related cataract in Malay adults in Singapore. In a population-based study, 3280 Malay individuals aged 40 to 80 years participated (78.7% response rate). All had interviews, systemic examination, and laboratory investigations. Lens opacity was graded from slitlamp and retroillumination photographs using the Wisconsin Cataract Grading System. Smoking-cataract associations were compared with the Blue Mountains Eye Study in Australia. Of 2927 participants (89.2%) with gradable lens photographs, 1338 (45.7%) had cataract. After adjusting for age, sex, body mass index, hypertension, and diabetes, current smokers had a higher prevalence of nuclear cataract (odds ratio [OR], 2.06; 95% confidence interval [CI], 1.46-2.98), cortical cataract (OR, 1.33; 95% CI, 1.02-1.74), posterior subcapsular cataract (OR, 1.39; 95% CI, 1.02-1.91), or any cataract (OR, 1.48; 95% CI, 1.10-1.99). These associations were not seen in the Blue Mountains Eye Study. Primary or lower education (OR, 1.67; 95% CI, 1.06-2.64) and low monthly income (OR, 1.43; 95% CI, 1.09-1.87) were both associated with nuclear cataract, while small-sized public housing was associated with posterior subcapsular cataract (OR, 1.70; 95% CI, 1.28-2.25). Among men, 43.5% currently smoked compared with only 3.2% of women. The population attributable risk of nuclear cataract due to smoking was estimated to be 17.6% in men. Smoking and indicators of low socioeconomic status were associated with cataract in Malay persons, with 1 in 6 nuclear cataract cases in men attributable to smoking. Smoking-cataract associations were stronger in Malay than in white persons.

  5. Preventing Eye Injuries

    MedlinePlus

    ... Stories Español Eye Health / Eye Health A-Z Eye Injuries Sections Preventing Eye Injuries Recognizing and Treating ... Infographic Five Steps to Safer Champagne Celebrations Preventing Eye Injuries Reviewed by: Brenda Pagan-Duran MD Mar. ...

  6. Blue bubble in Carina

    NASA Image and Video Library

    2016-02-22

    Sparkling at the centre of this beautiful NASA/ESA Hubble Space Telescope image is a Wolf–Rayet star known as WR 31a, located about 30 000 light-years away in the constellation of Carina (The Keel). The distinctive blue bubble appearing to encircle WR 31a, and its uncatalogued stellar sidekick, is a Wolf–Rayet nebula — an interstellar cloud of dust, hydrogen, helium and other gases. Created when speedy stellar winds interact with the outer layers of hydrogen ejected by Wolf–Rayet stars, these nebulae are frequently ring-shaped or spherical. The bubble — estimated to have formed around 20 000 years ago — is expanding at a rate of around 220 000 kilometres per hour! Unfortunately, the lifecycle of a Wolf–Rayet star is only a few hundred thousand years — the blink of an eye in cosmic terms. Despite beginning life with a mass at least 20 times that of the Sun, Wolf–Rayet stars typically lose half their mass in less than 100 000 years. And WR 31a is no exception to this case. It will, therefore, eventually end its life as a spectacular supernova, and the stellar material expelled from its explosion will later nourish a new generation of stars and planets.

  7. Topographic View of Ceres Mountain

    NASA Image and Video Library

    2015-09-30

    This view, made using images taken by NASA's Dawn spacecraft, features a tall conical mountain on Ceres. Elevations span a range of about 5 miles (8 kilometers) from the lowest places in this region to the highest terrains. Blue represents the lowest elevation, and brown is the highest. The white streaks seen running down the side of the mountain are especially bright parts of the surface. The image was generated using two components: images of the surface taken during Dawn's High Altitude Mapping Orbit (HAMO) phase, where it viewed the surface at a resolution of about 450 feet (140 meters) per pixel, and a shape model generated using images taken at varying sun and viewing angles during Dawn's lower-resolution Survey phase. The image of the region is color-coded according to elevation, and then draped over the shape model to give this view. http://photojournal.jpl.nasa.gov/catalog/PIA19976

  8. Zagros Mountains, Iran, SRTM Shaded Relief Anaglyph

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The Zagros Mountains in Iran offer a visually stunning topographic display of geologic structure in layered sedimentary rocks. This scene is nearly 100 kilometers (62 miles) wide but is only a small part of similar terrain that covers much of southern Iran. This area is actively undergoing crustal shortening, as global tectonics moves Arabia toward Asia. Consequently, layers of sedimentary rock are folding much like a carpet will fold if pushed. The convex upward folds create structures called anticlines, which are prominently seen here. The convex downward folds (between the anticlines) create structures called synclines, which are mostly buried and hidden by sediments eroding off the anticlines. Layers having differing erosional resistance create distinctive patterns, often sawtooth triangular facets, that encircle the anticlines. Local relief between the higher mountain ridges and their intervening valleys is about 1,200 meters (about 4,000 feet).

    Salt extrusions and salt 'glaciers' are another set of geologic features readily evident in the topography. Salt deposits, likely created by the evaporation of an ancient inland sea, were buried by the sediments that now make up the layers of the anticlines and synclines. But salt is less dense than most other rocks, so it tends to migrate upward through Earth's crust in vertical columns called 'diapirs'. The compressive folding process has probably facilitated the formation of these diapirs, and the diapirs, in turn, are probably enhancing some anticlines by 'inflating' them with salt. Where the diapirs reach the surface, the salt extrudes, much like lava from a volcano, and the salt flows. Two prominent salt flows are evident in the same valley, leaking from neighboring anticlines, just north of the scene center.

    This anaglyph was created by deriving a shaded relief image from the SRTM data, draping it back over the SRTM elevation model, and then generating two differing perspectives, one for each eye

  9. Zagros Mountains, Iran, SRTM Shaded Relief Anaglyph

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The Zagros Mountains in Iran offer a visually stunning topographic display of geologic structure in layered sedimentary rocks. This scene is nearly 100 kilometers (62 miles) wide but is only a small part of similar terrain that covers much of southern Iran. This area is actively undergoing crustal shortening, as global tectonics moves Arabia toward Asia. Consequently, layers of sedimentary rock are folding much like a carpet will fold if pushed. The convex upward folds create structures called anticlines, which are prominently seen here. The convex downward folds (between the anticlines) create structures called synclines, which are mostly buried and hidden by sediments eroding off the anticlines. Layers having differing erosional resistance create distinctive patterns, often sawtooth triangular facets, that encircle the anticlines. Local relief between the higher mountain ridges and their intervening valleys is about 1,200 meters (about 4,000 feet).

    Salt extrusions and salt 'glaciers' are another set of geologic features readily evident in the topography. Salt deposits, likely created by the evaporation of an ancient inland sea, were buried by the sediments that now make up the layers of the anticlines and synclines. But salt is less dense than most other rocks, so it tends to migrate upward through Earth's crust in vertical columns called 'diapirs'. The compressive folding process has probably facilitated the formation of these diapirs, and the diapirs, in turn, are probably enhancing some anticlines by 'inflating' them with salt. Where the diapirs reach the surface, the salt extrudes, much like lava from a volcano, and the salt flows. Two prominent salt flows are evident in the same valley, leaking from neighboring anticlines, just north of the scene center.

    This anaglyph was created by deriving a shaded relief image from the SRTM data, draping it back over the SRTM elevation model, and then generating two differing perspectives, one for each eye

  10. Visually guided eye growth in the squid.

    PubMed

    Turnbull, Philip R K; Backhouse, Simon; Phillips, John R

    2015-09-21

    Eyes with refractive error have reduced visual acuity and are rarely found in the wild. Vertebrate eyes possess a visually guided emmetropisation process within the retina which detects the sign of defocus, and regulates eye growth to align the retina at the focal plane of the eye's optical components to avoid the development of refractive error, such as myopia, an increasing problem in humans. However, the vertebrate retina is complex, and it is not known which of the many classes of retinal neurons are involved. We investigated whether the camera-type eye of an invertebrate, the squid, displays visually guided emmetropisation, despite squid eyes having a simple photoreceptor-only retina. We exploited inherent longitudinal chromatic aberration (LCA) to create disparate focal lengths within squid eyes. We found that squid raised under orange light had proportionately longer eyes and more myopic refractions than those raised under blue light, and when switched between wavelengths, eye size and refractive status changed appropriately within a few days. This demonstrates that squid eye growth is visually guided, and suggests that the complex retina seen in vertebrates may not be required for emmetropisation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Our Changing Land: Stone Mountain State Park. An Environmental Education Learning Experience Designed for Grades 4-6.

    ERIC Educational Resources Information Center

    Trivette, Larry

    Stone Mountain State Park's environmental education learning experience, Our Changing Land, introduces the student to the geology of the Blue Ridge Mountains, with emphasis on Stone Mountain, through a series of hands-on activities. The learning experience is designed for grades 4-6 and meets curriculum objectives of the standard course of study…

  12. Functional and structural effect of intravitreal indocyanine green, triamcinolone acetonide, trypan blue, and brilliant blue g on rat retina.

    PubMed

    Creuzot-Garcher, Catherine; Acar, Niyazi; Passemard, Marie; Bidot, Samuel; Bron, Alain; Bretillon, Lionel

    2010-09-01

    The purpose of this study was to evaluate the functional and structural damage of the retina after intravitreal injections of four different dyes in the rat. Rats were injected intravitreally with indocyanine green (ICG), trypan blue, triamcinolone acetonide, or brilliant blue G in the right eye. The other eye was injected with saline and served as a control. Simultaneous bilateral electroretinograms were recorded before injection and 7 and 28 days after injection. Histology and immunohistochemistry analyses with antibodies recognizing glial fibrillary acidic protein and protein kinase C were performed 28 days after the initial injection on both eyes. Seven days after dye injection, the electroretinogram response of the treated eyes was altered in each group. At 1 month, eyes injected with triamcinolone acetonide, trypan blue, or brilliant blue G fully recovered, whereas eyes treated with ICG had A-wave and B-wave reduction of 65% and 63%, respectively. The inner nuclear layer thickness was statistically decreased in the ICG group (P = 0.003) but not with other dyes. Protein kinase C staining was decreased in the ICG group only, but no abnormal qualitative staining was found with either glial fibrillary acidic protein or protein kinase C antibodies with any dye. Among the four tested dyes, only ICG led to functional and structural retinal damage.

  13. Eye and orbit ultrasound

    MedlinePlus

    Echography - eye orbit; Ultrasound - eye orbit; Ocular ultrasonography; Orbital ultrasonography ... ophthalmology department of a hospital or clinic. Your eye is numbed with medicine (anesthetic drops). The ultrasound ...

  14. Eye Twitching

    MedlinePlus

    ... aspects of life. Hemifacial spasm involves twitches of muscles on one side of the face, including the eyelid. Eye twitching usually goes away on its own within a few days or weeks with rest, stress relief and decreased caffeine. Schedule an appointment with your doctor if: The ...

  15. Googly Eyes

    ERIC Educational Resources Information Center

    Boss, Susan

    2009-01-01

    Beverage take-out trays are funky in their form and function. In this article, the author describes how to make googly eye masks out of discarded take-out trays and other common recycled or discarded materials. (Contains 1 online resource.)

  16. 2. EAGLE MOUNTAIN SWITCHYARD. EAGLE MOUNTAIN PUMP PLANT CAN BE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. EAGLE MOUNTAIN SWITCHYARD. EAGLE MOUNTAIN PUMP PLANT CAN BE SEEN THROUGH SWITCHYARD IN BACKGROUND. 165MM LENS. - Eagle Mountain Pump Plant, Ten miles north of Route 10, southeast of Eagle Mountain, Eagle Mountain, Riverside County, CA

  17. Methylene blue test

    MedlinePlus

    ... determine the type or to treat methemoglobinemia , a blood disorder. ... Methemoglobinemia - methylene blue test ... Normally, methylene blue quickly lowers the level of ... Some labs use different measurements or test different samples. ...

  18. The Blue Water

    ERIC Educational Resources Information Center

    Berger, J. Joel

    1973-01-01

    Describes some of the advantages of an elementary science activity in which students discover that blowing through a straw into a bromthymol blue solution changes the color to yellow. Directions are provided for preparing the bromthymol blue solution. (JR)

  19. Ball color, eye color, and a reactive motor skill.

    PubMed

    Rowe, P J; Evans, P

    1994-08-01

    Researchers investigating performance differences between light- and dark-eyed individuals have indicated that dark-eyed individuals perform better on reactive activities than light-eyed individuals. College students (61 men, 64 women) performed a forehand rally with different colored racquetballs. Eye color, sex, and total hits were recorded for each subject. Men scored significantly better with balls of each color than did women. Dark-eyed men performed better than other subjects and performance was better with blue balls than yellow or green balls.

  20. The eyes and vision of butterflies.

    PubMed

    Arikawa, Kentaro

    2017-03-22

    Butterflies use colour vision when searching for flowers. Unlike the trichromatic retinas of humans (blue, green, and red cones; plus rods) and honeybees (ultraviolet, blue, and green photoreceptors), butterfly retinas typically have six or more photoreceptor classes with distinct spectral sensitivities. The eyes of the Japanese yellow swallowtail (Papilio xuthus) contain ultraviolet, violet, blue, green, red and broad-band receptors, with each ommatidium housing nine photoreceptor cells in one of three fixed combinations. The Papilio eye is thus a random patchwork of three types of spectrally heterogeneous ommatidia. To determine whether Papilio use all of their receptors to see colours, we measured their ability to discriminate monochromatic lights of slightly different wavelengths. We found that Papilio can detect differences as small as 1-2 nm in three wavelength regions, rivalling human performance. We then used mathematical modelling to infer which photoreceptors are involved in wavelength discrimination. Our simulation indicated that the Papilio vision is tetrachromatic, employing the ultraviolet, blue, green and red receptors. The random array of three ommatidial types is a common feature in butterflies. To address the question of how butterflies' spectrally complex eyes evolved, we studied their developmental process. We have found that the development of butterfly eyes shares its molecular logic with that of Drosophila: the three-way stochastic expression pattern of the transcription factor Spineless determines the fate of ommatidia, creating the random array in Papilio. This article is protected by copyright. All rights reserved.

  1. Blue Orb on the Horizon

    NASA Image and Video Library

    2014-05-01

    This view from NASA's Cassini spacecraft features a blue planet, imaged by Cassini for the first time. Uranus is a pale blue in this natural color image because its visible atmosphere contains methane gas and few aerosols or clouds. Methane on Uranus -- and its sapphire-colored sibling, Neptune -- absorbs red wavelengths of incoming sunlight, but allows blue wavelengths to escape back into space, resulting in the predominantly bluish color seen here. Cassini imaging scientists combined red, green and blue spectral filter images to create a final image that represents what human eyes might see from the vantage point of the spacecraft. Uranus has been brightened by a factor of 4.5 to make it more easily visible. The outer portion of Saturn's A ring, seen at bottom right, has been brightened by a factor of two. The bright ring cutting across the image center is Saturn's narrow F ring. Uranus was approximately 28.6 astronomical units from Cassini and Saturn when this view was obtained. An astronomical unit is the average distance from Earth to the sun, equal to 93,000,000 miles (150,000,000 kilometers). This view was acquired by the Cassini narrow-angle camera at a distance of approximately 614,300 miles (988,600 kilometers) from Saturn on April 11, 2014. Image scale at Uranus is approximately 16,000 miles (25,700 kilometers) per pixel. Image scale at Saturn's rings is approximately 4 miles (6 kilometers) per pixel. In the image, the disk of Uranus is just barely resolved. The solar phase angle at Uranus, seen from Cassini, is 11.9 degrees. http://photojournal.jpl.nasa.gov/catalog/PIA17178

  2. Preliminary study on eye colour in Japanese macaques (Macaca fuscata) in their natural habitat.

    PubMed

    Zhang, Peng; Watanabe, Kunio

    2007-04-01

    Eye colour in Japanese macaques shows apparent differences between individuals, continuously ranging from orange (bright), through shades of yellow and hazel-blue to dark blue (dark). We arbitrarily classified them into either 'yellow' eyes or 'blue' eyes based on the yellow area occupying in the iris' peripupillary ring. Most Japanese macaques have yellow eyes after infant phase, whilst 19, 17, 12, and 15% of monkeys (>6 months, sexes combined) have blue-eye in studied two groups of Shodoshima and two groups of Takasakiyama, respectively. Frequency of eye colour did not differ between males and females, but significantly differed in each age class. Blue eyes significantly more frequently occurred in newborns, infants and aged monkeys than in juveniles and prime adults. Data from mother-infant pairs indicated eye colour could be inherited from their parents. A case of asymmetric eye colour in Japanese macaques was found from a sample of 1962 individuals. Eye colour variation of Japanese macaques was discussed in relation to those of humans and rhesus macaques. A possible evolutionary model of eye colour in Japanese macaques was discussed.

  3. Blue Origin testing

    NASA Image and Video Library

    2012-04-20

    NASA Administrator Charles Bolden (r) discusses the upcoming testing of Blue Origin's BE-3 engine thrust chamber assembly with Steve Knowles, Blue Origin project manager, at the E-1 Test Stand during an April 20, 2012, visit to Stennis Space Center. Blue Origin is one of NASA's partners developing innovative systems to reach low-Earth orbit.

  4. 76 FR 35873 - Blue Heron Hydro LLC; Notice of Application Ready for Environmental Analysis and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ...] Blue Heron Hydro LLC; Notice of Application Ready for Environmental Analysis and Soliciting Comments... Heron Hydro LLC. e. Name of Project: Ball Mountain Dam Hydroelectric Project. f. Location: At the U.S..., Blue Heron Hydro LLC, 113 Bartlett Road, Plainfield, Vermont 05667. (802) 454-1874. i. FERC Contact:...

  5. Landscape patterns of phenotypic variation and population structuring in a selfing grass, Elymus glaucus (blue wildrye).

    Treesearch

    Vicky J. Erickson; Nancy L. Mandel; Frank C. Sorensen

    2004-01-01

    Source-related phenotypic variance was investigated in a common garden study of populations of Elymus glaucus Buckley (blue wildrye) from the Blue Mountain Ecological Province of northeastern Oregon and adjoining Washington. The primary objective of this study was to assess geographic patterns of potentially adaptive differentiation in this self-...

  6. Geology of the Southern Appalachian Mountains

    USGS Publications Warehouse

    Clark, Sandra H.B.

    2008-01-01

    The Southern Appalachian Mountains includes the Blue Ridge province and parts of four other physiographic provinces. The Blue Ridge physiographic province is a high, mountainous area bounded by several named mountain ranges (including the Unaka Mountains and the Great Smoky Mountains) to the northwest, and the Blue Ridge Mountains to the southeast. Metamorphic rocks of the mountains include (1) fragments of a billion-year-old supercontinent, (2) thick sequences of sedimentary rock that were deposited in subsiding (sinking) basins on the continent, (3) sedimentary and volcanic rocks that were deposited on the sea floor, and (4) fragments of oceanic crust. Most of the rocks formed as sediments or volcanic rocks on ocean floors, islands, and continental plates; igneous rocks formed when crustal plates collided, beginning about 450 million years ago. The collision between the ancestral North American and African continental plates ended about 270 million years ago. Then, the continents began to be stretched, which caused fractures to open in places throughout the crust; these fractures were later filled with sediment. This product (U.S. Geological Survey Scientific Investigations Map 2830) consists of a geologic map of the Southern Appalachian Mountains overlain on a shaded-relief background. The map area includes parts of southern Virginia, eastern West Virginia and Tennessee, western North and South Carolina, northern Georgia and northeastern Alabama. Photographs of localities where geologic features of interest can be seen accompany the map. Diagrams show how the movement of continental plates over many millions of years affected the landscapes seen today, show how folds and faults form, describe important mineral resources of the region, and illustrate geologic time. This two-sided map is folded into a convenient size (5x9.4 inches) for use in the field. The target audience is high school to college earth science and geology teachers and students; staffs of

  7. Eye Complications in IBD

    MedlinePlus

    ... Home > Resources > Eye Complications in IBD Go Back Eye Complications in IBD Email Print + Share Approximately 10% ... doctor’s attention sooner rather than later. TYPES OF EYE DISORDERS UVEITIS One of the most common eye ...

  8. Eye Injuries at Work

    MedlinePlus

    ... Ophthalmologist Patient Stories Español Eye Health / Tips & Prevention Eye Injuries Sections Preventing Eye Injuries Recognizing and Treating ... Numbers — Infographic Five Steps to Safer Champagne Celebrations Eye Injuries at Work Edited by: Shirley Dang Feb. ...

  9. Conjunctivitis (Pink Eye)

    MedlinePlus

    ... can be embedded on web pages. Conjunctivitis (Pink Eye) One-Page Overview Pink, itchy eyes? Conjunctivitis – or ... yourself from getting and spreading pink eye . Pink Eye: What To Do Discusses causes and treatment, when ...

  10. Eye Injuries at Home

    MedlinePlus

    ... Ophthalmologist Patient Stories Español Eye Health / Tips & Prevention Eye Injuries Sections Preventing Eye Injuries Recognizing and Treating ... Numbers — Infographic Five Steps to Safer Champagne Celebrations Eye Injuries at Home Reviewed by: Brenda Pagan-Duran ...

  11. Eye muscle repair - discharge

    MedlinePlus

    ... Lazy eye repair - discharge; Strabismus repair - discharge; Extraocular muscle surgery - discharge ... You or your child had eye muscle repair surgery to correct eye muscle ... term for crossed eyes is strabismus. Children most often ...

  12. Why Do Eyes Water?

    MedlinePlus

    ... Happens in the Operating Room? Why Do Eyes Water? KidsHealth > For Kids > Why Do Eyes Water? A ... out of your nose. continue Why Do Eyes Water? Eyes water for lots of different reasons besides ...

  13. Why Do Eyes Water?

    MedlinePlus

    ... Lifesaver Kids Talk About: Coaches Why Do Eyes Water? KidsHealth > For Kids > Why Do Eyes Water? Print ... out of your nose. continue Why Do Eyes Water? Eyes water for lots of different reasons besides ...

  14. Eye Movement Disorders

    MedlinePlus

    ... t work properly. There are many kinds of eye movement disorders. Two common ones are Strabismus - a disorder ... of the eyes, sometimes called "dancing eyes" Some eye movement disorders are present at birth. Others develop over ...

  15. [The dangers of blue light: True story!].

    PubMed

    Renard, G; Leid, J

    2016-05-01

    The dangers of the blue light are the object of numerous publications, for both the scientific community and the general public. The new prolific development of light sources emitting potentially toxic blue light (415-455nm) ranges from LED (Light Emitting Diodes) lamps for interior lighting to television screens, computers, digital tablets and smartphones using OLED (Organic Light Emitting Diode) or AMOLED (Active-Matrix Organic Light Emitting Diode) technology. First we will review some technical terms and the main characteristics of light perceived by the human eye. Then we will discuss scientific proof of the toxicity of blue light to the eye, which may cause cataract or macular degeneration. Analysis of the light spectra of several light sources, from natural light to LED lamps, will allow us to specify even better the dangers related to each light source. LED lamps, whether used as components for interior lighting or screens, are of concern if they are used for extended viewing times and at short distance. While we can protect ourselves from natural blue light by wearing colored glasses which filter out, on both front and back surfaces, the toxic wavelengths, it is more difficult to protect oneself from LED lamps in internal lighting, the use of which should be restricted to "white warmth" lamps (2700K). As far as OLED or AMOLED screens are concerned, the only effective protection consists of using them occasionally and only for a short period of time. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  16. Si-based blue light emitting diode

    NASA Astrophysics Data System (ADS)

    Namavar, Fereydoon

    1994-05-01

    Phase 1 results demonstrated for the first time a strong, stable blue-green emission from C-implanted red-emitting porous silicon. The objective of Phase 1 was to obtain blue-green emission from porous Si structure either by increasing the bandgap of the substrate by growth of Si-C random alloys prior to forming nanostructures with quantum confined properties, or by increasing the confinement energy of red-emitting Si nanostructures. Porous structures fabricated from group 4 alloys epitaxially grown by chemical vapor deposition (CVD) resulted in an enhancement in light emission of about one order of magnitude after incorporation of a very small amount of carbon in the epitaxial grown films. Strong blue-green light emission was observed by the naked eye from C-implanted and annealed porous Si. Using AlGaAs as a reference, we observed that the intensity of blue-green emission was one order of magnitude higher than that of the original red-emitting porous Si. Catholuminescence measurements of our samples performed at the University of Colorado show blue emission at 1.80 eV and 2.80 eV. Fourier transform infrared (FTIR) spectra of a blue-green emitting porous structure shows an IR absorption line identical to that of SiC and electron diffraction studies clearly show reflections corresponding to beta-SiC. Phase 1 results indicate that blue-green light is from SiC nanostructures with quantum confined properties. This material may be used to fabricate blue light-emitting Si-based devices which can be easily integrated into Si technology.

  17. Is eye color a predictor of noise-induced hearing loss?

    PubMed

    Carlin, M F; McCroskey, R L

    1980-01-01

    This study investigated the hypothesis that eye color is related to permanent threshold shift. Hearing levels and eye color determinations (gray, blue, hazel, and brown) were obtained for 100 industrial employees. Discriminant function analyses were utilized to attempt to establish linear combinations of variables that would identify group membership (i.e., eye color) correctly. Linear combinations of variables were not effective in delineating group membership. Probabililty statistics were then utilized to evaluate the probability of the determined relationships. These results indicated predictive accuracy of 69% for blue-eyed workers and 59% for brown-eyed workers.

  18. Eye contricks

    PubMed Central

    Wade, Nicholas J

    2011-01-01

    Pictorial images are icons as well as eye-cons: they provide distillations of objects or ideas into simpler shapes. They create the impression of representing that which cannot be presented. Even at the level of the photograph, the links between icon and object are tenuous. The dimensions of depth and motion are missing from icons, and these alone introduce all manner of potential ambiguities. The history of art can be considered as exploring the missing link between icon and object. Eye-cons can also be illusions—tricks of vision so that what is seen does not necessarily correspond to what is physically presented. Pictorial images can be spatialised or stylised; spatialised images generally share some of the projective characteristics of the object represented. Written words are also icons, but they do not resemble the objects they represent—they are stylised or conventional. Icons as stylised words and spatialised images were set in delightful opposition by René Magritte in a series of pipe paintings, and this theme is here alluded to. Most of visual science is now concerned with icons—two-dimensional displays on computer monitors. Is vision now the science of eye-cons? PMID:23145240

  19. Black Eye: First Aid

    MedlinePlus

    First aid Black eye: First aid Black eye: First aid By Mayo Clinic Staff A black eye is caused by bleeding under the skin around the eye. Most injuries that cause a black eye aren't serious. But a black eye ...

  20. 244. Humpback Rocks Visitor Center. View of the Mountain Farm ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    244. Humpback Rocks Visitor Center. View of the Mountain Farm Exhibit located on the general site of the Old Charlie Carter Farm. To the left is the CA. 1890 single-crib log William Lawless Billy Ramsey cabin moved from below Robinson Gap and to the right is a chicken house relocated from the John C. Clarke place about a mile north of Irish Gap. View faces north. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  1. 4. Humpback Rocks Visitor Center. View of the Mountain Farm ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Humpback Rocks Visitor Center. View of the Mountain Farm Exhibit located on the general site of the Old Charlie Carter Farm. To the left is the CA. 1890 single-crib log William Lawless Billy Ramsey house moved from below Robinson gap and to the right is a chicken house relocated from the John C. Clark Place about a mile north of Irish Gap. View faces north. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  2. 88. Groundhog Mountain. View of the log fire lookout constructed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    88. Groundhog Mountain. View of the log fire lookout constructed by the Virginia State Forest service in the summer of 1942. A buck or Yankee fence crosses the foreground with a snake fence in the background. Civilian public service employees began erecting the rail fences in April 1939. Looking north-northeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  3. Mountains: An Overview.

    ERIC Educational Resources Information Center

    Byers, Alton; Gilligan, Nancy; Golston, Syd; Linville, Rex

    1999-01-01

    Introduces the lessons from "Mountain: A Global Resource" that were developed by the National Council for the Social Studies (NCSS) and The Mountain Institute for use by NCSS members and their students. Provides an overview that introduces the mountains, mountain cultures, historical perceptions, and the geographical importance of…

  4. Evaluating the blue-light hazard from solid state lighting.

    PubMed

    Bullough, John D; Bierman, Andrew; Rea, Mark S

    2017-10-06

    New light sources including light-emitting diodes (LEDs) have elicited questions about retinal damage, including the blue-light hazard. Some organizations have recommended avoiding using LEDs with correlated color temperatures exceeding 3000 K, since they tend to produce greater short-wavelength energy. This article provides quantitative comparisons among light sources and use cases as they affect the blue-light hazard. The spectral radiant power characteristics of incandescent, fluorescent, LED and daylight sources were evaluated in terms of blue-light hazard using standard procedures for phakic, aphakic and pseudophakic eyes. Under most use cases, LEDs do not exhibit greater risk for the blue-light hazard than other sources (e.g., incandescent). Because they generally produce little to no ultraviolet energy, LEDs often present less risk to aphakic eyes. LEDs present no special concerns for the blue-light hazard over some other common sources in typical use cases because photophobic responses limit exposure to bright sources. Where photophobic responses might not occur (e.g., eye surgery patients or premature infants) or where individuals suppress these responses (e.g., stage actors), caution is necessary. Evidence remains inconsistent regarding the risk of human retinal damage from long-term exposures to light insufficient to reach acute blue-light hazard thresholds.

  5. Sensitive blood-retinal barrier breakdown quantitation using Evans blue.

    PubMed

    Xu, Q; Qaum, T; Adamis, A P

    2001-03-01

    This study investigated whether a nonradioactive dye, Evans blue, can be adapted as a safe alternative to the isotope-dilution method for quantitating blood-retinal barrier breakdown. Blood-retinal barrier breakdown was induced in rats with vascular endothelial growth factor (VEGF) or through the induction of diabetes. After allowing Evans blue to circulate in the vasculature, the dye was cleared from the bloodstream with saline, citrate, or citrate-buffered paraformaldehyde, and the efficacies of the perfusion solutions were compared. Extravasated dye was detected at 620 nm and was normalized against the time-averaged Evans blue plasma concentration, the circulation time, and also against wet and dry retina weights. Evans blue leakage from retinas treated with VEGF was 4.0-fold higher than that of contralateral untreated eyes (n = 6 rats, P: < 0.05). Retinal Evans blue leakage of eyes from 1-week diabetic animals (n = 11 retinas) was 1.7-fold higher (P: < 0.05) than that of nondiabetic controls (n = 10 retinas). Intra-animal, inter-retina weights showed significantly less variability (P: < 0.05) with the use of dry weights (11.2%, n = 74 retina pairs) than with wet weights (20.5%, n = 93 retina pairs). The Evans blue dye technique can be modified to be as sensitive and quantitative as the isotope-dilution method for measuring blood-retinal barrier breakdown. The advantages of the Evans blue technique are its safety, relative simplicity, and economy.

  6. Six-Year Incidence of Age-Related Macular Degeneration in Asian Malays: The Singapore Malay Eye Study.

    PubMed

    Cheung, Chui Ming Gemmy; Ong, Peng Guan; Neelam, Kumari; Tan, Pok Chien; Shi, Yuan; Mitchell, Paul; Wang, Jie Jin; Sabanayagam, Charumathi; Cheng, Ching-Yu; Wong, Tien Yin

    2017-09-01

    To determine the 6-year incidence of early and late age-related macular degeneration (AMD) in a Singaporean Malay population and to validate the Age-Related Eye Disease Study (AREDS) simplified severity scale in Asians. Prospective, population cohort study. The Singapore Malay Eye Study baseline participants (age, ≥40 years; 2006-2008) were followed up in 2011 through 2013, and 1901 of 3280 of eligible participants (72.1%) took part. Fundus photographs were graded using the Wisconsin AMD grading system. Incidence of early and late AMD. Gradable fundus photographs were available for 1809 participants who attended both baseline and 6-year follow-up examinations. The age-standardized incidences of early and late AMD were 5.89% (95% confidence interval [CI], 4.81-7.16) and 0.76% (95% CI, 0.42-1.29), respectively. The 5-year age-standardized incidence of early AMD (calculated based on the 6-year incidence) was lower in our population (5.58%; 95% CI, 4.43-7.01) compared with the Beaver Dam Eye Study population (8.19%). The incidence of late AMD in our population was similar to that of the Beaver Dam Eye Study population (0.98% [95% CI, 0.49-1.86] vs. 0.91%), the Blue Mountains Eye Study population (1.10% [95% CI, 0.52-9.56] vs. 1.10%), and the Hisayama Study population (1.09% [95% CI, 0.54-4.25] vs. 0.84%). The incidence of late AMD increased markedly with increasing baseline AREDS score (step 0, 0.23%; step 4, 9.09%). This study documented the incidence of early and late AMD in a Malay population. The AREDS simplified severity scale is useful in predicting the risk of late AMD development in Asians. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  7. Billie's eyes.

    PubMed

    Dunning, S E

    1993-03-01

    The author, a nurse, is personally opposed to abortion; however, her earlier encounter with a victim of an illegal abortion has prevented her from joining campaigns to reinstate bans on abortion rights. The woman, "Billie," presented to an inner-city Chicago hospital in 1970 with hemorrhaging. She had delayed going for treatment because she feared being imprisoned for having obtained an abortion. She rapidly entered septic shock, with hypotension, confusion, and hallucinations. Physicians removed her infected uterus and ovaries. Subsequent kidney failure necessitated the transfer of this young woman to another hospital where she could receive dialysis. The author was unable to obtain follow-up information on whether Billie survived. She remains haunted by the memory of Billie's wide, frightened eyes as she was placed in the ambulance. It is this memory, and the knowledge that desperate women like Billie will find someone, somewhere to perform an illegal abortion, that is behind the author's reluctant support for the right to choose.

  8. Blue Ocean Thinking

    ERIC Educational Resources Information Center

    Orem, Donna

    2016-01-01

    This article describes a concept called the "blue ocean thinking strategy," developed by W. Chan Kim and Renée Mauborgne, professors at INSEAD, an international graduate school of business in France. The "blue ocean" thinking strategy considers opportunities to create new markets for services, rather than focusing solely on…

  9. Introducing the Blues.

    ERIC Educational Resources Information Center

    Sinclair, Bryan

    2000-01-01

    Discusses the history of the blues and presents a list of resources that are designed to introduce the blues, both as a feeling and as an influential part of American music and culture. Includes picture books and nonfiction for young readers, nonfiction for older readers, Web sites, and compact disks. (LRW)

  10. Blue Ocean Thinking

    ERIC Educational Resources Information Center

    Orem, Donna

    2016-01-01

    This article describes a concept called the "blue ocean thinking strategy," developed by W. Chan Kim and Renée Mauborgne, professors at INSEAD, an international graduate school of business in France. The "blue ocean" thinking strategy considers opportunities to create new markets for services, rather than focusing solely on…

  11. Templated blue phases.

    PubMed

    Ravnik, Miha; Fukuda, Jun-ichi

    2015-11-21

    Cholesteric blue phases of a chiral liquid crystal are interesting examples of self-organised three-dimensional nanostructures formed by soft matter. Recently it was demonstrated that a polymer matrix introduced by photopolymerization inside a bulk blue phase not only stabilises the host blue phase significantly, but also serves as a template for blue phase ordering. We show with numerical modelling that the transfer of the orientational order of the blue phase to the surfaces of the polymer matrix, together with the resulting surface anchoring, can account for the templating behaviour of the polymer matrix inducing the blue phase ordering of an achiral nematic liquid crystal. Furthermore, tailoring the anchoring conditions of the polymer matrix surfaces can bring about orientational ordering different from those of bulk blue phases, including an intertwined complex of the polymer matrix and topological line defects of orientational order. Optical Kerr response of templated blue phases is explored, finding large Kerr constants in the range of K = 2-10 × 10(-9) m V(-2) and notable dependence on the surface anchoring strength. More generally, the presented numerical approach is aimed to clarify the role and actions of templating polymer matrices in complex chiral nematic fluids, and further to help design novel template-based materials from chiral liquid crystals.

  12. Blue Willow Story Plates

    ERIC Educational Resources Information Center

    Fontes, Kris

    2009-01-01

    In the December 1997 issue of "SchoolArts" is a lesson titled "Blue Willow Story Plates" by Susan Striker. In this article, the author shares how she used this lesson with her middle-school students many times over the years. Here, she describes a Blue Willow plate painting project that her students made.

  13. Blue Willow Story Plates

    ERIC Educational Resources Information Center

    Fontes, Kris

    2009-01-01

    In the December 1997 issue of "SchoolArts" is a lesson titled "Blue Willow Story Plates" by Susan Striker. In this article, the author shares how she used this lesson with her middle-school students many times over the years. Here, she describes a Blue Willow plate painting project that her students made.

  14. List 47: blue honeysuckle

    USDA-ARS?s Scientific Manuscript database

    This summary presents the descriptions of a newly released blue honeysuckle (Lonicera cerulea L.) cultivar for the List of New Fruit and Nut Cultivars. This blue honeysuckle cultivar was released in Canada in 2012 and has pending Plant Breeder’s Rights Certification with Agriculture Canada. The cult...

  15. Molecular evidence for the subspecific differentiation of blue sheep (Pseudois nayaur) and polyphyletic origin of dwarf blue sheep (Pseudois schaeferi).

    PubMed

    Tan, Shuai; Zou, Dandan; Tang, Lei; Wang, Gaochao; Peng, Quekun; Zeng, Bo; Zhang, Chen; Zou, Fangdong

    2012-06-01

    Blue sheep (Pseudois nayaur), a Central Asian ungulate with restricted geographic distribution, exhibits unclear variation in morphology and phylogeographic structure. The composition of species and subspecies in the genus Pseudois is controversial, particularly with respect to the taxonomic designation of geographically restricted populations. Here, 26 specimens including 5 dwarf blue sheep (Pseudois schaeferi), which were collected from a broad geographic region in China, were analyzed for 2 mitochondrial DNA fragments (cytochrome b and control region sequences). In a pattern consistent with geographically defined subspecies, we found three deeply divergent mitochondrial lineages restricted to different geographic regions. The currently designated two subspecies of blue sheep, Pseudois nayaur nayaur and Pseudois nayaur szechuanensis, were recognized in the phylogenetic trees. In addition, the Helan Mountain population showed distinct genetic characteristics from other geographic populations, and thus should be classified as a new subspecies. In contrast, dwarf blue sheep clustered closely with some blue sheep from Sichuan Province in the phylogenetic trees. Therefore, dwarf blue sheep appear to be a subset of Pseudois nayaur szechuanensis. After considering both population genetic information and molecular clock analysis, we obtained some relevant molecular phylogeographic information concerning the historical biogeography of blue sheep. These results also indicate that western Sichuan was a potential refugium for blue sheep during the Quaternary period.

  16. After Stroke, 'Blue' Light May Help Beat the Blues

    MedlinePlus

    ... Light May Help Beat the Blues Akin to sunlight, it could ward off depression during rehab, study ... facility used "blue" light in its lighting system. Sunlight is humans' largest source of blue-spectrum light, ...

  17. The Colossal Cosmic Eye

    NASA Astrophysics Data System (ADS)

    2005-09-01

    Eighty-five million years ago on small planet Earth, dinosaurs ruled, ignorant of their soon-to-come demise in the great Jurassic extinction, while mammals were still small and shy creatures. The southern Andes of Bolivia, Chile, and Argentina were not yet formed and South America was still an island continent. Eighty-five million years ago, our Sun and its solar system was 60,000 light years away from where it now stands [1]. Eighty-five million years ago, in another corner of the Universe, light left the beautiful spiral galaxy NGC 1350, for a journey across the universe. Part of this light was recorded at the beginning of the year 2000 AD by ESO's Very Large Telescope, located on the 2,600m high Cerro Paranal in the Chilean Andes on planet Earth. Astronomers classify NGC 1350 as an Sa(r) type galaxy, meaning it is a spiral with large central regions. In fact, NGC 1350 lies at the border between the broken-ring spiral type and a grand design spiral with two major outer arms. It is about 130,000 light-years across and, hence, is slightly larger than our Milky Way. The rather faint and graceful outer arms originate at the inner main ring and can be traced for almost half a circle when they each meet the opposite arm, giving the impression of completing a second outer ring, the "eye". The arms are given a blue tint as a result of the presence of very young and massive stars. The amount of dust, seen as small fragmented dust spirals in the central part of the galaxy and producing a fine tapestry that bear resemblance with blood vessels in the eye, is also a signature of the formation of stars.

  18. From blue jeans to blue genes.

    PubMed

    Boon, Laurence M; Vikkula, Miikka

    2009-03-01

    Cutaneous venous anomalies are common. They are blue and vary in size, number, and location and account for most consultations at specialized interdisciplinary clinics for vascular anomalies. Venous lesions are clinically important because they cause pain, dysfunction, destruction of adjacent tissues, and esthetic concern. Only resection and sclerotherapy are helpful, although not always curative. Understanding etiopathogenesis could help design animal models and develop novel therapeutic approaches. John B. Mulliken, MD, envisioned a project to uncover the genetic basis of an inherited form of venous malformation in a large New England family. Recruitment of 2 young fellows resulted in a collaborative project that unraveled the searched-for gene and its mutation. This was an opening for a new era in vascular anomalies. Two blue genes' mutations were discovered, which account for most, if not all, of the inherited forms of venous anomalies, but other genes as well, for rheologically diverse lesions. Differential diagnosis and management has improved, and animal models are being made. This was achieved through the help of Dr Mulliken, who inspired 2 young investigators in blue jeans to find 2 blue genes.

  19. FROM BLUE JEANS TO BLUE GENES

    PubMed Central

    Boon, Laurence M.; Vikkula, Miikka

    2010-01-01

    Cutaneous venous anomalies are common. They are blue in color and vary in size, number and location, and account for the majority of consultations at specialized interdisciplinary clinics for vascular anomalies. Venous lesions are clinically important as they cause pain, dysfunction, destruction of adjacent tissues and esthetic concern. Only resection and sclerotherapy are helpful, although not always curative. Understanding etiopathogenesis could help design animal models and develop novel therapeutic approaches. Dr Mulliken envisioned a project to uncover the genetic basis of an inherited form of venous malformation in a large New England family. Recruitment of two young fellows resulted in a collaborative project that unraveled the searched-for-gene and its mutation. This was an opening for a new era in the field of vascular anomalies. Two blue genes’ mutations were discovered, which account for the majority, if not all, of the inherited forms of venous anomalies, but other genes as well, for rheologically diverse lesions. Differential diagnosis and management has improved, and animal models are being made. This was achieved thanks to Dr Mulliken, who inspired two young investigators in blue jeans to find two blue genes. PMID:19190503

  20. Rocky Mountain spotted fever

    MedlinePlus

    ... page: //medlineplus.gov/ency/article/000654.htm Rocky Mountain spotted fever To use the sharing features on this page, please enable JavaScript. Rocky Mountain spotted fever is a disease caused by a ...

  1. Eye Injuries (For Parents)

    MedlinePlus

    ... Old Feeding Your 1- to 2-Year-Old Eye Injuries KidsHealth > For Parents > Eye Injuries Print A ... sand, dirt, and other foreign bodies on the eye surface) Wash your hands thoroughly before touching the ...

  2. Diabetes - eye care

    MedlinePlus

    ... page: //medlineplus.gov/ency/patientinstructions/000078.htm Diabetes - eye care To use the sharing features on this ... prevent them from getting worse. You Need Regular eye Exams Every year, you should have an eye ...

  3. Eye muscle repair - slideshow

    MedlinePlus

    ... page: //medlineplus.gov/ency/presentations/100062.htm Eye muscle repair - series—Normal anatomy To use the sharing ... the eyeball to the eye socket. The external muscles of the eye are found behind the conjunctiva. ...

  4. Eye Cosmetic Safety

    MedlinePlus

    ... when they are new. FDA has an Import Alert in effect for cosmetics -- including eye cosmetics -- contaminated ... in the area of the eye. An import alert for cosmetics containing illegal colors lists several eye ...

  5. Dilating Eye Drops

    MedlinePlus

    ... sometimes used to treat eye diseases, such as amblyopia and inflammation. How long do dilating drops last? ... used to treat certain eye diseases, such as amblyopia and inflammation in the eye. These therapeutic dilating ...

  6. The Genetic Overlap Between Hair and Eye Color.

    PubMed

    Lin, Bochao D; Willemsen, Gonneke; Abdellaoui, Abdel; Bartels, Meike; Ehli, Erik A; Davies, Gareth E; Boomsma, Dorret I; Hottenga, Jouke J

    2016-12-01

    We identified the genetic variants for eye color by Genome-Wide Association Study (GWAS) in a Dutch Caucasian family-based population sample and examined the genetic correlation between hair and eye color using data from unrelated participants from the Netherlands Twin Register. With the Genome-wide Complex Trait Analysis software package, we found strong genetic correlations between various combinations of hair and eye colors. The strongest positive correlations were found for blue eyes with blond hair (0.87) and brown eyes with dark hair (0.71), whereas blue eyes with dark hair and brown eyes with blond hair showed the strongest negative correlations (-0.64 and -0.94, respectively). Red hair with green/hazel eyes showed the weakest correlation (-0.14). All analyses were corrected for age and sex, and we explored the effects of correcting for principal components (PCs) that represent ancestry and describe the genetic stratification of the Netherlands. When including the first three PCs as covariates, the genetic correlations between the phenotypes disappeared. This is not unexpected since hair and eye colors strongly indicate the ancestry of an individual. This makes it difficult to separate the effects of population stratification and the true genetic effects of variants on these particular phenotypes.

  7. Eyeing Ganymede

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Jupiter casts a baleful eye toward the moon Ganymede in this enhanced-contrast image from NASA's Cassini spacecraft.

    Jupiter's 'eye', the Great Red Spot, was captured just before disappearing around the eastern edge of the planet. The furrowed eyebrow above and to the left of the spot is a turbulent wake region caused by westward flow that has been deflected to the north and around the Red Spot. The smallest features visible are about 240 kilometers (150 miles) across.

    Within the band south of the Red Spot are a trio of white ovals, high pressure counterclockwise-rotating regions that are dynamically similar to the Red Spot. The dark filamentary features interspersed between white ovals are probably cyclonic circulations and, unlike the ovals, are rotating clockwise.

    Jupiter's equatorial zone stretching across the planet north of the Spot appears bright white, with gigantic plume clouds spreading out from the equator both to the northeast and to the southeast in a chevron pattern. This zone looks distinctly different than it did during the Voyager flyby 21 years ago. Then, its color was predominantly brown and the only white plumes conspicuous against the darker material beneath them were oriented southwest-to-northeast.

    Ganymede is Jupiter's largest moon, about 50 percent larger than our own Moon and larger than the planet Mercury. The visible details in this image are different geological terrains. Dark areas tend to be older and heavily cratered; brighter areas are younger and less cratered. Cassini images of Ganymede and Jupiter's other large moons taken near closest approach on Dec. 30 will have resolutions about four times better than that seen here.

    This image is a color composite of ones taken with different filters by Cassini's narrow-angle camera on Nov. 18, 2000, processed to enhance contrast. Cassini is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. The Jet Propulsion Laboratory, a division of

  8. Lesson 2: Sacred Mountains.

    ERIC Educational Resources Information Center

    Byers, Alton; Gilligan, Nancy; Golston, Syd; Linville, Rex

    1999-01-01

    Presents a lesson in which the students are divided into four Mountain Study Teams in order to examine a sacred mountain. Explains that the students in each group assume a particular role, such as an historian or scientist. Provides a profile on the four mountains and a definition of the seven student roles. (CMK)

  9. Mountains of Titan

    NASA Image and Video Library

    2012-12-14

    This map of Saturn moon Titan identifies the locations of mountains named by the International Astronomical Union. By convention, mountains on Titan are named for mountains from Middle-earth, the fictional setting in fantasy novels by J.R.R. Tolkien.

  10. Blue ocean strategy.

    PubMed

    Kim, W Chan; Mauborgne, Renée

    2004-10-01

    Despite a long-term decline in the circus industry, Cirque du Soleil profitably increased revenue 22-fold over the last ten years by reinventing the circus. Rather than competing within the confines of the existing industry or trying to steal customers from rivals, Cirque developed uncontested market space that made the competition irrelevant. Cirque created what the authors call a blue ocean, a previously unknown market space. In blue oceans, demand is created rather than fought over. There is ample opportunity for growth that is both profitable and rapid. In red oceans--that is, in all the industries already existing--companies compete by grabbing for a greater share of limited demand. As the market space gets more crowded, prospects for profits and growth decline. Products turn into commodities, and increasing competition turns the water bloody. There are two ways to create blue oceans. One is to launch completely new industries, as eBay did with online auctions. But it's much more common for a blue ocean to be created from within a red ocean when a company expands the boundaries of an existing industry. In studying more than 150 blue ocean creations in over 30 industries, the authors observed that the traditional units of strategic analysis--company and industry--are of limited use in explaining how and why blue oceans are created. The most appropriate unit of analysis is the strategic move, the set of managerial actions and decisions involved in making a major market-creating business offering. Creating blue oceans builds brands. So powerful is blue ocean strategy, in fact, that a blue ocean strategic move can create brand equity that lasts for decades.

  11. New Lepidoptera records for the Blue Mountains of eastern Oregon.

    Treesearch

    David G. Grimble; Roy C. Beckwith; Paul C. Hammond

    1993-01-01

    Black-light trap collections in mixed-coniferous forests in eastern Oregon resulted in the identification of one Arctiidae, six Noctuidae, and one Geometridae species not previously known to occur in Oregon. The ranges of 18 other species of Noctuidae, known previously in Oregon from only the Cascade and Coast Ranges, were extended to northeastern Oregon.

  12. Prediction of eye color in the Slovenian population using the IrisPlex SNPs.

    PubMed

    Kastelic, Vanja; Pośpiech, Ewelina; Draus-Barini, Jolanta; Branicki, Wojciech; Drobnič, Katja

    2013-08-01

    To evaluate the accuracy of eye color prediction based on six IrisPlex single nucleotide polymorphisms (SNP) in a Slovenian population sample. Six IrisPlex predictor SNPs (HERC2 - rs12913832, OCA2 - rs1800407, SLC45A2 - rs16891982 and TYR - rs1393350, SLC24A4 - rs12896399, and IRF4 - rs12203592) of 105 individuals were analyzed using single base extension approach and SNaPshot chemistry. The IrisPlex multinomial regression prediction model was used to infer eye color probabilities. The accuracy of the IrisPlex was assessed through the calculation of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the area under the receiver characteristic operating curves (AUC). Blue eye color was observed in 44.7%, brown in 29.6%, and intermediate in 25.7% participants. Prediction accuracy expressed by the AUC was 0.966 for blue, 0.913 for brown, and 0.796 for intermediate eye color. Sensitivity was 93.6% for blue, 58.1% for brown, and 0% for intermediate eye color. Specificity was 93.1% for blue, 89.2% for brown, and 100% for intermediate eye color. PPV was 91.7% for blue and 69.2% for brown color. NPV was 94.7% for blue and 83.5% for brown eye color. These values indicate prediction accuracy comparable to that established in other studies. Blue and brown eye color can be reliably predicted from DNA samples using only six polymorphisms, while intermediate eye color defies prediction, indicating that more research is needed to genetically predict the whole variation of eye color in humans.

  13. 76 FR 5147 - Blue Heron Hydro LLC; Notice of Application Accepted for Filing and Soliciting Motions To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... Energy Regulatory Commission Blue Heron Hydro LLC; Notice of Application Accepted for Filing and... Heron Hydro LLC. e. Name of Project: Ball Mountain Dam Hydroelectric Project. f. Location: U.S. Army..., Blue Heron Hydro LLC, 113 Bartlett Road, Plainfield, Vermont 05667. (802) 454 1874. i. FERC Contact:...

  14. Epikeratoplasty for keratoglobus associated with blue sclera.

    PubMed

    Cameron, J A; Cotter, J B; Risco, J M; Alvarez, H

    1991-04-01

    Patients with keratoglobus and blue sclera as part of a generalized connective tissue disorder are at a high risk of developing corneal perforations either spontaneously or after mild trauma. Six patients (6 eyes) between the ages of 2 and 16 years of age (mean, 7.5 years) with keratoglobus, blue sclera, hypermobile joints, and consanguineous parents were treated by epikeratoplasty, using commercially prepared 12.5-mm lenticules. Surgery was performed for tectonic support and/or visual improvement and was successful in five of six patients with a follow-up period of 11 to 27 months (mean, 21 months). One lenticule was removed because the epithelium did not heal. Peripheral interface opacities occurred in three patients.

  15. Grove Mountains meteorite recovery and relevant data distribution service

    NASA Astrophysics Data System (ADS)

    Zhou, Chunxia; Ai, Songtao; Chen, Nengcheng; Wang, Zemin; E, Dongchen

    2011-11-01

    Meteorites are extremely valuable in providing clues about the origin, evolution, and composition of the Sun, the Moon, the Earth, other planets, and asteroids. Since the first discovery of a meteorite in Antarctica, more and more meteorite concentrations on bare ice stranding sites were discovered. Antarctica is identified as a prolific source of extraterrestrial materials. The Grove Mountains area, covered by ice, snow, and nunataks, is located in the Antarctic inland area. It is about 380 km away from the Chinese Zhongshan Antarctic Research Station in East Antarctica. Since 1998, 11,452 meteorites have been collected from the Grove Mountains by the Chinese National Antarctic Research Expedition (CHINARE). It is confirmed that the Grove Mountains area is a productive search area for meteorites in Antarctica. More and more meteorite recoveries led to the recognition that unique mechanisms relating to meteorite concentrations exist in Antarctica. Besides meteorite field collections, the extraction of blue ice based on satellite images, meteorite concentration mechanisms, and meteorite data distribution service are discussed in this paper. Wide distribution of blue ice indicates the enrichment of meteorites. Based on the different spectrum characteristics and coherence of snow, blue ice, and bare rocks, blue ice areas are extracted from optical images and coherence maps. According to meteorite field collections and optical images, moraines are also identified as meteorite concentration sites in the Grove Mountains area. The meteorite concentration theories should be further analyzed by taking into account ice-flow dynamics, mountains' blocking effect, katabatic wind and ice ablation, and others. Moreover, in order to strengthen the visualization and network sharing of the valuable meteorite data, desktop software based on ArcObjects and web software based on ArcIMS are developed within this study. The desktop software also enables further analysis of the meteorite

  16. Anti-Atlas Mountains, Morocco

    NASA Image and Video Library

    2003-01-08

    The Anti-Atlas Mountains of Morocco formed as a result of the collision of the African and Eurasian tectonic plates about 80 million years ago. This collision destroyed the Tethys Ocean; the limestone, sandstone, claystone, and gypsum layers that formed the ocean bed were folded and crumpled to create the Atlas and Anti-Atlas Mountains. In this ASTER image, short wavelength infrared bands are combined to dramatically highlight the different rock types, and illustrate the complex folding. The yellowish, orange and green areas are limestones, sandstones and gypsum; the dark blue and green areas are underlying granitic rocks. The ability to map geology using ASTER data is enhanced by the multiple short wavelength infrared bands, that are sensitive to differences in rock mineralogy. This image was acquired on June 13, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet. http://photojournal.jpl.nasa.gov/catalog/PIA03893

  17. Mongolian blue spots

    MedlinePlus

    ... bruises. This can raise a question about possible child abuse. It is important to recognize that Mongolian blue ... Elsevier Saunders; 2011:chap 11. Read More Benign Child abuse - physical Rashes Review Date 4/14/2015 Updated ...

  18. Blue Ribbon Panel Report

    Cancer.gov

    An NCI Cancer Currents blog by the NCI acting director thanking the cancer community for contributing to the Cancer Moonshot Blue Ribbon Panel report, which was presented to the National Cancer Advisory Board on September 7.

  19. Blue-green algae

    MedlinePlus

    ... conditions, cancer, fatty liver disease, hepatitis C, and arsenic poisoning. Blue-green algae are applied inside the mouth ... people with insulin resistance due to HIV medication. Arsenic poisoning. Early research shows that taking 250 mg of ...

  20. Village Blue Webinar

    EPA Pesticide Factsheets

    The Village Blue research project provides real-time water quality monitoring data to the Baltimore community and increase public awareness about local water quality in Baltimore Harbor and the Chesapeake Bay.

  1. Mongolian blue spots (image)

    MedlinePlus

    Mongolian blue spots are flat bluish- to bluish-gray skin markings commonly appearing at birth or shortly ... back and also can appear on the shoulders. Mongolian spots are benign and are not associated with ...

  2. Eating for Your Eyes

    ERIC Educational Resources Information Center

    Stastny, Sherri Nordstrom; Garden-Robinson, Julie

    2011-01-01

    An educational program targeting older adults was developed to increase knowledge regarding nutrition and eye health. With age, the chance for eye disease increases, so prevention is critical. The Eating for Your Eyes program has promoted behavior changes regarding eye health among the participants. This program is easily replicated and use is…

  3. Eating for Your Eyes

    ERIC Educational Resources Information Center

    Stastny, Sherri Nordstrom; Garden-Robinson, Julie

    2011-01-01

    An educational program targeting older adults was developed to increase knowledge regarding nutrition and eye health. With age, the chance for eye disease increases, so prevention is critical. The Eating for Your Eyes program has promoted behavior changes regarding eye health among the participants. This program is easily replicated and use is…

  4. Eye Injuries (For Parents)

    MedlinePlus

    ... the eye nausea or vomiting after an eye injury Think Prevention! Kids who play sports should wear protective goggles or unbreakable glasses as needed. Keep chemicals and other potentially dangerous objects out of the reach of children. Reviewed by: Steven Dowshen, ... (Conjunctivitis) Eyes Corneal Abrasions Styes Activity: Eyes ...

  5. Eye Injuries in Sports

    MedlinePlus

    ... and Fitness Sports Safety Eye Injuries in Sports Eye Injuries in Sports Exercise and FitnessPrevention and WellnessSports Safety Share Eye Injuries ... injury, detached retina, patient education, patient information, penetrating eye ... Exercise and Fitness, Prevention and Wellness, Sports Safety June ...

  6. Serotonin syndrome following methylene blue administration during cardiothoracic surgery.

    PubMed

    Smith, Christina J; Wang, Dorothy; Sgambelluri, Anna; Kramer, Robert S; Gagnon, David J

    2015-04-01

    Despite its favorable safety profile, there have been reports of methylene blue-induced encephalopathy and serotonin syndrome in patients undergoing parathyroidectomy. We report a case of serotonin syndrome following methylene blue administration in a cardiothoracic surgery patient. A 59-year-old woman taking preoperative venlafaxine and trazodone was given a single dose of 2 mg/kg methylene blue (167 mg) during a planned coronary artery bypass and mitral valve repair. Postoperatively, she was febrile to 38.7°C and developed full-body tremors, rhythmic twitching of the perioral muscles, slow conjugate roving eye movements, and spontaneous movements of the upper extremities. Electroencephalography revealed generalized diffuse slowing consistent with toxic encephalopathy, and a computed tomography scan showed no acute process. The patient's symptoms were most consistent with a methylene blue-induced serotonin syndrome. Her motor symptoms resolved within 48 hours and she was eventually discharged home. Only 2 cases of methylene blue-induced serotonin syndrome during cardiothoracic surgery have been described in the literature, with this report representing the third case. Methylene blue and its metabolite, azure B, are potent, reversible inhibitors of monoamine oxidase A which is responsible for serotonin metabolism. Concomitant administration of methylene blue with serotonin-modulating agents may precipitate serotonin syndrome. © The Author(s) 2015.

  7. Atypical cellular blue nevus or malignant blue nevus?*

    PubMed Central

    Daltro, Luise Ribeiro; Yaegashi, Lygia Bertalha; Freitas, Rodrigo Abdalah; Fantini, Bruno de Carvalho; Souza, Cacilda da Silva

    2017-01-01

    Blue nevus is a benign melanocytic lesion whose most frequent variants are dendritic (common) blue nevus and cellular blue nevus. Atypical cellular blue nevus presents an intermediate histopathology between the typical and a rare variant of malignant blue nevus/melanoma arising in a cellular blue nevus. An 8-year-old child presented a pigmented lesion in the buttock since birth, but with progressive growth in the last two years. After surgical excision, histopathological examination revealed atypical cellular blue nevus. Presence of mitoses, ulceration, infiltration, cytological atypia or necrosis may occur in atypical cellular blue nevus, making it difficult to differentiate it from melanoma. The growth of blue nevus is unusual and considered of high-risk for malignancy, being an indicator for complete resection and periodic follow-up of these patients. PMID:28225968

  8. SNP model development for the prediction of eye colour in New Zealand.

    PubMed

    Allwood, Julia S; Harbison, Sallyann

    2013-07-01

    The ability to predict externally visible characteristics (EVCs) from DNA has appeal for use in forensic science, particularly where a forensic database match is not made and an eye witness account is unavailable. This technology has yet to be implemented in casework in New Zealand. The broad cultural diversity and likely population stratification within New Zealand dictates that any EVC predictions made using anonymous DNA must perform accurately in the absence of knowledge of the donor's ancestral background. Here we construct classification tree models with SNPs of known association with eye colour phenotypes in three categories, blue vs. non-blue, brown vs. non-brown and intermediate vs. non-intermediate. A set of nineteen SNPs from ten different known or suspected pigmentation genes were selected from the literature. A training dataset of 101 unrelated individuals from the New Zealand population and representing different ancestral backgrounds were used. We constructed four alternate models capable of predicting eye colour from the DNA genotypes of SNPs located within the HERC2, OCA2, TYR and SLC24A4 genes using probability calculation and classification trees. The final model selected for eye colour prediction exhibited high levels of accuracy for both blue (89%) and brown eye colour (94%). Models were further assessed with a test set of 25 'blind' samples where phenotype was unknown, with blue and brown eye colour predicted correctly where model thresholds were met. Classification trees offer an aesthetically simple and comprehendible model to predict blue and brown eye colour.

  9. Census of Blue Stars in SDSS DR8

    NASA Astrophysics Data System (ADS)

    Scibelli, Samantha; Newberg, Heidi Jo; Carlin, Jeffrey L.; Yanny, Brian

    2014-12-01

    We present a census of the 12,060 spectra of blue objects ((g - r)0 < -0.25) in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). As part of the data release, all of the spectra were cross-correlated with 48 template spectra of stars, galaxies, and QSOs to determine the best match. We compared the blue spectra by eye to the templates assigned in SDSS DR8. 10,856 of the objects matched their assigned template, 170 could not be classified due to low signal-to-noise ratio, and 1034 were given new classifications. We identify 7458 DA white dwarfs, 1145 DB white dwarfs, 273 rarer white dwarfs (including carbon, DZ, DQ, and magnetic), 294 subdwarf O stars, 648 subdwarf B stars, 679 blue horizontal branch stars, 1026 blue stragglers, 13 cataclysmic variables, 129 white dwarf-M dwarf binaries, 36 objects with spectra similar to DO white dwarfs, 179, quasi-stellar objects (QSOs), and 10 galaxies. We provide two tables of these objects, sample spectra that match the templates, figures showing all of the spectra that were grouped by eye, and diagnostic plots that show the positions, colors, apparent magnitudes, proper motions, etc., for each classification. Future surveys will be able to use templates similar to stars in each of the classes we identify to automatically classify blue stars, including rare types.

  10. CENSUS OF BLUE STARS IN SDSS DR8

    SciTech Connect

    Scibelli, Samantha; Newberg, Heidi Jo; Carlin, Jeffrey L.; Yanny, Brian

    2015-01-01

    We present a census of the 12,060 spectra of blue objects ((g – r){sub 0} < –0.25) in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). As part of the data release, all of the spectra were cross-correlated with 48 template spectra of stars, galaxies, and QSOs to determine the best match. We compared the blue spectra by eye to the templates assigned in SDSS DR8. 10,856 of the objects matched their assigned template, 170 could not be classified due to low signal-to-noise ratio, and 1034 were given new classifications. We identify 7458 DA white dwarfs, 1145 DB white dwarfs, 273 rarer white dwarfs (including carbon, DZ, DQ, and magnetic), 294 subdwarf O stars, 648 subdwarf B stars, 679 blue horizontal branch stars, 1026 blue stragglers, 13 cataclysmic variables, 129 white dwarf-M dwarf binaries, 36 objects with spectra similar to DO white dwarfs, 179, quasi-stellar objects (QSOs), and 10 galaxies. We provide two tables of these objects, sample spectra that match the templates, figures showing all of the spectra that were grouped by eye, and diagnostic plots that show the positions, colors, apparent magnitudes, proper motions, etc., for each classification. Future surveys will be able to use templates similar to stars in each of the classes we identify to automatically classify blue stars, including rare types.

  11. CENSUS OF BLUE STARS IN SDSS DR8

    SciTech Connect

    Scibelli, Samantha; Newberg, Heidi Jo; Carlin, Jeffrey L.; Yanny, Brian

    2014-12-02

    In this work, we present a census of the 12,060 spectra of blue objects ($(g-r)_0<-0.25$) in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). As part of the data release, all of the spectra were cross-correlated with 48 template spectra of stars, galaxies and QSOs to determine the best match. We compared the blue spectra by eye to the templates assigned in SDSS DR8. 10,856 of the objects matched their assigned template, 170 could not be classified due to low signal-to-noise (S/N), and 1034 were given new classifications. We identify 7458 DA white dwarfs, 1145 DB white dwarfs, 273 rarer white dwarfs (including carbon, DZ, DQ, and magnetic), 294 subdwarf O stars, 648 subdwarf B stars, 679 blue horizontal branch stars, 1026 blue stragglers, 13 cataclysmic variables, 129 white dwarf - M dwarf binaries, 36 objects with spectra similar to DO white dwarfs, 179 QSOs, and 10 galaxies. We provide two tables of these objects, sample spectra that match the templates, figures showing all of the spectra that were grouped by eye, and diagnostic plots that show the positions, colors, apparent magnitudes, proper motions, etc. for each classification. In conclusion, future surveys will be able to use templates similar to stars in each of the classes we identify to classify blue stars, including rare types, automatically.

  12. CENSUS OF BLUE STARS IN SDSS DR8

    DOE PAGES

    Scibelli, Samantha; Newberg, Heidi Jo; Carlin, Jeffrey L.; ...

    2014-12-02

    In this work, we present a census of the 12,060 spectra of blue objects (more » $$(g-r)_0<-0.25$$) in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). As part of the data release, all of the spectra were cross-correlated with 48 template spectra of stars, galaxies and QSOs to determine the best match. We compared the blue spectra by eye to the templates assigned in SDSS DR8. 10,856 of the objects matched their assigned template, 170 could not be classified due to low signal-to-noise (S/N), and 1034 were given new classifications. We identify 7458 DA white dwarfs, 1145 DB white dwarfs, 273 rarer white dwarfs (including carbon, DZ, DQ, and magnetic), 294 subdwarf O stars, 648 subdwarf B stars, 679 blue horizontal branch stars, 1026 blue stragglers, 13 cataclysmic variables, 129 white dwarf - M dwarf binaries, 36 objects with spectra similar to DO white dwarfs, 179 QSOs, and 10 galaxies. We provide two tables of these objects, sample spectra that match the templates, figures showing all of the spectra that were grouped by eye, and diagnostic plots that show the positions, colors, apparent magnitudes, proper motions, etc. for each classification. In conclusion, future surveys will be able to use templates similar to stars in each of the classes we identify to classify blue stars, including rare types, automatically.« less

  13. Getting Beyond Yucca Mountain - 12305

    SciTech Connect

    Halstead, Robert J.; Williams, James M.

    2012-07-01

    The U.S. Department of Energy has terminated the Yucca Mountain repository project. The U.S. Nuclear Regulatory Commission has indefinitely suspended the Yucca Mountain licensing proceeding. The presidentially-appointed Blue Ribbon Commission (BRC) on America's Nuclear Future is preparing a report, due in January 2012, to the Secretary of Energy on recommendations for a new national nuclear waste management and disposal program. The BRC Draft Report published in July 2011 provides a compelling critique of the past three decades failed efforts in the United States to site storage and disposal facilities for spent nuclear fuel (SNF) and high-level radioactive waste (HLW). However, the BRC Draft Report fails to provide detailed guidance on how to implement an alternative, successful approach to facility site selection. The comments submitted to the BRC by the State of Nevada Agency for Nuclear Projects provide useful details on how the US national nuclear waste program can get beyond the failed Yucca Mountain repository project. A detailed siting process, consisting of legislative elements, procedural elements, and 'rules' for volunteer sites, could meet the objectives of the BRC and the Western Governors Association (WGA), while promoting and protecting the interests of potential host states. The recent termination of the proposed Yucca Mountain repository provides both an opportunity and a need to re-examine the United States' nuclear waste management program. The BRC Draft Report published in July 2011 provides a compelling critique of the past three decades failed efforts in the United States to site storage and disposal facilities for SNF and HLW. It is anticipated that the BRC Final report in January 2012 will recommend a new general course of action, but there will likely continue to be a need for detailed guidance on how to implement an alternative, successful approach to facility site selection. Getting the nation's nuclear waste program back on track

  14. Functional eye movement disorders.

    PubMed

    Kaski, D; Bronstein, A M

    2017-01-01

    Functional (psychogenic) eye movement disorders are perhaps less established in the medical literature than other types of functional movement disorders. Patients may present with ocular symptoms (e.g., blurred vision or oscillopsia) or functional eye movements may be identified during the formal examination of the eyes in patients with other functional disorders. Convergence spasm is the most common functional eye movement disorder, but functional gaze limitation, functional eye oscillations (also termed "voluntary nystagmus"), and functional convergence paralysis may be underreported. This chapter reviews the different types of functional eye movement abnormalities and provides a practical framework for their diagnosis and management.

  15. The Cat's Eye Nebula

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This NASA Hubble Space Telescope image shows one of the most complex planetary nebulae ever seen, NGC 6543, nicknamed the 'Cat's Eye Nebula.' Hubble reveals surprisingly intricate structures including concentric gas shells, jets of high-speed gas and unusual shock-induced knots of gas. Estimated to be 1,000 years old, the nebula is a visual 'fossil record' of the dynamics and late evolution of a dying star. A preliminary interpretation suggests that the star might be a double-star system. The suspected companion star also might be responsible for a pair of high-speed jets of gas that lie at right angles to this equatorial ring. If the companion were pulling in material from a neighboring star, jets escaping along the companion's rotation axis could be produced. These jets would explain several puzzling features along the periphery of the gas lobes. Like a stream of water hitting a sand pile, the jets compress gas ahead of them, creating the 'curlicue' features and bright arcs near the outer edge of the lobes. The twin jets are now pointing in different directions than these features. This suggests the jets are wobbling, or precessing, and turning on and off episodically. This color picture, taken with the Wide Field Planetary Camera-2, is a composite of three images taken at different wavelengths. (red, hydrogen-alpha; blue, neutral oxygen, 6300 angstroms; green, ionized nitrogen, 6584 angstroms). The image was taken on September 18, 1994. NGC 6543 is 3,000 light- years away in the northern constellation Draco. The term planetary nebula is a misnomer; dying stars create these cocoons when they lose outer layers of gas. The process has nothing to do with planet formation, which is predicted to happen early in a star's life.

  16. Eye Colour and Reaction Time: An Opportunity for Critical Statistical Reasoning

    ERIC Educational Resources Information Center

    Watson, Jane

    2008-01-01

    This author was surprised to read a short article in "The Mercury" newspaper in Hobart about blue-eyed people being more intelligent and brown-eyed people having faster reaction times. Such an article invites immediate scepticism from the statistically literate. The lack of data in the article should lead the interested reader to a…

  17. Red krypton and blue-green argon laser diabetic panretinal photocoagulation.

    PubMed

    Blankenship, G W; Gerke, E; Batlle, J F

    1989-01-01

    Eyes with three or four diabetic retinopathy risk factors received laser panretinal photocoagulation with random selection of either blue-green argon (42 eyes) or red krypton (40 eyes) laser to determine if one laser was superior to the other. After 6 months, visual acuity preservation or improvement was obtained in 33 (79%) argon- and 34 (84%) krypton-treated eyes. Peripheral IV-4e visual field constriction of 7% occurred with argon and 10% with krypton. Vitreous hemorrhaging after treatment occurred in 1 argon- and in 6 krypton-treated eyes. Complete disc neovascular regression was obtained in 27 (67%) of 40 argon- and 19 (56%) of 34 krypton-treated eyes, with partial regression occurring in 8 (20%) argon- and 8 (24%) krypton-treated eyes. The two treatments produced essentially equal results.

  18. Human eye colour and HERC2, OCA2 and MATP.

    PubMed

    Mengel-From, Jonas; Børsting, Claus; Sanchez, Juan J; Eiberg, Hans; Morling, Niels

    2010-10-01

    Prediction of human eye colour by forensic genetic methods is of great value in certain crime investigations. Strong associations between blue/brown eye colour and the SNP loci rs1129038 and rs12913832 in the HERC2 gene were recently described. Weaker associations between eye colour and other genetic markers also exist. In 395 randomly selected Danes, we investigated the predictive values of various combinations of SNP alleles in the HERC2, OCA2 and MATP (SLC45A2) genes and compared the results to the eye colours as they were described by the individuals themselves. The highest predictive value of typing either the HERC2 SNPs rs1129038 and/or rs12913832 that are in strong linkage disequilibrium was observed when eye colour was divided into two groups, (1) blue, grey and green (light) and (2) brown and hazel (dark). Sequence variations in rs11636232 and rs7170852 in HERC2, rs1800407 in OCA2 and rs16891982 in MATP showed additional association with eye colours in addition to the effect of HERC2 rs1129038. Diplotype analysis of three sequence variations in HERC2 and one sequence variation in OCA2 showed the best discrimination between light and dark eye colours with a likelihood ratio of 29.3.

  19. Anticipatory Effects of Intonation: Eye Movements during Instructed Visual Search

    ERIC Educational Resources Information Center

    Ito, Kiwako; Speer, Shari R.

    2008-01-01

    Three eye-tracking experiments investigated the role of pitch accents during online discourse comprehension. Participants faced a grid with ornaments, and followed prerecorded instructions such as "Next, hang the blue ball" to decorate holiday trees. Experiment 1 demonstrated a processing advantage for felicitous as compared to infelicitous uses…

  20. Anticipatory Effects of Intonation: Eye Movements during Instructed Visual Search

    ERIC Educational Resources Information Center

    Ito, Kiwako; Speer, Shari R.

    2008-01-01

    Three eye-tracking experiments investigated the role of pitch accents during online discourse comprehension. Participants faced a grid with ornaments, and followed prerecorded instructions such as "Next, hang the blue ball" to decorate holiday trees. Experiment 1 demonstrated a processing advantage for felicitous as compared to infelicitous uses…

  1. Genetic analyses of the human eye colours using a novel objective method for eye colour classification.

    PubMed

    Andersen, Jeppe D; Johansen, Peter; Harder, Stine; Christoffersen, Susanne R; Delgado, Mikaela C; Henriksen, Sarah T; Nielsen, Mette M; Sørensen, Erik; Ullum, Henrik; Hansen, Thomas; Dahl, Anders L; Paulsen, Rasmus R; Børsting, Claus; Morling, Niels

    2013-09-01

    In this study, we present a new objective method for measuring the eye colour on a continuous scale that allows researchers to associate genetic markers with different shades of eye colour. With the use of the custom designed software Digital Iris Analysis Tool (DIAT), the iris was automatically identified and extracted from high resolution digital images. DIAT was made user friendly with a graphical user interface. The software counted the number of blue and brown pixels in the iris image and calculated a Pixel Index of the Eye (PIE-score) that described the eye colour quantitatively. The PIE-score ranged from -1 to 1 (brown to blue). The software eliminated the need for user based interpretation and qualitative eye colour categories. In 94% (570) of 605 analyzed eye images, the iris region was successfully extracted and a PIE-score was calculated. A very high correlation between the PIE-score and the human perception of eye colour was observed. The correlations between the PIE-scores and the six IrisPlex SNPs (HERC2 rs12913832, OCA2 rs1800407, SLC24A4 rs12896399, TYR rs1393350, SLC45A2 rs16891982 and IRF4 rs12203592) were analyzed in 570 individuals. Significant differences (p<10(-6)) in the PIE-scores of the individuals typed as HERC2 rs12913832 G (PIE=0.99) and rs12913832 GA (PIE=-0.71) or A (PIE=-0.87) were observed. We adjusted for the effect of HERC2 rs12913832 and showed that the quantitative PIE-scores were significantly associated with SNPs with minor effects (OCA2 rs1800407, SLC24A4 rs12896399 and TYR rs1393350) on the eye colour. We evaluated the two published prediction models for eye colour (IrisPlex [1] and Snipper[2]) and compared the predictions with the PIE-scores. We found good concordance with the prediction from individuals typed as HERC2 rs12913832 G. However, both methods had difficulties in categorizing individuals typed as HERC2 rs12913832 GA because of the large variation in eye colour in HERC2 rs12913832 GA individuals. With the use of

  2. Eye muscle test (image)

    MedlinePlus

    ... the extraocular muscles which results in uncontrolled eye movements. The test involves moving the eyes in six different directions in space to evaluate the proper functioning of the extraocular ...

  3. Eye Drop Tips

    MedlinePlus

    ... Involved News About Us Donate In This Section Eye Drop Tips en Español email Send this article ... the reach of children. Steps For Putting In Eye Drops: Start by tilting your head backward while ...

  4. Diabetic Eye Problems

    MedlinePlus

    ... too high. Over time, this can damage your eyes. The most common problem is diabetic retinopathy. It ... light-sensitive tissue at the back of your eye. You need a healthy retina to see clearly. ...

  5. Eye Injuries (For Parents)

    MedlinePlus

    ... and comfortable as possible until help arrives. continue Chemical Exposure Many chemicals, even those found around the house, can damage an eye. If your child gets a chemical in the eye and you know what it ...

  6. Recommended Sports Eye Protectors

    MedlinePlus

    ... Eye Emergencies How to Jump Start a Car Battery Safely Electronic Screens and Your Eyes Nutrition and ... External Resources The Cost of Vision Problems The Future of Vision Vision Problems in the U.S. Healthy ...

  7. LASIK Eye Surgery

    MedlinePlus

    ... conditions. These conditions include: Autoimmune disorders, such as rheumatoid arthritis Immunodeficiency conditions caused by immunosuppressive medications or HIV Persistent dry eyes Unstable vision due to medications, hormonal changes, pregnancy, breast-feeding or age Several eye conditions, such ...

  8. Diabetes and eye disease

    MedlinePlus

    ... have damage to the blood vessels in your eye, some types of exercise can make the problem worse. Check with your health care provider before starting an exercise program. Other eye problems that can occur in people with diabetes ...

  9. Mountain chickadee (Poecile gambeli)

    USGS Publications Warehouse

    McCallum, D. Archibald; Grundel, Ralph; Dahlsten, Donald L.; Poole, Alan; Gill, Frank

    1999-01-01

    The Mountain Chickadee (Poecile gambeli), a small, cavity-nesting songbird, is one of the most common birds of montane and coniferous forest from southern Arizona and Baja California north to British Columbia and the Yukon territory. This publication describes the life history of the Mountain Chickadee.

  10. Mountain Pine Beetle

    Treesearch

    Gene D. Amman; Mark D. McGregor; Robert E. Jr. Dolph

    1989-01-01

    The mountain pine beetle, Dendroctonus ponderosae Hopkins, is a member of a group of beetles known as bark beetles: Except when adults emerge and attack new trees, the mountain pine beetle completes its life cycle under the bark. The beetle attacks and kills lodgepole, ponderosa, sugar, and western white pines. Outbreaks frequently develop in lodgepole pine stands that...

  11. Infrared Eye: Prototype 2

    DTIC Science & Technology

    2016-06-07

    The Infrared (IR) Eye was developed with support from the National Search and Rescue Secretariat (NSS), in view of improving the efficiency of...airborne search-and rescue operations. The IR Eye concept is based on the human eye and uses simultaneously two fields of view to optimize area coverage and...within the wide field and slaved to the operator’s line of sight by means of an eye -tracking system. The images from both cameras are fused and shown

  12. Rapid alkaline methylene blue supravital staining for assessment of anterior segment infections.

    PubMed

    Kiuchi, Katsuji

    2016-01-01

    To present the Löffler's alkaline methylene blue technique of staining eye discharges in eyes with anterior segment infections. The Löffler's alkaline methylene blue staining method is a simple staining technique that can be used to differentiate bacterial, viral, and fungal infections. It is a cationic dye that stains cells blue because the positively charged dye is attracted to negatively charged particles such as polyphosphates, DNAs, and RNAs. Specimens collected from patients by swabbing are smeared onto microscope slides and the methylene blue solution is dropped on the slide. The slide is covered with a glass cover slip and examined under a microscope. The entire time from the collection to the viewing is about 30 seconds. Histopathological images of the conjunctival epithelial cells and neutrophils in eye discharges were dyed blue and the nuclei were stained more intensely blue. Bacterial infections consisted mainly of neutrophils, and viral infections consisted mainly of lymphocytes. Löffler's alkaline methylene blue staining can be done in about 30 seconds for diagnosis. Even though this is a one color stain, it is possible to infer the cause of the infection by detection of the absence of bacteria and/or fungi in context of the differential distribution of neutrophils and lymphocytes.

  13. Rapid alkaline methylene blue supravital staining for assessment of anterior segment infections

    PubMed Central

    Kiuchi, Katsuji

    2016-01-01

    Purpose To present the Löffler’s alkaline methylene blue technique of staining eye discharges in eyes with anterior segment infections. Method The Löffler’s alkaline methylene blue staining method is a simple staining technique that can be used to differentiate bacterial, viral, and fungal infections. It is a cationic dye that stains cells blue because the positively charged dye is attracted to negatively charged particles such as polyphosphates, DNAs, and RNAs. Specimens collected from patients by swabbing are smeared onto microscope slides and the methylene blue solution is dropped on the slide. The slide is covered with a glass cover slip and examined under a microscope. The entire time from the collection to the viewing is about 30 seconds. Results Histopathological images of the conjunctival epithelial cells and neutrophils in eye discharges were dyed blue and the nuclei were stained more intensely blue. Bacterial infections consisted mainly of neutrophils, and viral infections consisted mainly of lymphocytes. Conclusions Löffler’s alkaline methylene blue staining can be done in about 30 seconds for diagnosis. Even though this is a one color stain, it is possible to infer the cause of the infection by detection of the absence of bacteria and/or fungi in context of the differential distribution of neutrophils and lymphocytes. PMID:27784986

  14. Which lamp will be optimum to eye? Incandescent, fluorescent or LED etc

    PubMed Central

    Chen, Liang; Zhang, Xiao-Wei

    2014-01-01

    Low frequency flicker, high frequency flicker, strong light, strong blue light, infrared, ultraviolet, electromagnetic radiation, ripple flicker and dimming flicker produced by different lamps have negative impact on vision, eyes and health. Negative impact on eyes resulting in myopia or cataract etc: the solution is to remove all the negative factors by applying upright lighting technology and that is optimum to vision, eyes and health. PMID:24634884

  15. Which lamp will be optimum to eye? Incandescent, fluorescent or LED etc.

    PubMed

    Chen, Liang; Zhang, Xiao-Wei

    2014-01-01

    Low frequency flicker, high frequency flicker, strong light, strong blue light, infrared, ultraviolet, electromagnetic radiation, ripple flicker and dimming flicker produced by different lamps have negative impact on vision, eyes and health. Negative impact on eyes resulting in myopia or cataract etc: the solution is to remove all the negative factors by applying upright lighting technology and that is optimum to vision, eyes and health.

  16. Eye drop neurology.

    PubMed

    Bennetto, Luke; Guly, Catherine; Ormerod, Ian; Plant, Gordon T

    2014-06-01

    Eye drops can help to diagnose and prevent complications of neurological disorders. Guttae ophthalmicae (eye drops) are generally safe because the drugs rarely achieve significant systemic concentrations, although there are rare exceptions. This article covers contemporary pharmacological pupil testing; how to dilate a pupil safely; common reasons why pupils do not respond to drops; and corneal lubrication to prevent complications of weak eye closure.

  17. Eye Movements and Learning.

    ERIC Educational Resources Information Center

    Nesbit, Larry L.

    Research on the use of eye movement indices (such as number of fixations, the average fixation duration, and saccadic movements) as a measure of cognitive processing is reviewed in this paper. Information is provided on the physiology of the eye, computer applications to eye movement study, the influence of stimulus materials and intelligence on…

  18. Fish eye optics

    NASA Astrophysics Data System (ADS)

    Hudec, R.; Michalova, S.

    2017-07-01

    We report on small student (high—school) project of the Czech Academy of Sciences dealing with animal (fish) eyes and possible application in science and technology. Albeit most fishes have refractive eyes, the recent discoveries confirm that some fishes have reflective eyes with strange arrangements as well.

  19. Dwarf Eye Disorder

    ERIC Educational Resources Information Center

    Science Teacher, 2005

    2005-01-01

    Johns Hopkins researchers at the Wilmer Eye Institute have discovered what appears to be the first human gene mutation that causes extreme farsightedness. The researchers report that nanophthalmos, Greek for "dwarf eye," is a rare, potentially blinding disorder caused by an alteration in a gene called MFRP that helps control eye growth and…

  20. Dwarf Eye Disorder

    ERIC Educational Resources Information Center

    Science Teacher, 2005

    2005-01-01

    Johns Hopkins researchers at the Wilmer Eye Institute have discovered what appears to be the first human gene mutation that causes extreme farsightedness. The researchers report that nanophthalmos, Greek for "dwarf eye," is a rare, potentially blinding disorder caused by an alteration in a gene called MFRP that helps control eye growth and…

  1. Eye Movements and Learning.

    ERIC Educational Resources Information Center

    Nesbit, Larry L.

    Research on the use of eye movement indices (such as number of fixations, the average fixation duration, and saccadic movements) as a measure of cognitive processing is reviewed in this paper. Information is provided on the physiology of the eye, computer applications to eye movement study, the influence of stimulus materials and intelligence on…

  2. Keratoglobus: An experience at a tertiary eye care center in India

    PubMed Central

    Rathi, Varsha M; Murthy, Somasheila I; Bagga, Bhupesh; Taneja, Mukesh; Chaurasia, Sunita; Sangwan, Virender S

    2015-01-01

    Context: This study was carried out as a part of an internal audit and is the largest series of patients having keratoglobus, published in the literature. Poor visual acuity of the patients indicates the blinding nature of the disease. Aims: We report our experience with patients having keratoglobus at a tertiary eye care center in India. Settings and Design: Retrospective study. Materials and Methods: We analyzed adults and pediatric patients (<16 years) with keratoglobus, seen during 2008–2012. The age, gender, consanguinity, presenting ocular signs, ocular and systemic associations, visual acuity, corneal topography, and surgeries were documented. Results: Forty-eight patients (mean age 22 ± 15 years, 31 males) having keratoglobus were analyzed. 21 patients (42 eyes) were <16 years. Twelve eyes (16 events) had positive history of trauma. The presenting clinical signs were corneal scars/scars of tear repair (15 eyes), hydrops, healed and acute (14 eyes) and corneal or globe rupture (9 eyes). Best-corrected visual acuity was >20/40 in 6/42 (14.3%) pediatric eyes and 15/53 (28.30%) adults. Visual acuity ranging from counting of fingers to no light perception was noted in 20/53 (37.74%) adults and 21/42 (50%) pediatric patients; 13/20 (65%) with blue sclera and 8/22 eyes (36.37%) without blue sclera. Vernal keratoconjunctivitis was present in one pediatric patient. Choroidal osteoma, retinitis pigmentosa, and retinal detachment were present in adults. Surgeries performed were corneal tear repair (5 eyes), tissue adhesive application (2 eyes), descematopexy (4 eyes) and penetrating keratoplasty (PK - 8 eyes: Three had post-PK glaucoma, graft failure-one eye, 4 patients wore scleral lens - prosthetic replacement of the ocular surface ecosystem). Conclusions: About 50% of pediatric eyes (65% having blue sclera) had no functional vision. Trivial trauma was responsible for corneal rupture indicating need for protective glasses. About 50% patients had post-PK glaucoma

  3. Perception via the Deviated Eye in Strabismus

    PubMed Central

    Economides, John R.; Adams, Daniel L.; Horton, Jonathan C.

    2012-01-01

    Misalignment of the eyes can lead to double vision and visual confusion. However, these sensations are rare when strabismus is acquired early in life, because the extra image is suppressed. To explore the mechanism of perceptual suppression in strabismus, the visual fields were mapped binocularly in 14 human subjects with exotropia. Subjects wore red/blue filter glasses to permit dichoptic stimulation while fixating a central target on a tangent screen. A purple stimulus was flashed at a peripheral location; its reported color (“red” or “blue”) revealed which eye’s image was perceived at that locus. The maps showed a vertical border between the center of gaze for each eye, splitting the visual field into two separate regions. In each region, perception was mediated by only one eye, with suppression of the other eye. Unexpectedly, stimuli falling on the fovea of the deviated eye were seen in all subjects. However, they were perceived in a location shifted by the angle of ocular deviation. This plasticity in the coding of visual direction allows accurate localization of objects everywhere in the visual scene, despite the presence of strabismus. PMID:22836262

  4. Effect of Trypan Blue on Descemet Membrane Elasticity.

    PubMed

    John, Thomas; Patel, Alpesh; Vasavada, Abhay; Singh, Man; Nath, Vandana; Cheng, Anny M S; Sheha, Hosam

    2016-11-01

    To evaluate the effect of trypan blue on the elastic property of Descemet membrane (DM) by atomic force microscopy. Human corneas (n = 10) were obtained from the Illinois Eye Bank (Chicago, IL). The DM was isolated and divided into two halves, one half was stained with ophthalmic trypan blue (Vision Blue, 0.06%, DORC International), whereas the unstained other half served as control. The DM samples were then tested using the atomic force microscope. Data were analyzed using the Hertz model for the evaluation of the Young modulus of elasticity. Atomic force microscopy showed higher cantilever deflection on trypan blue-stained DM compared with control, and the difference was statistically significant (P = 0.03). Force-distance curve analysis also revealed a statistically significant increase in the Young modulus of elasticity in the trypan blue-stained samples (10.5 ± 1.4 kPa) compared with the control (5.8 ± 0.8 kPa), (P < 0.0001). Our results suggest that trypan blue may decrease DM elasticity and consequently increase its stiffness. This may influence the graft adherence when used for endothelial keratoplasty.

  5. Learning the Blues. [Lesson Plan].

    ERIC Educational Resources Information Center

    2001

    This lesson introduces students to the "blues," one of the most distinctive and influential elements of African-American musical tradition. With this lesson plan, students can take a virtual field trip to Memphis, Tennessee, one of the prominent centers of blues activities, and explore the history of the blues in the work of W. C. Handy…

  6. Mountaineering fatalities on Denali.

    PubMed

    McIntosh, Scott E; Campbell, Aaron D; Dow, Jennifer; Grissom, Colin K

    2008-01-01

    Mount McKinley, or Denali, is the tallest mountain in North America and attracts over 1,000 climbers annually from around the world. Since Denali is located within a national park, the National Park Service (NPS) manages mountaineering activities and attempts to maintain a balance of an adventurous experience while promoting safety. We retrospectively reviewed the fatalities on Denali from 1903 to 2006 to assist the NPS, medical personnel, and mountaineers improve safety and reduce fatalities on the mountain. Historical records and the NPS climber database were reviewed. Demographics, mechanisms, and circumstances surrounding each fatality were examined. Fatality rates and odds ratios for country of origin were calculated. From 1903 through the end of the 2006 climbing season, 96 individuals died on Denali. The fatality rate is declining and is 3.08/1,000 summit attempts. Of the 96 deaths, 92% were male, 51% occurred on the West Buttress route, and 45% were due to injuries sustained from falls. Sixty-one percent occurred on the descent and the largest number of deaths in 1 year occurred in 1992. Climbers from Asia had the highest odds of dying on the mountain. Fatalities were decreased by 53% after a NPS registration system was established in 1995. Although mountaineering remains a high-risk activity, safety on Denali is improving. Certain groups have a significantly higher chance of dying. Registration systems and screening methods provide ways to target at-risk groups and improve safety on high altitude mountains such as Denali.

  7. Training the Eyes for Competition: Fighting Eyes.

    ERIC Educational Resources Information Center

    Williams, Darrell; Bradford, Vincent

    1989-01-01

    Fencers should be taught to discipline their eyes to focus on the opponent's hand. The rationale for this strategy as well as drills to develop "hand watching" skills are presented in this article. (IAH)

  8. The Blue Emu

    NASA Technical Reports Server (NTRS)

    Descalzi, Doug; Gillett, John; Gordon, Carlton; Keener, ED; Novak, Ken; Puente, Laura

    1993-01-01

    The primary goal in designing the Blue Emu was to provide an airline with a cost efficient and profitable means of transporting passengers between the major cities in Aeroworld. The design attacks the market where a demand for inexpensive transportation exists and for this reason the Blue Emu is an attractive investment for any airline. In order to provide a profitable aircraft, special attention was paid to cost and economics. For example, in manufacturing, simplicity was stressed in structural design to reduce construction time and cost. Aerodynamic design employed a tapered wing which reduced the induced drag coefficient while also reducing the weight of the wing. Even the propulsion system was selected with cost effectiveness in mind, yet also to maintain the marketability of the aircraft. Thus, in every aspect of the design, consideration was given to economics and marketability of the final product.

  9. Thematic Mapper Analysis of Blue Oak (Quercus douglasii) in Central California

    Treesearch

    Paul A. Lefebvre Jr.; Frank W. Davis; Mark Borchert

    1991-01-01

    Digital Thematic Mapper (TM) satellite data from September 1986 and December 1985 were analyzed to determine seasonal reflectance properties of blue oak rangeland in the La Panza mountains of San Luis Obispo County. Linear regression analysis was conducted to examine relationships between TM reflectance and oak canopy cover, basal area, and site topographic variables....

  10. Chick eyes compensate for chromatic simulations of hyperopic and myopic defocus: evidence that the eye uses longitudinal chromatic aberration to guide eye-growth.

    PubMed

    Rucker, Frances J; Wallman, Josh

    2009-07-01

    Longitudinal chromatic aberration (LCA) causes short wavelengths to be focused in front of long wavelengths. This chromatic signal is evidently used to guide ocular accommodation. We asked whether chick eyes exposed to static gratings simulating the chromatic effects of myopic or hyperopic defocus would "compensate" for the simulated defocus. We alternately exposed one eye of each chick to a sine-wave grating (5 or 2 cycle/deg) simulating myopic defocus ("MY defocus": image focused in front of retina; hence, red contrast higher than blue) and the other eye to a grating of the same spatial frequency simulating hyperopic defocus ("HY defocus": blue contrast higher than red). The chicks were placed in a drum with one eye covered with one grating, and then switched to another drum with the other grating with the other eye covered. To minimize the effects of altered eye-growth on image contrast, we studied only the earliest responses: first, we measured changes in choroidal thickness 45 min to 1 h after one 15-min episode in the drum, then we measured glycosaminoglycans (GAG) synthesis in sclera and choroid (by the incorporation of labeled sulfate in tissue culture) after a day of four 30-min episodes in the drum. The eyes compensated in the appropriate directions: The choroids of the eyes exposed to the HY simulation showed significantly more thinning (less thickening) over the course of the experiment than the choroids of the eyes exposed to the MY simulation (all groups mean:-17 microm; 5 c/d groups: -24 microm; paired t-test (one-tailed): p=0.0006). The rate of scleral GAG synthesis in the eye exposed to the HY simulation was significantly greater than in the eye exposed to the MY simulation (HY/MY ratio=1.20; one sample t-test (one-tailed): p=0.015). There was no significant interaction between the sign of the simulated defocus and either the spatial frequency or the presence of a +3 D lens used to compensate for the 33 cm distance of the drum. Although previous

  11. Chick eyes compensate for chromatic simulations of hyperopic and myopic defocus: Evidence that the eye uses longitudinal chromatic aberration to guide eye-growth

    PubMed Central

    Wallman, Josh

    2009-01-01

    Longitudinal chromatic aberration (LCA) causes short wavelengths to be focused in front of long wavelengths. This chromatic signal is evidently used to guide ocular accommodation. We asked whether chick eyes exposed to static gratings simulating the chromatic effects of myopic or hyperopic defocus would “compensate” for the simulated defocus. We alternately exposed one eye of each chick to a sine-wave grating (5 or 2 cycle/deg) simulating myopic defocus (“MY defocus”: image focused in front of retina; hence, red contrast higher than blue) and the other eye to a grating of the same spatial frequency simulating hyperopic defocus (“HY defocus”: blue contrast higher than red). The chicks were placed in a drum with one eye covered, with one grating, and then switched to another drum with the other eye covered, with the other grating. To minimize the effects of altered eye-growth on image contrast, we studied only the earliest responses: first, we measured changes in choroidal thickness 45 min to 1 hour after one 15-min episode in the drum, then we measured glycosaminoglycans (GAG) synthesis in sclera and choroid (by the incorporation of labeled sulfate in tissue culture) after a day of four 30-min episodes in the drum. The eyes compensated in the appropriate directions: The choroids of the eyes exposed to the HY simulation showed significantly more thinning (less thickening) over the course of the experiment than the choroids of the eyes exposed to the MY simulation (all groups mean: −17 μm; 5 c/d groups: −24 μm; paired t-test (one-tailed): p=0.0006). The rate of scleral GAG synthesis in the eye exposed to the HY simulation was significantly greater than in the eye exposed to the MY simulation (HY/MY ratio = 1.20; one sample t-test (one-tailed): p=0.015). There was no significant interaction between the sign of the simulated defocus and either the spatial frequency or the presence of a +3 D lens used to compensate for the 33 cm distance of the drum

  12. Why is the tongue of blue-tongued skinks blue? Reflectance of lingual surface and its consequences for visual perception by conspecifics and predators

    NASA Astrophysics Data System (ADS)

    Abramjan, Andran; Bauerová, Anna; Somerová, Barbora; Frynta, Daniel

    2015-08-01

    Blue-tongued skinks of the genus Tiliqua (Scincidae) are characterized by their large blue melanin-pigmented tongues, often displayed during open-mouth threats, when the animal feels endangered. It is not clear whether this unusual coloration is a direct anti-predation adaptation or it may rather serve intraspecific communication, as ultraviolet-blue color is a frequent visual signal in a number of lizard species. We used spectrophotometry and visual modeling to compare blue tongues of Tiliqua gigas with tongues and skin coloration of other lizard species, and to examine their appearance through the eyes of both the conspecifics and avian predators. Our results show that (1) the tongue coloration is probably not substantially influenced by the amount of melanin in the skin, (2) lingual and oral tissues are UV-reflective in general, with blue colored tongues having chromatic qualities similar to UV-blue skin patches of other lizard species, (3) UV-blue tongues are more conspicuous than pink tongues, especially in the visual model of conspecifics. We hypothesize that blue tongues may possibly serve as a semantic (honest) signal analogous to UV-blue skin patches of other lizard species due to greater UV-bias in the vision of diurnal lizards. Regarding the social behavior and high aggressiveness in Tiliqua and their relatives, such signal might serve, e.g., in intraspecific long-distance communication between conspecifics in order to avoid aggression, and its anti-predation effect may only be a secondary function (exaptation).

  13. Voyager 1 'Blue Movie'

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This is the original Voyager 'Blue Movie' (so named because it was built from Blue filter images). It records the approach of Voyager 1 during a period of over 60 Jupiter days. Notice the difference in speed and direction of the various zones of the atmosphere. The interaction of the atmospheric clouds and storms shows how dynamic the Jovian atmosphere is.

    As Voyager 1 approached Jupiter in 1979, it took images of the planet at regular intervals. This sequence is made from 66 images taken once every Jupiter rotation period (about 10 hours). This time-lapse movie uses images taken every time Jupiter longitude 68W passed under the spacecraft. These images were acquired in the Blue filter from Jan. 6 to Feb. 3 1979. The spacecraft flew from 58 million kilometers to 31 million kilometers from Jupiter during that time.

    This time-lapse movie was produced at JPL by the Image Processing Laboratory in 1979.

  14. Blue metal-poor stars

    NASA Astrophysics Data System (ADS)

    Preston, George W.; Sneden, Christopher

    2004-12-01

    We review the discovery of blue metal-poor (BMP) stars and the resolution of this population into blue stragglers and intermediate-age Main-Sequence stars by use of binary fractions. We show that the specific frequencies of blue stragglers in the halo field and in globular clusters differ by an order of magnitude. We attribute this difference to the different modes of production of these two populations. We report carbon and s-process enrichment among very metal-poor field blue stragglers and discuss how this result can be used to further resolve field blue stragglers into groups formed during RGB and AGB evolution of their erstwhile primary companions.

  15. Space Radar Image of Mammoth Mountain, California

    NASA Image and Video Library

    1999-05-01

    This false-color composite radar image of the Mammoth Mountain area in the Sierra Nevada Mountains, California, was acquired by the Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar aboard the space shuttle Endeavour on its 67th orbit on October 3, 1994. The image is centered at 37.6 degrees north latitude and 119.0 degrees west longitude. The area is about 39 kilometers by 51 kilometers (24 miles by 31 miles). North is toward the bottom, about 45 degrees to the right. In this image, red was created using L-band (horizontally transmitted/vertically received) polarization data; green was created using C-band (horizontally transmitted/vertically received) polarization data; and blue was created using C-band (horizontally transmitted and received) polarization data. Crawley Lake appears dark at the center left of the image, just above or south of Long Valley. The Mammoth Mountain ski area is visible at the top right of the scene. The red areas correspond to forests, the dark blue areas are bare surfaces and the green areas are short vegetation, mainly brush. The purple areas at the higher elevations in the upper part of the scene are discontinuous patches of snow cover from a September 28 storm. New, very thin snow was falling before and during the second space shuttle pass. In parallel with the operational SIR-C data processing, an experimental effort is being conducted to test SAR data processing using the Jet Propulsion Laboratory's massively parallel supercomputing facility, centered around the Cray Research T3D. These experiments will assess the abilities of large supercomputers to produce high throughput Synthetic Aperture Radar processing in preparation for upcoming data-intensive SAR missions. The image released here was produced as part of this experimental effort. http://photojournal.jpl.nasa.gov/catalog/PIA01746

  16. Coronas and iridescence in mountain wave clouds.

    PubMed

    Shaw, Joseph A; Neiman, Paul J

    2003-01-20

    We use Fraunhofer diffraction theory and meterological data to determine the nature of cloud-particle distributions and the mean particle sizes required for interpreting photographs of coronas and iridescence in mountain wave clouds. Traditional descriptions of coronas and iridescence usually explain these optical phenomena as diffraction by droplets of liquid water. Our analysis shows that the photographed displays have mean particle sizes from 7.6 to 24.3 microm, with over half the cases requiring diffraction by small (approximatley 20 microm) quasispherical ice particles rather than liquid water droplets. Previous documentation of coronas produced by ice particles are limited to observations in cirrus clouds that appear to be composed of small ice crystals, whereas our observations suggest that coronas and iridescence quite often can be created by tiny quasispherical ice particles that might be unique to mountain wave clouds. Furthermore, we see that the dominant colors in mountain wave-cloud coronas are red and blue, rather than the traditionally described red and green.

  17. Mountain regions in peril

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    The United Nations has declared 2002 the International Year of Mountains (IYM) to bring attention to a number of threats that affect ecosystems and human populations in mountainous and highland regions around the world.“More than half of humanity—3 billion people—relies on mountains for safe, fresh water, water to grow food, to produce electricity to sustain industries and, most important, water to drink,“ said Jacques Diouf, director-general of the U.N. Food and Agriculture Organization, the primary IYM sponsor. “Yet, mountain glaciers, the source of water for many of the world's river systems and people, are melting at unprecedented rates.”

  18. Low-energy light bulbs, computers, tablets and the blue light hazard

    PubMed Central

    O'Hagan, J B; Khazova, M; Price, L L A

    2016-01-01

    The introduction of low energy lighting and the widespread use of computer and mobile technologies have changed the exposure of human eyes to light. Occasional claims that the light sources with emissions containing blue light may cause eye damage raise concerns in the media. The aim of the study was to determine if it was appropriate to issue advice on the public health concerns. A number of sources were assessed and the exposure conditions were compared with international exposure limits, and the exposure likely to be received from staring at a blue sky. None of the sources assessed approached the exposure limits, even for extended viewing times. PMID:26768920

  19. Low-energy light bulbs, computers, tablets and the blue light hazard.

    PubMed

    O'Hagan, J B; Khazova, M; Price, L L A

    2016-02-01

    The introduction of low energy lighting and the widespread use of computer and mobile technologies have changed the exposure of human eyes to light. Occasional claims that the light sources with emissions containing blue light may cause eye damage raise concerns in the media. The aim of the study was to determine if it was appropriate to issue advice on the public health concerns. A number of sources were assessed and the exposure conditions were compared with international exposure limits, and the exposure likely to be received from staring at a blue sky. None of the sources assessed approached the exposure limits, even for extended viewing times.

  20. Unilateral anterior ischemic optic neuropathy: chromatic pupillometry in affected, fellow non-affected and healthy control eyes.

    PubMed

    Herbst, Kristina; Sander, Birgit; Lund-Andersen, Henrik; Wegener, Marianne; Hannibal, Jens; Milea, Dan

    2013-01-01

    The intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, which is sensitive to blue light. Previous chromatic pupillometry studies have shown that the post-illumination response is considered an indicator of the melanopsin activation. The aim of this study was to investigate the ipRGC mediated pupil response in patients with a unilateral non-arteritic anterior ischemic optic neuropathy (NAION). Consensual pupil responses during and after exposure to continuous 20 s blue (470 nm) or red (660 nm) light of high intensity (300 cd/m(2)) were recorded in each eye for 10 patients. Comparisons were performed both intra-individually (affected versus non-affected eyes) and inter-individually (compared with healthy controls). The pupil response was calculated both during the illumination and during the post-illumination phase. The pupil responses to blue and red colors were significantly reduced in the NAION-affected eyes, compared with the fellow non-affected eyes. When comparing the affected eyes with the healthy control eyes, the post-illumination responses were not significantly different. In addition, the post-illumination pupil responses after blue light exposure were increased in the fellow non-affected patients' eyes, compared with the healthy controls. However, significance was only reached for the late post-illumination response. In conclusion, chromatic pupillometry disclosed reduced post-illumination pupil responses in the NAION-affected eyes, compared with the non-affected fellow eyes, suggesting dysfunction of the ipRGCs. Compared with the responses of the healthy controls, the blue light post-illumination pupil responses were similar in the affected eyes and increased in the fellow non-affected eyes. This suggests a possible adaptive phenomenon, involving the ipRGCs of both eyes after unilateral NAION.

  1. Organic contaminants in mountains.

    PubMed

    Daly, Gillian L; Wania, Frank

    2005-01-15

    The study of organic contaminants at high altitudes is motivated by the potential risk that they pose to humans living in, or depending on resources derived from, mountains and to terrestrial and aquatic ecosystems in alpine areas. Mountains are also ideal settings to study contaminant transport and behavior along gradients of climate and surface cover. Information on organic contaminants in mountains is compiled from the literature and synthesized, with a focus on atmospheric transport and deposition, contaminant dynamics in alpine lakes and aquatic organisms, and concentration differences with altitude. Diurnal mountain winds, in connection with enhanced deposition at higher elevations caused by low temperatures and high precipitation rates, conspire to make mid-latitude mountains become convergence zones for selected persistent organic chemicals. In particular, the more volatile constituents of contaminant mixtures seem to become enriched, relative to the less volatile constituents at higher altitudes. For selected contaminants, concentration inversions (i.e., concentrations that increase with elevation) have been observed. A notable difference between cold trapping in high latitudes and high altitudes is the likely importance of precipitation. High rates of snow deposition in mid- and high-latitude mountains may lead to a large contaminant release during snowmelt. Regions above the tree line often have little capacity to retain the released contaminants, suggesting the potential for a highly dynamic contaminant fate situation during the snow-free season with significant revolatilization and runoff. The chemical and environmental factors that control the orographic cold trapping of organic contaminants should be examined further by measuring and comparatively interpreting concentration gradients along several mountain slopes with widely different characteristics. Future efforts should further focus on the bioaccumulation and potential effects of contaminants in

  2. Mountain Rivers Revisited

    NASA Astrophysics Data System (ADS)

    Schultz, Colin

    2011-12-01

    Published in 2000, the original Mountain Rivers was written to provide a concise summary of the scientific understanding of the distinct subset of rivers that gave the book its name. Spurred by developments in the field in the past decade, the book's author, Ellen Wohl, produced Mountain Rivers Revisited, an updated edition aimed at graduate students and professional researchers. In this interview, Eos talks to Wohl about steep channels, climate change, and opportunities for future research.

  3. YUCCA MOUNTAIN SITE DESCRIPTION

    SciTech Connect

    A.M. Simmons

    2004-04-16

    The ''Yucca Mountain Site Description'' summarizes, in a single document, the current state of knowledge and understanding of the natural system at Yucca Mountain. It describes the geology; geochemistry; past, present, and projected future climate; regional hydrologic system; and flow and transport within the unsaturated and saturated zones at the site. In addition, it discusses factors affecting radionuclide transport, the effect of thermal loading on the natural system, and tectonic hazards. The ''Yucca Mountain Site Description'' is broad in nature. It summarizes investigations carried out as part of the Yucca Mountain Project since 1988, but it also includes work done at the site in earlier years, as well as studies performed by others. The document has been prepared under the Office of Civilian Radioactive Waste Management quality assurance program for the Yucca Mountain Project. Yucca Mountain is located in Nye County in southern Nevada. The site lies in the north-central part of the Basin and Range physiographic province, within the northernmost subprovince commonly referred to as the Great Basin. The basin and range physiography reflects the extensional tectonic regime that has affected the region during the middle and late Cenozoic Era. Yucca Mountain was initially selected for characterization, in part, because of its thick unsaturated zone, its arid to semiarid climate, and the existence of a rock type that would support excavation of stable openings. In 1987, the United States Congress directed that Yucca Mountain be the only site characterized to evaluate its suitability for development of a geologic repository for high-level radioactive waste and spent nuclear fuel.

  4. "Brilliant Blue G" and "Membrane Blue Dual" assisted vitrectomy for macular hole.

    PubMed

    Kovacević, Damir; Mance, Tea Caljkusić; Markusić, Vedran

    2011-09-01

    The aim of this study is to evaluate vital dyes "Brilliant Blue G" (BBG) and "Membrane Blue Dual" (MBD) for intraoperative staining of the inner limiting membrane (ILM) during vitrectomy for macular hole (MH). Retrospective, comparative case series on 18 eyes with macular holes who underwent "23 and 25 gauge" pars plana vitrectomy. Main outcome measurements were staining intensity and characteristics, visual acuity, visual field, OCT measurements and complications over a period of 6 months. With the help of BBG and MBD successfully was removed complete ILM in 14 eyes. Postoperative visual acuity was improved in 12 patients, unchanged in 2 patients and worse in 4 patients. Central retinal thickness showed significant postoperative reduction with closure of macular hole. OCT values range were from -10 to -250 microm. No visual field defects and no adverse effects were found. BBG and MBD successfully identificate internal limiting membrane during vitrectomy for MH. Good anatomical and functional results are achieved with the use of both vital dyes.

  5. The Convergent Evolution of Blue Iris Pigmentation in Primates Took Distinct Molecular Paths

    PubMed Central

    Meyer, Wynn K; Zhang, Sidi; Hayakawa, Sachiko; Imai, Hiroo; Przeworski, Molly

    2013-01-01

    How many distinct molecular paths lead to the same phenotype? One approach to this question has been to examine the genetic basis of convergent traits, which likely evolved repeatedly under a shared selective pressure. We investigated the convergent phenotype of blue iris pigmentation, which has arisen independently in four primate lineages: humans, blue-eyed black lemurs, Japanese macaques, and spider monkeys. Characterizing the phenotype across these species, we found that the variation within the blue-eyed subsets of each species occupies strongly overlapping regions of CIE L*a*b* color space. Yet whereas Japanese macaques and humans display continuous variation, the phenotypes of blue-eyed black lemurs and their sister species (whose irises are brown) occupy more clustered subspaces. Variation in an enhancer of OCA2 is primarily responsible for the phenotypic difference between humans with blue and brown irises. In the orthologous region, we found no variant that distinguishes the two lemur species or associates with quantitative phenotypic variation in Japanese macaques. Given the high similarity between the blue iris phenotypes in these species and that in humans, this finding implies that evolution has used different molecular paths to reach the same end. Am J Phys Anthropol 151:398–407, 2013.© 2013 Wiley Periodicals, Inc. PMID:23640739

  6. The convergent evolution of blue iris pigmentation in primates took distinct molecular paths.

    PubMed

    Meyer, Wynn K; Zhang, Sidi; Hayakawa, Sachiko; Imai, Hiroo; Przeworski, Molly

    2013-07-01

    How many distinct molecular paths lead to the same phenotype? One approach to this question has been to examine the genetic basis of convergent traits, which likely evolved repeatedly under a shared selective pressure. We investigated the convergent phenotype of blue iris pigmentation, which has arisen independently in four primate lineages: humans, blue-eyed black lemurs, Japanese macaques, and spider monkeys. Characterizing the phenotype across these species, we found that the variation within the blue-eyed subsets of each species occupies strongly overlapping regions of CIE L*a*b* color space. Yet whereas Japanese macaques and humans display continuous variation, the phenotypes of blue-eyed black lemurs and their sister species (whose irises are brown) occupy more clustered subspaces. Variation in an enhancer of OCA2 is primarily responsible for the phenotypic difference between humans with blue and brown irises. In the orthologous region, we found no variant that distinguishes the two lemur species or associates with quantitative phenotypic variation in Japanese macaques. Given the high similarity between the blue iris phenotypes in these species and that in humans, this finding implies that evolution has used different molecular paths to reach the same end. Copyright © 2013 Wiley Periodicals, Inc.

  7. Mars Through Infrared Eyes of Spirit

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This image shows the martian terrain through the eyes of the Mars Exploration Rover Spirit's mini-thermal emission spectrometer, an instrument that detects the infrared light, or heat, emitted by objects. The different colored circles show a spectrum of soil and rock temperatures, with red representing warmer regions and blue, cooler. A warm and dusty depression similar to the one dubbed Sleepy Hollow stands out to the upper right. Scientists and engineers will use this data to pinpoint features of interest, and to plot a safe course for the rover free of loose dust. The mini-thermal emission spectrometer data are superimposed on an image taken by the rover's panoramic camera.

  8. Mars Through Infrared Eyes of Spirit-2

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This image shows the martian terrain through the eyes of the Mars Exploration Rover Spirit's mini-thermal emission spectrometer, an instrument that detects the infrared light, or heat, emitted by objects. The different colored circles show a spectrum of soil and rock temperatures, with red representing warmer regions and blue, cooler. Clusters of cool rocks can be seen to the left and center. Scientists and engineers will use this data to pinpoint features of interest, and to plot a safe course for the rover free of loose dust. The mini-thermal emission spectrometer data are superimposed on an image taken by the rover's panoramic camera.

  9. Mars Through Infrared Eyes of Spirit

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This image shows the martian terrain through the eyes of the Mars Exploration Rover Spirit's mini-thermal emission spectrometer, an instrument that detects the infrared light, or heat, emitted by objects. The different colored circles show a spectrum of soil and rock temperatures, with red representing warmer regions and blue, cooler. A warm and dusty depression similar to the one dubbed Sleepy Hollow stands out to the upper right. Scientists and engineers will use this data to pinpoint features of interest, and to plot a safe course for the rover free of loose dust. The mini-thermal emission spectrometer data are superimposed on an image taken by the rover's panoramic camera.

  10. Mars Through Infrared Eyes of Spirit-2

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This image shows the martian terrain through the eyes of the Mars Exploration Rover Spirit's mini-thermal emission spectrometer, an instrument that detects the infrared light, or heat, emitted by objects. The different colored circles show a spectrum of soil and rock temperatures, with red representing warmer regions and blue, cooler. Clusters of cool rocks can be seen to the left and center. Scientists and engineers will use this data to pinpoint features of interest, and to plot a safe course for the rover free of loose dust. The mini-thermal emission spectrometer data are superimposed on an image taken by the rover's panoramic camera.

  11. Yucca Mountain nuclear waste repository prompts heated congressional hearing

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-11-01

    Although the final report of the Blue Ribbon Commission on America's Nuclear Future is not expected until January 2012, the tentative conclusions of the commission's draft report were dissected during a recent joint hearing by two subcommittees of the House of Representatives' Committee on Science, Space, and Technology. Among the more heated issues debated at the hearing was the fate of the stalled Yucca Mountain nuclear waste repository in Nevada. The Blue Ribbon Commission's (BRC) draft report includes recommendations for managing nuclear waste and for developing one or more permanent deep geological repositories and interim storage facilities, but the report does not address the future of Yucca Mountain. The BRC charter indicates that the commission is to "conduct a comprehensive review of policies for managing the back end of the nuclear fuel cycle." However, the draft report states that the commission was not asked to consider, and therefore did not address, several key issues. "We have not rendered an opinion on the suitability of the Yucca Mountain site or on the request to withdraw the license application for Yucca Mountain," the draft report states.

  12. Near-infrared spectral mapping of Titan's mountains and channels

    USGS Publications Warehouse

    Barnes, J.W.; Radebaugh, J.; Brown, R.H.; Wall, S.; Soderblom, L.; Lunine, J.; Burr, D.; Sotin, Christophe; Le, Mouelic S.; Rodriguez, S.; Buratti, B.J.; Clark, R.; Baines, K.H.; Jaumann, R.; Nicholson, P.D.; Kirk, R.L.; Lopes, R.; Lorenz, R.D.; Mitchell, Ken; Wood, C.A.

    2007-01-01

    We investigate the spectral reflectance properties of channels and mountain ranges on Titan using data from Cassini's Visual and Infrared Mapping Spectrometer (VIMS) obtained during the T9 encounter (26 December 2005). We identify the location of channels and mountains using synthetic aperture radar maps obtained from Cassini's RADAR instrument during the T13 (30 April 2006) flyby. Channels are evident even in VIMS imaging with spatial resolution coarser than the channel size. The channels share spectral characteristics with Titan's dark blue terrain (e.g., the Huygens landing site) that is consistent with an enhancement in water ice content relative to the rest of Titan. We use this fact to measure widths of ???1 km for the largest channels. Comparison of the data sets shows that in our study area within the equatorial bright spectral unit east of Xanadu, mountains are darker and bluer than surrounding smooth terrain. These results are consistent with the equatorial bright terrain possessing a veneer of material that is thinner in the regions where there are mountains and streambeds that have likely undergone more recent and extensive erosion. We suggest a model for the geographic relationship of the dark blue, dark brown, and equatorial bright spectral units based on our findings. Copyright 2007 by the American Geophysical Union.

  13. Role of the iridescent eye in stickleback female mate choice.

    PubMed

    Flamarique, Iñigo Novales; Bergstrom, Carolyn; Cheng, Christiana L; Reimchen, Thomas E

    2013-08-01

    Many vertebrates exhibit prominent body colours that are used in courtship and territorial communication. Some fishes also have an eye whose iris becomes iridescent during the mating season, as in the threespine stickleback. Behavioural studies in this species have focused on the redness of the throat/jaw as the primary determinant of female mate choice. Unlike the iridescent eye, however, the red throat/jaw is not present in all stickleback populations, suggesting that the colour of the eye may be equally important for female mate choice. Here, we used data on photoreceptors and environmental light to assess body conspicuousness and the colour contrast of courtship signals for stickleback populations living in a range of waters, from clear (mesotrophic) to red light shifted (dystrophic). This analysis indicated that the redness of the throat/jaw is expressed to enhance the contrast of the eye. To test the importance of eye colour as a courtship signal, we carried out mate choice experiments in which females were presented with identical videos of a courting male but for the colour of the eye and/or the throat/jaw. Females did not choose based on differences in throat/jaw redness between videos, but preferred males with the highest contrast between the eye and the throat/jaw. This result points to the blue iridescent eye as a primary courtship signal in stickleback female mate choice.

  14. European eye bank association.

    PubMed

    Jones, Gary L A; Ponzin, Diego; Pels, Elisabeth; Maas, Hanneke; Tullo, Andrew B; Claerhout, Ilse

    2009-01-01

    The European Eye Bank Association (EEBA) is a technical-scientific organization for eye banks. Founded in 1989 with the simple objective of sharing information on eye banking, the Association is today the leading pan-national association in Europe dedicated to the advancement of eye banking and an authoritative reference point for eye banks which work according to quality standards. The Association establishes and maintains an agreed set of medical and technical standards, promotes the collection of data on eye bank activities and processes, provides opportunities for the discussion of all aspects of eye banking practice, including eye donor selection and procurement, relevant research and development, education and training in eye banking, and maintains linkage with national and international corneal transplant communities and relevant bodies. The recent introduction of a more structured and focused committee, a permanent secretariat, the development of a website has enabled the Association to establish closer links and collaborative activities with key regulatory bodies and to provide a more constant exchange of clinical, scientific and technical ideas and best practice with fellow professionals by means of its annual meetings, the EEBA directory and website, and a regular newsletter. The EEBA is a scientific organization committed to defining minimum standards and to encouraging eye banks to maintain the highest possible standards for quality and safety. Through its annual meetings, and the collection and exchange of detailed information from member eye banks, the Association can rightly claim to speak with a confident and representative voice on eye banking in Europe. Copyright 2009 S. Karger AG, Basel.

  15. Further development of forensic eye color predictive tests.

    PubMed

    Ruiz, Y; Phillips, C; Gomez-Tato, A; Alvarez-Dios, J; Casares de Cal, M; Cruz, R; Maroñas, O; Söchtig, J; Fondevila, M; Rodriguez-Cid, M J; Carracedo, A; Lareu, M V

    2013-01-01

    In forensic analysis predictive tests for external visible characteristics (or EVCs), including inference of iris color, represent a potentially useful tool to guide criminal investigations. Two recent studies, both focused on forensic testing, have analyzed single nucleotide polymorphism (SNP) genotypes underlying common eye color variation (Mengel-From et al., Forensic Sci. Int. Genet. 4:323 and Walsh et al., Forensic Sci. Int. Genet. 5:170). Each study arrived at different recommendations for eye color predictive tests aiming to type the most closely associated SNPs, although both confirmed rs12913832 in HERC2 as the key predictor, widely recognized as the most strongly associated marker with blue and brown iris colors. Differences between these two studies in identification of other eye color predictors may partly arise from varying approaches to assigning phenotypes, notably those not unequivocally blue or dark brown and therefore occupying an intermediate iris color continuum. We have developed two single base extension assays typing 37 SNPs in pigmentation-associated genes to study SNP-genotype based prediction of eye, skin, and hair color variation. These assays were used to test the performance of different sets of eye color predictors in 416 subjects from six populations of north and south Europe. The presence of a complex and continuous range of intermediate phenotypes distinct from blue and brown eye colors was confirmed by establishing eye color populations compared to genetic clusters defined using Structure software. Our study explored the effect of an expanded SNP combination beyond six markers has on the ability to predict eye color in a forensic test without extending the SNP assay excessively - thus maintaining a balance between the test's predictive value and an ability to reliably type challenging DNA with a multiplex of manageable size. Our evaluation used AUC analysis (area under the receiver operating characteristic curves) and na

  16. Ocular Emergencies: Red Eye.

    PubMed

    Tarff, Andreina; Behrens, Ashley

    2017-05-01

    "Red eye" is used as a general term to describe irritated or bloodshot eyes. It is a recognizable sign of an acute/chronic, localized/systemic underlying inflammatory condition. Conjunctival injection is most commonly caused by dryness, allergy, visual fatigue, contact lens overwear, and local infections. In some instances, red eye can represent a true ocular emergency that should be treated by an ophthalmologist. A comprehensive assessment of red eye conditions is required to preserve the patients visual function. Severe ocular pain, significant photophobia, decreased vision, and history of ocular trauma are warning signs demanding immediate ophthalmological consultation. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. A deep water turbidity origin for the Altuda Formation (Capitanian, Permian), Northwest Glass Mountains, Texas

    USGS Publications Warehouse

    Haneef, Mohammad; Rohr, D.M.; Wardlaw, B.R.

    2000-01-01

    The Altuda Formation (Capitanian) in the northwestern Glass Mountains is comprised of thin, even bedded limestones, dolostones, mixed clastic-carbonates, and silt/sandstones interbedded with basin-ward dipping wedge-shaped clinoforms of the Captian Limestone. The formation is characterized by graded bedding, planar laminations, flame structures, contorted/convolute bedding, horizontal branching burrows, and shelf-derived normal marine fauna. A detailed study of the Altuda Formation north of Old Blue Mountain, Glass Mountains, reveals that the formation in this area was deposited by turbidity currents in slope to basinal settings.

  18. The Blue Marble

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This spectacular Moderate Resolution Imaging Spectroradiometer (MODIS) 'blue marble' image is based on the most detailed collection of true-color imagery of the entire Earth to date. Using a collection of satellite-based observations, scientists and visualizers stitched together months of observations of the land surface, oceans, sea ice, and clouds into a seamless, true-color mosaic of every square kilometer (.386 square mile) of our planet. Most of the information contained in this image came from MODIS, illustrating MODIS' outstanding capacity to act as an integrated tool for observing a variety of terrestrial, oceanic, and atmospheric features of the Earth. The land and coastal ocean portions of this image is based on surface observations collected from June through September 2001 and combined, or composited, every eight days to compensate for clouds that might block the satellite's view on any single day. Global ocean color (or chlorophyll) data was used to simulate the ocean surface. MODIS doesn't measure 3-D features of the Earth, so the surface observations were draped over topographic data provided by the U.S. Geological Survey EROS Data Center. MODIS observations of polar sea ice were combined with observations of Antarctica made by the National Oceanic and Atmospheric Administration's AVHRR sensor-the Advanced Very High Resolution Radiometer. The cloud image is a composite of two days of MODIS imagery collected in visible light wavelengths and a third day of thermal infra-red imagery over the poles. A large collection of imagery based on the blue marble in a variety of sizes and formats, including animations and the full (1 km) resolution imagery, is available at the Blue Marble page. Image by Reto Stockli, Render by Robert Simmon. Based on data from the MODIS Science Team

  19. The Blue Marble

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This spectacular Moderate Resolution Imaging Spectroradiometer (MODIS) 'blue marble' image is based on the most detailed collection of true-color imagery of the entire Earth to date. Using a collection of satellite-based observations, scientists and visualizers stitched together months of observations of the land surface, oceans, sea ice, and clouds into a seamless, true-color mosaic of every square kilometer (.386 square mile) of our planet. Most of the information contained in this image came from MODIS, illustrating MODIS' outstanding capacity to act as an integrated tool for observing a variety of terrestrial, oceanic, and atmospheric features of the Earth. The land and coastal ocean portions of this image is based on surface observations collected from June through September 2001 and combined, or composited, every eight days to compensate for clouds that might block the satellite's view on any single day. Global ocean color (or chlorophyll) data was used to simulate the ocean surface. MODIS doesn't measure 3-D features of the Earth, so the surface observations were draped over topographic data provided by the U.S. Geological Survey EROS Data Center. MODIS observations of polar sea ice were combined with observations of Antarctica made by the National Oceanic and Atmospheric Administration's AVHRR sensor-the Advanced Very High Resolution Radiometer. The cloud image is a composite of two days of MODIS imagery collected in visible light wavelengths and a third day of thermal infra-red imagery over the poles. A large collection of imagery based on the blue marble in a variety of sizes and formats, including animations and the full (1 km) resolution imagery, is available at the Blue Marble page. Image by Reto Stockli, Render by Robert Simmon. Based on data from the MODIS Science Team

  20. Influence of elevation and forest type on community assemblage and species distribution of shrews in the central and southern Appalachian mountains

    Treesearch

    W. Mark Ford; Timothy S. McCay; Michael A. Menzel; W. David Webster; Cathryn H. Greenberg; John F. Pagels; Joseph F. Merritt; Joseph F. Merritt

    2005-01-01

    We analyzed shrew community data from 398,832 pitfall trapnights at 303 sites across the upper Piedmont, Blue Ridge, northern Ridge and Valley, southern Ridge and Valley, Cumberland Plateau and Allegheny Mountains and Plateau sections of the central and southern Appalachian Mountains from Alabama to Pennsylvania. The objectives of our research were to describe regional...

  1. Influence of elevation and forest type on community assemblage and species distribution of shrews in the central and southern Appalachian mountains

    Treesearch

    W. Mark Ford; Timothy S. McCay; Michael A. Menzel; W. David Webster; Cathryn H. Greenberg; John F. Pagels; Joseph F. Merritt

    2005-01-01

    We analyzed shrew community data from 398,832 pitfall trapnights at 303 sites across the upper Piedmont, Blue ridge, northern Ridge and Valley, southern Ride and Valley, Cumberland Plateau and Allegheny Mountains and Plateau sections of the central and southern Appalachian Mountains from Alabama to Pennsylvania. The objectives of our research were to describe regional...

  2. Influence of elevation and forest type on community assemblage and species distribution of shrews in the central and southern Appalachian Mountains

    Treesearch

    W. Mark Ford; Timothy S. McCay; Michael A. Menzel; W. David Webster; Cathryn H. Greenberg; John F. Pagels; Joseph F. Merritt

    2006-01-01

    We analyzed shrew community data from 398,832 pitfall trapnights at 303 sites across the upper Piedmont, Blue Ridge, northern Ridge and Valley, southern Ridge and Valley, Cumberland Plateau and Allegheny Mountains and Plateau sections of the central and southern Appalachian Mountains from Alabama to Pennsylvania. The objectives of our research were to describe regional...

  3. The Spanish Blue Division

    DTIC Science & Technology

    2005-03-18

    the German North Army Group. WORD COUNT=5933 20 ENDNOTES 1 Torres, Francisco. La Divisi6n Azul50 AFos Despu6s. Madrid: Editorial Fuerza Nueva , 1991,31...osDespu6s. Madrid: Editorial Fuerza Nueva , 1991,47. ’ Kleinfield, Gerald R. and Tambs, Lewis A. La Divisi6n espatjola de Hitler. Madrid: Editorial San Martin...1983, 25. ’ Torres, Francisco. La Divisi6n Azu150AiosDespu6s. Madrid: Editorial Fuerza Nueva , 1991,53 6 The Division was popularly known as the Blue

  4. Blue upconversion thulium laser

    NASA Astrophysics Data System (ADS)

    Nguyen, Dinh C.; Faulkner, George E.; Weber, Michael E.; Dulick, Michael

    1990-04-01

    We report a blue emission upconversion solid-state laser based on Tm3+:YLF. Under double resonance excitation at 780.8 nm (near-ir) and 648.8 nm (red), the Tm3+ ion is sequentially excited from the 3H6 ground state to the 1D2 excited state through the 3H4 intermediate level. The laser output at 450 and 453 nm corresponds to the 1D2 -> 3F4 transitions of Tm3+ ions in YLF.

  5. How bees distinguish patterns by green and blue modulation

    PubMed Central

    Horridge, Adrian

    2015-01-01

    In the 1920s, Mathilde Hertz found that trained bees discriminated between shapes or patterns of similar size by something related to total length of contrasting contours. This input is now interpreted as modulation in green and blue receptor channels as flying bees scan in the horizontal plane. Modulation is defined as total contrast irrespective of sign multiplied by length of edge displaying that contrast, projected to vertical, therefore, combining structure and contrast in a single input. Contrast is outside the eye; modulation is a phasic response in receptor pathways inside. In recent experiments, bees trained to distinguish color detected, located, and measured three independent inputs and the angles between them. They are the tonic response of the blue receptor pathway and modulation of small-field green or (less preferred) blue receptor pathways. Green and blue channels interacted intimately at a peripheral level. This study explores in more detail how various patterns are discriminated by these cues. The direction of contrast at a boundary was not detected. Instead, bees located and measured total modulation generated by horizontal scanning of contrasts, irrespective of pattern. They also located the positions of isolated vertical edges relative to other landmarks and distinguished the angular widths between vertical edges by green or blue modulation alone. The preferred inputs were the strongest green modulation signal and angular width between outside edges, irrespective of color. In the absence of green modulation, the remaining cue was a measure and location of blue modulation at edges. In the presence of green modulation, blue modulation was inhibited. Black/white patterns were distinguished by the same inputs in blue and green receptor channels. Left–right polarity and mirror images could be discriminated by retinotopic green modulation alone. Colors in areas bounded by strong green contrast were distinguished as more or less blue than the

  6. How bees distinguish patterns by green and blue modulation.

    PubMed

    Horridge, Adrian

    2015-01-01

    In the 1920s, Mathilde Hertz found that trained bees discriminated between shapes or patterns of similar size by something related to total length of contrasting contours. This input is now interpreted as modulation in green and blue receptor channels as flying bees scan in the horizontal plane. Modulation is defined as total contrast irrespective of sign multiplied by length of edge displaying that contrast, projected to vertical, therefore, combining structure and contrast in a single input. Contrast is outside the eye; modulation is a phasic response in receptor pathways inside. In recent experiments, bees trained to distinguish color detected, located, and measured three independent inputs and the angles between them. They are the tonic response of the blue receptor pathway and modulation of small-field green or (less preferred) blue receptor pathways. Green and blue channels interacted intimately at a peripheral level. This study explores in more detail how various patterns are discriminated by these cues. The direction of contrast at a boundary was not detected. Instead, bees located and measured total modulation generated by horizontal scanning of contrasts, irrespective of pattern. They also located the positions of isolated vertical edges relative to other landmarks and distinguished the angular widths between vertical edges by green or blue modulation alone. The preferred inputs were the strongest green modulation signal and angular width between outside edges, irrespective of color. In the absence of green modulation, the remaining cue was a measure and location of blue modulation at edges. In the presence of green modulation, blue modulation was inhibited. Black/white patterns were distinguished by the same inputs in blue and green receptor channels. Left-right polarity and mirror images could be discriminated by retinotopic green modulation alone. Colors in areas bounded by strong green contrast were distinguished as more or less blue than the

  7. Statistical eye model for normal eyes.

    PubMed

    Rozema, Jos J; Atchison, David A; Tassignon, Marie-José

    2011-06-23

    To create a binocular statistical eye model based on previously measured ocular biometric data. Thirty-nine parameters were determined for a group of 127 healthy subjects (37 male, 90 female; 96.8% Caucasian) with an average age of 39.9 ± 12.2 years and spherical equivalent refraction of -0.98 ± 1.77 D. These parameters described the biometry of both eyes and the subjects' age. Missing parameters were complemented by data from a previously published study. After confirmation of the Gaussian shape of their distributions, these parameters were used to calculate their mean and covariance matrices. These matrices were then used to calculate a multivariate Gaussian distribution. From this, an amount of random biometric data could be generated, which were then randomly selected to create a realistic population of random eyes. All parameters had Gaussian distributions, with the exception of the parameters that describe total refraction (i.e., three parameters per eye). After these non-Gaussian parameters were omitted from the model, the generated data were found to be statistically indistinguishable from the original data for the remaining 33 parameters (TOST [two one-sided t tests]; P < 0.01). Parameters derived from the generated data were also significantly indistinguishable from those calculated with the original data (P > 0.05). The only exception to this was the lens refractive index, for which the generated data had a significantly larger SD. A statistical eye model can describe the biometric variations found in a population and is a useful addition to the classic eye models.

  8. Blue ocean leadership.

    PubMed

    Kim, W Chan; Mauborgne, Renée

    2014-05-01

    Ten years ago, two INSEAD professors broke ground by introducing "blue ocean strategy," a new model for discovering uncontested markets that are ripe for growth. In this article, they apply their concepts and tools to what is perhaps the greatest challenge of leadership: closing the gulf between the potential and the realized talent and energy of employees. Research indicates that this gulf is vast: According to Gallup, 70% of workers are disengaged from their jobs. If companies could find a way to convert them into engaged employees, the results could be transformative. The trouble is, managers lack a clear understanding of what changes they could make to bring out the best in everyone. Here, Kim and Mauborgne offer a solution to that problem: a systematic approach to uncovering, at each level of the organization, which leadership acts and activities will inspire employees to give their all, and a process for getting managers throughout the company to start doing them. Blue ocean leadership works because the managers' "customers"-that is, the people managers oversee and report to-are involved in identifying what's effective and what isn't. Moreover, the approach doesn't require leaders to alter who they are, just to undertake a different set of tasks. And that kind of change is much easier to implement and track than changes to values and mind-sets.

  9. Automatic Detection of Blue-White Veil and Related Structures in Dermoscopy Images

    PubMed Central

    Celebi, M. Emre; Iyatomi, Hitoshi; Stoecker, William V.; Moss, Randy H.; Rabinovitz, Harold S.; Argenziano, Giuseppe; Soyer, H. Peter

    2011-01-01

    Dermoscopy is a non-invasive skin imaging technique, which permits visualization of features of pigmented melanocytic neoplasms that are not discernable by examination with the naked eye. One of the most important features for the diagnosis of melanoma in dermoscopy images is the blue-white veil (irregular, structureless areas of confluent blue pigmentation with an overlying white “ground-glass” film). In this article, we present a machine learning approach to the detection of blue-white veil and related structures in dermoscopy images. The method involves contextual pixel classification using a decision tree classifier. The percentage of blue-white areas detected in a lesion combined with a simple shape descriptor yielded a sensitivity of 69.35% and a specificity of 89.97% on a set of 545 dermoscopy images. The sensitivity rises to 78.20% for detection of blue veil in those cases where it is a primary feature for melanoma recognition. PMID:18804955

  10. New NASA Infrared Image of Irma Shows an Angry Eye

    NASA Image and Video Library

    2017-09-05

    Hurricane Irma is the strongest hurricane ever recorded outside the Caribbean Sea and Gulf of Mexico. These two images from the Atmospheric Infrared Sounder (AIRS) instrument aboard NASA's Aqua satellite show what Hurricane Irma looked like when Aqua passed overhead just before 1 p.m. local time (10 a.m. PDT) on Sept. 5, 2017. Forecasts at the National Hurricane Center have Irma passing near the major islands to its west before turning northward near Florida this weekend. The first image (top) is an infrared snapshot from AIRS (see Figure 1 for larger image). In orange and red areas, the ocean surface shines through, while blue and purple areas represent cold, high clouds that obscure what lies below. Typical of well-developed hurricanes, Irma is nearly circular with a well-defined eye at its center. The eye is about 25 miles (40 kilometers) in diameter. Careful scrutiny shows a red pixel in the center of the eye, which means that AIRS achieved a bulls-eye with one of its "looks" and was able to see to the ocean between the dense clouds in the eye wall. The second image (bottom) shows the view through AIRS' microwave-colored "lenses" (see Figure 2 for larger image). Here the ocean surface looks yellow, while green represents various degrees of cloudiness. Blue shows areas where it is raining heavily. The eye is not apparent in this image because the "pixel size" of the microwave sounder, about 30 miles (50 kilometers), is larger than the eye and therefore cannot "thread the needle." The infrared sounder, on the other hand, has a pixel size of only 10 miles (16.5 kilometers) and can distinguish the small eye. https://photojournal.jpl.nasa.gov/catalog/PIA21941

  11. Eye proprioception may provide real time eye position information.

    PubMed

    Wang, Jing; Pan, Yujun

    2013-03-01

    Because of the frequency of eye movements, online knowledge of eye position is crucial for the accurate spatial perception and behavioral navigation. Both the internal monitoring signal (corollary discharge) of eye movements and the eye proprioception signal are thought to contribute to the localization of the eye position in the orbit. However, the functional role of these two eye position signals in spatial cognition has been disputed for more than a century. The predominant view proposes that the online analysis of eye position is exclusively provided by the corollary discharge signal, while the eye proprioception signal only plays a role in the long-term calibration of the oculomotor system. However, increasing evidence from recent behavioral and physiological studies suggests that the eye proprioception signal may play a role in the online monitoring of eye position. The purpose of this review is to discuss the feasibility and possible function of the eye proprioceptive signal for online monitoring of eye position.

  12. Blue-blocking IOLs decrease photoreception without providing significant photoprotection.

    PubMed

    Mainster, Martin A; Turner, Patricia L

    2010-01-01

    Violet and blue light are responsible for 45% of scotopic, 67% of melanopsin, 83% of human circadian (melatonin suppression) and 94% of S-cone photoreception in pseudophakic eyes (isoilluminance source). Yellow chromophores in blue-blocking intraocular lenses (IOLs) eliminate between 43 and 57% of violet and blue light between 400 and 500 nm, depending on their dioptric power. This restriction adversely affects pseudophakic photopic luminance contrast, photopic S-cone foveal threshold, mesopic contrast acuity, scotopic short-wavelength sensitivity and circadian photoreception. Yellow IOL chromophores provide no tangible clinical benefits in exchange for the photoreception losses they cause. They fail to decrease disability glare or improve contrast sensitivity. Most epidemiological evidence shows that environmental light exposure and cataract surgery are not significant risk factors for the progression of age-related macular degeneration (AMD). Thus, the use of blue-blocking IOLs is not evidence-based medicine. Most AMD occurs in phakic adults over 60 years of age, despite crystalline lens photoprotection far greater than that of blue-blocking IOLs. Therefore, if light does play some role in the pathogenesis of AMD, then 1) senescent crystalline lenses do not prevent it, so neither can blue-blocking IOLs that offer far less photoprotection, and 2) all pseudophakes should wear sunglasses in bright environments. Pseudophakes have the freedom to remove their sunglasses for optimal photoreception whenever they choose to do so, provided that they are not encumbered permanently by yellow IOL chromophores. In essence, yellow chromophores are placebos for prevention of AMD that permanently restrict a pseudophake's dim light and circadian photoreception at ages when they are needed most. If yellow IOLs had been the standard of care, then colorless UV-blocking IOLs could be advocated now as "premium" IOLs because they offer dim light and circadian photoreception roughly 15

  13. Facts About Pink Eye

    MedlinePlus

    ... occur in both eyes and often accompanies a common cold or respiratory tract infection. Laboratory tests usually are not needed to diagnose ... by using artificial tears for the dryness and cold packs for the inflammation. ... neonatorum. Common symptoms include eye discharge and puffy, red eyelids ...

  14. Photorefraction of the Eye

    ERIC Educational Resources Information Center

    Colicchia, Giuseppe; Wiesner, Hartmut; Zollman, Dean

    2015-01-01

    Photorefraction is a method to easily estimate the refractive state of the eye. The principle of photorefraction involves projecting light into the eye during flash photography and then examining the paths of light that emerge from the pupil after scattering on the back portion of the interior of the eyeball (fundus). We will explain the optical…

  15. Photorefraction of the Eye

    ERIC Educational Resources Information Center

    Colicchia, Giuseppe; Wiesner, Hartmut; Zollman, Dean

    2015-01-01

    Photorefraction is a method to easily estimate the refractive state of the eye. The principle of photorefraction involves projecting light into the eye during flash photography and then examining the paths of light that emerge from the pupil after scattering on the back portion of the interior of the eyeball (fundus). We will explain the optical…

  16. Understanding pink eye

    USDA-ARS?s Scientific Manuscript database

    Pink eye (PE) is a physiological tuber disorder that can result in serious processing complications and storage losses. The earliest external symptoms consist of an ephemeral pinkish discoloration around tuber eyes, predominately at the bud end of the tuber. These pinkish areas can then develop into...

  17. An Eye for Learning.

    ERIC Educational Resources Information Center

    Ostwald, Thomas

    1995-01-01

    Presents a hands-on activity as an excellent starting point for investigations related to the eye. Involves making a simple model of the vertebrate eye to illustrate the formation of an upside-down image on the retina by the lens. Links to investigations in numerous science disciplines including astronomy, genetics, biology, earth science, and…

  18. An Eye for Learning.

    ERIC Educational Resources Information Center

    Ostwald, Thomas

    1995-01-01

    Presents a hands-on activity as an excellent starting point for investigations related to the eye. Involves making a simple model of the vertebrate eye to illustrate the formation of an upside-down image on the retina by the lens. Links to investigations in numerous science disciplines including astronomy, genetics, biology, earth science, and…

  19. The questionably dry eye.

    PubMed Central

    Mackie, I. A.; Seal, D. V.

    1981-01-01

    This paper is concerned with the recognition of the dry eye when the clinical diagnosis is in doubt and other external eye diseases may be present. Papillary conjunctivitis is common to the dry eye as well as other pathological conditions and confuses the diagnosis. We have correlated the factors involved in the assessment for dryness. We have shown that particulate matter in the unstained tear film is associated with low tear lysozyme concentration. Tear flow and tear lysozyme are not necessarily interrelated, but a low lysozyme concentration (tear lysozyme ratio < 1.0) is associated with keratoconjunctivitis sicca. The Schirmer I test can produce false positive results, and we have suggested a modification to overcome this. This modified test will detect the eye with severely depleted lysozyme secretion, but it is unreliable for detecting the eye with moderately depleted secretion. We find that its lowest normal limit should be considered as 6 mm. Images PMID:7448154

  20. Dermocystidium sp. infection in Blue Ridge Sculpin captured in Maryland

    USGS Publications Warehouse

    Blazer, Vicki; Hitt, Nathaniel P.; Snyder, Craig D.; Snook, Erin; Adams, Cynthia

    2016-01-01

    Raised pale cysts were observed on Blue Ridge Sculpin Cottus caeruleomentum during stream fish community surveys in Catoctin Mountain Park, Maryland. When examined histologically, preserved sculpin exhibited multiple cysts containing spherical endospores with a refractile central body characteristic of Dermocystidiumspp. Cysts were not observed on the gills or internally. The portion of the watershed in which affected sculpin were observed contained lower than expected numbers of sculpin, raising concerns about the population effects of this infection. A nearby stream lacked sculpin even though they are common in this region, further suggesting the possibility of regional effects. This is the first report of a Dermocystidium infecting any fish species in the eastern United States.

  1. Jupiter in blue, ultraviolet and near infrared

    NASA Technical Reports Server (NTRS)

    2000-01-01

    These three images of Jupiter, taken through the narrow angle camera of NASA's Cassini spacecraft from a distance of 77.6 million kilometers (48.2 million miles) on October 8, reveal more than is apparent to the naked eye through a telescope.

    The image on the left was taken through the blue filter. The one in the middle was taken in the ultraviolet. The one on the right was taken in the near infrared.

    The blue-light filter is within the part of the electromagnetic spectrum detectable by the human eye. The appearance of Jupiter in this image is, consequently, very familiar. The Great Red Spot (below and to the right of center) and the planet's well-known banded cloud lanes are obvious. The brighter bands of clouds are called zones and are probably composed of ammonia ice particles. The darker bands are called belts and are made dark by particles of unknown composition intermixed with the ammonia ice.

    Jupiter's appearance changes dramatically in the ultraviolet and near infrared images. These images are near negatives of each other and illustrate the way in which observations in different wavelength regions can reveal different physical regimes on the planet.

    All gases scatter sunlight efficiently at short wavelengths; this is why the sky appears blue on Earth. The effect is even more pronounced in the ultraviolet. The gases in Jupiter's atmosphere, above the clouds, are no different. They scatter strongly in the ultraviolet, making the deep banded cloud layers invisible in the middle image. Only the very high altitude haze appears dark against the bright background. The contrast is reversed in the near infrared, where methane gas, abundant on Jupiter but not on Earth, is strongly absorbing and therefore appears dark. Again the deep clouds are invisible, but now the high altitude haze appears relatively bright against the dark background. High altitude haze is seen over the poles and the equator.

    The Great Red Spot, prominent in all images, is

  2. Jupiter in blue, ultraviolet and near infrared

    NASA Technical Reports Server (NTRS)

    2000-01-01

    These three images of Jupiter, taken through the narrow angle camera of NASA's Cassini spacecraft from a distance of 77.6 million kilometers (48.2 million miles) on October 8, reveal more than is apparent to the naked eye through a telescope.

    The image on the left was taken through the blue filter. The one in the middle was taken in the ultraviolet. The one on the right was taken in the near infrared.

    The blue-light filter is within the part of the electromagnetic spectrum detectable by the human eye. The appearance of Jupiter in this image is, consequently, very familiar. The Great Red Spot (below and to the right of center) and the planet's well-known banded cloud lanes are obvious. The brighter bands of clouds are called zones and are probably composed of ammonia ice particles. The darker bands are called belts and are made dark by particles of unknown composition intermixed with the ammonia ice.

    Jupiter's appearance changes dramatically in the ultraviolet and near infrared images. These images are near negatives of each other and illustrate the way in which observations in different wavelength regions can reveal different physical regimes on the planet.

    All gases scatter sunlight efficiently at short wavelengths; this is why the sky appears blue on Earth. The effect is even more pronounced in the ultraviolet. The gases in Jupiter's atmosphere, above the clouds, are no different. They scatter strongly in the ultraviolet, making the deep banded cloud layers invisible in the middle image. Only the very high altitude haze appears dark against the bright background. The contrast is reversed in the near infrared, where methane gas, abundant on Jupiter but not on Earth, is strongly absorbing and therefore appears dark. Again the deep clouds are invisible, but now the high altitude haze appears relatively bright against the dark background. High altitude haze is seen over the poles and the equator.

    The Great Red Spot, prominent in all images, is

  3. Ural Mountains, Russia

    NASA Image and Video Library

    2015-10-06

    This image from NASA Terra spacecraft shows the Ural Mountains, which run 2500 km north-south through western Russia, and form the boundary between Europe and Asia. Since the 17th century, the mountains were exploited for their deposits of iron, copper, gold, coal, oil, mica and gemstones. The Urals are among the world's oldest existing mountain ranges, having been formed about 275 million years ago due to the collision of the Laurussia supercontinent with the continent of Kazakhstania. The image was acquired July 13, 2011, covers an area of 39 by 62 km, and is located near 65.5 degrees north, 59.9 degrees east. http://photojournal.jpl.nasa.gov/catalog/PIA19795

  4. Three-dimensional modeling of blue jets and blue starters

    NASA Astrophysics Data System (ADS)

    Pasko, V. P.; George, J. J.

    2001-12-01

    Blue jets are narrow cones of blue light propagating upward from the apparent cloud tops at speeds of the order of 100 km/s to a terminal altitude of about 40 km [Wescott et al., GRL, 22, 1209, 1995]. Blue starters are distinguished from blue jets by a much lower terminal altitude. They protrude upward from the cloud top (17-18 km) to a maximum 25.5 km in altitude [Wescott et al., GRL, 23, 2153, 1996]. It has recently been suggested that blue jets correspond qualitatively to the development of the streamer zone of a positive leader and therefore should be filled with a branching structure of streamer channels [Petrov and Petrova, Tech. Phys., 44, 472, 1999]. In our talk we will discuss the physical concept proposed by Petrov and Petrova [1999] as well as will demonstrate a role of blue jets and blue starters in the large-scale atmospheric electric circuit. We will also discuss specific physical reasons and required circumstances for occurrence of blue jets and starters above thundercloud tops and will support our arguments with results from a new three-dimensional model. The model simulates the propagation of branching streamer channels constituting blue jets and starters as a three dimensional growth of fractal trees in a self-consistent electric field created by thundercloud charges. The model is based on a phenomenological probabilistic approach proposed in [Niemeyer et al., IEEE Trans. Electr. Insul., 24, 309, 1989] and is a straightforward expansion of the previously developed two-dimensional version [Pasko et al., GRL, 27, 497, 2000]. The model results indicate that blue jets and starters can be formed by a fast ( ~1 sec) accumulation of 110-150 C of positive thundercloud charge distributed in a volume with effective radius 3 km near the cloud top at 15 km. The obtained results closely resemble characteristics of blue jets and blue starters observed by Wescott et al. [1995; 1996] in terms of their altitude extents, transverse dimensions and conical structure

  5. Rotational Loading of Double-Braid Line Eye Splices.

    DTIC Science & Technology

    1982-06-01

    Development Center It. Cot,,,,, of G,.eto. Avery Point Groton , CT 06340 12. T ,,,p . R ,. ..n. P.... C.... 12. -Soopseein g ,,’ M o,,,, , .S~ s...eye of a line under tension is rotated around a bollard as might occur during a docking operation. The Blue Book splice-(-*) method, used on double...braid line before 1976, is thought to have one leg of the eye that is significantly weaker than the other. The Red Book splice--*) method, a revision of

  6. Mountain Home Well - Photos

    DOE Data Explorer

    Shervais, John

    2012-01-11

    The Snake River Plain (SRP), Idaho, hosts potential geothermal resources due to elevated groundwater temperatures associated with the thermal anomaly Yellowstone-Snake River hotspot. Project HOTSPOT has coordinated international institutions and organizations to understand subsurface stratigraphy and assess geothermal potential. Over 5.9km of core were drilled from three boreholes within the SRP in an attempt to acquire continuous core documenting the volcanic and sedimentary record of the hotspot: (1) Kimama, (2) Kimberly, and (3) Mountain Home. The Mountain Home drill hole is located along the western plain and documents older basalts overlain by sediment. Data submitted by project collaborator Doug Schmitt, University of Alberta

  7. STRAWBERRY MOUNTAIN WILDERNESS, OREGON.

    USGS Publications Warehouse

    Thayer, T.P.; Stotelmeyer, Ronald B.

    1984-01-01

    The Strawberry Mountain Wilderness extends 18 mi along the crest of the Strawberry Range and comprises about 53 sq mi in the Malheur National Forest, Grant County, Oregon. Systematic geologic mapping, geochemical sampling and detailed sampling of prospect workings was done. A demonstrated copper resource in small quartz veins averaging at most 0. 33 percent copper with traces of silver occurs in shear zones in gabbro. Two small areas with substantiated potential for chrome occur near the northern edge of the wilderness. There is little promise for the occurrence of additional mineral or energy resources in the Strawberry Mountain Wilderness.

  8. WILSON MOUNTAINS WILDERNESS, COLORADO.

    USGS Publications Warehouse

    Bromfield, Calvin S.; Williams, Frank E.

    1984-01-01

    The Wilson Mountains Wilderness consists of about 68 sq mi in the San Miguel Mountains in southwestern Colorado. Based on a mineral survey two areas in the wilderness have a probable mineral-resource potential. One area is on the east margin of the area in the Trout Lake mining district, and the other is near the center of the area, the Mount Wilson mining district. Both areas have had a modest base and (or) precious metal production from narrow veins and have a probable potential for the occurrence of similar deposits. Of more significance is a probable mineral-resource potential for disseminated copper mineralization in the Mount Wilson mining district.

  9. Himalayan Mountain Range, India

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Snow is present the year round in most of the high Himalaya Mountain Range (33.0N, 76.5E). In this view taken at the onset of winter, the continuous snow line can be seen for hundreds of miles along the south face of the range in the Indian states of Punjab and Kashmir. The snow line is at about 12,000 ft. altitude but the deep Cenab River gorge is easily delineated as a break along the south edge of the snow covered mountains. '

  10. Flood Frequenices and Bridge and Culvert Sizes for Forested Mountains of North Carolina

    Treesearch

    James E. Douglass

    1974-01-01

    A method is presented for predicting flood discharge from the forested Blue Ridge Mountains of North Carolina for storms at recurrence intervals of 2.33, 5, 10, 20, 30, 40, and 50 years. These predictions are based on area and maximum elevation of the drainage. Once storm discharge has been estimated, the proper size of culvert can be determined from tables which list...

  11. Bark beetle-induced forest mortality in the North American Rocky Mountains

    Treesearch

    Kevin Hyde; Scott Peckham; Tom Holmes; Brent Ewers

    2016-01-01

    The epidemic of mortality by insects and disease throughout the Northern American Rocky Mountains exceeds previous records both in severity and spatial extent. Beetle attacks weaken trees and introduce blue-stain fungi that induce hydraulic failure leading to mortality. The magnitude of this outbreak spurs predictions of major changes to...

  12. P gene as an inherited biomarker of human eye color.

    PubMed

    Rebbeck, Timothy R; Kanetsky, Peter A; Walker, Amy H; Holmes, Robin; Halpern, Allan C; Schuchter, Lynn M; Elder, David E; Guerry, DuPont

    2002-08-01

    Human pigmentation, including eye color, has been associated with skin cancer risk. The P gene is the human homologue to the mouse pink-eye dilution locus and is responsible for oculocutaneous albinism type 2 and other phenotypes that confer eye hypopigmentation. The P gene is located on chromosome 15q11.2-q12, which is also the location of a putative eye pigmentation gene (EYCL3) inferred to exist by linkage analysis. Therefore, the P gene is a strong candidate for determination of human eye color. Using a sample of 629 normally pigmented individuals, we found that individuals were less likely to have blue or gray eyes if they had P gene variants Arg305Trp (P = 0.002), Arg419Gln (P = 0.001), or the combination of both variants (P = 0.003). These results suggest that P gene, in part, determines normal phenotypic variation in human eye color and may therefore represent an inherited biomarker of cutaneous cancer risk.

  13. Mineral resources of the Whipple Mountains and Whipple Mountains Addition Wilderness Study Areas, San Bernardino County, California

    USGS Publications Warehouse

    Marsh, Sherman P.; Raines, Gary L.; Diggles, Michael F.; Howard, Keith A.; Simpson, Robert W.; Hoover, Donald B.; Ridenour, James; Moyle, Phillip R.; Willett, Spencee L.

    1988-01-01

    ) decorative building stone are located at the Stewart mine, New American Eagle mine, Turk Silver mine, Twin Lode mine, decorative stone property, Lucky Green group, Blue Cloud mine, Nickel Plate mine, Crescent mine, Quadrangle Copper group, and the Copper Basin mine. The Whipple Mountains Addition Wilderness Study Area has moderate resource potential for copper, gold, and silver resources and low resource potential for sand and gravel and other rock products. There is no resource potential for oil and gas or for geothermal energy in the Whipple Mountains Addition Wilderness Study Area. Although there are no identified resources in the Whipple Mountains Addition Wilderness Study Area, sites within and immediately adjacent warrant further study because of gold assays from widespread, numerous samples.

  14. Pluto’s Blue Haze

    NASA Image and Video Library

    The sky on Pluto is blue! Kind of. This is Pluto in an Minute. So it’s not exactly the case that the sky on Pluto is blue, rather, what the New Horizons science team has found in recent images do...

  15. Blue Origin Facility - Construction Progress

    NASA Image and Video Library

    2017-03-21

    Construction is progressing on Blue Origin's 750,000-square-foot facility being built at Exploration Park on NASA Kennedy Space Center property in Florida. Blue Origin will use the factory to manufacture its two-stage super-heavy-lift New Glenn launch vehicle and launch the vehicles from Space Launch Complex 46 at Cape Canaveral Air Force Station.

  16. Cyanoacrylate Adhesives in Eye Wounds.

    DTIC Science & Technology

    EYE, *WOUNDS AND INJURIES), (*ADHESIVES, EYE), (*ACRYLIC RESINS, ADHESIVES), CORNEA , HEALING, TISSUES(BIOLOGY), TOLERANCES(PHYSIOLOGY), NECROSIS, SURGICAL SUPPLIES, STRENGTH(PHYSIOLOGY), SURGERY, THERAPY

  17. Advocacy for eye care.

    PubMed

    Ravilla, Thulasiraj D; Ramasamy, Dhivya

    2012-01-01

    The effectiveness of eye care service delivery is often dependant on how the different stakeholders are aligned. These stakeholders range from the ministries of health who have the capacity to grant government subsidies for eye care, down to the primary healthcare workers who can be enrolled to screen for basic eye diseases. Advocacy is a tool that can help service providers draw the attention of key stakeholders to a particular area of concern. By enlisting the support, endorsement and participation of a wider circle of players, advocacy can help to improve the penetration and effectiveness of the services provided. There are several factors in the external environmental that influence the eye care services - such as the availability of trained manpower, supply of eye care consumables, government rules and regulations. There are several instances where successful advocacy has helped to create an enabling environment for eye care service delivery. Providing eye care services in developing countries requires the support - either for direct patient care or for support services such as producing trained manpower or for research and dissemination. Such support, in the form of financial or other resources, can be garnered through advocacy.

  18. [Study on the safety of blue light leak of LED].

    PubMed

    Shen, Chong-Yu; Xu, Zheng; Zhao, Su-Ling; Huang, Qing-Yu

    2014-02-01

    In this paper, the blue light properties of LED illumination devices have been investigated. Against the status quo of China's LED lighting, we measured the spectrum component of LED lamps and analyzed the photobiological safety under the current domestic and international standards GB/T 20145-2006/CIE S009/E: 2002 and IEC62471: 2006 standards as well as CTL-0744_2009-laser resolution, which provides the reference to the manufacture of LED lighting lamps as well as related safety standards and laws. If the radiance intensity of blue light in LED is lower than 100 W x m(-2) x Sr(-1), there is no harm to human eyes. LEDs will not cause harm to human eyes under normal use, but we should pay attention to the protection of special populations (children), and make sure that they avoid looking at a light source for a long time. The research has found that the blue-rich lamps can affect the human rule of work and rest, and therefore, the LED lamps with color temperature below 4 000 K and color rendering index of 80 are suitable for indoor use. At the same time, the lamps with different parameters should be selected according to the different distances.

  19. Blues You Can Use: Teaching the Faust Theme through Music, Literature, and Film.

    ERIC Educational Resources Information Center

    Copeland, Matt; Goering, Chris

    2003-01-01

    Uses the blues to teach the universal Faust theme, which was a common motif expressed in many lyrics coming out of the Mississippi Delta region in the United States during the 1920s and 1930s. Uses this opportunity to open students' eyes to a musical form often overlooked and misinterpreted in mainstream culture, and to improve students' critical…

  20. CATS EYES Adjustment Procedures

    DTIC Science & Technology

    1993-04-01

    AL-TR-1 993-0025 AD-A264 069 CATS EYES ADJUSTMENT PROCEDURES A R M Joseph C. Antonio DTIC S ELECTET University of Dayton Research Institute MAY 13...Final November 1992 - January 1993 4. TITLE AND SUBTITLE S. FUNDING NUMBERS C F33615-90-C-0005 CATS EYES Adjustment Procedures PE - 62205F 6. AUTHOR(S) PR...the loss of NVG performance resulting from improper goggle adjustments. This report describes correct adjustment procedures for the CATS EYES NVG system

  1. Personal identification by eyes.

    PubMed

    Marinović, Dunja; Njirić, Sanja; Coklo, Miran; Muzić, Vedrana

    2011-09-01

    Identification of persons through the eyes is in the field of biometrical science. Many security systems are based on biometric methods of personal identification, to determine whether a person is presenting itself truly. The human eye contains an extremely large number of individual characteristics that make it particularly suitable for the process of identifying a person. Today, the eye is considered to be one of the most reliable body parts for human identification. Systems using iris recognition are among the most secure biometric systems.

  2. Eye movement tics.

    PubMed Central

    Shawkat, F; Harris, C M; Jacobs, M; Taylor, D; Brett, E M

    1992-01-01

    An 8-year-old girl presented with opsoclonus-like eye movement and an 18 month history of intermittent facial tics. Investigations were all normal. Electro-oculography showed the eye movements to be of variable amplitude (10-40 degrees), with no intersaccadic interval, and with a frequency of 3-4 Hz. Saccades, smooth pursuit, optokinetic, and vestibular reflexes were all normal. These abnormal eye movements eventually disappeared. It is thought that they were a form of ocular tics. PMID:1477052

  3. Eye-Safe Lidar

    NASA Technical Reports Server (NTRS)

    Byer, Robert L.

    1989-01-01

    Laser infrared radar (lidar) undergoing development harmless to human eyes, consists almost entirely of solid-state components, and offers high range resolution. Operates at wavelength of about 2 micrometers. If radiation from such device strikes eye, almost completely absorbed by cornea without causing damage, even if aimed directly at eye. Continuous-wave light from laser oscillator amplified and modulated for transmission from telescope. Small portion of output of oscillator fed to single-mode fiber coupler, where mixed with return pulses. Intended for remote Doppler measurements of winds and differential-absorption measurements of concentrations of gases in atmosphere.

  4. Risk aversion affects economic values of blue fox breeding scheme.

    PubMed

    Peura, J; Kempe, R; Strandén, I; Rydhmer, L

    2016-12-01

    The profit and production of an average Finnish blue fox farm was simulated using a deterministic bio-economic farm model. Risk was included using Arrow-Prat absolute risk aversion coefficient and profit variance. Risk-rated economic values were calculated for pregnancy rate, litter loss, litter size, pelt size, pelt quality, pelt colour clarity, feed efficiency and eye infection. With high absolute risk aversion, economic values were lower than with low absolute risk aversion. Economic values were highest for litter loss (18.16 and 26.42 EUR), litter size (13.27 and 19.40 EUR), pregnancy (11.99 and 18.39 EUR) and eye infection (12.39 and 13.81 EUR). Sensitivity analysis showed that selection pressure for improved eye health depended strongly on proportion of culled animals among infected animals and much less on the proportion of infected animals. The economic value of feed efficiency was lower than expected (6.06 and 8.03 EUR). However, it was almost the same magnitude as pelt quality (7.30 and 7.30 EUR) and higher than the economic value of pelt size (3.37 and 5.26 EUR). Risk factors should be considered in blue fox breeding scheme because they change the relative importance of traits.

  5. Trypan blue-assisted posterior capsulorhexis in pediatric cataract surgery

    PubMed Central

    Lotfy, Ayman; Abdelrahman, Ayman

    2017-01-01

    Purpose To evaluate the safety and efficacy of staining the posterior capsule with trypan blue during capsulorhexis in pediatric cataract surgery. Patients and methods This was a prospective randomized comparative study carried out at Alpha Vision Center, Zagazig, Egypt. This study included 2 groups of children with pediatric cataract randomly allocated to undergo irrigation and aspiration. In the trypan group, which included 11 eyes, trypan blue was used to stain the posterior capsule during posterior capsulorhexis. In the control group, which included 10 eyes, no staining was performed. All surgeries were performed by the same surgeon. The 2 groups were compared for criteria such as completion of capsulorhexis, disruption of vitreous face and in-the-bag intraocular lens implantation. Results This study included 21 eyes of 16 patients (age range: 6 months–4 years). A statistically significant difference was observed for the following parameters between the 2 groups: capsulorhexis completion (P=0.04), vitreous face disruption (P=0.01) and in-the-bag intraocular lens implantation (P=0.022). Conclusion This study suggests that staining of the posterior capsule during capsulorhexis in pediatric cataract operation gives better results than capsulorhexis without staining. The stain changes the capsule texture making capsulorhexis easier with fewer complications. PMID:28182152

  6. Autologous serum eye drops for dry eye

    PubMed Central

    Pan, Qing; Angelina, Adla; Zambrano, Andrea; Marrone, Michael; Stark, Walter J; Heflin, Thomas; Tang, Li; Akpek, Esen K

    2014-01-01

    Background Theoretically, autologous serum eye drops (AS) have a potential advantage over traditional therapies based on the assumption that AS serve not only as a lacrimal substitute to provide lubrication, but also contain other biochemical components mimicking natural tears more closely. The application of AS in dry eye treatment has gained popularity as a second-line therapy in the treatment of dry eye. Published studies on the subject indicate that autologous serum could be an effective treatment for dry eye. Objectives To evaluate the efficacy and safety of AS compared to artificial tears for treating dry eye. Search methods We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2013, Issue 3), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLD MEDLINE, (January 1950 to April 2013), EMBASE (January 1980 to April 2013), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to April 2013), the meta Register of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We also searched the Science Citation Index Expanded database (September 2013) and reference lists of included studies. We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 15 April 2013. Selection criteria We included randomized controlled trials (RCTs) in which AS was compared to artificial tears in the treatment of dry eye in adults. Data collection and analysis Two review authors independently screened all titles and abstracts and assessed full-text articles of potentially eligible trials. Two review authors extracted data and assessed the methodological quality and characteristics of the included trials.We contacted investigators for missing data

  7. Autologous serum eye drops for dry eye.

    PubMed

    Pan, Qing; Angelina, Adla; Zambrano, Andrea; Marrone, Michael; Stark, Walter J; Heflin, Thomas; Tang, Li; Akpek, Esen K

    2013-08-27

    =Theoretically, autologous serum eye drops (AS) have a potential advantage over traditional therapies based on the assumption that ASserve not only as a lacrimal substitute to provide lubrication, but also contain other biochemical components mimicking natural tears more closely. The application of AS in dry eye treatment has gained popularity as a second-line therapy in the treatment of dry eye.Published studies on the subject indicate that autologous serum could be an effective treatment for dry eye. To evaluate the efficacy and safety of AS compared to artificial tears for treating dry eye. We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2013, Issue 3),Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE,(January 1950 to April 2013), EMBASE (January 1980 to April 2013), Latin American and Caribbean Literature on Health Sciences(LILACS) (January 1982 to April 2013), themetaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov(www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We also searched the Science Citation Index Expanded database (September 2013) and reference lists of included studies. We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 15 April 2013. We included randomized controlled trials (RCTs) in which AS was compared to artificial tears in the treatment of dry eye in adults. Two review authors independently screened all titles and abstracts and assessed full-text articles of potentially eligible trials. Two review authors extracted data and assessed the methodological quality and characteristics of the included trials.We contacted investigators for missing data. For both primary and secondary outcomes, we reported mean differences with corresponding 95

  8. Rocky Mountain Spotted Fever.

    PubMed

    Phillips, Jennan

    2017-01-01

    The tick-borne disease Rocky Mountain spotted fever (RMSF) can have deadly outcomes unless treated appropriately, yet nonspecific flu-like symptoms complicate diagnosis. Occupational health nurses must have a high index of suspicion with symptomatic workers and recognize that recent recreational or occupational activities with potential tick exposure may suggest RMSF.

  9. Mountain pine beetle

    Treesearch

    Ken Gibson; Sandy Kegley; Barbara Bentz

    2009-01-01

    The mountain pine beetle, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae, Scolytinae) is a member of a group of insects known as bark beetles. Its entire life cycle is spent beneath the bark of host trees, except when adults emerge from brood trees and fly in search of new host trees.

  10. DOE's Yucca Mountain Studies.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC.

    This booklet is about the disposal of high-level nuclear waste in the United States with a particular focus on Yucca Mountain, Nevada as a repository site. Intended for readers who do not have a technical background, the booklet discusses why scientists and engineers think high-level nuclear waste may be disposed of safely underground. An…

  11. The Strongest Mountain

    ERIC Educational Resources Information Center

    Monnes, Colleen

    2004-01-01

    The article describes an activity for the author's fifth-grade students called "build the strongest mountain." To them, it was not a lesson--it was a challenge. To the author, it was an activity that turned a run-of-the-mill Earth science unit into a terrific opportunity for students to demonstrate their knowledge of erosion and develop…

  12. DOE's Yucca Mountain Studies.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC.

    This booklet is about the disposal of high-level nuclear waste in the United States with a particular focus on Yucca Mountain, Nevada as a repository site. Intended for readers who do not have a technical background, the booklet discusses why scientists and engineers think high-level nuclear waste may be disposed of safely underground. An…

  13. The Strongest Mountain

    ERIC Educational Resources Information Center

    Monnes, Colleen

    2004-01-01

    The article describes an activity for the author's fifth-grade students called "build the strongest mountain." To them, it was not a lesson--it was a challenge. To the author, it was an activity that turned a run-of-the-mill Earth science unit into a terrific opportunity for students to demonstrate their knowledge of erosion and develop…

  14. Rocky Mountain Riparian Digest

    Treesearch

    Deborah M. Finch

    2008-01-01

    The Rocky Mountain Riparian Digest presents the many facets of riparian research at the station. Included are articles about protecting the riparian habitat, the social and economic values of riparian environments, watershed restoration, remote sensing tools, and getting kids interested in the science.

  15. Rocky Mountain High.

    ERIC Educational Resources Information Center

    Hill, David

    2001-01-01

    Describes Colorado's Eagle Rock School, which offers troubled teens a fresh start by transporting them to a tuition- free campus high in the mountains. The program encourages spiritual development as well as academic growth. The atmosphere is warm, loving, structured, and nonthreatening. The article profiles several students' experiences at the…

  16. The Mountaineer Minority

    ERIC Educational Resources Information Center

    Egerton, John; Gaillard, Frye

    1974-01-01

    Discusses the new Appalachian movement, based on the assumption that mountain people are a distinct and maligned cultural minority; the people of Appalachia, white, black and red, have begun to strike back against the dam-builders, strip-miners, and others they say are gouging out the region's mineral resources by the cheapest means possible no…

  17. Klamath Mountains bioregion

    Treesearch

    Carl N. Skinner; Alan H. Taylor; James K. Agee

    2006-01-01

    The Klamath Mountains bioregion makes up a major portion of northwestern California continuing into southwestern Oregon to near Roseburg. In California, the bioregion lies primarily between the Northern California Coast bioregion on the west and the southern Cascade Range to the east. The southern boundary is made up of the Northern California Coast Ranges and Northern...

  18. The Mountaineer Minority

    ERIC Educational Resources Information Center

    Egerton, John; Gaillard, Frye

    1974-01-01

    Discusses the new Appalachian movement, based on the assumption that mountain people are a distinct and maligned cultural minority; the people of Appalachia, white, black and red, have begun to strike back against the dam-builders, strip-miners, and others they say are gouging out the region's mineral resources by the cheapest means possible no…

  19. Mountain-Plains Curriculum.

    ERIC Educational Resources Information Center

    Mountain-Plains Education and Economic Development Program, Inc., Glasgow AFB, MT.

    The document lists the Mountain-Plains curriculum by job title (where applicable), including support courses. The curriculum areas covered are mathematics skills, communication skills, office education, lodging services, food services, marketing and distribution, welding support, automotive, small engines, career guidance, World of Work, health…

  20. Mountain-Plains Curriculum.

    ERIC Educational Resources Information Center

    Mountain-Plains Education and Economic Development Program, Inc., Glasgow AFB, MT.

    The document lists the Mountain-Plains curriculum by job title (where applicable), including support courses. The curriculum areas covered are mathematics skills, communication skills, office education, lodging services, food services, marketing and distribution, welding support, automotive, small engines, career guidance, World of Work, health…

  1. Magnetic eye tracking in mice.

    PubMed

    Payne, Hannah L; Raymond, Jennifer L

    2017-09-05

    Eye movements provide insights about a wide range of brain functions, from sensorimotor integration to cognition; hence, the measurement of eye movements is an important tool in neuroscience research. We describe a method, based on magnetic sensing, for measuring eye movements in head-fixed and freely moving mice. A small magnet was surgically implanted on the eye, and changes in the magnet angle as the eye rotated were detected by a magnetic field sensor. Systematic testing demonstrated high resolution measurements of eye position of <0.1°. Magnetic eye tracking offers several advantages over the well-established eye coil and video-oculography methods. Most notably, it provides the first method for reliable, high-resolution measurement of eye movements in freely moving mice, revealing increased eye movements and altered binocular coordination compared to head-fixed mice. Overall, magnetic eye tracking provides a lightweight, inexpensive, easily implemented, and high-resolution method suitable for a wide range of applications.

  2. Digital mountains: toward development and environment protection in mountain regions

    NASA Astrophysics Data System (ADS)

    Jiang, Xiaobo

    2007-06-01

    Former studies on mountain system are focused on the department or subject characters, i.e. different department and branches of learning carry out researches only for their individual purposes and with individual characters of the subject of interests. As a whole, their investigation is lacking of comprehensive study in combination with global environment. Ecological environment in mountain regions is vulnerable to the disturbance of human activities. Therefore, it is a key issue to coordinate economic development and environment protection in mountain regions. On the other hand, a lot of work is ongoing on mountain sciences, especially depending on the application of RS and GIS. Moreover, the development of the Digital Earth (DE) provides a clue to re-understand mountains. These are the background of the emergence of the Digital Mountains (DM). One of the purposes of the DM is integrating spatial related data and information about mountains. Moreover, the DM is a viewpoint and methodology of understanding and quantifying mountains holistically. The concept of the DM is that, the spatial and temporal data related to mountain regions are stored and managed in computers; moreover, manipulating, analyzing, modeling, simulating and sharing of the mountain information are implemented by utilizing technologies of RS, GIS, GPS, Geo-informatic Tupu, computer, virtual reality (VR), 3D simulation, massive storage, mutual operation and network communication. The DM aims at advancing mountain sciences and sustainable mountain development. The DM is used to providing information and method for coordinating the mountain regions development and environment protection. The fundamental work of the DM is the design of the scientific architecture. Furthermore, construct and develop massive databases of mountains are the important steps these days.

  3. Corrected color glasses for effective protection of eyes

    NASA Astrophysics Data System (ADS)

    Ciosek, Jerzy

    2001-08-01

    The subject of modern and save sunglasses is entertaining to many people especially due to anti-UV eye protection. Many people use glasses with anti-UV or blue-block coatings to driving or sun-tanning. There were analyzed transmittance and reflectance of different sunglasses made with thin-layer coatings. Sunglasses with absorption-interference protection are specially interesting due to technical simplicity of production.

  4. Autologous serum eye drops for dry eye.

    PubMed

    Pan, Qing; Angelina, Adla; Marrone, Michael; Stark, Walter J; Akpek, Esen K

    2017-02-28

    Theoretically, autologous serum eye drops (AS) offer a potential advantage over traditional therapies on the assumption that AS not only serve as a lacrimal substitute to provide lubrication but contain other biochemical components that allow them to mimic natural tears more closely. Application of AS has gained popularity as second-line therapy for patients with dry eye. Published studies on this subject indicate that autologous serum could be an effective treatment for dry eye. We conducted this review to evaluate the efficacy and safety of AS given alone or in combination with artificial tears as compared with artificial tears alone, saline, placebo, or no treatment for adults with dry eye. We searched CENTRAL (which contains the Cochrane Eyes and Vision Trials Register) (2016, Issue 5), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to July 2016), Embase (January 1980 to July 2016), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to July 2016), the ISRCTN registry (www.isrctn.com/editAdvancedSearch), ClinicalTrials.gov (www.clinicaltrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We also searched the Science Citation Index Expanded database (December 2016) and reference lists of included studies. We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 5 July 2016. We included randomized controlled trials (RCTs) that compared AS versus artificial tears for treatment of adults with dry eye. Two review authors independently screened all titles and abstracts and assessed full-text reports of potentially eligible trials. Two review authors extracted data and assessed risk of bias and characteristics of included trials. We contacted investigators to ask for missing data. For both primary and

  5. Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching.

    PubMed

    Grimm, C; Wenzel, A; Williams, T; Rol, P; Hafezi, F; Remé, C

    2001-02-01

    Acute white-light damage to rods depends on the amount of rhodopsin available for bleaching during light exposure. Bleached rhodopsin is metabolically regenerated through the visual cycle involving the pigment epithelium, or photochemically by deep blue light through photoreversal of bleaching. Because photoreversal is faster than metabolic regeneration of rhodopsin by several orders of magnitude, the photon catch capacity of the retina is significantly augmented during blue-light illumination, which may explain the greater susceptibility of the retina to blue light than to green light. However, blue light can also affect function of several blue-light-absorbing enzymes that may lead to the induction of retinal damage. Therefore, this study was conducted to test whether rhodopsin and its bleaching intermediates play a role in blue-light-induced retinal degeneration. Eyes of anesthetized rats and mice that did or did not contain rhodopsin were exposed to green (550 +/- 10 nm) or deep blue (403 +/- 10 nm) light for up to 2 hours. Rats with nearly rhodopsinless retinas were obtained by bleaching rhodopsin in animals with inhibited metabolic rhodopsin regeneration-that is, under halothane anesthesia. In addition, Rpe65(-/-) mice that are completely without rhodopsin were used to test the susceptibility to blue-light damage of a rodent retina completely devoid of the visual pigment. Effects of illumination on photoreceptor morphology were assessed 24 hours or 10 days thereafter by morphologic and biochemical methods. Exposure to blue light resulted in severe retinal damage and activation of the transcription factor AP-1 in rats. In contrast, green light had no effect. When rhodopsin was almost completely bleached by short-term green-light exposure while metabolic regeneration (but not photoreversal) was prevented by halothane anesthesia, blue-light exposure induced distinct lesions in rat retinas. When both metabolic rhodopsin regeneration and photoreversal of bleaching

  6. Cassidy eye exam

    NASA Image and Video Library

    2013-07-11

    ISS036-E-018262 (11 July 2013) --- NASA astronaut Chris Cassidy, Expedition 36 flight engineer, performs a visual exam using an eye chart (out of frame) in the Destiny laboratory of the International Space Station.

  7. Cassidy eye exam

    NASA Image and Video Library

    2013-07-11

    ISS036-E-018265 (11 July 2013) --- NASA astronaut Chris Cassidy, Expedition 36 flight engineer, performs a visual exam using an eye chart (out of frame) in the Destiny laboratory of the International Space Station.

  8. Cat-Eyed Saturn

    NASA Image and Video Library

    2006-04-13

    Bright, high altitude clouds, like those imaged here, often appear more filamentary or streak-like than clouds imaged at slightly deeper levels in Saturn atmosphere. This view also shows one of the many cat eye vortices.

  9. Common Eye Disorders

    MedlinePlus

    ... Click here to see demonstration ) Top of Page Cataract Cataract is a clouding of the eye’s lens and ... cause of vision loss in the United States. Cataracts can occur at any age because of a ...

  10. Pink Eye (Conjunctivitis)

    MedlinePlus

    ... E (IgE). This antibody triggers special cells called mast cells in the mucous lining of your eyes and ... reactions, such as a combination of antihistamines and mast cell stabilizers Drugs that help control inflammation, such as ...

  11. Eye Injuries (For Parents)

    MedlinePlus

    ... the eyelid. Others, like those that happen during sports activities, can be serious and require medical attention. Signs and Symptoms redness stinging or burning watering sensitivity to light blurred vision swelling of the eyelids discoloration around the eye ...

  12. Eyes, Bulging (Proptosis)

    MedlinePlus

    ... them know what to expect during the evaluation. Warning signs In people with bulging eyes, certain symptoms ... child When to see a doctor People with warning signs should see a doctor as soon as ...

  13. Smoking and Eye Health

    MedlinePlus

    ... that is most common in women after menopause. Smoking increases the risk of serious vision loss in people with other eye diseases. And when women smoke during pregnancy they are more likely to give birth prematurely, ...

  14. Dry eye syndrome

    MedlinePlus

    ... of dry eyes include: Dry environment or workplace (wind, air conditioning) Sun exposure Smoking or second-hand ... NOT smoke and avoid second-hand smoke, direct wind, and air conditioning. Use a humidifier, especially in ...

  15. Eye Disease Simulations

    MedlinePlus

    ... NIH Campus Mission Statement As part of the federal government’s National Institutes of Health (NIH), the National Eye ... National Institutes of Health (NIH) and is the Federal government’s lead agency for vision research that leads to ...

  16. Healthy Eyes, Healthy Body

    MedlinePlus

    ... to solving the problem of obesity within a generation, so that children born today will grow up ... letsmove.gov/ America’s move to raise a healthier generation of kids. EyeCare America http://www.eyecareamerica.org ...

  17. Amblyopia: Lazy Eye Symptoms

    MedlinePlus

    ... Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center Global Ophthalmology Guide Academy Publications EyeNet Ophthalmology Information for: International Ophthalmologists Media Medical Students Patients and Public Technicians and Nurses ...

  18. Using Eye Makeup

    MedlinePlus

    ... Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center Global Ophthalmology Guide Academy Publications EyeNet Ophthalmology Information for: International Ophthalmologists Media Medical Students Patients and Public Technicians and Nurses ...

  19. Amblyopia: Lazy Eye Diagnosis

    MedlinePlus

    ... Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center Global Ophthalmology Guide Academy Publications EyeNet Ophthalmology Information for: International Ophthalmologists Media Medical Students Patients and Public Technicians and Nurses ...

  20. Amblyopia: Lazy Eye Treatment

    MedlinePlus

    ... Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center Global Ophthalmology Guide Academy Publications EyeNet Ophthalmology Information for: International Ophthalmologists Media Medical Students Patients and Public Technicians and Nurses ...