US statutes for enforcement by security inspectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cadwell, J.J.; Ruger, C.J.

1995-12-01

This document is one of a three volume set. BNL 52201 is titled `Selected Text of Atomic Energy Act Executive Orders and Other Laws of General Interest to Safeguards and Security Executives`, and it contains detailed information for use by executives. BNL 52202 is titled `U.S. Statutes of General Interest to Safeguards and Security Officers`, and contains less detail than BNL 52201. It is intended for use by officers. BNL 52203 is titled `U.S. Statutes for Enforcement by Security Inspectors`, and it contains statutes to be applied by uniformed security inspectors.

Genetic analysis of fibroblast growth factor signaling in the Drosophila eye.

PubMed

Mukherjee, T; Choi, I; Banerjee, Utpal

2012-01-01

The development of eyes in Drosophila involves intricate epithelial reorganization events for accurate positioning of cells and proper formation and organization of ommatidial clusters. We demonstrate that Branchless (Bnl), the fibroblast growth factor ligand, regulates restructuring events in the eye disc primordium from as early as the emergence of clusters from a morphogenetic front to the cellular movements during pupal eye development. Breathless (Btl) functions as the fibroblast growth factor receptor to mediate Bnl signal, and together they regulate expression of DE-cadherin, Crumbs, and Actin. In addition, in the eye Bnl regulates the temporal onset and extent of retinal basal glial cell migration by activating Btl in the glia. We hypothesized that the Bnl functions in the eye are Hedgehog dependent and represent novel aspects of Bnl signaling not explored previously.

Electromyographic analysis of three different types of lat pull-down.

PubMed

Sperandei, Sandro; Barros, Marcos A P; Silveira-Júnior, Paulo C S; Oliveira, Carlos G

2009-10-01

The purpose of this work was to evaluate the activity of the primary motor muscles during the performance of 3 lat pull-down techniques through surface electromyography (EMG). Twenty-four trained adult men performed 5 repetitions of behind-the-neck (BNL), front-of-the-neck (FNL), and V-bar exercises at 80% of 1 repetition maximum. For each technique, the root mean square from the EMG signal was registered from the pectoralis major (PM), latissimus dorsi (LD), posterior deltoid (PD), and biceps brachii (BB) and further normalized in respect to that which presented the highest value of all the techniques. A series of two-way repeated measures analysis of variance was used to compare the results, with Tukey-Kramer as the post hoc test and alpha = 0.05. During the concentric phase, PM value showed the FNL to be significantly higher than V-bar/BNL and V-bar higher than BNL. During the eccentric phase, FNL/V-bar was higher than BNL. For LD, there was no difference between techniques. PD presented BNL higher than FNL/V-bar and FNL higher than V-bar in the concentric phase and BNL higher than V-bar in the eccentric phase. BB exhibited BNL higher than V-bar/FNL and V-bar higher than FNL in both concentric and eccentric phases. Considering the main objectives of lat pull-down, we concluded that FNL is the better choice, whereas BNL is not a good lat pull-down technique and should be avoided. V-bar could be used as an alternative.

Divergent Pseudomonas exotoxin A sensitivity in normal and transformed liver cells is correlated with low-density lipoprotein receptor-related protein expression.

PubMed

Laithwaite, J E; Benn, S J; Marshall, W S; FitzGerald, D J; LaMarre, J

2001-09-01

Pseudomonas exotoxin A (PEA) is an extracellular virulence factor produced by the opportunistic human pathogen Pseudomonas aerguinosa. PEA intoxification begins when PEA binds to the low-density lipoprotein receptor-related protein (LRP). The liver is the primary target of systemic PEA, due largely to the high levels of functional LRP expressed by liver cells. Using a 3H-leucine incorporation assay to measure inhibition of protein synthesis we have demonstrated that normal (BNL CL.2) and transformed (BNL 1ME A7R.1) liver cells exhibit divergent PEA sensitivity; with BNL 1ME A7R.1 cells demonstrating greater PEA sensitivity than their non-transformed counterparts. The receptor-associated protein, a LRP antagonist, decreased PEA toxicity in BNL 1ME A7R.1 cells, confirming the importance of the LRP in PEA intoxification in this cell type. Increased PEA sensitivity in BNL 1ME A7R.1 cells was associated with increased functional cell surface LRP expression, as measured by alpha2-macroglobulin binding and internalization studies, and increased LRP mRNA levels, as determined by Northern blot analysis. Interestingly, BNL CL.2 cells were more sensitive than BNL 1ME A7R.1 cells to conjugate and mutant PEA toxins that do not utilize the LRP for cellular entry. These data demonstrate that increased LRP expression is an important mechanism by which PEA sensitivity is increased in BNL 1ME A7R.1 transformed liver cells.

Effects of tocotrienols on cell viability and apoptosis in normal murine liver cells (BNL CL.2) and liver cancer cells (BNL 1ME A.7R.1), in vitro.

PubMed

Har, Chan Hooi; Keong, Chan Kok

2005-01-01

The effects of tocotrienols on murine liver cell viability and their apoptotic events were studied over a dose range of 0-32 microg mL(-1). Normal murine liver cells (BNL CL.2) and murine liver cancer cells (BNL 1ME A.7R.1) were treated with tocotrienols (T(3)), alpha tocopherol (alpha-T) and the chemo drug, Doxorubicin (Doxo, as a positive control). Cell viability assay showed that T(3) significantly (P < or = 0.05) lowered the percentage of BNL 1ME A.7R.1 cell viability in a dose-responsive manner (8-16 microg mL(-1)), whereas T did not show any significant (P>0.05) inhibition in cell viability with increasing treatment doses of 0-16 microg mL(-1). The IC(50) for tocotrienols were 9.8, 8.9, 8.1, 9.7, 8.1 and 9.3 microg mL(-1) at 12, 24, 36, 48, 60 and 72 hours respectively. Early apoptosis was detected 6 hours following T(3) treatment of BNL 1ME A.7R.1 liver cancer cells, using Annexin V-FITC fluorescence microscopy assay for apoptosis, but none were observed for the non-treated liver cancer cells at the average IC(50) of 8.98 microg mL(-1) tocotrienols for liver cancer cells. Several apoptotic bodies were detected in BNL 1ME A.7R.1 liver cancer cells at 6 hours post-treatment with tocotrienols (8.98 microg mL(-1)) using Acridine Orange/Propidium Iodide fluorescence assay. However, only a couple of apoptotic bodies were seen in the non-treated liver cancer cells and the BNL CL.2 normal liver cells. Some mitotic bodies were also observed in the T(3)-treated BNL 1ME A.7R.1 liver cancer cells but were not seen in the untreated BNL 1ME A.7R.1 cells and the BNL CL.2 liver cells. Following T(3)-treatment (8.98 microg mL(-1)) of the BNL 1ME A.7R.1 liver cancer cells, 24.62%, 25.53% and 44.90% of the cells showed elevated active caspase 3 activity at 9, 12 and 24 hours treatment period, respectively. DNA laddering studies indicated DNA fragmentation occurred in the T(3)-treated liver cancer cells, BNL 1ME A.7R.1 but not in non-treated liver cancer cells and the T(3)-treated and non-treated normal liver cells. These results suggest that tocotrienols were able to reduce the cell viability in the murine liver cancer cells at a dose of 8-32 microg mL(-1) and that this decrease in percentage cell viability may be due to apoptosis.

Rhodiola sachalinesis induces the expression of inducible nitric oxide synthase gene by murine fetal hepatocytes (BNL CL.2).

PubMed

Pae, H O; Seo, W G; Oh, G S; Kim, N Y; Kim, Y M; Kwon, T O; Shin, M K; Chai, K Y; Chung, H T

2001-02-01

We have examined the effect of the aqueous extract of Rhodiola sachalinensis root (RSE), a traditional herbal medicine, on nitric oxide (NO) synthesis in murine fetal hepatocytes (BNL CL.2) by measuring the stable end-product nitrite and the mRNA of inducible NO synthase (iNOS). Interferon-gamma (IFN-gamma) by itself failed to induce NO synthesis in BNL CL.2 cells. RSE also did not elicit NO synthesis at concentrations up to 1,000 microg/ml, but dose- and time-dependently induced NO synthesis in the presence of IFN-gamma in BNL CL.2 cells. Whereas RSE or IFN-gamma failed to induce detectable levels of iNOS mRNA, a combination of RSE and IFN-gamma markedly induced iNOS mRNA in BNL CL.2 cells. Thus, we found that RSE triggered IFN-gamma-primed BNL CL.2 cells to synthesize NO by inducing iNOS gene expression. The capability of RSE to induce NO synthesis might be related to the therapeutic efficacy of RSE on the liver diseases.

Genetic Analysis of Fibroblast Growth Factor Signaling in the Drosophila Eye

PubMed Central

Mukherjee, T.; Choi, I.; Banerjee, Utpal

2012-01-01

The development of eyes in Drosophila involves intricate epithelial reorganization events for accurate positioning of cells and proper formation and organization of ommatidial clusters. We demonstrate that Branchless (Bnl), the fibroblast growth factor ligand, regulates restructuring events in the eye disc primordium from as early as the emergence of clusters from a morphogenetic front to the cellular movements during pupal eye development. Breathless (Btl) functions as the fibroblast growth factor receptor to mediate Bnl signal, and together they regulate expression of DE-cadherin, Crumbs, and Actin. In addition, in the eye Bnl regulates the temporal onset and extent of retinal basal glial cell migration by activating Btl in the glia. We hypothesized that the Bnl functions in the eye are Hedgehog dependent and represent novel aspects of Bnl signaling not explored previously. PMID:22384378

Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways

PubMed Central

Ogunwobi, Olorunseun O.

2013-01-01

Advanced hepatocellular carcinoma (HCC) is an important cause of cancer mortality. Epithelial-mesenchymal transition (EMT) has been shown to be an important biological process in cancer progression and metastasis. We have focused on elucidating factors that induce EMT to promote carcinogenesis and subsequent metastasis in HCC using the BNL CL.2 (BNL) and BNL 1ME A. 7R.1 (1MEA) cell lines. BNL cells are normal hepatocytes whereas the 1MEA cells are HCC cells derived from chemical transformation of the BNL cells. Their morphological characteristics were examined. Expression levels of hepatocyte growth factor (HGF), markers of EMT and mediators of HGF signaling were determined and functional characteristics were compared. BNL cells were treated with HGF and effects on EMT-marker and mediators of HGF signaling were analyzed. BNL cells display characteristic epithelial morphology whereas 1MEA cells display mesenchymal characteristics. 1MEA cells express and secrete more HGF than BNL cells. There was significantly decreased expression of E-cadherin, albumin, AAT and increased expression of fibronectin, collagen-1, vimentin, snail and slug in 1MEA cells. There was also increased expression of cyclooxygenase-2 (COX-2), Akt and phosphorylated Akt (pAkt) in 1MEA cells. Moreover, 1MEA cells had increased migratory capacity inhibited by inhibition of COX-2 and Akt but not extracellular signal regulated kinase (ERK). Molecular mesenchymal characteristics of 1MEA cells were reversed by inhibition of COX-2, Akt and ERK. Treatment of BNL cells with HGF led to decreased expression of E-cadherin and increased expression of fibronectin, vimentin, snail, slug, COX-2, Akt, pAkt and increased migration, invasiveness and clonogenicity. We conclude that development of HCC is associated with upregulation of HGF which promotes EMT and carcinogenesis via upregulation of COX-2 and Akt. Consequently, HGF signaling may be targeted for therapy in advanced and metastatic HCC. PMID:21744257

Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways.

PubMed

Ogunwobi, Olorunseun O; Liu, Chen

2011-12-01

Advanced hepatocellular carcinoma (HCC) is an important cause of cancer mortality. Epithelial-mesenchymal transition (EMT) has been shown to be an important biological process in cancer progression and metastasis. We have focused on elucidating factors that induce EMT to promote carcinogenesis and subsequent metastasis in HCC using the BNL CL.2 (BNL) and BNL 1ME A. 7R.1 (1MEA) cell lines. BNL cells are normal hepatocytes whereas the 1MEA cells are HCC cells derived from chemical transformation of the BNL cells. Their morphological characteristics were examined. Expression levels of hepatocyte growth factor (HGF), markers of EMT and mediators of HGF signaling were determined and functional characteristics were compared. BNL cells were treated with HGF and effects on EMT-marker and mediators of HGF signaling were analyzed. BNL cells display characteristic epithelial morphology whereas 1MEA cells display mesenchymal characteristics. 1MEA cells express and secrete more HGF than BNL cells. There was significantly decreased expression of E-cadherin, albumin, AAT and increased expression of fibronectin, collagen-1, vimentin, snail and slug in 1MEA cells. There was also increased expression of cyclooxygenase-2 (COX-2), Akt and phosphorylated Akt (pAkt) in 1MEA cells. Moreover, 1MEA cells had increased migratory capacity inhibited by inhibition of COX-2 and Akt but not extracellular signal regulated kinase (ERK). Molecular mesenchymal characteristics of 1MEA cells were reversed by inhibition of COX-2, Akt and ERK. Treatment of BNL cells with HGF led to decreased expression of E-cadherin and increased expression of fibronectin, vimentin, snail, slug, COX-2, Akt, pAkt and increased migration, invasiveness and clonogenicity. We conclude that development of HCC is associated with upregulation of HGF which promotes EMT and carcinogenesis via upregulation of COX-2 and Akt. Consequently, HGF signaling may be targeted for therapy in advanced and metastatic HCC.

Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion sourcea)

NASA Astrophysics Data System (ADS)

Kondo, K.; Yamamoto, T.; Sekine, M.; Okamura, M.

2012-02-01

The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (˜100 μA) with high charge (˜10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline.

Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion source.

PubMed

Kondo, K; Yamamoto, T; Sekine, M; Okamura, M

2012-02-01

The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (∼100 μA) with high charge (∼10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline.

Gene transfer to liver cancer cells of B7-1 plus interleukin 12 changes immunoeffector mechanisms and suppresses helper T cell type 1 cytokine production induced by interleukin 12 alone.

PubMed

Sun, Y; Qian, C; Peng, D; Prieto, J

2000-01-01

To investigate the cooperative effect of B7-1 and IL-12 in the induction of antitumor activity, we have developed retroviral vectors encoding human B7-1, murine IL-12, or both B7-1 and IL-12 coordinately. Murine transformed liver cells (BNL) were engineered to stably express B7-1, IL-12, or both by infection with corresponding retroviruses. No tumor was observed in 20, 75, and 95% of mice receiving, respectively, B7-1-, IL-12-, and B7-1/IL-12-modified tumor cells after 250 days of inoculation. In contrast, injection of parental BNL or BNL/Neo cells resulted in lethal tumor progression in all mice. Protection against rechallenge with parental tumor cells was observed only in mice who had rejected BNL/IL-12, but not in animals that rejected BNL/B7-1 or BNL/B7-1-IL-12. Growth of parental tumor cells was significantly delayed by simultaneous injection in a distant site of irradiated tumor cells engineered to express IL-12 or both B7-1 and IL-12 but not B7-1 alone. BNL/B7-1 and BNL/B7-1-IL-12 showed similar efficacy in these experiments. Antitumor immunity induced by B7, with or without IL-12, was found to depend mainly on CD4+ T cells with a minor contribution of a non-T cell mechanism; whereas the effect of IL-12 was dependent on CD8+ T cells and on non-T cell effectors. Immunization of mice with IL-12-modified BNL cells induced secretion of a Thl pattern of cytokines while immunization with cells expressing both IL-12 and B7-1 resulted in inhibition of IFN-gamma production. Immunization with BNL/B7-1-IL-12 cells in the presence of anti-human B7-1 MAb resulted in restoration of IFN-gamma production to the levels found in animals injected with BNL/IL-12 cells. To summarize, in our model coexpression of B7-1 and IL-12 in tumor cells does not result in improved antitumoral activity as compared with expression of IL-12 alone. This may be related to the fact that B7-1 changes the mechanisms of antitumor immunity and inhibits IFN-gamma production induced by IL-12 in vivo.

Formaldehyde methods comparison in the remote lower troposphere during the Mauna Loa Photochemistry Experiment 2

NASA Astrophysics Data System (ADS)

Heikes, B.; McCully, B.; Zhou, X.; Lee, Y.-N.; Mopper, K.; Chen, X.; Mackay, G.; Karecki, D.; Schiff, H.; Campos, T.; Atlas, E.

1996-06-01

Five methods for the measurement of CH2O vapor were compared under remote tropospheric conditions. The techniques included an aqueous-scrubber enzyme fluorescence method (URIcoil), TDLAS (UNI), 2,4-dinitrophenylhydrazine (DNPH) impregnated-cartridges (BNL/WSUcart), an aqueous-scrubber DNPH method (BNL/WSUcoil), and an unpublished aqueous-scrubber immobilized-enzyme fluorescence method (NCARbound). This was part of the Mauna Loa Observatory Photochemistry Experiment 2 (MLOPEX 2) which was performed in four ˜30-day intensives. In MLOPEX 2a (fall 1991), the URIcoil technique indicated higher concentrations relative to the BNL/WSUcoil which were higher than UNI. The limited number of NCARbound measurements for MLOPEX 2a were greater than the other measurements and least reliable. During MLOPEX 2b (winter 1992), URIcoil, UNI, BNL/WSUcoil, and NCAR-bound gave comparable measurements of CH2O with the latter again being consistently higher than the first three methods and its performance and reliability was improved over MLOPEX 2a. URIcoil and BNL/WSUcoil were comparable in MLOPEX 2c (spring 1992) and 2d (summer 1992), whereas BNL/WSUcart was consistently higher than both for these intensives. The major source of difference between techniques was ascribed to variations in the analytical-procedural field blanks. Calibration differences were the most likely cause of URIcoil being higher than BNL/WSUcoil and BNL/WSUcoil being higher than UNI during MLOPEX 2a. Lower free troposphere median concentrations were between 100 and 150 ppt for all seasons and without a seasonal trend. These values were a factor of 2 to 3 lower than model estimates for this study site and were in keeping with earlier work.

2006 SITE ENVIRONMENTAL REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

BROOKHAVEN NATIONAL LABORATORY; RATEL,K.

2007-10-01

Each year, Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of BNL's environmental performance during the calendar year in review. The SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and compliance, restoration, and surveillance monitoring program performance. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947.more » The report is available in print and as a downloadable file on the BNL web page at http://www.bnl.gov/ewms/ser/. A summary of the SER is also prepared each year to provide a general overview of the report, and is distributed with a CD of the full report.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ratel, K.M.; Brookhaven National Laboratory

Each year, Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of BNL's environmental performance during the calendar year in review. The SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and compliance, restoration, and surveillance monitoring program performance. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947.more » The report is available in print and as a downloadable file on the BNL web page at http://www.bnl.gov/ewms/ser/. A summary of the SER is also prepared each year to provide a general overview of the report, and is distributed with a CD of the full report.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

BROOKHAVEN NATIONAL LABORATORY

Each year, Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy (DOE). The report is written to inform the public, regulators, employees, and other stakeholders of BNL's environmental performance during the calendar year in review. The SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and compliance, restoration, and surveillance monitoring program performance. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception inmore » 1947. The report is available in print and as a downloadable file on the BNL web page at http://www.bnl.gov/ewms/ser/. A summary of the SER is also prepared each year to provide a general overview of the report, and is distributed with a CD of the full report.« less

Theoretical Study of Operational Limits of High-Speed Quantum Dot Lasers

DTIC Science & Technology

2012-09-09

esc − vLn,captnL − b1 BnL pL, (1) b1 ∂pL ∂ t = p L QW τLp,esc − vLp,capt pL − b1 BnL pL, (2) for free holes and electrons on the right-hand side of...on the left- hand side of the OCL can be written as follows: pLQW τp,esc = vLp,capt pL + b1 BnL pL. (28) Substituting pLQW/τp,esc−vLp,capt pL = b1 BnL ...pL in (6), we have B2Dn L QW p L QW + b1 BnL pL = wLp,tunn pL,QW1 NS fp − wLp,tunn NS(1 − fp)pLQW. (29) As seen from (29), bimolecular recombination

The Drosophila Extradenticle and Homothorax selector proteins control branchless/FGF expression in mesodermal bridge-cells.

PubMed

Merabet, Samir; Ebner, Andreas; Affolter, Markus

2005-08-01

The stereotyped outgrowth of tubular branches of the Drosophila tracheal system is orchestrated by the local and highly dynamic expression profile of branchless (bnl), which encodes a secreted fibroblast growth factor (FGF)-like molecule. Despite the importance of the spatial and temporal bnl regulation, little is known about the upstream mechanisms that establish its complex expression pattern. Here, we show that the Extradenticle and Homothorax selector proteins control bnl transcription in a single cell per segment, the mesodermal bridge-cell. In addition, we observed that a key determinant of bridge-cell specification, the transcription factor Hunchback, is also required for bnl expression. Therefore, we propose that one of the functions of the bridge-cell is to synthesize and secrete the chemoattractant Bnl. These findings provide a hitherto unknown and interesting link between combinatorial inputs of transcription factors, cell-specific ligand expression and organ morphogenesis.

Natural Resource Management Plan for Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

green, T.

This comprehensive Natural Resource Management Plan (NRMP) for Brookhaven National Laboratory (BNL) was built on the successful foundation of the Wildlife Management Plan for BNL, which it replaces. This update to the 2003 plan continues to build on successes and efforts to better understand the ecosystems and natural resources found on the BNL site. The plan establishes the basis for managing the varied natural resources located on the 5,265 acre BNL site, setting goals and actions to achieve those goals. The planning of this document is based on the knowledge and expertise gained over the past 10 years by themore » Natural Resources management staff at BNL in concert with local natural resource agencies including the New York State Department of Environmental Conservation, Long Island Pine Barrens Joint Planning and Policy Commission, The Nature Conservancy, and others. The development of this plan is an attempt at sound ecological management that not only benefits BNL's ecosystems but also benefits the greater Pine Barrens habitats in which BNL is situated. This plan applies equally to the Upton Ecological and Research Reserve (Upton Reserve). Any difference in management between the larger BNL area and the Upton Reserve are noted in the text. The purpose of the Natural Resource Management Plan (NRMP) is to provide management guidance, promote stewardship of the natural resources found at BNL, and to sustainably integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, sustainability, adaptive ecosystem management, compliance, integration with other plans and requirements, and the incorporation of community involvement, where applicable. The NRMP is periodically reviewed and updated, typically every five years. This review and update was delayed to develop documents associated with a new third party facility, the Long Island Solar Farm. This two hundred acre facility will result in significant changes to this plan warranting the delay. The body of this plan establishes the management goals and actions necessary for managing the natural resources at BNL in a sustainable manner. The appendices provide specific management requirements for threatened and endangered amphibians and fish (Appendices A and B, respectively), and lists of actions in tabular format - including completed items as well as ongoing and new action items (Appendices C and D, respectively).« less

Administration of interleukin-12 enhances the therapeutic efficacy of dendritic cell-based tumor vaccines in mouse hepatocellular carcinoma.

PubMed

Tatsumi, T; Takehara, T; Kanto, T; Miyagi, T; Kuzushita, N; Sugimoto, Y; Jinushi, M; Kasahara, A; Sasaki, Y; Hori, M; Hayashi, N

2001-10-15

Dendritic cells (DCs) are potent antigen-presenting cells that are capable of priming systemic antitumor immune response. Here, we evaluated the combined effectiveness of tumor lysate-pulsed DC immunization and interleukin (IL)-12 administration on the induction of antitumor immunity in a mouse hepatocellular carcinoma (HCC) model. Mouse DCs were pulsed with lysate of BNL 1ME A.7R.1 (BNL), a BALB/c-derived HCC cell line, and then injected into syngeneic mice in combination with systemic administration of IL-12. Lymphocytes from mice treated with BNL lysate-pulsed DCs and IL-12 showed stronger cytolytic activity and produced higher amounts of IFN-gamma than those from mice treated with BNL lysate-pulsed DCs alone. Although immunization with BNL lysate-pulsed DCs alone did not lead to complete regression of established tumors, it significantly inhibited tumor growth compared with vehicle injection. Importantly, the combined therapy of BNL lysate-pulsed DCs and IL-12 resulted in tumor rejection or significant inhibition of tumor growth compared with mice treated with BNL lysate-pulsed DCs alone. In vivo lymphocyte depletion experiments demonstrated that this combination was dependent on both CD8+ and CD4+ T cells, but not natural killer cells. These results demonstrated that IL-12 administration enhanced the therapeutic effect of immunization of tumor lysate-pulsed DCs against HCC in mice. This combination of IL-12 and DCs may be useful for suppressing the growth of residual tumor after primary therapy of human HCC.

Ionizing radiation potentiates the induction of nitric oxide synthase by interferon-gamma (Ifn-gamma) or Ifn-gamma and lipopolysaccharide in bnl cl.2 murine embryonic liver cells: role of hydrogen peroxide.

PubMed

Yoo, J C; Pae, H O; Choi, B M; Kim, W I; Kim, J D; Kim, Y M; Chung, H T

2000-02-01

The effects of ionizing irradiation on the nitric oxide (NO) production in murine embryonic liver cell line, BNL CL.2 cells, were investigated. Various doses (5-40 Gy) of radiation made BNL CL.2 cells responsive to interferon-gamma alone for the production of NO in a dose-dependent manner. Small amounts of lipopolysaccharide (LPS) or tumor necrosis factor-alpha (TNF-alpha) synergized with IFN-gamma in the production of NO from irradiated BNL CL.2 cells, even though LPS or TNF-alpha alone did not induce NO production from the same cells. Immunoblots showed parallel induction of inducible nitric oxide synthase (iNOS). NO production in irradiated BNL CL.2 cells by IFN-gamma or IFN-gamma plus LPS was decreased by the addition of catalase, suggesting that H(2)O(2) produced by ionizing irradiation primed the cells to trigger NO production in response to IFN-gamma or IFN-gamma plus LPS. Furthermore, the treatment of nongamma-irradiated BNL CL.2 cells with H(2)O(2) made the cells responsive to IFN-gamma or IFN-gamma plus LPS for the production of NO. This study shows that ionizing irradiation has the ability to induce iNOS gene expression in responsive to IFN-gamma via the formation of H(2)O(2) in BNL CL.2 murine embryonic liver cells.

Low-pressure Structural Modification of Aluminum Hydride

DTIC Science & Technology

2011-02-01

Acknowledgments Use of the National Synchrotron Light Source (NSLS), Brookhaven National Laboratory ( BNL ) was supported by the U.S. Department of Energy...National Synchrotron Light Source (NSLS) of Brookhaven National Laboratory ( BNL ). The spectral resolution of ±4 cm–1 was used for all IR measurements...12 List of Symbols, Abbreviations, and Acronyms Al aluminum AlH3 aluminum hydride BNL Brookhaven National Laboratory EOS equation of

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green,T.

This Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) updates the 2003 plan incorporating changes necessary to comply with DOE Order 450.1 and DOE P 450.4, Federal Wildland Fire Management Policy and Program Review; Wildland and Prescribed Fire Management Policy and implementation Procedures Reference Guide. This current plan incorporates changes since the original draft of the FMP that result from new policies on the national level. This update also removes references and dependence on the U.S. Fish & Wildlife Service and Department of the Interior, fully transitioning Wildland Fire Management responsibilities to BNL. The Department of Energy policymore » for managing wildland fires requires that all areas, managed by the DOE and/or its various contractors, that can sustain fire must have a FMP that details fire management guidelines for operational procedures associated with wild fire, operational, and prescribed fires. Fire management plans provide guidance on fire preparedness, fire prevention, wildfire suppression, and the use of controlled, 'prescribed' fires and mechanical means to control the amount of available combustible material. Values reflected in the BNL Wildland FMP include protecting life and public safety; Lab properties, structures and improvements; cultural and historical sites; neighboring private and public properties; and endangered, threatened, and species of concern. Other values supported by the plan include the enhancement of fire-dependent ecosystems at BNL. This FMP will be reviewed periodically to ensure the fire program advances and evolves with the missions of the DOE and BNL. This Fire Management Plan is presented in a format that coverers all aspects specified by DOE guidance documents which are based on the national template for fire management plans adopted under the National Fire Plan. The DOE is one of the signatory agencies on the National Fire Plan. This FMP is to be used and implemented for the entire BNL site including the Upton Reserve and has been reviewed by, The Nature Conservancy, New York State Department of Environmental Conservation Forest Rangers, and DOE, as well as appropriate BNL emergency services personnel. The BNL Fire Department is the lead on wildfire suppression. However, the BNL Natural Resource Manager will be assigned to all wildland fires as technical resource advisor.« less

Selected text of Atomic Energy Act, Executive Orders and other laws of general interest to safeguards and security executives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cadwell, J.J.; Ruger, C.J.

1995-12-01

This document is one of a three report set, BNL 52201 contains detailed information for use by executives. BNL 52202 is titled, U.S. Statutes of General Interest to Safeguards and Security Officers, and contains less detail than BNL 52201. It is intended for use by officers. BNL 52203 is titled, U.S.Statutes for Enforcement by Security Inspectors, and only contains statutes to be applied by uniformed security inspectors. These are a newly updated version of a set of documents of similar titles published in September 1988, which were an updated version of an original set of documents published in November 1983.

First test of BNL electron beam ion source with high current density electron beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pikin, Alexander, E-mail: pikin@bnl.gov; Alessi, James G., E-mail: pikin@bnl.gov; Beebe, Edward N., E-mail: pikin@bnl.gov

A new electron gun with electrostatic compression has been installed at the Electron Beam Ion Source (EBIS) Test Stand at BNL. This is a collaborative effort by BNL and CERN teams with a common goal to study an EBIS with electron beam current up to 10 A, current density up to 10,000 A/cm{sup 2} and energy more than 50 keV. Intensive and pure beams of heavy highly charged ions with mass-to-charge ratio < 4.5 are requested by many heavy ion research facilities including NASA Space Radiation Laboratory (NSRL) at BNL and HIE-ISOLDE at CERN. With a multiampere electron gun, themore » EBIS should be capable of delivering highly charged ions for both RHIC facility applications at BNL and for ISOLDE experiments at CERN. Details of the electron gun simulations and design, and the Test EBIS electrostatic and magnetostatic structures with the new electron gun are presented. The experimental results of the electron beam transmission are given.« less

Reform of the National Security Science and Technology Enterprise

DTIC Science & Technology

2008-10-01

still attract the very best S&E talent.54 Table 1. National Academy Membership (Source: National Academies Website) ANL BNL JPL LANL LL LLNL IBM...ANL BNL JPL LANL LLNL NIH NIST NRL Articles 1023 761 705 1526 1038 4305 350 957 Government S&E Workforce—Tomorrow With the significant exception...ANL), Brookhaven National Laboratory ( BNL ), Jet Propulsion Laboratory (JPL), Lincoln Laboratory (LL), Los Alamos National Laboratory (LANL

Non-Leaching, Benign Antifouling Multilayer Polymer Coatings for Marine Applications

DTIC Science & Technology

2010-03-01

polymerization b block BF3•Et2O boron trifluoride diethyl etherate BNL Brookhaven National Labs BF3•Et2O boron trifluoride diethyl etherate BSA...surface characterization of the polymers. We also acknowledge Brookhaven National Laboratory ( BNL ) where the NEXAFS surface characterization was...National Synchrotron Light Source at Brookhaven National Laboratory ( BNL ). The X-ray beam was elliptically polarized (polarization factor = 0.85

Selective effects of quercetin on the cell growth and antioxidant defense system in normal versus transformed mouse hepatic cell lines.

PubMed

Son, Young-Ok; Lee, Kyung-Yeol; Kook, Sung-Ho; Lee, Jeong-Chae; Kim, Jong-Ghee; Jeon, Young-Mi; Jang, Yong-Suk

2004-10-19

Quercetin is a dietary anticancer chemical that is capable of inducing apoptosis in tumor cells. However, little is known about its biological effect on nonmalignant cells, although the effect is one of the critical criteria to evaluate the clinical efficacy of the anticancer agent. In this study, we investigated the effects of quercetin on cell growth and apoptosis using embryonic normal hepatic cell line (BNL CL.2) and its SV40-transformed cell line (BNL SV A.8). We also evaluated the effects of quercetin on the antioxidant defense system in those cells. BNL SV A.8 cells were more sensitive to quercetin-mediated cytotoxicity than BNL CL.2 cells. In addition, the enzyme assays showed that quercetin actively stimulated the antioxidant defense systems including superoxide dismutase, catalase, glutathione, and glutathione reductase only in the BNL CL.2 cells. In particular, quercetin significantly reduced superoxide dismutase activity and increased the malonaldehyde content in BNL SV A.8 cells. These are thought to be closely related to quercetin-mediated apoptosis. Our findings suggest that quercetin is a dietary flavonoid that is capable of inducing selective growth inhibition and apoptosis in hepatic tumor cells, but not in normal cells.

Drug resistance reversal in ovarian cancer cells of paclitaxel and borneol combination therapy mediated by PEG-PAMAM nanoparticles.

PubMed

Zou, Liang; Wang, Di; Hu, Yichen; Fu, Chaomei; Li, Wei; Dai, Liping; Yang, Lin; Zhang, Jinming

2017-09-01

Paclitaxel (PTX) is frequently suffered from multidrug resistance (MDR), resulting in lower chemotherapeutic efficacy and even chemotherapy failure. To combine the P-glycolprotein (P-gp) inhibitor would be a useful strategy to overcome MDR. However, what is needed now is an efficient vehicle to deliver multiple drugs into tumor simultaneously. In this study, PTX and Borneol (BNL), a natural compound with P-gp inhibition effect confirmed in intestinal absorption, were co-loaded in the fabricated PEG-PAMAM nanoparticle (NPs) by a one-step nano-precipitation method with high drug loading efficiency, narrow size distribution and low hemolysis rate. Based on P-gp inhibition activity of BNL, confirmed by drug efflux test and molecular docking model, the combination of PTX and BNL could improve intracellular concentration of PTX in A2780/PTX cells. Furthermore, compared to both free PTX and PTX+BNL, PB/NPs and P/NPs plus BNL exhibited higher cellular uptake and cytotoxicity in A2780/PTX cells, as well as the decreased MMP and enhanced apoptosis rate. More importantly, although PB/NPs and P/NPs+B showed similar tumor accumulation in tumor-bearing mice, PB/NPs could significantly decrease tumor growth of A2780/PTX tumor-bearing mice, in comparison to P/NPs+B. These results indicated the advantage of PTX and BNL co-delivery NPs for MDR reversal. These findings demonstrate that the co-delivery nano-sized system comprised by PEG-PAMAM polymer with PTX and BNL co-loaded would be a promising candidate for MDR treatment.

Drug resistance reversal in ovarian cancer cells of paclitaxel and borneol combination therapy mediated by PEG-PAMAM nanoparticles

PubMed Central

Zou, Liang; Wang, Di; Hu, Yichen; Fu, Chaomei; Li, Wei; Dai, Liping; Yang, Lin; Zhang, Jinming

2017-01-01

Paclitaxel (PTX) is frequently suffered from multidrug resistance (MDR), resulting in lower chemotherapeutic efficacy and even chemotherapy failure. To combine the P-glycolprotein (P-gp) inhibitor would be a useful strategy to overcome MDR. However, what is needed now is an efficient vehicle to deliver multiple drugs into tumor simultaneously. In this study, PTX and Borneol (BNL), a natural compound with P-gp inhibition effect confirmed in intestinal absorption, were co-loaded in the fabricated PEG-PAMAM nanoparticle (NPs) by a one-step nano-precipitation method with high drug loading efficiency, narrow size distribution and low hemolysis rate. Based on P-gp inhibition activity of BNL, confirmed by drug efflux test and molecular docking model, the combination of PTX and BNL could improve intracellular concentration of PTX in A2780/PTX cells. Furthermore, compared to both free PTX and PTX+BNL, PB/NPs and P/NPs plus BNL exhibited higher cellular uptake and cytotoxicity in A2780/PTX cells, as well as the decreased MMP and enhanced apoptosis rate. More importantly, although PB/NPs and P/NPs+B showed similar tumor accumulation in tumor-bearing mice, PB/NPs could significantly decrease tumor growth of A2780/PTX tumor-bearing mice, in comparison to P/NPs+B. These results indicated the advantage of PTX and BNL co-delivery NPs for MDR reversal. These findings demonstrate that the co-delivery nano-sized system comprised by PEG-PAMAM polymer with PTX and BNL co-loaded would be a promising candidate for MDR treatment. PMID:28947984

DOE Office of Scientific and Technical Information (OSTI.GOV)

BENNETT,D.B.; PAQUETTE,D.E.; KLAUS,K.

The BNL water supply system meets all water quality standards and has sufficient pumping and storage capacity to meet current and anticipated future operational demands. Because BNL's water supply is drawn from the shallow Upper Glacial aquifer, BNL's source water is susceptible to contamination. The quality of the water supply is being protected through (1) a comprehensive program of engineered and operational controls of existing aquifer contamination and potential sources of new contamination, (2) groundwater monitoring, and (3) potable water treatment. The BNL Source Water Assessment found that the source water for BNL's Western Well Field (comprised of Supply Wellsmore » 4, 6, and 7) has relatively few threats of contamination and identified potential sources are already being carefully managed. The source water for BNL's Eastern Well Field (comprised of Supply Wells 10, 11, and 12) has a moderate number of threats to water quality, primarily from several existing volatile organic compound and tritium plumes. The g-2 Tritium Plume and portions of the Operable Unit III VOC plume fall within the delineated source water area for the Eastern Well Field. In addition, portions of the much slower migrating strontium-90 plumes associated with the Brookhaven Graphite Research Reactor, Waste Concentration Facility and Building 650 lie within the Eastern source water area. However, the rate of travel in the aquifer for strontium-90 is about one-twentieth of that for tritium and volatile organic compounds. The Laboratory has been carefully monitoring plume migration, and has made adjustments to water supply operations. Although a number of BNL's water supply wells were impacted by VOC contamination in the late 1980s, recent routine analysis of water samples from BNL's supply wells indicate that no drinking water standards have been reached or exceeded. The high quality of the water supply strongly indicates that the operational and engineered controls implemented over the past ten years have effectively protected the quality of the water supply.« less

Laboratory Directed Research and Development Program Assessment for FY 2008

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney, J P; Fox, K J

2008-03-31

Brookhaven National Laboratory (BNL) is a multidisciplinary Laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2008 spending was $531.6 million. There are approximately 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annuallymore » in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. To be a premier scientific Laboratory, BNL must continuously foster groundbreaking scientific research and renew its research agenda. The competition for LDRD funds stimulates Laboratory scientists to think in new and creative ways, which becomes a major factor in achieving and maintaining research excellence and a means to address National needs within the overall mission of the DOE and BNL. By fostering high-risk, exploratory research, the LDRD program helps BNL to respond new scientific opportunities within existing mission areas, as well as to develop new research mission areas in response to DOE and National needs. As the largest expense in BNL's LDRD program is the support graduate students, post-docs, and young scientists, LDRD provides base for continually refreshing the research staff as well as the education and training of the next generation of scientists. The LDRD Program Assessment Report contains a review of the program. The report includes a summary of the management processes, project peer review, and the portfolio's relatedness to BNL's mission, initiatives and strategic plans. Also included are a metric of success indicators and Self Assessment.« less

Physics of Radiation Exposure and Characterization for Future Electronic Materials

DTIC Science & Technology

2014-12-01

TEM probe. These visits have included an invited talk at the Annual User’s Meeting at BNL in which the DTRA project was highlighted. • Columbia...at PNNL. • Columbia graduate student Luozhou Li was trained by BNL researchers Dr. Ming Lu on nanofabrication techniques related to the fabrication...Jacob Mower were trained by BNL researcher Kim Kisslinger on diamond membrane fabrication and TEM cross-section sample fabrication. • Columbia

Public-Private Sector Passenger Rail Intelligence and Terrorism Information Sharing

DTIC Science & Technology

2008-09-01

surrounding the illegal activities of the Banca Nazionale del Lavoro ( BNL ) and the Bank of Credit and Commercial International (BCCI) during the early...IC_Information_Sharing_Strategy.pdf (accessed June 8, 2008). 2 presented in the BNL case. Indeed, as the conclusions set forth below indicate, there are...4 Senate Select Committee on Intelligence, The Intelligence Community’s Involvement in the Banca Nazionale del Lavoro ( BNL ) Affair (Washington, D.C

DOE Office of Scientific and Technical Information (OSTI.GOV)

ENVIRONMENTAL AND WASTE MANAGEMENT SERVICES DIVISION

This Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) and the Upton Ecological and Research Reserve (Upton Reserve) is based on the U.S. Fish & Wildlife Service (FWS) fire management planning procedures and was developed in cooperation with the Department of Energy (DOE) by Brookhaven Science Associates. As the Upton Reserve is contained within the BNL 5,265-acre site, it is logical that the plan applies to both the Upton Reserve and BNL. The Department of the Interior policy for managing wildland fires requires that all areas managed by FWS that can sustain fire must have an FMP thatmore » details fire management guidelines for operational procedures and specifies values to be protected or enhanced. Fire management plans provide guidance on fire preparedness, fire prevention, wildfire suppression, and the use of controlled, ''prescribed'' fires and mechanical means to control the amount of available combustible material. Values reflected in the BNL/Upton Reserve Wildland FMP include protecting life and public safety; Lab properties, structures and improvements; cultural and historical sites; neighboring private and public properties; and endangered and threatened species and species of concern. Other values supported by the plan include the enhancement of fire-dependent ecosystems at BNL and the Upton Reserve. This FMP will be reviewed periodically to ensure the fire program advances and evolves with the missions of FWS, BNL, and the Upton Reserve. This Fire Management Plan is a modified version of the Long Island National Wildlife Refuge Complex Fire plan (updated in 2000), which contains all FWS fire plan requirements and is presented in the format specified by the national template for fire management plans adopted under the National Fire Plan. The DOE is one of the signatory agencies on the National Fire Plan. FWS shall be, through an Interagency Agreement dated November 2000 (Appendix C), responsible for coordinating and implementing prescribed burns and fuel reduction projects in the Upton Reserve. Prescribed fire and fuel reduction in locations outside the Upton Reserve will be coordinated through the Natural Resource Management Program at BNL, and done in consultation with FWS. This FMP is to be used and implemented for the entire BNL site including the Upton Reserve and has been reviewed by FWS, The Nature Conservancy, New York State Department of Environmental Conservation Forest Rangers, and DOE, as well as appropriate BNL emergency services personnel.« less

The bHLH transcription factor, hairy, refines the terminal cell fate in the Drosophila embryonic trachea.

PubMed

Zhan, Yaoyao; Maung, Saw W; Shao, Bing; Myat, Monn Monn

2010-11-30

The pair-rule gene, hairy, encodes a basic helix-loop-helix transcription factor and is required for patterning of the early Drosophila embryo and for morphogenesis of the embryonic salivary gland. Although hairy was shown to be expressed in the tracheal primordia and in surrounding mesoderm, whether hairy plays a role in tracheal development is not known. Here, we report that hairy is required for refining the terminal cell fate in the embryonic trachea and that hairy's tracheal function is distinct from its earlier role in embryonic patterning. In hairy mutant embryos where the repressive activity of hairy is lost due to lack of its co-repressor binding site, extra terminal cells are specified in the dorsal branches. We show that hairy functions in the muscle to refine the terminal cell fate to a single cell at the tip of the dorsal branch by limiting the expression domain of branchless (bnl), encoding the FGF ligand, in surrounding muscle cells. Abnormal activation of the Bnl signaling pathway in hairy mutant tracheal cells is exemplified by increased number of dorsal branch cells expressing Bnl receptor, Breathless (Btl) and Pointed, a downstream target of the Bnl/Btl signaling pathway. We also show that hairy genetically interacts with bnl in TC fate restriction and that overexpression of bnl in a subset of the muscle surrounding tracheal cells phenocopied the hairy mutant phenotype. Our studies demonstrate a novel role for Hairy in restriction of the terminal cell fate by limiting the domain of bnl expression in surrounding muscle cells such that only a single dorsal branch cell becomes specified as a terminal cell. These studies provide the first evidence for Hairy in regulation of the FGF signaling pathway during branching morphogenesis.

The policy of the Laboratory is to provide a safe and healthy workplace for

Science.gov Websites

group within the Collider Accelerator (C-A) Department. The Advanced Accelerator Group, a group within ://www.tvdg.bnl.gov/index.html that also has links to the C-A and other BNL information. We hope your stay at policies are outlined in the Employees' Handbook, the BNL ES&H Standards the C-A Operations Procedure

Effect of Mixture Pressure and Equivalence Ratio on Detonation Cell Size for Hydrogen-Air Mixtures

DTIC Science & Technology

2015-06-01

National Labs ( BNL ) built and tested several detonation tubes with hydrogen and air detonations. BNL’s main detonation tubes were called the High...K and the ability to change to mixture pressure from one atmosphere to just less than three atmospheres. Before BNL designed their detonation tubes...gas driver initiation system was that the diaphragm had to be replaced after each test. In order to save time from replacing the diaphragms, BNL

Evidence for Solar Influences on Nuclear Decay Rates

DTIC Science & Technology

2010-07-01

collected at Brookhaven National Laboratory ( BNL ) measuring 32Si and 36Cl,2,3,5–7 and 226Ra data collected at the Physikalisch-Technische Bundesanstalt...conditions. In what follows we present several arguments against a simplistic, systematic explanation of the BNL and PTB data fluctuations in terms of...any known seasonal environmental effect.4 (2) In both the BNL experiment, which studied 32Si and 36Cl in the same detector,7 and the CNRC (Children’s

Protective effects of fucoxanthin against ferric nitrilotriacetate-induced oxidative stress in murine hepatic BNL CL.2 cells.

PubMed

Liu, Cheng-Ling; Liang, Ai-Ling; Hu, Miao-Lin

2011-10-01

Fucoxanthin is a carotenoid that is rich in some seaweed. Although fucoxanthin has been reported to possess radical-scavenging activities in vitro, little is known whether it may protect against iron-induced oxidative stress in cultured cells. In this study, we examined the protection of fucoxanthin against oxidative damage in BNL CL.2 cells induced by ferric nitrilotriacetate (Fe-NTA). The data show that incubation of BNL CL.2 cells with Fe-NTA for 30 min significantly decreased cell proliferation, whereas pretreatment with fucoxanthin (1-20 μΜ) for 24h significantly recovered cell proliferation in a dose-dependent manner. In addition, fucoxanthin pretreatment significantly decreased intracellular reactive oxygen species (ROS) and DNA damage in BNL CL.2 cells incubated with Fe-NTA for 30 min. Moreover, fucoxanthin markedly decreased the level of thiobarbituric acid-reactive substances (TBARS) and protein carbonyl contents in BNL CL.2 cells induced by Fe-NTA. By contrast, fucoxanthin significantly increased the levels of GSH in a concentration-dependent manner. These results demonstrate that fucoxanthin at 1-20μΜ effectively prevents cytotoxicity in BNL CL.2 cells treated with Fe-NTA, and that the protective effect is likely associated with decreased intracellular ROS, TBARS, protein carbonyl contents and increased GSH levels. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

Instrument Development of Real Time Holographic Water Drop Size Measurement System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springston, Stephen

2007-02-09

BNL participated with multiple correspondences with Physical Optics Corporation (POC) on the design considerations of an airbome instrument. A pod for extemal deployment ofthe POC unit on the DOE Research Aircraft Facility (RAF), an instrumented, Grumman G-1 aircraft was loaned to POC. BNL proposed evaluation flight tests between the POC unit and the BNL Cloud Aerosol Probe Spectrometer (CAPS) as a reference method. BNL's involvement is described in the semi-annual report ofPOC to DOE. Because of unanticipated technical and engineering difficulties, POC was unable to fit their instrument into an aircraft pod. As a result they are now focusing onmore » a ground-based version first. A prototype laboratory version of the Real-Time Holographic Water Drop Size Measurement (WDSM) System has been constructed.« less

NOTE: Total body-calcium measurements: comparison of two delayed-gamma neutron activation facilities

NASA Astrophysics Data System (ADS)

Ma, R.; Ellis, K. J.; Yasumura, S.; Shypailo, R. J.; Pierson, R. N., Jr.

1999-06-01

This study compares two independently calibrated delayed-gamma neutron activation (DGNA) facilities, one at the Brookhaven National Laboratory (BNL), Upton, New York, and the other at the Children's Nutrition Research Center (CNRC), Houston, Texas that measure total body calcium (TBCa). A set of BNL phantoms was sent to CNRC for neutron activation analysis, and a set of CNRC phantoms was measured at BNL. Both facilities showed high precision (<2%), and the results were in good agreement, within 5%.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ratel, K.; Lee, R; Remien, J

Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inceptionmore » in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in Chapter 7, Groundwater Protection, of this volume. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the full report. BNL is operated and managed for DOE's Office of Science by Brookhaven Science Associates (BSA), a partnership formed by Stony Brook University and Battelle Memorial Institute. For more than 60 years, the Laboratory has played a lead role in the DOE Science and Technology mission and continues to contribute to the DOE missions in energy resources, environmental quality, and national security. BNL manages its world-class scientific research with particular sensitivity to environmental issues and community concerns. The Laboratory's motto, 'Exploring Life's Mysteries...Protecting its Future,' and its Environmental, Safety, Security and Health Policy reflect the commitment of BNL's management to fully integrate environmental stewardship into all facets of its mission and operations.« less

The protective effect of intrasplenic transplantation of Ad-IL-18BP/IL-4 gene-modified fetal hepatocytes on ConA-induced hepatitis in mice.

PubMed

Shao, Xueting; Qian, Yun; Xu, Chenhuai; Hong, Bo; Xu, Wanhong; Shen, Ling; Jin, Changzhong; Wu, Zhigang; Tong, Xiangmin; Yao, Hangping

2013-01-01

Concanavalin A (ConA)-induced hepatitis is an experimental murine model mirroring the pathology of human autoimmune hepatitis. To investigate the effects of intrasplenically transplanted fetal hepatocytes (BNL.CL2) transfected with recombinant adenovirus vector expressing the IL-18 binding protein (IL-18BP) and IL-4 fusion protein on ConA-induced hepatitis in mice. Ad-IL-18BP/IL-4 was used to infect BNL.CL2 cells. IL-4 and IL-18BP fusion protein expression were detected by ELISA and Western blotting. BNL.CL2 cells infected with Ad-IL-18BP/IL-4 were intrasplenically transplanted into mice. After 10 days, mice were injected with ConA (15 mg/kg), and sacrificed 18 hours later. Liver injury was assessed by serum transaminase and liver histology. TNF-α, IL-18, IL-4, IL-10, IL-12p70 and monocyte-chemoattracting protein (MCP)-1 levels in serum and liver homogenates were detected by ELISA. Signaling molecules in liver homogenates were analyzed by Western blotting. Ad-IL-18BP/IL-4 effectively expressed the IL-18BP/IL-4 fusion protein for more than 14 days in BNL.CL12 cells. Treatment of mice with Ad-IL-18BP/IL-4-BNL.CL2 before ConA injection significantly reduced the elevated plasma levels of transaminases compared with ConA control groups. TNF-α, IL-18, IL-12p70 and MCP-1 levels in serum and liver homogenates from mice transplanted with Ad-IL-18BP/IL-4-BNL.CL2 were lower and IL-4 and IL-10 levels were higher than control groups. Phosphorylation levels of NF-κB p65, AKT, p38 and JNK1/2 in liver homogenates were markedly suppressed by Ad-IL-18BP/IL-4. Ad-IL-18BP/IL-4 was effectively transfected into mouse BNL.CL2 cells. Intrasplenic transplantation of Ad-IL-18BP/IL-4-BNL.CL12 cells alleviated the severity of inflammation in ConA-induced experimental hepatitis and provides a useful basis for the targeted gene therapy of liver disease.

116 kDa glycoprotein isolated from Ulmus davidiana Nakai (UDN) inhibits glucose/glucose oxidase (G/GO)-induced apoptosis in BNL CL.2 cells.

PubMed

Ko, Jeong-Hyeon; Lee, Sei-Jung; Lim, Kye-Taek

2005-09-14

Ulmus davidiana Nakai (UDN) has been used in folk medicine for its anti-inflammatory activity. In the present study, we investigated the antiapoptotic effect of UDN glycoprotein in glucose/glucose oxidase (G/GO)-induced BNL CL.2 cells. To evaluate the antiapoptotic effect of UDN glycoprotein, experiments were carried out using Western blot analysis for nuclear factor-kappa B (NF-kappaB), caspase-3, and poly(ADP-ribose) polymerase (PARP). We also examined nitric oxide (NO) production and nuclear staining. When BNL CL.2 cells were treated with G/GO (50 mU/ml), viability of the cells was 54.1%. However, the number of living cells after the addition of UDN glycoprotein in the presence of G/GO increased. UDN glycoprotein protected from cell damage caused by G/GO. Interestingly, UDN glycoprotein decreased NF-kappaB activation and stimulated NO production in G/GO-induced BNL CL.2 cells. In apoptotic parameters, UDN glycoprotein inhibited activations of caspase-3 and PARP cleavage in G/GO-induced BNL CL.2 cells. The results of nuclear staining indicated that UDN glycoprotein (50 microg/ml) has a protective ability from apoptotic cell death caused G/GO (50 mU/ml). In conclusion, UDN glycoprotein has a protective effect on apoptosis induced by G/GO through the inhibition of NF-kappaB, caspase-3, and PARP activity, and the stimulation of NO production in BNL CL.2 cells.

Pollution, contamination and future land use at Brookhaven National Laboratory.

PubMed

Burger, J; Gochfeld, M; Shukla, S; Jeitner, C; Ramos, R; Tsipoura, Nellie; Donio, M

2008-10-01

Scientists interested in contamination normally deal only with pollution itself, not with people's perceptions of pollution or the relationship between pollution and land use. The overall objective of this article was to examine the relationship between people's perceptions of pollution and their views on future land use. People were interviewed at an Earth Day Festival near the Department of Energy's Brookhaven National Laboratory (BNL) on Long Island, New York. On an open-ended question, people thought that BNL should be left as it is, or maintained as a preserve, park or conservation area, or used for environmental research. Almost no one thought that it should be used for housing or industrial purposes. When asked to rate a list of possible future land uses, maintaining BNL as a National Environmental Research Park for research and for recreation were rated the highest (nuclear storage was rated the lowest). This was consistent with the subjects' views that pollution was the greatest concern about BNL. The congruence between perceptions about concerns or problems and future land use preferences suggests a unified view of management of contaminated sites, such as BNL, at least among a group of people whose environmental interests were evident by their presence at the event.

LDRD 2014 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, Diane

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2014, as required. In FY 2014, the BNL LDRD Program funded 40 projects, 8 of which were new starts, at a total cost of $9.6M.

LDRD 2012 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bookless, William

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY2012, as required. In FY2012, the BNL LDRD Program funded 52 projects, 14 of which were new starts, at a total cost of $10,061,292.

Simulations to Evaluate Accuracy and Patient Dose in Neutron-Stimulated, Emission-Computed Tomography (NSECT) for Diagnosis of Breast Cancer

DTIC Science & Technology

2009-04-01

table 1 and includes all of the excited state transitions that are included in the BNL database. In this study we considered only states that could be...16Cross Section Evaluation Working Group, ENDEIB-VI Summary Docu- mentation, Report BNL -NCS-17541 ENDF-201, edited by P. F. Rose, National Nuclear Data...Med. Phys., vol. 34, pp. 3866–3871, 2007. [37] National Nuclear Data Center BNL , NuDat 2.3 2007. [38] A. J. Kapadia and C. E. Floyd, “An attenuation

LDRD 2015 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, D.

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2015, as required. In FY 2015, the BNL LDRD Program funded 43 projects, 12 of which were new starts, at a total cost of $9.5M.

Limiting Index Sort: A New Non-Dominated Sorting Algorithm and its Comparison to the State-of-the-Art

DTIC Science & Technology

2010-05-01

Skyline Algorithms 2.2.1 Block-Nested Loops A simple way to find the skyline is to use the block-nested loops ( BNL ) algorithm [3], which is the algorithm...by an NDS member are discarded. After every individual has been compared with the NDS, the NDS is the dataset’s skyline. In the best case for BNL ...SFS) algorithm [4] is a variation on BNL that first introduces the idea of initially ordering the individuals by a monotonically increasing scoring

Development and Simulation Studies of a Novel Electromagnetics Code

DTIC Science & Technology

2011-10-20

121 Bibliography 123 LIST OF TABLES xii List of Tables 3.1 The rf photoinjector beam parameters of the BNL 2.856 GHz and the ANL AWA 1.3 GHz guns...examples of field plots. The space-charge fields are numerically computed with the parameters of BNL 2.856 GHz gun. Figure 3.2 shows a 3D plot of Er vs...the BNL 2.856 GHz and the ANL AWA 1.3 GHz guns. The main gun parameters are given in the Table 3.1. The distribution of the bunched beam can be

Production of DOUBLE-Λ Hypernuclei:. Bnl-Ags E906

NASA Astrophysics Data System (ADS)

Fukuda, T.; Nagae, T.; Outa, H.; Sekimoto, M.; Hotchi, H.; Miyachi, T.; Nakano, J.; Tamagawa, T.; Tanida, K.; Chrien, R. E.; May, M.; Meyer, E.; Pile, P.; Rusek, A.; Sutter, R.; Berdoz, A.; Carman, D.; Eugenio, P.; Franklin, G. B.; Khaustov, P.; Koran, P.; Meyer, C.; Paschke, K.; Quinn, B. P.; Schumacher, R. A.; Gan, L.; Tang, L.; Yuan, L.; Kurepin, A.; Rasin, V.; Prokhavatilov, M.; Shileev, K.; Ahn, J. K.; Akikawa, H.; Imai, K.; Ichikawa, A.; Yamamoto, K.; Yosoi, M.; Ajimura, S.; Kishimoto, T.; Kori, H.; Minami, S.; Shimizu, Y.; Meziani, Z.; Fischer, H.; Franz, J.; Schmitt, H.; Davis, C. A.; Landry, M.; Bassalleck, B.

2000-09-01

We have carried out an experiment at BNL-AGS (E906) to search for double-Λ hypernuclei by observing sequential pionic decays. We will describe the principle of the experiment and report the present status.

Bertram Brockhouse, the Triple-axis Spectrometer, and Neutron Spectroscopy

Science.gov Websites

foreign guest scientist in the Reactor Department at Brookhaven National Laboratory [BNL]. During this and light and heavy water ... .'1 Brockhouse was again a foreign guest scientist at BNL in 1970. He

Glycoprotein (116 kD) isolated from Ulmus davidiana Nakai protects from injury of 12-O-tetradecanoylphorbol 13-acetate (TPA)-treated BNL CL.2 cells.

PubMed

Oh, Phil-Sun; Lee, Sei-Jung; Lim, Kye-Taek

2006-01-01

Ulmus davidiana Nakai (UDN) has been used for a long time to cure inflammation in oriental medicine. To evaluate the cytoprotective effects of the UDN glycoprotein, we measured cytotoxicity, the level of intracellular reactive oxygen species (ROS), activity of nuclear factor-kappaB (NF-kappaB), nitric oxide (NO) production, and thiobarbituric acid-reactive substances (TBARS) formation in 12-O-tetradecanoylphorbol 13-acetate (TPA)-treated BNL CL.2 cells. In TPA-treated BNL CL.2 cells, the results showed that UDN glycoprotein has dose-dependent blocking activities against TPA-induced cytotoxicity and NF-kappaB activation. In cytotoxic-related events, UDN glycoprotein (200 microg/ml) has an inhibitory effect on intracellular ROS production, NO production, and TBARS formation, without any toxic effects in the BNL CL.2 cells. These results suggest that UDN glycoprotein has cytoprotective abilities against TPA-induced oxidative cell injury.

The Protective Effect of Intrasplenic Transplantation of Ad-IL-18BP/IL-4 Gene-Modified Fetal Hepatocytes on ConA-Induced Hepatitis in Mice

PubMed Central

Xu, Chenhuai; Hong, Bo; Xu, Wanhong; Shen, Ling; Jin, Changzhong; Wu, Zhigang; Tong, Xiangmin; Yao, Hangping

2013-01-01

Background Concanavalin A (ConA)-induced hepatitis is an experimental murine model mirroring the pathology of human autoimmune hepatitis. Aim To investigate the effects of intrasplenically transplanted fetal hepatocytes (BNL.CL2) transfected with recombinant adenovirus vector expressing the IL-18 binding protein (IL-18BP) and IL-4 fusion protein on ConA-induced hepatitis in mice. Methods Ad-IL-18BP/IL-4 was used to infect BNL.CL2 cells. IL-4 and IL-18BP fusion protein expression were detected by ELISA and Western blotting. BNL.CL2 cells infected with Ad-IL-18BP/IL-4 were intrasplenically transplanted into mice. After 10 days, mice were injected with ConA (15 mg/kg), and sacrificed 18 hours later. Liver injury was assessed by serum transaminase and liver histology. TNF-α, IL-18, IL-4, IL-10, IL-12p70 and monocyte-chemoattracting protein (MCP)-1 levels in serum and liver homogenates were detected by ELISA. Signaling molecules in liver homogenates were analyzed by Western blotting. Results Ad-IL-18BP/IL-4 effectively expressed the IL-18BP/IL-4 fusion protein for more than 14 days in BNL.CL12 cells. Treatment of mice with Ad-IL-18BP/IL-4-BNL.CL2 before ConA injection significantly reduced the elevated plasma levels of transaminases compared with ConA control groups. TNF-α, IL-18, IL-12p70 and MCP-1 levels in serum and liver homogenates from mice transplanted with Ad-IL-18BP/IL-4-BNL.CL2 were lower and IL-4 and IL-10 levels were higher than control groups. Phosphorylation levels of NF-κB p65, AKT, p38 and JNK1/2 in liver homogenates were markedly suppressed by Ad-IL-18BP/IL-4. Conclusions Ad-IL-18BP/IL-4 was effectively transfected into mouse BNL.CL2 cells. Intrasplenic transplantation of Ad-IL-18BP/IL-4-BNL.CL12 cells alleviated the severity of inflammation in ConA-induced experimental hepatitis and provides a useful basis for the targeted gene therapy of liver disease. PMID:23516562

Acceptance of background noise, working memory capacity, and auditory evoked potentials in subjects with normal hearing.

PubMed

Brännström, K Jonas; Zunic, Edita; Borovac, Aida; Ibertsson, Tina

2012-01-01

The acceptable noise level (ANL) test is a method for quantifying the amount of background noise that subjects accept when listening to speech. Large variations in ANL have been seen between normal-hearing subjects and between studies of normal-hearing subjects, but few explanatory variables have been identified. To explore a possible relationship between a Swedish version of the ANL test, working memory capacity (WMC), and auditory evoked potentials (AEPs). ANL, WMC, and AEP were tested in a counterbalanced order across subjects. Twenty-one normal-hearing subjects participated in the study (14 females and 7 males; aged 20-39 yr with an average of 25.7 yr). Reported data consists of age, pure-tone average (PTA), most comfortable level (MCL), background noise level (BNL), ANL (i.e., MCL - BNL), AEP latencies, AEP amplitudes, and WMC. Spearman's rank correlation coefficient was calculated between the collected variables to investigate associations. A principal component analysis (PCA) with Varimax rotation was conducted on the collected variables to explore underlying factors and estimate interactions between the tested variables. Subjects were also pooled into two groups depending on their results on the WMC test, one group with a score lower than the average and one with a score higher than the average. Comparisons between these two groups were made using the Mann-Whitney U-test with Bonferroni correction for multiple comparisons. A negative association was found between ANL and WMC but not between AEP and ANL or WMC. Furthermore, ANL is derived from MCL and BNL, and a significant positive association was found between BNL and WMC. However, no significant associations were seen between AEP latencies and amplitudes and the demographic variables, MCL, and BNL. The PCA identified two underlying factors: One that contained MCL, BNL, ANL, and WMC and another that contained latency for wave Na and amplitudes for waves V and Na-Pa. Using the variables in the first factor, the findings were further explored by pooling the subjects into two groups according to their WMC (WMClow and WMChigh). It was found that the WMClow had significantly poorer BNL than the WMChigh. The findings suggest that there is a strong relationship between BNL and WMC, while the association between MCL, ANL, and WMC seems less clear-cut. American Academy of Audiology.

Electronic and Physical Characterization of Hydrothermally Grown Single Crystal ThO2

DTIC Science & Technology

2013-12-26

35 BNL Brookhaven National Laboratories . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 VBM valence band maximum...Newton’s method. As an example, EXAFS data from Brookhaven National Laboratories ( BNL ) is analyzed. The data is from a thin metal Cu foil. A reasonable

DOE Office of Scientific and Technical Information (OSTI.GOV)

BROOKHAVEN NATIONAL LABORTORY; PROJECT MANAGER BARBARA COX

Brookhaven National Laboratory (BNL) strives for excellence in both its science research and its facility operations. BNL manages its world-class scientific research with particular sensitivity to environmental and community issues through its internationally recognized Environmental Management System (EMS) and award-winning community relations program. The Site Environmental Report 2000 (SER) summarizes the status of the Laboratory's environmental programs and performance, including the steady progress towards cleaning up the Laboratory site and fully integrating environmental stewardship into all facets of BNL's mission. BNL's motto, ''Exploring Earth's Mysteries... Protecting its Future,'' describes how the Laboratory approaches its work, with balance between science andmore » the environment. One of the newest initiatives at the Laboratory, the Upton Ecological and Research Reserve, will permanently preserve 530 acres (212 hectares) of the Long Island Central Pine Barrens, a unique ecosystem of forests and wetlands. The Reserve sets aside 10% of BNL property for conservation and ecological research through a partnership between the U.S. Department of Energy (DOE) and the U.S. Fish and Wildlife Service. The Reserve provides habitat for approximately 27 endangered, threatened, or species of special concern, including the state-endangered eastern tiger salamander, state-threatened banded sunfish, and swamp darter, along with a number of other species found onsite, such as the wild turkey and red-tailed hawk.« less

Selective antiproliferative and apoptotic effects of flavonoids purified from Rhus verniciflua Stokes on normal versus transformed hepatic cell lines.

PubMed

Son, Young-Ok; Lee, Kyung-Yeol; Lee, Jeong-Chae; Jang, Hyon-Seok; Kim, Jong-Ghee; Jeon, Young-Mi; Jang, Yong-Suk

2005-01-15

Considerable attention is being concentrated on dietary flavonoids in developing novel cancer-preventive approaches due to their potential ability to induce selective apoptosis of cancer cells. In this study, we prepared a flavonoid-containing fraction from a crude acetone extract of Rhus verniciflua Stokes (RVS), traditionally used as a food additive and as an herbal medicine, and named RVS chloroform-methanol fraction (RCMF). We evaluated the effects of RCMF on proliferation and apoptosis using mouse embryonic primary hepatic cells (MPHC), embryonic normal hepatic cell line (BNL CL.2), and its SV40-mediated transformed cell line (BNL SV A.8). We also investigated the effects of RCMF on the antioxidant defense system in those cells. This study demonstrated that RCMF exhibited a selective growth inhibition and apoptosis induction on transformed cells. BNL SV A.8 cells were more sensitive to RCMF-mediated cytotoxicity than were MPHC or BNL CL.2. RCMF-mediated reduction of MnSOD activity and glutathione (GSH) content in BNL SV A.8 cells is thought to be associated with RCMF-induced apoptosis. Our findings suggest that RCMF is an agent which may be capable of inducing growth inhibition and apoptosis of hepatic tumor cells.

Environmental Survey preliminary report, Brookhaven National Laboratory, Upton, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-06-01

This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Brookhaven National Laboratory (BNL) conducted April 6 through 17, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with BNL. The Survey covers all environmental media and all areas of environmental regulation. Itmore » is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at BNL, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Oak Ridge National Laboratory. When completed, the results will be incorporated into the BNL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the BNL Survey. 80 refs., 24 figs., 48 tabs.« less

Highlights from BNL and RHIC 2015

NASA Astrophysics Data System (ADS)

Tannenbaum, M. J.

The following sections are included: * Introduction * News from BNL since ISSP2014 * RHIC Operations in 2015 and accelerator future plans * 10th Anniversary Celebration of the Perfect Liquid * RHIC Beam Energy Scan (BES) in search of a critical point-aided by Lattice QCD * References

Antitumor effects of interleukin-18 gene-modified hepatocyte cell line on implanted liver carcinoma.

PubMed

Leng, Jianhang; Zhang, Lihuang; Yao, Hangping; Cao, Xuetao

2003-10-01

To investigate the antitumor effects of intrasplenically transplanted interleukin-18 (IL-18) gene-modified hepatocytes on murine implanted liver carcinoma. Embryonic murine hepatocyte cell line (BNL-CL2) was transfected with a recombinant adenovirus encoding IL-18 and used as delivery cells for IL-18 gene transfer. Two cell lines, BNL-LacZ and BNL-CL2, were used as controls. One week after intrasplenic injection of C26 cells (colon carcinoma line), tumor-bearing syngeneic mice underwent the intrasplenic transplantation of IL-18 gene-modified hepatocyte cell line and were divided into treatment group (BNL IL-18) and control groups (BNL-LacZ and BNL-CL2). Two weeks later, the serum levels of IL-18, interferon-gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) and nitric oxide (NO) in the implanted liver carcinoma-bearing mice were assayed, the cytotoxicity of murine splenic cytotoxic T-lymphocytes (CTLs) was measured, and the morphology of the hepatic tumors was studied to evaluate the antitumor effects of the approach. In the treatment group, the serum levels of IL-18, IFN-gamma, TNF-alpha and NO increased significantly. The splenic CTL activity increased markedly (P < 0.01), accompanied by a substantial decrease in tumor volume and the percentage of tumor area and prolonged survival of liver carcinomo-being mice. In vivo IL-18 expression by ex vivo manipulated cells with IL-18 recombinant adenovirus is able to exert potent antitumor effects by inducing a predominantly T-cell-helper type 1 (Th1) immune response. Intrasplenic transplantation of adenovirus-mediated IL-18 gene-modified hepatocytes could be used as a targeting treatment for implanted liver carcinoma.

Benthic nepheloid layers in the Gulf of Maine and Alexandrium cyst inventories

PubMed Central

Pilskaln, C.H.; Hayashi, K.; Keafer, B.A.; Anderson, D.M.; McGillicuddy, D.J.

2014-01-01

Cysts residing in benthic nepheloid layers (BNLs) documented in the Gulf of Maine have been proposed as a possible source of inoculum for annual blooms of a toxic dinoflagellate in the region. Herein we present a spatially extensive data set of the distribution and thickness of benthic nepheloid layers in the Gulf of Maine and the abundance and inventories of suspended Alexandrium fundyense cysts within these near-bottom layers. BNLs are pervasive throughout the gulf and adjacent Bay of Fundy with maximum layer thicknesses of 50–60 m observed. Mean BNL thickness is 30 m in the eastern gulf and Bay of Fundy, and 20 m in the western gulf. Cyst densities in the near-bottom particle resuspension layers varied by three orders of magnitude across the gulf with maxima of 105 cysts m−3. An important interconnection of elevated BNL cyst densities is observed between the Bay of Fundy, the Maine Coastal Current and the south-central region of the gulf. BNL cyst inventories estimated for the eastern and western gulf are each on the order of 1015 cysts, whereas the BNL inventory in the Bay of Fundy is on the order of 1016 . Although BNL cyst inventories in the eastern and western gulf are 1–2 orders of magnitude smaller than the abundance of cysts in the upper 1 cm of sediment in those regions, BNL and sediment-bound cyst inventories are comparable in the Bay of Fundy. The existence of widespread BNLs containing substantial cyst inventories indicates that these near-bottom layers represent an important source of germinating A. fundyense cysts in the region. PMID:25419055

[Effects of intrasplenic transplantation of IL-18 gene-modified fetal hepatocytes on mouse immune function

PubMed

Yao, Hang-Ping; Zhang, Li-Huang; Sun, Wen-Ji; Leng, Jian-Hang

2002-04-01

OBJECTIVE: To investigate the effects of IL-18 gene-modified fetal hepatocytes (AdmIL-18/MNL.CL2) intrasplenic transplantation on mouse immune function. METHODS: Forty mice were evenly divided into 4 groups of 10. Each group received an intrasplenic transplantation one of the following: AdmIL-18/BNL.CL2, Ad-LacZ/BNL.CL2 (virus control), BNL.CL2 (cell control) and PBS (blank control). After two weeks, the mice were sacrificed. Serum cytokine levels, Mpsi and splenic cell culture supernatant and liver tissue extracts supernatants were measured using ELISA. Hepatic cytokines mRNA expression were determined by RT-PCR. THe cytotoxicity of peritoneal Mpsi and NK activity of spienocytes were detected by LDH release assay. The proliferation of splenic lymphocytes was determined by MTT assay. RESULTS: The IL-18, IL-2,IFN-gamma, TNF-alpha levels of serum, Mpsi and splenocyte culture supernatant, liver tissue extracts supernatants in mice transplanted with AdmIL-18/BNL.CL2 were higher and the IL-4, IL-10 levels were lower compared to their levels in other 3 groups. The highest IL-18, IL-2, IFN-gamma, TNF-alpha and the lowest IL-4, IL-10 mRNA expressions in the liver were observed in mice transplanted with AdmIL-18/BNL.CL2. The mice transplanted with AdmIL-18/BNL.Cl2 showed significantly increases cytotoxicity of Mpsi, NK activity and splenic cell proliferation compared with the other 3 groups. CONCLUSION: AdmIL-18 can be effectively transfected into mice fetal heptocytes which subsequently IL-18. Intransplenic transplantation of IL-18 gene-modified fetal hepatocytes may augment mouse immune function and provide an useful basis for targeted gene therapy of liver disease.

Benthic nepheloid layers in the Gulf of Maine and Alexandrium cyst inventories.

PubMed

Pilskaln, C H; Hayashi, K; Keafer, B A; Anderson, D M; McGillicuddy, D J

2014-05-01

Cysts residing in benthic nepheloid layers (BNLs) documented in the Gulf of Maine have been proposed as a possible source of inoculum for annual blooms of a toxic dinoflagellate in the region. Herein we present a spatially extensive data set of the distribution and thickness of benthic nepheloid layers in the Gulf of Maine and the abundance and inventories of suspended Alexandrium fundyense cysts within these near-bottom layers. BNLs are pervasive throughout the gulf and adjacent Bay of Fundy with maximum layer thicknesses of 50-60 m observed. Mean BNL thickness is 30 m in the eastern gulf and Bay of Fundy, and 20 m in the western gulf. Cyst densities in the near-bottom particle resuspension layers varied by three orders of magnitude across the gulf with maxima of 10 5 cysts m -3 . An important interconnection of elevated BNL cyst densities is observed between the Bay of Fundy, the Maine Coastal Current and the south-central region of the gulf. BNL cyst inventories estimated for the eastern and western gulf are each on the order of 10 15 cysts, whereas the BNL inventory in the Bay of Fundy is on the order of 10 16 . Although BNL cyst inventories in the eastern and western gulf are 1-2 orders of magnitude smaller than the abundance of cysts in the upper 1 cm of sediment in those regions, BNL and sediment-bound cyst inventories are comparable in the Bay of Fundy. The existence of widespread BNLs containing substantial cyst inventories indicates that these near-bottom layers represent an important source of germinating A. fundyense cysts in the region.

Influence of Ionization and Beam Quality on Interaction of TW-Peak CO2 Laser with Hydrogen Plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samulyak, Roman

3D numerical simulations of the interaction of a powerful CO2 laser with hydrogen jets demonstrating the role of ionization and laser beam quality are presented. Simulations are performed in support of the plasma wakefield accelerator experiments being conducted at the BNL Accelerator Test Facility (ATF). The CO2 laser at BNL ATF has several potential advantages for laser wakefield acceleration compared to widely used solid-state lasers. SPACE, a parallel relativistic Particle-in-Cell code, developed at SBU and BNL, has been used in these studies. A novelty of the code is its set of efficient atomic physics algorithms that compute ionization and recombinationmore » rates on the grid and transfer them to particles. The primary goal of the initial BNL experiments was to characterize the plasma density by measuring the sidebands in the spectrum of the probe laser. Simulations, that resolve hydrogen ionization and laser spectra, help explain several trends that were observed in the experiments.« less

Evaluation of processes occurring in the bottom nepheloid layer (BNL) of an eastern Mediterranean area using 234Th/238U disequilibria.

PubMed

Evangeliou, Nikolaos; Florou, Heleny

2013-09-01

Particle-reactive radionuclide (234)Th and its ratios with the conservative (238)U were used to trace the marine processes occurring over short timescales in the bottom nepheloid layer (BNL) of seven stations in the Saronikos Gulf and the Elefsis Bay (Greece) during three seasons (summer 2008, autumn 2008 and winter 2009). Summer was considered as a steady season where low physical processes occur and stratification is well established, autumn as a commutative period and winter as period of extensive trawling and physical activities. The obtained ratio profiles showed excess of (234)Th relative to (238)U in the BNL of the sampling area during summer, caused by the dissolved fraction of (234)Th. During autumn, the situation was different with large (234)Th deficit throughout the water column leading to large export fluxes of particles from the water column. Finally, during winter the ratios showed that predominant phenomenon in the area was likely resuspension of bottom sediments. The resuspension signature was additionally evaluated by total suspended matter (TSM) inventories in the BNL. Despite the intense resuspension, small scavenging of dissolved (234)Th was recorded in the BNL resulting in high residence times of dissolved (234)Th. A 1 order of magnitude difference between dissolved and particulate (234)Th residence times was observed indicating that scavenging from dissolved to particulate (234)Th could be highly variable and, as a result, the Saronikos Gulf is a highly dynamic environment, in terms of temporal and spatial particle uptake and removal. Comparing these values to literature ones consistent results were obtained. The possibility of sediment resuspension in the BNL during winter was amplified by the bloom of phytoplankton resulting in even decreased residence times of particulate (234)Th (average values). In contrast, the respective residence times of the dissolved fraction of (234)Th in the BNL were higher showing a maximum in winter at the stations where resuspension concluded. Nevertheless, (234)Th cycling in the area is not controlled by TSM, probably due to the presence of colloids, which could play an essential role in (234)Th scavenging.

Proposal for Research on High-Brightness Cathodes for High-Power Free-Electron Lasers (FEL)

DTIC Science & Technology

2013-05-09

recent experiments involving single crystal diamond amplifier cathodes (DAC) at Brookhaven National Laboratory ( BNL ). While the emission surface of our...diamond grain in the entire structure, both surface and interior, is passivated with hydrogen. The aforementioned studies at BNL found that

Compression and Associated Properties of Boron Carbide

DTIC Science & Technology

2008-12-01

of Brookhaven National Laboratory ( BNL ) with the light extracted from the x-ray source in a method previously described (Liu et al., 2002).. A...are sharper and more intense relative to as received material. ACKNOWLEDGMENTS Thanks are due to Dr. Jingzhu Hu and Dr. Zhenxian Liu of BNL

Transformation of Mouse Liver Cells by Methylcholanthrene Leads to Phenotypic Changes Associated with Epithelial-mesenchymal Transition.

PubMed

Oh, Jiyun; Kwak, Jae-Hwan; Kwon, Do-Young; Kim, A-Young; Oh, Dal-Seok; Je, Nam Kyung; Lee, Jaewon; Jung, Young-Suk

2014-12-01

Environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs) have been implicated in cancer development and progression. However, the effects of PAHs on carcinogenesis are still poorly understood. Here, we characterized a mouse cancer cell line BNL 1ME A. 7R.1 (1MEA) derived by transformation of non-tumorigenic liver cell line BNL CL.2 (BNL) using 3-methylcholanthrene (3MC), a carcinogenic PAH. RT-PCR and immunoblot analysis were used to determine the expression level of mRNA and proteins, respectively. To determine functionality, cell motility was assessed in vitro using a transwell migration assay. Both mRNA and protein levels of E-cadherin were significantly decreased in 1MEA cells in comparison with BNL cells. While the expression levels of mesenchymal markers and related transcription factors were enhanced in 1MEA cells, which could lead to increase in cell motility. Indeed, we found that 7-day exposure of BNL cells to 3-MC reduced the level of the adhesion molecule and epithelial marker Ecadherin and increased reciprocally the level of the mesenchymal marker vimentin in a dose-dependent manner. Taken together, these results indicate that the process of epithelial-mesenchymal transition (EMT) may be activated during premalignant transformation induced by 3-MC. A mechanism study to elucidate the relation between 3-MC exposure and EMT is underway in our laboratory.

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX,K.J.

Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually inmore » March, as required by DOE Order 4 1 3.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The LDRD Annual Report contains summaries of all research activities funded during Fiscal Year 2002. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, the LDRD activities have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums. All Fy 2002 projects are listed and tabulated in the Project Funding Table. Also included in this Annual Report in Appendix A is a summary of the proposed projects for FY 2003. The BNL LDRD budget authority by DOE in FY 2002 was $7 million. The actual allocation totaled $6.7 million. The following sections in this report contain the management processes, peer review, and the portfolio's relatedness to BNL's mission, initiatives and strategic plans. Also included is a metric of success indicators.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX,K.J.

Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually inmore » March, as required by DOE Order 41 3.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The LDRD Annual Report contains summaries of all research activities funded during Fiscal Year 2003. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, the LDRD activities have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums. All FY 2003 projects are listed and tabulated in the Project Funding Table. Also included in this Annual Report in Appendix A is a summary of the proposed projects for FY 2004. The BNL LDRD budget authority by DOE in FY 2003 was $8.5 million. The actual allocation totaled $7.8 million. The following sections in this report contain the management processes, peer review, and the portfolio's relatedness to BNL's mission, initiatives and strategic plans. Also included is a metric of success indicators.« less

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2004

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX,K.J.

Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $460 million. There are about 2,800 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually inmore » March, as required by DOE Order 4 13.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL. The LDRD Annual Report contains summaries of all research activities funded during Fiscal Year 2004. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, the LDRD activities have resulted in numerous publications in various professional and scientific journals and presentations at meetings and forums. All FY 2004 projects are listed and tabulated in the Project Funding Table. Also included in this Annual Report in Appendix A is a summary of the proposed projects for FY 2005. The BNL LDRD budget authority by DOE in FY 2004 was $9.5 million. The actual allocation totaled $8.5 million. The following sections in this report contain the management processes, peer review, and the portfolio's relatedness to BNL's mission, initiatives and strategic plans. Also included is a metric of success indicators and Self Assessment.« less

Investigation on Novel Methods to Increase Specific Thrust in Pulse Detonation Engines via Imploding Detonations

DTIC Science & Technology

2009-12-01

Malliakos. Detonation cell size measurements in high-temperature hydrogen- air-steam mixtures at the bnl high-temperature combustion facility. Technical...Report NUREG/CR-6391, BNL -NUREG-52482, Brookhaven National Laboratory, 1997. [13] W.B. Benedick, R. Knystautas, and J.H.S. Lee. Large-scale

The Effect of Anisotropic Scatter on Atmospheric Neutron Transport

DTIC Science & Technology

2015-03-26

Labratory, ENDF-6 Formats Manual: Data Formats and Procedures for the Evaluated Nuclear Data Files ENDF/B-VI and ENDF/B-VII. BNL - 90365-2009, Revision 2...Upton, NY: BNL , December 2011 [7] Microsoft Visual Studio Professional 2013, Version 12.0.30501.00 Update 2. Computer Software. Microsoft Corporation

431st Brookhaven Lecture. Recombinant Science: The Birth of RHIC, A Drama of Three Acts

ScienceCinema

Crease, Robert

2017-12-22

Crease presents "Recombinant Science: The Birth of the Relativistic Heavy Ion Collider," a lecture that follows on the 429th Brookhaven Lecture, in which Crease talked about the early history of BNL. Both lectures are part of the ongoing celebration of BNL's 60th anniversary year.

LDRD 2017 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Jack; Flynn, Liz

This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2017, as required. In FY 2017, the BNL LDRD Program funded 46 projects, 13 of which were new starts, at a total cost of $10.4M.

Multipacting-free quarter-wavelength choke joint design for BNL SRF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, W.; Belomestnykh, S.; Ben-Zvi, I.

The BNL SRF gun cavity operated well in CW mode up to 2 MV. However, its performance suffered due to multipacting in the quarter-wavelength choke joint. A new multipacting-free cathode stalk was designed and conditioned. This paper describes RF and thermal design of the new cathode stalk and its conditioning results.

Quantum Efficiency as a Function of Temperature in Metal Photocathodes

DTIC Science & Technology

2013-06-01

Srinivasan-Rao, I. Ben-Zvi, A. Burrill, H. Hahn, D. Kayran, Y. Zhao, and M. Cole. “Photoemission studies on BNL /AES/JLAB all niobium, superconducting RF...Hershcovitch, D. Pate, A. Reuter et al., “Design, construction and status of all niobium superconducting photoinjector at BNL ,” Proc. IEEE of the

2013 BNL Site Environmental Report. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ratel, K.; Remien, J.; Pohlot, P.

A summary of Brookhaven National Laboratory’s (BNL) Site Environmental Report, meant to inform the public, regulators, employees, and other stakeholders of the Laboratory’s environmental performance in the lab’s surrounding area during the calendar year. The review is comprised of multiple volumes relevant to environmental data/environmental management performance and groundwater status report.

Laboratory Directed Research and Development Program Assessment for FY 2015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, Diane; Barkigia, K.; Giacalone, P.

2016-03-01

This report provides an overview of the BNL LDRD program and a summary of the management processes, project peer review, a financial overview, and the relation of the portfolio of LDRD projects to BNL's mission, initiatives, and strategic plan. Also included are a summary of success indicators and a self-assessment.

QUARKONIUM PRODUCTION IN RELATIVISTIC NUCLEAR COLLISIONS. PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 12

DOE Office of Scientific and Technical Information (OSTI.GOV)

KHARZEEV,D.

1999-04-20

The RIKEN-BNL Workshop on Quarkonium Production in Relativistic Nuclear Collisions was held September 28--October 2, 1998, at Brookhaven National Laboratory. The Workshop brought together about 50 invited participants from around the world and a number of Brookhaven physicists from both particle and nuclear physics communities.

LPS induces direct death of IFN-gamma primed murine embryonic hepatocyte, BNL CL2 cells in a TNF-alpha independent manner.

PubMed

So, H S; Jung, B H; Yeum, S S; Park, J S; Kim, M S; Lee, J H; Chung, S Y; Choi, S; Chae, H J; Kim, H R; Ko, C B; Chung, H T; Park, R

2000-11-01

Although it has been well known that the role of LPS on liver damage is mediated through TNF-alpha, the mechanism by which LPS modulates the cytotoxicity of IFN-gamma on hepatocytes has not yet been clearly demonstrated. Here, we demonstrate that IFN-gamma mediated apoptosis in murine embryonic hepatocyte BNL CL2 cells is potentiated by the addition of LPS (0.5 microg/ml). Consistently, LPS markedly increases the catalytic activity of caspase 3-like protease but not caspase 1-like protease in IFN-gamma treated cells. In addition, TNF-alpha alone does not affect cell viability but rather it potentiates the cytotoxic effect of IFN-gamma on BNL CL2 cells. However, the cell viability of IFN-gamma/LPS treated cells is affected by the addition of polymyxin B but not by TNF binding protein I (TNF-BPI). These data suggest that the lipid moiety of LPS may mediate direct cytotoxicity of BNL CL2 cells in a TNF-alpha independent manner.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brookhaven National Laboratory

Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inceptionmore » in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in this volume in Chapter 7, Groundwater Protection. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the full report.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ratel,K.

Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inceptionmore » in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in this volume in Chapter 7, Groundwater Protection. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the-length report.« less

Synergistic regulation of the acute phase protein SIP24/24p3 by glucocorticoid and pro-inflammatory cytokines.

PubMed

Liu, Quan-Sheng; Nilsen-Hamilton, Marit; Xiong, Si-Dong

2003-10-25

SIP24/24p3 is a secreted murine acute phase protein which has been speculated to play an anti-inflammatory role in vivo. Recently SIP24/24p3 has been found to be able to specifically induce apoptosis in leukocytes. By using (35)S metabolic labeling method, we studied the regulation of SIP24/24p3 by glucocorticoid and pro-inflammatory cytokines IL-6 and TNF-alpha in cultured Balb/c 3T3 and BNL cells. The following results were observed: (1) dexamethasone induced the expression of SIP24/24p3 in both Balb/c 3T3 and BNL cells, the induction was more significant in BNL cells; (2) dexamethasone and IL-6 synergistically induced the expression of SIP24/24p3 in both Balb/c 3T3 and BNL cells; (3) in Balb/c 3T3 cells dexamethasone and TNF-alpha acted synergistically to induce the expression of SIP24/24p3, whereas in BNL cells dexamethasone and TNF-alpha induced the expression of SIP24/24p3 in an additive manner; (4) dexamethasone and IL-6/TNF-alpha acted synergistically in Balb/c 3T3 cells and additively in BNL cells to induce the expression of SIP24/24p3. The inducibility of SIP24/24p3 by multiple factors will help to explain its highly specific expression in vivo. The difference in the expression patterns of SIP24/24p3 in different cell types is also suggestive to its expression and regulation in hepatic and extrahepatic tissues. Finally, the fact that SIP24/24p3 protein can be induced by both pro-inflammatory as well as anti-inflammatory factors is indicative of the important role of SIP24/24p3 in the entire acute phase response process.

Spatial and temporal variability of Alexandrium cyst fluxes in the Gulf of Maine: Relationship to seasonal particle export and resuspension.

PubMed

Pilskaln, C H; Anderson, D M; McGillicuddy, D J; Keafer, B A; Hayashi, K; Norton, K

2014-05-01

Quantification of Alexandrium cyst fluxes through the Gulf of Maine water column is central to understanding the linkage between the source and fate of annual Alexandrium blooms in the offshore waters. These blooms often lead to paralytic shellfish poisoning (PSP) and extensive closures of shellfish beds. We report here on time-series sediment trap deployments completed at four offshore locations in the gulf between 2005 and 2010 as components of two ECOHAB-GOM field programs. Data presented documents the substantial spatial and temporal fluctuations in Alexandrium fundyense cyst fluxes in the gulf. Cyst delivery out of the euphotic zone peaked primarily between July and August following annual spring-summer Alexandrium blooms and was greatest in the western gulf. At all sites, cyst flux maxima to the subsurface waters were rarely coincident with seasonal peaks in the total mass export of particulate material indicating that cyst delivery was primarily via individually sinking cysts. Where persistent benthic nepheloid layers (BNLs) exist, significant sediment resuspension input of cysts to the near-bottom water column was evidenced by deep cyst fluxes that were up to several orders of magnitude greater than that measured above the BNL. The largest cyst fluxes in the BNL were observed in the eastern gulf, suggesting greater resuspension energy and BNL cyst inventories in this region. Temporal similarities between peak cyst export out of the upper ocean and peak cyst fluxes in the BNL were observed and document the contribution of seasonal, newly formed cysts to the BNL. The data however also suggest that many Alexandrium cells comprising the massive, short-lived blooms do not transition into cysts. Time-series flow measurements and a simple 1D model demonstrate that the BNL cyst fluxes reflect the combined effects of tidal energy-maintained resuspension, deposition, and input of cysts from the overlying water column.

Spatial and temporal variability of Alexandrium cyst fluxes in the Gulf of Maine: Relationship to seasonal particle export and resuspension

PubMed Central

Pilskaln, C.H.; Anderson, D.M.; McGillicuddy, D.J.; Keafer, B.A.; Hayashi, K.; Norton, K.

2014-01-01

Quantification of Alexandrium cyst fluxes through the Gulf of Maine water column is central to understanding the linkage between the source and fate of annual Alexandrium blooms in the offshore waters. These blooms often lead to paralytic shellfish poisoning (PSP) and extensive closures of shellfish beds. We report here on time-series sediment trap deployments completed at four offshore locations in the gulf between 2005 and 2010 as components of two ECOHAB–GOM field programs. Data presented documents the substantial spatial and temporal fluctuations in Alexandrium fundyense cyst fluxes in the gulf. Cyst delivery out of the euphotic zone peaked primarily between July and August following annual spring–summer Alexandrium blooms and was greatest in the western gulf. At all sites, cyst flux maxima to the subsurface waters were rarely coincident with seasonal peaks in the total mass export of particulate material indicating that cyst delivery was primarily via individually sinking cysts. Where persistent benthic nepheloid layers (BNLs) exist, significant sediment resuspension input of cysts to the near-bottom water column was evidenced by deep cyst fluxes that were up to several orders of magnitude greater than that measured above the BNL. The largest cyst fluxes in the BNL were observed in the eastern gulf, suggesting greater resuspension energy and BNL cyst inventories in this region. Temporal similarities between peak cyst export out of the upper ocean and peak cyst fluxes in the BNL were observed and document the contribution of seasonal, newly formed cysts to the BNL. The data however also suggest that many Alexandrium cells comprising the massive, short-lived blooms do not transition into cysts. Time-series flow measurements and a simple 1D model demonstrate that the BNL cyst fluxes reflect the combined effects of tidal energy-maintained resuspension, deposition, and input of cysts from the overlying water column. PMID:25431527

Tribochemical Studies of Hard Carbon Films as a Function of Load and Environment

DTIC Science & Technology

2010-08-13

the wear tracks on the flat as well as the wear scar on the sphere. The BNL imaging apparatus uses a magnetic field to guide the photoemitted...from the sample surface, and the electron optics, which can filter electrons with the wrong path or energy. The BNL imaging chamber is not able to

Twenty years of space radiation physics at the BNL AGS and NASA Space Radiation Laboratory.

PubMed

Miller, J; Zeitlin, C

2016-06-01

Highly ionizing atomic nuclei HZE in the GCR will be a significant source of radiation exposure for humans on extended missions outside low Earth orbit. Accelerators such as the LBNL Bevalac and the BNL AGS, designed decades ago for fundamental nuclear and particle physics research, subsequently found use as sources of GCR-like particles for ground-based physics and biology research relevant to space flight. The NASA Space Radiation Laboratory at BNL was constructed specifically for space radiation research. Here we review some of the space-related physics results obtained over the first 20 years of NASA-sponsored research at Brookhaven. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

MAGNET ENGINEERING AND TEST RESULTS OF THE HIGH FIELD MAGNET R AND D PROGRAM AT BNL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

COZZOLINO,J.; ANERELLA,M.; ESCALLIER,J.

2002-08-04

The Superconducting Magnet Division at Brookhaven National Laboratory (BNL) has been carrying out design, engineering, and technology development of high performance magnets for future accelerators. High Temperature Superconductors (HTS) play a major role in the BNL vision of a few high performance interaction region (IR) magnets that would be placed in a machine about ten years from now. This paper presents the engineering design of a ''react and wind'' Nb{sub 3}Sn magnet that will provide a 12 Tesla background field on HTS coils. In addition, the coil production tooling as well as the most recent 10-turn R&D coil test resultsmore » will be discussed.« less

Nitric oxide protects murine embryonic liver cells (BNL CL.2) from cytotoxicity induced by glucose deprivation.

PubMed

Pae, H O; Kim, H G; Paik, Y S; Paik, S G; Kim, Y M; Oh, G S; Chung, H T

2000-03-01

We investigated the protective effects of nitric oxide on cell death of murine embryonic liver cells (BNL CL.2) after glucose deprivation. Endogenous nitric oxide production by BNL CL.2 cells was induced by 6 hr pretreatment with interferon-gamma and lipopolysaccharide. We used sodium nitroprusside and S-nitroso-L-glutathione as exogenous nitric oxide-generating compounds. All agents were used at doses that did not show direct cytotoxicity as measured by crystal violet staining assay. In the BNL CL.2 cells, the viability dropped very steeply after 24 hr incubation with glucose-free media. Endogenous nitric oxide produced by treatment of the cells with interferon-gamma and lipopolysaccharide protected the cells from glucose deprivation-induced cytotoxicity, but did not protect them in the presence of the nitric oxide synthesis inhibitor, N(G)-monomethyl-L-arginine. Exogenous nitric oxide protected the cells from glucose deprivation-induced cytotoxicity in a concentration-dependent manner. Cytoprotection by nitric oxide donors was abolished by the use of nitric oxide scavenger, 2-phenyl-4,4,5,5,-tetramethylimidazole, but not by the soluble guanosine cyclase inhibitor, 1H-[1,2,4]oxadiazole[4,3-a]quinoxalin-1-one. In addition, cytoprotective effects comparable to endogenous or exogenous nitric oxide were not observed when the cells were incubated with dibutyl guanosine 3',5'-cyclic monophosphate. Based upon these results, we suggest that nitric oxide may enhance the cell survival of BNL CL.2 cells after glucose deprivation via a guanosine 3',5'-cyclic monophosphate-independent pathway.

Highlights from BNL and RHIC 2014

NASA Astrophysics Data System (ADS)

Tannenbaum, M. J.

The following sections are included: * Introduction * News from BNL since ISSP2013 * RHIC Operations and accelerator future plans * Detector issues in A+A compared to p+p collisions * Nch, ET distributions and constituent-quarks as the fundamental elements of particle production * Collective Flow * RHIC Beam Energy Scan (BES)-in search of the critical point * Jet quenching, RHIC's main claim to fame * References

Tabulated dose uniformity ratio and minimum dose data: rectangular 60Co source plaques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galanter, L.

1971-01-01

The data tabulated herein extend to rectangular cobalt-60 plaques the information presented for square plaques in BNL 50145 (Revised). The user is referred to BNL 50145 (Revised) and to the other reports listed for a complete discussion of the parameters involved in data generation and for instructions on the use of these data in gamma irradiator design.

Comparison of telomere length and telomerase activation between breast fibroadenoma and infiltrating ductal carcinoma in Malaysian women.

PubMed

Looi, Lai-Meng; Cheah, Phaik-Leng; Ng, Min-Hwei; Yip, Cheng-Har; Mun, Kein-Seong; Rahman, Nazarina Abdul

2010-01-01

A study was initiated to explore possible differences in handling telomere attrition in the most common lignant and benign tumours of the breast in Malaysian women. Infiltrating ductal carcinoma (IDC) and fibroadenoma (FA) represented the malignant and benign prototypes respectively. 29 IDC, 28 FA and 22 benign non-lesional control (BNL) breast tissue samples were analysed for telomerase activation using a Telomerase PCR ELISA kit (Boehringer Mannheim). In addition, 23 IDC, 12 FA and 14 BNL were subjected to telomere length determination with a TeloTAGGG Telomere Length Assay Kit (Roche Diagnostic GmbH, Germany), following digestion of genomic DNA by frequently cutting restriction enzymes RsaI and HinfI. Mean telomerase activity in IDC (A450nm=0.3338), but not FA (A450nm=0.0003) was significantly raised (p<0.05) compared with BNL (A450nm=0.0031). Similarly IDC (1.2 kb), but not FA (2.2 kb), showed significant telomere shortening (p<0.05) relative to BNL (2.9 kb). The findings imply that telomere attrition and telomerase activation differ between malignant and benign tumours of the breast and may be important for targeted therapy.

Stratigraphy and hydrologic conditions at the Brookhaven National Laboratory and vicinity, Suffolk County, New York, 1994-97

USGS Publications Warehouse

Scorca, Michael P.; Dorsch, William R.; Paquette, Douglas E.

1999-01-01

Brookhaven National Laboratory (BNL) has installed many test borings as part of an effort to delineate the extent of ground-water contamination at the site. In 1994, the U.S. Geological Survey began a study in cooperation with BNL to define the stratigraphy in the 28-square-mile area encompassing BNL, and to monitor ground-water levels in the 300 squaremile area of central Suffolk County that surrounds BNL. The uppermost geologic units at BNL are of Pleistocene age. These sediments are underlain unconformably by the Matawan Group-Magothy Formation, undifferentiated (referred to as the Magothy Formation), of Cretaceous age, which typically consists of light- to dark-gray, variably sorted sand interbedded with light- to dark-gray clay layers; it also contains beds of grayish-brown to brownish-gray sand. Bed thicknesses differ substantially within each boring and tend to be laterally discontinuous as a result of their terrestrial deltaic depositional environment, although a prominent clay unit, referred to as the ?grayish-brown clay? in this report, was encountered at many borings. Pollen-sample analyses confirm that this unit is of Cretaceous age and is the uppermost unit of Cretaceous sediments in several parts of the study area. The upper surface of the Cretaceous deposits is irregular within the 28-square-mile study area and has relief of about 120 feet. Several prominent channels and ridges in the surface are aligned generally northwest-southeast. The Cretaceous surface beneath BNL is characterized more by local erosional features than by the regional cuesta shape that was suggested by previous authors. The overlying Pleistocene-aged units include (1) a sand layer overlain by the Gardiners Clay, (2) the Gardiners Clay, and (3) upper Pleistocene deposits, which include the Upton unit, glacial outwash, glaciolacustrine deposits, and terminal moraine deposits. The sand unit below the Gardiners Clay was the first Pleistocene unit to be deposited atop the irregular surface of the Cretaceous deposits in this area. The Gardiners Clay was deposited during a major rise in sea level as the sea encroached into parts of the present-day BNL study area. The shallow part of the upper Pleistocene deposits generally consists of light-brown sand and gravel but overlies green to grayish-green, variably sorted sand, silt, and clay at altitudes of 50 to 70 feet below sea level in some parts of the study area. This lower part of the upper Pleistocene deposits in the study area was referred to by previous investigators as the unidentified unit and has been designated as the Upton unit in this report. The discharge of ground water to the Peconic and Carmans Rivers locally affects the water-table configuration. The main ground-water divide on Long Island is about 0.5 miles north of the site; a secondary divide originates near the start of flow of the Peconic River and extends east-southeastward toward the South Fork. The water-table configuration on the BNL site is affected by pumping from supply wells and remediation wells, by infiltration of the water through recharge basins, by discharge from the sewage-treatment plant, and by local near-surface clay units. The horizontal hydraulic gradient at BNL typically is 0.001 foot per foot but can steepen near recharge basins and pumping wells. Vertical flow gradients within the upper Pleistocene deposits (upper glacial aquifer) were as large as 0.007 foot per foot (downward) in the northern part of BNL and were negligible in the southern part. Downward vertical gradients between the lower part of the upper glacial aquifer and the upper part of the Magothy Formation (Magothy aquifer) were about 0.018 foot per foot throughout the site.

Integrative Curriculum Development in Nuclear Education and Research Vertical Enhancement Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Egarievwe, Stephen U.; Jow, Julius O.; Edwards, Matthew E.

Using a vertical education enhancement model, a Nuclear Education and Research Vertical Enhancement (NERVE) program was developed. The NERVE program is aimed at developing nuclear engineering education and research to 1) enhance skilled workforce development in disciplines relevant to nuclear power, national security and medical physics, and 2) increase the number of students and faculty from underrepresented groups (women and minorities) in fields related to the nuclear industry. The program uses multi-track training activities that vertically cut across the several education domains: undergraduate degree programs, graduate schools, and post-doctoral training. In this paper, we present the results of an integrativemore » curriculum development in the NERVE program. The curriculum development began with nuclear content infusion into existing science, engineering and technology courses. The second step involved the development of nuclear engineering courses: 1) Introduction to Nuclear Engineering, 2) Nuclear Engineering I, and 2) Nuclear Engineering II. The third step is the establishment of nuclear engineering concentrations in two engineering degree programs: 1) electrical engineering, and 2) mechanical engineering. A major outcome of the NERVE program is a collaborative infrastructure that uses laboratory work, internships at nuclear facilities, on-campus research, and mentoring in collaboration with industry and government partners to provide hands-on training for students. The major activities of the research and education collaborations include: - One-week spring training workshop at Brookhaven National Laboratory: The one-week training and workshop is used to enhance research collaborations and train faculty and students on user facilities/equipment at Brookhaven National Laboratory, and for summer research internships. Participants included students, faculty members at Alabama A and M University and research collaborators at BNL. The activities include 1) tour and introduction to user facilities/equipment at BNL that are used for research in room-temperature semiconductor nuclear detectors, 2) presentations on advances on this project and on wide band-gap semiconductor nuclear detectors in general, and 3) graduate students' research presentations. - Invited speakers and lectures: This brings collaborating research scientist from BNL to give talks and lectures on topics directly related to the project. Attendance includes faculty members, researchers and students throughout the university. - Faculty-students team summer research at BNL: This DOE and National Science Foundation (NSF) program help train students and faculty members in research. Faculty members go on to establish research collaborations with scientists at BNL, develop and submit research proposals to funding agencies, transform research experience at BNL to establish and enhance reach capabilities at home institution, and integrate their research into teaching through class projects and hands-on training for students. The students go on to participate in research work at BNL and at home institution, co-author research papers for conferences and technical journals, and transform their experiences into developing senior and capstone projects. - Grant proposal development: Faculty members in the NERVE program collaborate with BNL scientists to develop proposals, which often help to get external funding needed to expand and sustain the continuity of research activities and supports for student's wages and scholarships (stipends, tuition and fees). - Faculty development and mentoring: The above collaboration activities help faculty professional development. The experiences, grants, joint publications in technical journals, and supervision of student's research, including thesis and dissertation research projects, contribute greatly to faculty development. Senior scientists at BNL and senior faculty members on campus jointly mentor junior faculty members to enhance their professional growth. - Graduate thesis and dissertation research: Brookhaven National Laboratory provides unique opportunities and outstanding research resources for the NERVE program graduate research. Scientists from BNL serve in master's degree thesis and PhD dissertation committees, where they play active roles in the supervision of the research. (authors)« less

Meteorological services annual data report for 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heiser, John

This document presents the meteorological data collected at Brookhaven National Laboratory (BNL) by Meteorological Services (Met Services) for the calendar year 2017. The purpose is to publicize the data sets available to emergency personnel, researchers and facility operations. Met services has been collecting data at BNL since 1949. Data from 1994 to the present is available in digital format. Data is presented in monthly plots of one-minute data. This allows the reader the ability to peruse the data for trends or anomalies that may be of interest to them. Full data sets are available to BNL personnel and to amore » limited degree outside researchers. The full data sets allow plotting the data on expanded time scales to obtain greater details (e.g., daily solar variability, inversions, etc.).« less

Meteorological services annual data report for 2015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heiser, John; Smith, Scott

This document presents the meteorological data collected at Brookhaven National Laboratory (BNL) by Meteorological Services (Met Services) for the calendar year 2015. The purpose is to publicize the data sets available to emergency personnel, researchers and facility operations. Met services has been collecting data at BNL since 1949. Data from 1994 to the present is available in digital format. Data is presented in monthly plots of one-minute data. This allows the reader the ability to peruse the data for trends or anomalies that may be of interest to them. Full data sets are available to BNL personnel and to amore » limited degree outside researchers. The full data sets allow plotting the data on expanded time scales to obtain greater details (e.g., daily solar variability, inversions, etc.).« less

Meteorological services annual data report for 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heiser, John; Smith, S.

This document presents the meteorological data collected at Brookhaven National Laboratory (BNL) by Meteorological Services (Met Services) for the calendar year 2016. The purpose is to publicize the data sets available to emergency personnel, researchers and facility operations. Met services has been collecting data at BNL since 1949. Data from 1994 to the present is available in digital format. Data is presented in monthly plots of one-minute data. This allows the reader the ability to peruse the data for trends or anomalies that may be of interest to them. Full data sets are available to BNL personnel and to amore » limited degree outside researchers. The full data sets allow plotting the data on expanded time scales to obtain greater details (e.g., daily solar variability, inversions, etc.).« less

Chance Favors Only the Prepared Mind: The Proper Role for U.S. Department of Defense Science and Engineering Workforce

DTIC Science & Technology

2013-08-01

establishments staffed by private sector S&Es (Argonne National Laboratory (ANL), Brookhaven National Laboratory ( BNL ), Jet Propulsion Laboratory...21 Table 1 Academy ANL BNL JPL LANL LL LLNL NIH NIST NRL NAE 2 1 4 1 1 1 1 7 8 NAS 4 7 1 3 0 1 52 7 3 IOM 0 0 0 0

Pest resistance and agronomic performance of Upland cotton lines following eight generations of introgression of the BNL3279_105 DNA marker from Gossypium barbadense GB713

USDA-ARS?s Scientific Manuscript database

The BNL3279 primers give unique DNA markers that are closely linked with resistance to reniform nematodes in Gossypium longicalx, Gossypium barbadense GB713, and Gossypium aridum. Plants that had been selected and advanced based on reniform nematode bioassays for each of five or six generations of ...

Photocathodes for High Repetition Rate Light Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ben-Zvi, Ilan

2014-04-20

This proposal brought together teams at Brookhaven National Laboratory (BNL), Lawrence Berkeley National Laboratory (LBNL) and Stony Brook University (SBU) to study photocathodes for high repetition rate light sources such as Free Electron Lasers (FEL) and Energy Recovery Linacs (ERL). Below details the Principal Investigators and contact information. Each PI submits separately for a budget through his corresponding institute. The work done under this grant comprises a comprehensive program on critical aspects of the production of the electron beams needed for future user facilities. Our program pioneered in situ and in operando diagnostics for alkali antimonide growth. The focus ismore » on development of photocathodes for high repetition rate Free Electron Lasers (FELs) and Energy Recovery Linacs (ERLs), including testing SRF photoguns, both normal-­conducting and superconducting. Teams from BNL, LBNL and Stony Brook University (SBU) led this research, and coordinated their work over a range of topics. The work leveraged a robust infrastructure of existing facilities and the support was used for carrying out the research at these facilities. The program concentrated in three areas: a) Physics and chemistry of alkali-­antimonide cathodes (BNL – LBNL) b) Development and testing of a diamond amplifier for photocathodes (SBU -­ BNL) c) Tests of both cathodes in superconducting RF photoguns (SBU) and copper RF photoguns (LBNL) Our work made extensive use of synchrotron radiation materials science techniques, such as powder-­ and single-­crystal diffraction, x-­ray fluorescence, EXAFS and variable energy XPS. BNL and LBNL have many complementary facilities at the two light sources associated with these laboratories (NSLS and ALS, respectively); use of these will be a major thrust of our program and bring our understanding of these complex materials to a new level. In addition, CHESS at Cornell will be used to continue seamlessly throughout the NSLS dark period and new diffraction facilities at ALS will be utilized. We also will continue to make use of the excellent analytical facilities at the CNF (BNL) and the Molecular Foundry (LBNL), where we have access to state of the art UHV XPS, SPM, SEM and scanning Auger microscopy.« less

Measurements of charge state breeding efficiency at BNL test EBIS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kondrashev, S.; Alessi, J.; Beebe, E.N.

Charge breeding of singly charged ions is required to efficiently accelerate rare isotope ion beams for nuclear and astrophysics experiments, and to enhance the accuracy of low-energy Penning trap-assisted spectroscopy. An efficient charge breeder for the Californium Rare Isotope Breeder Upgrade (CARIBU) to the ANL Tandem Linear Accelerator System (ATLAS) facility is being developed using the BNL Test Electron Beam Ion Source (Test EBIS) as a prototype. Parameters of the CARIBU EBIS charge breeder are similar to those of the BNL Test EBIS except the electron beam current will be adjustable in the range from 1 to 2 {angstrom}. Themore » electron beam current density in the CARIBU EBIS trap will be significantly higher than in existing operational charge state breeders based on the EBIS concept. The charge state breeding efficiency is expected to be about 25% for the isotope ions extracted from the CARIBU. For the success of our EBIS project, it is essential to demonstrate high breeding efficiency at the BNL Test EBIS tuned to the regime close to the parameters of the CARIBU EBIS at ANL. The breeding efficiency optimization and measurements have been successfully carried out using a Cs{sup +} surface ionization ion source for externally pulsed injection into the BNL Test EBIS. A Cs{sup +} ion beam with a total number of ions of 5 x 10{sup 8} and optimized pulse length of 70 {mu}s has been injected into the Test EBIS and charge-bred for 5.3 ms for two different electron beam currents 1 and 1.5 {angstrom}. In these experiments we have achieved 70% injection/extraction efficiency and breeding efficiency into the most abundant charge state 17%.« less

NATURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

DOE Office of Scientific and Technical Information (OSTI.GOV)

GREEN,T.ET AL.

2003-12-31

Brookhaven National Laboratory (BNL) is located near the geographic center of Long Island, New York. The Laboratory is situated on 5,265 acres of land composed of Pine Barrens habitat with a central area developed for Laboratory work. In the mid-1990s BNL began developing a wildlife management program. This program was guided by the Wildlife Management Plan (WMP), which was reviewed and approved by various state and federal agencies in September 1999. The WMP primarily addressed concerns with the protection of New York State threatened, endangered, or species of concern, as well as deer populations, invasive species management, and the revegetationmore » of the area surrounding the Relativistic Heavy Ion Collider (RHIC). The WMP provided a strong and sound basis for wildlife management and established a basis for forward motion and the development of this document, the Natural Resource Management Plan (NRMP), which will guide the natural resource management program for BNL. The body of this plan establishes the management goals and actions necessary for managing the natural resources at BNL. The appendices provide specific management requirements for threatened and endangered amphibians and fish (Appendices A and B respectively), lists of actions in tabular format (Appendix C), and regulatory drivers for the Natural Resource Program (Appendix D). The purpose of the Natural Resource Management Plan is to provide management guidance, promote stewardship of the natural resources found at BNL, and to integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, adaptive ecosystem management, compliance, integration with other plans and requirements, and incorporation of community involvement, where applicable.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwager, K.; Green, T. M.

The DOE policy for managing wildland fires requires that all areas managed by DOE and/or Its various contractors which can sustain fire must have a FMP that details fire management guidelines for operational procedures associated with wildland fire, operational, and prescribed fires. FMPs provide guidance on fire preparedness, fire prevention, wildfire suppression, and the use of controlled ''prescribed'' fires and mechanical means to control the amount of available combustible material. Values reflected in the BNL Wildland FMP include protecting life and public safety; Lab properties, structures and improvements; cultural and historical sites; neighboring private and public properties; and endangered, threatened,more » and species of concern. Other values supported by the plan include the enhancement of fire-dependent ecosystems at BNL. The plan will be reviewed periodically to ensure fire program advances and will evolve with the missions of DOE and BNL.« less

Structural and Chemical Properties of the Nitrogen-Rich Energetic Material Triaminoguanidinium 1-methyl-5-nitriminotetrazolate under Pressure

DTIC Science & Technology

2012-08-01

Source (NSLS) of Brookhaven National Laboratory ( BNL ). The syn- chrotron light is extracted from the VUV storage ring in a 40 × 40 mrad solid angle and...Contract No. DE-AC02-06CH11357. Infrared mea- surements were performed at the U2A beamline at the NSLS of BNL (DOE Contract No. DE-AC02-98CH10886). The

ANNUAL REPORT, JULY 1, 1957

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1958-10-31

The progress and trends of research are presented along with a description of operational, service, end administrative activities. Some scientific and technical details are given on research programs in the physical sciences, life sciences, and engineering, however, more complete technical information is available in quarterly progress reports, BNL technical reports, and scientific and technical periodicals. A bibliography of these publications is appended. (For preceding period see BNL-426.) (D.E.B.)

DOE Office of Scientific and Technical Information (OSTI.GOV)

INSTRUMENTATION DIVISION STAFF

To develop state-of-the-art instrumentation required for experimental research programs at BNL, and to maintain the expertise and facilities in specialized high technology areas essential for this work. Development of facilities is motivated by present BNL research programs and anticipated future directions of BNL research. The Division's research efforts also have a significant impact on programs throughout the world that rely on state-of-the-art radiation detectors and readout electronics. Our staff scientists are encouraged to: Become involved in challenging problems in collaborations with other scientists; Offer unique expertise in solving problems; and Develop new devices and instruments when not commercially available. Scientistsmore » from other BNL Departments are encouraged to bring problems and ideas directly to the Division staff members with the appropriate expertise. Division staff is encouraged to become involved with research problems in other Departments to advance the application of new ideas in instrumentation. The Division Head integrates these efforts when they evolve into larger projects, within available staff and budget resources, and defines the priorities and direction with concurrence of appropriate Laboratory program leaders. The Division Head also ensures that these efforts are accompanied by strict adherence to all ES and H regulatory mandates and policies of the Laboratory. The responsibility for safety and environmental protection is integrated with supervision of particular facilities and conduct of operations.« less

Wildland Fire Management Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwager, K.

The Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) is written to comply with Department of Energy (DOE) Integrated Safety Management Policy; Federal Wildland Fire Management Policy and Program Review; and Wildland and Prescribed Fire Management Policy and Implementation Procedures Reference Guide. This current plan incorporates changes resulting from new policies on the national level as well as significant changes to available resources and other emerging issues, and replaces BNL's Wildland FMP dated 2014.

NATO Glossary of Abbreviations Used in NATO Documents and Publications (glossaire otan des abreviations utilisees dans les documents et publications otan)

DTIC Science & Technology

2010-01-01

télévision à bas niveau de lumière /TV BNL / [NASG] LMCC LOCE mobile communications centre [NASG] centre de communications mobile du LOCE [NASG...AC/224] équipe de soutien technique [STANAG 4607] T-12 AAP-15(2010) TV BNL TTBT télévision à bas niveau de lumière Threshold Test-Ban

PHENIX Spinfest School 2009 at BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foster,S.P.; Foster,S.; Seidl, R.

2009-08-07

Since 2005, the PHENIX Spin Physics Working Group has set aside several weeks each summer for the purposes of training and integrating recent members of the working group as well as coordinating and making rapid progress on support tasks and data analysis. One week is dedicated to more formal didactic lectures by outside speakers. The location has so far alternated between BNL and the RIKEN campus in Wako, Japan, with support provided by RBRC and LANL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

BROOKHAVEN NATIONAL LABORATORY

The 2002 Site Environmental Report (SER) is prepared in accordance with DOE Order 231.1, ''Environment, Safety and Health Reporting'', and summarizes the status of Brookhaven National Laboratory's (BNL) environmental programs and performance and restoration efforts, as well as any impacts, both past and present, that Laboratory operations have had on the environment. The document is intended to be technical in nature. A summary of the report is also prepared as a separate document to provide a general overview and includes a CD version of the full report. Operated by Brookhaven Science Associates (BSA) for the Department of Energy (DOE), BNLmore » manages its world-class scientific research with particular sensitivity to environmental and community issues. BNL's motto, ''Exploring Life's Mysteries...Protecting its Future'', reflects BNL's management philosophy to fully integrate environmental stewardship into all facets of its missions, with a health balance between science and the environment.« less

A wire scanner system for characterizing the BNL energy recovery LINAC beam position monitor system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michnoff R.; Biscardi, C.; Cerniglia, P.

2012-04-15

A stepper motor controlled wire scanner system has recently been modified to support testing of the Brookhaven National Laboratory (BNL) Collider-Accelerator department's Energy Recovery Linac (ERL) beam position monitor (BPM) system. The ERL BPM consists of four 9.33 mm diameter buttons mounted at 90 degree spacing in a cube with 1.875 inch inside diameter. The buttons were designed by BNL and fabricated by Times Microwave Systems. Libera brilliance single pass BPM electronic modules with 700 MHz bandpass filter, manufactured by Instrumentation Technologies, will be used to measure the transverse beam positions at 14 locations around the ERL. The wire scannermore » assembly provides the ability to measure the BPM button response to a pulsed wire, and evaluate and calibrate the Libera position measurement electronics. A description of the wire scanner system and test result data will be presented.« less

Multipacting simulation and test results of BNL 704 MHz SRF gun

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu W.; Belomestnykh, S.; Ben-Zvi, I.

The BNL 704MHz SRF gun has a grooved choke joint to support the photo-cathode. Due to the distortion of grooves at the choke joint during the BCP for the choke joint, several multipacting barriers showed up when it was tested with Nb cathode stalk at JLab. We built a setup to use the spare large grain SRF cavity to test and condition the multipacting at BNL with various power sources up to 50kW. The test is carried out in three stages: testing the cavity performance without cathode, testing the cavity with the Nb cathode stalk that was used at Jlab,more » and testing the cavity with a copper cathode stalk that is based on the design for the SRF gun. This paper summarizes the results of multipacting simulation, and presents the large grain cavity test setup and the test results.« less

NGSPN @ BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pepper, S. E.; Bachner, K.; Gomera, J.

Brookhaven National Laboratory’s (BNL’s) Nonproliferation and National Security Department hosted the Next Generation Safeguards Professional Network (NGSPN) at BNL September 6-9, 2016. Thirteen representatives from seven Department of Energy National Laboratories, including two from BNL, participated in the four-day meeting. The NGSPN meeting was sponsored by the Office of International Nuclear Safeguards (NA-241) of the National Nuclear Security Administration, which provided funding for BNL’s development and conduct of the meeting program and the participant’s labor and travel. NGSPN meetings were previously held at Savannah River National Laboratory, Oak Ridge National Laboratory, Idaho National Laboratory, Sandia National Laboratories, and Los Alamosmore » National Laboratory. The purpose of NGSPN is to provide a forum for early-career international safeguards practitioners to network with their peers, to meet international safeguards experts from other institutions and to learn about organizations other than their employers who contribute to international safeguards.« less

The Muon $g$-$2$ Experiment at Fermilab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gohn, Wesley

A new measurement of the anomalous magnetic moment of the muon,more » $$a_{\\mu} \\equiv (g-2)/2$$, will be performed at the Fermi National Accelerator Laboratory with data taking beginning in 2017. The most recent measurement, performed at Brookhaven National Laboratory (BNL) and completed in 2001, shows a 3.5 standard deviation discrepancy with the standard model value of $$a_\\mu$$. The new measurement will accumulate 21 times the BNL statistics using upgraded magnet, detector, and storage ring systems, enabling a measurement of $$a_\\mu$$ to 140 ppb, a factor of 4 improvement in the uncertainty the previous measurement. This improvement in precision, combined with recent improvements in our understanding of the QCD contributions to the muon $g$-$2$, could provide a discrepancy from the standard model greater than 7$$\\sigma$$ if the central value is the same as that measured by the BNL experiment, which would be a clear indication of new physics.« less

Laboratory Directed Research and Development Program Activities for FY 2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newman,L.

2007-12-31

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annuallymore » in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in support of RHIC and the Light Source and any of the Strategic Initiatives listed at the LDRD web site. These included support for NSLS-II, RHIC evolving to a quantum chromo dynamics (QCD) lab, nanoscience, translational and biomedical neuroimaging, energy and, computational sciences. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence and a means to address national needs within the overall mission of the DOE and BNL.« less

Enhanced particle fluxes and heterotrophic bacterial activities in Gulf of Mexico bottom waters following storm-induced sediment resuspension

NASA Astrophysics Data System (ADS)

Ziervogel, K.; Dike, C.; Asper, V.; Montoya, J.; Battles, J.; D`souza, N.; Passow, U.; Diercks, A.; Esch, M.; Joye, S.; Dewald, C.; Arnosti, C.

2016-07-01

Bottom nepheloid layers (BNLs) in the deep sea transport and remobilize considerable amounts of particulate matter, enhancing microbial cycling of organic matter in cold, deep water environments. We measured bacterial abundance, bacterial protein production, and activities of hydrolytic enzymes within and above a BNL that formed in the deep Mississippi Canyon, northern Gulf of Mexico, shortly after Hurricane Isaac had passed over the study area in late August 2012. The BNL was detected via beam attenuation in CTD casts over an area of at least 3.5 km2, extending up to 200 m above the seafloor at a water depth of 1500 m. A large fraction of the suspended matter in the BNL consisted of resuspended sediments, as indicated by high levels of lithogenic material collected in near-bottom sediment traps shortly before the start of our sampling campaign. Observations of suspended particle abundance and sizes throughout the water column, using a combined camera-CTD system (marine snow camera, MSC), revealed the presence of macroaggregates (>1 mm in diameter) within the BNL, indicating resuspension of canyon sediments. A distinct bacterial response to enhanced particle concentrations within the BNL was evident from the observation that the highest enzymatic activities (peptidase, β-glucosidase) and protein production (3H-leucine incorporation) were found within the most particle rich sections of the BNL. To investigate the effects of enhanced particle concentrations on bacterial activities in deep BNLs more directly, we conducted laboratory experiments with roller bottles filled with bottom water and amended with experimentally resuspended sediments from the study area. Macroaggregates formed within 1 day from resuspended sediments; by day 4 of the incubation bacterial cell numbers in treatments with resuspended sediments were more than twice as high as in those lacking sediment suspensions. Cell-specific enzymatic activities were also generally higher in the sediment-amended compared to the unamended treatments. The broader range and higher activities of polysaccharide hydrolases in the presence of resuspended sediments compared to the unamended water reflected enzymatic capabilities typical for benthic bacteria. Our data suggest that the formation of BNLs in the deep Gulf of Mexico can lead to transport of sedimentary organic matter into bottom waters, stimulating bacterial food web interactions. Such storm-induced resuspension may represent a possible mechanism for the redistribution of sedimented oil-fallout from the Deepwater Horizon spill in 2010.

Designing acoustics for linguistically diverse classrooms: Effects of background noise, reverberation and talker foreign accent on speech comprehension by native and non-native English-speaking listeners

NASA Astrophysics Data System (ADS)

Peng, Zhao Ellen

The current classroom acoustics standard (ANSI S12.60-2010) recommends core learning spaces not to exceed background noise level (BNL) of 35 dBA and reverberation time (RT) of 0.6 second, based on speech intelligibility performance mainly by the native English-speaking population. Existing literature has not correlated these recommended values well with student learning outcomes. With a growing population of non-native English speakers in American classrooms, the special needs for perceiving degraded speech among non-native listeners, either due to realistic room acoustics or talker foreign accent, have not been addressed in the current standard. This research seeks to investigate the effects of BNL and RT on the comprehension of English speech from native English and native Mandarin Chinese talkers as perceived by native and non-native English listeners, and to provide acoustic design guidelines to supplement the existing standard. This dissertation presents two studies on the effects of RT and BNL on more realistic classroom learning experiences. How do native and non-native English-speaking listeners perform on speech comprehension tasks under adverse acoustic conditions, if the English speech is produced by talkers of native English (Study 1) versus native Mandarin Chinese (Study 2)? Speech comprehension materials were played back in a listening chamber to individual listeners: native and non-native English-speaking in Study 1; native English, native Mandarin Chinese, and other non-native English-speaking in Study 2. Each listener was screened for baseline English proficiency level, and completed dual tasks simultaneously involving speech comprehension and adaptive dot-tracing under 15 acoustic conditions, comprised of three BNL conditions (RC-30, 40, and 50) and five RT scenarios (0.4 to 1.2 seconds). The results show that BNL and RT negatively affect both objective performance and subjective perception of speech comprehension, more severely for non-native listeners than for native listeners. While the presence of foreign accent is generally detrimental, an interlanguage benefit was identified on both speech comprehension and the self-report frustration and perceived performance ratings, specifically for non-native listeners with matched foreign accent as the talker. Suggested design guidelines for BNL and RT are identified for attaining optimal speech comprehension performance to improve classroom acoustics for the non-native English-speaking population.

Wake-field and space charge effects on high brightness beams calculations and measured results for the laser driven photoelectrons at BNL-ATF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parsa, Z.

1993-05-01

We discuss the formalism used to study the effects of the interactions between the highly charged particles and the fields in the accelerating structure, including space charge and wake fields. Some of our calculations and numerical simulation results obtained for the Brookhaven National Laboratory (BNL) high-brightness photoelectron beam at the Accelerator Test Facility (ATF) and the measured data at ATF are also included.

BNL program in support of LWR degraded-core accident analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ginsberg, T.; Greene, G.A.

1982-01-01

Two major sources of loading on dry watr reactor containments are steam generatin from core debris water thermal interactions and molten core-concrete interactions. Experiments are in progress at BNL in support of analytical model development related to aspects of the above containment loading mechanisms. The work supports development and evaluation of the CORCON (Muir, 1981) and MARCH (Wooton, 1980) computer codes. Progress in the two programs is described in this paper. 8 figures.

Evidence for higher order QED effects in e+ e- pair production at the BNL Relativistic Heavy Ion Collider.

PubMed

Baltz, A J

2008-02-15

A new lowest order QED calculation for BNL Relativistic Heavy-Ion Collider e+ e- pair production has been carried out with a phenomenological treatment of the Coulomb dissociation of the heavy-ion nuclei observed in the STAR ZDC triggers. The lowest order QED result for the experimental acceptance is nearly 2 standard deviations larger than the STAR data. A corresponding higher-order QED calculation is consistent with the data.

Computationally Efficient Modeling of Hydrocarbon Oxidation Chemistry and Flames Using Constituents and Species

DTIC Science & Technology

2012-02-10

1 Nc X l Dil bNl = 1 Nc X l Dil ÃX k bClkNk! . (19) Finally, it is necessary to compute, from the Dil coefficients, a global diffusion coefficient...exists a mole fraction XCk such that Nk ’ NcXCk. Therefore, X l,k Dil bClk XCk = 1 Nc X l Dil bNl = 1 Nc X l Dil ÃX k bClkNk! . (20) Finally, it is

Power Spectrum Analysis of Physikalisch-Technische Bundesanstalt Decay-Rate Data: Evidence for Solar Rotational Modulation

NASA Astrophysics Data System (ADS)

Sturrock, P. A.; Buncher, J. B.; Fischbach, E.; Gruenwald, J. T.; Javorsek, D.; Jenkins, J. H.; Lee, R. H.; Mattes, J. J.; Newport, J. R.

2010-12-01

Evidence for an anomalous annual periodicity in certain nuclear-decay data has led to speculation on a possible solar influence on nuclear processes. We have recently analyzed data concerning the decay rates of 36Cl and 32Si, acquired at the Brookhaven National Laboratory (BNL), to search for evidence that might be indicative of a process involving solar rotation. Smoothing of the power spectrum by weighted-running-mean analysis leads to a significant peak at frequency 11.18 year-1, which is lower than the equatorial synodic rotation rates of the convection and radiative zones. This article concerns measurements of the decay rates of 226Ra acquired at the Physikalisch-Technische Bundesanstalt (PTB) in Germany. We find that a similar (but not identical) analysis yields a significant peak in the PTB dataset at frequency 11.21 year-1, and a peak in the BNL dataset at 11.25 year-1. The change in the BNL result is not significant, since the uncertainties in the BNL and PTB analyses are estimated to be 0.13 year-1 and 0.07 year-1, respectively. Combining the two running means by forming the joint power statistic leads to a highly significant peak at frequency 11.23 year-1. We will briefly comment on the possible implications of these results for solar physics and for particle physics.

CRYSNET manual. Informal report. [Hardware and software of crystallographic computing network

DOE Office of Scientific and Technical Information (OSTI.GOV)

None,

1976-07-01

This manual describes the hardware and software which together make up the crystallographic computing network (CRYSNET). The manual is intended as a users' guide and also provides general information for persons without any experience with the system. CRYSNET is a network of intelligent remote graphics terminals that are used to communicate with the CDC Cyber 70/76 computing system at the Brookhaven National Laboratory (BNL) Central Scientific Computing Facility. Terminals are in active use by four research groups in the field of crystallography. A protein data bank has been established at BNL to store in machine-readable form atomic coordinates and othermore » crystallographic data for macromolecules. The bank currently includes data for more than 20 proteins. This structural information can be accessed at BNL directly by the CRYSNET graphics terminals. More than two years of experience has been accumulated with CRYSNET. During this period, it has been demonstrated that the terminals, which provide access to a large, fast third-generation computer, plus stand-alone interactive graphics capability, are useful for computations in crystallography, and in a variety of other applications as well. The terminal hardware, the actual operations of the terminals, and the operations of the BNL Central Facility are described in some detail, and documentation of the terminal and central-site software is given. (RWR)« less

A Comprehensive Investigation and Coupler Design for Higher-Order Modes in the BNL Energy Recovery Linear Accelerator

NASA Astrophysics Data System (ADS)

Marques, Carlos

A next generation Energy Recovery Linac (ERL) is under development in the Collider-Accelerator Department at Brookhaven National Laboratory (BNL). This ERL uses a superconducting radio frequency (SFR) cavity to produce an electric field gradient ideal to accelerate charged particles. As with many accelerators, higher-order modes (HOMs) can be induced by a beam of charged particles traversing the linear accelerator cavity. The excitation of these modes can result in problematic single and multi-bunch effects and also produce undesirable heat loads to the cryogenic system. Understanding HOM prevalence and structure inside the accelerator cavity is crucial for devising a procedure for extracting HOM power and promoting excellent beam quality. In this work, a method was created to identify and characterize HOMs using a perturbation technique on a copper (Cu) cavity prototype of the BNL3 linac and a double lambda/4 crab cavity. Both analyses and correlation between simulated and measured results are shown. A coaxial to dual-ridge waveguide HOM coupler was designed, constructed and implemented to extract power from HOMs simultaneously making an evanescent fundamental mode for the BNL3 cavity. A full description of the design is given along with a simulated analysis of its performance. Comparison between previous HOM coupler designs as well as correspondence between simulation and measurement is also given.

Type A verification report for the high flux beam reactor stack and grounds, Brookhaven National Laboratory, Upton, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harpenau, Evan M.

The U.S. Department of Energy (DOE) Order 458.1 requires independent verification (IV) of DOE cleanup projects (DOE 2011). The Oak Ridge Institute for Science and Education (ORISE) has been designated as the responsible organization for IV of the High Flux Beam Reactor (HFBR) Stack and Grounds area at Brookhaven National Laboratory (BNL) in Upton, New York. The IV evaluation may consist of an in-process inspection with document and data reviews (Type A Verification) or a confirmatory survey of the site (Type B Verification). DOE and ORISE determined that a Type A verification of the documents and data for the HFBRmore » Stack and Grounds: Survey Units (SU) 6, 7, and 8 was appropriate based on the initial survey unit classification, the walkover surveys, and the final analytical results provided by the Brookhaven Science Associates (BSA). The HFBR Stack and Grounds surveys began in June 2011 and were completed in September 2011. Survey activities by BSA included gamma walkover scans and sampling of the as-left soils in accordance with the BSA Work Procedure (BNL 2010a). The Field Sampling Plan - Stack and Remaining HFBR Outside Areas (FSP) stated that gamma walk-over surveys would be conducted with a bare sodium iodide (NaI) detector, and a collimated detector would be used to check areas with elevated count rates to locate the source of the high readings (BNL 2010b). BSA used the Mult- Agency Radiation Survey and Site Investigation Manual (MARSSIM) principles for determining the classifications of each survey unit. Therefore, SUs 6 and 7 were identified as Class 1 and SU 8 was deemed Class 2 (BNL 2010b). Gamma walkover surveys of SUs 6, 7, and 8 were completed using a 2X2 NaI detector coupled to a data-logger with a global positioning system (GPS). The 100% scan surveys conducted prior to the final status survey (FSS) sampling identified two general soil areas and two isolated soil locations with elevated radioactivity. The general areas of elevated activity identified were investigated further with a collimated NaI detector. The uncollimated average gamma count rate was less than 15,000 counts per minute (cpm) for the SU 6, 7, and 8 composite area (BNL 2011a). Elevated count rates were observed in portions of each survey unit. The general areas of elevated counts near the Building 801 ventilation and operations and the entry to the Stack were determined to be directly related to the radioactive processes in those structures. To compensate for this radioactive shine, a collimated or shielded detector was used to lower the background count rate (BNL 2011b and c). This allowed the surveyor(s) to distinguish between background and actual radioactive contamination. Collimated gamma survey count rates in these shine affected areas were below 9,000 cpm (BNL 2011a). The average background count rate of 7,500 cpm was reported by BSA for uncollimated NaI detectors (BNL 2011d). The average collimated background ranged from 4,500-6,500 cpm in the westernmost part of SU 8 and from 2,000-3,500 cpm in all other areas (BNL 2011e). Based on these data, no further investigations were necessary for these general areas. SU 8 was the only survey unit that exhibited verified elevated radioactivity levels. The first of two isolated locations of elevated radioactivity had an uncollimated direct measurement of 50,000 cpm with an area background of 7,500 cpm (BNL 2011f). The second small area exhibiting elevated radiation levels was identified at a depth of 6 inches from the surface. The maximum reported count rate of 28,000 cpm was observed during scanning (BNL 2011g). The affected areas were remediated, and the contaminated soils were placed in an intermodal container for disposal. BSA's post-remediation walkover surveys were expanded to include a 10-foot radius around the excavated locations, and it was determined that further investigation was not required for these areas (BNL 2011 f and g). The post-remediation soil samples were collected and analyzed with onsite gamma spectroscopy equipment. These samples were also included with the FSS samples that were analyzed at an offsite facility for the primary radionuclides of concern (ROCs) (i.e., cesium-137, strontium-90, and radium-226). Analysis included full spectrum gamma spectroscopy for all samples. Sr-90 analysis was completed on all samples from SUs 6 and 7. However Sr-90 was only completed on the cores, composites, field blank and duplicate samples in SU 8. Alpha spectroscopy as well as liquid scintillation performed for tritium, carbon-14, and nickel-63 concentrations were completed on the composite samples from SUs 6 and 7. Various cores, composites, and samples from the remediated areas of SU 8 received alpha spectroscopy as well as liquid scintillation analyses for tritium, carbon-14, and nickel-63 to determine respective ROC concentrations (BNL 2011 h, i, and j). BSA submitted the FSS data and analytical results to demonstrate that remediation efforts complied with the specified cleanup goal of less than or equal to 15 millirem per year (mrem/yr) above background to a resident in 50 years (BNL 2011a through j). ORISE has reviewed the project documentation and FSS data for the HFBR Stack and Grounds: SUs 6, 7, and 8. The highest concentrations of the primary ROCs reported were 5.92 picocuries per gram (pCi/g) for Cs-137 and 2.03 pCi/g for Sr-90, with both ROCs having the qualifier for the sample result as less than the minimum detectable activity (MDA). For Ra-226, the highest detected concentration from the FSS data provided was 0.682 pCi/g. Other potential secondary contaminants were below their respective MDAs. Therefore, ORISE is of the opinion that BSA has provided sufficient evidence to demonstrate compliance with the 15 mrem/yr cleanup objectives for the final status survey data provided.« less

Development and In Situ Characterization of New Electrolyte and Electrode materials for Rechargeable Lithium Batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, X -Q; Xing, X K; Daroux, M

The object of this project is to develop new electrolyte and cathode materials for rechargeable lithium batteries, especially for lithium ion and lithium polymer batteries. Enhancing performance, reducing cost, and replacing toxic materials by environmentally benign materials, are strategic goals of DOE in lithium battery research. This proposed project will address these goals on two important material studies, namely the new electrolytes and new cathode materials. For the new electrolyte materials, aza based anion receptors as additives, organic lithium salts and plasticizers which have been developed by BNL team under Energy Research programs of DOE, will be evaluated by Gouldmore » for potential use in commercial battery cells. All of these three types of compounds are aimed to enhance the conductivity and lithium transference number of lithium battery electrolytes and reduce the use of toxic salts in these electrolytes. BNL group will be working closely with Gould to further develop these compounds for commercialization. For the cathode material studies, BNL efforts wi U be focused on developing new superior characterization methclds, especially in situ techniques utilize the unique user facility of DOE at BNL, namely the National Synchrotrons Light Source (NSLS). In situ x-ray absorption and x-ray diftlaction spectroscopy will be used to study the relationship between performance and the electronic and structural characteristics of intercalation compounds such as LiNi0 2, LiCo0 2, and LiMn 20 4 spinel. The study will be focused on LiMn 20 4 spinel materials. Gould team will contribute their expertise in choosing the most promising compounds, providing overall performance requirements, and will use the results of this study to guide their procedure for quality control. The knowledge gained through this project will not only benefit Gould and BNL, but will be very valuable to the scientific community in battery research.« less

Review of APR+ Level 2 PSA. Revision 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lehner, John R.; Mubayi, Vinod; Pratt, W. Trevor

2012-02-17

Brookhaven National Laboratory (BNL) assisted the Korea Institute of Nuclear Safety (KINS) in reviewing the Level 2 Probabilistic Safety Assessment (PSA) of the APR+ Advanced Pressurized Water Reactor (PWR) prepared by the Korea Hydro & Nuclear Power Co., Ltd (KHNP) and KEPCO Engineering & Construction Co., Inc. (KEPCO-E&C). The work described in this report involves a review of the APR+ Level 2 PSA submittal [Ref. 1]. The PSA and, therefore, the review is limited to consideration of accidents initiated by internal events. As part of the review process, the review team also developed three sets of Requests for Additional Informationmore » (RAIs). These RAIs were provided to KHNP and KEPCO-E&C for their evaluation and response. This final detailed report documents the review findings for each technical element of the PSA and includes consideration of all of the RAIs made by the reviewers as well as the associated responses. This final report was preceded by an interim report [Ref. 2] that focused on identifying important issues regarding the PSA. In addition, a final meeting on the project was held at BNL on November 21-22, 2011, where BNL and KINS reviewers discussed their preliminary review findings with KHNP and KEPCO-E&C staffs. Additional information obtained during this final meeting was also used to inform the review findings of this final report. The review focused not only on the robustness of the APR+ design to withstand severe accidents, but also on the capability and acceptability of the Level 2 PSA in terms of level of detail and completeness. The Korean nuclear regulatory authorities will decide whether the PSA is acceptable and the BNL review team is providing its comments for KINS consideration. Section 2.0 provides the basis for the BNL review. Section 3.0 presents the review of each technical element of the PSA. Conclusions and a summary are presented in Section 4.0. Section 5.0 contains the references.« less

Interferon-gamma alone triggers the production of nitric oxide from serum-starved BNL CL.2, murine embryonic liver cells.

PubMed

Pae, H O; Yoo, J C; Choi, B M; Paik, S G; Kim, Y H; Jin, H S; Chung, H T

1999-01-01

A previous study has demonstrated that both interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS) were needed to induce the production of nitric oxide (NO) in BNL CL.2 cells, murine embryonic liver cells. We here demonstrate that when BNL CL.2 cells were cultured with serum-free medium, they were induced to produce NO by the stimulation of IFN-gamma alone. BNL CL.2 cells were cultured with serum-free or serum-containing medium for 1-3 days and then stimulated to synthesize NO by IFN-gamma. Surprisingly, only serum-starved cells showed significant amount of nitrite accumulation and iNOS protein expression in response to IFN-gamma in dose- and time-dependent manners, but serum-supplied cells did not. When the cells were stimulated with IFN-gamma, tumor necrosis factor-alpha (TNF-alpha), or LPS in combinations, only the combination of IFN-gamma and LPS produced more NO than that produced by IFN-gamma alone. The production of NO by the cells stimulated with IFN-gamma or IFN-gamma plus LPS was blocked by the addition of N(G)-monomethyl-L-arginine (N(G)MMA), a NO synthesis inhibitor. To address the intracellular signal pathway responsible for the production of NO by the cells stimulated with IFN-gamma aloneor IFN-gamma plus LPS, we examined the effects of several protein kinase inhibitors on the production of NO from the cells. The production of NO was significantly inhibited by protein tyrosine kinase (PTK) inhibitors, genistein and herbimycin A, but not by protein kinase A or C inhibitors. These results suggest that the deprivation of serum from BNL CL.2 cell culture medium might prime the cells to induce NO synthesis when the cells are triggered by IFN-gamma and the involvement of PTK signal transduction pathway in the expression of inducible NO synthase gene in murine hepatoma cells.

Anti-hepatitis B virus activity of Boehmeria nivea leaf extracts in human HepG2.2.15 cells

PubMed Central

WEI, JINGCHEN; LIN, LIANKU; SU, XIAOJIAN; QIN, SHAOYAN; XU, QING; TANG, ZUNIAN; DENG, YAN; ZHOU, YUEHAN; HE, SONGQING

2014-01-01

Boehmeria nivea (Linn.) Gaudich of the Urticaceae family is a perennial ratoon herbal plant, the root of which is used in traditional Chinese medicine and possesses a variety of pharmacological properties. The 20% ethanol Boehmeria nivea root extract was shown to exert an anti-hepatitis B virus (HBV) effect in vitro and in vivo; however, whether the Boehmeria nivea leaf (BNL) extract possesses similar properties has not been determined. In this study, we aimed to investigate the anti-HBV effects of the BNL extract in HepG2.2.15 cells transfected with human HBV DNA. Our results demonstrated that the secretion of HBsAg and HBeAg was reduced in HepG2.2.15 cells treated with the BNL extract, without any recorded cytotoxic effects. In addition, the chloroform fraction (CF) and ethyl acetate fraction (EAF) of BNL were shown to be more potent compared to the other fractions: CF (100 mg/l) inhibited the secretion of HBsAg by 94.00±1.78% [inhibitory concentration 50 (IC50) = 20.92 mg/l] and that of HBeAg by 100.19±0.35% (IC50=19.67 mg/l) after 9 days of treatment. Similarly, EAF (200 mg/l) inhibited the secretion of HBsAg by 89.95±2.26% (IC50=39.90 mg/l) and that of HBeAg by 98.90±1.42% (IC50=36.45 mg/l). Furthermore, we observed that the content of HBV DNA in the medium secreted by the HepG2.2.15 cells was significantly decreased under CF (100 mg/l) or EAF (200 mg/l) treatment. Thus, we concluded that the BNL extracts exhibited anti-HBV activity, with CF and EAF being the most potent among the fractions. PMID:24649087

Anti-hepatitis B virus activity of Boehmeria nivea leaf extracts in human HepG2.2.15 cells.

PubMed

Wei, Jingchen; Lin, Lianku; Su, Xiaojian; Qin, Shaoyan; Xu, Qing; Tang, Zunian; Deng, Yan; Zhou, Yuehan; He, Songqing

2014-01-01

Boehmeria nivea (Linn.) Gaudich of the Urticaceae family is a perennial ratoon herbal plant, the root of which is used in traditional Chinese medicine and possesses a variety of pharmacological properties. The 20% ethanol Boehmeria nivea root extract was shown to exert an anti-hepatitis B virus (HBV) effect in vitro and in vivo ; however, whether the Boehmeria nivea leaf (BNL) extract possesses similar properties has not been determined. In this study, we aimed to investigate the anti-HBV effects of the BNL extract in HepG2.2.15 cells transfected with human HBV DNA. Our results demonstrated that the secretion of HBsAg and HBeAg was reduced in HepG2.2.15 cells treated with the BNL extract, without any recorded cytotoxic effects. In addition, the chloroform fraction (CF) and ethyl acetate fraction (EAF) of BNL were shown to be more potent compared to the other fractions: CF (100 mg/l) inhibited the secretion of HBsAg by 94.00±1.78% [inhibitory concentration 50 (IC 50 ) = 20.92 mg/l] and that of HBeAg by 100.19±0.35% (IC 50 =19.67 mg/l) after 9 days of treatment. Similarly, EAF (200 mg/l) inhibited the secretion of HBsAg by 89.95±2.26% (IC 50 =39.90 mg/l) and that of HBeAg by 98.90±1.42% (IC 50 =36.45 mg/l). Furthermore, we observed that the content of HBV DNA in the medium secreted by the HepG2.2.15 cells was significantly decreased under CF (100 mg/l) or EAF (200 mg/l) treatment. Thus, we concluded that the BNL extracts exhibited anti-HBV activity, with CF and EAF being the most potent among the fractions.

Radar Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory (BNL) Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jensen, Michael P; Giangrande, Scott E; Bartholomew, Mary Jane

The Radar Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory (BNL) [http://www.arm.gov/campaigns/osc2013rwpcf] campaign was scheduled to take place from 15 July 2013 through 15 July 2015 (or until shipped for the next U.S. Department of Energy Atmospheric Radiation Measurement [ARM] Climate Research Facility first Mobile Facility [AMF1] deployment). The campaign involved the deployment of the AMF1 Scintec 915 MHz Radar Wind Profiler (RWP) at BNL, in conjunction with several other ARM, BNL and National Weather Service (NWS) instruments. The two main scientific foci of the campaign were: 1) To provide profiles of the horizontal wind to be used tomore » test and validate short-term cloud advection forecasts for solar-energy applications and 2) to provide vertical profiling capabilities for the study of dynamics (i.e., vertical velocity) and hydrometeors in winter storms. This campaign was a serendipitous opportunity that arose following the deployment of the RWP at the Two-Column Aerosol Project (TCAP) campaign in Cape Cod, Massachusetts and restriction from participation in the Green Ocean Amazon 2014/15 (GoAmazon 2014/15) campaign due to radio-frequency allocation restriction for international deployments. The RWP arrived at BNL in the fall of 2013, but deployment was delayed until fall of 2014 as work/safety planning and site preparation were completed. The RWP further encountered multiple electrical failures, which eventually required several shipments of instrument power supplies and the final amplifier to the vendor to complete repairs. Data collection began in late January 2015. The operational modes of the RWP were changed such that in addition to collecting traditional profiles of the horizontal wind, a vertically pointing mode was also included for the purpose of precipitation sensing and estimation of vertical velocities. The RWP operated well until the end of the campaign in July 2015 and collected observations for more than 20 precipitation events.« less

BNL severe-accident sequence experiments and analysis program. [PWR; BWR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greene, G.A.; Ginsberg, T.; Tutu, N.K.

1983-01-01

In the analysis of degraded core accidents, the two major sources of pressure loading on light water reactor containments are: steam generation from core debris-water thermal interactions; and molten core-concrete interactions. Experiments are in progress at BNL in support of analytical model development related to aspects of the above containment loading mechanisms. The work supports development and evaluation of the CORCON (Muir, 1981) and MARCH (Wooton, 1980) computer codes. Progress in the two programs is described.

BEAM DYNAMICS SIMULATIONS FOR A DC GUN BASED INJECTOR FOR PERL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

ZHOU,F.; BEN-ZVI,I.; WANG,X.J.

2001-06-18

The National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory (BNL) is considering an upgrade based on the Photoinjected Energy Recovering Linac (PERL). The various injector schemes for this machine are being extensively investigated at BNL. One of the possible options is photocathode DC gun. The schematic layout of a PERL DC gun based injector and its preliminary beam dynamics are presented in this paper. The transverse and longitudinal emittance of photo-electron beam were optimized for a DC field 500 kV.

Radionuclide development at BNL for nuclear medicine therapy.

PubMed

Mausner, L F; Kolsky, K L; Joshi, V; Srivastava, S C

1998-04-01

Radionuclides with medium energy beta emission and a several day half-life have often been viewed as attractive candidates for radioimmunotherapy. Among the most promising in this category are 47Sc, 67Cu, 153Sm, 188Re, and 199Au. The production of 67Cu, 153Sm, 199Au at BNL is summarized and the development of the latest candidate for this application, 47Sc, is described in detail. We also summarize the development of another important therapeutic radionuclide, 117mSn for bone pain palliation.

Fragility Analysis Methodology for Degraded Structures and Passive Components in Nuclear Power Plants - Illustrated using a Condensate Storage Tank

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nie, J.; Braverman, J.; Hofmayer, C.

2010-06-30

The Korea Atomic Energy Research Institute (KAERI) is conducting a five-year research project to develop a realistic seismic risk evaluation system which includes the consideration of aging of structures and components in nuclear power plants (NPPs). The KAERI research project includes three specific areas that are essential to seismic probabilistic risk assessment (PRA): (1) probabilistic seismic hazard analysis, (2) seismic fragility analysis including the effects of aging, and (3) a plant seismic risk analysis. Since 2007, Brookhaven National Laboratory (BNL) has entered into a collaboration agreement with KAERI to support its development of seismic capability evaluation technology for degraded structuresmore » and components. The collaborative research effort is intended to continue over a five year period. The goal of this collaboration endeavor is to assist KAERI to develop seismic fragility analysis methods that consider the potential effects of age-related degradation of structures, systems, and components (SSCs). The research results of this multi-year collaboration will be utilized as input to seismic PRAs. In the Year 1 scope of work, BNL collected and reviewed degradation occurrences in US NPPs and identified important aging characteristics needed for the seismic capability evaluations. This information is presented in the Annual Report for the Year 1 Task, identified as BNL Report-81741-2008 and also designated as KAERI/RR-2931/2008. The report presents results of the statistical and trending analysis of this data and compares the results to prior aging studies. In addition, the report provides a description of U.S. current regulatory requirements, regulatory guidance documents, generic communications, industry standards and guidance, and past research related to aging degradation of SSCs. In the Year 2 scope of work, BNL carried out a research effort to identify and assess degradation models for the long-term behavior of dominant materials that are determined to be risk significant to NPPs. Multiple models have been identified for concrete, carbon and low-alloy steel, and stainless steel. These models are documented in the Annual Report for the Year 2 Task, identified as BNL Report-82249-2009 and also designated as KAERI/TR-3757/2009. This report describes the research effort performed by BNL for the Year 3 scope of work. The objective is for BNL to develop the seismic fragility capacity for a condensate storage tank with various degradation scenarios. The conservative deterministic failure margin method has been utilized for the undegraded case and has been modified to accommodate the degraded cases. A total of five seismic fragility analysis cases have been described: (1) undegraded case, (2) degraded stainless tank shell, (3) degraded anchor bolts, (4) anchorage concrete cracking, and (5)a perfect combination of the three degradation scenarios. Insights from these fragility analyses are also presented.« less

Proceedings of RIKEN BNL Research Center Workshop: The Physics of p ↑+A Collisions at RHIC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bai, Mei; Goto, Yuji; Heppelmann, Steve

The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the "Rikagaku Kenkyusho" (RIKEN, The Institute of Physical and Chemical Research) of Japan. The Memorandum of Understanding between RIKEN and BNL, initiated in 1997, has been renewed in 2002, 2007 and again in 2012. The Center is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has both a theory and experimental component. The RBRC Theory Group and the RBRC Experimental Group consistsmore » of a total of 25-30 researchers. Positions include the following: full time RBRC Fellow, half-time RHIC Physics Fellow, and full-time postdoctoral Research Associate. The RHIC Physics Fellows hold joint appointments with RBRC and other institutions and have tenure track positions at their respective universities or BNL. To date, RBRC has over 95 graduates (Fellows and Post- docs) of which approximately 40 theorists and 20 experimenters have already attained tenure positions at major institutions worldwide. Beginning in 2001 a new RIKEN Spin Program (RSP) category was implemented at RBRC. These appointments are joint positions of RBRC and RIKEN and include the following positions in theory and experiment: RSP Researchers, RSP Research Associates, and Young Researchers, who are mentored by senior RBRC Scientists. A number of RIKEN Jr. Research Associates and Visiting Scientists also contribute to the physics program at the Center. RBRC has an active workshop program on strong interaction physics with each workshop focused on a specific physics problem. In most cases all the talks are made available on the RBRC website. In addition, highlights to each speaker’s presentation are collected to form proceedings which can therefore be made available within a short time after the workshop. To date there are over one hundred proceeding volumes available. A 10 teraflops RBRC QCDOC computer funded by RIKEN, Japan, was unveiled at a dedication ceremony at BNL on May 26, 2005. This supercomputer was designed and built by individuals from Columbia University, IBM, BNL, RBRC, and the University of Edinburgh, with the U.S. D.O.E. Office of Science providing infrastructure support at BNL. Physics results were reported at the RBRC QCDOC Symposium following the dedication. QCDSP, a 0.6 teraflops parallel processor, dedicated to lattice QCD, was begun at the Center on February 19, 1998, was completed on August 28, 1998, and was decommissioned in 2006. It was awarded the Gordon Bell Prize for price performance in 1998. QCDOC was decommissioned in May 2012. The next generation computer in this sequence, QCDCQ (600 Teraflops), is currently operational and is expected to produce many more interesting discoveries in the future.« less

The role of dedicated data computing centers in the age of cloud computing

NASA Astrophysics Data System (ADS)

Caramarcu, Costin; Hollowell, Christopher; Strecker-Kellogg, William; Wong, Antonio; Zaytsev, Alexandr

2017-10-01

Brookhaven National Laboratory (BNL) anticipates significant growth in scientific programs with large computing and data storage needs in the near future and has recently reorganized support for scientific computing to meet these needs. A key component is the enhanced role of the RHIC-ATLAS Computing Facility (RACF) in support of high-throughput and high-performance computing (HTC and HPC) at BNL. This presentation discusses the evolving role of the RACF at BNL, in light of its growing portfolio of responsibilities and its increasing integration with cloud (academic and for-profit) computing activities. We also discuss BNL’s plan to build a new computing center to support the new responsibilities of the RACF and present a summary of the cost benefit analysis done, including the types of computing activities that benefit most from a local data center vs. cloud computing. This analysis is partly based on an updated cost comparison of Amazon EC2 computing services and the RACF, which was originally conducted in 2012.

Next Generation Muon g-2 Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hertzog, David W.

2015-12-02

I report on the progress of two new muon anomalous magnetic moment experiments, which are in advanced design and construction phases. The goal of Fermilab E989 is to reduce the experimental uncertainty ofmore » $$a_\\mu$$ from Brookhaven E821 by a factor of 4; that is, $$\\delta a_\\mu \\sim 16 \\times 10^{-11}$$, a relative uncertainty of 140~ppb. The method follows the same magic-momentum storage ring concept used at BNL, and pioneered previously at CERN, but muon beam preparation, storage ring internal hardware, field measuring equipment, and detector and electronics systems are all new or upgraded significantly. In contrast, J-PARC E34 will employ a novel approach based on injection of an ultra-cold, low-energy, muon beam injected into a small, but highly uniform magnet. Only a small magnetic focusing field is needed to maintain storage, which distinguishes it from CERN, BNL and Fermilab. E34 aims to roughly match the previous BNL precision in their Phase~1 installation.« less

The Drosophila homologue of SRF acts as a boosting mechanism to sustain FGF-induced terminal branching in the tracheal system.

PubMed

Gervais, Louis; Casanova, Jordi

2011-04-01

Recent data have demonstrated a crucial role for the transcription factor SRF (serum response factor) downstream of VEGF and FGF signalling during branching morphogenesis. This is the case for sprouting angiogenesis in vertebrates, axonal branching in mammals and terminal branching of the Drosophila tracheal system. However, the specific functions of SRF in these processes remain unclear. Here, we establish the relative contributions of the Drosophila homologues of FGF [Branchless (BNL)] and SRF [Blistered (BS)] in terminal tracheal branching. Conversely to an extended view, we show that BNL triggers terminal branching initiation in a DSRF-independent mechanism and that DSRF transcription induced by BNL signalling is required to maintain terminal branch elongation. Moreover, we report that increased and continuous FGF signalling can trigger tracheal cells to develop full-length terminal branches in the absence of DSRF transcription. Our results indicate that DSRF acts as an amplifying step to sustain the progression of terminal branch elongation even in the wild-type conditions of FGF signalling.

NGSI student activities in open source information analysis in support of the training program of the U.S. DOE laboratories for the entry into force of the additional protocol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandoval, M Analisa; Uribe, Eva C; Sandoval, Marisa N

2009-01-01

In 2008 a joint team from Los Alamos National Laboratory (LANL) and Brookhaven National Laboratory (BNL) consisting of specialists in training of IAEA inspectors in the use of complementary access activities formulated a training program to prepare the U.S. Doe laboratories for the entry into force of the Additional Protocol. As a major part of the support of the activity, LANL summer interns provided open source information analysis to the LANL-BNL mock inspection team. They were a part of the Next Generation Safeguards Initiative's (NGSI) summer intern program aimed at producing the next generation of safeguards specialists. This paper describesmore » how they used open source information to 'backstop' the LANL-BNL team's effort to construct meaningful Additional Protocol Complementary Access training scenarios for each of the three DOE laboratories, Lawrence Livermore National Laboratory, Idaho National Laboratory, and Oak Ridge National Laboratory.« less

Wide-cross whole-genome radiation hybrid mapping of cotton (Gossypium hirsutum L.).

PubMed Central

Gao, Wenxiang; Chen, Z Jeffrey; Yu, John Z; Raska, Dwaine; Kohel, Russell J; Womack, James E; Stelly, David M

2004-01-01

We report the development and characterization of a "wide-cross whole-genome radiation hybrid" (WWRH) panel from cotton (Gossypium hirsutum L.). Chromosomes were segmented by gamma-irradiation of G. hirsutum (n = 26) pollen, and segmented chromosomes were rescued after in vivo fertilization of G. barbadense egg cells (n = 26). A 5-krad gamma-ray WWRH mapping panel (N = 93) was constructed and genotyped at 102 SSR loci. SSR marker retention frequencies were higher than those for animal systems and marker retention patterns were informative. Using the program RHMAP, 52 of 102 SSR markers were mapped into 16 syntenic groups. Linkage group 9 (LG 9) SSR markers BNL0625 and BNL2805 had been colocalized by linkage analysis, but their order was resolved by differential retention among WWRH plants. Two linkage groups, LG 13 and LG 9, were combined into one syntenic group, and the chromosome 1 linkage group marker BNL4053 was reassigned to chromosome 9. Analyses of cytogenetic stocks supported synteny of LG 9 and LG 13 and localized them to the short arm of chromosome 17. They also supported reassignment of marker BNL4053 to the long arm of chromosome 9. A WWRH map of the syntenic group composed of linkage groups 9 and 13 was constructed by maximum-likelihood analysis under the general retention model. The results demonstrate not only the feasibility of WWRH panel construction and mapping, but also complementarity to traditional linkage mapping and cytogenetic methods. PMID:15280245

Enhanced seed oil production in canola by conditional expression of Brassica napus LEAFY COTYLEDON1 and LEC1-LIKE in developing seeds.

PubMed

Tan, Helin; Yang, Xiaohui; Zhang, Fengxia; Zheng, Xiu; Qu, Cunmin; Mu, Jinye; Fu, Fuyou; Li, Jiana; Guan, Rongzhan; Zhang, Hongsheng; Wang, Guodong; Zuo, Jianru

2011-07-01

The seed oil content in oilseed crops is a major selection trait to breeders. In Arabidopsis (Arabidopsis thaliana), LEAFY COTYLEDON1 (LEC1) and LEC1-LIKE (L1L) are key regulators of fatty acid biosynthesis. Overexpression of AtLEC1 and its orthologs in canola (Brassica napus), BnLEC1 and BnL1L, causes an increased fatty acid level in transgenic Arabidopsis plants, which, however, also show severe developmental abnormalities. Here, we use truncated napin A promoters, which retain the seed-specific expression pattern but with a reduced expression level, to drive the expression of BnLEC1 and BnL1L in transgenic canola. Conditional expression of BnLEC1 and BnL1L increases the seed oil content by 2% to 20% and has no detrimental effects on major agronomic traits. In the transgenic canola, expression of a subset of genes involved in fatty acid biosynthesis and glycolysis is up-regulated in developing seeds. Moreover, the BnLEC1 transgene enhances the expression of several genes involved in Suc synthesis and transport in developing seeds and the silique wall. Consistently, the accumulation of Suc and Fru is increased in developing seeds of the transgenic rapeseed, suggesting the increased carbon flux to fatty acid biosynthesis. These results demonstrate that BnLEC1 and BnL1L are reliable targets for genetic improvement of rapeseed in seed oil production.

Target and orbit feedback simulations of a muSR beamline at BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacKay, W. W.; Fischer, W.; Blaskiewicz, M.

Well-polarized positive surface muons are a tool to measure the magnetic properties of materials since the precession rate of the spin can be determined from the observation of the positron directions when the muons decay. The use of the AGS complex at BNL has been explored for a muSR facility previously. Here we report simulations of a beamline with a target inside a solenoidal field, and of an orbit feed-back system with single muon beam positioning monitors based on technology available today

The Muon g-2 experiment at Fermilab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chapelain, Antoine

The upcoming Fermilab E989 experiment will measure the muon anomalous magnetic moment aμ. This measurement is motivated by the previous measurement performed in 2001 by the BNL E821 experiment that reported a 3-4 standard deviation discrepancy between the measured value and the Standard Model prediction. The new measurement at Fermilab aims to improve the precision by a factor of four reducing the total uncertainty from 540 parts per billion (BNL E821) to 140 parts per billion (Fermilab E989). This paper gives the status of the experiment.

NGEE Arctic Zero Power Warming PhenoCamera Images, Barrow, Alaska, 2016

DOE Data Explorer

Shawn Serbin; Andrew McMahon; Keith Lewin; Kim Ely; Alistair Rogers

2016-11-14

StarDot NetCam SC pheno camera images collected from the top of the Barrow, BEO Sled Shed. The camera was installed to monitor the BNL TEST group's prototype ZPW (Zero Power Warming) chambers during the growing season of 2016 (including early spring and late fall). Images were uploaded to the BNL FTP server every 10 minutes and renamed with the date and time of the image. See associated data "Zero Power Warming (ZPW) Chamber Prototype Measurements, Barrow, Alaska, 2016" http://dx.doi.org/10.5440/1343066.

The Muon g-2 experiment at Fermilab

NASA Astrophysics Data System (ADS)

Chapelain, Antoine

2017-03-01

The upcoming Fermilab E989 experiment will measure the muon anomalous magnetic moment aμ. This measurement is motivated by the previous measurement performed in 2001 by the BNL E821 experiment that reported a 3-4 standard deviation discrepancy between the measured value and the Standard Model prediction. The new measurement at Fermilab aims to improve the precision by a factor of four reducing the total uncertainty from 540 parts per billion (BNL E821) to 140 parts per billion (Fermilab E989). This paper gives the status of the experiment.

Has the QCD critical point been signaled by observations at the BNL relativistic heavy ion collider?

PubMed

Lacey, Roy A; Ajitanand, N N; Alexander, J M; Chung, P; Holzmann, W G; Issah, M; Taranenko, A; Danielewicz, P; Stöcker, Horst

2007-03-02

The shear viscosity to entropy ratio (eta/s) is estimated for the hot and dense QCD matter created in Au+Au collisions at BNL Relativistic Heavy Ion Collider (square root[s_{NN}]=200 GeV). A very low value is found; eta/s approximately 0.1, which is close to the conjectured lower bound (1/4pi). It is argued that such a low value is indicative of thermodynamic trajectories for the decaying matter which lie close to the QCD critical end point.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney,J.P.; Fox, K.

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that maintains a primary mission focus the physical sciences, energy sciences, and life sciences, with additional expertise in environmental sciences, energy technologies, and national security. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2008 budget was $531.6 million. There are about 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to themore » U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Developlnent at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. Accordingly, this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2008. BNL expended $12 million during Fiscal Year 2008 in support of 69 projects. The program has two categories, the annual Open Call LDRDs and Strategic LDRDs, which combine to meet the overall objectives of the LDRD Program. Proposals are solicited annually for review and approval concurrent with the next fiscal year, October 1. For the open call for proposals, an LDRD Selection Committee, comprised of the Associate Laboratory Directors (ALDs) for the Scientific Directorates, an equal number of scientists recommended by the Brookhaven Council, plus the Assistant Laboratory Director for Policy and Strategic Planning, review the proposals submitted in response to the solicitation. The Open Can LDRD category emphasizes innovative research concepts with limited management filtering to encourage the creativity of individual researchers. The competition is open to all BNL staff in programmatic, scientific, engineering, and technical support areas. Researchers submit their project proposals to the Assistant Laboratory Director for Policy and Strategic Planning. A portion of the LDRD budget is held for the Strategic LDRD (S-LDRD) category. Projects in this category focus on innovative R&D activities that support the strategic agenda of the Laboratory. The Laboratory Director entertains requests or articulates the need for S-LDRD funds at any time. Strategic LDRD Proposals also undergo rigorous peer review; the approach to review is tailored to the size and scope of the proposal. These Projects are driven by special opportunities, including: (1) Research project(s) in support of Laboratory strategic initiatives as defined and articulated by the Director; (2) Research project(s) in support of a Laboratory strategic hire; (3) Evolution of Program Development activities into research and development activities; and (4) ALD proposal(s) to the Director to support unique research opportunities. The goals and objectives of BNL's LDRD Program can be inferred fronl the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. To be one of the premier DOE National Laboratories, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence and a means to address National needs within the overall mission of the DOE and BNL.« less

Identification of liver cancer-specific aptamers using whole live cells.

PubMed

Shangguan, Dihua; Meng, Ling; Cao, Zehui Charles; Xiao, Zeyu; Fang, Xiaohong; Li, Ying; Cardona, Diana; Witek, Rafal P; Liu, Chen; Tan, Weihong

2008-02-01

Liver cancer is the third most deadly cancers in the world. Unfortunately, there is no effective treatment. One of the major problems is that most cancers are diagnosed in the later stage, when surgical resection is not feasible. Thus, accurate early diagnosis would significantly improve the clinical outcome of liver cancer. Currently, there are no effective molecular probes to recognize biomarkers that are specific for liver cancer. The objective of our current study is to identify liver cancer cell-specific molecular probes that could be used for liver cancer recognition and diagnosis. We applied a newly developed cell-SELEX (Systematic Evolution of Ligands by EXponential enrichment) method for the generation of molecular probes for specific recognition of liver cancer cells. The cell-SELEX uses whole live cells as targets to select aptamers (designed DNA/RNA) for cell recognition. In generating aptamers for liver cancer recognition, two liver cell lines were used: a liver cancer cell line BNL 1ME A.7R.1 (MEAR) and a noncancer cell line, BNL CL.2 (BNL). Both cell lines were originally derived from Balb/cJ mice. Through multiple rounds of selection using BNL as a control, we have identified a panel of aptamers that specifically recognize the cancer cell line MEAR with Kd in the nanomolar range. We have also demonstrated that some of the selective aptamers could specifically bind liver cancer cells in a mouse model. There are two major new results (compared with our reported cell-SELEX methodology) in addition to the generation of aptamers specifically for liver cancer. The first one is that our current study demonstrates that cell-based aptamer selection can select specific aptamers for multiple cell lines, even for two cell lines with minor differences (MEAR cell is derived from BNL by chemical inducement); and the second result is that cell-SELEX can be used for adhesive cells and thus open the door for solid tumor selection and investigation. The newly generated cancer-specific aptamers hold great promise as molecular probes for cancer early diagnosis and basic mechanism studies.

Inhibitory effect of Styrax Japonica Siebold et al. Zuccarini glycoprotein (38 kDa) on interleukin-1β and induction proteins in chromium(VI)-treated BNL CL.2 cells.

PubMed

Lee, Jin; Lim, Kye-Taek

2012-08-01

Chromium(VI) [Cr(VI)] induces chronic inflammation in hepatocytes. Inflammation has been shown to play an important role in tumorigenesis, tumor progression, and metastasis. To examine the effects of the Styrax Japonica Siebold et al. Zuccarini (SJSZ) glycoprotein on inflammation in BNL CL.2 cells, we evaluated the activities of c-Jun NH(2)-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), nuclear factor (NF)-κB (p50 and p65), and inflammation-related factors [cyclooxygenase (COX)-2, inducible nitric oxide syntheses (iNOS) and interleukin (IL)-1β] in Cr-induced BNL CL.2 cells using immunoblot analysis and RT-PCR. We also used two-dimensional gel electrophoresis (2-DE) to compare between treatments. To determine which proteins are induced by Cr(VI), we evaluated total protein lysates using 2-DE. After Cr(VI) treatment, total protein lysates were prepared and resolved by 2-DE. The results obtained from this study demonstrated that the SJSZ glycoprotein (50 μg/ml) inhibits expression of JNK, ERK, NF-κB, and the expression of COX-2, iNOS, and IL-1β. Moreover, the results obtained from 2DE showed that four proteins out of nine proteins were relatively expressed strongly, while the rest of them were relatively appeared weakly on the gel. Taken together, these data indicate that the SJSZ glycoprotein prevents expression of COX-2, iNOS, and IL-1β by blocking NF-κB and MAPKs in Cr(VI)-induced BNL CL.2 cells.

Modulatory effect of phytoglycoprotein (38 kDa) on cyclin D1/CDK4 in BNL CL.2 cells induced by N-methyl-N'-nitro-N-nitrosoguanidine.

PubMed

Lee, Jin; Lim, Kye-Taek

2012-02-01

In the developmental stages of cancer, cell transformation occurs after the promotion stage and is a marker of cancer progression. This cell transformation is related to abnormal proliferation during the cancer initiation stage. The purpose of this study was to evaluate the effect of Styrax japonica Siebold et al. Zuccarin (SJSZ) glycoprotein on cell transformation in murine embryonic liver cells (BNL CL.2) following N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) treatment. To determine abnormal proliferation during the initiation stage, intracellular reactive oxygen species (ROS), phosphorylation of extracellular signal-regulated kinase (ERK), p38 mitogen-activated protein kinase (MAPK), activities of cell cycle-related factors [cyclin D1/cyclin dependent kinase (CDK) 4], cell cycle inhibitors (p53, p21, and p27), nuclear factor (NF)-κB, and proliferating cell nuclear antigen (PCNA) were evaluated using Western blot analysis and real-time PCR. Our study demonstrated that SJSZ glycoprotein (50 μg/ml) reduces foci formation with combined treatment [MNNG and 12-O-tetradecanoyl phorbol-13-acetate] of BNL CL.2 cells. With regard to proliferation-related signals, our finding indicated that SJSZ glycoprotein (50 μg/ml) diminished the production of intracellular ROS, activity of phosphorylated ERK, p38 MAPK, NF-κB (p50 and p65), PCNA, and cyclin D1/CDK4 in MNNG-induced BNL CL.2 cells. Taken together, these results lead us to speculate that SJSZ glycoprotein can inhibit abnormal cell proliferation at the initiation stage of hepatocarcinogenesis.

Tumor cell apoptosis induces tumor-specific immunity in a CC chemokine receptor 1- and 5-dependent manner in mice.

PubMed

Iida, Noriho; Nakamoto, Yasunari; Baba, Tomohisa; Kakinoki, Kaheita; Li, Ying-Yi; Wu, Yu; Matsushima, Kouji; Kaneko, Shuichi; Mukaida, Naofumi

2008-10-01

The first step in the generation of tumor immunity is the migration of dendritic cells (DCs) to the apoptotic tumor, which is presumed to be mediated by various chemokines. To clarify the roles of chemokines, we induced apoptosis using suicide gene therapy and investigated the immune responses following tumor apoptosis. We injected mice with a murine hepatoma cell line, BNL 1ME A.7R.1 (BNL), transfected with HSV-thymidine kinase (tk) gene and then treated the animals with ganciclovir (GCV). GCV treatment induced massive tumor cell apoptosis accompanied with intratumoral DC infiltration. Tumor-infiltrating DCs expressed chemokine receptors CCR1 and CCR5, and T cells and macrophages expressed CCL3, a ligand for CCR1 and CCR5. Moreover, tumor apoptosis increased the numbers of DCs migrating into the draining lymph nodes and eventually generated a specific cytotoxic cell population against BNL cells. Although GCV completely eradicated HSV-tk-transfected BNL cells in CCR1-, CCR5-, or CCL3-deficient mice, intratumoral and intranodal DC infiltration and the subsequent cytotoxicity generation were attenuated in these mice. When parental cells were injected again after complete eradication of primary tumors by GCV treatment, the wild-type mice completely rejected the rechallenged cells, but the deficient mice exhibited impairment in rejection. Thus, we provide definitive evidence indicating that CCR1 and CCR5 and their ligand CCL3 play a crucial role in the regulation of intratumoral DC accumulation and the subsequent establishment of tumor immunity following induction of tumor apoptosis by suicide genes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

ENGEL-COX,J.; ZIMMERMAN,E.; LEE,R.

Throughout the scientific community, Brookhaven National Laboratory (BNL) is renowned for its leading-edge research in physics, medicine, chemistry, biology, materials, and the environment. BNL is committed to supporting its world-class scientific research with an internationally recognized environmental protection program. The 1999 Site Environmental Report (SER) summarizes the status of the Laboratory's environmental programs and performance, including the steady progress towards cleaning up the site and fully integrating environmental stewardship into all facets of the Laboratory's mission. BNL is located on 5,265 acres of pine barrens in Suffolk County in the center of Long Island, New York. The Laboratory is situatedmore » above a sole source aquifer at the headwaters of the Peconic River; therefore, protecting ground and surface water quality is a special concern. Approximately 3,600 acres of the site are undeveloped and serve as habitat for a wide variety of animals and plants, including one New York State endangered species, the tiger salamander, and two New York State threatened species, the banded sunfish and the stiff goldenrod. Monitoring, preserving, and restoring these ecological resources is a high priority for the Laboratory.« less

High Frequency, High Gradient Dielectric Wakefield Acceleration Experiments at SLAC and BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenzweig, James; /UCLA; Travish, Gil

Given the recent success of >GV/m dielectric wakefield accelerator (DWA) breakdown experiments at SLAC, and follow-on coherent Cerenkov radiation production at the UCLA Neptune, a UCLA-USC-SLAC collaboration is now implementing a new set of experiments that explore various DWA scenarios. These experiments are motivated by the opportunities presented by the approval of FACET facility at SLAC, as well as unique pulse-train wakefield drivers at BNL. The SLAC experiments permit further exploration of the multi-GeV/m envelope in DWAs, and will entail investigations of novel materials (e.g. CVD diamond) and geometries (Bragg cylindrical structures, slab-symmetric DWAs), and have an over-riding goal ofmore » demonstrating >GeV acceleration in {approx}33 cm DWA tubes. In the nearer term before FACET's commissioning, we are planning measurements at the BNL ATF, in which we drive {approx}50-200 MV/m fields with single pulses or pulse trains. These experiments are of high relevance to enhancing linear collider DWA designs, as they will demonstrate potential for efficient operation with pulse trains.« less

Energy Dependence of Directed Flow over a Wide Range of Pseudorapidity in Au+Au Collisions at the BNL Relativistic Heavy Ion Collider

NASA Astrophysics Data System (ADS)

Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Hauer, M.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Seals, H.; Sedykh, I.; Skulski, W.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Tang, J.-L.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Wenger, E.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.

2006-07-01

We report on measurements of directed flow as a function of pseudorapidity in Au+Au collisions at energies of sNN=19.6, 62.4, 130 and 200 GeV as measured by the PHOBOS detector at the BNL Relativistic Heavy Ion Collider. These results are particularly valuable because of the extensive, continuous pseudorapidity coverage of the PHOBOS detector. There is no significant indication of structure near midrapidity and the data surprisingly exhibit extended longitudinal scaling similar to that seen for elliptic flow and charged particle pseudorapidity density.

BNL 56 MHz HOM damper prototype fabrication at JLAB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huque, N.; McIntyre, G.; Daly, E. F.

A prototype Higher-Order Mode (HOM) Damper was fabricated at JLab for the Relativistic Heavy-Ion Collider’s (RHIC) 56 MHz cavity at Brookhaven National Laboratory (BNL). Primarily constructed from high RRR Niobium and Sapphire, the coaxial damper presented significant challenges in electron-beam welding (EBW), brazing and machining via acid etching. The results of the prototype operation brought about changes in the damper design, due to overheating braze alloys and possible multi-pacting. Five production HOM dampers are currently being fabricated at JLab. This paper outlines the challenges faced in the fabrication process, and the solutions put in place.

BNL 56 MHz HOM Damper Prototype Fabrication at JLab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huque, Naeem A.; Daly, Edward F.; Clemens, William A.

A prototype Higher-Order Mode (HOM) Damper was fabricated at JLab for the Relativistic Heavy-Ion Collider's (RHIC) 56 MHz cavity at Brookhaven National Laboratory (BNL). Primarily constructed from high RRR Niobium and Sapphire, the coaxial damper presented significant challenges in electron-beam welding (EBW), brazing and machining via acid etching. The results of the prototype operation brought about changes in the damper design, due to overheating braze alloys and possible multi-pacting. Five production HOM dampers are currently being fabricated at JLab. This paper outlines the challenges faced in the fabrication process, and the solutions put in place.

Multi-MW accelerator target material properties under proton irradiation at Brookhaven National Laboratory linear isotope producer

DOE PAGES

Simos, N.; Ludewig, H.; Kirk, H.; ...

2018-05-29

The effects of proton beams irradiating materials considered for targets in high-power accelerator experiments have been studied using the Brookhaven National Laboratory’s (BNL) 200 MeV proton linac. A wide array of materials and alloys covering a wide range of the atomic number (Z) are being scoped by the high-power accelerator community prompting the BNL studies to focus on materials representing each distinct range, i.e. low-Z, mid-Z and high-Z. The low range includes materials such as beryllium and graphite, the midrange alloys such as Ti-6Al-4V, gum metal and super-Invar and finally the high-Z range pure tungsten and tantalum. Of interest inmore » assessing proton irradiation effects are (a) changes in physiomechanical properties which are important in maintaining high-power target functionality, (b) identification of possible limits of proton flux or fluence above which certain materials cease to maintain integrity, (c) the role of material operating temperature in inducing or maintaining radiation damage reversal, and (d) phase stability and microstructural changes. The paper presents excerpt results deduced from macroscopic and microscopic post-irradiation evaluation (PIE) following several irradiation campaigns conducted at the BNL 200 MeV linac and specifically at the isotope producer beam-line/target station. The microscopic PIE relied on high energy x-ray diffraction at the BNL NSLS X17B1 and NSLS II XPD beam lines. The studies reveal the dramatic effects of irradiation on phase stability in several of the materials, changes in physical properties and ductility loss as well as thermally induced radiation damage reversal in graphite and alloys such as super-Invar.« less

Multi-MW accelerator target material properties under proton irradiation at Brookhaven National Laboratory linear isotope producer

NASA Astrophysics Data System (ADS)

Simos, N.; Ludewig, H.; Kirk, H.; Dooryhee, E.; Ghose, S.; Zhong, Z.; Zhong, H.; Makimura, S.; Yoshimura, K.; Bennett, J. R. J.; Kotsinas, G.; Kotsina, Z.; McDonald, K. T.

2018-05-01

The effects of proton beams irradiating materials considered for targets in high-power accelerator experiments have been studied using the Brookhaven National Laboratory's (BNL) 200 MeV proton linac. A wide array of materials and alloys covering a wide range of the atomic number (Z) are being scoped by the high-power accelerator community prompting the BNL studies to focus on materials representing each distinct range, i.e. low-Z, mid-Z and high-Z. The low range includes materials such as beryllium and graphite, the midrange alloys such as Ti-6Al-4V, gum metal and super-Invar and finally the high-Z range pure tungsten and tantalum. Of interest in assessing proton irradiation effects are (a) changes in physiomechanical properties which are important in maintaining high-power target functionality, (b) identification of possible limits of proton flux or fluence above which certain materials cease to maintain integrity, (c) the role of material operating temperature in inducing or maintaining radiation damage reversal, and (d) phase stability and microstructural changes. The paper presents excerpt results deduced from macroscopic and microscopic post-irradiation evaluation (PIE) following several irradiation campaigns conducted at the BNL 200 MeV linac and specifically at the isotope producer beam-line/target station. The microscopic PIE relied on high energy x-ray diffraction at the BNL NSLS X17B1 and NSLS II XPD beam lines. The studies reveal the dramatic effects of irradiation on phase stability in several of the materials, changes in physical properties and ductility loss as well as thermally induced radiation damage reversal in graphite and alloys such as super-Invar.

Editorial

NASA Astrophysics Data System (ADS)

Hei, Tom K.

2016-06-01

Ground based radiation research facilities are indispensable for a better understanding of the biological principles governing the responses of living organisms to space radiation and for advancing our knowledge in space radiation dosimetry and protection. 2015 marked the 20th anniversary of the first acquisition of space radiation biology and physics data at the Alternating Gradient Synchrotron (AGS) at the Brookhaven National Laboratory (BNL) in Upton, New York. Use of the BNL AGS was the product of a collaborative agreement between NASA and BNL to promote the goals of NASA to "expand human presence in the solar system and to the surface of Mars and to advance exploration, science, innovation and benefits to humanity and international collaboration". This collaborative agreement signed on April 8th, 1994 built on previous work at the Lawrence Berkeley National Laboratory Bevalac and paved the way for the approval and construction of a dedicated space radiation laboratory at BNL, the NASA Space Radiation Laboratory (NSRL). In this volume we present three review articles: on the history of the creation of the NSRL, by Walter Schimmerling; on the physics-related research at the AGS and NSRL, by Jack Miller and Cary Zeitlin; and on the identification and evaluation of biomarkers for modeling cancer risk after exposure to space radiation, by Janice Pluth and her colleagues. It is the hope of the editors that our readers, and especially those relatively new to the field, will find these articles to be informative and interesting and that they will foster an appreciation of the importance of ground based radiation research in protecting the health of crew members as they venture out into the solar system in the coming decades.

Intertester reliability of the acceptable noise level.

PubMed

Gordon-Hickey, Susan; Adams, Elizabeth; Moore, Robert; Gaal, Ashley; Berry, Katie; Brock, Sommer

2012-01-01

The acceptable noise level (ANL) serves to accurately predict the listener's likelihood of success with amplification. It has been proposed as a pre-hearing aid fitting protocol for hearing aid selection and counseling purposes. The ANL is a subjective measure of the listener's ability to accept background noise. Measurement of ANL relies on the tester and listener to follow the instructions set forth. To date, no research has explored the reliability of ANL as measured across clinicians or testers. To examine the intertester reliability of ANL. A descriptive quasi-experimental reliability study was completed. ANL was measured for one group of listeners by three testers. Three participants served as testers. Each tester was familiar with basic audiometry. Twenty-five young adults with normal hearing served as listeners. Each tester was stationed in a laboratory with the needed equipment. Listeners were instructed to report to these laboratories in a random order provided by the experimenters. The testers assessed most comfortable listening level (MCL) and background noise level (BNL) for all 25 listeners. Intraclass correlation coefficients were significant and revealed that MCL, BNL, and ANLs are reliable across testers. Additionally, one-way ANOVAs for MCL, BNL, and ANL were not significant. These findings indicate that MCL, BNL, and ANL do not differ significantly when measured by different testers. If the ANL instruction set is accurately followed, ANL can be reliably measured across testers, laboratories, and clinics. Intertester reliability of ANL allows for comparison across ANLs measured by different individuals. Findings of the present study indicate that tester reliability can be ruled out as a factor contributing to the disparity of mean ANLs reported in the literature. American Academy of Audiology.

The single fgf receptor gene in the beetle Tribolium castaneum codes for two isoforms that integrate FGF8- and Branchless-dependent signals.

PubMed

Sharma, Rahul; Beer, Katharina; Iwanov, Katharina; Schmöhl, Felix; Beckmann, Paula Indigo; Schröder, Reinhard

2015-06-15

The precise regulation of cell-cell communication by numerous signal-transduction pathways is fundamental for many different processes during embryonic development. One important signalling pathway is the evolutionary conserved fibroblast-growth-factor (FGF)-pathway that controls processes like cell migration, axis specification and mesoderm formation in vertebrate and invertebrate animals. In the model insect Drosophila, the FGF ligand / receptor combinations of FGF8 (Pyramus and Thisbe) / Heartless (Htl) and Branchless (Bnl) / Breathless (Btl) are required for the migration of mesodermal cells and for the formation of the tracheal network respectively with both the receptors functioning independently of each other. However, only a single fgf-receptor gene (Tc-fgfr) has been identified in the genome of the beetle Tribolium. We therefore asked whether both the ligands Fgf8 and Bnl could transduce their signal through a common FGF-receptor in Tribolium. Indeed, we found that the function of the single Tc-fgfr gene is essential for mesoderm differentiation as well as for the formation of the tracheal network during early development. Ligand specific RNAi for Tc-fgf8 and Tc-bnl resulted in two distinct non-overlapping phenotypes of impaired mesoderm differentiation and abnormal formation of the tracheal network in Tc-fgf8- and Tc-bnl(RNAi) embryos respectively. We further show that the single Tc-fgfr gene encodes at least two different receptor isoforms that are generated through alternative splicing. We in addition demonstrate through exon-specific RNAi their distinct tissue-specific functions. Finally, we discuss the structure of the fgf-receptor gene from an evolutionary perspective. Copyright © 2015 Elsevier Inc. All rights reserved.

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 77, RBRC SCIENTIFIC REVIEW COMMITTEE MEETING, OCTOBER 10-12, 2005

DOE Office of Scientific and Technical Information (OSTI.GOV)

SAMIOS, N.P.

The eighth evaluation of the RIKEN BNL Research Center (RBRC) took place on October 10-12, 2005, at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC) were Dr. Jean-Paul Blaizot, Professor Makoto Kobayashi, Dr. Akira Masaike, Professor Charles Young Prescott (Chair), Professor Stephen Sharpe (absent), and Professor Jack Sandweiss. We are grateful to Professor Akira Ukawa who was appointed to the SRC to cover Professor Sharpe's area of expertise. In addition to reviewing this year's program, the committee, augmented by Professor Kozi Nakai, evaluated the RBRC proposal for a five-year extension of the RIKEN BNL Collaboration MOU beyondmore » 2007. Dr. Koji Kaya, Director of the Discovery Research Institute, RIKEN, Japan, presided over the session on the extension proposal. In order to illustrate the breadth and scope of the RBRC program, each member of the Center made a presentation on higher research efforts. In addition, a special session was held in connection with the RBRC QCDSP and QCDOC supercomputers. Professor Norman H. Christ, a collaborator from Columbia University, gave a presentation on the progress and status of the project, and Professor Frithjof Karsch of BNL presented the first physics results from QCDOC. Although the main purpose of this review is a report to RIKEN Management (Dr. Ryoji Noyori, RIKEN President) on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment.« less

Multi-MW accelerator target material properties under proton irradiation at Brookhaven National Laboratory linear isotope producer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simos, N.; Ludewig, H.; Kirk, H.

The effects of proton beams irradiating materials considered for targets in high-power accelerator experiments have been studied using the Brookhaven National Laboratory’s (BNL) 200 MeV proton linac. A wide array of materials and alloys covering a wide range of the atomic number (Z) are being scoped by the high-power accelerator community prompting the BNL studies to focus on materials representing each distinct range, i.e. low-Z, mid-Z and high-Z. The low range includes materials such as beryllium and graphite, the midrange alloys such as Ti-6Al-4V, gum metal and super-Invar and finally the high-Z range pure tungsten and tantalum. Of interest inmore » assessing proton irradiation effects are (a) changes in physiomechanical properties which are important in maintaining high-power target functionality, (b) identification of possible limits of proton flux or fluence above which certain materials cease to maintain integrity, (c) the role of material operating temperature in inducing or maintaining radiation damage reversal, and (d) phase stability and microstructural changes. The paper presents excerpt results deduced from macroscopic and microscopic post-irradiation evaluation (PIE) following several irradiation campaigns conducted at the BNL 200 MeV linac and specifically at the isotope producer beam-line/target station. The microscopic PIE relied on high energy x-ray diffraction at the BNL NSLS X17B1 and NSLS II XPD beam lines. The studies reveal the dramatic effects of irradiation on phase stability in several of the materials, changes in physical properties and ductility loss as well as thermally induced radiation damage reversal in graphite and alloys such as super-Invar.« less

Beam dynamics validation of the Halbach Technology FFAG Cell for Cornell-BNL Energy Recovery Linac

NASA Astrophysics Data System (ADS)

Méot, F.; Tsoupas, N.; Brooks, S.; Trbojevic, D.

2018-07-01

The Cornell-BNL Electron Test Accelerator (CBETA), a 150 MeV energy recovery linac (ERL) now in construction at Cornell, employs a fixed-field alternating gradient optics return loop: a single beam line comprised of FFAG cells, which accepts four recirculated energies. CBETA FFAG cell uses Halbach permanent magnet technology, its design studies have covered an extended period of time supported by extensive particle dynamics simulations using computed 3-D field map models. This approach is discussed, and illustrated here, based on the final stage in these beam dynamics studies, namely the validation of a ultimate, optimized design of the Halbach cell.

J/Psi production in pp collisions at square root = 200 GeV at the BNL relativistic heavy ion collider.

PubMed

Cooper, Fred; Liu, Ming X; Nayak, Gouranga C

2004-10-22

We study J/psi production in pp collisions at BNL Relativistic Heavy Ion Collider (RHIC) within the PHENIX detector acceptance range using the color singlet and color octet mechanism which are based on perturbative QCD and nonrelativistic QCD. Here we show that the color octet mechanism reproduces the RHIC data for J/psi production in pp collisions with respect to the p(T) distribution, the rapidity distribution, and the total cross section at square root = 200 GeV. The color singlet mechanism leads to a relatively small contribution to the total cross section when compared to the octet contribution.

Energy dependence of directed flow over a wide range of pseudorapidity in Au + Au collisions at the BNL Relativistic Heavy Ion Collider.

PubMed

Back, B B; Baker, M D; Ballintijn, M; Barton, D S; Betts, R R; Bickley, A A; Bindel, R; Budzanowski, A; Busza, W; Carroll, A; Chai, Z; Decowski, M P; García, E; Gburek, T; George, N; Gulbrandsen, K; Gushue, S; Halliwell, C; Hamblen, J; Hauer, M; Heintzelman, G A; Henderson, C; Hofman, D J; Hollis, R S; Hołyński, R; Holzman, B; Iordanova, A; Johnson, E; Kane, J L; Katzy, J; Khan, N; Kucewicz, W; Kulinich, P; Kuo, C M; Lin, W T; Manly, S; McLeod, D; Mignerey, A C; Nouicer, R; Olszewski, A; Pak, R; Park, I C; Pernegger, H; Reed, C; Remsberg, L P; Reuter, M; Roland, C; Roland, G; Rosenberg, L; Sagerer, J; Sarin, P; Sawicki, P; Seals, H; Sedykh, I; Skulski, W; Smith, C E; Stankiewicz, M A; Steinberg, P; Stephans, G S F; Sukhanov, A; Tang, J-L; Tonjes, M B; Trzupek, A; Vale, C; van Nieuwenhuizen, G J; Vaurynovich, S S; Verdier, R; Veres, G I; Wenger, E; Wolfs, F L H; Wosiek, B; Woźniak, K; Wuosmaa, A H; Wysłouch, B

2006-07-07

We report on measurements of directed flow as a function of pseudorapidity in Au + Au collisions at energies of square root of SNN = 19.6, 62.4, 130 and 200 GeV as measured by the PHOBOS detector at the BNL Relativistic Heavy Ion Collider. These results are particularly valuable because of the extensive, continuous pseudorapidity coverage of the PHOBOS detector. There is no significant indication of structure near midrapidity and the data surprisingly exhibit extended longitudinal scaling similar to that seen for elliptic flow and charged particle pseudorapidity density.

Effects of bulk viscosity and hadronic rescattering in heavy ion collisions at energies available at the BNL Relativistic Heavy Ion Collider and at the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

Ryu, Sangwook; Paquet, Jean-François; Shen, Chun; Denicol, Gabriel; Schenke, Björn; Jeon, Sangyong; Gale, Charles

2018-03-01

We describe ultrarelativistic heavy ion collisions at the BNL Relativistic Heavy Ion Collider and the CERN Large Hadron Collider with a hybrid model using the IP-Glasma model for the earliest stage and viscous hydrodynamics and microscopic transport for the later stages of the collision. We demonstrate that within this framework the bulk viscosity of the plasma plays an important role in describing the experimentally observed radial flow and azimuthal anisotropy simultaneously. We further investigate the dependence of observables on the temperature below which we employ the microscopic transport description.

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DEPARTMENT OF ENERGY - DECEMBER 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOX, K.J.

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE)more » annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2006.« less

International Scavenging for First Responder Guidance and Tools: IAEA Products

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stern, W.; Berthelot, L.; Bachner, K.

In fiscal years (FY) 2016 and 2017, with support from the U.S. Department of Homeland Security (DHS), Brookhaven National Laboratory (BNL) examined the International Atomic Energy Agency (IAEA) radiological emergency response and preparedness products (guidance and tools) to determine which of these products could be useful to U.S. first responders. The IAEA Incident and Emergency Centre (IEC), which is responsible for emergency preparedness and response, offers a range of tools and guidance documents for responders in recognizing, responding to, and recovering from radiation emergencies and incidents. In order to implement this project, BNL obtained all potentially relevant tools and productsmore » produced by the IAEA IEC and analyzed these materials to determine their relevance to first responders in the U.S. Subsequently, BNL organized and hosted a workshop at DHS National Urban Security Technology Laboratory (NUSTL) for U.S. first responders to examine and evaluate IAEA products to consider their applicability to the United States. This report documents and describes the First Responder Product Evaluation Workshop, and provides recommendations on potential steps the U.S. federal government could take to make IAEA guidance and tools useful to U.S. responders.« less

36 kDa glycoprotein isolated from Rhus verniciflua stokes inhibits G/GO-induced mitochondrial apoptotic signal pathways in BNL CL.2 cells.

PubMed

Lee, Sei-Jung; Oh, Phil-Sun; Lim, Kwang; Lim, Kye-Taek

2005-12-01

Rhus verniciflua Stokes is one of the medicinal plants traditionally used to heal and treat hepatic and inflammatory diseases. We found that a glycoprotein isolated from the fruit has a molecular weight of 36 kDa and consists of a carbohydrate component (38.75%) and a protein (61.25%), and that the glycoprotein has a strong scavenging activity against hydroxyl radicals without any pro-oxidant activity in the cell-free system. In glucose/glucose oxidase (G/GO)-induced BNL CL.2 cells, the results showed that Rhus verniciflua Stokes glycoprotein has dose-dependent blocking activities against G/GO-induced cytotoxicity and apoptosis, increasing the glutathione (GSH) peroxidase activity. In the activity of the mitochondrial apoptotic mediators (cytochrome c, caspases and poly(ADP-ribose)polymerase (PARP)), the glycoprotein (100 microg/ml) showed an inhibitory effect on cytochrome c release, caspase-9/3 activation, and PARP cleavage. Moreover, Rhus verniciflua Stokes glycoprotein has a stimulating effect on the nitric oxide production. Here, we speculate that this glycoprotein is one of the natural antioxidants and of the modulators of apoptotic signal pathways in BNL CL.2 cells.

Identification of QTL regions and SSR markers associated with resistance to reniform nematode in Gossypium barbadense L. accession GB713.

PubMed

Gutiérrez, Osman A; Robinson, Arin F; Jenkins, Johnie N; McCarty, Jack C; Wubben, Martin J; Callahan, Franklin E; Nichols, Robert L

2011-02-01

The identification of molecular markers that are closely linked to gene(s) in Gossypium barbadense L. accession GB713 that confer a high level of resistance to reniform nematode (RN), Rotylenchulus reniformis Linford & Oliveira, would be very useful in cotton breeding programs. Our objectives were to determine the inheritance of RN resistance in the accession GB713, to identify SSR markers linked with RN resistance QTLs, and to map these linked markers to specific chromosomes. We grew and scored plants for RN reproduction in the P(1), P(2), F(1), F(2), BC(1)P(1), and BC(1)P(2) generations from the cross of GB713 × Acala Nem-X. The generation means analysis using the six generations indicated that one or more genes were involved in the RN resistance of GB713. The interspecific F(2) population of 300 plants was genotyped with SSR molecular markers that covered most of the chromosomes of Upland cotton (G. hirsutum L.). Results showed two QTLs on chromosome 21 and one QTL on chromosome 18. One QTL on chromosome 21 was at map position 168.6 (LOD 28.0) flanked by SSR markers, BNL 1551_162 and GH 132_199 at positions 154.2 and 177.3, respectively. A second QTL on chromosome 21 was at map position 182.7 (LOD 24.6) flanked by SSR markers BNL 4011_155 and BNL 3279_106 at positions 180.6 and 184.5, respectively. Our chromosome 21 map had 61 SSR markers covering 219 cM. One QTL with smaller genetic effects was localized to chromosome 18 at map position 39.6 (LOD 4.0) and flanked by SSR markers BNL 1721_178 and BNL 569_131 at positions 27.6 and 42.9, respectively. The two QTLs on chromosome 21 had significant additive and dominance effects, which were about equal for each QTL. The QTL on chromosome 18 showed larger additive than dominance effects. Following the precedent set by the naming of the G. longicalyx Hutchinson & Lee and G. aridum [(Rose & Standley) Skovsted] sources of resistance, we suggest the usage of Ren (barb1) and Ren (barb2) to designate these QTLs on chromosome 21 and Ren (barb3) on chromosome 18.

1995 Annual epidemiologic surveillance report for Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-12-31

The US Department of Energy`s (DOE) conduct of epidemiologic surveillance provides an early warning system for health problems among workers. This program monitors illnesses and health conditions that result in an absence of five or more consecutive workdays, occupational injuries and illnesses, and disabilities and deaths among current workers. This report summarizes epidemiologic surveillance data collected from Brookhaven National Laboratory (BNL) from January 1, 1995 through December 31, 1995. The data were collected by a coordinator at BNL and submitted to the Epidemiologic Surveillance Data Center, located at Oak Ridge Institute for Science and Education, where quality control procedures andmore » data analyses were carried out.« less

RIKEN BNL Research Center

NASA Astrophysics Data System (ADS)

Samios, Nicholas

2014-09-01

Since its inception in 1997, the RIKEN BNL Research Center (RBRC) has been a major force in the realms of Spin Physics, Relativistic Heavy Ion Physics, large scale Computing Physics and the training of a new generation of extremely talented physicists. This has been accomplished through the recruitment of an outstanding non-permanent staff of Fellows and Research associates in theory and experiment. RBRC is now a mature organization that has reached a steady level in the size of scientific and support staff while at the same time retaining its vibrant youth. A brief history of the scientific accomplishments and contributions of the RBRC physicists will be presented as well as a discussion of the unique RBRC management structure.

Sequoia establishes tip-cell number in Drosophila trachea by regulating FGF levels.

PubMed

Araújo, Sofia J; Casanova, Jordi

2011-07-15

Competition and determination of leading and trailing cells during collective cell migration is a widespread phenomenon in development, wound healing and tumour invasion. Here, we analyse this issue during in vivo ganglionic branch cell migration in the Drosophila tracheal system. We identify Sequoia (Seq) as a negative transcriptional regulator of Branchless (Bnl), a Drosophila FGF homologue, and observe that modulation of Bnl levels determines how many cells will lead this migrating cluster, regardless of Notch lateral inhibition. Our results show that becoming a tip cell does not prevent others in the branch taking the same position, suggesting that leader choice does not depend only on sensing relative amounts of FGF receptor activity.

Effects of bulk viscosity and hadronic rescattering in heavy ion collisions at energies available at the BNL Relativistic Heavy Ion Collider and at the CERN Large Hadron Collider

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryu, Sangwook; Paquet, Jean-Francois; Shen, Chun

Here, we describe ultrarelativistic heavy ion collisions at the BNL Relativistic Heavy Ion Collider and the CERN Large Hadron Collider with a hybrid model using the IP-Glasma model for the earliest stage and viscous hydrodynamics and microscopic transport for the later stages of the collision. We demonstrate that within this framework the bulk viscosity of the plasma plays an important role in describing the experimentally observed radial flow and azimuthal anisotropy simultaneously. Finally, we further investigate the dependence of observables on the temperature below which we employ the microscopic transport description.

Beam dynamics validation of the Halbach Technology FFAG Cell for Cornell-BNL Energy Recovery Linac

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meot, Francois; Tsoupas, N.; Brooks, S.

The Cornell-BNL Electron Test Accelerator (CBETA), a 150 MeV energy recovery linac (ERL) now in construction at Cornell, employs a fixed-field alternating gradient optics return loop: a single beam line comprised of FFAG cells, which accepts four recirculated energies. CBETA FFAG cell uses Halbach permanent magnet technology, its design studies have covered an extended period of time supported by extensive particle dynamics simulations using computed 3-D field map models. As a result, this approach is discussed, and illustrated here, based on the final stage in these beam dynamics studies, namely the validation of a ultimate, optimized design of the Halbachmore » cell.« less

Red Hat Enterprise Virtualization - KVM-based infrastructure services at BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cortijo, D.

2011-06-14

Over the past 18 months, BNL has moved a large percentage of its Linux-based servers and services into a Red Hat Enterprise Virtualization (RHEV) environment. This presentation will address our approach to virtualization, critical decision points, and a discussion of our implementation. Specific topics will include an overview of hardware and software requirements, networking, and storage; discussion of the decision of Red Hat solution over competing products (VMWare, Xen, etc); details on some of the features of RHEV - both current and on their roadmap; Review of performance and reliability gains since deployment completion; path forward for RHEV at BNLmore » and caveats and potential problems.« less

Beam dynamics validation of the Halbach Technology FFAG Cell for Cornell-BNL Energy Recovery Linac

DOE PAGES

Meot, Francois; Tsoupas, N.; Brooks, S.; ...

2018-04-16

The Cornell-BNL Electron Test Accelerator (CBETA), a 150 MeV energy recovery linac (ERL) now in construction at Cornell, employs a fixed-field alternating gradient optics return loop: a single beam line comprised of FFAG cells, which accepts four recirculated energies. CBETA FFAG cell uses Halbach permanent magnet technology, its design studies have covered an extended period of time supported by extensive particle dynamics simulations using computed 3-D field map models. As a result, this approach is discussed, and illustrated here, based on the final stage in these beam dynamics studies, namely the validation of a ultimate, optimized design of the Halbachmore » cell.« less

Mixing HTC and HPC Workloads with HTCondor and Slurm

NASA Astrophysics Data System (ADS)

Hollowell, C.; Barnett, J.; Caramarcu, C.; Strecker-Kellogg, W.; Wong, A.; Zaytsev, A.

2017-10-01

Traditionally, the RHIC/ATLAS Computing Facility (RACF) at Brookhaven National Laboratory (BNL) has only maintained High Throughput Computing (HTC) resources for our HEP/NP user community. We’ve been using HTCondor as our batch system for many years, as this software is particularly well suited for managing HTC processor farm resources. Recently, the RACF has also begun to design/administrate some High Performance Computing (HPC) systems for a multidisciplinary user community at BNL. In this paper, we’ll discuss our experiences using HTCondor and Slurm in an HPC context, and our facility’s attempts to allow our HTC and HPC processing farms/clusters to make opportunistic use of each other’s computing resources.

Targeted Alpha Therapy: The US DOE Tri-Lab (ORNL, BNL, LANL) Research Effort to Provide Accelerator-Produced 225Ac for Radiotherapy

NASA Astrophysics Data System (ADS)

John, Kevin

2017-01-01

Targeted radiotherapy is an emerging discipline of cancer therapy that exploits the biochemical differences between normal cells and cancer cells to selectively deliver a lethal dose of radiation to cancer cells, while leaving healthy cells relatively unperturbed. A broad overview of targeted alpha therapy including isotope production methods, and associated isotope production facility needs, will be provided. A more general overview of the US Department of Energy Isotope Program's Tri-Lab (ORNL, BNL, LANL) Research Effort to Provide Accelerator-Produced 225Ac for Radiotherapy will also be presented focusing on the accelerator-production of 225Ac and final product isolation methodologies for medical applications.

Effects of bulk viscosity and hadronic rescattering in heavy ion collisions at energies available at the BNL Relativistic Heavy Ion Collider and at the CERN Large Hadron Collider

DOE PAGES

Ryu, Sangwook; Paquet, Jean-Francois; Shen, Chun; ...

2018-03-15

Here, we describe ultrarelativistic heavy ion collisions at the BNL Relativistic Heavy Ion Collider and the CERN Large Hadron Collider with a hybrid model using the IP-Glasma model for the earliest stage and viscous hydrodynamics and microscopic transport for the later stages of the collision. We demonstrate that within this framework the bulk viscosity of the plasma plays an important role in describing the experimentally observed radial flow and azimuthal anisotropy simultaneously. Finally, we further investigate the dependence of observables on the temperature below which we employ the microscopic transport description.

Accelerating hydrodynamic description of pseudorapidity density and the initial energy density in p +p , Cu + Cu, Au + Au, and Pb + Pb collisions at energies available at the BNL Relativistic Heavy Ion Collider and the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

Ze-Fang, Jiang; Chun-Bin, Yang; Csanád, Máté; Csörgő, Tamás

2018-06-01

A known class of analytic, exact, accelerating solutions of prefect relativistic hydrodynamics with longitudinal acceleration is utilized to describe results on the pseudorapidity distributions for different collision systems. These results include d N /d η measured in p +p , Cu+Cu, Au+Au, and Pb+Pb collisions at the BNL Relativistic Heavy Ion Collider and the CERN Large Hadron Collider, in a broad centrality range. Going beyond the traditional Bjorken model, from the accelerating hydrodynamic description we determine the initial energy density and other thermodynamic quantities in those collisions.

Electron-ion collider: The next QCD frontier: Understanding the glue that binds us all

DOE Office of Scientific and Technical Information (OSTI.GOV)

Accardi, A.; Albacete, J. L.; Anselmino, M.

This White Paper presents the science case of an Electron-Ion Collider (EIC), focused on the structure and interactions of gluon-dominated matter, with the intent to articulate it to the broader nuclear science community. It was commissioned by the managements of Brookhaven National Laboratory (BNL) and Thomas Jefferson National Accelerator Facility (JLab) with the objective of presenting a summary of scientific opportunities and goals of the EIC as a follow-up to the 2007 NSAC Long Range plan. This document is a culmination of a community-wide effort in nuclear science following a series of workshops on EIC physics over the past decadesmore » and, in particular, the focused ten-week program on “Gluons and quark sea at high energies” at the Institute for Nuclear Theory in Fall 2010. It contains a brief description of a few golden physics measurements along with accelerator and detector concepts required to achieve them. It has been benefited profoundly from inputs by the users’ communities of BNL and JLab. Furthermore, this White Paper offers the promise to propel the QCD science program in the US, established with the CEBAF accelerator at JLab and the RHIC collider at BNL, to the next QCD frontier.« less

Booster Applications Facility report, phase 2

NASA Astrophysics Data System (ADS)

Thieberger, P.

1991-06-01

This report summarizes studies and planning performed by Brookhaven National Laboratory (BNL) personnel at the request of NASA for the design, construction and operation of experimental areas and facilities for utilization of ion beams from the BNL Booster synchrotron particle accelerator. These facilities would be primarily utilized to simulate space radiation for radiobiological research, shielding studies and detector calibrations. The feasibility of such a project has been established, preliminary designs and cost estimates have been developed and a formal proposal can be submitted pending DOE concurrence. The main body of this report consists of the material presented by BNL during the meeting with a NASA appointed Panel on December 10 and 11, 1990. The individual speakers have provided brief summaries of their talks and explanations of their figures. In addition there are two appendices. One, contains detailed discussion of the shared mode of operation and the corresponding beam compatibility tables. The second appendix contains cost estimate details. An executive summary on budgets and schedules has been added, containing possible phased construction and outfitting scenarios and the corresponding expense and commitment profiles as well as new operational cost estimates. Material contained in the executive summary reflects the correction of some errors and new studies performed in response to the NASA Panel suggestions.

PROCEEDINGS OF RIKEN/BNL RESEARCH CENTER WORKSHOP FUTURE TRANSVERSITY MEASUREMENTS (VOLUME 29).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boer, D.; Grosse Perdekamp, M.

2001-01-02

The RIKEN-BNL Research Center workshop on ''Future Transversity Measurements'' was held at BNL from September 18-20, 2000. The main goal of the workshop was to explore future measurements of transversity distributions. This issue is of importance to the RHIC experiments, which will study polarized proton-proton collisions with great precision. One of the workshop's goals was to enhance interactions between the DIS community at HERA and the spin community at RHIC in this field. The workshop has been well received by the participants; the number of 69 registered participants demonstrates broad interest in the workshop's topics. The program contained 35 talksmore » and there was ample time for lively discussions. The program covered all recent work in the field and in addition some very elucidating educational talks were given. At the workshop the present status of the field was discussed and it has succeeded in stimulating new experimental and theoretical studies (e.g. model calculations for interference fragmentation functions (IFF), IFF analysis at DELPHI). It also functioned to focus attention on the open questions that need to be resolved for near future experiments. In general, the conclusions were optimistic, i.e. measuring the transversity functions seems to be possible, although some new experimental hurdles will have to be taken.« less

A novel protein from edible fungi Cordyceps militaris that induces apoptosis.

PubMed

Bai, Ke-Chun; Sheu, Fuu

2018-01-01

Cordyceps militaris is a dietary therapeutic fungus that is an important model species in Cordyceps research. In this study, we purified a novel protein from the fruit bodies of C. militaris and designated it as Cordyceps militaris protein (CMP). CMP has a molecular mass of 18.0 kDa and is not glycosylated. Interestingly, CMP inhibited cell viability in murine primary cells and other cell lines in a time- and dose-dependent manner. Using trypan blue staining and a lactate dehydrogenase release assay, we showed that CMP caused cell death in the murine hepatoma cell line BNL 1MEA.7R.1. Furthermore, the frequency of BNL 1MEA.7R.1 cells at the sub-G1 stage was increased by CMP. Apoptosis, as determined by Annexin V and propidium iodide analysis, indicated that CMP could mediate BNL 1MEA.7R.1 apoptosis, but not necrosis. After coincubation with CMP, a decrease in mitochondria potential was detected using 3,3'-dihexyloxacarbocyanine iodide. These results suggest that CMP is a harmful protein that induces apoptosis through a mitochondrion-dependent pathway. Stability experiments demonstrated that heat treatment and alkalization degraded CMP and further destroyed its cell-death-inducing ability, implying that cooking is necessary for food containing C. militaris. Copyright © 2017. Published by Elsevier B.V.

FGF coordinates air sac development by activation of the EGF ligand Vein through the transcription factor PntP2.

PubMed

Cruz, Josefa; Bota-Rabassedas, Neus; Franch-Marro, Xavier

2015-12-03

How several signaling pathways are coordinated to generate complex organs through regulation of tissue growth and patterning is a fundamental question in developmental biology. The larval trachea of Drosophila is composed of differentiated functional cells and groups of imaginal tracheoblasts that build the adult trachea during metamorphosis. Air sac primordium cells (ASP) are tracheal imaginal cells that form the dorsal air sacs that supply oxygen to the flight muscles of the Drosophila adult. The ASP emerges from the tracheal branch that connects to the wing disc by the activation of both Bnl-FGF/Btl and EGFR signaling pathways. Together, these pathways promote cell migration and proliferation. In this study we demonstrate that Vein (vn) is the EGF ligand responsible for the activation of the EGFR pathway in the ASP. We also find that the Bnl-FGF/Btl pathway regulates the expression of vn through the transcription factor PointedP2 (PntP2). Furthermore, we show that the FGF target gene escargot (esg) attenuates EGFR signaling at the tip cells of the developing ASP, reducing their mitotic rate to allow proper migration. Altogether, our results reveal a link between Bnl-FGF/Btl and EGFR signaling and provide novel insight into how the crosstalk of these pathways regulates migration and growth.

FGF coordinates air sac development by activation of the EGF ligand Vein through the transcription factor PntP2

PubMed Central

Cruz, Josefa; Bota-Rabassedas, Neus; Franch-Marro, Xavier

2015-01-01

How several signaling pathways are coordinated to generate complex organs through regulation of tissue growth and patterning is a fundamental question in developmental biology. The larval trachea of Drosophila is composed of differentiated functional cells and groups of imaginal tracheoblasts that build the adult trachea during metamorphosis. Air sac primordium cells (ASP) are tracheal imaginal cells that form the dorsal air sacs that supply oxygen to the flight muscles of the Drosophila adult. The ASP emerges from the tracheal branch that connects to the wing disc by the activation of both Bnl-FGF/Btl and EGFR signaling pathways. Together, these pathways promote cell migration and proliferation. In this study we demonstrate that Vein (vn) is the EGF ligand responsible for the activation of the EGFR pathway in the ASP. We also find that the Bnl-FGF/Btl pathway regulates the expression of vn through the transcription factor PointedP2 (PntP2). Furthermore, we show that the FGF target gene escargot (esg) attenuates EGFR signaling at the tip cells of the developing ASP, reducing their mitotic rate to allow proper migration. Altogether, our results reveal a link between Bnl-FGF/Btl and EGFR signaling and provide novel insight into how the crosstalk of these pathways regulates migration and growth. PMID:26632449

Electron-ion collider: The next QCD frontier: Understanding the glue that binds us all

DOE PAGES

Accardi, A.; Albacete, J. L.; Anselmino, M.; ...

2016-09-08

This White Paper presents the science case of an Electron-Ion Collider (EIC), focused on the structure and interactions of gluon-dominated matter, with the intent to articulate it to the broader nuclear science community. It was commissioned by the managements of Brookhaven National Laboratory (BNL) and Thomas Jefferson National Accelerator Facility (JLab) with the objective of presenting a summary of scientific opportunities and goals of the EIC as a follow-up to the 2007 NSAC Long Range plan. This document is a culmination of a community-wide effort in nuclear science following a series of workshops on EIC physics over the past decadesmore » and, in particular, the focused ten-week program on “Gluons and quark sea at high energies” at the Institute for Nuclear Theory in Fall 2010. It contains a brief description of a few golden physics measurements along with accelerator and detector concepts required to achieve them. It has been benefited profoundly from inputs by the users’ communities of BNL and JLab. Furthermore, this White Paper offers the promise to propel the QCD science program in the US, established with the CEBAF accelerator at JLab and the RHIC collider at BNL, to the next QCD frontier.« less

Influences of upwind emission sources and atmospheric processing on aerosol chemistry and properties at a rural location in the Northeastern U.S.

DOE PAGES

Zhou, Shan; Collier, Sonya; Xu, Jianzhong; ...

2016-05-19

Continuous real-time measurements of atmospheric aerosol with an Aerodyne high-resolution time-of-flight aerosol mass spectrometer coupled with a fast temperature-stepping thermodenuder were carried out in summer 2011 at Brookhaven National Laboratory (BNL, 40.871°N, 72.89°W) during the Department of Energy Aerosol Life Cycle Intensive Operational Period campaign. BNL was frequently downwind of emissions from the New York metropolitan area and was exposed to various combinations of anthropogenic, biogenic, and marine emissions based on air mass history. The average concentration of submicrometer aerosol (PM1) during this study was 12.6 µg m –3 with 64% of the mass being organic. Organic aerosol (OA) atmore » BNL was found to be overwhelmingly secondary, consisting of (1) a fresher, semivolatile oxygenated organic aerosol (SV-OOA; oxygen-to-carbon ratio (O/C) = 0.54; 63% of OA mass) that was strongly influenced by transported urban plumes; (2) a regional, more aged, low-volatility OOA (LV-OOA; O/C = 0.97; 29% of OA mass) influenced by aqueous-phase processing; and (3) a nitrogen-enriched OA (NOA; nitrogen-to-carbon ratio (N/C) = 0.185; 8% of OA mass) likely composed of amine salts formed from acid-base reactions in industrial emissions. Urban emissions from the New York metropolitan areas to the W and SW in particular led to elevated PM1 mass concentration and altered aerosol composition at BNL. Transported urban plumes and local biogenic emissions likely interacted to enhance secondary organic aerosol production, primarily represented by SV-OOA. Lastly, these results suggest an important role that urban anthropogenic emissions play in affecting ambient PM concentration, composition, and physical-chemical properties at rural areas in the Northeast U.S.« less

Influences of upwind emission sources and atmospheric processing on aerosol chemistry and properties at a rural location in the Northeastern U.S.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Shan; Collier, Sonya; Xu, Jianzhong

Continuous real-time measurements of atmospheric aerosol with an Aerodyne high-resolution time-of-flight aerosol mass spectrometer coupled with a fast temperature-stepping thermodenuder were carried out in summer 2011 at Brookhaven National Laboratory (BNL, 40.871°N, 72.89°W) during the Department of Energy Aerosol Life Cycle Intensive Operational Period campaign. BNL was frequently downwind of emissions from the New York metropolitan area and was exposed to various combinations of anthropogenic, biogenic, and marine emissions based on air mass history. The average concentration of submicrometer aerosol (PM1) during this study was 12.6 µg m –3 with 64% of the mass being organic. Organic aerosol (OA) atmore » BNL was found to be overwhelmingly secondary, consisting of (1) a fresher, semivolatile oxygenated organic aerosol (SV-OOA; oxygen-to-carbon ratio (O/C) = 0.54; 63% of OA mass) that was strongly influenced by transported urban plumes; (2) a regional, more aged, low-volatility OOA (LV-OOA; O/C = 0.97; 29% of OA mass) influenced by aqueous-phase processing; and (3) a nitrogen-enriched OA (NOA; nitrogen-to-carbon ratio (N/C) = 0.185; 8% of OA mass) likely composed of amine salts formed from acid-base reactions in industrial emissions. Urban emissions from the New York metropolitan areas to the W and SW in particular led to elevated PM1 mass concentration and altered aerosol composition at BNL. Transported urban plumes and local biogenic emissions likely interacted to enhance secondary organic aerosol production, primarily represented by SV-OOA. Lastly, these results suggest an important role that urban anthropogenic emissions play in affecting ambient PM concentration, composition, and physical-chemical properties at rural areas in the Northeast U.S.« less

Plant-originated glycoprotein (24 kDa) has an inhibitory effect on proliferation of BNL CL.2 cells in response to di(2-ethylhexyl)phthalate.

PubMed

Lee, Jin; Lim, Kye-Taek

2011-08-01

Di(2-ethylhexyl)phthalate (DEHP) is one of the many environmental chemicals that are widely used in polyvinyl chloride products, vinyl flooring, food packaging and infant toys. They cause cell proliferation or dysfunction of human liver. The purpose of this study is to investigate the inhibitory effect of a glycoprotein (24 kDa) isolated from Zanthoxylum piperitum DC (ZPDC) on proliferation of liver cell in the DEHP-induced BNL CL. 2 cells. [³H]-thymidine incorporation, intracellular reactive oxygen species (ROS), intracellular Ca²⁺ mobilization and activity of protein kinase C (PKC) were measured using radioactivity and fluorescence method respectively. The expression of mitogen-activated protein kinases [extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK)], activator protein (AP)-1 (c-Jun and c-Fos), proliferating cell nuclear antigen (PCNA) and cell cycle-related factors (cyclin D1/cyclin-dependent kinase [CDK] 4) were evaluated using Western blotting or electrophoretic mobility shift assay. The results in this study showed that the levels of [³H]-thymidine incorporation, intracellular ROS, intracellular Ca²⁺ mobilization and activity of PKCα were inhibited by ZPDC glycoprotein (100 µg/ml) in the DEHP-induced BNL CL. 2 cells. Also, activities of ERK, JNK and AP-1 were reduced by ZPDC glycoprotein (100 µg/ml). With regard to cell proliferation, activities of PCNA and cyclin D1/CDK4 were significantly suppressed at treatment with ZPDC glycoprotein (100 µg/ml) in the presence of DEHP. Taken together, these findings suggest that ZPDC glycoprotein significantly normalized activities of PCNA and cyclin D1/CDK4, which relate to cell proliferation factors. Thus, ZPDC glycoprotein appears to be one of the compounds derived from natural products that are able to inhibit cell proliferation in the phthalate-induced BNL CL. 2 cells. Copyright © 2011 John Wiley & Sons, Ltd.

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 57, HIGH PT PHYSICS AT RHIC, DECEMBER 2-6, 2003

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kretzer, Stefan; Venugopalan, Raju; Vogelsang, Werner

The AuAu, dAu, and pp collision modes of the RHIC collider at BNL have led to the publication of exciting high p{perpendicular} particle production data. There have also been two physics runs with polarized protons, and preliminary results on the double-spin asymmetry for pion production had been presented very recently. The ontological questions behind these measurements are fascinating: Did RHIC collisions create a Quark-Gluon-Plasma phase and did they verify the Color Glass Condensate as the high energy limit of QCD? Will the Spin Crisis finally be resolved in terms of gluon polarization and what new surprises are we yet tomore » meet for Transverse Spin? Phenomena related to sub-microscopic questions as important as these call for interpretations that are footed in solid theory. At large p{perpendicular}, perturbative concepts are legitimately expected to provide useful approaches. The corresponding hard parton dynamics are, in several ways, key to unraveling the initial or final state and collisional phase of hard scattering events in vacuum as well as in hot or cold nuclear matter. Before the advent of RHIC data, a RIKEN-BNL workshop had been held at BNL in March 1999 on ''Hard Parton Physics in High Energy Nuclear Collisions''. The 2003 workshop on ''High p{perpendicular} Physics at RHIC'' was a logical continuation of this previous workshop. It gave the opportunity to revisit the 1999 expectations in the light of what has been found in the meantime and, at the same time, to critically discuss the underlying theoretical concepts. We brought together theorists who have done seminal work on the foundations of parton phenomenology in field theory, with theorists and experimentalists who are presently working on RHIC phenomenology. The participants were both from a high-energy physics and nuclear physics background and it remains only to be said here that this chemistry worked perfectly and the workshop was a great success.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

M. P. Jensen; Giangrande, S. E.; Bartholomew, M. J.

The Radar Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory (BNL) [http://www.arm.gov/campaigns/osc2013rwpcf] campaign was scheduled to take place from 15 July 2013 through 15 July 2015 (or until shipped for the next U.S. Department of Energy Atmospheric Radiation Measurement [ARM] Climate Research Facility first Mobile Facility [AMF1] deployment). The campaign involved the deployment of the AMF1 Scintec 915 MHz Radar Wind Profiler (RWP) at BNL, in conjunction with several other ARM, BNL and National Weather Service (NWS) instruments. The two main scientific foci of the campaign were: 1) To provide profiles of the horizontal wind to be used tomore » test and validate short-term cloud advection forecasts for solar-energy applications and 2) to provide vertical profiling capabilities for the study of dynamics (i.e., vertical velocity) and hydrometeors in winter storms. This campaign was a serendipitous opportunity that arose following the deployment of the RWP at the Two-Column Aerosol Project (TCAP) campaign in Cape Cod, Massachusetts and restriction from participation in the Green Ocean Amazon 2014/15 (GoAmazon 2014/15) campaign due to radio-frequency allocation restriction for international deployments. The RWP arrived at BNL in the fall of 2013, but deployment was delayed until fall of 2014 as work/safety planning and site preparation were completed. The RWP further encountered multiple electrical failures, which eventually required several shipments of instrument power supplies and the final amplifier to the vendor to complete repairs. Data collection began in late January 2015. The operational modes of the RWP were changed such that in addition to collecting traditional profiles of the horizontal wind, a vertically pointing mode was also included for the purpose of precipitation sensing and estimation of vertical velocities. The RWP operated well until the end of the campaign in July 2015 and collected observations for more than 20 precipitation events.« less

COLOR SUPERCONDUCTIVITY, INSTANTONS AND PARITY (NON?)-CONSERVATION AT HIGH BARYON DENSITY-VOLUME 5.

DOE Office of Scientific and Technical Information (OSTI.GOV)

GYULASSY,M.

1997-11-11

This one day Riken BNL Research Center workshop was organized to follow-up on the rapidly developing theoretical work on color super-conductivity, instanton dynamics, and possible signatures of parity violation in strong interactions that was stimulated by the talk of Frank Wilczek during the Riken BNL September Symposium. The workshop was held on November 11, 1997 at the center with over 30 participants. The program consisted of four talks on theory in the morning followed by two talks in the afternoon by experimentalists and open discussion. Krishna Rajagopal (MIT) first reviewed the status of the chiral condensate calculations at high baryonmore » density within the instanton model and the percolation transition at moderate densities restoring chiral symmetry. Mark Alford (Princeton) then discussed the nature of the novel color super-conducting diquark condensates. The main result was that the largest gap on the order of 100 MeV was found for the 0{sup +} condensate, with only a tiny gap << MeV for the other possible 1{sup +}. Thomas Schaefer (INT) gave a complete overview of the instanton effects on correlators and showed independent calculations in collaboration with Shuryak (SUNY) and Velkovsky (BNL) confirming the updated results of the Wilczek group (Princeton, MIT). Yang Pang (Columbia) addressed the general question of how breaking of discrete symmetries by any condensate with suitable quantum numbers could be searched for experimentally especially at the AGS through longitudinal A polarization measurements. Nicholas Samios (BNL) reviewed the history of measurements on {Lambda} polarization and suggested specific kinematical variables for such analysis. Brian Cole (Columbia) showed recent E910 measurements of {Lambda} production at the AGS in nuclear collisions and focused on the systematic biases that must be considered when looking for small symmetry breaking effects. Lively discussions led by Robert Jaffe (MIT) focused especially on speculations on the still unknown signatures of 0{sup +} color super-conductivity which of course would not be observable via discrete symmetry breaking.« less

Brookhaven National Laboratory

MedlinePlus

... Sciences Center for Functional Nanomaterials Chemistry Condensed Matter Physics & Materials Science National Synchrotron Light Source II Sustainable ... and Technology Nonproliferation and National Security Nuclear & Particle ... Magnet RIKEN BNL ...

Simulation of 10 A electron-beam formation and collection for a high current electron-beam ion source

NASA Astrophysics Data System (ADS)

Kponou, A.; Beebe, E.; Pikin, A.; Kuznetsov, G.; Batazova, M.; Tiunov, M.

1998-02-01

Presented is a report on the development of an electron-beam ion source (EBIS) for the relativistic heavy ion collider at Brookhaven National Laboratory (BNL) which requires operating with a 10 A electron beam. This is approximately an order of magnitude higher current than in any existing EBIS device. A test stand is presently being designed and constructed where EBIS components will be tested. It will be reported in a separate paper at this conference. The design of the 10 A electron gun, drift tubes, and electron collector requires extensive computer simulations. Calculations have been performed at Novosibirsk and BNL using two different programs, SAM and EGUN. Results of these simulations will be presented.

Performance on the low charge state laser ion source in BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Okamura, M.; Alessi, J.; Beebe, E.

On March 2014, a Laser Ion Source (LIS) was commissioned which delivers high-brightness, low-charge-state heavy ions for the hadron accelerator complex in Brookhaven National Laboratory (BNL). Since then, the LIS has provided many heavy ion species successfully. The low-charge-state (mostly singly charged) beams are injected to the Electron Beam Ion Source (EBIS), where ions are then highly ionized to fit to the following accelerator’s Q/M acceptance, like Au 32+. Recently we upgraded the LIS to be able to provide two different beams into EBIS on a pulse-to-pulse basis. Now the LIS is simultaneously providing beams for both the Relativistic Heavymore » Ion Collider (RHIC) and NASA Space Radiation Laboratory (NSRL).« less

The hydrodynamic description of pseudorapidity distributions at lower energies at BNL-RHIC

NASA Astrophysics Data System (ADS)

Jiang, Zhi-Jin; Huang, Yan; Zhang, Hai-Li; Zhang, Yu

2017-04-01

The hot and dense matter produced in nucleus-nucleus collisions is supposed to expand according to unified hydrodynamics, one of the few theoretical models that can be worked out exactly. The solution is then used to formulate the rapidity distribution of charged particles frozen out from the fluid on the space-like hypersurface with a fixed temperature, T FO. A comparison is made between the theoretical predictions and the experimental measurements carried out by PHOBOS Collaboration in the Relativistic Heavy Ion Collider (RHIC) at the Brookhaven National Laboratory (BNL) in different centrality Au-Au and Cu-Cu collisions at √ {s_{ {NN}}} = 19.6 and 22.4 GeV, respectively. The theoretical results are in good accordance with experimental data.

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

NASA Astrophysics Data System (ADS)

Ikeda, S.; Kumaki, M.; Kanesue, T.; Okamura, M.

2016-02-01

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

Technical developments at the NASA Space Radiation Laboratory.

PubMed

Lowenstein, D I; Rusek, A

2007-06-01

The NASA Space Radiation Laboratory (NSRL) located at Brookhaven National Laboratory (BNL) is a center for space radiation research in both the life and physical sciences. BNL is a multidisciplinary research facility operated for the Office of Science of the US Department of Energy (DOE). The BNL scientific research portfolio supports a large and diverse science and technology program including research in nuclear and high-energy physics, material science, chemistry, biology, medial science, and nuclear safeguards and security. NSRL, in operation since July 2003, is an accelerator-based facility which provides particle beams for radiobiology and physics studies (Lowenstein in Phys Med 17(supplement 1):26-29 2001). The program focus is to measure the risks and to ameliorate the effects of radiation encountered in space, both in low earth orbit and extended missions beyond the earth. The particle beams are produced by the Booster synchrotron, an accelerator that makes up part of the injector sequence of the DOE nuclear physics program's Relativistic Heavy Ion Collider. Ion species from protons to gold are presently available, at energies ranging from <100 to >1,000 MeV/n. The NSRL facility has recently brought into operation the ability to rapidly switch species and beam energy to supply a varied spectrum onto a given specimen. A summary of past operation performance, plans for future operations and recent and planned hardware upgrades will be described.

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ikeda, S., E-mail: ikeda.s.ae@m.titech.ac.jp; Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0108; Kumaki, M.

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied.more » For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.« less

Hedgehog Is a Positive Regulator of FGF Signalling during Embryonic Tracheal Cell Migration

PubMed Central

Butí, Elisenda; Mesquita, Duarte; Araújo, Sofia J.

2014-01-01

Cell migration is a widespread and complex process that is crucial for morphogenesis and for the underlying invasion and metastasis of human cancers. During migration, cells are steered toward target sites by guidance molecules that induce cell direction and movement through complex intracellular mechanisms. The spatio-temporal regulation of the expression of these guidance molecules is of extreme importance for both normal morphogenesis and human disease. One way to achieve this precise regulation is by combinatorial inputs of different transcription factors. Here we used Drosophila melanogaster mutants with migration defects in the ganglionic branches of the tracheal system to further clarify guidance regulation during cell migration. By studying the cellular consequences of overactivated Hh signalling, using ptc mutants, we found that Hh positively regulates Bnl/FGF levels during embryonic stages. Our results show that Hh modulates cell migration non-autonomously in the tissues surrounding the action of its activity. We further demonstrate that the Hh signalling pathway regulates bnl expression via Stripe (Sr), a zinc-finger transcription factor with homology to the Early Growth Response (EGR) family of vertebrate transcription factors. We propose that Hh modulates embryonic cell migration by participating in the spatio-temporal regulation of bnl expression in a permissive mode. By doing so, we provide a molecular link between the activation of Hh signalling and increased chemotactic responses during cell migration. PMID:24651658

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory.

PubMed

Ikeda, S; Kumaki, M; Kanesue, T; Okamura, M

2016-02-01

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

Hedgehog is a positive regulator of FGF signalling during embryonic tracheal cell migration.

PubMed

Butí, Elisenda; Mesquita, Duarte; Araújo, Sofia J

2014-01-01

Cell migration is a widespread and complex process that is crucial for morphogenesis and for the underlying invasion and metastasis of human cancers. During migration, cells are steered toward target sites by guidance molecules that induce cell direction and movement through complex intracellular mechanisms. The spatio-temporal regulation of the expression of these guidance molecules is of extreme importance for both normal morphogenesis and human disease. One way to achieve this precise regulation is by combinatorial inputs of different transcription factors. Here we used Drosophila melanogaster mutants with migration defects in the ganglionic branches of the tracheal system to further clarify guidance regulation during cell migration. By studying the cellular consequences of overactivated Hh signalling, using ptc mutants, we found that Hh positively regulates Bnl/FGF levels during embryonic stages. Our results show that Hh modulates cell migration non-autonomously in the tissues surrounding the action of its activity. We further demonstrate that the Hh signalling pathway regulates bnl expression via Stripe (Sr), a zinc-finger transcription factor with homology to the Early Growth Response (EGR) family of vertebrate transcription factors. We propose that Hh modulates embryonic cell migration by participating in the spatio-temporal regulation of bnl expression in a permissive mode. By doing so, we provide a molecular link between the activation of Hh signalling and increased chemotactic responses during cell migration.

High performance visual display for HENP detectors

NASA Astrophysics Data System (ADS)

McGuigan, Michael; Smith, Gordon; Spiletic, John; Fine, Valeri; Nevski, Pavel

2001-08-01

A high end visual display for High Energy Nuclear Physics (HENP) detectors is necessary because of the sheer size and complexity of the detector. For BNL this display will be of special interest because of STAR and ATLAS. To load, rotate, query, and debug simulation code with a modern detector simply takes too long even on a powerful work station. To visualize the HENP detectors with maximal performance we have developed software with the following characteristics. We develop a visual display of HENP detectors on BNL multiprocessor visualization server at multiple level of detail. We work with general and generic detector framework consistent with ROOT, GAUDI etc, to avoid conflicting with the many graphic development groups associated with specific detectors like STAR and ATLAS. We develop advanced OpenGL features such as transparency and polarized stereoscopy. We enable collaborative viewing of detector and events by directly running the analysis in BNL stereoscopic theatre. We construct enhanced interactive control, including the ability to slice, search and mark areas of the detector. We incorporate the ability to make a high quality still image of a view of the detector and the ability to generate animations and a fly through of the detector and output these to MPEG or VRML models. We develop data compression hardware and software so that remote interactive visualization will be possible among dispersed collaborators. We obtain real time visual display for events accumulated during simulations.

234Th: 238U disequilibrium as an indicator of sediment resuspension in Thermaikos Gulf, northwestern Aegean Sea

NASA Astrophysics Data System (ADS)

Muir, G. K. P.; Pates, J. M.; Karageorgis, A. P.; Kaberi, H.

2005-12-01

234Th: 238U disequilibria have been used extensively as tracers of particle dynamics in marine environments. 234Th ( t1/2=24.1 days) can be used as "proxy" for particle reactive pollutants, due to their similar rapid rate of scavenging onto particles and subsequent removal from the water column, to the sediments. Radioactive disequilibrium can be exploited to determine the rates and time-scales of processes occurring over days to months; in this instance the residence times of dissolved and particulate species with the benthic nepheloid layer (BNL). Three sampling cruises were undertaken in Thermaikos Gulf (NW Aegean Sea) during contrasting periods, to examine the impact of natural and anthropogenic activity on sediment resuspension. September and October 2001 represented background and trawling periods, respectively; January 2002 represented a mixed period, of trawling and storms. Dissolved 234Th is scavenged actively at the BNL, in the presence of suspended particulate material (SPM), with a mean residence time of 16 days. There is a weak inverse correlation between dissolved 234Th residence time and SPM concentration in the BNL, with the shortest residence times occurring during October 2001. No relationship was observed between particulate 234Th activities and SPM concentrations, indicating that particles are rapidly removed from the system, either by sinking or advection. The mean particulate 234Th residence time is 5 days.

Target and orbit feedback simulations of a muSR beam line at BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacKay, W.; Blaskiewicz, M.; Fischer, W.

Well-polarized positive surface muons are a tool to measure the magnetic properties of materials since the precession rate of the spin can be determined from the observation of the positron directions when the muons decay. For a dc beam an ideal µSR flux for surface µ + should be about 40 kHz/mm 2. In this report we show how this flux could be achieved in a beam line using the AGS complex at BNL for a source of protons. We also determined that an orbit feedback system with a pair of thin silicon position monitors and kickers would miss themore » desired flux by at least an order of magnitude, even with perfect time resolution and no multiple scattering.« less

Proceedings of RIKEN BNL Research Center Workshop: Progress in High-pT Physics at RHIC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bazilevsky, A.; Bland, L.; Vogelsang, W.

2010-03-17

This volume archives the presentations at the RIKEN BNL Research Center workshop 'Progress in High-PT Physics at RHIC', held at BNL in March 2010. Much has been learned from high-p{sub T} physics after 10 years of RHIC operations for heavy-ion collisions, polarized proton collisions and d+Au collisions. The workshop focused on recent progress in these areas by both theory and experiment. The first morning saw review talks on the theory of RHIC high-p{sub T} physics by G. Sterman and J. Soffer, and on the experimental results by M. Tannenbaum. One of the most exciting recent results from the RHIC spinmore » program is the first observation of W bosons and their associated single-spin asymmetry. The new preliminary data were reported on the first day of our workshop, along with a theoretical perspective. There also were detailed discussions on the global analysis of polarized parton distributions, including the knowledge on gluon polarization and the impact of the W-data. The main topic of the second workshop day were single-transverse spin asymmetries and their analysis in terms of transverse-momentum dependent parton distributions. There is currently much interest in a future Drell-Yan program at RHIC, thanks to the exciting physics opportunities this would offer. This was addressed in some of the talks. There also were presentations on the latest results on transverse-spin physics from HERMES and BELLE. On the final day of the workshop, the focus shifted toward forward and small-x physics at RHIC, which has become a cornerstone of the whole RHIC program. Exciting new data were presented and discussed in terms of their possible implications for our understanding of strong color-field phenomena in QCD. In the afternoon, there were discussions of nuclear parton distributions and jet observables, among them fragmentation. The workshop was concluded with outlooks toward the near-term (LHC, JLab) and longer-term (EIC) future. The workshop has been a great success. We had excellent presentations throughout and productive discussions, which showed the importance and unique value of the RHIC high-p{sub T} program. We are grateful to all participants for coming to BNL. The support provided by the RIKEN-BNL Research Center for this workshop has been magnificent, and we are most grateful for it. We also thank Brookhaven National Laboratory and the U.S. Department of Energy for providing additional support and for the facilities to hold this workshop. Finally, sincere thanks go to Pamela Esposito for her most efficient and tireless work in organizing and running the workshop.« less

University-level Non-proliferation and Safeguards Education and Human Capital Development Activities at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bachner K. M.; Pepper, S.; Gomera, J.

BNL has offered Nuclear Nonproliferation, Safeguards and Security in the 21st Century,? referred to as NNSS, every year since 2009 for graduate students in technical and policy fields related to nuclear safeguards and nonproliferation. The course focuses on relevant policy issues, in addition to technical components, and is part of a larger NGSI short course initiative that includes separate courses that are delivered at three other national laboratories and NNSA headquarters. [SCHOLZ and ROSENTHAL] The course includes lectures from esteemed nonproliferation experts, tours of various BNL facilities and laboratories, and in-field and table-top exercises on both technical and policy subjects.more » Topics include the history of the Treaty on the Non-proliferation of Nuclear Weapons (NPT) and other relevant treaties, the history of and advances in international nuclear safeguards, current relevant political situations in countries such as Iran, Iraq, and the Democratic Peoples? Republic of Korea (DPRK), nuclear science and technology, instrumentation and techniques used for verification activities, and associated research and development. The students conduct a mock Design Information Verification (DIV) at BNL?s decommissioned Medical Research Reactor. The capstone of the course includes a series of student presentations in which students act as policy advisors and provide recommendations in response to scenarios involving a current nonproliferation related event that are prepared by the course organizers. ?The course is open to domestic and foreign students, and caters to students in, entering, or recently having completed graduate school. Interested students must complete an application and provide a resume and a statement describing their interest in the course. Eighteen to 22 students attend annually; 165 students have completed the course to date. A stipend helps to defray students? travel and subsistence expenses. In 2015, the course was shortened from three weeks to two weeks to streamline the material, standardize NGSI course length, and draw in a larger applicant pool. ?The international and interdisciplinary mix of students attending the course encourages discussions of the topics presented during the course. Information about the course is available at https://www.bnl.gov/nnsscourse/. While a complete analysis of course students has not been undertaken, BNL is aware of three individuals who worked at national laboratories after attending the NNSS course, one who worked at a national laboratory prior to attending NNSS, two who worked as federal employees after attending NNSS, three who were Nonproliferation Graduate Fellows before or after attending NNSS, and three who have participated in other NGSI activities.?Design Information Verification is an IAEA inspection activity that is implemented for the purpose of ensuring that the facility design is consistent with the declared use of a facility.« less

Nepheloid Layers: Origin and Development In A Narrow Continental Shelf (nw Portugal)

NASA Astrophysics Data System (ADS)

Oliveira, A.; Vitorino, J.; Rodrigues, A.; Jouanneau, J. M.; Weber, O.; Dias, J. A.

A general hydrographic, nephelometric and sedimentological surveying of the NW Portuguese continental shelf and slope was undertaken, under winter and spring con- ditions in order to elaborate a conceptual model of suspended sediments (nepheloid layer) dynamics. Two major situations were found: 1) Spring/Summer - with northerly winds (upwelling) and low energetic wave regime that favour the deposition of sedi- ments. The northerly winds promote offshore transport in the surface nepheloid layer (SNL) and the establishment of a seasonal thermocline allow the expansion of the SNL to the west. The SNL can reach or even cross the shelf-break (50 km from coastline). Particulate organic carbon (POC) content in this layer highlights the higher contribution of biogenic particles (average concentration of 22%); 2) Winter, with southerly winds (downwelling) and high energetic wave regime that favour mid- shelf sediments resuspension and offshore transport in the bottom nepheloid layer (BNL). In the shelf-break the BNL detached to form intermediate nepheloid layers (INL). The SNL is restricted to the inner shelf. The effect of southerly winds gener- ates shoreward Ekman transport and detains the offshore westward extension of this layer even during high river run-off periods. The POC content indicates a dominance of litogenic particles in suspension (average concentration of 8%). Over the mid- and inner-shelf the dominant resuspension mechanism is associated with surface waves (Vitorino et al., 2002). Estimates based on wave measurements at mid-shelf (86m depth) suggested that, in winter, the wave shear velocity frequently exceeds 1 cm/s, assumed as the critical shear velocity for the resuspension of the fine grained sedi- ments (34m) of the bottom cover. Storm events, such as the one observed in November 1996 easily increase the wave shear velocities over 3 cm/s, leading to the increase of the BNL thickness (20-30m) (Vitorino et al., 2002; Oliveira et al., 2002). Low-frequency currents (periods longer than about 2 days) and internal waves can also lead to the resuspension of fine bottom sediments. Shelf morphology (outer shelf re- lieves and Porto submarine canyon) and sedimentary cover can also affect both spatial and vertical development of BNL.

Atmospheric Research at BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peter Daum

2008-10-06

Brookhaven researcher Peter Daum discusses an international field experiment designed to make observations of critical components of the climate system of the southeastern Pacific. Because elements of this system are poorly understood and poorly represent

Atmospheric Research at BNL

ScienceCinema

Peter Daum

2017-12-09

Brookhaven researcher Peter Daum discusses an international field experiment designed to make observations of critical components of the climate system of the southeastern Pacific. Because elements of this system are poorly understood and poorly represent

BROOKHAVEN NATIONAL LABORATORY WILDLIFE MANAGEMENT PLAN.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NAIDU,J.R.

2002-10-22

The purpose of the Wildlife Management Plan (WMP) is to promote stewardship of the natural resources found at the Brookhaven National Laboratory (BNL), and to integrate their protection with pursuit of the Laboratory's mission.

Nuclear Decay Data in the MIRD Format

Science.gov Websites

nuclear decay and decay scheme drawings will be produced in the Medical Internal Radiation Dose (MIRD National Laboratory Report BNL-NCS-52142, February 29, 1988) More information concerning medical

CMBE v05-Implementation of a toy-model for chaos analysis of relativistic nuclear collisions at the present BNL energies

NASA Astrophysics Data System (ADS)

Grossu, I. V.; Felea, D.; Jipa, Al.; Besliu, C.; Stan, E.; Ristea, O.; Ristea, C.; Calin, M.; Esanu, T.; Bordeianu, C.; Tuturas, N.

2014-11-01

In this paper we present a new version of Chaos Many-Body Engine (CMBE) Grossu et al. (2014) [1]. Inspired by the Mean Free Path concept, we implemented a new parameter, namely the ;Mean Free Time;, which is defined as the mean time between one particle's creation and its stimulated decay. This new parameter should be understood as an effect of the nuclear environment and, as opposed to the particle lifetime, it has the advantage of not being affected by the relativistic dilation. In [2] we presented a toy-model for chaos analysis of relativistic nuclear collisions at 4.5 A GeV/c (the SKM 200 collaboration). In this work, we extended our model to 200 A GeV (the maximum BNL energy).

BROOKHAVEN NATIONAL LABORATORY INSTITUTIONAL PLAN FY2003-2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This document presents the vision for Brookhaven National Laboratory (BNL) for the next five years, and a roadmap for implementing that vision. Brookhaven is a multidisciplinary science-based laboratory operated for the U.S. Department of Energy (DOE), supported primarily by programs sponsored by the DOE's Office of Science. As the third-largest funding agency for science in the U.S., one of the DOE's goals is ''to advance basic research and the instruments of science that are the foundations for DOE's applied missions, a base for U.S. technology innovation, and a source of remarkable insights into our physical and biological world, and themore » nature of matter and energy'' (DOE Office of Science Strategic Plan, 2000 http://www.osti.gov/portfolio/science.htm). BNL shapes its vision according to this plan.« less

The magnet system of the Relativistic Heavy Ion Collider (RHIC)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greene, A.; Anerella, M.; Cozzolino, J.

1995-07-01

The Relativistic Heavy Ion Collider now under construction at Brookhaven National Laboratory (BNL) is a colliding ring accelerator to be completed in 1999. Through collisions of heavy ions it is hoped to observe the creation of matter at extremely high temperatures and densities, similar to what may have occurred in the original ``Big Bang.`` The collider rings will consist of 1740 superconducting magnet elements. Some of elements are being manufactured by industrial partners (Northrop Grumman and Everson Electric). Others are being constructed or assembled at BNL. A description is given of the magnet designs, the plan for manufacturing and testmore » results. In the manufacturing of the magnets, emphasis has been placed on uniformity of their performance and on quality. Results so far indicate that this emphasis has been very successful.« less

The magnet system of the Relativistic Heavy Ion Collider (RHIC)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greene, A.; Anerella, M.; Cozzolino, J.

1996-07-01

The Relativistic Heavy Ion Collider now under construction at Brookhaven National Laboratory (BNL) is a colliding ring accelerator to be completed in 1999. Through collisions of heavy ions it is hoped to observe the creation of matter at extremely high temperatures and densities, similar to what may have occurred in the original ``Big Bang``. The collider rings will consist of 1,740 superconducting magnet elements. Some of these elements are being manufactured by industrial partners (Northrop Grumman and Everson Electric). Others are being constructed or assembled at BNL. A description is given of the magnet designs, the plan for manufacturing andmore » test results. In the manufacturing of the magnets, emphasis has been placed on uniformity of their performance and on quality. Results so far indicate that this emphasis has been very successful.« less

Thermal considerations in the cryogenic regime for the BNL double ridge higher order mode waveguide

DOE PAGES

Ravikumar, Dhananjay K.; Than, Yatming; Xu, Wencan; ...

2017-09-06

Brookhaven National Laboratory (BNL) has proposed to build an electron ion collider (EIC) as an upgrade to the existing Relativistic Heavy Ion Collider (RHIC). One part of the new design is to use superconducting radio frequency (SRF) cavities for acceleration, which sit in a bath of superfluid helium at a temperature of 2 K. SRF cavities designed for the BNL EIC create a standing electromagnetic wave, oscillating at a fundamental frequency of 647 MHz. Interaction of the charged particle beam with the EM field in the cavity creates higher order modes (HOM) of oscillation which have adverse effects on themore » beam when allowed to propagate down the beam tube. HOM waveguides are thus designed to remove this excess energy which is then damped at room temperature. Thus, these waveguides provide a direct thermal link between room temperature and the superconducting cavities adding a static thermal load. The EM wave propagating through the warmer sections of the waveguide creates an additional dynamic thermal load. This study calculates these thermal loads, concluding that the dynamic load is small in comparison to the static load. Temperature distributions are mapped on the waveguide and the number of heat intercepts required to efficiently manage thermal loads have been determined. Additonally, a thermal radiation study has been performed and it is found that this contribution is around three orders of magnitude smaller than the static conduction and dynamic loads.« less

Thermal considerations in the cryogenic regime for the BNL double ridge higher order mode waveguide

NASA Astrophysics Data System (ADS)

Ravikumar, Dhananjay K.; Than, Yatming; Xu, Wencan; Longtin, Jon

2017-09-01

Brookhaven National Laboratory (BNL) has proposed to build an electron ion collider (EIC) as an upgrade to the existing Relativistic Heavy Ion Collider (RHIC). A part of the new design is to use superconducting radio frequency (SRF) cavities for acceleration, which sit in a bath of superfluid helium at a temperature of 2 K. SRF cavities designed for the BNL EIC create a standing electromagnetic wave, oscillating at a fundamental frequency of 647 MHz. Interaction of the charged particle beam with the EM field in the cavity creates higher order modes (HOM) of oscillation which have adverse effects on the beam when allowed to propagate down the beam tube. HOM waveguides are thus designed to remove this excess energy which is then damped at room temperature. As a result, these waveguides provide a direct thermal link between room temperature and the superconducting cavities adding a static thermal load. The EM wave propagating through the warmer sections of the waveguide creates an additional dynamic thermal load. This study calculates these thermal loads, concluding that the dynamic load is small in comparison to the static load. Temperature distributions are mapped on the waveguide and the number of heat intercepts required to efficiently manage thermal loads have been determined. In addition, a thermal radiation study has been performed and it is found that this contribution is around three orders of magnitude smaller than the static conduction and dynamic loads.

Thermal considerations in the cryogenic regime for the BNL double ridge higher order mode waveguide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ravikumar, Dhananjay K.; Than, Yatming; Xu, Wencan

Brookhaven National Laboratory (BNL) has proposed to build an electron ion collider (EIC) as an upgrade to the existing Relativistic Heavy Ion Collider (RHIC). One part of the new design is to use superconducting radio frequency (SRF) cavities for acceleration, which sit in a bath of superfluid helium at a temperature of 2 K. SRF cavities designed for the BNL EIC create a standing electromagnetic wave, oscillating at a fundamental frequency of 647 MHz. Interaction of the charged particle beam with the EM field in the cavity creates higher order modes (HOM) of oscillation which have adverse effects on themore » beam when allowed to propagate down the beam tube. HOM waveguides are thus designed to remove this excess energy which is then damped at room temperature. Thus, these waveguides provide a direct thermal link between room temperature and the superconducting cavities adding a static thermal load. The EM wave propagating through the warmer sections of the waveguide creates an additional dynamic thermal load. This study calculates these thermal loads, concluding that the dynamic load is small in comparison to the static load. Temperature distributions are mapped on the waveguide and the number of heat intercepts required to efficiently manage thermal loads have been determined. Additonally, a thermal radiation study has been performed and it is found that this contribution is around three orders of magnitude smaller than the static conduction and dynamic loads.« less

Addiction Studies with Positron Emission Tomography

ScienceCinema

Joanna Fowler

2017-12-09

Brookhaven scientist Joanna Fowler describes Positron Emission Technology (PET) research at BNL which for the past 30 years has focused in the integration of basic research in radiotracer chemistry with the tools of neuroscience to develop new scientific

Addiction Studies with Positron Emission Tomography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joanna Fowler

Brookhaven scientist Joanna Fowler describes Positron Emission Technology (PET) research at BNL which for the past 30 years has focused in the integration of basic research in radiotracer chemistry with the tools of neuroscience to develop new scientific

Polarization Studies for the eRHIC Electron Storage Ring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gianfelice-Wendt, Eliana; Tepikian, S.

A hadron/lepton collider with polarized beams has been under consideration by the scientific community since some years, in the U.S. and Europe. Among the various proposals, those by JLAB and BNL with polarized electron and proton beams are currently under closer study in the U.S. Experimenters call for the simultaneous storage of electron bunches with both spin helicity. In the BNL based Ring-Ring design, electrons are stored at top energy in a ring to be accommodated in the existing RHIC tunnel. The transversely polarized electron beam is injected into the storage ring at variable energies, between 5 and 18 GeV.more » Polarization is brought into the longitudinal direction at the IP by a couple of spin rotators. In this paper results of first studies of the attainable beam polarization level and lifetime in the storage ring at 18 GeV are presented.« less

A combined model for pseudo-rapidity distributions in Cu-Cu collisions at BNL-RHIC energies

NASA Astrophysics Data System (ADS)

Jiang, Z. J.; Wang, J.; Huang, Y.

2016-04-01

The charged particles produced in nucleus-nucleus collisions come from leading particles and those frozen out from the hot and dense matter created in collisions. The leading particles are conventionally supposed having Gaussian rapidity distributions normalized to the number of participants. The hot and dense matter is assumed to expand according to the unified hydrodynamics, a hydro model which unifies the features of Landau and Hwa-Bjorken model, and freeze out into charged particles from a time-like hypersurface with a proper time of τFO. The rapidity distribution of this part of charged particles can be derived analytically. The combined contribution from both leading particles and unified hydrodynamics is then compared against the experimental data performed by BNL-RHIC-PHOBOS Collaboration in different centrality Cu-Cu collisions at sNN = 200 and 62.4GeV, respectively. The model predictions are consistent with experimental measurements.

Proceedings of RIKEN BNL Research Center Workshop: Thermal Photons and Dileptons in Heavy-Ion Collisions. Volume 119

DOE Office of Scientific and Technical Information (OSTI.GOV)

David, G.; Rapp, R.; Ruan, L.

The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the ''Rikagaku Kenkyusho'' (RIKEN, The Institute of Physical and Chemical Research) of Japan and the U. S. Department of Energy’s Office of Science. The RBRC is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has theory, lattice gauge computing and experimental components. It is presently exploring the possibility of an astrophysics component being added to the program. The primary theme for thismore » workshop related to sharing the latest experimental and theoretical developments in area of low transverse momentum (p T) dielectron and photons. All the presentations given at the workshop are included in this proceedings, primarily as PowerPoint presentations.« less

Laser ion source activities at Brookhaven National Laboratory

DOE PAGES

Kanesue, Takeshi; Okamura, Masahiro

2015-07-31

In Brookhaven National Laboratory (BNL), we have been developing laser ion sources for diverse accelerators. Tabletop Nd:YAG lasers with up to several Joules of energy are mainly used to create ablation plasmas for stable operations. The obtained charge states depend on laser power density and target species. Two types of ion extraction schemes, Direct Plasma Injection Scheme (DPIS) and conventional static extraction, are used depending on application. We optimized and select a suitable laser irradiation condition and a beam extraction scheme to meet the requirement of the following accelerator system. We have demonstrated to accelerate more than 5 x 10more » 10 of C 6+ ions using the DPIS. We successfully commissioned low charge ion beam provider to the user facilities in BNL. As a result, to achieve higher current, higher charge state and lower emittance, further studies will continue.« less

TED KYCIA MEMORIAL SYMPOSIUM.

DOE Office of Scientific and Technical Information (OSTI.GOV)

LITTENBERG, L.; RUBINSTEIN, R.; SAMIOS, N.

2000-05-19

On the afternoon of May 19 2000, a Memorial Seminar was held in the BNL physics Large Seminar Room to honor the memory of Ted Kyeia, a prominent particle physicist who had been a member of the BNL staff for 40 years. Although it was understandably a somewhat sad occasion because Ted was no longer with us, nevertheless there was much for his colleagues and friends to celebrate in recalling the outstanding contributions that he had made in those four decades. The Seminar speakers were all people who had worked with Ted during that period; each discussed one aspect ofmore » his career, but also included anecdotes and personal reminiscences. This booklet contains the Seminar program, listing the speakers, and also copies of transparencies of the talks (and one paper which was a later expansion of a talk); sadly, not all of the personal remarks appeared on the transparencies.« less

Particle Number Concentrations for HI-SCALE Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hering, Susanne V

In support of the Holistic Interactions of Shallow Clouds, Aerosols, and Ecosystems (HI-SCALE) project to study new particle formation in the atmosphere, a pair of custom water condensation particle counters were provided to the second intensive field campaign, from mid-August through mid-September 2017, at the U.S. Department of Energy Southern Great Plains Atmospheric Radiation Measurement (ARM) Climate Research Facility observatory. These custom instruments were developed by Aerosol Dynamics, Inc. (Hering et al. 2017) to detect particles into the nanometer size range. Referred to as “versatile water condensation particle counter (vWCPC)”, they are water-based, laminar-flow condensational growth instruments whose lower particlemore » size threshold can be set based on user-selected operating temperatures. For HI-SCALE, the vWCPCs were configured to measure airborne particle number concentrations in the size range from approximately 2nm to 2μm. Both were installed in the particle sizing system operated by Chongai Kuang of Brookhaven National Laboratory (BNL). One of these was operated in parallel to a TSI Model 3776, upstream of the mobility particle sizing system, to measure total ambient particle concentrations. The airborne particle concentration data from this “total particle number vWCPC” (Ntot-vWCPC) system has been reported to the ARM database. The data are reported with one-second resolution. The second vWCPC was operated in parallel with the BNL diethylene glycol instrument to count particles downstream of a separate differential mobility size analyzer. Data from this “DMA-vWCPC” system was logged by BNL, and will eventually be provided by that laboratory.« less

Workshop on body composition in basic and clinical research and the emerging technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wielopolski, L.

A special one-day workshop was held to review the status, the need for, and the future role of BNL in the Body Composition Analysis Program (BCAP). Two speakers succinctly outlined the status and future new developments using gamma nuclear resonance technology as it applies to BCAP. Seven speakers from three institutions outlined the continued need for BCAP and presented new clinical applications of BCAP in theirs respective fields of expertise. Extensive increase in the use of surrogate instrumentation, e.g., DXA and BIA, in BCAP was recognized as a significant contributing factor to the growth in BCAP. The growing role ofmore » MRI in BCAP was also emphasized. In light of these developments BCAP at BNL, with its specialized In Vivo Neutron Activation (IVNA) facilities, was recognized as a unique user oriented resource that may serve the community hospitals in the area. Three regional large institutions expressed their desire to use these facilities. In addition, IVNA provides direct measure of the human compartments in vivo, thus providing a gold standard for the surrogate methodologies that are in use or to be developed. It was strongly felt that there is a need for a calibration center with a national stature for the different methodologies for in vivo measurements, a role that befits very well a national laboratory. This offers an exquisite justification for DOE to support this orphan technology and to develop BCAP at BNL to, 1, provide a user oriented regional resource, 2, provide a national reference laboratory, and 3, develop new advanced technologies for BCAP.« less

(BNL/DoE-hyped) ``Self-Organized-Criticality'' (SOC) is Merely Newton's(1687) Third Law of Motion F = ma REdiscovery: LONG PRE-``Bak''!!!

NASA Astrophysics Data System (ADS)

Bak, P. R. E.; Newton, I.; Siegel, Edward Carl-Ludwig

2011-03-01

"Bak"/BNL/DoE "self-organized-criticality"(SOC) usual BNL/DoE media-hype P.R spin-doctoring "show-biz" "Bush-waaa-...-aaah!!!" is manifestly-demonstrated in two distinct ways to be nothing but Newton's Third Law of Motion F = ma REdiscovery!!! PHYSICS: (1687) cross-multiplied F = ma rewritten as 1/m = a/F = OUTPUT/INPUT = EFFECT/ CAUSE = inverse-mass mechanical-susceptibility = X ("w "); X ("w ") (F.-D. theorem-equivalence /proportionality) P("w ") "noise" power-spectrum; E w ; and E (any/all media upper-limiting-speeds) m. Thus: w E m; inversion yields: 1/w 1 /E 1 /m a/F = X ("w ") P("w "); hence: F = ma dual/inverse-integral-transform is "'SOC"'s" P(w) 1 / w (1) !!! ; "PURE"-MATHS: F = ma double-integral time-series s(t) = [vot + (1/2) at (2) ] inverse/dual-integral-transform formally defines power-spectrum: P (w) = S { s (t) e [ - (iORnoi) wt ] } dt = S { [ vot + (1 / 2) at 2) ] e [ - (iORnoi) wt ] } dt = voS { te [ - (iORnoi) wt ] } dt + (1 / 2) S { [ a = / = a (t) ] e [ - (iORnoi) wt) } dt = vo (d / dw) Delta (w) + (1 / 2) [ a = / = a (t) ] (d / dw) (2) Delta (w) = vo / w (0) + (1 / 2) [ a = / = a (t) ] / w 1 : ifa = 0 , then P(w) 1 / w 0 , VS . ifa = / = a (t) = / = 0 , then P(w) 1 /w; = by physics: ``SOC'' RE-expresses F = ma!!!: ``just `a tad' late/tardy'' REdiscovery of F=ma: LONG PRE-"Bak"!!!

Reassessment of the OHZ process for the thermochemical decomposition of water. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Findl, E.; Kulesa, F.; Strickland, G.

1983-08-01

A two-step thermochemical process to sequentially produce hydrogen and oxygen from water by the use of a cation-exchanged zeolite, cycled over a temperature range of 25/sup 0/ to 600/sup 0/C, was reassessed at Brookhaven National Laboratory (BNL). Based on the work of Kasai and Bishop (Union Carbide Corp., 1976), C.C.S. Associates (CCSA) performed a preliminary plant-design study for the OHZ (oxygen-hydrogen-zeolite) process, and was responsible for a few laboratory tests of the zeolite. The results of the BNL's more detailed studies showed that although the thermochemical phenomenon is valid, it is neither practical nor a cost-effective method of producing hydrogenmore » from water. Experimental findings were based on tests of indium-exchanged mordenite zeolite (10 grams, as powder) without carrier gas. The cost reassessment, which was made without using any of BNL's experimental data, showed that the hydrogen costs projected by CCSA were low by a factor of about six (2-h cycle time). The corrected costs, $46 to 50/10/sup 6/ Btu H/sub 2/, are about twice those predicted for electrolytic hydrogen ($24/10/sup 6/ Btu). Corrected costs for a cycle time of 4 hours were $54 to 58/10/sup 6/ Btu. This reassessment, which is based on a realistic review of CCSA's preliminary process design, has shown that the corrected costs projected for OHZ hydrogen are so high that no further consideration should be given to development of the concept. 6 references, 14 figures, 6 tables.« less

Inhibitory effect of SJSZ glycoprotein (38 kDa) on expression of heat shock protein 27 and 70 in chromium (VI)-treated hepatocytes.

PubMed

Lee, Jin; Lim, Kye-Taek

2012-01-01

Chromium (VI) is as an extremely toxic chemical substance, and is also an internationally recognized human carcinogen. The principal objective of this study was to determine whether or not Styrax japonica Siebold et al. Zuccarini (SJSZ) glycoprotein prevents hepatocarcinogenesis in chromium-treated BNL CL.2 cells and ICR mice. Firstly, it was evaluated that SJSZ glycoprotein has strong antioxidant character and scavenges radicals. In an effort to assess the chemopreventive effects of SJSZ glycoprotein on hepatocarcinogenesis, ICR mice were intraperitoneally injected with chromium (10 mg/kg, BW) for 8 weeks. After sacrifice, we evaluated indicators of liver tissue damage [the activities of lactate dehydrogenase (LDH) and alanine aminotransferase (ALT), and thiobarbituric acid-reactive substances (TBARS)], antioxidative enzymes [activities of superoxide dismutase (SOD), catalase (CAT) and gluthathione peroxidase (GPx)], and initiating hepatocarcinogenic indicator [heat shock protein (HSP) 27 and 70] and protein kinase C (PKC), p38 MAPK and PCNA via biochemical methods and immunoblot analysis. The results obtained from this study demonstrated that the SJSZ glycoprotein (50 μg/ml) inhibited the production of intracellular ROS in BNL CL.2 cells. In addition, the SJSZ glycoprotein (10 mg/kg, BW) attenuated the levels of LDH, ALT, and TBARS, whereas it increased antioxidative enzymes in mouse serum. SJSZ glycoprotein attenuated the activity of HSP27, HSP70, PKC, MAPKs, and PCNA in BNL CL.2 cells and liver tissue. Taken together, our results indicate that SJSZ glycoprotein might be have a potent preventive effect against hepatocarcinogenesis induced by oxidative stress.

915-MHz Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jensen, M.; Bartholomew, M. J.; Giangrande, S.

When considering the amount of shortwave radiation incident on a photovoltaic solar array and, therefore, the amount and stability of the energy output from the system, clouds represent the greatest source of short-term (i.e., scale of minutes to hours) variability through scattering and reflection of incoming solar radiation. Providing estimates of this short-term variability is important for determining and regulating the output from large solar arrays as they connect with the larger power infrastructure. In support of the installation of a 37-MW solar array on the grounds of Brookhaven National Laboratory (BNL), a study of the impacts of clouds onmore » the output of the solar array has been undertaken. The study emphasis is on predicting the change in surface solar radiation resulting from the observed/forecast cloud field on a 5-minute time scale. At these time scales, advection of cloud elements over the solar array is of particular importance. As part of the BNL Aerosol Life Cycle Intensive Operational Period (IOP), a 915-MHz Radar Wind Profiler (RWP) was deployed to determine the profile of low-level horizontal winds and the depth of the planetary boundary layer. The initial deployment mission of the 915-MHz RWP for cloud forecasting has been expanded the deployment to provide horizontal wind measurements for estimating and constraining cloud advection speeds. A secondary focus is on the observation of dynamics and microphysics of precipitation during cold season/winter storms on Long Island. In total, the profiler was deployed at BNL for 1 year from May 2011 through May 2012.« less

915-Mhz Wind Profiler for Cloud Forecasting at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jensen, M.; Bartholomew, M. J.; Giangrande, S.

When considering the amount of shortwave radiation incident on a photovoltaic solar array and, therefore, the amount and stability of the energy output from the system, clouds represent the greatest source of short-term (i.e., scale of minutes to hours) variability through scattering and reflection of incoming solar radiation. Providing estimates of this short-term variability is important for determining and regulating the output from large solar arrays as they connect with the larger power infrastructure. In support of the installation of a 37-MW solar array on the grounds of Brookhaven National Laboratory (BNL), a study of the impacts of clouds onmore » the output of the solar array has been undertaken. The study emphasis is on predicting the change in surface solar radiation resulting from the observed/forecast cloud field on a 5-minute time scale. At these time scales, advection of cloud elements over the solar array is of particular importance. As part of the BNL Aerosol Life Cycle Intensive Operational Period (IOP), a 915-MHz Radar Wind Profiler (RWP) was deployed to determine the profile of low-level horizontal winds and the depth of the planetary boundary layer. The initial deployment mission of the 915-MHz RWP for cloud forecasting has been expanded the deployment to provide horizontal wind measurements for estimating and constraining cloud advection speeds. A secondary focus is on the observation of dynamics and microphysics of precipitation during cold season/winter storms on Long Island. In total, the profiler was deployed at BNL for 1 year from May 2011 through May 2012.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paquette, Douglas; Remien, Jason; Foley, Brian

BNL prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1B, Environment, Safety and Health Reporting. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory’s environmental performance during the calendar year in review.

BNL ATLAS Grid Computing

ScienceCinema

Michael Ernst

2017-12-09

As the sole Tier-1 computing facility for ATLAS in the United States and the largest ATLAS computing center worldwide Brookhaven provides a large portion of the overall computing resources for U.S. collaborators and serves as the central hub for storing,

Particle Tracking on the BNL Relativistic Heavy Ion Collider

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dell, G. F.

1986-08-07

Tracking studies including the effects of random multipole errors as well as the effects of random and systematic multipole errors have been made for RHIC. Initial results for operating at an off diagonal working point are discussed.

Proceedings of RIKEN BNL Research Center workwhop on RHIC spin

DOE Office of Scientific and Technical Information (OSTI.GOV)

SOFFER,J.

1999-10-06

This RHIC Spin Workshop is the 1999 annual meeting of the RHIC Spin Collaboration, and the second to be hosted at Brookhaven and sponsored by the RIKEN BNL Research Center. The previous meetings were at Brookhaven (1998), Marseille (1996), MIT in 1995, Argonne 1994, Tucson in 1991, and the Polarized Collider Workshop at Penn State in 1990. As noted last year, the Center provides a home for combined work on spin by theorists, experimenters, and accelerator physicists. This proceedings, as last year, is a compilation of 1 page summaries and 5 selected transparencies for each speaker. It is designed tomore » be available soon after the workshop is completed. Speakers are welcome to include web or other references for additional material. The RHIC spin program and RHIC are rapidly becoming reality. RHIC has completed its first commissioning run, as described here by Steve Peggs. The first Siberian Snake for spin has been completed and is being installed in RHIC. A new polarized source from KEK and Triumf with over 1 milliampere of polarized H{sup minus} is being installed, described by Anatoli Zelenski. They have had a successful test of a new polarimeter for RHIC, described by Kazu Kurita and Haixin Huang. Spin commissioning is expected next spring (2000), and the first physics run for spin is anticipated for spring 2001. The purpose of the workshop is to get everyone together about once per year and discuss goals of the spin program, progress, problems, and new ideas. They also have many separate regular forums on spin. There are spin discussion sessions every Tuesday, now organized by Naohito Saito and Werner Vogelsang. The spin discussion schedule and copies of presentations are posted on http://riksg01.rhic.bnl.gov/rsc. Speakers and other spinners are encouraged to come to BNL and to lead a discussion on your favorite idea. They also have regular polarimeter and snake meetings on alternate Thursdays, led by Bill McGahern, the lead engineer for the accelerator spin effort (Thomas Roser is the spokesperson). Waldo Mackay, the Project Manager for spin, leads a weekly accelerator meeting on spin issues on Wednesdays. Finally, Phenix, STAR, and the pp2pp Collaboration have regular collaboration meetings including spin, and spin working groups.« less

Engineered Plants Make Potential Precursor to Raw Material for Plastics

ScienceCinema

Shanklin, John

2018-06-12

In a first step toward achieving industrial-scale green production, scientists from BNL and collaborators at Dow AgroSciences report engineering a plant that produces industrially relevant levels of chemicals that could potentially be used to make plastics.

410th Brookhaven Lecture

ScienceCinema

Peter Steinberg

2017-12-09

In a lecture titled "Hotter, Denser, Faster, Smaller...and Nearly Perfect: What's the Matter at RHIC?", Steinberg discusses the basic physics of the quark-gluon plasma and BNL's Relativistic Heavy Ion Collider, with a focus on several intriguing results from RHIC's recently ended PHOBOS experiment.

Raymond Davis Jr., Solar Neutrinos, and the Solar Neutrino Problems

Science.gov Websites

Neutrinos. II. Experimental; DOE Technical Report, March 16, 1964 Search for Neutrinos from the Sun; DOE Raymond Davis Dies, BNL Newsroom, June 1, 2006 Top Some links on this page may take you to non-federal

423rd Brookhaven Lecture

ScienceCinema

Mei Bai

2017-12-09

Among other things, scientists at BNL's Relativistic Heavy Ion Collider (RHIC) are studying a fundamental question of particle physics: What is responsible for proton "spin"? Physicist Mei Bai discusses this topic at the 423rd Brookhaven Lecture, "RHIC: The Worlds First High-Energy, Polarized-Proton Collider."

Neutron Data Compilation Centre, European Nuclear Energy Agency, Newsletter No. 8 Bulletin

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1969-03-15

An index to the BNL/CCDN computerized file on neutron data was made and published as CCDN-NW/4. This publication is a new presentation of this index, which describes the content of the data file at March 1969.

Miniature 'Wearable' PET Scanner Ready for Use

ScienceCinema

Vaska, Paul

2017-12-27

Scientists from BNL, Stony Brook University, and collaborators have demonstrated the efficacy of a "wearable" portable PET scanner they've developed for rats. The device will give neuroscientists a new tool for simultaneously studying brain function and behavior in fully awake, moving animals.

PROCEEDING OF THE SEEDED X-RAY FREE ELECTRON LASER WORKSHOP.

DOE Office of Scientific and Technical Information (OSTI.GOV)

WANG,X.J.; MURPHY,J.B.; YU,L.H.

2002-12-13

The underlying theory of a high gain free electron laser (FEL) has existed for two decades [1-2], but it is only in the last few years that these novel radiation sources have been realized experimentally. Several high gain FELs have successfully reached saturation in the infrared, visible and the VUV portion of the spectrum: the High Gain Harmonic Generation (HGHG) free electron lasers [3] at BNL and the Self Amplified Spontaneous Emission (SASE) FELs at LEUTL, VISA and TTF [4-6]. The outstanding challenges for future FELs are to extend high gain FELs to the X-ray regime, improve the longitudinal coherencemore » of the radiation using seeded FEL schemes and generate ultrashort pulses (<100 fs). The National Synchrotron Light Source (NSLS) of the Brookhaven National Laboratory (BNL) sponsored a Seeded X-ray Free Electron Laser Workshop on December 13-14, 2002 to explore these challenging issues. Representatives from BNL, DESY, LBNL, SLAC and UCLA made presentations on the novel schemes under consideration at their laboratories. Workshop participants had a lively discussion on the feasibility, performance and R&D issues associated with the seeded XFEL schemes. An improvement of the electron beam quality will certainly be necessary to drive the XFEL. Self-seeding SASE, cascaded HGHG, and SASE pulse compression FELs show the most promise for producing short pulse X-rays. Of these, only the self-seeded and HGHG schemes generate longitudinally coherent radiation. While the pulse length in the self-seeded scheme is determined by the electron bunch length ({approx}100 fs), the pulse length in the HGHG scheme is determined by the short pulse seed laser, and so can be much shorter ({approx} 20 fs).« less

Recent results in relativistic heavy ion collisions: from 'a new state of matter' to 'the perfect fluid'

NASA Astrophysics Data System (ADS)

Tannenbaum, M. J.

2006-07-01

Experimental physics with relativistic heavy ions dates from 1992 when a beam of 197Au of energy greater than 10 A GeV/c first became available at the Alternating Gradient Synchrotron at Brookhaven National Laboratory (BNL) soon followed in 1994 by a 208Pb beam of 158A GeV/c at the Super Proton Synchrotron at CERN (European Center for Nuclear Research). Previous pioneering measurements at the Berkeley Bevalac (Gutbrod et al 1989 Rep. Prog. Phys. 52 1267-132) in the late 1970s and early 1980s were at much lower bombarding energies (<~1A GeV/c) where nuclear breakup rather than particle production is the dominant inelastic process in A+A collisions. More recently, starting in 2000, the relativistic heavy ion collider at BNL has produced head-on collisions of two 100 A GeV beams of fully stripped Au ions, corresponding to nucleon-nucleon centre-of-mass (cm) energy, \\sqrt{s_NN}=200\\,GeV , total cm energy 200 A GeV. The objective of this research program is to produce nuclear matter with extreme density and temperature, possibly resulting in a state of matter where the quarks and gluons normally confined inside individual nucleons (r < 1 fm) are free to act over distances an order of magnitude larger. Progress from the period 1992 to the present will be reviewed, with reference to previous results from light ion and proton-proton collisions where appropriate. Emphasis will be placed on the measurements which formed the basis for the announcements by the two major laboratories: 'A new state of matter', by CERN on Febraury 10 2000 and 'The perfect fluid' by BNL on April 19 2005.

Properties of plastic tapes for cryogenic power cable insulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muller, A C

1978-01-01

A superconducting ac power transmission cable is under development at Brookhaven National Laboratory (BNL). This project was undertaken in 1972 in response to growing national power requirements. The goal of this program is to develop an underground power transmission system suitable for transferring bulk quantities of electricity over distances of 16 to 160 km. Both the capital investment and operating costs must be low enough to make the system attractive to the electric utilities. The superconducting cable shares the advantages with conventional underground cables of needing only a few feet of right-of-way width rather than the large tracts of increasinglymore » expensive land required for conventional aerial transmission. Recent cost analysis studies show that superconducting cables, although more expensive than aerial transmission, will probably be competitive with other methods of underground transmission at loads greater than 2000 MVA. Initial design studies showed that a flexible, forced-cooled cable offered the best combination of technical and economic features. A helium cooled cable with Nb/sub 3/Sn superconductor was chosen as the BNL design. The present goal of the BNL program is the construction of a 100 meter outdoor three-phase ac cable rated at 138 kV and 1000 MVA. The refrigerator and the 100 m-long dewar are already installed. Terminations and cables are under design, and it is planned to begin installation of the first single phase cable in 1979. If the results on this model show promise for eventual commercial use, cables of higher voltage and power rating will be developed. One fundamental phase of this project; the development of the required insulating materials, is described.« less

Eleventh international CODATA conference, scientific and technical data in a new era, Karlsruhe, Federal Republic of Germany, 26--29 September 1988: Foreign trip report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tichler, J.L.

Information on release of radioactive materials in airborne and liquid effluents, solid waste shipments and selected operating information from commercial nuclear power plants in the United States is maintained in a computer data base at Brookhaven National Laboratory (BNL) for the United States Nuclear Regulatory Commission (USNRC). The information entered into the data base is obtained from semiannual reports submitted by the operators of the plants to the USNRC in compliance with the USNRC Regulatory Guide 1.21, ''Measuring, Evaluating, and Reporting Radioactivity in Solid Wastes and Releases of Radioactive Materials in Liquid and Gaseous Effluents from Light-Water-Cooled Nuclear Power Plants.''more » The data on releases in the calendar year 1986 include information from 69 plants representing 87 reactors and contain approximately 19,000 entries. Since all the information is contained in a computer data base management system, entry and rapidly respond to inquiries about the data set and to generate computer readable subsets of the data. Such a subset is used as input to the computer program which generates the annual report, ''Population Dose Commitments Due to Radioactive Releases from Nuclear Power Plant Sites,'' prepared by Pacific Northwest Laboratory for the USNRC. BNL began maintaining this data base for the USNRC with the 1978 information and has added information to the data base for each succeeding year. An annual report summarizing the information for each year, prepared by BNL, and published by the USNRC, is available to the general public. Prior to 1978, annual reports were prepared by the USNRC and are available for the years 1972--1977; however, the information for these years is not in a computer accessible data base.« less

PROCEEDINGS OF THE 1999 OIL HEAT TECHNOLOGY CONFERENCE AND WORKSHOP.

DOE Office of Scientific and Technical Information (OSTI.GOV)

MCDONALD,R.J.

1999-04-01

The 1999 Oil Heat Technology Conference and Workshop, April 15-16 at Brookhaven National Laboratory (BNL) is sponsored by the U. S. Department of Energy, Office of Building Technology, State and Community Programs (DOEBTS). The meeting is also co-sponsored by the: Petroleum Marketers Association of America, New England Fuel Institute, Oilheat Manufacturers Association, National Association of Oil Heat Service Managers, New York State Energy Research and Development Authority, Empire State Petroleum Association, New York Oil Heating Association, Oil Heat Institute of Long Island, and the Pennsylvania Petroleum Association. BNL is proud to acknowledge all of our 1999 co-sponsors, without their helpmore » and support the conference would have been canceled due to budget restrictions. It is quite gratifying to see an industry come together to help support an activity like the technology conference, for the benefit of the industry as a whole. The 1999 Oil Heat Technology Conference and Workshop, will be the thirteenth since 1984, is a very valuable technology transfer activity supported by the ongoing Combustion Equipment Technology (Oilheat R and D) program at BNL. The foremost reason for the conference is to provide a platform for the exchange of information and perspectives among international researchers, engineers, manufacturers, service technicians, and marketers of oil-fired space-conditioning equipment. They will provide a conduit by which information and ideas can be exchanged to examine present technologies, as well as helping to develop the future course for oil heating advancement. These conferences also serve as a stage for unifying government representatives, researchers, fuel oil marketers, and other members of the oil-heat industry in addressing technology advancements in this important energy use sector.« less

Demonstration of the BNL Continuous Dual Trap Analyzer to Detect Perfluorocarbon Tracers for the Tag, Track and Location Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heiser,J.H.; Adams, J.; Dietz, R..

2008-10-07

The Tag, Track and Location System (TTL) Program is investigating methods of tracking an asset using perfluorocarbon tracers (PFT). The success of any TTL method requires sound detection/location instrumentation. Tracer Detection Technologies Corp (TDT), through a contract with the Office of Naval Research (ONR), is investigating different detection systems. The detections systems generally fall into two categories; proximity detectors and standoff detectors. Proximity detectors, as the name implies, need to be in close proximity (e.g., meter to 10's of meters) to the PFT source. Standoff detection searches for the PFT from a greater distance away from the source (e.g., 100'smore » of meters to kilometers). Gas Chromatographs (GC) are generally considered a proximity detection systems, but in the case of PFTs should be considered for both proximity and standoff detection with the caveat that in standoff use the GC needs to be somewhere in the PFT plume, i.e., generally downwind of the source. With a properly sized PFT source, the right GC can afford fairly large standoff (distance from the source) distances; 100's of meters to kilometers downwind. Brookhaven National Laboratory (BNL) has such a GC system and offered to demonstrate the CDTA for TTL as a no cost addition to the TDTTTL project, of which BNL was a participant. BNL is a leading authority on the sampling, collection, release and detection of PFTs. In addition, the BNL team has extensive background in atmospheric dispersion, the application of PFTs to such studies and the development of applications utilizing PFTs such as building infiltration measurements, control room integrity determination, leak location and environmental investigations. This experience and expertise is essential in developing any PFT application were dispersion, dilution and overcoming environmental conditions and interferences are integral to success. BNL has developed sophisticated gas chromatography methods and instruments that allow detection of up to seven PFTs at part per quadrillion levels (1015) with sample times as short as 60 seconds. The Continuous Dual-Trap Analyzer (CDTA) was developed for leak hunting applications and can continuously sample the air for PFTs without interruption. Sample time can be as short as 60 seconds. The CDTA has been extensively used in the commercial sector to detect PFTs that have been introduced to leaking buried dielectric fluid-filled cables or leaking subsurface gas lines. The PFTs travel through the cable or pipe until they reach the leak site. PFTs then escape into the surrounding soil and permeate/diffuse to the surface where they can be detected with the CDTA. Typically a cable is tagged with ppm levels of PFTs resulting in ppt to ppq concentrations in the air at the leak site. The CDTA is proven to be rugged, reliable and has a proven track record of successful leak location. The application of the CDTA to PFT detection for TTL is identical to application for leak detection. The CDTA operator has a general idea, with a few miles of roadway, where the leak is located, but no specific knowledge of the location (it can be any where along the road). The CDTA is mounted in a Chevy Astro Van and is dispatched to the field. In the field the van is driven at nominally 15 mph along the road. The CDTA continuously samples the air outside the van (via a 1/4-inch plastic sample tube stuck out a side window) until a positive detection occurs. The van then covers the road section where the detection occurred at a slightly slower pace to pin-point the area where the leak is and to direct soil probe samples. The soil probe samples take soil gas samples every 10 yards or so and the samples are analyzed on the CDTA. The leak can be located to within a few feet in 95% of the cases. To date the CDTA has been successful in every leak hunt performed by BNL. One interesting case was a leak hunt that resulted in repeated negative detections. The confidence in the CDTA forced the utility to recheck its 'plumbing' which lead to the discovery that a valve was turned that shouldn't have been so that gas was being diverted rather than leaking (the pressure drop was due to this diversion of the gas to another line). For TTL application, a tagged item or person is known to be in a general area and can be located by detecting the PFT emanating from the tagging source. The CDTA can be deployed in the area and by sampling in a grid fashion (starting on the downwind side of the area of interest) can easily find even very small sources. The CDTA is a perfect match for this application and the leak hunt use basically a simulation of Track and Locate. No other PFT detection technology has the detection sensitivity, proven track record and ruggedness of the CDTA. For these reasons, BNL offered to demonstrate the CDTA for TTL as a no cost addition to the TTL lidar demonstration project. This report details the demonstration scenario and results.« less

Laboratory Directed Research and Development Program Assessment for FY 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, Diane; Flynn, Liz

2017-03-31

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C, and this report fulfills that requirement.

Acquisition, use, and archiving of real-time data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leach, M.J.; Bernstein, H.J.; Tichler, J.L.

Meteorological information is needed by scientific personnel at Brookhaven National Laboratory (BNL) for various purposes. An automated system, used to acquire, archive, and provide users with weather data, is described. Hardware, software, and some of the examples of the uses of the system are detailed.

Laboratory Directed Research and Development Program Assessment for FY 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Jack; Flynn, Liz

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2C. This report fulfills that requirement.

Physiologic correlates to background noise acceptance

NASA Astrophysics Data System (ADS)

Tampas, Joanna; Harkrider, Ashley; Nabelek, Anna

2004-05-01

Acceptance of background noise can be evaluated by having listeners indicate the highest background noise level (BNL) they are willing to accept while following the words of a story presented at their most comfortable listening level (MCL). The difference between the selected MCL and BNL is termed the acceptable noise level (ANL). One of the consistent findings in previous studies of ANL is large intersubject variability in acceptance of background noise. This variability is not related to age, gender, hearing sensitivity, personality, type of background noise, or speech perception in noise performance. The purpose of the current experiment was to determine if individual differences in physiological activity measured from the peripheral and central auditory systems of young female adults with normal hearing can account for the variability observed in ANL. Correlations between ANL and various physiological responses, including spontaneous, click-evoked, and distortion-product otoacoustic emissions, auditory brainstem and middle latency evoked potentials, and electroencephalography will be presented. Results may increase understanding of the regions of the auditory system that contribute to individual noise acceptance.

COMMITTEES: SQM2008-International Conference on Strangeness in Quark Matter SQM2008-International Conference on Strangeness in Quark Matter

NASA Astrophysics Data System (ADS)

2008-04-01

Local Organising Committee Xiangzhou Cai (SINPA) Weiqin Chao (CCAST) Liewen Chen (SJTU) Jianping Cheng (Tsinghua University) Jinghua Fu (CCNU) Yuanning Gao (Tsinghua University) Xiaomei Li (CIAE) Zuotang Liang (Shandong University) Feng Liu (CCNU), Co-chair Yuxin Liu (PKU) Qing Wang (Tsinghua University) Qun Wang (USTC) Hushan Xu (IMP) Daicui Zhou (CCNU) Pengfei Zhuang (Tsinghua University), Co-chair Bingsong Zou (IHEP) International Advisory Committee Jörg Aichelin, Nantes Federico Antinori, Padova Tamás Biró, Budapest Peter Braun-Munzinger, GSI Jean Cleymans, Cape Town László Csernai, Bergen Timothy Hallman, BNL Huan Zhong Huang, UCLA Takeshi Kodama, Rio de Janeiro Carlos Lourenço, CERN Yu-Gang Ma, Shanghai Jes Masden, Aarhus Yasuo Miake, Tsukuba Berndt Müller, Duke Grazyna Odyniec, LBNL Helmut Oeschler, Darmstadt Johann Rafelski, Arizona Hans Georg Ritter, LBNL Karel Šafařík, CERN Jack Sandweiss, Yale George S F Stephans, MIT Horst Stöcker, Frankfurt Thomas Ullrich, BNL Nu Xu, LBNL William A Zajc, Columbia

DEVELOPMENT, INSTALLATION AND OPERATION OF THE MPC&A OPERATIONS MONITORING (MOM) SYSTEM AT THE JOINT INSTITUTE FOR NUCLEAR RESEARCH (JINR) DUBNA, RUSSIA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kartashov,V.V.; Pratt,W.; Romanov, Y.A.

The Material Protection, Control and Accounting (MPC&A) Operations Monitoring (MOM) systems handling at the International Intergovernmental Organization - Joint Institute for Nuclear Research (JINR) is described in this paper. Category I nuclear material (plutonium and uranium) is used in JINR research reactors, facilities and for scientific and research activities. A monitoring system (MOM) was installed at JINR in April 2003. The system design was based on a vulnerability analysis, which took into account the specifics of the Institute. The design and installation of the MOM system was a collaborative effort between JINR, Brookhaven National Laboratory (BNL) and the U.S. Departmentmore » of Energy (DOE). Financial support was provided by DOE through BNL. The installed MOM system provides facility management with additional assurance that operations involving nuclear material (NM) are correctly followed by the facility personnel. The MOM system also provides additional confidence that the MPC&A systems continue to perform effectively.« less

AFCI-2.0 Library of Neutron Cross Section Covariances

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herman, M.; Herman,M.; Oblozinsky,P.

2011-06-26

Neutron cross section covariance library has been under development by BNL-LANL collaborative effort over the last three years. The primary purpose of the library is to provide covariances for the Advanced Fuel Cycle Initiative (AFCI) data adjustment project, which is focusing on the needs of fast advanced burner reactors. The covariances refer to central values given in the 2006 release of the U.S. neutron evaluated library ENDF/B-VII. The preliminary version (AFCI-2.0beta) has been completed in October 2010 and made available to the users for comments. In the final 2.0 release, covariances for a few materials were updated, in particular newmore » LANL evaluations for {sup 238,240}Pu and {sup 241}Am were adopted. BNL was responsible for covariances for structural materials and fission products, management of the library and coordination of the work, while LANL was in charge of covariances for light nuclei and for actinides.« less

Performances of BNL high-intensity synchrotrons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weng, W.T.

1998-03-01

The AGS proton synchrotron was completed in 1960 with initial intensity in the 10 to the 10th power proton per pulse (ppp) range. Over the years, through many upgrades and improvements, the AGS now reached an intensity record of 6.3 {times} 10{sup 13} ppp, the highest world intensity record for a proton synchrotron on a single pulse basis. At the same time, the Booster reached 2.2 {times} 10{sup 13} ppp surpassing the design goal of 1.5 {times} 10{sup 13} ppp due to the introduction of second harmonic cavity during injection. The intensity limitation caused by space charge tune spread andmore » its relationship to injection energy at 50 MeV, 200 MeV, and 1,500 MeV will be presented as well as many critical accelerator manipulations. BNL currently participates in the design of an accumulator ring for the SNS project at Oak Ridge. The status on the issues of halo formation, beam losses and collimation are also presented.« less

ATOM-ECONOMICAL PATHWAYS TO METHANOL FUEL CELL FROM BIOMASS

DOE Office of Scientific and Technical Information (OSTI.GOV)

MAHAJAN,D.; WEGRZYN,J.E.

1999-03-01

An economical production of alcohol fuels from biomass, a feedstock low in carbon and high in water content, is of interest. At Brookhaven National Laboratory (BNL), a Liquid Phase Low Temperature (LPLT) concept is under development to improve the economics by maximizing the conversion of energy carrier atoms (C,H) into energy liquids (fuel). So far, the LPLT concept has been successfully applied to obtain highly efficient methanol synthesis. This synthesis was achieved with specifically designed soluble catalysts, at temperatures < 150 C. A subsequent study at BNL yielded a water-gas-shift (WGS) catalyst for the production of hydrogen from a feedstockmore » of carbon monoxide and H{sub 2}O at temperatures < 120 C. With these LPLT technologies as a background, this paper extends the discussion of the LPLT concept to include methanol decomposition into 3 moles of H{sub 2} per mole of methanol. The implication of these technologies for the atom-economical pathways to methanol fuel cell from biomass is discussed.« less

Cytoprotective effect of polysaccharide isolated from different mushrooms against 7-ketocholesterol induced damage in mouse liver cell line (BNL CL. 2).

PubMed

Kim, Joo-Shin; Chung, Hau Yin; Na, Keun

2007-01-01

Cytoprotective ability of polysaccharides isolated from different edible mushrooms was investigated on the 7-ketocholesterol-induced damaged cell line. Polysaccharide extracts from six different edible mushrooms-Flammulina velutipes, Peurotus ostreatus, Lentinus edodes, Agrocybe aegerita, Agaricus blazei, and Cordyceps militaris- were prepared by hot water extraction and alcohol precipitation. Cytoprotective ability was evaluated by measuring the viable cells of the normal embryonic liver cell line (BNL CL. 2) in the presence of 7-ketocholesterol. At 80 microg/mL of 7-ketocholesterol, cytotoxicity was very high with a loss of 98% of viable cells after 20 h of incubation. With the addition of 200 microg/mL of each polysaccharide isolate to the cell line containing 80 microg/mL of 7-ketocholesterol, polysaccharide isolates from both Flammulina velutipes and Peurotus ostreatus could significantly inhibit the 7-ketochoelsterol-induced cytotoxicity in the cells. But other polysaccharide isolates were not effective in inhibiting cell damage caused by the oxLDL-induced cytotoxicity.

Unveiling the proton spin decomposition at a future electron-ion collider

DOE PAGES

Aschenauer, Elke C.; Sassot, Rodolfo; Stratmann, Marco

2015-11-24

We present a detailed assessment of how well a future electron-ion collider could constrain helicity parton distributions in the nucleon and, therefore, unveil the role of the intrinsic spin of quarks and gluons in the proton’s spin budget. Any remaining deficit in this decomposition will provide the best indirect constraint on the contribution due to the total orbital angular momenta of quarks and gluons. Specifically, all our studies are performed in the context of global QCD analyses based on realistic pseudodata and in the light of the most recent data obtained from polarized proton-proton collisions at BNL-RHIC that have providedmore » evidence for a significant gluon polarization in the accessible, albeit limited range of momentum fractions. We also present projections on what can be achieved on the gluon’s helicity distribution by the end of BNL-RHIC operations. As a result, all estimates of current and projected uncertainties are performed with the robust Lagrange multiplier technique.« less

Discovering local order parameters in liquid water using machine learning

NASA Astrophysics Data System (ADS)

Soto, Adrian; Lu, Deyu; Yoo, Shinjae; Fernandez-Serra, Marivi

The local arrangement of water molecules in liquid phase is still being discussed and questioned. The prevailing view is that water is composed of a mixture of two structurally different liquids. One of the main challenges has been to find order parameters that are able to discriminate the complex structures of these distinct molecular environments. Several local order parameters have been proposed and studied in all sorts of atomistic simulations of liquid water but, to date, none has been able to capture the predicted dual character. This presents an ideal problem to treat with methods capable of unveiling information from complex data. In this talk we will discuss how local order parameters can be constructed from molecular dynamics trajectories by using machine learning and other related techniques. Work was partially supported by DOE Award No. DE-FG02-09ER16052, by DOE Early Career Award No. DE-SC0003871, by BNL LDRD 16-039 project and BNL Contract No. DE-SC0012704.

Cytoprotective effect of polysaccharide isolated from different mushrooms against 7-ketocholesterol induced damage in mouse liver cell line (BNL CL. 2)

PubMed Central

Chung, Hau Yin; Na, Keun

2007-01-01

Cytoprotective ability of polysaccharides isolated from different edible mushrooms was investigated on the 7-ketocholesterol-induced damaged cell line. Polysaccharide extracts from six different edible mushrooms-Flammulina velutipes, Peurotus ostreatus, Lentinus edodes, Agrocybe aegerita, Agaricus blazei, and Cordyceps militaris- were prepared by hot water extraction and alcohol precipitation. Cytoprotective ability was evaluated by measuring the viable cells of the normal embryonic liver cell line (BNL CL. 2) in the presence of 7-ketocholesterol. At 80 µg/mL of 7-ketocholesterol, cytotoxicity was very high with a loss of 98% of viable cells after 20 h of incubation. With the addition of 200 µg/mL of each polysaccharide isolate to the cell line containing 80 µg/mL of 7-ketocholesterol, polysaccharide isolates from both Flammulina velutipes and Peurotus ostreatus could significantly inhibit the 7-ketochoelsterol-induced cytotoxicity in the cells. But other polysaccharide isolates were not effective in inhibiting cell damage caused by the oxLDL-induced cytotoxicity. PMID:20368935

Oxidizing and Scavenging Characteristics of April Rains - OSCAR data report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benkovitz, C.M.; Evans, V.A.; Tichler, J.L.

The organization of this report is as follows: Chapter 1 presents a description of the OSCAR experiment, including its objectives, design, and field deployment. Chapter 2 presents the OSCAR Central Data Coordination function and summarizes the tasks needed to compile each data set. Chapters 3 through 6 address each of the four OSCAR events. A synoptic description of each event is presented in these chapters, followed by a summary of the data captured during the event. Chapter 3 and Appendices C-G then present detailed tabular and graphical displays of the data captured during this event by the intermediate-density precipitation chemistrymore » network, the BNL aircraft and the surface air chemistry measurements conducted by BNL and by state/province agency networks. Data from the high-density precipitation chemistry network are being presented in a separate series of reports by Pacific Northwest Laboratory. Detailed displays of the data for events 2 to 4 have not been included in this report; however, selected portions could be developed for interested parties.« less

Epidemiologic surveillance. [1994] amended annual report for Brookhaven National Laboratory. Revision 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-12-31

Epidemiologic surveillance at DOE facilities consists of regular and systematic collection, analysis, and interpretation of data on absences due to illness and injury in the work force. Its purpose is to provide an early warning system for health problems occurring among employees at participating sites. Data are collected by coordinators at each site and submitted to the Epidemiologic Surveillance Data Center, located at the Oak Ridge Institute for Science and Education, where quality control procedures and analyses are carried out. Rates of absences and rates of diagnoses associated with absences are analyzed by occupation and other relevant variables. They maymore » be compared with the disease experience of different groups within the DOE work force and with populations that do not work for DOE to identify disease patterns or clusters that may be associated with work activities. This amended annual report corrects errors in the initial release of the BNL report for 1994. In this annual report, the 1994 morbidity data for BNL are summarized.« less

Elemental Composition of Mars Return Samples Using X-Ray Fluorescence Imaging at the National Synchrotron Light Source II

NASA Astrophysics Data System (ADS)

Thieme, J.; Hurowitz, J. A.; Schoonen, M. A.; Fogelqvist, E.; Gregerson, J.; Farley, K. A.; Sherman, S.; Hill, J.

2018-04-01

NSLS-II at BNL provides a unique and critical capability to perform assessments of the elemental composition and the chemical state of Mars returned samples using synchrotron radiation X-ray fluorescence imaging and X-ray absorption spectroscopy.

Atlas of Neutron Resonances

Science.gov Websites

Table Resonance Integrals & Thermal Cross Sections Book Review by J. Rowlands Nuclear Reaction Atlas of Neutron Resonances Preface: This book is the fifth edition of what was previously known as BNL extensive list of detailed individual resonance parameters for each nucleus, this book contains thermal

Research on Estrogen and Behavior Is a "Hot Topic" at the 2011 Society for Neuroscience Meeting

ScienceCinema

Biegon, Anat

2018-05-30

The Society for Neuroscience has selected recent research on estrogen and its effect on behavior conducted at BNL for its "hot topics" book distributed to reporters attending the society's 2011 meeting in Washington, D.C., November 12-16.

Research on Estrogen and Behavior Is a "Hot Topic" at the 2011 Society for Neuroscience Meeting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Biegon, Anat

The Society for Neuroscience has selected recent research on estrogen and its effect on behavior conducted at BNL for its "hot topics" book distributed to reporters attending the society's 2011 meeting in Washington, D.C., November 12-16.

First beam commissioning at BNL ERL SRF Gun

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, W.; Altinbas, Z.; Belomestnykh, S.

The 704 MHz SRF gun successfully generated the first photoemission beam in November of 2014. The configurations of the test and the sub-systems are described.The latest results of SRF commissioning, including the cavity performance, cathode QE measurements, beam current/energy measurements, are presented in the paper.

Ionic Liquids: Syrupy Solvents Promise New Efficient Ways to Generate, Store, and Use Energy

ScienceCinema

Wishart, James F.

2018-01-16

Many chemists want to speed things up — faster reactions can produce higher yields. But BNL chemist James Wishart would rather slow some reactions down. He studies syrupy materials known as ionic liquids, liquids composed entirely of positive and negative ions.

European Science Notes Information Bulletin Reports on Current European/ Middle Eastern Science

DTIC Science & Technology

1991-01-01

Pirelli SpaI Developmentof Passive Faes E Optc-ElectronlcSensorsfor Sistemas E Instrumentacion SA E Measurementsand Diagnostics In Univ. Politecnica...electronics, and microfabrication may In a companion presentation, H. Kirk, BNL, described have the same or larger impact on accelerators of the 21st the

CBETA Design Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoffstaetter, G.; Trbojevic, D.; Mayes, C.

This Design Report describes the baseline design of the Cornell-BNL ERL Test Accelerator, as it exists on the date of its publication in June 2017. The Design Report will not change frequently in the future. In contrast, the parameter sheets that summarize the CBETA design will respond as quickly and as thoroughly as necessary to maintain con guration control.

CBETA Design Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoffstaetter, G.; Trbojevic, D.; Mayes, C.

This Design Report describes the baseline design of the Cornell-BNL ERL Test Accelerator, as it exists on the date of its publication in June 2017. The Design Report will not change frequently in the future. In contrast, the parameter sheets that summarize the CBETA design will respond as quickly and as thoroughly as necessary to maintain configuration control.

BNL National Synchrotron Light Source activity report 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

During FY 1997 Brookhaven National Laboratory celebrated its 50th Anniversary and 50 years of outstanding achievement under the management of Associated Universities, Inc. This progress report is divided into the following sections: (1) introduction; (2) science highlights; (3) meetings and workshops; (4) operations; (5) projects; (6) organization; and (7) abstracts and publications.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cornacchia, Massimo

The VISA (Visible to Infrared SASE Amplifier) SASE free electron laser has been successfully operated at the Accelerator Test Facility (ATF) at BNL. High gain and saturation were observed at 840 nm. We describe here the diagnostic system, experimental procedures and data reduction algorithms, as the FEL performance was measured along the length of the undulator. We also discuss selected spectral radiation measurements.

90-50-10 Celebration: Ernest Courant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ernest Courant

BNL hosts a celebration titled “90-50-10” to celebrate the 90th birthday of Ernest Courant (of “strong focusing” fame), the 50th anniversary of the startup of the Alternating Gradient Synchrotron (AGS, home of three Nobel Prizes), and the 10th anniversary of first collisions at the Relativistic Heavy Ion Collider (RHIC).

405th Brookhaven Lecture

ScienceCinema

Vadim Ptitsyn

2018-04-18

"E-RHIC - Future Electron-Ion Collider at BNL. While RHIC scientists continue their quest to look deep into nuclear phenomena resulting from collisions of ion beams and beams of polarized protons, new design work is under way for a possible extension of RHIC to include e-RHIC, a 10-billion electron volt, high-intensity polarized proton beam.

Mechanical support and transport system used for the neutrino horn system at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walker, J.C.; Carroll, A.S.; Leonhardt, W.

1987-01-01

The study of neutrinos at the Alternating Gradient Synchrotron (AGS), Brookhaven National Laboratory (BNL), requires hardware for their initiation and control. The basics consist of a target, two horns and three collimators. This paper describes the installation, support and positioning of these components within a settling concrete blockhouse.

Power spectrum analyses of nuclear decay rates

NASA Astrophysics Data System (ADS)

Javorsek, D.; Sturrock, P. A.; Lasenby, R. N.; Lasenby, A. N.; Buncher, J. B.; Fischbach, E.; Gruenwald, J. T.; Hoft, A. W.; Horan, T. J.; Jenkins, J. H.; Kerford, J. L.; Lee, R. H.; Longman, A.; Mattes, J. J.; Morreale, B. L.; Morris, D. B.; Mudry, R. N.; Newport, J. R.; O'Keefe, D.; Petrelli, M. A.; Silver, M. A.; Stewart, C. A.; Terry, B.

2010-10-01

We provide the results from a spectral analysis of nuclear decay data displaying annually varying periodic fluctuations. The analyzed data were obtained from three distinct data sets: 32Si and 36Cl decays reported by an experiment performed at the Brookhaven National Laboratory (BNL), 56Mn decay reported by the Children's Nutrition Research Center (CNRC), but also performed at BNL, and 226Ra decay reported by an experiment performed at the Physikalisch-Technische Bundesanstalt (PTB) in Germany. All three data sets exhibit the same primary frequency mode consisting of an annual period. Additional spectral comparisons of the data to local ambient temperature, atmospheric pressure, relative humidity, Earth-Sun distance, and their reciprocals were performed. No common phases were found between the factors investigated and those exhibited by the nuclear decay data. This suggests that either a combination of factors was responsible, or that, if it was a single factor, its effects on the decay rate experiments are not a direct synchronous modulation. We conclude that the annual periodicity in these data sets is a real effect, but that further study involving additional carefully controlled experiments will be needed to establish its origin.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harker, Y.D.

On August 3-4, 1994, an INEL team made measurements related to a real-time monitoring system for use on the epithermal beam facility at the BMRR. BNL has installed two fission chambers in front of the beam collimator, which are to monitor the beam coming from the reactor. These two monitors are located with one just above the 16-cm dia. front aperture and the other is just below. The fission chambers contain depleted uranium, but because of the small amount of U-235 present, they respond to thermal and near thermal neutrons rather than fast neutrons. This feature combined with their relativelymore » small size (0.6 cm dia x 4 cm long) makes them very good monitors in the BMRR epithermal neutron beam. The INEL team worked with H.B. Lui (BNL) in performing initial tests of these monitors and established the settings to achieve stable operation. The main purpose of the measurement studies was to establish a basis for a monitoring method that tracks the dose the patient is receiving rather than the neutron fluence being delivered down the beam line.« less

COMMITTEES: SQM 2007 - International Conference On Strangeness In Quark Matter SQM 2007 - International Conference On Strangeness In Quark Matter

NASA Astrophysics Data System (ADS)

2008-04-01

Local Organising Committee Ivan Králik (IEP SAS, Košice) Vojtěch Petráček (Czechoslovakia Technical University, Prague) Ján Pišút (Comenius University, Bratislava) Emanuele Quercigh (CERN) Karel Šafařík (CERN), Co-chair Ladislav v Sándor (IEP SAS, Košice), Co-chair Boris Tomášik (Mateja Bela University, Banská Bystrica) Jozef Urbán (UPJŠ Košice) International Advisory Committee Jörg Aichelin, Nantes Federico Antinori, Padova Tamás Biró, Budapest Peter Braun-Munzinger, GSI Jean Cleymans, Cape Town László Csernai, Bergen Timothy Hallman, BNL Huan Zhong Huang, UCLA Sonja Kabana, Nantes Roy A Lacey, Stony Brook Carlos Lourenço, CERN Yu-Gang Ma, Shanghai Jes Masden, Aarhus Yasuo Miake, Tsukuba Berndt Müller, Duke Grazyna Odyniec, LBNL Helmut Oeschler, Darmstadt Jan Rafelski, Arizona Hans Georg Ritter, LBNL Jack Sandweiss, Yale George S F Stephans, MIT Horst Stöcker, Frankfurt Thomas Ullrich, BNL Orlando Villalobos-Baillie, Birmingham William A Zajc, Columbia

MeRHIC - staging approach to eRHIC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ptitsyn,V.; Beebe-Wang, J.; Ben-Zvi, I.

Design of a medium energy electron-ion collider (MeRHIC) is under development at the Collider-Accelerator Department at BNL. The design envisions construction of a 4 GeV electron accelerator in a local area inside and near the RHIC tunnel. Electrons will be produced by a polarized electron source and accelerated in energy recovery linacs. Collisions of the electron beam with 100 GeV/u heavy ions or with 250 GeV polarized protons will be arranged in the existing IP2 interaction region of RHIC. The luminosity of electron-proton collisions at the 10{sup 32} cm{sup -2}s{sup -1} level will be achieved with 50 mA CW electronmore » current and presently available proton beam parameters. Efficient proton beam cooling at collision energy may bring the luminosity to 10{sup 33} cm{sup -2}s{sup -1}. An important feature of MeRHIC is that it serves as a first stage of eRHIC, a future electron-ion collider at BNL with both higher luminosity and energy reach. The majority of MeRHIC accelerator components will be used in eRHIC.« less

Charged-particle pseudorapidity distributions in Au+Au collisions at sNN=62.4 GeV

NASA Astrophysics Data System (ADS)

Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; Nieuwenhuizen, G. J. Van; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Wenger, E.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wysłouch, B.

2006-08-01

The charged-particle pseudorapidity density for Au+Au collisions at sNN=62.4 GeV has been measured over a wide range of impact parameters and compared to results obtained at other energies. As a function of collision energy, the pseudorapidity distribution grows systematically both in height and width. The midrapidity density is found to grow approximately logarithmically between BNL Alternating Gradient Synchrotron (AGS) energies and the top BNL Relativistic Heavy Ion Collider (RHIC) energy. There is also an approximate factorization of the centrality and energy dependence of the midrapidity yields. The new results at sNN=62.4 GeV confirm the previously observed phenomenon of “extended longitudinal scaling” in the pseudorapidity distributions when viewed in the rest frame of one of the colliding nuclei. It is also found that the evolution of the shape of the distribution with centrality is energy independent, when viewed in this reference frame. As a function of centrality, the total charged particle multiplicity scales linearly with the number of participant pairs as it was observed at other energies.

Single event effects and laser simulation studies

NASA Technical Reports Server (NTRS)

Kim, Q.; Schwartz, H.; Mccarty, K.; Coss, J.; Barnes, C.

1993-01-01

The single event upset (SEU) linear energy transfer threshold (LETTH) of radiation hardened 64K Static Random Access Memories (SRAM's) was measured with a picosecond pulsed dye laser system. These results were compared with standard heavy ion accelerator (Brookhaven National Laboratory (BNL)) measurements of the same SRAM's. With heavy ions, the LETTH of the Honeywell HC6364 was 27 MeV-sq cm/mg at 125 C compared with a value of 24 MeV-sq cm/mg obtained with the laser. In the case of the second type of 64K SRAM, the IBM640lCRH no upsets were observed at 125 C with the highest LET ions used at BNL. In contrast, the pulsed dye laser tests indicated a value of 90 MeV-sq cm/mg at room temperature for the SEU-hardened IBM SRAM. No latchups or multiple SEU's were observed on any of the SRAM's even under worst case conditions. The results of this study suggest that the laser can be used as an inexpensive laboratory SEU prescreen tool in certain cases.

Teaming with Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, G.

BNL has started growing CdZnTeSe crystals for room-temperature radiation detector applications. The addition of Se to CdTe reduces the concentration of secondary phases and sub-grain boundary networks. The addition of Zn increases the energy band gap. Material characterization to understand the limiting factors of radiation detection material and to improve the properties continues to be a core element of an extensive R&D program at the LBNL’s ALS and BNL’s NSLS-II synchrotron facilities. ALS’s Beamline 3.3.2 is available for 60% of its beamtime and allows us to perform both White Beam X-ray Diffraction Topography and Micron Scale X-ray Detector Mapping. Themore » latter technique is extremely useful when measuring scintillators because it allows us to subtract contributions from the variability in the counting statistics, and also the fluctuations due to delta electrons, and non-proportionality. BNL has recently developed a new type of thermal neutron detector using pad technology in combination with 3He gas operated in ionization mode. The new detector is used for coded aperture thermal neutron imaging.« less

Proceedings of RIKEN BNL Research Center Workshop: The Approach to Equilibrium in Strongly Interacting Matter. Volume 118

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liao, J.; Venugopalan, R.; Berges, J.

The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory*. It is funded by the ''Rikagaku Kenkyusho'' (RIKEN, The Institute of Physical and Chemical Research) of Japan and the U. S. Department of Energy’s Office of Science. The RBRC is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has theory, lattice gauge computing and experimental components. It is presently exploring the possibility of an astrophysics component being added to the program. The purpose of this Workshopmore » is to critically review the recent progress on the theory and phenomenology of early time dynamics in relativistic heavy ion collisions from RHIC to LHC energies, to examine the various approaches on thermalization and existing issues, and to formulate new research efforts for the future. Topics slated to be covered include Experimental evidence for equilibration/isotropization, comparison of various approaches, dependence on the initial conditions and couplings, and turbulent cascades and Bose-Einstein condensation.« less

Correlation femtoscopy study at energies available at the JINR Nuclotron-based Ion Collider fAcility and the BNL Relativistic Heavy Ion Collider within a viscous hydrodynamic plus cascade model

NASA Astrophysics Data System (ADS)

Batyuk, P.; Karpenko, Iu.; Lednicky, R.; Malinina, L.; Mikhaylov, K.; Rogachevsky, O.; Wielanek, D.

2017-08-01

Correlation femtoscopy allows one to measure the space-time characteristics of particle production in relativistic heavy-ion collisions due to the effects of quantum statistics (QS) and final state interactions (FSIs). The main features of the femtoscopy measurements at top RHIC and LHC energies are considered as a manifestation of strong collective flow and are well interpreted within hydrodynamic models employing equation of state (EoS) with a crossover type transition between quark-gluon plasma (QGP) and hadron gas phases. The femtoscopy at lower energies was intensively studied at AGS and SPS accelerators and is being studied now in the Beam Energy Scan program (BES) at the BNL Relativistic Heavy Ion Collider in the context of exploration of the QCD phase diagram. In this article we present femtoscopic observables calculated for Au-Au collisions at √{sN N}=7.7 -62.4 GeV in a viscous hydro + cascade model vHLLE+UrQMD and their dependence on the EoS of thermalized matter.

BNL ATF II beamlines design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fedurin, M.; Jing, Y.; Stratakis, D.

The Brookhaven National Laboratory. Accelerator Test Facility (BNL ATF) is currently undergoing a major upgrade (ATF-II). Together with a new location and much improved facilities, the ATF will see an upgrade in its major capabilities: electron beam energy and quality and CO 2 laser power. The electron beam energy will be increased in stages, first to 100-150 MeV followed by a further increase to 500 MeV. Combined with the planned increase in CO 2 laser power (from 1-100 TW), the ATF-II will be a powerful tool for Advanced Accelerator research. A high-brightness electron beam, produced by a photocathode gun, willmore » be accelerated and optionally delivered to multiple beamlines. Besides the energy range (up to a possible 500 MeV in the final stage) the electron beam can be tailored to each experiment with options such as: small transverse beam size (<10 um), short bunch length (<100 fsec) and, combined short and small bunch options. This report gives a detailed overview of the ATFII capabilities and beamlines configuration.« less

Effect of respiratory syncytial virus on the growth of hepatocellular carcinoma cell-lines

PubMed Central

Choi, Song Hee; Park, Byoung Kwon; Lee, Keun-Wook; Chang, Jun; Lee, Younghee; Kwon, Hyung-Joo

2015-01-01

In several reports, the respiratory syncytial virus (RSV) was identified as an oncolytic virus in cancer cells (e.g., lung and prostate cancer). However, the effects of RSV in hepatocellular carcinoma (HCC) cells have not yet been investigated. Here, we observed the inhibitory effects of RSV infection in HCC cell-lines. Cell growth was significantly decreased by RSV infection in BNL-HCC, Hep3B, Huh-7 and SNU-739 cells. After RSV infection, plaque formation and syncytial formation were observed in affected Hep3B and Huh-7 cells. RSV protein-expression was also detected in Hep3B and Huh-7 cells; however, only Huh-7 cells showed apoptosis after RSV infection. Furthermore, inhibition of cell migration by RSV infection was observed in BNL-HCC, Hep3B, Huh-7 and SNU-739 cells. Therefore, further investigation is required to clarify the molecular mechanism of RSV-mediated inhibition of HCC cell growth, and to develop potential RSV oncolytic viro-therapeutics. [BMB Reports 2015; 48(10): 565-570] PMID:25739391

Multipacting in a grooved choke joint at SRF gun for BNL ERL prototype

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, W.; Ben-Zvi, I.; Belomestnykh, S.

2011-03-28

The 703 MHz superconducting gun for BNL ERL prototype was tested at JLab with and without choke-joint and cathode stalk. Without choke-joint and cathode stalk, the gradient reached was 25 MV/m with Q{sup 0} {approx} 6E9. The gun cathode insertion port is equipped with a grooved choke joint for multipacting suppression. We carried out tests with choke-joint and cathode stalk. The test results show that there are at least two barriers at about 3.5 MV/m and 5 MV/m. We considered several possibilities and finally found that fine details of the grooved shape are important for multipacting suppression. A triangular groovemore » with round crest may cause strong multipacting in the choke-joint at 3.5 MV/m, 5 MV/m and 10 MV/m. This paper presents the primary test results of the gun and discusses the multipacting analysis in the choke-joint. It also suggests possible solutions for the gun and multipacting suppressing for a similar structure.« less

Northeast Waste Management Enterprise (NEWME) 1996 annual/final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goland, A.; Kaplan, E.; Palmedo, P. Wortman, J.

1997-10-01

The Northeast Waste Management Enterprise was created in response to Dr. Clyde Frank`s vision of a new partnership between research, industrial, and financial sectors, with the goal of speeding development and use (particularly at U.S. Department of Energy [DOE] facilities) of environmental remediation technologies. It was anticipated that this partnership would also strengthen the international competitiveness of the U.S. environmental industry. Brookhaven National Laboratory`s (BNL) response to Dr. Frank was a proposal to create the Northeast Waste Management Alliance, later renamed the Northeast Waste Management Enterprise (NEWME). Recognizing the need to supplement its own technical expertise with acumen in business,more » financial management, and venture capital development, BNL joined forces with the Long Island Research Institute (LIRI). Since its inception at the end of FY 1993, NEWME has achieved several significant accomplishments in pursuing its original business and strategic plans. However, its successes have been constrained by a fundamental mismatch between the time scales required for technology commercialization, and the immediate need for available environmental technologies of those involved with ongoing environmental remediations at DOE facilities.« less

Assessment of mercury health risks to adults from coal combustion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lipfert, F.W.; Moskowitz, P.D.; Fthenakis, V.M.

1994-05-01

The U.S. Environmental Protection Agency (EPA) is preparing, for the U.S. Congress, a report evaluating the need to regulate mercury (Hg) emissions from electric utilities. This study, to be completed in 1995, will have important health and economic implications. In support of these efforts, the U.S. Department of Energy, Office of Fossil Energy, sponsored a risk assessment project at Brookhaven National Laboratory (BNL) to evaluate methylmercury (MeHg) hazards independently. In the BNL study, health risks to adults resulting from Hg emissions from a hypothetical 1000 MW{sub e} coal-fired power plant were estimated using probabilistic risk assessment techniques. The approach drawsmore » on the extant knowledge in each of the important steps in the calculation chain from emissions to health effects. Estimated results at key points in the chain were compared with actual measurements to help validate the modeled estimates. Two cases were considered: the baseline case (no local impacts), and the impact case (maximum local power-plant impact). The BNL study showed that the effects of emissions of a single power plant may double the background exposures to MeHg resulting from consuming fish obtained from a localized area near the power plant. Many implicit and explicit sources of uncertainty exist in this analysis. Those that appear to be most in need of improvement include data on doses and responses for potentially sensitive subpopulations (e.g., fetal exposures). Rather than considering hypothetical situations, it would also be preferable to assess the risks associated with actual coal-fired power plants and the nearby sensitive water bodies and susceptible subpopulations. Finally, annual total Hg emissions from coal burning and from other anthropogenic sources are still uncertain; this makes it difficult to estimate the effects of U.S. coal burning on global Hg concentration levels, especially over the long term.« less

CRADA No. BNL-C-97-10 between BNL and Cotton, Inc. Final abstract and final report [Final Report of Research carried out under DOE CRADA No. BNL-C-97-10 - "Prediction of Yield in Cotton"

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The objectives of this work were to determine if the numbér of fiber cell initials varied genetically and to compare the number of initials with that of mature fibers obtained at harvest time. The method used to count the number of fiber cell initials is direct, simple, quick and done while the plant is growing. In contrast, the currently used commercial process is indirect and needs large amount mature fibers gathered at harvest time. However, all current work on cotton yield is based on fiber numbers obtained by the indirect commercial process. Consequently, it was necessary to compare results obtainedmore » from the two methods using the same plants as the source of material. The results show that the number of fiber initials per ovule differed significantly (P>0.05) for seven cultivars in 1995 and 1996. AIso, a 1997 study shows the number of fiber initials varied by 15% over boll positions and environments, with rankings among cultivars generally consistent across boll positions and sampling times. Finally, although there were differences among cultivars for initial fiber cell number, all cultivars had nearly the same number of mature lint fibers per seed. This last finding is significant. It indicates that the rate of fiber cell initiation varies among cultivars; the lower the rate, the greater the difference between the number of initials and the number of mature fiber cells. If the rate of fiber initiation is relatively high, the number of initials and mature fibers differs by about 11%; if it is low, the difference is as high as 31%. Cotton breeders may be able to use genetic differences for the number of fiber initials and/or the rate of fiber cell initiation in crop improvement programs.« less

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

PubMed

Zuo, Yan; Gao, Jing; Yeung, William S B; Lee, Kai-Fai

2010-10-15

VAD1.3 (AEP1), a novel testis-specific gene, was first isolated from the testis of a retinol-treated vitamin-A-deficient (VAD) rat model. It is expressed at the acrosomal region of spermatids from postnatal day 25. VAD1.3 immunoreactivity is present in rat, human, monkey and porcine spermatids and spermatozoa, suggesting that VAD1.3 may play a role in acrosome formation. However, direct evidence on the detailed sub-cellular localization of the VAD1.3 protein in the acrosome and how VAD1.3 is involved in acrosome formation remains largely unknown. Here, we isolated and identified VAD1.3 interacting proteins by immunoprecipitation followed by mass spectrometry, and determined the functional motifs of VAD1.3 that were important for its specific sub-cellular location in vitro. We found that VAD1.3 bound to syntaxin 1 and β-actin proteins in vitro. Immunogold electron microscopic study localized VAD1.3 immunoreactivity to the acrosome membranes and matrix, and colocalized it with the β-actin protein. The full-length GFP-VAD (1-3601) and GFP-VAD (1-730) fusion proteins that contain the bipartite nucleus localization (BNL) signal were located in the peri-nucleus/Golgi of the transfected cells. In addition, the GFP signal colocalized with the endoplasmic reticulum marker and the syntaxin 1 protein in the transfected HeLa and GC-2spd cells. The C-terminal GFP-VAD (1770-3601) was expressed in the nucleus. Taken together, VAD1.3 interacts with β-actin and syntaxin 1 in vitro. The BNL signal may mediate the peri-nuclei localization of the protein that may interact with syntaxin 1 and β-actin for acrosome formation in spermatogenesis. Crown Copyright © 2010. Published by Elsevier Inc. All rights reserved.

Composite fatty acid ether amides suppress growth of liver cancer cells in vitro and in an in vivo allograft mouse model.

PubMed

Cao, Mengde; Prima, Victor; Nelson, David; Svetlov, Stanislav

2013-06-01

The heterogeneity of liver cancer, in particular hepatocellular carcinoma (HCC), portrays the requirement of multiple targets for both its treatment and prevention. Multifaceted agents, minimally or non-toxic for normal hepatocytes, are required to address the molecular diversity of HCC, including the resistance of putative liver cancer stem cells to chemotherapy. We designed and synthesized two fatty acid ethers of isopropylamino propanol, C16:0-AIP-1 and C18:1-AIP-2 (jointly named AIPs), and evaluated their anti-proliferative effects on the human HCC cell line Huh7 and the murine hepatoma cell line BNL 1MEA.7R.1, both in vitro and in an in vivo allograft mouse model. We found that AIP-1 and AIP-2 inhibited proliferation and caused cell death in both Huh7 and BNL 1MEA.7R.1 cells. Importantly, AIP-1 and AIP-2 were found to block the activation of putative liver cancer stem cells as manifested by suppression of clonal 'carcinosphere' development in growth factor-free and anchorage-free medium. The AIPs exhibited a relatively low toxicity against normal human or rat hepatocytes in primary cultures. In addition, we found that the AIPs utilized multifaceted pathways that mediate both autophagy and apoptosis in HCC, including the inhibition of AKTs and CAMK-1. In immune-competent mice, the AIPs significantly reduced BNL 1MEA.7R.1 cell-driven tumor allograft development, with a higher efficiency than sorafenib. A combination of AIP-1 + AIP-2 was most effective in reducing the tumor allograft incidence. AIPs represent a novel class of simple fatty acid derivatives that are effective against liver tumors via diverse pathways. They show a low toxicity towards normal hepatocytes. The addition of AIPs may represent a new avenue towards the management of chronic liver injury and, ultimately, the prevention and treatment of HCC.

Long baseline neutrino oscillation experiment at the AGS

NASA Astrophysics Data System (ADS)

Beavis, D.; Carroll, A.; Chiang, I.

1995-04-01

The authors present a design for a multidetector long baseline neutrino oscillation experiment at the BNL AGS. It has been approved by the BNL-HENP-PAC as AGS Experiment 889. The experiment will search for oscillations in the nu(sub mu) disappearance channel and the nu(sub mu) reversible reaction nu(sub e) appearance channel by means of four identical neutrino detectors located 1, 3, 24, and 68 km from the AGS neutrino source. Observed depletion of the nu(sub mu) flux (via quasi-elastic muon neutrino events, nu(sub mu)n yields mu(-)p) in the far detectors not attended by an observed proportional increase of the nu(sub e) flux (via quasi-elastic electron neutrino events, nu(sub e)n yields e(-)p) in those detectors will be prima facie evidence for the oscillation channel nu(sub mu) reversible reaction nu(sub tau). The experiment is directed toward exploration of the region of the neutrino oscillation parameters Delta m(exp 2) and sin(exp 2) 2 theta, suggested by the Kamiokande and IMB deep underground detectors but it will also explore a region more than two orders of magnitude larger than that of previous accelerator experiments. The experiment will run in a mode new to BNL. It will receive the fast extracted proton beam on the neutrino target approximately 20 hours per day when the AGS is not filling RHIC. A key aspect of the experimental design involves placing the detectors 1.5 degrees off the center line of the neutrino beam, which has the important advantage that the central value of the neutrino energy (approximately 1 GeV) and the beam spectral shape are, to a good approximation, the same in all four detectors. The proposed detectors are massive, imaging, water Cherenkov detectors similar in large part to the Kamiokande and IMB detectors. The design has profited from their decade-long experience, and from the detector designs of the forthcoming SNO and SuperKamiokande detectors.

Sedimentary sources of old high molecular weight dissolved organic carbon from the ocean margin benthic nepheloid layer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guo, L. Santschi, P.H.

2000-02-01

Average {sup 14}C ages of dissolved organic carbon (DOC) in the ocean are 3--6,000 years, and are influenced by old DOC from continental margins. However, sources of DOC from terrestrial, autochthonous, and sedimentary organic carbon seem to be too young to be responsible for the old DOC observed in the ocean. Since colloidal organic carbon (COC, i.e., high molecular weight DOC), which is chemically very similar to that of bulk DOC, can be effectively isolated from seawater using cross-flow ultrafiltration, it can hold clues to sources and pathways of DOC turnover in the ocean. Radiocarbon measurements on COC in themore » water column and benthic nepheloid layer (BNL) from two continental margin areas (the Middle Atlantic Bight and the Gulf of Mexico) and controlled laboratory experiments were carried out to study sources of old DOC in the ocean margin areas. Vertical distributions of suspended particulate matter (SPM), particulate organic carbon (POC), nitrogen (PON), and DOC in the water column and bottom waters near the sediment-water interface all demonstrate a well developed benthic nepheloid layer in both ocean margin areas. COC from the BNL was much older than COC from the overlying water column. These results, together with strong concentration gradients of SPM, POC, PON, and DOC, suggest a sedimentary source for organic carbon species and possibly for old COC as well in BNL waters. This is confirmed by the results from controlled laboratory experiments. The heterogeneity of {Delta}{sup 14}C signatures in bulk SOC thus points to a preferential release of old organic components from sediment resuspension, which can be the transport mechanism of the old benthic COC observed in ocean margin areas. Old COC from continental margin nepheloid layers may thus be a potential source of old DOC to the deep ocean.« less

Proceedings of RIKEN BNL Research Center Workshop: Brookhaven Summer Program on Nucleon Spin Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aschenauer, A.; Qiu, Jianwei; Vogelsang, W.

Understanding the structure of the nucleon is of fundamental importance in sub-atomic physics. Already the experimental studies on the electro-magnetic form factors in the 1950s showed that the nucleon has a nontrivial internal structure, and the deep inelastic scattering experiments in the 1970s revealed the partonic substructure of the nucleon. Modern research focuses in particular on the spin and the gluonic structure of the nucleon. Experiments using deep inelastic scattering or polarized p-p collisions are carried out in the US at the CEBAF and RHIC facilities, respectively, and there are other experimental facilities around the world. More than twenty yearsmore » ago, the European Muon Collaboration published their first experimental results on the proton spin structure as revealed in polarized deep inelastic lepton-nucleon scattering, and concluded that quarks contribute very little to the proton's spin. With additional experimental and theoretical investigations and progress in the following years, it is now established that, contrary to naive quark model expectations, quarks and anti-quarks carry only about 30% of the total spin of the proton. Twenty years later, the discovery from the polarized hadron collider at RHIC was equally surprising. For the phase space probed by existing RHIC experiments, gluons do not seem to contribute any to the proton's spin. To find out what carries the remaining part of proton's spin is a key focus in current hadronic physics and also a major driving force for the new generation of spin experiments at RHIC and Jefferson Lab and at a future Electron Ion Collider. It is therefore very important and timely to organize a series of annual spin physics meetings to summarize the status of proton spin physics, to focus the effort, and to layout the future perspectives. This summer program on 'Nucleon Spin Physics' held at Brookhaven National Laboratory (BNL) on July 14-27, 2010 [http://www.bnl.gov/spnsp/] is the second one following the Berkeley Summer Program taken place in June of 2009. This program at BNL focused on theory and had many presentations on a wide range of theoretical aspects on nucleon spin, from perturbative-QCD calculations to models, and to the first principle lattice calculation. It also had a good number of summary talks from all major experimental collaborations on spin physics. The program facilitated many discussions between theorists as well as experimentalists. With five transparencies from each presentation at the Summer Program, this proceedings provides a valuable summary on the status and progress, as well as the future prospects of spin physics.« less

More Than 200 Attend NREL/SNL/BNL Photovoltaic Reliability Workshops | News

Science.gov Websites

solar cells on the market today and by the lack of understanding of the causes of the changes. A document how modules respond to extended application of common stress tests. Observed changes in the see if these changes are also observed in the field. Presentations from the workshops are posted

DOE Office of Scientific and Technical Information (OSTI.GOV)

PAQUETTE,D.E.; BENNETT,D.B.; DORSCH,W.R.

THE DEPARTMENT OF ENERGY ORDER 5400.1, GENERAL ENVIRONMENTAL PROTECTION PROGRAM, REQUIRES THE DEVELOPMENT AND IMPLEMENTATION OF A GROUNDWATER PROTECTION PROGRAM. THE BNL GROUNDWATER PROTECTION MANAGEMENT PROGRAM DESCRIPTION PROVIDES AN OVERVIEW OF HOW THE LABORATORY ENSURES THAT PLANS FOR GROUNDWATER PROTECTION, MONITORING, AND RESTORATION ARE FULLY DEFINED, INTEGRATED, AND MANAGED IN A COST EFFECTIVE MANNER THAT IS CONSISTENT WITH FEDERAL, STATE, AND LOCAL REGULATIONS.

X-ray microtomography of porous media at BNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dowd, B.

This session is comprised of pertinent information about the historical aspects, current status of research, technical achievements, and future plans in X-ray computed microtomography at Brookhaven National Laboratories. An explanation with specifications and diagrams of X-ray instrumentation is provided. Several high resolution 3-D color images of reservoir rock drill cores and other materials are included.

From strangeness enhancement to quark-gluon plasma discovery

NASA Astrophysics Data System (ADS)

Koch, Peter; Müller, Berndt; Rafelski, Johann

2017-11-01

This is a short survey of signatures and characteristics of the quark-gluon plasma in the light of experimental results that have been obtained over the past three decades. In particular, we present an in-depth discussion of the strangeness observable, including a chronology of the experimental effort to detect QGP at CERN-SPS, BNL-RHIC, and CERN-LHC.

429th Brookhaven Lecture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert P. Crease

2007-10-31

Robert P. Crease, historian for Brookhaven National Laboratory and Chair of the Philosophy Department at Stony Brook University, presents "How Big Science Came to Long Island: The Birth of Brookhaven Lab," covering the founding of the Laboratory, the key figures involved in starting BNL, and the many problems that had to be overcome in creating and designing its first big machines.

429th Brookhaven Lecture

ScienceCinema

Robert P. Crease

2017-12-09

Robert P. Crease, historian for Brookhaven National Laboratory and Chair of the Philosophy Department at Stony Brook University, presents "How Big Science Came to Long Island: The Birth of Brookhaven Lab," covering the founding of the Laboratory, the key figures involved in starting BNL, and the many problems that had to be overcome in creating and designing its first big machines.

Proceedings of the first international symposium on neutron capture therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fairchild, R.G.; Brownell, G.L.

This meeting was arranged jointly by MIT and BNL in order to illuminate progress in the synthesis and targeting of boron compounds and to evaluate and document progress in radiobiological and dosimetric aspects of neutron capture therapy. It is hoped that this meeting will facilitate transfer of information between groups working in these fields, and encourage synergistic collaboration.

Effects of Changes to Arc Dipole Length

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tepikian, Steven

1994-06-01

The arc dipole magnetic length in the design is 9.45m. The first arc magnets were made with BNL parts and have the proper length, however, the dipoles made with Grumman parts has a shorter magnetic length. The current projected magnet length of the Grumman dipoles is 9.422m. In this note we discuss the consequences of this change.

International Conference on Human Resource Development for Nuclear Power Programmes: Strategies for Education and Training, Networking and Knowledge Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pepper, Susan E.; Bachner, Katherine M.

The report includes a summary of the overall workshop results and also copies of the two papers and interactive presentations given by BNL staff at the meeting. The two presentations were titled ''The value of the Junior Professional Officer (JPO) program to the IAEA and its Member States'' and ''Promoting intercultural competencies''.

Near-Bottom Turbulence and Sediment Resuspension Induced by Nonlinear Internal Waves

DTIC Science & Technology

2011-09-30

boundary layer (BBL) turbulence and particulate resuspension leading to benthic nepheloid layer ( BNL ) formation. OBJECTIVES The specific...identify mechanisms for the capturing of nearbed particles by the BBL-turbulence and their transport/deposition into BNLs . • Analyze field...resuspended particle distributions under NLIWs, a reliable proxy of BNLs , can be used to quantify the transmission or backscatter of optical/acoustic

Pest Resistance and agronomic performance of advanced BARBREN lines compared to commercial cultivars and the germplasm line BARBREN 713

USDA-ARS?s Scientific Manuscript database

The germplasm line BARBREN 713, which has resistance to both root-knot and reniform nematodes was released in 2012. Its major resistance to reniform nematodes is due to the Ren2 gene derived from Gossypium barbadense GB 713 and located near the DNA marker BNL 3279_105 on chromosome 21. Other lines...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barber, Laura Jeaneen

The purpose of the L’Innovator is to assemble unique, state-of-the-art IP bundles developed at the national labs that aggregate synergistic technologies in furtherance of the emerging hydrogen and fuel cell market. The first L’Innovator IP bundle consists of Oxygen Reduction Reaction (ORR) Catalyst technology developed at Brookhaven National Laboratory (BNL), combined with Membrane Electrode Assembly (MEA) technology developed at Los Alamos National Laboratory (LANL).

TVDG Contacts

Science.gov Websites

for Sandy Fax By Fax: 1 631 344 4583 Attention Chuck Carlson EMail By E-Mail: Send E-Mail to Chuck Group Leader James Alessi Telephone: 1-631-344-4004 E-Mail: Peter Thieberger Information can be returned 1 631 344 4581. An organizational list of staff members and how to contact them. The BNL E-Mail and

A microdosimetric study of {sup 10}B(n,{alpha}){sup 7}Li and {sup 157}Gd(n,{gamma}) reactions for neutron capture therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, C.K.C.; Sutton, M.; Evans, T.M.

1999-01-01

This paper presents the microdosimetric analysis for the most interesting cell survival experiment recently performed at the Brookhaven National Laboratory (BNL). In this experiment, the cells were first treated with a gadolinium (Gd) labeled tumor-seeking boronated porphyrin (Gd-BOPP) or with BOPP alone, and then irradiated with thermal neutrons. The resulting cell-survival curves indicate that the {sup 157}Gd(n,{gamma}) reactions are very effective in cell killing. The death of a cell treated with Gd-BOPP was attributed to either the {sup 10}B(n,{alpha}){sup 7}Li reactions or the {sup 157}Gd(n,{gamma}) reactions (or both). However, the quantitative relationship between the two types of reaction and themore » cell-survival fraction was not clear. This paper presents the microdosimetric analysis for the BNL experiment based on the measured experimental parameters, and the results clearly suggest a quantitative relationship between the two types of reaction and the cell survival fraction. The results also suggest new research in gadolinium neutron capture therapy (GdNCT) which may lead to a more practical modality than the boron neutron capture therapy (BNCT) for treating cancers.« less

Faculty and Student Teams and National Laboratories: Expanding the Reach of Research Opportunities and Workforce Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blackburn,N.; White, K.; Stegman, M.

The Faculty and Student Teams (FaST) Program, a cooperative effort between the US Department of Energy (DOE) Office of Science and the National Science Foundation (NSF), brings together collaborative research teams composed of a researcher at Brookhaven National Laboratory, and a faculty member with two or three undergraduate students from a college or university. Begun by the Department of Energy in 2000 with the primary goal of building research capacity at a faculty member's home institution, the FaST Program focuses its recruiting efforts on faculty from colleges and universities with limited research facilities and those institutions that serve populations under-representedmore » in the fields of science, engineering and technology, particularly women and minorities. Once assembled, a FaST team spends a summer engaged in hands-on research working alongside a laboratory scientist. This intensely collaborative environment fosters sustainable relationships between the faulty members and BNL that allow faculty members and their BNL colleagues to submit joint proposals to federal agencies, publish papers in peer-reviewed journals, reform local curriculum, and develop new or expand existing research labs at their home institutions.« less

Study of correlations from Ab-Initio Simulations of Liquid Water

NASA Astrophysics Data System (ADS)

Soto, Adrian; Fernandez-Serra, Marivi; Lu, Deyu; Yoo, Shinjae

An accurate understanding of the dynamics and the structure of H2O molecules in the liquid phase is of extreme importance both from a fundamental and from a practical standpoint. Despite the successes of Molecular Dynamics (MD) with Density Functional Theory (DFT), liquid water remains an extremely difficult material to simulate accurately and efficiently because of fine balance between the covalent O-H bond, the hydrogen bond and the attractive the van der Waals forces. Small errors in those produce dramatic changes in the macroscopic properties of the liquid or in its structural properties. Different density functionals produce answers that differ by as much as 35% in ambient conditions, with none producing quantitative results in agreement with experiment at different mass densities. In order to understand these differences we perform an exhaustive scanning of the geometrical coordinates of MD simulations and study their statistical correlations with the simulation output quantities using advanced correlation analyses and machine learning techniques. This work was partially supported by DOE Award No. DE-FG02-09ER16052, by DOE Early Career Award No. DE-SC0003871, by BNL LDRD 16-039 project and BNL Contract No. DE-SC0012704.

Study of correlations from Ab-Initio Simulations of Liquid Water

NASA Astrophysics Data System (ADS)

Soto, Adrian; Fernandez-Serra, Marivi; Lu, Deyu; Yoo, Shinjae

An accurate understanding of the dynamics and the structure of H2O molecules in the liquid phase is of extreme importance both from a fundamental and from a practical standpoint. Despite the successes of Molecular Dynamics (MD) with Density Functional Theory (DFT), liquid water remains an extremely difficult material to simulate accurately and efficiently because of fine balance between the covalent O-H bond, the hydrogen bond and the attractive the van der Waals forces. Small errors in those produce dramatic changes in the macroscopic properties of the liquid or in its structural properties. Different density functionals produce answers that differ by as much as 35% in ambient conditions, with none producing quantitative results in agreement with experiment at different mass densities [J. Chem Phys. 139, 194502(2013)]. In order to understand these differences we perform an exhaustive scanning of the geometrical coordinates of MD simulations and study their statistical correlations with the simulation output quantities using advanced correlation analyses and machine learning techniques. This work was partially supported by DOE Award No. DE-FG02-09ER16052, by DOE Early Career Award No. DE-SC0003871, by BNL LDRD 16-039 project and BNL Contract No. DE-SC0012704.

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM. ANNUAL REPORT TO THE DEPARTMENT OF ENERGY, DECEMBER 1998.

DOE Office of Scientific and Technical Information (OSTI.GOV)

OGEKA,G.J.

1998-12-31

In FY 1998, the BNL LDBD Program funded 20 projects, 4 of which were new starts, at a total cost of $2,563,681. The small number of new starts was a consequence of severe financial problems that developed between FY 1997 and 1998. Emphasis was given to complete funding for approved multi-year proposals. Following is a table which lists all of the FY 1998 funded projects and gives a history of funding for each by year. Several of these projects have already experienced varying degrees of success as indicated in the individual Project Program Summaries which follow. A total of 17more » informal publications (abstracts, presentations, BNL reports and workshop papers) were reported and an additional 13 formal (full length) papers were either published, are in press or being prepared for publication. The investigators on five projects have filed for a patent. Seven of the projects reported that proposals/grants had either been funded or were submitted for funding. In conclusion, a significant measure of success is already attributable to the FY 1998 LDBD Program in the short period of time involved. The Laboratory has experienced a significant scientific gain by these achievements.« less

The DARPA compact superconducting x-ray lithography source features. [Defense Advanced Research Projects Agency (DARPA)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heese, R.; Kalsi, S.; Leung, E.

1991-01-01

Under DARPA sponsorship, a compact Superconducting X-ray Lithography Source (SXLS) is being designed and built by the Brookhaven National Laboratory (BNL) with industry participation from Grumman Corporation and General Dynamics. This source is optimized for lithography work for sub-micron high density computer chips, and is about the size of a billiard table (1.5 m {times} 4.0 m). The machine has a racetrack configuration with two 180{degree} bending magnets being designed and built by General Dynamics under a subcontract with Grumman Corporation. The machine will have 18 photon ports which would deliver light peaked at a wave length of 10 Angstroms.more » Grumman is commercializing the SXLS device and plans to book orders for delivery of industrialized SXLS (ISXLS) versions in 1995. This paper will describe the major features of this device. The commercial machine will be equipped with a fully automated user-friendly control systems, major features of which are already working on a compact warm dipole ring at BNL. This ring has normal dipole magnets with dimensions identical to the SXLS device, and has been successfully commissioned. 4 figs., 1 tab.« less

COMMITTEES: SQM2009 - 14th International Conference on Strangeness in Quark Matter SQM2009 - 14th International Conference on Strangeness in Quark Matter

NASA Astrophysics Data System (ADS)

2008-04-01

Local Organizing Committee Takeshi Kodama Chair, UFRJ Jun Takahashi Co-chair, UNICAMP Ignácio Bediaga e Hickman CBPF Eduardo Fraga UFRJ Frederique Grassi USP Yogiro Hama USP Gastão Krein IFT Erasmo Madureira Ferreira UFRJ Marcelo G. Munhoz USP Fernando Navarra USP Sandra Padula IFT Alejandro Szanto de Toledo USP César Augusto Zen Vasconcellos UFRGS International Advisory Committee Jörg Aichelin Nantes Federico Antinori Padova Tamás Biró Budapest Peter Braun-Munzinger GSI Jean Cleymans Cape Town Láaszló Csernai Bergen Timothy Hallman BNL Huan Zhong Huang UCLA Takeshi Kodama Rio de Janeiro Yu-Gang Ma Shanghai Jes Madsen Aarhus Ágnes Mócsy Pratt University Berndt Müller Duke University Grazyna Odyniec LBNL Helmut Oeschler Darmstadt Johann Rafelski Arizona Hans Georg Ritter LBNL Gunther Rolland MIT Karel Šafařík CERN Ladislav Sandor Kosice University Jack Sandweiss Yale University George S F Stephans MIT Horst Stöcker Frankfurt Larry McLerranBNL Helmut Satz Universitä Bielefeld Nu Xu LBNL Fuqiang Wang Purdue University William A. Zajc Columbia University Pengfei Zhuang Tsinghua University

Thermo Scientific Sulfur Dioxide Analyzer Instrument Handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springston, S. R.

The Sulfur Dioxide Analyzer measures sulfur dioxide based on absorbance of UV light at one wavelength by SO2 molecules which then decay to a lower energy state by emitting UV light at a longer wavelength. Specifically, SO2 + hυ1 →SO2 *→SO2 + hυ2 The emitted light is proportional to the concentration of SO2 in the optical cell. External communication with the analyzer is available through an Ethernet port configured through the instrument network of the AOS systems. The Model 43i-TLE is part of the i-series of Thermo Scientific instruments. The i-series instruments are designed to interface with external computers throughmore » the proprietary Thermo Scientific iPort Software. However, this software is somewhat cumbersome and inflexible. BNL has written an interface program in National Instruments LabView that both controls the Model 43i-TLE Analyzer AND queries the unit for all measurement and housekeeping data. The LabView vi (the software program written by BNL) ingests all raw data from the instrument and outputs raw data files in a uniform data format similar to other instruments in the AOS and described more fully in Section 6.0 below.« less

Fucoxanthin enhances HO-1 and NQO1 expression in murine hepatic BNL CL.2 cells through activation of the Nrf2/ARE system partially by its pro-oxidant activity.

PubMed

Liu, Cheng-Ling; Chiu, Yu-Ting; Hu, Miao-Lin

2011-10-26

To determine whether fucoxanthin, a major carotenoid in brown sea algae, may activate cellular antioxidant enzymes via up-regulation of the Nrf2/antioxidant-response element (ARE) pathway, we incubated mouse hepatic BNL CL.2 cells with fucoxanthin (0.5-20 μM) for 0-24 h. We found that fucoxanthin (≥5 μM) significantly increased cellular reactive oxygen species (ROS) at 6 h of incubation, whereas preincubation with α-d-tocopherol (30 μM) significantly attenuated the increase of ROS, indicating the pro-oxidant nature of fucoxanthin. Fucoxanthin significantly increased the phosphorylation of ERK and p38 and markedly increased nuclear Nrf2 protein accumulation after incubation for 12 h. Moreover, fucoxanthin significantly enhanced binding activities of nuclear Nrf2 with ARE and increased mRNA and protein expression of HO-1 and NQO1 after incubation for 12 h. siRNA inhibition of Nrf2 led to markedly decreased HO-1 and NQO1 protein expression. Thus, fucoxanthin may exert its antioxidant activity, at least partly, through its pro-oxidant actions.

Lambda phage-based vaccine induces antitumor immunity in hepatocellular carcinoma.

PubMed

Iwagami, Yoshifumi; Casulli, Sarah; Nagaoka, Katsuya; Kim, Miran; Carlson, Rolf I; Ogawa, Kosuke; Lebowitz, Michael S; Fuller, Steve; Biswas, Biswajit; Stewart, Solomon; Dong, Xiaoqun; Ghanbari, Hossein; Wands, Jack R

2017-09-01

Hepatocellular carcinoma (HCC) is a difficult to treat tumor with a poor prognosis. Aspartate β-hydroxylase (ASPH) is a highly conserved enzyme overexpressed on the cell surface of both murine and human HCC cells. We evaluated therapeutic effects of nanoparticle lambda (λ) phage vaccine constructs against ASPH expressing murine liver tumors. Mice were immunized before and after subcutaneous implantation of a syngeneic BNL HCC cell line. Antitumor actively was assessed by generation of antigen specific cellular immune responses and the identification of tumor infiltrating lymphocytes. Prophylactic and therapeutic immunization significantly delayed HCC growth and progression. ASPH-antigen specific CD4+ and CD8+ lymphocytes were identified in the spleen of tumor bearing mice and cytotoxicity was directed against ASPH expressing BNL HCC cells. Furthermore, vaccination generated antigen specific Th1 and Th2 cytokine secretion by immune cells. There was widespread necrosis with infiltration of CD3+ and CD8+ T cells in HCC tumors of λ phage vaccinated mice compared to controls. Moreover, further confirmation of anti-tumor effects on ASPH expressing tumor cell growth were obtained in another murine syngeneic vaccine model with pulmonary metastases. These observations suggest that ASPH may serve as a highly antigenic target for immunotherapy.

Microdosimetric intercomparison of BNCT beams at BNL and MIT.

PubMed

Burmeister, Jay; Riley, Kent; Coderre, Jeffrey A; Harling, Otto K; Ma, Ruimei; Wielopolski, Lucian; Kota, Chandrasekhar; Maughan, Richard L

2003-08-01

Microdosimetric measurements have been performed at the clinical beam intensities in two epithermal neutron beams, the Brookhaven Medical Research Reactor and the M67 beam at the Massachusetts Institute of Technology Research Reactor, which have been used to treat patients with Boron Neutron Capture Therapy (BNCT). These measurements offer an independent assessment of the dosimetry used at these two facilities, as well as provide information about the radiation quality not obtainable from conventional macrodosimetric techniques. Moreover, they provide a direct measurement of the absorbed dose resulting from the BNC reaction. BNC absorbed doses measured within this study are approximately 15% lower than those estimated using foil activation at both MIT and BNL. Finally, an intercomparison of the characteristics and radiation quality of these two clinical beams is presented. The techniques described here allow an accurate quantitative comparison of the physical absorbed dose as well as a measure of the biological effectiveness of the absorbed dose delivered by different epithermal beams. No statistically significant differences were observed in the predicted RBEs of these two beams. The methodology presented here can help to facilitate the effective sharing of clinical results in an effort to demonstrate the clinical utility of BNCT.

Synergistic effects of N-ethyl-N-nitrosourea (an alkylating agent with a low Swain-Scott substrate constant) and X-rays in the stamen hairs of Tradescantia clone BNL 4430.

PubMed

Shima, N; Ichikawa, S

1997-01-01

The mutagenic interaction between N-ethyl-N-nitrosourea (ENU) and X-rays was tested in the stamen hairs of Tradescantia clone BNL 4430, a blue/pink heterozygote. ENU, a monofunctional alkylating agent with a low Swain-Scott substrate constant (s) of 0.26, exhibited a strong cytotoxicity. ENU-induced somatic pink mutation frequency per 10(4) hair-cell divisions increased with increasing ENU dose, with a slope of 1.243 on a log-log graph, the slope value being similar to that for X-ray-induced mutation frequency. Three out of five combined treatments with ENU and X-rays produced mutation frequencies significantly higher than those expected from the additive effects of the two mutagens. Clear synergistic effects were detected when relatively higher X-ray doses were applied, resembling those confirmed earlier between methyl methanesulfonate (MMS) and X-rays, although the s value for ENU is very much smaller than that (0.88) for MMS. It is therefore concluded that mutagenic interactions between alkylating agents and X-rays do not have any clear relationship with the s values.

Correlation functions of net-proton multiplicity distributions in Au + Au collisions at energies available at the BNL Relativistic Heavy Ion Collider from a multiphase transport model

NASA Astrophysics Data System (ADS)

Lin, Yufu; Chen, Lizhu; Li, Zhiming

2017-10-01

Fluctuations of conserved quantities are believed to be sensitive observables to probe the signature of the QCD phase transition and critical point. It was argued recently that measuring the genuine correlation functions (CFs) could provide cleaner information on possible nontrivial dynamics in heavy-ion collisions. With the AMPT (a multiphase transport) model, the centrality and energy dependence of various orders of CFs of net protons in Au + Au collisions at √{sN N}=7.7 , 11.5, 19.6, 27, 39, 62.4, and 200 GeV are investigated. The model results show that the number of antiprotons is important and should be taken into account in the calculation of CFs at high energy and/or in peripheral collisions. It is also found that the contribution of antiprotons is more important for higher order correlations than for lower ones. The CFs of antiprotons and mixed correlations play roles comparable to those of protons at high energies. Finally, we make comparisons between the model calculation and experimental data measured in the STAR experiment at the BNL Relativistic Heavy Ion Collider.

Acoustical evaluation of preschool classrooms

NASA Astrophysics Data System (ADS)

Yang, Wonyoung; Hodgson, Murray

2003-10-01

An investigation was made of the acoustical environments in the Berwick Preschool, Vancouver, in response to complaints by the teachers. Reverberation times (RT), background noise levels (BNL), and in-class sound levels (Leq) were measured for acoustical evaluation in the classrooms. With respect to the measured RT and BNL, none of the classrooms in the preschool were acceptable according to the criteria relevant to this study. A questionnaire was administered to the teachers to assess their subjective responses to the acoustical and nonacoustical environments of the classrooms. Teachers agreed that the nonacoustical environments in the classrooms were fair, but that the acoustical environments had problems. Eight different classroom configurations were simulated to improve the acoustical environments, using the CATT room acoustical simulation program. When the surface absorption was increased, both the RT and speech levels decreased. RASTI was dependent on the volumes of the classrooms when the background noise levels were high; however, it depended on the total absorption of the classrooms when the background noise levels were low. Ceiling heights are critical as well. It is recommended that decreasing the volume of the classrooms is effective. Sound absorptive materials should be added to the walls or ceiling.

Radical Scavenging Activities of Tannin Extracted from Amaranth (Amaranthus caudatus L.).

PubMed

Jo, Hyeon-Ju; Chung, Kang-Hyun; Yoon, Jin A; Lee, Kwon-Jai; Song, Byeong Chun; An, Jeung Hee

2015-06-01

This study investigates the bioactivity of tannin from amaranth (Amaranthus caudatus L.) extracts. The antioxidant activities of the extracts from amaranth leaves, flowers, and seeds were evaluated. Tannin from leaves of amaranth has been evaluated for superoxide scavenging activity by using DPPH and ABTS(+) analysis, reducing power, protective effect against H2O2-induced oxidative damage in L-132 and BNL-CL2 cells, and inhibition of superoxide radical effects on HL-60 cells. At a concentration of 100 μg/ml, tannin showed protective effects and restored cell survival to 69.2% and 41.8% for L-132 and BNL-CL2 cells, respectively. Furthermore, at the same concentration, tannin inhibited 41% of the activity of the superoxide radical on HL-60 cells and 43.4% of the increase in nitric oxide levels in RAW 264.7 cells. The expression levels of the antioxidant-associated protein SOD-1 were significantly increased in a concentration-dependent manner in RAW 264.7 cells treated with tannin from amaranth leaves. These results suggest that tannin from the leaves of Amaranthus caudatus L. is a promising source of antioxidant component that can be used as a food preservative or nutraceutical.

LIBMAKER

DOE Office of Scientific and Technical Information (OSTI.GOV)

2015-08-01

Version 00 COG LibMaker contains various utilities to convert common data formats into a format usable by the COG - Multi-particle Monte Carlo Code System package, (C00777MNYCP01). Utilities included: ACEtoCOG - ACE formatted neutron data: Currently ENDFB7R0.BNL, ENDFB7R1.BNL, JEFF3.1, JEFF3.1.1, JEFF3.1.2, MCNP.50c, MCNP.51c, MCNP.55c, MCNP.66c, and MCNP.70c. ACEUtoCOG - ACEU formatted photonuclear data: Currently PN.MCNP.30c and PN.MCNP.70u. ACTLtoCOG - Creates a COG library from ENDL formatted activation data COG library. EDDLtoCOG - Creates a COG library from ENDL formatted LLNL deuteron data. ENDLtoCOG - Creates a COG library from ENDL formatted LLNL neutron data. EPDLtoCOG - Creates a COG librarymore » from ENDL formatted LLNL photon data. LEX - Creates a COG dictionary file. SAB.ACEtoCOG - Creates a COG library from ACE formatted S(a,b) data. SABtoCOG - Creates a COG library from ENDF6 formatted S(a,b) data. URRtoCOG - Creates a COG library from ACE formatted probability table data. This package also includes library checking and bit swapping capability.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Litvinenko,V.; Yakimenko, V.

We propose undertaking a demonstration experiment on suppressing spontaneous undulator radiation from an electron beam at BNL's Accelerator Test Facility (ATF). We describe the method, the proposed layout, and a possible schedule. There are several advantages in strongly suppressing shot noise in the electron beam, and the corresponding spontaneous radiation. The self-amplified spontaneous (SASE) emission originating from shot noise in the electron beam is the main source of noise in high-gain FEL amplifiers. It may negatively affect several HG FEL applications ranging from single- to multi-stage HGHG FELs. SASE saturation also imposes a fundamental hard limit on the gain ofmore » an FEL amplifier in a coherent electron-cooling scheme. A novel active method for suppressing shot noise in relativistic electron beams by many orders-of-magnitude was recently proposed. While theoretically such strong suppression appears feasible, the performance and applicability of this novel method must be evaluated experimentally. Several practical questions about the proposed noise suppressor, such as 3D effects and/or sensitivity to the e-beam parameters also require experimental clarification. To do this, we propose here a proof-of-principle experiment using elements of the VISA FEL at BNL's Accelerator Test Facility.« less

Large Scale Accelerator Production of 225Ac: Effective Cross sections for 78-192 MeV Protons Incident on 232Th Targets

DOE PAGES

Griswold, Justin R; Medvedev, Dmitri G.; Engle, Jonathan W.; ...

2016-09-28

Actinium-225 and 213Bi have been used successfully in targeted alpha therapy (TAT) in preclinical and clinical research. This paper is a continuation of research activities aiming to expand the availability of 225Ac. The high energy proton spallation reaction on natural thorium metal target has been utilized to produce millicurie quantities of 225Ac. The results of sixteen irradiation experiments of Th metal at beam energies between 78 and 200 MeV are summarized in this work. Irradiations have been conducted at Brookhaven National Laboratory (BNL) and Los Alamos National Laboratory (LANL), while target dissolution and processing was carried out at Oak Ridgemore » National Laboratory (ORNL). Excitation functions for actinium and thorium isotopes as well as for some of the fission products are presented. The cross sections for production of 225Ac range from 3.6 to 16.7 mb in the incident proton energy range of 78 to 192 MeV. Based on these data, production of Curie quantities of 225Ac is possible by irradiating a 5.0 g cm -2232Th target for 10 days in either BNL or LANL proton irradiation facilities.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springston, Stephen R.

The Sulfur Dioxide Analyzer measures sulfur dioxide based on absorbance of UV light at one wavelength by SO 2 molecules which then decay to a lower energy state by emitting UV light at a longer wavelength. Specifically, SO 2 + hυ1 →SO 2 *→SO 2 + hυ2 The emitted light is proportional to the concentration of SO 2 in the optical cell. External communication with the analyzer is available through an Ethernet port configured through the instrument network of the AOS systems. The Model 43i-TLE is part of the i-series of Thermo Scientific instruments. The i-series instruments are designed tomore » interface with external computers through the proprietary Thermo Scientific iPort Software. However, this software is somewhat cumbersome and inflexible. Brookhaven National Laboratory (BNL) has written an interface program in National Instruments LabView that both controls the Model 43i-TLE Analyzer AND queries the unit for all measurement and housekeeping data. The LabView vi (the software program written by BNL) ingests all raw data from the instrument and outputs raw data files in a uniform data format similar to other instruments in the AOS and described more fully in Section 6.0 below.« less

Strange Particles and Heavy Ion Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bassalleck, Bernd; Fields, Douglas

This very long-running grant has supported many experiments in nuclear and particle physics by a group from the University of New Mexico. The gamut of these experiments runs from many aspects of Strangeness Nuclear Physics, to rare Kaon decays, to searches for exotic Hadrons such as Pentaquark or H-Dibaryon, and finally to Spin Physics within the PHENIX collaboration at RHIC. These experiments were performed at a number of laboratories worldwide: first and foremost at Brookhaven National Lab (BNL), but also at CERN, KEK, and most recently at J-PARC. In this Final Technical Report we summarize progress and achievements for thismore » award since our last Progress Report, i.e. for the period of fall 2013 until the award’s termination on November 30, 2015. The report consists of two parts, representing our two most recent experimental efforts, participation in the Nucleon Spin Physics program of the PHENIX experiment at RHIC, the Relativistic Heavy Ion Collider at BNL – Task 1, led by Douglas Fields; and participation in several Strangeness Nuclear Physics experiments at J-PARC, the Japan Proton Accelerator Research Center in Tokai-mura, Japan – Task 2, led by Bernd Bassalleck.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vaswani, A.N.; Howard, J.E.

This is the 17th and final report of the Marshall Islands Medical Program as carried out by the Brookhaven National Laboratory (BNL). The purpose of these publications has been to provide information on the medical status of 253 Marshallese exposed to radiation fallout in 1954. The medical program fulfills a commitment to disclose unique medical information relevant to public health. Details of the Bravo thermonuclear accident that caused the exposure have been published. A 1955 article in the Journal of the American Medical Association, which described the acute medical effects on the population that required special medical care, remains amore » definitive and relevant description of events. Marshallese participation in this Congressionally mandated program is voluntary. Throughout the 44 years of the program, each participating individual`s relevant medical findings, laboratory data, disease morbidity, and mortality have been published in the BNL reports in a manner preserving patient confidentiality. In each report, there has been an attempt to interpret these findings and to infer the role of radiation exposure in their development. An equally important aspect of the reports has been the presentation of data that allows for analyses of the medical consequences of the Marshallese exposure.« less

Strain-dependent release of cytokines modulated by Lactobacillus salivarius human isolates in an in vitro model

PubMed Central

2010-01-01

Background Oral administration of probiotics is known to modulate cytokines profile not only locally, but also systemically. Four strains of Lactobacillus salivarius, LDR0723, BNL1059, RGS1746 and CRL1528, were evaluated for their ability to modulate release of pro- and anti-inflammatory cytokines. Findings Strains were assessed for effects on production of Interleukin-12 (IL-12), Interferon-γ (IFN-γ), Interleukin-4 (IL-4) and Interleukin-5 (IL-5) by incubating bacterial suspensions with THP-1 macrophage like cells. Cytokines were determined by means of specific quantitative enzyme-linked immunosorbent assays. LDR0723 and CRL1528 led to a sustained increment in production of IL-12 and IFN-γ and to a decrease in release of IL-4 and IL-5, while BNL1059 and RGS1746 favoured Th2 response, leading to a decrease in Th1/Th2 ratio with respect to unstimulated cells. Conclusions In conclusion, capability of L. salivarius to modulate immune response was strictly strain dependent and strains of the same species might have opposite effects. Therefore, a careful evaluation of anti-inflammatory properties of lactobacilli should be performed on single strain, before any consideration on potential probiotic use. PMID:20184725

90-50-10 Celebration: Ernest Courant

ScienceCinema

Ernest Courant

2017-12-09

BNL hosts a celebration titled “90-50-10” to celebrate the 90th birthday of Ernest Courant (of “strong focusing” fame), the 50th anniversary of the startup of the Alternating Gradient Synchrotron (AGS, home of three Nobel Prizes), and the 10th anniversary of first collisions at the Relativistic Heavy Ion Collider (RHIC).

Near-Bottom Turbulence and Sediment Resuspension Induced by Nonlinear Internal Waves

DTIC Science & Technology

2012-09-30

boundary layer (BBL) turbulence and particulate resuspension leading to benthic nepheloid layer ( BNL ) formation. OBJECTIVES The specific objectives...capturing of nearbed particles by the BBL-turbulence and their transport/deposition into BNLs . • Analyze field observations from the New Jersey shelf to...generated resuspended particle distributions under NLIWs, a reliable proxy of BNLs , can be used to quantify the transmission or backscatter of optical

Addendum to strangeness production and color deconfinement

NASA Astrophysics Data System (ADS)

Castorina, P.; Plumari, S.; Satz, H.

Recent extensive data from the beam energy scan of the STAR collaboration at BNL-RHIC provide the basis for a detailed update for the universal behavior of the strangeness suppression factor γs as function of the initial entropy density as proposed in our recent paper (P. Castorina, S Plumari and H. Satz, Int. J. Mod. Phys. E 26 (2017) 1750081, arXiv:1709.02706 [nucl-th]).

Near-Bottom Turbulence and Sediment Resuspension Induced by Nonlinear Internal Waves

DTIC Science & Technology

2014-09-30

boundary layer (BBL) turbulence and particulate resuspension leading to benthic nepheloid layer ( BNL ) formation. OBJECTIVES The specific objectives...identify mechanisms for the capturing of near-bed particles by the BBL-turbulence and their transport/deposition into BNLs . • Analyze field...distributions under NLIWs, a reliable proxy of BNLs , can be used to quantify the transmission or backscatter of optical/acoustic signals of importance to

Archimedes' Oldest Writings Under X-ray vision (BNL Women in Science Lecture Series)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bergmann, Uwe

2009-05-20

Large parts of Archimedes’ writings were recently deciphered at the Stanford Synchrotron Radiation Lightsource at SLAC. A special x-ray technique showed maps of iron in faint traces of partially erased ink. The x-ray images revealed Archimedes’ writings from some of his most important works that were hidden by twelfth-century biblical texts, mold and forged gold paintings.

Long baseline neutrino oscillation experiment at the AGS. Physics design report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beavis, D.; Carroll, A.; Chiang, I.

1995-04-01

The authors present a design for a multi-detector long baseline neutrino oscillation experiment at the BNL AGS. It has been approved by the BNL-HENP-PAC as AGS Experiment 889. The experiment will search for oscillations in the {nu}{sub {mu}}, disappearance channel and the {nu}{sub {mu}} {leftrightarrow} {nu}{sub e} appearance channel by means of four identical neutrino detectors located 1, 3, 24, and 68km from the AGS neutrino source. Observed depletion of the {nu}{sub {mu}} flux (via quasi-elastic muon neutrino events, {nu}{sub {mu}}n {yields} {mu}{sup {minus}}p) in the far detectors not attended by an observed proportional increase of the {nu}{sub e} fluxmore » (via quasi-elastic electron neutrino events, {nu}{sub e}n {yields} e{sup {minus}}p) in those detectors will be prima facie evidence for the oscillation channel {nu}{sub {mu}} {leftrightarrow} {nu}{sub {tau}}. The experiment is directed toward exploration of the region of the neutrino oscillation parameters {Delta}m{sup 2} and sin{sup 2}2{theta}, suggested by the Kamiokande and IMB deep underground detectors but it will also explore a region more than two orders of magnitude larger than that of previous accelerator experiments. The experiment will run in a mode new to BNL. It will receive the fast extracted proton beam on the neutrino target approximately 20 hours per day when the AGS is not filling RHIC. A key aspect of the experimental design involves placing the detectors 1.5 degrees off the center line of the neutrino beam, which has the important advantage that the central value of the neutrino energy ({approx} 1 GeV) and the beam spectral shape are, to a good approximation, the same in all four detectors. The proposed detectors are massive, imaging, water Cherenkov detectors similar in large part to the Kamiokande and IMB detectors. The design has profited from their decade-long experience, and from the detector designs of the forthcoming SNO and SuperKamiokande detectors.« less

Proceedings of RIKEN BNL Research Center Workshop: Understanding QGP through Spectral Functions and Euclidean Correlators (Volume 89)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mocsy,A.; Petreczky, P.

2008-06-27

In the past two decades, one of the most important goals of the nuclear physics community has been the production and characterization of the new state of matter--Quark-Gluon Plasma (QGP). Understanding how properties of hadrons change in medium, particularly, the bound state of a very heavy quark and its antiquark, known as quarkonium, as well as determining the transport coefficients is crucial for identifying the properties of QGP and for the understanding of the experimental data from RHIC. On April 23rd, more than sixty physicists from twenty-seven institutions gathered for this three-day topical workshop held at BNL to discuss howmore » to understand the properties of the new state of matter obtained in ultra-relativistic heavy ion collisions (particularly at RHIC-BNL) through spectral functions. In-medium properties of the different particle species and the transport properties of the medium are encoded in spectral functions. The former could yield important signatures of deconfinement and chiral symmetry restoration at high temperatures and densities, while the later are crucial for the understanding of the dynamics of ultra-relativistic heavy ion collisions. Participants at the workshop are experts in various areas of spectral function studies. The workshop encouraged direct exchange of scientific information among experts, as well as between the younger and the more established scientists. The workshops success is evident from the coherent picture that developed of the current understanding of transport properties and in-medium particle properties, illustrated in the current proceedings. The following pages show calculations of meson spectral functions in lattice QCD, as well as implications of these for quarkonia melting/survival in the quark gluon plasma; Lattice calculations of the transport coefficients (shear and bulk viscosities, electric conductivity); Calculation of spectral functions and transport coefficients in field theories using weak coupling techniques; And certain spectral functions and also the heavy quark diffusion constant have been calculated in the strongly coupled limit of the N = 4 super-symmetric Yang Mills theory.« less

The Remarkable Change in Euro-American Cranial Shape and Size.

PubMed

Jantz, Richard L; Jantz, Lee Meadows

2016-01-01

Secular changes in stature, weight, or other components of the body that can be obtained from historical records have been extensively studied. Cranial change has been central to anthropology for more than a century, but the focus has normally been on change measured in centuries or millennia. Cranial change measured in decades, normally considered to result from plastic response to the environment, has been less studied. This article reports on change in cranial vault dimensions in white Americans. Variables were glabello-occipital length (GOL), basion-bregma height (BBH), basion-nasion length (BNL), maximum cranial breadth (XCB), and biauricular breadth (AUB). Cranial size was calculated as the geometric mean of these variables, and shape dimensions were calculated as described by Darroch and Mosimann ( 1985 ). Cranial module and cranial capacity were also calculated. Samples consisted of 1,112 males and 668 females complete for those variables. Samples were organized into 10-year birth cohorts, with birth years ranging from 1820 to 1990. One-way ANOVA was used to test for variation among cohorts. The pattern of secular change was examined graphically and was compared with quality-of-life and environmental indicators, including stature, infant mortality, calories per person, and relative number of immigrants. All variables showed significant secular change, but BBH, XCB, and BNL responded most strongly. Over the past 170 years, crania became relatively higher, narrower, and larger with longer cranial bases. Both sexes changed, but female change was less pronounced than male change. The cranial variables tracked secular changes in stature, most prominently BNL. The highest correlation between a cranial variable and quality-of-life indicator was BBH and infant mortality. We are not able to identify specific causes of secular changes in cranial morphology. However, given that modern Americans have introduced themselves into a novel environment never before experienced by human populations, we consider it unlikely that it is pure plasticity. In addition to possible plastic responses, it is likely that selection, acting through the dramatic changes in infant mortality, is also involved.

Near-Bottom Turbulence and Sediment Resuspension Induced by Nonlinear Internal Waves

DTIC Science & Technology

2015-05-27

leading to benthic nepheloid layer ( BNL ) formation. OBJECTIVES The specific objectives of this now-terminated project consisted of: • Using Large...particles by the BBL-turbulence and their transport/deposition into BNLs . • Analyze field observations from the New Jersey shelf to identify the...mapping. Finally, the generated resuspended particle distributions under NLIWs, a reliable proxy of BNLs , can be used to quantify the transmission or

Near Bottom Turbulence and Sediment Resuspension Induced by Nonlinear Internal Waves

DTIC Science & Technology

2013-09-30

boundary layer (BBL) turbulence and particulate resuspension leading to benthic nepheloid layer ( BNL ) formation. OBJECTIVES The specific...capturing of nearbed particles by the BBL-turbulence and their transport/deposition into BNLs . • Analyze field observations from the New Jersey shelf to...distributions under NLIWs, a reliable proxy of BNLs , can be used to quantify the transmission or backscatter of optical/acoustic signals of importance to

A new method to generate large order low temperature expansions for discrete spin models

NASA Astrophysics Data System (ADS)

Bhanot, Gyan

1993-03-01

I describe work done in collaboration with Michael Creutz at BNL and Jan Lacki at IAS Princeton. We have developed a method to generate very high order low temperature (weak coupling) expansions for discrete spin systems. For the 3-d and 4-d Ising model, we give results for the low temperature expansion of the average free energy to 50 and 44 excited bonds respectively.

Beam-energy dependence of charge balance functions from Au + Au collisions at energies available at the BNL Relativistic Heavy Ion Collider

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.

Balance functions have been measured in terms of relative pseudorapidity ( Δη ) for charged particle pairs at the BNL Relativistic Heavy Ion Collider (RHIC) from Au + Au collisions atmore » $$\\sqrt{s}$$$_{NN}$$ = 7.7 GeV to 200 GeV using the STAR detector. These results are compared with balance functions measured at the CERN Large Hadron Collider from Pb + Pb collisions at $$\\sqrt{s}$$$_{NN}$$ = 2.76 TeV by the ALICE Collaboration. The width of the balance function decreases as the collisions become more central and as the beam energy is increased. In contrast, the widths of the balance functions calculated using shuffled events show little dependence on centrality or beam energy and are larger than the observed widths. Balance function widths calculated using events generated by UrQMD are wider than the measured widths in central collisions and show little centrality dependence. The measured widths of the balance functions in central collisions are consistent with the delayed hadronization of a deconfined quark gluon plasma (QGP). Finally, the narrowing of the balance function in central collisions at $$\\sqrt{s}$$$_{NN}$$ = 7.7 GeV implies that a QGP is still being created at this relatively low energy.« less

Beam-energy dependence of charge balance functions from Au + Au collisions at energies available at the BNL Relativistic Heavy Ion Collider

NASA Astrophysics Data System (ADS)

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Banerjee, A.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandin, A. V.; Bunzarov, I.; Burton, T. P.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cervantes, M. C.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, J. H.; Chen, H. F.; Cheng, J.; Cherney, M.; Christie, W.; Codrington, M. J. M.; Contin, G.; Crawford, H. J.; Cui, X.; Das, S.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; Derradi de Souza, R.; di Ruzza, B.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Filip, P.; Fisyak, Y.; Flores, C. E.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A.; Hamed, A.; Han, L.-X.; Haque, R.; Harris, J. W.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, X.; Huang, H. Z.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z. H.; Kikola, D. P.; Kisel, I.; Kisiel, A.; Klein, S. R.; Koetke, D. D.; Kollegger, T.; Kosarzewski, L. K.; Kotchenda, L.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, Z. M.; Li, X.; Li, W.; Li, Y.; Li, X.; Li, C.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, G. L.; Ma, R. M.; Ma, Y. G.; Magdy, N.; Mahapatra, D. P.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; Minaev, N. G.; Mioduszewski, S.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V.; Olvitt, D. L.; Page, B. S.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlak, T.; Pawlik, B.; Pei, H.; Perkins, C.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Poskanzer, A. M.; Pruthi, N. K.; Przybycien, M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandacz, A.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Simko, M.; Skoby, M. J.; Smirnov, N.; Smirnov, D.; Solanki, D.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Summa, B. J.; Sun, X. M.; Sun, Z.; Sun, Y.; Sun, X.; Surrow, B.; Svirida, D. N.; Szelezniak, M. A.; Takahashi, J.; Tang, Z.; Tang, A. H.; Tarnowsky, T.; Tawfik, A. N.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Trzeciak, B. A.; Tsai, O. D.; Turnau, J.; Ullrich, T.; Underwood, D. G.; Upsal, I.; Van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Varma, R.; Vasconcelos, G. M. S.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, J. S.; Wang, X. L.; Wang, Y.; Wang, H.; Wang, F.; Wang, G.; Webb, G.; Webb, J. C.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z.; Xie, W.; Xin, K.; Xu, N.; Xu, Z.; Xu, H.; Xu, Y.; Xu, Q. H.; Yan, W.; Yang, Y.; Yang, C.; Yang, Y.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, X. P.; Zhang, Z. P.; Zhang, J. B.; Zhang, J. L.; Zhang, Y.; Zhang, S.; Zhao, F.; Zhao, J.; Zhong, C.; Zhu, Y. H.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.; STAR Collaboration

2016-08-01

Balance functions have been measured in terms of relative pseudorapidity (Δ η ) for charged particle pairs at the BNL Relativistic Heavy Ion Collider from Au + Au collisions at √{sNN}=7.7 GeV to 200 GeV using the STAR detector. These results are compared with balance functions measured at the CERN Large Hadron Collider from Pb + Pb collisions at √{sNN}=2.76 TeV by the ALICE Collaboration. The width of the balance function decreases as the collisions become more central and as the beam energy is increased. In contrast, the widths of the balance functions calculated using shuffled events show little dependence on centrality or beam energy and are larger than the observed widths. Balance function widths calculated using events generated by UrQMD are wider than the measured widths in central collisions and show little centrality dependence. The measured widths of the balance functions in central collisions are consistent with the delayed hadronization of a deconfined quark gluon plasma (QGP). The narrowing of the balance function in central collisions at √{sNN}=7.7 GeV implies that a QGP is still being created at this relatively low energy.

Experiments in intermediate energy physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dehnhard, D.

Research in experimental nuclear physics was done from 1979 to 2002 primarily at intermediate energy facilities that provide pion, proton, and kaon beams. Particularly successful has been the work at the Los Alamos Meson Physics Facility (LAMPF) on unraveling the neutron and proton contributions to nuclear ground state and transition densities. This work was done on a wide variety of nuclei and with great detail on the carbon, oxygen, and helium isotopes. Some of the investigations involved the use of polarized targets which allowed the extraction of information on the spin-dependent part of the triangle-nucleon interaction. At the Indiana Universitymore » Cyclotron Facility (IUCF) we studied proton-induced charge exchange reactions with results of importance to astrophysics and the nuclear few-body problem. During the first few years, the analysis of heavy-ion nucleus scattering data that had been taken prior to 1979 was completed. During the last few years we created hypernuclei by use of a kaon beam at Brookhaven National Laboratory (BNL) and an electron beam at Jefferson Laboratory (JLab). The data taken at BNL for a study of the non-mesonic weak decay of the A particle in a nucleus are still under analysis by our collaborators. The work at JLab resulted in the best resolution hypernuclear spectra measured thus far with magnetic spectrometers.« less

Biological Effects of Particles with Very High Energy Deposition on Mammalian Cells Utilizing the Brookhaven Tandem Van de Graaff Accelerator

NASA Technical Reports Server (NTRS)

Saha, Janapriya; Cucinotta, Francis A.; Wang, Minli

2013-01-01

High LET radiation from GCR (Galactic Cosmic Rays) consisting mainly of high charge and energy (HZE) nuclei and secondary protons and neutrons, and secondaries from protons in SPE (Solar Particle Event) pose a major health risk to astronauts due to induction of DNA damage and oxidative stress. Experiments with high energy particles mimicking the space environment for estimation of radiation risk are being performed at NASA Space Radiation Laboratory at BNL. Experiments with low energy particles comparing to high energy particles of similar LET are of interest for investigation of the role of track structure on biological effects. For this purpose, we report results utilizing the Tandem Van de Graaff accelerator at BNL. The primary objective of our studies is to elucidate the influence of high vs low energy deposition on track structure, delta ray contribution and resulting biological responses. These low energy ions are of special relevance as these energies may occur following absorption through the spacecraft and shielding materials in human tissues and nuclear fragments produced in tissues by high energy protons and neutrons. This study will help to verify the efficiency of these low energy particles and better understand how various cell types respond to them.

Beam-energy dependence of charge balance functions from Au + Au collisions at energies available at the BNL Relativistic Heavy Ion Collider

DOE PAGES

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; ...

2016-08-16

Balance functions have been measured in terms of relative pseudorapidity ( Δη ) for charged particle pairs at the BNL Relativistic Heavy Ion Collider (RHIC) from Au + Au collisions atmore » $$\\sqrt{s}$$$_{NN}$$ = 7.7 GeV to 200 GeV using the STAR detector. These results are compared with balance functions measured at the CERN Large Hadron Collider from Pb + Pb collisions at $$\\sqrt{s}$$$_{NN}$$ = 2.76 TeV by the ALICE Collaboration. The width of the balance function decreases as the collisions become more central and as the beam energy is increased. In contrast, the widths of the balance functions calculated using shuffled events show little dependence on centrality or beam energy and are larger than the observed widths. Balance function widths calculated using events generated by UrQMD are wider than the measured widths in central collisions and show little centrality dependence. The measured widths of the balance functions in central collisions are consistent with the delayed hadronization of a deconfined quark gluon plasma (QGP). Finally, the narrowing of the balance function in central collisions at $$\\sqrt{s}$$$_{NN}$$ = 7.7 GeV implies that a QGP is still being created at this relatively low energy.« less

Single-crystal Raman spectroscopy and X-ray crystallography at beamline X26-C of the NSLS

PubMed Central

Stoner-Ma, Deborah; Skinner, John M.; Schneider, Dieter K.; Cowan, Matt; Sweet, Robert M.; Orville, Allen M.

2011-01-01

Three-dimensional structures derived from X-ray diffraction of protein crystals provide a wealth of information. Features and interactions important for the function of macromolecules can be deduced and catalytic mechanisms postulated. Still, many questions can remain, for example regarding metal oxidation states and the interpretation of ‘mystery density’, i.e. ambiguous or unknown features within the electron density maps, especially at ∼2 Å resolutions typical of most macromolecular structures. Beamline X26-C at the National Synchrotron Light Source (NSLS), Brookhaven National Laboratory (BNL), provides researchers with the opportunity to not only determine the atomic structure of their samples but also to explore the electronic and vibrational characteristics of the sample before, during and after X-ray diffraction data collection. When samples are maintained under cryo-conditions, an opportunity to promote and follow photochemical reactions in situ as a function of X-ray exposure is also provided. Plans are in place to further expand the capabilities at beamline X26-C and to develop beamlines at NSLS-II, currently under construction at BNL, which will provide users access to a wide array of complementary spectroscopic methods in addition to high-quality X-ray diffraction data. PMID:21169688

Conclusions drawn from actions implemented within the first stage of the Cracow program of energy conservation and clean fossil fuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bieda, J.; Bardel, J.; Pierce, B.

1995-12-31

Since 1992 Brookhaven National Laboratory (BNL) and Pacific Northwest Laboratory (PNL), acting on behalf of the U.S. Department of Energy, executed the first stage of the Cracow Program of Energy Conservation and Clean Fossil Fuels, called also American-Polish Program of Actions for Elimination of Low Emission Sources in Cracow. The main contractor for BNL and PNL was the Cracow Development Office (BRK). The interest in improving the condition of Cracow air results from the fact that the standard for permissible air pollution was exceeded several times in Cracow and especially within the central part of the town. Therefore, air pollutionmore » appeared one of the most important problems that faced the municipal authorities. It followed from monitoring investigations that the high level of air pollutant concentration is caused by in-home coal-fired tile stoves operated in winter seasons and by coal- and coke-fired boiler houses simulated mainly in the central part of the town. The results obtained in first stage are presented. This paper is an attempt to formulate conclusions drawn from these works and recommendations with regard to the future policy of the town authorities; selected results are presented to clarify or illustrate the conclusions.« less

Speech privacy and annoyance considerations in the acoustic environment of passenger cars of high-speed trains.

PubMed

Jeon, Jin Yong; Hong, Joo Young; Jang, Hyung Suk; Kim, Jae Hyeon

2015-12-01

It is necessary to consider not only annoyance of interior noises but also speech privacy to achieve acoustic comfort in a passenger car of a high-speed train because speech from other passengers can be annoying. This study aimed to explore an optimal acoustic environment to satisfy speech privacy and reduce annoyance in a passenger car. Two experiments were conducted using speech sources and compartment noise of a high speed train with varying speech-to-noise ratios (SNRA) and background noise levels (BNL). Speech intelligibility was tested in experiment I, and in experiment II, perceived speech privacy, annoyance, and acoustic comfort of combined sounds with speech and background noise were assessed. The results show that speech privacy and annoyance were significantly influenced by the SNRA. In particular, the acoustic comfort was evaluated as acceptable when the SNRA was less than -6 dB for both speech privacy and noise annoyance. In addition, annoyance increased significantly as the BNL exceeded 63 dBA, whereas the effect of the background-noise level on the speech privacy was not significant. These findings suggest that an optimal level of interior noise in a passenger car might exist between 59 and 63 dBA, taking normal speech levels into account.

Exotic Meson Results from BNL E852

NASA Astrophysics Data System (ADS)

Manak, Joseph J.

1998-10-01

Results from BNL experiment 852 on exotic (non-q\\overlineq) meson production are presented. Production of final states with J^PC = 1^-+ is observed in π^-p interactions at 18 GeV/c in the ηπ^-, ρπ^- and η^'π^- channels. Since such states are manifestly exotic if they are resonant, we describe amplitude analyses which use the interference between these states and other well known states to measure the phase behavior of the J^PC = 1^-+ amplitudes. The analyses show that, in addition to the previously reported(D.R. Thompson et al.), Phys. Rev. Lett. 79, 1630 (1997) evidence for an exotic meson in the ηπ^- channel, there is strong evidence for a second exotic meson decaying to ρπ^- with a mass of M=1593 ±8^+29_-47 MeV/c^2 and a width of Γ=168 ±20^+150_-12 MeV/c^2. We also show that the η^'π^- system is dominated by J^PC = 1^-+ production and we use those data to determine decay branching ratios for the exotic mesons. Such measurements are expected to be crucial in determining the constituent nature of the exotic mesons - that is, whether they are consistent with being hybrid mesons or four-quark states.

Large scale accelerator production of 225Ac: Effective cross sections for 78-192MeV protons incident on 232Th targets.

PubMed

Griswold, J R; Medvedev, D G; Engle, J W; Copping, R; Fitzsimmons, J M; Radchenko, V; Cooley, J C; Fassbender, M E; Denton, D L; Murphy, K E; Owens, A C; Birnbaum, E R; John, K D; Nortier, F M; Stracener, D W; Heilbronn, L H; Mausner, L F; Mirzadeh, S

2016-12-01

Actinium-225 and 213 Bi have been used successfully in targeted alpha therapy (TAT) in preclinical and clinical research. This paper is a continuation of research activities aiming to expand the availability of 225 Ac. The high-energy proton spallation reaction on natural thorium metal targets has been utilized to produce millicurie quantities of 225 Ac. The results of sixteen irradiation experiments of thorium metal at beam energies between 78 and 192MeV are summarized in this work. Irradiations have been conducted at Brookhaven National Laboratory (BNL) and Los Alamos National Laboratory (LANL), while target dissolution and processing was carried out at Oak Ridge National Laboratory (ORNL). Excitation functions for actinium and thorium isotopes, as well as for some of the fission products, are presented. The cross sections for production of 225 Ac range from 3.6 to 16.7mb in the incident proton energy range of 78-192MeV. Based on these data, production of curie quantities of 225 Ac is possible by irradiating a 5.0gcm -2 232 Th target for 10 days in either BNL or LANL proton irradiation facilities. Copyright © 2016 Elsevier Ltd. All rights reserved.

Relationship between acceptance of background noise and hearing aid use

NASA Astrophysics Data System (ADS)

Nabelek, Anna K.; Burchfield, Samuel B.; Webster, Joanna D.

2003-04-01

Background noise produces complaints among hearing-aid users, however speech-perception-in-noise does not predict hearing-aid use. It is possible that hearing-aid users are complaining about the presence of background noise and not about speech perception. To test this possibility, acceptance of background noise is being investigated as a predictor of hearing-aid use. Acceptance of background noise is determined by having subjects select their most comfortable listening level (MCL) for a story. Next, speech-babble is added and the subjects select the maximum background noise level (BNL) which is acceptable while listening to and following the story. The difference between the MCL and the BNL is the acceptable noise level (ANL), all in dB. ANLs are being compared with hearing-aid use, subjective impressions of benefit (APHAB), speech perception in background noise (SPIN) scores, and audiometric data. Individuals who accept higher levels of background noise are more successful users than individuals who accept less background noise. Mean ANLs are 7.3 dB for full-time users (N=21), 12.6 dB for part-time users (N=44), and 13.8 dB for rejecters (N=17). ANLs are not related to APHAB, SPIN, or audiometric data. Results for about 120 subjects will be reported. [Work supported by NIDCD (NIH) RO1 DC 05018.

Intelligence and Law Enforcement: Countering Transnational Threats to the U.S.

DTIC Science & Technology

2001-12-03

University Press , 1989), pp. 133-203. 26 The history of the much-criticized domestic intelligence gathering is described in U.S. (continued...America, 1775-1980 (New Haven: Yale University Press , 1991). 27 U.S. Congress, 104th Congress, House of Representatives, Permanent Select Committee on...Involvement in the Banca Nazionale del Lavoro (BNL) Affair, Report, S. Prt. 103-12, February 1993, pp. 25-33; also, U.S. Congress, Senate, 102nd

The Center for Functional Nanomaterials at Brookhaven National Lab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dickerson, James

2015-07-09

Scientists from all over the world visit the Center for Functional Nanomaterials to explore strange phenomena hidden on the nanoscale—an exciting and powerful landscape spanning just billionths of a meter. The U.S. Department of Energy opened the CFN, one of its five nanoscale science research centers in the United States, to develop unprecedented energy technologies and solve fundamental scientific puzzles. Learn more about the CFN: https://www.bnl.gov/cfn/.

The Study of Advanced Accelerator Physics Research at UCLA Using the ATF at BNL: Vacuum Acceleration by Laser of Free Electrons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cline, David B.

An experiment was designed and data were taken to demonstrate that a tightly focused laser on vacuum can accelerate an electron beam in free space. The experiment was proof-of-principle and showed a clear effect for the laser beam off and on. The size of the effect was about 20% and was consistent over 30 laser and beam shots.

THE FIRST LASING OF 193 NM SASE, 4TH HARMONIC HGHG AND ESASE AT THE NSLS SDL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

WANG, X.J.; SHEN Y.; WATANABE, T.

2006-08-28

The first lasing of three types of single-pass high-gain FELs, SASE at 193 nm, 4th harmonic HGHG at 199 nm and ESASE at the Source Development Lab (SDL) of Brookhaven National Laboratory (BNL) is reported. The saturation of 4th harmonic HGHG and ESASE FELs was observed. We also observed the spectral broadening and instability of the 4th harmonic HGHG.

PREFACE: International Conference on Computing in High Energy and Nuclear Physics (CHEP 2012)

NASA Astrophysics Data System (ADS)

Ernst, Michael; Düllmann, Dirk; Rind, Ofer; Wong, Tony

2012-12-01

The International Conference on Computing in High Energy and Nuclear Physics (CHEP) was held at New York University on 21- 25 May 2012. CHEP is a major series of international conferences for physicists and computing professionals from the High Energy and Nuclear Physics community and related scientific and technical fields. The CHEP conference provides a forum to exchange information on computing progress and needs for the community, and to review recent, ongoing and future activities. CHEP conferences are held at roughly 18-month intervals, alternating between Europe, Asia, the Americas and other parts of the world. Recent CHEP conferences have been held in Taipei, Taiwan (2010); Prague, Czech Republic (2009); Victoria, Canada (2007); Mumbai, India (2006); Interlaken, Switzerland (2004); San Diego, United States (2003); Beijing, China (2001); Padova, Italy (2000). CHEP 2012 was organized by Brookhaven National Laboratory (BNL) and co-sponsored by New York University. The organizational structure for CHEP consists of an International Advisory Committee (IAC) which sets the overall themes of the conference, a Program Organizing Committee (POC) that oversees the program content, and a Local Organizing Committee (LOC) that is responsible for local arrangements (lodging, transportation and social events) and conference logistics (registration, program scheduling, conference site selection and conference proceedings). There were over 500 attendees with a program that included plenary sessions of invited speakers, a number of parallel sessions comprising around 125 oral and 425 poster presentations and industrial exhibitions. We thank all the presenters for the excellent scientific content of their contributions to the conference. Conference tracks covered topics on Online Computing, Event Processing, Distributed Processing and Analysis on Grids and Clouds, Computer Facilities, Production Grids and Networking, Software Engineering, Data Stores and Databases and Collaborative Tools. We would like to thank Brookhaven Science Associates, New York University, Blue Nest Events, the International Advisory Committee, the Program Committee and the Local Organizing Committee members for all their support and assistance. We also would like to acknowledge the support provided by the following sponsors: ACEOLE, Data Direct Networks, Dell, the European Middleware Initiative and Nexsan. Special thanks to the Program Committee members for their careful choice of conference contributions and enormous effort in reviewing and editing the conference proceedings. The next CHEP conference will be held in Amsterdam, the Netherlands on 14-18 October 2013. Conference Chair Michael Ernst (BNL) Program Committee Daniele Bonacorsi, University of Bologna, Italy Simone Campana, CERN, Switzerland Philippe Canal, Fermilab, United States Sylvain Chapeland, CERN, Switzerland Dirk Düllmann, CERN, Switzerland Johannes Elmsheuser, Ludwig Maximilian University of Munich, Germany Maria Girone, CERN, Switzerland Steven Goldfarb, University of Michigan, United States Oliver Gutsche, Fermilab, United States Benedikt Hegner, CERN, Switzerland Andreas Heiss, Karlsruhe Institute of Technology, Germany Peter Hristov, CERN, Switzerland Tony Johnson, SLAC, United States David Lange, LLNL, United States Adam Lyon, Fermilab, United States Remigius Mommsen, Fermilab, United States Axel Naumann, CERN, Switzerland Niko Neufeld, CERN, Switzerland Rolf Seuster, TRIUMF, Canada Local Organizing Committee Maureen Anderson, John De Stefano, Mariette Faulkner, Ognian Novakov, Ofer Rind, Tony Wong (BNL) Kyle Cranmer (NYU) International Advisory Committee Mohammad Al-Turany, GSI, Germany Lothar Bauerdick, Fermilab, United States Ian Bird, CERN, Switzerland Dominique Boutigny, IN2P3, France Federico Carminati, CERN, Switzerland Marco Cattaneo, CERN, Switzerland Gang Chen, Institute of High Energy Physics, China Peter Clarke, University of Edinburgh, United Kingdom Sridhara Dasu, University of Wisconsin-Madison, United States Günter Duckeck, Ludwig Maximilian University of Munich, Germany Richard Dubois, SLAC, United States Michael Ernst, BNL, United States Ian Fisk, Fermilab, United States Gonzalo Merino, PIC, Spain John Gordon, STFC-RAL, United Kingdom Volker Gülzow, DESY, Germany Frederic Hemmer, CERN, Switzerland Viatcheslav Ilyin, Moscow State University, Russia Nobuhiko Katayama, KEK, Japan Alexei Klimentov, BNL, United States Simon C. Lin, Academia Sinica, Taiwan Milos Lokajícek, FZU Prague, Czech Republic David Malon, ANL, United States Pere Mato Vila, CERN, Switzerland Mauro Morandin, INFN CNAF, Italy Harvey Newman, Caltech, United States Farid Ould-Saada, University of Oslo, Norway Ruth Pordes, Fermilab, United States Hiroshi Sakamoto, University of Tokyo, Japan Alberto Santoro, UERJ, Brazil Jim Shank, Boston University, United States Dongchul Son, Kyungpook National University, South Korea Reda Tafirout, TRIUMF, Canada Stephen Wolbers, Fermilab, United States Frank Wuerthwein, UCSD, United States

Distributed drift chamber design for rare particle detection in relativistic heavy ion collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bellwied, R.; Bennett, M.J.; Bernardo, V.

2001-10-02

This report describes a multi-plane drift chamber that was designed and constructed to function as a topological detector for the BNL AGSE896 rare particle experiment. The chamber was optimized for good spatial resolution, two track separation, and a high uniform efficiency while operating in a 1.6 Tesla magnetic field and subjected to long term exposure from a 11.6 GeV/nucleon beam of 10**6 Au ions per second.

Commissioning of the 112 MHz SRF Gun and 500 MHz bunching cavities for the CeC PoP Linac

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belomestnykh, S.; Ben-Zvi, I.; Brutus, J. C.

The Coherent electron Cooling Proof-of-Principle (CeC PoP) experiment at BNL includes a short electron linac. During Phase 1, a 112 MHz superconducting RF photo-emission gun and two 500 MHz normal conducting bunching cavities were installed and are under commissioning. The paper describes the Phase1 linac layout and presents commissioning results for the cavities and associated RF, cryogenic and other sub-systems

Intelligence and Law Enforcement: Countering Transnational Threats to the U.S.

DTIC Science & Technology

2001-12-03

K. Johnson, America’s Secret Power: the CIA in a Democratic Society (New York: Oxford University Press , 1989), pp. 133-203. 26 The history of the...gathering on civilians by the military is found in Joan M. Jensen, Army Surveillance in America, 1775-1980 (New Haven: Yale University Press , 1991). 27...103rd Congress, 1st session, Select Committee on Intelligence, The Intelligence Community’s Involvement in the Banca Nazionale del Lavoro (BNL

Influences of upwind emission sources and atmospheric processing on aerosol chemistry and properties at a rural location in the Northeastern U.S.: URBAN INFLUENCE ON RURAL AEROSOL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Shan; Collier, Sonya; Xu, Jianzhong

2016-05-19

Continuous real-time measurements of atmospheric aerosol with an Aerodyne High-Resolution Time-of-Flight Aerosol Mass Spectrometer (HR-AMS) coupled with a fast temperature-stepping thermodenuder were carried out in summer 2011 at Brookhaven National Laboratory (BNL, 40.871°N, 72.89°W) during the DOE Aerosol Life Cycle Intensive Operational Period (ALC-IOP) campaign.

Commissioning and Early Operation for the NSLS-II Booster RF System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marques, C.; Cupolo, J.; Davila, P.

2015-05-03

The National Synchrotron Light Source II (NSLS-II) at Brookhaven National Laboratory (BNL) is a third generation 3GeV, 500mA synchrotron light source. We discuss the booster synchrotron RF system responsible for providing power to accelerate an electron beam from 200MeV to 3GeV. The RF system design and construction are complete and is currently in the operational phase of the NSLS-II project. Preliminary operational data is also discussed.

The Center for Functional Nanomaterials at Brookhaven National Lab

ScienceCinema

Dickerson, James

2018-01-16

Scientists from all over the world visit the Center for Functional Nanomaterials to explore strange phenomena hidden on the nanoscale—an exciting and powerful landscape spanning just billionths of a meter. The U.S. Department of Energy opened the CFN, one of its five nanoscale science research centers in the United States, to develop unprecedented energy technologies and solve fundamental scientific puzzles. Learn more about the CFN: https://www.bnl.gov/cfn/.

Activities of the Solid State Physics Research Institute

NASA Technical Reports Server (NTRS)

1984-01-01

Three research programs are reviewed. These programs are muon spin rotation, studies of annealing in gallium arsenide and Hall effect studies in semiconductors. The muon spin rotation work centers around the development of a facility at the Alternating Gradient Synchrotron of BNL. Studies of annealing in GaAs concerns itself with the measurement of depolarization in GaAs. The Hall effect studies of proton damaged semiconductors provide new information on the nature of defects and dislocations in GaAs.

Current experiments in elementary particle physics. Revision

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galic, H.; Armstrong, F.E.; von Przewoski, B.

1994-08-01

This report contains summaries of 568 current and recent experiments in elementary particle physics. Experiments that finished taking data before 1988 are excluded. Included are experiments at BEPC (Beijing), BNL, CEBAF, CERN, CESR, DESY, FNAL, INS (Tokyo), ITEP (Moscow), IUCF (Bloomington), KEK, LAMPF, Novosibirsk, PNPI (St. Petersburg), PSI, Saclay, Serpukhov, SLAC, and TRIUMF, and also several underground and underwater experiments. Instructions are given for remote searching of the computer database (maintained under the SLAC/SPIRES system) that contains the summaries.

Superconducting 112 MHz QWR electron gun

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belomestnykh, S.; Ben-Zvi, I.; Boulware, C.H.

Brookhaven National Laboratory and Niowave, Inc. have designed and fabricated a superconducting 112 MHz quarter-wave resonator (QWR) electron gun. The first cold test of the QWR cryomodule has been completed at Niowave. The paper describes the cryomodule design, presents the cold test results, and outline plans to upgrade the cryomodule. Future experiments include studies of different photocathodes and use for the coherent electron cooling proof-of-principle experiment. Two cathode stalk options, one for multi-alkali photocathodes and the other one for a diamond-amplified photocathode, are discussed. A quarter-wave resonator concept of superconducting RF (SRF) electron gun was proposed at BNL for electronmore » cooling hadron beams in RHIC. QWRs can be made sufficiently compact even at low RF frequencies (long wavelengths). The long wavelength allows to produce long electron bunches, thus minimizing space charge effects and enabling high bunch charge. Also, such guns should be suitable for experiments requiring high average current electron beams. A 112 MHz QWR gun was designed, fabricated, and cold-tested in collaboration between BNL and Niowave. This is the lowest frequency SRF gun ever tested successfully. In this paper we describe the gun design and fabrication, present the cold test results, and outline our plans. This gun will also serve as a prototype for a future SRF gun to be used for coherent electron cooling of hadrons in eRHIC.« less

How hadron collider experiments contributed to the development of QCD: from hard-scattering to the perfect liquid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tannenbaum, M. J.

A revolution in elementary particle physics occurred during the period from the ICHEP1968 to the ICHEP1982 with the advent of the parton model from discoveries in Deeply Inelastic electron-proton Scattering at SLAC, neutrino experiments, hard-scattering observed in p+p collisions at the CERN ISR, the development of QCD, the discovery of the J/Ψ at BNL and SLAC and the clear observation of high transverse momentum jets at the CERN SPSmore » $$\\bar{p}$$ + p collider. These and other discoveries in this period led to the acceptance of QCD as the theory of the strong interactions. The desire to understand nuclear physics at high density such as in neutron stars led to the application of QCD to this problem and to the prediction of a Quark-Gluon Plasma (QGP) in nuclei at high energy density and temperatures. This eventually led to the construction of the Relativistic Heavy Ion Collider (RHIC) at BNL to observe superdense nuclear matter in the laboratory. This article discusses how experimental methods and results which confirmed QCD at the first hadron collider, the CERN ISR, played an important role in experiments at the first heavy ion collider, RHIC, leading to the discovery of the QGP as a perfect liquid as well as discoveries at RHIC and the LHC which continue to the present day.« less

How hadron collider experiments contributed to the development of QCD: from hard-scattering to the perfect liquid

DOE PAGES

Tannenbaum, M. J.

2018-01-30

A revolution in elementary particle physics occurred during the period from the ICHEP1968 to the ICHEP1982 with the advent of the parton model from discoveries in Deeply Inelastic electron-proton Scattering at SLAC, neutrino experiments, hard-scattering observed in p+p collisions at the CERN ISR, the development of QCD, the discovery of the J/Ψ at BNL and SLAC and the clear observation of high transverse momentum jets at the CERN SPSmore » $$\\bar{p}$$ + p collider. These and other discoveries in this period led to the acceptance of QCD as the theory of the strong interactions. The desire to understand nuclear physics at high density such as in neutron stars led to the application of QCD to this problem and to the prediction of a Quark-Gluon Plasma (QGP) in nuclei at high energy density and temperatures. This eventually led to the construction of the Relativistic Heavy Ion Collider (RHIC) at BNL to observe superdense nuclear matter in the laboratory. This article discusses how experimental methods and results which confirmed QCD at the first hadron collider, the CERN ISR, played an important role in experiments at the first heavy ion collider, RHIC, leading to the discovery of the QGP as a perfect liquid as well as discoveries at RHIC and the LHC which continue to the present day.« less

Open charm meson production at BNL RHIC within kt-factorization approach and revision of their semileptonic decays

NASA Astrophysics Data System (ADS)

Maciuła, Rafał; Szczurek, Antoni; Łuszczak, Marta

2015-09-01

We discuss inclusive production of open charm mesons in proton-proton scattering at the BNL RHIC. The calculation is performed in the framework of kt-factorization approach which effectively includes higher-order pQCD corrections. Different models of unintegrated gluon distributions (UGDF) from the literature are used. We focus on UGDF models favored by the LHC data and on a new up-to-date parametrizations based on the HERA collider deep-inelastic scattering high-precision data. Results of the kt-factorization approach are compared to next-to-leading order collinear predictions. The hadronization of heavy quarks is done by means of fragmentation function technique. The theoretical transverse momentum distributions of charmed mesons are compared with recent experimental data of the STAR collaboration at √{s }=200 and 500 GeV. Theoretical uncertainties related to the choice of renormalization and factorization scales as well as due to the quark mass are discussed. A very good description of the measured integrated cross sections and differential distributions is obtained for the Jung setB0 CCFM UGDF. Revised charm and bottom theoretical cross sections corresponding to those measured recently by the STAR and PHENIX collaborations for semileptonic decays of D and B mesons are presented. Significant improvement in theoretical description of the nonphotonic electrons measurements is clearly obtained with respect to the previous studies within the kt-factorization.

Welding consumable selection for cryogenic (4{degrees}K) application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kane, S.F.; Siewert, T.A.

1994-12-31

Brookhaven National Laboratory (BNL) has begun construction of a large (3.8 kilometer circumference) heavy ion collider for the Department of Energy. The collider uses superconducting magnets, operating at 4{degrees}K in supercritical helium, which meets the definition of a pressure vessel. The ASME Boiler & Pressure Vessel Code grants an exemption from impact testing to certain metals, but only for operating temperatures down to 20{degrees}K. Research and the latest change to ASTM Standard E23 have invalidated Charpy testing at 4{degrees}K, thus compliance with the Code is not possible. This effort was undertaken to identify the weld process and weld material necessarymore » to comply with the intent of the Code (impact test) requirements, that is, to design a weld joint that will assure adequate fracture toughness. We will report the results of this development and testing, and conclude that nitrogen and maganese enhanced 385L provides a superior weld metal for 4{degrees}K cryogenic applications without the exaggerated purity concerns normally associated with superaustenitic weld materials. This development has been so successful that BNL has procured 15,000 pounds of this material for magnet production. Oxygen content, manifested as inclusion density, has the single most significant effect upon fracture toughness and impact strength. Finally, we report that GMAW is a viable welding process, using off-the-shelf equipment, for 4{degrees}K cryogenic applications.« less

FRAMING Linguistics: ``SEANCES"(!!!) Martin-Bradshaw-Siegel ``Buzzwordism, Bandwagonism, Sloganeering For:Fun, Profit, Survival, Ego": Rampant UNethics Sociological-DYSfunctionality!!!

NASA Astrophysics Data System (ADS)

Bradshaw, John; Siegel, E.

2010-03-01

``Sciences''/SEANCES(!!!) rampant UNethics!!! WITNESS: Yau v Perelman Poincare-conj.-pf. [Naser, NewYorker(8/06)]; digits log- law Siegel[AMS Nat.Mtg.(02)-Abs.973-60-124] inversion to ONLY BEQS: Newcomb(1881)<<

Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma

PubMed Central

Liu, Wei-Lin; Gao, Ming; Tzen, Kai-Yuan; Tsai, Chiao-Ling; Hsu, Feng-Ming; Cheng, Ann-Lii; Cheng, Jason Chia-Hsien

2014-01-01

Tumor control of hepatocellular carcinoma by radiotherapy remains unsatisfactory. The phosphatidylinositol 3-kinase (PI3K)/Akt pathway plays a critical role in inhibiting cancer cell death. Elevated PI3K/Akt activity is associated with increased cellular resistance to irradiation. Our aim was to determine whether the inhibition of PI3K/Akt activity by a PI3K inhibitor, BKM120, contributes to the increased sensitivity of liver cancer cells to irradiation. The hepatocellular carcinoma cell lines (Huh7 and BNL) were used to evaluate the in vitro synergism between BKM120 and irradiation. Balb/c mice bearing ectopic BNL xenografts were treated with BKM120 and/or radiotherapy to assess the in vivo response. BKM120 increased cell killing by radiation, increased the expression of apoptotic markers, and suppressed the repair of radiation-induced DNA double-strand breaks. BKM120 pretreatment inhibited radiation-induced Akt phosphorylation and enhanced the tumor-suppressive effect and radiation-induced tumor cell apoptosis in ectopic xenografts. Inhibition of mTOR phosphorylation by rapamycin enhanced the radiosensitivity of BKM120-treated hepatocellular carcinoma cells. The synergism between BKM120 and irradiation likely inhibits the activation of Akt by radiation, leading to increased cell apoptosis and suppression of DNA-double-strand breaks repair in hepatocellular carcinoma cells. These data suggest that the BKM120/radiation combination may be a strategy worthy of clinical trials. PMID:25004403

Observations and simulations of the bottom nepheloid layer in the Lafourche Trough, Louisiana Continental Shelf

NASA Astrophysics Data System (ADS)

Jolliff, J.; Jarosz, E.; Penko, A.; Smith, T.

2017-12-01

The "Lafourche Trough" is a mud/silt -dominated, elongate seafloor depression located between transgressive sandy shoals approximately 50 km south of Cocodrie, Louisiana. These irregular bathymetric features are relicts of the abandoned Lafourche delta complex that still have an impact upon coupled sediment-hydrodynamic processes occurring today. Repeated optical and physical oceanographic surveys conducted during the spring of 2015 and winter 2017 reveal persistent bottom nepheloid layers (BNLs) characterized by extreme optical turbidity (beam attenuation 10 m-1, 532 nm). The manifestation and persistence of cohesive sediment BNLs in this area appears to result from a complex interplay between tidal currents, bathymetry, and frontal dynamics along the edge of the Mississippi River plume. Numerical experiments were performed using the Coupled Ocean Atmosphere Mesoscale Prediction System (COAMPS), an integrated air-sea-wave operational forecasting tool, that includes a simplified numerical sediment resuspension and transport scheme in order to simulate the nepheloid layer observations through the trough. The model results suggest that the wave-current bottom boundary layer is a critical factor in BNL development, and thusly, without wave model integration into COAMPS the system struggles to replicate the observations. Future modeling work will need to explore the potential suppression of physical mixing due to density perturbations along the BNL to fluid mud continuum within the bottom boundary layer.

Estimation of stopped protons at energies relevant for a beam energy scan at the BNL Relativistic Heavy Ion Collider

NASA Astrophysics Data System (ADS)

Thakur, Dhananjaya; Jakhar, Sunil; Garg, Prakhar; Sahoo, Raghunath

2017-04-01

The recent net-proton fluctuation results of the STAR (Solenoidal Tracker At RHIC) experiment from the beam energy scan (BES) program at the BNL Relativistic Heavy Ion Collider (RHIC) have drawn much attention to exploring the QCD critical point and the nature of deconfinement phase transition. There has been much speculation that the nonmonotonic behavior of κ σ2 of the produced protons around √{sN N} = 19.6 GeV in the STAR results may be due to the existence of a QCD critical point. However, the experimentally measured proton distributions contain protons from heavy resonance decays, from baryon stopping, and from direct production processes. These proton distributions are used to estimate the net-proton number fluctuation. Because it is difficult to disentangle the protons from the above-mentioned sources, it is better to devise a method which will account for the directly produced baryons (protons) to study the dynamical fluctuation at different center-of-mass energies. This is because it is assumed that any associated criticality in the system could affect the particle production mechanism and hence the dynamical fluctuation in various conserved numbers. In the present work, we demonstrate a method to estimate the number of stopped protons at RHIC BES energies for central 0-5% Au +Au collisions within STAR acceptance and discuss its implications on the net-proton fluctuation results.

Proceedings of RIKEN BNL Research Center Workshop

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samios, Nicholas P.

The twelfth evaluation of the RIKEN BNL Research Center (RBRC) took place on November 6 – 8, 2012 at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC), present at the meeting, were: Prof. Wit Busza, Prof. Miklos Gyulassy, Prof. Kenichi Imai, Prof. Richard Milner (Chair), Prof. Alfred Mueller, Prof. Charles Young Prescott, and Prof. Akira Ukawa. We are pleased that Dr. Hideto En’yo, the Director of the Nishina Institute of RIKEN, Japan, participated in this meeting both in informing the committee of the activities of the RIKEN Nishina Center for Accelerator- Based Science and the role ofmore » RBRC and as an observer of this review. In order to illustrate the breadth and scope of the RBRC program, each member of the Center made a presentation on his/her research efforts. This encompassed three major areas of investigation: theoretical, experimental and computational physics. In addition, the committee met privately with the fellows and postdocs to ascertain their opinions and concerns. Although the main purpose of this review is a report to RIKEN management on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment.« less

Mutagenic synergism detected between dimethyl sulfate and X-rays but not found between N-methyl-N-nitrosourea and X-rays in the stamen hairs of Tradescantia clone BNL 4430.

PubMed

Shima, N; Ichikawa, S

1995-09-01

Mutagenic interactions with X-rays of two monofunctional alkylating agents, dimethyl sulfate (DMS) and N-methyl-N-nitrosourea (MNU), were studied in the stamen hairs of Tradescantia clone BNL 4430, a blue/pink heterozygote. The young inflorescence-bearing shoots with roots cultivated in the nutrient solution circulating growth chamber were used as tester plants. Synergism between two different mutagens was judged to have occurred when the mutation frequency observed after applying the two mutagens concurrently was statistically significantly higher than the mutation frequency expected from the additive effects of the two mutagens. Clear synergistic effects in inducing somatic pink mutations were detected with all combinations of doses of DMS and X-rays examined, even in a relatively low X-ray dose range (down to 299 mGy), resembling those confirmed earlier between ethyl methanesulfonate (EMS) and X-rays, but somewhat differing from the synergisms observed earlier between methyl methanesulfonate (MMS) and X-rays. On the other hand, no mutagenic synergism was detected between MNU and X-rays, even in a relatively high X-ray dose range (up to 862 mGy). The presence or absence of mutagenic synergisms of these alkylating agents with X-rays could be related to the action mechanism of each alkylating agent.

How hadron collider experiments contributed to the development of QCD: from hard-scattering to the perfect liquid

NASA Astrophysics Data System (ADS)

Tannenbaum, M. J.

2018-05-01

A revolution in elementary particle physics occurred during the period from the ICHEP1968 to the ICHEP1982 with the advent of the parton model from discoveries in Deeply Inelastic electron-proton Scattering at SLAC, neutrino experiments, hard-scattering observed in p+p collisions at the CERN ISR, the development of QCD, the discovery of the J/ Ψ at BNL and SLAC and the clear observation of high transverse momentum jets at the CERN SPS p¯ + p collider. These and other discoveries in this period led to the acceptance of QCD as the theory of the strong interactions. The desire to understand nuclear physics at high density such as in neutron stars led to the application of QCD to this problem and to the prediction of a Quark-Gluon Plasma (QGP) in nuclei at high energy density and temperatures. This eventually led to the construction of the Relativistic Heavy Ion Collider (RHIC) at BNL to observe superdense nuclear matter in the laboratory. This article discusses how experimental methods and results which confirmed QCD at the first hadron collider, the CERN ISR, played an important role in experiments at the first heavy ion collider, RHIC, leading to the discovery of the QGP as a perfect liquid as well as discoveries at RHIC and the LHC which continue to the present day.

Personal Reflections on the Interaction of Science and Government and Possible Lessons for the Present Crisis (450th Brookhaven Lecture)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samios, Nicholas

2009-05-06

The 450th Brookhaven Lecture, to be held today, Wednesday, May 6, will be given by BNL Distinguished Senior Physicist Nicholas Samios, director of the RIKEN BNL Research Center and former Lab Director. Samios will discuss "Personal Reflections on the Interaction of Science and Government and Possible Lessons for the Present Crisis" at 4 p.m. in Berkner Hall. As many members of his prospective audience know, Samios's distinguished achievements in science and administration qualify him more than most to take on this topic. Having received his B.A. and Ph.D. degrees in physics from Columbia University in 1953 and 1957, respectively, hemore » joined the Lab in 1959. In addition to his work in experimental physics, he served as Physics Department Chair from 1975 to 81 and Deputy Director for High-Energy & Nuclear Physics from 1981 to 82. As a researcher, Samios made many of the particle discoveries that have helped define and lead to the acceptance of the "Standard Model" of particle physics, the accepted theory that explains known particle interactions. In particular, he is noted for the discovery of the phi meson and the omega minus hyperon, crucial elements delineating the symmetry of hadrons, which ultimately led to the quark model of elementary particles, a pillar of the Standard Model.« less

Proceedings of the 1997 oil heat technology conference and workshop

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDonald, R.J.

1997-09-01

This report documents the Proceedings of the 1997 Oil Heat Technology Conference and Workshop, held on April 3--4 at Brookhaven National Laboratory (BNL), and sponsored by the US Department of Energy--Office of Building Technologies, State and Community programs (DOE-BTS), in cooperation with the Petroleum Marketers Association of America (PMAA). This Conference is a key technology transfer activity supported by the ongoing Combustion Equipment Technology (Oil-Heat R and D) program at BNL, and is aimed at providing a forum for the exchange of information among international researchers, engineers, manufacturers, and marketers of oil-fired space-conditioning equipment. The objectives of the Conference weremore » to: identify and evaluate the state-of-the-art and recommend new initiatives for higher efficiency, a cleaner environment, and to satisfy consumer needs cost-effectively, reliably, and safely: and foster cooperation among federal and industrial representatives with the common goal of sustained national economic growth and energy security via energy conservation. The 1997 Oil Technology Conference comprised: (a) five plenary sessions devoted to presentations and summations by public and private sector industry representatives from the US, and Canada, and (b) four workshops which focused on mainstream issues in oil-heating technology. This book contains 14 technical papers and four summaries from the workshops. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database.« less

Report of the Snowmass M6 Working Group on high intensity proton sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weiren Chou and J. Wei

The U.S. high-energy physics program needs an intense proton source, a 1-4 MW Proton Driver (PD), by the end of this decade. This machine will serve as a stand-alone facility that will provide neutrino superbeams and other high intensity secondary beams such as kaons, muons, neutrons, and anti-protons (cf. E1 and E5 group reports) and also serve as the first stage of a neutrino factory (cf. M1 group report). It can also be a high brightness source for a VLHC. Based on present accelerator technology and project construction experience, it is both feasible and cost-effective to construct a 1-4 MWmore » Proton Driver. Two recent PD design studies have been made, one at FNAL and the other at the BNL. Both designed PD's for 1 MW proton beams at a cost of about U.S. $200M (excluding contingency and overhead) and both designs were upgradeable to 4 MW. An international collaboration between FNAL, BNL and KEK on high intensity proton facilities is addressing a number of key design issues. The superconducting (sc) RF cavities, cryogenics, and RF controls developed for the SNS can be directly adopted to save R&D efforts, cost, and schedule. PD studies are also actively being pursued at Europe and Japan.« less

An autologous in situ tumor vaccination approach for hepatocellular carcinoma. 2. Tumor-specific immunity and cure after radio-inducible suicide gene therapy and systemic CD40-ligand and Flt3-ligand gene therapy in an orthotopic tumor model.

PubMed

Kawashita, Yujo; Deb, Niloy J; Garg, Madhur K; Kabarriti, Rafi; Fan, Zuoheng; Alfieri, Alan A; Roy-Chowdhury, Jayanta; Guha, Chandan

2014-08-01

Diffuse hepatocellular carcinoma (HCC) is a lethal disease that radiation therapy (RT) currently has a limited role in treating because of the potential for developing fatal radiation-induced liver disease. However, recently diffuse HCC, "radio-inducible suicide gene therapy" has been shown to enhance local tumor control and residual microscopic disease within the liver for diffuse HCC, by using a combination of chemoactivation and molecular radiosensitization. We have demonstrated that the addition of recombinant adenovirus-expressing human Flt3 ligand (Adeno-Flt3L) after radio-inducible suicide gene therapy induced a Th1-biased, immune response and enhanced tumor control in an ectopic model of HCC. We hypothesized that sequential administration of recombinant adenovirus-expressing CD40L (Adeno-CD40L) could further potentiate the efficacy of our trimodal therapy with RT + HSV-TK + Adeno-Flt3L. We examined our hypothesis in an orthotopic model of diffuse HCC using BNL1ME A.7R.1 (BNL) cells in Balb/c mice. BNL murine hepatoma cells (5 × 10(4)) transfected with an expression vector of HSV-TK under the control of a radiation-inducible promoter were injected intraportally into BALB/cJ mice. Fourteen days after the HCC injection, mice were treated with a 25 Gy dose of radiation to the whole liver, followed by ganciclovir (GCV) treatment and systemic adenoviral cytokine gene therapy (Flt3L or CD40L or both). Untreated mice died in 27 ± 4 days. Radiation therapy alone had a marginal effect on survival (median = 35 ± 7 days) and the addition of HSV-TK/GCV gene therapy improved the median survival to 47 ± 6 days. However, the addition of Adeno-Flt3L to radiation therapy and HSV-TK/GCV therapy significantly (P = 0.0005) increased survival to a median of 63 ± 20 days with 44% (7/16) of the animals still alive 116 days after tumor implantation. The curative effect of Flt3L was completely abolished when using immunodeficient nude mice or mice depleted for CD4, CD8 and natural killer cells. The addition of Adeno-CD40L further improved the median survival of animals to 80 ± 15 days and this effect was abolished only when using anti-CD8 antibodies. Chromium-51 (51Cr) release assay showed cytotoxic T lymphocyte (CTL) activation, suggesting efficient dendritic cell (DC) activation with CTL activation after the treatment. Furthermore, when surviving mice were rechallenged with BNL-ETK cells on the foot pad, RT + HSV-TK/GCV + Flt3L + CD40L-treated mice developed a small tumor on day 56 but the tumor eventually disappeared after 105 days. Mice treated with RT + HSV-TK/GCV + Flt3L showed a slowed tumor growth curve compared with untreated mice. Therefore, combination therapy using Flt3L to induce DC proliferation and CD40L to enhance DC maturation holds great promise for immunomodulation of radiation therapy to enhance HCC tumor control and prevent progression of disease in patients with diffuse HCC.

How do emission patterns in megacities affect regional air pollution?

NASA Astrophysics Data System (ADS)

Heil, A.; Richter, C.; Schroeder, S.; Schultz, M. G.

2010-12-01

Megacities around the world show distinctly different emission patterns in terms of absolute amounts and emission ratios of individual chemical compounds due to varying socio-economic developments and technological standards. The emission patterns influence the chemical reactivity of the urban pollution plume, and hence determine air quality in and around megacity areas. In this study, which is part of the European project CITYZEN (megaCITY - Zoom for the ENvironment), the effects of emission changes in four selected megacity areas on air pollution were investigated: BeNeLux (BNL), Istanbul (IST), Pearl River Delta (PRD) and Sao Paulo (SAP). The study aims at answering the question: how would air pollution in megacity X change if it had the same urban emissions per capita as megacity Y? Model simulations with the global chemistry climate model ECHAM5-MOZ were carried out for the year 2001 using a resolution of about 2 degrees in the horizontal and of 31 levels (surface to 10 hPa) in the vertical. The model was driven by meteorological input data from the ECMWF ERA Interim reanalysis. Emissions were taken from the gridded global ACCMIP emission inventory recently established for use in chemistry-climate simulations in connection to the IPCC-AR5 assessments (Lamarque et al. 2010). We carried out sensitivity simulations where emission patterns from each of the megacity areas were replaced by those from all others. This was done on the basis of the per capita emissions for each species and sector averaged over the respective region. Total per capita CO and NMVOC emissions are highest in PRD and lowest in SAP while total per capita NOx emissions are highest in BNL and lowest in SAP. There are strong differences in the relative contribution of the urban sectors to total emissions of individual compounds. As a result, each of the four megacity areas exhibits a very characteristic NMVOC speciation profile which determines the NMVOC-related photochemical ozone (O_3) creation potential. Compared to the emissions used in the reference simulation, changing per capita urban emissions in BNL into those of IST or SAP will lead to reduction in total megacity emissions of CO and NOx by between 40 to 80% and of between 5 to 20% for NMVOC. When the per capita emissions for PRD are applied, only NOx decreases (by 50%) while CO and NMVOC increase by between 20 and 40%. Similar changes occur when the emissions are interchanged in the other three regions. Annual mean ambient O_3 concentrations in the entire BNL megacity domain are elevated by 3 to 8 ppb in all sensitivity runs and a significant effect is also found outside the main megacity area. In the IST and PRD megacity areas, O_3 levels increase or decrease by 1 to 5 ppb when the per capita emissions from the other regions are used. For the SAP megacity area, all scenarios lead to a reduction of annual mean O_3 levels by more than 4 ppb in the north-western section of the domain while increases up to 3 ppb are predicted for some southern regions. We will also present an analysis of changes in the photochemical regimes related to altered emission patterns. The study can contribute directly to the development of air pollution abatement strategies.

Weak decay of hypernuclei

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grace, R.

1983-01-01

The Moby Dick spectrometer (at BNL) in coincidence with a range spectrometer and a TOF neutron detector will be used to study the weak decay modes of /sup 12/C. The Moby Dick spectrometer will be used to reconstruct and tag events in which specific hypernuclear states are formed in the reaction K/sup -/ + /sup 12/C ..-->.. ..pi../sup -/ + /sup 12/C. Subsequent emission of decay products (pions, protons and neutrons) in coincidence with the fast forward pion will be detected in a time and range spectrometer, and a neutron detector.

Physical Chemistry of Reaction Dynamics in Ionic Liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Margulis, Claudio Javier

2016-10-31

The Margulis group BES funded research at the University of Iowa is part of a broader collaborative effort that includes the groups of Blank (U. Minnesota), Castner (Rutgers U.), Maroncelli (Penn. State U.) and Wishart (BNL). The goal of this group of PIs is to better understand from an experimental and a theoretical perspective different aspects of photo-initiated electron transfer processes in a set of different room-temperature ionic-liquid systems. The Margulis contribution is theoretical and computational. Details are presented in the attached documentation.

The New Big Science at the NSLS

NASA Astrophysics Data System (ADS)

Crease, Robert

2016-03-01

The term ``New Big Science'' refers to a phase shift in the kind of large-scale science that was carried out throughout the U.S. National Laboratory system, when large-scale materials science accelerators rather than high-energy physics accelerators became marquee projects at most major basic research laboratories in the post-Cold War era, accompanied by important changes in the character and culture of the research ecosystem at these laboratories. This talk explores some aspects of this phase shift at BNL's National Synchrotron Light Source.

Fiscal Year 2014 Annual Report on BNLs Next Generation Safeguards Initiative Human Capital Development Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pepper, Susan E.

2014-10-10

Brookhaven National Laboratory’s (BNL’s) Nonproliferation and National Security Department contributes to the National Nuclear Security Administration Office of Nonproliferation and International Security Next Generation Safeguards Initiative (NGSI) through university engagement, safeguards internships, safeguards courses, professional development, recruitment, and other activities aimed at ensuring the next generation of international safeguards professionals is adequately prepared to support the U.S. safeguards mission. This report is a summary of BNL s work under the NGSI program in Fiscal Year 2014.

From Flapping Birds to Space Telescopes: The Modern Science of Origami (BNL Women in Science Lecture)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lang, Robert J

2010-06-24

During the 1990s, the development and application of mathematical techniques to origami revolutionized this centuries-old Japanese art of paper folding. In his talk, Lang will describe how geometric concepts led to the solution of a broad class of origami-folding problems. Conversely, algorithms and theorems of origami design have shed light on long-standing mathematical questions and have solved practical engineering problems. Lang will discuss how origami has led to huge space telescopes, safer airbags, and more.

X-Ray Crystallographic Studies on Acetylcholinesterase and on Its Interaction with Anticholinesterase Agents.

DTIC Science & Technology

1994-11-24

complexes with reversible ligands, including edrophonium, d-tubocurarine and huperzine A , diffracting to similar resolution. The X26c Laue beam line...The EMBL-DESY synchrotron facility at Hamburg was employed to collect a complete 2.3 A data set for a crystal of native Torpedo AChE, as well as for...at the NSLS synchrotron facility at Brookhaven National Laboratory (BNL) was used to obtain a Laue diffraction pattern for a crystal of native Torpedo

Characterization of an 800 nm SASE FEL at Saturation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuhn, Heinz-Dieter

2002-11-13

VISA (Visible to Infrared SASE Amplifier) is an FEL (Free Electron Laser) designed to saturate at a radiation wavelength of 800 nm within a 4-m long, strong focusing undulator. Large gain is achieved by driving the FEL with the 72 MeV, high brightness beam of BNL's Accelerator Test Facility (ATF). We present measurements that demonstrate saturation in addition to the frequency spectrum of the FEL radiation. Energy, gain length and spectral characteristics are compared and shown to agree with simulation and theoretical predictions.

∆ E /∆ E Measurements of Energetic Ions Using CVD Diamond Detectors

DOE PAGES

Alghamdi, Ahmed; Heilbronn, Lawrence; Castellanos, Luis A.; ...

2018-06-20

Experimental and computational results of a Δ E /Δ E diamond detection system are presented. The Δ E /Δ E detection system was evaluated using energetic proton and iron beams striking thick polyethylene targets at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL). The measured data for diamond sensor A show good agreement with the Geant4 simulation. In addition, simulations have demonstrated the ability to identify hydrogen isotopes using a diamond detection system.

∆ E /∆ E Measurements of Energetic Ions Using CVD Diamond Detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alghamdi, Ahmed; Heilbronn, Lawrence; Castellanos, Luis A.

Experimental and computational results of a Δ E /Δ E diamond detection system are presented. The Δ E /Δ E detection system was evaluated using energetic proton and iron beams striking thick polyethylene targets at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL). The measured data for diamond sensor A show good agreement with the Geant4 simulation. In addition, simulations have demonstrated the ability to identify hydrogen isotopes using a diamond detection system.

Wounded-quark emission function at the top energy available at the BNL Relativistic Heavy Ion Collider

NASA Astrophysics Data System (ADS)

Barej, Michał; Bzdak, Adam; Gutowski, Paweł

2018-03-01

The wounded nucleon and quark emission functions are extracted for different centralities in d +Au collisions at √{s }=200 GeV using Monte Carlo simulations and experimental data. The shape of the emission function depends on centrality in the wounded nucleon model, whereas it is practically universal (within uncertainties) in the wounded quark model. Predictions for d Nc h/d η distributions in p +Au and 3He+Au collisions are presented.

Anti p and anti Lambda production in Si + Au collisions at the AGS

NASA Technical Reports Server (NTRS)

Wu, Yue-Dong

1996-01-01

(anti (ital p)) and (anti (Lambda)) production in central Si + Au collisions has been measured by E589 at the BNL-AGS. Preliminary (ital m)(sub (perpendicular)) spectra are presented for (anti (ital p))'s and (anti (Lambda))'s. The (ital dn/dy) distribution for (anti (ital p))'s is also presented. Based on the (anti (ital p)) and (anti (Lambda)) measurements, (anti (Lambda))/(anti (ital p)) ratios are calculated in the rapidity range of 1.1-1.5.

Hyperon polarization in heavy-ion collisions and holographic gravitational anomaly

NASA Astrophysics Data System (ADS)

Baznat, Mircea; Gudima, Konstantin; Sorin, Alexander; Teryaev, Oleg

2018-04-01

We study the energy dependence of global polarization of Λ hyperons in peripheral Au-Au collisions. We combine the calculation of vorticity and strange chemical potential in the framework of the kinetic quark-gluon-string model with the anomalous mechanism related to the axial vortical effect. We pay special attention to the temperature-dependent contribution related to the holographic gravitational anomaly and find that the preliminary data from the BNL Relativistic Heavy Ion Collider are compatible with its suppression discovered earlier in lattice calculations.

Nucleon structure from 2+1-flavor domain-wall QCD

NASA Astrophysics Data System (ADS)

Ohta, Shigemi

2018-03-01

Nucleon-structure calculations of isovector vector-and axialvector-current form factors, transversity and scalar charge, and quark momentum and helicity fractions are reported from two recent 2+1-flavor dynamical domain-wall fermions lattice-QCD ensembles generated jointly by the RIKEN-BNL-Columbia and UKQCD Collaborations with Iwasaki × dislocation-suppressing-determinatn-ratio gauge action at inverse lattice spacing of 1.378(7) GeV and pion mass values of 249.4(3) and 172.3(3) MeV.

Event reweighting with the NuWro neutrino interaction generator

NASA Astrophysics Data System (ADS)

Pickering, Luke; Stowell, Patrick; Sobczyk, Jan

2017-09-01

Event reweighting has been implemented in the NuWro neutrino event generator for a number of free theory parameters in the interaction model. Event reweighting is a key analysis technique, used to efficiently study the effect of neutrino interaction model uncertainties. This opens up the possibility for NuWro to be used as a primary event generator by experimental analysis groups. A preliminary model tuning to ANL and BNL data of quasi-elastic and single pion production events was performed to validate the reweighting engine.

Direct photon elliptic flow at energies available at the BNL Relativistic Heavy Ion Collider and the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

Kim, Young-Min; Lee, Chang-Hwan; Teaney, Derek; Zahed, Ismail

2017-07-01

We use an event-by-event hydrodynamical description of the heavy-ion collision process with Glauber initial conditions to calculate the thermal emission of photons. The photon rates in the hadronic phase follow from a spectral function approach and a density expansion, while in the partonic phase they follow from the Arnold-Moore-Yaffe (AMY) perturbative rates. The calculated photon elliptic flows are lower than those reported recently by both the ALICE and PHENIX collaborations.

Current Experiments in Particle Physics. 1996 Edition.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galic, Hrvoje

2003-06-27

This report contains summaries of current and recent experiments in Particle Physics. Included are experiments at BEPC (Beijing), BNL, CEBAF, CERN, CESR, DESY, FNAL, Frascati, ITEP (Moscow), JINR (Dubna), KEK, LAMPF, Novosibirsk, PNPI (St. Petersburg), PSI, Saclay, Serpukhov, SLAC, and TRIUMF, and also several proton decay and solar neutrino experiments. Excluded are experiments that finished taking data before 1991. Instructions are given for the World Wide Web (WWW) searching of the computer database (maintained under the SLAC-SPIRES system) that contains the summaries.

Workshop on detectors for third-generation synchrotron sources: Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-12-01

The aims of the workshop were (1) to acquaint APS users with current R and D being carried out on detectors, (2) to identify new detector systems possible during the next five years, (3) to identify new detectors theoretically possible in the future, (4) to stimulate interactions between user groups and detector developers, and (5) to obtain recommendations from expert panels on technical issues needing resolution. Development of detectors at ESRF, Spring-8, BNL, CERN and LBL are included.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Philippacopoulos, A.J.; Shaukat, S.K.; Chokshi, N.C.

During the first quarter of 1988, the Nuclear Regulatory Commission (NRC) prepared a proposed Revision 2 to the NUREG-0800 Standard Review Plan (SRP) Sections 2.5.2 (Vibratory Ground Motion), 3.7.1 (Seismic Design Parameters), 3.7.2 (Seismic Systems Analysis) and 3.7.3 (Seismic Subsystem Analysis). The proposed Revision 2 to the SRP was a result of many years' work carried out by the NRC and the nuclear industry on the Unresolved Safety Issue (USI) A-40: ''Seismic Design Criteria.'' The background material related to NRC's efforts for resolving the A-40 issue is described in NUREG-1233. In June 1988, the proposed Revision 2 of the SRPmore » was issued by NRC for public review and comments. Comments were received from Sargent and Lundy Engineers, Westinghouse Electric Corporation, Stevenson and Associates, Duke Power Company, General Electric Company and Electric Power Research Institute. In September 1988, Brookhaven National Laboratory (BNL) and its consultants (C.J. Costantino, R.P. Kennedy, J. Stevenson, M. Shinozuka and A.S. Veletsos) were requested to carry out a review of the comments received from the above six organizations. The objective of this review was to assist the NRC staff with the evaluation and resolution of the public comments. This review was initiated during October 1988 and it was completed on January 1989. As a result of this review, a set of modifications to the above mentioned sections of the SRP were recommended by BNL and its consultants. This paper summarizes the recommended modifications. 4 refs.« less

PanDA Pilot Submission using Condor-G: Experience and Improvements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao X.; Hover John; Wlodek Tomasz

2011-01-01

PanDA (Production and Distributed Analysis) is the workload management system of the ATLAS experiment, used to run managed production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA 'AutoPilot' scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison.more » In this paper, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resulting from this collaboration, including isolation of site-based issues by running a separate Gridmanager for each remote site, introduction of the 'Nonessential' job attribute to allow Condor to optimize its behavior for the specific character of pilot jobs, better understanding and handling of the Gridmonitor process, as well as better scheduling in the PanDA pilot scheduler component. We will also cover the monitoring of the health of the system.« less

Young inflorescence-bearing shoots with roots of Tradescantia clone BNL 4430 cultivated in nutrient solution circulating systems: an alternative to potted plants and cuttings for mutagenicity tests.

PubMed

Shima, N; Xiao, L Z; Sakuramoto, F; Ichikawa, S

1997-12-12

The use of young inflorescence-bearing shoots with roots of Tradescantia clone BNL 4430 cultivated in a nutrient solution circulating (NSC) growth chamber was tested and developed as an alternative method for using Tradescantia plants in mutagenicity testings. The NSC growth chamber was designed for our requirements, based on trial cultivations of the shoots with roots in its smaller-sized prototype. The nutrient solution used was a 1/2500 Hyponex solution. The characteristics of this clone, i.e., many new shoots constantly emerging from the basal nodes one after another and its short height favorable for early flowering, made it possible to prepare many young inflorescence-bearing shoots with roots at one time. A simplified NSC cultivation system could also be developed at a lower cost, and by using it together with the NSC growth chamber, recycling of untreated materials was established for supplying steadily enough amounts of young inflorescence-bearing shoots with roots for mutagenicity testings. Compared with traditional methods of using potted plants or cuttings, the new method exhibited more stable flower production, better stamen-hair growth and a significantly lower spontaneous (background) mutation frequency, and could produce more inflorescences per space. The use of such young inflorescence-bearing shoots with roots was therefore judged to be satisfactory to serve as a new mutagenicity test system alternating with potted plants and cuttings.

Spectra and elliptic flow of thermal photons from full-overlap U+U collisions at energies available at the BNL Relativistic Heavy Ion Collider

NASA Astrophysics Data System (ADS)

Dasgupta, Pingal; Chatterjee, Rupa; Srivastava, Dinesh K.

2017-06-01

We calculate pT spectra and elliptic flow for tip-tip and body-body configurations of full-overlap uranium-uranium (U+U ) collisions by using a hydrodynamic model with smooth initial density distribution and compare the results with those obtained from Au+Au collisions at the BNL Relativistic Heavy Ion Collider (RHIC). Production of thermal photons is seen to be significantly larger for tip-tip collisions compared with body-body collisions of uranium nuclei in the region pT>1 GeV. The difference in the results for the two configurations of U+U collisions depends on the initial energy deposition which is yet to be constrained precisely from hadronic measurements. The thermal photon spectrum from body-body collisions is found to be close to the spectrum from most-central Au+Au collisions at RHIC. The elliptic-flow parameter calculated for body-body collisions is found to be large and comparable to the v2(pT) for mid-central collisions of Au nuclei. On the other hand, as expected, v2(pT) is close to zero for tip-tip collisions. The qualitative nature of the photon spectra and elliptic flow for the two different orientations of uranium nuclei is found to be independent of the initial parameters of the model calculation. We show that the photon results from fully overlapping U+U collisions are complementary to the results from Au+Au collisions at RHIC.

FGF /FGFR Signal Induces Trachea Extension in the Drosophila Visual System

PubMed Central

Chu, Wei-Chen; Lee, Yuan-Ming; Henry Sun, Yi

2013-01-01

The Drosophila compound eye is a large sensory organ that places a high demand on oxygen supplied by the tracheal system. Although the development and function of the Drosophila visual system has been extensively studied, the development and contribution of its tracheal system has not been systematically examined. To address this issue, we studied the tracheal patterns and developmental process in the Drosophila visual system. We found that the retinal tracheae are derived from air sacs in the head, and the ingrowth of retinal trachea begin at mid-pupal stage. The tracheal development has three stages. First, the air sacs form near the optic lobe in 42-47% of pupal development (pd). Second, in 47-52% pd, air sacs extend branches along the base of the retina following a posterior-to-anterior direction and further form the tracheal network under the fenestrated membrane (TNUFM). Third, the TNUFM extend fine branches into the retina following a proximal-to-distal direction after 60% pd. Furthermore, we found that the trachea extension in both retina and TNUFM are dependent on the FGF(Bnl)/FGFR(Btl) signaling. Our results also provided strong evidence that the photoreceptors are the source of the Bnl ligand to guide the trachea ingrowth. Our work is the first systematic study of the tracheal development in the visual system, and also the first study demonstrating the interactions of two well-studied systems: the eye and trachea. PMID:23991208

Inhibitory effect of plant-originated glycoprotein (27 kDa) on expression of matrix metalloproteinase-9 in cadmium chloride-induced BNL CL.2 cells.

PubMed

Lee, Jin; Lim, Kye-Taek

2011-12-01

Cadmium is very harmful to the environment and to human beings because of its long lifetime. The toxicity of cadmium as an industrial pollutant and a food contaminant, and as one of the major components in cigarette smoke is well known. Cadmium can cause a number of lesions in many organs, such as the kidney, the lung, the liver, the brain, the blood system. However, the mechanism of toxicity of cadmium is not yet clear. Also, it has been well known as human carcinogen which is indirectly caused inflammation-mediated hepatocarcinoma. In the present study it was demonstrated that glycoprotein (27 kDa) isolated from Gardenia jasminoides Ellis (GJE) protects BNL CL.2 cells from expression of inflammation-related factors stimulated by cadmium chloride (10 μM). Intracellular ROS and intracellular Ca(2+) using fluorescence, activities of activator protein (AP)-1, cyclooxygenase (COX)-2, matrix metalloproteinase (MMP)-9, and arachidonic acid (AA) using immunoblot analysis or radioactivity were evaluated. The results obtained from this experiment indicated that GJE glycoprotein (100 μg/mL) inhibits the production of intracellular ROS, and intracellular Ca(2+) mobilization. Also, it significantly suppressed inflammatory factors [expression of AP-1 (c-Jun and c-Fos), arachidonic acid, COX-2, and MMP-9]. Taken together, these findings suggest that GJE glycoprotein might be used for protection of inflammation caused by cadmium ion as one of natural compounds. Copyright © 2011 Elsevier GmbH. All rights reserved.

Drosophila glypican Dally-like acts in FGF-receiving cells to modulate FGF signaling during tracheal morphogenesis

PubMed Central

Yan, Dong; Lin, Xinhua

2007-01-01

Summary Previous studies in Drosophila have shown that heparan sulfate proteoglycans (HSPGs) are involved in both breathless (btl)- and heartless (htl)-mediated FGF signaling during embryogenesis. However, the mechanism(s) by which HSPGs control Btl and Htl signaling is unknown. Here we show that dally-like (dlp, a Drosophila glypican) mutant embryos exhibit severe defects in tracheal morphogenesis and show a reduction in btl-mediated FGF signaling activity. However, htl-dependent mesodermal cell migration is not affected in dlp mutant embryos. Furthermore, expression of Dlp, but not other Drosophila HSPGs, can restore effectively the tracheal morphogenesis in dlp embryos. Rescue experiments in dlp embryos demonstrate that Dlp functions only in Bnl/FGF receiving cells in a cell-autonomous manner, but is not essential for Bnl/FGF expression cells. To further dissect the mechanism(s) of Dlp in Btl signaling, we analyzed the role of Dlp in Btl-mediated air sac tracheoblast formation in wing discs. Mosaic analysis experiments show that removal of HSPG activity in FGF-producing or other surrounding cells does not affect tracheoblasts migration, while HSPG mutant tracheoblast cells fail to receive FGF signaling. Together, our results argue strongly that HSPGs regulate Btl signaling exclusively in FGF-receiving cells as co-receptors, but are not essential for the secretion and distribution of the FGF ligand. This mechanism is distinct from HSPG functions in morphogen distribution, and is likely a general paradigm for HSPG functions in FGF signaling in Drosophila. PMID:17959166

Polarimetry of the polarized hydrogen deuteride HDice target under an electron beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laine, Vivien E.

2013-10-01

The study of the nucleon structure has been a major research focus in fundamental physics in the past decades and still is the main research line of the Thomas Jefferson National Accelerator Facility (Jefferson Lab). For this purpose and to obtain statistically meaningful results, having both a polarized beam and a highly efficient polarized target is essential. For the target, this means high polarization and high relative density of polarized material. A Hydrogen Deuteride (HD) target that presents both such characteristics has been developed first at Brookhaven National Lab (BNL) and brought to the Hall B of Jefferson Lab inmore » 2008. The HD target has been shown to work successfully under a high intensity photon beam (BNL and Jefferson Lab). However, it remained to be seen if the target could stand an electron beam of reasonably high current (nA). In this perspective, the target was tested for the first time in its frozen spin mode under an electron beam at Jefferson Lab in 2012 during the g14 experiment. This dissertation presents the principles and usage procedures of this HD target. The polarimetry of this target with Nuclear Magnetic Resonance (NMR) during the electron beam tests is also discussed. In addition, this dissertation also describes another way to perform target polarimetry with the elastic scattering of electrons off a polarized target by using data taken on helium-3 during the E97-110 experiment that occurred in Jefferson Lab's Hall A in 2003.« less

INEL BNCT Research Program annual report, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Venhuizen, J.R.

1993-05-01

This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1992. Contributions from all the principal investigators about their individual projects are included, specifically, chemistry (pituitary tumor targeting compounds, boron drug development including liposomes, lipoproteins, and carboranylalanine derivatives), pharmacology (murine screenings, toxicity testing, inductively coupled plasma-atomic emission spectroscopy (ICP-AES) analysis of biological samples), physics (radiation dosimetry software, neutron beam and filter design, neutron beam measurement dosimetry), and radiation biology (small and large animal models tissue studies and efficacy studies). Information on the potentialmore » toxicity of borocaptate sodium and boronophenylalanine is presented, results of 21 spontaneous-tumor-bearing dogs that have been treated with BNCT at the Brookhaven National Laboratory (BNL) Medical Research Reactor (BMRR) are discussed, and predictions for an epithermal-neutron beam at the Georgia Tech Research Reactor (GTRR) are shown. Cellular-level boron detection and localization by secondary ion mass spectrometry, sputter-initiated resonance ionization spectroscopy, low atomization resonance ionization spectroscopy, and alpha track are presented. Boron detection by ICP-AES is discussed in detail. Several boron carrying drugs exhibiting good tumor uptake are described. Significant progress in the potential of treating pituitary tumors with BNCT is presented. Measurement of the epithermal-neutron flux at BNL and comparison to predictions are shown. Calculations comparing the GTRR and BMRR epithermal-neutron beams are also presented. Individual progress reports described herein are separately abstracted and indexed for the database.« less

HFE Process Guidance and Standards for potential application to updating NRC guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacques Hugo; J. J. Persensky

2012-07-01

The U.S. Nuclear Regulatory Commission (NRC) reviews and evaluates the human factors engineering (HFE) programs of applicants for nuclear power plant construction permits, operating licenses, standard design certifications, and combined operating licenses. The purpose of these safety reviews is to help ensure that personnel performance and reliability are appropriately supported. Detailed design review procedures and guidance for the evaluations is provided in three key documents: the Standard Review Plan (NUREG-0800), the HFE Program Review Model (NUREG-0711), and the Human-System Interface Design Review Guidelines (NUREG-0700). These documents were last revised in 2007, 2004 and 2002, respectively. The NRC is committed tomore » the periodic update and improvement of these guidance documents to ensure that they remain state-of-the-art design evaluation tools. Thus, the NRC has initiated a project with BNL to update the NRC guidance to remain current with recent research on human performance, advances in HFE methods and tools, and new technology. INL supported Brookhaven National Lab (BNL) to update the detailed HFE review criteria contained in NUREG-0711 and NUREG-0700 based on (1) feedback obtained from end users, (2) the results of NRC research and development efforts supporting the NRC staff’s HFE safety reviews, and (3) other material the project staff identify as applicable to the update effort. INL submitted comments on development plans and sections of NUREGs 0800, 0711, and 0700. The contractor prepared the report attached here as the deliverable for this work.« less

Electronic Desorption of gas from metals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molvik, A W; Kollmus, H; Mahner, E

During heavy ion operation in several particle accelerators world-wide, dynamic pressure rises of orders of magnitude were triggered by lost beam ions that bombarded the vacuum chamber walls. This ion-induced molecular desorption, observed at CERN, GSI, and BNL, can seriously limit the ion beam lifetime and intensity of the accelerator. From dedicated test stand experiments we have discovered that heavy-ion induced gas desorption scales with the electronic energy loss (dE{sub e}/dx) of the ions slowing down in matter; but it varies only little with the ion impact angle, unlike electronic sputtering.

Construction and operation of a support facilities (Building 729) for operation/testing of a prototype accelerator/storage ring (XLS) and machine shop for the National Synchrotron Light Source at Brookhaven National Laboratory, Upton, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-06-01

Proposed action is to construct at BNL a 5,600-ft[sup 2] support building, install and operate a prototypic 200 MeV accelerator and a prototypic 700 MeV storage ring within, and to construct and operate a 15 kV substation to power the building. The accelerator and storage ring would comprise the x-ray lithography source or XLS.

Construction and operation of a support facilities (Building 729) for operation/testing of a prototype accelerator/storage ring (XLS) and machine shop for the National Synchrotron Light Source at Brookhaven National Laboratory, Upton, New York. Environmental assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-06-01

Proposed action is to construct at BNL a 5,600-ft{sup 2} support building, install and operate a prototypic 200 MeV accelerator and a prototypic 700 MeV storage ring within, and to construct and operate a 15 kV substation to power the building. The accelerator and storage ring would comprise the x-ray lithography source or XLS.

Indications of conical emission of charged hadrons at the BNL relativistic heavy ion collider.

PubMed

Abelev, B I; Aggarwal, M M; Ahammed, Z; Anderson, B D; Arkhipkin, D; Averichev, G S; Bai, Y; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Baumgart, S; Beavis, D R; Bellwied, R; Benedosso, F; Betts, R R; Bhardwaj, S; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Biritz, B; Bland, L C; Bombara, M; Bonner, B E; Botje, M; Bouchet, J; Braidot, E; Brandin, A V; Bruna, E; Bueltmann, S; Burton, T P; Bystersky, M; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Callner, J; Catu, O; Cebra, D; Cendejas, R; Cervantes, M C; Chajecki, Z; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, J Y; Cheng, J; Cherney, M; Chikanian, A; Choi, K E; Christie, W; Chung, S U; Clarke, R F; Codrington, M J M; Coffin, J P; Cormier, T M; Cosentino, M R; Cramer, J G; Crawford, H J; Das, D; Dash, S; Daugherity, M; De Silva, C; de Moura, M M; Dedovich, T G; Dephillips, M; Derevschikov, A A; de Souza, R Derradi; Didenko, L; Djawotho, P; Dogra, S M; Dong, X; Drachenberg, J L; Draper, J E; Du, F; Dunlop, J C; Dutta Mazumdar, M R; Edwards, W R; Efimov, L G; Elhalhuli, E; Elnimr, M; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Eun, L; Fachini, P; Fatemi, R; Fedorisin, J; Feng, A; Filip, P; Finch, E; Fine, V; Fisyak, Y; Gagliardi, C A; Gaillard, L; Gangadharan, D R; Ganti, M S; Garcia-Solis, E; Ghazikhanian, V; Ghosh, P; Gorbunov, Y N; Gordon, A; Grebenyuk, O; Grosnick, D; Grube, B; Guertin, S M; Guimaraes, K S F F; Gupta, A; Gupta, N; Guryn, W; Haag, B; Hallman, T J; Hamed, A; Harris, J W; He, W; Heinz, M; Heppelmann, S; Hippolyte, B; Hirsch, A; Hjort, E; Hoffman, A M; Hoffmann, G W; Hofman, D J; Hollis, R S; Huang, H Z; Humanic, T J; Igo, G; Iordanova, A; Jacobs, P; Jacobs, W W; Jakl, P; Jin, F; Jones, P G; Joseph, J; Judd, E G; Kabana, S; Kajimoto, K; Kang, K; Kapitan, J; Kaplan, M; Keane, D; Kechechyan, A; Kettler, D; Khodyrev, V Yu; Kiryluk, J; Kisiel, A; Klein, S R; Knospe, A G; Kocoloski, A; Koetke, D D; Kopytine, M; Kotchenda, L; Kouchpil, V; Kravtsov, P; Kravtsov, V I; Krueger, K; Krus, M; Kuhn, C; Kumar, L; Kurnadi, P; Lamont, M A C; Landgraf, J M; Lapointe, S; Lauret, J; Lebedev, A; Lednicky, R; Lee, C-H; Levine, M J; Li, C; Li, Y; Lin, G; Lin, X; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, H; Liu, J; Liu, L; Ljubicic, T; Llope, W J; Longacre, R S; Love, W A; Lu, Y; Ludlam, T; Lynn, D; Ma, G L; Ma, Y G; Mahapatra, D P; Majka, R; Mall, O I; Mangotra, L K; Manweiler, R; Margetis, S; Markert, C; Matis, H S; Matulenko, Yu A; McShane, T S; Meschanin, A; Millane, J; Miller, M L; Minaev, N G; Mioduszewski, S; Mischke, A; Mitchell, J; Mohanty, B; Molnar, L; Morozov, D A; Munhoz, M G; Nandi, B K; Nattrass, C; Nayak, T K; Nelson, J M; Nepali, C; Netrakanti, P K; Ng, M J; Nogach, L V; Nurushev, S B; Odyniec, G; Ogawa, A; Okada, H; Okorokov, V; Olson, D; Pachr, M; Page, B S; Pal, S K; Pandit, Y; Panebratsev, Y; Pawlak, T; Peitzmann, T; Perevoztchikov, V; Perkins, C; Peryt, W; Phatak, S C; Planinic, M; Pluta, J; Poljak, N; Poskanzer, A M; Potukuchi, B V K S; Prindle, D; Pruneau, C; Pruthi, N K; Putschke, J; Raniwala, R; Raniwala, S; Ray, R L; Reed, R; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Rose, A; Roy, C; Ruan, L; Russcher, M J; Rykov, V; Sahoo, R; Sakrejda, I; Sakuma, T; Salur, S; Sandweiss, J; Sarsour, M; Schambach, J; Scharenberg, R P; Schmitz, N; Seger, J; Selyuzhenkov, I; Seyboth, P; Shabetai, A; Shahaliev, E; Shao, M; Sharma, M; Shi, S S; Shi, X-H; Sichtermann, E P; Simon, F; Singaraju, R N; Skoby, M J; Smirnov, N; Snellings, R; Sorensen, P; Sowinski, J; Spinka, H M; Srivastava, B; Stadnik, A; Stanislaus, T D S; Staszak, D; Strikhanov, M; Stringfellow, B; Suaide, A A P; Suarez, M C; Subba, N L; Sumbera, M; Sun, X M; Sun, Y; Sun, Z; Surrow, B; Symons, T J M; Szanto de Toledo, A; Takahashi, J; Tang, A H; Tang, Z; Tarnowsky, T; Thein, D; Thomas, J H; Tian, J; Timmins, A R; Timoshenko, S; Tlusty, D; Tokarev, M; Trainor, T A; Tram, V N; Trattner, A L; Trentalange, S; Tribble, R E; Tsai, O D; Ulery, J; Ullrich, T; Underwood, D G; Van Buren, G; van Leeuwen, M; Vander Molen, A M; Vanfossen, J A; Varma, R; Vasconcelos, G M S; Vasilevski, I M; Vasiliev, A N; Videbaek, F; Vigdor, S E; Viyogi, Y P; Vokal, S; Voloshin, S A; Wada, M; Waggoner, W T; Wang, F; Wang, G; Wang, J S; Wang, Q; Wang, X; Wang, X L; Wang, Y; Webb, J C; Westfall, G D; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Wu, Y; Xu, N; Xu, Q H; Xu, Y; Xu, Z; Yepes, P; Yoo, I-K; Yue, Q; Zawisza, M; Zbroszczyk, H; Zhan, W; Zhang, H; Zhang, S; Zhang, W M; Zhang, Y; Zhang, Z P; Zhao, Y; Zhong, C; Zhou, J; Zoulkarneev, R; Zoulkarneeva, Y; Zuo, J X

2009-02-06

Three-particle azimuthal correlation measurements with a high transverse momentum trigger particle are reported for pp, d+Au, and Au+Au collisions at sqrt[s_{NN}]=200 GeV by the STAR experiment. Dijet structures are observed in pp, d+Au and peripheral Au+Au collisions. An additional structure is observed in central Au+Au data, signaling conical emission of correlated charged hadrons. The conical emission angle is found to be theta=1.37+/-0.02(stat)-0.07+0.06(syst), independent of p_{ perpendicular}.

Photon interferometry of Au+Au collisions at the BNL Relativistic Heavy-Ion Collider.

PubMed

Bass, Steffen A; Müller, Berndt; Srivastava, Dinesh K

2004-10-15

We calculate the two-body correlation function of direct photons produced in central Au+Au collisions at the Relativistic Heavy-Ion Collider. Our calculation includes contributions from the early preequilibrium phase in which photons are produced via hard parton scatterings as well as radiation of photons from a thermalized quark-gluon plasma and the subsequent expanding hadron gas. We find that high energy photon interferometry provides a faithful probe of the details of the space-time evolution and of the early reaction stages of the system.

Report on Quality Control Review of the Deloitte & Touche, LLP and Defense Contract Audit Agency FY 2008 Single Audit of The Aerospace Corporation

DTIC Science & Technology

2010-10-29

Auounlants’ lI<:<:ounl~ LS’ Slal.-mt31 . enLS nts on ~’" Audiling i[i !! St3nd:IrIJ. ’a , bnls S~cllon CI] 316. t , MCons~Co sitliJ"<’,."lion...8217e Bnl /lch Mal/ager. Suulh /lay .Bmnch OjJia .. Def~".~e C(Jn/roc, Audll Agfncy, prOl"idi! $Ioffper/m·mfng Circular .... ] JJ o!l</ir /o’lno/lraini

NNDC Data Services

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tuli, J.K.; Sonzogni,A.

The National Nuclear Data Center has provided remote access to some of its resources since 1986. The major databases and other resources available currently through NNDC Web site are summarized. The National Nuclear Data Center (NNDC) has provided remote access to the nuclear physics databases it maintains and to other resources since 1986. With considerable innovation access is now mostly through the Web. The NNDC Web pages have been modernized to provide a consistent state-of-the-art style. The improved database services and other resources available from the NNOC site at www.nndc.bnl.govwill be described.

Putting tools in the toolbox: Development of a free, open-source toolbox for quantitative image analysis of porous media.

NASA Astrophysics Data System (ADS)

Iltis, G.; Caswell, T. A.; Dill, E.; Wilkins, S.; Lee, W. K.

2014-12-01

X-ray tomographic imaging of porous media has proven to be a valuable tool for investigating and characterizing the physical structure and state of both natural and synthetic porous materials, including glass bead packs, ceramics, soil and rock. Given that most synchrotron facilities have user programs which grant academic researchers access to facilities and x-ray imaging equipment free of charge, a key limitation or hindrance for small research groups interested in conducting x-ray imaging experiments is the financial cost associated with post-experiment data analysis. While the cost of high performance computing hardware continues to decrease, expenses associated with licensing commercial software packages for quantitative image analysis continue to increase, with current prices being as high as $24,000 USD, for a single user license. As construction of the Nation's newest synchrotron accelerator nears completion, a significant effort is being made here at the National Synchrotron Light Source II (NSLS-II), Brookhaven National Laboratory (BNL), to provide an open-source, experiment-to-publication toolbox that reduces the financial and technical 'activation energy' required for performing sophisticated quantitative analysis of multidimensional porous media data sets, collected using cutting-edge x-ray imaging techniques. Implementation focuses on leveraging existing open-source projects and developing additional tools for quantitative analysis. We will present an overview of the software suite that is in development here at BNL including major design decisions, a demonstration of several test cases illustrating currently available quantitative tools for analysis and characterization of multidimensional porous media image data sets and plans for their future development.

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP ON RHIC SPIN PHYSICS III AND IV, POLARIZED PARTONS AT HIGH Q2 REGION, AUGUST 3, 2000 AT BNL, OCTOBER 14, 2000 AT KYOTO UNIVERSITY.

DOE Office of Scientific and Technical Information (OSTI.GOV)

BUNCE, G.; VIGDOR, S.

2001-03-15

International workshop on II Polarized Partons at High Q2 region 11 was held at the Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto, Japan on October 13-14, 2000, as a satellite of the international conference ''SPIN 2000'' (Osaka, Japan, October 16-21,2000). This workshop was supported by RIKEN (The Institute of Physical and Chemical Research) and by Yukawa Institute. The scientific program was focused on the upcoming polarized collider RHIC. The workshop was also an annual meeting of RHIC Spin Collaboration (RSC). The number of participants was 55, including 28 foreign visitors and 8 foreign-resident Japanese participants, reflecting the international naturemore » of the RHIC spin program. At the workshop there were 25 oral presentations in four sessions, (1) RHIC Spin Commissioning, (2) Polarized Partons, Present and Future, (3) New Ideas on Polarization Phenomena, (4) Strategy for the Coming Spin Running. In (1) the successful polarized proton commissioning and the readiness of the accelerator for the physics program impressed us. In (2) and (3) active discussions were made on the new structure function to be firstly measured at RHIC, and several new theoretical ideas were presented. In session (4) we have established a plan for the beam time requirement toward the first collision of polarized protons. These proceedings include the transparencies presented at the workshop. The discussion on ''Strategy for the Coming Spin Running'' was summarized by the chairman of the session, S. Vigdor and G. Bunce.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lemley, James; Furey, Michael

The BNL Microelectronics group has designed a series of custom ASICs in CMOS technol­ogy for use with Cadmium-Zink-Telluride (CdZnTe) radiation detectors, primarily in the field of nuclear spectroscopy. An increased demand for CdZnTe based detection systems that can operate in high flux X-ray inspection equipment makes it necessary to develop a new type of signal processing ASIC, one which can achieve moderate energy resolution at very high count rate. This work covers the development of a high-rate, low power ASIC that classifies events into one of five energy windows at rates up to 2 MHz/channel.

Contributions to the mini-workshop on beam-beam compensation in the Tevatron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shiltsev, V.

1998-02-01

The purpose of the Workshop was to assay the current understanding of compensation of the beam-beam effects in the Tevatron with use of low-energy high-current electron beam, relevant accelerator technology, along with other novel techniques of the compensation and previous attempts. About 30 scientists representing seven institutions from four countries--FNAL, SLAC, BNL, Novosibirsk, CERN, and Dubna were in attendance. Twenty one talks were presented. The event gave firm ground for wider collaboration on experimental test of the compensation at the Tevatron collider. This report consists of vugraphs of talks given at the meeting.

{sigma} Hyperons in the Nucleus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bart, S.; Chrien, R. E.; Franklin, W. A.

1999-12-20

A search for {sigma} hypernuclear states in p -shell hypernuclei has been performed with the Moby Dick spectrometer and the low energy separated beam (LESB-2) at the Brookhaven Alternating Gradient Synchrotron (BNL AGS). Unlike some previously published reports, no narrow states have been observed for targets of {sup 6}Li and {sup 9}Be in (K{sup -}, {pi}{sup {+-}}) reactions, either for bound state or continuum regions. Together with the previously reported J=0 , T=1/2 bound state in {sup 4}{sub {sigma}} He , these results demonstrate the crucial role of isospin in {sigma} hypernuclei. (c) 1999 The American Physical Society.

It's No Secret: Fifty-eight Years of National Security Programs at BNL (463rd Brookhaven Lecture)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Indusi, Joseph

2010-11-17

Prepare for a true tale of suspense and international intrigue. A tale that began in 1952, continued through the Cold War, and is not yet complete today. A tale of unexpected allies. Hear the true tale of one Laboratory’s efforts to keep nuclear materials out of the hands of evildoers. Freidlander. Higinbotham. Dodson. Kouts. And many more! See some of BNL’s all-star cast in the defining roles that shaped their careers as they worked toward keeping the nation and the world safe from the proliferation of nuclear weapons.

Heavy-ion induced electronic desorption of gas from metals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molvik, A W; Kollmus, H; Mahner, E

During heavy ion operation in several particle accelerators world-wide, dynamic pressure rises of orders of magnitude were triggered by lost beam ions that bombarded the vacuum chamber walls. This ion-induced molecular desorption, observed at CERN, GSI, and BNL, can seriously limit the ion beam lifetime and intensity of the accelerator. From dedicated test stand experiments we have discovered that heavy-ion induced gas desorption scales with the electronic energy loss (dE{sub e}/d/dx) of the ions slowing down in matter; but it varies only little with the ion impact angle, unlike electronic sputtering.

Initial eccentricity in deformed {sup 197}Au+{sup 197}Au and {sup 238}U+{sup 238}U collisions at {radical}(s{sub NN})=200 GeV at the BNL Relativistic Heavy Ion Collider

DOE Office of Scientific and Technical Information (OSTI.GOV)

Filip, Peter; Lednicky, Richard; Masui, Hiroshi

2009-11-15

Initial eccentricity and eccentricity fluctuations of the interaction volume created in relativistic collisions of deformed {sup 197}Au and {sup 238}U nuclei are studied using optical and Monte Carlo (MC) Glauber simulations. It is found that the nonsphericity noticeably influences the average eccentricity in central collisions, and eccentricity fluctuations are enhanced from deformation. Quantitative results are obtained for Au+Au and U+U collisions at energy {radical}(s{sub NN})=200 GeV.

Overview of the NASA space radiation laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

La Tessa, Chiara; Sivertz, Michael; Chiang, I-Hung

The NASA Space Radiation Laboratory (NSRL) is a multidisciplinary center for space radiation research funded by NASA and located at the Brookhaven National Laboratory (BNL), Upton NY. Operational since 2003, the scope of NSRL is to provide ion beams in support of the NASA Humans in Space program in radiobiology, physics and engineering to measure the risk and ameliorate the effect of radiation in space. Recently, it has also been recognized as the only facility in the U.S. currently capable of contributing to heavy ion radiotherapy research. Finally, this work contains a general overview of NSRL structure, capabilities and operation.

Overview of the NASA space radiation laboratory

DOE PAGES

La Tessa, Chiara; Sivertz, Michael; Chiang, I-Hung; ...

2016-11-11

The NASA Space Radiation Laboratory (NSRL) is a multidisciplinary center for space radiation research funded by NASA and located at the Brookhaven National Laboratory (BNL), Upton NY. Operational since 2003, the scope of NSRL is to provide ion beams in support of the NASA Humans in Space program in radiobiology, physics and engineering to measure the risk and ameliorate the effect of radiation in space. Recently, it has also been recognized as the only facility in the U.S. currently capable of contributing to heavy ion radiotherapy research. Finally, this work contains a general overview of NSRL structure, capabilities and operation.

Using a commercial mathematics software package for on-line analysis at the BNL Accelerator Test Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malone, R.; Wang, X.J.

BY WRITING BOTH A CUSTOM WINDOWS(NTTM) DYNAMIC LINK LIBRARY AND GENERIC COMPANION SERVER SOFTWARE, THE INTRINSIC FUNCTIONS OF MATHSOFT MATHCAD(TM) HAVE BEEN EXTENDED WITH NEW CAPABILITIES WHICH PERMIT DIRECT ACCESS TO THE CONTROL SYSTEM DATABASES OF BROOKHAVEN NATIONAL LABORATORY ACCELERATOR TEST FACILITY. UNDER THIS SCHEME, A MATHCAD WORKSHEET EXECUTING ON A PERSONAL COMPUTER BECOMES A CLIENT WHICH CAN BOTH IMPORT AND EXPORT DATA TO A CONTROL SYSTEM SERVER VIA A NETWORK STREAM SOCKET CONNECTION. THE RESULT IS AN ALTERNATIVE, MATHEMATICALLY ORIENTED VIEW OF CONTROLLING THE ACCELERATOR INTERACTIVELY.

Modeling Electronegative Impurity Concentrations in Liquid Argon Detectors

NASA Astrophysics Data System (ADS)

Tang, Wei; Li, Yichen; Thorn, Craig; Qian, Xin

2017-01-01

Achieving long electron lifetime is crucial to reach the high performance of large Liquid Argon Time Projection Chamber (LArTPC) envisioned for next generation neutrino experiments. We have built up a quantitative model to describe the impurity distribution and transportation in a cryostat. Henrys constants of Oxygen and water, which describe the partition of impurities between gas argon and liquid argon, have been deduced through this model with the measurements in BNL 20-L LAr test stand. These results indicate the importance of the gas purification system and prospects on large LArTPC detectors will be discussed.

Array Detector Modules for Spent Fuel Verification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bolotnikov, Aleksey

Brookhaven National Laboratory (BNL) proposes to evaluate the arrays of position-sensitive virtual Frisch-grid (VFG) detectors for passive gamma-ray emission tomography (ET) to verify the spent fuel in storage casks before storing them in geo-repositories. Our primary objective is to conduct a preliminary analysis of the arrays capabilities and to perform field measurements to validate the effectiveness of the proposed array modules. The outcome of this proposal will consist of baseline designs for the future ET system which can ultimately be used together with neutrons detectors. This will demonstrate the usage of this technology in spent fuel storage casks.

Λ hyperon polarization in relativistic heavy ion collisions from a chiral kinetic approach

NASA Astrophysics Data System (ADS)

Sun, Yifeng; Ko, Che Ming

2017-08-01

Using a chiral kinetic approach based on initial conditions from a multiphase transport model, we study the spin polarizations of quarks and antiquarks in noncentral heavy ion collisions at the BNL Relativistic Heavy Ion Collider. Because of the nonvanishing vorticity field in these collisions, quarks and antiquarks are found to acquire appreciable spin polarizations in the direction perpendicular to the reaction plane. Converting quarks and antiquarks to hadrons via the coalescence model, we further calculate the spin polarizations of Λ and anti-Λ hyperons and find their values comparable to those measured in experiments by the STAR Collaboration.

X-Ray Topography of Tetragonal Lysozyme Grown by the Temperature-Controlled Technique

NASA Technical Reports Server (NTRS)

Stojanoff, V.; Siddons, D. P.; Monaco, Lisa A.; Vekilov, Peter; Rosenberger, Franz

1997-01-01

Growth-induced defects in lysozyme crystals were observed by white-beam and monochromatic X-ray topography at the National Synchrotron Light Source (NSLS) at the Brookhaven National Laboratory (BNL). The topographic methods were non-destructive to the extent that traditional diffraction data collection could be performed to high resolution after topography. It was found that changes in growth parameters, defect concentration as detected by X-ray topography, and the diffraction quality obtainable from the crystals were all strongly correlated. In addition, crystals with fewer defects showed lower mosaicity and higher diffraction resolution as expected.

Critical opacity: a possible explanation of the fast thermalization times seen in BNL RHIC experiments.

PubMed

Gastineau, F; Blanquier, E; Aichelin, J

2005-07-29

The Nambu-Jona-Lasinio Lagrangian offers an explication of the seemingly contradictory observations that (a) the energy loss in the entrance channel of heavy ion reactions is not sufficient to thermalize the system and that (b) the observed hadron cross sections are in almost perfect agreement with hydrodynamical calculations. According to this scenario, a critical opacity develops close to the chiral phase transition which equilibrates and hadronizes the expanding system very effectively. It creates as well radial flow and, if the system is not isotropic, finite upsilon2 values.

Experimental Overview of the Search for Chiral Effects at RHIC

NASA Astrophysics Data System (ADS)

Wang, Gang

2017-01-01

In high-energy heavy-ion collisions, various novel transport phenomena in local chiral domains result from the interplay of quantum anomalies with magnetic field and vorticity, and could survive the expansion of the fireball and be detected in experiments. Among these phenomena are the chiral magnetic effect, the chiral vortical effect and the chiral magnetic wave, the experimental searches for which have aroused extensive interest. This review will describe the current status of experimental studies at Relativistic Heavy Ion Collider at BNL, and outline the future work in experiment needed to eliminate the existing uncertainties in the interpretation of the data.

Metal hydride reasearch and development program at Brookhaven National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, J.R.; Reilly, J.J.

1978-01-01

A progress report is presented covering work performed in the hydrogen materials development program at Brookhaven National Laboratory (BNL) for FY78 which encompasses the time period from October 1, 1977 through September 30, 1978. The subjects to be discussed here concern properties of importance in the utilization of metal hydrides as energy storage media. Most of the areas of research were initiated prior to FY78, however all of the results contained in this manuscript were obtained during the aforementioned period of time. The following subjects will be discussed: the properties of ferro-titanium and chrome-titanium alloy hydrides.

Integration of DAS (distributed acoustic sensing) vertical seismic profile and geostatistically modeled lithology data to characterize an enhanced geothermal system.

NASA Astrophysics Data System (ADS)

Cronin, S. P.; Trainor Guitton, W.; Team, P.; Pare, A.; Jreij, S.; Powers, H.

2017-12-01

In March 2016, a 4-week field data acquisition took place at Brady's Natural Lab (BNL), an enhanced geothermal system (EGS) in Fallan, NV. During these 4 weeks, a vibe truck executed 6,633 sweeps, recorded by nodal seismometers, horizontal distributed acoustic sensing (DAS) cable, and 400 meters of vertical DAS cable. DAS provides lower signal to noise ratio than traditional geophones but better spatial resolution. The analysis of DAS VSP included Fourier transform, and filtering to remove all up-going energy. Thus, allowing for accurate first arrival picking. We present an example of the Gradual Deformation Method (GDM) using DAS VSP and lithological data to produce a distribution of valid velocity models of BNL. GDM generates continuous perturbations of prior model realizations seeking the best match to the data (i.e. minimize the misfit). Prior model realizations honoring the lithological data were created using sequential Gaussian simulation, a commonly used noniterative geostatistical method. Unlike least-squares-based methods of inversion, GDM readily incorporates a priori information, such as a variogram calculated from well-based lithology information. Additionally, by producing a distribution of models, as opposed to one optimal model, GDM allows for uncertainty quantification. This project aims at assessing the integrated technologies ability to monitor changes in the water table (possibly to one meter resolution) by exploiting the dependence of seismic wave velocities on water saturation of the subsurface. This project, which was funded in part by the National Science Foundation, is a part of the PoroTomo project, funded by a grant from the U.S. Department of Energy.

SERA -- An advanced treatment planning system for neutron therapy and BNCT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nigg, D.W.; Wemple, C.A.; Wessol, D.E.

1999-09-01

Detailed treatment planning calculations on a patient-specific basis are required for boron neutron capture therapy (BNCT). Two integrated treatment planning systems developed specifically for BNCT have been in clinical use in the United States over the past few years. The MacNCTPLAN BNCT treatment planning system is used in the clinical BNCT trials that are underway at the Massachusetts Institute of Technology. A second system, BNCT{_}rtpe (BNCT radiation therapy planning environment), developed independently by the Idaho national Engineering and Environmental Laboratory (INEEL) in collaboration with Montana State University (MSU), is used for treatment planning in the current series of BNCT clinicalmore » trials for glioblastoma at Brookhaven National Laboratory (BNL). This latter system is also licensed for use at several other BNCT research facilities worldwide. Although the currently available BNCT planning systems have served their purpose well, they suffer from somewhat long computation times (2 to 3 CPU-hours or more per field) relative to standard photon therapy planning software. This is largely due to the need for explicit three-dimensional solutions to the relevant transport equations. The simplifying approximations that work well for photon transport computations are not generally applicable to neutron transport computations. Greater computational speeds for BNCT treatment planning must therefore generally be achieved through the application of improved numerical techniques rather than by simplification of the governing equations. Recent efforts at INEEL and MSU have been directed toward this goal. This has resulted in a new paradigm for this type of calculation and the subsequent creation of the new simulation environment for radiotherapy applications (SERA) treatment planning system for BNCT. SERA is currently in initial clinical testing in connection with the trials at BNL, and it is expected to replace the present BNCT{_}rtpe system upon general release during 1999.« less

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP ENTITLED - DOMAIN WALL FERMIONS AT TEN YEARS (VOLUME 84)

DOE Office of Scientific and Technical Information (OSTI.GOV)

BLUM,T.; SONI,A.

The workshop was held to mark the 10th anniversary of the first numerical simulations of QCD using domain wall fermions initiated at BNL. It is very gratifying that in the intervening decade widespread use of domain wall and overlap fermions is being made. It therefore seemed appropriate at this stage for some ''communal introspection'' of the progress that has been made, hurdles that need to be overcome, and physics that can and should be done with chiral fermions. The meeting was very well attended, drawing about 60 registered participants primarily from Europe, Japan and the US. It was quite remarkablemore » that pioneers David Kaplan, Herbert Neuberger, Rajamani Narayanan, Yigal Shamir, Sinya Aoki, and Pavlos Vranas all attended the workshop. Comparisons between domain wall and overlap formulations, with their respective advantages and limitations, were discussed at length, and a broad physics program including pion and kaon physics, the epsilon regime, nucleon structure, and topology, among others, emerged. New machines and improved algorithms have played a key role in realizing realistic dynamical fermion lattice simulations (small quark mass, large volume, and so on), so much in fact that measurements are now as costly. Consequently, ways to make the measurements more efficient were also discussed. We were very pleased to see the keen and ever growing interest in chiral fermions in our community and the significant strides our colleagues have made in bringing chiral fermions to the fore of lattice QCD calculations. Their contributions made the workshop a success, and we thank them deeply for sharing their time and ideas. Finally, we must especially acknowledge Norman Christ and Bob Mawhinney for their early and continued collaboration without which the success of domain wall fermions would not have been possible.« less

Finite element analyses for seismic shear wall international standard problem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Y.J.; Hofmayer, C.H.

Two identical reinforced concrete (RC) shear walls, which consist of web, flanges and massive top and bottom slabs, were tested up to ultimate failure under earthquake motions at the Nuclear Power Engineering Corporation`s (NUPEC) Tadotsu Engineering Laboratory, Japan. NUPEC provided the dynamic test results to the OECD (Organization for Economic Cooperation and Development), Nuclear Energy Agency (NEA) for use as an International Standard Problem (ISP). The shear walls were intended to be part of a typical reactor building. One of the major objectives of the Seismic Shear Wall ISP (SSWISP) was to evaluate various seismic analysis methods for concrete structuresmore » used for design and seismic margin assessment. It also offered a unique opportunity to assess the state-of-the-art in nonlinear dynamic analysis of reinforced concrete shear wall structures under severe earthquake loadings. As a participant of the SSWISP workshops, Brookhaven National Laboratory (BNL) performed finite element analyses under the sponsorship of the U.S. Nuclear Regulatory Commission (USNRC). Three types of analysis were performed, i.e., monotonic static (push-over), cyclic static and dynamic analyses. Additional monotonic static analyses were performed by two consultants, F. Vecchio of the University of Toronto (UT) and F. Filippou of the University of California at Berkeley (UCB). The analysis results by BNL and the consultants were presented during the second workshop in Yokohama, Japan in 1996. A total of 55 analyses were presented during the workshop by 30 participants from 11 different countries. The major findings on the presented analysis methods, as well as engineering insights regarding the applicability and reliability of the FEM codes are described in detail in this report. 16 refs., 60 figs., 16 tabs.« less

Establishment of a Photon Data Section of the BNL National Nuclear Data Center: A preliminary proposal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanson, A.L.; Pearlstein, S.

1992-05-01

It is proposed to establish a Photon Data Section (PDS) of the BNL National Nuclear Data Center (NNDC). This would be a total program encompassing both photon-atom and photon-nucleus interactions. By utilizing the existing NNDC data base management expertise and on-line access capabilities, the implementation of photon interaction data activities within the existing NNDC nuclear structure and nuclear-reaction activities can reestablish a viable photon interaction data program at minimum cost. By taking advantage of the on-line capabilities, the x-ray users' community will have access to a dynamic, state-of-the-art data base of interaction information. The proposed information base would include datamore » that presently are scattered throughout the literature usually in tabulated form. It is expected that the data bases would include at least the most precise data available in photoelectric cross sections, atomic form factors and incoherent scattering functions, anomalous scattering factors, oscillator strengths and oscillator densities, fluorescence yields, Auger electron yields, etc. It could also include information not presently available in tabulations or in existing data bases such as EXAFS (extended x-ray absorption fine structure) reference spectra, chemical bonding induced shifts in the photoelectric absorption edge, matrix corrections, x-ray Raman, and x-ray resonant Raman cross sections. The data base will also include the best estimates of the accuracy of the interaction data as it exists in the data base. It is proposed that the PDS would support computer programs written for calculating scattering cross sections for given solid angles, sample geometries, and polarization of incident x-rays, for calculating Compton profiles, and for analyzing data as in EXAFS and x-ray fluorescence.« less

Establishment of a Photon Data Section of the BNL National Nuclear Data Center: A preliminary proposal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanson, A.L.; Pearlstein, S.

1992-05-01

It is proposed to establish a Photon Data Section (PDS) of the BNL National Nuclear Data Center (NNDC). This would be a total program encompassing both photon-atom and photon-nucleus interactions. By utilizing the existing NNDC data base management expertise and on-line access capabilities, the implementation of photon interaction data activities within the existing NNDC nuclear structure and nuclear-reaction activities can reestablish a viable photon interaction data program at minimum cost. By taking advantage of the on-line capabilities, the x-ray users` community will have access to a dynamic, state-of-the-art data base of interaction information. The proposed information base would include datamore » that presently are scattered throughout the literature usually in tabulated form. It is expected that the data bases would include at least the most precise data available in photoelectric cross sections, atomic form factors and incoherent scattering functions, anomalous scattering factors, oscillator strengths and oscillator densities, fluorescence yields, Auger electron yields, etc. It could also include information not presently available in tabulations or in existing data bases such as EXAFS (extended x-ray absorption fine structure) reference spectra, chemical bonding induced shifts in the photoelectric absorption edge, matrix corrections, x-ray Raman, and x-ray resonant Raman cross sections. The data base will also include the best estimates of the accuracy of the interaction data as it exists in the data base. It is proposed that the PDS would support computer programs written for calculating scattering cross sections for given solid angles, sample geometries, and polarization of incident x-rays, for calculating Compton profiles, and for analyzing data as in EXAFS and x-ray fluorescence.« less

An international dosimetry exchange for BNCT part II: computational dosimetry normalizations.

PubMed

Riley, K J; Binns, P J; Harling, O K; Albritton, J R; Kiger, W S; Rezaei, A; Sköld, K; Seppälä, T; Savolainen, S; Auterinen, I; Marek, M; Viererbl, L; Nievaart, V A; Moss, R L

2008-12-01

The meaningful sharing and combining of clinical results from different centers in the world performing boron neutron capture therapy (BNCT) requires improved precision in dose specification between programs. To this end absorbed dose normalizations were performed for the European clinical centers at the Joint Research Centre of the European Commission, Petten (The Netherlands), Nuclear Research Institute, Rez (Czech Republic), VTT, Espoo (Finland), and Studsvik, Nyköping (Sweden). Each European group prepared a treatment plan calculation that was bench-marked against Massachusetts Institute of Technology (MIT) dosimetry performed in a large, water-filled phantom to uniformly evaluate dose specifications with an estimated precision of +/-2%-3%. These normalizations were compared with those derived from an earlier exchange between Brookhaven National Laboratory (BNL) and MIT in the USA. Neglecting the uncertainties related to biological weighting factors, large variations between calculated and measured dose are apparent that depend upon the 10B uptake in tissue. Assuming a boron concentration of 15 microg g(-1) in normal tissue, differences in the evaluated maximum dose to brain for the same nominal specification of 10 Gy(w) at the different facilities range between 7.6 and 13.2 Gy(w) in the trials using boronophenylalanine (BPA) as the boron delivery compound and between 8.9 and 11.1 Gy(w) in the two boron sulfhydryl (BSH) studies. Most notably, the value for the same specified dose of 10 Gy(w) determined at the different participating centers using BPA is significantly higher than at BNL by 32% (MIT), 43% (VTT), 49% (JRC), and 74% (Studsvik). Conversion of dose specification is now possible between all active participants and should be incorporated into future multi-center patient analyses.

Occupational dose reduction at Department of Energy contractor facilities: Bibliography of selected readings in radiation protection and ALARA; Volume 5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dionne, B.J.; Sullivan, S.G.; Baum, J.W.

1994-01-01

Promoting the exchange of information related to implementation of the As Low as Reasonably Achievable (ALARA) philosophy is a continuing objective for the Department of Energy (DOE). This report was prepared by the Brookhaven National Laboratory (BNL) ALARA Center for the DOE Office of Health. It contains the fifth in a series of bibliographies on dose reduction at DOE facilities. The BNL ALARA Center was originally established in 1983 under the sponsorship of the Nuclear Regulatory Commission to monitor dose-reduction research and ALARA activities at nuclear power plants. This effort was expanded in 1988 by the DOE`s Office of Environment,more » Safety and Health, to include DOE nuclear facilities. This bibliography contains abstracts relating to various aspects of ALARA program implementation and dose-reduction activities, with a specific focus on DOE facilities. Abstracts included in this bibliography were selected from proceedings of technical meetings, journals, research reports, searches of the DOE Energy, Science and Technology Database (in general, the citation and abstract information is presented as obtained from this database), and reprints of published articles provided by the authors. Facility types and activities covered in the scope of this report include: radioactive waste, uranium enrichment, fuel fabrication, spent fuel storage and reprocessing, facility decommissioning, hot laboratories, tritium production, research, test and production reactors, weapons fabrication and testing, fusion, uranium and plutonium processing, radiography, and accelerators. Information on improved shielding design, decontamination, containments, robotics, source prevention and control, job planning, improved operational and design techniques, as well as on other topics, has been included. In addition, DOE/EH reports not included in previous volumes of the bibliography are in this volume (abstracts 611 to 684). This volume (Volume 5 of the series) contains 217 abstracts.« less

Mutagenic interactions between X-rays and two promutagens, o-phenylenediamine and N-nitrosodimethylamine, in the stamen hairs of Tradescantia clone BNL 4430.

PubMed

Xiao, L Z; Ichikawa, S

1998-03-16

Mutagenic interactions between X-rays and two promutagens, o-phenylenediamine (PDA) and N-nitrosodimethylamine (DMN), were studied in the stamen hairs of Tradescantia clone BNL 4430, a blue/pink heterozygote. The young inflorescence-bearing shoots with roots of this clone cultivated in a nutrient solution circulating growth chamber were used as tester plants. After determining dose-response curves for X-rays. PDA and DMN, combined treatments with PDA or DMN and X-rays were conducted, exposing acutely to X-rays 20 h before starting, at the midpoint of, or 20 h after completing the PDA or DMN treatments for 4 h. Clear synergistic effects in inducing somatic pink mutations were detected when X-rays were irradiated before the PDA or DMN treatments, resembling those confirmed earlier between maleic hydrazide (MH) and X-rays. On the contrary, clear antagonistic effects were observed when X-rays were given after the PDA or DMN treatments, also resembling those between MH and X-rays. When X-rayed at the midpoint of the PDA or DMN treatments, merely additive and synergistic effects were observed, respectively, differing from the antagonistic effects between MH and X-rays. The mutagenic synergisms detected were considered to be the results of interactions between DNA strand breaks (and the resultant chromosome breaks) induced by X-rays and those by PDA or DMN, whereas the mutagenic antagonisms observed were presumed to be due to X-ray-caused inhibition of the activation of PDA and DMN in the stamen-hair cells. The time periods required for penetrations into floral tissues and/or activations into mutagens seem different among PDA, DMN and MH. Copyright 1998 Elsevier Science B.V.

Alveolar Macrophages Drive Hepatocellular Carcinoma Lung Metastasis by Generating Leukotriene B4.

PubMed

Nosaka, Takuto; Baba, Tomohisa; Tanabe, Yamato; Sasaki, Soichiro; Nishimura, Tatsunori; Imamura, Yoshiaki; Yurino, Hideaki; Hashimoto, Shinichi; Arita, Makoto; Nakamoto, Yasunari; Mukaida, Naofumi

2018-03-01

Macrophages in lungs can be classified into two subpopulations, alveolar macrophages (AMs) and interstitial macrophages (IMs), which reside in the alveolar and interstitial spaces, respectively. Accumulating evidence indicates the involvement of IMs in lung metastasis, but the roles of AMs in lung metastasis still remain elusive. An i.v. injection of a mouse hepatocellular carcinoma (HCC) cell line, BNL, caused lung metastasis foci with infiltration of AMs and IMs. Comprehensive determination of arachidonic acid metabolite levels revealed increases in leukotrienes and PGs in lungs in this metastasis model. A 5-lipoxygenase (LOX) inhibitor but not a cyclooxygenase inhibitor reduced the numbers of metastatic foci, particularly those of a larger size. A major 5-LOX metabolite, LTB 4 , augmented in vitro cell proliferation of human HCC cell lines as well as BNL cells. Moreover, in this lung metastasis course, AMs exhibited higher expression levels of the 5-LOX and LTB 4 than IMs. Consistently, 5-LOX-expressing AMs increased in the lungs of human HCC patients with lung metastasis, compared with those without lung metastasis. Furthermore, intratracheal clodronate liposome injection selectively depleted AMs but not IMs, together with reduced LTB 4 content and metastatic foci numbers in this lung metastasis process. Finally, IMs in mouse metastatic foci produced CCL2, thereby recruiting blood-borne, CCR2-expressing AMs into lungs. Thus, AMs can be recruited under the guidance of IM-derived CCL2 into metastatic lungs and can eventually contribute to the progression of lung metastasis by providing a potent arachidonic acid-derived tumor growth promoting mediator, LTB 4 . Copyright © 2018 by The American Association of Immunologists, Inc.

Transformation of liver cells by 3-methylcholanthrene potentiates oxidative stress via the downregulation of glutathione synthesis.

PubMed

Kim, Sou Hyun; Yoon, Dahye; Lee, Yun-Hee; Lee, Jaewon; Kim, Nam Deuk; Kim, Suhkmann; Jung, Young-Suk

2017-12-01

Polycyclic aromatic hydrocarbons (PAHs) are widespread contaminants resulting from the incomplete combustion of organic materials in the environment. The primary concern for the hazardous effect of PAHs is their ability to activate the pathway linked to the aryl hydrocarbon receptor (AhR) and lead to carcinogenesis. While previous research has demonstrated that oxidative stress plays a key role in the AhR-dependent toxic response, the effect of PAHs on the biosynthesis of glutathione (GSH), which is a powerful endogenous antioxidant, has not been extensively investigated. In the present study, we utilized a global metabolomic approach, via high resolution magic angle spinning nuclear magnetic resonance spectroscopy, and identified significant metabolome differences between non-tumorigenic liver cells (BNL CL.2; CL2) and transformed liver cells (BNL 1MEA. 7R.1; 1MEA) chronically exposed to 3-methylcholanthrene (3MC), a well‑known carcinogenic PAH. A significant change that was observed, was a lower GSH level in 1MEA cells compared with that in CL2 cells. This was contrasted by increased levels of precursor metabolites for GSH synthesis, such as S-adenosylmethionine and cysteine. These changes were accompanied by a significantly reduced expression of γ-glutamylcysteine ligase (GCL), known to be the rate‑limiting step of GSH synthesis. Furthermore, the protein level of cysteine dioxygenase was downregulated; however, the concentration of taurine was unaltered. Therefore, the present study demonstrated that cells transformed by chronic exposure to 3MC exhibited inhibition of GSH biosynthesis by suppression of GCL protein expression and reduction of cysteine availability, which may subsequently render cells vulnerable to oxidative stress.

Nonlinear guiding of picosecond CO2 laser pulses in atmosphere(Conference Presentation)

NASA Astrophysics Data System (ADS)

Tochitsky, Sergei

2017-05-01

During the last 20 years much attention has been given to the study of propagation of short intense laser pulses for which the peak power exceeds the critical power of self-focusing, Pcr. For a laser power P < Pcr, a dynamic equilibrium between the Kerr self-focusing, diffraction and defocusing caused by laser-ionized plasma result in the production of a high intensity laser filament in air within which a variety of nonlinear optical phenomena are observed. However, research in the 0.8-1 μm range so far has shown a fundamental limitation of guided energy to a few mJ transported within an 100 μm single channel. A long-wavelength, 0 10 μm CO2 laser is a promising candidate for nonlinear guiding because expected high Pcr values according to the modeling should allow for the increase of energy (and therefore power) in a self-guided beam from mJ (GW) to few Joules (TW). During the last decade a significant progress has been achieved in amplification of picosecond pulses to terawatt and recently to <10 TW power level at UCLA and ATF BNL. Such powerful 10 μm lasers open possibility for nonlinear propagation studies in an atmospheric window with high transmission. As a natural first step in a our program on picosecond CO2 laser filamentation, we have made first measurements of Kerr coefficients of air and air constituents around 10 μm. We also undertook direct measurements of n2 of air by analyzing nonlinear self-focusing in air using a 3 ps, 600 GW pulses of the BNL CO2 laser.

Analyses of spontaneous pink mutant events in the stamen hairs of Tradescantia clone BNL 4430 cultivated in a nutrient solution circulating growth chamber.

PubMed

Ichikawa, S; Wushur, S

2000-12-20

In order to obtain more fundamental data on Tradescantia clone BNL 4430, one of the most suitable testers for environmental mutagens, the occurrences of spontaneous somatic pink mutations in the stamen hairs were scored for 52 weeks from 12 December 1998 to 10 December 1999, cultivating the young inflorescence-bearing shoots with roots in a nutrient solution circulating (NSC) growth chamber. The environmental conditions in the chamber were 22.0+/-0.5 degrees C during the 16h day with the light intensity of 7.5klx from white fluorescent tubes, and 20.0+/-0.5 degrees C at night. During the scoring period, 697,443 stamen hairs with an average cell number of 25.36 were observed and 2642 pink mutant events (PMEs) were detected. The overall spontaneous mutation frequency was 1.56+/-0.03 PMEs per 10(4) hair-cell divisions, and the frequency was significantly lower in May, July and August and significantly higher in November and December. By analyzing the sectoring patterns of 1856 PMEs (70.25% of PMEs detected), the most of 172 cases of multiple (two to five) pink sectors observed in the same hairs (scored as 232 PMEs for calculating mutation frequency) were found to be the results of events involving somatic recombinations occurred in single cells or cell lineages, rather than those of two or more independent somatic mutations occurred in different cells. This finding clearly shows the significance of somatic recombinations in producing such multiple sectors (382 sectors in total) which occupied 19.0% of the 2006 pink sectors in total analyzed. Somatic recombinations were considered to be playing a significant role also in producing single PMEs in the stamen hairs.

Anisotropic flow of thermal photons at energies available at the BNL Relativistic Heavy Ion Collider and at the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

Chatterjee, Rupa; Dasgupta, Pingal; Srivastava, Dinesh K.

2017-07-01

We calculate elliptic and triangular flow parameters of thermal photons using an event-by-event hydrodynamic model with fluctuating initial conditions at 200 A GeV Au+Au collisions at the BNL Relativistic Heavy Ion Collider (RHIC) and at 2.76 A TeV Pb+Pb collisions at the Cern Large Hadron Collider (LHC) for three different centrality bins. The photon elliptic flow shows strong centrality dependence where v2(pT) increases towards peripheral collisions both at RHIC and at the LHC energies. However, the triangular flow parameter does not show significant dependence on the collision centrality. The elliptic as well as the triangular flow parameters found to underestimate the PHENIX data at RHIC by a large margin for all three centrality bins. We calculate pT spectrum and anisotropic flow of thermal photons from 200 A GeV Cu+Cu collisions at RHIC for a 0-20% centrality bin and compare with the results with those from Au+Au collisions. The production of thermal photons is found to decrease significantly for Cu+Cu collisions compared to Au+Au collisions. However, the effect of initial state fluctuation is found to be more pronounced for anisotropic flow, resulting in larger v2 and v3 for Cu+Cu collisions. We study the correlation between the anisotropic flow parameters and the corresponding initial spatial anisotropies from their event-by-event distributions at RHIC and at the LHC energies. The linear correlation between v2 and ɛ2 is found be stronger compared to the correlation between v3 and ɛ3. In addition, the correlation coefficient is found to be larger at LHC than at RHIC.

MC and A instrumentation catalog

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neymotin, L.; Sviridova, V.

1998-06-01

In 1981 and 1985, two editions of a catalog of non-destructive nuclear measurement instrumentation, and material control and surveillance equipment, were published by Brookhaven National Laboratory (BNL). The last edition of the catalog included one hundred and twenty-five entries covering a wide range of devices developed in the US and abroad. More than ten years have elapsed since the publication of the more recent Catalog. Devices described in it have undergone significant modifications, and new devices have been developed. Therefore, in order to assist specialists in the field of Material Control and Accounting (MC and A), a new catalog hasmore » been created. Work on this instrumentation catalog started in 1997 as a cooperative effort of Brookhaven National Laboratory (BNL), operated by Brookhaven Science Associates under contract to the US Department of Energy, and the All-Russian Research Institute of Automatics (VNIIA), subordinate institute of the Atomic Energy Ministry of the Russian Federation, within the collaborative US-Russia Material Protection, Control, and Accounting (MPC and A) Program. Most of the equipment included in the Catalog are non-destructive assay (NDA) measurement devices employed for purposes of accounting, confirmation, and verification of nuclear materials. Other devices also included in the Catalog are employed in the detection and deterrence of unauthorized access to or removal of nuclear materials (material control: containment and surveillance). Equipment found in the Catalog comprises either: (1) complete devices or systems that can be used for MC and A applications; or (2) parts or components of complete systems, such as multi-channel analyzers, detectors, neutron generators, and software. All devices are categorized by their status of development--from prototype to serial production.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wessol, D.E.; Wheeler, F.J.; Babcock, R.S.

Several improvements have been developed for the BNCT radiation treatment planning environment (BNCT-Rtpe) during 1994. These improvements have been incorporated into Version 1.0 of BNCT-Rtpe which is currently installed at the INEL, BNL, Japanese Research Center (JRC), and Finland`s Technical Research Center. Platforms supported by this software include Hewlett-Packard (HP), SUN, International Business Machines (IBM), and Silicon Graphics Incorporated (SGI). A draft version of the BNCT-Rtpe user manual is available. Version 1.1 of BNCT-Rtpe is scheduled for release in March 1995. It is anticipated that Version 2.x of BNCT-Rtpe, which includes the nonproprietary NURBS library and data structures, will bemore » released in September 1995.« less

It's No Secret: Fifty-eight Years of National Security Programs at BNL (463rd Brookhaven Lecture)

ScienceCinema

Indusi, Joseph [BNL Nonproliferation and National Security Department

2017-12-09

Prepare for a true tale of suspense and international intrigue. A tale that began in 1952, continued through the Cold War, and is not yet complete today. A tale of unexpected allies. Hear the true tale of one Laboratory’s efforts to keep nuclear materials out of the hands of evildoers. Freidlander. Higinbotham. Dodson. Kouts. And many more! See some of BNL’s all-star cast in the defining roles that shaped their careers as they worked toward keeping the nation and the world safe from the proliferation of nuclear weapons.

Overview of the NASA space radiation laboratory.

PubMed

La Tessa, Chiara; Sivertz, Michael; Chiang, I-Hung; Lowenstein, Derek; Rusek, Adam

2016-11-01

The NASA Space Radiation Laboratory (NSRL) is a multidisciplinary center for space radiation research funded by NASA and located at the Brookhaven National Laboratory (BNL), Upton NY. Operational since 2003, the scope of NSRL is to provide ion beams in support of the NASA Humans in Space program in radiobiology, physics and engineering to measure the risk and ameliorate the effect of radiation in space. Recently, it has also been recognized as the only facility in the U.S. currently capable of contributing to heavy ion radiotherapy research. This work contains a general overview of NSRL structure, capabilities and operation. Copyright © 2016 The Committee on Space Research (COSPAR). All rights reserved.

Energy Dependence of Elliptic Flow over a Large Pseudorapidity Range in Au+Au Collisions at the BNL Relativistic Heavy Ion Collider

NASA Astrophysics Data System (ADS)

Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Hauer, M.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Seals, H.; Sedykh, I.; Skulski, W.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S.; Sukhanov, A.; Tang, J.-L.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Wenger, E.; Wolfs, F. L.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.

2005-04-01

This Letter describes the measurement of the energy dependence of elliptic flow for charged particles in Au+Au collisions using the PHOBOS detector at the Relativistic Heavy Ion Collider. Data taken at collision energies of √(sNN)=19.6, 62.4, 130, and 200 GeV are shown over a wide range in pseudorapidity. These results, when plotted as a function of η'=|η|-ybeam, scale with approximate linearity throughout η', implying no sharp changes in the dynamics of particle production as a function of pseudorapidity or increasing beam energy.

Fermilab muon g-2 experiment

NASA Astrophysics Data System (ADS)

Gorringe, Tim

2018-05-01

The Fermilab muon g-2 experiment will measure the muon anomalous magnetic moment aμ to 140 ppb - a four-fold improvement over the earlier Brookhaven experiment. The measurement of aμ is well known as a unique test of the standard model with broad sensitivity to new interactions, particles and phenomena. The goal of 140 ppb is commensurate with ongoing improvements in the SM prediction of the anomalous moment and addresses the longstanding 3.5σ discrepancy between the BNL result and the SM prediction. In this article I discuss the physics motivation and experimental technique for measuring aμ, and the current status and the future work for the project.

PHENIX Measurements of Heavy Flavor in Small Systems

NASA Astrophysics Data System (ADS)

Lebedev, Alexandre

2018-01-01

The study of heavy flavor production in proton-nucleus and nucleus-nucleus collisions is a sensitive probe of the hot and dense matter created in such collisions. Installation of silicon vertex detectors in the PHENIX experiment, and increased performance of the BNL RHIC collider allowed collection of large amount of data on heavy flavor production in small colliding systems. In this talk we will present recent PHENIX results on open heavy flavor and quarkonia production in p+p, p+A, d+A, and He3+A colliding systems in a broad rapidity range, and discuss how these measurements help us to better understand all stages of nuclear collisions at high energy.

Energy dependence of elliptic flow over a large pseudorapidity range in Au+Au collisions at the BNL relativistic heavy ion collider.

PubMed

Back, B B; Baker, M D; Ballintijn, M; Barton, D S; Betts, R R; Bickley, A A; Bindel, R; Budzanowski, A; Busza, W; Carroll, A; Chai, Z; Decowski, M P; García, E; Gburek, T; George, N; Gulbrandsen, K; Gushue, S; Halliwell, C; Hamblen, J; Hauer, M; Heintzelman, G A; Henderson, C; Hofman, D J; Hollis, R S; Hołyński, R; Holzman, B; Iordanova, A; Johnson, E; Kane, J L; Katzy, J; Khan, N; Kucewicz, W; Kulinich, P; Kuo, C M; Lin, W T; Manly, S; McLeod, D; Mignerey, A C; Nouicer, R; Olszewski, A; Pak, R; Park, I C; Pernegger, H; Reed, C; Remsberg, L P; Reuter, M; Roland, C; Roland, G; Rosenberg, L; Sagerer, J; Sarin, P; Sawicki, P; Seals, H; Sedykh, I; Skulski, W; Smith, C E; Stankiewicz, M A; Steinberg, P; Stephans, G S F; Sukhanov, A; Tang, J-L; Tonjes, M B; Trzupek, A; Vale, C; van Nieuwenhuizen, G J; Vaurynovich, S S; Verdier, R; Veres, G I; Wenger, E; Wolfs, F L H; Wosiek, B; Woźniak, K; Wuosmaa, A H; Wysłouch, B

2005-04-01

This Letter describes the measurement of the energy dependence of elliptic flow for charged particles in Au+Au collisions using the PHOBOS detector at the Relativistic Heavy Ion Collider. Data taken at collision energies of square root of s(NN)=19.6, 62.4, 130, and 200 GeV are shown over a wide range in pseudorapidity. These results, when plotted as a function of eta(')=|eta|-y(beam), scale with approximate linearity throughout eta('), implying no sharp changes in the dynamics of particle production as a function of pseudorapidity or increasing beam energy.

Long-term Energy and Emissions Savings Potential in New York City Buildings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhatt, Vatsal; Lee, John; Klein, Yehuda

2012-09-30

The New York State Energy Research and Development Authority (NYSERDA) partnered with the Brookhaven National Laboratory (BNL) and the City University of New York (CUNY) to develop an integrated methodology that is capable of quantifying the impact of energy efficiency and load management options in buildings, including CUNY’s campus buildings, housing projects, hospitals, and hotels, while capturing the synergies and offsets in a complex and integrated energy-environmental system. The results of this work serve as a guideline in implementing urban energy efficiency and other forms of urban environmental improvement through cost-effective planning at the institutional and local level.

Enhanced R200 with Frisch-Grid CZT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bolotnikov, A.

2017-12-01

The goal of this project is to demonstrate an engineering prototype of a gamma ray spectrometer that uses Cadmium Zinc Telluride (CZT) in a configuration comprised of an array of position-sensitive virtual Frisch grid (PSVFG) detectors and show its capability to perform functions that would be useful to the IAEA. The detectors should achieve energy resolution of ~2% at 200 keV and <1% at > 662 keV, thereby outperforming all hand-held instruments currently in use other than cryogenically cooled germanium. BNL will make every effort to transfer the technology to an industrial partner so that robust, fieldable instruments can bemore » manufactured.« less

Enhanced R200 with Frisch-Grid CZT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bolotnikov, Aleksey

The goal of this project is to demonstrate an engineering prototype of a gamma ray spectrometer that uses Cadmium Zinc Telluride (CZT) in a configuration comprised of an array of position-sensitive virtual Frisch grid (PSVFG) detectors and show its capability to perform functions that would be useful to the IAEA. The detectors should achieve energy resolution of ~2% at 200 keV and <1% at > 662 keV, thereby outperforming all hand-held instruments currently in use other than cryogenically cooled germanium. BNL will make every effort to transfer the technology to an industrial partner so that robust, fieldable instruments can bemore » manufactured.« less

The New Maia Detector System: Methods For High Definition Trace Element Imaging Of Natural Material

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryan, C. G.; School of Physics, University of Melbourne, Parkville VIC; CODES Centre of Excellence, University of Tasmania, Hobart TAS

2010-04-06

Motivated by the need for megapixel high definition trace element imaging to capture intricate detail in natural material, together with faster acquisition and improved counting statistics in elemental imaging, a large energy-dispersive detector array called Maia has been developed by CSIRO and BNL for SXRF imaging on the XFM beamline at the Australian Synchrotron. A 96 detector prototype demonstrated the capacity of the system for real-time deconvolution of complex spectral data using an embedded implementation of the Dynamic Analysis method and acquiring highly detailed images up to 77 M pixels spanning large areas of complex mineral sample sections.

The New Maia Detector System: Methods For High Definition Trace Element Imaging Of Natural Material

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryan, C.G.; Siddons, D.P.; Kirkham, R.

2010-05-25

Motivated by the need for megapixel high definition trace element imaging to capture intricate detail in natural material, together with faster acquisition and improved counting statistics in elemental imaging, a large energy-dispersive detector array called Maia has been developed by CSIRO and BNL for SXRF imaging on the XFM beamline at the Australian Synchrotron. A 96 detector prototype demonstrated the capacity of the system for real-time deconvolution of complex spectral data using an embedded implementation of the Dynamic Analysis method and acquiring highly detailed images up to 77 M pixels spanning large areas of complex mineral sample sections.

The progress of funnelling gun high voltage condition and beam test

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, E.; Ben-Zvi, I.; Gassner, D. M.

A prototype of a high average current polarized electron funneling gun as an eRHIC injector has been built at BNL. The gun was assembled and tested at Stangenes Incorporated. Two beams were generated from two GaAs photocathodes and combined by a switched combiner field. We observed the combined beams on a YAG crystal and measured the photocurrent by a Faraday cup. The gun has been shipped to Stony Brook University and is being tested there. In this paper we will describe the major components of the gun and recent beam test results. High voltage conditioning is discussed as well.

The Spallation Neutron Source (SNS) project accelerator systems

NASA Astrophysics Data System (ADS)

Holmes, Jeffrey A.; Alonso, Jose R.

1999-06-01

The SNS will be the world's leading accelerator-based neutron-scattering research facility when it begins operation in 2005. By delivering 1-MW of beam power to a heavy-metal target in short (<1 μs) bursts of 1-GeV protons, the SNS will provide intense neutron beams with flux levels at least a factor of five over present spallation sources. A multi-laboratory (LBNL, LANL, BNL, ANL and ORNL) collaboration, led by Oak Ridge National Laboratory, has developed a reference design that addresses the challenging technology issues associated with this project. This paper discusses the requirements, issues, and constraints that led to the present design choices.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wheeler, F.; Wessol, D.; Atkinson, C.

During the past few years, murine and large animal research, as well as human studies have provided data to the point where human clinical trials have been initiated at the BMRR using BPA-F for gliomas and at the Massachusetts Institute of Technology Reactor (MITR) using BPA for melanomas of the extremeties. It is expected that glioma trials using BSH will proceed soon at the Petten High Flux Reactor (HFR) in the Netherlands. The first human glioma epithermal boron neutron capture therapy application was performed at the BMRR in the fall of 1994. This was a collaborative effort by BNL, Bethmore » Israel Manhattan hospital, and INEL. The INEL planning system was chosen to perform dose predictions for this application.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amaro, C.R.

This report describes animal dosimetry studies and phantom measurements. During 1994, 12 dogs were irradiated at BMRR as part of a 4 fraction dose tolerance study. The animals were first infused with BSH and irradiated daily for 4 consecutive days. BNL irradiated 2 beagles as part of their dose tolerance study using BPA fructose. In addition, a dog at WSU was irradiated at BMRR after an infusion of BPA fructose. During 1994, the INEL BNCT dosimetry team measured neutron flux and gamma dose profiles in two phantoms exposed to the epithermal neutron beam at the BMRR. These measurements were performedmore » as a preparatory step to the commencement of human clinical trials in progress at the BMRR.« less

Dealing with doomsday

NASA Astrophysics Data System (ADS)

Crease, Robert P.

2010-04-01

There is a classic episode of the US political-satire TV programme The Daily Show about the Relativistic Heavy Ion Collider (RHIC) at the Brookhaven National Laboratory (BNL) in the US. The show was filmed in June 2000, just as scientists were firing up the collider to smash gold nuclei into each other for the first time. The quest of the machine was to recreate the hot, dense soup of free quarks, antiquarks and gluons - the "quark-gluon plasma" - that had previously only ever existed in the first few microseconds after the Big Bang. What had attracted the attention of the programme-makers, however, was not the science but rumours that RHIC would create a world-destroying black hole.

Characterization of the intrinsic scintillator Cs 2LiCeCl 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

James, R.

2017-10-02

In this work, we report on the scintillation properties of the intrinsic scintillator Cs 2LiCeCl 6 (CLCC), which is potentially useful for dual gamma-ray and neutron detection. CLCC is from the elpasolite family with a cubic structure. We grew the crystals at BNL by the vertical Bridgman growth technique. The luminescence spectrum of CLCC showed a doublet with peak maxima at 384 nm and 402 nm. The light yield of CLCC was approximately 20,000 photons/MeV, and the energy resolution was about 6% for 662-keV gamma radiation. A scintillation decay of ~81% of the total light was observed to be ~more » 90 nanoseconds.« less

Azimuthal anisotropy at the relativistic heavy ion collider: the first and fourth harmonics.

PubMed

Adams, J; Adler, C; Aggarwal, M M; Ahammed, Z; Amonett, J; Anderson, B D; Anderson, M; Arkhipkin, D; Averichev, G S; Badyal, S K; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Bekele, S; Belaga, V V; Bellwied, R; Berger, J; Bezverkhny, B I; Bhardwaj, S; Bhaskar, P; Bhati, A K; Bichsel, H; Billmeier, A; Bland, L C; Blyth, C O; Bonner, B E; Botje, M; Boucham, A; Brandin, A; Bravar, A; Cadman, R V; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Carroll, J; Castillo, J; Castro, M; Cebra, D; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, Y; Chernenko, S P; Cherney, M; Chikanian, A; Choi, B; Christie, W; Coffin, J P; Cormier, T M; Cramer, J G; Crawford, H J; Das, D; Das, S; Derevschikov, A A; Didenko, L; Dietel, T; Dong, W J; Dong, X; Draper, J E; Du, F; Dubey, A K; Dunin, V B; Dunlop, J C; Dutta Majumdar, M R; Eckardt, V; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Fachini, P; Faine, V; Faivre, J; Fatemi, R; Filimonov, K; Filip, P; Finch, E; Fisyak, Y; Flierl, D; Foley, K J; Fu, J; Gagliardi, C A; Gagunashvili, N; Gans, J; Ganti, M S; Gaudichet, L; Germain, M; Geurts, F; Ghazikhanian, V; Ghosh, P; Gonzalez, J E; Grachov, O; Grigoriev, V; Gronstal, S; Grosnick, D; Guedon, M; Guertin, S M; Gupta, A; Gushin, E; Gutierrez, T D; Hallman, T J; Hardtke, D; Harris, J W; Heinz, M; Henry, T W; Heppelmann, S; Herston, T; Hippolyte, B; Hirsch, A; Hjort, E; Hoffmann, G W; Horsley, M; Huang, H Z; Huang, S L; Humanic, T J; Igo, G; Ishihara, A; Jacobs, P; Jacobs, W W; Janik, M; Jiang, H; Johnson, I; Jones, P G; Judd, E G; Kabana, S; Kaneta, M; Kaplan, M; Keane, D; Khodyrev, V Yu; Kiryluk, J; Kisiel, A; Klay, J; Klein, S R; Klyachko, A; Koetke, D D; Kollegger, T; Kopytine, M; Kotchenda, L; Kovalenko, A D; Kramer, M; Kravtsov, P; Kravtsov, V I; Krueger, K; Kuhn, C; Kulikov, A I; Kumar, A; Kunde, G J; Kunz, C L; Kutuev, R Kh; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; Lansdell, C P; Lasiuk, B; Laue, F; Lauret, J; Lebedev, A; Lednický, R; LeVine, M J; Li, C; Li, Q; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, L; Liu, Z; Liu, Q J; Ljubicic, T; Llope, W J; Long, H; Longacre, R S; Lopez-Noriega, M; Love, W A; Ludlam, T; Lynn, D; Ma, J; Ma, Y G; Magestro, D; Mahajan, S; Mangotra, L K; Mahapatra, D P; Majka, R; Manweiler, R; Margetis, S; Markert, C; Martin, L; Marx, J; Matis, H S; Matulenko, Yu A; McShane, T S; Meissner, F; Melnick, Yu; Meschanin, A; Messer, M; Miller, M L; Milosevich, Z; Minaev, N G; Mironov, C; Mishra, D; Mitchell, J; Mohanty, B; Molnar, L; Moore, C F; Mora-Corral, M J; Morozov, D A; Morozov, V; de Moura, M M; Munhoz, M G; Nandi, B K; Nayak, S K; Nayak, T K; Nelson, J M; Nevski, P; Nikitin, V A; Nogach, L V; Norman, B; Nurushev, S B; Odyniec, G; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Paic, G; Pandey, S U; Pal, S K; Panebratsev, Y; Panitkin, S Y; Pavlinov, A I; Pawlak, T; Perevoztchikov, V; Perkins, C; Peryt, W; Petrov, V A; Phatak, S C; Picha, R; Planinic, M; Pluta, J; Porile, N; Porter, J; Poskanzer, A M; Potekhin, M; Potrebenikova, E; Potukuchi, B V K S; Prindle, D; Pruneau, C; Putschke, J; Rai, G; Rakness, G; Raniwala, R; Raniwala, S; Ravel, O; Ray, R L; Razin, S V; Reichhold, D; Reid, J G; Renault, G; Retiere, F; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevski, O V; Romero, J L; Rose, A; Roy, C; Ruan, L J; Sahoo, R; Sakrejda, I; Salur, S; Sandweiss, J; Savin, I; Schambach, J; Scharenberg, R P; Schmitz, N; Schroeder, L S; Schweda, K; Seger, J; Seliverstov, D; Seyboth, P; Shahaliev, E; Shao, M; Sharma, M; Shestermanov, K E; Shimanskii, S S; Singaraju, R N; Simon, F; Skoro, G; Smirnov, N; Snellings, R; Sood, G; Sorensen, P; Sowinski, J; Spinka, H M; Srivastava, B; Stanislaus, S; Stock, R; Stolpovsky, A; Strikhanov, M; Stringfellow, B; Struck, C; Suaide, A A P; Sugarbaker, E; Suire, C; Sumbera, M; Surrow, B; Symons, T J M; de Toledo, A Szanto; Szarwas, P; Tai, A; Takahashi, J; Tang, A H; Thein, D; Thomas, J H; Tikhomirov, V; Tokarev, M; Tonjes, M B; Trainor, T A; Trentalange, S; Tribble, R E; Trivedi, M D; Trofimov, V; Tsai, O; Ullrich, T; Underwood, D G; Van Buren, G; VanderMolen, A M; Vasiliev, A N; Vasiliev, M; Vigdor, S E; Viyogi, Y P; Voloshin, S A; Waggoner, W; Wang, F; Wang, G; Wang, X L; Wang, Z M; Ward, H; Watson, J W; Wells, R; Westfall, G D; Whitten, C; Wieman, H; Willson, R; Wissink, S W; Witt, R; Wood, J; Wu, J; Xu, N; Xu, Z; Xu, Z Z; Yamamoto, E; Yepes, P; Yurevich, V I; Zanevski, Y V; Zborovský, I; Zhang, H; Zhang, W M; Zhang, Z P; Zołnierczuk, P A; Zoulkarneev, R; Zoulkarneeva, J; Zubarev, A N

2004-02-13

We report the first observations of the first harmonic (directed flow, v(1)) and the fourth harmonic (v(4)), in the azimuthal distribution of particles with respect to the reaction plane in Au+Au collisions at the BNL Relativistic Heavy Ion Collider (RHIC). Both measurements were done taking advantage of the large elliptic flow (v(2)) generated at RHIC. From the correlation of v(2) with v(1) it is determined that v(2) is positive, or in-plane. The integrated v(4) is about a factor of 10 smaller than v(2). For the sixth (v(6)) and eighth (v(8)) harmonics upper limits on the magnitudes are reported.

Transverse momentum and centrality dependence of high-pT nonphotonic electron suppression in Au+Au collisions at sqrt[s NN]=200 GeV.

PubMed

Abelev, B I; Aggarwal, M M; Ahammed, Z; Anderson, B D; Arkhipkin, D; Averichev, G S; Bai, Y; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Baumgart, S; Belaga, V V; Bellingeri-Laurikainen, A; Bellwied, R; Benedosso, F; Betts, R R; Bhardwaj, S; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Blyth, S-L; Bombara, M; Bonner, B E; Botje, M; Bouchet, J; Brandin, A V; Bravar, A; Burton, T P; Bystersky, M; Cadman, R V; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Callner, J; Catu, O; Cebra, D; Chajecki, Z; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, J Y; Cheng, J; Cherney, M; Chikanian, A; Christie, W; Chung, S U; Coffin, J P; Cormier, T M; Cosentino, M R; Cramer, J G; Crawford, H J; Das, D; Dash, S; Daugherity, M; de Moura, M M; Dedovich, T G; Dephillips, M; Derevschikov, A A; Didenko, L; Dietel, T; Djawotho, P; Dogra, S M; Dong, X; Drachenberg, J L; Draper, J E; Du, F; Dunin, V B; Dunlop, J C; Dutta Mazumdar, M R; Eckardt, V; Edwards, W R; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Fachini, P; Fatemi, R; Fedorisin, J; Feng, A; Filip, P; Finch, E; Fine, V; Fisyak, Y; Fu, J; Gagliardi, C A; Gaillard, L; Ganti, M S; Garcia-Solis, E; Ghazikhanian, V; Ghosh, P; Gorbunov, Y G; Gos, H; Grebenyuk, O; Grosnick, D; Guertin, S M; Guimaraes, K S F F; Gupta, N; Haag, B; Hallman, T J; Hamed, A; Harris, J W; He, W; Heinz, M; Henry, T W; Heppelmann, S; Hippolyte, B; Hirsch, A; Hjort, E; Hoffman, A M; Hoffmann, G W; Hofman, D; Hollis, R; Horner, M J; Huang, H Z; Hughes, E W; Humanic, T J; Igo, G; Iordanova, A; Jacobs, P; Jacobs, W W; Jakl, P; Jia, F; Jones, P G; Judd, E G; Kabana, S; Kang, K; Kapitan, J; Kaplan, M; Keane, D; Kechechyan, A; Kettler, D; Khodyrev, V Yu; Kim, B C; Kiryluk, J; Kisiel, A; Kislov, E M; Klein, S R; Knospe, A G; Kocoloski, A; Koetke, D D; Kollegger, T; Kopytine, M; Kotchenda, L; Kouchpil, V; Kowalik, K L; Kravtsov, P; Kravtsov, V I; Krueger, K; Kuhn, C; Kulikov, A I; Kumar, A; Kurnadi, P; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; Lapointe, S; Laue, F; Lauret, J; Lebedev, A; Lednicky, R; Lee, C-H; Lehocka, S; LeVine, M J; Li, C; Li, Q; Li, Y; Lin, G; Lin, X; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, H; Liu, J; Liu, L; Ljubicic, T; Llope, W J; Longacre, R S; Love, W A; Lu, Y; Ludlam, T; Lynn, D; Ma, G L; Ma, J G; Ma, Y G; Magestro, D; Mahapatra, D P; Majka, R; Mangotra, L K; Manweiler, R; Margetis, S; Markert, C; Martin, L; Matis, H S; Matulenko, Yu A; McClain, C J; McShane, T S; Melnick, Yu; Meschanin, A; Millane, J; Miller, M L; Minaev, N G; Mioduszewski, S; Mironov, C; Mischke, A; Mitchell, J; Mohanty, B; Morozov, D A; Munhoz, M G; Nandi, B K; Nattrass, C; Nayak, T K; Nelson, J M; Nepali, N S; Netrakanti, P K; Nogach, L V; Nurushev, S B; Odyniec, G; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Pachr, M; Pal, S K; Panebratsev, Y; Pavlinov, A I; Pawlak, T; Peitzmann, T; Perevoztchikov, V; Perkins, C; Peryt, W; Phatak, S C; Planinic, M; Pluta, J; Poljak, N; Porile, N; Poskanzer, A M; Potekhin, M; Potrebenikova, E; Potukuchi, B V K S; Prindle, D; Pruneau, C; Putschke, J; Qattan, I A; Raniwala, R; Raniwala, S; Ray, R L; Relyea, D; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Rose, A; Roy, C; Ruan, L; Russcher, M J; Sahoo, R; Sakrejda, I; Sakuma, T; Salur, S; Sandweiss, J; Sarsour, M; Sazhin, P S; Schambach, J; Scharenberg, R P; Schmitz, N; Seger, J; Selyuzhenkov, I; Seyboth, P; Shabetai, A; Shahaliev, E; Shao, M; Sharma, M; Shen, W Q; Shimanskiy, S S; Sichtermann, E P; Simon, F; Singaraju, R N; Smirnov, N; Snellings, R; Sorensen, P; Sowinski, J; Speltz, J; Spinka, H M; Srivastava, B; Stadnik, A; Stanislaus, T D S; Staszak, D; Stock, R; Strikhanov, M; Stringfellow, B; Suaide, A A P; Suarez, M C; Subba, N L; Sumbera, M; Sun, X M; Sun, Z; Surrow, B; Symons, T J M; Szanto de Toledo, A; Takahashi, J; Tang, A H; Tarnowsky, T; Thomas, J H; Timmins, A R; Timoshenko, S; Tokarev, M; Trainor, T A; Trentalange, S; Tribble, R E; Tsai, O D; Ulery, J; Ullrich, T; Underwood, D G; Van Buren, G; van der Kolk, N; van Leeuwen, M; Vander Molen, A M; Varma, R; Vasilevski, I M; Vasiliev, A N; Vernet, R; Vigdor, S E; Viyogi, Y P; Vokal, S; Voloshin, S A; Waggoner, W T; Wang, F; Wang, G; Wang, J S; Wang, X L; Wang, Y; Watson, J W; Webb, J C; Westfall, G D; Wetzler, A; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Wu, J; Wu, Y; Xu, N; Xu, Q H; Xu, Z; Yepes, P; Yoo, I-K; Yue, Q; Yurevich, V I; Zhan, W; Zhang, H; Zhang, W M; Zhang, Y; Zhang, Z P; Zhao, Y; Zhong, C; Zhou, J; Zoulkarneev, R; Zoulkarneeva, Y; Zubarev, A N; Zuo, J X

2007-05-11

The STAR collaboration at the BNL Relativistic Heavy-Ion Collider (RHIC) reports measurements of the inclusive yield of nonphotonic electrons, which arise dominantly from semileptonic decays of heavy flavor mesons, over a broad range of transverse momenta (1.2