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Sample records for blue nile abay

  1. Building Climate Resilience in the Blue Nile/Abay Highlands: A Role for Earth System Sciences

    PubMed Central

    Zaitchik, Benjamin F.; Simane, Belay; Habib, Shahid; Anderson, Martha C.; Ozdogan, Mutlu; Foltz, Jeremy D.

    2012-01-01

    The Blue Nile (Abay) Highlands of Ethiopia are characterized by significant interannual climate variability, complex topography and associated local climate contrasts, erosive rains and erodible soils, and intense land pressure due to an increasing population and an economy that is almost entirely dependent on smallholder, low-input agriculture. As a result, these highland zones are highly vulnerable to negative impacts of climate variability. As patterns of variability and precipitation intensity alter under anthropogenic climate change, there is concern that this vulnerability will increase, threatening economic development and food security in the region. In order to overcome these challenges and to enhance sustainable development in the context of climate change, it is necessary to establish climate resilient development strategies that are informed by best-available Earth System Science (ESS) information. This requirement is complicated by the fact that climate projections for the Abay Highlands contain significant and perhaps irreducible uncertainties. A critical challenge for ESS, then, is to generate and to communicate meaningful information for climate resilient development in the context of a highly uncertain climate forecast. Here we report on a framework for applying ESS to climate resilient development in the Abay Highlands, with a focus on the challenge of reducing land degradation. PMID:22470302

  2. Building climate resilience in the Blue Nile/Abay Highlands: a role for Earth system sciences.

    PubMed

    Zaitchik, Benjamin F; Simane, Belay; Habib, Shahid; Anderson, Martha C; Ozdogan, Mutlu; Foltz, Jeremy D

    2012-02-01

    The Blue Nile (Abay) Highlands of Ethiopia are characterized by significant interannual climate variability, complex topography and associated local climate contrasts, erosive rains and erodible soils, and intense land pressure due to an increasing population and an economy that is almost entirely dependent on smallholder, low-input agriculture. As a result, these highland zones are highly vulnerable to negative impacts of climate variability. As patterns of variability and precipitation intensity alter under anthropogenic climate change, there is concern that this vulnerability will increase, threatening economic development and food security in the region. In order to overcome these challenges and to enhance sustainable development in the context of climate change, it is necessary to establish climate resilient development strategies that are informed by best-available Earth System Science (ESS) information. This requirement is complicated by the fact that climate projections for the Abay Highlands contain significant and perhaps irreducible uncertainties. A critical challenge for ESS, then, is to generate and to communicate meaningful information for climate resilient development in the context of a highly uncertain climate forecast. Here we report on a framework for applying ESS to climate resilient development in the Abay Highlands, with a focus on the challenge of reducing land degradation.

  3. Building climate resilience in the Blue Nile/Abay Highlands: Part II-arole for earth system sciences

    USDA-ARS?s Scientific Manuscript database

    The Blue Nile (Abay) Highlands of Ethiopia are characterized by significant interannual climate variability, dissected topography and associated local climate contrasts, erosive rains and erodible soils, and intense land pressure due to an increasing population and an economy that is almost entirely...

  4. Building climate resilience in the Blue Nile/Abay Highlands: a framework for action.

    PubMed

    Simane, Belay; Zaitchik, Benjamin F; Mesfin, Desalegn

    2012-02-01

    Ethiopia has become warmer over the past century and human induced climate change will bring further warming over the next century at unprecedented rates. On the average, climate models show a tendency for higher mean annual rainfall and for wetter conditions, in particular during October, November and December, but there is much uncertainty about the future amount, distribution, timing and intensity of rainfall. Ethiopia's low level of economic development, combined with its heavy dependence on agriculture and high population growth rate make the country particularly susceptible to the adverse effects of climate change. Nearly 90% of Ethiopia's population lives in the Highlands, which include the critical Blue Nile (Abay) Highlands--a region that holds special importance due to its role in domestic agricultural production and international water resources. A five year study of climate vulnerability and adaptation strategies in communities of Choke Mountain, located in the center of the Abay Highlands, has informed a proposed framework for enhancing climate resilience in communities across the region. The framework is motivated by the critical need to enhance capacity to cope with climate change and, subsequently, to advance a carbon neutral and climate resilient economy in Ethiopia. The implicit hypothesis in applying a research framework for this effort is that science-based information, generated through improved understanding of impacts and vulnerabilities of local communities, can contribute to enhanced resilience strategies. We view adaptation to climate change in a wider context of changes, including, among others, market conditions, the political-institutional framework, and population dynamics. From a livelihood perspective, culture, historical settings, the diversity of income generation strategies, knowledge, and education are important factors that contribute to adaptive capacities. This paper reviews key findings of the Choke Mountain study, describes

  5. Building Climate Resilience in the Blue Nile/Abay Highlands: A Framework for Action

    PubMed Central

    Simane, Belay; Zaitchik, Benjamin F.; Mesfin, Desalegn

    2012-01-01

    Ethiopia has become warmer over the past century and human induced climate change will bring further warming over the next century at unprecedented rates. On the average, climate models show a tendency for higher mean annual rainfall and for wetter conditions, in particular during October, November and December, but there is much uncertainty about the future amount, distribution, timing and intensity of rainfall. Ethiopia’s low level of economic development, combined with its heavy dependence on agriculture and high population growth rate make the country particularly susceptible to the adverse effects of climate change. Nearly 90% of Ethiopia’s population lives in the Highlands, which include the critical Blue Nile (Abay) Highlands—a region that holds special importance due to its role in domestic agricultural production and international water resources. A five year study of climate vulnerability and adaptation strategies in communities of Choke Mountain, located in the center of the Abay Highlands, has informed a proposed framework for enhancing climate resilience in communities across the region. The framework is motivated by the critical need to enhance capacity to cope with climate change and, subsequently, to advance a carbon neutral and climate resilient economy in Ethiopia. The implicit hypothesis in applying a research framework for this effort is that science-based information, generated through improved understanding of impacts and vulnerabilities of local communities, can contribute to enhanced resilience strategies. We view adaptation to climate change in a wider context of changes, including, among others, market conditions, the political-institutional framework, and population dynamics. From a livelihood perspective, culture, historical settings, the diversity of income generation strategies, knowledge, and education are important factors that contribute to adaptive capacities. This paper reviews key findings of the Choke Mountain study

  6. Hydrological Response to Climate Change for Gilgel Abay River, in the Lake Tana Basin - Upper Blue Nile Basin of Ethiopia

    PubMed Central

    Dile, Yihun Taddele; Berndtsson, Ronny; Setegn, Shimelis G.

    2013-01-01

    Climate change is likely to have severe effects on water availability in Ethiopia. The aim of the present study was to assess the impact of climate change on the Gilgel Abay River, Upper Blue Nile Basin. The Statistical Downscaling Tool (SDSM) was used to downscale the HadCM3 (Hadley centre Climate Model 3) Global Circulation Model (GCM) scenario data into finer scale resolution. The Soil and Water Assessment Tool (SWAT) was set up, calibrated, and validated. SDSM downscaled climate outputs were used as an input to the SWAT model. The climate projection analysis was done by dividing the period 2010-2100 into three time windows with each 30 years of data. The period 1990-2001 was taken as the baseline period against which comparison was made. Results showed that annual mean precipitation may decrease in the first 30-year period but increase in the following two 30-year periods. The decrease in mean monthly precipitation may be as much as about -30% during 2010-2040 but the increase may be more than +30% in 2070-2100. The impact of climate change may cause a decrease in mean monthly flow volume between -40% to -50% during 2010-2040 but may increase by more than the double during 2070-2100. Climate change appears to have negligible effect on low flow conditions of the river. Seasonal mean flow volume, however, may increase by more than the double and +30% to +40% for the Belg (small rainy season) and Kiremit (main rainy season) periods, respectively. Overall, it appears that climate change will result in an annual increase in flow volume for the Gilgel Abay River. The increase in flow is likely to have considerable importance for local small scale irrigation activities. Moreover, it will help harnessing a significant amount of water for ongoing dam projects in the Gilgel Abay River Basin. PMID:24250755

  7. Hydrological response to climate change for Gilgel Abay River, in the Lake Tana Basin -Upper Blue Nile Basin of Ethiopia.

    PubMed

    Dile, Yihun Taddele; Berndtsson, Ronny; Setegn, Shimelis G

    2013-01-01

    Climate change is likely to have severe effects on water availability in Ethiopia. The aim of the present study was to assess the impact of climate change on the Gilgel Abay River, Upper Blue Nile Basin. The Statistical Downscaling Tool (SDSM) was used to downscale the HadCM3 (Hadley centre Climate Model 3) Global Circulation Model (GCM) scenario data into finer scale resolution. The Soil and Water Assessment Tool (SWAT) was set up, calibrated, and validated. SDSM downscaled climate outputs were used as an input to the SWAT model. The climate projection analysis was done by dividing the period 2010-2100 into three time windows with each 30 years of data. The period 1990-2001 was taken as the baseline period against which comparison was made. Results showed that annual mean precipitation may decrease in the first 30-year period but increase in the following two 30-year periods. The decrease in mean monthly precipitation may be as much as about -30% during 2010-2040 but the increase may be more than +30% in 2070-2100. The impact of climate change may cause a decrease in mean monthly flow volume between -40% to -50% during 2010-2040 but may increase by more than the double during 2070-2100. Climate change appears to have negligible effect on low flow conditions of the river. Seasonal mean flow volume, however, may increase by more than the double and +30% to +40% for the Belg (small rainy season) and Kiremit (main rainy season) periods, respectively. Overall, it appears that climate change will result in an annual increase in flow volume for the Gilgel Abay River. The increase in flow is likely to have considerable importance for local small scale irrigation activities. Moreover, it will help harnessing a significant amount of water for ongoing dam projects in the Gilgel Abay River Basin.

  8. Sedimentation of the Triassic Jurassic Adigrat Sandstone Formation, Blue Nile (Abay) Basin, Ethiopia

    NASA Astrophysics Data System (ADS)

    Wolela, A.

    2008-09-01

    Exploration of oil and gas deposits in the Blue Nile Basin targeted the Adigrat Sandstone Formation as a reservoir objective. Conglomerates, gravely sandstones, coarse to medium-grained sandstones, very fine-grained cross-bedded sandstones, siltstones and mudstones of the Adigrat Sandstone Formation were deposited in semi-arid to arid climates. The North-western highlands are the main source for the sedimentation. The poorly-sorted, crudely-bedded conglomerates and gravely sandstones are interpreted as alluvial fan deposits. The basal polymictic orthoconglomerate passes up vertically into gravely sandstone, possibly indicating proximal to mid-fan sedimentation. The alluvial fan sedimentation passes up vertically into channel, point bars and flood-plain fines. The meandering river sedimentation is characterized by single and amalgamated multi-storey sandstone bodies. In places, the uppermost part of the Adigrat Sandstone Formation is represented by coal-bearing sediments possibly reflect lacustrine depositional environment. The medium-coarse-grained sandstone is a possible oil and gas reservoir, whilst the fine-grained sediments are a possible gas reservoir.

  9. Characterisation of stable isotopes to identify residence times and runoff components in two meso-scale catchments in the Abay/Upper Blue Nile basin, Ethiopia

    NASA Astrophysics Data System (ADS)

    Tekleab, S.; Wenninger, J.; Uhlenbrook, S.

    2014-06-01

    Measurements of the stable isotopes oxygen-18 (18O) and deuterium (2H) were carried out in two meso-scale catchments, Chemoga (358 km2) and Jedeb (296 km2) south of Lake Tana, Abay/Upper Blue Nile basin, Ethiopia. The region is of paramount importance for the water resources in the Nile basin, as more than 70% of total Nile water flow originates from the Ethiopian highlands. Stable isotope compositions in precipitation, spring water and streamflow were analysed (i) to characterise the spatial and temporal variations of water fluxes; (ii) to estimate the mean residence time of water using a sine wave regression approach; and (iii) to identify runoff components using classical two-component hydrograph separations on a seasonal timescale. The results show that the isotopic composition of precipitation exhibits marked seasonal variations, which suggests different sources of moisture generation for the rainfall in the study area. The Atlantic-Indian Ocean, Congo basin, Upper White Nile and the Sudd swamps are the potential moisture source areas during the main rainy (summer) season, while the Indian-Arabian and Mediterranean Sea moisture source areas during little rain (spring) and dry (winter) seasons. The spatial variation in the isotopic composition is influenced by the amount effect as depicted by moderate coefficients of determination on a monthly timescale (R2 varies from 0.38 to 0.68) and weak regression coefficients (R2 varies from 0.18 to 0.58) for the altitude and temperature effects. A mean altitude effect accounting for -0.12‰/100 m for 18O and -0.58‰/100 m for 2H was discernible in precipitation isotope composition. Results from the hydrograph separation on a seasonal timescale indicate the dominance of event water, with an average of 71 and 64% of the total runoff during the wet season in the Chemoga and Jedeb catchments, respectively. Moreover, the stable isotope compositions of streamflow samples were damped compared to the input function of

  10. Visualising DNA in Classrooms Using Nile Blue

    ERIC Educational Resources Information Center

    Milne, Christine; Roche, Scott; McKay, David

    2008-01-01

    Giving students the opportunity to extract, manipulate and visualise DNA molecules enhances a constructivist approach to learning about modern techniques in biology and biotechnology Visualisation usually requires agarose gel electrophoresis and staining. In this article, we report on an alternative DNA stain, Nile Blue A, that may be used in the…

  11. Visualising DNA in Classrooms Using Nile Blue

    ERIC Educational Resources Information Center

    Milne, Christine; Roche, Scott; McKay, David

    2008-01-01

    Giving students the opportunity to extract, manipulate and visualise DNA molecules enhances a constructivist approach to learning about modern techniques in biology and biotechnology Visualisation usually requires agarose gel electrophoresis and staining. In this article, we report on an alternative DNA stain, Nile Blue A, that may be used in the…

  12. Nile Blue derivatives as lysosomotropic photosensitizers

    NASA Astrophysics Data System (ADS)

    Lin, Chi-Wei; Shulok, Janine R.; Kirley, S. D.; Cincotta, Louis; Foley, James W.

    1991-06-01

    The benzophenoxazines, including several Nile blue analogues, are a unique group of dyes that localize selectively in animal tumors. Chemical modifications of Nile blue A can yield derivatives with high 1O2 quantum yields. These derivatives represent a group of potentially effective photosensitizers for selective phototherapy of malignant tumors. In vitro evaluation of these derivatives has indicated that those with high 1O2 yields are very effective in mediating the photocytotoxicity of tumor cells. This photodynamic effect is most likely mediated through the action of 1O2, since photoirradiation under D2O enhanced and under hypoxic conditions diminished the photocytotoxic action. The subcellular localization of these photosensitizers in bladder tumor cells in culture was examined by light and fluorescence microscopies as well as by histochemical and biochemical studies. The results indicate that these dyes are localized primarily in the lysosome. The cellular uptake and retention of these dyes is energy- and pH-dependent. Agents such as nigericin, which alter the transmembrane pH gradient, reduced uptake and enhanced efflux of the dyes, while agents such as valinomycin, which reduce cellular membrane potential, had no effect on the uptake. These findings are consistent with having ion-trapping as the mechanism for the uptake of these dyes. Photoirradiation of sensitizer-treated cells obliterated lysosomes in a light-dose and drug-dose dependent fashion. Release of the hydrolytic enzymes may be the main cause for subsequent cell death since the cytolytic effect was reduced by a specific inhibitor of lysosomal proteolytic enzyme. A lysosomotropic photosensitization mechanism is therefore proposed for the photocytotoxic action of the Nile blue derivatives. This mechanism may provide an approach to the development of new photosensitizers for the effective and selective destruction of malignant tumors.

  13. Building hydrologic information systems to promote climate resilience in the Blue Nile/Abay higlands

    USDA-ARS?s Scientific Manuscript database

    Climate adaptation requires information about climate and land-surface conditions – spatially distributed, and at scales of human influence (the field scale). This article describes a project aimed at combining meteorological data, satellite remote sensing, hydrologic modeling, and downscaled clima...

  14. Ultrasound promoted synthesis of Nile Blue derivatives.

    PubMed

    Raju, B Rama; Sampaio, Diogo M F; Silva, M M; Coutinho, Paulo J G; Gonçalves, M Sameiro T

    2014-01-01

    Ultrasound irradiation was used for the first time towards the synthesis of new Nile Blue related benzo[a]phenoxazinium chlorides possessing isopentylamino, (2-cyclohexylethyl)amino and phenethylamino groups at 5-position of the heterocyclic system. The efficacy of sonochemistry was investigated with some of our earlier reported synthesis of benzo[a]phenoxazinium chlorides. This newer protocol proved competent in terms of reaction times and enhanced yields. Photophysical studies carried out in ethanol, water and simulated physiological conditions, revealed that emission maxima occurred in the range 644-656 nm, with high fluorescent quantum yields. Other attractive feature exhibited by these materials includes good thermal stability. These properties might be useful in the development of fluorescent probes for biotechnology. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. From non-covalent binding to irreversible DNA lesions: nile blue and nile red as photosensitizing agents

    NASA Astrophysics Data System (ADS)

    Gattuso, Hugo; Besancenot, Vanessa; Grandemange, Stéphanie; Marazzi, Marco; Monari, Antonio

    2016-06-01

    We report a molecular modeling study, coupled with spectroscopy experiments, on the behavior of two well known organic dyes, nile blue and nile red, when interacting with B-DNA. In particular, we evidence the presence of two competitive binding modes, for both drugs. However their subsequent photophysical behavior is different and only nile blue is able to induce DNA photosensitization via an electron transfer mechanism. Most notably, even in the case of nile blue, its sensitization capabilities strongly depend on the environment resulting in a single active binding mode: the minor groove. Fluorescence spectroscopy confirms the presence of competitive interaction modes for both sensitizers, while the sensitization via electron transfer, is possible only in the case of nile blue.

  16. From non-covalent binding to irreversible DNA lesions: nile blue and nile red as photosensitizing agents

    PubMed Central

    Gattuso, Hugo; Besancenot, Vanessa; Grandemange, Stéphanie; Marazzi, Marco; Monari, Antonio

    2016-01-01

    We report a molecular modeling study, coupled with spectroscopy experiments, on the behavior of two well known organic dyes, nile blue and nile red, when interacting with B-DNA. In particular, we evidence the presence of two competitive binding modes, for both drugs. However their subsequent photophysical behavior is different and only nile blue is able to induce DNA photosensitization via an electron transfer mechanism. Most notably, even in the case of nile blue, its sensitization capabilities strongly depend on the environment resulting in a single active binding mode: the minor groove. Fluorescence spectroscopy confirms the presence of competitive interaction modes for both sensitizers, while the sensitization via electron transfer, is possible only in the case of nile blue. PMID:27329409

  17. Temporal variability of hydroclimatic extremes in the Blue Nile basin

    NASA Astrophysics Data System (ADS)

    Taye, Meron Teferi; Willems, Patrick

    2012-03-01

    This paper examines the long-term historical changes in frequency and amplitude of hydroclimatic extremes in the Blue Nile basin using data from the second half of 20th century. The temporal variability of basin-wide rainfall extremes and river flow extremes from four gauging stations was investigated under the hypothesis of no trend and no persistence in time. On the basis of a quantile anomaly analysis method, decadal variations in extreme daily, monthly, and annual quantiles were studied, and the periods of statistical significance were identified. The analysis showed that high and low river flows and rainfall depths do not vary in time in a fully random way but show a particular variation pattern. Their extremes show significant decadal variations. The 1980s had statistically significant negative anomalies in extremes in comparison with the long-term reference period of 1964-2009, while the 1960s-1970s and the 1990s-2000s had positive anomalies, although less significant. There is neither consistent increasing nor decreasing trend in rainfall and flow extremes of recent years. Therefore, anticipated trends due to global warming could not be identified. Conversely, low-flow extremes show an increasing trend during the last decade, which could be related to the effect of water regulation works at the outlet of Lake Tana. Moreover, similar patterns and statistically significant correlations were found between climatic indices representing the Pacific and Atlantic Oceans and the Blue Nile rainfall and flow extremes. Changes that occur on the Pacific Ocean appear to be a main driver for the decadal oscillations in climate and related high and low Blue Nile water availability for Ethiopia, Sudan, and Egypt.

  18. Shale gas characterization of the Dinder and Blue Nile Formations in the Blue Nile Basin, East Sudan

    NASA Astrophysics Data System (ADS)

    Shoieb, Monera Adam; Sum, Chow Weng; Bhattachary, Swapan Kumar; Abidin, Nor Syazwani Zainal; Abdelrahim, Omer Babiker

    2016-11-01

    The development of gas and oil in unconventional plays in United State and Northern Europe has affected the finances and the energy security. Geochanical properties of shale rocks can have a major impact on the efficiency of shale gas exploration. The goal of this study is to evaluate shale gas potentiality in the Blue Nile Basin, using samples from existing drilled wells. All the samples were analyzed in detail with the following organic geochemical techniques: total organic carbon (TOC), Rock-eval pyrolysis, to determine the quality and quantity of the organic matter. The total organic carbon (TOC) values for the shale intervals vary from 0.6 to 4.5weight% in FARASHA-1 Well, while in TAWAKUL-1 Well range from 0.4 to 2.4weight%, suggesting that fair to good source generative potential, as revealed by the S2 v's TOC plot. Hydrogen index (HI) values range from 12 to 182 mg HC/g TOC in the two wells, indicating type III and IV derived-input in the samples and their potential to generate gas. However, the Blue Nile and Dinder Formation have Tmax values in the range of 437 to 456°C, indicating early maturity in the oil window. Thus, higher maturity levels have affected the hydrocarbon generation potential and HI of the samples.

  19. Hydrological characterization of watersheds in the Blue Nile Basin

    NASA Astrophysics Data System (ADS)

    Gebrehiwot, S. G.; Ilstedt, U.; Gärdenas, A. I.; Bishop, K.

    2010-07-01

    We made a hydrological characterization of 32 watersheds (31-4350 km2) in the Blue Nile Basin, using data from a study of water and land resources in the Blue Nile Basin, Ethiopia published in 1964 by the US Bureau of Reclamation (USBR). The USBR document contains data on flow, climate, topography, geology, soil type, and land use for the period from 1959 to 1963. The aim of the study was to identify which combination of watershed variables best explain the variation in the hydrological regime, with special focus to low flow and, what kind of land use low flow might benefit from. Principal Component Analysis (PCA) and Partial Least Square (PLS) were used to analyze the relationship between hydrologic variables (total flow, maximum flow, minimum flow, runoff coefficient, and low flow index) and 30 potential watershed variables. We found that three groups of watershed variables - climate and topography, geology and soil, and land use had almost equal influence on the variation in the hydrologic variables (R2 values ranging from 0.3 to 0.5). The individual variables which were selected based on statistical significance from all groups of explanatory variables were better in explaining the variation. Low flow was positively correlated most strongly to wetland, wood land, rainfall, luvisols, and alluvial soils. Low flow was negatively correlated to grazing land, bush land, tuffs/basalts, eutric-vertisols and riverine forest. We concluded that low flow benefits from the land use types that preserve soil quality and water storage, such as wetland, savannah and woodland, while it was lower in land use resulting in soil degradation. Therefore it provides support to the theory that some land use such as grassland, can promote higher low flow

  20. Scanning Electrochemical Microscopy of DNA Monolayers Modified with Nile Blue

    PubMed Central

    Gorodetsky, Alon A.; Hammond, William J.; Hill, Michael G.; Slowinski, Krzysztof; Barton, Jacqueline K.

    2009-01-01

    Scanning electrochemical microscopy (SECM) is used to probe long-range charge transport (CT) through DNA monolayers containing the redox-active Nile Blue (NB) intercalator covalently affixed at a specific location in the DNA film. At substrate potentials negative of the formal potential of covalently attached NB, the electrocatalytic reduction of Fe(CN)63− generated at the SECM tip is observed only when NB is located at the DNA/solution interface; for DNA films containing NB in close proximity to the DNA/electrode interface, the electrocatalytic effect is absent. This behavior is consistent with both rapid DNA-mediated CT between the NB intercalator and the gold electrode as well as a rate-limiting electron transfer between NB and the solution phase Fe(CN)63−. The DNA-mediated nature of the catalytic cycle is confirmed through sequence-specific and localized detection of attomoles of TATA-binding protein, a transcription factor that severely distorts DNA upon binding. Importantly, the strategy outlined here is general and allows for the local investigation of the surface characteristics of DNA monolayers both in the absence and in the presence of DNA binding proteins. These experiments highlight the utility of DNA-modified electrodes as versatile platforms for SECM detection schemes that take advantage of CT mediated by the DNA base pair stack. PMID:19053641

  1. Coordinating and Negotiating Blue Nile Water Resource Development

    NASA Astrophysics Data System (ADS)

    Geressu, R. T.; Harou, J. J.

    2016-12-01

    Many countries are proposing new reservoirs in transboundary river basins world-wide that impact downstream regions. Failure to consider and incorporate multiple stakeholder interests in system design and decision making could contribute to regional disputes. Negotiated introduction of new assets and associated coordination strategies (e.g. cost and power sharing arrangements) could reduce conflict and help achieve consensus. In multi-stakeholders problems, parties are likely to prioritize performance targets differently and hence will often prefer different water system designs, stalling negotiations. An ideal solution is where individual and group benefits are maximized by allocating (exchanging) resources according to the relative preferences of stakeholders. Hence, a negotiation support mechanism should be able to incorporate stakeholder preference information. In this paper, we propose a three-step search & deliberate, elicit preferences, and search & negotiate approach for supporting negotiations in complex infrastructure-environmental systems. The approach seeks to find designs and coordination mechanisms that are more beneficial than non-cooperative actions. The proposed approach is applied to a stylized Blue Nile reservoir design problem in Ethiopia seeking to set reservoir capacity and operating rules. We consider cost and energy performance metrics for Ethiopia and energy and irrigation water supply in Sudan. We use example stakeholder (i.e., Ethiopian and Sudanese) priorities for demonstration purpose. The result is an agreed system design and coordination schemes (co-financing and power trade). The application results demonstrate that incorporating coordination strategies, such as energy trade, cost sharing, and financing in assessing transboundary reservoir development options could help find compromise designs that different parties can support.

  2. Age and origin of the Gezira alluvial fan between the Blue and White Nile rivers

    NASA Astrophysics Data System (ADS)

    Williams, martin

    2014-05-01

    The Gezira is a low-angle alluvial fan bounded by the Blue Nile to the east and the White Nile to the west. It is the main agricultural region of Sudan and produces high quality long-staple cotton for export. Dark cracking clays (vertisols) cover much of the Gezira and range in age from 50 kyr to Holocene. The Gezira is traversed by a series of defunct sandy channels that originate between Sennar and Wad Medani on the present-day Blue Nile. With a radius of 300 km and an area of 40,000 km2 the Gezira is a mega-fan. The younger channels range in age from early Holocene to 100 kyr, while near surface channels filled with rolled quartz and carbonate gravels have ages back to >250 kyr. Boreholes in the Gezira reveal coarse alluvial sands and gravels in now buried channels overlain by alluvial clays, forming a repetitive sequence of fining-upwards alluvial units. that probably extend back to Pliocene times. The fan is up to 180 m thick with a volume of ~1,800 km3. The sandy or gravelly bed-load channels coincide with colder drier climates and sparse vegetation in the Ethiopian headwaters of the Blue Nile and the alluvial clays denote widespread flooding during times of stronger summer monsoon. The early stages of such flood events were often accompanied by mass burial of Nile oyster (Etheria elliptica) beds, such as the 45-50 kyr floods that deposited up to 5 m of clay in the northern Gezira. A unique feature of the eastern Gezira is a former Blue Nile channel at least 80 km long running parallel to the present river and entirely filled with volcanic ash. The channel was only 3-4 m deep and 20-30 m wide. Very fine laminations and cross-beds, together with locally abundant phytoliths and sponge spicules, suggest slow-moving water, with flow dispersed across many distributary channels. The ash geochemistry is similar to that in the lower part of the Kibish Formation in the lower Omo valley of southern Ethiopia and points to a minimum age of 100 kyr and a maximum age of

  3. Nile tilapia and blue tilapia fry production in a subtropical climate

    USDA-ARS?s Scientific Manuscript database

    The relationship between production in earthen ponds located in a subtropical climate of fry suitable for hormonal sex inversion and degree-days was quantified for Nile tilapia (Oreochromis niloticus; Egypt strain) and blue tilapia (O. aureus). Degree-days were calculated for each trial as the sum o...

  4. Causal links between Nile floods and eastern Mediterranean sapropel formation during the past 125 kyr confirmed by OSL and radiocarbon dating of Blue and White Nile sediments

    NASA Astrophysics Data System (ADS)

    Williams, M. A. J.; Duller, G. A. T.; Williams, F. M.; Woodward, J. C.; Macklin, M. G.; El Tom, O. A. M.; Munro, R. N.; El Hajaz, Y.; Barrows, T. T.

    2015-12-01

    It has long been hypothesised that beds of highly organic mud or sapropels seen in marine sediment cores retrieved from the floor of the eastern Mediterranean accumulated during times of high Nile fluvial discharge. Our recent fieldwork in the valleys of the Blue Nile, the White Nile and the main Nile has for the first time revealed a sequence of extreme flood episodes synchronous with sapropel units S5 (124 kyr), S4 (102 kyr), S3 (81 kyr), S2 (55 kyr) and S1 (13.5-6.5 kyr). There are more weakly defined links with Nile floods and sapropel units S9 (240 kyr), S8 (217 kyr), S7 (195 kyr), S6 (172 kyr), but the dating error terms are too large to allow us to be too definite. During times of extreme floods over the past 125 kyr, wide distributary channels of the Blue Nile flowed across the Gezira alluvial fan in central Sudan and transported a bed load of sand and gravel into the lower White Nile valley. The sands were reworked by wind to form source-bordering dunes, all of which contain heavy minerals of Ethiopian provenance. These source-bordering dunes were active at 115-105 kyr, 60 kyr and 12-7 kyr, all times of extreme Blue Nile floods. The flood and dune sediments were dated using a combination of optically stimulated luminescence (OSL) and radiocarbon analyses. The Quaternary record of Nile floods discussed here shows a precessional signal and reflects episodes of stronger summer monsoon and more northerly seasonal movement of the ITCZ, linked to times of higher insolation in northern tropical latitudes. Progressive aggradation of Holocene Nile channels in northern Sudan has had a profound influence upon human settlement in the last 8 kyr.

  5. Late Pleistocene desiccation of Lake Tana, source of the Blue Nile

    NASA Astrophysics Data System (ADS)

    Lamb, Henry F.; Bates, C. Richard; Coombes, Paul V.; Marshall, Michael H.; Umer, Mohammed; Davies, Sarah J.; Dejen, Eshete

    2007-02-01

    High-resolution seismic data from Lake Tana, the source of the Blue Nile in northern Ethiopia, reveal a deep sedimentary sequence divided by four strong reflectors. Data from nearshore cores show that the uppermost strong reflector represents a stiff silt unit, interpreted as a desiccation surface. Channel cuts in this surface, bordered by levee-like structures, are apparent in the seismic data from near the lake margin, suggesting fluvial downcutting and over-bank deposition during seasonal flood events. Periphytic diatoms and peat at the base of a core from the deepest part of the lake overlie compacted sediments, indicating that desiccation was followed by development of shallow-water environments and papyrus swamp in the central basin between 16,700 and 15,100 cal BP. As the lake level rose, open-water evaporation from the closed lake caused it to become slightly saline, as indicated by halophytic diatoms. An abrupt return to freshwater conditions occurred at 14,750 cal BP, when the lake overflowed into the Blue Nile. Further reflection surfaces with downcut structures are identifiable in seismic images of the overlying sediments, suggesting at least two lesser lake-level falls, tentatively dated to about 12,000 and 8000 cal BP. Since Lake Victoria, the source of the White Nile, was also dry until 15,000 cal BP, and did not reach overflow until 14,500 cal BP, the entire Nile system must have been reduced to intermittent seasonal flow until about 14,500 cal BP, when baseflow was re-established with almost simultaneous overflow of the headwater lakes of both the White and Blue Nile rivers. Desiccation of the Nile sources coincides with Heinrich event 1, when cessation of northward heat transport from the tropical Atlantic disrupted the Atlantic monsoon, causing drought in north tropical Africa. The strong reflectors at deeper levels in the seismic sequence of Lake Tana may represent earlier desiccation events, possibly contemporaneous with previous Late

  6. Runoff and precipitation dynamics in the Blue and White Nile catchments during the mid-Holocene: A data-model comparison

    NASA Astrophysics Data System (ADS)

    Blanchet, C. L.; Contoux, C.; Leduc, G.

    2015-12-01

    The Blue Nile is the major contributor of freshwater and sediments to the modern-day main Nile River and exerts a key control on seasonal flooding in the Nile valley. Recent studies have postulated that the relative contribution from the Blue Nile to the main Nile runoff might have been reduced during the mid-Holocene, at a time when higher boreal summer insolation stimulated enhanced precipitation in North Africa. Whether the decrease in the relative contribution from the Blue Nile resulted from a decrease in precipitation over the catchment, from an increase in White Nile runoff or from a combination of both is still a matter of debate. By comparing regional proxy-records with the output from a global atmospheric model zoomed on Africa, we propose that the reduced contribution from the Blue Nile at 6 ka originated from both a higher White Nile runoff and a lower Blue Nile runoff. Enhanced African and Indian monsoons at 6 ka induced a northern shift of the Intertropical Convergence Zone and an eastward shift of the Congo Air Boundary. Such an atmospheric configuration led to a negative anomaly of summer precipitation over the Blue Nile catchment that likely resulted in a reduction in the Blue Nile runoff. By contrast, a sustained positive anomaly of precipitation over the White Nile catchment during both summer and autumn most likely induced a higher main Nile runoff during the mid-Holocene. Using the model output, we propose a first synoptic view on regional rainfall dynamics that permits to reconcile contrasting proxy records.

  7. Using a Water Balance Model to Bound Potential Irrigation Development in the Upper Blue Nile Basin

    NASA Astrophysics Data System (ADS)

    Jain Figueroa, A.; McLaughlin, D.

    2016-12-01

    The Grand Ethiopian Renaissance Dam (GERD), on the Blue Nile is an example of water resource management underpinning food, water and energy security. Downstream countries have long expressed concern about water projects in Ethiopia because of possible diversions to agricultural uses that could reduce flow in the Nile. Such diversions are attractive to Ethiopia as a partial solution to its food security problems but they could also conflict with hydropower revenue from GERD. This research estimates an upper bound on diversions above the GERD project by considering the potential for irrigated agriculture expansion and, in particular, the availability of water and land resources for crop production. Although many studies have aimed to simulate downstream flows for various Nile basin management plans, few have taken the perspective of bounding the likely impacts of upstream agricultural development. The approach is to construct an optimization model to establish a bound on Upper Blue Nile (UBN) agricultural development, paying particular attention to soil suitability and seasonal variability in climate. The results show that land and climate constraints impose significant limitations on crop production. Only 25% of the land area is suitable for irrigation due to the soil, slope and temperature constraints. When precipitation is also considered only 11% of current land area could be used in a way that increases water consumption. The results suggest that Ethiopia could consume an additional 3.75 billion cubic meters (bcm) of water per year, through changes in land use and storage capacity. By exploiting this irrigation potential, Ethiopia could potentially decrease the annual flow downstream of the UBN by 8 percent from the current 46 bcm/y to the modeled 42 bcm/y.

  8. Using ENSO Indices to Enhance Long-Range Ensemble Streamflow Forecasts in The Blue Nile River

    NASA Astrophysics Data System (ADS)

    Habib, M. A.; Bradley, A.

    2012-12-01

    River forecasting centers around the globe have been using hydrologic ensemble forecast systems operationally. Better-enhanced forecasting systems are the ultimate need of the decision maker. This study proposes an enhancement technique for Long-Range Ensemble Streamflow Forecasts in The Blue Nile River. Many studies showed the link between summer rainfall and the large scale climate oscillations. Strong correlation is found between the El-Nino Southern Oscillations (ENSO) and annual flows in the Nile River at Diem on the Sudanese-Ethiopian boarders. Long-range streamflow forecasts produced by The Nile Forecast System at Ministry of Public Works and Irrigation in Egypt are used. Traditionally, baseline forecast weights each trace of the ensemble equally. In this study, we add an enhancement process to the forecasts by changing their weights depending on the correlation between the Streamflow and the ENSO indices (e.g. SST3.4, SOI). Weighting techniques using different distributions of the ENSO indices (e.g. Kernel, Gaussian) are examined. Diagnostic verification measures are used to evaluate this enhancement process.

  9. An electropolymerized Nile Blue sensing film-based nitrite sensor and application in food analysis.

    PubMed

    Chen, Xiaowei; Wang, Fang; Chen, Zilin

    2008-08-15

    This paper reports a poly-Nile Blue (PNB) sensing film based electrochemical sensor and the application in food analysis as a possible alternative for electrochemical detection of nitrite. The PNB-modified electrode in the sensor was prepared by in situ electropolymerization of Nile Blue at a prepolarized glassy carbon (GC) electrode and then characterized by cyclic voltammetry (CV) and pulse voltammetry in phosphate buffer (pH 7.1). Several key operational parameters affecting the electrochemical response of PNB sensing film were examined and optimized, such as polarization time, PNB film thickness and electrolyte pH values. As the electroactive PNB sensing film provides plenty of active sites for anodic oxidation of nitrite, the nitrite sensor exhibited high performance including high sensitivity, low detection limit, simple operation and good stability at the optimized conditions. The nitrite sensor revealed good linear behavior in the concentration range from 5.0x10(-7) mol L(-1) to 1.0x10(-4) mol L(-1) for the quantitative analysis of nitrite anion with a limit of detection of 1.0x10(-7) mol L(-1). Finally, the application in food analysis using sausage as testing samples was investigated and the results were consistent with those obtained by standard spectrophotometric method.

  10. The question of Sudan: a hydro-economic optimization model for the Sudanese Blue Nile

    NASA Astrophysics Data System (ADS)

    Satti, S.; Zaitchik, B.; Siddiqui, S.

    2015-05-01

    The effects of development and the uncertainty of a changing climate in eastern Africa pose myriad challenges for water managers along the Blue Nile. Sudan's large irrigation potential, hydroelectric dams, and prime location within the basin mean that Sudan's water management decisions will have great social, economic and political implications for the region. At the same time, Sudan's water use options are constrained by tradeoffs between upstream irrigation developments and downstream hydropower facilities as well as by the country's commitments under existing or future transboundary water sharing agreements. Here, we present a model that can be applied to evaluate optimal allocation of surface water resources to irrigation and hydropower in the Sudanese portion of the Blue Nile. Hydrologic inputs are combined with agronomic and economic inputs to formulate an optimization model within the General Algebraic Modeling System (GAMS). A sensitivity analysis is performed by testing model response to a range of economic conditions and to changes in the volume and timing of hydrologic flows. Results indicate that changing hydroclimate inputs have the capacity to greatly influence the productivity of Sudan's water resource infrastructure. Results also show that the economically optimal volume of water consumption, and thus the importance of existing treaty constraints, is sensitive to the perceived value of agriculture relative to electricity as well as to changing hydrological conditions.

  11. Modification of Blue LED using Organic-Inorganic Hybrid Polymer Doped with Nile Red for Artificial Lighting of Photosynthesis

    NASA Astrophysics Data System (ADS)

    Syakir, Norman; Syarifudin, Fahmi; Hidayat, Sahrul; Fitrilawati

    2017-07-01

    The photosynthesis process of chlorophyll absorbs only the light with wavelength in the blue and red ranges. The absorption peak of the chlorophyll-A is at 428 nm and 660 nm, while absorption peak of chlorophyll-B is at 453 nm and 643 nm. We report the modification of blue LED using hybrid polymer doped with Nile Red. In order to match the total absorption spectra of chlorophyll-A and chlorophyll-B, the emission spectrum of the modified blue LED was taken out by using the wavelength conversion material. We modified the blue LED by covering the blue LED of 450 nm as excitation source with precursor of red wavelength conversion material. The red wavelength conversion material was prepared by doped precursor of TMSPMA hybrid polymer with organic phosphor of Nile Red. The precursor of hybrid polymer was synthesized using sol-gel process and then it was doped with 0.1% Nile Red. In order to freeze the precursor of these conversion material, we employed UV photopolymerization process. The modified blue LED has two emission peaks, which are at 448 nm (blue emission) and at 651 nm (red emission). The optimum spectrum profile of the modified blue LED has similar range as the total absorption spectra of chlorophyll-A and chlorophyll-B that obtain using Nile Red with the mass of 2.9 μg and the driven current of 60 mA. This result has a potential application for the artificial lighting in the photosynthesis process of horticultures at indoor plantation.

  12. An outbreak of bovine trypanosomiasis in the Blue Nile State, Sudan

    PubMed Central

    2011-01-01

    Background In this paper, we report an outbreak of bovine trypanosomiasis in Kurmuk District, Blue Nile State, Sudan that involved an infection with four Trypanosoma species in cattle. The outbreak occurred in June 2010 when indigenous cattle, mainly Kenana and Fulani breed types, crossed the national Sudanese border to Ethiopia and returned. A veterinarian was notified of massive deaths in the cattle populations that recently came from Ethiopia. All animals involved in the outbreak were from the nomadic Fulani group and resident local cattle were not infected and no death has been reported among them. A total of 210 blood samples were collected from the ear vein of cattle. A few samples were also collected from other domestic animals species. Parasitological examinations including hematocrit centrifugation techniques (HCT) and Giemsa-stained thin blood films were carried out. ITS1-PCR, which provides a multi-species-specific diagnosis in a single PCR, was performed. Findings Parasitological examinations revealed that 43% (91/210) of the affected cattle population was infected with two morphologically distinct trypanosomes. Seventy animals (33.3%) were infected with T. vivax and twenty one (10%) with T. congolense. In contrast, ITS1-PCR was able to identify four Trypanosoma species namely T. vivax, T. congolense, T. simiae and T. brucei in 56.7% (80/141). T. brucei showed the highest prevalence of 36.9% (52/141) and the lowest 19% (27/141) was displayed by T. congolense. Furthermore, and because ITS1-PCR could not differentiate between T. brucei subspecies, serum resistance-associated (SRA) gene based PCR was used to detect the human T. brucei rhodesiense in T. brucei positive samples. None of the samples was shown positive for T. b. rhodesiense. The identity of the 400 bp PCR product originating from T. simiae, was further confirmed by sequencing and subsequent phylogenetic analysis. Conclusions The outbreak of bovine trypanosomiasis occurred in the Blue Nile

  13. Placental malaria and its effect on pregnancy outcomes in Sudanese women from Blue Nile State.

    PubMed

    Omer, Samia A; Idress, Hagir E; Adam, Ishag; Abdelrahim, Mutasim; Noureldein, Ali N; Abdelrazig, Abdelrahim M; Elhassan, Mohammed O; Sulaiman, Suad M

    2017-09-16

    Malaria infection during pregnancy can result in placental malaria and is associated with adverse pregnancy outcomes particularly among primigravidae. The aim of this study was to assess the prevalence and risk factors for placental malaria and its effect on pregnancy outcomes in Blue Nile state, Sudan. A cross-sectional hospital-based study was conducted consecutively during January 2012-December 2015 in three main hospitals in Blue Nile State, Sudan. At delivery, peripheral and placental blood samples were collected from consenting women. Finger prick blood was used for preparation of peripheral smears and for haemoglobin measurement. Smears were stained with Giemsa and examined microscopically for malaria parasites. Pregnancy outcomes in association to placental malaria were investigated. A total of 1149 mothers and their newborns were recruited. The mean (SD) of the age was 23.3 (5.2) years. Detection of malaria parasites was confirmed in 37.8% of the peripheral blood films and 59.3% of the placental films with Plasmodium falciparum as the only species detected. In multivariate analysis, younger age ≤23.2 years old (AOR = 3.2, 95% CI 1.9-5.5; P < 0.001), primiparae (AOR = 3.9, CI 2.1-7.6; P < 0.001), secundiparae (AOR = 2.8, 95% CI 1.5-5.1; P < 0.001, no antenatal care (ANC) visits (AOR = 11.9, 95% CI 7.8-18.1; P < 0.001) and not using bed nets (AOR = 3.5, 95% CI 1.7-6.8; P < 0.001) were risk factors for placental malaria. Education and residence were not associated with placental malaria infection. Placental malaria was significantly associated with maternal anaemia (AOR = 41.6, 95% CI 23.3-74.4; P < 0.001) and low birth weight (LBW) (AOR = 25.2, 95% CI 15.1-41.3; P < 0.001). During the study, there was a high prevalence of placental malaria in Blue Nile State-Sudan, as the enhanced control activities were not practiced, leading to adverse pregnancy outcomes, such as maternal anaemia and LBW.

  14. Nile blue fluorescence signals from cut single muscle fibers under voltage or current clamp conditions

    PubMed Central

    1978-01-01

    A method is presented for recording extrinsic optical signals from segments of single skeletal muscle fibers under current or voltage clamp conditions. Such segments, which are cut from intact fibers, are maintained in a relaxed state, while exhbiting otherwise normal physiological properties, including healthy delayed rectifier currents. Extrinsic fluorescence changes are demonstrated, using the permeant potentiometric probe, Nile Blue A. These changes vary nonlinearly with the controlled surface membrane potential, in a manner which suggests that they arise from potential changes in the sarcoplasmic reticulum. According to this interpretation, a simple model based on the gating charge movement implicated in excitation-contraction coupling, provides a self-consistent description of the voltage dependence of the signal that requires no additional parameters. PMID:310445

  15. Evaluation of regional climate model simulations of rainfall over the Upper Blue Nile basin

    NASA Astrophysics Data System (ADS)

    Alemseged, Tamiru Haile; Tom, Rientjes

    2015-07-01

    Climate change impact and adaptation studies can benefit from an enhanced understanding about the performance of individual as well as ensemble simulations of climate models. Studies that evaluate downscaled simulations of General Circulation Models (GCMs) by Regional Climate Models (RCMs) for African basins are noticeably missing. Recently, the Coordinated Regional Climate Downscaling Experiment (CORDEX) initiative has made multiple RCMs' outputs available for end users across the African continent. Before climate simulations receive applications in impact and adaptation studies, accuracy of the simulation results has to be evaluated. In this study, the rainfall accuracy of eight independent GCMs at a wide range of time scales over the Upper Blue Nile Basin (UBN) in Ethiopia is evaluated. The reference data for performance assessment was obtained from the rain gauge network of the National Meteorological Agency of Ethiopia (http://www.ethiomet.gov.et/)

  16. Personnel scheduling using an integer programming model- an application at Avanti Blue-Nile Hotels.

    PubMed

    Kassa, Biniyam Asmare; Tizazu, Anteneh Eshetu

    2013-01-01

    In this paper, we report perhaps a first of its kind application of management science in the Ethiopian hotel industry. Avanti Blue Nile Hotels, a newly established five star hotel in Bahir Dar, is the company for which we developed an integer programming model that determines an optimal weekly shift schedule for the Hotel's engineering department personnel while satisfying several constraints including weekly rest requirements per employee, rest requirements between working shifts per employee, required number of personnel per shift, and other constraints. The model is implemented on an excel solver routine. The model enables the company's personnel department management to develop a fair personnel schedule as needed and to effectively utilize personnel resources while satisfying several technical, legal and economic requirements. These encouraging achievements make us optimistic about the gains other Ethiopian organizations can amass by introducing management science approaches in their management planning and decision making systems.

  17. Climate Change Impact on Variability of Rainfall Intensity in Upper Blue Nile Basin, Ethiopia

    NASA Astrophysics Data System (ADS)

    Worku, L. Y.

    2015-12-01

    Extreme rainfall events are major problems in Ethiopia with the resulting floods that usually could cause significant damage to agriculture, ecology, infrastructure, disruption to human activities, loss of property, loss of lives and disease outbreak. The aim of this study was to explore the likely changes of precipitation extreme changes due to future climate change. The study specifically focuses to understand the future climate change impact on variability of rainfall intensity-duration-frequency in Upper Blue Nile basin. Precipitations data from two Global Climate Models (GCMs) have been used in the study are HadCM3 and CGCM3. Rainfall frequency analysis was carried out to estimate quantile with different return periods. Probability Weighted Method (PWM) selected estimation of parameter distribution and L-Moment Ratio Diagrams (LMRDs) used to find the best parent distribution for each station. Therefore, parent distributions for derived from frequency analysis are Generalized Logistic (GLOG), Generalized Extreme Value (GEV), and Gamma & Pearson III (P3) parent distribution. After analyzing estimated quantile simple disaggregation model was applied in order to find sub daily rainfall data. Finally the disaggregated rainfall is fitted to find IDF curve and the result shows in most parts of the basin rainfall intensity expected to increase in the future. As a result of the two GCM outputs, the study indicates there will be likely increase of precipitation extremes over the Blue Nile basin due to the changing climate. This study should be interpreted with caution as the GCM model outputs in this part of the world have huge uncertainty.

  18. Reservoir system expansion scheduling under conflicting interests - A Blue Nile application

    NASA Astrophysics Data System (ADS)

    Geressu, Robel; Harou, Julien

    2017-04-01

    New water resource developments are facing increasing resistance due to their real and perceived potential to affect existing systems' performance negatively. Hence, scheduling new dams in multi-reservoir systems requires considering conflicting performance objectives to minimize impacts, create consensus among wider stakeholder groups and avoid conflict. However, because of the large number of alternative expansion schedules, planning approaches often rely on simplifying assumptions such as the appropriate gap between expansion stages or less flexibility in reservoir release rules than what is possible. In this study, we investigate the extent to which these assumptions could limit our ability to find better performing alternatives. We apply a many-objective sequencing approach to the proposed Blue Nile hydropower reservoir system in Ethiopia to find best investment schedules and operating rules that maximize long-term discounted net benefits, downstream releases and energy generation during reservoir filling periods. The system is optimized using 30 realizations of stochastically generated streamflow data, statistically resembling the historical flow. Results take the form of Pareto-optimal trade-offs where each point on the curve or surface represents a combination of new reservoirs, their implementation dates and operating rules. Results show a significant relationship between detail in operating rule design (i.e., changing operating rules as the multi-reservoir expansion progresses) and the system performance. For the Blue Nile, failure to optimize operating rules in sufficient detail could result in underestimation of the net worth of the proposed investments by up to 6 billion USD if a development option with low downstream impact (slow filling of the reservoirs) is to be implemented.

  19. Effects of Bahir Dar Textile Factory Effluents on the Water Quality of the Head Waters of Blue Nile River, Ethiopia.

    PubMed

    Mehari, Abrehet Kahsay; Gebremedhin, Shewit; Ayele, Belayneh

    2015-01-01

    The study was conducted in 2013/14 with the objective of determining the effects of Bahir Dar textile factory effluents on the head of Blue Nile River water quality. Dissolve oxygen was higher at the upstream site of the river, whereas BOD5, TDS, and total alkalinity values were higher at wastewater outlet of the factory site. The mean values of dissolved oxygen, BOD5, and total alkalinity were above maximum permissible limits set by WHO for drinking water at head of Blue Nile River. The mean value of BOD5 was above permissible limit of IFC for textile effluents to be discharged to surface water. A total of 836 aquatic macroinvertebrate individuals belonging to 21 families were collected. The Shannon-Wiener Diversity Index, the Hilsenhoff family-level biotic index, family richness, and percent dipterans were calculated. Hilsenhoff family-level biotic index and percent dipterans metrics differed significantly among sampling sites (P < 0.05). Hilsenhoff family-level biotic index was higher at the most downstream site but percent dipterans were higher at site of discharge of effluent to the head of Blue Nile River. Therefore, there is indication that effluent demands frequent control and proper treatment before being discharged to the environment.

  20. Effects of Bahir Dar Textile Factory Effluents on the Water Quality of the Head Waters of Blue Nile River, Ethiopia

    PubMed Central

    Mehari, Abrehet Kahsay; Gebremedhin, Shewit; Ayele, Belayneh

    2015-01-01

    The study was conducted in 2013/14 with the objective of determining the effects of Bahir Dar textile factory effluents on the head of Blue Nile River water quality. Dissolve oxygen was higher at the upstream site of the river, whereas BOD5, TDS, and total alkalinity values were higher at wastewater outlet of the factory site. The mean values of dissolved oxygen, BOD5, and total alkalinity were above maximum permissible limits set by WHO for drinking water at head of Blue Nile River. The mean value of BOD5 was above permissible limit of IFC for textile effluents to be discharged to surface water. A total of 836 aquatic macroinvertebrate individuals belonging to 21 families were collected. The Shannon-Wiener Diversity Index, the Hilsenhoff family-level biotic index, family richness, and percent dipterans were calculated. Hilsenhoff family-level biotic index and percent dipterans metrics differed significantly among sampling sites (P < 0.05). Hilsenhoff family-level biotic index was higher at the most downstream site but percent dipterans were higher at site of discharge of effluent to the head of Blue Nile River. Therefore, there is indication that effluent demands frequent control and proper treatment before being discharged to the environment. PMID:26688685

  1. Permian and Triassic microfloral assemblages from the Blue Nile Basin, central Ethiopia

    NASA Astrophysics Data System (ADS)

    Dawit, Enkurie L.

    2014-11-01

    Palynological investigation was carried out on surface samples from up to 400 m thick continental siliciclastic sediments, here referred to as “Fincha Sandstone”, in the Blue Nile Basin, central Ethiopia. One hundred sixty species were identified from 15 productive samples collected along a continuous road-cut exposure. Six informal palynological assemblage zones have been identified. These assemblage zones, in ascending order, are: “Central Ethiopian Permian Assemblage Zone - CEPAZ I”, earliest Permian (Asselian-Sakmarian); “CEPAZ II”, late Early Permian (Artinskian-Kungurian); CEPAZ III - Late Permian (Kazanian-Tatarian); “CETAZ IV”, Lower Triassic (Olenekian Induan); “CETAZ V”, Middle Triassic (Anisian Ladinian); “CETAZ VI”, Late Triassic (Carnian Norian). Tentative age ranges proposed herein are compared with faunally calibrated palynological zones in Gondwana. The overall composition and vertical distribution of miospores throughout the studied section reveals a wide variation both qualitatively and quantitatively. The high frequency of monosaccate pollen in CEPAZ I may reflect a Glossopterid-dominated upland flora in the earliest Permian. The succeeding zone is dominated by straite/taeniate disaccate pollen and polyplicates, suggesting a notable increase in diversity of glossopterids. The decline in the diversity of taeniate disaccate pollen and the concomitant rise in abundance of non-taeniate disaccates in CEPAZ III may suggest the decline in Glossopteris diversity, though no additional evidence is available to equate this change with End-Permian extinction. More diverse and dominant non-taeniate, disaccate, seed fern pollen assignable to FalcisporitesAlisporites in CETAZ IV may represent an earliest Triassic recovery flora. The introduction of new disaccate forms with thick, rigid sacci, such as Staurosaccites and Cuneatisporites, in CETAZ V and VI may indicate the emergence of new gymnospermous plants that might have favourably

  2. Morphological changes of Gumara River channel over 50 years, upper Blue Nile basin, Ethiopia

    NASA Astrophysics Data System (ADS)

    Abate, Mengiste; Nyssen, Jan; Steenhuis, Tammo S.; Moges, Michael M.; Tilahun, Seifu A.; Enku, Temesgen; Adgo, Enyew

    2015-06-01

    In response to anthropogenic disturbances, alluvial rivers adjust their geometry. The alluvial river channels in the upper Blue Nile basin have been disturbed by human-induced factors since a longtime. This paper examines channel adjustment along a 38-km stretch of the Gumara River which drains towards Lake Tana and then to the Blue Nile. Over a 50 years period, agriculture developed rapidly in the catchment and flooding of the alluvial plain has become more frequent in recent times. The objectives of this study were to document the changes in channel planform and cross-section of the Gumara River and to investigate whether the changes could have contributed to the frequent flooding or vice versa. Two sets of aerial photographs (1957 and 1980) were scanned, and then orthorectified. Recent channel planform information was extracted from SPOT images of 2006 and Google Earth. Channel planform and bed morphology (vertical changes) were determined for these nearly 50 years period. The vertical changes were determined based on aggradation along a permanent structure, historic information on river cross-sections at a hydrological gauging station, and field observations. The results indicate that the lower reach of Gumara near its mouth has undergone major planform changes. A delta with approx. 1.12 km2 of emerged land was created between 1957 and 1980 and an additional 1 km2 of land has been added between 1980 and 2006. The sinuosity of the river changed only slightly: negatively (-1.1% i.e. meandering decreased) for the period from 1957 to 1980 and positively (+3.0%) for the period 1980-2006. Comparison of cross-sections at the hydrological gauging station showed that the deepest point in the river bed aggraded by 2.91 m for the period 1963-2009. The importance of sediment deposition in the stream and on its banks is related to land degradation in the upper catchment, and to artificial rising of Lake Tana level that creates a backwater effect and sediment deposition in

  3. Development of a Nile-blue based chemodosimeter for Hg2+ in aqueous solution and its application in biological imaging.

    PubMed

    Hu, Mingming; Yin, Jianhua; Li, Yahong; Zhao, Xiaofang

    2015-03-01

    A Nile blue-based chemodosimeter was newly synthesized. It can detect Hg(2+) in aqueous solution based on desulfurization reaction. Upon its addition into aqueous Hg(2+) ion solution, it exhibited a considerable blue-shift in its absorption and obvious fluorescence quenching. The detection mechanism was proved by mass spectrometry analysis and Gaussian calculations. Detection at an emission of 685 nm was extremely sensitive, with a detection limit of 2.5 × 10(-9) mol/L. The fluorescent images in living cells and zebrafish demonstrate its potential for studying the accumulation of mercury species in organism.

  4. Linking soil erosion to onsite financial cost: lessons from watersheds in the Blue Nile basin

    NASA Astrophysics Data System (ADS)

    Erkossa, T.; Wudneh, A.; Desalegn, B.; Taye, G.

    2015-02-01

    The study was conducted in three watersheds (Dapo, Meja and Mizewa) in the Ethiopian part of the Blue Nile Basin to estimate the onsite cost of soil erosion using the productivity change approach, in which crop yield reduction due to plant nutrients lost with the sediment and runoff has been analyzed. For this purpose, runoff measurement and sampling was conducted during the main rainy season of 2011 at the outlet of two to three sub watersheds in each watershed. The sediment concentration of the runoff, and nitrogen and phosphorus content of the runoff and sediment were determined. Crop response functions were developed for the two plant nutrients based on data obtained from the nearest Agricultural Research Centers. The response functions were used to estimate crop yield reduction as a result of the lost N and P assuming there is no compensation through fertilization. The results show a significant yield reduction and resultant financial loss to the farmers. Considering only grain yield of maize (Zea mays), farmers at Dapo annually lose about 220 and USD 150 ha-1 due to the loss of nitrogen and phosphorus, respectively. In view of the importance of the crop residues including as feed, the loss can be even greater. The study demonstrated that in addition to the long-term deterioration of land quality, the annual financial loss suffered by farmers is substantial. Therefore, on farm soil and water conservation measures that are suitable in biophysical and socio-economic terms in the landscapes and beyond need to be encouraged.

  5. Heterogeneous photocatalytic degradation of nile blue dye in aqueous BiOCl suspensions

    NASA Astrophysics Data System (ADS)

    Sarwan, Bhawna; Pare, B.; Acharya, A. D.

    2014-05-01

    Bismuth oxychloride (BiOCl) was synthesized by hydrolysis method. Several analytical tools such as X-ray diffraction, scanning electron microscopy, transmission electron microscopy, Brunauer-Emmett-Teller (BET) surface area, X-ray photoelectron spectroscopic, and energy-dispersive spectroscopic techniques were used to characterize the sample. The prepared material had average pore diameter of about 7-10 nm and the BET surface area of BiOCl was 40 m2 g-1. The analysis of hydroxyl radicals (•OH) formation was performed by fluorescence technique. The intermediates and the final products of degradation were detected by high-performance liquid chromatography-photodiode array-electrospray ionization-mass spectrometry (HPLC-ESI-DAD-MS) technology. The degradation of nile blue (NB) dye was mainly attributed to the destruction of the conjugated structure, and after that the intermediates were transformed into small molecules mainly phenol, aniline, etc., which were mineralized to water and carbon dioxide. During three recycles, the catalyst did not exhibit any significant loss of photocatalytic activity, confirming that the photocatalyst is essentially stable. The NB oxidation was evaluated by the decrease in total organic carbon (TOC) content. The formation of NO3- and the evolution of CO2 revealed complete mineralization of aqueous NB during the photocatalytic process by this photocatalyst.

  6. Water resources planning under climate change: Assessing the robustness of real options for the Blue Nile

    NASA Astrophysics Data System (ADS)

    Jeuland, Marc; Whittington, Dale

    2014-03-01

    This article presents a methodology for planning new water resources infrastructure investments and operating strategies in a world of climate change uncertainty. It combines a real options (e.g., options to defer, expand, contract, abandon, switch use, or otherwise alter a capital investment) approach with principles drawn from robust decision-making (RDM). RDM comprises a class of methods that are used to identify investment strategies that perform relatively well, compared to the alternatives, across a wide range of plausible future scenarios. Our proposed framework relies on a simulation model that includes linkages between climate change and system hydrology, combined with sensitivity analyses that explore how economic outcomes of investments in new dams vary with forecasts of changing runoff and other uncertainties. To demonstrate the framework, we consider the case of new multipurpose dams along the Blue Nile in Ethiopia. We model flexibility in design and operating decisions—the selection, sizing, and sequencing of new dams, and reservoir operating rules. Results show that there is no single investment plan that performs best across a range of plausible future runoff conditions. The decision-analytic framework is then used to identify dam configurations that are both robust to poor outcomes and sufficiently flexible to capture high upside benefits if favorable future climate and hydrological conditions should arise. The approach could be extended to explore design and operating features of development and adaptation projects other than dams.

  7. Evaluation of river discharges from ensemble global water resources reanalysis in the Upper Blue Nile basin

    NASA Astrophysics Data System (ADS)

    Belay, Haileyesus; Moges, Semu; Nikolopoulos, Efthymios; Anagnostou, Emmanouil

    2017-04-01

    The increased capacity of observational datasets, both from in-situ and remote sensors, along with the continuous advancements in earth system models and data assimilation algorithms, have led to the generation of a number of water resources reanalysis products that are available at global scale and high spatial and temporal resolution. These products hold a great potential for studies and applications related to water resources but their level of accuracy and range of uncertainty needs to be investigated and understood. In this work, we analyze and evaluate the runoff estimates from a multi-model global water resources reanalysis (WRR) dataset that was recently produced within the framework of Earth2Observe project (http: //www.earth2observe.eu). Evaluation of the WRR reanalysis is based on the comparison of streamflows derived from the ensemble WRR and available in situ observations for a range of basin scales in the Upper Blue Nile basin in Ethiopia. Analysis is carried out for different runoff properties (e.g. volume, maximum flows, duration curves) and for different temporal scales (daily, seasonal, annual) in order to evaluate the ability of WRR-based runoff estimates to represent various runoff characteristics. Results clearly indicate that the basin area and temporal scale are the most important controls on the performance of WRR streamflow simulations. Furthermore, results allow providing recommendations on application-specific use of WRR products and discussing potential bias correction techniques for improving river streamflow simulations.

  8. Nile blue shows its true colors in gas-phase absorption and luminescence ion spectroscopy

    NASA Astrophysics Data System (ADS)

    Stockett, M. H.; Houmøller, J.; Brøndsted Nielsen, S.

    2016-09-01

    Nile blue is used extensively in biology as a histological stain and fluorescent probe. Its absorption and emission spectra are strongly solvent dependent, with variations larger than 100 nm. The molecule is charged due to an iminium group, and it is therefore an obvious target for gas-phase ion spectroscopy. Here we report the absorption and emission spectra of the mass-selected bare ions isolated in vacuo, and based on our results we revisit the interpretation of solution-phase spectra. An accelerator mass spectrometer was used for absorption spectroscopy where the absorption is represented by the yield of photofragment ions versus excitation wavelength (action spectroscopy). The luminescence experiments were done with a newly built ion trap setup equipped with an electrospray ion source, and some details on the mass selection technique will be given which have not been described before. In vacuo, the absorption and emission maxima are at 580 ± 10 nm and 628 ± 1 nm. These values are somewhat blue-shifted relative to those obtained in most solvents; however, they are much further to the red than those in some of the most non-polar solvents. Furthermore, the Stokes shift in the gas phase (1300 cm-1) is much smaller than that in these non-polar solvents but similar to that in polar ones. An explanation based on charge localization by solvent dipoles, or by counterions in some non-polar solvents, can fully account for these findings. Hence in the case of ions, it is nontrivial to establish intrinsic electronic transition energies from solvatochromic shifts alone.

  9. N Isotopes in Nile Sediments (ethiopia, Sudan)

    NASA Astrophysics Data System (ADS)

    Padoan, M.; Villa, I. M.; Garzanti, E.; Galbusera, M.; Quistini, S.; Peruta, L.; El Kammar, A.

    2009-04-01

    The Nile is the most important river of the Eastern Mediterranean. Its water and sediment fluxes have greatly influenced marine circulation throughout the Quaternary, and are widely considered as possible causes for stagnation and formation of sapropel (Krom et al., 1999a; 2002; Talbot et al., 2000; Freydier et al., 2001; Weldeab et al., 2002; Scrivner et al., 2004). Variations in annual flooding and baseflow of the river Nile, controlled by climate changes, had major impact on the rise and demise of Egyptian dynasties (Stanley et al., 2003). In order to better define sedimentary sources of the Nile system and to obtain more robust results, we have analyzed Nd isotopes in sediments of all its major Sudanese and Ethiopian tributaries (Atbara, Gash, Abay, Didesa, Dabus, White Nile, Bahr Ez Zeraf) in several replicate samples. Analyses were carried out on distinct mud and sand fractions (<40 microns and 125-180 microns) of 30 samples, and systematic changes related to grain size and hydraulic-sorting processes could thus be investigated. On the same samples, companion studies are being carried out on Sr isotopes (Padoan et al., 2007) and on Pb isotopes at the Geological Survey of Israel (Harlavan et al., in preparation). Overall, isotopic signals are markedly different between the White Nile system, derived from largely Archean to Paleoproterozoic basement rocks, and Ethiopian tributaries, derived in diverse proportions from largely Neoproterozoic rift-shoulder basements and overlying Oligocene flood basalts. Isotopic signals of Main Nile sediments downstream of the Atbara confluence are close to those of Blue Nile sediments, indicating that detritus is mainly provided by the latter (Garzanti et al., 2006). In the White Nile branch, the 143Nd/144Nd ratio of the mud fraction is lower in the Bahr Ez Zeraf (0.51167) than in the White Nile downstrean of the Sobat confluence (0.51219), revealing significant sediment influx from the latter. In Blue Nile and Atbara branches

  10. Hydrological responses to land use/cover changes in the source region of the Upper Blue Nile Basin, Ethiopia.

    PubMed

    Woldesenbet, Tekalegn Ayele; Elagib, Nadir Ahmed; Ribbe, Lars; Heinrich, Jürgen

    2017-01-01

    Understanding how changes in distinctive land use/land cover (LULC) types influence the basin hydrology would greatly improve the predictability of the hydrological consequences of LULC dynamics for sustainable water resource management. As the main flow contributor to the River Nile, quantifying the effect of LULC change on water resources in the source regions is very important for the assessment of water resources availability and management downstream in the riparian states in general and the study watersheds in particular. In this study, an integrated approach comprising hydrological modeling and partial least squares regression (PLSR) was used to quantify the contributions of changes in individual LULC classes to changes in hydrological components. Two watersheds, namely Lake Tana and Beles in the Upper Blue Nile Basin in Ethiopia, were considered for the conduction of hydrological modeling using LULC maps and the Soil and Water Assessment Tool (SWAT). In the Tana sub-basin, it is found that expansion of cultivation land and decline in woody shrub are the major contributors to the rise in surface run-off and to the decline in the groundwater component. Similarly, decline of woodland and expansion of cultivation land are the major contributors to the increase in surface run-off and water yield in the Beles sub-basin. Increased run-off and reduced baseflow and actual evapotranspiration would have negative impacts on water resources, especially in relation to erosion and sedimentation in the upper Blue Nile River Basin. As a result, expansion of cultivation land and decline in woody shrub/woodland appear to be major environmental stressors affecting local water resources. The wider implications of the hydrological changes on the Easter Nile water resources are briefly discussed. The approach to assessing changes in basin hydrology could generally be applied to a variety of other watersheds for which temporal digital LULC maps are available.

  11. Sediment concentration rating curves for a monsoonal climate: upper Blue Nile

    NASA Astrophysics Data System (ADS)

    Moges, Mamaru A.; Zemale, Fasikaw A.; Alemu, Muluken L.; Ayele, Getaneh K.; Dagnew, Dessalegn C.; Tilahun, Seifu A.; Steenhuis, Tammo S.

    2016-07-01

    Information on sediment concentration in rivers is important for design of reservoirs and for environmental applications. Because of the scarcity of continuous sediment data, methods have been developed to predict sediment loads based on few discontinuous measurements. Traditionally, loads are being predicted using rating curves that relate sediment load to discharge. The relationship assumes inherently a unique relationship between concentration and discharge and therefore although performing satisfactorily in predicting loads, it may be less suitable for predicting concentration. This is especially true in the Blue Nile Basin of Ethiopia where concentrations decrease for a given discharge with the progression of the rainy monsoon phase. The objective of this paper is to improve the sediment concentration predictions throughout the monsoon period for the Ethiopian highlands with a modified rating type equation. To capture the observed sediment concentration pattern, we assume that the sediment concentration was at the transport limit early in the rainy season and then decreases linearly with effective rainfall towards source-limited concentration. The modified concentration rating curve was calibrated for the four main rivers in the Lake Tana basin where sediment concentrations affect fish production and tourism. Then the scalability of the rating type equation was checked in three 100 ha watersheds for which historic data were available. The results show that for predicting sediment concentrations, the (modified) concentration rating curve was more accurate than the (standard) load rating curve as expected. In addition loads were predicted more accurately for three of the four rivers. We expect that after more extensive testing over a wider geographical area, the proposed concentration rating curve will offer improved predictions of sediment concentrations in monsoonal climates.

  12. Sediment concentration rating curves for a monsoonal climate: upper Blue Nile Basin

    NASA Astrophysics Data System (ADS)

    Moges, M. A.; Zemale, F. A.; Alemu, M. L.; Ayele, G. K.; Dagnew, D. C.; Tilahun, S. A.; Steenhuis, T. S.

    2015-12-01

    Information on sediment content in rivers is important for design of reservoirs and for environmental applications. Because of scarcity of continuous sediment data, methods have been developed to predict sediment loads based on few discontinuous measurements. Traditionally, loads are being predicted using rating curves that relate sediment load to discharge. The relationship assumes inherently a unique relationship between concentration and discharge and therefore although performing satisfactorily in predicting loads, it may be less suitable for predicting concentration. This is especially true in the Blue Nile basin of Ethiopia where concentrations decrease for a given discharge with the progression of the rainy monsoon phase. The objective of this paper is to improve the sediment concentration predictions throughout the monsoon period for the Ethiopian highlands with a modified rating type equation. To capture the observed sediment concentration pattern, we assume that the sediment concentration was at the transport limit early in the rainy season and then decrease linearly with effective rainfall towards source limited concentration. The modified concentration rating curve was calibrated for the four main rivers in the Lake Tana basin where sediment concentrations affect fish production and tourism. Then the scalability of the rating type equation was checked in three 100-ha watersheds for which historic data was available. The results show, that for predicting sediment concentrations, the (modified) concentration rating curve was more accurate than the (standard) load rating curve as expected. In addition loads were predicted more accurately for three of the four rivers. We expect that after more extensive testing over a wider geographical area, the proposed concentration rating curve will offer improved predictions of sediment concentrations in monsoonal climates.

  13. Hydrochemical evaluation of groundwater in the Blue Nile Basin, eastern Sudan, using conventional and multivariate techniques

    NASA Astrophysics Data System (ADS)

    Hussein, Mohammed Tahir

    Hydrochemical evaluation of groundwater systems can be carried out using conventional and multivariate techniques, namely cluster, factor analyses and others such as correspondence analysis. The main objective of this study is to investigate the groundwater quality in the Blue Nile basin of eastern Sudan, and to workout a hydrochemical evaluation for the aquifer system. Conventional methods and multivariate techniques were applied to achieve these goals. Two water-bearing layers exist in the study area: the Nubian Sandstone Formation and the Al-Atshan Formation. The Nubian aquifer is recharged mainly from the Blue Nile and Dinder Rivers through lateral subsurface flow and through direct rainfall in outcrop areas. The Al-Atshan aquifer receives water through underground flow from River Rahad and from rainfall infiltration. The prevailing hydrochemical processes are simple dissolution, mixing, partial ion exchange and ion exchange. Limited reverse ion exchange has been witnessed in the Nubian aquifer. Three factors control the overall mineralization and water quality of the Blue Nile Basin. The first factor includes high values of total dissolved solids, electrical conductivity, sodium, potassium, chloride, bicarbonate, sulphate and magnesium. The second factor includes calcium and pH. The third factor is due to fluoride concentration in the groundwater. The study highlights the descriptive capabilities of conventional and multivariate techniques as effective tools in groundwater quality evaluation. Une étude hydrochimique de systèmes aquifères a pu être réalisée au moyen des techniques conventionnelles et multidimensionnelles, telles que les analyses de cluster et factorielles, ainsi que d'autres comme l'analyse des correspondances. Le principal objectif de ce travail est d'étudier la qualité des eaux souterraines du bassin du Nil bleu au Soudan oriental, et de réaliser une évaluation hydrochimique du système aquifère. Des méthodes conventionnelles et

  14. Screening reservoir systems by considering the efficient trade-offs—informing infrastructure investment decisions on the Blue Nile

    NASA Astrophysics Data System (ADS)

    Geressu, Robel T.; Harou, Julien J.

    2015-12-01

    Multi-reservoir system planners should consider how new dams impact downstream reservoirs and the potential contribution of each component to coordinated management. We propose an optimized multi-criteria screening approach to identify best performing designs, i.e., the selection, size and operating rules of new reservoirs within multi-reservoir systems. Reservoir release operating rules and storage sizes are optimized concurrently for each separate infrastructure design under consideration. Outputs reveal system trade-offs using multi-dimensional scatter plots where each point represents an approximately Pareto-optimal design. The method is applied to proposed Blue Nile River reservoirs in Ethiopia, where trade-offs between total and firm energy output, aggregate storage and downstream irrigation and energy provision for the best performing designs are evaluated. This proof-of concept study shows that recommended Blue Nile system designs would depend on whether monthly firm energy or annual energy is prioritized. 39 TWh/yr of energy potential is available from the proposed Blue Nile reservoirs. The results show that depending on the amount of energy deemed sufficient, the current maximum capacities of the planned reservoirs could be larger than they need to be. The method can also be used to inform which of the proposed reservoir type and their storage sizes would allow for the highest downstream benefits to Sudan in different objectives of upstream operating objectives (i.e., operated to maximize either average annual energy or firm energy). The proposed approach identifies the most promising system designs, reveals how they imply different trade-offs between metrics of system performance, and helps system planners asses the sensitivity of overall performance to the design parameters of component reservoirs.

  15. Hydrologic interconnection between the volcanic aquifer and springs, Lake Tana basin on the Upper Blue Nile

    NASA Astrophysics Data System (ADS)

    Nigate, Fenta; Van Camp, Marc; Kebede, Seifu; Walraevens, Kristine

    2016-09-01

    Hydrochemical and stable isotope (δ18O, δ2H) data were used to identify the recharge sources of major springs and the hydraulic interconnection between the volcanic aquifer and springs in the Gilgel Abay catchment and adjacent areas. The hydrochemical data analysis showed that all water samples of springs and shallow wells have freshwater chemistry, Casbnd HCO3 to Casbnd Mgsbnd HCO3 types. This is mainly controlled by dissolution/hydrolysis of silicate minerals. The analyzed stable isotope data indicate that springs water, except Dengel Mesk, Kurt Bahir and Bility springs, and well waters, except Dangila well, fall close to the LMWL. This clearly shows that the infiltrated rainwater did not undergo much evaporation and δ18O values for spring water and groundwater are nearly equal to the value of Ethiopian summer rainfall, which is -2.5‰. Therefore, generally both stable isotope and hydrochemical data show the recharge source to springs and shallow groundwater is primarily from precipitation. Furthermore, data suggest that rock-water interaction has remained relatively limited, pointing to relatively short residence times, and local recharge rather than regional recharge.

  16. Nile Blue-based nanosized pH sensors for simultaneous far-red and near-infrared live bioimaging.

    PubMed

    Madsen, Jeppe; Canton, Irene; Warren, Nicholas J; Themistou, Efrosyni; Blanazs, Adam; Ustbas, Burcin; Tian, Xiaohe; Pearson, Russell; Battaglia, Giuseppe; Lewis, Andrew L; Armes, Steven P

    2013-10-02

    Diblock copolymer vesicles are tagged with pH-responsive Nile Blue-based labels and used as a new type of pH-responsive colorimetric/fluorescent biosensor for far-red and near-infrared imaging of live cells. The diblock copolymer vesicles described herein are based on poly(2-(methacryloyloxy)ethyl phosphorylcholine-block-2-(diisopropylamino)ethyl methacrylate) [PMPC-PDPA]: the biomimetic PMPC block is known to facilitate rapid cell uptake for a wide range of cell lines, while the PDPA block constitutes the pH-responsive component that enables facile vesicle self-assembly in aqueous solution. These biocompatible vesicles can be utilized to detect interstitial hypoxic/acidic regions in a tumor model via a pH-dependent colorimetric shift. In addition, they are also useful for selective intracellular staining of lysosomes and early endosomes via subtle changes in fluorescence emission. Such nanoparticles combine efficient cellular uptake with a pH-responsive Nile Blue dye label to produce a highly versatile dual capability probe. This is in marked contrast to small molecule dyes, which are usually poorly uptaken by cells, frequently exhibit cytotoxicity, and are characterized by intracellular distributions invariably dictated by their hydrophilic/hydrophobic balance.

  17. Nile Blue-Based Nanosized pH Sensors for Simultaneous Far-Red and Near-Infrared Live Bioimaging

    PubMed Central

    2013-01-01

    Diblock copolymer vesicles are tagged with pH-responsive Nile Blue-based labels and used as a new type of pH-responsive colorimetric/fluorescent biosensor for far-red and near-infrared imaging of live cells. The diblock copolymer vesicles described herein are based on poly(2-(methacryloyloxy)ethyl phosphorylcholine-block-2-(diisopropylamino)ethyl methacrylate) [PMPC-PDPA]: the biomimetic PMPC block is known to facilitate rapid cell uptake for a wide range of cell lines, while the PDPA block constitutes the pH-responsive component that enables facile vesicle self-assembly in aqueous solution. These biocompatible vesicles can be utilized to detect interstitial hypoxic/acidic regions in a tumor model via a pH-dependent colorimetric shift. In addition, they are also useful for selective intracellular staining of lysosomes and early endosomes via subtle changes in fluorescence emission. Such nanoparticles combine efficient cellular uptake with a pH-responsive Nile Blue dye label to produce a highly versatile dual capability probe. This is in marked contrast to small molecule dyes, which are usually poorly uptaken by cells, frequently exhibit cytotoxicity, and are characterized by intracellular distributions invariably dictated by their hydrophilic/hydrophobic balance. PMID:24001153

  18. Assessment of Active Landslides in Sanbaro Sago Valley, Blue-Nile Catchment, Ethiopia

    NASA Astrophysics Data System (ADS)

    Hailemariam Gugsa, Trufat

    2010-05-01

    In fall of 2009, a detail field mapping was carried out in the Sanbaro Sago Valley, south-eastern of Blue-Nile catchment, to inspect the landslide processes that affected the livelihood of more than 6,000 peoples. The valley is a part of Ethiopian highlands where long histories of rainfall triggered landslides are prominent. The villagers suffered the recurring landslides for the last five years, even at present; there are numerous evidences of active landslides, with some actual slides currently taking place. The nature their activity indicate high probability of destructive phenomena within the foreseeable future. The landslides already damaged houses, farm plots and drainage ditch, as well; more than 40 causalities are recorded. Most of the dwellers have been permanently displaced from their residences, as they lost their houses and farm plots. A preliminary zoning was made through the interpretation of satellite images (+ETM Land sat) that drape over the digital elevation model of the area, which followed by detail field investigation to map the geological, geomorphological, and anthropogenic factors that contribute to the landslide activity. The valley consists of low lying graben bounded by steep scarps that characterized by highly weathered Tertiary basaltic rocks covered with Quaternary deposits. Structurally controlled, alluvial and denudational landforms are present. There are distinct geomorphic units formed by differences in the lithology of the various basalt types. The Quaternary deposits along the ridge that has many rills and incised gullies are characterized by weathered basalts and alluvial-colluvial deposits. The elevation of the valley ranges from 1290m to 3200m m.a.s.l. The steep slopes, volcanic hills, exposed on the downthrown side of the major scarps have been modified by erosion, resulting in a highly dissected topography with steep gullies. This makes the steep slopes of the ridge to be one of landslide prone areas. Many of the active

  19. Predictability of current and future multi-river discharges: Ganges, Brahmaputra, Yangtze, Blue Nile, and Murray-Darling rivers

    NASA Astrophysics Data System (ADS)

    Jian, Jun

    2007-12-01

    Determining river discharge is of critical importance to many societies as they struggle with fresh water supply and risk of flooding. In Bangladesh, floods occur almost every year but with sufficient irregularity to have adverse social and economical consequences. Important goals are to predict the discharge to be used for the optimization of agricultural practices, disaster mitigation and water resource management. The aim of this study is to determine the predictability of river discharge in a number of major rivers on time scale varying from weeks to a century. We investigated predictability considering relationship between SST and discharge. Next, we consider IPCC model projections of river discharge while the models are statistically adjusted against observed discharges. In this study, we consider five rivers, the Ganges, the Brahmaputra, the Yangtze, the Blue Nile, and the Murray-Darling Rivers. On seasonal time scales, statistically significant correlations are found between mean monthly equatorial Pacific sea surface temperature (SST) and the summer Ganges discharge with lead times of 2-3 months due to oscillations of the El Nino-Southern Oscillation (ENSO) phenomena. In addition, there are strong correlations in the southwest and northeast Pacific. These, too, appear to be tied to the ENSO cycle. The Brahmaputra discharge, on the other hand, shows somewhat weaker relationships with tropical SST. Strong lagged correlations relationships are found with SST in the Bay of Bengal but these are the result of very warm SSTs and exceptional Brahmaputra discharge during the summer of 1998. When this year is removed from the time series, relationships weaken everywhere except in the northwestern Pacific for the June discharge and in areas of the central Pacific straddling the equator for the July discharge. The relationships are relative strong, but they are persistent from month to month and suggest that two different and sequential factors influence Brahmaputra

  20. Methods for interfacing IPCC climate change scenarios with higher resolution watershed management models in the Ethiopian Blue Nile Basin

    NASA Astrophysics Data System (ADS)

    Easton, Z. M.; MacAlister, C.; Fuka, D. R.

    2013-12-01

    As much as 90% of the Nile River flow that reaches Egypt originates in the Highlands of the Ethiopian Blue Nile Basin. This imbalance in water availability poses a threat to water security in the region, and could be severely impacted by projected climate change. This analysis coupled hydrodynamic/watershed models with the Intergovernmental Panel on Climate Change (IPCC) AR4 climate change scenarios to assess the potential impact on water resources and sediment dynamics. Specific AR4 scenarios include the A1B, B1, B2 and COMMIT, which were used to force the baseline hydrodynamic models calibrated against 1979-2011 streamflow for 20 sub-watersheds in the Tana and Beles basins. Transfer functions were developed to distribute the model parameters from the calibrated sub-watersheds to un-gauged portions of the basins based on a similarity index of hydrologic response units. We analyzed the scenario in two manners: first we ran all of the seven individual Global Circulation Model results in the IPCC AR4 report though our watershed models to asses the potential spread of climate change predictions; then we assessed the mean value produced for each IPCC AR4 scenario to better estimate convergence. Results indicate that the Tana basin is expected to experience an increase in mean annual flow. The Beles basin is predicted to experience a small decrease in mean annual flow. Sediment concentrations in the Tana basin increase proportionally more than the flow increase. Interestingly, and perhaps counter to what might be expected for a decrease in flow in the Beles basin, sediment concentrations increase.

  1. Trend analysis of runoff and sediment fluxes in the Upper Blue Nile basin: A combined analysis of statistical tests, physically-based models and landuse maps

    NASA Astrophysics Data System (ADS)

    Gebremicael, T. G.; Mohamed, Y. A.; Betrie, G. D.; van der Zaag, P.; Teferi, E.

    2013-03-01

    SummaryThe landuse/cover changes in the Ethiopian highlands have significantly increased the variability of runoff and sediment fluxes of the Blue Nile River during the last few decades. The objectives of this study were (i) to understand the long-term variations of runoff and sediment fluxes using statistical models, (ii) to interpret and corroborate the statistical results using a physically-based hydrological model, Soil and Water Assessment Tool (SWAT), and (iii) to validate the interpretation of SWAT results by assessing changes of landuse maps. Firstly, Mann-Kendall and Pettitt tests were used to test the trends of Blue Nile flow (1970-2009) and sediment load (1980-2009) at the outlet of the Upper Blue Nile basin at El Diem station. These tests showed statistically significant increasing trends of annual stream flow, wet season stream flow and sediment load at 5% confidence level. The dry season flow showed a significant decrease in the trend. However, during the same period the annual rainfall over the basin showed no significant trends. The results of the statistical tests were sensitive to the time domain. Secondly, the SWAT model was used to simulate the runoff and sediment fluxes in the early 1970s and at the end of the time series in 2000s in order to interpret the physical causes of the trends and corroborate the statistical results. A comparison of model parameter values between the 1970s and 2000s shows significant change, which could explain catchment response changes over the 28 years of record. Thirdly, a comparison of landuse maps of 1970s against 2000s shows conversion of vegetation cover into agriculture and grass lands over wide areas of the Upper Blue Nile basin. The combined results of the statistical tests, the SWAT model, and landuse change detection are consistent with the hypothesis that landuse change has caused a significant change of runoff and sediment load from the Upper Blue Nile during the last four decades. This is an important

  2. Comprehensive assessment of soil erosion risk for better land use planning in river basins: Case study of the Upper Blue Nile River.

    PubMed

    Haregeweyn, Nigussie; Tsunekawa, Atsushi; Poesen, Jean; Tsubo, Mitsuru; Meshesha, Derege Tsegaye; Fenta, Ayele Almaw; Nyssen, Jan; Adgo, Enyew

    2017-01-01

    In the drought-prone Upper Blue Nile River (UBNR) basin of Ethiopia, soil erosion by water results in significant consequences that also affect downstream countries. However, there have been limited comprehensive studies of this and other basins with diverse agroecologies. We analyzed the variability of gross soil loss and sediment yield rates under present and expected future conditions using a newly devised methodological framework. The results showed that the basin generates an average soil loss rate of 27.5tha(-1)yr(-1) and a gross soil loss of ca. 473Mtyr(-1), of which, at least 10% comes from gully erosion and 26.7% leaves Ethiopia. In a factor analysis, variation in agroecology (average factor score=1.32) and slope (1.28) were the two factors most responsible for this high spatial variability. About 39% of the basin area is experiencing severe to very severe (>30tha(-1)yr(-1)) soil erosion risk, which is strongly linked to population density. Severe or very severe soil erosion affects the largest proportion of land in three subbasins of the UBNR basin: Blue Nile 4 (53.9%), Blue Nile 3 (45.1%), and Jema Shet (42.5%). If appropriate soil and water conservation practices targeted ca. 77.3% of the area with moderate to severe erosion (>15tha(-1)yr(-1)), the total soil loss from the basin could be reduced by ca. 52%. Our methodological framework identified the potential risk for soil erosion in large-scale zones, and with a more sophisticated model and input data of higher spatial and temporal resolution, results could be specified locally within these risk zones. Accurate assessment of soil erosion in the UBNR basin would support sustainable use of the basin's land resources and possibly open up prospects for cooperation in the Eastern Nile region. Copyright © 2016 Office national des forêts. Published by Elsevier B.V. All rights reserved.

  3. Value versus Accuracy: application of seasonal forecasts to a hydro-economic optimization model for the Sudanese Blue Nile

    NASA Astrophysics Data System (ADS)

    Satti, S.; Zaitchik, B. F.; Siddiqui, S.; Badr, H. S.; Shukla, S.; Peters-Lidard, C. D.

    2015-12-01

    The unpredictable nature of precipitation within the East African (EA) region makes it one of the most vulnerable, food insecure regions in the world. There is a vital need for forecasts to inform decision makers, both local and regional, and to help formulate the region's climate change adaptation strategies. Here, we present a suite of different seasonal forecast models, both statistical and dynamical, for the EA region. Objective regionalization is performed for EA on the basis of interannual variability in precipitation in both observations and models. This regionalization is applied as the basis for calculating a number of standard skill scores to evaluate each model's forecast accuracy. A dynamically linked Land Surface Model (LSM) is then applied to determine forecasted flows, which drive the Sudanese Hydroeconomic Optimization Model (SHOM). SHOM combines hydrologic, agronomic and economic inputs to determine the optimal decisions that maximize economic benefits along the Sudanese Blue Nile. This modeling sequence is designed to derive the potential added value of information of each forecasting model to agriculture and hydropower management. A rank of each model's forecasting skill score along with its added value of information is analyzed in order compare the performance of each forecast. This research aims to improve understanding of how characteristics of accuracy, lead time, and uncertainty of seasonal forecasts influence their utility to water resources decision makers who utilize them.

  4. Comparative evaluation of different satellite rainfall estimation products and bias correction in the Upper Blue Nile (UBN) basin

    NASA Astrophysics Data System (ADS)

    Abera, Wuletawu; Brocca, Luca; Rigon, Riccardo

    2016-09-01

    In a region where ground-based gauge data are scarce, satellite rainfall estimates (SREs) are a viable option for proper space-time rainfall characterization. However, their accuracy and performances vary from region to region, and must be assessed. In this study, five high resolution satellite products (3B42V7, CMORPH, TAMSAT, SM2R-CCI, and CFSR) are compared and analyzed using the available rain gauge data in one of the most topographically and climatologically complex basin of Africa, the Upper Blue Nile basin (UBN). The basin rainfall is investigated systematically, and it is found that, at some locations, the difference in mean annual rainfall estimates between these SREs could be as much as about 2700 mm. Considering three goodness-of-fit indexes, correlation, bias and root mean square error (RMSE) between the SREs and ground-based gauge rainfall, CMORPH, TAMSAT and SM2R-CCI outperform the other two. Furthermore, a confusion matrix is used to investigate the detection ability of satellite rainfall products for different rainfall intensities. TAMSAT has the highest (91%) detection skill for dry days, followed by CFSR (77%). On the contrary, SM2R-CCI has the highest accuracy index for medium rainfall ranges (10-20 mm). The empirical cumulative distribution (ecdf) mapping technique is used to correct the intensities distribution givenby the SREs. This method provides a means to improve the rainfall estimation of all SREs, and the highest improvement is obtained for CMORPH (bias reduction from - 72% to - 1%).

  5. Complete mitochondrial DNA sequences of the Nile tilapia (Oreochromis niloticus) and Blue tilapia (Oreochromis aureus): genome characterization and phylogeny applications.

    PubMed

    He, Anyuan; Luo, Yongju; Yang, Hong; Liu, Liping; Li, Sifa; Wang, Chenghui

    2011-03-01

    Cichlid fishes have played an important role in evolutionary biology and aquaculture industry. Nile tilapia (Oreochromis niloticus), blue tilapia (Oreochromis aureus) and Mozambique tilapia (Oreochromis mossambicus), the useful models in studying evolutionary biology within Cichlid fishes, are also mainly cultured species in aquaculture with great economic importance. In this paper, the complete nucleotide sequence of the mitochondrial genome for O. niloticus and O. aureus were determined and phylogenetic analyses from mitochondrial protein-coding genes were conducted to explore their phylogenetic relationship within Cichlids. The mitogenome is 16,625 bp for O. niloticus and 16,628 bp for O. aureus, containing the same gene order and an identical number of genes or regions with the other Cichlid fishes, including 13 protein-coding genes, two rRNA genes, 22 tRNA genes and one putative control region. Phylogenetic analyses using three different computational algorithms (maximum parsimony, maximum likelihood and Bayesian method) show O. niloticus and O. mossambicus are closely related, and O. aureus has remotely phylogenetic relationship from above two fishes.

  6. Label-free electrochemical immunosensor based on Nile blue A-reduced graphene oxide nanocomposites for carcinoembryonic antigen detection.

    PubMed

    Gao, Yan-Sha; Zhu, Xiao-Fei; Xu, Jing-Kun; Lu, Li-Min; Wang, Wen-Min; Yang, Tao-Tao; Xing, Hua-Kun; Yu, Yong-Fang

    2016-05-01

    In this article, a novel, label-free, and inherent electroactive redox immunosensor for carcinoembryonic antigen (CEA) based on gold nanoparticles (AuNPs) and Nile blue A (NB) hybridized electrochemically reduced graphene oxide (NB-ERGO) is proposed. The composite of NB-graphene oxide (NB-GO) was prepared by π-π stacking interaction. Then, chronoamperometry was adopted to simultaneously reduce HAuCl4 and nanocomposites of NB-GO for synthesizing AuNPs/NB-ERGO. The immunosensor was fabricated by capturing CEA antibody (anti-CEA) at this nanocomposite modified electrode. The immunosensor determination was based on the fact that, due to the formation of antigen-antibody immunocomplex, the decreased response currents of NB were directly proportional to the concentrations of CEA. Under optimal conditions, the linear range of the proposed immunosensor was estimated to be from 0.001 to 40 ng ml(-1) and the detection limit was estimated to be 0.00045 ng ml(-1). The proposed immunosensor was used to determine CEA in clinical serum samples with satisfactory results. The proposed method may provide promising potential application in clinical immunoassays with the properties of facile procedure, stability, high sensitivity, and selectivity.

  7. Thermal cycling and the optical and electrical characterization of self-assembled multilayer Nile Blue A-gold thin films

    SciTech Connect

    Geist, Brian; Spillman, William B.; Claus, Richard O

    2005-10-20

    Some laser applications produce high power densities that can be dangerous to equipment and operators. We have fabricated thin-film coatings by using molecular electrostatic self-assembly to create a spectrally selective absorbing coating that is able to withstand thermal fluctuations from -20 deg. C to 120 deg. C. We made the thin-film coatings by alternating deposition of an organic dye and gold colloidal nanoparticles onto glass substrates. Nile Blue A perchlorate, with a maximum absorbance slightly above 632 nm, was chosen as the organic dye. Strong coupling between the dye molecules and the gold nanoparticles provides a redshift that increases as the film's thickness is increased. The incorporation of the gold colloidal nanoparticles also decreases the resistivity of the film. The resistivity of the film was measured with a four-point probe and found to be {approx}10 {omega}/cm for the two samples measured. Atomic-force microscopy was used to show that film thickness increased 2.4nm per bilayer. The optical properties of the film were measured at the end of every 5 thermal cycles from -20 deg. C to 120 deg. C, and negligible degradation was observed after 30 cycles.

  8. Thermal cycling and the optical and electrical characterization of self-assembled multilayer nile blue A-gold thin films.

    PubMed

    Geist, Brian; Spillman, William B; Claus, Richard O

    2005-10-20

    Some laser applications produce high power densities that can be dangerous to equipment and operators. We have fabricated thin-film coatings by using molecular electrostatic self-assembly to create a spectrally selective absorbing coating that is able to withstand thermal fluctuations from -20 degrees C to 120 degrees C. We made the thin-film coatings by alternating deposition of an organic dye and gold colloidal nanoparticles onto glass substrates. Nile Blue A perchlorate, with a maximum absorbance slightly above 632 nm, was chosen as the organic dye. Strong coupling between the dye molecules and the gold nanoparticles provides a redshift that increases as the film's thickness is increased. The incorporation of the gold colloidal nanoparticles also decreases the resistivity of the film. The resistivity of the film was measured with a four-point probe and found to be approximately 10 omega/cm for the two samples measured. Atomic-force microscopy was used to show that film thickness increased 2.4 nm per bilayer. The optical properties of the film were measured at the end of every 5 thermal cycles from -20 degrees C to 120 degrees C, and negligible degradation was observed after 30 cycles.

  9. Thermal cycling and the optical and electrical characterization of self-assembled multilayer Nile Blue A gold thin films

    NASA Astrophysics Data System (ADS)

    Geist, Brian; Spillman, William B.; Claus, Richard O.

    2005-10-01

    Some laser applications produce high power densities that can be dangerous to equipment and operators. We have fabricated thin-film coatings by using molecular electrostatic self-assembly to create a spectrally selective absorbing coating that is able to withstand thermal fluctuations from -20 °C to 120 °C. We made the thin-film coatings by alternating deposition of an organic dye and gold colloidal nanoparticles onto glass substrates. Nile Blue A perchlorate, with a maximum absorbance slightly above 632 nm, was chosen as the organic dye. Strong coupling between the dye molecules and the gold nanoparticles provides a redshift that increases as the film's thickness is increased. The incorporation of the gold colloidal nanoparticles also decreases the resistivity of the film. The resistivity of the film was measured with a four-point probe and found to be ˜10 Ω/cm for the two samples measured. Atomic-force microscopy was used to show that film thickness increased 2.4nm per bilayer. The optical properties of the film were measured at the end of every 5 thermal cycles from -20 °C to 120 °C, and negligible degradation was observed after 30 cycles.

  10. Water Dynamics in Fogera and the Upper Blue Nile - Farmers perspectives and remote sensing

    NASA Astrophysics Data System (ADS)

    Chemin, Yann; Desalegn, Mengistu; Curnow, Jayne; Johnston, Robyn

    2015-04-01

    This research work is about finding the connection between farmers perspectives on changes of water conditions in their socio-agricultural environment and satellite remote sensing analysis. Key informant surveys were conducted to investigate localised views on water scarcity as a counterpoint to the physical measurement of water availability. Does a numerical or mapped image identifying water scarcity always equate to a dearth of water for agriculture? To push the limits of the relationship between human and physical data we sought to ground-truth GIS results with the practical experience and knowledge of people living in the area. We data-mined public domain satellite data with FOSS (GDAL, GRASS GIS) and produced water-related spatio-temporal domains for our study area and the larger Upper Nile Basin. Accumulated remote sensing information was then cross-referenced with informant's accounts of water availability for the same space and time. During the survey fieldwork the team also took photographs electronically stamped with GPS coordinates to compare and contrast the views of informants and the remote sensing information with high resolution images of the landscape. We found that farmers perspective on the Spring maize crop sensibility to variability of rainfall can be quantified in space and time by remote sensing cumulative transpiration. A crop transpiration gap of 1-2.5 mm/day for about 20 days is to be overcome, a full amount of 20 to 50 mm, depending on the type of year deficit. Such gap can be overcome, even by temporary supplemental irrigation practices, however, the economical and cultural set up is already developed in another way, as per sesonal renting of higher soil profile water retention capacity fields.

  11. Evaluation of high resolution global satellite precipitation products using daily raingauge data over the Upper Blue Nile Basin

    NASA Astrophysics Data System (ADS)

    Sahlu, Dejene; Moges, Semu; Anagnostou, Emmanouil; Nikolopoulos, Efthymios; Hailu, Dereje; Mei, Yiwen

    2017-04-01

    Water resources assessment, planning and management in Africa is often constrained by the lack of reliable spatio-temporal rainfall data. Satellite products are steadily growing and offering useful alternative datasets of rainfall globally. The aim of this paper is to examine the error characteristics of the main available global satellite precipitation products with the view of improving the reliability of wet season (June to September) and small rainy season rainfall datasets over the Upper Blue Nile Basin. The study utilized six satellite derived precipitation datasets at 0.25-deg spatial grid size and daily temporal resolution:1) the near real-time (3B42_RT) and gauge adjusted (3B42_V7) products of Tropical Rainfall Measuring Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA), 2) gauge adjusted and unadjusted Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks (PERSIANN) products and 3) the gauge adjusted and un-adjusted product of the National Oceanic and Atmospheric Administration (NOAA) Climate Prediction Center Morphing technique (CMORPH) over the period of 2000 to 2013.The error analysis utilized statistical techniques using bias ratio (Bias), correlation coefficient (CC) and root-mean-square-error (RMSE). Mean relative error (MRE), CC and RMSE metrics are further examined for six categories of 10th, 25th, 50th, 75th, 90thand 95th percentile rainfall thresholds. The skill of the satellite estimates is evaluated using categorical error metrics of missed rainfall volume fraction (MRV), falsely detected rainfall volume fraction (FRV), probability of detection (POD) and False Alarm Ratio (FAR). Results showed that six satellite based rainfall products underestimated wet season (June to September) gauge precipitation, with the exception of non-adjusted PERSIANN that overestimated the initial part of the rainy season (March to May). During the wet season, adjusted CMORPH has relatively better bias ratio (89

  12. A dual-wavelength overlapping resonance Rayleigh scattering method for the determination of chondroitin sulfate with nile blue sulfate

    NASA Astrophysics Data System (ADS)

    Cui, Zhiping; Hu, Xiaoli; Liu, Shaopu; Liu, Zhongfang

    2011-12-01

    A dual-wavelength overlapping resonance Rayleigh scattering (DWO-RRS) method was developed to detect chondroitin sulfate (CS) with nile blue sulfate (NBS). At pH 3.0-4.0 Britton-Robinson (BR) buffer medium, CS interacted with NBS to form an ion-association complex. As a result, the new spectra of resonance Rayleigh scattering (RRS), second order scattering (SOS) and frequence doubling scattering (FDS) appeared and their intensities were enhanced greatly. Their maximum wavelengths were located at 303 nm (RRS), 362 nm (RRS), 588 nm (SOS) and 350 nm (FDS), respectively. The scattering intensities of the three methods were proportional to the concentration of CS in certain ranges. The methods had high sensitivity and the detection limits were between 1.5 and 7.1 ng mL -1. The DWO-RRS method had the highest sensitivity with the detection limit being 1.5 ng mL -1. The characteristics of the spectra and optimal reaction conditions of RRS method were investigated. The effects of coexistent substances on the determination of CS were evaluated. Owing to the high sensitivity, RRS method had been applied to the determination of CS in eye drops with satisfactory results. The recovery range was between 99.4% and 104.6% and the relative standard deviation (RSD) was between 0.4% and 0.8%. In addition, the reasons for RRS enhancement were discussed and the shape of ion-association complex was characterized by atomic force microscopy (AFM).

  13. Linking soil erosion to on-site financial cost: lessons from watersheds in the Blue Nile basin

    NASA Astrophysics Data System (ADS)

    Erkossa, T.; Wudneh, A.; Desalegn, B.; Taye, G.

    2015-06-01

    The study was conducted in three watersheds (Dapo, Meja and Mizewa) in the Ethiopian part of the Blue Nile Basin to estimate the on-site cost of soil erosion using the productivity change approach, in which crop yield reduction due to plant nutrients lost with the sediment and runoff has been analysed. For this purpose, runoff measurement and sampling was conducted during the main rainy season of 2011 at the outlet of two to three sub-watersheds in each watershed. The sediment concentration of the runoff, and N and P contents in runoff and sediment were determined. Crop response functions were developed for the two plant nutrients based on data obtained from the nearest Agricultural Research Centres. The response functions were used to estimate crop yield reduction as a result of the lost N and P assuming there is no compensation through fertilization. The results show a significant yield reduction and resultant financial loss to the farmers. Considering only grain yield of maize (Zea mays), farmers at Dapo annually lose about USD 220 ha-1 and 150 ha-1 due to the loss of N and P, respectively. In view of the importance of the crop residues, including as feed, the loss can be even greater. The study demonstrated that in addition to the long-term deterioration of land quality, the annual financial loss suffered by farmers is substantial. Therefore, on farm soil and water conservation measures that are suitable in biophysical and socio-economic terms in the landscapes and beyond need to be encouraged.

  14. Assessing Impact of Climate Change on the Runoffs of Gilgel Abbay Watershed, the upper Blue Nile Basin, Ethiopia

    NASA Astrophysics Data System (ADS)

    Ayele, H. S.; Li, M. H.; Tung, C. P.; Liu, T. M.

    2015-12-01

    Water is the most climate sensitive sector in changing climate. Hydrological vulnerability assessment is critical to the implementation of adaption measures. In this study, projections of 7 GCMs in association with high (RCP8.5) and medium low (RCP4.5) representative concentration path way from the CMPI5 (fifth phase of the Coupled Model Intercomparison Project) for the period 2021-2040 and 2081-2100 were adopted to assess the impacts of climate change on the runoffs of Gilgel Abbay watershed, the upper Blue Nile basin, in Ethiopia. The GCMs selected were first screened in harmony with baseline climate statistics of study areas. Based on climate projections and statistical characteristics of historical weather data, a weather generator was employed to generate daily temperature and precipitation as inputs for the GWLF hydrological model to simulate runoffs. Changes of projected temperature and precipitation were analyzed to explain variations of evapotranspiration and influences on future runoffs. We found that, despite the fact that the projected magnitude varies among different GCMs, increasing in the wet and a decreasing in dry seasons runoffs were observed in both time windows, which mainly attributes to the increase of precipitations projected by most of GCMs. In contrast to great increases in runoffs, the increase of evapotranspiration by elevating temperature is less significant. The increasing runoffs in both time windows will provide more water inflow to the Lake Tana. On the other hand, the increase of precipitation in wet season makes the wet season wetter and implies higher possibility of flash floods. This will have deleterious consequences in the local community. Therefore, concerned water organizations in local, state, and federal levels shall be prepared to harness the opportunities with more water resources for utilization and management, as well as flood preventive measures.

  15. Regional geomorphic analysis and gis susceptibility mapping of landslides in the blue nile and the tekeze river basins of ethiopia

    NASA Astrophysics Data System (ADS)

    Ismail, Elamin Hassan Dai

    The Plateau region of Ethiopia lies within a seismically active continental extensional regime, which is being rapidly incised by the Blue Nile and the Tekeze Rivers. Extremely large landslides pose serious hazards in this highly populated region (>27 million), which is in the process of developing its hydrologic resources. This research sought to develop cost-effective methods to compile regional landslide inventory and landslide susceptibility maps, using geomorphic tools and GIS technologies. This work also sought to evaluate the relationships between landslide dams and knickpoints, caused by channel bed incision from those caused by slope failures, by utilizing identified knickpoints along 56 tributary channels across the study area. The study employed the weighted overlay technique to produce regional landslide susceptibility hazard maps, and for the first time, employing wind-driven and integrated rainfall/aspect rasters at various inclination to more realistically model the actual precipitation that is felt by hillsides of varying azimuth, shape, and height. Landslides greater than 500m long were tentatively identified on 1:200,000 topographic maps draped over 30m hill-shade generated ASTER GDEMv2. The mapping revealed different types of landslides, and also revealed a considerable number of old, dormant landslide features. The use of wind-driven rainfall with integrated rainfall and aspect rasters provided a much more detailed and asymmetric distribution of precipitation. Spatial distribution of the very high and high hazard areas, during the Kermit and Belg rainy seasons by a range of 0.38% for an inclination of 40o and 1.7% for inclinations on 60o, as compared to the traditional assumption of 90o vertical rainfall, without integration of a slope aspect raster.

  16. Effect of water vapors on the luminescence of cation-exchange membranes modified by Pt(II) and Ru(II) complexes and Nile blue

    NASA Astrophysics Data System (ADS)

    Khakhalina, M. S.; Musaeva, D. N.; Tikhomirova, I. Yu.; Puzyk, M. V.

    2010-04-01

    The surface of a cation-exchange membrane was modified by the [PtEnPpy]+, [PtEnBt]+, [PtEnTpy]+, [RuBpy3]+2, and NB+, (En is ethylenediamine; Ppy, Bt, Tpy are α-deprotonated forms of 2-phenylpyridine, 2-phenylbenzothiazole, and 2-(2'-thienyl)pyridine, respectively; Bpy is 2,2'-bipyridyl, and NB+ is Nile blue) ions, which exhibit intense luminescence. It is found that the quenching of the luminescence of the modified cation-exchange membrane by water vapors depends on the nature of the excited electronic state of the immobilized cation.

  17. Error analysis of global satellite precipitation products using daily gauged observations over the upper central Blue Nile Basin

    NASA Astrophysics Data System (ADS)

    Sahlu, Dejene; Moges, Semu; Anagnostou, Emmanouil N.; Hailu, Dereje

    2015-04-01

    Water resource assessment, planning and management in Africa are often constrained due to lack of reliable spatio-temporal rainfall data. Satellite and global reanalysis products are steadily growing and offering useful alternative datasets of rainfall globally. Aim of this paper is to examine the error characteristics of the main available global satellite precipitation products with the view to improve the reliability of wet season (June to September) rainfall datasets over the upper Blue Nile Basin in Ethiopia. The study utilized six satellite derived precipitation datasets at 0.25-deg spatial grid size and daily temporal resolution:1) the near real-time (3B42_RT) and gauge adjusted (3B42_V7) products of Tropical Rainfall Measuring Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA), 2) gauge adjusted and unadjusted Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks (PERSIANN) products and 3) the gauge adjusted and un-adjusted product of the National Oceanic and Atmospheric Administration (NOAA) Climate Prediction Center Morphing technique (CMORPH) over the period of 2000 to 2013. The historical daily rainfall data sets are chosen for the same period from 64 gauging stations which are within a mountainous area of about 45,000 km2. The elevation of gauges used in this error study ranged from 1800 to 3000 meters above sea level. The error analysis utilized statistical techniques of missed rainfall volume fraction (MRV), falsely detected rainfall volume fraction (FRV), mean relative error (MRE), bias ratio (Bias), coefficient of variation of error (CVE) and the trends of the error metrics with respect to elevation. The three error metrics, MRE, Bias and CVE are further examined for five rainfall thresholds associated with different percentile categories (2nd, 20th, 50th, 80th and 98th) . Results show that CMORPH has relatively lower MRV (~1.5 %) than the TRMM and PERSIANN products (10 -13 %.). Non-gauge adjusted

  18. Spectrophotometric reaction rate method for the determination of trace amounts of vanadium(V) by its catalytic effect on the oxidation of Nile blue with bromate

    SciTech Connect

    Ensafi, A.A.; Amini, M.K.; Mazloum, M.

    1999-07-01

    A kinetic spectrophotometric method for the determination of trace amounts of vanadium(V) is described. It is based on the catalytic action of this ion on the oxidation of Nile blue by bromate, which yields a colorless product in acidic media. The reaction is followed spectrophotometrically by measuring the rate of decrease in absorbance at 585 nm and 30 C. A fixed time method of 4.0 min from initiation of the reaction was used. Vanadium(V) in the range of 0.004--0.520 {micro}g/ml can be determined. The proposed method is hardly subject to interference. The parameters affecting the sensitivity were optimized. The proposed method was used for the determination of vanadium in water and in milk samples.

  19. Coupled hydrologic and land use change models for decision making on land and water resources in the Upper Blue Nile basin

    NASA Astrophysics Data System (ADS)

    Yalew, Seleshi; van der Zaag, Pieter; Mul, Marloes; Uhlenbrook, Stefan; Teferi, Ermias; van Griensven, Ann; van der Kwast, Johannes

    2013-04-01

    Hydrology of a basin, alongside climate change, is well documented to impact and to be impacted by land use/land cover change processes. The need to understand the impacts of hydrology on land use change and vice- versa cannot be overstated especially in basins such as the Upper Blue Nile in Ethiopia, where the vast majority of farmers depend on rain-fed agriculture. A slight fluctuation in rainy seasons or an increase or decrease in magnitude of precipitation can easily trigger drought or flooding. On the other hand, ever growing population and emerging economic development, among others, is likely to continually alter land use/land cover change, thereby affecting hydrological processes. With the intention of identifying and analyzing interactions and future scenarios of the hydrology and land use/land cover, we carried out a case study on a meso-scale catchment, in the Upper Blue Nile basin. A land use model using SITE (SImulation of Terrestrial Environments) was built for analyzing land use trends from aerial land cover photographs of 1957 and simulate until 2009 based on socio-economic as well as biophysical factors. Major land use drivers in the catchment were identified and used as input to the land use model. Separate land use maps were produced using Landsat images of 1972, 1986, 1994 and 2009 for historical calibration of the land use model. By the same token, a hydrological model for the same catchment was built using the SWAT (Soil and Water Assessment Tool) model. After calibration of the two independent models, they were loosely coupled for analyzing the changes in either of the models and impacts on the other. Among other details, the coupled model performed better in identifying limiting factors from both the hydrology as well as from the land use perspectives. For instance, the simulation of the uncoupled land use model alone (without inputs from SWAT on the water budget of each land use parcel) continually considered a land use type such as a wet

  20. Summer Rains and Dry Seasons in the Upper Blue Nile Basin: The Predictability of Half a Century of Past and Future Spatiotemporal Patterns

    PubMed Central

    Mellander, Per-Erik; Gebrehiwot, Solomon G.; Gärdenäs, Annemieke I.; Bewket, Woldeamlak; Bishop, Kevin

    2013-01-01

    During the last 100 years the Ethiopian upper Blue Nile Basin (BNB) has undergone major changes in land use, and is now potentially facing changes in climate. Rainfall over BNB supplies over two-thirds of the water to the Nile and supports a large local population living mainly on subsistence agriculture. Regional food security is sensitive to both the amount and timing of rain and is already an important political challenge that will be further complicated if scenarios of climate change are realized. In this study a simple spatial model of the timing and duration of summer rains (Kiremt) and dry season (Bega), and annual rain over the upper BNB was established from observed data between 1952 and 2004. The model was used to explore potential impacts of climate change on these rains, using a down-scaled ECHAM5/MP1-OM scenario between 2050 and 2100. Over the observed period the amount, onset and duration of Kiremt rains and rain-free Bega days have exhibited a consistent spatial pattern. The spatially averaged annual rainfall was 1490 mm of which 93% was Kiremt rain. The average Kiremt rain and number of rainy days was higher in the southwest (322 days) and decreased towards the north (136 days). Under the 2050–2100 scenario, the annual mean rainfall is predicted to increase by 6% and maintain the same spatial pattern as in the past. A larger change in annual rainfall is expected in the southwest (ca. +130 mm) with a gradually smaller change towards the north (ca. +70 mm). Results highlight the need to account for the characteristic spatiotemporal zonation when planning water management and climate adaptation within the upper BNB. The presented simple spatial resolved models of the presence of Kiremt and annual total rainfall could be used as a baseline for such long-term planning. PMID:23869219

  1. Hydrogeological and hydrochemical framework of Upper Awash River basin, Ethiopia: With special emphasis on inter-basins groundwater transfer between Blue Nile and Awash Rivers

    NASA Astrophysics Data System (ADS)

    Yitbarek, Andarge; Razack, Moumtaz; Ayenew, Tenalem; Zemedagegnehu, Engida; Azagegn, Tilahun

    2012-04-01

    Integrated approach has been used to investigate the hydrogeological framework of a complex fractured volcanic aquifer system in the Upper Awash River basin located at the western shoulder of the Ethiopian Rift. The groundwater flow system and mechanism of recharge of different aquifers have been studied using conventional hydrogeological field investigations, hydrochemistry, and isotope hydrology. Litho-hydrostratigraphic relationships were constructed from lithologic logs obtained from exploratory drilling of deep boreholes. The result indicates quite complex flow pattern and hydraulic characteristics of the different volcanic aquifers. The litho-hydrostratigraphic correlation indicates that the permeable and porous scoraceous lower basaltic aquifer is extended laterally all the way from the Blue Nile Plateau to the study area. New evidences have also emerged on the inter-basin groundwater transfer. Two distinct regional basaltic aquifers (upper and lower) are identified showing distinct hydrochemical and isotopic signatures. In the southern part of the study area the upper and lower aquifers form one unconfined regional aquifer system. In the northern and central part of the basin, it appears that the two systems are separated by regional aquiclude forming confined aquifers, in places with artesian wells. The groundwater from the deep exploratory wells (>250 m) tapping the lower basaltic aquifer and wells located in the south were found to be moderately mineralized (TDS: 400-600 mg/l), with relatively depleted stable isotope composition and with almost zero tritium. In contrast, the upper shallow aquifer has lesser ionic concentration, more isotopically enriched. Evidences from the different methods clearly indicate inter-basin groundwater transfer from the Blue Nile basin to the Upper Awash basin. The evidences also converge to testify common origin of recharge, presence of hydraulic connectivity for systems tapping the lower basaltic aquifer. This has enormous

  2. Nile Delta

    Atmospheric Science Data Center

    2013-04-15

    article title:  The Nile River Delta     View Larger Image ... of eastern Africa. At the apex of the fertile Nile River Delta is the Egyptian capital city of Cairo. To the west are the Great Pyramids ...

  3. Simple and Rapid Differentiation of Mycobacterium tuberculosis H37Ra from M. tuberculosis Clinical Isolates through Two Cytochemical Tests Using Neutral Red and Nile Blue Stains

    PubMed Central

    Soto, Carlos Y.; Andreu, Núria; Gibert, Isidre; Luquin, Marina

    2002-01-01

    The attenuated Mycobacterium tuberculosis strain H37Ra is one of the most commonly used controls for M. tuberculosis identification in the clinical laboratory and is a source of false-positive results for M. tuberculosis as a consequence of cross-contamination. Therefore, the ability to discriminate between H37Ra and real clinical isolates has important public health implications. To date, differentiation of H37Ra from M. tuberculosis clinical isolates is possible only by IS6110 genotyping and spoligotyping. In the 1950s, some authors reported that the virulent strain H37Rv and M. tuberculosis clinical isolates were able to fix basic dyes in their anionic forms, while H37Ra was not. We have studied the different techniques described for M. tuberculosis cytochemical staining and have chosen the best of these, introducing certain modifications in order to increase their discriminative power and reproducibility. We describe cytochemical staining of M. tuberculosis cells with neutral red and Nile blue, which differentiates H37Ra from virulent strains. This method could be used as an easy laboratory tool for distinguishing between H37Ra and real M. tuberculosis clinical isolates. PMID:12149369

  4. Simple and rapid differentiation of Mycobacterium tuberculosis H37Ra from M. tuberculosis clinical isolates through two cytochemical tests using neutral red and nile blue stains.

    PubMed

    Soto, Carlos Y; Andreu, Núria; Gibert, Isidre; Luquin, Marina

    2002-08-01

    The attenuated Mycobacterium tuberculosis strain H37Ra is one of the most commonly used controls for M. tuberculosis identification in the clinical laboratory and is a source of false-positive results for M. tuberculosis as a consequence of cross-contamination. Therefore, the ability to discriminate between H37Ra and real clinical isolates has important public health implications. To date, differentiation of H37Ra from M. tuberculosis clinical isolates is possible only by IS6110 genotyping and spoligotyping. In the 1950s, some authors reported that the virulent strain H37Rv and M. tuberculosis clinical isolates were able to fix basic dyes in their anionic forms, while H37Ra was not. We have studied the different techniques described for M. tuberculosis cytochemical staining and have chosen the best of these, introducing certain modifications in order to increase their discriminative power and reproducibility. We describe cytochemical staining of M. tuberculosis cells with neutral red and Nile blue, which differentiates H37Ra from virulent strains. This method could be used as an easy laboratory tool for distinguishing between H37Ra and real M. tuberculosis clinical isolates.

  5. Designing multi-reservoir system designs via efficient water-energy-food nexus trade-offs - Selecting new hydropower dams for the Blue Nile and Nepal's Koshi Basin

    NASA Astrophysics Data System (ADS)

    Harou, J. J.; Hurford, A.; Geressu, R. T.

    2015-12-01

    Many of the world's multi-reservoir water resource systems are being considered for further development of hydropower and irrigation aiming to meet economic, political and ecological goals. Complex river basins serve many needs so how should the different proposed groupings of reservoirs and their operations be evaluated? How should uncertainty about future supply and demand conditions be factored in? What reservoir designs can meet multiple goals and perform robustly in a context of global change? We propose an optimized multi-criteria screening approach to identify best performing designs, i.e., the selection, size and operating rules of new reservoirs within multi-reservoir systems in a context of deeply uncertain change. Reservoir release operating rules and storage sizes are optimized concurrently for each separate infrastructure design under consideration across many scenarios representing plausible future conditions. Outputs reveal system trade-offs using multi-dimensional scatter plots where each point represents an approximately Pareto-optimal design. The method is applied to proposed Blue Nile River reservoirs in Ethiopia, where trade-offs between capital costs, total and firm energy output, aggregate storage and downstream irrigation and energy provision for the best performing designs are evaluated. The impact of filling period for large reservoirs is considered in a context of hydrological uncertainty. The approach is also applied to the Koshi basin in Nepal where combinations of hydropower storage and run-of-river dams are being considered for investment. We show searching for investment portfolios that meet multiple objectives provides stakeholders with a rich view on the trade-offs inherent in the nexus and how different investment bundles perform differently under plausible futures. Both case-studies show how the proposed approach helps explore and understand the implications of investing in new dams in a global change context.

  6. Effects of land use and land cover on selected soil quality indicators in the headwater area of the Blue Nile basin of Ethiopia.

    PubMed

    Teferi, Ermias; Bewket, Woldeamlak; Simane, Belay

    2016-02-01

    Understanding changes in soil quality resulting from land use and land management changes is important to design sustainable land management plans or interventions. This study evaluated the influence of land use and land cover (LULC) on key soil quality indicators (SQIs) within a small watershed (Jedeb) in the Blue Nile Basin of Ethiopia. Factor analysis based on principal component analysis (PCA) was used to determine different SQIs. Surface (0-15 cm) soil samples with four replications were collected from five main LULC types in the watershed (i.e., natural woody vegetation, plantation forest, grassland, cultivated land, and barren land) and at two elevation classes (upland and midland), and 13 soil properties were measured for each replicate. A factorial (2 × 5) multivariate analysis of variance (MANOVA) showed that LULC and altitude together significantly affected organic matter (OM) levels. However, LULC alone significantly affected bulk density and altitude alone significantly affected bulk density, soil acidity, and silt content. Afforestation of barren land with eucalypt trees can significantly increase the soil OM in the midland part but not in the upland part. Soils under grassland had a significantly higher bulk density than did soils under natural woody vegetation indicating that de-vegetation and conversion to grassland could lead to soil compaction. Thus, the historical LULC change in the Jedeb watershed has resulted in the loss of soil OM and increased soil compaction. The study shows that a land use and management system can be monitored if it degrades or maintains or improves the soil using key soil quality indicators.

  7. Modeling the water budget of the Upper Blue Nile basin using the JGrass-NewAge model system and satellite data

    NASA Astrophysics Data System (ADS)

    Abera, Wuletawu; Formetta, Giuseppe; Brocca, Luca; Rigon, Riccardo

    2017-06-01

    The Upper Blue Nile basin is one of the most data-scarce regions in developing countries, and hence the hydrological information required for informed decision making in water resource management is limited. The hydrological complexity of the basin, tied with the lack of hydrometeorological data, means that most hydrological studies in the region are either restricted to small subbasins where there are relatively better hydrometeorological data available, or on the whole-basin scale but at very coarse timescales and spatial resolutions. In this study we develop a methodology that can improve the state of the art by using available, but sparse, hydrometeorological data and satellite products to obtain the estimates of all the components of the hydrological cycle (precipitation, evapotranspiration, discharge, and storage). To obtain the water-budget closure, we use the JGrass-NewAge system and various remote sensing products. The satellite product SM2R-CCI is used for obtaining the rainfall inputs, SAF EUMETSAT for cloud cover fraction for proper net radiation estimation, GLEAM for comparison with NewAge-estimated evapotranspiration, and GRACE gravimetry data for comparison of the total water storage amounts available in the whole basin. Results are obtained at daily time steps for the period 1994-2009 (16 years), and they can be used as a reference for any water resource development activities in the region. The overall water-budget analysis shows that precipitation of the basin is 1360 ± 230 mm per year. Evapotranspiration accounts for 56 % of the annual water budget, runoff is 33 %, storage varies from -10 to +17 % of the water budget.

  8. Improving satellite quantitative precipitation estimates through the use of high-resolution numerical weather predictions: Similarities and contrasts between the Alps and Blue Nile region

    NASA Astrophysics Data System (ADS)

    Bartsotas, Nikolaos; Nikolopoulos, Efthymios; Anagnostou, Emmanouil; Kallos, George

    2017-04-01

    Estimation of heavy precipitation events (HPEs) over high mountainous terrain is a particularly challenging task due to the limited availability of in-situ observations. Proper analysis and thorough understanding of the charac-teristics of HPE over complex terrain is thus hampered by insufficient precipitation information. Rain gauge networks usually present insufficient density and quality control issues in such areas. Radar rainfall estimates, wherever available, are heavily affected from terrain blockage. In this context, remote sensing has been attributed with a major role. However, this does not come without blemishes, as strong underestimation of precipitation associated with low-level orographic enhancement, introduces significant error in satellite estimates. In this study, we evaluate a satellite precipitation error-correction approach that can be implemented in the ab-sence of ground observations and it is based on utilization of precipitation information from high-resolution (1-2km) NWP simulations. Two quasi-global satellite precipitation products (CMORPH-8km and PERSIANN-4km) are used in more than 20 identified HPEs over two mountainous areas, the Alps and Ethiopia's Blue Nile. High-resolution atmospheric simulations from RAMS/ICLAMS are evaluated against rain gauge networks and radar estimates, then utilized to derive error correction functions for corresponding satellite precipitation data. Consequently, a PDF matching is applied and conclusions on the dependence of the method from synoptic at-mospheric conditions, which reveal to a certain degree the predictability of error properties, as well as the possi-bility of a global approach, are thoroughly discussed.

  9. Evaluation of climate anomalies impacts on the Upper Blue Nile Basin in Ethiopia using a distributed and a lumped hydrologic model

    NASA Astrophysics Data System (ADS)

    Elsanabary, Mohamed Helmy; Gan, Thian Yew

    2015-11-01

    Evaluating the climate anomalies impacts on the Upper Blue Nile Basin (UBNB), Ethiopia, a large basin with scarce hydroclimatic data, through hydrologic modeling is a challenge. A fully distributed, physically-based model, a modified version of the Interactions Soil-Biosphere Atmosphere model of Météo France (MISBA), and a lumped, conceptual rainfall-runoff Sacramento model, SAC-SMA of the US National Weather Service, were used to simulate the streamflow of UBNB. To study the potential hydrologic effect of climate anomalies on the UBNB, rainfall and temperature data observed when climate anomalies were active, were resampled and used to drive MISBA and SAC-SMA. To obtain representative, distributed precipitation data in mountainous basins, it was found that a 3% adjustment factor for every 25 m rise in elevation was needed to orographically correct the rainfall over UBNB. The performance of MISBA applied to UBNB improved after MISBA was modified so that it could simulate evaporation loss from the canopy, providing coefficient of determination (R2) = 0.58, and root mean square error (RMSE) = 0.34 m3/s in comparison with the observed streamflow. In contrast, the performance of SAC-SMA at the calibration run and the validation run is better than that of MISBA, such that R2 is 0.79 for calibration and 0.82 for validation even though it models the hydrology of UBNB in a lumped, conceptual framework as against the physically-based, fully distributed framework of MISBA. El Niño tends to decrease the June-September rainfall but increase the February-May rainfall, while La Niña has opposite effect on the rainfall of UBNB. Based on the simulations of MISBA and SAC-SMA for UBNB, La Niña and Indian Ocean Dipole (IOD) tend to have a wetting effect while El Niño has a drying effect on the streamflow of the UBNB. In addition, El Niño Southern Oscillation (ENSO) and IOD increase the streamflow variability more than changing the magnitude of streamflow. The results provide

  10. Determining the Palaeodrainage of the Nile River from a Provenance Study of the Nile Delta Cone Sediments

    NASA Astrophysics Data System (ADS)

    Fielding, L.; Najman, Y.; Millar, I.; Butterworth, P.; Garzanti, E.; Kneller, B. C.

    2014-12-01

    This study documents the palaeodrainage history of the Nile River, in particular the time of its transition from a small locally sourced drainage network to the initiation of an extensive catchment. Today, the Nile drains as far south as Lake Victoria, with the White Nile draining largely cratonic rocks of Archean to Proterozoic age and the Blue Nile draining Cenozoic Ethiopian Continental Flood Basalts and Neoproterozoic basement. However, the timing of catchment expansion to the river's current extent is highly debated. Two end member models are: A) The Blue Nile did not connect with the lower Nile until the Late Messinian, and the White Nile not until 0.5 Ma. In this model, the pre-Messinian Nile delta sediments are locally derived from the Red Sea Hills (RSH) (Issawi and McCauley 1992). B) The Blue Nile has been connected to the lower Nile since the Oligocene (Burke and Wells 1989). Onshore fieldwork characterised each possible source area (Ethiopian flood basalts, Archean craton, and Neoproterozoic basement and Phanerozoic cover sequences of the RSH) using petrography, geochemistry and isotope studies. Tertiary-aged Nile delta sediments provide a unique archive of the river's palaeodrainage history, which were analysed from conventional core from exploration and appraisal wells in order to identify the occurrence (if any) of these sources in the delta geological record. Heavy mineral, petrographic, U/Pb rutile and Lu/Hf zircon analyses indicate Blue Nile and/or RSH input to the Nile delta since at least the Oligocene with very little input from the White Nile. Sr and Nd whole-rock analyses of mud samples allow discrimination between the Blue Nile and RSH sources and may, subject to further analyses, confirm Blue Nile input to the delta since the Oligocene. U-Pb zircon analyses reveal the presence of 20-30 Ma zircons in both the modern river sediments from the Ethiopian Highlands and the Nile Delta core from the early Miocene to present day indicating a

  11. Determining the palaeodrainage of the Nile river from a provenance study of the Nile delta cone sediments

    NASA Astrophysics Data System (ADS)

    Fielding, Laura; Najman, Yani; Millar, Ian; Butterworth, Peter; Garzanti, Eduardo; Kneller, Ben

    2014-05-01

    This study documents the palaeodrainage history of the Nile River, in particular the time of its transition from a small locally sourced drainage network to the initiation of an extensive catchment. Today, the Nile drains as far south as Lake Victoria, with the White Nile draining largely cratonic rocks of Archean to Proterozoic age and the Blue Nile draining Cenozoic Ethiopian Continental Flood Basalts and Neoproterozoic basement. However, the timing of catchment expansion to the river's current extent is highly debated. Two end member models are: A) The Blue Nile did not connect with the lower Nile until the Late Messinian, and the White Nile not until 0.5 Ma. In this model, the pre-Messinian Nile delta sediments are locally derived from the Red Sea Hills (RSH) (Issawi and McCauley 1992). B) The Blue Nile has been connected to the lower Nile since the Oligocene (Burke and Wells 1989). Onshore fieldwork characterised each possible source area (Ethiopian flood basalts, Archean craton, and Neoproterozoic basement and Phanerozoic cover sequences of the RSH) using petrography, geochemistry and isotope studies. Tertiary-aged Nile delta sediments provide a unique archive of the river's palaeodrainage history, which were analysed from conventional core from exploration and appraisal wells in order to identify the occurrence (if any) of these sources in the delta geological record. Heavy mineral, petrographic, U/Pb rutile and Lu/Hf zircon analyses indicate Blue Nile and/or RSH input to the Nile delta since at least the Oligocene with very little input from the White Nile. Sr and Nd whole-rock analyses of mud samples allow discrimination between the Blue Nile and RSH sources and may, subject to further analyses, confirm Blue Nile input to the delta since the Oligocene. U-Pb zircon analyses reveal the presence of 20-30 Ma zircons in both the modern river sediments from the Ethiopian Highlands and the Nile Delta core from the early Miocene to present day indicating a

  12. The Project for Developing Countermeasures against Landslides in the Abay River Gorge, Ethiopia

    NASA Astrophysics Data System (ADS)

    Guta, H. E.

    2016-12-01

    The Blue Nile Gorge of Ethiopia is characterized by high relief landscape. The stretch of major arterial road that connects Ethiopia to Sudan passes through the Gorge. The Gorge is plagued by swarms of landslides which makes it a tremendous obstacle for travel and communication. Therefore, landside study was carried out from 2010 to 2012 by JICA and Geological survey of Ethiopia to figure out the mechanisms that trigger the swarms of landslides that occur in the area and identify appropriate countermeasures that would be best implemented. The study included geomorphologic and geologic survey, drilling survey, displacement monitoring, ground water and precipitation monitoring, geophysical exploration, and stability analysis. About 42 landslide monitoring instruments namely extensometers (both surface and borehole), inclinometers and ground water level meters were installed in four highly landslide prone areas to detect slip surface, and determine amount and direction of movement. The amount of landslide movement at the four zones is 42.4, 57.6, 294.9 and 136mm during rainy season. Ground water level rising, nature of material and intense rainfall are found to be among the major triggering factors. Stability analysis using Simple Jambu and modified Fellenus methods was conducted resulting in safety factor Fs less than one and reasonably 0.98 by adopting shear parameters of soils by back analysis. By assuming cohesion (c') to be very close to 0 due to landslide blocks active movement when ground water rises during rainy season, Shear resistance angle, ɸ, was obtained to be 10.80, 26.30, 10.20 and 16.30 in the four areas using Modified Fellenius method and 10.70, 26.60, 10.00 and 16.10 using Simple Janbu method. Effect of countermeasures was checked by trial calculation. Accordingly the factory of safety increased from 0.98 to 1.2 when ɸ=60, ground water is lowered by 6m, and steel pipe pile of ɸ500mm x t40mm at an interval of 1.9m are implemented. consequently

  13. The Nile

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This image of the northern portion of the Nile River was captured by MISR's nadir camera on January 30, 2001 (Terra orbit 5956). The Nile is the longest river in the world, extending for about 6700 kilometers from its headwaters in the highlands of eastern Africa.

    At the apex of the fertile Nile River Delta is the Egyptian capital city of Cairo. To the west are the Great Pyramids of Giza. North of here the Nile branches into two distributaries, the Rosetta to the west and the Damietta to the east.

    Also visible in this image is the Suez Canal, a shipping waterway connecting Port Said on the Mediterranean Sea with the Gulf of Suez. The Gulf is an arm of the Red Sea, and is located on the righthand side of the picture.

    MISR was built and is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Office of Earth Science, Washington, DC. The Terra satellite is managed by NASA's Goddard Space Flight Center, Greenbelt, MD. JPL is a division of the California Institute of Technology.

  14. The Nile

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This image of the northern portion of the Nile River was captured by MISR's nadir camera on January 30, 2001 (Terra orbit 5956). The Nile is the longest river in the world, extending for about 6700 kilometers from its headwaters in the highlands of eastern Africa.

    At the apex of the fertile Nile River Delta is the Egyptian capital city of Cairo. To the west are the Great Pyramids of Giza. North of here the Nile branches into two distributaries, the Rosetta to the west and the Damietta to the east.

    Also visible in this image is the Suez Canal, a shipping waterway connecting Port Said on the Mediterranean Sea with the Gulf of Suez. The Gulf is an arm of the Red Sea, and is located on the righthand side of the picture.

    MISR was built and is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Office of Earth Science, Washington, DC. The Terra satellite is managed by NASA's Goddard Space Flight Center, Greenbelt, MD. JPL is a division of the California Institute of Technology.

  15. Nile River

    Atmospheric Science Data Center

    2013-04-15

    ... extent of the Nile waters before and after the onset of the rainy seasons of 2000 (top pair) and 2001 (bottom pair). The images are ... poor prior to the flooding due to a late start of the rainy season in parts of the country. Following two consecutive years of serious ...

  16. 20,000 years of Nile River dynamics and environmental changes in the Nile catchment area as inferred from Nile upper continental slope sediments

    NASA Astrophysics Data System (ADS)

    Revel, Marie; Ducassou, E.; Skonieczny, C.; Colin, C.; Bastian, L.; Bosch, D.; Migeon, S.; Mascle, J.

    2015-12-01

    Multi-proxy analysis of two marine sediment cores (MS27PT and MD04-2726) from the Nile continental slope provides evidence of changes in Nile sediment discharge related to changes in Ethiopian African Monsoon (EAM) precipitation, and allows us to reconstruct changes in Nile River runoff, vegetation and erosion in the Nile headwaters. Sediment element composition and neodymium isotopic composition reveal significant changes in clastic sediment provenance, with sources oscillating between a Saharan aeolian contribution during the Last Glacial Maximum/deglacial transition and during the Late Holocene, and a Blue/Atbara Nile fluvial contribution during the African Humid Period (AHP). This study provides a new understanding of past environmental changes. Between 14.6 and 14.13 ka there was a major input of sediments from the Ethiopian Highlands, consistent with a stronger EAM at that time. Climate in the Nile basin was wetter between 14.8 and 8.4 ka, with a corresponding increase in Blue Nile water and sediment discharge via the main Nile into the Eastern Mediterranean. The gradual climatic transition from the AHP to the present-day dry climate was reflected in a decrease in Blue Nile sediment deposition and flood discharge between 8.4 and 3.7 ka, with aridity at a maximum between 3.7 and 2.6 ka. The onset of drier conditions in the Blue Nile basin seems to have begun before the 8.2 ka cooling event in the North Atlantic. We speculate that the climatic change from the wet AHP to the dry late Holocene may have been a result of a break in the low latitude dynamic equilibrium between climate, vegetation and erosion, which may in turn have affected the climate in higher latitudes. Reduced Nile flow may also have had an impact on Levantine Intermediate Water originating in the Eastern Mediterranean through an increase in intermediate water formation.

  17. Geochemistry of sediments and surface soils from the Nile Delta and lower Nile valley studied by epithermal neutron activation analysis

    NASA Astrophysics Data System (ADS)

    Arafa, Wafaa M.; Badawy, Wael M.; Fahmi, Naglaa M.; Ali, Khaled; Gad, Mohamed S.; Duliu, Octavian G.; Frontasyeva, Marina V.; Steinnes, Eiliv

    2015-07-01

    The distributions of 36 major and trace elements in 40 surface soil and sediment samples collected from the Egyptian section of the river Nile were determined by epithermal neutron activation analysis and compared with corresponding data for the Upper Continental Crust and North American Shale Composite. Their relative distributions indicate the presence of detrital material of igneous origin, most probably resulting from weathering on Ethiopian highlands and transported by the Blue Nile, the Nile main tributary. The distributions of the nickel, zinc, and arsenic contents suggest that the lower part of the Nile and its surroundings including the Nile Delta is not seriously polluted with metals from local human activity. The geographical distributions of Na, Cl, and I as well as results of principal component analysis suggest atmospheric supply of these elements from the ocean. In general the present data may contribute to a better understanding of the geochemistry of the Nile sediments.

  18. Shifting Sediment Sources in the Quaternary Nile

    NASA Astrophysics Data System (ADS)

    Woodward, Jamie; Macklin, Mark; Fielding, Laura; Millar, Ian; Williams, Martin

    2016-04-01

    Invited Paper The Nile basin contains the longest river channel system in the world and drains about one tenth of the African continent. A dominant characteristic of the modern Nile is the marked spatial and temporal variability in the flux of water and sediment. Because the major headwater basins of the Nile are linked to key elements of the global climate system, the sedimentary records in the basin have attracted good deal of attention from the Quaternary palaeoclimate and palaeohydrology communities. Various approaches (from heavy minerals to strontium isotopes) have been employed to examine present and past patterns of sediment yield in the basin. A good deal of work has been carried out on the long sediment records in the delta and offshore which provide high resolution archives of hydrological changes in the upstream basin as well fluctuations in the input of dust from the desert. The sediment load of the modern desert Nile (downstream of Khartoum) is dominated by sediment inputs from the Blue Nile (61 +/- 5%) and Atbara (35 +/- 4%), whilst the White Nile contribution is meagre (3 +/- 2%) (Padoan et al. 2011). Recent work has shown that these values were very different during humid phases of the Quaternary when stronger Northern Hemisphere summer insolation produced wetter conditions across North Africa. In the early Holocene, for example, the Nile floodplain in Northern Sudan shows a tributary wadi input of 40-50%. This paper will review three decades of work on the sediment delivery dynamics of the Quaternary Nile and explore their palaeoclimatic implications. Padoan, M., Garzanti, E., Harlavan, Y., Villa, I.M. (2011) Tracing Nile sediment sources by Sr and Nd isotope signatures (Uganda, Ethiopia, Sudan). Geochim. Cosmochim. Acta 75 (12), 3627-3644.

  19. Nile River Fluctuations Near Khartoum, Sudan

    NASA Image and Video Library

    2001-08-29

    Throughout history, the rising and falling waters of the mighty Nile River have directly impacted the lives of the people who live along its banks. These images of the area around Sudan's capital city of Khartoum capture the river's dynamic nature. Acquired by the Multi-angle Imaging SpectroRadiometer's nadir (vertical-viewing) camera, they display the extent of the Nile waters before and after the onset of the rainy seasons of 2000 (top pair) and 2001 (bottom pair). The images are displayed in "false color," using the camera's near-infrared, green, and blue bands. With this particular spectral combination, water appears in shades of blue and turquoise, and highly vegetated areas show up as bright red. Originating in Uganda and Ethiopia, respectively, the waters of the White Nile (western branch) and Blue Nile (eastern branch) converge at Khartoum (about half-way between image center and the left-hand side), and continue to flow northward as the Great Nile. Although the most obvious feature in these images is the increased width of the White Nile between spring and summer, careful inspection shows that the Great Nile is at its widest in August 2001 (note in particular the area between the clouds near the top of this panel). Heavy rains in the Blue Nile catchment area of the Ethiopian highlands led to a rapid overflow of the river's floodwaters into the main stream of the Great Nile, leading to extensive flooding, the worst effects of which occurred north of Khartoum. According to the Food and Agriculture Organization of the United Nations, tens of thousands of people have fled their homes, and the number of people in need of urgent food assistance in Sudan, estimated at three million earlier in the year, was likely to increase with the onset of these floods. South of the confluence of the White Nile and the Blue Nile, the area of a cross-hatched appearance is the irrigated plain of El Gezira. The Gezira irrigation scheme uses water from the Makwar Dam (now called

  20. West Nile virus

    MedlinePlus

    ... believe West Nile virus is spread when a mosquito bites an infected bird and then bites a ... avoid getting West Nile virus infection after a mosquito bite. People in good health generally do not ...

  1. Risky Sexual Behaviors among Female Youth in Tiss Abay, a Semi-Urban Area of the Amhara Region, Ethiopia

    PubMed Central

    Tadesse, Gojjam; Yakob, Bereket

    2015-01-01

    Background Little is known about sexual risks and associated factors about female youths in semi-urban areas of Ethiopia. This study aimed to describe the nature and magnitude of risky sexual behaviors, and the socio-demographic and behavioral determinants among female youths in Tiss Abay, a semi-urban area on the outskirts of Bahir Dar City of the Amhara Region in northern Ethiopia. Methods A cross-sectional census type study was conducted among female youths who were unmarried and aged 15–29 years in September 2011. Results 711 female youths participated in the study, with the mean age of initiation of sex of 78.6% being16.73±2.53 years. Only 52(9.3%) used condom during the first sex. Within the last 12 months, 509(71.6%) had sexual intercourse and 278(54.6%) had two or more sex partners, and 316(62.1%) did not use condom during their last sex. Sex under the influence of substances was reported by 350(68.8%), and a third of the recent sexes were against the will of participants. One or more risky sexual practices were reported by 503(70.3%) participants, including: multiple sexual partnerships, inconsistently using or not using condoms, sex under the influence of alcohol and/or sex immediately after watching pornography. Age group, current marital status, drinking homemade alcohol, chewing ‘khat’, watching pornography and using any form of stimulant substances were the predictors of risky sexual behavior. Watching pornography before sex and sex for transaction were the predicators of not using condom during most recent sex. Conclusions Risky sexual behaviors were very common among the female youths in Tiss Abay. Initiation of context-based interventions, such as raising awareness about the risks, safer sex practices, condom promotion and integration of gender issues in the programs are recommended. PMID:25738508

  2. Water balance dynamics in the Nile Basin

    USGS Publications Warehouse

    Senay, Gabriel B.; Asante, Kwabena; Artan, Guleid A.

    2009-01-01

    Understanding the temporal and spatial dynamics of key water balance components of the Nile River will provide important information for the management of its water resources. This study used satellite-derived rainfall and other key weather variables derived from the Global Data Assimilation System to estimate and map the distribution of rainfall, actual evapotranspiration (ETa), and runoff. Daily water balance components were modelled in a grid-cell environment at 0·1 degree (∼10 km) spatial resolution for 7 years from 2001 through 2007. Annual maps of the key water balance components and derived variables such as runoff and ETa as a percent of rainfall were produced. Generally, the spatial patterns of rainfall and ETa indicate high values in the upstream watersheds (Uganda, southern Sudan, and southwestern Ethiopia) and low values in the downstream watersheds. However, runoff as a percent of rainfall is much higher in the Ethiopian highlands around the Blue Nile subwatershed. The analysis also showed the possible impact of land degradation in the Ethiopian highlands in reducing ETa magnitudes despite the availability of sufficient rainfall. Although the model estimates require field validation for the different subwatersheds, the runoff volume estimate for the Blue Nile subwatershed is within 7·0% of a figure reported from an earlier study. Further research is required for a thorough validation of the results and their integration with ecohydrologic models for better management of water and land resources in the various Nile Basin ecosystems.

  3. Integral view of Holocene precipitation and vegetation changes in the Nile catchment area as inferred from its delta sediments

    NASA Astrophysics Data System (ADS)

    Hennekam, Rick; Donders, Timme H.; Zwiep, Karin; de Lange, Gert J.

    2015-12-01

    We compare geochemical and pollen data of several well-dated, high-resolution cores to provide an integral Holocene overview of Nile outflow, sedimentation, and vegetation in and around the Nile delta. We show that the focus point of the Nile plume varied considerably, as indicated by planktonic foraminifer Globigerinoides ruber oxygen isotopes tracing Nile discharge differences in an east-west delta transect. At 13-11.5 cal kyr BP, Nile discharge was low and runoff was predominantly directed to the western part of the delta. Sediment arriving in the delta during that period was dominated by Ethiopian Highland (∼Blue Nile) material, shown by high Ti/Al values of the bulk sediment, indicating dry conditions in the source area of the Blue Nile. Nile discharge increased from ∼11.5 cal kyr BP, and was high across the whole delta from ∼10-6.5 cal kyr BP. During this time, the Ti/Al values decreased within most Nile-delta sediments, suggesting that the relative contribution of Blue-Nile sediment decreased. This was likely due to an increased vegetation cover causing diminished erosion in the Ethiopian Highlands. Nile discharge gradually decreased from ∼6.5 cal kyr BP to present. This decrease was more abrupt in the Western Province of the delta and became more gradual towards the east as the shrinking Nile runoff was directed there. The gradual decrease in precipitation in the Nile catchment area seems not to be matched by a gradual response in vegetation growing around the river plain in the lower Nile catchment. Our findings suggest a nonlinear response of northeast African vegetation to precipitation from the middle to late Holocene.

  4. [West Nile fever].

    PubMed

    Takasaki, Tomohiko

    2005-12-01

    West Nile virus was first detected in North America in 1999 and has spread throughout the United States and Canada and into Mexico and the Caribbean. The cases of encephalitis in New York were diagnosed as Saint Louis encephalitis which was endemic in the North America. However, dead crows and dead flamingo were found around the same time in New York. American birds seldom die by Saint Louis encephalitis virus infection. According to viral isolation and sequencing of the genome, the causative agent of unknown encephalitis was West Nile virus which was a member of Flaviviridae which cause fever, meningitis and encephalitis. West Nile virus is still active in North America in summer season, 1999 -2005. CDC enlightens people how to protect themselves and their community from West Nile virus. There are some reports that West Nile viral infections were occurred by blood transfusion, biologic products from blood and organ transfusion.

  5. Late Quaternary environments and prehistoric occupation in the lower White Nile valley, central Sudan

    NASA Astrophysics Data System (ADS)

    Williams, Martin A. J.; Usai, Donatella; Salvatori, Sandro; Williams, Frances M.; Zerboni, Andrea; Maritan, Lara; Linseele, Veerle

    2015-12-01

    Despite the major contributions provided over fifty years ago by A.J. Arkell and J.D. Tothill to our understanding of late Quaternary environments and prehistoric occupation near the confluence of the Blue and White Nile in central Sudan, three key questions have remained unresolved since then. (a) Was the decline in Nile flood levels from early Holocene times onwards caused by a reduction in Nile discharge, or by channel incision, or both? (b) Was the regional climate wetter during times of high Nile floods and drier during times of low Nile floods? (c) Given the high degree of disturbance of Mesolithic and later prehistoric sites, is it possible to identify primary-context, stratified and undisturbed occupation? Drawing upon dated evidence from three sites to the east of and three to the west of the lower White Nile, we provide a qualified answer to the first question and documented affirmative answers to the second and third questions.

  6. FAQ: General Questions about West Nile Virus

    MedlinePlus

    ... Related Links Mosquito Surveillance Software General Questions About West Nile Virus Recommend on Facebook Tweet Share Compartir ... numbers of West Nile virus cases? What is West Nile virus? West Nile virus is an arthropod- ...

  7. A detrital record of the Nile River and its catchment

    NASA Astrophysics Data System (ADS)

    Fielding, Laura; Najman, Yani; Millar, Ian; Butterworth, Peter; Ando, Sergio; Padoan, Marta; Barfod, Dan; Kneller, Ben

    2017-04-01

    This research uses analyses from Nile catchment rivers, wadis, dunes and bedrocks to constrain the geological history of NE Africa and document influences on the composition of sediment reaching the Nile delta. Methods used include single grain analyses (U-Pb and Hf analyses of zircon, U-Pb dating of rutile, Ar-Ar dating of white mica and plagioclase), and bulk analyses (petrography, Sr, Nd and Hf isotopic analyses, and trace element concentrations). Our data show evolution of the North African crust, highlighting phases in the development of the Arabian-Nubian Shield and amalgamation of Gondwana in Neoproterozoic times. The Saharan Metacraton and Congo Craton in Uganda have a common history of crustal growth, with new crust formation at 3.0 - 3.5 Ga, and crustal melting at c. 2.7 Ga. The Hammamat Formation of the Arabian-Nubian Shield is locally derived and has a maximum depositional age of 635 Ma. By contrast, Phanerozoic sedimentary rocks are derived from more distant sources. In the modern Nile drainage, there is considerable evolution downstream, controlled predominantly by changes in local geology and geomorphology. The provenance signature of the White Nile is dramatically different upstream and downstream of the Sudd marshes as a result of sediment trapping. South of the Sudd, White Nile sediments are craton-derived. North of the Sudd, at Kosti, the signature of the White Nile is dominated by material derived from Phanerozoic sandstones supplied via alluvial fans to the west of the river. Further north, south of Khartoum, White Nile sediment composition is affected by its proximity to the Pleistocene Blue Nile sourced Gezira Fan. The Blue Nile's and Atbara's signatures are influenced predominantly by input from the Ethiopian flood basalts in terms of their bulk-rock signature, and by proximity to the Arabian-Nubian Shield in terms of zircon characteristics. A further shift in sediment signature in terms of zircon characteristics is seen by the time the Nile

  8. The Nile River

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This image of the northern portion of the Nile River was captured by MISR's nadir camera on January 30, 2001 (Terra orbit 5956). The Nile is the longest river in the world, extending for about 6700 kilometers from its headwaters in the highlands of eastern Africa. At the apex of the fertile Nile River Delta is the Egyptian capital city of Cairo. To the west are the Great Pyramids of Giza. North of here the Nile branches into two distributaries, the Rosetta to the west and the Damietta to the east. Also visible in this image is the Suez Canal, a shipping waterway connecting Port Said on the Mediterranean Sea with the Gulf of Suez. The Gulf is an arm of the Red Sea, and is located on the righthand side of the picture. Image credit: NASA/GSFC/LaRC/JPL, MISR Team.

  9. The Nile River

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This image of the northern portion of the Nile River was captured by MISR's nadir camera on January 30, 2001 (Terra orbit 5956). The Nile is the longest river in the world, extending for about 6700 kilometers from its headwaters in the highlands of eastern Africa. At the apex of the fertile Nile River Delta is the Egyptian capital city of Cairo. To the west are the Great Pyramids of Giza. North of here the Nile branches into two distributaries, the Rosetta to the west and the Damietta to the east. Also visible in this image is the Suez Canal, a shipping waterway connecting Port Said on the Mediterranean Sea with the Gulf of Suez. The Gulf is an arm of the Red Sea, and is located on the righthand side of the picture. Image credit: NASA/GSFC/LaRC/JPL, MISR Team.

  10. West Nile Virus

    MedlinePlus

    ... strategies visit the MedlinePlus West Nile virus site . Credit: Credit: CDC This is an enlarged view of a ... The End of an Era Acknowledgments References Photo Credits Dr. Joseph Kinyoun: Selected Bibliography NIAID 60th Anniversary ...

  11. West Nile Virus

    MedlinePlus

    ... you'll be infected with West Nile virus, mosquito bites can still be an itchy nuisance. The CDC advises people to protect themselves from mosquito bites by using mosquito repellent, especially at times ...

  12. 10. GENERAL VIEW OF NILES TREAD LATHE, Niles Tool Company, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. GENERAL VIEW OF NILES TREAD LATHE, Niles Tool Company, Hamilton, Ohio. - Juniata Shops, Erecting Shop & Machine Shop, East of Fourth Avenue, between Fourth & Fifth Streets, Altoona, Blair County, PA

  13. A White Nile megalake during the last interglacial period

    NASA Astrophysics Data System (ADS)

    Barrows, Timothy T.; Williams, Martin A. J.; Mills, Stephanie C.; Duller, Geoff A. T.; Fifield, L. Keith; Haberlah, David; Tims, Stephen G.; Williams, Frances M.

    2014-05-01

    The eastern Sahara Desert of Africa is one of the most climatically sensitive areas on Earth, varying from lake-studded savannah woodland to hyperarid desert over the course of a glacial-interglacial cycle. In currently semiarid Sudan there is widespread evidence that a very large freshwater lake once filled the White Nile River valley (Barrows et al., 2014). Here we present the first quantitative estimate for the dimensions of the lake and a direct age for the emplacement of its shoreline. Using a profile dating approach with the cosmogenic nuclide 10Be, we estimate an exposure age of 109 ± 8 ka for this megalake, indicating that it probably formed during the last interglacial period. This age is supported by optically stimulated luminescence dating of Blue Nile paleochannels associated with the lake. Using a high-resolution digital elevation model, we estimate that the lake was more than 45,000 km2 in area, making it comparable to the largest freshwater lakes on Earth today. We attribute the lake's existence to seasonal flood pulses as a result of local damming of the White Nile by a more southern position of the Blue Nile and greatly increased precipitation associated with an enhanced monsoon. References Barrows, T.T., Williams, M.A.J., Mills, S.C., Duller, G.A.T., Fifield, L.K., Haberlah, D., Tims, S.G., Williams, F.M., 2014. A White Nile megalake during the last interglacial period. Geology. 10.1130/g35238.1

  14. Effects of the Indian Ocean Temperature on Nile River Flow Volumes

    NASA Astrophysics Data System (ADS)

    Becker, R.; Sultan, M.; Becker, D.

    2009-12-01

    Egypt and Sudan are heavily dependent on the Nile River for sustaining their populations. In high flow years, the Lake Nasser surface water levels rise and overflows filling surrounding natural depressions and forming additional lakes (Tushka lakes) in peak flow years. The underlying Nubian Aquifer is recharged in high flow yeas, whereas the Nubian groundwater discharges into the Nile in low flow years. Previous studies have shown that the variability in flow volumes in the Nile River can be partially (~30%) accounted for by variations in the intensity of El Niño Southern Oscillation (ENSO) events. Other previous studies suggested that rainfall in the upper Blue Nile catchment in Sudan can be linked to changes in the intensity of temperature variations across the Indian Ocean (the Indian Ocean Dipole or IOD). To test which of these events correlate best with Nile flow volumes, Nile flow records in the Blue Nile (above Khartoum), the White Nile (above Kharthoum), and combined flow at Wadi Halfa covering the time period from 1902 to 1962 were analyzed together with SST measurements. Peak and minimum discharge, and quarterly measurement from each gauge were obtained. The intensity of El Nino 3.4 and 4, and of the Indian Ocean Dipole variations from the reconstructed SST dataset hadlSST covering the same time period were used. The best correlation was found to exist between fluctuations in the IOD in the Spring (Apr-May-Jun) preceding the peak flow (usually occurring in August) and maximum discharge at the Blue Nile Gauge above Khartoum (Correlation coefficient of 0.65). Variations in El Nino intensity for the same time period showed lower correlations with peak and base Nile flow in the Blue Nile (0.55). This indicates that the intensity of the Indian Ocean Dipole has been a better predictor than El Nino for peak Nile Flow volume. Results highlight the potential for using the latter relationship for predicting Nile Flow volumes flowing in Lake Nasser and for modeling

  15. The Nile Delta, Egypt

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This pair of true- and false-color images from the Moderate Resolution Imaging Spectroradiometer was acquired on June 3, 2002. The fertile land along the Nile River supports lush green vegetation, amid the desert landscape. At its delta at the Mediterranean Sea, the Nile broadens into a large fan-shaped delta. All of Egypt's large cities fall along the Nile, which sustains life in a region of scant rainfall. At the point where the river widens into the delta, a grayish cluster of pixels marks the location of Cairo. To the east is the Sinai Peninsula, whose impermanent water courses create silvery streaks on the pale brown, arid landscape. At lower right is the Red Sea. Credit: Jacques Descloitres, MODIS Land Rapid Response Team, NASA/GSFC

  16. Nile River Delta, Egypt

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The Nile River Delta of Egypt (30.0N, 31.0E) irrigated by the Nile River and its many distributaries, is some of the richest farm land in the world and home to some 45 million people, over half of Egypt's population. The capital city of Cairo is at the apex of the delta. Just across the river from Cairo can be seen the ancient three big pyramids and sphinx at Giza and the Suez Canal is just to the right of the delta.

  17. Nile Delta, Egypt

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The Nile Delta of Egypt (30.0N, 31.0E) irrigated by the Nile River and its many distributaries, is some of the richest farm land in the world and home to some 45 million people, over half of Egypt's population of 57 million. The capital city of Cairo is at the apex of the delta in the middle of the scene. Across the river from Cairo can be seen the three big pyramids and sphinx at Giza and the Suez Canal is just to the right of the delta.

  18. Nile River Delta, Egypt

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The Nile River Delta of Egypt (30.0N, 31.0E) irrigated by the Nile River and its many distributaries, is some of the richest farm land in the world and home to some 45 million people, over half of Egypt's population. The capital city of Cairo is at the apex of the delta. Just across the river from Cairo can be seen the ancient three big pyramids and sphinx at Giza and the Suez Canal is just to the right of the delta.

  19. Nile River Delta, Egypt

    NASA Image and Video Library

    1984-10-13

    The Nile River Delta of Egypt (30.0N, 31.0E) irrigated by the Nile River and its many distributaries, is some of the richest farm land in the world and home to some 45 million people, over half of Egypt's population. The capital city of Cairo is at the apex of the delta. Just across the river from Cairo can be seen the ancient three big pyramids and sphinx at Giza and the Suez Canal is just to the right of the delta.

  20. Discover the Nile River

    ERIC Educational Resources Information Center

    Project WET Foundation, 2009

    2009-01-01

    Bordering on the Fantastic. As the longest river on earth, the Nile passes through 10 countries. Presented through a wide range of activities and a winning array of games, it's also unsurpassed at taking young minds into exploring the world of water, as well as natural and man made wonders.

  1. West Nile Virus

    MedlinePlus

    ... spread by mosquitoes. Mosquitoes become infected by biting birds that carry the virus. People can get West Nile virus when an infected mosquito bites them. This happens most often in the warm-weather months of spring, summer and early fall. You ...

  2. Discover the Nile River

    ERIC Educational Resources Information Center

    Project WET Foundation, 2009

    2009-01-01

    Bordering on the Fantastic. As the longest river on earth, the Nile passes through 10 countries. Presented through a wide range of activities and a winning array of games, it's also unsurpassed at taking young minds into exploring the world of water, as well as natural and man made wonders.

  3. FAQ: West Nile Virus and Dead Birds

    MedlinePlus

    ... Education Public Service Videos West Nile Virus & Dead Birds Recommend on Facebook Tweet Share Compartir On This ... dead bird sightings to local authorities. How do birds get infected with West Nile virus? West Nile ...

  4. Determinants of intimate partner violence during pregnancy among married women in Abay Chomen district, Western Ethiopia: a community based cross sectional study.

    PubMed

    Abebe Abate, Bedilu; Admassu Wossen, Bitiya; Tilahun Degfie, Tizta

    2016-03-10

    Intimate partner violence during pregnancy is the most common form of violence that harms the health of women and the fetus but practiced commonly in developing countries. There is scarcity of information regarding intimate partner violence during pregnancy in Ethiopia. Thus, this study aimed to assess the prevalence and associated factors of intimate partner violence during recent pregnancy in Abay Chomen district, Western Ethiopia. Community based cross sectional study was conducted among married pregnant women in Abay Chomen district in April, 2014 using a standard WHO multi-country study questionnaire. Two hundred eighty two randomly selected pregnant women aged 15-49 years participated in the study. Logistic regression and multivariate analysis were employed. The prevalence of intimate partner violence during recent pregnancy was 44.5% (95% CI, 32.6, 56.4). More than half 157 (55.5%) experienced all three forms of intimate partner violence during recent pregnancy. The joint occurrence of intimate partner physical and psychological violence during recent pregnancy as well as joint occurrence of intimate partner physical and sexual violence was 160 (56.5%). Pregnant women who were ever lived with their partner's family were 46% less likely to experience recent intimate partner violence. Dowry payment decreases intimate partner violence during recent pregnancy (AOR 0.09, 95% CI 0.04, 0.2) and pregnant women who didn't undergo marriage ceremony during their marriage were 79% are less likely to experience violence (AOR 0.21, 95% CI 0.1, 0.44). Nearly half of interviewed pregnant women experienced intimate partner violence during pregnancy implying the prevalence of such practice in the study site. To that end, increasing community awareness about the consequences of the practice could be important. Moreover, as health extension workers works closely with households, they could be crucial players to increase community awareness about intimate partner violence on

  5. The Carbon Cycle at the Nile Headwaters

    NASA Astrophysics Data System (ADS)

    Jones, Michael; Saunders, Matthew

    2014-05-01

    The carbon cycle at the Nile headwaters M B Jones, School of Natural Sciences, Trinity College, University of Dublin, Dublin 2, Ireland M Saunders, Environmental and Biochemical Sciences Group, The James Hutton Institute, Aberdeen, Scotland River systems play an integral role in the global carbon cycle by connecting the terrestrial biosphere, the atmosphere and the oceans. Extensive wetland systems, such as those found in the Amazon region, have been shown to export significant amounts of carbon to river waters as dissolved carbon dioxide (CO2) that can be transported and emitted hundreds of km downstream. The assessment of both regional and global carbon budgets could therefore be improved by quantifying these lateral carbon fluxes, especially from highly productive temporarily or permanently flooded areas where substantial CO2 evasion from inland waters can occur. The Nile is the longest river in the world and the headwaters are located in the extensive Papyrus dominated wetlands in central Africa that are associated with Lake Victoria. From its source the White Nile flows northwards through wetlands in Uganda and Sudan before it joins the Blue Nile. Papyrus wetlands have been shown to be some of the most productive global ecosystems, with recorded rates of aerial net primary productivity of up to 3.09 kg C m-2 yr-1. In addition, where anaerobic conditions occur they also accumulate large amounts of carbon in the form of peat, and under these circumstances they represent a significant carbon sink. However, as water moves through these wetlands and is exchanged with surrounding rivers and lakes significant quantities of dissolved organic and inorganic carbon as well as suspended particulate organic matter are exported, which are either released further downstream by degassing, decomposition or deposition. Information on such losses from these wetland ecosystems is extremely sparse but in order to better constrain ecosystem scale carbon dynamics more accurate

  6. Nile behaviour and Late Palaeolithic humans in Upper Egypt during the Late Pleistocene

    NASA Astrophysics Data System (ADS)

    Vermeersch, Pierre M.; Van Neer, Wim

    2015-12-01

    The reconstruction of the environment and the human population history of the Nile Valley during the Late Pleistocene have received a lot of attention in the literature thus far. There seems to be a consensus that during MIS2 extreme dry conditions prevailed over north-eastern Africa, which was apparently not occupied by humans. The Nile Valley seems to be an exception; numerous field data have been collected suggesting an important population density in Upper Egypt during MIS2. The occupation remains are often stratified in, or at least related to, aeolian and Nile deposits at some elevation above the present-day floodplain. They are rich in lithics and animal bones, mainly fish, illustrating the exploitation of the Nile Valley by the Late Palaeolithic inhabitants. The fluvial processes active during that period have traditionally been interpreted as a continuously rising highly braided river. In this paper we summarize the evidence thus far available for the Late Pleistocene on the population densities in the Nile Valley, and on the models of Nilotic behaviour. In the discussion we include data on the environmental conditions in Eastern Africa, on the aeolian processes in the Western Desert of Egypt derived from satellite images, 14C and OSL dates, in order to formulate a new model that explains the observed high remnants of aeolian and Nilotic deposits and the related Late Palaeolithic sites. This model hypothesizes that, during the Late Pleistocene, and especially the LGM, dunes from the Western Desert invaded the Nile Valley at several places in Upper Egypt. The much reduced activity of the White Nile and the Blue Nile was unable to evacuate incoming aeolian sand and, as a consequence, several dams were created in the Upper Egyptian Nile Valley. Behind such dams the created lakes offered ideal conditions for human subsistence. This model explains the occurrence of Late Palaeolithic hunter-fisher-gatherers in a very arid environment with very low Nile flows

  7. Shifting sediment sources in the world's longest river: A strontium isotope record for the Holocene Nile

    NASA Astrophysics Data System (ADS)

    Woodward, Jamie; Macklin, Mark; Fielding, Laura; Millar, Ian; Spencer, Neal; Welsby, Derek; Williams, Martin

    2015-12-01

    We have reconstructed long-term shifts in catchment sediment sources by analysing, for the first time, the strontium (Sr) and neodymium (Nd) isotope composition of dated floodplain deposits in the Desert Nile. The sediment load of the Nile has been dominated by material from the Ethiopian Highlands for much of the Holocene, but tributary wadis and aeolian sediments in Sudan and Egypt have also made major contributions to valley floor sedimentation. The importance of these sources has shifted dramatically in response to global climate changes. During the African Humid Period, before c. 4.5 ka, when stronger boreal summer insolation produced much higher rainfall across North Africa, the Nile floodplain in northern Sudan shows a tributary wadi input of 40-50%. Thousands of tributary wadis were active at this time along the full length of the Saharan Nile in Egypt and Sudan. As the climate became drier after 4.5 ka, the valley floor shows an abrupt fall in wadi inputs and a stronger Blue Nile/Atbara contribution. In the arid New Kingdom and later periods, in palaeochannel fills on the margins of the valley floor, aeolian sediments replace wadi inputs as the most important secondary contributor to floodplain sedimentation. Our sediment source data do not show a measurable contribution from the White Nile to the floodplain deposits of northern Sudan over the last 8500 years. This can be explained by the distinctive hydrology and sediment delivery dynamics of the upper Nile basin. High strontium isotope ratios observed in delta and offshore records - that were previously ascribed to a stronger White Nile input during the African Humid Period - may have to be at least partly reassessed. Our floodplain Sr records also have major implications for bioarchaeologists who carry out Sr isotope-based investigations of ancient human remains in the Nile Valley because the isotopic signature of Nile floodplain deposits has shifted significantly over time.

  8. Synthesis and optical properties of pyrrolidinyl peptide nucleic acid carrying a clicked Nile red label.

    PubMed

    Yotapan, Nattawut; Charoenpakdee, Chayan; Wathanathavorn, Pawinee; Ditmangklo, Boonsong; Wagenknecht, Hans-Achim; Vilaivan, Tirayut

    2014-01-01

    DNA or its analogues with an environment-sensitive fluorescent label are potentially useful as a probe for studying the structure and dynamics of nucleic acids. In this work, pyrrolidinyl peptide nucleic acid (acpcPNA) was labeled at its backbone with Nile red, a solvatochromic benzophenoxazine dye, by means of click chemistry. The optical properties of the Nile red-labeled acpcPNA were investigated by UV-vis and fluorescence spectroscopy in the absence and in the presence of DNA. In contrast to the usual quenching observed in Nile red-labeled DNA, the hybridization with DNA resulted in blue shifting and an enhanced fluorescence regardless of the neighboring bases. More pronounced blue shifts and fluorescence enhancements were observed when the DNA target carried a base insertion in close proximity to the Nile red label. The results indicate that the Nile red label is located in a more hydrophobic environment in acpcPNA-DNA duplexes than in the single-stranded acpcPNA. The different fluorescence properties of the acpcPNA hybrids of complementary DNA and DNA carrying a base insertion are suggestive of different interactions between the Nile red label and the duplexes.

  9. Synthesis and optical properties of pyrrolidinyl peptide nucleic acid carrying a clicked Nile red label

    PubMed Central

    Yotapan, Nattawut; Charoenpakdee, Chayan; Wathanathavorn, Pawinee; Ditmangklo, Boonsong

    2014-01-01

    Summary DNA or its analogues with an environment-sensitive fluorescent label are potentially useful as a probe for studying the structure and dynamics of nucleic acids. In this work, pyrrolidinyl peptide nucleic acid (acpcPNA) was labeled at its backbone with Nile red, a solvatochromic benzophenoxazine dye, by means of click chemistry. The optical properties of the Nile red-labeled acpcPNA were investigated by UV–vis and fluorescence spectroscopy in the absence and in the presence of DNA. In contrast to the usual quenching observed in Nile red-labeled DNA, the hybridization with DNA resulted in blue shifting and an enhanced fluorescence regardless of the neighboring bases. More pronounced blue shifts and fluorescence enhancements were observed when the DNA target carried a base insertion in close proximity to the Nile red label. The results indicate that the Nile red label is located in a more hydrophobic environment in acpcPNA–DNA duplexes than in the single-stranded acpcPNA. The different fluorescence properties of the acpcPNA hybrids of complementary DNA and DNA carrying a base insertion are suggestive of different interactions between the Nile red label and the duplexes. PMID:25246975

  10. Mental Status after West Nile Virus Infection

    PubMed Central

    Sadek, Joseph; Pergam, Steven; Echevarria, Leonor A.; Davis, Larry E.; Goade, Diane; Harnar, Joanne; Nofchissey, Robert A.; Sewel, C. Mack; Ettestad, Paul

    2006-01-01

    Mental status after acute West Nile virus infection has not been examined objectively. We compared Telephone Interview for Cognitive Status scores of 116 patients with West Nile fever or West Nile neuroinvasive disease. Mental status was poorer and cognitive complaints more frequent with West Nile neuroinvasive disease (p = 0.005). PMID:16965710

  11. Environmental color affects Nile tilapia reproduction.

    PubMed

    Volpato, G L; Duarte, C R A; Luchiari, A C

    2004-04-01

    We investigated the effects of environmental color on the reproductive behavior of Nile tilapia, Oreochromis niloticus. Two environmental colors were tested by covering the aquarium (60 x 60 x 40 cm) with white (12 groups) or blue (13 groups) cellophane and observing reproductive behavior in groups of 2 males (10.27 +/- 0.45 cm) and 3 females (10.78 +/- 0.45 cm) each. After assignment to the respective environmental color (similar luminosity = 100 to 120 Lux), the animals were observed until reproduction (identified by eggs in the female's mouth) or up to 10 days after the first nest building. Photoperiod was from 6:00 h to 18:00 h every day. Food was offered in excess once a day and water quality was similar among aquaria. Daily observations were made at 8:00, 11:00, 14:00 and 17:00 h regarding: a) latency to the first nest, b) number of nests, c) gravel weight removed (the male excavates the nest in the bottom of the aquarium), d) nest area, and e) mouthbrooding incubation (indication of reproduction). The proportion of reproducing fish was significantly higher (6 of 13) in the group exposed to the blue color compared the group exposed to the white color (1 of 12; Goodman's test of proportions). Moreover, males under blue light removed significantly larger masses of gravel (blue = 310.70 +/- 343.50 g > white = 130.38 +/- 102.70 g; P = 0.01) and constructed wider nests (blue = 207.93 +/- 207.80 cm(2) > white = 97.68 +/- 70.64 cm(2); P = 0.03) than the control (white). The other parameters did not differ significantly between light conditions. We concluded that reproduction in the presence of blue light was more frequent and intense than in the presence of white light.

  12. Major and trace element distribution in soil and sediments from the Egyptian central Nile Valley

    NASA Astrophysics Data System (ADS)

    Badawy, W. M.; Ghanim, E. H.; Duliu, O. G.; El Samman, H.; Frontasyeva, M. V.

    2017-07-01

    The distributions of 32 major and trace elements in 72 surface soil and sediment samples collected from the Asyut to Cairo Nile river section were determined by epithermal neutron activation analysis and compared with corresponding data for the Upper Continental Crust, North American Shale Composite, Average Soil and Average Sediment as well as suspended sediments from Congo and Upper Niger Rivers, in order to establish to which extent the Nile sedimentary material can be related to similar material all over the world as well as to local geology. Their relative distributions indicate the presence of detrital material of igneous origin, most probably resulting from weathering of the Ethiopian Highlands and transported by the Blue Nile, the Nile main tributary. The distributions of nickel, zinc, and arsenic contents suggest that the lower part of the Nile and its surroundings including the Nile Delta is not seriously polluted with heavy metals, so that, in spite of a human activity, which lasted four millennia, the Nile River continues to be less affected by any anthropogenic contamination.

  13. Hydroclimate variability in the Nile River Basin during the past 28,000 years

    NASA Astrophysics Data System (ADS)

    Castañeda, Isla S.; Schouten, Stefan; Pätzold, Jürgen; Lucassen, Friedrich; Kasemann, Simone; Kuhlmann, Holger; Schefuß, Enno

    2016-03-01

    It has long been known that extreme changes in North African hydroclimate occurred during the late Pleistocene yet many discrepancies exist between sites regarding the timing, duration and abruptness of events such as Heinrich Stadial (HS) 1 and the African Humid Period (AHP). The hydroclimate history of the Nile River is of particular interest due to its lengthy human occupation history yet there are presently few continuous archives from the Nile River corridor, and pre-Holocene studies are rare. Here we present new organic and inorganic geochemical records of Nile Basin hydroclimate from an eastern Mediterranean (EM) Sea sediment core spanning the past 28 ka BP. Our multi-proxy records reflect the fluctuating inputs of Blue Nile versus White Nile material to the EM Sea in response to gradual changes in local insolation and also capture abrupt hydroclimate events driven by remote climate forcings, such as HS1. We find strong evidence for extreme aridity within the Nile Basin evolving in two distinct phases during HS1, from 17.5 to 16 ka BP and from 16 to 14.5 ka BP, whereas peak wet conditions during the AHP are observed from 9 to 7 ka BP. We find that zonal movements of the Congo Air Boundary (CAB), and associated shifts in the dominant moisture source (Atlantic versus Indian Ocean moisture) to the Nile Basin, likely contributed to abrupt hydroclimate variability in northern East Africa during HS1 and the AHP as well as to non-linear behavior of hydroclimate proxies. We note that different proxies show variable gradual and abrupt responses to individual hydroclimate events, and thus might have different inherent sensitivities, which may be a factor contributing to the controversy surrounding the abruptness of past events such as the AHP. During the Late Pleistocene the Nile Basin experienced extreme hydroclimate fluctuations, which presumably impacted Paleolithic cultures residing along the Nile corridor.

  14. Solar Forcings on Nile and Earthquakes

    NASA Astrophysics Data System (ADS)

    Al-Shehri, Saad Mohammed; Sabbah, Ismail; Yousef, Shahinaz Moustafa; Amin, Magdy Y.

    2013-03-01

    Nile and earthquake periodicities are examined in the light of solar and geomagnetic periodicities in order to uncover the role of the sun in initiating such terrestrial phenomena. The Nile periodicities under considerations covers the period 622-1420 AD. 1749- 1800 and 1870-1945 and are taken from an earlier paper by Yousef and El-Rae (1995). It is found that 11 yr and 21 yr solar periodicities affected the White Nile originating from the Equatorial plateau. On the other hand the Blue Nile arising mainly from Lake Tana in Ethiopia was affected mostly by the 3.3 yr, 2.9 yr, 2.7 yr, and the 2.52 yr periodicities. Such short periodicities are also present in cosmic rays. This is fairly true as during weak solar cycles series at the bottom of the 80-120 year Solar Wolf-Gleissberg Cycles, the level of the second to last of the weak cycles rise and fall coherently with full solar cycles with a correlation coefficient of about 0.9. Rain over Ethiopia is affected by the Monsoon precipitation which is related to the quasi biennial oscillations QBO of the equatorial zonal wind between the easterlies and the westerlies in the tropical stratosphere with a mean period of 29 months. We propose that the QBO are stimulated by the 2.52-2.48 yr solar periodicities. The 2.52 and 2.48 yr periodicity is strong in odd solar cycles 21 and 23. Generally speaking, it looks that different solar periodicities are space-time dependant and that they affect different regimes of terrestrial responses. In the case of earthquakes, we think that they are related to geomagnetic storms initiated by solar stimuli. Several solar periodicities are found in earthquakes. We postulate that electric currents in the ring current and in the ionosphere induce surface as well as deep electric currents in the magma thus produce motion and disturbances of the plates and the magma leading to earthquakes and volcanoes.

  15. Space Radar Image of Nile River Delta, Egypt

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This spaceborne radar image shows the area just north of the city of Cairo, Egypt, where the Nile River splits into two main branches. The Rosetta Branch is the curving dark line in the center of the image and the Damietta Branch is the curving dark line in the lower right of the image. The light blue area on the right half of the image is a portion of the Nile River Delta. The thinner, straighter lines and the small network of gold lines are irrigation canals. There are more than 10,000 kilometers of canals throughout the Nile Delta. A transition zone of irrigated fields is shown in blue and yellow between the irrigated delta and the surrounding desert. The desert is the dark blue area on the left side of the image lacking the pattern of irrigated fields. This image was acquired by the Spaceborne Imaging Radar-C/X-band Synthetic Aperture Radar (SIR-C/X-SAR) on October 4, 1994, onboardthe space shuttle Endeavour. The image is 75 kilometers by 60 kilometers (46 miles by 37 miles) and is centered at 30.2 degreesnorth latitude, 31.1 degrees east longitude. North is toward the upper right. The colors are assigned to different radar frequencies and polarizations as follows: red is L-band, horizontally transmitted and received; green is C-band, horizontally transmitted and received; and blue is the ratio of C-band and L-band, horizontally transmitted and received. SIR-C/X-SAR, a joint mission of the German, Italian and United States space agencies, is part of NASA's Mission to PlanetEarth program.

  16. Monitoring the Spread of West Nile Virus with Satellite Data

    NASA Technical Reports Server (NTRS)

    2002-01-01

    A NASA-funded study uses temperature and vegetation data from satellites to help track and predict where West Nile virus is spreading in North America. Scientists and public health officials hope one day to use near real-time maps to focus resources and stave off the disease more efficiently. This image is a composite of land surface temperatures (LST) recorded between 1997 and 2000 and was used to help monitor and predict the spread of West Nile virus in the United States. In the color figure above, the mean land surface temperatures are in red; annual amplitude-or the difference between low and high annual temperatures-is in blue; and annual phase-or the timing of annual temperature peaks-appears in green. Brighter colors mean higher values. The major north-south temperature difference (dull red in the upper part of the image to bright red in the lower part) is considerably affected by the Rockies in the west and to a much lesser extent by the Appalachians in the east. The brighter blue in the upper part of the image indicates the big difference between highest and lowest temperatures during the course of a year at higher latitudes. There is less variation in the timing of the annual peak of land surface temperatures, which occurs earlier in the south than in the north. Black dots superimposed on this image are the locations (county geo-centers) where birds infected with West Nile virus were reported between January and October 2001. Scientists working with the International Research Partnership for Infectious Diseases (INTREPID) program based at NASA are using such imagery to define and predict the conditions where mosquitoes transmit West Nile virus in the U.S. The conclusion reached about the importance of any single variable depends both upon its value and context. A temperature of 30o Celsius (86o Fahrenheit) might be fatal for a mosquito at low humidity but survivable at higher humidities. The work done here on West Nile virus and other diseases shows very

  17. Monitoring the Spread of West Nile Virus with Satellite Data

    NASA Technical Reports Server (NTRS)

    2002-01-01

    A NASA-funded study uses temperature and vegetation data from satellites to help track and predict where West Nile virus is spreading in North America. Scientists and public health officials hope one day to use near real-time maps to focus resources and stave off the disease more efficiently. This image is a composite of land surface temperatures (LST) recorded between 1997 and 2000 and was used to help monitor and predict the spread of West Nile virus in the United States. In the color figure above, the mean land surface temperatures are in red; annual amplitude-or the difference between low and high annual temperatures-is in blue; and annual phase-or the timing of annual temperature peaks-appears in green. Brighter colors mean higher values. The major north-south temperature difference (dull red in the upper part of the image to bright red in the lower part) is considerably affected by the Rockies in the west and to a much lesser extent by the Appalachians in the east. The brighter blue in the upper part of the image indicates the big difference between highest and lowest temperatures during the course of a year at higher latitudes. There is less variation in the timing of the annual peak of land surface temperatures, which occurs earlier in the south than in the north. Black dots superimposed on this image are the locations (county geo-centers) where birds infected with West Nile virus were reported between January and October 2001. Scientists working with the International Research Partnership for Infectious Diseases (INTREPID) program based at NASA are using such imagery to define and predict the conditions where mosquitoes transmit West Nile virus in the U.S. The conclusion reached about the importance of any single variable depends both upon its value and context. A temperature of 30o Celsius (86o Fahrenheit) might be fatal for a mosquito at low humidity but survivable at higher humidities. The work done here on West Nile virus and other diseases shows very

  18. Natural equilibria and anthropic effects on sediment transport in big river systems: The Nile case

    NASA Astrophysics Data System (ADS)

    Garzanti, Eduardo; Andò, Sergio; Padoan, Marta; Vezzoli, Giovanni; Villa, Igor

    2014-05-01

    The Nile River flows for ~ 6700 km, from Burundi and Rwanda highlands south of the Equator to the Mediterranean Sea at northern subtropical latitudes. It is thus the longest natural laboratory on Earth, a unique setting in which we are carrying out a continuing research project to investigate changes in sediment composition associated with a variety of chemical and physical processes, including weathering in equatorial climate and hydraulic sorting during transport and deposition. Petrographic, mineralogical, chemical, and isotopic fingerprints of sand and mud have been monitored along all Nile branches, from the Kagera and White Nile draining Archean, Paleoproterozoic and Mesoproterozoic basements uplifted along the western branch of the East African rift, to the Blue Nile and Atbara Rivers sourced in Ethiopian volcanic highlands made of Oligocene basalt. Downstream of the Atbara confluence, the Nile receives no significant tributary water and hardly any rainfall across the Sahara. After construction of the Aswan High Dam in 1964, the Nile ceased to be an active conveyor-belt in Egypt, where the mighty river has been tamed to a water canal; transported sediments are thus chiefly reworked from older bed and levee deposits, with minor contributions from widyan sourced in the Red Sea Hills and wind-blown desert sand and dust. Extensive dam construction has determined a dramatic sediment deficit at the mouth, where deltaic cusps are undergoing ravaging erosion. Nile delta sediments are thus recycled under the effect of dominant waves from the northwest, the longest Mediterranean fetch direction. Nile sands, progressively enriched in more stable minerals such as quartz and amphiboles relative to volcanic rock fragments and pyroxene, thus undergo multistep transport by E- and NE-directed longshore currents all along the coast of Egypt and Palestine, and are carried as far as Akko Bay in northern Israel. Nile mud reaches the Iskenderun Gulf in southern Turkey. A full

  19. West Nile Virus

    PubMed Central

    Rossi, Shannan L.; Ross, Ted M.; Evans, Jared D.

    2010-01-01

    Overview Since its isolation in Uganda in 1937, West Nile virus (WNV) has been responsible for thousands of cases of morbidity and mortality in birds, horses, and humans. Historically, epidemics were localized to Europe, Africa, the Middle East, and parts of Asia, and primarily caused a mild febrile illness in humans. However, in the late 1990’s, the virus became more virulent and expanded its geographical range to North America. In humans, the clinical presentation ranges from asymptomatic (approximately 80% of infections) to encephalitis/paralysis and death (less than 1% of infections). There is no FDA-licensed vaccine for human use, and the only recommended treatment is supportive care. Individuals that survive infection often have a long recovery period. This article will review the current literature summarizing the molecular virology, epidemiology, clinical manifestations, pathogenesis, diagnosis, treatment, immunology, and protective measures against WNV and WNV infections in humans. PMID:20513541

  20. Mutually beneficial and sustainable management of Ethiopian and Egyptian dams in the Nile Basin

    NASA Astrophysics Data System (ADS)

    Habteyes, Befekadu G.; Hasseen El-bardisy, Harb A. E.; Amer, Saud A.; Schneider, Verne R.; Ward, Frank A.

    2015-10-01

    Ongoing pressures from population growth, recurrent drought, climate, urbanization and industrialization in the Nile Basin raise the importance of finding viable measures to adapt to these stresses. Four tributaries of the Eastern Nile Basin contribute to supplies: the Blue Nile (56%), White Nile-Albert (14%), Atbara (15%) and Sobat (15%). Despite much peer reviewed work addressing conflicts on the Nile, none to date has quantitatively examined opportunities for discovering benefit sharing measures that could protect negative impacts on downstream water users resulting from new upstream water storage developments. The contribution of this paper is to examine the potential for mutually beneficial and sustainable benefit sharing measures from the development and operation of the Grand Ethiopian Renaissance Dam while protecting baseline flows to the downstream countries including flows into the Egyptian High Aswan Dam. An integrated approach is formulated to bring the hydrology, economics and institutions of the region into a unified framework for policy analysis. A dynamic optimization model is developed and applied to identify the opportunities for Pareto Improving measures to operate these two dams for the four Eastern Nile Basin countries: Ethiopia, South Sudan, Sudan, and Egypt. Results indicate a possibility for one country to be better off (Ethiopia) and no country to be worse off from a managed operation of these two storage facilities. Still, despite the optimism of our results, considerable diplomatic negotiation among the four riparians will be required to turn potential gains into actual welfare improvements.

  1. The modern Nile sediment system: Processes and products

    NASA Astrophysics Data System (ADS)

    Garzanti, Eduardo; Andò, Sergio; Padoan, Marta; Vezzoli, Giovanni; El Kammar, Ahmed

    2015-12-01

    We trace compositional changes of Nile sediments for 7400 km, from their sources in equatorial rift highlands of Burundi and Rwanda to their sink in the Mediterranean Sea. All chemical and physical controls on sediment petrography, mineralogy and geochemistry, including weathering, grain-size, hydraulic sorting, mechanical breakdown, anthropic impact, mixing and recycling are investigated in detail. The Nile course is controlled along its entire length by the East African-Red Sea Rift. In this anorogenic setting, detritus is derived in various proportions from volcanic fields associated with tectonic extension (Anorogenic Volcanic provenance) and from igneous, metamorphic and sedimentary rocks uplifted on the rift shoulders or exposed on the craton (Continental Block provenance). The entire spectrum of such detrital signatures is displayed in the Nile catchment. Volcaniclastic Atbara sand is generated by focused erosion of the Ethiopian basaltic plateau in semiarid climate, whereas quartzose White Nile sand reflects low erosion rates, extensive weathering and sediment trapping in lakes and swamps at equatorial to subequatorial latitudes. In the main Nile, as in its main tributary the Blue Nile, suspended load is volcaniclastic, whereas feldspatho-quartzose bedload is derived largely from basement sources, with fine to medium-grained eolian sand added along the lower course. Mixing of detrital populations with different provenance and grain size is reflected in diverse violations of settling-equivalence relationships in fluvial and deltaic sediments. Sediment delivery from Sudan has been cut off after closure of the Aswan High Dam and accelerated erosion of deltaic cusps is leading to local formation of placer lags dominated by ultradense Fe-Ti-Cr oxides, but mineralogical changes caused by man's radical modification of fluvial regimes have been minor so far. In beaches of Sinai, Gaza and Israel, the Nile volcaniclastic trace gets progressively diluted by quartzose

  2. Nile River, Lake Nasser, Aswan Dam, Egypt

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Egypt's High Aswan Dam on the Nile River at the first cataracts, Nile River, (24.0N, 33.0E) was completed in 1971 to provide cheap hydroelectric power and to regulate the historically uneven flow of the Nile River. The contrast between the largely base rock desert east of the Nile versus the sand covered desert west of the river and the ancient irrigated floodplain downstream from the damsite is clearly shown.

  3. Nile River, Lake Nasser, Aswan Dam, Egypt

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Egypt's High Aswan Dam on the Nile River at the first cataracts, Nile River, (24.0N, 33.0E) was completed in 1971 to provide cheap hydroelectric power and to regulate the historically uneven flow of the Nile River. The contrast between the largely base rock desert east of the Nile versus the sand covered desert west of the river and the ancient irrigated floodplain downstream from the damsite is clearly shown.

  4. Nile River, Lake Nasser, Aswan Dam, Egypt

    NASA Image and Video Library

    1991-08-11

    Egypt's High Aswan Dam on the Nile River at the first cataracts, Nile River, (24.0N, 33.0E) was completed in 1971 to provide cheap hydroelectric power and to regulate the historically uneven flow of the Nile River. The contrast between the largely base rock desert east of the Nile versus the sand covered desert west of the river and the ancient irrigated floodplain downstream from the damsite is clearly shown.

  5. Control Over the Nile: Implications across Nations

    DTIC Science & Technology

    2010-06-01

    Declaration...................................................................50 3. The Hydro-Meteorological Survey of the Equatorial Lakes ( HYDROMET ...Eastern Nile Subsidiary Action Program HYDROMET Hydro-Meteorological Survey of the Equatorial Lakes IMF International Monetary Fund NBI Nile...The Hydro-Meteorological Survey of the Equatorial Lakes ( HYDROMET ) Led by Egypt, the Nile basin countries of Kenya, Uganda, Tanzania, and Sudan

  6. Antibody response of five bird species after vaccination with a killed West Nile virus vaccine.

    PubMed

    Okeson, Danelle M; Llizo, Shirley Yeo; Miller, Christine L; Glaser, Amy L

    2007-06-01

    West Nile virus has been associated with numerous bird mortalities in the United States since 1999. Five avian species at three zoological parks were selected to assess the antibody response to vaccination for West Nile virus: black-footed penguins (Spheniscus demersus), little blue penguins (Eudyptula minor), American flamingos (Phoenicopterus ruber), Chilean flamingos (Phoenicopterus chilensis), and Attwater's prairie chickens (Tympanuchus cupido attwateri). All birds were vaccinated intramuscularly at least twice with a commercially available inactivated whole virus vaccine (Innovator). Significant differences in antibody titer over time were detected for black-footed penguins and both flamingo species.

  7. [West Nile virus infection].

    PubMed

    Pérez Ruiz, Mercedes; Gámez, Sara Sanbonmatsu; Clavero, Miguel Angel Jiménez

    2011-12-01

    West Nile virus (WNV) is an arbovirus usually transmitted by mosquitoes. The main reservoirs are birds, although the virus may infect several vertebrate species, such as horses and humans. Up to 80% of human infections are asymptomatic. The most frequent clinical presentation is febrile illness, and neuroinvasive disease can occur in less than 1% of cases. Spain is considered a high-risk area for the emergence of WNV due to its climate and the passage of migratory birds from Africa (where the virus is endemic). These birds nest surrounding wetlands where populations of possible vectors for the virus are abundant. Diagnosis of human neurological infections can be made by detection of IgM in serum and/or cerebrospinal fluid samples, demonstration of a four-fold increase in IgG antibodies between acute-phase and convalescent-phase serum samples, or by detection of viral genome by reverse transcription-polymerase chain reaction (especially useful in transplant recipients). Since WNV is a biosafety level 3 agent, techniques that involve cell culture are restricted to laboratories with this level of biosafety, such as reference laboratories. The National Program for the Surveillance of WNV Encephalitis allows the detection of virus circulation among birds and vectors in areas especially favorable for the virus, such as wetlands, and provides information for evaluation of the risk of disease in horses and humans.

  8. [Maternity blues].

    PubMed

    Gonidakis, F

    2007-04-01

    Maternity blues is a transient change of mood that occurs mainly between the 1st and 10th day of puerpartum and is characterized by bursts of tears, mild depressive mood, anxiety and liability of mood. The frequency of maternity blues varies in different studies form 4% to 80%. A number of biological and psychosocial parameters have been studied in order to determine their correlation with maternity blues. The most well studied biological parameters are progesterone and cortizol although their relation with maternity blues has not yet been clearly defined. Stress and the emotional state of the woman during pregnancy as well as history of mood disorders or maternity blues in a previous birth are the psychosocial parameters that are more likely to correlate with the occurrence of maternity blues. Most of the authors suggest that information on maternity blues and reassurance of the woman are the best way to deal with maternity blues both on preventive and therapeutical basis.

  9. The White Nile sedimentary system

    NASA Astrophysics Data System (ADS)

    Garzanti, Eduardo; Andò, Sergio; Padoan, Marta; Resentini, Alberto; Vezzoli, Giovanni; Villa, Igor

    2014-05-01

    The Nile River flows for ~6700 km from south of the Equator to finally reach the Mediterranean Sea at northern subtropical latitudes (Woodward et al. 2007). This is the longest sedimentological laboratory on Earth, a unique setting in which we are investigating changes in sediment composition associated with diverse chemical and physical processes, including weathering and hydraulic sorting. The present study focuses on the southern branch of the Nile across 20° of latitude, from hyperhumid Burundi and Rwanda highlands in central Africa to Khartoum, the capital city of Sudan at the southern edge of the Sahara. Our study of the Kagera basin emphasizes the importance of weathering in soils at the source rather than during stepwise transport, and shows that the transformation of parent rocks into quartzose sand may be completed in one sedimentary cycle (Garzanti et al. 2013a). Micas and heavy minerals, less effectively diluted by recycling than main framework components, offer the best key to identify the original source-rock imprint. The different behaviour of chemical indices such as the CIA (a truer indicator of weathering) and the WIP (markedly affected by quartz dilution) helps us to distinguish strongly weathered first-cycle versus polycyclic quartz sands (Garzanti et al. 2013b). Because sediment is efficiently trapped in East African Rift lakes, the composition of Nile sediments changes repeatedly northwards across Uganda. Downstream of both Lake Kyoga and Lake Albert, quartzose sands are progressively enriched in metamorphiclastic detritus supplied from tributaries draining amphibolite-facies basements. The evolution of White Nile sediments across South Sudan, a scarcely accessible region that suffered decades of civil war, was inferred from the available information (Shukri 1950), integrated by original petrographic, heavy-mineral and geochemical data (Padoan et al. 2011). Mineralogical and isotopic signatures of Bahr-el-Jebel and Sobat sediments, derived

  10. Blue Note

    ScienceCinema

    Murray Gibson

    2016-07-12

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  11. Blue Note

    SciTech Connect

    Murray Gibson

    2007-04-27

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  12. The monoamine oxidase inhibition properties of selected structural analogues of methylene blue.

    PubMed

    Delport, Anzelle; Harvey, Brian H; Petzer, Anél; Petzer, Jacobus P

    2017-06-15

    The thionine dye, methylene blue (MB), is a potent inhibitor of monoamine oxidase (MAO) A, a property that may, at least in part, mediate its antidepressant effects in humans and animals. The central inhibition of MAO-A by MB has also been linked to serotonin toxicity (ST) which may arise when MB is used in combination with serotonergic drugs. Structural analogues and the principal metabolite of MB, azure B, have also been reported to inhibit the MAO enzymes, with all compounds exhibiting specificity for the MAO-A isoform. To expand on the structure-activity relationships (SARs) of MAO inhibition by MB analogues, the present study investigates the human MAO inhibition properties of five MB analogues: neutral red, Nile blue, new methylene blue, cresyl violet and 1,9-dimethyl methylene blue. Similar to MB, these analogues also are specific MAO-A inhibitors with cresyl violet (IC50=0.0037μM), Nile blue (IC50=0.0077μM) and 1,9-dimethyl methylene blue (IC50=0.018μM) exhibiting higher potency inhibition compared to MB (IC50=0.07μM). Nile blue also represents a potent MAO-B inhibitor with an IC50 value of 0.012μM. From the results it may be concluded that non-thionine MB analogues (e.g. cresyl violet and Nile blue) also may exhibit potent MAO inhibition, a property which should be considered when using these compounds in pharmacological studies. Benzophenoxazines such as cresyl violet and Nile blue are, similar to phenothiazines (e.g. MB), representative of high potency MAO-A inhibitors with a potential risk of ST. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Socioeconomic dynamics of water quality in the Egyptian Nile

    NASA Astrophysics Data System (ADS)

    Malik, Maheen; Nisar, Zainab; Karakatsanis, Georgios

    2016-04-01

    The Nile River remains the most important source of freshwater for Egypt as it accounts for nearly all of the country's drinking and irrigation water. About 95% of the total population is accounted to live along the Banks of the Nile(1). Therefore, water quality deterioration in addition to general natural scarcity of water in the region(2) is the main driver for carrying out this study. What further aggravates this issue is the water conflict in the Blue Nile region. The study evaluates different water quality parameters and their concentrations in the Egyptian Nile; further assessing the temporal dynamics of water quality in the area with (a) the Environmental Kuznets Curve (EKC)(3) and (b) the Jevons Paradox (JP)(4) in order to identify water quality improvements or degradations using selected socioeconomic variables(5). For this purpose various environmental indicators including BOD, COD, DO, Phosphorus and TDS were plotted against different economic variables including Population, Gross Domestic Product (GDP), Annual Fresh Water Withdrawal and Improved Water Source. Mathematically, this was expressed by 2nd and 3rd degree polynomial regressions generating the EKC and JP respectively. The basic goal of the regression analysis is to model and highlight the dynamic trend of water quality indicators in relation to their established permissible limits, which will allow the identification of optimal future water quality policies. The results clearly indicate that the dependency of water quality indicators on socioeconomic variables differs for every indicator; while COD was above the permissible limits in all the cases despite of its decreasing trend in each case, BOD and phosphate signified increasing concentrations for the future, if they continue to follow the present trend. This could be an indication of rebound effect explained by the Jevons Paradox i.e. water quality deterioration after its improvement, either due to increase of population or intensification

  14. Vertical transmission of microcystins to Nile crocodile (Crocodylus niloticus) eggs.

    PubMed

    Singo, Alukhethi; Myburgh, Jan G; Laver, Peter N; Venter, Elizabeth A; Ferreira, Gezina C H; Rösemann, Gertruida M; Botha, Christo J

    2017-08-01

    Cyanobacteria or blue green algae are known for their extensive and highly visible blooms in eutrophic, stagnant freshwater bodies. Climate change and global warming have also contributed to a rise in toxic cyanobacterial blooms. One of the most important cyanobacteria is Microcystis aeruginosa, which can synthesize various microcystins that can affect the health of terrestrial and aquatic animals. Commercial Nile crocodile (Crocodylus niloticus) farming in South Africa is based on keeping breeders (adult males and females) in big dams on farms (captive-bred approach). Unfortunately, cyanobacterial blooms in the breeder dams are a concern to farm owners, managers and veterinarians. The main objectives of this research project were to determine if microcystins were present in the contents of crocodile eggs and the liver and yolk of dead hatchlings, and to determine if the reduced hatchability on commercial farms might be caused by these toxins. Furthermore, the concentration of microcystins in the breeder dam was monitored on a monthly basis spanning the ovulation and egg laying period. During the hatching season microcystin concentrations in unfertilised eggs, egg shell membranes and in the yolk and liver of dead hatchlings were determined using liquid chromatography-high resolution mass spectrometry (LC-HRMS). Microcystins were detected in Nile crocodile egg and hatchling samples. Microcystin (MC-LR, MC-RR, MC-YR) concentrations in the crocodile egg and hatchling samples collected from clutches with a good hatching rate (≥90%) ranged between 0 and 1.76 ng g(-1), with the highest concentration in the egg shell membranes. Microcystin concentrations in samples collected from clutches with a bad hatching rate (≤10%) ranged from 0 - 1.63 ng g(-1) with the highest concentration detected in the hatchling yolk. However, the concentrations were probably underestimated as the percentage recovery from spiked samples was very low with the extraction method employed

  15. Role of the Indian Ocean sea surface temperature in shaping the natural variability in the flow of Nile River

    NASA Astrophysics Data System (ADS)

    Siam, Mohamed S.; Wang, Guiling; Demory, Marie-Estelle; Eltahir, Elfatih A. B.

    2014-08-01

    A significant fraction of the inter-annual variability in the Nile River flow is shaped by El Niño Southern Oscillation (ENSO). Here, we investigate a similar role for the Indian Ocean (IO) sea surface temperature (SST) in shaping the inter-annual variability of the Nile River flow. Using observations of global SST distribution and river flow in addition to atmospheric general circulation model sensitivity experiments, we show that North and Middle IO SSTs play a significant intermediate role in the teleconnection between ENSO and the Nile flow. Applying partial coherency analyses, we demonstrate that the connection between North and Middle IO SSTs and Nile flow is strongly coupled to ENSO. During El Niño events, SST in the North and Middle IO increases in response to the warming in the Tropical Eastern Pacific Ocean and forces a Gill-type circulation with enhanced westerly low-level flow over East Africa and the Western IO. This anomalous low-level flow enhances the low-level flux of air and moisture away from the Upper Blue Nile (UBN) basin resulting in reduction of rainfall and river flow. SSTs in the South IO also play a significant role in shaping the variability of the Nile flow that is independent from ENSO. A warming over the South IO, generates a cyclonic flow in the boundary layer, which reduces the cross-equatorial meridional transport of air and moisture towards the UBN basin, favoring a reduction in rainfall and river flow. This independence between the roles of ENSO and South IO SSTs allows for development of new combined indices of SSTs to explain the inter-annual variability of the Nile flow. The proposed teleconnections have important implications regarding mechanisms that shape the regional impacts of climate change over the Nile basin.

  16. [West Nile fever/encephalitis].

    PubMed

    Takasaki, Tomohiko

    2007-12-01

    West Nile virus (WNV), a member of the family Flaviviridae (genus Flavivirus), is a mosquito-borne virus first isolated in 1937 in the West Nile district of Uganda. The disease in humans is characterized by a dengue-like illness with fever, and a more severe form is characterized by central nervous system involvement, including encephalitis, meningitis, and myelitis. WN encephalitis was first reported in the Western Hemisphere in the summer of 1999, there was an outbreak in New York City. Epidemic WNV strains in North America are severely pathogenic, however, attenuated WNV strains were found in Texas and Mexico in 2003. The principal vectors of WNV transmission in North America are Culex. pipiens, Cx. Quinquefasciatus, Cx. restuans, Cx salinarius and Cx talsalis. The number of WN fever case has exceeded 27,000 since 1999 in the United States and 4,600 since 2002 in Canada. The first imported case of West Nile fever in Japan was confirmed in September, 2005. The patient had returned to Japan from the United States and developed symptoms the next day. There is currently no WN vaccine for use in humans. An inactivated WNV vaccine for use in horses has been available since 2001. A DNA vaccine, a chimeric live attenuated vaccine, and a recombinant vaccine have also been licensed for use in horses.

  17. Hydro-economic Risk Assessment in the Eastern Nile River Basin

    NASA Astrophysics Data System (ADS)

    Arjoon, D.; Tilmant, A.; Mohamed, Y.

    2013-12-01

    In 2011, the Ethiopian government announced plans for the construction of the Grand Renaissance Dam (GRD) on the Blue Nile, just east of its border with Sudan, at a cost of almost 5 billion dollars. The project is expected to generate over 15 TWh of energy and will include a reservoir of more than 60 km3 capacity, which roughly corresponds to the average annual flow of the Blue Nile. This project is part of a larger scheme, by the government, to expand its hydroelectric power capacity, however, the scheme faces strong opposition from downstream Egypt and Sudan. Egypt and Sudan are highly dependent on flows that originate in Ethiopia (it has been estimated that 86% of Nile flow originates in the Ethiopian highlands). The Ethiopian government argues that the dam would supply electricity for Ethiopians as well as generate surplus energy for export to neighboring countries. The Ethiopians also argue that the huge reservoir would generate positive externalities downstream by reducing floods and providing more constant and predictable lows. This study attempts to provide an independent analysis of the hydrologic and economic risks faced by downstream countries when GRD will be online. To achieve this, an integrated, stochastic hydro-economic model of the entire Eastern Nile basin is used to analyze various development and management scenarios. The results indicate that if countries agree to co- operative management of the Eastern Nile River basin, GRD would indeed significantly increase basin-wide benefits, especially in Ethiopia and in Sudan. An alternative management scenario, whereby GRD would be operated by Sudan and Egypt, does not yield significant economic gains in these countries. However, massive unilateral irrigation developments in Ethiopia will be detrimental for all countries, including Ethiopia itself, due to the huge opportunity costs involved.

  18. A distal 140 kyr sediment record of Nile discharge and East African monsoon variability

    NASA Astrophysics Data System (ADS)

    Ehrmann, Werner; Schmiedl, Gerhard; Seidel, Martin; Krüger, Stefan; Schulz, Hartmut

    2016-03-01

    Clay mineral assemblages in a sediment core from the distal Nile discharge plume off Israel have been used to reconstruct the late Quaternary Nile sediment discharge into the eastern Mediterranean Sea (EMS). The record spans the last ca. 140 kyr. Smectite abundances indicate the influence of the Blue Nile and the Atbara River that have their headwaters in the volcanic rocks of the Ethiopian Highlands. Kaolinite abundances indicate the influence of wadis, which contribute periodically to the suspension load of the Nile. Due to the geographical position, the climate and the sedimentary framework of the EMS is controlled by two climate systems. The long-term climate regime was governed by the African monsoon that caused major African humid periods (AHPs) with enhanced sediment discharge at 132 to < 126 (AHP 5), 116 to 99 (AHP4), and 89 to 77 ka (AHP3). They lasted much longer than the formation of the related sapropel layers S5 (> 2 kyr), S4 (3.5 kyr), and S3 (5 kyr). During the last glacial period (Marine Isotope Stages (MISs) 4-2), the long-term changes in the monsoonal system were superimposed by millennial-scale changes in an intensified midlatitude glacial system. This climate regime caused short but pronounced drought periods in the Nile catchment, which are linked to Heinrich events and alternate with more humid interstadials. The clay mineral record further implies that feedback mechanisms between vegetation cover and sediment discharge of the Nile are detectable but of minor importance for the sedimentary record in the southeastern Mediterranean Sea during the investigated African humid periods.

  19. A distal 145 ka sediment record of Nile discharge and East African monsoon variability

    NASA Astrophysics Data System (ADS)

    Ehrmann, W.; Schmiedl, G.; Seidel, M.; Krüger, S.; Schulz, H.

    2015-09-01

    Clay mineral assemblages in a sediment core from the distal Nile discharge plume off Israel have been used to reconstruct the late Quaternary Nile sediment discharge into the Eastern Mediterranean Sea (EMS). The record spans the last ca. 145 ka. Smectite abundances indicate the influence of the Blue Nile and Atbara that have their headwaters in the volcanic rocks of the Ethiopian highlands. Kaolinite abundances indicate the influence of wadis, which contribute periodically to the suspension load of the Nile. Due to the geographical position, the climate and the sedimentary framework of the EMS is controlled by two climate systems. The long-term climate regime was governed by the African monsoon that caused major humid periods with enhanced sediment discharge at 132 to < 122 ka (AHP 5), 113 to 104 ka (AHP 4), and 86 to 74 ka (AHP 3). They lasted much longer than the formation of the related sapropel layers S5, S4 and S3. During the last glacial period (MIS 4-2) the long-term changes of the monsoonal system were superimposed by millennial-scale changes of an intensified mid-latitude glacial system. This climate regime caused short but pronounced drought periods in the Nile catchment, which are linked to Heinrich Events and alternate with more humid interstadials. The clay mineral record further implies that feedback mechanisms between vegetation cover and sediment discharge of the Nile are detectable but of minor importance for the sedimentary record in the southeastern Mediterranean Sea during the investigated African Humid Periods.

  20. Neodymium Isotope data for Foraminifera Indicates Increased Nile Outflow During Mediterranean Anoxic Events

    NASA Astrophysics Data System (ADS)

    Scrivner, A. E.; Vance, D.; Rohling, E. J.

    2001-12-01

    The environmental conditions leading to deep water anoxia in the Eastern Mediterranean during sapropel formation remain controversial. It is broadly accepted that sapropels are the result of either water column stagnation or increased export production, or both. Oxygen isotopes indicate reduced surface-water salinities during sapropel formation, which would have facilitated deep-water stagnation via convective stabilisation of the water column. A number of sources for the additional freshwater have been proposed, including glacial meltwater influx, increased outflow from European rivers, increased precipitation over the Mediterranean region as a whole, and increased Nile outflow due to intensification of the African monsoon. Oxygen isotopes by themselves cannot fully distinguish between these various possibilities. Though the exact mode of incorporation of neodymium (Nd) into foraminiferal tests remains a matter of debate, Nd isotopes in sedimentary planktonic foraminifera clearly record those in surface seawater and not any other part of the water column or the sediment1,2. Here we present Nd isotopic data for both the present-day Nile and for sedimentary foraminifera from ODP core 967, which demonstrate a significant increase in Nile outflow during the formation of sapropel S5. Samples of Nile river water were collected from the Sudan in the dry season and analysed for neodymium isotope compositions. These analyses clearly show that the River Nile has both a very high neodymium concentration compared to the Mediterranean and a distinct 143Nd/144Nd ratio. \\epsilonNd (defined as ((143Nd/144Ndsample)/(143Nd/ 144NdCHUR)-1)\\times104) for the main Nile around and below Khartoum is -3. In the wet season (sampling in progress), the Blue Nile (\\epsilonNd = +1) dominates over the White Nile (\\epsilonNd = -16) and the total Nile discharge is vastly greater, so that the annually-integrated \\epsilonNd of the main Nile should be even higher than -3. In contrast, the

  1. Blue Laser.

    DTIC Science & Technology

    1985-12-01

    HOLLOW CATHODE LASER FABRICATION 13 4. EXPERIENCE WITH THE BLUE LASER 18 4.1 Operational and Processing Experience 18 4.2 Performance Testing 20 5...34 -. - . •. SECTION 3 BLUE HOLLOW CATHODE LASER FABRICATION This section presents an overview of the steps taken in creating a HCL. There is...to the laser assembly. These steps can actually be considered as the final steps in laser fabrication because some of them involve adding various

  2. West Nile virus and "poliomyelitis".

    PubMed

    Sejvar, James J

    2004-07-27

    West Nile virus (WNV) has recently been associated with a syndrome of acute flaccid paralysis. Most cases of WNV-associated weakness have clinical, histopathologic, and electrophysiologic characteristics indistinguishable from those of poliomyelitis caused by infection with poliovirus. There is debate about the nomenclature of this manifestation of WNV infection. An historical perspective of the term "poliomyelitis" suggests that the term "WNV poliomyelitis" seems appropriate, but members of the neurologic and infectious disease communities should engage in discussion regarding the terminology of this syndrome.

  3. West Nile Virus: an overview.

    PubMed

    Hale, Deborah

    2015-05-01

    West Nile Virus is the most frequent cause of arboviral disease in the United States. It was first identified in the United States in 1999. Since that time, each of the 48 contiguous states in the United States has seen the disease, and it has been found in 96% of the U.S. counties in infected humans, mosquitoes, birds, horses, or other mammals. Although most often the disease resolves on its own, patients can develop serious and life-threatening complications, and may need further monitoring and treatment. This article reviews the prevalence, transmission, signs and symptoms, complications, treatment, surveillance, and prevention of the disease.

  4. West Nile virus and the climate.

    PubMed

    Epstein, P R

    2001-06-01

    West Nile virus is transmitted by urban-dwelling mosquitoes to birds and other animals, with occasional "spillover" to humans. While the means by which West Nile virus was introduced into the Americas in 1999 remain unknown, the climatic conditions that amplify diseases that cycle among urban mosquitoes, birds, and humans are warm winters and spring droughts. This information can be useful in generating early warning systems and mobilizing timely and the most environmentally friendly public health interventions. The extreme weather conditions accompanying long-term climate change may also be contributing to the spread of West Nile virus in the United States and Europe.

  5. West Nile Virus and wildlife

    USGS Publications Warehouse

    Marra, P.P.; Griffing, S.; Caffrey, C.; Kilpatrick, A.M.; McLean, R.; Brand, C.; Saito, E.; Dupuis, A.P.; Kramer, Laura; Novak, R.

    2004-01-01

    West Nile virus (WNV) has spread rapidly across North America, resulting in human deaths and in the deaths of untold numbers of birds, mammals, and reptiles. The virus has reached Central America and the Caribbean and may spread to Hawaii and South America. Although tens of thousands of birds have died, and studies of some bird species show local declines, few regionwide declines can be attributed to WNV. Predicting future impacts of WNV on wildlife, and pinpointing what drives epidemics, will require substantial additional research into host susceptibility, reservoir competency, and linkages between climate, mosquitoes, and disease. Such work will entail a collaborative effort between scientists in governmental research groups, in surveillance and control programs, and in nongovernmental organizations. West Nile virus was not the first, and it will not be the last, exotic disease to be introduced to the New World. Its spread in North America highlights the need to strengthen animal monitoring programs and to integrate them with research on disease ecology.

  6. Blue gods, blue oil, and blue people.

    PubMed

    Fairbanks, V F

    1994-09-01

    Studies of the composition of coal tar, which began in Prussia in 1834, profoundly affected the economies of Germany, Great Britain, India, and the rest of the world, as well as medicine and surgery. Such effects include the collapse of the profits of the British indigo monopoly, the growth in economic power of Germany based on coal tar chemistry, and an economic crisis in India that led to more humane tax laws and, ultimately, the independence of India and the end of the British Empire. Additional consequences were the development of antiseptic surgery and the synthesis of a wide variety of useful drugs that have eradicated infections and alleviated pain. Many of these drugs, particularly the commonly used analgesics, sulfonamides, sulfones, and local anesthetics, are derivatives of aniline, originally called "blue oil" or "kyanol." Some of these aniline derivatives, however, have also caused aplastic anemia, agranulocytosis, and methemoglobinemia (that is, "blue people"). Exposure to aniline drugs, particularly when two or three aniline drugs are taken concurrently, seems to be the commonest cause of methemoglobinemia today.

  7. Drought May Beckon Bigger West Nile Outbreaks

    MedlinePlus

    ... affect transmission of the virus between mosquitoes and birds by stressing birds or changing where they gather. Mosquitoes become infected ... West Nile virus when they feed on infected birds, according to the U.S. Centers for Disease Control ...

  8. West Nile virus: North American experience

    USGS Publications Warehouse

    Hofmeister, Erik K.

    2011-01-01

    West Nile virus, a mosquito-vectored flavivirus of the Japanese encephalitis serogroup, was first detected in North America following an epizootic in the New York City area in 1999. In the intervening 11 years since the arrival of the virus in North America, it has crossed the contiguous USA, entered the Canadian provinces bordering the USA, and has been reported in the Caribbean islands, Mexico, Central America and, more recently, South America. West Nile virus has been reported in over 300 species of birds in the USA and has caused the deaths of thousands of birds, local population declines of some avian species, the clinical illness and deaths of thousands of domestic horses, and the clinical disease in over 30 000 Americans and the deaths of over 1000. Prior to the emergence of West Nile virus in North America, St. Louis encephalitis virus and Dengue virus were the only other known mosquito-transmitted flaviviruses in North America capable of causing human disease. This review will discuss the North American experience with mosquito-borne flavivirus prior to the arrival of West Nile virus, the entry and spread of West Nile virus in North America, effects on wild bird populations, genetic changes in the virus, and the current state of West Nile virus transmission.

  9. West Nile Virus in California

    PubMed Central

    Lothrop, Hugh; Chiles, Robert; Madon, Minoo; Cossen, Cynthia; Woods, Leslie; Husted, Stan; Kramer, Vicki; Edman, John

    2004-01-01

    West Nile virus (WNV) was first isolated in California during July 2003 from a pool of Culex tarsalis collected near El Centro, Imperial County. WNV transmission then increased and spread in Imperial and Coachella Valleys, where it was tracked by isolation from pools of Cx. tarsalis, seroconversions in sentinel chickens, and seroprevalence in free-ranging birds. WNV then dispersed to the city of Riverside, Riverside County, and to the Whittier Dam area of Los Angeles County, where it was detected in dead birds and pools of Cx. pipiens quinquefasciatus. By October, WNV was detected in dead birds collected from riparian corridors in Los Angeles, west to Long Beach, and through inland valleys south from Riverside to San Diego County. WNV was reported concurrently from Arizona in mid-August and from Baja, Mexico, in mid-November. Possible mechanisms for virus introduction, amplification, and dispersal are discussed. PMID:15496236

  10. Evaluation of High-Resolution Satellite Rainfall Products over the Nile Basin for Climatologic and Hydrologic Applications

    NASA Astrophysics Data System (ADS)

    Habib, E. H.; Haile, A.; Elsaadani, M.; Elshamy, M. E.; Amin, D.; Kuligowski, R. J.

    2010-12-01

    This study presents an evaluation of high-resolution rainfall estimates over the Nile Basin in Africa. The focus of the evaluation is two-fold: (1) can the satellite-rainfall products capture the overall climatological patterns and trends over the basin?, and (2) how and under what circumstances do these products support hydrologic predictions when being used as to drive a basin-wide hydrologic forecasting model? The products under examination are: the ‘Tropical Rainfall Measuring Mission (TRMM) and other sources’ (TRMM-3B42) product, and the National Oceanographic and Atmospheric Administration Climate Prediction Center (NOAA-CPC) product which is based on the CPC morphing technique (CMORPH). Over most parts of the Nile basin that are situated north of the equator, the CMORPH product shows a wet bias while the TRMM-3B42 product shows a dry bias. The estimates from both products were within the range of the climatologic records over parts of the basin around the equator. Both products reproduced the diurnal cycle of rain occurrence over the Lake Tana basin (the source of the Blue Nile) except over the mountains and the Lake shore. However, the TRMM-3B42 product underestimated the rainfall amounts in this basin. The satellite products captured the contrasting patterns of the diurnal cycles of rain occurrence and amount over the surroundings of Lake Victoria (the source of the White Nile). The second part of the evaluation focused on evaluating the possible improvements in streamflow predictions that are produced by the Nile Forecasting System (NFS) operated by the Nile Forecasting Center in Cairo, Egypt. The results suggest that that the performance of a basin-wide hydrologic model of the Nile river significantly improves when the CMORPH estimates serve as the main rainfall input compared to IR-based estimates traditionally used in the NFS model. In the Blue Nile basin, the relative volume error of the simulated flow decreased from -40 % when IR-based estimates

  11. Water and Regional Stability: The Nile a Case Study

    DTIC Science & Technology

    2011-03-24

    of the Nile River basin include the Hydromet Survey (1967-1992) and Technical Cooperation Committee for the Promotion of the Development and...Environmental Protection of the Nile Basin (TECCONILE) (1992-1998) The Hydromet Survey was a mechanism for Riparians along the Nile River to receive

  12. 21 CFR 866.3940 - West Nile virus serological reagents.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false West Nile virus serological reagents. 866.3940... virus serological reagents. (a) Identification. West Nile virus serological reagents are devices that consist of antigens and antisera for the detection of anti-West Nile virus IgM antibodies, in human serum...

  13. 21 CFR 866.3940 - West Nile virus serological reagents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false West Nile virus serological reagents. 866.3940... virus serological reagents. (a) Identification. West Nile virus serological reagents are devices that consist of antigens and antisera for the detection of anti-West Nile virus IgM antibodies, in human serum...

  14. 21 CFR 866.3940 - West Nile virus serological reagents.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false West Nile virus serological reagents. 866.3940... virus serological reagents. (a) Identification. West Nile virus serological reagents are devices that consist of antigens and antisera for the detection of anti-West Nile virus IgM antibodies, in human serum...

  15. 21 CFR 866.3940 - West Nile virus serological reagents.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false West Nile virus serological reagents. 866.3940... virus serological reagents. (a) Identification. West Nile virus serological reagents are devices that consist of antigens and antisera for the detection of anti-West Nile virus IgM antibodies, in human serum...

  16. 21 CFR 866.3940 - West Nile virus serological reagents.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false West Nile virus serological reagents. 866.3940... (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Serological Reagents § 866.3940 West Nile virus serological reagents. (a) Identification. West Nile virus serological reagents are devices that...

  17. Holocene palaeo-environments on the western coast of the Nile Delta: local and basin-wide forcing factors

    NASA Astrophysics Data System (ADS)

    Flaux, Clément; Véron, Alain; Marriner, Nick; el-Assal, Mena; Claude, Christelle; Morhange, Christophe

    2014-05-01

    The Canopic branch, which is today either silted up and cultivated or re-used in the modern drainage network, was the main channel for the western Nile Delta during Antiquity. Ancient Canopic flow used to supply the water network on the deltaic margin, including secondary tributaries, the Maryut lake, and irrigation agriculture and urban needs. We present new data obtained from a sediment core taken close to the palaeo-Canopic channel. Lead (Pb) isotopic analyses of bulk sediments, together with sedimentology, macro- and micro-fauna assemblages, magnetic susceptibility and radiocarbon dates provide evidence for environmental changes at the Canopic mouth in addition to changes in Nile sediment sources during the last 6000 years. Alternation of estuarine to lagoonal and peaty biofacies have recorded stages of transgression and progradation. 206Pb/207Pb analyses suggest a change in dominant sediment load from the White Nile to Blue Nile between 6000 and 5000 years cal. BP. The dataset is then compared and contrasted with previous studies, including: (1) a dense grid of dated bio-sedimentological cores data from the northwestern Nile Delta; (2) strontium isotope records of water and sediment fluxes on the delta; and (3) geochemical records from offshore sediment cores. Our analysis attempts to date and discriminate between basin-wide and regional to local forcing agents driving environmental changes at the mouth of the Canopic. The three main factors discussed will include climatic forcing of Nile flow and load changes, relative sea-level variations, and human impacts on the Canopic flow.

  18. City Lights Illuminate the Nile

    NASA Image and Video Library

    2017-09-27

    NASA image acquired October 13, 2012 The Nile River Valley and Delta comprise less than 5 percent of Egypt’s land area, but provide a home to roughly 97 percent of the country’s population. Nothing makes the location of human population clearer than the lights illuminating the valley and delta at night. On October 13, 2012, the Visible Infrared Imaging Radiometer Suite (VIIRS) on the Suomi NPP satellite captured this nighttime view of the Nile River Valley and Delta. This image is from the VIIRS “day-night band,” which detects light in a range of wavelengths from green to near-infrared and uses filtering techniques to observe signals such as gas flares, auroras, wildfires, city lights, and reflected moonlight. The city lights resemble a giant calla lily, just one with a kink in its stem near the city of Luxor. Some of the brightest lights occur around Cairo, but lights are abundant along the length of the river. Bright city lights also occur along the Suez Canal and around Tel Aviv. Away from the lights, however, land and water appear uniformly black. This image was acquired near the time of the new Moon, and little moonlight was available to brighten land and water surfaces. NASA Earth Observatory image by Jesse Allen and Robert Simmon, using VIIRS Day-Night Band data from the Suomi National Polar-orbiting Partnership. Suomi NPP is the result of a partnership between NASA, the National Oceanic and Atmospheric Administration, and the Department of Defense. Caption by Michon Scott. Instrument: Suomi NPP - VIIRS Credit: NASA Earth Observatory Click here to view all of the Earth at Night 2012 images Click here to read more about this image NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency

  19. Blue Saturn

    NASA Image and Video Library

    2004-03-19

    Bands and spots in Saturn's atmosphere, including a dark band south of the equator with a scalloped border, are visible in this image from the Cassini-Huygens spacecraft. The narrow angle camera took the image in blue light on Feb. 29, 2004. The distance to Saturn was 59.9 million kilometers (37.2 million miles). The image scale is 359 kilometers (223 miles) per pixel. Three of Saturn's moons are seen in the image: Enceladus (499 kilometers, or 310 miles across) at left; Mimas (398 kilometers, or 247 miles across) left of Saturn's south pole; and Rhea (1,528 kilometers, or 949 miles across) at lower right. The imaging team enhanced the brightness of the moons to aid visibility. The BL1 broadband spectral filter (centered at 451 nanometers) allows Cassini to "see" light in a part of the spectrum visible as the color blue to human eyes. Scientist can combine images made with this filter with those taken with red and green filters to create full-color composites. Scientists can also assess cloud heights by combining images from the blue filter with images taken in other spectral regions. For example, the bright clouds that form the equatorial zone are the highest in altitude and have pressures at their tops of about one quarter of Earth's atmospheric pressure at sea level. The cloud tops at middle latitudes are lower in altitude and have higher pressures of about half that found at sea level. Analysis of Saturn images like this one will be extremely useful to researchers assessing cloud altitudes during the Cassini-Huygens mission. http://photojournal.jpl.nasa.gov/catalog/PIA05383

  20. 21,000 years of Ethiopian African monsoon variability recorded in sediments of the western Nile deep-sea fan: impact of the Nile freshwater inflow for the Mediterranean thermo-haline circulation

    NASA Astrophysics Data System (ADS)

    Revel, Marie; Colin, Christophe; Bernasconi, Stephano; Combourieu-Nebout, Nathalie; Ducassou, Emmanuelle; Rolland, Yann; Bosch, Delphine

    2014-05-01

    The Nile delta sedimentation constitutes a continuous high resolution (1.6 mm/year) record of Ethiopian African monsoon regime intensity. Multiproxy analyses performed on core MS27PT recovered in hemipelagic Nile sediment margin (<90 km outward of the Rosetta mouth of the Nile) allow the quantification of the Saharan aeolian dust and the Blue/White Nile River suspended matter frequency fluctuations during the last 21 cal. ka BP. The radiogenic Sr and Nd isotopes, clay mineralogy, bulk elemental composition and palynological analyses reveal large changes in source components, oscillating between a dominant aeolian Saharan contribution during the LGM and the Late Holocene (~4 to 2 cal. ka BP), a dominant Blue/Atbara Nile River contribution during the early Holocene (15 to 8.4 cal. ka BP) and a probable White Nile River contribution during the Middle Holocene (8.4 to 4 cal. ka BP). The following main features are highlighted: 1. The rapid shift from the LGM arid conditions to the African Humid Period (AHP) started at about 15 cal. ka BP. AHP extends until 8.4 cal. ka BP, and we suggest that the Ethiopian African Monsoon maximum between 12 and 8 cal. ka BP is responsible for a larger Blue/Atbara Nile sediment load and freshwater input into the Eastern Mediterranean Sea. 2. The transition between the AHP and the arid Late Holocene is gradual and occurs in two main phases between 8.4 and 6.5 cal. ka BP and 6.5 to 3.2 cal. ka BP. We suggest that the main rain belt shifted southward from 8.4 to ~4 cal. ka BP and was responsible for progressively reduced sediment load and freshwater input into the eastern Mediterranean Sea. 3. The aridification along the Nile catchments occurred from ~4 to 2 cal. ka BP. A dry period, which culminates at 3.2 cal. ka BP, and seems to coincide with a re-establishment of increased oceanic primary productivity in the western Mediterranean Sea. We postulate that the decrease in thermo-haline water Mediterranean circulation could be part of a

  1. Impacts of West Nile Virus on wildlife

    USGS Publications Warehouse

    Saito, E.K.; Wild, M.A.

    2004-01-01

    The recent epidemic of West Nile virus in the United States proved to be unexpectedly active and was the largest epidemic of the virus ever recorded. Much remains to be discovered about the ecology and epidemiology of West Nile virus in the United States, including which species are important in maintaining the virus in nature, why some species are more susceptible to lethal infection, and what environmental factors are important in predicting future epidemics. These factors will likely vary regionally, depending on local ecological characteristics. Until scientists better understand the virus and factors influencing its activity, predicting its effects for future seasons is impossible. However, experts are certain about one thing: West Nile virus is here to stay.

  2. West Nile Virus: Review of the Literature

    PubMed Central

    Petersen, Lyle R.; Brault, Aaron C.; Nasci, Roger S.

    2015-01-01

    IMPORTANCE Since its introduction in North America in 1999,West Nile virus has produced the 3 largest arboviral neuroinvasive disease outbreaks ever recorded in the United States. OBJECTIVE To review the ecology, virology, epidemiology, clinical characteristics, diagnosis, prevention, and control of West Nile virus, with an emphasis on North America. EVIDENCE REVIEW PubMed electronic database was searched through February 5, 2013. United States national surveillance data were gathered from the Centers for Disease Control and Prevention. FINDINGS West Nile virus is now endemic throughout the contiguous United States, with 16 196 human neuroinvasive disease cases and 1549 deaths reported since 1999. More than 780 000 illnesses have likely occurred. To date, incidence is highest in the Midwest from mid-July to early September. West Nile fever develops in approximately 25% of those infected, varies greatly in clinical severity, and symptoms may be prolonged. Neuroinvasive disease (meningitis, encephalitis, acute flaccid paralysis) develops in less than 1% but carries a fatality rate of approximately 10%. Encephalitis has a highly variable clinical course but often is associated with considerable long-term morbidity. Approximately two-thirds of those with paralysis remain with significant weakness in affected limbs. Diagnosis usually rests on detection of IgM antibody in serum or cerebrospinal fluid. Treatment is supportive; no licensed human vaccine exists. Prevention uses an integrated pest management approach, which focuses on surveillance, elimination of mosquito breeding sites, and larval and adult mosquito management using pesticides to keep mosquito populations low. During outbreaks or impending outbreaks, emphasis shifts to aggressive adult mosquito control to reduce the abundance of infected, biting mosquitoes. Pesticide exposure and adverse human health events following adult mosquito control operations for West Nile virus appear negligible. CONCLUSIONS AND

  3. Liquefaction potential of Nile delta, Egypt

    NASA Astrophysics Data System (ADS)

    Fergany, Elsayed; Omar, Khaled

    2017-06-01

    Understanding how sedimentary basins respond to seismic-wave energy generated by earthquake events is a significant concern for seismic-hazard estimation and risk analysis. The main goal of this study is assessing the vulnerability index, Kg, as an indicator for liquefaction potential sites in the Nile delta basin based on the microtremor measurements. Horizontal to Vertical spectral ratio analyses (HVSR) of ambient noise data, which was conducted in 2006 at 120 sites covering the Nile delta from south to north were reprocessed using Geopsy software. HVSR factors of amplification, A, and fundamental frequency, F, were calculated and Kg was estimated for each measurement. The Kg value varies widely from south toward north delta and the potential liquefaction places were estimated. The higher vulnerability indices are associated with sites located in southern part of the Nile delta and close to the branches of Nile River. The HVSR factors were correlated with geologic setting of the Nile delta and show good correlations with the sediment thickness and subsurface stratigraphic boundaries. However, we note that sites located in areas that have greatest percentage of sand also yielded relatively high Kg values with respect to sites in areas where clay is abundant. We concluded that any earthquake with ground acceleration more than 50 gal at hard rock can cause a perceived deformation of sandy sediments and liquefaction can take place in the weak zones of Kg ≥ 20. The worst potential liquefaction zones (Kg > 30) are frequently joined to the Damietta and Rosetta Nile River branches and south Delta where relatively coarser sand exists. The HVSR technique is a very sensitive tool for lithological stratigraphy variations in two dimensions and varying liquefaction susceptibility.

  4. Geological evolution and incision history of the Gorge of the Nile on Ethiopian Plateau from remote sensing and geographic information system analysis, and field studies

    NASA Astrophysics Data System (ADS)

    Gani, Nahid Ds

    Integrated remote sensing and Geographic System Analysis (GIS) analysis has proven to be an effective approach in geological studies of vast, inaccessible areas with dispersed field information. Such an approach has been undertaken to study the 1.6 km deep Gorge of the Nile formed by the Blue Nile, situated on the Northwestern Ethiopian Plateau. The analysis of Digital Elevation Models (DEMs) extracted from the Shuttle Radar Topography Mission (SRTM) and the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) for river geomorphic information shows a dramatic decrease in average gradient and an increase in valley width, depth and asymmetry from headwater to downstream along the Gorge of the Nile. The integration of orbital-optical and radar remote sensing data including ASTER, Landsat Thematic Mapper (TM), RADARSAT, and DEMs with field data to trace lithological units and structural features of the study area has helped in delineating geologic history of the area as well as the geologic controls on the formation of the Gorge of the Nile. This study has revealed that the Blue Nile Basin evolved in three main phases: (1) Pre-sedimentation phase involving pre-rift peneplanation of the Neoproterozoic basement rocks; (2) Post-rift, Mesozoic sedimentation with repeated marine transgressions and regressions, including fluvial sandstones, and marine limestone and glauconitic mudstones; (3) Post-sedimentation phase which involve extensive volcanism from Middle Oligocene to Quaternary related to the Afar mantle plume. These stratigraphic units are deformed by normal faults of NW and NE-trends with a series of horsts and grabens that are thought to be formed by polyphase deformation and/or stress compartmentalization, indicating that the Blue Nile Basin is located within an extensional regime. Analysis of DEMs with GIS has been used to study the timing, pattern, depth and rate of incision in the evolution of the Gorge of the Nile as well as the Blue Nile

  5. The Blue Bottle Revisited.

    ERIC Educational Resources Information Center

    Vandaveer, Walter R., IV; Mosher, Mel

    1997-01-01

    Presents a modification of the classic Blue Bottle demonstration that involves the alkaline glucose reduction of methylene blue. Uses other indicators in the classic Blue Bottle to produce a rainbow of colors. (JRH)

  6. The Blue Bottle Revisited.

    ERIC Educational Resources Information Center

    Vandaveer, Walter R., IV; Mosher, Mel

    1997-01-01

    Presents a modification of the classic Blue Bottle demonstration that involves the alkaline glucose reduction of methylene blue. Uses other indicators in the classic Blue Bottle to produce a rainbow of colors. (JRH)

  7. Tracking Nile Delta vulnerability to Holocene change.

    PubMed

    Marriner, Nick; Flaux, Clément; Morhange, Christophe; Stanley, Jean-Daniel

    2013-01-01

    Understanding deltaic resilience in the face of Holocene climate change and human impacts is an important challenge for the earth sciences in characterizing the full range of present and future wetland responses to global warming. Here, we report an 8000-year mass balance record from the Nile Delta to reconstruct when and how this sedimentary basin has responded to past hydrological shifts. In a global Holocene context, the long-term decrease in Nile Delta accretion rates is consistent with insolation-driven changes in the 'monsoon pacemaker', attested throughout the mid-latitude tropics. Following the early to mid-Holocene growth of the Nile's deltaic plain, sediment losses and pronounced erosion are first recorded after ~4000 years ago, the corollaries of falling sediment supply and an intensification of anthropogenic impacts from the Pharaonic period onwards. Against the backcloth of the Saharan 'depeopling', reduced river flow underpinned by a weakening of monsoonal precipitation appears to have been particularly conducive to the expansion of human activities on the delta by exposing productive floodplain lands for occupation and irrigation agriculture. The reconstruction suggests that the Nile Delta has a particularly long history of vulnerability to extreme events (e.g. floods and storms) and sea-level rise, although the present sediment-starved system does not have a direct Holocene analogue. This study highlights the importance of the world's deltas as sensitive archives to investigate Holocene geosystem responses to climate change, risks and hazards, and societal interaction.

  8. Evaluation of West Nile Virus Education Campaign

    PubMed Central

    Neuberger, John S.; Hansen, Gail; Fox, Michael H.

    2005-01-01

    We evaluated the 2003 Kansas West Nile virus public education campaign. Awareness was widespread but compliance was low. Spanish-speaking persons were poorly informed. Relevant factors included population segment variability, campaign content, media choice, and materials delivery methods. PMID:16318730

  9. Nile perch: the great lake experiment.

    PubMed

    Ogutu-ohwayo, R

    1998-01-01

    In order to improve the fishery of Lake Victoria, a large predatory fish, the Nile perch (Lates niloticus), was introduced into the lake to feed on the smaller but abundant haplochromines, thereby producing a larger fish for food consumption. Originally the lake had a very high fish species diversity, dominated by more than 300 species of haplochromine cichlids; however, they were too small to be exploited for food. It took about 20 years for the population of the Nile perch in the lake to increase significantly. Although increased fish production has benefited riparian communities by providing revenue, employment, and food, the introduction of the Nile perch has also resulted in extinction and has transformed the lake ecosystem. In response to the concern caused by the introduction of the Nile perch, the deteriorating water quality, and the need to sustain the lucrative fishery, the governments of Uganda, Kenya, and Tanzania have initiated the multisectoral Lake Victoria Environment Management Programme. Its goals are to control the loading of nutrients and contaminants into the lake, manage land use in the catchment area, manage the introduced fish species, conserve biodiversity, and control the spread of water hyacinths.

  10. Does The Nile Reflect Solar Variability?

    NASA Technical Reports Server (NTRS)

    Ruzmaikin, Alexander; Feynman, Joan; Yung, Yuk

    2006-01-01

    Historical records of the Nile water level provide a unique opportunity to investigate the possibility that solar variability influences the Earth's climate. Particularly important are the annual records of the water level, which are uninterrupted for the years 622-1470 A.D. These records are non-stationary, so that standard spectral analyses cannot adequately characterize them. Here the Empirical Mode Decomposition technique, which is designed to deal with nonstationary, nonlinear time series, becomes useful. It allows the identification of two characteristic time scales in the water level data that can be linked to solar variability: the 88 year period and a time scale of about 200 years. These time scales are also present in the concurrent aurora data. Auroras are driven by coronal mass ejections and the rate of auroras is an excellent proxy for solar variability. Analysis of auroral data contemporaneous with the Nile data shows peaks at 88 years and about 200 years. This suggests a physical link between solar variability and the low frequency variations of the Nile water level. The link involves the influence of solar variability on the North Annual Mode of atmospheric variability and its North Atlantic and Indian Oceans patterns that affect rainfall over Eastern Equatorial Africa where the Nile originates.

  11. Record of Nile seasonality in Nubian neonates.

    PubMed

    Martin, Céline; Maureille, Bruno; Amiot, Romain; Touzeau, Alexandra; Royer, Aurélien; Fourel, François; Panczer, Gérard; Flandrois, Jean-Pierre; Lécuyer, Christophe

    2017-06-01

    The oxygen isotope compositions of bones (n = 11) and teeth (n = 20) from 12 Sudanese individuals buried on Sai Island (Nubia) were analysed to investigate the registration of the evolution of the Nile environment from 3700 to 500 years BP and the potential effects of ontogeny on the oxygen isotope ratios. The isotopic compositions were converted into the composition of drinking water, ultimately originating from the Nile. δ(18)O values decrease during ontogeny; this is mainly related to breastfeeding and physiology. Those of neonates present very large variations. Neonates have a very high bone turnover and are thus able to record seasonal δ(18)O variations of the Nile waters. These variations followed a pattern very similar to the present one. Nile δ(18)O values increased from 1.4 to 4.4 ‰ (Vienna Standard Mean Ocean Water) from the Classic Kerma (∼3500 BP) through the Christian period (∼1000 BP), traducing a progressive drying of Northeast Africa.

  12. The question of Sudan: a hydroeconomic optimization model for the Sudanese Nile

    NASA Astrophysics Data System (ADS)

    Satti, S.; Zaitchik, B.; Siddiqui, S.

    2014-10-01

    The effects of development and the uncertainty of a changing climate in East Africa pose myriad challenges for water managers along the Blue Nile. Sudan's large irrigation potential, hydroelectric dams, and prime location within the basin mean that Sudan's water management decisions will have great social, economic and political implications within the region. At the same time, Sudan's water use options are constrained by tradeoffs between upstream irrigation developments and downstream hydropower facilities as well as by the country's commitments under existing or future transboundary water sharing agreements. Here, we present a model that can be applied to evaluate optimal allocation of surface water resources to irrigation and hydropower in the Sudanese portion of the Blue Nile. Hydrologic inputs are combined with agronomic and economic inputs to formulate an optimization model within the General Algebraic Modeling System (GAMS). A sensitivity analysis is performed by testing model response to a range of economic conditions and to changes in the volume and timing of hydrologic flows. Results indicate that changing hydroclimate inputs have the capacity to greatly influence the productivity of Sudan's water resources infrastructure. Results also show that the economically optimal volume of water consumption, and thus the importance of existing treaty constraints, is sensitive to the perceived value of agriculture relative to electricity as well as to changing hydrological conditions.

  13. A rapid-screening approach to detect and quantify microplastics based on fluorescent tagging with Nile Red

    NASA Astrophysics Data System (ADS)

    Maes, Thomas; Jessop, Rebecca; Wellner, Nikolaus; Haupt, Karsten; Mayes, Andrew G.

    2017-03-01

    A new approach is presented for analysis of microplastics in environmental samples, based on selective fluorescent staining using Nile Red (NR), followed by density-based extraction and filtration. The dye adsorbs onto plastic surfaces and renders them fluorescent when irradiated with blue light. Fluorescence emission is detected using simple photography through an orange filter. Image-analysis allows fluorescent particles to be identified and counted. Magnified images can be recorded and tiled to cover the whole filter area, allowing particles down to a few micrometres to be detected. The solvatochromic nature of Nile Red also offers the possibility of plastic categorisation based on surface polarity characteristics of identified particles. This article details the development of this staining method and its initial cross-validation by comparison with infrared (IR) microscopy. Microplastics of different sizes could be detected and counted in marine sediment samples. The fluorescence staining identified the same particles as those found by scanning a filter area with IR-microscopy.

  14. A rapid-screening approach to detect and quantify microplastics based on fluorescent tagging with Nile Red.

    PubMed

    Maes, Thomas; Jessop, Rebecca; Wellner, Nikolaus; Haupt, Karsten; Mayes, Andrew G

    2017-03-16

    A new approach is presented for analysis of microplastics in environmental samples, based on selective fluorescent staining using Nile Red (NR), followed by density-based extraction and filtration. The dye adsorbs onto plastic surfaces and renders them fluorescent when irradiated with blue light. Fluorescence emission is detected using simple photography through an orange filter. Image-analysis allows fluorescent particles to be identified and counted. Magnified images can be recorded and tiled to cover the whole filter area, allowing particles down to a few micrometres to be detected. The solvatochromic nature of Nile Red also offers the possibility of plastic categorisation based on surface polarity characteristics of identified particles. This article details the development of this staining method and its initial cross-validation by comparison with infrared (IR) microscopy. Microplastics of different sizes could be detected and counted in marine sediment samples. The fluorescence staining identified the same particles as those found by scanning a filter area with IR-microscopy.

  15. West Nile virus surveillance in East Baton Rouge Parish, Louisiana.

    PubMed

    Gleiser, Raquel M; Mackay, Andrew J; Roy, Alma; Yates, Mathew M; Vaeth, Randy H; Faget, Guy M; Folsom, Alex E; Augustine, William F; Wells, Roderick A; Perich, Michael J

    2007-03-01

    West Nile virus (WNV) was detected for the first time in Louisiana in the fall of 2001. Surveillance data collected from East Baton Rouge Parish in 2002 were examined to establish baseline data on WNV activity, to support the current design of disease surveillance programs, and to target vector control efforts in the parish. The first indications of WNV activity were from a dead Northern Cardinal collected in February and from a live male cardinal sampled on 14 March. In mosquito pools, WNV was first detected on June 11. The onset of the first human case and the first detection of WNV in sentinel chickens occurred concurrently on June 24. The number of reported human cases and minimum infection rates in mosquitoes peaked in July. WNV prevalence in wild birds increased in late August and was highest in December. WNV-positive wild birds and mosquito pools were detected an average of 31 and 59 days in advance of the onset date of reported human cases, respectively, within 5 km of the residence of a human case. Antibodies to WNV were detected in sera from 7 (Northern Cardinal, House Sparrow, Northern Mockingbird, Blue Jay, Hermit Thrush, Yellow-rumped Warbler, and White-throated Sparrow) of the 42 wild bird species tested. Wild bird serology indicated WNV activity during the winter. Out of 18 mosquito species tested, the only species found positive for WNV was Culex quinquefasciatus, a result suggesting that this species was the primary epizootic/epidemic vector.

  16. West Nile virus infection in children.

    PubMed

    Barzon, Luisa; Pacenti, Monia; Sinigaglia, Alessandro; Berto, Alessandro; Trevisan, Marta; Palù, Giorgio

    2015-01-01

    West Nile virus (WNV) is an emerging flavivirus responsible for an increasing number of outbreaks of neuroinvasive disease in North America, Europe, and neighboring countries. Almost all WNV infections in humans are transmitted through the bite of infected mosquitoes. Transmission during pregnancy and through breastfeeding has been reported, but the risk seems to be very low. West Nile disease in children is less common (1-5% of all WNV cases) and associated with milder symptoms and better outcome than in elderly individuals, even though severe neuroinvasive disease and death have been reported also among children. However, the incidence of WNV infection and disease in children is probably underestimated and the disease spectrum is not fully understood because of lack of reporting and underdiagnosis in children. Infection is diagnosed by detection of WNV-specific antibodies in serum and WNV RNA in plasma and urine. Since no effective WNV-specific drugs are available, therapy is mainly supportive.

  17. Did Nile flooding sink two ancient cities?

    PubMed

    Said, Rushdi

    2002-01-03

    The discovery of the two cities of Herakleion and East Canopus under the waters of the Bay of Abu Qir (east of Alexandria, Egypt) stirred worldwide attention when it was first announced in the summer of 2000. Their disappearance some 1,250 years ago has been ascribed by Stanley, Goddio and Schnepp to a strong Nile flood that caused riverbank failure and the destruction of the two cities, rather than to the action of earthquakes, as was first proposed when the ruins were discovered. But I believe that this interpretation is flawed, because no flood could have reached the Abu Qir Bay at the time of the disappearance of the two cities, as the Canopic branch of the Nile, along whose banks they were situated, had dried to a trickle more than 200 years earlier.

  18. Aswan Dam, Lake Nassar, Nile River, Egypt

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The Aswan Dam on the Nile River created the 500 kilometer long reservoir, seen here in sunglint. Lake Nassar (23.5N, 33.0E) was designed to control the devestating floods and alleviate the famine-producing droughts which have plagued the region for millenia. In Nov 81, as the lake was nearing capacity, drought conditions lowered the water level by about 30 meters which can clearly be seen as silt depositions on the receding eastern shoreline.

  19. West Nile Virus in Farmed Alligators

    PubMed Central

    Mauel, Michael J.; Baldwin, Charles; Burtle, Gary; Ingram, Dallas; Hines, Murray E.; Frazier, Kendal S.

    2003-01-01

    Seven alligators were submitted to the Tifton Veterinary Diagnostic and Investigational Laboratory for necropsy during two epizootics in the fall of 2001 and 2002. The alligators were raised in temperature-controlled buildings and fed a diet of horsemeat supplemented with vitamins and minerals. Histologic findings in the juvenile alligators were multiorgan necrosis, heterophilic granulomas, and heterophilic perivasculitis and were most indicative of septicemia or bacteremia. Histologic findings in a hatchling alligator were random foci of necrosis in multiple organs and mononuclear perivascular encephalitis, indicative of a viral cause. West Nile virus was isolated from submissions in 2002. Reverse transcription-polymerase chain reaction (RT-PCR) results on all submitted case samples were positive for West Nile virus for one of four cases associated with the 2001 epizootic and three of three cases associated with the 2002 epizootic. RT-PCR analysis was positive for West Nile virus in the horsemeat collected during the 2002 outbreak but negative in the horsemeat collected after the outbreak. PMID:12890319

  20. A new model of river dynamics, hydroclimatic change and human settlement in the Nile Valley derived from meta-analysis of the Holocene fluvial archive

    NASA Astrophysics Data System (ADS)

    Macklin, Mark G.; Toonen, Willem H. J.; Woodward, Jamie C.; Williams, Martin A. J.; Flaux, Clément; Marriner, Nick; Nicoll, Kathleen; Verstraeten, Gert; Spencer, Neal; Welsby, Derek

    2015-12-01

    In the Nile catchment, a growing number of site- and reach-based studies employ radiocarbon and, more recently, OSL dating to reconstruct Holocene river histories, but there has been no attempt to critically evaluate and synthesise these data at the catchment scale. We present the first meta-analysis of published and publically available radiocarbon and OSL dated Holocene fluvial units in the Nile catchment, including the delta region, and relate this to changing climate and river dynamics. Dated fluvial units are separated both geographically (into the Nile Delta and White, Blue, and Desert Nile sub-regions) and into depositional environment (floodplain and palaeochannel fills). Cumulative probability density frequency (CPDF) plots of floodplain and palaeochannel units show a striking inverse relationship during the Holocene, reflecting abrupt (<100 years) climate-related changes in flooding regime. The CPDF plot of dated floodplain units is interpreted as a record of over-bank river flows, whilst the CPDF plot of palaeochannel units reflect periods of major flooding associated with channel abandonment and contraction, as well as transitions to multi-centennial length episodes of greater aridity and low river flow. This analysis has identified major changes in river flow and dynamics in the Nile catchment with phases of channel and floodplain contraction at c. 6150-5750, 4400-4150, 3700-3450, 2700-2250, 1350-900, 800-550 cal. BC and cal. AD 1600, timeframes that mark shifts to new hydrological and geomorphological regimes. We discuss the impacts of these changing hydromorphological regimes upon riverine civilizations in the Nile Valley.

  1. Nile behaviour and Upper Palaeolithic humans in Upper Egypt

    NASA Astrophysics Data System (ADS)

    Vermeersch, Pierre M.

    2014-05-01

    There is evidence of a decreasing human occupation of the Upper Egyptian Nile valley during the MIS 5 to MIS 3 period. Whereas very large extraction sites of the Middle Stone Age have been recorded, only very few sites of the Upper Palaeolithic have been found. The best explanation of this fact is that during the Late Middle Stone Age and the Upper Palaeolithc there was nearly no need for raw materials because there was only a very restricted population present in Upper Egypt. From about 22 ka BP an important population increase is registered by the presence of numerous Late Palaeolithic sites. During the whole LGM there is abundant presence of humans along the Nile Valley in Upper Egypt. This population was mainly living from fishing. There seems to be an abrupt end of the Palaeolithic occupation after 12.8 ka BP. Until now, no sites were found in the Valley until some rare Epipaleolithic sites occur about 8.0 ka BP. It will be suggested that these population changes are influenced by the river Nile behaviour. The best interpretation of the observations in the Upper Egyptian Nile Valley is the hypothesis that at the same time that Nile flow was reduced because of the dryness in its source area, the impact of aeolian activity was increased over Northeast Africa. The increased aeolian activity by northern winds in the Fayum and Wadi Ryan during the LGM resulted in the accumulation of aeolian sand in the valley. That aeolian sand was transported along the western Nile valley cliffs until it was accumulated when the Nile Valley change it S-N direction, such as at Nag'Hammadi. At other places sand was invading the Nile valley, directly from the Western Desert, creating a damming of the Nile at several places such as Armant and Aswan. As Nile flow was quite reduced, the Nile was unable to erode all the incoming sand and the Nile water with its important clay content was dammed. At several places large lakes were created in the Nile Valley. Those lakes were an ideal

  2. West Nile virus ecology in a tropical ecosystem in Guatemala.

    PubMed

    Morales-Betoulle, Maria E; Komar, Nicholas; Panella, Nicholas A; Alvarez, Danilo; López, María R; Betoulle, Jean-Luc; Sosa, Silvia M; Müller, María L; Kilpatrick, A Marm; Lanciotti, Robert S; Johnson, Barbara W; Powers, Ann M; Cordón-Rosales, Celia

    2013-01-01

    West Nile virus ecology has yet to be rigorously investigated in the Caribbean Basin. We identified a transmission focus in Puerto Barrios, Guatemala, and established systematic monitoring of avian abundance and infection, seroconversions in domestic poultry, and viral infections in mosquitoes. West Nile virus transmission was detected annually between May and October from 2005 to 2008. High temperature and low rainfall enhanced the probability of chicken seroconversions, which occurred in both urban and rural sites. West Nile virus was isolated from Culex quinquefasciatus and to a lesser extent, from Culex mollis/Culex inflictus, but not from the most abundant Culex mosquito, Culex nigripalpus. A calculation that combined avian abundance, seroprevalence, and vertebrate reservoir competence suggested that great-tailed grackle (Quiscalus mexicanus) is the major amplifying host in this ecosystem. West Nile virus transmission reached moderate levels in sentinel chickens during 2007, but less than that observed during outbreaks of human disease attributed to West Nile virus in the United States.

  3. Methylene blue test

    MedlinePlus

    ... determine the type or to treat methemoglobinemia , a blood disorder. ... Methemoglobinemia - methylene blue test ... Normally, methylene blue quickly lowers the level of ... Some labs use different measurements or test different samples. ...

  4. The Blue Water

    ERIC Educational Resources Information Center

    Berger, J. Joel

    1973-01-01

    Describes some of the advantages of an elementary science activity in which students discover that blowing through a straw into a bromthymol blue solution changes the color to yellow. Directions are provided for preparing the bromthymol blue solution. (JR)

  5. Blue Origin testing

    NASA Image and Video Library

    2012-04-20

    NASA Administrator Charles Bolden (r) discusses the upcoming testing of Blue Origin's BE-3 engine thrust chamber assembly with Steve Knowles, Blue Origin project manager, at the E-1 Test Stand during an April 20, 2012, visit to Stennis Space Center. Blue Origin is one of NASA's partners developing innovative systems to reach low-Earth orbit.

  6. DNA Electrochemistry with Tethered Methylene Blue

    PubMed Central

    Pheeney, Catrina G.

    2012-01-01

    Methylene blue (MB′), covalently attached to DNA through a flexible C12 alkyl linker, provides a sensitive redox reporter in DNA electrochemistry measurements. Tethered, intercalated MB′ is reduced through DNA-mediated charge transport; the incorporation of a single base mismatch at position 3, 10, or 14 of a 17-mer causes an attenuation of the signal to 62 ± 3% of the well-matched DNA, irrespective of position in the duplex. The redox signal intensity for MB′–DNA is found to be least 3-fold larger than that of Nile blue (NB)–DNA, indicating that MB′ is even more strongly coupled to the π-stack. The signal attenuation due to an intervening mismatch does, however, depend on DNA film density and the backfilling agent used to passivate the surface. These results highlight two mechanisms for reduction of MB′ on the DNA-modified electrode: reduction mediated by the DNA base pair stack and direct surface reduction of MB′ at the electrode. These two mechanisms are distinguished by their rates of electron transfer that differ by 20-fold. The extent of direct reduction at the surface can be controlled by assembly and buffer conditions. PMID:22512327

  7. Tracking Nile Delta Vulnerability to Holocene Change

    PubMed Central

    Marriner, Nick; Flaux, Clément; Morhange, Christophe; Stanley, Jean-Daniel

    2013-01-01

    Understanding deltaic resilience in the face of Holocene climate change and human impacts is an important challenge for the earth sciences in characterizing the full range of present and future wetland responses to global warming. Here, we report an 8000-year mass balance record from the Nile Delta to reconstruct when and how this sedimentary basin has responded to past hydrological shifts. In a global Holocene context, the long-term decrease in Nile Delta accretion rates is consistent with insolation-driven changes in the ‘monsoon pacemaker’, attested throughout the mid-latitude tropics. Following the early to mid-Holocene growth of the Nile’s deltaic plain, sediment losses and pronounced erosion are first recorded after ~4000 years ago, the corollaries of falling sediment supply and an intensification of anthropogenic impacts from the Pharaonic period onwards. Against the backcloth of the Saharan ‘depeopling’, reduced river flow underpinned by a weakening of monsoonal precipitation appears to have been particularly conducive to the expansion of human activities on the delta by exposing productive floodplain lands for occupation and irrigation agriculture. The reconstruction suggests that the Nile Delta has a particularly long history of vulnerability to extreme events (e.g. floods and storms) and sea-level rise, although the present sediment-starved system does not have a direct Holocene analogue. This study highlights the importance of the world’s deltas as sensitive archives to investigate Holocene geosystem responses to climate change, risks and hazards, and societal interaction. PMID:23922692

  8. Wild snakes harbor West Nile virus.

    PubMed

    Dahlin, C R; Hughes, D F; Meshaka, W E; Coleman, C; Henning, J D

    2016-12-01

    West Nile virus (WNV) has a complex eco-epidemiology with birds acting as reservoirs and hosts for the virus. Less well understood is the role of reptiles, especially in wild populations. The goal of our study was to determine whether a wild population of snakes in Pennsylvania harbored WNV. Six species of snakes were orally sampled in the summer of 2013 and were tested for the presence of WNV viral RNA using RT-PCR. Two Eastern Garter Snakes, Thamnophis sirtalis sirtalis tested positive for viral RNA (2/123, 1.62%). These results indicate a possible role for snakes in the complex transmission cycle of WNV.

  9. Alligators as West Nile Virus Amplifiers

    PubMed Central

    Klenk, Kaci; Snow, Jamie; Morgan, Katrina; Bowen, Richard; Stephens, Michael; Foster, Falicia; Gordy, Paul; Beckett, Susan; Komar, Nicholas; Gubler, Duane; Bunning, Michel

    2004-01-01

    Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >5.0 log10 PFU/mL (a threshold considered infectious for Culex quinquefasciatus mosquitoes) for 1 to 8 days. Noninoculated tankmates also became infected. The viremia profiles and multiple routes of infection suggest alligators may play an important role in WNV transmission in areas with high population densities of juvenile alligators. PMID:15663852

  10. Alligators as West Nile virus amplifiers.

    PubMed

    Klenk, Kaci; Snow, Jamie; Morgan, Katrina; Bowen, Richard; Stephens, Michael; Foster, Falicia; Gordy, Paul; Beckett, Susan; Komar, Nicholas; Gubler, Duane; Bunning, Michel

    2004-12-01

    Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >5.0 log10 PFU/mL (a threshold considered infectious for Culex quinquefasciatus mosquitoes) for 1 to 8 days. Noninoculated tankmates also became infected. The viremia profiles and multiple routes of infection suggest alligators may play an important role in WNV transmission in areas with high population densities of juvenile alligators.

  11. Preference index supported by motivation tests in Nile tilapia

    PubMed Central

    2017-01-01

    The identification of animal preferences is assumed to provide better rearing environments for the animals in question. Preference tests focus on the frequency of approaches or the time an animal spends in proximity to each item of the investigated resource during a multiple-choice trial. Recently, a preference index (PI) was proposed to differentiate animal preferences from momentary responses (Sci Rep, 2016, 6:28328, DOI: 10.1038/srep28328). This index also quantifies the degree of preference for each item. Each choice response is also weighted, with the most recent responses weighted more heavily, but the index includes the entire bank of tests, and thus represents a history-based approach. In this study, we compared this PI to motivation tests, which consider how much effort is expended to access a resource. We performed choice tests over 7 consecutive days for 34 Nile tilapia fish that presented with different colored compartments in each test. We first detected the preferred and non-preferred colors of each fish using the PI and then tested their motivation to reach these compartments. We found that fish preferences varied individually, but the results were consistent with the motivation profiles, as individual fish were more motivated (the number of touches made on transparent, hinged doors that prevented access to the resource) to access their preferred items. On average, most of the 34 fish avoided the color yellow and showed less motivation to reach yellow and red colors. The fish also exhibited greater motivation to access blue and green colors (the most preferred colors). These results corroborate the PI as a reliable tool for the identification of animal preferences. We recommend this index to animal keepers and researchers to identify an animal’s preferred conditions. PMID:28426689

  12. Polychlorinated Biphenyls Water Pollution along the River Nile, Egypt

    PubMed Central

    Megahed, Ayman Mohamed; Dahshan, Hesham; Abd-El-Kader, Mahdy A.; Abd-Elall, Amr Mohamed Mohamed; Elbana, Mariam Hassan; Nabawy, Ehab; Mahmoud, Hend A.

    2015-01-01

    Ten polychlorinated biphenyl (PCB) congeners were determined in water samples collected along the River Nile using gas chromatography-electron capture detector (GC-ECD). PCB concentrations ranged from 14 to 20 μg/L, which were higher than those reported in previous studies, indicating serious PCB pollution in the River Nile. PCB congener profiles varied depending on the sampling sties. PCB-138 was the predominant congener accounting for more than 18% of total PCBs. The composition of PCB congeners in the water revealed that highly chlorinated PCB technical mixtures such as Aroclor 1254 was the main PCB production historically used in Egypt. An increasing trend in PCB levels from the upper stream to the Nile estuaries was observed. The calculated flux of PCBs indicated that 6.8 tons of PCBs is dumped into the Mediterranean Sea each year from the River Nile. The hazard quotients and carcinogenic risk caused by PCB pollution in the River Nile were above the acceptable level indicating that PCBs in the River Nile water pose adverse health effects for all age groups. Our findings revealed that PCBs possess a serious risk to the Egyptian population that depends mainly on the River Nile as a source of water. Thus, stricter legislation and regulatory controls should be applied to reduce the risk of PCBs in Egypt. PMID:26798844

  13. Polychlorinated Biphenyls Water Pollution along the River Nile, Egypt.

    PubMed

    Megahed, Ayman Mohamed; Dahshan, Hesham; Abd-El-Kader, Mahdy A; Abd-Elall, Amr Mohamed Mohamed; Elbana, Mariam Hassan; Nabawy, Ehab; Mahmoud, Hend A

    2015-01-01

    Ten polychlorinated biphenyl (PCB) congeners were determined in water samples collected along the River Nile using gas chromatography-electron capture detector (GC-ECD). PCB concentrations ranged from 14 to 20 μg/L, which were higher than those reported in previous studies, indicating serious PCB pollution in the River Nile. PCB congener profiles varied depending on the sampling sties. PCB-138 was the predominant congener accounting for more than 18% of total PCBs. The composition of PCB congeners in the water revealed that highly chlorinated PCB technical mixtures such as Aroclor 1254 was the main PCB production historically used in Egypt. An increasing trend in PCB levels from the upper stream to the Nile estuaries was observed. The calculated flux of PCBs indicated that 6.8 tons of PCBs is dumped into the Mediterranean Sea each year from the River Nile. The hazard quotients and carcinogenic risk caused by PCB pollution in the River Nile were above the acceptable level indicating that PCBs in the River Nile water pose adverse health effects for all age groups. Our findings revealed that PCBs possess a serious risk to the Egyptian population that depends mainly on the River Nile as a source of water. Thus, stricter legislation and regulatory controls should be applied to reduce the risk of PCBs in Egypt.

  14. Nile Delta vegetation response to Holocene climate variability

    USGS Publications Warehouse

    Bernhardt, Christopher E.; Horton, Benjamin P.; Stanley, Jean-Daniel

    2012-01-01

    A 7000 yr palynologic record from Burullus Lagoon, Nile Delta, Egypt, is assessed to investigate changes in terrestrial vegetation in response to Nile flow. Previous studies in this region have shown that sea-level rise in the early to mid-Holocene, and markedly increased human land use during the past several centuries, altered vegetation in and around the lagoon. The pollen record from this study documents changes in delta vegetation that likely reflect variations in Nile flow. We suggest that Cyperaceae pollen is a sensitive marker of precipitation over the Nile headwaters and the resultant Nile flow. Decreases in Cyperaceae pollen, interpreted as a marker for diminished Nile flow, as well as the increase in relative abundance of microscopic charcoal, occurred at ca. 6000–5500, ca. 5000, ca. 4200, and ca. 3000 cal. yr B.P. (calibrated years before present). These correspond to extreme regional and global aridity events associated with a more southerly mean position of the Intertropical Convergence Zone. These changes, also recorded by other proxy studies, indicate that several marked regional drought events affected the Nile Delta region and impacted ancient Egyptian and Middle Eastern civilizations.

  15. In Vitro and In Vivo Blood-Brain Barrier Models to Study West Nile Virus Pathogenesis.

    PubMed

    Kumar, Mukesh; Nerurkar, Vivek R

    2016-01-01

    The blood-brain barrier (BBB), a specialized interface between the peripheral blood circulation and the central nervous system, specifically regulates molecular and cellular flux between the two. It plays a critical role in the maintenance of brain hemostasis. The BBB restricts the entry of pathogens into the brain, and thus its permeability is a critical factor that determines their central effects. Once the permeability of BBB is compromised, it has serious implications in the etiology of many brain pathologies including West Nile virus (WNV) disease. In this chapter, we describe protocols for preparation, maintenance, infection and permeability measurement of monolayer and bilayer in vitro BBB models to study WNV pathogenesis. We also describe Evans blue dye assay, a well-established method to test vascular permeability in vivo after WNV infection.

  16. Optimal operation of a multipurpose multireservoir system in the Eastern Nile River Basin

    NASA Astrophysics Data System (ADS)

    Goor, Q.; Halleux, C.; Mohamed, Y.; Tilmant, A.

    2010-07-01

    The upper Blue Nile River Basin in Ethiopia is a largely untapped resource despite its huge potential for hydropower generation and irrigated agriculture. Controversies exist as to whether the numerous infrastructural development projects that are on the drawing board in Ethiopia will generate positive or negative externalities downstream in Sudan and Egypt. This study attempts at 1) examining the (re-)operation of infrastructures, in particular the proposed reservoirs in Ethiopia and the High Aswan Dam and 2) assessing the economic benefits and costs associated with the storage infrastructures in Ethiopia and their spatial and temporal distribution. To achieve this, a basin-wide integrated hydro-economic model has been developed. The model integrates essential hydrologic, economic and institutional components of the river basin in order to explore both the hydrologic and economic consequences of various policy options and planned infrastructural projects. Unlike most of the deterministic economic-hydrologic models reported in the literature, a stochastic programming formulation has been adopted in order to: i) understand the effect of the hydrologic uncertainty on management decisions, ii) determine allocation policies that naturally hedge against the hydrological risk, and iii) assess the relevant risk indicators. The study reveals that the development of four mega dams in the upper part of the Blue Nile Basin would change the drawdown refill cycle of the High Aswan Dam. Should the operation of the reservoirs be coordinated, they would enable an average annual saving of at least 2.5 billion m3 through reduced evaporation losses from the Lake Nasser. Moreover, the new reservoirs (Karadobi, Beko-Abo, Mandaya and Border) in Ethiopia would have significant positive impacts on hydropower generation and irrigation in Ethiopia and Sudan: at the basin scale, the annual energy generation is boosted by 38.5 TWh amongst which 14.2 TWh due to storage. Moreover, the

  17. Optimal operation of a multipurpose multireservoir system in the Eastern Nile River Basin

    NASA Astrophysics Data System (ADS)

    Goor, Q.; Halleux, C.; Mohamed, Y.; Tilmant, A.

    2010-10-01

    The upper Blue Nile River Basin in Ethiopia is a largely untapped resource despite its huge potential for hydropower generation and irrigated agriculture. Controversies exist as to whether the numerous infrastructural development projects that are on the drawing board in Ethiopia will generate positive or negative externalities downstream in Sudan and Egypt. This study attempts at (1) examining the (re-)operation of infrastructures, in particular the proposed reservoirs in Ethiopia and the High Aswan Dam and (2) assessing the economic benefits and costs associated with the storage infrastructures in Ethiopia and their spatial and temporal distribution. To achieve this, a basin-wide integrated hydro-economic model has been developed. The model integrates essential hydrologic, economic and institutional components of the river basin in order to explore both the hydrologic and economic consequences of various policy options and planned infrastructural projects. Unlike most of the deterministic economic-hydrologic models reported in the literature, a stochastic programming formulation has been adopted in order to: (i) understand the effect of the hydrologic uncertainty on management decisions, (ii) determine allocation policies that naturally hedge against the hydrological risk, and (iii) assess the relevant risk indicators. The study reveals that the development of four mega dams in the upper part of the Blue Nile Basin would change the drawdown refill cycle of the High Aswan Dam. Should the operation of the reservoirs be coordinated, they would enable an average annual saving of at least 2.5 billion m3 through reduced evaporation losses from the Lake Nasser. Moreover, the new reservoirs (Karadobi, Beko-Abo, Mandaya and Border) in Ethiopia would have significant positive impacts on hydropower generation and irrigation in Ethiopia and Sudan: at the basin scale, the annual energy generation is boosted by 38.5 TWh amongst which 14.2 TWh due to storage. Moreover, the

  18. 12. VIEW OF NILES TREAD LATHE. Turning down tread on ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. VIEW OF NILES TREAD LATHE. Turning down tread on wheels. Wilbur Johnston, operator. - Juniata Shops, Erecting Shop & Machine Shop, East of Fourth Avenue, between Fourth & Fifth Streets, Altoona, Blair County, PA

  19. 11. VIEW OF NILES TREAD LATHE. Turning down tread on ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. VIEW OF NILES TREAD LATHE. Turning down tread on wheels. Wilbur Johnston, operator. - Juniata Shops, Erecting Shop & Machine Shop, East of Fourth Avenue, between Fourth & Fifth Streets, Altoona, Blair County, PA

  20. Cairo, Egypt/Nile River viewed from STS-66 Atlantis

    NASA Image and Video Library

    1994-11-14

    This close-up view of the intensively cultivated Nile River flood plain near Cairo presents a sharp color contrast to the virtually non-vegetated, sandy desert, located to the west of the vegetated area. Some rectangular cultivated field patterns, as well as circular center pivot irrigation patterns, can be observed northwest of the Nile River flood plain. The world famous Giza Pyramids are located near the center of this photography (see highly reflective sand surfaces).

  1. Conflicts of Shared Resources: A Case Study of River Nile

    DTIC Science & Technology

    2012-03-22

    as Lake Kivu. Rwanda joined the earlier Nile basin project, Hydromet , in 1967, with the support on the UNDP. 18 Although the country does not...operation Hydromet . In 1967, with the assistance of the United Nations Development Program (UNDP) and the World Meteorological Organization (WMO), Egypt...Kenya, Sudan, Tanzania and Uganda launched the Hydromet Survey project to regulate the water level of the Nile.”30 Rwanda joined later while Ethiopia

  2. Climate change enhances interannual variability of the Nile river flow

    NASA Astrophysics Data System (ADS)

    Siam, Mohamed S.; Eltahir, Elfatih A. B.

    2017-04-01

    The human population living in the Nile basin countries is projected to double by 2050, approaching one billion. The increase in water demand associated with this burgeoning population will put significant stress on the available water resources. Potential changes in the flow of the Nile River as a result of climate change may further strain this critical situation. Here, we present empirical evidence from observations and consistent projections from climate model simulations suggesting that the standard deviation describing interannual variability of total Nile flow could increase by 50% (+/-35%) (multi-model ensemble mean +/- 1 standard deviation) in the twenty-first century compared to the twentieth century. We attribute the relatively large change in interannual variability of the Nile flow to projected increases in future occurrences of El Niño and La Niña events and to observed teleconnection between the El Niño-Southern Oscillation and Nile River flow. Adequacy of current water storage capacity and plans for additional storage capacity in the basin will need to be re-evaluated given the projected enhancement of interannual variability in the future flow of the Nile river.

  3. STS-56 Earth observation of the northeastern Nile Delta

    NASA Image and Video Library

    1993-04-17

    STS-56 Earth observation of the northeastern Nile Delta was photographed from the Earth-orbiting Discovery, Orbiter Vehicle (OV) 103. The branch of the Nile featured in the frame is Daimietta. The Suez Canal marks the boundary of the Nile Delta agriculture and the Sinai Desert to the right. Lake Masada, the dark waterlogged area to the west (left) of Port Said is becoming more saline as the Aswan Dam has reduced sediment downstream. This sediment reduction, according to NASA scientists studying the STS-56 photography, has resulted in increased coastal erosion and the intrusion of a salt-water lens to the ground water, particularly in the northeastern portions of the delta. Center pivot irrigation fields are located along either side of the Ramses Canal, which connects the Daimietta Nile with Great Bitter Lake. This canal has been re-dug three or four times in the past 3,000 years. Historians note that the canal's most famous use was as the departure point of the fleet of Pharaoh Necho. The fleet circumnavigated Africa clockwise from the head of the Red Sea to the Mediterranean coast of the Nile (probably the Rosetta Nile) in a three-year voyage circa 660 BC.

  4. Infectious disease. The enigma of West Nile. .

    PubMed

    Enserink, M

    2000-11-24

    Fifteen months after the 1999 outbreak of West Nile virus in New York City, which sickened 62 mostly elderly people and killed seven, scientists are still hard pressed to predict how abundant the virus will eventually become or how serious a public health threat it will pose. This summer, the human toll has been relatively mild, with just 18 cases and one death. But the virus has been found in more than 60 bird species and about a dozen mammals; in a little more than a year, it has spread to 11 states along the East Coast and the District of Columbia. And with no natural barriers to stop it, scientists can safely say that it will keep spreading.

  5. West Nile Virus Economic Impact, Louisiana, 2002

    PubMed Central

    Meltzer, Martin I.; Ratard, Raoult; Billah, Kaafee; Molinari, Noelle A.; Roy, Kakoli; Scott, R. Douglas; Petersen, Lyle R.

    2004-01-01

    West Nile virus (WNV) is transmitted by mosquitoes and can cause illness in humans ranging from mild fever to encephalitis. In 2002, a total of 4,156 WNV cases were reported in the United States; 329 were in Louisiana. To estimate the economic impact of the 2002 WNV epidemic in Louisiana, we collected data from hospitals, a patient questionnaire, and public offices. Hospital charges were converted to economic costs by using Medicare cost-to-charge ratios. The estimated cost of the Louisiana epidemic was $20.1 million from June 2002 to February 2003, including a $10.9 million cost of illness ($4.4 million medical and $6.5 million nonmedical costs) and a $9.2 million cost of public health response. These data indicate a substantial short-term cost of the WNV disease epidemic in Louisiana. PMID:15504258

  6. West Nile virus infection of birds, Mexico.

    PubMed

    Guerrero-Sánchez, Sergio; Cuevas-Romero, Sandra; Nemeth, Nicole M; Trujillo-Olivera, María Teresa Jesús; Worwa, Gabriella; Dupuis, Alan; Brault, Aaron C; Kramer, Laura D; Komar, Nicholas; Estrada-Franco, José Guillermo

    2011-12-01

    West Nile virus (WNV) has caused disease in humans, equids, and birds at lower frequency in Mexico than in the United States. We hypothesized that the seemingly reduced virulence in Mexico was caused by attenuation of the Tabasco strain from southeastern Mexico, resulting in lower viremia than that caused by the Tecate strain from the more northern location of Baja California. During 2006-2008, we tested this hypothesis in candidate avian amplifying hosts: domestic chickens, rock pigeons, house sparrows, great-tailed grackles, and clay-colored thrushes. Only great-tailed grackles and house sparrows were competent amplifying hosts for both strains, and deaths occurred in each species. Tecate strain viremia levels were higher for thrushes. Both strains produced low-level viremia in pigeons and chickens. Our results suggest that certain avian hosts within Mexico are competent for efficient amplification of both northern and southern WNV strains and that both strains likely contribute to bird deaths.

  7. Blue Ocean Thinking

    ERIC Educational Resources Information Center

    Orem, Donna

    2016-01-01

    This article describes a concept called the "blue ocean thinking strategy," developed by W. Chan Kim and Renée Mauborgne, professors at INSEAD, an international graduate school of business in France. The "blue ocean" thinking strategy considers opportunities to create new markets for services, rather than focusing solely on…

  8. Introducing the Blues.

    ERIC Educational Resources Information Center

    Sinclair, Bryan

    2000-01-01

    Discusses the history of the blues and presents a list of resources that are designed to introduce the blues, both as a feeling and as an influential part of American music and culture. Includes picture books and nonfiction for young readers, nonfiction for older readers, Web sites, and compact disks. (LRW)

  9. Blue Ocean Thinking

    ERIC Educational Resources Information Center

    Orem, Donna

    2016-01-01

    This article describes a concept called the "blue ocean thinking strategy," developed by W. Chan Kim and Renée Mauborgne, professors at INSEAD, an international graduate school of business in France. The "blue ocean" thinking strategy considers opportunities to create new markets for services, rather than focusing solely on…

  10. Templated blue phases.

    PubMed

    Ravnik, Miha; Fukuda, Jun-ichi

    2015-11-21

    Cholesteric blue phases of a chiral liquid crystal are interesting examples of self-organised three-dimensional nanostructures formed by soft matter. Recently it was demonstrated that a polymer matrix introduced by photopolymerization inside a bulk blue phase not only stabilises the host blue phase significantly, but also serves as a template for blue phase ordering. We show with numerical modelling that the transfer of the orientational order of the blue phase to the surfaces of the polymer matrix, together with the resulting surface anchoring, can account for the templating behaviour of the polymer matrix inducing the blue phase ordering of an achiral nematic liquid crystal. Furthermore, tailoring the anchoring conditions of the polymer matrix surfaces can bring about orientational ordering different from those of bulk blue phases, including an intertwined complex of the polymer matrix and topological line defects of orientational order. Optical Kerr response of templated blue phases is explored, finding large Kerr constants in the range of K = 2-10 × 10(-9) m V(-2) and notable dependence on the surface anchoring strength. More generally, the presented numerical approach is aimed to clarify the role and actions of templating polymer matrices in complex chiral nematic fluids, and further to help design novel template-based materials from chiral liquid crystals.

  11. Blue Willow Story Plates

    ERIC Educational Resources Information Center

    Fontes, Kris

    2009-01-01

    In the December 1997 issue of "SchoolArts" is a lesson titled "Blue Willow Story Plates" by Susan Striker. In this article, the author shares how she used this lesson with her middle-school students many times over the years. Here, she describes a Blue Willow plate painting project that her students made.

  12. Blue Willow Story Plates

    ERIC Educational Resources Information Center

    Fontes, Kris

    2009-01-01

    In the December 1997 issue of "SchoolArts" is a lesson titled "Blue Willow Story Plates" by Susan Striker. In this article, the author shares how she used this lesson with her middle-school students many times over the years. Here, she describes a Blue Willow plate painting project that her students made.

  13. List 47: blue honeysuckle

    USDA-ARS?s Scientific Manuscript database

    This summary presents the descriptions of a newly released blue honeysuckle (Lonicera cerulea L.) cultivar for the List of New Fruit and Nut Cultivars. This blue honeysuckle cultivar was released in Canada in 2012 and has pending Plant Breeder’s Rights Certification with Agriculture Canada. The cult...

  14. After Stroke, 'Blue' Light May Help Beat the Blues

    MedlinePlus

    ... Light May Help Beat the Blues Akin to sunlight, it could ward off depression during rehab, study ... facility used "blue" light in its lighting system. Sunlight is humans' largest source of blue-spectrum light, ...

  15. From blue jeans to blue genes.

    PubMed

    Boon, Laurence M; Vikkula, Miikka

    2009-03-01

    Cutaneous venous anomalies are common. They are blue and vary in size, number, and location and account for most consultations at specialized interdisciplinary clinics for vascular anomalies. Venous lesions are clinically important because they cause pain, dysfunction, destruction of adjacent tissues, and esthetic concern. Only resection and sclerotherapy are helpful, although not always curative. Understanding etiopathogenesis could help design animal models and develop novel therapeutic approaches. John B. Mulliken, MD, envisioned a project to uncover the genetic basis of an inherited form of venous malformation in a large New England family. Recruitment of 2 young fellows resulted in a collaborative project that unraveled the searched-for gene and its mutation. This was an opening for a new era in vascular anomalies. Two blue genes' mutations were discovered, which account for most, if not all, of the inherited forms of venous anomalies, but other genes as well, for rheologically diverse lesions. Differential diagnosis and management has improved, and animal models are being made. This was achieved through the help of Dr Mulliken, who inspired 2 young investigators in blue jeans to find 2 blue genes.

  16. FROM BLUE JEANS TO BLUE GENES

    PubMed Central

    Boon, Laurence M.; Vikkula, Miikka

    2010-01-01

    Cutaneous venous anomalies are common. They are blue in color and vary in size, number and location, and account for the majority of consultations at specialized interdisciplinary clinics for vascular anomalies. Venous lesions are clinically important as they cause pain, dysfunction, destruction of adjacent tissues and esthetic concern. Only resection and sclerotherapy are helpful, although not always curative. Understanding etiopathogenesis could help design animal models and develop novel therapeutic approaches. Dr Mulliken envisioned a project to uncover the genetic basis of an inherited form of venous malformation in a large New England family. Recruitment of two young fellows resulted in a collaborative project that unraveled the searched-for-gene and its mutation. This was an opening for a new era in the field of vascular anomalies. Two blue genes’ mutations were discovered, which account for the majority, if not all, of the inherited forms of venous anomalies, but other genes as well, for rheologically diverse lesions. Differential diagnosis and management has improved, and animal models are being made. This was achieved thanks to Dr Mulliken, who inspired two young investigators in blue jeans to find two blue genes. PMID:19190503

  17. Rapid antigen-capture assay to detect West Nile virus in dead corvids.

    PubMed

    Lindsay, Robbin; Barker, Ian k; Nayar, Gopi; Drebot, Michael; Calvin, Sharon; Scammell, Cherie; Sachvie, Cheril; Fleur, Tracy Scammell-La Fleur; Dibernardo, Antonia; Andonova, Maya; Artsob, Harvey

    2003-11-01

    The utility of the VecTest antigen-capture assay to detect West Nile virus (WNV) in field-collected dead corvids was evaluated in Manitoba and Ontario, Canada, in 2001 and 2002. Swabs were taken from the oropharynx, cloaca, or both of 109 American Crows, 31 Blue Jays, 6 Common Ravens, and 4 Black-billed Magpies from Manitoba, and 255 American Crows and 28 Blue Jays from Ontario. The sensitivity and specificity of the antigen-capture assay were greatest for samples from American Crows; oropharyngeal swabs were more sensitive than cloacal swabs, and interlaboratory variation in the results was minimal. The sensitivity and specificity of the VecTest using oropharyngeal swabs from crows were 83.9% and 93.6%, respectively, for Manitoba samples and 83.3% and 95.8%, respectively, for Ontario birds. The VecTest antigen-capture assay on oropharyngeal secretions from crows is a reliable and rapid diagnostic test that appears suitable for incorporation into a WNV surveillance program.

  18. Rapid Antigen-Capture Assay To Detect West Nile Virus in Dead Corvids

    PubMed Central

    Barker, Ian; Nayar, Gopi; Drebot, Michael; Calvin, Sharon; Scammell, Cherie; Sachvie, Cheryl; La Fleur, Tracy Scammell; Dibernardo, Antonia; Andonova, Maya; Artsob, Harvey

    2003-01-01

    The utility of the VecTest antigen-capture assay to detect West Nile virus (WNV) in field-collected dead corvids was evaluated in Manitoba and Ontario, Canada, in 2001 and 2002. Swabs were taken from the oropharynx, cloaca, or both of 109 American Crows, 31 Blue Jays, 6 Common Ravens, and 4 Black-billed Magpies from Manitoba, and 255 American Crows and 28 Blue Jays from Ontario. The sensitivity and specificity of the antigen-capture assay were greatest for samples from American Crows; oropharyngeal swabs were more sensitive than cloacal swabs, and interlaboratory variation in the results was minimal. The sensitivity and specificity of the VecTest using oropharyngeal swabs from crows were 83.9% and 93.6%, respectively, for Manitoba samples and 83.3% and 95.8%, respectively, for Ontario birds. The VecTest antigen-capture assay on oropharyngeal secretions from crows is a reliable and rapid diagnostic test that appears suitable for incorporation into a WNV surveillance program. PMID:14718083

  19. 78 FR 16505 - Prospective Grant of Exclusive License: Chimeric West Nile/Dengue Viruses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ...: Chimeric West Nile/Dengue Viruses AGENCY: Centers for Disease Control and Prevention (CDC), Department of... Application 61/049,342, filed 4/30/2008, entitled ``Engineered, Chimeric West Nile/Dengue Viruses;'' PCT..., filed 10/29/2010, entitled ``Chimeric West Nile/Dengue Viruses;'' and all related continuing and foreign...

  20. Blue ocean strategy.

    PubMed

    Kim, W Chan; Mauborgne, Renée

    2004-10-01

    Despite a long-term decline in the circus industry, Cirque du Soleil profitably increased revenue 22-fold over the last ten years by reinventing the circus. Rather than competing within the confines of the existing industry or trying to steal customers from rivals, Cirque developed uncontested market space that made the competition irrelevant. Cirque created what the authors call a blue ocean, a previously unknown market space. In blue oceans, demand is created rather than fought over. There is ample opportunity for growth that is both profitable and rapid. In red oceans--that is, in all the industries already existing--companies compete by grabbing for a greater share of limited demand. As the market space gets more crowded, prospects for profits and growth decline. Products turn into commodities, and increasing competition turns the water bloody. There are two ways to create blue oceans. One is to launch completely new industries, as eBay did with online auctions. But it's much more common for a blue ocean to be created from within a red ocean when a company expands the boundaries of an existing industry. In studying more than 150 blue ocean creations in over 30 industries, the authors observed that the traditional units of strategic analysis--company and industry--are of limited use in explaining how and why blue oceans are created. The most appropriate unit of analysis is the strategic move, the set of managerial actions and decisions involved in making a major market-creating business offering. Creating blue oceans builds brands. So powerful is blue ocean strategy, in fact, that a blue ocean strategic move can create brand equity that lasts for decades.

  1. West Nile Virus Ecology in a Tropical Ecosystem in Guatemala

    PubMed Central

    Morales-Betoulle, Maria E.; Komar, Nicholas; Panella, Nicholas A.; Alvarez, Danilo; López, María R.; Betoulle, Jean-Luc; Sosa, Silvia M.; Müller, María L.; Kilpatrick, A. Marm; Lanciotti, Robert S.; Johnson, Barbara W.; Powers, Ann M.; Cordón-Rosales, Celia

    2013-01-01

    West Nile virus ecology has yet to be rigorously investigated in the Caribbean Basin. We identified a transmission focus in Puerto Barrios, Guatemala, and established systematic monitoring of avian abundance and infection, seroconversions in domestic poultry, and viral infections in mosquitoes. West Nile virus transmission was detected annually between May and October from 2005 to 2008. High temperature and low rainfall enhanced the probability of chicken seroconversions, which occurred in both urban and rural sites. West Nile virus was isolated from Culex quinquefasciatus and to a lesser extent, from Culex mollis/Culex inflictus, but not from the most abundant Culex mosquito, Culex nigripalpus. A calculation that combined avian abundance, seroprevalence, and vertebrate reservoir competence suggested that great-tailed grackle (Quiscalus mexicanus) is the major amplifying host in this ecosystem. West Nile virus transmission reached moderate levels in sentinel chickens during 2007, but less than that observed during outbreaks of human disease attributed to West Nile virus in the United States. PMID:23149586

  2. Safety of West Nile Virus vaccines in sandhill crane chicks

    USGS Publications Warehouse

    Olsen, G.H.; Miller, K.J.; Docherty, D.E.; Bochsler, V.S.; Folk, Martin J.; Nesbitt, Stephen A.

    2008-01-01

    West Nile virus arrived in North America in 1999 and has spread across the continent in the ensuing years. The virus has proven deadly to a variety of native avian species including sandhill cranes (Grus canadensis). In order to provide safe and efficacious protection for captive and released populations of whooping cranes (G. americana), we have conducted a series of four research projects. The last of these was a study of the effects of two different West Nile virus vaccines on young Florida sandhill crane (G. c. pratensis) chicks and subsequent challenge with the virus. We found that vaccinating crane chicks as early as day 7 post-hatch caused no adverse reactions or noticeable morbidity. We tested both a commercial equine vaccine West Nile - Innovator (Fort Dodge Laboratories, Fort Dodge, Iowa) and a new recombinant DNA vaccine (Centers for Disease Control). We had a 33% mortality in control chicks (n =6) from West Nile virus infection, versus 0% mortality in two groups of vaccinated chicks (n = 12), indicating the two vaccines tested were not only safe but effective in preventing West Nile virus.

  3. [West Nile virus transmission risk in the Czech Republic].

    PubMed

    Vlčková, J; Rupeš, V; Horáková, D; Kollárová, H; Holý, O

    2015-06-01

    West Nile Virus (WNV) belongs to the family Flaviviridae. It is transmitted to humans by mosquitoes, capable of sucking blood on birds and mammals, most often by mosquitoes of the genus Culex. In humans, the virus was first identified in 1937 in the West Nile region, Uganda, Africa. Later, the virus spread and caused more or less severe epidemics of West Nile fever in North Africa, Europe, Asia, and North and South America. During the last two decades, WNV has been on the rise and is currently ranked as one of the most prevalent arboviruses in the world. In humans, WNV infection mostly occurs as asymptomatic, but may have a more severe or even fatal course in older and weakened patients. Humans may become infected not only by mosquitoes that acquire the virus from infected birds, but also through a blood transfusion, organ transplant, breast milk and transplacental transmission, or contact with infected animals, their blood, and tissues. The first autochthonous human case of West Nile fever in the Czech Republic was reported from South Moravia in 1997. In 2013, another case of West Nile fever emerged in this country, in the Ostrava area. The issue of WNV has recently been studied from many different perspectives, as evidenced by many original and review papers. This article briefly reviews the essential knowledge about this virus and its spread.

  4. Structure-function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers.

    PubMed

    Vecchio, Daniela; Bhayana, Brijesh; Huang, Liyi; Carrasco, Elisa; Evans, Conor L; Hamblin, Michael R

    2014-03-21

    The benzophenothiazinium dye EtNBS has previously been tested as a photosensitizer to mediate photodynamic therapy (PDT). It has been employed to kill cancer cells and microbial cells in vitro and to treat tumors and infections in vivo. We synthesized a panel of derivatives substituted at the 1-position of the benzene ring with electron donating or electron withdrawing groups (amino, acetamido and nitro) and tested their production of reactive oxygen species (ROS) and light-mediated killing of two species of Gram-positive and two species of Gram-negative bacteria. All three compounds showed lower fluorescence, lower yield of ROS and less microbial killing than parent EtNBS, while the order of activity (nitro > amino > acetamido) showed that an electron withdrawing substituent was better than electron donating. To test the hypothesis that 1-substitution distorts the planar structure of the conjugated rings we compared two compounds substituted with N-ethylpropylsulfonamido either at the 1-position or at the 4-position. The 4-isomer was significantly more photoactive than the 1-isomer. We also prepared an EtNBS derivative with a guanidinium group attached to the 5-amino group. This compound had high activity against Gram-negative bacteria due to the extra positive charge. Cellular uptake of the compounds by the four bacterial species was also measured and broadly correlated with activity. These results provided three separate pieces of structure-activity relationship data for antimicrobial photosensitizers based on the EtNBS backbone. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  5. Mongolian blue spots

    MedlinePlus

    ... bruises. This can raise a question about possible child abuse. It is important to recognize that Mongolian blue ... Elsevier Saunders; 2011:chap 11. Read More Benign Child abuse - physical Rashes Review Date 4/14/2015 Updated ...

  6. Pale Blue Orb

    NASA Image and Video Library

    2006-09-19

    NASA Cassini casts powerful eyes on our home planet, and captures Earth, a pale blue orb, and a faint suggestion of our moon, among the glories of the Saturn system in this image taken Sept. 15, 2006.

  7. Blue Ribbon Panel Report

    Cancer.gov

    An NCI Cancer Currents blog by the NCI acting director thanking the cancer community for contributing to the Cancer Moonshot Blue Ribbon Panel report, which was presented to the National Cancer Advisory Board on September 7.

  8. Blue-green algae

    MedlinePlus

    ... conditions, cancer, fatty liver disease, hepatitis C, and arsenic poisoning. Blue-green algae are applied inside the mouth ... people with insulin resistance due to HIV medication. Arsenic poisoning. Early research shows that taking 250 mg of ...

  9. Village Blue Webinar

    EPA Pesticide Factsheets

    The Village Blue research project provides real-time water quality monitoring data to the Baltimore community and increase public awareness about local water quality in Baltimore Harbor and the Chesapeake Bay.

  10. Mongolian blue spots (image)

    MedlinePlus

    Mongolian blue spots are flat bluish- to bluish-gray skin markings commonly appearing at birth or shortly ... back and also can appear on the shoulders. Mongolian spots are benign and are not associated with ...

  11. Time Series Models Adoptable for Forecasting Nile Floods and Ethiopian Rainfalls.

    NASA Astrophysics Data System (ADS)

    El-Fandy, M. G.; Taiel, S. M. M.; Ashour, Z. H.

    1994-01-01

    Long-term rainfall forecasting is used in making economic and agricultural decisions in many countries. It may also be a tool in minimizing the devastation resulting from recurrent droughts. To be able to forecast the total annual rainfall or the levels of seasonal floods, a class of models has first been chosen. The model parameters have then been estimated with an appropriate parameter estimation algorithm. Finally, diagnostic tests have been performed to verify the adequacy of the model. These are the general principles of system identification, which is the most crucial part of the forecasting procedure. In this paper several sets of data have been studied using different statistical procedures. The examined data include a historical 835-year record representing the levels of the seasonal Nile floods in Cairo, Egypt, during the period A.D. 622-1457. These readings were originally carried out by the Arabsto a great degree of accuracy in order to be used in estimating yearly taxes or Zacat (islamic duties). The observations also comprise recent total annual rainfall data over Addis Ababa (Ethiopia) (1907-1984), the total annual discharges of Ethiopian rivers (including the river Sobat discharges at Hillet Doleib, Blue Nile discharge at Roseris, river Dinder, river Rahar, and river Atbara), equatorial lake plateau supply as contributed at Aswan during the period 1912-1982, and the total annual discharges at Aswan during the period 1871-1982. Periodograms have been used to uncover possible peridodicities. Trends of rainfall and discharges of some rivers of east and central Africa have been also estimated.Using the first half of the available record, two autoregressive integrated moving average (ARIMA) time series models have been identified, one for the levels of the seasonal Nile floods in Cairo, the second to model the annual rainfall over Ethiopia. The time series models have been applied in 1-year-ahead forecasting to the other hall of the available record and

  12. STS-57 Earth observation of the Eastern Mediterranean, Nile River, Asia Minor

    NASA Image and Video Library

    1993-07-01

    STS057-73-075 (21 June-1 July 1993) --- Eastern Mediterranean from an unusually high vantage point over the Nile River, this north-looking view shows not only the eastern Mediterranean but also the entire landmass of Asia Minor, with the Black Sea dimly visible at the horizon. Many of the Greek islands can be seen in the Aegean Sea (top left), off the coast of Asia Minor. Cyprus is visible under atmospheric dust in the northeast corner of the Mediterranean. The dust cloud covers the east end of the Mediterranean, its western edge demarcated by a line that cuts the center of the Nile Delta. This dust cloud originated far to the west, in Algeria, and moved northeast over Sicily, southern Italy, and Greece. Part of the cloud then moved on over the Black Sea, but another part swerved southward back towards Egypt. A gyre of clouds in the southeast corner of the Mediterranean indicates a complementary counterclockwise (cyclonic) circulation of air. The Euphrates River appears as a thin green line (upper right) in the yellow Syrian Desert just south of the blue-green mountains of Turkey. The Dead Sea (lower right) lies in a rift valley which extends north into Turkey and south thousands of miles down the Gulf of Aqaba, the Red Sea, and on through East Africa. The straight international boundary between Israel and Egypt (where the coastline angles) is particularly clear in this view, marked by the thicker vegetation on the Israeli side of the border. The green delta of the Nile River appears in the foreground, with the great conurbation of Cairo seen as a gray area at the apex of the triangle. Most of Egypt's 52 million inhabitants live in the delta. On the east side of the delta, the Suez Canal is visible. On the western corner of the delta lies the ancient city of Alexandria, beside the orange and white salt pans. The World War II battlesite El Alamein lies on the coast.

  13. [West Nile virus: a reality in Mexico].

    PubMed

    Téllez, Ildefonso; Calderón, Oscar; Franco-Paredes, Carlos; del Río, Carlos

    2006-01-01

    West Nile virus (WNV) is a RNA virus of the Flaviridae, genus flavivirus family. It is a neuropathogenic virus causing disease in birds, horses and humans. WNVis transmitted by the vector mosquito Culex sp. The virus life 's cycle includes mosquitoes as vectors and birds as natural hosts. Humans are accidental hosts. Since the introduction of the Epidemiological Surveillance Program at the Ministry ofHealth. we have documented 90 positive test results among birds out of 1,223 cases studied in Mexico as of September IS. 2005. The incubation period in humans after a mosquito bite ranges from 3 to 14 days. Disease is characterized by early onset fever, general malaise, decreased appetite, nausea, vomiting, headaches, myalgias, enlarged lymph nodes andrash. Neurological manifestations include encephalitis andflaccid paralysis, which are present in less than 1% of subjects infected with WNV. Older patients display more adverse outcomes including death. The diagnosis is made by the determination of specific IgM and JgG antibodies in serum and/or cerebrospinal fluid. There is no antiviral treatment to date against WNV but interferon ?2b, and WNVspec4ic-immunoglobulin have been used Prevention is therefore the key to control the infection.

  14. Host heterogeneity dominates West Nile virus transmission

    PubMed Central

    Marm Kilpatrick, A; Daszak, Peter; Jones, Matthew J; Marra, Peter P; Kramer, Laura D

    2006-01-01

    Heterogeneity in host populations and communities can have large effects on the transmission and control of a pathogen. In extreme cases, a few individuals give rise to the majority of secondary infections, which have been termed super spreading events. Here, we show that transmission of West Nile virus (WNV) is dominated by extreme heterogeneity in the host community, resulting in highly inflated reproductive ratios. A single relatively uncommon avian species, American robin (Turdus migratorius), appeared to be responsible for the majority of WNV-infectious mosquitoes and acted as the species equivalent of a super spreader for this multi-host pathogen. Crows were also highly preferred by mosquitoes at some sites, while house sparrows were significantly avoided. Nonetheless, due to their relative rarity, corvids (crows and jays) were relatively unimportant in WNV amplification. These results challenge current beliefs about the role of certain avian species in WNV amplification and demonstrate the importance of determining contact rates between vectors and host species to understand pathogen transmission dynamics. PMID:16928635

  15. Nonviremic transmission of West Nile virus

    PubMed Central

    Higgs, Stephen; Schneider, Bradley S.; Vanlandingham, Dana L.; Klingler, Kimberly A.; Gould, Ernest A.

    2005-01-01

    West Nile virus (WNV) is now the predominant circulating arthropod-borne virus in the United States with >15,000 human cases and >600 fatalities since 1999. Conventionally, mosquitoes become infected when feeding on viremic birds and subsequently transmit the virus to susceptible hosts. Here, we demonstrate nonviremic transmission of WNV between cofeeding mosquitoes. Donor, Culex pipiens quinquefasciatus mosquitoes infected with WNV were fed simultaneously with uninfected “recipient” mosquitoes on naïve mice. At all times, donor and recipient mosquitoes were housed in separate sealed containers, precluding the possibility of mixing. Recipients became infected in all five trials, with infection rates as high as 5.8% and no detectable viremia in the hosts. Remarkably, a 2.3% infection rate was observed when 87 uninfected mosquitoes fed adjacent to a single infected mosquito. This phenomenon could potentially enhance virus survival, transmission, and dispersion and obviate the requirement for viremia. All vertebrates, including immune and insusceptible animals, might therefore facilitate mosquito infection. Our findings question the status of dead-end hosts in the WNV transmission cycle and may partly explain the success with which WNV established and rapidly dispersed throughout North America. PMID:15951417

  16. West Nile viral infection of equids

    PubMed Central

    Angenvoort, J.; Brault, A.C.; Bowen, R.A.; Groschup, M.H.

    2015-01-01

    West Nile virus (WNV) is a flavivirus transmitted between certain species of birds and mosquito vectors. Tangential infections of equids and subsequent equine epizootics have occurred historically. Although the attack rate has been estimated to be below 10%, mortality rates can approach 50% in horses that present clinical disease. Symptoms are most commonly presenting in the form of encephalitis with ataxia as well as limb weakness, recumbency and muscle fasciculation. The most effective strategy for prevention of equine disease is proper vaccination with one of the numerous commercially available vaccines available in North America or the European Union. Recently, WNV has been increasingly associated with equine epizootics resulting from novel non-lineage-1a viruses in expanding geographic areas. However, specific experimental data on the virulence of these novel virus strains is lacking and questions remain as to the etiology of the expanded epizootics: whether it be a function of inherent virulence or ecological and/or climactic factors that could precipitate the altered epidemiological patterns observed. PMID:24035480

  17. The first reported case of West Nile encephalitis in Korea.

    PubMed

    Hwang, Jihye; Ryu, Ho-Sung; Kim, Hyunjin; Lee, Sang-Ahm

    2015-03-01

    West Nile encephalitis was first identified in 1937, but until now, it was never diagnosed in Korea. A 58-yr-old Korean man was admitted with headache and cognitive dysfunction. The patient had been on a business trip in Guinea. Cerebrospinal fluid (CSF) showed pleocytosis. The patient complained of both leg weakness,and arachnoiditis and myelitis were observed on lumbar magnetic resonance imaging (MRI). A specific neutralizing antibody for West Nile virus was positive in serum. After a treatment with interferon-α 3mu, follow up CSF findings recovered completely after 3 months later. The first case of West Nile encephalitis in Korea was imported from Guinea, and was cured successfully.

  18. Use of Network Modeling Tools in the Nile System Design

    NASA Astrophysics Data System (ADS)

    Avery, Paul

    I discuss the relevance of network modeling tools to high energy physics experiments, particularly for understanding data flows and identifying possible bottlenecks during data analysis. The Nile collaboration is using these tools to model a fault-tolerant computing system distributed over geographically dispersed sites. I summarize Nile's evaluation of three commericial tools and our initial experience with OpNet Modeler from Mil3, Inc. These tools seem to offer an effective way of quantifying data movements from online acquisition to physics analysis, including how they are affected by storage mechanisms, distribution, and the characteristics of local and wide area networks.

  19. A rapid-screening approach to detect and quantify microplastics based on fluorescent tagging with Nile Red

    PubMed Central

    Maes, Thomas; Jessop, Rebecca; Wellner, Nikolaus; Haupt, Karsten; Mayes, Andrew G.

    2017-01-01

    A new approach is presented for analysis of microplastics in environmental samples, based on selective fluorescent staining using Nile Red (NR), followed by density-based extraction and filtration. The dye adsorbs onto plastic surfaces and renders them fluorescent when irradiated with blue light. Fluorescence emission is detected using simple photography through an orange filter. Image-analysis allows fluorescent particles to be identified and counted. Magnified images can be recorded and tiled to cover the whole filter area, allowing particles down to a few micrometres to be detected. The solvatochromic nature of Nile Red also offers the possibility of plastic categorisation based on surface polarity characteristics of identified particles. This article details the development of this staining method and its initial cross-validation by comparison with infrared (IR) microscopy. Microplastics of different sizes could be detected and counted in marine sediment samples. The fluorescence staining identified the same particles as those found by scanning a filter area with IR-microscopy. PMID:28300146

  20. Orbital forcing of glacial/interglacial variations in chemical weathering within the White Nile basin: stable-isotope and biomarker evidence from Lakes Victoria and Edward

    NASA Astrophysics Data System (ADS)

    Cockerton, Helen E.; Alayne Street-Perrott, F.; Barker, Philip A.; Leng, Melanie J.; Sloane, Hilary J.; Horstwood, Matthew S. A.; Snelling, Andrea

    2014-05-01

    The continental Si cycle on Quaternary time scales has been largely neglected. Emphasis has been placed on long-term geochemical processes of silicate-rock weathering and the resulting drawdown of atmospheric CO2, rather than on shorter-term biogenic processes occurring along the land-ocean continuum. Si-accumulating plants (notably tropical rainforest hardwoods, savanna and wetland grasses, and Papyrus) and aquatic organisms (such as diatoms and sponges in lakes, rivers and swamps) have the potential to take up, store and recycle significant amounts of Si, thereby modifying the riverine flux of Si to the oceans, the productivity of siliceous marine organisms and the rate of atmospheric CO2 drawdown on an orbital time scale. The main aim of this study was to investigate spatial and temporal patterns of Si cycling along the Nile system during the last 20ka BP. Utilising sediment cores from Lakes Victoria and Edward, coupled measurements of stable Si and O isotopes on cleaned diatom separates were employed to reconstruct millennial-scale variations in biotic Si cycling and palaeohydrology, respectively. Abundance ratios of lipid biomarkers (n-alkanes) were used to track major changes in terrestrial and aquatic ecosystems. The results have been interpreted in the light of multi-isotope analyses (2H,18O,30Si) of modern water samples collected along the courses of the modern White and Blue Niles during both wet- and dry-season conditions. During drier intervals (the Last Glacial Maximum and the late Holocene: high 18Odiatom), Si cycling was greatly reduced. Diminished vegetation cover, reduced biotic rock weathering, a declining soil stock of amorphous silica (ASi) and decreased runoff resulted in reduced dissolved silica (DSi) supply to the lakes in relation to aquatic demand (high 30Sidiatom). In contrast, enhanced monsoon rainfall (low 18Odiatom) during the early to mid-Holocene promoted a substantial increase in terrestrial biomass within the White Nile headwaters

  1. Response of the Nile and its catchment to millennial-scale climatic change since the LGM from Sr isotopes and major elements of East Mediterranean sediments

    NASA Astrophysics Data System (ADS)

    Box, M. R.; Krom, M. D.; Cliff, R. A.; Bar-Matthews, M.; Almogi-Labin, A.; Ayalon, A.; Paterne, M.

    2011-02-01

    Changes in 87Sr/ 86Sr and major element geochemistry, from two sediment cores (9509 and 9501) in the Eastern Mediterranean (EM), were used to resolve changes in sediment provenance and, hence, determine climate changes in the Nile catchment and Eastern Sahara desert over the past 25 ka. The sediment was described by a three end-member system comprising Blue Nile (BN; 87Sr/ 86Sr = 0.7506; Sr = 210 ppm), White Nile (WN; 87Sr/ 86Sr = 0.7094; Sr = 72.5 ppm) and Saharan dust (SD; 87Sr/ 86Sr = 0.7183; Sr = 99 ppm). The sedimentary record of these cores represents the suspended load carried down the Nile river and discharged into the S.E. Levantine basin and thus records palaeoclimatically controlled changes in erosion and transport in the catchment. During arid periods (0-5 ka BP) and prior to 11 ka BP, fluxes of BN sediment at 9509 (˜6 g/cm 2/yr & 10-12 g/cm 2/yr, respectively) were greater than during the peak of the African Humid Period (AHP) from 5 to 11 ka BP (<2 g/cm 2/yr); this latter period witnessed the deposition of the youngest organic-rich sediment, termed sapropel (S-1), in the EM basin. By contrast the flux of WN increased during the AHP from ˜5 g/cm 2/yr at ˜13 ka BP to >15 g/cm 2/yr. In the Ethiopian Highlands (BN catchment) increases in the amount and duration of the monsoon during the AHP caused more vegetation to grow resulting in less soil erosion. In the WN catchment increased rainfall caused more catchment erosion and higher sediment flux through the Sudd marshes. The sedimentation rate in core 9509 increased during the AHP because of the greater importance of the WN sediment flux relative to the BN sediment flux. Saharan dust flux also decreased during the AHP reaching a minimum at ˜6 ka BP (core 9509) due to 'greening' of the Sahara desert. At the onset of S-1, the changes in Nile flow as determined by 87Sr/ 86Sr and climatic changes in the EM basin determined by δ 18O of planktonic foraminifera were simultaneous, confirming that such

  2. An Integrated Hydrological and Water Management Study of the Entire Nile River System - Lake Victoria to Nile Delta

    NASA Technical Reports Server (NTRS)

    Habib, Shahid; Zaitchik, Benjamin; Alo, Clement; Ozdogan, Mutlu; Anderson, Martha; Policelli, Fritz

    2011-01-01

    The Nile basin River system spans 3 million km(exp 2) distributed over ten nations. The eight upstream riparian nations, Ethiopia, Eretria, Uganda, Rwanda, Burundi, Congo, Tanzania and Kenya are the source of approximately 86% of the water inputs to the Nile, while the two downstream riparian countries Sudan and Egypt, presently rely on the river's flow for most of the their needs. Both climate and agriculture contribute to the complicated nature of Nile River management: precipitation in the headwaters regions of Ethiopia and Lake Victoria is variable on a seasonal and inter-annual basis, while demand for irrigation water in the arid downstream region is consistently high. The Nile is, perhaps, one of the most difficult trans-boundary water issue in the world, and this study would be the first initiative to combine NASA satellite observations with the hydrologic models study the overall water balance in a to comprehensive manner. The cornerstone application of NASA's Earth Science Research Results under this project are the NASA Land Data Assimilation System (LDAS) and the USDA Atmosphere-land Exchange Inverse (ALEXI) model. These two complementary research results are methodologically independent methods for using NASA observations to support water resource analysis in data poor regions. Where an LDAS uses multiple sources of satellite data to inform prognostic simulations of hydrological process, ALEXI diagnoses evapotranspiration and water stress on the basis of thermal infrared satellite imagery. Specifically, this work integrates NASA Land Data Assimilation systems into the water management decision support systems that member countries of the Nile Basin Initiative (NBI) and Regional Center for Mapping of Resources for Development (RCMRD, located in Nairobi, Kenya) use in water resource analysis, agricultural planning, and acute drought response to support sustainable development of Nile Basin water resources. The project is motivated by the recognition that

  3. Atypical cellular blue nevus or malignant blue nevus?*

    PubMed Central

    Daltro, Luise Ribeiro; Yaegashi, Lygia Bertalha; Freitas, Rodrigo Abdalah; Fantini, Bruno de Carvalho; Souza, Cacilda da Silva

    2017-01-01

    Blue nevus is a benign melanocytic lesion whose most frequent variants are dendritic (common) blue nevus and cellular blue nevus. Atypical cellular blue nevus presents an intermediate histopathology between the typical and a rare variant of malignant blue nevus/melanoma arising in a cellular blue nevus. An 8-year-old child presented a pigmented lesion in the buttock since birth, but with progressive growth in the last two years. After surgical excision, histopathological examination revealed atypical cellular blue nevus. Presence of mitoses, ulceration, infiltration, cytological atypia or necrosis may occur in atypical cellular blue nevus, making it difficult to differentiate it from melanoma. The growth of blue nevus is unusual and considered of high-risk for malignancy, being an indicator for complete resection and periodic follow-up of these patients. PMID:28225968

  4. ASSOCIATIONS BETWEEN TWO MOSQUITO POPULATIONS AND WEST NILE VIRUS IN HARRIS COUNTY, TEXAS, 2003–061

    PubMed Central

    DENNETT, JAMES A.; BALA, ADILELKHIDIR; WUITHIRANYAGOOL, TAWEESAK; RANDLE, YVONNE; SARGENT, CHRISTOPHER B.; GUZMAN, HILDA; SIIRIN, MARINA; HASSAN, HASSAN K.; REYNA-NAVA, MARTIN; UNNASCH, THOMAS R.; TESH, ROBERT B.; PARSONS, RAY E.; BUENO, RUDY

    2008-01-01

    Associations between Culex quinquefasciatus, Aedes albopictus and West Nile virus (WNV) activity, temperature, and rainfall in Harris County, Texas 2003–06 are discussed. Human cases were highly correlated to Cx. quinquefasciatus (r = 0.87) and Ae. albopictus (r = 0.78) pools, blue jays (r = 0.83), and Ae. albopictus collected (r = 0.71), but not Cx. quinquefasciatus collected (r = 0.45). Human cases were associated with temperature (r = 0.71), not rainfall (r = 0.29), whereas temperature correlated with Ae. albopictus and Cx. quinquefasciatus collections (r = 0.88 and 0.70, respectively) and Cx. quinquefasciatus pools (r = 0.75), but not Ae. albopictus pools (r = 0.55). Both species (collections and pools) and blue jays were weakly correlated (r ≤ 0.41) with rainfall, but blue jays were better correlated with Cx. quinquefasciatus pools (r = 0.87), compared with Ae. albopictus pools (r = 0.67), Ae. albopictus collections (r = 0.69), and Cx. quinquefasciatus collections (r = 0.46). Peak minimum infection rate for Cx. quinquefasciatus (4.55), and Ae. albopictus (4.41) was in August with highest human cases (17.87), blue jays (55.58), and temperature (29.01°C). Between both species, blood meal analysis indicated 68.18% of Cx. quinquefasciatus mammalian hosts were dog, while 22.72% were human, whereas Ae. albopictus had higher human (44.44%) but fewer dog hosts (22.22%). Ten bird species were identified as hosts for Cx. quinquefasciatus, with northern cardinal and blue jay representing 26.66% and 20.00%, respectively. No bird feeding activity was observed in Ae. albopictus. The earliest and latest human blood meal occurred in May (Ae. albopictus) and November (Cx. quinquefasciatus); 66.66% of human host identifications between both species occurred in October–November, after the seasonal human case peak. Based upon our data, WNV activity in both mosquito species warrants further investigation of their individual roles in WNV ecology within this region. PMID

  5. Associations between two mosquito populations and West Nile virus in Harris County, Texas, 2003-06.

    PubMed

    Dennett, James A; Bala, Adilelkhidir; Wuithiranyagool, Taweesak; Randle, Yvonne; Sargent, Christopher B; Guzman, Hilda; Siirin, Marina; Hassan, Hassan K; Reyna-Nava, Martin; Unnasch, Thomas R; Tesh, Robert B; Parsons, Ray E; Bueno, Rudy

    2007-09-01

    Associations between Culex quinquefasciatus, Aedes albopictus and West Nile virus (WNV) activity, temperature, and rainfall in Harris County, Texas 2003-06 are discussed. Human cases were highly correlated to Cx. quinquefasciatus (r = 0.87) and Ae. albopictus (r = 0.78) pools, blue jays (r = 0.83), and Ae. albopictus collected (r = 0.71), but not Cx. quinquefasciatus collected (r = 0.45). Human cases were associated with temperature (r = 0.71), not rainfall (r = 0.29), whereas temperature correlated with Ae. albopictus and Cx. quinquefasciatus collections (r = 0.88 and 0.70, respectively) and Cx. quinqueftsciatus pools (r = 0.75), but not Ae. albopictus pools (r = 0.55). Both species (collections and pools) and blue jays were weakly correlated (r 5 0.41) with rainfall, but blue jays were better correlated with Cx. quinquefasciatus pools (r = 0.87), compared with Ae. albopictus pools (r = 0.67), Ae. albopictus collections (r = 0.69), and Cx. quinquefasciatus collections (r = 0.46). Peak minimum infection rate for Cx. quinquefasciatus (4.55), and Ae. albopictus (4.41) was in August with highest human cases (17.87), blue jays (55.58), and temperature (29.01 degrees C). Between both species, blood meal analysis indicated 68.18% of Cx. quinquefasciatus mammalian hosts were dog, while 22.72% were human, whereas Ae. albopictus had higher human (44.44%) but fewer dog hosts (22.22%). Ten bird species were identified as hosts for Cx. quinquefasciatus, with northern cardinal and blue jay representing 26.66% and 20.00%, respectively. No bird feeding activity was observed in Ae. albopictus. The earliest and latest human blood meal occurred in May (Ae. albopictus) and November (Cx. quinquefasciatus); 66.66% of human host identifications between both species occurred in October-November, after the seasonal human case peak. Based upon our data, WNV activity in both mosquito species warrants further investigation of their individual roles in WNV ecology within this region.

  6. Neuromuscular Manifestations of West Nile Virus Infection

    PubMed Central

    Leis, A. Arturo; Stokic, Dobrivoje S.

    2012-01-01

    The most common neuromuscular manifestation of West Nile virus (WNV) infection is a poliomyelitis syndrome with asymmetric paralysis variably involving one (monoparesis) to four limbs (quadriparesis), with or without brainstem involvement and respiratory failure. This syndrome of acute flaccid paralysis may occur without overt fever or meningoencephalitis. Although involvement of anterior horn cells in the spinal cord and motor neurons in the brainstem are the major sites of pathology responsible for neuromuscular signs, inflammation also may involve skeletal or cardiac muscle (myositis, myocarditis), motor axons (polyradiculitis), and peripheral nerves [Guillain–Barré syndrome (GBS), brachial plexopathy]. In addition, involvement of spinal sympathetic neurons and ganglia provides an explanation for autonomic instability seen in some patients. Many patients also experience prolonged subjective generalized weakness and disabling fatigue. Despite recent evidence that WNV may persist long-term in the central nervous system or periphery in animals, the evidence in humans is controversial. WNV persistence would be of great concern in immunosuppressed patients or in those with prolonged or recurrent symptoms. Support for the contention that WNV can lead to autoimmune disease arises from reports of patients presenting with various neuromuscular diseases that presumably involve autoimmune mechanisms (GBS, other demyelinating neuropathies, myasthenia gravis, brachial plexopathies, stiff-person syndrome, and delayed or recurrent symptoms). Although there is no specific treatment or vaccine currently approved in humans, and the standard remains supportive care, drugs that can alter the cascade of immunobiochemical events leading to neuronal death may be potentially useful (high-dose corticosteroids, interferon preparations, and intravenous immune globulin containing WNV-specific antibodies). Human experience with these agents seems promising based on anecdotal reports

  7. West Nile Virus–associated Flaccid Paralysis Outcome

    PubMed Central

    Bode, Amy V.; Marfin, Anthony A.; Campbell, Grant L.; Pape, John; Biggerstaff, Brad J.; Petersen, Lyle R.

    2006-01-01

    We report 1-year follow-up data from a longitudinal prospective cohort study of patients with West Nile virus–associated paralysis. As in the 4-month follow-up, a variety of recovery patterns were observed, but persistent weakness was frequent. Respiratory involvement was associated with considerable illness and death. PMID:16704798

  8. West Nile virus antibody prevalence in wild mammals, southern Wisconsin

    USGS Publications Warehouse

    Docherty, D.E.; Samuel, M.D.; Nolden, C.A.; Egstad, Kristina F.; Griffin, K.M.

    2006-01-01

    Twenty percent prevalence of West Nile virus antibody was found in free-ranging medium-sized Wisconsin mammals. No significant differences were noted in antibody prevalence with regard to sex, age, month of collection, or species. Our results suggest a similar route of infection in these mammals.

  9. West Nile Virus Surveillance, Guadeloupe, 2003–2004

    PubMed Central

    Blitvich, Bradley J.; Pradel, Jennifer; Molia, Sophie; Vachiéry, Nathalie; Pallavicini, Guillaume; Marlenee, Nicole L.; Zientara, Stéphan; Petitclerc, Martial; Martinez, Dominique

    2005-01-01

    We conducted extensive surveillance for West Nile virus infection in equines and chickens in Guadeloupe in 2003–2004. We showed a high seroprevalence in equines in 2003 related to biome, followed by a major decrease in virus circulation in 2004. No human or equine cases were reported during the study. PMID:16022789

  10. STS-56 Earth observation of the northeastern Nile Delta

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-56 Earth observation of the northeastern Nile Delta was photographed from the Earth-orbiting Discovery, Orbiter Vehicle (OV) 103. The branch of the Nile featured in the frame is Daimietta. The Suez Canal marks the boundary of the Nile Delta agriculture and the Sinai Desert to the right. Lake Masada, the dark waterlogged area to the west (left) of Port Said is becoming more saline as the Aswan Dam has reduced sediment downstream. This sediment reduction, according to NASA scientists studying the STS-56 photography, has resulted in increased coastal erosion and the intrusion of a salt-water lens to the ground water, particularly in the northeastern portions of the delta. Center pivot irrigation fields are located along either side of the Ramses Canal, which connects the Daimietta Nile with Great Bitter Lake. This canal has been re-dug three or four times in the past 3,000 years. Historians note that the canal's most famous use was as the departure point of the fleet of Pharaoh Necho.

  11. Increase in West Nile neuroinvasive disease after Hurricane Katrina.

    PubMed

    Caillouët, Kevin A; Michaels, Sarah R; Xiong, Xu; Foppa, Ivo; Wesson, Dawn M

    2008-05-01

    After Hurricane Katrina, the number of reported cases of West Nile neuroinvasive disease (WNND) sharply increased in the hurricane-affected regions of Louisiana and Mississippi. In 2006, a >2-fold increase in WNND incidence was observed in the hurricane-affected areas than in previous years.

  12. Increase in West Nile Neuroinvasive Disease after Hurricane Katrina

    PubMed Central

    Michaels, Sarah R.; Xiong, Xu; Foppa, Ivo; Wesson, Dawn M.

    2008-01-01

    After Hurricane Katrina, the number of reported cases of West Nile neuroinvasive disease (WNND) sharply increased in the hurricane-affected regions of Louisiana and Mississippi. In 2006, a >2-fold increase in WNND incidence was observed in the hurricane-affected areas than in previous years. PMID:18439367

  13. Magpies as Hosts for West Nile Virus, Southern France

    PubMed Central

    Gauthier-Clerc, Michel; Sabatier, Philippe; Grège, Océane; Greenland, Timothy; Leblond, Agnès; Lafaye, Murielle; Zeller, Hervé G.

    2008-01-01

    European magpies (Pica pica) from southern France were tested for antibodies to West Nile virus (WNV) and viral shedding in feces during spring–autumn 2005. Results suggest that this peridomestic species may be a suitable sentinel species and a relevant target for additional investigations on WNV ecology in Europe. PMID:18258098

  14. Magpies as hosts for West Nile virus, southern France.

    PubMed

    Jourdain, Elsa; Gauthier-Clerc, Michel; Sabatier, Philippe; Grège, Océane; Greenland, Timothy; Leblond, Agnès; Lafaye, Murielle; Zeller, Hervé G

    2008-01-01

    European magpies (Pica pica) from southern France were tested for antibodies to West Nile virus (WNV) and viral shedding in feces during spring-autumn 2005. Results suggest that this peridomestic species may be a suitable sentinel species and a relevant target for additional investigations on WNV ecology in Europe.

  15. Domestic goose model for West Nile virus vaccine efficiency testing

    USDA-ARS?s Scientific Manuscript database

    West Nile virus (WNV) is an emergent pathogen in the Americas, first reported in New York during 1999, and has since spread across the United States (USA), Central and South America causing neurological disease in humans, horses and some bird species, including domestic geese. No WNV vaccines are li...

  16. Corvidae feather pulp and West Nile virus detection

    USGS Publications Warehouse

    Docherty, D.E.; Romaine Long, R.; Griffin, Katie M.; Saito, E.K.

    2004-01-01

    We evaluated cloacal swab, vascular pulp of flight feather, and kidney and spleen pool samples from carcasses of members of the family Corvidae as sources of West Nile virus (WNV). The cloacal swab, kidney and spleen pool, and feather pulp were the source of WNV in 38%, 43%, and 77%, respectively, of the carcasses.

  17. Outbreak of West Nile Virus Infection in Greece, 2010

    PubMed Central

    Papa, Anna; Theocharopoulos, George; Dougas, Georgios; Athanasiou, Maria; Detsis, Marios; Baka, Agoritsa; Lytras, Theodoros; Mellou, Kassiani; Bonovas, Stefanos; Panagiotopoulos, Takis

    2011-01-01

    During 2010, an outbreak of West Nile virus infection occurred in Greece. A total of 197 patients with neuroinvasive disease were reported, of whom 33 (17%) died. Advanced age and a history of heart disease were independently associated with death, emphasizing the need for prevention of this infection in persons with these risk factors. PMID:22000357

  18. Environmental Predictors of Human West Nile Virus Infections, Colorado

    PubMed Central

    Juliusson, Lara; Vogt, Richard L.

    2007-01-01

    To determine whether environmental surveillance of West Nile virus–positive dead birds, mosquito pools, equines, and sentinel chickens helped predict human cases in metropolitan Denver, Colorado, during 2003, we analyzed human surveillance data and environmental data. Birds successfully predicted the highest proportion of human cases, followed by mosquito pools, and equines. PMID:18217573

  19. Is Solar Variability Reflected in the Nile River?

    NASA Technical Reports Server (NTRS)

    Ruzmaikin, Alexander; Feynman, Joan; Yung, Yuk L.

    2006-01-01

    We investigate the possibility that solar variability influences North African climate by using annual records of the water level of the Nile collected in 622-1470 A.D. The time series of these records are nonstationary, in that the amplitudes and frequencies of the quasi-periodic variations are time-dependent. We apply the Empirical Mode Decomposition technique especially designed to deal with such time series. We identify two characteristic timescales in the records that may be linked to solar variability: a period of about 88 years and one exceeding 200 years. We show that these timescales are present in the number of auroras reported per decade in the Northern Hemisphere at the same time. The 11-year cycle is seen in the Nile's high-water level variations, but it is damped in the low-water anomalies. We suggest a possible physical link between solar variability and the low-frequency variations of the Nile water level. This link involves the influence of solar variability on the atmospheric Northern Annual Mode and on its North Atlantic Ocean and Indian Ocean patterns that affect the rainfall over the sources of the Nile in eastern equatorial Africa.

  20. West Nile Virus: Biology, Transmission, and Human Infection

    PubMed Central

    Colpitts, Tonya M.; Conway, Michael J.; Montgomery, Ruth R.

    2012-01-01

    Summary: West Nile Virus was introduced into the Western Hemisphere during the late summer of 1999 and has been causing significant and sometimes severe human diseases since that time. This article briefly touches upon the biology of the virus and provides a comprehensive review regarding recent discoveries about virus transmission, virus acquisition, and human infection and disease. PMID:23034323

  1. West Nile Virus Isolation from Equines in Argentina, 2006

    PubMed Central

    Barrandeguy, María; Fabbri, Cintia; Garcia, Jorge B.; Vissani, Aldana; Trono, Karina; Gutierrez, Gerónimo; Pigretti, Santiago; Menchaca, Hernán; Garrido, Nelson; Taylor, Nora; Fernandez, Fernando; Levis, Silvana; Enría, Delia

    2006-01-01

    West Nile virus (WNV) was isolated from the brains of 3 horses that died from encephalitis in February 2006. The horses were from different farms in central Argentina and had not traveled outside the country. This is the first isolation of WNV in South America. PMID:17176571

  2. West Nile virus infection in killer whale, Texas, USA, 2007.

    PubMed

    St Leger, Judy; Wu, Guang; Anderson, Mark; Dalton, Les; Nilson, Erika; Wang, David

    2011-08-01

    In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WNV should be considered in cases of encephalitis in cetaceans.

  3. West Nile Virus Infection in Killer Whale, Texas, USA, 2007

    PubMed Central

    Wu, Guang; Anderson, Mark; Dalton, Les; Nilson, Erika; Wang, David

    2011-01-01

    In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WNV should be considered in cases of encephalitis in cetaceans. PMID:21801643

  4. Agricultural Model for the Nile Basin Decision Support System

    NASA Astrophysics Data System (ADS)

    van der Bolt, Frank; Seid, Abdulkarim

    2014-05-01

    To analyze options for increasing food supply in the Nile basin the Nile Agricultural Model (AM) was developed. The AM includes state-of-the-art descriptions of biophysical, hydrological and economic processes and realizes a coherent and consistent integration of hydrology, agronomy and economics. The AM covers both the agro-ecological domain (water, crop productivity) and the economic domain (food supply, demand, and trade) and allows to evaluate the macro-economic and hydrological impacts of scenarios for agricultural development. Starting with the hydrological information from the NileBasin-DSS the AM calculates the available water for agriculture, the crop production and irrigation requirements with the FAO-model AquaCrop. With the global commodity trade model MAGNET scenarios for land development and conversion are evaluated. The AM predicts consequences for trade, food security and development based on soil and water availability, crop allocation, food demand and food policy. The model will be used as a decision support tool to contribute to more productive and sustainable agriculture in individual Nile countries and the whole region.

  5. STS-56 Earth observation of the northeastern Nile Delta

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-56 Earth observation of the northeastern Nile Delta was photographed from the Earth-orbiting Discovery, Orbiter Vehicle (OV) 103. The branch of the Nile featured in the frame is Daimietta. The Suez Canal marks the boundary of the Nile Delta agriculture and the Sinai Desert to the right. Lake Masada, the dark waterlogged area to the west (left) of Port Said is becoming more saline as the Aswan Dam has reduced sediment downstream. This sediment reduction, according to NASA scientists studying the STS-56 photography, has resulted in increased coastal erosion and the intrusion of a salt-water lens to the ground water, particularly in the northeastern portions of the delta. Center pivot irrigation fields are located along either side of the Ramses Canal, which connects the Daimietta Nile with Great Bitter Lake. This canal has been re-dug three or four times in the past 3,000 years. Historians note that the canal's most famous use was as the departure point of the fleet of Pharaoh Necho.

  6. Human Streptococcus agalactiae isolate in Nile tilapia (Oreochromis niloticus).

    PubMed

    Evans, Joyce J; Klesius, Phillip H; Pasnik, David J; Bohnsack, John F

    2009-05-01

    Streptococcus agalactiae, the Lancefield group B streptococcus (GBS) long recognized as a mammalian pathogen, is an emerging concern with regard to fish. We show that a GBS serotype Ia multilocus sequence type ST-7 isolate from a clinical case of human neonatal meningitis caused disease and death in Nile tilapia (Oreochromis niloticus).

  7. Substratum choice for nesting in male Nile tilapia Oreochromis niloticus.

    PubMed

    Mendonça, F Z; Volpato, G L; Costa-Ferreira, R S; Gonçalves-de-Freitas, E

    2010-10-01

    Four substrata were offered to groups of adult Nile tilapia Oreochromis niloticus (one male and two females) simultaneously: pure sand, a mixture of sand and shells, stones and no substratum. The results showed that males chose to dig nests in a lighter and more homogeneous substratum.

  8. West Nile Virus Antibodies in Wild Birds, Morocco, 2008

    PubMed Central

    Baouab, Riad E.; Soriguer, Ramon; Fassi-Fihri, Ouafaa; Llorente, Francisco; Jímenez-Clavero, Miguel Angel

    2009-01-01

    To determine circulation of West Nile virus (WNV) during nonepidemic times, we serosurveyed wild birds of Morocco in 2008. We found antibodies against WNV in 12 (3.5%) birds, against Usutu virus in 1 (0.3%), and against both in 2 (0.6%). High WNV prevalence among juvenile birds suggests local virus circulation among resident birds. PMID:19861065

  9. Purpura fulminans associated with acute West Nile virus encephalitis.

    PubMed

    Shah, Sheevam; Fite, Laura Paul; Lane, Natalie; Parekh, Palak

    2016-02-01

    Purpura fulminans is a progressive thrombotic disorder that presents with widespread purpura due to deficiency or dysfunction of protein C or protein S. Lesions present as well-demarcated erythematous macules that progress to irregular areas of hemorrhagic necrosis.West Nile virus is a member of the Flaviviridae family transmitted to humans through the bite of various mosquito species. It manifests as West Nile fever in 25% of those infected and less commonly as neuroinvasive disease. An African American man in his fortiespresented with altered mental status and was noted to have evidence of disseminated intravascular coagulation according to his lab data. He then developed dusky skin discoloration and systemic flaccid bullae with desquamation. Biopsy was consistent with purpura fulminans and the patient eventually developed symmetric peripheral gangrene, requiring amputations of all four extremities. Infectious work up revealed positive testing for IgM and IgG antibodies in serum and cerebrospinal fluid leading to the diagnosis of acute West Nile Virus encephalitis. We present this case to describe the rarely reported association of purpura fulminans with West Nile Virus infection. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. West Nile Virus Seroprevalence, Connecticut, USA, 2000-2014.

    PubMed

    Cahill, Megan E; Yao, Yi; Nock, David; Armstrong, Philip M; Andreadis, Theodore G; Diuk-Wasser, Maria A; Montgomery, Ruth R

    2017-04-01

    West Nile virus (WNV) infection is mainly asymptomatic but can be severe in elderly persons. As part of studies on immunity and aging in Connecticut, USA, we detected WNV seroconversion in 8.5% of nonimmunosuppressed and 16.8% of immunosuppressed persons. Age was not a significant seroconversion factor. Our findings suggest that immune factors affect seroconversion.

  11. West Nile Virus Transmission in Resident Birds, Dominican Republic

    PubMed Central

    Robbins, Mark B.; Klenk, Kaci; Blitvich, Bradley J.; Marlenee, Nicole L.; Burkhalter, Kristen L.; Gubler, Duane J.; Gonzálvez, Guillermo; Peña, Carlos J.; Peterson, A. Townsend; Komar, Nicholas

    2003-01-01

    We report West Nile virus (WNV) activity in the Dominican Republic for the first time. Specific anti-WNV antibodies were detected in 5 (15%) of 33 resident birds sampled at one location in November 2002. One seropositive bird was <4 months old, indicating a recent infection. PMID:14609467

  12. Is Solar Variability Reflected in the Nile River?

    NASA Technical Reports Server (NTRS)

    Ruzmaikin, Alexander; Feynman, Joan; Yung, Yuk L.

    2006-01-01

    We investigate the possibility that solar variability influences North African climate by using annual records of the water level of the Nile collected in 622-1470 A.D. The time series of these records are nonstationary, in that the amplitudes and frequencies of the quasi-periodic variations are time-dependent. We apply the Empirical Mode Decomposition technique especially designed to deal with such time series. We identify two characteristic timescales in the records that may be linked to solar variability: a period of about 88 years and one exceeding 200 years. We show that these timescales are present in the number of auroras reported per decade in the Northern Hemisphere at the same time. The 11-year cycle is seen in the Nile's high-water level variations, but it is damped in the low-water anomalies. We suggest a possible physical link between solar variability and the low-frequency variations of the Nile water level. This link involves the influence of solar variability on the atmospheric Northern Annual Mode and on its North Atlantic Ocean and Indian Ocean patterns that affect the rainfall over the sources of the Nile in eastern equatorial Africa.

  13. Geochronology of wadi tushka: lost tributary of the nile.

    PubMed

    Haynes, C V

    1980-10-03

    The Sadat Canal, now under construction, is designed to drain excess water from Lake Nasser to the Western Desert by way of Wadi Tushka, a sand-filled, dry-wash tributary of the Nile 34 kilometers north of Abu Simbel. Core-drilling logs made by the Aswan High Dam Authority prior to excavation of the Sadat Canal and along 48 kilometers of its axis reveal as much as 33 meters of unconsolidated sand and gravel over Mesozoic bedrock and under surficial dune sand and playa muds of Holocene age. Excavation of the canal revealed Acheulean artifacts 6.7 meters below the surface in fluvial sediments capped by a buried, red calcic paleosol. These data are interpreted as evidence for the existence of a major tributary of the Nile during the late middle Pleistocene. The tributary drained the Kiseiba-Dungul Depression and possibly the Kharga Depression as well. Chalcedony-armored mudstones in the depressions are believed to be saline lake deposits possibly related to a lake that drained to the Nile by way of Wadi Tushka, thus entrenching the divide between the depression and the valley. Gross correlations with Pleistocene deposits of the Nile Valley and the Kharga Depression are based upon archeological evidence only until more precise geochronology can be applied to the problem.

  14. West Nile Virus Seroprevalence, Connecticut, USA, 2000–2014

    PubMed Central

    Cahill, Megan E.; Yao, Yi; Nock, David; Armstrong, Philip M.; Andreadis, Theodore G.; Diuk-Wasser, Maria A.

    2017-01-01

    West Nile virus (WNV) infection is mainly asymptomatic but can be severe in elderly persons. As part of studies on immunity and aging in Connecticut, USA, we detected WNV seroconversion in 8.5% of nonimmunosuppressed and 16.8% of immunosuppressed persons. Age was not a significant seroconversion factor. Our findings suggest that immune factors affect seroconversion. PMID:28322715

  15. Holocene evolution of the River Nile drainage system as revealed from the Lake Dendi sediment record, central Ethiopian highlands

    NASA Astrophysics Data System (ADS)

    Wagner, B.; Viehberg, F. A.; Wennrich, V.; Junginger, A.; Kolvenbach, A.; Rethemeyer, J.; Schaebitz, F.; Schmiedl, G. H.

    2015-12-01

    A 12 m long sediment sequence from Dendi Crater lakes, located on the central Ethiopian Plateau, was analysed with sedimentological and geochemical methods to reconstruct the regional environmental history. Bulk organic carbon samples from 23 horizons throughout the sequence were used for AMS radiocarbon dating and indicate that the sediment sequence spans the last ca. 12 cal kyr BP. Microscope analyses and sedimentological data reveal three tephra layers, of which the most prominent layer with a thickness of ~2 m was deposited at 10.2 cal kyr BP and probably originates from an eruption of the Wenchi crater 12 km to the west of the Dendi lakes. Sedimentological data of the pelagic deposits indicate shifts in erosion and rainfall throughout the record. A decrease in Ca and Sr at 11.6 cal kyr BP is related to the shift of less humid condition during the Younger Dryas (YD) to the return to full humid conditions of the African Humid Period (AHP). Single thin horizons with high carbonate content or high Ti and K imply that short spells of dry conditions and significantly increased rainfall superimpose the generally more humid conditions during the AHP. The end of the AHP is gradual. Relatively stable and less humid conditions characterised the Dendi Crater lakes until around 3.9 cal kyr BP. A highly variable increase in clastic matter over the last 1500 years indicates higher erosion due to short-term variations in precipitation within the Dendi catchment. Overall, the sediment record suggests moderate change of precipitation during the Holocene, which is probably due to their exposed location in the Ethiopian highlands. The data from the Dendi Crater lakes show, in concert with other records from the Nile catchment and the Eastern Mediterranean Sea (EMS), that the Blue Nile provided the main freshwater source for maintaining EMS stratification and sapropel S1 formation between ca. 10.0 and 8.7 cal kyr BP. Subsequent aridification is recorded from equatorial East Africa

  16. [Blue light and eye health].

    PubMed

    Zou, Leilei; Dai, Jinhui

    2015-01-01

    Blue light, with the wavelength between 400 nm and 500 nm, has caused public concern because of the injury to the retinal cells. Meanwhile, it is important in circadian rhythm regulation, scotopic vision and ocular growth. Is the blue light safe? Should it be eliminated from the daily life? Here we review the effect and safety of the blue light.

  17. Learning the Blues. [Lesson Plan].

    ERIC Educational Resources Information Center

    2001

    This lesson introduces students to the "blues," one of the most distinctive and influential elements of African-American musical tradition. With this lesson plan, students can take a virtual field trip to Memphis, Tennessee, one of the prominent centers of blues activities, and explore the history of the blues in the work of W. C. Handy…

  18. VecTest as Diagnostic and Surveillance Tool for West Nile Virus in Dead Birds

    PubMed Central

    Okoniewski, Joseph C.; Therrien, Joseph E.; Kramer, Laura D.; Kauffman, Elizabeth B.; Eidson, Millicent

    2004-01-01

    The VecTest antigen-capture assay for West Nile virus was performed on oral and tissue swabs from dead birds in New York State from April 2003 through July 2004. Results were compared with those from real-time reverse transcriptase–polymerase chain reaction of kidney or brain. Oral VecTest sensitivity is adequate for surveillance in American Crows (Corvus brachyrhynchos) (87%), Blue Jays (Cyanocitta cristata) (80%), and House Sparrows (Passer domesticus) (76%). Oral VecTest performed well for small samples of American Kestrels (Falco sparverius), Northern Cardinals (Cardinalis cardinalis), Common Grackles (Quiscalus quiscula), and House Finches (Carpodacus mexicanus). Poor sensitivity occurred in most raptors, Mourning Doves (Zenaida macroura), Fish Crows (Corvus ossifragus), and American Robins (Turdus migratorius). Specificity was excellent (98%), except for false-positive results that occurred mostly in Gray Catbirds (Dumatella carolinensis), Green Herons (Butorides virescens), and tests of blood and tissues. Feather pulp and kidney may be useful for VecTest assays in corvids. PMID:15663856

  19. Mechanisms of the Impacts of Climate Change on the Hydrology of the Eastern Nile Basin

    NASA Astrophysics Data System (ADS)

    Siam, M.; Eltahir, E. A.

    2013-12-01

    The general circulation models (GCMs), are the primary tools for climate change studies. Here, we investigate the impacts of climate change on the hydrological cycle of the Upper Blue Nile (UBN) using carefully selected GCMs. We develop a new criterion to select suitable GCMs for climate change studies based on the runoff elasticity (percent change in runoff per percent change in rainfall). We analyze 18 high and medium resolutions CMIP3 and CMIP5 GCMs. Only (HadGEM and ECHAM) GCMs from CMIP3 and (CSIRO and HadGEM-CC) from CMIP5 reasonably simulate the hydrological cycle of the UBN and its runoff elasticity. These two models simulate small changes in rainfall over the UBN for the period (2010-2040) and (2040-2070) compared to the control period (1970-2000). Further investigation reveals that the changes in rainfall over the UBN are shaped by two competing mechanisms: (i) changes in the specific humidity over the Indian Ocean and surrounding regions, and (ii) changes in Indian monsoon circulation during July and August. The specific humidity over the Indian Ocean increases in the future. On the other hand, the change in the Indian monsoon circulation remotely impacts the convergence of air in the boundary layer over the UBN. The net effect of these two mechanisms determines the sign and magnitude of climate change impacts on the convergence of moisture and rainfall over the UBN.

  20. Isolation of two strains of West Nile virus during an outbreak in southern Russia, 1999.

    PubMed Central

    Lvov, D. K.; Butenko, A. M.; Gromashevsky, V. L.; Larichev, V. P.; Gaidamovich, S. Y.; Vyshemirsky, O. I.; Zhukov, A. N.; Lazorenko, V. V.; Salko, V. N.; Kovtunov, A. I.; Galimzyanov, K. M.; Platonov, A. E.; Morozova, T. N.; Khutoretskaya, N. V.; Shishkina, E. O.; Skvortsova, T. M.

    2000-01-01

    From July to September 1999, a widespread outbreak of meningoencephalitis associated with West Nile virus (Flavivirus, Flaviviridae) occurred in southern Russia, with hundreds of cases and dozens of deaths. Two strains of West Nile virus isolated from patient serum and brain-tissue samples reacted in hemagglutination-inhibition and neutralization tests with patients' convalescent-phase sera and immune ascites fluid from other strains of West Nile virus. PMID:10905970

  1. The Blue Emu

    NASA Technical Reports Server (NTRS)

    Descalzi, Doug; Gillett, John; Gordon, Carlton; Keener, ED; Novak, Ken; Puente, Laura

    1993-01-01

    The primary goal in designing the Blue Emu was to provide an airline with a cost efficient and profitable means of transporting passengers between the major cities in Aeroworld. The design attacks the market where a demand for inexpensive transportation exists and for this reason the Blue Emu is an attractive investment for any airline. In order to provide a profitable aircraft, special attention was paid to cost and economics. For example, in manufacturing, simplicity was stressed in structural design to reduce construction time and cost. Aerodynamic design employed a tapered wing which reduced the induced drag coefficient while also reducing the weight of the wing. Even the propulsion system was selected with cost effectiveness in mind, yet also to maintain the marketability of the aircraft. Thus, in every aspect of the design, consideration was given to economics and marketability of the final product.

  2. Pluto Blue Sky

    NASA Image and Video Library

    2015-10-08

    Pluto's haze layer shows its blue color in this picture taken by the New Horizons Ralph/Multispectral Visible Imaging Camera (MVIC). The high-altitude haze is thought to be similar in nature to that seen at Saturn's moon Titan. The source of both hazes likely involves sunlight-initiated chemical reactions of nitrogen and methane, leading to relatively small, soot-like particles (called tholins) that grow as they settle toward the surface. This image was generated by software that combines information from blue, red and near-infrared images to replicate the color a human eye would perceive as closely as possible. http://photojournal.jpl.nasa.gov/catalog/PIA19964

  3. First molecular analysis of West Nile virus during the 2013 outbreak in Croatia.

    PubMed

    Kurolt, Ivan C; Krajinović, Vladimir; Topić, Antea; Kuzman, Ilija; Baršić, Bruno; Markotić, Alemka

    2014-08-30

    This is the second subsequent year of West Nile neuroinvasive disease (WNND) outbreak in Croatia. Between July and October 2013, 22 patients presented with symptoms of WNND: all with meningitis and 18 additionally with encephalitis. In contrast to 2012, where six autochthonous infections were confirmed in eastern Croatia, the majority of this year's cases occurred in and around the city of Zagreb, where no West Nile virus infections have been observed before. Viral RNA was recovered from two patients and phylogenetic analyses revealed West Nile virus lineage 2. This represents the first molecular characterization and phylogenetic analysis of the circulating West Nile virus strain in Croatia.

  4. Voyager 1 'Blue Movie'

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This is the original Voyager 'Blue Movie' (so named because it was built from Blue filter images). It records the approach of Voyager 1 during a period of over 60 Jupiter days. Notice the difference in speed and direction of the various zones of the atmosphere. The interaction of the atmospheric clouds and storms shows how dynamic the Jovian atmosphere is.

    As Voyager 1 approached Jupiter in 1979, it took images of the planet at regular intervals. This sequence is made from 66 images taken once every Jupiter rotation period (about 10 hours). This time-lapse movie uses images taken every time Jupiter longitude 68W passed under the spacecraft. These images were acquired in the Blue filter from Jan. 6 to Feb. 3 1979. The spacecraft flew from 58 million kilometers to 31 million kilometers from Jupiter during that time.

    This time-lapse movie was produced at JPL by the Image Processing Laboratory in 1979.

  5. Blue metal-poor stars

    NASA Astrophysics Data System (ADS)

    Preston, George W.; Sneden, Christopher

    2004-12-01

    We review the discovery of blue metal-poor (BMP) stars and the resolution of this population into blue stragglers and intermediate-age Main-Sequence stars by use of binary fractions. We show that the specific frequencies of blue stragglers in the halo field and in globular clusters differ by an order of magnitude. We attribute this difference to the different modes of production of these two populations. We report carbon and s-process enrichment among very metal-poor field blue stragglers and discuss how this result can be used to further resolve field blue stragglers into groups formed during RGB and AGB evolution of their erstwhile primary companions.

  6. West Nile virus Epidemic in Horses, Tuscany Region, Italy

    PubMed Central

    Autorino, Gian Luca; Battisti, Antonio; Deubel, Vincent; Ferrari, Giancarlo; Forletta, Riccardo; Giovannini, Armando; Lelli, Rossella; Murri, Severine; Scicluna, Maria Teresa

    2002-01-01

    During the late summer of 1998, veterinary authorities in Tuscany, Italy, received reports of cases of neurologic disease among horses residing in a large wetland area located in the provinces of Florence and Pistoia. West Nile virus was isolated from two of the six horses that died or were euthanized. A retrospective epidemiologic study identified 14 clinical neurologic cases that occurred from August 20 to October 6 (attack rate of 2.8%). A serologic survey conducted over a 700-km2 area in stables with and without apparent clinical cases confirmed a wider spread of the infection, with an overall seroprevalence rate of 38% in the affected area. No significant differences in age-specific prevalence were observed, suggesting that the horses residing in the area had not been exposed previously to West Nile virus and supporting the hypothesis of its introduction in the wetland area during the first half of 1998. PMID:12498650

  7. Alexander the Great and West Nile Virus Encephalitis

    PubMed Central

    Marr, John S.

    2003-01-01

    Alexander the Great died in Babylon in 323 BC. His death at age 32 followed a 2-week febrile illness. Speculated causes of death have included poisoning, assassination, and a number of infectious diseases. One incident, mentioned by Plutarch but not considered by previous investigators, may shed light on the cause of Alexander’s death. The incident, which occurred as he entered Babylon, involved a flock of ravens exhibiting unusual behavior and subsequently dying at his feet. The inexplicable behavior of ravens is reminiscent of avian illness and death weeks before the first human cases of West Nile virus infection were identified in the United States. We posit that Alexander may have died of West Nile encephalitis. PMID:14725285

  8. Recent progress in West Nile virus diagnosis and vaccination

    PubMed Central

    2012-01-01

    West Nile virus (WNV) is a positive-stranded RNA virus belonging to the Flaviviridae family, a large family with 3 main genera (flavivirus, hepacivirus and pestivirus). Among these viruses, there are several globally relevant human pathogens including the mosquito-borne dengue virus (DENV), yellow fever virus (YFV), Japanese encephalitis virus (JEV) and West Nile virus (WNV), as well as tick-borne viruses such as tick-borne encephalitis virus (TBEV). Since the mid-1990s, outbreaks of WN fever and encephalitis have occurred throughout the world and WNV is now endemic in Africa, Asia, Australia, the Middle East, Europe and the Unites States. This review describes the molecular virology, epidemiology, pathogenesis, and highlights recent progress regarding diagnosis and vaccination against WNV infections. PMID:22380523

  9. Monitoring the urbanization of the Nile Delta, Egypt.

    SciTech Connect

    Sultan, M.; Fiske, M.; Stein, T.; Gamal, M.; El Araby, H.; Madani, A.; Mehanee, S.; Becker, R.; Environmental Research; Washington Univ.; Cairo Univ. Center for Environmental Hazard Mitigation

    1999-11-01

    Comparisons of satellite images of the Nile Delta, acquired in 1972, 1984 and 1990, indicate that urban growth is endangering Egypt's agricultural productivity. Urban areas occupied a minimum of 3.6%, 4.7% and 5.7% of the Delta in 1972, 1984 and 1990, respectively, an increase of 58% in 18 years. Approximately half of this increase occurred between 1984 and 1990. If this trend continues, Egypt could lose 12% of its total agricultural area to urbanization by 2010. Despite the fact that growth is pronounced around the cities, it is the growth around the thousands of small villages that poses the largest threat to the agricultural productivity of the Nile Delta. The cumulative growth rate for the cities and large villages between 1972 and 1990 is 37%, and that for the small villages is 77% for the same time period.

  10. Alexander the Great and West Nile virus encephalitis.

    PubMed

    Marr, John S; Calisher, Charles H

    2003-12-01

    Alexander the Great died in Babylon in 323 BC. His death at age 32 followed a 2-week febrile illness. Speculated causes of death have included poisoning; assassination, and a number of infectious diseases. One incident, mentioned by Plutarch but not considered by previous investigators, may shed light on the cause of Alexander's death. The incident, which occurred as he entered Babylon, involved a flock of ravens exhibiting unusual behavior and subsequently dying at his feet. The inexplicable behavior of ravens is reminiscent of avian illness and death weeks before the first human cases of West Nile virus infection were identified in the United States. We posit that Alexander may have died of West Nile virus encephalitis.

  11. Nile River, Lake Nasser, Aswan High Dam, Egypt, Africa

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Lake Nasser, (24.0N, 33.0E) at the Aswan High Dam on the Nile River, in Egypt is the world's second largest artificial lake, extending 500 km, in length and about 5000 sq. km. in area. The lake has a storage capacity sufficient to irrigate farms in Egypt and Sudan year round allowing up to three harvests per year. Other benefits include year round river navagation, hydroelectric power, more fish harvests, reduced flooding and more industrial employment. opportunites.

  12. Nile River, Lake Nasser, Aswan High Dam, Egypt, Africa

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Lake Nasser, (24.0N, 33.0E) at the Aswan High Dam on the Nile River, in Egypt is the world's second largest artificial lake, extending 500 km, in length and about 5000 sq. km. in area. The lake has a storage capacity sufficient to irrigate farms in Egypt and Sudan year round allowing up to three harvests per year. Other benefits include year round river navagation, hydroelectric power, more fish harvests, reduced flooding and more industrial employment. opportunites.

  13. West Nile virus infections in humans--focus on Greece.

    PubMed

    Papa, Anna

    2013-10-01

    West Nile virus is a mosquito-borne flavivirus causing to humans a variety of symptoms, from asymptomatic or mild infection, to severe, and often fatal, infection of the central nervous system. The present review aims to describe the main clinical characteristics of the disease, to provide the recent epidemiological data, including those from the recent outbreaks in Greece, and to discuss the environmental factors which might play a role in the virus emergence and its wider dispersal.

  14. The Holocene Geoarchaeology of the Desert Nile in Northern Sudan

    NASA Astrophysics Data System (ADS)

    Woodward, Jamie; Macklin, Mark; Spencer, Neal; Welsby, Derek; Dalton, Matthew; Hay, Sophie; Hardy, Andrew

    2016-04-01

    Invited Paper Forty years ago Colin Renfrew declared that "every archaeological problem starts as a problem in geoarchaeology" (Renfrew, 1976 p. 2). With this assertion in mind, this paper draws upon the findings from field research in two sectors of the Nile Valley of Northern Sudan dedicated to the exploration of human-environment interactions during the middle and late Holocene. This part of the Nile corridor contains a rich cultural record and an exceptionally well preserved Holocene fluvial archive. A distinctive feature of these records is the variety of evidence for interaction between desert and river over a range of spatial and temporal scales. This interaction presented both challenges and opportunities for its ancient inhabitants. This paper will present evidence for large-scale landscape changes driven by shifts in global climate. It will also show how we have integrated the archaeological and geological records in the Northern Dongola Reach and at Amara West - where long-term field projects led by archaeologists from the British Museum have recognised the importance of a sustained commitment to interdisciplinary research to achieve a fully integrated geoarchaeological approach across a range of scales. The former project is a large-scale landscape survey with multiple sites across an 80 km reach of the Nile whilst the latter has a strong focus on a single New Kingdom town site and changes in its environmental setting. By combining multiple archaeological and geological datasets - and pioneering the use of OSL dating and strontium isotope analysis in the Desert Nile - we have developed a new understanding of human responses to Holocene climate and landscape change in this region. Renfrew, C. (1976) Archaeology and the earth sciences. In: D.A. Davidson and M.I. Shackley (eds) Geoarchaeology: Earth Science and the Past, Duckworth, London, 1-5.

  15. Ecology of West Nile Virus in North America

    PubMed Central

    Reisen, William K.

    2013-01-01

    The introduction, dispersal and establishment of West Nile virus in North America were reviewed, focusing on factors that may have enhanced receptivity and enabled the invasion process. The overwintering persistence of this tropical virus within temperate latitudes was unexpected, but was key in the transition from invasion to endemic establishment. The cascade of temporal events allowing sporadic amplification to outbreak levels was discussed within a future perspective. PMID:24008376

  16. Widespread West Nile virus activity, eastern United States, 2000.

    PubMed

    Marfin, A A; Petersen, L R; Eidson, M; Miller, J; Hadler, J; Farello, C; Werner, B; Campbell, G L; Layton, M; Smith, P; Bresnitz, E; Cartter, M; Scaletta, J; Obiri, G; Bunning, M; Craven, R C; Roehrig, J T; Julian, K G; Hinten, S R; Gubler, D J

    2001-01-01

    In 1999, the U.S. West Nile (WN) virus epidemic was preceded by widespread reports of avian deaths. In 2000, ArboNET, a cooperative WN virus surveillance system, was implemented to monitor the sentinel epizootic that precedes human infection. This report summarizes 2000 surveillance data, documents widespread virus activity in 2000, and demonstrates the utility of monitoring virus activity in animals to identify human risk for infection.

  17. The Nile Delta: climate pacing and vulnerability to Holocene change

    NASA Astrophysics Data System (ADS)

    Marriner, Nick; Flaux, Clément; Morhange, Christophe; Stanley, Jean-Daniel

    2014-05-01

    Deltas are potentially important sentinels to investigate climate-driven changes in palaeohydrology and human impacts, but, paradoxically, have often been overlooked as palaeoclimate records. In this paper, we present two time-series from the Nile Delta to probe both millennial and centennial-scale changes in deltaic hydrogeomorphology over the past 8000 years. In a global Holocene context, the long-term decrease in Nile Delta accretion rates is consistent with insolation-driven changes in the 'monsoon pacemaker', attested throughout the mid-latitude tropics. Using a second record we suggest that, at shorter timescales, many of the major phases of deltaic modification were mediated by climate events linked to El Niño Southern Oscillation- type (ENSO) variability. In the final part of the paper, we propose that following the early to mid-Holocene growth of the Nile's deltaic plain pronounced deltaic erosion is first recorded after ~4000 years ago, the corollaries of falling sediment supply and an intensification of anthropogenic impacts from the Pharaonic period onwards. The study highlights the importance of the world's deltas as sensitive archives to investigate Holocene geosystem responses to climate change, risks and hazards, and societal interaction.

  18. Incorporation of conjugated fatty acids into Nile tilapia (Oreochromis niloticus).

    PubMed

    Bonafé, Elton G; de Figueiredo, Luana C; Martins, Alessandro F; Monteiro, Johny P; Junior, Oscar Os; Canesin, Edmilson A; Maruyama, Swami Arêa; Visentainer, Jesuí V

    2017-08-01

    The aim of this work was to improve the nutritional quality of Nile tilapia meat through enriched diets with conjugated isomers of linolenic acid from tung oil. The transfer process of conjugated fatty acids (CFAs) into fish muscle tissue was evaluated by gas chromatography-flame ionization detection (GC-FID) and easy ambient sonic-spray ionization mass spectrometry (EASI-MS). The results showed that conjugated fatty acids were transferred from enriched diet for muscle tissue of Nile tilapia. Conjugated linoleic acids biosynthesis from conjugated linolenic acids was also observed after 10 days. Other important fatty acids such as docosahexaenoic (DHA), eicosapentaenoic (EPA) and arachidonic (AA) acids were also identified over time; however, DHA showed the highest concentration when compared with EPA and AA compounds. Therefore, the nutritional quality of Nile tilapia was improved through feeding with enriched diets. The ingestion of these fish may contribute to reaching adequate levels of daily CFA consumption. Furthermore, other important substances which play an important role in human metabolism, such as EPA, DHA and AA, can also be ingested together with CFA. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  19. West Nile Virus Surveillance in the Lombardy Region, Northern Italy.

    PubMed

    Chiari, M; Prosperi, A; Faccin, F; Avisani, D; Cerioli, M; Zanoni, M; Bertoletti, M; Moreno, A M; Bruno, R; Monaco, F; Farioli, M; Lelli, D; Lavazza, A

    2015-08-01

    In 2013, the circulation of West Nile virus (WNV) was detected in the Lombardy region and the following year a surveillance programme was activated with the aim of early identification of the viral distribution in mosquitoes and wild birds. A total of 50 959 Culex spp. mosquitoes grouped in six hundred and forty-seven pools as well as 1400 birds were screened by RT-PCR for the presence of West Nile virus leading to the identification of the viral genome in 32 mosquito pools and 13 wild birds. The surveillance was able to detect the WNV circulation on an average of 42 days (CI 95% 29.98-53.86; Student's t-distribution) before the occurrence of human West Nile disease (WND) cases in the same area. These results demonstrate the presence of WNV in the Lombardy region and confirm entomological and wild birds surveillance as an effective measure for the early identification of WNV circulation in infected areas, thus providing a useful and cost-effective tool for the public health authorities in the application of measures to prevent human infection. © 2015 Blackwell Verlag GmbH.

  20. The Influence of Atmospheric Aerosols on Air Quality Status of the Egyptian Nile Delta

    NASA Astrophysics Data System (ADS)

    El-Askary, H. M.; Zakey, A.

    2014-12-01

    Due to the combination of natural and anthropogenic sources of emission over the Nile Delta region, the air quality status is very poor and has a significant health hazards impacts on the population. Here we focused on the optical and chemical characterizations of atmospheric aerosols in the Nile Delta using the online integrated Environmental-Climate Aerosols model (EnvClimA) during a 10 year period 2000-2010. Observations from MODIS and SeaWiFS measurements supplemented by CALIPSO and some ground-based data from AERONET, are used to validate the EnvClimA model and to illustrate the aerosol characteristics and their sources. CALIPSO measurements were used to characterize the vertical structure of aerosols and their shapes (spherical and non-spherical) for major dust storms and biomass burning events. In this study we discussed the synoptic patterns and features, which are associated with either the dust storm or high pollution events. We used MODIS derived aerosol parameters to study seasonal changes in aerosol parameters due to the influence of dust storms, anthropogenic pollution and biomass (crop residue) burning. MODIS derived deep blue AOD provided better representation of aerosol loading over north Africa (Sahara region) along with dark-target AOD and related parameters. AERONET data provided aerosol optical depth, angstrom, fine mode fraction, size fraction, volume, effective radius, refractive index, single scattering albedo, and radiative forcing during different seasons dominated by dust storms, anthropogenic pollution and biomass burning (black cloud phenomena). The results indicated that the observed AOD decreases in the summer and increases again in the fall due to agricultural burning events. Ground-based AERONET data support the "Dark Product" MODIS retrievals, as they typically show a fall peak in the 500 nm region. The number of dust distribution frequencies over Egypt has more frequency in the southeast and northwest of Egypt (5-7.5 days

  1. Longitudinal studies of West Nile virus infection in avians, Yucatán State, México.

    PubMed

    Farfán-Ale, José A; Blitvich, Bradley J; Loroño-Pino, María A; Marlenee, Nicole L; Rosado-Paredes, Elsy P; García-Rejón, Julián E; Flores-Flores, Luis F; Chulim-Perera, Luis; López-Uribe, Mildred; Pérez-Mendoza, Gerardo; Sánchez-Herrera, Ingrid; Santamaría, Waldemar; Moo-Huchim, Jose; Gubler, Duane J; Cropp, Bruce C; Calisher, Charles H; Beaty, Barry J

    2004-01-01

    Following the introduction of West Nile virus (WNV) into North America in 1999, surveillance for evidence of infection with this virus in migratory and resident birds was established in Yucatán State, México in March 2000. Overall, 8611 birds representing 182 species and 14 orders were captured and assayed for antibodies to WNV. Of these, 5066 (59%) birds were residents and 3545 (41%) birds were migrants. Twenty-one (0.24%) birds exhibited evidence of flavivirus infection. Of these, 8 birds had antibodies to WNV by epitope-blocking enzyme-linked immunosorbent assay. Five (0.06%) birds (gray catbird, brown-crested flycatcher, rose-breasted grosbeak, blue bunting and indigo bunting) were confirmed to have WNV infections by plaque reduction neutralization test. The WNV-infected birds were sampled in December 2002 and January 2003. The brown-crested flycatcher and blue bunting presumably were resident birds; the other WNV seropositive birds were migrants. These data provide evidence of WNV transmission among birds in the Yucatán Peninsula.

  2. The Blue Marble

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This spectacular Moderate Resolution Imaging Spectroradiometer (MODIS) 'blue marble' image is based on the most detailed collection of true-color imagery of the entire Earth to date. Using a collection of satellite-based observations, scientists and visualizers stitched together months of observations of the land surface, oceans, sea ice, and clouds into a seamless, true-color mosaic of every square kilometer (.386 square mile) of our planet. Most of the information contained in this image came from MODIS, illustrating MODIS' outstanding capacity to act as an integrated tool for observing a variety of terrestrial, oceanic, and atmospheric features of the Earth. The land and coastal ocean portions of this image is based on surface observations collected from June through September 2001 and combined, or composited, every eight days to compensate for clouds that might block the satellite's view on any single day. Global ocean color (or chlorophyll) data was used to simulate the ocean surface. MODIS doesn't measure 3-D features of the Earth, so the surface observations were draped over topographic data provided by the U.S. Geological Survey EROS Data Center. MODIS observations of polar sea ice were combined with observations of Antarctica made by the National Oceanic and Atmospheric Administration's AVHRR sensor-the Advanced Very High Resolution Radiometer. The cloud image is a composite of two days of MODIS imagery collected in visible light wavelengths and a third day of thermal infra-red imagery over the poles. A large collection of imagery based on the blue marble in a variety of sizes and formats, including animations and the full (1 km) resolution imagery, is available at the Blue Marble page. Image by Reto Stockli, Render by Robert Simmon. Based on data from the MODIS Science Team

  3. The Blue Marble

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This spectacular Moderate Resolution Imaging Spectroradiometer (MODIS) 'blue marble' image is based on the most detailed collection of true-color imagery of the entire Earth to date. Using a collection of satellite-based observations, scientists and visualizers stitched together months of observations of the land surface, oceans, sea ice, and clouds into a seamless, true-color mosaic of every square kilometer (.386 square mile) of our planet. Most of the information contained in this image came from MODIS, illustrating MODIS' outstanding capacity to act as an integrated tool for observing a variety of terrestrial, oceanic, and atmospheric features of the Earth. The land and coastal ocean portions of this image is based on surface observations collected from June through September 2001 and combined, or composited, every eight days to compensate for clouds that might block the satellite's view on any single day. Global ocean color (or chlorophyll) data was used to simulate the ocean surface. MODIS doesn't measure 3-D features of the Earth, so the surface observations were draped over topographic data provided by the U.S. Geological Survey EROS Data Center. MODIS observations of polar sea ice were combined with observations of Antarctica made by the National Oceanic and Atmospheric Administration's AVHRR sensor-the Advanced Very High Resolution Radiometer. The cloud image is a composite of two days of MODIS imagery collected in visible light wavelengths and a third day of thermal infra-red imagery over the poles. A large collection of imagery based on the blue marble in a variety of sizes and formats, including animations and the full (1 km) resolution imagery, is available at the Blue Marble page. Image by Reto Stockli, Render by Robert Simmon. Based on data from the MODIS Science Team

  4. The Spanish Blue Division

    DTIC Science & Technology

    2005-03-18

    the German North Army Group. WORD COUNT=5933 20 ENDNOTES 1 Torres, Francisco. La Divisi6n Azul50 AFos Despu6s. Madrid: Editorial Fuerza Nueva , 1991,31...osDespu6s. Madrid: Editorial Fuerza Nueva , 1991,47. ’ Kleinfield, Gerald R. and Tambs, Lewis A. La Divisi6n espatjola de Hitler. Madrid: Editorial San Martin...1983, 25. ’ Torres, Francisco. La Divisi6n Azu150AiosDespu6s. Madrid: Editorial Fuerza Nueva , 1991,53 6 The Division was popularly known as the Blue

  5. Keratoglobus and blue sclera.

    PubMed

    Biglan, A W; Brown, S I; Johnson, B L

    1977-02-01

    Five patients from two families had similar features including keratoglobus, blue scleras, hyperextensibility of the hand, wrist, and ankle joints, sensorineural conduction hearing alterations, and mottling of the teeth. Keratoglobus had been observed in all patients at, or shortly after, birth. Corneal perforations developed in seven of the ten eyes after minimal trauma. Repair of these perforations was complicated by the extremely thin corneas and six eyes had to be either enucleated or eviscerated. Histopathological examination of two of the enucleated eyes showed the corneal stromas of both eyes to be estremely thin, Bowman's membrane was absent, and Descemet's membrane was unusually thick. This condition has an autosomal-recessive inheritance pattern.

  6. Blue upconversion thulium laser

    NASA Astrophysics Data System (ADS)

    Nguyen, Dinh C.; Faulkner, George E.; Weber, Michael E.; Dulick, Michael

    1990-04-01

    We report a blue emission upconversion solid-state laser based on Tm3+:YLF. Under double resonance excitation at 780.8 nm (near-ir) and 648.8 nm (red), the Tm3+ ion is sequentially excited from the 3H6 ground state to the 1D2 excited state through the 3H4 intermediate level. The laser output at 450 and 453 nm corresponds to the 1D2 -> 3F4 transitions of Tm3+ ions in YLF.

  7. Wetland vegetation in Manzala lagoon, Nile Delta coast, Egypt: Rapid responses of pollen to altered nile hydrology and land use

    USGS Publications Warehouse

    Bernhardt, C.E.; Stanley, J.-D.; Horton, B.P.

    2011-01-01

    The pollen record in a sediment core from Manzala lagoon on the Nile delta coastal margin of Egypt, deposited from ca. AD 1860 to 1990, indicates rapid coastal wetland vegetation responses to two primary periods of human activity. These are associated with artificially altered Nile hydrologic regimes in proximal areas and distal sectors located to ???1200 km south of Manzala. Freshwater wetland plants that were dominant, such as Typha and Phragmites, decreased rapidly, whereas in the early 1900s, brackish water wetland species (e.g., Amaranthaceae) increased. This change occurred after closure of the Aswan Low Dam in 1902. The second major modification in the pollen record occurred in the early 1970s, after Aswan High Dam closure from 1965 to 1970, when Typha pollen abundance increased rapidly. Massive population growth occurred along the Nile during the 130 years represented by the core section. During this time, the total volume of lagoon water decreased because of conversion of wetland areas to agricultural land, and input of organic-rich sediment, sewage (municipal, agricultural, industrial), and fertilizer in Manzala lagoon increased markedly. Although the wetland plant community has continued to respond to increasingly intensified and varied human-induced pressures in proximal sectors, the two most marked changes in Manzala pollen best correlate with distal events (i.e., closure of the two dams at Aswan). The study also shows that the two major vegetation changes in Manzala lagoon each occurred less than 10 years after closure upriver of the Low and High dams that markedly altered the Nile regime from Upper Egypt to the coast. ?? 2011, the Coastal Education & Research Foundation (CERF).

  8. Explaining and forecasting interannual variability in the flow of the Nile River

    NASA Astrophysics Data System (ADS)

    Siam, M. S.; Eltahir, E. A. B.

    2015-03-01

    This study analyzes extensive data sets collected during the twentieth century and defines four modes of natural variability in the flow of the Nile River, identifying a new significant potential for improving predictability of floods and droughts. Previous studies have identified a significant teleconnection between the Nile flow and the eastern Pacific Ocean. El Niño-Southern Oscillation (ENSO) explains about 25% of the interannual variability in the Nile flow. Here, this study identifies a region in the southern Indian Ocean, with a similarly strong teleconnection to the Nile flow. Sea surface temperature (SST) in the region (50-80° E and 25-35° S) explains 28% of the interannual variability in the flow of the Nile River and, when combined with the ENSO index, the explained variability of the flow of the Nile River increases to 44%. In addition, during those years with anomalous SST conditions in both oceans, this study estimates that indices of the SSTs in the Pacific and Indian oceans can collectively explain up to 84% of the interannual variability in the flow of the Nile. Building on these findings, this study uses the classical Bayesian theorem to develop a new hybrid forecasting algorithm that predicts the Nile flow based on global model predictions of indices of the SST in the eastern Pacific and southern Indian oceans.

  9. Explaining and Forecasting Interannual Variability in the Flow of the Nile River

    NASA Astrophysics Data System (ADS)

    Eltahir, E. A.; Siam, M.

    2013-12-01

    The natural interannual variability in the flow of Nile River had a significant impact on the ancient civilizations and cultures that flourished on the banks of the river. Here, we analyze extensive data sets collected during the 20th century and define four modes of natural variability in the flow of Nile River, identifying a new significant potential for improving predictability of floods and droughts. Previous studies have identified a significant teleconnection between the Nile flow and the Eastern Pacific Ocean. El Niño-Southern Oscillation (ENSO) explains about 25% of the interannual variability in the Nile flow. Here, we identify, for the first time, a region in the southern Indian Ocean with similarly strong teleconnection to the Nile flow. Sea Surface Temperature (SST) in the region (60oE-90oE and 25oS-35oS) explains 28% of the interannual variability in the Nile flow. During those years with anomalous SST conditions in both Oceans, we estimate that indices of the SSTs in the Pacific and Indian Oceans can collectively explain up to 84% of the interannual variability in the flow of Nile. Building on these findings, we use classical Bayesian theorem to develop a new hybrid forecasting algorithm that predicts the Nile flow based on indices of the SST in the Eastern Pacific and Southern Indian Oceans.

  10. Earth view over Egypt and the Nile River taken during STS-121

    NASA Image and Video Library

    2006-07-04

    STS121-334-026 (4-17 July 2006) --- This photo, featuring an easterly view of the Nile River, the Nile River Delta, Sinai Peninsula, the Suez Canal, Red Sea and part of the Mediterranean Sea, was taken by one of the STS-121 crewmembers aboard the Space Shuttle Discovery. Cairo, Egypt, can be seen at far right.

  11. Clinical West Nile virus infection in 2 horses in western Canada.

    PubMed

    Abutarbush, Sameeh M; O'Connor, Brendan P; Clark, Chris; Sampieri, Francesca; Naylor, Jonathan M

    2004-04-01

    Two horses had a history of ataxia and weakness or recumbency. One recovered and was diagnosed with West Nile virus (WNV) infection by serologic testing. The other was euthanized; it had meningoencephalomyelitis, WNV was detected by polymerase chain reaction. West Nile virus infection is an emerging disease. Year 2002 is the first year in which cases have been seen in Saskatchewan.

  12. Clinical West Nile virus infection in 2 horses in western Canada

    PubMed Central

    2004-01-01

    Abstract Two horses had a history of ataxia and weakness or recumbency. One recovered and was diagnosed with West Nile virus (WNV) infection by serologic testing. The other was euthanized; it had meningoencephalomyelitis, WNV was detected by polymerase chain reaction. West Nile virus infection is an emerging disease. Year 2002 is the first year in which cases have been seen in Saskatchewan. PMID:15144104

  13. Identification and expression profiles of multiple genes in Nile tilapia in response to bacterial infections

    USDA-ARS?s Scientific Manuscript database

    To understand the molecular mechanisms involved in response of Nile tilapia (Oreochromis niloticus) to bacterial infection, suppression subtractive cDNA hybridization technique was used to identify upregulated genes in the posterior kidney of Nile tilapia at 6h post infection with Aeromonas hydrophi...

  14. Explaining and forecasting interannual variability in the flow of the Nile River

    NASA Astrophysics Data System (ADS)

    Siam, M. S.; Eltahir, E. A. B.

    2014-05-01

    The natural interannual variability in the flow of Nile River had a significant impact on the ancient civilizations and cultures that flourished on the banks of the river. This is evident from stories in the Bible and Koran, and from the numerous Nilometers discovered near ancient temples. Here, we analyze extensive data sets collected during the 20th century and define four modes of natural variability in the flow of Nile River, identifying a new significant potential for improving predictability of floods and droughts. Previous studies have identified a significant teleconnection between the Nile flow and the Eastern Pacific Ocean. El Niño-Southern Oscillation (ENSO) explains about 25% of the interannual variability in the Nile flow. Here, we identify, for the first time, a region in the southern Indian Ocean with similarly strong teleconnection to the Nile flow. Sea Surface Temperature (SST) in the region (50-80° E and 25-35° S) explains 28% of the interannual variability in the Nile flow. During those years with anomalous SST conditions in both Oceans, we estimate that indices of the SSTs in the Pacific and Indian Oceans can collectively explain up to 84% of the interannual variability in the flow of Nile. Building on these findings, we use classical Bayesian theorem to develop a new hybrid forecasting algorithm that predicts the Nile flow based on global models predictions of indices of the SST in the Eastern Pacific and Southern Indian Oceans.

  15. West Nile virus infection among humans, Texas, USA, 2002-2011.

    PubMed

    Nolan, Melissa S; Schuermann, Jim; Murray, Kristy O

    2013-01-01

    We conducted an epidemiologic analysis to document West Nile virus infections among humans in Texas, USA, during 2002-2011. West Nile virus has become endemic to Texas; the number of reported cases increased every 3 years. Risk for infection was greatest in rural northwestern Texas, where Culex tarsalis mosquitoes are the predominant mosquito species.

  16. Edwardsiella ictaluri as the causative agent of mortality in cultured Nile tilapia

    USDA-ARS?s Scientific Manuscript database

    Edwardsiella ictaluri was consistently isolated from the spleens, livers, and head kidneys of diseased Nile tilapia Oreochromis niloticus from a farm experiencing mortality events in several culture ponds. We describe the first published outbreak of E. ictaluri–induced Edwardsiellosis in Nile tilapi...

  17. Lake Nasser on Nile River in Egypt as seen from the Apollo 7 spacecraft

    NASA Technical Reports Server (NTRS)

    1968-01-01

    Lake Nasser on the Nile River in southeastern United Arab Republic (Egypt) as seen from the Apollo 7 spacecraft during its 10th revolution of the earth. Photographed from an altitude of 130 nautical miles, at ground elapsed time of 14 hours and 56 minutes. Lake Nasser was created by the contruction of the Aswan Dam on the Nile.

  18. Lake Nasser on Nile River in Egypt as seen from the Apollo 7 spacecraft

    NASA Image and Video Library

    1968-10-12

    Lake Nasser on the Nile River in southeastern United Arab Republic (Egypt) as seen from the Apollo 7 spacecraft during its 10th revolution of the earth. Photographed from an altitude of 130 nautical miles, at ground elapsed time of 14 hours and 56 minutes. Lake Nasser was created by the contruction of the Aswan Dam on the Nile.

  19. Blue ocean leadership.

    PubMed

    Kim, W Chan; Mauborgne, Renée

    2014-05-01

    Ten years ago, two INSEAD professors broke ground by introducing "blue ocean strategy," a new model for discovering uncontested markets that are ripe for growth. In this article, they apply their concepts and tools to what is perhaps the greatest challenge of leadership: closing the gulf between the potential and the realized talent and energy of employees. Research indicates that this gulf is vast: According to Gallup, 70% of workers are disengaged from their jobs. If companies could find a way to convert them into engaged employees, the results could be transformative. The trouble is, managers lack a clear understanding of what changes they could make to bring out the best in everyone. Here, Kim and Mauborgne offer a solution to that problem: a systematic approach to uncovering, at each level of the organization, which leadership acts and activities will inspire employees to give their all, and a process for getting managers throughout the company to start doing them. Blue ocean leadership works because the managers' "customers"-that is, the people managers oversee and report to-are involved in identifying what's effective and what isn't. Moreover, the approach doesn't require leaders to alter who they are, just to undertake a different set of tasks. And that kind of change is much easier to implement and track than changes to values and mind-sets.

  20. A GIS tool to estimate West Nile virus risk based on a degree-day model.

    PubMed

    Zou, Li; Miller, Scott N; Schmidtmann, Edward T

    2007-06-01

    West Nile virus (Flaviviridae: Flavivirus) is a serious infectious disease that recently spread across the North America continent. A spatial analysis tool was developed on the ArcMap 9.x platform to estimate potential West Nile virus activity using a spatially explicit degree-day model. The model identifies when the virus Extrinsic Incubation Period (EIP) is completed within the vector longevity during mid-summer months. The EIP is treated as a threshold indicator of the potential for virus emergence and activity. Comparing the number of West Nile virus cases in Wyoming reported from 2003 to 2005 with model results, actual cases and predicted events of West Nile virus activity match relatively well. The model represents a useful method for estimating potential West Nile virus activity in a large spatial scale.

  1. Nile red: Alternative to physical developer for the detection of latent fingermarks on wet porous surfaces?

    PubMed

    Braasch, Karl; de la Hunty, Mackenzie; Deppe, Janina; Spindler, Xanthe; Cantu, Antonio A; Maynard, Philip; Lennard, Chris; Roux, Claude

    2013-07-10

    This paper describes the application of a luminescent lipid stain, nile red, for the development of latent fingermarks on porous surfaces. An optimised formulation is presented that provides rapid development of latent fingermarks on porous surfaces that are or have been wet. A comparison with physical developer (PD), the method of choice to enhance such fingermarks, indicated that nile red was a simpler and more stable technique for the development of fingermarks. The nile red formulation showed similar performance to PD across a range of substrates and ageing conditions, although PD still showed greater sensitivity on five-year-old examination booklets used in a pseudo-operational study. The pseudo-operational trial also indicated that nile red consistently developed different fingermarks to those enhanced by PD, suggesting that it preferentially targets a different fraction of the latent fingermark deposit. Significantly, the compatibility of nile red in a detection sequence with indanedione-zinc, ninhydrin and PD is reported.

  2. Three-dimensional modeling of blue jets and blue starters

    NASA Astrophysics Data System (ADS)

    Pasko, V. P.; George, J. J.

    2001-12-01

    Blue jets are narrow cones of blue light propagating upward from the apparent cloud tops at speeds of the order of 100 km/s to a terminal altitude of about 40 km [Wescott et al., GRL, 22, 1209, 1995]. Blue starters are distinguished from blue jets by a much lower terminal altitude. They protrude upward from the cloud top (17-18 km) to a maximum 25.5 km in altitude [Wescott et al., GRL, 23, 2153, 1996]. It has recently been suggested that blue jets correspond qualitatively to the development of the streamer zone of a positive leader and therefore should be filled with a branching structure of streamer channels [Petrov and Petrova, Tech. Phys., 44, 472, 1999]. In our talk we will discuss the physical concept proposed by Petrov and Petrova [1999] as well as will demonstrate a role of blue jets and blue starters in the large-scale atmospheric electric circuit. We will also discuss specific physical reasons and required circumstances for occurrence of blue jets and starters above thundercloud tops and will support our arguments with results from a new three-dimensional model. The model simulates the propagation of branching streamer channels constituting blue jets and starters as a three dimensional growth of fractal trees in a self-consistent electric field created by thundercloud charges. The model is based on a phenomenological probabilistic approach proposed in [Niemeyer et al., IEEE Trans. Electr. Insul., 24, 309, 1989] and is a straightforward expansion of the previously developed two-dimensional version [Pasko et al., GRL, 27, 497, 2000]. The model results indicate that blue jets and starters can be formed by a fast ( ~1 sec) accumulation of 110-150 C of positive thundercloud charge distributed in a volume with effective radius 3 km near the cloud top at 15 km. The obtained results closely resemble characteristics of blue jets and blue starters observed by Wescott et al. [1995; 1996] in terms of their altitude extents, transverse dimensions and conical structure

  3. Neuropsychological Impact of West Nile Virus Infection: An Extensive Neuropsychiatric Assessment of 49 Cases in Canada.

    PubMed

    Samaan, Zainab; McDermid Vaz, Stephanie; Bawor, Monica; Potter, Tammy Hlywka; Eskandarian, Sasha; Loeb, Mark

    2016-01-01

    West Nile virus emerged as an important human pathogen in North America and continues to pose a risk to public health. It can cause a highly variable range of clinical manifestations ranging from asymptomatic to severe illness. Neuroinvasive disease due to West Nile virus can lead to long-term neurological deficits and psychological impairment. However, these deficits have not been well described. The objective of this study was to characterize the neuropsychological manifestations of West Nile virus infection with a focus on neuroinvasive status and time since infection. Patients from Ontario Canada with a diagnosis of neuroinvasive disease (meningitis, encephalitis, or acute flaccid paralysis) and non-neuroinvasive disease who had participated in a cohort study were enrolled. Clinical and laboratory were collected, as well as demographics and medical history. Cognitive functioning was assessed using a comprehensive battery of neuropsychological tests. Data from 49 individuals (32 with West Nile fever and 17 with West Nile neuroinvasive disease) were included in the present cross-sectional analysis. Patterns of neuropsychological impairment were comparable across participants with both neuroinvasive and non-neuroinvasive West Nile virus infection on all cognitive measures. Neuropsychiatric impairment was also observed more frequently at two to four years post-infection compared to earlier stages of illness. Our data provide objective evidence for cognitive difficulties among patients who were infected with West Nile virus; these deficits appear to manifest regardless of severity of West Nile virus infection (West Nile fever vs. West Nile neuroinvasive disease), and are more prevalent with increasing illness duration (2-4 years vs. 1 month). Data from this study will help inform patients and healthcare providers about the expected course of recovery, as well as the need to implement effective treatment strategies that include neuropsychological interventions.

  4. Pluto’s Blue Haze

    NASA Image and Video Library

    The sky on Pluto is blue! Kind of. This is Pluto in an Minute. So it’s not exactly the case that the sky on Pluto is blue, rather, what the New Horizons science team has found in recent images do...

  5. Blue Origin Facility - Construction Progress

    NASA Image and Video Library

    2017-03-21

    Construction is progressing on Blue Origin's 750,000-square-foot facility being built at Exploration Park on NASA Kennedy Space Center property in Florida. Blue Origin will use the factory to manufacture its two-stage super-heavy-lift New Glenn launch vehicle and launch the vehicles from Space Launch Complex 46 at Cape Canaveral Air Force Station.

  6. Thermal preference predicts animal personality in Nile tilapia Oreochromis niloticus.

    PubMed

    Cerqueira, Marco; Rey, Sonia; Silva, Tome; Featherstone, Zoe; Crumlish, Margaret; MacKenzie, Simon

    2016-09-01

    Environmental temperature gradients provide habitat structure in which fish orientate and individual thermal choice may reflect an essential integrated response to the environment. The use of subtle thermal gradients likely impacts upon specific physiological and behavioural processes reflected as a suite of traits described by animal personality. In this study, we examine the relationship between thermal choice, animal personality and the impact of infection upon this interaction. We predicted that thermal choice in Nile tilapia Oreochromis niloticus reflects distinct personality traits and that under a challenge individuals exhibit differential thermal distribution. Nile tilapia were screened following two different protocols: 1) a suite of individual behavioural tests to screen for personality and 2) thermal choice in a custom-built tank with a thermal gradient (TCH tank) ranging from 21 to 33 °C. A first set of fish were screened for behaviour and then thermal preference, and a second set were tested in the opposite fashion: thermal then behaviour. The final thermal distribution of the fish after 48 h was assessed reflecting final thermal preferendum. Additionally, fish were then challenged using a bacterial Streptococcus iniae model infection to assess the behavioural fever response of proactive and reactive fish. Results showed that individuals with preference for higher temperatures were also classified as proactive with behavioural tests and reactive contemporaries chose significantly lower water temperatures. All groups exhibited behavioural fever recovering personality-specific thermal preferences after 5 days. Our results show that thermal preference can be used as a proxy to assess personality traits in Nile tilapia and it is a central factor to understand the adaptive meaning of animal personality within a population. Importantly, response to infection by expressing behavioural fever overrides personality-related thermal choice.

  7. Acute hypoxia-reperfusion triggers immunocompromise in Nile tilapia.

    PubMed

    Choi, K; Lehmann, D W; Harms, C A; Law, J M

    2007-06-01

    Inadequate dissolved oxygen in the aquatic environment is a well-established cause of fish morbidity and mortality. The specific effects of hypoxia on immune function in fish, however, are not well characterized. In this study, the effects of acute hypoxia followed by reoxygenation (rapid tissue reperfusion) as a source of immunocompromise in Nile tilapia Oreochromis niloticus were investigated. Using a precision apparatus developed in our laboratory for hypoxia exposures, a series of assays of increasing specificity for immune function were performed on acutely hypoxia-stressed Nile tilapia: tier I consisted of histopathology, tier II of hematology, plasma chemistry, and determining cortisol concentration, and tier III of determining the phagocytic index and analyzing the expression of the cytokines transforming growth factor-beta (TGF-beta) and interleukin-1beta (IL-1beta). Nile tilapia were exposed to 7% oxygen saturation for 96 h, then tank water was rapidly reoxygenated. Sampling intervals were 48 and 96 h during hypoxia and 12 and 84 h during reperfusion. Histopathology showed no remarkable microscopic abnormalities in lymphoid or other tissues. Lymphopenia and neutrophilia were observed in peripheral blood. Plasma total protein, partial pressure of oxygen, and oxygen saturation were decreased in response to hypoxia. Plasma lipase decreased in response to hypoxia but returned to normal during reperfusion. Phagocytic capability and the phagocytic index decreased during hypoxia and 12 h reperfusion, whereas these values were recovered by 84 h reperfusion. The TGF-beta transcription continued to increase during the exposures, the greatest production being at 12 h reperfusion, whereas IL-1beta transcription decreased in response to hypoxia and reperfusion. We conclude that acute hypoxia triggered an overall downregulation of the immune system in the test fish. This suggests a possible factor in the pathogenesis of disease outbreaks in fish in which repeated

  8. West Nile Virus in Europe and Safety of Blood Transfusion

    PubMed Central

    Pisani, Giulio; Cristiano, Karen; Pupella, Simonetta; Liumbruno, Giancarlo Maria

    2016-01-01

    Summary West Nile virus (WNV) has become an increasing issue in the transfusion setting since 2002, when it was firstly shown in the USA that it can be transmitted through blood transfusion. Since then, several precautionary measures have been introduced in Europe in order to reduce the possible risk of transmission via transfusion/solid organ transplantation. In addition, the epidemiological surveillance has been tightened and the network for communication of human WNV cases strengthened. This review will focus on WNV circulation and the safety of blood in Europe. PMID:27403087

  9. Nile River, Lake Nasser, Aswan High Dam, Egypt

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Aswan High Dam, 2.5 miles across and 364 feet high, (24.0N, 33.0E) completed in 1971, was constructed to supply cheap hydroelectric power to both Egypt and Sudan by impounding, controling and regulating the flood waters of the Nile River in Lake Nasser, the world's second largest artifical lake. The lake extends over 500 miles in length, covers an area of some 2,000 square miles and is as much as 350 feet deep at the face of the dam.

  10. West Nile virus in the British Virgin Islands.

    PubMed

    Anthony, S J; Garner, M M; Palminteri, L; Navarrete-Macias, I; Sanchez-Leon, M D; Briese, T; Daszak, P; Lipkin, W I

    2014-06-01

    West Nile virus (WNV) first emerged in the US in 1999 and has since spread across the Americas. Here, we report the continued expansion of WNV to the British Virgin Islands following its emergence in a flock of free-roaming flamingos. Histologic review of a single chick revealed lesions consistent with WNV infection, subsequently confirmed with PCR, immunohistochemistry and in situ hybridization. Full genome analysis revealed 99% sequence homology to strains circulating in the US over the past decade. This study highlights the need for rapid necropsy of wild bird carcasses to fully understand the impact of WNV on wild populations.

  11. Nile Red Staining of Neutral Lipids in Yeast.

    PubMed

    Rostron, Kerry Ann; Lawrence, Clare Louise

    2017-01-01

    Determination of cellular neutral lipid levels in yeast is important for both the biotechnology industry and biomedical research. However, many of the currently available methods are labor intensive and time consuming. Here we describe a rapid and repeatable method for the detection of neutral lipids, which can be utilized in both oleaginous and non-oleaginous yeast species. The method utilizes the fluorescent dye, Nile red, which enables neutral lipid levels to either be visualized via microscopy or quantified using a 96-well plate assay.

  12. Chronic West Nile virus infection in kea (Nestor notabilis).

    PubMed

    Bakonyi, Tamás; Gajdon, Gyula K; Schwing, Raoul; Vogl, Wolfgang; Häbich, Annett-Carolin; Thaller, Denise; Weissenböck, Herbert; Rudolf, Ivo; Hubálek, Zdenek; Nowotny, Norbert

    2016-02-01

    Six kea (Nestor notabilis) in human care, naturally infected with West Nile virus (WNV) lineage 2 in Vienna, Austria, in 2008, developed mild to fatal neurological signs. WNV RNA persisted and the virus evolved in the birds' brains, as demonstrated by (phylo)genetic analyses of the complete viral genomes detected in kea euthanized between 2009 and 2014. WNV antibodies persisted in the birds, too. Chronic WNV infection in the brain might contribute to the circulation of the virus through oral transmission to predatory birds. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. The resurgence of lymphatic filariasis in the Nile delta.

    PubMed Central

    Harb, M.; Faris, R.; Gad, A. M.; Hafez, O. N.; Ramzy, R.; Buck, A. A.

    1993-01-01

    A study of 325,000 residents of 314 villages in six governorates of the Nile delta area of Egypt revealed that the prevalence of lymphatic filariasis increased from < 1% in 1965 to > 20% in 1991, especially in the governorates of Qalyubiya, Monufiya, Dakhaliya, and Giza. The distribution of the communites with endemic filariasis is focal. Clusters of villages with high prevalences are surrounded by others in which the disease is absent, although their environmental, social, and agricultural features appear similar. The article analyses why the significant decline in filariasis between 1945 and 1965 in Egypt has been followed by a resurgence of the disease. PMID:8440037

  14. West Nile virus in wild resident birds, Southern France, 2004.

    PubMed

    Jourdain, E; Schuffenecker, I; Korimbocus, J; Reynard, S; Murri, S; Kayser, Y; Gauthier-Clerc, M; Sabatier, P; Zeller, H G

    2007-01-01

    An equine West Nile virus (WNV) outbreak occurred in 2004 in the Camargue, a wetland area in the south of France where the virus was first reported in 1962 and re-emerged in 2000. WNV neutralizing antibodies were detected in resident birds and two isolates from a House Sparrow (Passer domesticus) and a Common Magpie (Pica pica) were completely sequenced. Phylogenetic analyses revealed that these isolates are closely related to strains previously found in horses in southern Europe and North Africa. More extensive investigation is required to determine whether WNV has been re-introduced or has become endemic in the Camargue.

  15. Temporal and spatial patterns of West Nile virus transmission in Saginaw County, Michigan, 2003-2006.

    PubMed

    Chuang, Ting-Wu; Knepper, Randall G; Stanuszek, William W; Walker, Edward D; Wilson, Mark L

    2011-09-01

    The dynamics of West Nile virus (family Flaviviridae, genus Flavivirus, WNV) infection in mosquitoes, sentinel pheasants, and wild dead birds were evaluated during 2003-2006 in Saginaw Co., MI. Mosquitoes were collected by New Jersey Light Traps at 22 sites during May-September, pooled by species and sample location, and tested for presence of WNV RNA by using a real-time reverse transcription-polymerase chain reaction assay. Oral swabs from wild dead birds submitted by the public were tested by Vec-Test assay. Sentinel pheasants were bled weekly, and serum was tested for antibodies with an inhibition enzyme immunoassay. In total, 37,225 mosquitoes [Aedes vexans (Meigen), Culex pipiens L., and Culex restuans Theobald] were tested in 5,429 pools, of which 59 (1.1%) were positive. Ae. vexans was most abundant but had a comparatively low infection rate (0.06-2.11) compared with Cx. pipiens (1.75-4.59) and Cx. restuans (1.22-15.67). Mosquito abundances were temporally related to variations in 2-wk average weather variables. Infected dead crows appeared earlier each transmission season than blue jays, but infection prevalence for both peaked approximately mid-August. Space-time clusters were found in different locations each year. Sentinel pheasant seroprevalence was 19.3% (16/83), 12.7% (10/79), and 7.7% (5/65) during 2003-2005, respectively. We demonstrated temporal patterns of WNV activity in corvid birds and Culex spp. mosquitoes during the study period, suggesting virus transmission within an enzootic cycle. Despite the absence of human case reports nearby, this surveillance system demonstrated WNV transmission and possible human risk. Maintained surveillance using more appropriate gravid traps and CDC CO2 light traps could improve sensitivity of vector collection and virus detection.

  16. Impact of introduced Nile tilapia (Oreochromis niloticus) on non-native aquatic ecosystems.

    PubMed

    Vicente, I S T; Fonseca-Alves, C E

    2013-02-01

    The global invasion of non-native aquatic ecosystems by Nile tilapia (Oreochromis niloticus) is well documented and coincides with their increased use as an aquaculture species. Aquaculture can be defined as the farming of fish or other aquatic organisms and it varies considerably in terms of production practices. Generally, freshwater finfish, such as Nile tilapia, are reared in inland ponds (closed systems). However, in several countries, floating cages are increasingly used to rear Nile tilapia in open water bodies. In such systems, escape is inevitable. The Nile tilapia is considered an omnivorous species and it ingests zooplankton, phytoplankton, or debris present in rivers. As a consequence, the release of Nile tilapia into non-native aquatic ecosystems may result in competition for food and space, thereby damaging native species. The wide environmental tolerance and high reproductive rate of Nile tilapia facilitate its use for aquaculture, but also render the species highly invasive. Here, we review the high frequency of Nile tilapia in non-native biodiversity and indicate the existence of the species under feral conditions in every country in which it has been introduced through farming systems.

  17. Was Lates Late? A Null Model for the Nile Perch Boom in Lake Victoria

    PubMed Central

    Downing, Andrea S.; Galic, Nika; Goudswaard, Kees P. C.; van Nes, Egbert H.; Scheffer, Marten; Witte, Frans; Mooij, Wolf M.

    2013-01-01

    Nile perch (Lates niloticus) suddenly invaded Lake Victoria between 1979 and 1987, 25 years after its introduction in the Ugandan side of the lake. Nile perch then replaced the native fish diversity and irreversibly altered the ecosystem and its role to lakeshore societies: it is now a prised export product that supports millions of livelihoods. The delay in the Nile perch boom led to a hunt for triggers of the sudden boom and generated several hypotheses regarding its growth at low abundances – all hypotheses having important implications for the management of Nile perch stocks. We use logistic growth as a parsimonious null model to predict when the Nile perch invasion should have been expected, given its growth rate, initial stock size and introduction year. We find the first exponential growth phase can explain the timing of the perch boom at the scale of Lake Victoria, suggesting that complex mechanisms are not necessary to explain the Nile perch invasion or its timing. However, the boom started in Kenya before Uganda, indicating perhaps that Allee effects act at smaller scales than that of the whole Lake. The Nile perch invasion of other lakes indicates that habitat differences may also have an effect on invasion success. Our results suggest there is probably no single management strategy applicable to the whole lake that would lead to both efficient and sustainable exploitation of its resources. PMID:24204684

  18. Was Lates late? A null model for the Nile perch boom in Lake Victoria.

    PubMed

    Downing, Andrea S; Galic, Nika; Goudswaard, Kees P C; van Nes, Egbert H; Scheffer, Marten; Witte, Frans; Mooij, Wolf M

    2013-01-01

    Nile perch (Lates niloticus) suddenly invaded Lake Victoria between 1979 and 1987, 25 years after its introduction in the Ugandan side of the lake. Nile perch then replaced the native fish diversity and irreversibly altered the ecosystem and its role to lakeshore societies: it is now a prised export product that supports millions of livelihoods. The delay in the Nile perch boom led to a hunt for triggers of the sudden boom and generated several hypotheses regarding its growth at low abundances--all hypotheses having important implications for the management of Nile perch stocks. We use logistic growth as a parsimonious null model to predict when the Nile perch invasion should have been expected, given its growth rate, initial stock size and introduction year. We find the first exponential growth phase can explain the timing of the perch boom at the scale of Lake Victoria, suggesting that complex mechanisms are not necessary to explain the Nile perch invasion or its timing. However, the boom started in Kenya before Uganda, indicating perhaps that Allee effects act at smaller scales than that of the whole Lake. The Nile perch invasion of other lakes indicates that habitat differences may also have an effect on invasion success. Our results suggest there is probably no single management strategy applicable to the whole lake that would lead to both efficient and sustainable exploitation of its resources.

  19. Intraspecific variation in gill morphology of juvenile Nile perch, Lates niloticus, in Lake Nabugabo, Uganda

    USGS Publications Warehouse

    Paterson, Jaclyn A.; Chapman, Lauren J.; Schofield, Pamela J.

    2010-01-01

    Several studies have demonstrated intraspecific variation in fish gill size that relates to variation in dissolved oxygen (DO) availability across habitats. In Lake Nabugabo, East Africa, ecological change over the past 12 years has coincided with a shift in the distribution of introduced Nile perch such that a larger proportion of the population now inhabits waters in or near wetland ecotones where DO is lower than in open waters of the lake. In this study, we compared gill size of juvenile Nile perch between wetland and exposed (open-water) habitats of Lake Nabugabo in 2007, as well as between Nile perch collected in 1996 and 2007. For Nile perch of Lake Nabugabo [<20 cm total length (TL)], there was a significant habitat effect on some gill traits. In general, fish from wetland habitats were characterized by a longer total gill filament length and average gill filament length than conspecifics from exposed habitats. Nile perch collected from wetland areas in 2007 had significantly larger gills (total gill filament length) than Nile perch collected in 1996, but there was no difference detected between Nile perch collected from exposed sites in 2007 and conspecifics collected in 1996.

  20. Interaction of surface water and groundwater in the Nile River basin: isotopic and piezometric evidence

    NASA Astrophysics Data System (ADS)

    Kebede, Seifu; Abdalla, Osman; Sefelnasr, Ahmed; Tindimugaya, Callist; Mustafa, Osman

    2017-05-01

    Past discussions around water-resources management and development in the River Nile basin disregard groundwater resources from the equation. There is an increasing interest around factoring the groundwater resources as an integral part of the Nile Basin water resources. This is hampered by knowledge gap regarding the groundwater resources dynamics (recharge, storage, flow, quality, surface-water/groundwater interaction) at basin scale. This report provides a comprehensive analysis of the state of surface-water/groundwater interaction from the headwater to the Nile Delta region. Piezometric and isotopic (δ18O, δ2H) evidence reveal that the Nile changes from a gaining stream in the headwater regions to mostly a loosing stream in the arid lowlands of Sudan and Egypt. Specific zones of Nile water leakage to the adjacent aquifers is mapped using the two sources of evidence. Up to 50% of the surface-water flow in the equatorial region of the Nile comes from groundwater as base flow. The evidence also shows that the natural direction and rate of surface-water/groundwater interaction is largely perturbed by human activities (diversion, dam construction) particularly downstream of the Aswan High Dam in Egypt. The decrease in discharge of the Nile River along its course is attributed to leakage to the aquifers as well as to evaporative water loss from the river channel. The surface-water/groundwater interaction occurring along the Nile River and its sensitivity to infrastructure development calls for management strategies that account groundwater as an integral part of the Nile Basin resources.

  1. Interaction of surface water and groundwater in the Nile River basin: isotopic and piezometric evidence

    NASA Astrophysics Data System (ADS)

    Kebede, Seifu; Abdalla, Osman; Sefelnasr, Ahmed; Tindimugaya, Callist; Mustafa, Osman

    2016-12-01

    Past discussions around water-resources management and development in the River Nile basin disregard groundwater resources from the equation. There is an increasing interest around factoring the groundwater resources as an integral part of the Nile Basin water resources. This is hampered by knowledge gap regarding the groundwater resources dynamics (recharge, storage, flow, quality, surface-water/groundwater interaction) at basin scale. This report provides a comprehensive analysis of the state of surface-water/groundwater interaction from the headwater to the Nile Delta region. Piezometric and isotopic (δ18O, δ2H) evidence reveal that the Nile changes from a gaining stream in the headwater regions to mostly a loosing stream in the arid lowlands of Sudan and Egypt. Specific zones of Nile water leakage to the adjacent aquifers is mapped using the two sources of evidence. Up to 50% of the surface-water flow in the equatorial region of the Nile comes from groundwater as base flow. The evidence also shows that the natural direction and rate of surface-water/groundwater interaction is largely perturbed by human activities (diversion, dam construction) particularly downstream of the Aswan High Dam in Egypt. The decrease in discharge of the Nile River along its course is attributed to leakage to the aquifers as well as to evaporative water loss from the river channel. The surface-water/groundwater interaction occurring along the Nile River and its sensitivity to infrastructure development calls for management strategies that account groundwater as an integral part of the Nile Basin resources.

  2. Blue bubble in Carina

    NASA Image and Video Library

    2016-02-22

    Sparkling at the centre of this beautiful NASA/ESA Hubble Space Telescope image is a Wolf–Rayet star known as WR 31a, located about 30 000 light-years away in the constellation of Carina (The Keel). The distinctive blue bubble appearing to encircle WR 31a, and its uncatalogued stellar sidekick, is a Wolf–Rayet nebula — an interstellar cloud of dust, hydrogen, helium and other gases. Created when speedy stellar winds interact with the outer layers of hydrogen ejected by Wolf–Rayet stars, these nebulae are frequently ring-shaped or spherical. The bubble — estimated to have formed around 20 000 years ago — is expanding at a rate of around 220 000 kilometres per hour! Unfortunately, the lifecycle of a Wolf–Rayet star is only a few hundred thousand years — the blink of an eye in cosmic terms. Despite beginning life with a mass at least 20 times that of the Sun, Wolf–Rayet stars typically lose half their mass in less than 100 000 years. And WR 31a is no exception to this case. It will, therefore, eventually end its life as a spectacular supernova, and the stellar material expelled from its explosion will later nourish a new generation of stars and planets.

  3. A spattering of blue

    NASA Image and Video Library

    2014-09-08

    Far beyond the stars in the constellation of Leo (The Lion) is irregular galaxy IC 559. IC 559 is not your everyday galaxy. With its irregular shape and bright blue spattering of stars, it is a fascinating galactic anomaly. It may look like sparse cloud, but it is in fact full of gas and dust which is spawning new stars. Discovered in 1893, IC 559 lacks the symmetrical spiral appearance of some of its galactic peers and not does not conform to a regular shape. It is actually classified as a “type Sm” galaxy — an irregular galaxy with some evidence for a spiral structure. Irregular galaxies make up about a quarter of all known galaxies and do not fall into any of the regular classes of the Hubble sequence. Most of these uniquely shaped galaxies were not always so — IC 559 may have once been a conventional spiral galaxy that was then distorted and twisted by the gravity of a nearby cosmic companion. This image, captured by the NASA/ESA Hubble Space Telescope’s Wide Field Camera 3, combines a wide range of wavelengths spanning the ultraviolet, optical, and infrared parts of the spectrum.

  4. Blue metal complex pigments involved in blue flower color

    PubMed Central

    Takeda, Kosaku

    2006-01-01

    The blue pigment of cornflower, protocyanin, has been investigated for a long time, but its precise structure was not entirely explained until recently. The molecular structure of the pigment was recently shown to be a metal complex of six molecules each of anthocyanin and flavone glycoside, with one ferric iron, one magnesium and two calcium ions by X-ray crystallographic analysis. The studies provided the answer to the question posed in the early part of the last century, “why is the cornflower blue and rose red when both flowers contain the same anthocyanin?” This work was achieved on the basis of the results of long years of the studies made by many researchers. In this review, the author focuses on the investigations of the blue metal complex pigments involved in the bluing of flowers, commelinin from Commelina commusis, protocyanin from Centaurea cyanus, protodelphin from Salvia patens and hydrangea blue pigment. PMID:25792777

  5. Blue metal complex pigments involved in blue flower color.

    PubMed

    Takeda, Kosaku

    2006-05-01

    The blue pigment of cornflower, protocyanin, has been investigated for a long time, but its precise structure was not entirely explained until recently. The molecular structure of the pigment was recently shown to be a metal complex of six molecules each of anthocyanin and flavone glycoside, with one ferric iron, one magnesium and two calcium ions by X-ray crystallographic analysis. The studies provided the answer to the question posed in the early part of the last century, "why is the cornflower blue and rose red when both flowers contain the same anthocyanin?" This work was achieved on the basis of the results of long years of the studies made by many researchers. In this review, the author focuses on the investigations of the blue metal complex pigments involved in the bluing of flowers, commelinin from Commelina commusis, protocyanin from Centaurea cyanus, protodelphin from Salvia patens and hydrangea blue pigment.

  6. Pesticide residues and heavy metals in Lake Victoria Nile perch, Lates niloticus, belly flap oil.

    PubMed

    Ogwok, P; Muyonga, J H; Sserunjogi, M L

    2009-05-01

    Oil was extracted from the belly flaps of varied sizes of Nile perch caught from Lake Victoria (Uganda). The oil was analyzed for pesticide residues and heavy metals. Total residual concentration of dichlorodiphenyltrichloroethane, endosulfan, hexachlorocyclohexane, hexachlorobenzene, heptachlor, chlordane, endrin, aldrin and chlorofenvinphos increased significantly (p < 0.05) with fish size. Mercury and lead were detected in most samples while arsenic and cadmium were below detection limits. Nile perch may, therefore, accumulate significant amount of chemical contaminants. Levels of contaminants in Nile perch oil were, in general, within limits considered acceptable by the stringent German Food Law for human consumption.

  7. Experimental infection of raccoons (Procyon lotor) with West Nile virus.

    PubMed

    Root, J Jeffrey; Bentler, Kevin T; Nemeth, Nicole M; Gidlewski, Thomas; Spraker, Terry R; Franklin, Alan B

    2010-10-01

    To characterize the responses of raccoons to West Nile virus (WNV) infection, we subcutaneously exposed them to WNV. Moderately high viremia titers (≤ 10(4.6) plaque forming units [PFU]/mL of serum) were noted in select individuals; however, peak viremia titers were variable and viremia was detectable in some individuals as late as 10 days post-inoculation (DPI). In addition, fecal shedding was prolonged in some animals (e.g., between 6 and 13 DPI in one individual), with up to 10(5.0) PFU/fecal swab detected. West Nile virus was not detected in tissues collected on 10 or 16 DPI, and no histologic lesions attributable to WNV infection were observed. Overall, viremia profiles suggest that raccoons are unlikely to be important WNV amplifying hosts. However, this species may occasionally shed significant quantities of virus in feces. Considering their behavioral ecology, including repeated use of same-site latrines, high levels of fecal shedding could potentially lead to interspecies fecal-oral WNV transmission.

  8. A regional approach to climate adaptation in the Nile Basin

    NASA Astrophysics Data System (ADS)

    Butts, Michael B.; Buontempo, Carlo; Lørup, Jens K.; Williams, Karina; Mathison, Camilla; Jessen, Oluf Z.; Riegels, Niels D.; Glennie, Paul; McSweeney, Carol; Wilson, Mark; Jones, Richard; Seid, Abdulkarim H.

    2016-10-01

    The Nile Basin is one of the most important shared basins in Africa. Managing and developing the water resources within the basin must not only address different water uses but also the trade-off between developments upstream and water use downstream, often between different countries. Furthermore, decision-makers in the region need to evaluate and implement climate adaptation measures. Previous work has shown that the Nile flows can be highly sensitive to climate change and that there is considerable uncertainty in climate projections in the region with no clear consensus as to the direction of change. Modelling current and future changes in river runoff must address a number of challenges; including the large size of the basin, the relative scarcity of data, and the corresponding dramatic variety of climatic conditions and diversity in hydrological characteristics. In this paper, we present a methodology, to support climate adaptation on a regional scale, for assessing climate change impacts and adaptation potential for floods, droughts and water scarcity within the basin.

  9. Masculinization of Nile tilapia (Oreochromis niloticus) by immersion in androgens

    USGS Publications Warehouse

    Gale, W.L.; Fitzpatrick, M.S.; Lucero, M.; Contreras-Sanchez, W.M.; Schreck, C. B.

    1999-01-01

    The use of all-male populations increases the efficiency and feasibility of tilapia aquaculture. The objective of this study was to determine the efficacy of a short-term immersion procedure for masculinizing Nile tilapia (Oreochromis niloticus). Two synthetic androgens were evaluated: 17α-methyldihydrotestosterone (MDHT) and 17α-methyltestosterone (MT). Exposure (3 h) on 10 and again on 13 days post-fertilization to MDHT at 500 μg/1 successfully masculinized fry in all experiments, resulting in 100, 94 and 83 ± 2% males in Experiments 1, 2 and 3, respectively. Immersions in MDHT or MT at 100 μg/1 resulted in significantly skewed sex ratios in Experiments 1 and 3 (MT resulted in 73 and 83 ± 3% males; and MDHT resulted in 72 and 91 ± 1% males) but not in Experiment 2. Immersion in MT at 500 μg/1 only caused masculinization in Experiment 3. Although further research and refinement is needed, immersion of Nile tilapia in MDHT may provide a practical alternative to the use of steroid-treated feed. Furthermore, when compared with current techniques for steroid-induced sex inversion of tilapia, short-term immersion reduces the period of time that workers are exposed to anabolic steroids.

  10. Risk mapping of West Nile virus circulation in Spain, 2015.

    PubMed

    Sánchez-Gómez, Amaya; Amela, Carmen; Fernández-Carrión, Eduardo; Martínez-Avilés, Marta; Sánchez-Vizcaíno, José Manuel; Sierra-Moros, María José

    2017-05-01

    West Nile fever is an emergent disease in Europe. The objective of this study was to conduct a predictive risk mapping of West Nile Virus (WNV) circulation in Spain based on historical data of WNV circulation. Areas of Spain with evidence of WNV circulation were mapped based on data from notifications to the surveillance systems and a literature review. A logistic regression-based spatial model was used to assess the probability of WNV circulation. Data were analyzed at municipality level. Mean temperatures of the period from June to October, presence of wetlands and presence of Special Protection Areas for birds were considered as potential predictors. Two predictors of WNV circulation were identified: higher temperature [adjusted odds ratio (AOR) 2.07, 95% CI 1.82-2.35, p<0.01] and presence of wetlands (3.37, 95% CI 1.89-5.99, p<0.01). Model validations indicated good predictions: area under the ROC curve was 0.895 (95% CI 0.870-0.919) for internal validation and 0.895 (95% CI 0.840-0.951) for external validation. This model could support improvements of WNV risk- based surveillance in Spain. The importance of a comprehensive surveillance for WNF, including human, animal and potential vectors is highlighted, which could additionally result in model refinements. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Experimental Infection of Raccoons (Procyon lotor) with West Nile Virus

    PubMed Central

    Root, J. Jeffrey; Bentler, Kevin T.; Nemeth, Nicole M.; Gidlewski, Thomas; Spraker, Terry R.; Franklin, Alan B.

    2010-01-01

    To characterize the responses of raccoons to West Nile virus (WNV) infection, we subcutaneously exposed them to WNV. Moderately high viremia titers (≤ 104.6 plaque forming units [PFU]/mL of serum) were noted in select individuals; however, peak viremia titers were variable and viremia was detectable in some individuals as late as 10 days post-inoculation (DPI). In addition, fecal shedding was prolonged in some animals (e.g., between 6 and 13 DPI in one individual), with up to105.0 PFU/fecal swab detected. West Nile virus was not detected in tissues collected on 10 or 16 DPI, and no histologic lesions attributable to WNV infection were observed. Overall, viremia profiles suggest that raccoons are unlikely to be important WNV amplifying hosts. However, this species may occasionally shed significant quantities of virus in feces. Considering their behavioral ecology, including repeated use of same-site latrines, high levels of fecal shedding could potentially lead to interspecies fecal-oral WNV transmission. PMID:20889868

  12. Holocene evolution of the northeastern corner of the Nile Delta

    NASA Astrophysics Data System (ADS)

    Sneh, A.; Weissbrod, T.; Ehrlich, A.; Horowitz, A.; Moshkovitz, S.; Rosenfeld, A.

    1986-09-01

    The constructive phase of the modern Nile Delta, as manifested in a 48-m section drilled east of the Suez Canal, commenced in very early Holocene times. Sands rich in marine fauna were deposited in the littoral zone and the shoreline was more than 20 km landward of its present-day position. Subsequently, clays and silts were dumped from the Nile distributaries and the marine faunal spectrum became very limited and brackish. Later in early and middle Holocene times the sediments deposited were rich in freshwater, delta-plain diatoms and pollen and in allochthonous fern spores from the tropics, indicating proximity of a distributary mouth. The middle part of the section (22.5-17.5 m) is very poor in faunal and floral remains; pollen grains from sabkha vegetation are abundant. The environment, which seems lagoonal and slightly hypersaline, is related to the sea regression in middle Holocene times. Euryhaline pelecypods, dating from about 3000 yr B.P., are abundant around the 8-m depth. Upward, there is an increase in pollen grains from sabkhas; the section is poor in diatoms and those present are mostly euryhaline and lagoonal. Allochthonous spores derived from the nearby Pelusiac Branch are abundant. Between 3000 and 2000 yr B.P. the constructive phase of the modern delta terminated and winnowed sands began accreting in front of the delta plain.

  13. West Nile Virus workshop: scientific considerations for tissue donors.

    PubMed

    Brubaker, Scott A; Robert Rigney, P

    2012-08-01

    This report contains selected excerpts, presented as a summary, from a public workshop sponsored by the American Association of Tissue Banks (AATB) held to discuss West Nile Virus (WNV) and scientific considerations for tissue donors. The daylong workshop was held 9 July 2010 at the Ritz-Carlton Hotel at Tyson's Corner in McLean, Virginia, United States (U.S.). The workshop was designed to determine and discuss scientific information that is known, and what is not known, regarding WNV infection and transmission. The goal is to determine how to fill gaps in knowledge of WNV and tissue donation and transplantation by pursuing relevant scientific studies. This information should ultimately support decisions leading to appropriate tissue donor screening and testing considerations. Discussion topics were related to identifying these gaps and determining possible solutions. Workshop participants included subject-matter experts from the U.S. Food and Drug Administration, the Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Health Canada, the Public Health Agency of Canada, AATB-accredited tissue banks including reproductive tissue banks, accredited eye banks of the Eye Bank Association of America, testing laboratories, and infectious disease and organ transplantation professionals. After all presentations concluded, a panel addressed this question: "What are the scientific considerations for tissue donors and what research could be performed to address those considerations?" The slide presentations from the workshop are available at: http://www.aatb.org/2010-West-Nile-Virus-Workshop-Presentations.

  14. West Nile virus activity in Latin America and the Caribbean.

    PubMed

    Komar, Nicholas; Clark, Gary G

    2006-02-01

    West Nile virus (Flavivirus: Flaviviridae; WNV) has spread rapidly throughout the Caribbean Basin since its initial detection there in 2001. This report summarizes our current knowledge of WNV transmission in tropical America. We reviewed the published literature and consulted with key public health officials to obtain unpublished data. West Nile virus infections first appeared in human residents of the Cayman Islands and the Florida Keys in 2001, and in apparently healthy Jamaican birds sampled early in 2002. Serologic evidence of WNV infection in 2002 was detected in horses, chickens and resident free-ranging birds in Guadeloupe, the Dominican Republic, and eastern Mexico. In 2003, WNV spread in Mexico and northern Central America, and serologic evidence was detected in the Bahamas, Puerto Rico and Cuba. In 2004, the first serologic evidence of WNV activity in South American ecosystems surfaced in September-October in Colombia and Trinidad, where domestic animals circulated WNV-neutralizing antibodies. The sparse reports of equine, human and avian disease in Latin America and the Caribbean is puzzling. Isolates are needed to evaluate viral attenuation or other possible explanations for reduced disease burden in tropical ecosystems.

  15. Kupffer cell structure in the juvenile Nile crocodile, Crocodylus niloticus.

    PubMed

    van Wilpe, Erna; Groenewald, Hermanus Bernardus

    2014-01-01

    The morphology of Kupffer cells was examined in the liver of the juvenile Nile crocodile using light microscopy and transmission electron microscopy. Pleomorphic Kupffer cells were located in the sinusoids, in the space of Disse, in the hepatic parenchyma and often connected adjacent sinusoids. The cell surfaces were irregular due to the presence of filopodia and lamelliapodia with phagocytosis of white blood cells, red blood cells and thrombocytes being evident. The cells were in close contact with endothelial cells and pit cells in the sinusoidal lumen and with stellate cells in the space of Disse. The cytoplasm contained large phagosomes comprising a combination of ceroid pigment, melanosomes and siderosomes. The nuclei were often indented and eccentrically placed due to the presence of the phagosomes. Conspicuous clusters of membrane-bound tubular organelles with a filamentous or crystalline interior were observed in the cytoplasm. The clusters were sometimes separated into smaller groups around phagosomes. A clear zone existed between the limiting membrane and the interior of these tubular organelles with the electron-dense interior profiles being, respectively, circular, angular or divided. The tubular organelles have not previously been described in Kupffer cells and possibly represent lysosomes with specialized functions. Mitochondria, microtubules, Golgi profiles, granular and smooth endoplasmic reticulum, and a few cytoplasmic lipid droplets were also present. The presence of the tubular organelles and the occurrence of the Kupffer cells in different locations in the liver of the juvenile Nile crocodile are indicative of particularly active and mobile cells. Copyright © 2013 Wiley Periodicals, Inc.

  16. Hyperimmune gammaglobulin for the treatment of West Nile virus encephalitis.

    PubMed

    Makhoul, Badira; Braun, Eyal; Herskovitz, Moshe; Ramadan, Rawi; Hadad, Salim; Norberto, Krivoy

    2009-03-01

    West Nile virus, the etiologic agent of West Nile fever, is an emerging mosquito-borne disease. WNV was recognized as a cause of severe human meningoencephalitis in elderly patients during outbreaks in various parts of the world. To analyze WNV encephalitis therapy and its outcome after prescribing hyperimmune gammaglobulin therapy. Eight subjects with WNV encephalitis were treated with supportive therapy and 5 days of IVIG 0.4 g/kg/day containing high WNV antibodies obtained from healthy blood donors. Patients who were treated with IVIG as soon as possible exhibited an improvement in their symptoms. All subjects presented with high fever, progressive confusion and headaches, nausea and vomiting. The Glasgow Coma Screen for six patients ranged between 8 and 13 and all were discharged with a score of 15. The remaining two subjects died during their hospitalization. In severe WNV infection, where the disease affects the central and/or peripheral nervous system, early intervention with IVIG together with supportive treatment is recommended.

  17. Dawn Blue Glow Artist Concept

    NASA Image and Video Library

    2015-03-02

    This artist concept shows NASA Dawn spacecraft arriving at the dwarf planet Ceres. Dawn travels through space using a technology called ion propulsion, with ions glowing with blue light are accelerated out of an engine, giving the spacecraft thrust.

  18. Hazards of solar blue light

    SciTech Connect

    Okuno, Tsutomu

    2008-06-01

    Short-wavelength visible light (blue light) of the Sun has caused retinal damage in people who have stared fixedly at the Sun without adequate protection. The author quantified the blue-light hazard of the Sun according to the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines by measuring the spectral radiance of the Sun. The results showed that the exposure limit for blue light can be easily exceeded when people view the Sun and that the solar blue-light hazard generally increases with solar elevation, which is in accordance with a model of the atmospheric extinction of sunlight. Viewing the Sun can be very hazardous and therefore should be avoided except at very low solar elevations.

  19. Pesticide residues in Nile tilapia (Oreochromis niloticus) and Nile perch (Lates niloticus) from Southern Lake Victoria, Tanzania.

    PubMed

    Henry, L; Kishimba, M A

    2006-03-01

    Nile tilapia (Oreochromis niloticus) and Nile perch (Lates niloticus) samples were collected from fish landing stations in nine riparian districts on the Tanzanian side of Lake Victoria and screened for residues of 64 organochlorine, organophosphorus, carbamate, and pyrethroid pesticides. The residue levels in the fish fillet were up to 0.003, 0.03 and 0.2 mg/kg fresh weight (0.7, 3.8 and 42 mg/kg lipid weight) of fenitrothion, DDT and endosulfan, respectively. Mean levels within sites were up to 0.002, 0.02 and 0.1 mg/kg fresh weight (0.5, 0.5 and 16 mg/kg lipid weight), respectively. The detection of higher levels of p,p'-DDT than the degradation products (p,p'-DDD and p,p'-DDE), and higher levels of endosulfan isomers (alpha and beta) than the sulphate, in fish samples, implied recent exposure of fish to DDT and endosulfan, respectively. Generally, most of the fish samples had residue levels above the average method detection limits (MDLs), but were within the calculated ADI.

  20. Fluorescence resonance energy transfer between DPH and Nile Red in a lipid bilayer

    NASA Astrophysics Data System (ADS)

    Jain, B.; Das, K.

    2006-12-01

    FRET between the well-known membrane binding probes DPH (donor) and Nile Red (acceptor) is investigated in a phosphatidylserine lipid bilayer. A ˜80% FRET efficiency was observed from the steady state experiments for a DPH:Nile Red:lipid molar ratio of 1:2:190, suggesting an efficient FRET process. Time resolved experiments however, provided a lower (˜50%) FRET efficiency. The emission of Nile Red was observed to rise with a time constant of 0.8-0.4 ns only when DPH is selectively excited. This time constant is ascribed due to FRET from which an average donor-acceptor distance of 27 Å is obtained for a DPH:Nile RED:lipid molar ratio of 1:1:190.

  1. 15. VIEW OF THE ORIGINAL 10TON OVERHEAD NILES TRAVELING CRANE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. VIEW OF THE ORIGINAL 10-TON OVERHEAD NILES TRAVELING CRANE. - Washington Water Power Company Post Falls Power Plant, Middle Channel Powerhouse & Dam, West of intersection of Spokane & Fourth Streets, Post Falls, Kootenai County, ID

  2. Egypt, Nile Valley, Gulf of Suez, Sinai as seen from Gemini 12 spacecraft

    NASA Image and Video Library

    1966-11-13

    S66-63477 (13 Nov. 1966) --- United Arab Republic (Egypt), the Nile Valley from Luxor to Cairo, El Payium, Gulf of Suez, Sinai as seen from Gemini-12 spacecraft on its 25th revolution of Earth. Photo credit: NASA

  3. Normal haematology and blood biochemistry of wild Nile crocodiles (Crocodylus niloticus) in the Okavango Delta, Botswana.

    PubMed

    Lovely, C J; Pittman, J M; Leslie, A J

    2007-09-01

    Wild Nile crocodiles (Crocodylus niloticus) of various size classes were captured in the Okavango Delta, Botswana. Blood was collected from the post occipital sinus and used for the determination of a wide range of haematological and biochemical parameters. These values were compared between the sexes and between 3 size classes. The values were also compared with the limited data available from farmed Nile crocodiles, as well as from other wild Nile crocodiles. The Okavango crocodiles were comparatively anaemic, and had comparatively low total protein and blood glucose levels. There was a high prevalence of Hepatozoon pettiti infection, however, there was no significant difference in haematological values between the infected and uninfected crocodiles. The values reported here will be useful in diagnostic investigations in both zoo and farmed Nile crocodiles.

  4. [Vaccination against two vector-borne diseases: bluetongue and West Nile].

    PubMed

    Zientara, Stéphan; Vitour, Damien; Lecollinet, Sylvie

    2012-03-01

    In 1999 and 2006, two viral diseases emerged massively and unexpectedly in the United States (West Nile disease) and northern Europe (bluetongue disease). Control of infectious diseases transmitted by insect vectors is based on a variety of approaches (including sanitary measures), but primarily on vaccination. Vaccination is more efficient and less expensive than monitoring of insect vectors. The dynamics and epidemiology of two arboviral diseases (West Nile and bluetongue) are described, together with the different vaccines and vaccination methods.

  5. Human case of West Nile neuroinvasive disease in Portugal, summer 2015.

    PubMed

    Zé-Zé, Líbia; Proença, Paula; Osório, Hugo C; Gomes, Salomé; Luz, Teresa; Parreira, Paulo; Fevereiro, Miguel; Alves, Maria João

    2015-01-01

    A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human cases (in 2004 and in 2010). Here we present the clinical and laboratory aspects related to the first human case of West Nile neuroinvasive disease reported in Portugal.

  6. DNA Vaccine for West Nile Virus Infection in Fish Crows (Corvus ossifragus)

    DTIC Science & Technology

    2003-09-01

    SUBJECT TERMS west Nile virus, vaccine, efficacy , crows 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 5 19a...crows, Emerging Infectious Diseases • Vol. 9, No. 9, September 2003 1079 RESEARCH Table 1. Effect of route of administration of a DNA West Nile virus...zoologic parks indicate the need to develop an effective avian vaccine for WNV. To break the transmis- sion cycle, the vaccine must be able to

  7. Production of oocytes of Nile tilapia (Oreochromis niloticus) for in vitro fertilization via hormonal treatments.

    PubMed

    Fernandes, A F A; Alvarenga, É R; Oliveira, D A A; Aleixo, C G; Prado, S A; Luz, R K; Sarmento, N L A F; Teixeira, E A; Luz, M R; Turra, E M

    2013-12-01

    Only a few studies have described hormonal treatments for induction of synchronicity and gamete collection in Nile tilapia (Oreochromis niloticus), both important for assortative matings in breeding programmes and essential for polyploidy technologies. In this study, we compared the effectiveness of carp pituitary extract (CPE), Nile tilapia pituitary extract (TPE), human chorionic gonadotropin (hCG) and gonadotropin-releasing hormone (GnRH) protocols on the induction of spawning and egg production in Nile tilapia. Among the hormonal treatments analysed, only hCG was effective for producing viable gametes for in vitro fertilization. To verify the viability of this hormonal treatment, hCG was tested using different doses (1000, 2000, 3000, 4000 and 5000 IU/kg) in a large number of females (208 animals) from two Nile tilapia lines. The results indicated that hCG doses between 1000 and 5000 IU/kg could be used to induce final oocyte maturation in Nile tilapia with collection of stripped oocytes. This is the first study to report differential reproductive responses to hormonal treatment between tilapia lines: line 1 was more efficient at producing eggs and post-hatching larvae after hCG induction than line 2. In conclusion, we demonstrated that the hCG protocol may be applied on a large scale to induce final oocyte maturation in Nile tilapia. The development of a protocol for in vitro fertilization in Nile tilapia may aid in breeding programmes and biotechnological assays for the development of genetically modified lines of Nile tilapia. © 2013 Blackwell Verlag GmbH.

  8. [Acute blue urticaria following subcutaneous injection of patent blue dye].

    PubMed

    Hamelin, A; Vial-Dupuy, A; Lebrun-Vignes, B; Francès, C; Soria, A; Barete, S

    2015-11-01

    Patent blue (PB) is a lymphatic vessel dye commonly used in France for sentinel lymph node detection in breast cancer, and less frequently in melanoma, and which may induce hypersensitivity reactions. We report a case of acute blue urticaria occurring within minutes of PB injection. Ten minutes after PB injection for sentinel lymph node detection during breast cancer surgery, a 49-year-old woman developed generalised acute blue urticaria and eyelid angioedema without bronchospasm or haemodynamic disturbance, but requiring discontinuation of surgery. Skin testing using PB and the anaesthetics given were run 6 weeks after the episode and confirmed PB allergy. PB was formally contra-indicated. Immediate hypersensitivity reactions to PB have been reported for between 0.24 and 2.2% of procedures. Such reactions are on occasion severe, chiefly involving anaphylactic shock. Two mechanisms are probably associated: non-specific histamine release and/or an IgE-mediated mechanism. Skin tests are helpful in confirming the diagnosis of PB allergy. Blue acute urticaria is one of the clinical manifestations of immediate hypersensitivity reactions to patent blue dye. Skin tests must be performed 6 weeks after the reaction in order to confirm the diagnosis and formally contra-indicate this substance. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  9. Clinical and pathologic features of West Nile virus infection in native North American owls (Family strigidae).

    PubMed

    Fitzgerald, S D; Patterson, J S; Kiupel, M; Simmons, H A; Grimes, S D; Sarver, C F; Fulton, R M; Steficek, B A; Cooley, T M; Massey, J P; Sikarskie, J G

    2003-01-01

    Since the initial report of West Nile virus in the northeastern United States in 1999, the virus has spread rapidly westward and southward across the country. In the summer of 2002, several midwestern states reported increased cases of neurologic disease and mortality associated with West Nile virus infection in various native North American owl species. This report summarizes the clinical and pathologic findings for 13 captive and free-ranging owls. Affected species were all in the family Strigidae and included seven snowy owls (Nyctea scandiaca), four great-horned owls (Bubo virginianus), a barred owl (Strix varia), and a short-eared owl (Asio flammeus). Neurologic signs identified included head tilt, uncoordinated flight, paralysis, tremors, and seizures. Owls that died were screened for flaviviral proteins by immunohistochemical staining of formalin-fixed tissues, followed by specific polymerase chain reaction assay to confirm West Nile virus with fresh tissues when available. Microscopic lesions were widespread, involving brain, heart, liver, kidney, and spleen, and were typically nonsuppurative with infiltration by predominantly lymphocytes and plasma cells. Lesions in owls were much more severe than those previously reported in corvids such as crows, which are considered highly susceptible to infection and are routinely used as sentinel species for monitoring for the presence and spread of West Nile virus. This report is the first detailed description of the pathology of West Nile virus infection in Strigiformes and indicates that this bird family is susceptible to natural infection with West Nile virus.

  10. Nile red detection of bacterial hydrocarbons and ketones in a high-throughput format.

    PubMed

    Pinzon, Neissa M; Aukema, Kelly G; Gralnick, Jeffrey A; Wackett, Lawrence P

    2011-01-01

    A method for use in high-throughput screening of bacteria for the production of long-chain hydrocarbons and ketones by monitoring fluorescent light emission in the presence of Nile red is described. Nile red has previously been used to screen for polyhydroxybutyrate (PHB) and fatty acid esters, but this is the first report of screening for recombinant bacteria making hydrocarbons or ketones. The microtiter plate assay was evaluated using wild-type and recombinant strains of Shewanella oneidensis and Escherichia coli expressing the enzyme OleA, previously shown to initiate hydrocarbon biosynthesis. The strains expressing exogenous Stenotrophomonas maltophilia oleA, with increased levels of ketone production as determined by gas chromatography-mass spectrometry, were distinguished with Nile red fluorescence. Confocal microscopy images of S. oneidensis oleA-expressing strains stained with Nile red were consistent with a membrane localization of the ketones. This differed from Nile red staining of bacterial PHB or algal lipid droplets that showed intracellular inclusion bodies. These results demonstrated the applicability of Nile red in a high-throughput technique for the detection of bacterial hydrocarbons and ketones. © 2011 Pinzon et al.

  11. "Clothed in triple blues": sorting out the Italian blues.

    PubMed

    Bimler, David; Uusküla, Mari

    2014-04-01

    Cross-cultural comparisons of color perception and cognition often feature versions of the "similarity sorting" procedure. By interpreting the assignment of two color samples to different groups as an indication that the dissimilarity between them exceeds some threshold, sorting data can be regarded as low-resolution similarity judgments. Here we analyze sorting data from speakers of Italian, Russian, and English, applying multidimensional scaling to delineate the boundaries between perceptual categories while highlighting differences between the three populations. Stimuli were 55 color swatches, predominantly from the blue region. Results suggest that at least two Italian words for "blue" are basic, a similar situation to Russian, in contrast to English where a single "blue" term is basic.

  12. Use of Testing for West Nile Virus and Other Arboviruses

    PubMed Central

    Vanichanan, Jakapat; Salazar, Lucrecia; Wootton, Susan H.; Aguilera, Elizabeth; Garcia, Melissa N.; Murray, Kristy O.

    2016-01-01

    In the United States, the most commonly diagnosed arboviral disease is West Nile virus (WNV) infection. Diagnosis is made by detecting WNV IgG or viral genomic sequences in serum or cerebrospinal fluid. To determine frequency of this testing in WNV-endemic areas, we examined the proportion of tests ordered for patients with meningitis and encephalitis at 9 hospitals in Houston, Texas, USA. We identified 751 patients (567 adults, 184 children), among whom 390 (52%) experienced illness onset during WNV season (June–October). WNV testing was ordered for 281 (37%) of the 751; results indicated acute infection for 32 (11%). Characteristics associated with WNV testing were acute focal neurologic deficits; older age; magnetic resonance imaging; empirically prescribed antiviral therapy; worse clinical outcomes: and concomitant testing for mycobacterial, fungal, or other viral infections. Testing for WNV is underutilized, and testing of patients with more severe disease raises the possibility of diagnostic bias in epidemiologic studies. PMID:27537988

  13. Identification and quantification of microplastics using Nile Red staining.

    PubMed

    Shim, Won Joon; Song, Young Kyoung; Hong, Sang Hee; Jang, Mi

    2016-12-15

    We investigated the applicability of Nile Red (NR), a fluorescent dye, for microplastic analysis, and determined the optimal staining conditions. Five mg/L NR solution in n-hexane effectively stained plastics, and they were easily recognized in green fluorescence. The NR staining method was successfully applied to micro-sized polyethylene, polypropylene, polystyrene, polycarbonate, polyurethane, and poly(ethylene-vinyl acetate), except for polyvinylchloride, polyamide and polyester. The recovery rate of polyethylene (100-300μm) spiked to pretreated natural sand was 98% in the NR stating method, which was not significantly (p<0.05) different with FT-IR identification. The NR staining method was suitable for discriminating fragmented polypropylene particles from large numbers of sand particles in laboratory weathering test samples. The method is straightforward and quick for identifying and quantifying polymer particles in the laboratory controlled samples. Further studies, however, are necessary to investigate the application of NR staining to field samples with organic remnants.

  14. Characterization of Virulent West Nile Virus Kunjin Strain, Australia, 2011

    PubMed Central

    Frost, Melinda J.; Zhang, Jing; Edmonds, Judith H.; Prow, Natalie A.; Gu, Xingnian; Davis, Rodney; Hornitzky, Christine; Arzey, Kathleen E.; Finlaison, Deborah; Hick, Paul; Read, Andrew; Hobson-Peters, Jody; May, Fiona J.; Doggett, Stephen L.; Haniotis, John; Russell, Richard C.; Hall, Roy A.; Khromykh, Alexander A.

    2012-01-01

    To determine the cause of an unprecedented outbreak of encephalitis among horses in New South Wales, Australia, in 2011, we performed genomic sequencing of viruses isolated from affected horses and mosquitoes. Results showed that most of the cases were caused by a variant West Nile virus (WNV) strain, WNVNSW2011, that is most closely related to WNV Kunjin (WNVKUN), the indigenous WNV strain in Australia. Studies in mouse models for WNV pathogenesis showed that WNVNSW2011 is substantially more neuroinvasive than the prototype WNVKUN strain. In WNVNSW2011, this apparent increase in virulence over that of the prototype strain correlated with at least 2 known markers of WNV virulence that are not found in WNVKUN. Additional studies are needed to determine the relationship of the WNVNSW2011 strain to currently and previously circulating WNVKUN strains and to confirm the cause of the increased virulence of this emerging WNV strain. PMID:22516173

  15. Clinical characteristics of the West Nile fever outbreak, Israel, 2000.

    PubMed Central

    Chowers, M. Y.; Lang, R.; Nassar, F.; Ben-David, D.; Giladi, M.; Rubinshtein, E.; Itzhaki, A.; Mishal, J.; Siegman-Igra, Y.; Kitzes, R.; Pick, N.; Landau, Z.; Wolf, D.; Bin, H.; Mendelson, E.; Pitlik, S. D.; Weinberger, M.

    2001-01-01

    West Nile (WN) virus is endemic in Israel. The last reported outbreak had occurred in 1981. From August to October 2000, a large-scale epidemic of WN fever occurred in Israel; 417 cases were confirmed, with 326 hospitalizations. The main clinical presentations were encephalitis (57.9%), febrile disease (24.4%), and meningitis (15.9%). Within the study group, 33 (14.1%) hospitalized patients died. Mortality was higher among patients >70 years (29.3%). On multivariate regressional analysis, independent predictors of death were age >70 years (odds ratio [OR] 7.7), change in level of consciousness (OR 9.0), and anemia (OR 2.7). In contrast to prior reports, WN fever appears to be a severe illness with high rate of central nervous system involvement and a particularly grim outcome in the elderly. PMID:11585531

  16. Experimental infections of wild birds with West Nile virus.

    PubMed

    Pérez-Ramírez, Elisa; Llorente, Francisco; Jiménez-Clavero, Miguel Ángel

    2014-02-13

    Avian models of West Nile virus (WNV) disease have become pivotal in the study of infection pathogenesis and transmission, despite the intrinsic constraints that represents this type of experimental research that needs to be conducted in biosecurity level 3 (BSL3) facilities. This review summarizes the main achievements of WNV experimental research carried out in wild birds, highlighting advantages and limitations of this model. Viral and host factors that determine the infection outcome are analyzed in detail, as well as recent discoveries about avian immunity, viral transmission, and persistence achieved through experimental research. Studies of laboratory infections in the natural host will help to understand variations in susceptibility and reservoir competence among bird species, as well as in the epidemiological patterns found in different affected areas.

  17. Avian hosts of West Nile virus in Puerto Rico.

    PubMed

    Komar, Nicholas; Bessoff, Kovi; Diaz, Annette; Amador, Manuel; Young, Ginger; Seda, Rafael; Perez, Taonex; Hunsperger, Elizabeth

    2012-01-01

    West Nile virus (WNV) ecology in neotropical ecosystems is poorly understood, and vertebrate hosts responsible for infecting mosquitoes remain unidentified throughout the Caribbean Basin. After a period of intense WNV transmission among sentinel chickens near Ceiba, Puerto Rico, we measured abundance of resident birds and species-specific prevalence of WNV infection. Taking the product of these measures indicates the relative number of WNV infections by species. Greater Antillean grackle (Quiscalus niger) accounted for the most WNV infections among birds in our 100-km(2) study site. In urban habitats, the house sparrow (Passer domesticus) was frequently infected. Immature birds less than one year of age were more likely to have detectable WNV-reactive antibodies than older birds of the same species.

  18. Globalization, land use and the invasion of West Nile virus

    PubMed Central

    Kilpatrick, A. Marm

    2012-01-01

    Many invasive species that have been spread through the globalization of trade and travel are infectious pathogens. A paradigmatic case is the introduction of West Nile virus (WNV) into North America in 1999. A decade of research on the ecology and evolution of WNV includes three findings that provide insight into the outcome of future viral introductions. First, WNV transmission in North America is highest in urbanized and agricultural habitats, in part because the hosts and vectors of WNV are abundant in human-modified areas. Second, after its introduction, the virus quickly adapted to infect local mosquito vectors more efficiently than the originally introduced strain. Third, highly focused feeding patterns of the mosquito vectors of WNV result in unexpected host species being important for transmission. These findings provide a framework for predicting and preventing the emergence of foreign vector-borne pathogens. PMID:22021850

  19. West Nile virus infections in Greece: an update.

    PubMed

    Papa, Anna

    2012-07-01

    Approximately 2 years have passed since the detection of the first human case of West Nile virus (WNV) infection in Greece, which was the starting signal of a large outbreak in 2010, followed by a second one in 2011. More than 250 neuroinvasive disease cases with 15% fatality were observed during the two WNV seasons. WNV lineage 2 sequences were obtained from blood donors, Culex mosquitoes, wild birds and sentinel chickens. The Greek WNV strain shows high genetic relatedness to the goshawk-Hungary/04 WNV strain; an amino acid substitution in nonstructural protein 3 (H249P) is observed, which has been previously associated with increased virus transmission. This article provides an overview of the WNV outbreaks in Greece and discusses the knowledge gained from these events.

  20. West Nile virus range expansion into British Columbia.

    PubMed

    Roth, David; Henry, Bonnie; Mak, Sunny; Fraser, Mieke; Taylor, Marsha; Li, Min; Cooper, Ken; Furnell, Allen; Wong, Quantine; Morshed, Muhammad

    2010-08-01

    In 2009, an expansion of West Nile virus (WNV) into the Canadian province of British Columbia was detected. Two locally acquired cases of infection in humans and 3 cases of infection in horses were detected by ELISA and plaque-reduction neutralization tests. Ten positive mosquito pools were detected by reverse transcription PCR. Most WNV activity in British Columbia in 2009 occurred in the hot and dry southern Okanagan Valley. Virus establishment and amplification in this region was likely facilitated by above average nightly temperatures and a rapid accumulation of degree-days in late summer. Estimated exposure dates for humans and initial detection of WNV-positive mosquitoes occurred concurrently with a late summer increase in Culex tarsalis mosquitoes (which spread western equine encephalitis) in the southern Okanagan Valley. The conditions present during this range expansion suggest that temperature and Cx. tarsalis mosquito abundance may be limiting factors for WNV transmission in this portion of the Pacific Northwest.

  1. West Nile virus infection in horses, Indian ocean.

    PubMed

    Cardinale, E; Bernard, C; Lecollinet, S; Rakotoharinome, V M; Ravaomanana, J; Roger, M; Olive, M M; Meenowa, D; Jaumally, M R; Melanie, J; Héraud, J M; Zientara, S; Cêtre-Sossah, C

    2017-08-01

    The circulation of West Nile virus (WNV) in horses was investigated in the Southwest Indian ocean. In 2010, blood samples were collected from a total of 303 horses originating from Madagascar, Mauritius, Reunion and the Seychelles and tested for WNV-specific antibodies. An overall seroprevalence of 27.39% was detected in the Indian Ocean with the highest WNV antibody prevalence of 46.22% (95% CI: [37.4-55.2%]) in Madagascar. The age and origin of the horses were found to be associated with the WNV infection risk. This paper presents the first seroprevalence study investigating WN fever in horses in the Southwest Indian Ocean area and indicates a potential risk of infection for humans and animals. In order to gain a better understanding of WN transmission cycles, WNV surveillance needs to be implemented in each of the countries. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Ixodid and Argasid Tick Species and West Nile Virus

    PubMed Central

    Uzcátegui, Nathalie Yumari; Gould, Ernest Andrew; Nuttall, Patricia Anne

    2004-01-01

    Control of West Nile virus (WNV) can only be effective if the vectors and reservoirs of the virus are identified and controlled. Although mosquitoes are the primary vectors, WNV has repeatedly been isolated from ticks. Therefore tick-borne transmission studies were performed with an ixodid (Ixodes ricinus) and an argasid tick species (Ornithodoros moubata). Both species became infected after feeding upon viremic hosts, but I. ricinus ticks were unable to maintain the virus. In contrast, O. moubata ticks were infected for at least 132 days, and the infection was maintained through molting and a second bloodmeal. Infected O. moubata ticks transmitted the virus to rodent hosts, albeit at a low level. Moreover, the virus was nonsystemically transmitted between infected and uninfected O. moubata ticks co-fed upon uninfected hosts. Although ticks are unlikely to play a major role in WNV transmission, our findings suggest that some species have the potential to act as reservoirs for the virus. PMID:15200855

  3. The Global Ecology and Epidemiology of West Nile Virus

    PubMed Central

    Rios, Maria

    2015-01-01

    Since its initial isolation in Uganda in 1937 through the present, West Nile virus (WNV) has become an important cause of human and animal disease worldwide. WNV, an enveloped virus of the genus Flavivirus, is naturally maintained in an enzootic cycle between birds and mosquitoes, with occasional epizootic spillover causing disease in humans and horses. The mosquito vectors for WNV are widely distributed worldwide, and the known geographic range of WNV transmission and disease has continued to increase over the past 77 years. While most human infections with WNV are asymptomatic, severe neurological disease may develop resulting in long-term sequelae or death. Surveillance and preventive measures are an ongoing need to reduce the public health impact of WNV in areas with the potential for transmission. PMID:25866777

  4. Experimental Infections of Wild Birds with West Nile Virus

    PubMed Central

    Pérez-Ramírez, Elisa; Llorente, Francisco; Jiménez-Clavero, Miguel Ángel

    2014-01-01

    Avian models of West Nile virus (WNV) disease have become pivotal in the study of infection pathogenesis and transmission, despite the intrinsic constraints that represents this type of experimental research that needs to be conducted in biosecurity level 3 (BSL3) facilities. This review summarizes the main achievements of WNV experimental research carried out in wild birds, highlighting advantages and limitations of this model. Viral and host factors that determine the infection outcome are analyzed in detail, as well as recent discoveries about avian immunity, viral transmission, and persistence achieved through experimental research. Studies of laboratory infections in the natural host will help to understand variations in susceptibility and reservoir competence among bird species, as well as in the epidemiological patterns found in different affected areas. PMID:24531334

  5. Differential Virulence of West Nile Strains for American Crows

    PubMed Central

    Langevin, Stanley A.; Bowen, Richard A.; Panella, Nicholas A.; Biggerstaff, Brad J.; Miller, Barry R.; Komar, Nicholas

    2004-01-01

    Crow deaths were observed after West Nile virus (WNV) was introduced into North America, and this phenomenon has subsequently been used to monitor the spread of the virus. To investigate potential differences in the crow virulence of different WNV strains, American Crows were inoculated with Old World strains of WNV from Kenya and Australia (Kunjin) and a North American (NY99) WNV genotype. Infection of crows with NY99 genotype resulted in high serum viremia levels and death; the Kenyan and Kunjin genotypes elicited low viremia levels and minimal deaths but resulted in the generation of neutralizing antibodies capable of providing 100% protection from infection with the NY99 strain. These results suggest that genetic alterations in NY99 WNV are responsible for the crow-virulent phenotype and that increased replication of this strain in crows could spread WNV in North America. PMID:15663854

  6. Dead Crow Density and West Nile Virus Monitoring, New York

    PubMed Central

    Schmit, Kate; Hagiwara, Yoichiro; Anand, Madhu; Backenson, P. Bryon; Gotham, Ivan; Kramer, Laura

    2005-01-01

    New York State used the health commerce system to monitor the number of West Nile virus (WNV) human disease cases and the density of dead crows. In each year from 2001 to 2003 and for the 3 years combined, persons living in New York counties (excluding New York City) with elevated weekly dead crow densities (above a threshold value of 0.1 dead crows per square mile) had higher risk (2.0–8.6 times) for disease caused by WNV within the next 2 weeks than residents of counties reporting fewer dead crows per square mile. This type of index can offer a real-time, relatively inexpensive window into viral activity in time for prevention and control. Changes in reporting, bird populations, and immunity may require that thresholds other than 0.1 be used in later years or in other areas. PMID:16229764

  7. Overview of West Nile Virus Transmission and Epidemiology.

    PubMed

    Troupin, Andrea; Colpitts, Tonya M

    2016-01-01

    West Nile virus (WNV) is a mosquito-borne flavivirus that can cause mild-to-severe disease in humans and horses. WNV was first documented in Uganda in 1937 and passed through the majority of Africa, West Asia, and Europe before arriving in the USA (with infections in New York City in 1999). After the spread of the virus on the US east coast, it traveled westward, northward, and southward through the USA and into Central and South America. WNV can cause fever, rashes, nausea, vomiting, and potentially neuroinvasive disease or death. The virus is sustained through a mosquito-bird-mosquito cycle and there are many species that are competent vectors. Unfortunately, there are no vaccines and the only treatment is supportive care. This chapter highlights the epidemiology and transmission of WNV and provides insight into some of the challenges of controlling WNV disease.

  8. A Mouse Model of Chronic West Nile Virus Disease

    PubMed Central

    Graham, Jessica B.; Swarts, Jessica L.; Wilkins, Courtney; Thomas, Sunil; Green, Richard; Sekine, Aimee; Voss, Kathleen M.; Mooney, Michael; Choonoo, Gabrielle; Miller, Darla R.; Pardo Manuel de Villena, Fernando; Gale, Michael

    2016-01-01

    Infection with West Nile virus (WNV) leads to a range of disease outcomes, including chronic infection, though lack of a robust mouse model of chronic WNV infection has precluded identification of the immune events contributing to persistent infection. Using the Collaborative Cross, a population of recombinant inbred mouse strains with high levels of standing genetic variation, we have identified a mouse model of persistent WNV disease, with persistence of viral loads within the brain. Compared to lines exhibiting no disease or marked disease, the F1 cross CC(032x013)F1 displays a strong immunoregulatory signature upon infection that correlates with restraint of the WNV-directed cytolytic response. We hypothesize that this regulatory T cell response sufficiently restrains the immune response such that a chronic infection can be maintained in the CNS. Use of this new mouse model of chronic neuroinvasive virus will be critical in developing improved strategies to prevent prolonged disease in humans. PMID:27806117

  9. Vector Competence of California Mosquitoes for West Nile virus

    PubMed Central

    Roth, Amy E.; Reisen, William K.; Scott, Thomas W.

    2002-01-01

    To identify the mosquito species competent for West Nile virus (WNV) transmission, we evaluated 10 California species that are known vectors of other arboviruses or major pests: Culex tarsalis, Cx. pipiens pipiens, Cx. p. quinquefasciatus, Cx. stigmatosoma, Cx. erythrothorax, Ochlerotatus dorsalis, Oc. melanimon, Oc. sierrensis, Aedes vexans, and Culiseta inornata. All 10 became infected and were able to transmit WNV at some level. Ochlerotatus, Culiseta, and Aedes were low to moderately efficient vectors. They feed primarily on mammals and could play a secondary role in transmission. Oc. sierrensis, a major pest species, and Cx. p. quinquefasciatus from southern California were the least efficient laboratory vectors. Cx. tarsalis, Cx. stigmatosoma, Cx. erythrothorax, and other populations of Cx. pipiens complex were the most efficient laboratory vectors. Culex species are likely to play the primary role in the enzootic maintenance and transmission of WNV in California. PMID:12498652

  10. The relationships between West Nile and Kunjin viruses.

    PubMed Central

    Scherret, J. H.; Poidinger, M.; Mackenzie, J. S.; Broom, A. K.; Deubel, V.; Lipkin, W. I.; Briese, T.; Gould, E. A.; Hall, R. A.

    2001-01-01

    Until recently, West Nile (WN) and Kunjin (KUN) viruses were classified as distinct types in the Flavivirus genus. However, genetic and antigenic studies on isolates of these two viruses indicate that the relationship between them is more complex. To better define this relationship, we performed sequence analyses on 32 isolates of KUN virus and 28 isolates of WN virus from different geographic areas, including a WN isolate from the recent outbreak in New York. Sequence comparisons showed that the KUN virus isolates from Australia were tightly grouped but that the WN virus isolates exhibited substantial divergence and could be differentiated into four distinct groups. KUN virus isolates from Australia were antigenically homologous and distinct from the WN isolates and a Malaysian KUN virus. Our results suggest that KUN and WN viruses comprise a group of closely related viruses that can be differentiated into subgroups on the basis of genetic and antigenic analyses. PMID:11585535

  11. West Nile virus epizootiology in the southeastern United States, 2001.

    PubMed

    Godsey, Marvin S; Blackmore, Mark S; Panella, Nicholas A; Burkhalter, Kristen; Gottfried, Kristy; Halsey, Lawrence A; Rutledge, Roxanne; Langevin, Stanley A; Gates, Robert; Lamonte, Karen M; Lambert, Amy; Lanciotti, Robert S; Blackmore, Carina G M; Loyless, Tom; Stark, Lillian; Oliveri, Robin; Conti, Lisa; Komar, Nicholas

    2005-01-01

    We investigated mosquito and bird involvement in West Nile virus (WNV) transmission in July 2001 in Jefferson County, FL, and Lowndes County, GA. We detected 16 WNV-infected pools from Culex quinquefasciatus, Cx. salinarius, Cx. nigripalpus, and Culiseta melanura. In Florida, 11% of 353 bird sera neutralized WNV. Antibody prevalence was greatest in northern cardinal (Cardinalis cardinalis, 75%), northern mockingbird (Mimus polyglottus, 50%), common ground-dove (Columbina passerina, 25%), common grackle (Quiscalus quiscula, 15%), domestic chicken (Gallus gallus, 16%), and house sparrow (Passer domesticus, 11%). Antibody-positive birds were detected in nine of 11 locations, among which prevalence in chickens ranged from 0% to 100%. Seropositive chickens were detected in Georgia as well. The primary transmission cycle of WNV in the southeastern United States apparently involves Culex mosquitoes and passerine birds. Chickens are frequently infected and may serve as effective sentinels in this region.

  12. West Nile virus encephalitis with myositis and orchitis.

    PubMed

    Smith, Roger D; Konoplev, Sergiej; DeCourten-Myers, Gabrielle; Brown, Thomas

    2004-02-01

    This report documents the hospital course and autopsy findings of a 43-year-old man with a renal allograft who died of West Nile virus (WNV) encephalitis. Central nervous system (CNS) findings were those of severe necrotizing and hemorrhagic encephalitis affecting gray matter regions limited to the diencepahlon, rhombencephalon, spinal cord, and limbic system. The bilateral process exhibited preferential involvement of motor neurons. Brain imaging obtained 6 days before death demonstrated an unusual pattern of involvement corresponding with the autopsy findings, confirming that imaging may be a specific diagnostic guide in WNV encephalitis. Extra-CNS findings include myositis with T-lymphocyte infiltration of nerve fibers, suggesting that the virus may reach the CNS via peripheral nerves. Orchitis with dense T-lymphocyte infiltration and syncytial cell formation thought to be due to WNV were also noted.

  13. Peste des petits ruminants outbreaks in White Nile State, Sudan.

    PubMed

    Ishag, Osama M; Saeed, Intisar K; Ali, Yahia H

    2015-08-21

    Eight outbreaks of peste des petits ruminants in sheep and goats were reported in White Nile State, Sudan, between 2008 and 2009. A mortality rate of 4.2% was reported across the different outbreaks. Clinically the disease was characterised by high fever, ocular and nasal discharge, pneumonia, ulceration of the mucous membranes, diarrhoea and death. The postmortem findings included necrotic lesions in the mouth and gastrointestinal tract, and swollen, oedematous lymph nodes associated with the lungs and intestine. Of the 209 serum samples tested by competitive enzyme-linked immunosorbent assay, 113 (54%) were found positive. Peste des petits ruminants virus was confirmed in tissues, nasal swabs and blood samples by immunocapture enzyme-linked immunosorbent assay, reverse-transcription polymerase chain reaction and isolation of the virus in culture of lamb testicle cells.

  14. Fatal West Nile virus encephalitis in a renal transplant recipient.

    PubMed

    Cushing, Melissa M; Brat, Daniel J; Mosunjac, Mario I; Hennigar, Randolph A; Jernigan, Daniel B; Lanciotti, Robert; Petersen, Lyle R; Goldsmith, Cynthia; Rollin, Pierre E; Shieh, Wun-Ju; Guarner, Jeannette; Zaki, Sherif R

    2004-01-01

    West Nile virus (WNV), a mosquito-transmitted single-stranded RNA flavivirus, causes human disease of variable severity. We report clinical and pathologic findings of fatal encephalitis from the transmission of WNV from an organ donor to a kidney transplant recipient. The patient developed a febrile illness 18 days after transplantation, which progressed to encephalitis. Postmortem examination demonstrated extensive viral encephalopathic changes. Immunohistochemical studies highlighted WNV antigens within neurons, especially in the cerebellum and brainstem. Flavivirus virions were detected ultrastructurally within the cerebellum, and WNV was isolated from the brain and the brainstem. Thus, this case demonstrates the first death in the first solid organ transplant-associated transmission of WNV. Immunosuppression of the transplant recipient might have been responsible for the fulminant viral effects. The pathologic diagnosis helped guide subsequent epidemiologic and laboratory studies.

  15. Frequency of West Nile Virus Infection in Iranian Blood Donors.

    PubMed

    Aghaie, Afsaneh; Aaskov, John; Chinikar, Sadegh; Niedrig, Matthias; Banazadeh, Soudabeh; Mohammadpour, Hashem Khorsand

    2016-09-01

    West Nile virus (WNV) can be transmitted by blood transfusions and organ transplants. This study was a retrospective study which was performed in Blood Transfusion Center to evaluate the WNV infection in blood donors in Iran. A total of 540 blood samples were taken from volunteer healthy donors who referred for blood donation to Chabahar Blood Center. The presence of WNV was studied by detecting immunoglobulin G (IgG) WNV by enzyme linked immune sorbent assay (ELISA). Demonstration of elevated WNV IgG confirmed by immunoflouorescence assay (IFA) Euroimmun kit. Out of the 540 samples 17.96 % (97 cases) were seropositive by ELISA and 1.48 % (8 cases) was seropositive by IFA. This means that 8.24 % of ELISA seropositive samples were confirmed by IFA. Special attention should be paid to criteria of donor selection, albeit positive results may be due to a previous infection in these donors.

  16. Molecular alterations in malignant blue nevi and related blue lesions.

    PubMed

    Yilmaz, Ismail; Gamsizkan, Mehmet; Sari, Sule Ozturk; Yaman, Banu; Demirkesen, Cuyan; Heper, Aylin; Calli, Aylin Orgen; Narli, Gizem; Kucukodaci, Zafer; Berber, Ufuk; Demirel, Dilaver; Akalin, Taner; Demiriz, Murat; Buyukbabani, Nesimi

    2015-12-01

    Malignant blue nevi (MBN) are extremely rare dermal melanocytic tumors that arise in association with atypical cellular blue nevi (ACBN), cellular blue nevi (CBN), common blue nevi (BN), or de novo. The frequency of BRAF, NRAS, and KIT mutations in malignant melanoma varies according to histological subtype and localization. These mutations are rarely observed in blue nevi, which have recently been shown to carry activating mutations in GNAQ/GNA11 genes. Only few small molecular studies of MBN have been published. The aim of the present study was to analyze in MBN and related blue lesions such as ACBN, CBN, and BN the prevalence of BRAF, NRAS, KIT, GNAQ, and GNA11 gene mutations and their association with clinicopathological features. We included in our study 12 MBN, 6 ACBN, 29 CBN, and 35 common BN diagnosed between 1996 and 2014. Sanger sequencing method was used for mutation analysis. Overall, GNAQ exon 5 mutation was the most frequent alteration (46 %), in 2 of 12 (17 %) MBN, 1 of 6 (17 %) ACBN, 22 of 29 (76 %) CBN, and 13 of 35 (37 %) common BN. BRAF V600E and GNA11 exon 5 mutations were respectively detected in 3 of 12 (25 %) and in 2 of 12 (17 %) MBN while none in ACBN, CBN, and common BN. None of the cases harbored NRAS exon 2/3, KIT exon 9/11/13/17/18, or GNAQ/GNA11 exon 4 mutations. GNAQ gene exon 5 mutations are rare in MBN and ACBN but frequent in CBN and common BN. Remarkably, BRAF V600E and GNA11 exon 5 mutations were only detected in MBN, whereas none were found in ACBN, CBN, or common BN. Our data contribute new elements to the limited data on molecular alterations in MBN.

  17. Diversification of West Nile virus in a subtropical region.

    PubMed

    Chisenhall, Daniel M; Mores, Christopher N

    2009-07-16

    West Nile virus (WNV) has spread across North, Central, and South America since its introduction in 1999. At the start of this spread, Florida was considered a potentially important area with regards to transmission due to its geographic, climatological, and demographic conditions. Curiously, the anticipated high levels of transmission or disease outbreaks have not been observed. As other studies have predicted that the lack of intense WNV transmission is not due to vector incompetence, we sought to evaluate the role of viral strain diversity in WNV transmission in Florida. Therefore, a phylogentic analysis was carried out on several isolates collected from three distinct locations in Florida. Contrasting with a positive control collected in Indian River County, Florida during 2003 that contains the original NY99 genotype with valanine at amino acid 159 of the envelope region, all of the isolates collected in 2005 contain the WN02 genotype composed of a substation with alanine at that position indicating the window of introduction of the WN02 genotype occurred between 2003 and 2005. From the eight isolates collected in Duval, Indian River, and Manatee Counties; there is also a silent nucleotide substitution that differentiates the isolates collected on the Atlantic side of the state compared to the isolate collected on the Gulf side, which groups closer to isolates from other locations near the Gulf. As a whole, the Florida isolates contained numerous variable nucleotide and amino acid sites from the reference sequences, as well as each other; indicating greater nucleotide diversity within the Florida 2005 isolates than within other regions. Finally, a series of three amino acid substitutions surrounding a set of histidines located in the envelope coding region that hypothesized to play a role in conformational changes was found in the isolate collected in Indian River County, perhaps changing the antigenicity of the homodimer. Taken together, these findings expand

  18. Chemical restraint of the Nile hippopotamus (Hippopotamus amphibius) in captivity.

    PubMed

    Ramsay, E C; Loomis, M R; Mehren, K G; Boardman, W S; Jensen, J; Geiser, D

    1998-03-01

    This retrospective study describes 16 immobilizations performed on nine adult captive Nile hippopotamus (Hippopotamus amphibius). Animals were immobilized using intramuscular etorphine alone (1.0-5.0 micrograms/kg; n = 9) or in combination with xylazine (67-83 micrograms/kg; n = 6) or acepromazine (20 micrograms/kg; n = 1). Exact weights for the animals were unknown so drug dosages were based on estimated weights. Seven animals either were in good health or had minor or localized medical problems. Following etorphine and xylazine induction, one animal undergoing castration was anesthetized with isoflurane in oxygen delivered by endotracheal tube. Ten immobilizations occurred without complications, and eight of those procedures were rated as good or excellent. Complications, including bradypnea, cyanosis, and apnea, occurred during six immobilizations. One animal died following prolonged apnea, and the necropsy failed to find a specific cause of death. Immobilizations were reversed with diprenorphine alone (4.4-10.0 micrograms/kg; n = 13), diprenorphine (2.9 micrograms/kg) and naloxone (14.6 mu k/kg; n = 1), or naltrexone (146-180 micrograms/kg; n = 2). Mean time to reversal of immobilization for those animals given etorphine alone and reversed with diprenorphine alone was 21.6 min (n = 5). Time to reversal for the two immobilizations reversed with only naltrexone was 4 min. No renarcotizations were observed. Total doses of 2.0-6.0 mg etorphine i.m. should produce heavy sedation to surgical anesthesia in calm adult captive Nile hippopotamuses. Insufflation with oxygen during immobilization seems warranted.

  19. Environmental predictors of West Nile fever risk in Europe

    PubMed Central

    2014-01-01

    Background West Nile virus (WNV) is a mosquito-borne pathogen of global public health importance. Transmission of WNV is determined by abiotic and biotic factors. The objective of this study was to examine environmental variables as predictors of WNV risk in Europe and neighboring countries, considering the anomalies of remotely sensed water and vegetation indices and of temperature at the locations of West Nile fever (WNF) outbreaks reported in humans between 2002 and 2013. Methods The status of infection by WNV in relationship to environmental and climatic risk factors was analyzed at the district level using logistic regression models. Temperature, remotely sensed Normalized Difference Vegetation Index (NDVI) and Modified Normalized Difference Water Index (MNDWI) anomalies, as well as population, birds’ migratory routes, and presence of wetlands were considered as explanatory variables. Results The anomalies of temperature in July, of MNDWI in early June, the presence of wetlands, the location under migratory routes, and the occurrence of a WNF outbreak the previous year were identified as risk factors. The best statistical model according to the Akaike Information Criterion was used to map WNF risk areas in 2012 and 2013. Model validations showed a good level of prediction: area under Receiver Operator Characteristic curve = 0.854 (95% Confidence Interval 0.850-0.856) for internal validation and 0.819 (95% Confidence Interval 0.814-0.823) (2012) and 0.853 (95% Confidence Interval 0.850-0.855) (2013) for external validations, respectively. Conclusions WNF incidence is increasing in Europe and WNV is expanding into new areas where it had never been observed before. Our model can be used to direct surveillance activities and public health interventions for the upcoming WNF season. PMID:24986363

  20. Modeling of Groundwater Quantity and Quality Management, Nile Valley, Egypt

    NASA Astrophysics Data System (ADS)

    Owlia, R.; Fogg, G. E.

    2012-12-01

    Groundwater levels have been rising in the Luxor area of Egypt due to increased agricultural irrigation following the construction of the Aswan High Dam (AHD) in 1970. This has led to soil and groundwater salinity problems caused by increasing evapotranspiration from shallower water table, as well as the degradation of historical monuments whose foundations are weakening by capillary rise of water into the columns and stonework. While similar salinity problems exist elsewhere in the world (e.g., San Joaquin Valley of California), we hypothesize that as long as groundwater discharge to the Nile River continues and serves as a sink for the salt, the regional salt balance will be manageable and will not lead to irreversible salinization of soils. Further, we hypothesize that if a groundwater system such as this one becomes overdrafted, thereby cutting off groundwater discharge to the River, the system salt balance will be less manageable and possibly non-sustainable. With groundwater flow modeling we are investigating approaches for managing the irrigation and groundwater levels so as to eliminate water stresses on Egyptian monuments and antiquities. Consequences of possible actions for managing the water table through groundwater pumping and alternative irrigation practices will be presented. Moreover, through the use of high resolution modeling of system heterogeneity, we will simulate the long term salt balance of the system under various scenarios, including the overdraft case. The salt source will be a function of groundwater discharge to the surface via bare-soil evaporation and crop transpiration. The built-in heterogeneity will account for dispersion, fast transport in connected media and slow mass transfer between aquifer and aquitard materials. Key Words: Groundwater, modeling, water quality, sustainability, salinity, irrigated agriculture, Nile aquifer.

  1. Intraperitoneal germ cell transplantation in the Nile tilapia Oreochromis niloticus.

    PubMed

    Farlora, Rodolfo; Hattori-Ihara, Shoko; Takeuchi, Yukata; Hayashi, Makoto; Octavera, Anna; Alimuddin; Yoshizaki, Goro

    2014-06-01

    Germ cell transplantation offers promising applications in finfish aquaculture and the preservation of endangered species. Here, we describe an intraperitoneal spermatogonia transplantation procedure in the Nile tilapia Oreochromis niloticus. Through histological analysis of early gonad development, we first determined the best suitable stage at which exogenous germ cells should be transplanted into the recipients. For the transplantation procedure, donor testes from a transgenic Nile tilapia strain carrying the medaka β-actin/enhanced green fluorescent protein (EGFP) gene were subjected to enzymatic dissociation. These testicular cells were then stained with PKH26 and microinjected into the peritoneal cavity of the recipient fish. To confirm colonization of the donor-derived germ cells, the recipient gonads were examined by fluorescent and confocal microscopy. PKH26-labeled cells exhibiting typical spermatogonial morphology were incorporated into the recipient gonads and were not rejected within 22 days posttransplantation. Long-term survival of transgenic donor-derived germ cells was then verified in the gonads of 5-month-old recipients and in the milt and vitelogenic oocytes of 1-year-old recipients, by means of PCR using EGFP-specific primers. EGFP-positive milt from adult male recipients was used to fertilize non-transgenic oocytes and produced transgenic offspring expressing the donor-derived phenotype. These results imply that long-term survival, proliferation, and differentiation of the donor-derived spermatogonia into vitelogenic oocytes and functional spermatozoa are all possible. Upon further improvements in the transplantation efficiency, this intraperitoneal transplantation system could become a valuable tool in the conservation of genetic resources for cichlid species.

  2. West Nile Virus: Seroprevalence in Animals in Palestine and Israel.

    PubMed

    Azmi, Kifaya; Tirosh-Levy, Sharon; Manasrah, Mu'taz; Mizrahi, Rotem; Nasereddin, Abed; Al-Jawabreh, Amer; Ereqat, Suheir; Abdeen, Ziad; Lustig, Yaniv; Gelman, Boris; Schvartz, Gili; Steinman, Amir

    2017-08-01

    West Nile virus (WNV) epidemiological situation in Israel and Palestine, due to their unique location, draws attention following to the global spread of West Nile fever (WNF). Although much information is available from Israel on clinical cases and prevalence of WNV, clinical cases are rarely reported in Palestine, and prevalence is not known. The objectives of this study were to determine WNV seroprevalence in various domestic animals in Palestine and to reevaluate current seroprevalence, force of infection, and risk factors for WNV exposure in horses in Israel. Sera samples were collected from 717 animals from Palestine and Israel (460 horses, 124 donkeys, 3 mules, 50 goats, 45 sheep, and 35 camels). Two hundred and ten horses were sampled twice. The level of WNV antibodies was determined using commercial Enzyme-linked Immunosorbent Assay (ELISA) Kit. Seroprevalence in equids was 73%. Seroprevalence in Israel (84.6%) was significantly higher than in Palestine (48.6%). Seroprevalence in horses (82.6%) was significantly higher than in donkeys and mules (39.3%). Multivariable statistical analysis showed that geographical area, landscape features (altitude), environmental factors (land surface temperature during the day [LSTD]), species, and age significantly influenced WNV seroprevalence. Fourteen of 95 (14.7%) sheep and goats and 14/35 camels (40%) sampled in Palestine were seropositive for WNV. Of the horses that were sampled twice, 82.8% were seropositive for WNV at the first sampling, and all remained seropositive. Three of the seronegative horses, all from Palestine, converted to positive when resampled (8.5%). The results indicate that domestic animals in Palestine were infected with WNV in the past, and the seroconversion indicates that WNV was circulating in Palestine in the summer of 2014. Control measures to prevent human infection should be implemented in Palestine. Anti WNV antibodies in domestic animals suggest that those species can be used as

  3. Visual communication stimulates reproduction in Nile tilapia, Oreochromis niloticus (L.).

    PubMed

    Castro, A L S; Gonçalves-de-Freitas, E; Volpato, G L; Oliveira, C

    2009-04-01

    Reproductive fish behavior is affected by male-female interactions that stimulate physiological responses such as hormonal release and gonad development. During male-female interactions, visual and chemical communication can modulate fish reproduction. The aim of the present study was to test the effect of visual and chemical male-female interaction on the gonad development and reproductive behavior of the cichlid fish Nile tilapia, Oreochromis niloticus (L.). Fifty-six pairs were studied after being maintained for 5 days under one of the four conditions (N = 14 for each condition): 1) visual contact (V); 2) chemical contact (Ch); 3) chemical and visual contact (Ch+V); 4) no sensory contact (Iso) - males and females isolated. We compared the reproductive behavior (nesting, courtship and spawning) and gonadosomatic index (GSI) of pairs of fish under all four conditions. Visual communication enhanced the frequency of courtship in males (mean +/- SEM; V: 24.79 +/- 3.30, Ch+V: 20.74 +/- 3.09, Ch: 0.1 +/- 0.07, Iso: 4.68 +/- 1.26 events/30 min; P < 0.05, two-way ANOVA with LSD post hoc test), induced spawning in females (3 spawning in V and also 3 in Ch+V condition), and increased GSI in males (mean +/- SEM; V: 1.39 +/- 0.08, Ch+V: 1.21 +/- 0.08, Ch: 1.04 +/- 0.07, Iso: 0.82 +/- 0.07%; P < 0.05, two-way ANOVA with LSD post hoc test). Chemical communication did not affect the reproductive behavior of pairs nor did it enhance the effects of visual contact. Therefore, male-female visual communication is an effective cue, which stimulates reproduction among pairs of Nile tilapia.

  4. Diversification of West Nile virus in a subtropical region

    PubMed Central

    Chisenhall, Daniel M; Mores, Christopher N

    2009-01-01

    Background West Nile virus (WNV) has spread across North, Central, and South America since its introduction in 1999. At the start of this spread, Florida was considered a potentially important area with regards to transmission due to its geographic, climatological, and demographic conditions. Curiously, the anticipated high levels of transmission or disease outbreaks have not been observed. As other studies have predicted that the lack of intense WNV transmission is not due to vector incompetence, we sought to evaluate the role of viral strain diversity in WNV transmission in Florida. Therefore, a phylogentic analysis was carried out on several isolates collected from three distinct locations in Florida. Results Contrasting with a positive control collected in Indian River County, Florida during 2003 that contains the original NY99 genotype with valanine at amino acid 159 of the envelope region, all of the isolates collected in 2005 contain the WN02 genotype composed of a substation with alanine at that position indicating the window of introduction of the WN02 genotype occurred between 2003 and 2005. From the eight isolates collected in Duval, Indian River, and Manatee Counties; there is also a silent nucleotide substitution that differentiates the isolates collected on the Atlantic side of the state compared to the isolate collected on the Gulf side, which groups closer to isolates from other locations near the Gulf. Conclusion As a whole, the Florida isolates contained numerous variable nucleotide and amino acid sites from the reference sequences, as well as each other; indicating greater nucleotide diversity within the Florida 2005 isolates than within other regions. Finally, a series of three amino acid substitutions surrounding a set of histidines located in the envelope coding region that hypothesized to play a role in conformational changes was found in the isolate collected in Indian River County, perhaps changing the antigenicity of the homodimer. Taken

  5. Nile Red binding to HepG2 cells: an improved assay for in vitro studies of hepatosteatosis.

    PubMed

    McMillian, M K; Grant, E R; Zhong, Z; Parker, J B; Li, L; Zivin, R A; Burczynski, M E; Johnson, M D

    2001-01-01

    Nile Red is a fluorescent dye used extensively to study fat accumulation in many types of cells; unfortunately protocols that work well for most cells are not effective for studying drug-induced lipid accumulation in cultured liver cells and hepatocyte-derived cell lines. Using human hepatoma (HepG2) cells, we have developed a simple Nile Red binding assay as a screen for steatosis-inducing compounds. Increases in Nile Red binding in response to known hepatotoxic compounds were observed after incubating treated cells with 1 microM Nile Red for several hours, washing away free Nile Red, and then allowing redistribution, and/or clearance of the lipid-indicator dye. Several compounds known to cause hepatic fat accumulation in vivo were examined and most robustly increased Nile Red binding in HepG2 cells. These include estrogen and other steroids, ethionine, cyclosporin A, and valproic acid. Required concentrations for increased Nile Red binding were generally three-fold or more lower than the cytotoxic concentration determined by a resazurin reduction assay in the same cells. Qualitatively similar Nile Red binding results were obtained when primary canine or rat hepatocytes were used. Morphological differences in Nile Red staining were observed by confocal fluorescence microscopy in HepG2 cells after treatment with different compounds and likely reflect distinct toxicological mechanisms.

  6. Blue-noise multitone dithering.

    PubMed

    Bacca Rodriguez, J; Arce, G R; Lau, D L

    2008-08-01

    The introduction of the blue-noise spectra-high-frequency white noise with minimal energy at low frequencies-has had a profound impact on digital halftoning for binary display devices, such as inkjet printers, because it represents an optimal distribution of black and white pixels producing the illusion of a given shade of gray. The blue-noise model, however, does not directly translate to printing with multiple ink intensities. New multilevel printing and display technologies require the development of corresponding quantization algorithms for continuous tone images, namely multitoning. In order to define an optimal distribution of multitone pixels, this paper develops the theory and design of multitone, blue-noise dithering. Here, arbitrary multitone dot patterns are modeled as a layered superposition of stack-constrained binary patterns. Multitone blue-noise exhibits minimum energy at low frequencies and a staircase-like, ascending, spectral pattern at higher frequencies. The optimum spectral profile is described by a set of principal frequencies and amplitudes whose calculation requires the definition of a spectral coherence structure governing the interaction between patterns of dots of different intensities. Efficient algorithms for the generation of multitone, blue-noise dither patterns are also introduced.

  7. Two Myxobolus spp. infecting the kidney of Nile tilapia (Oreochromis niloticus) in the River Nile at Beni-Suef governorate, Egypt, and the associated renal changes.

    PubMed

    Abdel-Baki, Abdel-Azeem S; Abdel-Haleem, Heba M; Sakran, Thabet; Zayed, Eman; Ibrahim, Khalid E; Al-Quraishy, Saleh

    2015-03-01

    Two Myxobolus spp. are described from the kidney of the Nile tilapia (Oreochromis niloticus) collected from the River Nile, Egypt. The prevalence of infection was 61 % (47/77), with the infected fish in each case parasitized by the two Myxobolus species simultaneously. The infection was exhibited as free spores in Bowman capsules and renal glomeruli, which makes their original structures difficult to discern. In some cases, the infection appeared as a fibrous plasmodia-like structure containing degenerated developmental stages and spores in the interstitium. The paper identifies each species based on the morphological characteristics of its spores and identifies the histological impacts of Myxobolus infection in this species of fish.

  8. Biophysical and financial impacts of community-based gully rehabilitation in the Birr Watershed, Upper Blue Nile Basin, Ethiopia

    USDA-ARS?s Scientific Manuscript database

    Although erosion in the Ethiopian highlands has been occurring for thousands of years, rivers sediment concentration has increased two to three fold during the last fifty years, reducing crop and livestock production and the volume of irrigation water stored in reservoirs. Gully erosion in particula...

  9. Agminated blue nevus - Case report*

    PubMed Central

    Lisboa, Alice Paixão; Silvestre, Keline Jácome; Pedreira, Renata Leite; Alves, Natália Ribeiro de Magalhães; Obadia, Daniel Lago; Azulay-Abulafia, Luna

    2016-01-01

    Blue nevi are benign melanocytic lesions located in the deeper reticular dermis, consequence of failure of melanocytic migration into the dermal-epidermal junction from the neural crest. Lesions are usually asymptomatic and solitary, but may present in a multiple or agminated (grouped) pattern. The agminated subtype is formed when bluish-pigmented lesions cluster together in a well-defined area. Lesions can be flat or raised. We report the case of a patient who presented multiple bluish macules (1-3 mm in diameter) grouped on the left upper back. Dermoscopy and anatomic pathological examination were consistent with blue nevus. PMID:27828645

  10. Blue-green upconversion laser

    DOEpatents

    Nguyen, D.C.; Faulkner, G.E.

    1990-08-14

    A blue-green laser (450--550 nm) uses a host crystal doped with Tm[sup 3+]. The Tm[sup 3+] is excited through upconversion by a red pumping laser and an IR pumping laser to a state which transitions to a relatively lower energy level through emissions in the blue-green band, e.g., 450.20 nm at 75 K. The exciting laser may be tunable dye lasers or may be solid-state semiconductor laser, e.g., GaAlAs and InGaAlP. 3 figs.

  11. Blue-green upconversion laser

    SciTech Connect

    Nguyen, Dinh C.; Faulkner, George E.

    1990-01-01

    A blue-green laser (450-550 nm) uses a host crystal doped with Tm.sup.3+. The Tm.sup.+ is excited through upconversion by a red pumping laser and an IR pumping laser to a state which transitions to a relatively lower energy level through emissions in the blue-green band, e.g., 450.20 nm at 75 K. The exciting laser may be tunable dye lasers or may be solid-state semiconductor laser, e.g., GaAlAs and InGaAlP.

  12. Blue light emitting thiogallate phosphor

    DOEpatents

    Dye, Robert C.; Smith, David C.; King, Christopher N.; Tuenge, Richard T.

    1998-01-01

    A crystalline blue emitting thiogallate phosphor of the formula RGa.sub.2 S.sub.4 :Ce.sub.x where R is selected from the group consisting of calcium, strontium, barium and zinc, and x is from about 1 to 10 atomic percent, the phosphor characterized as having a crystalline microstructure on the size order of from about 100 .ANG. to about 10,000 .ANG. is provided together with a process of preparing a crystalline blue emitting thiogallate phosphor by depositing on a substrate by CVD and resultant thin film electroluminescent devices including a layer of such deposited phosphor on an ordinary glass substrate.

  13. The Blue-Collar Brain

    PubMed Central

    Van Orden, Guy; Hollis, Geoff; Wallot, Sebastian

    2012-01-01

    Much effort has gone into elucidating control of the body by the brain, less so the role of the body in controlling the brain. This essay develops the idea that the brain does a great deal of work in the service of behavior that is controlled by the body, a blue-collar role compared to the white-collar control exercised by the body. The argument that supports a blue-collar role for the brain is also consistent with recent discoveries clarifying the white-collar role of synergies across the body’s tensegrity structure, and the evidence of critical phenomena in brain and behavior. PMID:22719730

  14. An ancient icon reveals new mysteries: mummy DNA resurrects a cryptic species within the Nile crocodile.

    PubMed

    Hekkala, Evon; Shirley, Matthew H; Amato, George; Austin, James D; Charter, Suellen; Thorbjarnarson, John; Vliet, Kent A; Houck, Marlys L; Desalle, Rob; Blum, Michael J

    2011-10-01

    The Nile crocodile (Crocodylus niloticus) is an ancient icon of both cultural and scientific interest. The species is emblematic of the great civilizations of the Nile River valley and serves as a model for international wildlife conservation. Despite its familiarity, a centuries-long dispute over the taxonomic status of the Nile crocodile remains unresolved. This dispute not only confounds our understanding of the origins and biogeography of the 'true crocodiles' of the crown genus Crocodylus, but also complicates conservation and management of this commercially valuable species. We have taken a total evidence approach involving phylogenetic analysis of mitochondrial and nuclear markers, as well as karyotype analysis of chromosome number and structure, to assess the monophyletic status of the Nile crocodile. Samples were collected from throughout Africa, covering all major bioregions. We also utilized specimens from museum collections, including mummified crocodiles from the ancient Egyptian temples at Thebes and the Grottes de Samoun, to reconstruct the genetic profiles of extirpated populations. Our analyses reveal a cryptic evolutionary lineage within the Nile crocodile that elucidates the biogeographic history of the genus and clarifies long-standing arguments over the species' taxonomic identity and conservation status. An examination of crocodile mummy haplotypes indicates that the cryptic lineage corresponds to an earlier description of C. suchus and suggests that both African Crocodylus lineages historically inhabited the Nile River. Recent survey efforts indicate that C. suchus is declining or extirpated throughout much of its distribution. Without proper recognition of this cryptic species, current sustainable use-based management policies for the Nile crocodile may do more harm than good. © 2011 Blackwell Publishing Ltd.

  15. Seasonal fluctuation and histopathology of Henneguya ghaffari (Myxozoa: Myxosporea) infection in the gills of the Nile perch, Lates niloticus, in the River Nile: a new locality record.

    PubMed

    Abdel-Baki, Abdel-Azeem S; Sakran, Thabet; Zayed, Eman; Al-Quraishy, Saleh

    2014-04-01

    Henneguya ghaffari Ali (Dis Aquat Org 38:225-230, 1999), which was originally described in Lake Wadi El-Rayan in the western desert of Egypt, has been discovered in the gills of the Nile perch, Lates niloticus, sourced from the River Nile at Beni-Suef governorate. The species identification was based on the spore morphometry. Of 180 Nile perch, 68 were found to be naturally infected with H. ghaffari (37.7%). A significant seasonal fluctuation in the prevalence was discerned, with the maximum rate occurring in the winter (68.8%) and the minimum rate in the summer (8.8%). The plasmodia of the parasite were evident as white rods, occupying almost a third of the gill filament and with mean dimensions of 0.7 × 0.2 mm. Histological investigations revealed that the present plasmodia were potentially compatible with the intrafilamental type. Infection with H. ghaffari initiated epithelial hyperplasia and curling and atrophy of the respiratory lamellae, which underpin its deleterious effect on the host by decreasing the functional respiratory surface of the gills. The present study concluded that infection with H. ghaffari originated in the River Nile before moving to the new ecosystem of Lake Wadi El-Rayan through drainage water.

  16. Singing' the Black and Blues

    ERIC Educational Resources Information Center

    Fisher, Diane

    2004-01-01

    It is so obvious that the sky is blue in the daytime and black at night, but it took the smartest humans thousands of years of observation, thought, discussion, conjecture, and analysis to finally come up with answers that make scientific sense as to why the sky is these colors. This article discusses light and the scientific research…

  17. The Taos Blue Lake Ceremony.

    ERIC Educational Resources Information Center

    Bodine, John J.

    1988-01-01

    Describes the Blue Lake Ceremony of the Taos Pueblo Indians of New Mexico. Reproduces the 1906 account of the ceremony by anthropologist Matilda Coxe Stevenson and notes modern verification and change. Discusses the importance of this annual August pilgrimage and initiation rite to the preservation of Taos culture. (SV)

  18. Singing' the Black and Blues

    ERIC Educational Resources Information Center

    Fisher, Diane

    2004-01-01

    It is so obvious that the sky is blue in the daytime and black at night, but it took the smartest humans thousands of years of observation, thought, discussion, conjecture, and analysis to finally come up with answers that make scientific sense as to why the sky is these colors. This article discusses light and the scientific research…

  19. Nobel Prize for blue LEDs

    NASA Astrophysics Data System (ADS)

    Kraftmakher, Yaakov

    2015-05-01

    A brief review of lighting technologies is presented. Unavoidable restrictions for incandescent light bulbs caused by the Planck distribution and properties of the human eye are illustrated. The efficiency and luminous efficacy of thermal radiation are calculated for various temperatures; the results clearly show the limitations for thermal radiators. The only way to overcome these limitations is using non-thermal radiators, such as fluorescent lamps and light-emitting diodes (LEDs). Unique advantages of LEDs undoubtedly made a revolution in this field. A crucial element of this progress is the blue LEDs (Nobel Prize 2014). Some experiments with a blue and a green LED are described: (i) the luminescence triggered in a green-yellow phosphor inside a white LED by the blue LED; (ii) radiant spectra and ‘efficiency droop’ in the LEDs; (iii) modulation of the blue LED up to 4 MHz; and (iv) the h/e ratio from the turn-on voltage of the green LED. The experiments are suitable for undergraduate laboratories and usable as classroom demonstrations.

  20. Blue dextran-mediated hemagglutination.

    PubMed

    Imanishi, K; Suzuki, I

    1982-01-01

    Blue dextran at low concentrations (0.1-1 ng/ml) agglutinated human, mouse, rabbit and rat erythrocytes. This agglutination was inhibited by 10% calf serum, 0.5 mg/ml bovine albumin and 0.2 M sodium thiocyanate, and less effectively by 1.5 M potassium chloride, but not by 30-50 mM magnesium sulfate.

  1. Teaching Sherman Alexie's "Reservation Blues."

    ERIC Educational Resources Information Center

    McFarland, Ronald E.

    2001-01-01

    A college teacher discusses his experiences of departing from the established literary canon to teach Sherman Alexie's "Reservation Blues" as part of an upper-level American literature survey class. Students reacted to the novel and its characters, evaluated Alexie's writing techniques, and discussed their personal experiences with Native…

  2. Methyl blue and aniline blue versus patent blue and trypan blue as vital dyes in cataract surgery: capsule staining properties and cytotoxicity to human cultured corneal endothelial cells.

    PubMed

    Thaler, Sebastian; Hofmann, Johanna; Bartz-Schmidt, Karl-Ulrich; Schuettauf, Frank; Haritoglou, Christos; Yoeruek, Efdal

    2011-06-01

    To evaluate capsule-staining properties and biocompatibility of the triarylmethane dyes methyl blue and aniline blue compared with patent blue and trypan blue on cultured human corneal endothelial cells. Centre for Ophthalmology, University of Tuebingen, Tuebingen, Germany. Experimental study. Human corneal endothelial cell cultures were harvested from human donor cells and exposed to various concentrations (0.025 to 5.0 mg/mL) of methyl blue, aniline blue, patent blue, and trypan blue. Cytotoxicity was assessed by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide test after 24 hours of incubation. Calcein live cell staining was performed at the same time point. The dyes were also used to stain pig lens capsules in vitro by incubating the lenses for 1 minute with 3 concentrations (0.5, 1.5, and 2.5 mg/mL) of dye, after which the staining properties were evaluated. No significant cytotoxicity was detected for patent blue and methyl blue at any tested concentration. However, aniline blue exerted significant cytotoxicity at concentrations of 1.5 mg/mL or higher and trypan blue at 2.5 mg/mL or higher. Capsule staining of the tested triarylmethane dyes was suitable for performing capsulorhexis, but only at higher concentrations than with trypan blue. High concentrations and long incubation times of trypan blue and aniline blue showed significant cytotoxicity to human cultured endothelial cells in contrast to patent blue and methyl blue. All tested dyes were able to stain lens capsules sufficiently for capsulorhexis creation. No author has a financial or proprietary interest in any material or method mentioned. Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  3. Identification of impacts on the Egyptian Nile using remote sensing and GIS

    NASA Astrophysics Data System (ADS)

    El-Nahry, A. H.

    2013-10-01

    Nile River, the longest river in the world, 6,695 km long from its remotest headstream, the Luvironza River in Burundi, central Africa, to its delta on the Mediterranean Sea, NE Egypt. The Nile River islands form an attractive agricultural area characterized with its nightly fertile soils, easy source, and its suitability to a wide range of land use. The present use of these Nile islands does not reach the maximum capability of these resources due to improper land use of these areas.The current study aims at identifying the changes of the Nile course and its islands during the last three decades using remote sensing and GIS techniques in order to provide the scientific bases, which help in planning the most suitable programs of land use, soil management and conservation. Six MSS, eight TM and Eight ETM+ satellite images dated to 1972,1984 and 2002 respectively were used to study the changes occurred during the above-mentioned periods. The study area was divided into five sectors along the Nile River course i.e. Aswan - Qena, Qena - Assiut , Assiut - Qalubia , Qalubia - Damietta and Qalubia - Rosetta . The changes in Nile course from early seventieth to middle eighteenth were decreased by 51.34 Km2, from middle eighteenth to the millennium were decreased by 40.30 Km2. The overall change in Nile course area decreased by 91.64 Km2 in the investigation period. Belonging to the islands number and their areas in the investigation period, the changes in islands number from early seventieth to middle eighteenth were increased by 171 islands, from middle eighteenth to the millennium were decreased by 86 islands. Meanwhile, the islands areas from early seventieth to middle eighteenth were decreased by 4512.39 Feddan., from middle eighteenth to the millennium were decreased by 5446.97 Feddan. The overall change in the investigation period for the total number of the islands was increased by 85 islands, meanwhile the islands areas were decreased by 9959.36 Feddan. Changes of

  4. Quantification of River Nile/Quaternary aquifer exchanges via riverbank filtration by hydrochemical and biological indicators, Assiut, Egypt

    NASA Astrophysics Data System (ADS)

    Abdalla, Fathy; Shamrukh, Mohamed

    2016-12-01

    This study approach seeks to characterize the hydraulic interactions between the Nile and the Quaternary aquifer via riverbank filtration (RBF) in Abu Tieg area, Assuit Governorate. The substantial removal/reduction of the most problematic substances during percolation of Nile water into abstraction wells was investigated using physico-chemical and biological indicators. Four sites with 11 municipal wells (20-750 m from the Nile) tapping the alluvial aquifer that is fed by the riverbank infiltrate were monitored. Bank-filtrated water was compared with those of the Nile and groundwater. Results showed that infiltrated Nile water ratio into the wells ranged from 39 to 80% reflecting the effect of distance from the Nile. Removal efficiency of total algal, total and faecal coliforms in bank-filtered water was 99.9%, while turbidity removal ranged from 93 to 98%. Fe, Mn and Zn in the bank-filtered water were relatively higher than those in the Nile, but were still under the allowable standards except those of Mn. LSI and WQI for the bank-filtered water indicated that the water was ranked as non-corrosive and of excellent quality. Comparison of physico-chemical and microbiological characteristics of the bank-filtered water with those of the Nile and groundwater showed the high efficiency of RBF as a treatment technology with minimal cost compared to conventional methods.

  5. Identification and transcriptional profile of multiple genes in the posterior kidney of Nile tilapia at 6h post bacterial infections

    USDA-ARS?s Scientific Manuscript database

    To understand the molecular mechanisms involved in response of Nile tilapia (Oreochromis niloticus) to bacterial infection, suppression subtractive cDNA hybridization technique was used to identify upregulated genes in the posterior kidney of Nile tilapia at 6h post infection with Aeromonas hydrophi...

  6. BIOLOG MICROLOG® IDENTIFICATION OF Lactococcus garvieae INFECTION IN NILE TILAPIA Oreochromis niloticus AND PINTADO Pseudoplathystoma corruscans FROM BRAZIL

    USDA-ARS?s Scientific Manuscript database

    Lactococcus garvieae infection in cultured Nile tilapia, Oreochromis niloticus, and pintado, Pseudoplathystoma corruscans from Brazil is reported. This is the first evidence of the presence of this pathogen from Brazilian fish and the first report of L. garvieae infection in either Nile tilapia or ...

  7. 21 CFR 133.106 - Blue cheese.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... methods described in § 133.5. The dairy ingredients used may be pasteurized. Blue cheese is at least 60... ingredients. (i) Blue or green color in an amount to neutralize the natural yellow color of the curd....

  8. The Blues Poetry of Langston Hughes

    ERIC Educational Resources Information Center

    Waldron, Edward E.

    1971-01-01

    The author discusses the criteria of the blues as an American art form. He then shows how Langston Hughes captures the mood, the feeling, the rhythm and the impact of the blues in his poetry. (Author/LF)

  9. 21 CFR 73.50 - Ultramarine blue.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... ultramarine blue is a blue pigment obtained by calcining a mixture of kaolin, sulfur, sodium carbonate, and... order to vary the shade. The pigment is a complex sodium aluminum sulfo-silicate having the...

  10. 21 CFR 73.50 - Ultramarine blue.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... ultramarine blue is a blue pigment obtained by calcining a mixture of kaolin, sulfur, sodium carbonate, and... order to vary the shade. The pigment is a complex sodium aluminum sulfo-silicate having the...

  11. 21 CFR 73.50 - Ultramarine blue.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ultramarine blue is a blue pigment obtained by calcining a mixture of kaolin, sulfur, sodium carbonate, and... order to vary the shade. The pigment is a complex sodium aluminum sulfo-silicate having the...

  12. 21 CFR 73.50 - Ultramarine blue.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... ultramarine blue is a blue pigment obtained by calcining a mixture of kaolin, sulfur, sodium carbonate, and... order to vary the shade. The pigment is a complex sodium aluminum sulfo-silicate having the...

  13. 21 CFR 73.50 - Ultramarine blue.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... ultramarine blue is a blue pigment obtained by calcining a mixture of kaolin, sulfur, sodium carbonate, and... order to vary the shade. The pigment is a complex sodium aluminum sulfo-silicate having the...

  14. Practical utility of the blue spectral region

    NASA Technical Reports Server (NTRS)

    Ross, D. S.

    1972-01-01

    Some aspects of multispectral photography in the blue region are discussed briefly, and sample images are submitted to demonstrate the potential utility of the blue multispectral record for oceanography.

  15. European Surveillance for West Nile Virus in Mosquito Populations

    PubMed Central

    Engler, Olivier; Savini, Giovanni; Papa, Anna; Figuerola, Jordi; Groschup, Martin H.; Kampen, Helge; Medlock, Jolyon; Vaux, Alexander; Wilson, Anthony J.; Werner, Doreen; Jöst, Hanna; Goffredo, Maria; Capelli, Gioia; Federici, Valentina; Tonolla, Mauro; Patocchi, Nicola; Flacio, Eleonora; Portmann, Jasmine; Rossi-Pedruzzi, Anya; Mourelatos, Spiros; Ruiz, Santiago; Vázquez, Ana; Calzolari, Mattia; Bonilauri, Paolo; Dottori, Michele; Schaffner, Francis; Mathis, Alexander; Johnson, Nicholas

    2013-01-01

    A wide range of arthropod-borne viruses threaten both human and animal health either through their presence in Europe or through risk of introduction. Prominent among these is West Nile virus (WNV), primarily an avian virus, which has caused multiple outbreaks associated with human and equine mortality. Endemic outbreaks of West Nile fever have been reported in Italy, Greece, France, Romania, Hungary, Russia and Spain, with further spread expected. Most outbreaks in Western Europe have been due to infection with WNV Lineage 1. In Eastern Europe WNV Lineage 2 has been responsible for human and bird mortality, particularly in Greece, which has experienced extensive outbreaks over three consecutive years. Italy has experienced co-circulation with both virus lineages. The ability to manage this threat in a cost-effective way is dependent on early detection. Targeted surveillance for pathogens within mosquito populations offers the ability to detect viruses prior to their emergence in livestock, equine species or human populations. In addition, it can establish a baseline of mosquito-borne virus activity and allow monitoring of change to this over time. Early detection offers the opportunity to raise disease awareness, initiate vector control and preventative vaccination, now available for horses, and encourage personal protection against mosquito bites. This would have major benefits through financial savings and reduction in equid morbidity/mortality. However, effective surveillance that predicts virus outbreaks is challenged by a range of factors including limited resources, variation in mosquito capture rates (too few or too many), difficulties in mosquito identification, often reliant on specialist entomologists, and the sensitive, rapid detection of viruses in mosquito pools. Surveillance for WNV and other arboviruses within mosquito populations varies between European countries in the extent and focus of the surveillance. This study reviews the current status of

  16. Yard flooding by irrigation canals increased the risk of West Nile disease in El Paso, Texas

    PubMed Central

    Cardenas, Victor M.; Jaime, Javier; Ford, Paula B.; Gonzalez, Fernando J.; Carrillo, Irma; Gallegos, Jorge E.; Watts, Douglas M.

    2011-01-01

    Purpose To investigate the effects of use of water from irrigation canals to flood residential yards on the risk of West Nile disease in El Paso, Texas. Methods West Nile disease confirmed cases in 2009–2010 were compared with a random sample of 50 residents of the county according to access to and use of water from irrigation canals by subjects or their neighbors, as well as geo-referenced closest distance between their home address and the nearest irrigation canal. A windshield survey of 600 meters around the study subjects’ home address recorded the presence of irrigation canals. The distance from the residence of 182 confirmed cases of West Nile disease reported in 2003–2010 to canals was compared to that of the centroids of 182 blocks selected at random. Results Cases were more likely than controls to report their neighbors flooded their yards with water from canals. Irrigation canals were more often observed in neighborhoods of cases than of controls. Using the set of addresses of 182 confirmed cases and 182 hypothetic controls the authors found a statistically significant inverse relation with risk of West Nile disease. Conclusions Flooding of yards with water from canals increased the risk of West Nile disease. PMID:21943648

  17. Hydrology and empire: the Nile, water imperialism and the partition of Africa.

    PubMed

    Tvedt, Terje

    2011-01-01

    Why did the British march up the Nile in the 1890s? The answers to this crucial question of imperial historiography have direct relevance for narratives and theories about imperialism, in general, and the partition of Africa in the nineteenth century, in particular. They will also influence our understanding of some of the main issues in the modern history of the whole region, including state developments and resource utilisation. This article presents an alternative to dominant interpretations of the partition of Africa and the role of British Nile policies in this context. It differs from mainstream diplomatic history, which dominates this research field, in its emphasis on how geographical factors and the hydrological characteristics of the Nile influenced and framed British thinking and actions in the region. Realising the importance of such factors and the specific character of the regional water system does not imply less attention to traditional diplomatic correspondence or to the role of individual imperial entrepreneurs. The strength of this analytical approach theoretically is that it makes it possible to locate the intentions and acts of historical subjects within specific geographical contexts. Empirically, it opens up a whole new set of source material, embedding the reconstruction of the British Nile discourse in a world of Nile plans, water works and hydrological discourses.

  18. Egyptian mummies record increasing aridity in the Nile valley from 5500 to 1500 yr before present

    NASA Astrophysics Data System (ADS)

    Touzeau, Alexandra; Blichert-Toft, Janne; Amiot, Romain; Fourel, François; Martineau, François; Cockitt, Jenefer; Hall, Keith; Flandrois, Jean-Pierre; Lécuyer, Christophe

    2013-08-01

    Oxygen isotope compositions were measured in teeth (n=29) and bones (n=41) from Egyptian mummies of humans (n=48) in order to track the δ18O evolution of the Nile from 5500 to 1500 B.P. The combination of δ18O values of apatite carbonate and phosphate was used to filter the database for post mortem alteration of bioapatites, while 87Sr/86Sr ratios were used to detect potential allochthonous people buried in the various archeological sites located along the Nile. This approach led to only five apatite samples out of seventy to be discarded from the database. The remaining oxygen isotope compositions of both tooth and bone phosphates from ancient Egyptians were converted into the composition of ingested water ultimately originating from the Nile. It was found that δ18O of Nile waters increases progressively from -1.6 to +1.5 (‰ VSMOW) from the Predynastic (∼5500 B.P.) through the Late Period (∼2550 B.P.). This trend towards higher Nile δ18O values acquired in more recent times is coherent with a general drying trend in Northeast Africa, which was not limited to a drying spell at the end of the Nabtian Pluvial (ca. 12,000 B.P. -ca. 6000 B.P.), but extended far into the following millennia nearly to the beginning of the Common Era (1950 B.P.).

  19. Impact of climate change on water and agriculture: Challenges and possible solutions for the Nile Delta

    NASA Astrophysics Data System (ADS)

    Mabrouk, Badr; Arafa, Salah; Farahat, Hany; Badr, Marmar; Gampe, David; Ludwig, Ralf

    2013-04-01

    The Nile-Delta is subjected to continuous changes; including shoreline changes either erosion or accretion, subsidence of the delta, as well as sea level rise due to climate change. The impacts of climate change on the Nile Delta have been addressed on local and international level as the Nile Delta coastal zones are vulnerable to sea level rise. The poster presents recent research activities and findings from the CLIMB project in the Nile Delta and costal zones of Egypt. Lots of field data have been collected such as aquifer geometry data, soil properties data, well data and contamination sources. All of these data support a coupled modeling approach of the land surface hydrological model WASIM-ETH and the hydrological model MOD-Flow to simulate and project the future impact translation of climate projections into hydrological impacts. Results confirm intensified threads to water security. Increasing potential evaporation (in response to increasing temperature) in combination with decreasing water levels in the Nile river, reduced precipitation and groundwater recharge and deteriorating groundwater quality, imposes great challenges to ensure the supply of drinking water and irrigation. Current irrigation strategies are highly inefficient and must be replaced by new and adapted systems. Based on the results of the coupled modeling approach, various scenarios can be evaluated. The vision is to develop a road map for climate change and green economy that maximizes wellbeing of the Egyptian citizens, operates with environmental limits, and is capable of adapting to global environmental change.

  20. Investigation of antiaromatase activity using hepatic microsomes of Nile tilapia (Oreochromis niloticus).

    PubMed

    Sassa-Deepaeng, Tanongsak; Chaisri, Wasana; Pikulkaew, Surachai; Okonogi, Siriporn

    2017-03-19

    Microsomal aromatase enzymes of humans and rats have been used in antiaromatase assays, but enzyme activity is species-specific. The current study extracted hepatic microsomes of Nile tilapia (Oreochromis niloticus) to investigate and compare the antiaromatase activity of chrysin, quercetin, and quercitrin. This activity was evaluated using a dibenzylfluorescein (DBF) assay. Results revealed that the age and body weight of Nile tilapia affected the yield of extracted microsomes. Extraction of hepatic microsomes of Nile tilapia was most effective when using a reaction medium with a pH of 8.0. A DBF assay using Nile tilapia microsomes revealed significant differences in levels of antiaromatase activity for chrysin, quercetin, and quercitrin. Chrysin was the most potent aromatase inhibitor, with an IC50 of 0.25 mg/mL. In addition, chrysin is an aromatase inhibitor that also inhibits the proliferation of cancer cells. Hepatic microsomes of Nile tilapia can be used to investigate and compare the antiaromatase activity of different compounds.

  1. Long-Term Neurological Outcomes in West Nile Virus–Infected Patients: An Observational Study

    PubMed Central

    Weatherhead, Jill E.; Miller, Vicki E.; Garcia, Melissa N.; Hasbun, Rodrigo; Salazar, Lucrecia; Dimachkie, Mazen M.; Murray, Kristy O.

    2015-01-01

    The Houston West Nile Cohort (HWNC) was founded in 2002 when West Nile virus (WNV) reached Houston, TX. The long-term outcomes following WNV infection are still mostly unknown, though neurological abnormalities up to 1 year postinfection have been documented. We report an observational study of neurological abnormalities at 1–3 and 8–11 years following WNV infection in the HWNC. We conducted standard neurological examinations at two separate time points to assess changes in neurological status over time. The majority of patients (86%, 30/35) with encephalitis had abnormal neurological exam findings at the time of the first assessment compared with uncomplicated fever (27%, 3/11) and meningitis (36%, 5/14) cases. At the time of the second assessment, 57% (4/7) of West Nile fever (WNF), 33% (2/6) of West Nile meningitis (WNM), and 36% (5/14) of West Nile encephalitis (WNE) had developed new neurological complications. The most common abnormalities noted were tandem gait, hearing loss, abnormal reflexes, and muscle weakness. Long-term neurological abnormalities were most commonly found in patients who experienced primary WNV encephalitis. New abnormalities may develop over time regardless of initial clinical infection. Future studies should aim to differentiate neurological consequences due to WNV neuroinvasive infection versus neurological decline related to comorbid conditions. PMID:25802426

  2. Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes

    SciTech Connect

    Kanai,R.; Kar, K.; Anthony, K.; Gould, L.; Ledizet, M.; Fikrig, E.; Marasco, W.; Koski, R.; Modis, Y.

    2006-01-01

    West Nile virus, a member of the Flavivirus genus, causes fever that can progress to life-threatening encephalitis. The major envelope glycoprotein, E, of these viruses mediates viral attachment and entry by membrane fusion. We have determined the crystal structure of a soluble fragment of West Nile virus E. The structure adopts the same overall fold as that of the E proteins from dengue and tick-borne encephalitis viruses. The conformation of domain II is different from that in other prefusion E structures, however, and resembles the conformation of domain II in postfusion E structures. The epitopes of neutralizing West Nile virus-specific antibodies map to a region of domain III that is exposed on the viral surface and has been implicated in receptor binding. In contrast, we show that certain recombinant therapeutic antibodies, which cross-neutralize West Nile and dengue viruses, bind a peptide from domain I that is exposed only during the membrane fusion transition. By revealing the details of the molecular landscape of the West Nile virus surface, our structure will assist the design of antiviral vaccines and therapeutics.

  3. Yard flooding by irrigation canals increased the risk of West Nile disease in El Paso, Texas.

    PubMed

    Cardenas, Victor M; Jaime, Javier; Ford, Paula B; Gonzalez, Fernando J; Carrillo, Irma; Gallegos, Jorge E; Watts, Douglas M

    2011-12-01

    To investigate the effects of use of water from irrigation canals to flood residential yards on the risk of West Nile disease in El Paso, Texas. West Nile disease confirmed cases in 2009 through 2010 were compared with a random sample of 50 residents of the county according to access to and use of water from irrigation canals by subjects or their neighbors, as well as geo-referenced closest distance between their home address and the nearest irrigation canal. A windshield survey of 600 m around the study subjects' home address recorded the presence of irrigation canals. The distance from the residence of 182 confirmed cases of West Nile disease reported in 2003 through 2010 to canals was compared with that of the centroids of 182 blocks selected at random. Cases were more likely than controls to report their neighbors flooded their yards with water from canals. Irrigation canals were more often observed in neighborhoods of cases than of controls. Using the set of addresses of 182 confirmed cases and 182 hypothetical controls the authors found a significant, inverse relation with risk of West Nile disease. Flooding of yards with water from canals increased the risk of West Nile disease. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes▿

    PubMed Central

    Kanai, Ryuta; Kar, Kalipada; Anthony, Karen; Gould, L. Hannah; Ledizet, Michel; Fikrig, Erol; Marasco, Wayne A.; Koski, Raymond A.; Modis, Yorgo

    2006-01-01

    West Nile virus, a member of the Flavivirus genus, causes fever that can progress to life-threatening encephalitis. The major envelope glycoprotein, E, of these viruses mediates viral attachment and entry by membrane fusion. We have determined the crystal structure of a soluble fragment of West Nile virus E. The structure adopts the same overall fold as that of the E proteins from dengue and tick-borne encephalitis viruses. The conformation of domain II is different from that in other prefusion E structures, however, and resembles the conformation of domain II in postfusion E structures. The epitopes of neutralizing West Nile virus-specific antibodies map to a region of domain III that is exposed on the viral surface and has been implicated in receptor binding. In contrast, we show that certain recombinant therapeutic antibodies, which cross-neutralize West Nile and dengue viruses, bind a peptide from domain I that is exposed only during the membrane fusion transition. By revealing the details of the molecular landscape of the West Nile virus surface, our structure will assist the design of antiviral vaccines and therapeutics. PMID:16943291

  5. [Postpartum blues - a Czech adaptation of the Maternity Blues Questionnaire].

    PubMed

    Takács, L; Smolík, F; Mlíková Seidlerová, J; Čepický, P; Hoskovcová, S

    To validate the Kennerley and Gaths Maternity Blues Questionnaire (MBQ) for the Czech postpartum population, to present the psychometric properties of the Czech version of that screening method, and to assess its predictive power for the risk of postpartum depression. Original study. Department of Psychology, Faculty of Arts and Philosophy, Charles University, Prague. The Czech version of the MBQ was validated on a sample of 1093 women. The data were collected from October 2013 to September 2014 at all maternity hospitals in Vysočina region. The MBQ was administered on a one-time basis during womens postpartal stay at maternity hospital. After six weeks post partum, a screening for postpartum depression was performed using the Edinburgh Postnatal Depression Scale (EPDS). The cut-off point was set at 10/11 for MBQ and 12/13 for EPDS as such were the respective levels achieved by the 90th percentile in the MBQ and EPDS scores. The sociodemografic data were collected at the time of completing the MBQ. A logistic regression was performed to identify the predictors of severe blues. Cronbachs alpha was calculated to assess the internal consistency of the MBQ as a whole and its component scales. In order to assess the validity of the MBQ, a logistic regression was used to analyze the association between the MBQ and EPDS scores. The norms for the Czech version of MBQ are presented as percentiles. The MBQ scores showed a gradual rise over the days following the delivery (day 0 to day 4). The percentage of women with severe blues (MBQ score > 10) increased from 7.3% to 14.55% between day 0 and day 4. The most frequent feelings and mood states experienced by women in the first postpartum days included tiredness (61%), decreased self-confidence (30%), over-sensitivity (26%) and tension (19%), while 6,5% of women felt low spirited and 7% felt depressed. The women suffering from severe blues reported most frequently the same states of mood as did the women in the whole sample

  6. Estimation of Some Bio-Physical Indicators for Sustainable Crop Production in the Eastern Nile Basin of Sudan Using Landsat-8 Imagery and SEBAL Model

    NASA Astrophysics Data System (ADS)

    Guma Biro Turk, Khalid

    2016-07-01

    Crop production under modern irrigation systems require unique management at field level and hence better utilization of agricultural inputs and water resources. This study aims to make use of remote sensing (RS) data and the surface energy balance algorithm for land (SEBAL) to improve the on-farm management. The study area is located in the Eastern part of the Blue Nile River about 60 km south of Khartoum, Sudan. Landsat-8 data were used to estimate a number of bio-physical indicators during the growing season of the year 2014/2015. Accordingly, in-situ weather data and SEBAL model were applied to calculate: the reference (ET0), actual (ETa) and potential (ETp) evapotranspiration, soil moisture (SM), crop factor (kc), nitrogen (N), biomass production (BP) and crop water productivity (CWP). Results revealed that ET0 showed steady variation throughout the year, varying from 5 to 7 mm/day. However, ETa and ETp showed clear temporal variation attributed to frequent cutting of the alfalfa, almost monthly. The BP of the alfalfa was observed to be high when there is no cutting activates were made before the image acquisition date. Nevertheless the CWP trends are following the biomass production ones, low when there is no biomass and high when the biomass is high. The application of SEBAL model within the study area using the Landsat-8 imagery indicates that it's possible to produce field-based bio-physical indicators, which can be useful in monitoring and managing the field during the growing season. However, a cross-calibration with the in-situ data should be considered in order to maintain the spatial variability within the field. Keywords: Bio-physical Indicators; Remote Sensing; SEBAL; Landsat-8; Eastern Nile Basin

  7. Paleoclimate of the Eastern Mediterranean/North Africa during the past 26 cal ka based on organic geochemical investigations of a Nile River Delta sediment core

    NASA Astrophysics Data System (ADS)

    Castaneda, I. S.; Schefuss, E.; Patzold, J.; Sinninghe Damste, J. S.; Schouten, S.

    2007-12-01

    The Mediterranean Sea is situated within a highly sensitive climatic region, which is influenced by both tropical and mid-latitude climate dynamics, and the paleoenvironmental history of this region is of interest because large human populations occupy the surrounding landmasses. In this study, multiple organic geochemical proxies are examined from a Nile River Delta sediment core (GeoB 7702-3) to investigate the paleoclimatic history of the North Africa/Eastern Mediterranean region during the past ~26 cal ka. Sea surface temperatures were reconstructed using both the TEX86 and alkenone paleothermometers. The TEX86 record exhibits centennial to millennial scale variability and captures global climate events including the Last Glacial Maximum (LGM), Heinrich Event 1 (H1), the Bolling/Allerod and the Younger Dryas (YD). The recently developed Branched and Isoprenoid Tetraether (BIT) index, used to differentiate between marine and terrestrial inputs, closely tracks changes noted in bulk C/N ratios. Overall, these records indicate greater variability during the Late Pleistocene than during the Holocene, with the highest terrestrial inputs noted at approximately the time of the YD and prior to H1. Although it might be expected that fluvial organic matter inputs should be the lowest during the LGM, when the sources of both the Blue and White Nile were severely reduced or desiccated, higher (more terrestrial) BIT values noted at these times may be related to changes in vegetation cover in North Africa. During the Holocene, a major shift in the BIT index to lower (more marine) values marks the onset of deposition of the S1 sapropel layer. The lower BIT values noted during this interval are caused by a dramatic (order of magnitude) increase in the absolute abundance of crenarchaeol, attesting to enhanced marine productivity at this time. Following deposition of the S1 sapropel, absolute abundances of crenarchaeol are generally higher than during the Late Pleistocene

  8. On Seeing Reddish Green and Yellowish Blue.

    ERIC Educational Resources Information Center

    Crane, Hewitt D.; Piantanida, Thomas P.

    1983-01-01

    Stabilization of the retinal image of the boundary between a pair of red/green or yellow/blue stripes, but not their outer edges, results in the entire region being perceived simultaneously as both red/green or yellow/blue. This suggests that the percepts of reddish-green/yellowish-blue apparently are possible in corticocortical color vision…

  9. A new rhythm for the Blues.

    PubMed

    Tokarski, C

    1995-03-05

    If 1994 was the year the nation's Blue Cross and Blue Shield plans surpassed their managed care competitors in enrollment, 1995 is shaping up to be the year the Blues lead the stampede to form integrated delivery systems. Plus, a look at the new BC/BS chief, Patrick Hays.

  10. On Seeing Reddish Green and Yellowish Blue.

    ERIC Educational Resources Information Center

    Crane, Hewitt D.; Piantanida, Thomas P.

    1983-01-01

    Stabilization of the retinal image of the boundary between a pair of red/green or yellow/blue stripes, but not their outer edges, results in the entire region being perceived simultaneously as both red/green or yellow/blue. This suggests that the percepts of reddish-green/yellowish-blue apparently are possible in corticocortical color vision…

  11. Detection of natural infection of infectious spleen and kidney necrosis virus in farmed tilapia by hydroxynapthol blue-loop-mediated isothermal amplification assay.

    PubMed

    Suebsing, R; Pradeep, P J; Jitrakorn, S; Sirithammajak, S; Kampeera, J; Turner, W A; Saksmerprome, V; Withyachumnarnkul, B; Kiatpathomchai, W

    2016-07-01

    Infectious spleen and kidney necrosis virus (ISKNV) has recently been recognized as a causative agent of serious systemic disease in tilapia. Our objective was to establish a new colorimetric loop-mediated isothermal amplification (LAMP) assay with pre-addition of hydroxynapthol blue (blue-LAMP) to investigate ISKNV transmission in tilapia. The blue-LAMP, targeting a major capsid protein gene of ISKNV, was conducted at 65°C for 45 min, allowing unaided visual detection of the pathogen based on colour change without cross-amplification of other known fish pathogens tested. Comparison of blue-LAMP and PCR assays revealed a higher detection level for blue-LAMP assay (41·33%) in a population of farmed tilapia infected with ISKNV. The investigation of ISKNV transmission pattern in farmed red tilapia using the blue-LAMP revealed a possible matroclinical form. The presence of ISKNV in the gonad samples was confirmed by in situ LAMP assay. Positive signals only appeared in ovarian follicles, and not in oocytes. Moreover, tissue tropism assay revealed that the brain was the main target organ in both farmed red tilapia (40%) and Nile tilapia (20%). The developed blue-LAMP assay has the potential to be used as a viable tool for screening covert and natural infections of ISKNV in tilapia. The evidence of vertical transmission of ISKNV infection in tilapia indicates the seriousness of this disease and will require a close attention and collaboration between tilapia hatcheries and disease experts in order to find a solution. The new blue-LAMP assay is a time-saving and economically viable detection tool, which allows unaided visual detection for ISKNV in tilapia, and it could be applicable for field applications. Evidence on the vertical transmission of ISKNV in farmed tilapia suggests a need for developing farm management practices to control the spread of virus in aquaculture industries. © 2016 The Society for Applied Microbiology.

  12. Host sphingomyelin increases West Nile virus infection in vivo

    PubMed Central

    Martín-Acebes, Miguel A.; Gabandé-Rodríguez, Enrique; García-Cabrero, Ana M.; Sánchez, Marina P.; Ledesma, María Dolores; Sobrino, Francisco; Saiz, Juan-Carlos

    2016-01-01

    Flaviviruses, such as the dengue virus and the West Nile virus (WNV), are arthropod-borne viruses that represent a global health problem. The flavivirus lifecycle is intimately connected to cellular lipids. Among the lipids co-opted by flaviviruses, we have focused on SM, an important component of cellular membranes particularly enriched in the nervous system. After infection with the neurotropic WNV, mice deficient in acid sphingomyelinase (ASM), which accumulate high levels of SM in their tissues, displayed exacerbated infection. In addition, WNV multiplication was enhanced in cells from human patients with Niemann-Pick type A, a disease caused by a deficiency of ASM activity resulting in SM accumulation. Furthermore, the addition of SM to cultured cells also increased WNV infection, whereas treatment with pharmacological inhibitors of SM synthesis reduced WNV infection. Confocal microscopy analyses confirmed the association of SM with viral replication sites within infected cells. Our results unveil that SM metabolism regulates flavivirus infection in vivo and propose SM as a suitable target for antiviral design against WNV. PMID:26764042

  13. West Nile virus and USUTU--a threat to Poland.

    PubMed

    Moniuszko-Malinowska, Anna; Czupryna, Piotr; Dunaj, Justyna; Zajkowska, Joanna; Siemieniako, Agnieszka; Pancewicz, Sławomir

    2016-01-01

    In recent years emergence of new infectious diseases and the growing spread of pathogens to new areas is observed. Most of these pathogens are zoonotic viruses and their transmission route is from animals to humans and vice versa. These so called emerging and re-emerging pathogens that were present previously only in Africa and Asia are becoming a threat to European countries. These include, e.g. West Nile virus and USUTU virus. The aim of the study is to present the clinical course of infections caused by WVN and USUTU, diagnostic and therapeutic possibilities and, above all, the current epidemiological situation of these infections in the world. We also tried to answer the question whether, there is a risk of infection with these viruses in Poland. After analyzing the available literature we venture a conclusion that in Poland there is a risk of WNV and USUTU infection. Global warming, change of socio-economic conditions, travelling greatly affect the spread of these viruses. In addition there are confirmed human cases of these diseases in countries neighboring Poland, as well as presence of both viruses and the presence of vectors (Culex pipiens sl and Culex torrentium (Diptera: Culicidae)) in our country. All these facts indicate that there is a necessity of epidemiological studies and consideration of these pathogens in the differential diagnosis of febrile illness and neuroinfection.

  14. West Nile Virus in Resident Birds from Yucatan, Mexico.

    PubMed

    Chaves, Andrea; Sotomayor-Bonilla, Jesus; Monge, Otto; Ramírez, Abigaíl; Galindo, Francisco; Sarmiento-Silva, Rosa Elena; Gutiérrez-Espeleta, Gustavo A; Suzán, Gerardo

    2016-01-01

    West Nile virus (WNV) in the Americas is thought to be transported at large spatial scales by migratory birds and locally spread and amplified by resident birds. Local processes, including interspecific interactions and dominance of passerine species recognized as competent reservoirs, may boost infection and maintain endemic cycles. Change in species composition has been recognized as an important driver for infection dynamics. Due to migration and changes in species diversity and composition in wintering grounds, changes in infection prevalence are expected. To these changes, we used PCR to estimate the prevalence of WNV in wild resident birds during the dry and rainy seasons of 2012 in Yucatan, Mexico. Serum samples were obtained from 104 wild birds, belonging to six orders and 35 species. We detected WNV in 14 resident birds, representing 11 species and three orders. Prevalences by order was Passeriformes (27%), Columbiformes (6%), and Piciformes (33%). Resident birds positive to WNV from Yucatan may be indicative of local virus circulation and evidence of past virus transmission activity.

  15. West nile virus and other arboviral diseases - United States, 2013.

    PubMed

    Lindsey, Nicole P; Lehman, Jennifer A; Staples, J Erin; Fischer, Marc

    2014-06-20

    Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes and ticks. West Nile virus (WNV) is the leading cause of domestically acquired arboviral disease in the United States. However, several other arboviruses also cause sporadic cases and seasonal outbreaks of neuroinvasive disease (i.e., meningitis, encephalitis, and acute flaccid paralysis). This report summarizes surveillance data reported to CDC in 2013 for WNV and other nationally notifiable arboviruses, excluding dengue. Forty-seven states and the District of Columbia reported 2,469 cases of WNV disease. Of these, 1,267 (51%) were classified as WNV neuroinvasive disease, for a national incidence of 0.40 per 100,000 population. After WNV, the next most commonly reported cause of arboviral disease was La Crosse virus (LACV) (85 cases), followed by Jamestown Canyon virus (JCV), Powassan virus (POWV), and eastern equine encephalitis virus (EEEV) (eight). WNV and other arboviruses continue to cause serious illness in substantial numbers of persons annually. Maintaining surveillance remains important to help direct and promote prevention activities.

  16. Clinical Sentinel Surveillance of Equine West Nile Fever, Spain.

    PubMed

    Saegerman, C; Alba-Casals, A; García-Bocanegra, I; Dal Pozzo, F; van Galen, G

    2016-04-01

    West Nile fever (WNF) is a viral zoonotic infection caused by a mosquito-borne flavivirus of the Flaviviridae family. According to a comparative study, the passive surveillance of horses by equine veterinarians appeared to be the most cost-effective system in the European context of WNF. Clinical data issued from a passive epidemiosurveillance network from September 2010 to December 2011 on horses in Spain were statistically compared and used to develop a predictive diagnostic decision tree, both with the aim to improve the early clinical detection of WNF in horses. Although clinical signs were variable in horses affected by WNF, four clinical signs and the month of occurrence were identified as useful indicators to distinguish between WNF-related and WNF-unrelated cases. The signs that pointed out a presumptive diagnosis of WNF in horses were cranial nerves deficits, limb paralysis, photophobia and nasal discharge. Clinical examination of horses with neurological signs that are not vaccinated against WNV could provide important clues for the early clinical detection of WNF and therefore serve as an alert for possible human viral infections. The study of the clinical pattern of WNF in horses is of importance to enhance awareness and better understanding and to optimize surveillance designs for clinical detection of WNF in horses in advance of epidemic activity affecting humans.

  17. Does reservoir host mortality enhance transmission of West Nile virus?

    PubMed Central

    Foppa, Ivo M; Spielman, Andrew

    2007-01-01

    Background Since its 1999 emergence in New York City, West Nile virus (WNV) has become the most important and widespread cause of mosquito-transmitted disease in North America. Its sweeping spread from the Atlantic to the Pacific coast was accompanied by widespread mortality among wild birds, especially corvids. Only sporadic avian mortality had previously been associated with this infection in the Old World. Here, we examine the possibility that reservoir host mortality may intensify transmission, both by concentrating vector mosquitoes on remaining hosts and by preventing the accumulation of "herd immunity". Results Inspection of the Ross-Macdonald expression of the basic reproductive number (R0) suggests that this quantity may increase with reservoir host mortality. Computer simulation confirms this finding and indicates that the level of virulence is positively associated with the numbers of infectious mosquitoes by the end of the epizootic. The presence of reservoir incompetent hosts in even moderate numbers largely eliminated the transmission-enhancing effect of host mortality. Local host die-off may prevent mosquitoes to "waste" infectious blood meals on immune host and may thus facilitate perpetuation and spread of transmission. Conclusion Under certain conditions, host mortality may enhance transmission of WNV and similarly maintained arboviruses and thus facilitate their emergence and spread. The validity of the assumptions upon which this argument is built need to be empirically examined. PMID:17498307

  18. Department of Defense West Nile virus surveillance in 2002.

    PubMed

    Witt, Clara Josting; Brundage, Mary; Cannon, Charles; Cox, Kenneth; Clements, Tamara E; Cooper, Edwin D; Elbert, Yevgeniy; Ludwig, George V; Mangiafico, Joseph A; Malakooti, Mark; Miller, Mellissa K; Osborn, Steve D; Pagac, Ben; Ross, Lenoir P; Shelton, Larry J; Spring, Alexandra; Kelley, Patrick

    2004-06-01

    The Department of Defense (DoD) has engaged in West Nile virus (WNV) surveillance and response since 1999. In 2002, the three Services continued their cooperative, multidisciplinary approach to the WNV outbreak. Activities included a doubling of mosquito surveillance and vector control responses, extension of and doubling of bird and nonhuman mammal surveillance to all four continental United States regions, expanded diagnostic testing by DoD laboratories, and installation environmental clean up and personnel protection campaigns. Medical treatment facilities conducted passive surveillance and reported possible cases in DoD health care beneficiaries. Efforts were coordinated through active communication within installations, with commands, and with surrounding communities. Undertaken activities complemented each other to maximize surveillance coverage. The surveillance detected WNV on 44 DoD installations. It led directly to vector control and prevention activities, and there were no confirmed cases of WNV reported in the DoD force. This multi-Service effort is a surveillance template for future outbreaks that threaten DoD force health.

  19. West Nile Virus Antibody Prevalence in Horses in Ukraine

    PubMed Central

    Ziegler, Ute; Skrypnyk, Artem; Keller, Markus; Staubach, Christoph; Bezymennyi, Maksym; Damiani, Armando M.; Osterrieder, Nikolaus; Groschup, Martin H.

    2013-01-01

    West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years ago, yet the current epidemiological status is quite unclear. In this study, serum samples from over 300 equines were collected and screened in order to detect current WNV activity in Ukraine with the goal to estimate the risk of infection for humans and horses. Sera were tested by enzyme-linked immunosorbent assay (ELISA) and virus neutralization assay (NT) to detect WNV-specific antibodies. The results clearly revealed that WNV circulates in most of the regions from which samples were obtained, shown by a WNV seroprevalence rate of 13.5% of examined horses. This is the first topical report indicating the presence of WNV infections in horses in Ukraine, and the results of this study provide evidence of a widespread WNV circulation in this country. PMID:24100889

  20. Spreading of West Nile virus infection in Croatia.

    PubMed

    Barbić, Ljubo; Listeš, Eddy; Katić, Sanda; Stevanović, Vladimir; Madić, Josip; Starešina, Vilim; Labrović, Ankica; Di Gennaro, Annapia; Savini, Giovanni

    2012-10-12

    West Nile virus (WNV) is an emerging zoonotic pathogen with rapid global expansion. The virus circulation is confirmed in many countries of Mediterranean Basin and Southern and Central Europe. In our study detection of specific WNV antibodies was performed in horses and cattle sera samples collected from October 2010 to April 2011. Serum samples were randomly taken from different parts of Croatia and tested by IgG and IgM ELISA. Positive serological results were confirmed by virus neutralization assay (VN-assay) and plaque reduction neutralization test (PRNT). Results showed that WNV antibodies were present in 72 out of 2098 horse sera (3.43%) and 3 of 2695 cattle sera (0.11%). The highest seroprevalence was found in Eastern Croatia in counties next to Hungarian, Serbian and Bosnia and Herzegovinian state borders. In Adriatic part of Croatia positive animals were found only in the westernmost county, near Slovenian and Italian borders. Geographic distribution and number of positive horses indicated that WNV is highly present in Croatia and spreading from East to West. However, positive horses in westernmost part of country indicate possible second origin of spreading. Location of serological positive cattle supports the hypothesis that seropositive cattle could be indicators of high WNV activity in the respective geographic regions.

  1. CEREBELLAR AND MESENCEPHALON NEOPLASIA IN A NILE HIPOPPOTAMUS (HIPPOPOTAMUS AMPHIBIOUS).

    PubMed

    Schiaffino, Francesca; Sander, Samantha J; Bacares, Marcia E Pereira; Barnes, Katie J; Kiupel, Matti; Walsh, Timothy; Murray, Suzan

    2016-12-01

    A 52-yr-old female Nile hippopotamus ( Hippopotamus amphibious ) was presented for acute onset anorexia, depression, lethargy, instability, and weakness in the pelvic limbs. Clinical signs were rapidly progressive, despite empiric therapy with anti-inflammatory medications, resulting in the death of the animal. Gross necropsy evaluation revealed two tan, firm masses in the cerebellum and mesencephalon and a single mass in the right cranial adrenal gland. All three masses had a similar histologic morphology, and immunohistochemical investigation confirmed the general diagnosis of an adenocarcinoma, but the exact cell of origin remains unclear. In addition, there was evidence of neuroendocrine differentiation in the adrenal gland and not in the brain. These findings suggest either two distinct neoplastic populations or a metastasizing adenocarcinoma with focal endocrine differentiation. In dogs, anal sac and clitoral adenocarcinomas have been reported to undergo focal endocrine differentiation, and both can cause widespread metastasis while the primary lesion can be small. A small neoplasm of these glands may have been missed on gross examination.

  2. West Nile Virus–infected Mosquitoes, Louisiana, 2002

    PubMed Central

    Nasci, Roger; Savage, Harry M.; Aspen, Stephen; King, Raymond; Powers, Ann M.; Burkhalter, Kristen; Colton, Leah; Charnetzky, Dawn; Lasater, Sarah; Taylor, Viki; Palmisano, Charles T.

    2005-01-01

    Human cases of West Nile virus (WNV) disease appeared in St. Tammany and Tangipahoa Parishes in southeastern Louisiana in June 2002. Cases peaked during July, then rapidly declined. We conducted mosquito collections from August 3 to August 15 at residences of patients with confirmed and suspected WNV disease to estimate species composition, relative abundance, and WNV infection rates. A total of 31,215 mosquitoes representing 25 species were collected by using primarily gravid traps and CO2-baited light traps. Mosquitoes containing WNV RNA were obtained from 5 of 11 confirmed case sites and from 1 of 3 sites with non-WNV disease. WNV RNA was detected in 9 mosquito pools, including 7 Culex quinquefasciatus, 1 Cx. salinarius, and 1 Coquillettidia perturbans. Mosquito infection rates among sites ranged from 0.8/1,000 to 10.9/1,000. Results suggest that Cx. quinquefasciatus was the primary epizootic/epidemic vector, with other species possibly playing a secondary role. PMID:16229769

  3. Economic Conditions Predict Prevalence of West Nile Virus

    PubMed Central

    Buermann, Wolfgang; Cummings, Robert F.; Kahn, Matthew E.; Smith, Thomas B.

    2010-01-01

    Understanding the conditions underlying the proliferation of infectious diseases is crucial for mitigating future outbreaks. Since its arrival in North America in 1999, West Nile virus (WNV) has led to population-wide declines of bird species, morbidity and mortality of humans, and expenditures of millions of dollars on treatment and control. To understand the environmental conditions that best explain and predict WNV prevalence, we employed recently developed spatial modeling techniques in a recognized WNV hotspot, Orange County, California. Our models explained 85–95% of the variation of WNV prevalence in mosquito vectors, and WNV presence in secondary human hosts. Prevalence in both vectors and humans was best explained by economic variables, specifically per capita income, and by anthropogenic characteristics of the environment, particularly human population and neglected swimming pool density. While previous studies have shown associations between anthropogenic change and pathogen presence, results show that poorer economic conditions may act as a direct surrogate for environmental characteristics related to WNV prevalence. Low-income areas may be associated with higher prevalence for a number of reasons, including variations in property upkeep, microhabitat conditions conducive to viral amplification in both vectors and hosts, host community composition, and human behavioral responses related to differences in education or political participation. Results emphasize the importance and utility of including economic variables in mapping spatial risk assessments of disease. PMID:21103053

  4. Economic conditions predict prevalence of West Nile virus.

    PubMed

    Harrigan, Ryan J; Thomassen, Henri A; Buermann, Wolfgang; Cummings, Robert F; Kahn, Matthew E; Smith, Thomas B

    2010-11-12

    Understanding the conditions underlying the proliferation of infectious diseases is crucial for mitigating future outbreaks. Since its arrival in North America in 1999, West Nile virus (WNV) has led to population-wide declines of bird species, morbidity and mortality of humans, and expenditures of millions of dollars on treatment and control. To understand the environmental conditions that best explain and predict WNV prevalence, we employed recently developed spatial modeling techniques in a recognized WNV hotspot, Orange County, California. Our models explained 85-95% of the variation of WNV prevalence in mosquito vectors, and WNV presence in secondary human hosts. Prevalence in both vectors and humans was best explained by economic variables, specifically per capita income, and by anthropogenic characteristics of the environment, particularly human population and neglected swimming pool density. While previous studies have shown associations between anthropogenic change and pathogen presence, results show that poorer economic conditions may act as a direct surrogate for environmental characteristics related to WNV prevalence. Low-income areas may be associated with higher prevalence for a number of reasons, including variations in property upkeep, microhabitat conditions conducive to viral amplification in both vectors and hosts, host community composition, and human behavioral responses related to differences in education or political participation. Results emphasize the importance and utility of including economic variables in mapping spatial risk assessments of disease.

  5. Hydroclimatic Assessment of West Nile Virus Occurrence Across Continental US

    NASA Astrophysics Data System (ADS)

    Billian, H. E.; Jutla, A.; Colwell, R. R.

    2014-12-01

    West Nile virus (WNV) is the most widely infections from arbovirus in mid-latitudes, having reached the Western Hemisphere in 1999. As a vector-borne disease, WNV is primarily spread by mosquitoes; the disease is predominantly found in tropical and temperate regions of the world, and is now considered an endemic pathogen in the United States, Africa, Asia, Australia, the Middle East, and Europe. Environmental processes play a vital role in the trigger of WNV. Here, using logistical regression models, we quantified relationships between hydroclimatic processes and mosquito abundance for WNV across the continental USA using precipitation and temperature at different spatial and temporal scales. It will be shown that reported cases of this disease are more prevalent during spring and summer months in the entire country, when there is more precipitation and higher surface air temperatures for 2003 to 2013. The key impacts of this research are those related to the improvement of human health, and a means to predict mosquito breeding patterns long term as they relate to the prevalence of vector-borne illnesses.

  6. West Nile virus: A re-emerging pathogen revisited

    PubMed Central

    Martín-Acebes, Miguel A; Saiz, Juan-Carlos

    2012-01-01

    West Nile virus (WNV), a flavivirus of the Flaviviridae family, is maintained in nature in an enzootic transmission cycle between avian hosts and ornithophilic mosquito vectors, although the virus occasionally infects other vertebrates. WNV causes sporadic disease outbreaks in horses and humans, which may result in febrile illness, meningitis, encephalitis and flaccid paralysis. Until recently, its medical and veterinary health concern was relatively low; however, the number, frequency and severity of outbreaks with neurological consequences in humans and horses have lately increased in Europe and the Mediterranean basin. Since its introduction in the Americas, the virus spread across the continent with worrisome consequences in bird mortality and a considerable number of outbreaks among humans and horses, which have resulted in the largest epidemics of neuroinvasive WNV disease ever documented. Surprisingly, its incidence in human and animal health is very different in Central and South America, and the reasons for it are not yet understood. Even though great advances have been obtained lately regarding WNV infection, and although efficient equine vaccines are available, no specific treatments or vaccines for human use are on the market. This review updates the most recent investigations in different aspects of WNV life cycle: molecular virology, transmission dynamics, host range, clinical presentations, epidemiology, ecology, diagnosis, control, and prevention, and highlights some aspects that certainly require further research. PMID:24175211

  7. West Nile Virus Outbreak in North American Owls, Ontario, 2002

    PubMed Central

    Barker, Ian K.; Lindsay, Robbin; Dibernardo, Antonia; McKeever, Katherine; Hunter, Bruce

    2004-01-01

    From July to September 2002, an outbreak of West Nile virus (WNV) caused a high number of deaths in captive owls at the Owl Foundation, Vineland, Ontario, Canada. Peak death rates occurred in mid-August, and the epidemiologic curve resembled that of corvids in the surrounding Niagara region. The outbreak occurred in the midst of a louse fly (Icosta americana, family Hippoboscidae) infestation. Of the flies tested, 16 (88.9 %) of 18 contained WNV RNA. Species with northern native breeding range and birds >1 year of age were at significantly higher risk for WNV-related deaths. Species with northern native breeding range and of medium-to-large body size were at significantly higher risk for exposure to WNV. Taxonomic relations (at the subfamily level) did not significantly affect exposure to WNV or WNV-related deaths. Northern native breeding range and medium-to-large body size were associated with earlier death within the outbreak period. Of the survivors, 69 (75.8 %) of 91 were seropositive for WNV. PMID:15663850

  8. Factors associated with West Nile virus disease fatalities in horses.

    PubMed

    Epp, Tasha; Waldner, Cheryl; West, Keith; Townsend, Hugh

    2007-11-01

    In 2003, the occurrence and location of horses with clinical signs of West Nile virus infection were identified in the southern portion of Saskatchewan with the help of veterinarians, owners, and the regional laboratory. A total of 133 clinical cases were reported between July 30 and September 19, 2003; however, postseason surveillance suggests that the number of cases was underestimated. The case fatality rate was 43.8% (95% CI 35.2, 52.4). Factors associated with fatality in clinical cases included sex, week of onset of clinical signs, and coat color. Reported clinical cases clustered within regional health authority districts, suggesting regional differences in geographic factors, potentially including climate and mosquito control, that could contribute to the risk of disease. However, most of the variation in the risk of fatality in clinical cases is explained at the individual level rather than the Regional Health Authority level, which suggests the outcome of clinical disease is primarily determined by characteristics of, or management factors affecting, the individual horse.

  9. IL-22 signaling contributes to West Nile encephalitis pathogenesis.

    PubMed

    Wang, Penghua; Bai, Fengwei; Zenewicz, Lauren A; Dai, Jianfeng; Gate, David; Cheng, Gong; Yang, Long; Qian, Feng; Yuan, Xiaoling; Montgomery, Ruth R; Flavell, Richard A; Town, Terrence; Fikrig, Erol

    2012-01-01

    The Th17 cytokine, IL-22, regulates host immune responses to extracellular pathogens. Whether IL-22 plays a role in viral infection, however, is poorly understood. We report here that Il22(-/-) mice were more resistant to lethal West Nile virus (WNV) encephalitis, but had similar viral loads in the periphery compared to wild type (WT) mice. Viral loads, leukocyte infiltrates, proinflammatory cytokines and apoptotic cells in the central nervous system (CNS) of Il22(-/-) mice were also strikingly reduced. Further examination showed that Cxcr2, a chemokine receptor that plays a non-redundant role in mediating neutrophil migration, was significantly reduced in Il22(-/-) compared to WT leukocytes. Expression of Cxcr2 ligands, cxcl1 and cxcl5, was lower in Il22(-/-) brains than wild type mice. Correspondingly, neutrophil migration from the blood into the brain was attenuated following lethal WNV infection of Il22(-/-) mice. Our results suggest that IL-22 signaling exacerbates lethal WNV encephalitis likely by promoting WNV neuroinvasion.

  10. Extinction of West Nile virus by Favipiravir through lethal mutagenesis.

    PubMed

    Escribano-Romero, Estela; Jiménez de Oya, Nereida; Domingo, Esteban; Saiz, Juan Carlos

    2017-08-28

    Favipiravir is an antiviral agent effective against several RNA viruses. The drug has been shown to protect mice against experimental infection with a lethal dose of West Nile virus (WNV), a mosquito-borne flavivirus responsible for outbreaks of meningitis and encephalitis for which no antiviral therapy has been licensed; however, the mechanism of action of the drug is still not well understood. Here, we describe the potent in vitro antiviral activity of favipiravir against WNV, showing that it decreases the virus-specific infectivity and drives the virus to extinction. Two passages of WNV in the presence of 1mM favipiravir -a concentration which is more than 10-fold lower than its cytotoxic concentration 50 (CC50)- resulted in a significant increase of mutation frequency in the mutant spectrum, and in a bias towards A-to-G and G-to-A transitions relative to the population passaged in absence of the drug. These data, together with the fact that the drug is already licensed in Japan against influenza virus and in clinical trial against Ebola virus, point to favipiravir as a promising antiviral agent to fight medically relevant flaviviral infections, such as that caused by WNV. Copyright © 2017 American Society for Microbiology.

  11. Effects of detergents on the West Nile virus protease activity.

    PubMed

    Ezgimen, Manolya D; Mueller, Niklaus H; Teramoto, Tadahisa; Padmanabhan, R

    2009-05-01

    Detergents such as Triton X-100 are often used in drug discovery research to weed out small molecule promiscuous and non-specific inhibitors which act by aggregation in solution and undesirable precipitation in aqueous assay buffers. We evaluated the effects of commonly used detergents, Triton X-100, Tween-20, Nonidet-40 (NP-40), Brij-35, and CHAPS, on the enzymatic activity of West Nile virus (WNV) protease. Unexpectedly, Triton X-100, Tween-20, and NP-40 showed an enhancement of in vitro WNV protease activity from 2 to 2.5-fold depending on the detergent and its concentration. On the other hand, Brij-35, at 0.001% enhanced the protease activity by 1.5-fold and CHAPS had the least enhancing effect. The kinetic analysis showed that the increase in protease activity by Triton X-100 was dose-dependent. Furthermore, at Triton X-100 and Tween-20 concentrations higher than 0.001%, the inhibition of compound B, one of the lead compounds against WNV protease identified in a high throughput screen (IC(50) value of 5.7+/-2.5 microM), was reversed. However, in the presence of CHAPS, compound B still showed good inhibition of WNV protease. Our results, taken together, indicate that nonionic detergents, Triton X-100, Tween, and NP-40 are unsuitable for the purpose of discrimination of true versus promiscuous inhibitors of WNV protease in high throughput assays.

  12. The fluvial evolution of the Holocene Nile Delta

    NASA Astrophysics Data System (ADS)

    Pennington, B. T.; Sturt, F.; Wilson, P.; Rowland, J.; Brown, A. G.

    2017-08-01

    The evolution of the Nile Delta, the largest delta system in the Mediterranean Sea, has both high palaeoenvironmental and archaeological significance. A dynamic model of the landscape evolution of this delta system is presented for the period c.8000-4500 cal BP. Analysis of sedimentary data and chronostratigraphic information contained within 1640 borehole records has allowed for a redefinition of the internal stratigraphy of the Holocene delta, and the construction of a four-dimensional landscape model for the delta's evolution through time. The mid-Holocene environmental evolution is characterised by a transition from an earlier set of spatially varied landscapes dominated by swampy marshland, to better-drained, more uniform floodplain environments. Archaeologically important Pleistocene inliers in the form of sandy hills protruding above the delta plain surface (known as ;turtlebacks;), also became smaller as the delta plain continued to aggrade, while the shoreline and coastal zone prograded north. These changes were forced by a decrease in the rate of relative sea-level rise under high rates of sediment-supply. This dynamic environmental evolution needs to be integrated within any discussion of the contemporary developments in the social sphere, which culminated in the emergence of the Ancient Egyptian State c.5050 cal BP.

  13. A Brief Review of West Nile Virus Biology.

    PubMed

    Londono-Renteria, Berlin; Colpitts, Tonya M

    2016-01-01

    West Nile virus (WNV) is an arbovirus with increased global incidence in the last decade. It is also a major cause of human encephalitis in the USA. WNV is an arthropod-transmitted virus that mainly affects birds but humans become infected as incidental dead-end hosts which can cause outbreaks in naïve populations. The main vectors of WNV are mosquitoes of the genus Culex, which preferentially feed on birds. As in many other arboviruses, the characteristics that allow Flaviviruses like WNV to replicate and transmit to different hosts are encrypted in their genome, which also contains information for the production of structural and nonstructural proteins needed for host cell infection. WNV and other Flaviviruses have developed different strategies to establish infection, replication, and successful transmission. Most of these strategies include the diversion of the host's immune responses away from the virus. In this review, we describe the molecular structure and protein function of WNV with emphasis on protein involvement in the modulation of antiviral immune responses.

  14. Host sphingomyelin increases West Nile virus infection in vivo.

    PubMed

    Martín-Acebes, Miguel A; Gabandé-Rodríguez, Enrique; García-Cabrero, Ana M; Sánchez, Marina P; Ledesma, María Dolores; Sobrino, Francisco; Saiz, Juan-Carlos

    2016-03-01

    Flaviviruses, such as the dengue virus and the West Nile virus (WNV), are arthropod-borne viruses that represent a global health problem. The flavivirus lifecycle is intimately connected to cellular lipids. Among the lipids co-opted by flaviviruses, we have focused on SM, an important component of cellular membranes particularly enriched in the nervous system. After infection with the neurotropic WNV, mice deficient in acid sphingomyelinase (ASM), which accumulate high levels of SM in their tissues, displayed exacerbated infection. In addition, WNV multiplication was enhanced in cells from human patients with Niemann-Pick type A, a disease caused by a deficiency of ASM activity resulting in SM accumulation. Furthermore, the addition of SM to cultured cells also increased WNV infection, whereas treatment with pharmacological inhibitors of SM synthesis reduced WNV infection. Confocal microscopy analyses confirmed the association of SM with viral replication sites within infected cells. Our results unveil that SM metabolism regulates flavivirus infection in vivo and propose SM as a suitable target for antiviral design against WNV. Copyright © 2016 by the American Society for Biochemistry and Molecular Biology, Inc.

  15. West Nile Virus in Mosquitoes of Iranian Wetlands.

    PubMed

    Bagheri, Masoomeh; Terenius, Olle; Oshaghi, Mohammad Ali; Motazakker, Morteza; Asgari, Sassan; Dabiri, Farrokh; Vatandoost, Hassan; Mohammadi Bavani, Mulood; Chavshin, Ali Reza

    2015-12-01

    The West Nile virus (WNV) transmission cycle includes a wide range of migratory wetland birds as reservoirs, mosquitoes as biological vectors, and equines and humans as dead-end hosts. Despite the presence of potential vector species, there is no information about the existence of WNV in mosquito vectors in Iran. The Iranian West Azerbaijan Province is located in the northwestern part of Iran and has borders with Turkey, Iraq, Armenia, and the Republic of Azerbaijan. The current study was conducted to identify the wetland mosquitoes of the West Azerbaijan Province and their infection with WNV. In this study, 2143 specimens were collected, comprising 1541 adults and 602 larvae. Six species belonging to four genera were collected and identified: Anopheles maculipennis sensu lato (s.l.), Culex (Cx.) hortensis, Cx. pipiens s.l., Cx. theileri, Culiseta longiareolata, and Aedes (Ae.) (Ochlerotatus) caspius. In total, 45 pools of mosquitoes were examined. Two of the adult pools collected from the same location showed the presence of WNV in Ae. (Och.) caspius, from Sangar, Makoo County, as confirmed by PCR and sequencing. Due to the discovery of WNV in the mosquito population of the region, and the presence of wetlands and significant populations of migratory birds, the health sector should carefully monitor the factors involved in the cycle of this disease.

  16. Differential virulence and pathogenesis of West Nile viruses.

    PubMed

    Donadieu, Emilie; Bahuon, Céline; Lowenski, Steeve; Zientara, Stéphan; Coulpier, Muriel; Lecollinet, Sylvie

    2013-11-22

    West Nile virus (WNV) is a neurotropic flavivirus that cycles between mosquitoes and birds but that can also infect humans, horses, and other vertebrate animals. In most humans, WNV infection remains subclinical. However, 20%-40% of those infected may develop WNV disease, with symptoms ranging from fever to meningoencephalitis. A large variety of WNV strains have been described worldwide. Based on their genetic differences, they have been classified into eight lineages; the pathogenic strains belong to lineages 1 and 2. Ten years ago, Beasley et al. (2002) found that dramatic differences exist in the virulence and neuroinvasion properties of lineage 1 and lineage 2 WNV strains. Further insights on how WNV interacts with its hosts have recently been gained; the virus acts either at the periphery or on the central nervous system (CNS), and these observed differences could help explain the differential virulence and neurovirulence of WNV strains. This review aims to summarize the current state of knowledge on factors that trigger WNV dissemination and CNS invasion as well as on the inflammatory response and CNS damage induced by WNV. Moreover, we will discuss how WNV strains differentially interact with the innate immune system and CNS cells, thus influencing WNV pathogenesis.

  17. Experimental infection of cats and dogs with West Nile virus.

    PubMed

    Austgen, Laura E; Bowen, Richard A; Bunning, Michel L; Davis, Brent S; Mitchell, Carl J; Chang, Gwong-Jen J

    2004-01-01

    Domestic dogs and cats were infected by mosquito bite and evaluated as hosts for West Nile virus (WNV). Viremia of low magnitude and short duration developed in four dogs but they did not display signs of disease. Four cats became viremic, with peak titers ranging from 10(3.0) to 10(4.0) PFU/mL. Three of the cats showed mild, non-neurologic signs of disease. WNV was not isolated from saliva of either dogs or cats during the period of viremia. An additional group of four cats were exposed to WNV orally, through ingestion of infected mice. Two cats consumed an infected mouse on three consecutive days, and two cats ate a single infected mouse. Viremia developed in all of these cats with a magnitude and duration similar to that seen in cats infected by mosquito bite, but none of the four showed clinical signs. These results suggest that dogs and cats are readily infected by WNV. The high efficiency of oral transmission observed with cats suggests that infected prey animals may serve as an important source of infection to carnivores. Neither species is likely to function as an epidemiologically important amplifying host, although the peak viremia observed in cats may be high enough to infect mosquitoes at low efficiency.

  18. Avian mortality surveillance for West Nile virus in Colorado.

    PubMed

    Nemeth, Nicole M; Beckett, Susan; Edwards, Eric; Klenk, Kaci; Komar, Nicholas

    2007-03-01

    We tested 1,549 avian carcasses of 104 species to identify targets for West Nile virus (WNV) surveillance in Colorado, determine species affected by WNV, compare virus isolation versus RNA detection applied to hearts and oral swabs from carcasses, and compare the VecTest WNV Antigen Assay (VecTest) to standard assays. Forty-two species tested positive. From June to September 2003, 86% of corvids, 34% of non-corvid passerines, and 37% of raptors tested positive. We developed the Target Species Index, which identified American crows as the most important avian indicator species. However, testing multiple species maximizes detection, which may be important early and late in the transmission season. This index may benefit surveillance for other zoonotic pathogens, such as highly pathogenic avian influenza H5N1 virus. VecTest using oral swabs was most sensitive for American crow, black-billed magpie, house finch, house sparrow, and American kestrel. Wildlife rehabilitation centers should be recruited to enhance WNV surveillance.

  19. Eyewitness introduction to Egypt: "The gift of the Nile".

    PubMed

    Brown, Geraldine

    2009-01-01

    Northeastern corner of Africa, lying at the crossroads between the two continents of Europe and Asia (in the Sinai Peninsula), while bordering Libya, Sudan, Israel and the Red Sea. Egypt is the most ancient tourist country in the world. Several health fact-finding missions in the last few years were made to this small country that is frequently defined by the Valley of the Nile. With the spreading deserts on either side, or a very rich heritage of ancient relics, these scenic vistas are without equal elsewhere in the world. Although there are significant cultural differences among the population, Egypt has a long history of ethnic and religious compassion. Among the many rarities, main tourist attractions include the three great Pyramids of Giza and the Sphinx, amazing ancient wonders of the world. These fact-finding missions included how health and medical care are defined, how people and culture are intertwined with its physical features, land use, and the economy and its resources.

  20. West Nile Virus lineage-2 in Culex specimens from Iran.

    PubMed

    Shahhosseini, Nariman; Chinikar, Sadegh; Moosa-Kazemi, Seyed Hassan; Sedaghat, Mohammad Mehdi; Kayedi, Mohammad Hassan; Lühken, Renke; Schmidt-Chanasit, Jonas

    2017-10-01

    Screening of mosquitoes for viruses is an important forecasting tool for emerging and re-emerging arboviruses. Iran has been known to harbour medically important arboviruses such as West Nile virus (WNV) and dengue virus (DENV) based on seroepidemiological data. However, there are no data about the potential mosquito vectors for arboviruses in Iran. This study was performed to provide mosquito and arbovirus data from Iran. A total of 32 317 mosquitos were collected at 16 sites in five provinces of Iran in 2015 and 2016. RT-PCR for detection of flaviviruses was performed. The PCR amplicons were sequenced, and 109 WNV sequences, including one obtained in this study, were used for phylogenetic analyses. The 32 317 mosquito specimens belonging to 25 species were morphologically distinguished and distributed into 1222 pools. Culex pipiens s.l. comprised 56.429%. One mosquito pool (0.08%), containing 46 unfed Cx. pipiens pipiens form pipiens (Cpp) captured in August 2015, was positive for flavivirus RNA. Subsequent sequencing and phylogenetic analyses revealed that the detected Iranian WNV strain belongs to lineage 2 and clusters with a strain recently detected in humans. No flaviviruses other than WNV were detected in the mosquito pools. Cpp could be a vector for WNV in Iran. Our findings indicate recent circulation of WNV lineage-2 strain in Iran and provide a solid base for more targeted arbovirus surveillance programs. © 2017 John Wiley & Sons Ltd.