Sample records for bohrium 274

  1. Road dust and its effect on human health: a literature review

    PubMed Central

    2018-01-01

    The purpose of this study was to determine the effects of road dust on human health. A PubMed search was used to extract references that included the words “road dust” and “health” or “fugitive dust” and “health” in the title or abstract. A total of 46 references were extracted and selected for review after the primary screening of 949 articles. The respiratory system was found to be the most affected system in the human body. Lead, platinum-group elements (platinum, rhodium, and bohrium), aluminum, zinc, vanadium, and polycyclic aromatic hydrocarbons were the components of road dust that were most frequently referenced in the articles reviewed. Road dust was found to have harmful effects on the human body, especially on the respiratory system. To determine the complex mechanism of action of various components of road dust on the human body and the results thereof, the authors recommend a further meta-analysis and extensive risk-assessment research into the health impacts of dust exposure. PMID:29642653

  2. Comparative Effect of an Addition of a Surface Term to Woods-Saxon Potential on Thermodynamics of a Nucleon

    NASA Astrophysics Data System (ADS)

    Lütfüoğlu, B. C.

    2018-01-01

    In this study, we reveal the difference between Woods-Saxon (WS) and Generalized Symmetric Woods-Saxon (GSWS) potentials in order to describe the physical properties of a nucleon, by means of solving Schrödinger equation for the two potentials. The additional term squeezes the WS potential well, which leads an upward shift in the spectrum, resulting in a more realistic picture. The resulting GSWS potential does not merely accommodate extra quasi bound states, but also has modified bound state spectrum. As an application, we apply the formalism to a real problem, an α particle confined in Bohrium-270 nucleus. The thermodynamic functions Helmholtz energy, entropy, internal energy, specific heat of the system are calculated and compared for both wells. The internal energy and the specific heat capacity increase as a result of upward shift in the spectrum. The shift of the Helmholtz free energy is a direct consequence of the shift of the spectrum. The entropy decreases because of a decrement in the number of available states. Supported by the Turkish Science and Research Council (TÜBİTAK) and Akdeniz University

  3. 32 CFR 274.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Definitions. 274.2 Section 274.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  4. 32 CFR 274.10 - Reservations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Reservations. 274.10 Section 274.10 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  5. 32 CFR 274.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Definitions. 274.2 Section 274.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  6. 32 CFR 274.10 - Reservations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Reservations. 274.10 Section 274.10 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  7. 32 CFR 274.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Purpose. 274.1 Section 274.1 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274.1 Purpose...

  8. 32 CFR 274.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Purpose. 274.1 Section 274.1 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274.1 Purpose...

  9. 32 CFR 274.3 - Public notice.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Public notice. 274.3 Section 274.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  10. 32 CFR 274.3 - Public notice.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Public notice. 274.3 Section 274.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  11. 33 CFR 274.2 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Applicability. 274.2 Section 274.2 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.2 Applicability. This regulation...

  12. 33 CFR 274.5 - Certification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Certification. 274.5 Section 274.5 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.5 Certification. Under the...

  13. 7 CFR 274.7 - Coupon management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Coupon management. 274.7 Section 274.7 Agriculture... FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ISSUANCE AND USE OF COUPONS § 274.7 Coupon management. (a) Coupon inventory management. State agencies shall establish coupon inventory management systems which...

  14. 30 CFR 27.4 - Application procedures and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Application procedures and requirements. 27.4 Section 27.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS METHANE-MONITORING SYSTEMS General Provisions § 27.4 Application...

  15. 32 CFR 274.6 - Submission of bids.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Submission of bids. 274.6 Section 274.6 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  16. 32 CFR 274.4 - U.S. guaranty.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false U.S. guaranty. 274.4 Section 274.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  17. 32 CFR 274.7 - Acceptance of bids.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Acceptance of bids. 274.7 Section 274.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  18. 32 CFR 274.4 - U.S. guaranty.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false U.S. guaranty. 274.4 Section 274.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  19. 32 CFR 274.7 - Acceptance of bids.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Acceptance of bids. 274.7 Section 274.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  20. 32 CFR 274.6 - Submission of bids.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Submission of bids. 274.6 Section 274.6 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN AGREEMENTS § 274...

  1. 48 CFR 211.274-6 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract clauses. 211.274-6 Section 211.274-6 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... with 211.274-2(a)(4) for DoD serially managed subassemblies, components, or parts embedded within...

  2. 48 CFR 211.274-6 - Contract clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract clauses. 211.274-6 Section 211.274-6 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... with 211.274-2(a)(4) for DoD serially managed subassemblies, components, or parts embedded within...

  3. 8 CFR 274a.3 - Continuing employment of unauthorized aliens.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Continuing employment of unauthorized aliens. 274a.3 Section 274a.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.3 Continuing employment of...

  4. 8 CFR 274a.3 - Continuing employment of unauthorized aliens.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Continuing employment of unauthorized aliens. 274a.3 Section 274a.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.3 Continuing employment of...

  5. 8 CFR 274a.3 - Continuing employment of unauthorized aliens.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Continuing employment of unauthorized aliens. 274a.3 Section 274a.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.3 Continuing employment of...

  6. 8 CFR 274a.3 - Continuing employment of unauthorized aliens.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Continuing employment of unauthorized aliens. 274a.3 Section 274a.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.3 Continuing employment of...

  7. 8 CFR 274a.3 - Continuing employment of unauthorized aliens.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Continuing employment of unauthorized aliens. 274a.3 Section 274a.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.3 Continuing employment of...

  8. 7 CFR 1822.274 - Loan closing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Loan closing. 1822.274 Section 1822.274 Agriculture..., Procedures, and Authorizations § 1822.274 Loan closing. (a) Applicable instructions. The complete loan docket will be sent to the OGC for loan closing instructions. RHS loans will be closed in accordance with...

  9. 8 CFR 274.1 - Seizure and forfeiture authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Seizure and forfeiture authority. 274.1 Section 274.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS SEIZURE AND FORFEITURE OF CONVEYANCES § 274.1 Seizure and forfeiture authority. Any officer of Customs and Border...

  10. 8 CFR 274a.4 - Good faith defense.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Good faith defense. 274a.4 Section 274a.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.4 Good faith defense. An employer or a recruiter or referrer for a...

  11. 8 CFR 274a.4 - Good faith defense.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Good faith defense. 274a.4 Section 274a.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.4 Good faith defense. An employer or a recruiter or referrer for a...

  12. 8 CFR 274a.4 - Good faith defense.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Good faith defense. 274a.4 Section 274a.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.4 Good faith defense. An employer or a recruiter or referrer for a...

  13. 8 CFR 274a.4 - Good faith defense.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Good faith defense. 274a.4 Section 274a.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.4 Good faith defense. An employer or a recruiter or referrer for a...

  14. 8 CFR 274a.4 - Good faith defense.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Good faith defense. 274a.4 Section 274a.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.4 Good faith defense. An employer or a recruiter or referrer for a...

  15. 17 CFR 274.130 - Form N-Q, quarterly schedule of portfolio holdings of registered management investment company.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of portfolio holdings of registered management investment company. 274.130 Section 274.130 Commodity... INVESTMENT COMPANY ACT OF 1940 Forms for Reports § 274.130 Form N-Q, quarterly schedule of portfolio holdings of registered management investment company. This form shall be used by registered management...

  16. 8 CFR 274a.12 - Classes of aliens authorized to accept employment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Classes of aliens authorized to accept employment. 274a.12 Section 274a.12 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employment Authorization § 274a.12 Classes of aliens authorized to...

  17. 8 CFR 274a.12 - Classes of aliens authorized to accept employment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Classes of aliens authorized to accept employment. 274a.12 Section 274a.12 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employment Authorization § 274a.12 Classes of aliens authorized to...

  18. 8 CFR 274a.12 - Classes of aliens authorized to accept employment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Classes of aliens authorized to accept employment. 274a.12 Section 274a.12 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employment Authorization § 274a.12 Classes of aliens authorized to...

  19. 8 CFR 274a.12 - Classes of aliens authorized to accept employment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Classes of aliens authorized to accept employment. 274a.12 Section 274a.12 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employment Authorization § 274a.12 Classes of aliens authorized to...

  20. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  1. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  2. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  3. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  4. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  5. 26 CFR 1.274-7 - Treatment of certain expenditures with respect to entertainment-type facilities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 3 2014-04-01 2014-04-01 false Treatment of certain expenditures with respect to entertainment-type facilities. 1.274-7 Section 1.274-7 Internal Revenue INTERNAL REVENUE SERVICE... § 1.274-7 Treatment of certain expenditures with respect to entertainment-type facilities. If...

  6. 26 CFR 1.274-10 - Special rules for aircraft used for entertainment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... entertainment. 1.274-10 Section 1.274-10 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... aircraft used for entertainment. (a) Use of an aircraft for entertainment—(1) In general. Section 274(a) disallows a deduction for certain expenses for entertainment, amusement, or recreation activities, or for an...

  7. 26 CFR 1.274-7 - Treatment of certain expenditures with respect to entertainment-type facilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Treatment of certain expenditures with respect to entertainment-type facilities. 1.274-7 Section 1.274-7 Internal Revenue INTERNAL REVENUE SERVICE... § 1.274-7 Treatment of certain expenditures with respect to entertainment-type facilities. If...

  8. 26 CFR 1.274-10 - Special rules for aircraft used for entertainment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... entertainment. 1.274-10 Section 1.274-10 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... aircraft used for entertainment. (a) Use of an aircraft for entertainment—(1) In general. Section 274(a) disallows a deduction for certain expenses for entertainment, amusement, or recreation activities, or for an...

  9. 26 CFR 1.274-7 - Treatment of certain expenditures with respect to entertainment-type facilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 3 2013-04-01 2013-04-01 false Treatment of certain expenditures with respect to entertainment-type facilities. 1.274-7 Section 1.274-7 Internal Revenue INTERNAL REVENUE SERVICE... § 1.274-7 Treatment of certain expenditures with respect to entertainment-type facilities. If...

  10. 26 CFR 1.274-7 - Treatment of certain expenditures with respect to entertainment-type facilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Treatment of certain expenditures with respect to entertainment-type facilities. 1.274-7 Section 1.274-7 Internal Revenue INTERNAL REVENUE SERVICE... § 1.274-7 Treatment of certain expenditures with respect to entertainment-type facilities. If...

  11. 17 CFR 274.0-1 - Availability of forms.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Availability of forms. 274.0-1 Section 274.0-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT OF 1940 § 274.0-1 Availability of forms. (a) This part identifies...

  12. 48 CFR 236.274 - Restriction on acquisition of steel for use in military construction projects.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of steel for use in military construction projects. 236.274 Section 236.274 Federal Acquisition....274 Restriction on acquisition of steel for use in military construction projects. In accordance with..., Division E), do not acquire, or allow a contractor to acquire, steel for any construction project or...

  13. 48 CFR 236.274 - Restriction on acquisition of steel for use in military construction projects.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of steel for use in military construction projects. 236.274 Section 236.274 Federal Acquisition....274 Restriction on acquisition of steel for use in military construction projects. In accordance with..., Division E), do not acquire, or allow a contractor to acquire, steel for any construction project or...

  14. 48 CFR 236.274 - Restriction on acquisition of steel for use in military construction projects.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of steel for use in military construction projects. 236.274 Section 236.274 Federal Acquisition....274 Restriction on acquisition of steel for use in military construction projects. In accordance with..., Division E), do not acquire, or allow a contractor to acquire, steel for any construction project or...

  15. 48 CFR 236.274 - Restriction on acquisition of steel for use in military construction projects.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of steel for use in military construction projects. 236.274 Section 236.274 Federal Acquisition....274 Restriction on acquisition of steel for use in military construction projects. In accordance with..., Division E), do not acquire, or allow a contractor to acquire, steel for any construction project or...

  16. 48 CFR 236.274 - Restriction on acquisition of steel for use in military construction projects.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of steel for use in military construction projects. 236.274 Section 236.274 Federal Acquisition....274 Restriction on acquisition of steel for use in military construction projects. In accordance with..., Division E), do not acquire, or allow a contractor to acquire, steel for any construction project or...

  17. 12 CFR 27.4 - Inquiry/Application Log.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Inquiry/Application Log. 27.4 Section 27.4... SYSTEM § 27.4 Inquiry/Application Log. (a) The Comptroller, among other things, may require a bank to maintain a Fair Housing Inquiry/Application Log (“Log”), based upon, but not limited to, one or more of the...

  18. 12 CFR 27.4 - Inquiry/Application Log.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Inquiry/Application Log. 27.4 Section 27.4... SYSTEM § 27.4 Inquiry/Application Log. (a) The Comptroller, among other things, may require a bank to maintain a Fair Housing Inquiry/Application Log (“Log”), based upon, but not limited to, one or more of the...

  19. 17 CFR 274.201 - Form N-MFP, portfolio holdings of money market funds.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of money market funds. 274.201 Section 274.201 Commodity and Securities Exchanges SECURITIES AND... Statements § 274.201 Form N-MFP, portfolio holdings of money market funds. This form shall be used by registered open-end management investment companies that are regulated as money market funds under § 270.2a-7...

  20. 17 CFR 274.201 - Form N-MFP, portfolio holdings of money market funds.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... of money market funds. 274.201 Section 274.201 Commodity and Securities Exchanges SECURITIES AND... Statements § 274.201 Form N-MFP, portfolio holdings of money market funds. This form shall be used by registered open-end management investment companies that are regulated as money market funds under § 270.2a-7...

  1. Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCullough, Cheryl E.; Song, Shufei; Shin, Michael H.

    Many histone acetyltransferases undergo autoacetylation, either through chemical or enzymatic means, to potentiate enzymatic cognate substrate lysine acetylation, although the mode and molecular role of such autoacetylation is poorly understood. The MYST family of histone acetyltransferases is autoacetylated at an active site lysine residue to facilitate cognate substrate lysine binding and acetylation. Here, we report on a detailed molecular investigation of Lys-274 autoacetylation of the human MYST protein Males Absent on the First (hMOF). A mutational scan of hMOF Lys-274 reveals that all amino acid substitutions of this residue are able to bind cofactor but are significantly destabilized, both inmore » vitro and in cells, and are catalytically inactive for cognate histone H4 peptide lysine acetylation. The x-ray crystal structure of a hMOF K274P mutant suggests that the reduced stability and catalytic activity stems from a disordering of the residue 274-harboring a α2-β7 loop. We also provide structural evidence that a C316S/E350Q mutant, which is defective for cognate substrate lysine acetylation; and biochemical evidence that a K268M mutant, which is defective for Lys-274 chemical acetylation in the context of a K274-peptide, can still undergo quantitative K274 autoacetylation. Together, these studies point to the critical and specific role of hMOF Lys-274 autoacetylation in hMOF stability and cognate substrate acetylation and argues that binding of Ac-CoA to hMOF likely drives Lys-274 autoacetylation for subsequent cognate substrate acetylation.« less

  2. 17 CFR 274.402 - Form ID, uniform application for access codes to file on EDGAR.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... for access codes to file on EDGAR. 274.402 Section 274.402 Commodity and Securities Exchanges... Forms for Electronic Filing § 274.402 Form ID, uniform application for access codes to file on EDGAR..., filing agent or training agent to log on to the EDGAR system, submit filings, and change its CCC. (d...

  3. 17 CFR 274.402 - Form ID, uniform application for access codes to file on EDGAR.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... for access codes to file on EDGAR. 274.402 Section 274.402 Commodity and Securities Exchanges... Forms for Electronic Filing § 274.402 Form ID, uniform application for access codes to file on EDGAR..., filing agent or training agent to log on to the EDGAR system, submit filings, and change its CCC. (d...

  4. 28 CFR 68.55 - Referral of cases arising under sections 274A or 274C to the Attorney General for review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Review by the Attorney General. When a final order of an Administrative Law Judge or the Chief... 274A or 274C to the Attorney General for review. 68.55 Section 68.55 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE...

  5. 17 CFR 274.130 - Form N-Q, quarterly schedule of portfolio holdings of registered management investment company.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Form N-Q, quarterly schedule of portfolio holdings of registered management investment company. 274.130 Section 274.130 Commodity... INVESTMENT COMPANY ACT OF 1940 Forms for Reports § 274.130 Form N-Q, quarterly schedule of portfolio holdings...

  6. 17 CFR 274.130 - Form N-Q, quarterly schedule of portfolio holdings of registered management investment company.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Form N-Q, quarterly schedule of portfolio holdings of registered management investment company. 274.130 Section 274.130 Commodity... INVESTMENT COMPANY ACT OF 1940 Forms for Reports § 274.130 Form N-Q, quarterly schedule of portfolio holdings...

  7. 17 CFR 274.130 - Form N-Q, quarterly schedule of portfolio holdings of registered management investment company.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Form N-Q, quarterly schedule of portfolio holdings of registered management investment company. 274.130 Section 274.130 Commodity... INVESTMENT COMPANY ACT OF 1940 Forms for Reports § 274.130 Form N-Q, quarterly schedule of portfolio holdings...

  8. 17 CFR 274.130 - Form N-Q, quarterly schedule of portfolio holdings of registered management investment company.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form N-Q, quarterly schedule of portfolio holdings of registered management investment company. 274.130 Section 274.130 Commodity... INVESTMENT COMPANY ACT OF 1940 Forms for Reports § 274.130 Form N-Q, quarterly schedule of portfolio holdings...

  9. 26 CFR 1.274-6T - Substantiation with respect to certain types of listed property for taxable years beginning after...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 3 2013-04-01 2013-04-01 false Substantiation with respect to certain types of listed property for taxable years beginning after 1985 (temporary). 1.274-6T Section 1.274-6T Internal... TAXES (CONTINUED) Items Not Deductible § 1.274-6T Substantiation with respect to certain types of listed...

  10. 26 CFR 1.274-6T - Substantiation with respect to certain types of listed property for taxable years beginning after...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 3 2014-04-01 2014-04-01 false Substantiation with respect to certain types of listed property for taxable years beginning after 1985 (temporary). 1.274-6T Section 1.274-6T Internal... TAXES (CONTINUED) Items Not Deductible § 1.274-6T Substantiation with respect to certain types of listed...

  11. 26 CFR 1.274-6T - Substantiation with respect to certain types of listed property for taxable years beginning after...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Substantiation with respect to certain types of listed property for taxable years beginning after 1985 (temporary). 1.274-6T Section 1.274-6T Internal... TAXES (CONTINUED) Items Not Deductible § 1.274-6T Substantiation with respect to certain types of listed...

  12. 26 CFR 1.274-6T - Substantiation with respect to certain types of listed property for taxable years beginning after...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Substantiation with respect to certain types of listed property for taxable years beginning after 1985 (temporary). 1.274-6T Section 1.274-6T Internal... TAXES (CONTINUED) Items Not Deductible § 1.274-6T Substantiation with respect to certain types of listed...

  13. 50 CFR 660.393 - Latitude/longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the 100 fm (183 m) through 150 fm (274 m) depth contours. 660.393 Section 660.393 Wildlife and... Latitude/longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours... section provides coordinates for the 100 fm (183 m) through 150 fm (274 m) depth contours. (a) The 100-fm...

  14. 26 CFR 1.274-6 - Expenditures deductible without regard to trade or business or other income producing activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Expenditures deductible without regard to trade or business or other income producing activity. 1.274-6 Section 1.274-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Not Deductible § 1.274-6 Expenditures...

  15. 50 CFR 660.73 - Latitude/longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the 100 fm (183 m) through 150 fm (274 m) depth contours. 660.73 Section 660.73 Wildlife and Fisheries.../longitude coordinates defining the 100 fm (183 m) through 150 fm (274 m) depth contours. Boundaries for RCAs... provides coordinates for the 100 fm (183 m) through 150 fm (274 m) depth contours. (a) The 100-fm (183-m...

  16. 40 CFR 264.274-264.275 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....274-264.275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment §§ 264.274-264.275 [Reserved] ...

  17. 40 CFR 264.274-264.275 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....274-264.275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment §§ 264.274-264.275 [Reserved] ...

  18. 40 CFR 264.274-264.275 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....274-264.275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment §§ 264.274-264.275 [Reserved] ...

  19. 40 CFR 264.274-264.275 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....274-264.275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment §§ 264.274-264.275 [Reserved] ...

  20. 40 CFR 264.274-264.275 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....274-264.275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment §§ 264.274-264.275 [Reserved] ...

  1. 33 CFR 274.4 - Pesticide management.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Pesticide management. 274.4... DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.4 Pesticide management. (a... control management personnel prior to advertisement of the contract and procurement of services. The...

  2. 7 CFR 274.3 - Retailer management.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Retailer management. 274.3 Section 274.3 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... management. (a) Retailer participation. (1) All authorized retailers must be afforded the opportunity to...

  3. 33 CFR 274.4 - Pesticide management.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Pesticide management. 274.4... DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.4 Pesticide management. (a... control management personnel prior to advertisement of the contract and procurement of services. The...

  4. 7 CFR 274.3 - Retailer management.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Retailer management. 274.3 Section 274.3 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... management. (a) Retailer participation. (1) All authorized retailers must be afforded the opportunity to...

  5. 33 CFR 274.4 - Pesticide management.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Pesticide management. 274.4... DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.4 Pesticide management. (a... control management personnel prior to advertisement of the contract and procurement of services. The...

  6. 30 CFR 27.4 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... Department of Labor, Mine Safety and Health Administration, Approval and Certification Center, 765 Technology... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Application procedures and requirements. 27.4 Section 27.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING...

  7. 32 CFR 274.8 - Bids-revocations-rejections-postponements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Bids-revocations-rejections-postponements. 274.8 Section 274.8 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY...

  8. 32 CFR 274.8 - Bids-revocations-rejections-postponements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Bids-revocations-rejections-postponements. 274.8 Section 274.8 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY...

  9. 8 CFR 274.2 - Delegation of authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Delegation of authority. 274.2 Section 274.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS SEIZURE AND... designees, for purposes of administering seizures and forfeitures made by Border Patrol Officers. [73 FR...

  10. 33 CFR 274.4 - Pesticide management.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pesticide management. 274.4... DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.4 Pesticide management. (a... control management personnel prior to advertisement of the contract and procurement of services. The...

  11. 48 CFR 211.274-6 - Contract clauses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contract clauses. 211.274-6 Section 211.274-6 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... subassemblies, components, or parts embedded within deliverable items. (4) Use the clause with its Alternate I...

  12. 48 CFR 211.274-6 - Contract clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Contract clauses. 211.274-6 Section 211.274-6 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... subassemblies, components, or parts embedded within deliverable items. (4) Use the clause with its Alternate I...

  13. 48 CFR 211.274-3 - Policy for valuation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Policy for valuation. 211.274-3 Section 211.274-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...) The Government's unit acquisition cost of subassemblies, components, and parts embedded in delivered...

  14. 48 CFR 211.274-2 - Policy for item unique identification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Policy for item unique identification. 211.274-2 Section 211.274-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and Maintaining...

  15. 48 CFR 211.274-2 - Policy for unique item identification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Policy for unique item identification. 211.274-2 Section 211.274-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and Maintaining...

  16. 48 CFR 211.274-3 - Policy for valuation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Policy for valuation. 211.274-3 Section 211.274-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... unit acquisition cost of subassemblies, components, and parts embedded in delivered items need not be...

  17. 48 CFR 211.274-2 - Policy for unique item identification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy for unique item identification. 211.274-2 Section 211.274-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and Maintaining...

  18. 48 CFR 211.274-2 - Policy for unique item identification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Policy for unique item identification. 211.274-2 Section 211.274-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and Maintaining...

  19. 48 CFR 211.274-3 - Policy for valuation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Policy for valuation. 211.274-3 Section 211.274-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... unit acquisition cost of subassemblies, components, and parts embedded in delivered items need not be...

  20. 48 CFR 211.274-2 - Policy for unique item identification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Policy for unique item identification. 211.274-2 Section 211.274-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and Maintaining...

  1. 48 CFR 211.274-3 - Policy for valuation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy for valuation. 211.274-3 Section 211.274-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... unit acquisition cost of subassemblies, components, and parts embedded in delivered items need not be...

  2. 48 CFR 211.274-3 - Policy for valuation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Policy for valuation. 211.274-3 Section 211.274-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... unit acquisition cost of subassemblies, components, and parts embedded in delivered items need not be...

  3. 7 CFR 274.4 - Reconciliation and reporting.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Reconciliation and reporting. 274.4 Section 274.4 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... knowledge and belief. (ii) Coupon issuers and bulk storage points shall submit supporting documentation to...

  4. Publications - GMC 274 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    DGGS GMC 274 Publication Details Title: Total organic carbon analysis with leaching factor from for more information. Bibliographic Reference Brown and Ruth Laboratories, Inc., 1996, Total organic Information gmc274.pdf (109.0 K) Keywords Organic Carbon Top of Page Department of Natural Resources, Division

  5. 17 CFR 274.129 - Form N-PX, annual report of proxy voting record of registered management investment company.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... proxy voting record of registered management investment company. 274.129 Section 274.129 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT... registered management investment company. This form shall be used by registered management investment...

  6. 17 CFR 274.11 - Form N-1, registration statement of open-end management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of open-end management investment companies. 274.11 Section 274.11 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT...(b) of the Investment Company Act of 1940 by open-end management investment companies that are...

  7. 7 CFR 274.6 - Replacement issuances and cards to households.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Replacement issuances and cards to households. 274.6 Section 274.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION... Excessive Replacement Card Notice if they have chosen to exercise the option to withhold the replacement...

  8. 32 CFR 274.5 - Notice of intent to bid.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Notice of intent to bid. 274.5 Section 274.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN...

  9. 32 CFR 274.5 - Notice of intent to bid.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Notice of intent to bid. 274.5 Section 274.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED MILITARY EXPORT LOAN...

  10. 8 CFR 274a.8 - Prohibition of indemnity bonds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Prohibition of indemnity bonds. 274a.8 Section 274a.8 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS CONTROL OF... this section shall, after notice and opportunity for an administrative hearing in accordance with...

  11. 26 CFR 1.274-9 - Entertainment provided to specified individuals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 3 2014-04-01 2014-04-01 false Entertainment provided to specified individuals... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Not Deductible § 1.274-9 Entertainment... exceptions to the disallowance of section 274(a) for expenses for entertainment, amusement, or recreation...

  12. 26 CFR 1.274-9 - Entertainment provided to specified individuals.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 3 2013-04-01 2013-04-01 false Entertainment provided to specified individuals... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Not Deductible § 1.274-9 Entertainment... exceptions to the disallowance of section 274(a) for expenses for entertainment, amusement, or recreation...

  13. 7 CFR 274.1 - State agency issuance responsibility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... a retail food store, if the issuance is performed by a bank, credit union or other financial... 274.1 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ISSUANCE AND USE OF COUPONS § 274.1 State...

  14. 48 CFR 211.274-4 - Policy for reporting of Government-furnished property.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Government-furnished property. 211.274-4 Section 211.274-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and.... (b) The following items are not required to be reported: (1) Contractor-acquired property, as defined...

  15. 48 CFR 211.274-4 - Policy for reporting of Government-furnished property.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Government-furnished property. 211.274-4 Section 211.274-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and.... (b) The following items are not required to be reported: (1) Contractor-acquired property, as defined...

  16. 48 CFR 211.274-4 - Policy for reporting of Government-furnished property.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Government-furnished property. 211.274-4 Section 211.274-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Using and.... (b) The following items are not required to be reported: (1) Contractor-acquired property, as defined...

  17. 28 CFR 27.4 - Corrective action and other relief; Director, Office of Attorney Recruitment and Management.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; Director, Office of Attorney Recruitment and Management. 27.4 Section 27.4 Judicial Administration..., Office of Attorney Recruitment and Management. (a) If, in connection with any investigation, the... recommendations for corrective action, to the Director, Office of Attorney Recruitment and Management (the...

  18. 31 CFR 27.4 - Factors to be considered.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Factors to be considered. 27.4... FOR MISUSE OF DEPARTMENT OF THE TREASURY NAMES, SYMBOLS, ETC. § 27.4 Factors to be considered. The assessing official will consider relevant factors when determining whether to assess or impose a civil...

  19. 26 CFR 1.274-2 - Disallowance of deductions for certain expenses for entertainment, amusement, recreation, or travel.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... for entertainment, amusement, recreation, or travel. 1.274-2 Section 1.274-2 Internal Revenue INTERNAL..., or travel. (a) General rules—(1) Entertainment activity. Except as provided in this section, no... facilities, business leagues, trade associations, chambers of commerce, boards of trade, real estate boards...

  20. 32 CFR 274.9 - Delegation of authority to the Secretary of the Treasury.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Delegation of authority to the Secretary of the Treasury. 274.9 Section 274.9 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED...

  1. 32 CFR 274.9 - Delegation of authority to the Secretary of the Treasury.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Delegation of authority to the Secretary of the Treasury. 274.9 Section 274.9 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS REGULATIONS GOVERNING COMPETITIVE BIDDING ON U.S. GOVERNMENT GUARANTEED...

  2. 38 CFR 3.274 - Relationship of net worth to pension entitlement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Relationship of net worth to pension entitlement. 3.274 Section 3.274 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Regulations Applicable to the Improved Pension Program...

  3. 26 CFR 1.274-7 - Treatment of certain expenditures with respect to entertainment-type facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Treatment of certain expenditures with respect to entertainment-type facilities. 1.274-7 Section 1.274-7 Internal Revenue INTERNAL REVENUE SERVICE... Treatment of certain expenditures with respect to entertainment-type facilities. If deductions are...

  4. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by...-0211 Form N-54A 274.53 3235-0237 Form N-54C 274.54 3235-0236 Form N-SAR 274.101 3235-0330 Form N-27E-1...

  5. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by...-0211 Form N-54A 274.53 3235-0237 Form N-54C 274.54 3235-0236 Form N-SAR 274.101 3235-0330 Form N-27E-1...

  6. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by...-0211 Form N-54A 274.53 3235-0237 Form N-54C 274.54 3235-0236 Form N-SAR 274.101 3235-0330 Form N-27E-1...

  7. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by...-0211 Form N-54A 274.53 3235-0237 Form N-54C 274.54 3235-0236 Form N-SAR 274.101 3235-0330 Form N-27E-1...

  8. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by...-0211 Form N-54A 274.53 3235-0237 Form N-54C 274.54 3235-0236 Form N-SAR 274.101 3235-0330 Form N-27E-1...

  9. Competitive Fitness of Influenza B Viruses Possessing E119A and H274Y Neuraminidase Inhibitor Resistance-Associated Substitutions in Ferrets.

    PubMed

    Pascua, Philippe Noriel Q; Marathe, Bindumadhav M; Burnham, Andrew J; Vogel, Peter; Webby, Richard J; Webster, Robert G; Govorkova, Elena A

    2016-01-01

    Neuraminidase (NA) inhibitors (NAIs) are the only antiviral drugs recommended for influenza treatment and prophylaxis. Although NAI-resistant influenza B viruses that could pose a threat to public health have been reported in the field, their fitness is poorly understood. We evaluated in ferrets the pathogenicity and relative fitness of reverse genetics (rg)-generated influenza B/Yamanashi/166/1998-like viruses containing E119A or H274Y NA substitutions (N2 numbering). Ferrets inoculated with NAI-susceptible rg-wild-type (rg-WT) or NAI-resistant (rg-E119A or rg-H274Y) viruses developed mild infections. Growth of rg-E119A virus in the nasal cavities was delayed, but the high titers at 3 days post-inoculation (dpi) were comparable to those of the rg-WT and rg-H274Y viruses (3.6-4.1 log10TCID50/mL). No virus persisted beyond 5 dpi and replication did not extend to the trachea or lungs. Positive virus antigen-staining of the nasal turbinate epithelium was intermittent with the rg-WT and rg-H274Y viruses; whereas antigen-staining for the rg-E119A virus was more diffuse. Virus populations in ferrets coinoculated with NAI-susceptible and -resistant viruses (1:1 mixture) remained heterogeneous at 5 dpi but were predominantly rg-WT (>70%). Although the E119A substitution was associated with delayed replication in ferrets, the H274Y substitution did not measurably affect viral growth properties. These data suggest that rg-H274Y has undiminished fitness in single virus inoculations, but neither rg-E119A nor rg-H274Y gained a fitness advantage over rg-WT in direct competition experiments without antiviral drug pressure. Taken together, our data suggest the following order of relative fitness in a ferret animal model: rg-WT > rg-H274Y > rg-E119A.

  10. Competitive Fitness of Influenza B Viruses Possessing E119A and H274Y Neuraminidase Inhibitor Resistance–Associated Substitutions in Ferrets

    PubMed Central

    Pascua, Philippe Noriel Q.; Marathe, Bindumadhav M.; Burnham, Andrew J.; Vogel, Peter; Webby, Richard J.; Webster, Robert G.; Govorkova, Elena A.

    2016-01-01

    Neuraminidase (NA) inhibitors (NAIs) are the only antiviral drugs recommended for influenza treatment and prophylaxis. Although NAI-resistant influenza B viruses that could pose a threat to public health have been reported in the field, their fitness is poorly understood. We evaluated in ferrets the pathogenicity and relative fitness of reverse genetics (rg)–generated influenza B/Yamanashi/166/1998-like viruses containing E119A or H274Y NA substitutions (N2 numbering). Ferrets inoculated with NAI-susceptible rg–wild-type (rg-WT) or NAI-resistant (rg-E119A or rg-H274Y) viruses developed mild infections. Growth of rg-E119A virus in the nasal cavities was delayed, but the high titers at 3 days post-inoculation (dpi) were comparable to those of the rg-WT and rg-H274Y viruses (3.6–4.1 log10TCID50/mL). No virus persisted beyond 5 dpi and replication did not extend to the trachea or lungs. Positive virus antigen-staining of the nasal turbinate epithelium was intermittent with the rg-WT and rg-H274Y viruses; whereas antigen-staining for the rg-E119A virus was more diffuse. Virus populations in ferrets coinoculated with NAI-susceptible and -resistant viruses (1:1 mixture) remained heterogeneous at 5 dpi but were predominantly rg-WT (>70%). Although the E119A substitution was associated with delayed replication in ferrets, the H274Y substitution did not measurably affect viral growth properties. These data suggest that rg-H274Y has undiminished fitness in single virus inoculations, but neither rg-E119A nor rg-H274Y gained a fitness advantage over rg-WT in direct competition experiments without antiviral drug pressure. Taken together, our data suggest the following order of relative fitness in a ferret animal model: rg-WT > rg-H274Y > rg-E119A. PMID:27466813

  11. 17 CFR 274.11A - Form N-1A, registration statement of open-end management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of open-end management investment companies. 274.11A Section 274.11A Commodity and Securities...(b) of the Investment Company Act of 1940 by open-end management investment companies other than... registration under the Securities Act of 1933 of the securities of all open-end management investment companies...

  12. 17 CFR 274.11b - Form N-3, registration statement of separate accounts organized as management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of separate accounts organized as management investment companies. 274.11b Section 274.11b... accounts organized as management investment companies. Form N-3 shall be used as the registration statement... offer variable annuity contracts to register as management investment companies. This form shall also be...

  13. Draft Genome Sequence of Chryseobacterium sp. JV274 Isolated from Maize Rhizosphere

    PubMed Central

    Vacheron, Jordan; Dubost, Audrey; Chapulliot, David; Prigent-Combaret, Claire

    2017-01-01

    ABSTRACT We report the draft genome sequence of Chryseobacterium sp. JV274. This strain was isolated from the rhizosphere of maize during a greenhouse experiment. JV274 harbors genes involved in flexirubin production (darA and darB genes), bacterial competition (type VI secretion system), and gliding (bacterial motility; type IX secretion system). PMID:28408666

  14. 17 CFR 274.11a-1 - Form N-2, registration statement of closed end management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of closed end management investment companies. 274.11a-1 Section 274.11a-1 Commodity and... management investment companies. This form shall be used as the registration statement to be filed pursuant to section 8(b) of the Investment Company Act of 1940 by closed end management investment companies...

  15. 17 CFR 274.220 - Form N-17f-2, cover page for each certificate of accounting of securities and similar investments...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... each certificate of accounting of securities and similar investments in the custody of a registered management investment company, filed pursuant to rule 17f-2. 274.220 Section 274.220 Commodity and Securities... accounting of securities and similar investments in the custody of a registered management investment company...

  16. Antipeptide antibodies that can distinguish specific subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.)

    NASA Technical Reports Server (NTRS)

    Cai, X.; Henry, R. L.; Takemoto, L. J.; Guikema, J. A.; Wong, P. P.; Spooner, B. S. (Principal Investigator)

    1992-01-01

    The amino acid sequences of the beta and gamma subunit polypeptides of glutamine synthetase from bean (Phaseolus vulgaris L.) root nodules are very similar. However, there are small regions within the sequences that are significantly different between the two polypeptides. The sequences between amino acids 2 and 9 and between 264 and 274 are examples. Three peptides (gamma 2-9, gamma 264-274, and beta 264-274) corresponding to these sequences were synthesized. Antibodies against these peptides were raised in rabbits and purified with corresponding peptide-Sepharose affinity chromatography. Western blot analysis of polyacrylamide gel electrophoresis of bean nodule proteins demonstrated that the anti-beta 264-274 antibodies reacted specifically with the beta polypeptide and the anti-gamma 264-274 and anti-gamma 2-9 antibodies reacted specifically with the gamma polypeptide of the native and denatured glutamine synthetase. These results showed the feasibility of using synthetic peptides in developing antibodies that are capable of distinguishing proteins with similar primary structures.

  17. 17 CFR 274.303 - Form N-27I-2, notice of withdrawal right and statement of charges for variable life insurance...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). [41 FR... withdrawal right and statement of charges for variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). 274.303 Section 274.303 Commodity and Securities Exchanges...

  18. 40 CFR 180.274 - Propanil; tolerances for residues.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.274 Propanil; tolerances for residues. (a) General. Tolerances are established for the combined residues of the...

  19. 27 CFR 46.274 - Penalties for failure to comply.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PRODUCTS AND CIGARETTE PAPERS AND TUBES Floor Stocks Tax on Certain Tobacco Products, Cigarette Papers, and Cigarette Tubes Held for Sale on April 1, 2009 Ttb Authorities § 46.274 Penalties for failure to comply. If...

  20. 27 CFR 46.274 - Penalties for failure to comply.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PRODUCTS AND CIGARETTE PAPERS AND TUBES Floor Stocks Tax on Certain Tobacco Products, Cigarette Papers, and Cigarette Tubes Held for Sale on April 1, 2009 Ttb Authorities § 46.274 Penalties for failure to comply. If...

  1. 27 CFR 46.274 - Penalties for failure to comply.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PRODUCTS AND CIGARETTE PAPERS AND TUBES Floor Stocks Tax on Certain Tobacco Products, Cigarette Papers, and Cigarette Tubes Held for Sale on April 1, 2009 Ttb Authorities § 46.274 Penalties for failure to comply. If...

  2. 76 FR 33378 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... its Fee Schedule and Exchange Rules 99, 274, 279, 501, 507, 510, 640, 722, 985, 1033, 1092, 1001A.... Additionally, the Exchange proposes to amend Rules 99, 274, 279, 501, 507, 510, 640, 722, 985, 1033, 1092...

  3. 5 CFR 330.1106 - Appointment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... receive noncompetitive appointments to the competitive service under the authority of Public Law 105-274... excepted appointments made under section 11203(b) of Public Law 105-33 to competitive service appointments under Public Law 105-274. For employees appointed before October 21, 1998, the conversion will be...

  4. 5 CFR 330.1106 - Appointment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... receive noncompetitive appointments to the competitive service under the authority of Public Law 105-274... excepted appointments made under section 11203(b) of Public Law 105-33 to competitive service appointments under Public Law 105-274. For employees appointed before October 21, 1998, the conversion will be...

  5. 17 CFR 232.201 - Temporary hardship exemption.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... filing, under cover of Form TH (§§ 239.65, 249.447, 269.10 and 274.404 of this chapter), in paper format... paper format exhibit and a Form TH (§§ 239.65, 249.447, 259.604, 269.10, and 274.404 of this chapter...

  6. 78 FR 43002 - Proposed Collection; Comment Request for Revenue Procedure 2004-29

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... comments concerning statistical sampling in Sec. 274 Context. DATES: Written comments should be received on... INFORMATION: Title: Statistical Sampling in Sec. 274 Contest. OMB Number: 1545-1847. Revenue Procedure Number: Revenue Procedure 2004-29. Abstract: Revenue Procedure 2004-29 prescribes the statistical sampling...

  7. 33 CFR 274.6 - Division/district pest control programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...

  8. 33 CFR 274.6 - Division/district pest control programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...

  9. 33 CFR 274.6 - Division/district pest control programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...

  10. 33 CFR 274.6 - Division/district pest control programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...

  11. 7 CFR 274.3 - Retailer management.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ISSUANCE AND USE OF PROGRAM BENEFITS § 274.3 Retailer... participate in the EBT system. An authorized food retailer shall not be required to participate in an EBT...

  12. 50 CFR 622.274 - Pelagic longline closed areas.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES OF THE CARIBBEAN, GULF OF MEXICO, AND SOUTH ATLANTIC Dolphin and Wahoo Fishery Off the Atlantic States § 622.274 Pelagic longline closed areas. (a) If... dolphin or wahoo— (1) In the Northeastern United States closed area from June 1 through June 30 each year...

  13. 50 CFR 622.274 - Pelagic longline closed areas.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES OF THE CARIBBEAN, GULF OF MEXICO, AND SOUTH ATLANTIC Dolphin and Wahoo Fishery Off the Atlantic States § 622.274 Pelagic longline closed areas. (a) If... dolphin or wahoo— (1) In the Northeastern United States closed area from June 1 through June 30 each year...

  14. 27 CFR 25.274 - Bond.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... TREASURY LIQUORS BEER Pilot Brewing Plants § 25.274 Bond. (a) Requirement. Any person requesting authorization to establish a pilot brewing plant under this subpart shall execute and file a brewer's bond, Form 5130.22. A person may not begin operation of a pilot brewing plant until receiving notice from the...

  15. 27 CFR 25.274 - Bond.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TREASURY LIQUORS BEER Pilot Brewing Plants § 25.274 Bond. (a) Requirement. Any person requesting authorization to establish a pilot brewing plant under this subpart shall execute and file a brewer's bond, Form 5130.22. A person may not begin operation of a pilot brewing plant until receiving notice from the...

  16. 33 CFR 274.7 - Authorization of pesticide use.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Authorization of pesticide use... of pesticide use. (a) Programs approved in § 274.6(b) must be those as described on the pesticide label. Pesticide uses which are different from the registered use, require amendment of the label...

  17. 33 CFR 274.7 - Authorization of pesticide use.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Authorization of pesticide use... of pesticide use. (a) Programs approved in § 274.6(b) must be those as described on the pesticide label. Pesticide uses which are different from the registered use, require amendment of the label...

  18. 33 CFR 274.7 - Authorization of pesticide use.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Authorization of pesticide use... of pesticide use. (a) Programs approved in § 274.6(b) must be those as described on the pesticide label. Pesticide uses which are different from the registered use, require amendment of the label...

  19. 33 CFR 274.7 - Authorization of pesticide use.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Authorization of pesticide use... of pesticide use. (a) Programs approved in § 274.6(b) must be those as described on the pesticide label. Pesticide uses which are different from the registered use, require amendment of the label...

  20. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  1. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  2. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  3. 8 CFR 274a.2 - Verification of identity and employment authorization.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... of birth, sex, height, color of eyes, and address; (ii) School identification card with a photograph... REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.2 Verification of identity and... contain a photograph, identifying information shall be included such as: name, date of birth, sex, height...

  4. 8 CFR 274a.2 - Verification of identity and employment authorization.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... of birth, sex, height, color of eyes, and address; (ii) School identification card with a photograph... REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.2 Verification of identity and... contain a photograph, identifying information shall be included such as: name, date of birth, sex, height...

  5. 8 CFR 274a.2 - Verification of identity and employment authorization.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... of birth, sex, height, color of eyes, and address; (ii) School identification card with a photograph... REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.2 Verification of identity and... contain a photograph, identifying information shall be included such as: name, date of birth, sex, height...

  6. 8 CFR 274a.2 - Verification of identity and employment authorization.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of birth, sex, height, color of eyes, and address; (ii) School identification card with a photograph... REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employer Requirements § 274a.2 Verification of identity and... contain a photograph, identifying information shall be included such as: name, date of birth, sex, height...

  7. 40 CFR 61.274 - Initial report.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Benzene Emissions From Benzene Storage Vessels § 61.274 Initial report. (a) The owner or operator of each storage vessel to which... filled) with benzene. [54 FR 38077, Sept. 14, 1989, as amended at 65 FR 78284, Dec. 14, 2000] ...

  8. 40 CFR 61.274 - Initial report.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Benzene Emissions From Benzene Storage Vessels § 61.274 Initial report. (a) The owner or operator of each storage vessel to which... filled) with benzene. [54 FR 38077, Sept. 14, 1989, as amended at 65 FR 78284, Dec. 14, 2000] ...

  9. 40 CFR 61.274 - Initial report.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Benzene Emissions From Benzene Storage Vessels § 61.274 Initial report. (a) The owner or operator of each storage vessel to which... filled) with benzene. [54 FR 38077, Sept. 14, 1989, as amended at 65 FR 78284, Dec. 14, 2000] ...

  10. 40 CFR 61.274 - Initial report.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Benzene Emissions From Benzene Storage Vessels § 61.274 Initial report. (a) The owner or operator of each storage vessel to which... filled) with benzene. [54 FR 38077, Sept. 14, 1989, as amended at 65 FR 78284, Dec. 14, 2000] ...

  11. 40 CFR 61.274 - Initial report.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Benzene Emissions From Benzene Storage Vessels § 61.274 Initial report. (a) The owner or operator of each storage vessel to which... filled) with benzene. [54 FR 38077, Sept. 14, 1989, as amended at 65 FR 78284, Dec. 14, 2000] ...

  12. 2011 Montana Youth Risk Behavior Survey: Alternative Schools

    ERIC Educational Resources Information Center

    Montana Office of Public Instruction, 2011

    2011-01-01

    This report presents the 2011 Montana Youth Risk Behavior alternative school student frequency distributions. These frequency distributions are based upon surveys with 274 alternative school students in Montana during February of 2011. Frequency distributions may not total 274 due to nonresponse and percents may not total 100 percent due to…

  13. Modeling Vessel-Generated Currents and Bed Shear Stresses

    DTIC Science & Technology

    2008-06-01

    Vessel 1, the fraction of the draft applied over PBOW is 0.95. CSTR 1 0.95 For Vessel 1, the fraction of the draft applied over PSTR is 0.95...vessel draft is 0.95. CSTR 2 0.95 For Vessel 2, the ratio of the stern length to the vessel length is 0.95. PROP 2 1 2.74 6 52 5 The propellers...PBOW 1 0.1 PSTR 1 0.1 CBOW 1 0.95 CSTR 1 0.95 PROP 1 2 2.74 6 52.5 SDEF 1 1 0 -3080.0 -1.5 2.9 FDEF 2 1 -6955.0 -1.5 2.9 DRFT 2 2.74 BLEN 2

  14. 7 CFR 2.74 - Director, Climate Change Program Office.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false Director, Climate Change Program Office. 2.74 Section... Director, Climate Change Program Office. (a) Delegations. Pursuant to § 2.29(a)(12), the following delegations of authority are made by the Chief Economist to the Director, Climate Change Program Office: (1...

  15. 7 CFR 274.7 - Benefit redemption by eligible households.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... purchased prior to the time at which an EBT card is presented to authorized retailers or meal services... household, which includes, for certain households, the purchase of prepared meals, and for other households... receipts at the time of transaction in accordance with § 274.8(b)(7). (e) Access to retail stores. (1) The...

  16. 33 CFR 274.7 - Authorization of pesticide use.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.7 Authorization... unexpected outbreak of a pest requires control measures which are not according to the registered use, such... Engineer. An emergency will be deemed to exist when: (1) A pest outbreak has or is about to occur and no...

  17. 26 CFR 1.274-1 - Disallowance of certain entertainment, gift and travel expenses.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Disallowance of certain entertainment, gift and... certain entertainment, gift and travel expenses. Section 274 disallows in whole, or in part, certain expenditures for entertainment, gifts and travel which would otherwise be allowable under Chapter 1 of the Code...

  18. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Pt. 274, App. A... your control, causing accidental poisoning to the public or domestic animals. 3. Smoking is not... protective clothing are rubber aprons, coveralls, chemical splash goggles, safety shoes, and hard hats. A...

  19. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Pt. 274, App. A... your control, causing accidental poisoning to the public or domestic animals. 3. Smoking is not... protective clothing are rubber aprons, coveralls, chemical splash goggles, safety shoes, and hard hats. A...

  20. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Pt. 274, App. A... your control, causing accidental poisoning to the public or domestic animals. 3. Smoking is not... protective clothing are rubber aprons, coveralls, chemical splash goggles, safety shoes, and hard hats. A...

  1. 29 CFR 1952.274 - Completion of developmental steps and certification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Completion of developmental steps and certification. 1952... § 1952.274 Completion of developmental steps and certification. (a) In accordance with § 1952.273(a... established in January 1974. (d) In accordance with 29 CFR 1952.273(g), the following developmental steps have...

  2. 26 CFR 1.274-1 - Disallowance of certain entertainment, gift and travel expenses.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Disallowance of certain entertainment, gift and... Disallowance of certain entertainment, gift and travel expenses. Section 274 disallows in whole, or in part, certain expenditures for entertainment, gifts and travel which would otherwise be allowable under Chapter...

  3. 26 CFR 1.274-1 - Disallowance of certain entertainment, gift and travel expenses.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 3 2014-04-01 2014-04-01 false Disallowance of certain entertainment, gift and... Disallowance of certain entertainment, gift and travel expenses. Section 274 disallows in whole, or in part, certain expenditures for entertainment, gifts and travel which would otherwise be allowable under Chapter...

  4. 26 CFR 1.274-1 - Disallowance of certain entertainment, gift and travel expenses.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 3 2013-04-01 2013-04-01 false Disallowance of certain entertainment, gift and... Disallowance of certain entertainment, gift and travel expenses. Section 274 disallows in whole, or in part, certain expenditures for entertainment, gifts and travel which would otherwise be allowable under Chapter...

  5. 26 CFR 1.274-1 - Disallowance of certain entertainment, gift and travel expenses.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Disallowance of certain entertainment, gift and... Disallowance of certain entertainment, gift and travel expenses. Section 274 disallows in whole, or in part, certain expenditures for entertainment, gifts and travel which would otherwise be allowable under Chapter...

  6. 33 CFR 274.6 - Division/district pest control programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division... from time to time, will be used as guides in selecting the type of chemicals and the method of application in the control of vegetation and pests at civil works projects. (b) Responsibilities and reports...

  7. XTE J1946+274 = GRO J1944+26 Observations with RXTE and BATSE

    NASA Technical Reports Server (NTRS)

    Wilson, Colleen A.; Finger, Mark H.; Scott, D. Matthew

    2000-01-01

    XTE J1946+274 = GRO J1944+26 is a 15.8 second transient X-ray pulsar discovered simultaneously with the Rossi X-ray Timing Explorer (RXTE) and Burst and Transient Source Experiment (BATSE) onboard the Compton Gamma Ray Observatory (CGRO) during an outburst in September 1998. Since its discovery, XTE J1946+274 has undergone 7 regularly spaced outbursts, that were observed with BATSE and the RXTE All-Sky Monitor (ASM). The pulse frequency and pulsed flux measurements with BATSE suggest that XTE J1946+274 is in an about 170 day orbit and is outbursting twice per orbit. The first outburst, which was brighter and longer than subsequent outbursts, was also observed with the RXTE Proportional Counter Array (PCA). We present histories of pulse frequency, pulsed flux, and total flux measured in the 20-50 keV band with BATSE and a history of the 2-10 keV total flux measured with the RXTE ASM. From the first outburst, we present energy and power spectra and pulse profiles from RXTE PCA observations.

  8. Zinc finger protein 274 regulates imprinted expression of transcripts in Prader-Willi syndrome neurons.

    PubMed

    Langouët, Maéva; Glatt-Deeley, Heather R; Chung, Michael S; Dupont-Thibert, Clémence M; Mathieux, Elodie; Banda, Erin C; Stoddard, Christopher E; Crandall, Leann; Lalande, Marc

    2018-02-01

    Prader-Willi syndrome (PWS) is characterized by neonatal hypotonia, developmental delay and hyperphagia/obesity and is caused by the absence of paternal contribution to chromosome 15q11-q13. Using induced pluripotent stem cell (iPSC) models of PWS, we previously discovered an epigenetic complex that is comprised of the zinc-finger protein ZNF274 and the SET domain bifurcated 1 (SETDB1) histone H3 lysine 9 (H3K9) methyltransferase and that silences the maternal alleles at the PWS locus. Here, we have knocked out ZNF274 and rescued the expression of silent maternal alleles in neurons derived from PWS iPSC lines, without affecting DNA methylation at the PWS-Imprinting Center (PWS-IC). This suggests that the ZNF274 complex is a separate imprinting mark that represses maternal PWS gene expression in neurons and is a potential target for future therapeutic applications to rescue the PWS phenotype. © The Author(s) 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. 17 CFR 274.10 - Form N-8A, for notification of registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form N-8A, for notification of... (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT OF 1940 Registration Statements § 274.10 Form N...: For Federal Register citations affecting Form N-8A, see the List of CFR Sections Affected, which...

  10. 17 CFR 274.10 - Form N-8A, for notification of registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-8A, for notification of... (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT OF 1940 Registration Statements § 274.10 Form N...: For Federal Register citations affecting Form N-8A, see the List of CFR Sections Affected, which...

  11. 17 CFR 274.201 - Form N-MFP, portfolio holdings of money market funds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EXCHANGE COMMISSION (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT OF 1940 Forms for Other... registered open-end management investment companies that are regulated as money market funds under § 270.2a-7... GPO Access. Effective Date Note: At 75 FR 10118, Mar. 4, 2010, § 274.201 was added, effective May 5...

  12. 26 CFR 1.274-5T - Substantiation requirements (temporary).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the business use of listed property, such as a computer or automobile, prepared in a computer memory... such person. (iii) Primary use of a facility. Section 274(a) (1)(B) and (2)(C) deny a deduction for any... information as shall tend to establish such primary use. Such records of use shall contain— (A) For each use...

  13. 26 CFR 1.274-5T - Substantiation requirements (temporary).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the business use of listed property, such as a computer or automobile, prepared in a computer memory... such person. (iii) Primary use of a facility. Section 274(a) (1)(B) and (2)(C) deny a deduction for any... information as shall tend to establish such primary use. Such records of use shall contain— (A) For each use...

  14. 26 CFR 1.274-5T - Substantiation requirements (temporary).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the business use of listed property, such as a computer or automobile, prepared in a computer memory... such person. (iii) Primary use of a facility. Section 274(a) (1)(B) and (2)(C) deny a deduction for any... information as shall tend to establish such primary use. Such records of use shall contain— (A) For each use...

  15. 17 CFR 274.404 - Form TH-Notification of reliance on temporary hardship exemption.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form TH-Notification of... Forms for Electronic Filing § 274.404 Form TH—Notification of reliance on temporary hardship exemption. Form TH shall be filed by any electronic filer who submits to the Commission, pursuant to a temporary...

  16. 17 CFR 274.101 - Form N-SAR, semi-annual report of registered investment companies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form N-SAR, semi-annual report... Forms for Reports § 274.101 Form N-SAR, semi-annual report of registered investment companies. This form...: For Federal Register citations affecting Form N-SAR, see the List of CFR Sections Affected, which...

  17. 17 CFR 274.101 - Form N-SAR, semi-annual report of registered investment companies.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Form N-SAR, semi-annual report... Forms for Reports § 274.101 Form N-SAR, semi-annual report of registered investment companies. This form...: For Federal Register citations affecting Form N-SAR, see the List of CFR Sections Affected, which...

  18. 17 CFR 274.101 - Form N-SAR, semi-annual report of registered investment companies.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Form N-SAR, semi-annual report... Forms for Reports § 274.101 Form N-SAR, semi-annual report of registered investment companies. This form...: For Federal Register citations affecting Form N-SAR, see the List of CFR Sections Affected, which...

  19. 17 CFR 274.101 - Form N-SAR, semi-annual report of registered investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-SAR, semi-annual report... Forms for Reports § 274.101 Form N-SAR, semi-annual report of registered investment companies. This form...: For Federal Register citations affecting Form N-SAR, see the List of CFR Sections Affected, which...

  20. 17 CFR 274.101 - Form N-SAR, semi-annual report of registered investment companies.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Form N-SAR, semi-annual report... Forms for Reports § 274.101 Form N-SAR, semi-annual report of registered investment companies. This form...: For Federal Register citations affecting Form N-SAR, see the List of CFR Sections Affected, which...

  1. 77 FR 45698 - Agency Information Collection Activities: Submission for the Office of Management and Budget...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... District of Columbia and the Commonwealth of Puerto Rico that have not signed Section 274(b) Agreements... and as part of the NRC's cooperative post-agreement program with the States pursuant to Section 274(b... information are exchanged. Therefore, information requests sought may take the form of surveys, e.g...

  2. Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.

    PubMed

    Sohn, Peter Dongmin; Tracy, Tara E; Son, Hye-In; Zhou, Yungui; Leite, Renata E P; Miller, Bruce L; Seeley, William W; Grinberg, Lea T; Gan, Li

    2016-06-29

    Neurons are highly polarized cells in which asymmetric axonal-dendritic distribution of proteins is crucial for neuronal function. Loss of polarized distribution of the axonal protein tau is an early sign of Alzheimer's disease (AD) and other neurodegenerative disorders. The cytoskeletal network in the axon initial segment (AIS) forms a barrier between the axon and the somatodentritic compartment, contributing to axonal retention of tau. Although perturbation of the AIS cytoskeleton has been implicated in neurological disorders, the molecular triggers and functional consequence of AIS perturbation are incompletely understood. Here we report that tau acetylation and consequent destabilization of the AIS cytoskeleton promote the somatodendritic mislocalization of tau. AIS cytoskeletal proteins, including ankyrin G and βIV-spectrin, were downregulated in AD brains and negatively correlated with an increase in tau acetylated at K274 and K281. AIS proteins were also diminished in transgenic mice expressing tauK274/281Q, a tau mutant that mimics K274 and K281 acetylation. In primary neuronal cultures, the tauK274/281Q mutant caused hyperdynamic microtubules (MTs) in the AIS, shown by live-imaging of MT mobility and fluorescence recovery after photobleaching. Using photoconvertible tau constructs, we found that axonal tauK274/281Q was missorted into the somatodendritic compartment. Stabilizing MTs with epothilone D to restore the cytoskeletal barrier in the AIS prevented tau mislocalization in primary neuronal cultures. Together, these findings demonstrate that tau acetylation contributes to the pathogenesis of neurodegenerative disease by compromising the cytoskeletal sorting machinery in the AIS.

  3. Cognitive error as the most frequent contributory factor in cases of medical injury: a study on verdict's judgment among closed claims in Japan.

    PubMed

    Tokuda, Yasuharu; Kishida, Naoki; Konishi, Ryota; Koizumi, Shunzo

    2011-03-01

    Cognitive errors in the course of clinical decision-making are prevalent in many cases of medical injury. We used information on verdict's judgment from closed claims files to determine the important cognitive factors associated with cases of medical injury. Data were collected from claims closed between 2001 to 2005 at district courts in Tokyo and Osaka, Japan. In each case, we recorded all the contributory cognitive, systemic, and patient-related factors judged in the verdicts to be causally related to the medical injury. We also analyzed the association between cognitive factors and cases involving paid compensation using a multivariable logistic regression model. Among 274 cases (mean age 49 years old; 45% women), there were 122 (45%) deaths and 67 (24%) major injuries (incomplete recovery within a year). In 103 cases (38%), the verdicts ordered hospitals to pay compensation (median; 8,000,000 Japanese Yen). An error in judgment (199/274, 73%) and failure of vigilance (177/274, 65%) were the most prevalent causative cognitive factors, and error in judgment was also significantly associated with paid compensation (odds ratio, 1.9; 95% confidence interval [CI], 1.0-3.4). Systemic causative factors including poor teamwork (11/274, 4%) and technology failure (5/274, 2%) were less common. The closed claims analysis based on verdict's judgment showed that cognitive errors were common in cases of medical injury, with an error in judgment being most prevalent and closely associated with compensation payment. Reduction of this type of error is required to produce safer healthcare. 2010 Society of Hospital Medicine.

  4. CD274 (PDL1) and JAK2 genomic amplifications in pulmonary squamous-cell and adenocarcinoma patients.

    PubMed

    Clavé, Sergi; Pijuan, Lara; Casadevall, David; Taus, Álvaro; Gimeno, Javier; Hernández-Llodrà, Silvia; Rodríguez-Rivera, María; Lorenzo, Marta; Menéndez, Silvia; Albanell, Joan; Espinet, Blanca; Arriola, Edurne; Salido, Marta

    2018-01-01

    CD274 (PDL1) and JAK2 (9p24.1) gene amplifications have been recently described in pulmonary carcinomas in association with programmed death-ligand 1 (PD-L1) expression. Furthermore, PTEN loss has been explored preclinically in relation to PD-L1 expression. Our aim was to determine whether these genomic alterations affect PD-L1 expression levels in non-small-cell lung cancer. PD-L1 and PTEN expression determined by immunohistochemistry (IHC), and CD274, JAK2 and PTEN copy number alterations (CNAs) determined by fluorescence in-situ hybridisation, were studied in 171 pulmonary carcinoma specimens. PD-L1 expression was positive in 40 cases (23.3%), and CD274 amplification was present in 14 tumours (8.8%). Concordance between both events was found in 12 of 14 amplified cases (P = 0.0001). We found nine JAK2-amplified cases (5.7%), seven with PD-L1 expression (P = 0.0006). Moreover, six of the seven cases had JAK2 and CD274 coamplification (9p24.1 genomic amplification). Remarkably, the average PD-L1 IHC score was higher in these amplified cases (230 versus 80; P = 0.001). Non-statistical associations were observed between PD-L1 expression and PTEN loss and PTEN deletions. We describe a subset of patients (8.2%) who had 9p24.1 amplifications resulting in high expression of PD-L1. Our results provide evidence for genomic up-regulation of PD-L1 expression in non-small-cell lung cancer. © 2017 John Wiley & Sons Ltd.

  5. 28 CFR 68.56 - Judicial review of a final agency order in cases arising under section 274A or 274C.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... review by the Chief Administrative Hearing Officer of a final order by an Administrative Law Judge shall... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Judicial review of a final agency order... OF JUSTICE (CONTINUED) RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE...

  6. 17 CFR 274.219 - Form N-17f-1, cover page for each certificate of accounting of securities and similar investments...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... each certificate of accounting of securities and similar investments of a management investment company... PRESCRIBED UNDER THE INVESTMENT COMPANY ACT OF 1940 Forms for Other Statements § 274.219 Form N-17f-1, cover page for each certificate of accounting of securities and similar investments of a management...

  7. 26 CFR 1.274-6T - Substantiation with respect to certain types of listed property for taxable years beginning after...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... substantiating any working condition fringe exclusion as well as to an employer. For example, if an employee... than the trade or business of being the employee of the employer providing the vehicle. (f) Effective... substantiation requirements under section 274(d). Therefore, the employee need not keep a separate set of records...

  8. 17 CFR 274.203 - Form 4, statement of changes in beneficial ownership of securities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form 4, statement of changes... Forms for Other Statements § 274.203 Form 4, statement of changes in beneficial ownership of securities. This form shall be filed pursuant to § 270.30h-1 for statements of changes in beneficial ownership of...

  9. 17 CFR 274.203 - Form 4, statement of changes in beneficial ownership of securities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form 4, statement of changes... Forms for Other Statements § 274.203 Form 4, statement of changes in beneficial ownership of securities. This form shall be filed pursuant to § 270.30h-1 for statements of changes in beneficial ownership of...

  10. XTE J1946+274: An Enigmatic X-Ray Pulsar

    NASA Technical Reports Server (NTRS)

    Wilson, Colleen A.; Finger, Mark H.; Coe, M. J.; Negueruela, Ignacio; Six, N. Frank (Technical Monitor)

    2002-01-01

    XTE J1946+274 = GRO J1944+26 is a 15.8-s X-ray pulsar discovered simultaneously by the Rossi X-ray Timing Explorer (RXTE) and the Burst and Transient Source Experiment (BATSE) in September 1998. Follow-up optical/IR observations resulted in the discovery of a Be star companion. Our pulse timing analysis of BATSE and RXTE data indicates that the orbital period is approximately 169 days. Since its discovery in 1998, XTE J1946+274 has undergone 13 outbursts. These outbursts axe not regularly spaced. They occur approximately twice per orbit and are not locked in orbital phase, unlike most Be/X-ray transient systems. A possible explanation for this is a global-one armed oscillation or density perturbation propagating rapidly in the Be star's disk. We will investigate radial velocity variations in the central peak of the H-alpha line to look for evidence of such a perturbation. From 2001 March-September, we regularly monitored XTE J1946+274 with the RXTE PCA. We will demonstrate that the spectrum appears to be varying with orbital phase, based on the 2001 and 1998 RXTE PCA observations. We will also present histories of pulsed frequency and flux.

  11. 28 CFR 68.53 - Review of an interlocutory order of an Administrative Law Judge in cases arising under section...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... proceedings. Review of an Administrative Law Judge's interlocutory order will not stay the proceeding unless... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Review of an interlocutory order of an Administrative Law Judge in cases arising under section 274A or 274C. 68.53 Section 68.53 Judicial Administration...

  12. 17 CFR 249.322 - Form 12b-25-Notification of late filing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-annual, annual, or transition report on Form N-SAR (§§ 249.330; 274.101) or Form N-CSR (§§ 249.331; 274... date for the periodic report in question. Copies of this form may be obtained from “Publications....201 or § 232.202 of this chapter), or apply for an adjustment in filing date pursuant to Rule 13(b) of...

  13. 17 CFR 249.322 - Form 12b-25-Notification of late filing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-annual, annual, or transition report on Form N-SAR (§§ 249.330; 274.101) or Form N-CSR (§§ 249.331; 274... date for the periodic report in question. Copies of this form may be obtained from “Publications....201 or § 232.202 of this chapter), or apply for an adjustment in filing date pursuant to Rule 13(b) of...

  14. 17 CFR 249.322 - Form 12b-25-Notification of late filing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-annual, annual, or transition report on Form N-SAR (§§ 249.330; 274.101) or Form N-CSR (§§ 249.331; 274... date for the periodic report in question. Copies of this form may be obtained from “Publications....201 or § 232.202 of this chapter), or apply for an adjustment in filing date pursuant to Rule 13(b) of...

  15. 17 CFR 249.322 - Form 12b-25-Notification of late filing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-annual, annual, or transition report on Form N-SAR (§§ 249.330; 274.101) or Form N-CSR (§§ 249.331; 274... date for the periodic report in question. Copies of this form may be obtained from “Publications....201 or § 232.202 of this chapter), or apply for an adjustment in filing date pursuant to Rule 13(b) of...

  16. 17 CFR 249.322 - Form 12b-25-Notification of late filing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-annual, annual, or transition report on Form N-SAR (§§ 249.330; 274.101) or Form N-CSR (§§ 249.331; 274... date for the periodic report in question. Copies of this form may be obtained from “Publications....201 or § 232.202 of this chapter), or apply for an adjustment in filing date pursuant to Rule 13(b) of...

  17. Protecting America Through Better Civic Education

    DTIC Science & Technology

    2013-09-01

    27 Audiologist 3.99 Elementary—Pre-Kindergarten 2.74 Physical Therapist 3.91 Art/Visual Education 2.74 Languages—Spanish 3.88 Elementary...2009-recruitment-and-radicalization.pdf. 2 Wayne Drash, Boni Masu, and Tom Watkins, 2013, Boston Suspects: Immigrant Dream to American Nightmare, CNN...on our soil. Immigration issues within the U.S, especially at the southern border, must be considered. As we admit more immigrants into the country

  18. 17 CFR 274.302 - Form N-27I-1, notice of right of withdrawal and refund for variable life insurance...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of withdrawal and refund for variable life insurance contractholders required pursuant to Rule 6e-2... for Exemptions § 274.302 Form N-27I-1, notice of right of withdrawal and refund for variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). [41 FR 47032, Oct. 27...

  19. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... and Form N-Q. 270.30a-2 Section 270.30a-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter) or Form N-Q (§§ 249.332 and 274.130 of this chapter) by a registered management investment company...

  20. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... and Form N-Q. 270.30a-2 Section 270.30a-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter) or Form N-Q (§§ 249.332 and 274.130 of this chapter) by a registered management investment company...

  1. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... and Form N-Q. 270.30a-2 Section 270.30a-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter) or Form N-Q (§§ 249.332 and 274.130 of this chapter) by a registered management investment company...

  2. The reawakening of the sleeping X-ray pulsar XTE J1946+274

    NASA Astrophysics Data System (ADS)

    Müller, S.; Kühnel, M.; Caballero, I.; Pottschmidt, K.; Fürst, F.; Kreykenbohm, I.; Sagredo, M.; Obst, M.; Wilms, J.; Ferrigno, C.; Rothschild, R. E.; Staubert, R.

    2012-10-01

    We report on a series of outbursts of the high-mass X-ray binary XTE J1946+274 in 2010/2011 observed with INTEGRAL, RXTE, and Swift. We discuss possible mechanisms resulting in the extraordinary outburst behavior of this source. The X-ray spectra can be described by standard phenomenological models, enhanced by an absorption feature of unknown origin at about 10 keV and a narrow iron Kα fluorescence line at 6.4 keV, which are variable in flux and pulse phase. We find possible evidence for a cyclotron resonance scattering feature at about 25 keV at the 93% level. The presence of a strong cyclotron line at 35 keV seen in data from the source's 1998 outburst that was confirmed by a reanalysis of these data can be excluded. This result indicates that the cyclotron line feature in XTE J1946+274 is variable between individual outbursts.

  3. The Reawakening of the Sleeping X-ray Pulsar XTE J1946+274

    NASA Technical Reports Server (NTRS)

    Mueller, Sebastian; Mueller, Sebastian; Kuechnel, Matthias; Fuerst, Felix; Kreykenbohm, Ingo; Sagredo, Macarena; Obst, Maria; Wilms, Joern; Caballero, Isabel; Potttschmidt, Katja; hide

    2012-01-01

    We report on a series of outbursts of the high mass X-ray binary XTE 11946+274 in 2010/2011 as observed with INTEGRAL, RXTE, and Swift. We discuss possible mechanisms resulting in the extraordinary outburst behavior of this source. The X-ray spectra can be described by standard phenomenological models, enhanced by an absorption feature of unknown origin at about 10 keV and a narrow iron K alpha fluorescence line at 6.4keV, which are variable in flux and pulse phase. We find possible evidence for the presence of a cyclotron resonance scattering feature at about 25 keV at the 93% level. The presence of a strong cyclotron line at 35 keV seen in data from the source's 1998 outburst and confirmed by a reanalysis of these data can be excluded. This result indicates that the cyclotron line feature in XTE 11946+274 is variable between individual outbursts.

  4. Corrective Action Decision Document/Closure Report for Corrective Action Unit 274: Septic Systems, Nevada Test Site, Nevada, Rev. No.: 0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grant Evenson

    2006-09-01

    This Corrective Action Decision Document/Closure Report has been prepared for Corrective Action Unit 274, Septic Systems, Nevada Test Site (NTS), Nevada in accordance with the ''Federal Facility Agreement and Consent Order'' (1996). Corrective Action Unit (CAU) 274 is comprised of five corrective action sites (CASs): (1) CAS 03-02-01, WX-6 ETS Building Septic System; (2) CAS 06-02-01, Cesspool; (3) CAS 09-01-01, Spill Site; (4) CAS 09-05-01, Leaching Pit; and (5) CAS 20-05-01, Septic System. The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the closure of CAU 274 with no further corrective action. Tomore » achieve this, corrective action investigation (CAI) activities were performed from November 14 through December 17, 2005 as set forth in the CAU 274 Corrective Action Investigation Plan. The purpose of the CAI was to fulfill the following data needs as defined during the data quality objective (DQO) process: (1) Determine whether contaminants of concern (COCs) are present. (2) If contaminants of concern are present, determine their nature and extent. (3) Provide sufficient information and data to complete appropriate corrective actions. The CAU 274 dataset from the investigation results was evaluated based on the data quality indicator parameters. This evaluation demonstrated the quality and acceptability of the dataset for use in fulfilling the DQO data needs. Analytes detected during the CAI were evaluated against final action levels (FALs) established in this document. No analytes were detected at concentrations exceeding the FALs. No COCs have been released to the soil at CAU 274, and corrective action is not required. Therefore, the DQO data needs were met, and it was determined that no corrective action based on risk to human receptors is necessary for the site. All FALs were calculated using the industrial site worker scenario except for benzo(a)pyrene, which was calculated based on the occasional use scenario. Benzo(a)pyrene was detected above the preliminary action level at CAS 20-05-01; however, it was not identified as a COC because the concentration was below the FAL. As a best management practice and to ensure that future site workers are not exposed to this site contaminant for more than this decision-basis exposure duration, an administrative use restriction was established around the leachfield at CAS 20-05-01. In addition, the removal of the septic tanks and septic tank contents at CASs 03-02-01, 06-02-01, and 20-05-01 was performed.« less

  5. Theater Missile Defense Extended Test Range Supplemental Environmental Impact Statement - Eglin Gulf Test Range. Volume 1

    DTIC Science & Technology

    1998-07-01

    facilities No existing infrastructure or utilities Yucatan Peninsula, Mexico Not on DOD property Expense due to logistics Matagorda Island... nutritive or harmful substances from the soil by percolation of a liquid Lead—a heavy metal which can accumulate in the body and cause a variety of negative...THE YUCATAN PENINSULA, MEXICO ............ 2-74 2.3.3 LAUNCH FROM MATAGORDA ISLAND, TEXAS ..................... 2-74 2.3.4 LAUNCH FROM BOCA CHICA KEY

  6. Protection of chickens vaccinated with combinations of commercial live infectious bronchitis vaccines containing Massachusetts, Dutch and QX-like serotypes against challenge with virulent infectious bronchitis viruses 793B and IS/1494/06 Israel variant 2.

    PubMed

    Bru, T; Vila, R; Cabana, M; Geerligs, H J

    2017-02-01

    Infectious bronchitis virus (IBV) is a coronavirus which affects chickens of all ages. IBV mainly causes respiratory disease but can also result in reduced weight gain, reduced egg production, increased frequency of abnormal eggs and increased rates of mortality. Vaccination is the most important way to control the disease. Nevertheless, novel strains of infectious bronchitis (IB) continue to emerge in the field. In order to respond promptly, combinations of existing IB vaccines are frequently tested to see whether they can provide cross-protection. The efficacy of a combination of vaccines based on Massachusetts, Dutch and QX-like IB strains against emerging IB Israel variant 2 and IB 793B strains was assessed by means of four challenge studies. At least 80% of the birds vaccinated with IB H120 (Mass type) combined with IB D274 (Dutch type) followed by a QX-like IB vaccine booster or vaccinated with a combination of IB H120, IB D274 and QX-like IB were protected against a challenge with IB 793B. In addition, IB 1263 (Mass type) boosted by QX-like IB showed an 85% protection following challenge with IB 793B. A combination of IB H120 and IB D274 boosted by QX-like IB vaccine conferred 70% protection whilst H120 and IB D274 combination on its own showed 61.1% protection against Israel variant 2 challenge. IB 1263 boosted by a QX-like IB vaccine showed 50% protection against IB Israel variant 2. Therefore, it can be concluded that a combination of the IB H120, IB D274 and QX-like IB confers broad protection against different non-related virulent IB strains.

  7. 300-MHz-repetition-rate, all-fiber, femtosecond laser mode-locked by planar lightwave circuit-based saturable absorber.

    PubMed

    Kim, Chur; Kim, Dohyun; Cheong, YeonJoon; Kwon, Dohyeon; Choi, Sun Young; Jeong, Hwanseong; Cha, Sang Jun; Lee, Jeong-Woo; Yeom, Dong-Il; Rotermund, Fabian; Kim, Jungwon

    2015-10-05

    We show the implementation of fiber-pigtailed, evanescent-field-interacting, single-walled carbon nanotube (CNT)-based saturable absorbers (SAs) using standard planar lightwave circuit (PLC) fabrication processes. The implemented PLC-CNT-SA device is employed to realize self-starting, high-repetition-rate, all-fiber ring oscillators at telecommunication wavelength. We demonstrate all-fiber Er ring lasers operating at 303-MHz (soliton regime) and 274-MHz (stretched-pulse regime) repetition-rates. The 303-MHz (274-MHz) laser centered at 1555 nm (1550 nm) provides 7.5 nm (19 nm) spectral bandwidth. After extra-cavity amplilfication, the amplified pulse train of the 303-MHz (274-MHz) laser delivers 209 fs (178 fs) pulses. To our knowledge, this corresponds to the highest repetition-rates achieved for femtosecond lasers employing evanescent-field-interacting SAs. The demonstrated SA fabrication method, which is based on well-established PLC processes, also shows a potential way for mass-producible and lower-cost waveguide-type SA devices suitable for all-fiber and waveguide lasers.

  8. An Evaluation of the United States Air Force Menu Concerning Kilocalorie, Total Fat, Cholesterol and Sodium.

    DTIC Science & Technology

    1983-05-01

    following changes in food selection * and preparation: - increase consumption of fruits and vegetables and whole grains . - decrease consumption of refined...NONSTANDARD ITEMS VEGETABLE JUICE 45 TRACE -- 887 8 oz. HALF GRAPEFRUIT 95 TRACE -- 1 BACON 85 8 70 274 2 slices MINCED BEEF 140 5 40 55 2 oz. PECAN ROLLS...8 oz. ADDITIONAL NONSTANDARD ITEMS VEGETABLE JUICE 45 TRACE -- 887 8 oz. FRESH PEACHES 40 TRACE -- 1 1 peach BACON 85 8 70 274 2 slices SAUSAGE 60 6

  9. Odd-Z Transactinide Compound Nucleus Reactions Including the Discovery of 260Bh

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nelson, Sarah L.

    Several reactions producing odd-Z transactinide compound nuclei were studiedwith the 88-Inch Cyclotron and the Berkeley Gas-Filled Separator at the Lawrence Berkeley National Laboratory. The goal was to produce the same compound nucleus ator near the same excitation energy with similar values of angular momentum via differentnuclear reactions. In doing so, it can be determined if there is a preference in entrancechannel, because under these experimental conditions the survival portion of Swiatecki, Siwek-Wilcznska, and Wilczynski's"Fusion By Diffusion" model is nearly identical forthe two reactions. Additionally, because the same compound nucleus is produced, theexit channel is the same. Four compound nuclei were examined in this study: 258Db, 262Bh, 266Mt, and 272Rg. These nuclei were produced by using very similar heavy-ion induced-fusion reactions which differ only by one proton in the projectile or target nucleus (e.g.: 50Ti + 209Bi vs. 51V + 208Pb). Peak 1n exit channel cross sections were determined for each reaction in each pair, and three of the four pairs' cross sections were identical within statistical uncertainties. This indicates there is not an obvious preference of entrancechannel in these paired reactions. Charge equilibration immediately prior to fusionleading to a decreased fusion barrier is the likely cause of this phenomenon. In addition to this systematic study, the lightest isotope of element 107, bohrium, was discovered in the 209Bi( 52Cr,n) reaction. 260Bh was found to decay by emission of a 10.16 MeV alpha particle with a half-life of 35more » $$+19\\atop{-9}$$ ms. The cross section is 59 pb at an excitation energy of 15.0 MeV. The effect of the N = 152 shell is also seen in this isotope's alpha particle energy, the first evidence of such an effect in Bh. All reactions studied are also compared to model predictions by Swiatecki, Siwek-Wilcznska, and Wilczynski 's" Fusion By Diffusion " theory.« less

  10. Environmental Levels of the Antiviral Oseltamivir Induce Development of Resistance Mutation H274Y in Influenza A/H1N1 Virus in Mallards

    PubMed Central

    Järhult, Josef D.; Söderström, Hanna; Orozovic, Goran; Gunnarsson, Gunnar; Bröjer, Caroline; Latorre-Margalef, Neus; Fick, Jerker; Grabic, Roman; Lennerstrand, Johan; Waldenström, Jonas; Lundkvist, Åke; Olsen, Björn

    2011-01-01

    Oseltamivir (Tamiflu®) is the most widely used drug against influenza infections and is extensively stockpiled worldwide as part of pandemic preparedness plans. However, resistance is a growing problem and in 2008–2009, seasonal human influenza A/H1N1 virus strains in most parts of the world carried the mutation H274Y in the neuraminidase gene which causes resistance to the drug. The active metabolite of oseltamivir, oseltamivir carboxylate (OC), is poorly degraded in sewage treatment plants and surface water and has been detected in aquatic environments where the natural influenza reservoir, dabbling ducks, can be exposed to the substance. To assess if resistance can develop under these circumstances, we infected mallards with influenza A/H1N1 virus and exposed the birds to 80 ng/L, 1 µg/L and 80 µg/L of OC through their sole water source. By sequencing the neuraminidase gene from fecal samples, we found that H274Y occurred at 1 µg/L of OC and rapidly dominated the viral population at 80 µg/L. IC50 for OC was increased from 2–4 nM in wild-type viruses to 400–700 nM in H274Y mutants as measured by a neuraminidase inhibition assay. This is consistent with the decrease in sensitivity to OC that has been noted among human clinical isolates carrying H274Y. Environmental OC levels have been measured to 58–293 ng/L during seasonal outbreaks and are expected to reach µg/L-levels during pandemics. Thus, resistance could be induced in influenza viruses circulating among wild ducks. As influenza viruses can cross species barriers, oseltamivir resistance could spread to human-adapted strains with pandemic potential disabling oseltamivir, a cornerstone in pandemic preparedness planning. We propose surveillance in wild birds as a measure to understand the resistance situation in nature and to monitor it over time. Strategies to lower environmental levels of OC include improved sewage treatment and, more importantly, a prudent use of antivirals. PMID:21931841

  11. Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274 → Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD + and NADP +

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leitgeb, Stefan; Petschacher, Barbara; Wilson, David K.

    2005-01-11

    Aldo-keto reductases of family 2 employ single site replacement Lys → Arg to switch their cosubstrate preference from NADPH to NADH. X-ray crystal structures of Lys-274 → Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD + and NADP + were determined at a resolution of 2.4 and 2.3 Å, respectively. Due to steric conflicts in the NADP +-bound form, the arginine side chain must rotate away from the position of the original lysine side chain, thereby disrupting a network of direct and water-mediated interactions between Glu-227, Lys-274 and the cofactor 2'-phosphate and 3'-hydroxy groups. Because anchoring contactsmore » of its Glu-227 are lost, the coenzyme-enfolding loop that becomes ordered upon binding of NAD(P) + in the wild-type remains partly disordered in the NADP +-bound mutant. The results delineate a catalytic reaction profile for the mutant in comparison to wild-type.« less

  12. Explosive Performance Modification by Cosolidification of Ammonium Nitrate with Fuels

    DTIC Science & Technology

    1976-10-01

    6.18 6.58 6.38 1.48 Halt I& Fraca 70 30 2.49 3.00 2.74 5.90 5.90 1.54 Cocryst . 70 30 2.64 2.9 25 5.85 5.60 S5.73 1.533 Halt 70 30 2.72 2.74 2.73 1.46...50 0.76 0.86 0.81 Failing 1.55 Melt -4 F~eon 44 56 0.91 - 0.91 1.59 Cocryst . 44 56 1.98 2.13 2.06 5.81 5.23 5.52 1.55 Melt/quick freeze 44 56 0 0.15

  13. Supplemental Environmental Assessment for the Nuclear and Space Security Tactics Training Center Project AFSPC053012 for Air Force Security Forces at Camp Guernsey, Wyoming

    DTIC Science & Technology

    2010-02-01

    8217Ŕ IPACE: lfCUNTY TACTlet lRAINIIIG CI! NT1 !IIt (NIITTC) /lllfll!tA DI!W!l.OPI&I!NT JI\\AH c co -c._ -.; Q) ~::: Ill~ +-’ ~~ ·- ~~ (f) ti li LA N...Manager WMD- CFMO 3919 Central Ave. Cheyenne, WY 82001 (307) 772-5066 (o) (307) 274-0844 ( cell ) --- - -Original Message----- From: Lloyd, Dee W Mr...772-5066 (o) (307) 274-0844 ( cell ) -----Original Message----- From: Pesenti, Cathryn M Civ USAF AFGSC 90 CES/CEV [mailto:Cathryn.Pesenti@warren

  14. Limited effectiveness of patent blue dye in addition to isotope scanning for identification of sentinel lymph nodes: Cross-sectional real-life study in 1024 breast cancer patients.

    PubMed

    Rauch, Philippe; Merlin, Jean-Louis; Leufflen, Lea; Salleron, Julia; Harlé, Alexandre; Olivier, Pierre; Marchal, Frédéric

    2016-09-01

    Although morbidity is reduced when sentinel lymph node (SLN) biopsy is performed with dual isotopic and blue dye identification, the effectiveness of adding blue dye to radioisotope remains debated because side effects including anaphylactic reactions. Using data from a prospectively maintained database, 1884 lymph node-negative breast cancer patients who underwent partial mastectomy with SLN mapping by a dual-tracer using patent blue dye (PBD) and radioisotope were retrospectively studied between January 2000 and July 2013. Patients with tumors <3 cm and with >1 node detected by one of the two techniques (N = 1024) were included in this real-life cross-sectional study. Among the 1024 patients, 274 had positive SLN detected by isotopic and/or PBD staining. Only 4 patients having no detectable radioactivity in the axilla had SLN identified only by PBD staining (blue-only) while 26 patients had SLN only identified by isotopic detection (hot-only) illustrating failure rates of 9.5% (26/274) and 1.5% (4/274), respectively. Among these four patients, two had negative lymphoscintigraphy. Therefore, the contribution of PBD to metastatic nodes identification was relevant for only 2/274 patients (0.8%). Three patients (0.3%) had an allergic reaction with PBD, and anaphylactic shock occurred in two cases (0.2%). The added-value of PBD to reduce the false-negative rate of SLN mapping is only limited to the rare cases in which no radioactivity is detectable in the axilla (<1%). When a radioisotope mapping agent is available, the use of PBD should be avoided, because it can induce anaphylaxis. Copyright © 2016 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  15. CD274/PD-L1 gene amplification and PD-L1 protein expression are common events in squamous cell carcinoma of the oral cavity.

    PubMed

    Straub, Melanie; Drecoll, Enken; Pfarr, Nicole; Weichert, Wilko; Langer, Rupert; Hapfelmeier, Alexander; Götz, Carolin; Wolff, Klaus-Dietrich; Kolk, Andreas; Specht, Katja

    2016-03-15

    Immunomodulatory therapies, targeting the immune checkpoint receptor-ligand complex PD-1/PD-L1 have shown promising results in early phase clinical trials in solid malignancies, including carcinomas of the head and neck. In this context, PD-L1 protein expression has been proposed as a potentially valuable predictive marker. In the present study, expression of PD-L1 and PD-1 was evaluated by immunohistochemistry in 80 patients with predominantly HPV-negative oral squamous cell carcinomas and associated nodal metastasis. In addition, CD274/PD-L1 gene copy number status was assessed by fluorescence in situ hybridization analysis. PD-L1 expression was detected in 36/80 (45%) cases and concordance of PD-L1 expression in primary tumor and corresponding nodal metastasis was present in only 20/28 (72%) cases. PD-1 expression was found in tumor-infiltrating lymphocytes (TILs) but not in tumor cells. CD274/PD-L1 gene amplification was detected in 19% of cases, with high level PD-L1 amplification present in 12/80 (15%), and low level amplification in 3/80 (4%). Interestingly, CD274/PD-L1 gene amplification was associated with positive PD-L1 immunostaining in only 73% of cases. PD-L1 copy number status was concordant in primary tumor and associated metastases. Clinically, PD-L1 tumor immunopositivity was associated with a higher risk for nodal metastasis at diagnosis, overall tumor related death und recurrence. Based on our findings we propose to include PD-L1 copy number status in addition to protein status in screening programs for future clinical trials with immunotherapeutic strategies targeting the PD-1/PD-L1 axis.

  16. CD274/PD-L1 gene amplification and PD-L1 protein expression are common events in squamous cell carcinoma of the oral cavity

    PubMed Central

    Straub, Melanie; Drecoll, Enken; Pfarr, Nicole; Weichert, Wilko; Langer, Rupert; Hapfelmeier, Alexander; Götz, Carolin; Wolff, Klaus-Dietrich; Kolk, Andreas; Specht, Katja

    2016-01-01

    Immunomodulatory therapies, targeting the immune checkpoint receptor-ligand complex PD-1/PD-L1 have shown promising results in early phase clinical trials in solid malignancies, including carcinomas of the head and neck. In this context, PD-L1 protein expression has been proposed as a potentially valuable predictive marker. In the present study, expression of PD-L1 and PD-1 was evaluated by immunohistochemistry in 80 patients with predominantly HPV-negative oral squamous cell carcinomas and associated nodal metastasis. In addition, CD274/PD-L1 gene copy number status was assessed by fluorescence in situ hybridization analysis. PD-L1 expression was detected in 36/80 (45%) cases and concordance of PD-L1 expression in primary tumor and corresponding nodal metastasis was present in only 20/28 (72%) cases. PD-1 expression was found in tumor-infiltrating lymphocytes (TILs) but not in tumor cells. CD274/PD-L1 gene amplification was detected in 19% of cases, with high level PD-L1 amplification present in 12/80 (15%), and low level amplification in 3/80 (4%). Interestingly, CD274/PD-L1 gene amplification was associated with positive PD-L1 immunostaining in only 73% of cases. PD-L1 copy number status was concordant in primary tumor and associated metastases. Clinically, PD-L1 tumor immunopositivity was associated with a higher risk for nodal metastasis at diagnosis, overall tumor related death und recurrence. Based on our findings we propose to include PD-L1 copy number status in addition to protein status in screening programs for future clinical trials with immunotherapeutic strategies targeting the PD-1/PD-L1 axis. PMID:26918453

  17. Synergistic Combination of Novel Tubulin Inhibitor ABI-274 and Vemurafenib Overcome Vemurafenib Acquired Resistance in BRAFV600E Melanoma

    PubMed Central

    Wang, Jin; Chen, Jianjun; Miller, Duane D.; Li, Wei

    2013-01-01

    Acquired clinical resistance to vemurafenib, a selective BRAFV600E inhibitor, arises frequently after short term chemotherapy. Since inhibitions of targets in the RAF-MEK-ERK pathway result in G0/G1 cell cycle arrest, vemurafenib-resistant cancer cells are expected to escape this cell cycle arrest and progress to subsequent G2/M phase. We hypothesized that a combined therapy using vemurafenib with a G2/M phase blocking agent will trap resistant cells and overcome vemurafenib resistance. To test this hypothesis, we first determined the combination index (CI) values of our novel tubulin inhibitor ABI-274 and vemurafenib on parental human A375 and MDA-MB-435 melanoma cell lines to be 0.32 and 0.1, respectively, suggesting strong synergy for the combination. We then developed an A375RF21 subline with significant acquired resistance to vemurafenib and confirmed the strong synergistic effect. Next we studied the potential mechanisms of overcoming vemurafenib resistance. Flow cytometry confirmed that the combination of ABI-274 and vemurafenib synergistically arrested cells in G1/G2/M phase, and significantly increased apoptosis in both parental A375 and the vemurafenib-resistant A375RF21 cells. Western blot analysis revealed that the combination treatment effectively reduced the level of phosphorylated and total AKT, activated the apoptosis cascade, and increased cleaved caspase-3 and cleaved PARP, but had no significant influence on the level of ERK phosphorylation. Finally, in vivo co-administration of vemurafenib with ABI-274 showed strong synergistic efficacy in the vemurafenib-resistant xenograft model in nude mice. Overall, these results offer a rational combination strategy to significantly enhance the therapeutic benefit in melanoma patients who inevitably become resistant to current vemurafenib therapy. PMID:24249714

  18. Anomaly of the composition of the F-2 equatorial region of the ionosphere during the hours after sunset according to data from the mass-spectrometer experiment on the Cosmos-274

    NASA Technical Reports Server (NTRS)

    Gaydukov, V. Y.; Istomin, V. G.; Romanovskiy, Y. A.

    1979-01-01

    A mass spectrometer on board Cosmos-274 measured concentrations of light atoms and ions. While traversing the geomagnetic equator during the evening hours it recorded on anomalous drop in ionized molecular oxygen and ionized atomic oxygen and nitrogen. A similar, less dramatic, decline was observed in the concentration of neutral atomic oxygen. A possible explanation for this and previously observed behavior is an ascent in altitude of the F layer in the hours after sunset, a possibility which is supported by calculations.

  19. Interactions between the promoter and first intron are involved in transcriptional control of alpha 1(I) collagen gene expression.

    PubMed Central

    Bornstein, P; McKay, J; Liska, D J; Apone, S; Devarayalu, S

    1988-01-01

    The first intron of the human collagen alpha 1(I) gene contains several positively and negatively acting elements. We have studied the transcription of collagen-human growth hormone fusion genes, containing deletions and rearrangements of collagen intronic sequences, by transient transfection of chick tendon fibroblasts and NIH 3T3 cells. In chick tendon fibroblasts, but not in 3T3 cells, inversion of intronic sequences containing a previously studied 274-base-pair segment, A274, resulted in markedly reduced human growth hormone mRNA levels as determined by an RNase protection assay. This inhibitory effect was largely alleviated when deletions were introduced in the collagen promoter of plasmids containing negatively oriented intronic sequences. Evidence for interaction of the promoter with the intronic segment, A274, was obtained by gel mobility shift assays. We suggest that promoter-intron interactions, mediated by DNA-binding proteins, regulate collagen gene transcription. Inversion of intronic segments containing critical interactive elements might then lead to an altered geometry and reduced activity of a transcriptional complex in those cells with sufficiently high levels of appropriate transcription factors. We further suggest that the deleted promoter segment plays a key role in directing DNA interactions involved in transcriptional control. Images PMID:3211130

  20. The 274th Forward Surgical Team experience during Operation Enduring Freedom.

    PubMed

    Peoples, George E; Gerlinger, Tad; Craig, Robert; Burlingame, Brian

    2005-06-01

    The 274th Forward Surgical Team (FST) was deployed in support of Operation Enduring Freedom from October 14, 2001 to May 8, 2002. During this period, the FST was asked to perform many nondoctrinal missions. The FST was tasked with functioning as a mini-combat support hospital during the earlier phases of Operation Enduring Freedom, performing in-flight surgical procedures and resuscitation of combat wounded, conducting split operations with surgical coverage of both Karshi and Khanabad, Uzbekistan, and Bagram, Afghanistan, and leading the multinational medical coalition assembled for Operation Anaconda and other combat operations staged from Bagram. Overall, the 274th FST took care of approximately 90% of U.S. combat casualties during this period and treated a total of 221 combat casualties. The FST treated 103 total surgical cases, including 73 with combat wounds. At the time, this experience with combat casualties and the surgical care of combat wounds was the largest since the Persian Gulf War. More importantly, this account describes the flow, frequency, and type of combat casualties seen in a low-intensity conflict like that being waged currently in Afghanistan. It is hoped that this depiction will aid in the preparation, equipping, and overall utilization of surgical assets in similar future conflicts.

  1. Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone.

    PubMed

    López-Causapé, Carla; Sommer, Lea Mette; Cabot, Gabriel; Rubio, Rosa; Ocampo-Sosa, Alain A; Johansen, Helle Krogh; Figuerola, Joan; Cantón, Rafael; Kidd, Timothy J; Molin, Soeren; Oliver, Antonio

    2017-07-17

    Emergence of epidemic clones and antibiotic resistance development compromises the management of Pseudomonas aeruginosa cystic fibrosis (CF) chronic respiratory infections. Whole genome sequencing (WGS) was used to decipher the phylogeny, interpatient dissemination, WGS mutator genotypes (mutome) and resistome of a widespread clone (CC274), in isolates from two highly-distant countries, Australia and Spain, covering an 18-year period. The coexistence of two divergent CC274 clonal lineages was revealed, but without evident geographical barrier; phylogenetic reconstructions and mutational resistome demonstrated the interpatient transmission of mutators. The extraordinary capacity of P. aeruginosa to develop resistance was evidenced by the emergence of mutations in >100 genes related to antibiotic resistance during the evolution of CC274, catalyzed by mutator phenotypes. While the presence of classical mutational resistance mechanisms was confirmed and correlated with resistance phenotypes, results also showed a major role of unexpected mutations. Among them, PBP3 mutations, shaping up β-lactam resistance, were noteworthy. A high selective pressure for mexZ mutations was evidenced, but we showed for the first time that high-level aminoglycoside resistance in CF is likely driven by mutations in fusA1/fusA2, coding for elongation factor G. Altogether, our results provide valuable information for understanding the evolution of the mutational resistome of CF P. aeruginosa.

  2. Toxicity evaluation of prodigiosin from Serratia marcescens in a Caenorhabditis elegans model

    NASA Astrophysics Data System (ADS)

    Seah, Siew-Wei; Nathan, Sheila; Wan, Kiew-Lian

    2016-11-01

    Serratia marcescens produces several secondary metabolites, including a red antimicrobial pigment, prodigiosin. There is considerable interest in prodigiosin and its derivatives due to their anticancer and immunosuppressive properties. Prodigiosin has also become the main choice of red dye in textiles. As prodigiosin has potentially high commercial value, there is a demand to develop high-throughput and cost-effective bioprocesses for prodigiosin production. However little is still known about its toxicity. This study was carried out to investigate the toxicity effect of prodigiosin. To determine if prodigiosin was potentially toxic to eukaryotic systems, the S. marcescens ATCC 274 wild type (Sma 274) and the non-prodigiosin producer S. marcescens Bizio WF mutant ATCC 29635 (WF mutant) were grown under the optimised conditions for prodigiosin production and fed to the nematode Caenorhabditis elegans. The mean time to death (TDmean) for Sma 274-infected worms assayed on agar was 112.6 hours while the WF mutant culture had a TDmean of 104.4 hours. However, the nematode killing kinetics were not significantly different between the prodigiosin-producing and non-producing S. marcescens strains (p>0.05). In lieu of its non-toxic property, prodigiosin has the potential to be developed for safe therapeutic applications and as a safe environmental friendly bio-dye.

  3. Novel Structure of Enterococcus faecium-Originated ermB-Positive Tn1546-Like Element in Staphylococcus aureus.

    PubMed

    Wan, Tsai-Wen; Hung, Wei-Chun; Tsai, Jui-Chang; Lin, Yu-Tzu; Lee, Hao; Hsueh, Po-Ren; Lee, Tai-Fen; Teng, Lee-Jene

    2016-10-01

    We determined the resistance determinants in 274 erythromycin-resistant methicillin-susceptible Staphylococcus aureus (MSSA) isolates during a 13-year period, 2000 to 2012. The resistance phenotypes, inducible macrolide-lincosamide-streptogramin (iMLS), constitutive MLS (cMLS), and macrolide-streptogramin (MS) resistance phenotypes, were examined by a double-disk diffusion D test. The ermB gene was more frequent (35%; 97/274) than ermC (27%; 75/274) or ermA (21%; 58/274). All 97 ermB-positive isolates harbored Tn551 and IS1216V The majority (89/97) of ermB-positive isolates displayed the cMLS phenotype and carried mobile element structure (MES)-like structures, which has been previously reported in sequence type 59 (ST59) methicillin-resistant S. aureus (MRSA). The remaining 8 ermB-carrying isolates, belonging to ST7 (n = 4), ST5 (n = 3), and ST59 (n = 1), were sasK intact and did not carry MES-like structures. Unlike a MES-like structure that was located on the chromosome, the ermB elements on sasK-intact isolates were located on plasmids by S1 nuclease pulsed-field gel electrophoresis (PFGE) analysis and conjugation tests. Sequence data for the ermB-containing region (14,566 bp) from ST59 NTUH_3874 revealed that the best match was a Tn1546-like element in plasmid pMCCL2 DNA (GenBank accession number AP009486) of Macrococcus caseolyticus Tn1546 is recognized as an enterococcal transposon and was known from the vancomycin resistance gene cluster in vancomycin-resistant Enterococcus (VRE). So far, acquisitions of Tn1546 in S. aureus have occurred in clonal complex 5 (CC5) MRSA, but not in MSSA. This is the first report that MSSA harbors an Enterococcus faecium-originated ermB-positive Tn1546-like element located on a plasmid. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  4. Rapid Evolution of the Solar Atmosphere during the Impulsive Phase of a Microflare Observed with the Extreme-ultraviolet Imaging Spectrometer aboard Hinode: Hints of Chromospheric Magnetic Reconnection

    NASA Astrophysics Data System (ADS)

    Brosius, Jeffrey W.

    2013-11-01

    We obtained rapid cadence (11.2 s) EUV stare spectra of a solar microflare with the Extreme-ultraviolet Imaging Spectrometer aboard Hinode. The intensities of lines formed at temperatures too cool to be found in the corona brightened by factors around 16 early during this event, indicating that we observed a site of energy deposition in the chromosphere. We derive the density evolution of the flare plasma at temperature around 2 MK from the intensity ratio of Fe XIV lines at 264.789 Å and 274.204 Å. From both lines we removed the bright pre-flare quiescent emission, and from 274.204 we removed the blended emission of Si VII λ274.180 based on the Si VII λ274.180/275.361 intensity ratio, which varies only slightly with density. In this way the flare electron density is derived with emission from only the flare plasma. The density increased by an order of magnitude from its pre-flare quiescent average of (3.43 ± 0.19) × 109 cm-3 to its maximum impulsive phase value of (3.04 ± 0.57) × 1010 cm-3 in 2 minutes. The fact that this rapid increase in density is not accompanied by systematic, large upward velocities indicates that the density increase is not due to the filling of loops with evaporated chromospheric material, but rather due to material being directly heated in the chromosphere, likely by magnetic reconnection. The density increase may be due to a progression of reconnection sites to greater depths in the chromosphere, where it has access to larger densities, or it may be due to compression of 2 MK plasma by the 10 MK plasma as it attempts to expand against the high-density chromospheric plasma.

  5. 48 CFR 211.274-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... on the workforce through increased productivity and efficiency; and (e) Ensures item level traceability throughout lifecycle to strengthen supply chain integrity, enhance cyber security, and combat...

  6. The Influence of Intrinsic and Extrinsic Factors on Neurogenesis

    DTIC Science & Technology

    2008-07-31

    ACG AAT TGA GCA ATA ACG GTG ATG GCG ATA GTA AGA ACA GTT C 49 Table II-2. Sequence information and physical characteristics of...CTC TGA GCT AGT 550 50 24 60.15 3’mAT-O GTG ACA CTA GCA GAC CAG ATT CCT 550 50 24 61.08 5’mAT-N GCC TCT GAG CTA GTA TGT GTC ATC 274 50 24 59.46 3...8217mAT-N CCA TCA CCT TCT CCT TTC TAG GTC 274 50 24 61.64 5’rAT-O TTT AGC TCA GTG GTA GAG CGC 257 52 21 56 3’rAT-O GTT TCT GCC CTT TCC AAC TGC 257 52 21

  7. 21 CFR 558.274 - Hygromycin B.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... whipworms (Trichuris suis) Withdraw 15 days before slaughter 000986012286 017790 054771 (ii) 12 Tylosin 10... (Oesophagostomum dentatum), and whipworms (Trichuris suis); growth promotion and feed efficiency Feed continuously...

  8. Phylogenetic distribution of roseobacticides in the Roseobacter group and their effect on microalgae.

    PubMed

    Sonnenschein, Eva C; Phippen, Christopher Broughton William; Bentzon-Tilia, Mikkel; Rasmussen, Silas Anselm; Nielsen, Kristian Fog; Gram, Lone

    2018-06-01

    The Roseobacter-group species Phaeobacter inhibens produces the antibacterial tropodithietic acid (TDA) and the algaecidal roseobacticides with both compound classes sharing part of the same biosynthetic pathway. The purpose of this study was to investigate the production of roseobacticides more broadly in TDA-producing roseobacters and to compare the effect of producers and non-producers on microalgae. Of 33 roseobacters analyzed, roseobacticide production was a unique feature of TDA-producing P. inhibens, P. gallaeciensis and P. piscinae strains. One TDA-producing Phaeobacter, 27-4, did not produce roseobacticides, possibly due to a transposable element. TDA-producing Ruegeria and Pseudovibrio did not produce roseobacticides. Addition of roseobacticide-containing bacterial extracts affected the growth of the microalgae Rhodomonas salina, Thalassiosira pseudonana and Emiliania huxleyi, while growth of Tetraselmis suecica was unaffected. During co-cultivation, growth of E. huxleyi was initially stimulated by the roseobacticide producer DSM 17395, while the subsequent decline in algal cell numbers during senescence was enhanced. Strain 27-4 that does not produce roseobacticides had no effect on algal growth. Both bacterial strains, DSM 17395 and 27-4, grew during co-cultivation presumably utilizing algal exudates. Furthermore, TDA-producing roseobacters have potential as probiotics in marine larviculture and it is promising that the live feed Tetraselmis was unaffected by roseobacticides-containing extracts. © 2018 Society for Applied Microbiology and John Wiley & Sons Ltd.

  9. XTE J1946+274 = GRO J1944+26: An Enigmatic Be/X-ray Binary

    NASA Technical Reports Server (NTRS)

    Wilson, Colleen A.; Finger, Mark H.; Coe, M. J.; Negueruela, Ignacio; Six, N. Frank (Technical Monitor)

    2002-01-01

    XTE J1946+274 = GRO J1944+26 is a 15.8-s Be/X-ray pulsar discovered simultaneously in 1998 September with the, Burst and Transient Source Experiment (BATSE) on the Compton Gamma Ray Observatory (CGRO) and the All-Sky Monitor (ASM) on the Rossi X-ray Timing Explorer (RXTE). Pulse timing analysis yielded an orbital period of 169.2 days, a moderate eccentricity of 0.33, and implied a mass function of 9.7 solar mass. We observed evidence for an accretion disk, a correlation between measured spin-up rate and flux, which was fitted to obtain a distance estimate of 9.2 +/- 1.0 kpc. XTE J1946+274 remained active from 1998 September - 2001 July, undergoing 13 outbursts that were not locked in orbital phase. Comparing RXTE PCA observations from the initial bright outburst in 1998 and the last pair of outburst in 2001, we found energy and intensity dependent pulse profile variations in both outbursts and hardening spectra with increasing intensity during the fainter 2001 outbursts. In 2001 July, optical H(alpha) observations indicate a density perturbation appeared in the Be disk as the X-ray outbursts ceased. We propose that the equatorial plane of the Be star is inclined with respect to the orbital plane in this system and that this inclination may produce the unusual outburst behavior of the system.

  10. 7 CFR 1150.274 - Certification standards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the organization; (4) Sources from which the organization's operating funds are derived; (5) Functions... objectives of the Act. (b) The primary considerations in determining the eligibility of an organization shall...

  11. 33 CFR 274.3 - References.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Surveillance Guide, U.S. Army Environmental Hygiene Agency, January 1975. (d) Guide for the Medical Surveillance of Pest Controllers, U.S. Army Environmental Hygiene Agency, March 1976, as amended. (e) Pesticide...

  12. 33 CFR 274.3 - References.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Surveillance Guide, U.S. Army Environmental Hygiene Agency, January 1975. (d) Guide for the Medical Surveillance of Pest Controllers, U.S. Army Environmental Hygiene Agency, March 1976, as amended. (e) Pesticide...

  13. Department of Defense Prime Contract Awards By State, Fiscal Year 1996.

    DTIC Science & Technology

    1996-01-01

    652 0 0 Monona 175 0 0 0 0 175 Muscatine 1,762 895 787 43 88 51- Plymouth 356 0 0 0 0 128 Polk 15,738 3,477 118 906 4,172 6,647 Pottawattamie 46 46 0 0...1,644 87 48 4,748 0 Kentucky 874,094 340,076 65,228 30,241 62,043 36,221 Allen 113 0 0 0 0 113 Anderson 274 0 0 0 274 0 Barren 188 0 0 0 0 188 Bell 253 0...680,880 1,132,700 40,828 4,793 Nantucket 140 0 0 0 40 100 Norfolk 288,053 85,305 155,978 17,406 6,306 22,184 Plymouth 9,657 2,894 878 1,015 892 1,378

  14. 30 CFR 27.4 - Application procedures and requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... Department of Labor, Mine Safety and Health Administration, Approval and Certification Center, 765 Technology... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  15. 83. OVERVIEW OF PARTIALLY COMPLETED POWERHOUSE WITH TWO UNITS IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    83. OVERVIEW OF PARTIALLY COMPLETED POWERHOUSE WITH TWO UNITS IN OPERATION, LOOKING UPSTREAM, Print No. 274, June 1904 - Electron Hydroelectric Project, Along Puyallup River, Electron, Pierce County, WA

  16. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction....275, this subpart does not cover construction programs such as the: (a) Maintenance and Improvement...

  17. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction....275, this subpart does not cover construction programs such as the: (a) Maintenance and Improvement...

  18. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction....275, this subpart does not cover construction programs such as the: (a) Maintenance and Improvement...

  19. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction....275, this subpart does not cover construction programs such as the: (a) Maintenance and Improvement...

  20. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction....275, this subpart does not cover construction programs such as the: (a) Maintenance and Improvement...

  1. 7 CFR 274.5 - Record retention and forms security.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... reconciliation process. (c) Accountable documents. (1) EBT cards shall be considered accountable documents. The... validation of inventory controls and records by parties not otherwise involved in maintaining control records...

  2. 7 CFR 274.5 - Record retention and forms security.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... reconciliation process. (c) Accountable documents. (1) EBT cards shall be considered accountable documents. The... validation of inventory controls and records by parties not otherwise involved in maintaining control records...

  3. 7 CFR 274.5 - Record retention and forms security.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... reconciliation process. (c) Accountable documents. (1) EBT cards shall be considered accountable documents. The... validation of inventory controls and records by parties not otherwise involved in maintaining control records...

  4. Mohave Valley Land Conveyance Act of 2011

    THOMAS, 112th Congress

    Sen. McCain, John [R-AZ

    2011-03-09

    Senate - 01/13/2012 Placed on Senate Legislative Calendar under General Orders. Calendar No. 274. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  5. 77 FR 30220 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ... proof Flood Insurance Study and FIRM available at the address cited below for each community. The BFEs... Areas of 175. Kaufman County. Approximately 1 mile +342 downstream of State Highway 274. Duck Creek...

  6. 75 FR 62057 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-07

    ... buildings. Comments on any aspect of the Flood Insurance Study and FIRM, other than the proposed BFEs, will... State Highway 274. Duck Creek Approximately 925 feet None +458 Unincorporated Areas of downstream of...

  7. 7 CFR 274.5 - Record retention and forms security.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... control logs, or similar controls from the point of initial receipt through the issuance and.... (2) For notices of change which initiate, update or terminate the master issuance file, the State...

  8. 10 CFR 150.20 - Recognition of Agreement State licenses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Reciprocity § 150.20 Recognition of... before engaging in activities under reciprocity, because of an emergency or other reason, the Regional...

  9. 10 CFR 150.20 - Recognition of Agreement State licenses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Reciprocity § 150.20 Recognition of... before engaging in activities under reciprocity, because of an emergency or other reason, the Regional...

  10. 10 CFR 150.20 - Recognition of Agreement State licenses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Reciprocity § 150.20 Recognition of... before engaging in activities under reciprocity, because of an emergency or other reason, the Regional...

  11. 26 CFR 1.274-5 - Substantiation requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... indirectly to the employer through credit cards or otherwise) for travel, entertainment, gifts, and the use... for the driver, or only for the driver plus a folding jump seat. (I) Dump trucks (including garbage...

  12. 26 CFR 1.274-5 - Substantiation requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... indirectly to the employer through credit cards or otherwise) for travel, entertainment, gifts, and the use... for the driver, or only for the driver plus a folding jump seat. (I) Dump trucks (including garbage...

  13. 26 CFR 1.274-5 - Substantiation requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... indirectly to the employer through credit cards or otherwise) for travel, entertainment, gifts, and the use... for the driver, or only for the driver plus a folding jump seat. (I) Dump trucks (including garbage...

  14. 26 CFR 1.274-5 - Substantiation requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... indirectly to the employer through credit cards or otherwise) for travel, entertainment, gifts, and the use... for the driver, or only for the driver plus a folding jump seat. (I) Dump trucks (including garbage...

  15. 78 FR 76293 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-17

    .... Comments Due: 5 p.m. ET 12/23/13. Docket Numbers: RP14-274-000. Applicants: NGO Transmission, Inc. Description: NGO Transmission, Inc. submits tariff filing per 154.204: NGO Transmission, Inc.--Negotiated Rate...

  16. 49 CFR 178.274 - Specifications for UN portable tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... transported; or (ii) Properly passivated or neutralized by chemical reaction, if applicable; or (iii) For.... All stop-valves with screwed spindles must close by a clockwise motion of the handwheel. For other...

  17. Vascular Cures

    MedlinePlus

    ... SV Gives Search ©2017 Vascular Cures is a tax-exempt, nonprofit organization tax ID#: 94-2825216 as described in the Section ... 3) of the Internal Revenue Code. Donations are tax deductible. 274 Redwood Shores Parkway, #717, Redwood City, ...

  18. 26 CFR 1.274-5 - Substantiation requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... bill from the payee, ordinarily would establish the element of cost. In contrast, a cancelled check... evidence. (iii) Employer. For purposes of this section, the term employer includes an agent of the employer...

  19. Fabrication of in-situ grown graphene reinforced Cu matrix composites

    NASA Astrophysics Data System (ADS)

    Chen, Yakun; Zhang, Xiang; Liu, Enzuo; He, Chunnian; Shi, Chunsheng; Li, Jiajun; Nash, Philip; Zhao, Naiqin

    2016-01-01

    Graphene/Cu composites were fabricated through a graphene in-situ grown approach, which involved ball-milling of Cu powders with PMMA as solid carbon source, in-situ growth of graphene on flaky Cu powders and vacuum hot-press sintering. SEM and TEM characterization results indicated that graphene in-situ grown on Cu powders guaranteed a homogeneous dispersion and a good combination between graphene and Cu matrix, as well as the intact structure of graphene, which was beneficial to its strengthening effect. The yield strength of 244 MPa and tensile strength of 274 MPa were achieved in the composite with 0.95 wt.% graphene, which were separately 177% and 27.4% enhancement over pure Cu. Strengthening effect of in-situ grown graphene in the matrix was contributed to load transfer and dislocation strengthening.

  20. Site-directed mutagenesis of the chemokine receptor CXCR6 suggests a novel paradigm for interactions with the ligand CXCL16.

    PubMed

    Petit, Sarah J; Chayen, Naomi E; Pease, James E

    2008-08-01

    Chemokine receptor CXCR6 mediates the chemotaxis and adhesion of leukocytes to soluble and membrane-anchored forms of CXCL16, and is an HIV-1 co-receptor. Here, we describe the effects of mutation of acidic extracellular CXCR6 residues on receptor function. Although most CXCR6 mutants examined were expressed at levels similar to wild-type (WT) CXCR6, an N-terminal E3Q mutant was poorly expressed, which may explain previously reported protective effects of a similar single nucleotide polymorphism, with respect to late-stage HIV-1 infection. In contrast to several other chemokine receptors, mutation of the CXCR6 N terminus and inhibition of post-translational modifications of this region were without effect on receptor function. Likewise, N-terminal extension of CXCL16 resulted in a protein with decent potency and efficacy in chemotaxis and not, as anticipated, a CXCR6 antagonist. D176N and E274Q CXCR6 mutants were unable to interact with soluble CXCL16, suggesting a critical role for D176 and E274 in ligand binding. Intriguingly, although unable to interact with soluble CXCL16, the E274Q mutant could promote robust adhesion to membrane-anchored CXCL16, suggesting that soluble and membrane-bound forms of CXCL16 possess distinct conformations. Collectively, our data suggest a novel paradigm for the CXCR6:CXCL16 interaction, a finding which may impact the discovery of small-molecule antagonists of CXCR6.

  1. 2. EAST PART OF SOLIDIER FIELD, LOOKING NORTHWEST TOWARD BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. EAST PART OF SOLIDIER FIELD, LOOKING NORTHWEST TOWARD BUILDING 274 AND PLUMMER STREET, FROM BALL DIAMOND IN SOUTHEAST CORNER. (Panoramic view 2/2). - Presidio of Monterey, Soldier Field, Monterey, Monterey County, CA

  2. 49 CFR 178.274 - Specifications for UN portable tanks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... welding of pressure vessels. When the manufacturing process or the materials make it necessary, the shells... strength of the tubing, such as may happen when cutting threads. Brazed joints are not authorized for...

  3. 49 CFR 178.274 - Specifications for UN portable tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... welding of pressure vessels. When the manufacturing process or the materials make it necessary, the shells... strength of the tubing, such as may happen when cutting threads. Brazed joints are not authorized for...

  4. 77 FR 28588 - Proposed Priorities-American Overseas Research Centers Program; CFDA Number 84.274A

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ... compliance costs that might result from technological innovation or anticipated behavioral changes.'' We are.... scholars conducting overseas research that is vital to understanding the history, culture, economy...

  5. Critical Limb Ischemia (CLI)

    MedlinePlus

    ... re human: Search ©2017 Vascular Cures is a tax-exempt, nonprofit organization tax ID#: 94-2825216 as described in the Section ... 3) of the Internal Revenue Code. Donations are tax deductible. 274 Redwood Shores Parkway, #717, Redwood City, ...

  6. What Is Vascular Disease?

    MedlinePlus

    ... re human: Search ©2017 Vascular Cures is a tax-exempt, nonprofit organization tax ID#: 94-2825216 as described in the Section ... 3) of the Internal Revenue Code. Donations are tax deductible. 274 Redwood Shores Parkway, #717, Redwood City, ...

  7. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  8. 40 CFR 60.276 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; (4) Flow diagram of process and emission capture equipment including other equipment or process(es... values exceeding ±15 percent of the value established under § 60.274(c) or operation at flow rates lower...

  9. 40 CFR 60.276 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...; (4) Flow diagram of process and emission capture equipment including other equipment or process(es... values exceeding ±15 percent of the value established under § 60.274(c) or operation at flow rates lower...

  10. 40 CFR 60.276 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...; (4) Flow diagram of process and emission capture equipment including other equipment or process(es... values exceeding ±15 percent of the value established under § 60.274(c) or operation at flow rates lower...

  11. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  12. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  13. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  14. 40 CFR 60.276 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...; (4) Flow diagram of process and emission capture equipment including other equipment or process(es... values exceeding ±15 percent of the value established under § 60.274(c) or operation at flow rates lower...

  15. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  16. 40 CFR 60.276 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...; (4) Flow diagram of process and emission capture equipment including other equipment or process(es... values exceeding ±15 percent of the value established under § 60.274(c) or operation at flow rates lower...

  17. 47 CFR 27.4 - Terms and definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... booster station shall be entitled to protection against interference as set forth in this part. The... be received by the public, directly or by the intermediary of relay stations.” 47 U.S.C. 153(6...

  18. 77 FR 22806 - Proposed Extension of Existing Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... annually. Total Burden Cost (capital/startup): $0. Total Burden Cost (operating/maintenance): $45,979... (Section 8(f) Payments) 1,425 ESA-100 (20 SFR 702.201) 840 LS-271 (Self Insurance Application) 60 LS-274...

  19. 33 CFR 274.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... pest control program at all civil works projects. It also presents guidance for the preparation and submission of an annual pest control summary report. ... Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST...

  20. 33 CFR 274.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pest control program at all civil works projects. It also presents guidance for the preparation and submission of an annual pest control summary report. ... Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST...

  1. 33 CFR 274.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... pest control program at all civil works projects. It also presents guidance for the preparation and submission of an annual pest control summary report. ... Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST...

  2. 33 CFR 274.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... pest control program at all civil works projects. It also presents guidance for the preparation and submission of an annual pest control summary report. ... Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST...

  3. 33 CFR 274.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... pest control program at all civil works projects. It also presents guidance for the preparation and submission of an annual pest control summary report. ... Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PEST...

  4. Consolidated bioprocessing of microalgal biomass to carboxylates by a mixed culture of cow rumen bacteria using anaerobic sequencing batch reactor (ASBR).

    PubMed

    Zhao, Baisuo; Liu, Jie; Frear, Craig; Holtzapple, Mark; Chen, Shulin

    2016-12-01

    This study employed mixed-culture consolidated bioprocessing (CBP) to digest microalgal biomass in an anaerobic sequencing batch reactor (ASBR). The primary objectives are to evaluate the impact of hydraulic residence time (HRT) on the productivity of carboxylic acids and to characterize the bacterial community. HRT affects the production rate and patterns of carboxylic acids. For the 5-L laboratory-scale fermentation, a 12-day HRT was selected because it offered the highest productivity of carboxylic acids and it synthesized longer chains. The variability of the bacterial community increased with longer HRT (R 2 =0.85). In the 5-L laboratory-scale fermentor, the most common phyla were Firmicutes (58.3%), Bacteroidetes (27.4%), and Proteobacteria (11.9%). The dominant bacterial classes were Clostridia (29.8%), Bacteroidia (27.4%), Tissierella (26.2%), and Betaproteobacteria (8.9%). Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Cooling of High Pressure Rocket Thrust Chambers with Liquid Oxygen

    NASA Technical Reports Server (NTRS)

    Price, H. G.

    1980-01-01

    An experimental program using hydrogen and oxygen as the propellants and supercritical liquid oxygen (LOX) as the coolant was conducted at 4.14 and 8.274 MN/square meters (600 and 1200 psia) chamber pressure. Data on the following are presented: the effect of LOX leaking into the combustion region through small cracks in the chamber wall; and verification of the supercritical oxygen heat transfer correlation developed from heated tube experiments; A total of four thrust chambers with throat diameters of 0.066 m were tested. Of these, three were cyclically tested to 4.14 MN/square meters (600 psia) chamber pressure until a crack developed. One had 23 additional hot cycles accumulated with no apparent metal burning or distress. The fourth chamber was operated at 8.274 MN/square meters (1200 psia) pressure to obtain steady state heat transfer data. Wall temperature measurements confirmed the heat transfer correlation.

  6. Formulation and evaluation of C-Ether fluids as lubricants useful to 260 C. [air breathing engines

    NASA Technical Reports Server (NTRS)

    Clark, F. S.; Miller, D. R.

    1980-01-01

    Three base stocks were evaluated in bench and bearing tests to determine their suitability for use at bulk oil temperatures (BOT) from -40 C to +260 C. A polyol ester gave good bearing tests at a bulk temperature of 218 C, but only a partially successful run at 274 C. These results bracket the fluid's maximum operating temperature between these values. An extensive screening program selected lubrication additives for a C-ether (modified polyphenyl ether) base stock. One formulation lubricated a bearing for 111 hours at 274 C (BOT), but this fluid gave many deposit related problems. Other C-ether blends produced cage wear or fatigue failures. Studies of a third fluid, a C-ether/disiloxane blend, consisted of bench oxidation and lubrication tests. These showed that some additives react differently in the blend than in pure C-ethers.

  7. Structure-guided investigation of lipopolysaccharide O-antigen chain length regulators reveals regions critical for modal length control.

    PubMed

    Kalynych, Sergei; Ruan, Xiang; Valvano, Miguel A; Cygler, Miroslaw

    2011-08-01

    The O-antigen component of the lipopolysaccharide (LPS) represents a population of polysaccharide molecules with nonrandom (modal) chain length distribution. The number of the repeat O units in each individual O-antigen polymer depends on the Wzz chain length regulator, an inner membrane protein belonging to the polysaccharide copolymerase (PCP) family. Different Wzz proteins confer vastly different ranges of modal lengths (4 to >100 repeat units), despite having remarkably conserved structural folds. The molecular mechanism responsible for the selective preference for a certain number of O units is unknown. Guided by the three-dimensional structures of PCPs, we constructed a panel of chimeric molecules containing parts of two closely related Wzz proteins from Salmonella enterica and Shigella flexneri which confer different O-antigen chain length distributions. Analysis of the O-antigen length distribution imparted by each chimera revealed the region spanning amino acids 67 to 95 (region 67 to 95), region 200 to 255, and region 269 to 274 as primarily affecting the length distribution. We also showed that there is no synergy between these regions. In particular, region 269 to 274 also influenced chain length distribution mediated by two distantly related PCPs, WzzB and FepE. Furthermore, from the 3 regions uncovered in this study, region 269 to 274 appeared to be critical for the stability of the oligomeric form of Wzz, as determined by cross-linking experiments. Together, our data suggest that chain length determination depends on regions that likely contribute to stabilize a supramolecular complex.

  8. XTE J1946+274 = GRO J1944+26: An Enigmatic Be/X-Ray Binary

    NASA Technical Reports Server (NTRS)

    Wilson, Colleen A.; Finger, Mark H.; Coe, M. J.; Negueruela, Ignacio

    2003-01-01

    XTE J1946+274 = GRO J1944+26 is a 15.8 s Be/X-ray pulsar discovered simultaneously in 1998 September with the Burst and Transient Source Experiment (BATSE) on the Compton Gamma Ray Observatory (CGRO) and the All-Sky Monitor (ASM) on the Rossi X-Ray Timing Explorer (RXTE). Here we present new results from BATSE and RXTE including a pulse timing analysis, spectral analysis, and evidence for an accretion disk. Our pulse timing analysis yielded an orbital period of 169.2 days, a moderate eccentricity 0.33, and implied a mass function of 9.7 solar masses. We observed evidence for an accretion disk, a correlation between measured spin-up rate and flux, which was fitted to obtain a distance estimate of 9.5 +/- 2.9 kpc. XTE J1946+274 remained active from 1998 September to 2001 July, undergoing 13 outbursts that were not locked in orbital phase. Comparing RXTE Proportional Counter Array observations from the initial bright outburst in 1998 and the last pair of outbursts in 2001, we found energy and intensity-dependent pulse profile variations in both outbursts and hardening spectra with increasing intensity during the fainter 2001 outbursts. In 2001 July, optical H alpha observations indicated that a density perturbation appeared in the Be disk as the X-ray outbursts ceased. We propose that the equatorial plane of the Be star is inclined with respect to the orbital plane in this system and that this inclination may be a factor in the unusual outburst behavior of the system.

  9. THE TRANSIENT ACCRETING X-RAY PULSAR XTE J1946+274: STABILITY OF X-RAY PROPERTIES AT LOW FLUX AND UPDATED ORBITAL SOLUTION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marcu-Cheatham, Diana M.; Pottschmidt, Katja; Kühnel, Matthias

    2015-12-10

    We present a timing and spectral analysis of the X-ray pulsar XTE J1946+274 observed with Suzaku during an outburst decline in 2010 October and compare with previous results. XTE J1946+274 is a transient X-ray binary consisting of a Be-type star and a neutron star with a 15.75 s pulse period in a 172 days orbit with 2–3 outbursts per orbit during phases of activity. We improve the orbital solution using data from multiple instruments. The X-ray spectrum can be described by an absorbed Fermi–Dirac cut-off power-law model along with a narrow Fe Kα line at 6.4 keV and a weakmore » Cyclotron Resonance Scattering Feature (CRSF) at ∼35 keV. The Suzaku data are consistent with the previously observed continuum flux versus iron line flux correlation expected from fluorescence emission along the line of sight. However, the observed iron line flux is slightly higher, indicating the possibility of a higher iron abundance or the presence of non-uniform material. We argue that the source most likely has only been observed in the subcritical (non-radiation dominated) state since its pulse profile is stable over all observed luminosities and the energy of the CRSF is approximately the same at the highest (∼5 × 10{sup 37} erg s{sup −1}) and lowest (∼5 × 10{sup 36} erg s{sup −1}) observed 3–60 keV luminosities.« less

  10. 76 FR 7189 - Trunkline Gas Company, LLC; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-09

    ... Ship Shoal T-27 Platform and appurtenant facilities located in Ship Shoal 274, Offshore Louisiana... as more fully set forth in the application, which is open to the public for inspection. The filing...

  11. Airport Development Needs: Estimating Future Costs

    DOT National Transportation Integrated Search

    1997-04-01

    As part of the FAA Reauthorization Act of 1996 (P.L. 104-264, section 274(e)), : the Congress directed the General Accounting Office (GAO) to provide an : independent assessment of airport development needs to it and to the National : Civil Aviation ...

  12. Statewide pavement friction testing 2012.

    DOT National Transportation Integrated Search

    2012-11-01

    In 2012, Dynatest conducted friction testing for the Wisconsin Department of Transportation (WisDOT) on a representative subset of its State Trunk Highway Network. Friction testing was performed at 3,394 sites in accordance with ASTM E274 using a Dyn...

  13. Genetics Home Reference: alpha-1 antitrypsin deficiency

    MedlinePlus

    ... 27(3):274-81. Review. Citation on PubMed de Serres FJ, Blanco I, Fernández-Bustillo E. Estimated ... 9. Epub 2006 Sep 27. Citation on PubMed de Serres FJ, Blanco I, Fernández-Bustillo E. Estimating ...

  14. PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue - prognostic implications and rationale for immunotherapy.

    PubMed

    Boxberg, Melanie; Steiger, Katja; Lenze, Ulrich; Rechl, Hans; von Eisenhart-Rothe, Rüdiger; Wörtler, Klaus; Weichert, Wilko; Langer, Rupert; Specht, Katja

    2018-01-01

    Therapies targeting programmed death 1-(PD-1) or its ligand (PD-L1), promoting antitumor T-cell activity have been successfully introduced into clinical practice. Clinical response correlates with PD-L1 expression by tumor cells or immune cells within the tumor microenvironment. The PD-L1/PD-1 axis and tumor microenvironment has been rarely studied in high-grade sarcomas of soft tissue (hSTS), a group of rare, genetically heterogenous and clinically aggressive tumors. We examined PD-L1 protein and CD274/PD-L1 gene copy number variations in 128 primary resected, therapy-naive hSTS using immunohistochemistry and fluorescence-in-situ hybridization. Frequency of tumoral PD-L1 expression varied widely in different disease subentities, with highest rates of positivity (40%) seen in undifferentiated pleomorphic sarcomas (UPS) and rare positivity detected in synovial sarcomas (6%). Amplification of the CD274/PD-L1 gene occurred in 14% of UPS and was rare in other subtypes. PD-L1 protein expression was significantly more frequent in CD274/PD-L1 amplified cases (p = 0.015). The subgroup of UPS was further characterized regarding the interaction between PD-L1 and the immunologic tumor microenvironment. High density of CD3+ and CD8+ tumor infiltrating lymphocytes (TILs) was significantly correlated with the presence of PD-L1 expression and seen more frequently in tumors with lower TNM stage (p = 0.024). Both, PD-L1 expression and high density lymphocytic infiltration were independent prognostic factors for a favorable overall (p = 0.001, HR 6.105 (2.041-8.258)), disease-specific (p = 0.003, HR 10.536 (2.186-50.774)) and disease-free survival (p = 0.020, HR 3.317 (1.209-9.106); values for CD8) in this particular subgroup of hSTS, whereas PD-L1 expression in TILs or CD274/PD-L1 gene amplification were not associated with outcome. These findings represent novel insights into the immune landscape of soft tissue sarcomas, in particular UPS and strengthen the rationale for immunotherapy, including targeting the PD-1/PD-L1 axis in these tumors.

  15. 76 FR 9320 - Foreign-Trade Zone 274-Butte-Silver Bow, MT; Application for Manufacturing Authority REC Silicon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... Silicon to realize logistical benefits through the use of weekly customs entry procedures. Customs duties... Avenue, NW., Washington, DC 20230-0002, and in the ``Reading Room'' section of the Board's Web site...

  16. 77 FR 274 - Combined Notice of Filings #2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    .... Applicants: Constellation Energy Commodities Group, Baltimore Gas and Electric Company, Constellation Power... that the Commission received the following electric rate filings: Docket Numbers: ER10-2172-006; ER10... Generation, LLC, Constellation NewEnergy, Inc., MXenergy Electric Inc. Description: Constellation MBR...

  17. Traffic safety facts 1995 : state alcohol estimates

    DOT National Transportation Integrated Search

    1996-01-01

    Nationwide in 1995, alcohol was involved in 41.3 percent of the traffic fatalities (8.9 percent low alcohol and 32.5 percent high alcohol), translating to 17,274 alcohol-related fatalities. These tables provide estimates of alcohol involvement in fat...

  18. 48 CFR 39.107 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.107 Contract clause. The contracting officer..., in solicitations and contracts for information technology which require security of information... information technology services or support services. [61 FR 41470, Aug. 8, 1996. Redesignated at 62 FR 274...

  19. 33 CFR 274.4 - Pesticide management.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... responsibility for using personal protective equipment and clothing provided and for following established health... from pesticide hazards. Basic health and safety practices and procedures including personal protective... maintenance of pest control equipment. Field Operating Agencies (FOA) will designate a single point of contact...

  20. 78 FR 29613 - Modification and Revocation of Air Traffic Service Routes; Jackson, MS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... structure as required to preserve the safe and efficient flow of air traffic. Environmental Review The FAA... Guthrie 156[deg] and Millsap, TX, 274[deg] radials; Millsap; Glen Rose, TX; Cedar Creek, TX; Quitman, TX...

  1. 27 CFR 24.274 - Failure to timely pay tax or file a return.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... percent for each month or fraction thereof of the delinquency, not exceeding 25 percent in the aggregate, unless it is shown that the delinquency is due to reasonable cause and not to willful neglect. (Sec. 201...

  2. 40 CFR 761.274 - Reporting PCB concentrations in samples.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... concentrations for non-liquid PCBs on a dry weight basis as micrograms of PCBs per gram of sample (ppm by weight... quotient by the total number of micrograms of PCBs on the surface to obtain the equivalent measurement of...

  3. 40 CFR 761.274 - Reporting PCB concentrations in samples.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... concentrations for non-liquid PCBs on a dry weight basis as micrograms of PCBs per gram of sample (ppm by weight... quotient by the total number of micrograms of PCBs on the surface to obtain the equivalent measurement of...

  4. 40 CFR 761.274 - Reporting PCB concentrations in samples.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... concentrations for non-liquid PCBs on a dry weight basis as micrograms of PCBs per gram of sample (ppm by weight... quotient by the total number of micrograms of PCBs on the surface to obtain the equivalent measurement of...

  5. 7 CFR 274.7 - Benefit redemption by eligible households.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... State agency shall ensure that the EBT system is capable of providing a transaction history for a period... with §§ 278.1 and 278.2(g) of this chapter. (iii) Residents of shelters for battered women and children...

  6. 7 CFR 274.7 - Benefit redemption by eligible households.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... State agency shall ensure that the EBT system is capable of providing a transaction history for a period... with §§ 278.1 and 278.2(g) of this chapter. (iii) Residents of shelters for battered women and children...

  7. 7 CFR 274.7 - Benefit redemption by eligible households.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... State agency shall ensure that the EBT system is capable of providing a transaction history for a period... with §§ 278.1 and 278.2(g) of this chapter. (iii) Residents of shelters for battered women and children...

  8. 21 CFR 558.274 - Hygromycin B.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... methylene disalicylate or zinc bacitracin; withdraw 3 days before slaughter Bacitracin plus penicillin (100...% of penicillin plus not less than 50% of bacitracin; as procaine penicillin plus bacitracin methylene... penicillin; as procaine penicillin plus zinc bacitracin; withdraw 3 days before slaughter 3. Chickens...

  9. 21 CFR 558.274 - Hygromycin B.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... methylene disalicylate or zinc bacitracin; withdraw 3 days before slaughter Bacitracin plus penicillin (100...% of penicillin plus not less than 50% of bacitracin; as procaine penicillin plus bacitracin methylene... penicillin; as procaine penicillin plus zinc bacitracin; withdraw 3 days before slaughter 3. Chickens...

  10. 75 FR 38871 - Proposed Collection; Comment Request for Revenue Procedure 2004-29

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... comments concerning Revenue Procedure 2004-29, Statistical Sampling in Sec. 274 Context. DATES: Written... Internet, at [email protected] . SUPPLEMENTARY INFORMATION: Title: Statistical Sampling in Sec...: Revenue Procedure 2004-29 prescribes the statistical sampling methodology by which taxpayers under...

  11. Photonic Crystals on the Wing

    DTIC Science & Technology

    2011-11-01

    Giraldo MA Stavenga DG (2007) Sexual dichroism and pigment localization in the wing scales of Pieris rapae butterflies. Proc R Soc B 274:97-102 4...723 41. Stavenga DG, Arikawa K (2011) Photoreceptor spectral sensitivities of the Small White butterfly Pieris rapae crucivora interpreted with

  12. 40 CFR 421.56 - Pretreatment standards for new sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Electrolytic Copper.... The mass of wastewater pollutants in primary electrolytic copper refining process wastewater... pounds) of copper cast Arsenic .692 .309 Copper .638 .304 Nickel .274 .184 (b) Subpart E—Anode and...

  13. 40 CFR 421.56 - Pretreatment standards for new sources.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Electrolytic Copper.... The mass of wastewater pollutants in primary electrolytic copper refining process wastewater... pounds) of copper cast Arsenic .692 .309 Copper .638 .304 Nickel .274 .184 (b) Subpart E—Anode and...

  14. 75 FR 26301 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... Marvell Technology Group 273 EP El Paso Corp. Ltd. 215 XLP Consumer Staples Select 274 SEED Origin... 279 DHI DR Horton Inc. 223 WMB Williams Cos Inc/The..... 280 ADBE Adobe Systems Inc. 225 MEE Massey...

  15. 75 FR 26310 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... 273 EP El Paso Corp. Group Ltd. 215 XLP Consumer Staples 274 SEED Origin Agritech Select Sector SPDR.... 223 WMB Williams Cos Inc/The. 280 ADBE Adobe Systems Inc. 225 MEE Massey Energy Co. 281 PCX Patriot...

  16. Cyber Infrastructure Protection

    DTIC Science & Technology

    2011-05-01

    274 TOWARD A SOLUTION THAT WORKS Building on our long history of involvement in assuring all types of communications networks, Tel- cordia has...wireless, and security areas. He currently has responsibility for a new Tel- cordia software product in IP network management, and has led all product

  17. 26 CFR 1.274-5A - Substantiation requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Any activity which is of a type generally considered to constitute entertainment, amusement, or... the evidence indicated a taxpayer incurred deductible travel or entertainment expense but the exact... section, the term entertainment means entertainment, amusement, or recreation, and use of a facility...

  18. 26 CFR 1.274-5A - Substantiation requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Any activity which is of a type generally considered to constitute entertainment, amusement, or... the evidence indicated a taxpayer incurred deductible travel or entertainment expense but the exact... section, the term entertainment means entertainment, amusement, or recreation, and use of a facility...

  19. 26 CFR 1.274-5A - Substantiation requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Any activity which is of a type generally considered to constitute entertainment, amusement, or... the evidence indicated a taxpayer incurred deductible travel or entertainment expense but the exact... section, the term entertainment means entertainment, amusement, or recreation, and use of a facility...

  20. 48 CFR 211.274-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... delivered to DoD that will enhance logistics, contracting, and financial business transactions supporting... on leading practices and embraces open standards, DoD can— (a) Achieve lower life-cycle cost of item management and improve life-cycle property management; (b) Improve operational readiness; (c) Provide...

  1. ATRX binds to atypical chromatin domains at the 3′ exons of zinc finger genes to preserve H3K9me3 enrichment

    PubMed Central

    Chowdhury, Asif H.; Hasson, Dan; Dyer, Michael A.

    2016-01-01

    ABSTRACT ATRX is a SWI/SNF chromatin remodeler proposed to govern genomic stability through the regulation of repetitive sequences, such as rDNA, retrotransposons, and pericentromeric and telomeric repeats. However, few direct ATRX target genes have been identified and high-throughput genomic approaches are currently lacking for ATRX. Here we present a comprehensive ChIP-sequencing study of ATRX in multiple human cell lines, in which we identify the 3′ exons of zinc finger genes (ZNFs) as a new class of ATRX targets. These 3′ exonic regions encode the zinc finger motifs, which can range from 1–40 copies per ZNF gene and share large stretches of sequence similarity. These regions often contain an atypical chromatin signature: they are transcriptionally active, contain high levels of H3K36me3, and are paradoxically enriched in H3K9me3. We find that these ZNF 3′ exons are co-occupied by SETDB1, TRIM28, and ZNF274, which form a complex with ATRX. CRISPR/Cas9-mediated loss-of-function studies demonstrate (i) a reduction of H3K9me3 at the ZNF 3′ exons in the absence of ATRX and ZNF274 and, (ii) H3K9me3 levels at atypical chromatin regions are particularly sensitive to ATRX loss compared to other H3K9me3-occupied regions. As a consequence of ATRX or ZNF274 depletion, cells with reduced levels of H3K9me3 show increased levels of DNA damage, suggesting that ATRX binds to the 3′ exons of ZNFs to maintain their genomic stability through preservation of H3K9me3. PMID:27029610

  2. Viable phenotype of ILNEB syndrome without nephrotic impairment in siblings heterozygous for unreported integrin alpha3 mutations.

    PubMed

    Colombo, Elisa Adele; Spaccini, Luigina; Volpi, Ludovica; Negri, Gloria; Cittaro, Davide; Lazarevic, Dejan; Zirpoli, Salvatore; Farolfi, Andrea; Gervasini, Cristina; Cubellis, Maria Vittoria; Larizza, Lidia

    2016-10-07

    Integrin α3 (ITGA3) gene mutations are associated with Interstitial Lung disease, Nephrotic syndrome and Epidermolysis bullosa (ILNEB syndrome). To date only six patients are reported: all carried homozygous ITGA3 mutations and presented a dramatically severe phenotype leading to death before age 2 years, from multi-organ failure due to interstitial lung disease and congenital nephrotic syndrome. The involvement of skin and cutaneous adnexa was variable with sparse hair and nail dysplasia combined or not to skin lesions ranging from skin fragility to epidermolysis bullosa-like blistering. We report on two siblings of 13 and 9 years born to non-consanguineous healthy parents, who display growth delay, severe pulmonary fibrosis with fatigue, dyspnea on exertion and wheezing, atrophic skin with erythematosus lesions, rare eyelashes/eyebrows and pachyonychia. By exome sequencing, we identified two unreported ITGA3 missense mutations, c.373G>A (p.(G125R)) in exon 3 and c.821G>A (p.(R274Q)) in exon 6, affecting highly conserved residues in the integrin α3 extracellular N-terminal β-propeller domain. Homology modelling of α3β1 heterodimer fragment, encompassing the mutation sites, showed that G125 plays a pivotal structural role in the β-propeller, while R274 might prevent the interaction between integrin and urokinase complex. We report a variant of ILNEB syndrome in two siblings differing from the previously reported patients in the lack of nephrotic impairment and survival beyond childhood. Our siblings are the first reported compound heterozygous for ITGA3 mutations; this state as well as the hypomorphic nature of their p.(R274Q) mutation likely account for their survival.

  3. Prospective Validation of Optimal Drain Management "The 3 × 3 Rule" after Liver Resection.

    PubMed

    Mitsuka, Yusuke; Yamazaki, Shintaro; Yoshida, Nao; Masamichi, Moriguchi; Higaki, Tokio; Takayama, Tadatoshi

    2016-09-01

    We previously established an optimal postoperative drain management rule after liver resection (i.e., drain removal on postoperative day 3 if the drain fluid bilirubin concentration is <3 mg/dl) from the results of 514 drains of 316 consecutive patients. This test set predicts that 274 of 316 patients (87.0 %) will be safely managed without adverse events when drain management is performed without deviation from the rule. To validate the feasibility of our rule in recent time period. The data from 493 drains of 274 consecutive patients were prospectively collected. Drain fluid volumes, bilirubin levels, and bacteriological cultures were measured on postoperative days (POD) 1, 3, 5, and 7. The drains were removed according to the management rule. The achievement rate of the rule, postoperative adverse events, hospital stay, medical costs, and predictive value for reoperation according to the rule were validated. The rule was achieved in 255 of 274 (93.1 %) patients. The drain removal time was significantly shorter [3 days (1-30) vs. 7 (2-105), p < 0.01], drain fluid infection was less frequent [4 patients (1.5 %) vs. 58 (18.4 %), p < 0.01], postoperative hospital stay was shorter [11 days (6-73) vs. 16 (9-59), p = 0.04], and medical costs were decreased [1453 USD (968-6859) vs. 1847 (4667-9498), p < 0.01] in the validation set compared with the test set. Five patients who required reoperation were predicted by the drain-based information and treated within 2 days after operation. Our 3 × 3 rule is clinically feasible and allows for the early removal of the drain tube with minimum infection risk after liver resection.

  4. Novel antibody binding determinants on the capsid surface of serotype O foot-and-mouth disease virus

    PubMed Central

    Asfor, Amin S.; Upadhyaya, Sasmita; Knowles, Nick J.; King, Donald P.; Paton, David J.

    2014-01-01

    Five neutralizing antigenic sites have been described for serotype O foot-and-mouth disease viruses (FMDV) based on monoclonal antibody (mAb) escape mutant studies. However, a mutant virus selected to escape neutralization of mAb binding at all five sites was previously shown to confer complete cross-protection with the parental virus in guinea pig challenge studies, suggesting that amino acid residues outside the mAb binding sites contribute to antibody-mediated in vivo neutralization of FMDV. Comparison of the ability of bovine antisera to neutralize a panel of serotype O FMDV identified three novel putative sites at VP2-74, VP2-191 and VP3-85, where amino acid substitutions correlated with changes in sero-reactivity. The impact of these positions was tested using site-directed mutagenesis to effect substitutions at critical amino acid residues within an infectious copy of FMDV O1 Kaufbeuren (O1K). Recovered viruses containing additional mutations at VP2-74 and VP2-191 exhibited greater resistance to neutralization with both O1K guinea pig and O BFS bovine antisera than a virus that was engineered to include only mutations at the five known antigenic sites. The changes at VP2-74 and VP3-85 are adjacent to critical amino acids that define antigenic sites 2 and 4, respectively. However VP2-191 (17 Å away from VP2-72), located at the threefold axis and more distant from previously identified antigenic sites, exhibited the most profound effect. These findings extend our knowledge of the surface features of the FMDV capsid known to elicit neutralizing antibodies, and will improve our strategies for vaccine strain selection and rational vaccine design. PMID:24584474

  5. An updated distribution and hosts: trombiculid mites (Acari: Trombidiformes) associated with small mammals in Yunnan Province, southwest China.

    PubMed

    Peng, Pei-Ying; Guo, Xian-Guo; Ren, Tian-Guang; Dong, Wen-Ge; Song, Wen-Yu

    2016-05-01

    Trombiculid mites (or chigger mites) are a large group of arthropods, and some of these species are vectors of Orientia tsutsugamushi, the causative agent of tsutsugamushi disease (scrub typhus). Yunnan Province is situated in the southwest of China, and its complicated topography, special altitude gradients, and high biodiversity have aroused the interest of many scientists to study the fauna and species diversity of plants and animals. To replenish our former faunal study, this paper listed all the scientific names of trombiculid mites in Yunnan Province, together with their hosts and collection sites (geographical distribution). A total of 120,138 individuals of trombiculid mites were collected from the body surface of 13,760 small mammal hosts (89.06 % of them are rodents) in 29 collection sites (counties) of Yunnan Province from 2001 to 2013. The 120,138 mites were identified as comprising 2 families (Trombiculidae and Leeuwenhoekiidae), 26 genera, and 274 species. The genus Leptotrombidium had the most abundant species (109 species) of 26 genera. Of the six main vectors of scrub typhus in China, five of them were found in Yunnan. Of the 274 chigger mite species, 23 were determined as the newly recorded species (new records), which were found in Yunnan Province for the first time. The identified 274 species of trombiculid mites in the present paper are much more than those from other provinces in China and even largely exceeded the species of trombiculid mites recorded from some other regions and countries in the world. Based on the formula of Chao 1, the total number of chigger mite species in Yunnan was approximately estimated to be 346 species, and about 72 species might have been missed in our sampling process.

  6. 75 FR 39055 - Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ... Section 274(b) of the Atomic Energy Act, are utilized in part by the NRC in preparing responses to... policy development. A copy of the final supporting statement may be viewed free of charge at the NRC...

  7. 48 CFR 211.274-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... on leading practices and embraces open standards, DoD can— (a) Achieve lower life-cycle cost of item management and improve life-cycle property management; (b) Improve operational readiness; (c) Provide reliable accountability of property and asset visibility throughout the life cycle; and (d) Reduce the...

  8. 48 CFR 211.274-1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... on leading practices and embraces open standards, DoD can— (a) Achieve lower life-cycle cost of item management and improve life-cycle property management; (b) Improve operational readiness; (c) Provide reliable accountability of property and asset visibility throughout the life cycle; and (d) Reduce the...

  9. 48 CFR 211.274-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... on leading practices and embraces open standards, DoD can— (a) Achieve lower life-cycle cost of item management and improve life-cycle property management; (b) Improve operational readiness; (c) Provide reliable accountability of property and asset visibility throughout the life cycle; and (d) Reduce the...

  10. 75 FR 81601 - North American Electric Reliability Corporation; Notice of Compliance Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... Electric Reliability Corporation; Notice of Compliance Filing December 20, 2010. Take notice that on December 1, 2010, North American Electric Reliability Corporation, in response to Paragraph 274 of the... Transfer Capability Reliability Standards. \\1\\ Mandatory Reliability Standards for the Calculation of...

  11. 10 CFR 70.4 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... provides oversight and control of design information, safety information, and records of modifications... effective agreement under subsection 274b. of the Act. Non-agreement State means any other State. Alert... and borrow areas; (4) Erection of fences and other access control measures that are not related to the...

  12. 78 FR 63573 - Endangered and Threatened Wildlife and Plants; Threatened Status for Dakota Skipper and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... Swengel 1999, pp. 274, 283). The Dakota skipper flight period in a locality lasts two to four weeks, and... four Dakota skipper sites we consider the species to be present with the most recent record from 2001...

  13. 7 CFR 274.3 - Issuance systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... processing and information retrieval system and to be presented by, and returned to, recipients at retail... in a manner compatible with its system used for maintaining case record information and shall separate the information on the master issuance file into active and inactive case file categories. The...

  14. 41 CFR 101-27.403 - General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true General. 101-27.403 Section 101-27.403 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 27-INVENTORY MANAGEMENT 27.4-Elimination of...

  15. 40 CFR 52.274 - California air pollution emergency plan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... reschedule programs which require outdoor physical activity. (iv) The Administrator shall request the public... SCAQMD. (2) The owner or operator of any governmental, industrial, business, or commercial activity...) Public officials; (ii) persons operating any facility or activity named in paragraph (d)(8) of this...

  16. 7 CFR 274.3 - Retailer management.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... retailer, and it must include acceptable privacy and security features. Such systems shall only be... terminals that are capable of relaying electronic transactions to a central database computer for... specifications prior to implementation of the EBT system to enable third party processors to access the database...

  17. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... omission by the contractor that results in compromise of classified information, illegal technology... information technology services, equipment or property damage from vandalism greater than $250,000, or theft... negotiated estimated cost of the contract. This estimated cost may include the value of undefinitized change...

  18. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... omission by the contractor that results in compromise of classified information, illegal technology... information technology services, equipment or property damage from vandalism greater than $250,000, or theft... negotiated estimated cost of the contract. This estimated cost may include the value of undefinitized change...

  19. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... omission by the contractor that results in compromise of classified information, illegal technology... information technology services, equipment or property damage from vandalism greater than $250,000, or theft... negotiated estimated cost of the contract. This estimated cost may include the value of undefinitized change...

  20. 30 CFR 27.4 - Application procedures and requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... applicable MSHA product approval requirements; (iii) Identification of components or features of the product that are critical to the safety of the product; and (iv) All documentation, including drawings and... all components and subassemblies that are submitted for investigation, and shall include wiring and...

  1. 30 CFR 27.4 - Application procedures and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... applicable MSHA product approval requirements; (iii) Identification of components or features of the product that are critical to the safety of the product; and (iv) All documentation, including drawings and... all components and subassemblies that are submitted for investigation, and shall include wiring and...

  2. 7 CFR 274.4 - Reconciliation and reporting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... posted to household accounts on the central computer against benefits on the Issuance Authorization File... posting to POS transactions at retailers through settlement of retailer credits. (b) Management reports... FNS to the FNS Account Management Agent as the benefits become available to recipients. This data will...

  3. 7 CFR 274.1 - Issuance system approval standards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... computer database and electronically accessed by households at the point of sale via reusable plastic cards... submission of advance planning documents (APDs). (1) Pilot project approval requirements. To the extent the State is moving EBT to new technology or incorporating enhancements or upgrades that significantly...

  4. 10 CFR 150.20 - Recognition of Agreement State licenses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 150.20 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXEMPTIONS AND CONTINUED REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Reciprocity § 150.20 Recognition of... office for directing the licensed activity and retaining radiation safety records, is granted a general...

  5. 10 CFR 150.20 - Recognition of Agreement State licenses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 150.20 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXEMPTIONS AND CONTINUED REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Reciprocity § 150.20 Recognition of... office for directing the licensed activity and retaining radiation safety records, is granted a general...

  6. 10 CFR 150.4 - Communications.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Communications. 150.4 Section 150.4 Energy NUCLEAR... OFFSHORE WATERS UNDER SECTION 274 General Provisions § 150.4 Communications. Except where otherwise specified in this part, all communications and reports concerning the regulations in this part should be...

  7. 10 CFR 150.4 - Communications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Communications. 150.4 Section 150.4 Energy NUCLEAR... OFFSHORE WATERS UNDER SECTION 274 General Provisions § 150.4 Communications. Except where otherwise specified in this part, all communications and reports concerning the regulations in this part should be...

  8. 47 CFR 27.4 - Terms and definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS... interoperable wireless broadband network operating on the 758-763 MHz and 788-793 MHz bands and the 763-768 MHz and 793-798 MHz bands in accordance with the Commission's rules. Advanced wireless service (AWS). A...

  9. 50 CFR 216.274 - Mitigation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... safe speed. Release of ordnance through cloud cover is prohibited: aircraft must be able to actually... would be used. These aircraft would be capable of flying at the slow safe speeds necessary to enable... patrol aircraft aircrews, and Anti-submarine Warfare (ASW)/Mine Warfare (MIW) helicopter crews shall...

  10. 50 CFR 216.274 - Mitigation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... safe speed. Release of ordnance through cloud cover is prohibited: aircraft must be able to actually... would be used. These aircraft would be capable of flying at the slow safe speeds necessary to enable... patrol aircraft aircrews, and Anti-submarine Warfare (ASW)/Mine Warfare (MIW) helicopter crews shall...

  11. 50 CFR 216.274 - Mitigation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... safe speed. Release of ordnance through cloud cover is prohibited: aircraft must be able to actually... would be used. These aircraft would be capable of flying at the slow safe speeds necessary to enable... patrol aircraft aircrews, and Anti-submarine Warfare (ASW)/Mine Warfare (MIW) helicopter crews shall...

  12. 10 CFR 150.4 - Communications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Communications. 150.4 Section 150.4 Energy NUCLEAR... OFFSHORE WATERS UNDER SECTION 274 General Provisions § 150.4 Communications. Except where otherwise specified in this part, all communications and reports concerning the regulations in this part should be...

  13. 76 FR 58830 - Announcement of Funding Awards; Fair Housing Initiatives Program Fiscal Year (FY) 2008

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ....: Miami- (305) 651-4673 4 275,000.00 Gardens, FL 33169 Legal Aid Society of Palm Beach County, Inc.: 423... School: 316 South Plymouth Court, Chicago, IL (312) 982-1429 5 274,958.00 60604 Access Living of...

  14. 48 CFR 211.274-4 - Policy for reporting of Government-furnished equipment in the DoD Item Unique Identification...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... property as defined in FAR Part 45; (e) Property under any statutory leasing authority; (f) Property to... performance-based payments; (g) Intellectual property or software; and (h) Real property. [73 FR 70908, Nov...

  15. 48 CFR 211.274-4 - Policy for reporting of Government-furnished equipment in the DoD Item Unique Identification...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... property as defined in FAR Part 45; (e) Property under any statutory leasing authority; (f) Property to... performance-based payments; (g) Intellectual property or software; and (h) Real property. [73 FR 70908, Nov...

  16. 10 CFR 1.41 - Office of Federal and State Materials and Environmental Management Programs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... to the States as provided by section 274i of the Act and also to NRC staff and staff of the U.S. Navy... radioactive isotopes; (21) Oversees safe management and disposal of low-level radioactive wastes; (22) Plans...

  17. 10 CFR 1.41 - Office of Federal and State Materials and Environmental Management Programs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... to the States as provided by section 274i of the Act and also to NRC staff and staff of the U.S. Navy... radioactive isotopes; (21) Oversees safe management and disposal of low-level radioactive wastes; (22) Plans...

  18. 10 CFR 1.41 - Office of Federal and State Materials and Environmental Management Programs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to the States as provided by section 274i of the Act and also to NRC staff and staff of the U.S. Navy... radioactive isotopes; (21) Oversees safe management and disposal of low-level radioactive wastes; (22) Plans...

  19. 10 CFR 1.41 - Office of Federal and State Materials and Environmental Management Programs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... to the States as provided by section 274i of the Act and also to NRC staff and staff of the U.S. Navy... radioactive isotopes; (21) Oversees safe management and disposal of low-level radioactive wastes; (22) Plans...

  20. 10 CFR 1.41 - Office of Federal and State Materials and Environmental Management Programs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... to the States as provided by section 274i of the Act and also to NRC staff and staff of the U.S. Navy... radioactive isotopes; (21) Oversees safe management and disposal of low-level radioactive wastes; (22) Plans...

  1. Intelligent Tutoring Systems: A Taxonomy of Evaluation Issues

    DTIC Science & Technology

    1990-05-01

    teacher interaction may change (Zimmerman, Smith, Bastone , & Friend, 1989). In addition to adjusting to changing roles, the teacher must be able to...pp. 263-274). San Diego, CA: Academic Press. Zimmerman, B.J., Smith, C.P., Bastone , L, & Friend, R. (March, 1989). Socialprocesses in microcomputer

  2. 7 CFR 274.1 - Issuance system approval standards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... computer database and electronically accessed by households at the point of sale via reusable plastic cards... submission of advance planning documents (APDs). (1) Pilot project approval requirements. To the extent the State is moving EBT to new technology or incorporating enhancements or upgrades that significantly...

  3. 7 CFR 274.1 - Issuance system approval standards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... computer database and electronically accessed by households at the point of sale via reusable plastic cards... submission of advance planning documents (APDs). (1) Pilot project approval requirements. To the extent the State is moving EBT to new technology or incorporating enhancements or upgrades that significantly...

  4. 7 CFR 274.1 - Issuance system approval standards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... computer database and electronically accessed by households at the point of sale via reusable plastic cards... submission of advance planning documents (APDs). (1) Pilot project approval requirements. To the extent the State is moving EBT to new technology or incorporating enhancements or upgrades that significantly...

  5. The effects of altitude and two decongestant-antihistamine preparations on physiological functions and performance.

    DOT National Transportation Integrated Search

    1978-04-01

    Fourteen men were studied to determine the combined effects of two altitudes (ground level (1,274 ft) and 12,500 ft), and three preparations (lactose placebo, Compound A (Actifed - Registered Trade Name), and Compound B (Dristan - Registered Trade Na...

  6. 21 CFR 558.274 - Hygromycin B.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Bacitracin plus penicillin (100 to 200 of combination) 1. Chickens; control of infestation of large...) Feed containing not less than 25% of penicillin plus not less than 50% of bacitracin; as procaine penicillin plus bacitracin methylene disalicylate; withdraw 3 days before slaughter 2. Chickens; control of...

  7. 21 CFR 558.274 - Hygromycin B.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Bacitracin plus penicillin (100 to 200 of combination) 1. Chickens; control of infestation of large...) Feed containing not less than 25% of penicillin plus not less than 50% of bacitracin; as procaine penicillin plus bacitracin methylene disalicylate; withdraw 3 days before slaughter 2. Chickens; control of...

  8. 7 CFR 274.8 - Functional and technical EBT system requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... card is deactivated; (C) Communications network security that utilizes the Data Encryption Standard... PIN and/or PIN offset, to ensure data security during electronic transmission. Any of the network... household data and providing benefit and data security; (x) Inventorying and securing accountable documents...

  9. 7 CFR 274.8 - Functional and technical EBT system requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... card is deactivated; (C) Communications network security that utilizes the Data Encryption Standard... PIN and/or PIN offset, to ensure data security during electronic transmission. Any of the network... household data and providing benefit and data security; (x) Inventorying and securing accountable documents...

  10. 7 CFR 274.8 - Functional and technical EBT system requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... card is deactivated; (C) Communications network security that utilizes the Data Encryption Standard... PIN and/or PIN offset, to ensure data security during electronic transmission. Any of the network... household data and providing benefit and data security; (x) Inventorying and securing accountable documents...

  11. 7 CFR 274.8 - Functional and technical EBT system requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... card is deactivated; (C) Communications network security that utilizes the Data Encryption Standard... PIN and/or PIN offset, to ensure data security during electronic transmission. Any of the network... household data and providing benefit and data security; (x) Inventorying and securing accountable documents...

  12. Virtual Crack Extension Technique

    DTIC Science & Technology

    2008-12-01

    the Contractor and the contents do not necessarily have the approval or endorsement of Defence R& D Canada. Contract Report DRDC Atlantic CR 2008-274...the responsibility of the Contractor and the contents do not necessarily have the approval or endorsement of Defence R& D Canada. Defence R& D

  13. Effect of substituted phenylnadimides on processing and properties of PMR polyimide composites

    NASA Technical Reports Server (NTRS)

    Alston, W. B.; Lauver, R. W.

    1985-01-01

    Three nitrophenylnadimide cure initiators and two phenylnadimides (without nitros) were evaluated as additives to PMR-15 resins and Celion 6000 graphite fiber composites. The results of a resin screening study eliminated all of the additives except 3-nitrophenylnadimide (NO2PN) for use as a low temperature curing additive for PMR-15. Thus, NO2PN and the two control additives were investigated in PMR-15 formulations from which Celion 6000 graphite fiber/PMR-15 composites were processed both with low temperature (274 C) and normal (316 C) cure cycles. Comparisons of the two processing cycles, the resultant glass transition temperatures (Tg), the ambient, 274 and 316 C composite mechanical properties determined before and after 316 C postcure, the 316 C thermo-oxidative weight losses and the retention of 316 C composite mechanical properties are presented. Empirical correlations of the type and amount of nadimide additives with processing parameters, Tg, composite mechanical properties, composite thermo-oxidative stability and long term retention of 316 C composite mechanical properties are also presented.

  14. The Efficacy of an HIV Risk Reduction Intervention for Hispanic Women

    PubMed Central

    Peragallo, Nilda; McCabe, Brian E.; Cianelli, Rosina

    2012-01-01

    Culturally-specific HIV risk reduction interventions for Hispanic women are needed. SEPA (Salud/Health, Educación/Education, Promoción/Promotion, y/ and Autocuidado/Self-care) is a culturally-specific and theoretically-based group intervention for Hispanic women. The SEPA intervention consists of five sessions covering STI and HIV prevention; communication, condom negotiation and condom use; and violence prevention. A randomized trial tested the efficacy of SEPA with 548 adult U.S. Hispanic women (SEPA n = 274; delayed intervention control n = 274) who completed structured interviews at baseline and 3, 6, and 12 months post-baseline. Intent-to-treat analyses indicated that SEPA decreased positive urine samples for Chlamydia; improved condom use, decreased substance abuse and IPV; improved communication with partner, improved HIV-related knowledge, improved intentions to use condoms, decreased barriers to condom use, and increased community prevention attitudes. Culturally-specific interventions have promise for preventing HIV for Hispanic women in the U.S. The effectiveness of SEPA should be tested in a translational community trial. PMID:21969175

  15. The efficacy of an HIV risk reduction intervention for Hispanic women.

    PubMed

    Peragallo, Nilda; Gonzalez-Guarda, Rosa M; McCabe, Brian E; Cianelli, Rosina

    2012-07-01

    Culturally-specific HIV risk reduction interventions for Hispanic women are needed. SEPA (Salud/Health, Educación/Education, Promoción/Promotion, y/and Autocuidado/Self-care) is a culturally-specific and theoretically-based group intervention for Hispanic women. The SEPA intervention consists of five sessions covering STI and HIV prevention; communication, condom negotiation and condom use; and violence prevention. A randomized trial tested the efficacy of SEPA with 548 adult U.S. Hispanic women (SEPA n = 274; delayed intervention control n = 274) who completed structured interviews at baseline and 3, 6, and 12 months post-baseline. Intent-to-treat analyses indicated that SEPA decreased positive urine samples for Chlamydia; improved condom use, decreased substance abuse and IPV; improved communication with partner, improved HIV-related knowledge, improved intentions to use condoms, decreased barriers to condom use, and increased community prevention attitudes. Culturally-specific interventions have promise for preventing HIV for Hispanic women in the U.S. The effectiveness of SEPA should be tested in a translational community trial.

  16. Early-onset ocular ochronosis in a girl with alkaptonuria (AKU) and a novel mutation in homogentisate 1,2-dioxygenase (HGD).

    PubMed

    Gucev, Z S; Slaveska, N; Laban, N; Danilovski, D; Tasic, V; Pop-Jordanova, N; Zatkova, A

    2011-01-01

    Alkaptonuria (AKU) is a disorder of phenylalanine/tyrosine metabolism due to a defect in the enzyme homogentisate 1,2-dioxygenase (HGD). This recessive disease is caused by mutations in the HGD gene. We report a 14-year-old girl who was referred after presenting black urine. Careful examination revealed ochronosis of the conjunctiva. There was no affection of the cardiac valves. Elevated excretion of homogentisic acid in urine was found. Sequence analysis of the HGD gene from genomic DNA revealed that the patient is a compound heterozygote with a previously described mutation (c.473C>T, p.Pro158Leu), and a novel one (c.821C>T, p.Pro274Leu). Her mother is heterozygous for the novel mutation, while the brother is heterozygous for the previously described mutation. In summary, we describe an alkaptonuric patient with ocular ochronosis and a novel HGD mutation, c.821C>T, p.Pro274Leu.

  17. 75 FR 39586 - Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... States who have signed Agreements with NRC under Section 274b. of the Atomic Energy Act (Act)) plus one... protect public health and safety. A copy of the final supporting statement may be viewed free of charge at...

  18. 78 FR 79712 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ... Management and Budget (``OMB'') for extension and approval. Form N-8B-4 (17 CFR 274.14) is the form used by... business; investment, borrowing, and lending policies, as well as other fundamental policies; securities issued by the company; investment adviser; depositaries; management personnel; compensation paid to...

  19. 26 CFR 1.274-5A - Substantiation requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...: (1) Traveling away from home (including meals and lodging) deductible under section 162 or 212, (2... the evidence indicated a taxpayer incurred deductible travel or entertainment expense but the exact... no deduction shall be allowed for any expenditure for travel, entertainment, or a gift unless the...

  20. 7 CFR 274.2 - Providing benefits to participants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... throughout the month, or for a shorter period. When staggering benefit delivery, however, State agencies... household participating longer than two consecutive, complete months. Regardless of the issuance schedule... resumes through the end of the month or over a five-day period following the resumption of issuance, even...

  1. 7 CFR 274.2 - Providing benefits to participants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... throughout the month, or for a shorter period. When staggering benefit delivery, however, State agencies... household participating longer than two consecutive, complete months. Regardless of the issuance schedule... resumes through the end of the month or over a five-day period following the resumption of issuance, even...

  2. 7 CFR 274.2 - Providing benefits to participants.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... throughout the month, or for a shorter period. When staggering benefit delivery, however, State agencies... household participating longer than two consecutive, complete months. Regardless of the issuance schedule... resumes through the end of the month or over a five-day period following the resumption of issuance, even...

  3. 41 CFR 101-27.406 - Disposition of stock.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Disposition of stock. 101-27.406 Section 101-27.406 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 27-INVENTORY MANAGEMENT 27.4...

  4. Professionalism Among Criminal Justice Educators.

    ERIC Educational Resources Information Center

    Regoli, Robert M.; Miracle, Andrew W., Jr.

    Professionalism and its relationship to scholarly productivity was studied. Specific areas of analysis were the degree of professionalism of criminal justice educators, rankings of a series of selected publications, and the relationship between professionalism level and journal productivity. Data were derived from responses by 1,028 of 1,274…

  5. 78 FR 79567 - Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ... DEPARTMENT OF AGRICULTURE Food and Nutrition Service 7 CFR Parts 271 and 274 RIN 0584-AE26 Supplemental Nutrition Assistance Program: Trafficking Controls and Fraud Investigations AGENCY: Food and Nutrition Service, USDA. ACTION: Final rule, Interim final rule; notice of approval of Information...

  6. Detecting Planar Surfaces in Outdoor Urban Environments

    DTIC Science & Technology

    2008-09-01

    coplanar or parallel scene points and lines. Sturm and Maybank (18) perform 3D reconstruction given user-provided coplanarity, perpendicularity, and... Maybank , S. J. A method for intactive 3d reconstruction of piercewise planar objects from single images. in BMVC, 1999, 265–274 [19] Schaffalitzky, F

  7. 41 CFR 101-27.404 - Review of items.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Review of items. 101-27.404 Section 101-27.404 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 27-INVENTORY MANAGEMENT 27.4...

  8. ASTRONAUTICS INFORMATION. OPEN LITERATURE SURVEY, VOL. IV, NO. 3, ENTRIES 40,454-40,728

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carringer, E.M.; Hoppe, M.G.; Nichols, B.H. comps.

    1961-09-01

    An open literature survey dealing with astronautics covering the period of September 1961 is presented. A compilation was made of 274 references on space flight and applicable data and techniques. Author, subject, and periodical indexes are included. (M.C.G.)

  9. 40 CFR 52.274 - California air pollution emergency plan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false California air pollution emergency plan... pollution emergency plan. (a) Since the California Air Pollution Emergency Plan does not provide complete... District (SCAQMD). (2) Sacramento County Air Pollution Control District. (3) Monterey Bay Unified APCD...

  10. 40 CFR 52.274 - California air pollution emergency plan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false California air pollution emergency plan... pollution emergency plan. (a) Since the California Air Pollution Emergency Plan does not provide complete... District (SCAQMD). (2) Sacramento County Air Pollution Control District. (3) Monterey Bay Unified APCD...

  11. 40 CFR 52.274 - California air pollution emergency plan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false California air pollution emergency plan... pollution emergency plan. (a) Since the California Air Pollution Emergency Plan does not provide complete... District (SCAQMD). (2) Sacramento County Air Pollution Control District. (3) Monterey Bay Unified APCD...

  12. 76 FR 54819 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... (``mutual funds''), unit investment trusts (``UITs'') or face-amount certificate companies (collectively, ``funds'') deemed to have registered an indefinite amount of securities to file, not later than 90 days... 274.24) with the Commission. Form 24F-2 is the annual notice of securities sold by funds that...

  13. 75 FR 26299 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... Kinross Gold Corp. 273 EP El Paso Corp. 274 SEED Origin Agritech Ltd. 275 WIN Windstream Corp. 279 DHI DR Horton Inc. 280 ADBE Adobe Systems Inc. 281 PCX Patriot Coal Corp. 282 SPWRA SunPower Corp. 284 LCC US...

  14. 75 FR 26312 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... Gold Corp. 213 MRVL Marvell Technology 273 EP El Paso Corp. Group Ltd. 215 XLP Consumer Staples 274.... 220 DTV DIRECTV. 279 DHI DR Horton Inc. 223 WMB Williams Cos Inc/The. 280 ADBE Adobe Systems Inc. 225...

  15. 7 CFR 274.4 - Reconciliation and reporting.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... basis and consist of: (1) Information on how the system operates relative to its performance standards..., shall be submitted by each State agency operating an issuance system. The report shall be prepared at... reconciliation process. The EBT system shall provide reports and documentation pertaining to the following: (1...

  16. Exploring Resource Sharing between Secondary School Teachers of Agriculture and Science Departments Nationally.

    ERIC Educational Resources Information Center

    Dormody, Thomas J.

    1992-01-01

    A survey of 372 secondary agriculture teachers received 274 responses showing a majority of agriculture and science departments share resources, although at low levels. Many more predicted future sharing. Equipment and supplies were most often shared, instructional services least often. (SK)

  17. 10 CFR 150.10 - Persons exempt.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Persons exempt. 150.10 Section 150.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXEMPTIONS AND CONTINUED REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Exemptions in Agreement States § 150.10 Persons exempt. Except as...

  18. 10 CFR 150.10 - Persons exempt.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Persons exempt. 150.10 Section 150.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXEMPTIONS AND CONTINUED REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Exemptions in Agreement States § 150.10 Persons exempt. Except as...

  19. 10 CFR 150.10 - Persons exempt.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Persons exempt. 150.10 Section 150.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXEMPTIONS AND CONTINUED REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Exemptions in Agreement States § 150.10 Persons exempt. Except as...

  20. 10 CFR 150.10 - Persons exempt.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Persons exempt. 150.10 Section 150.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXEMPTIONS AND CONTINUED REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Exemptions in Agreement States § 150.10 Persons exempt. Except as...

  1. 38 CFR 21.274 - Revolving fund loan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C. Chapter 31...-interest loan from the revolving fund. (c) Eligibility. A veteran is eligible for an advance if the... section are met, a counseling psychologist or vocational rehabilitation specialist in the VR&E Division...

  2. Plain Writing Act of 2009

    THOMAS, 111th Congress

    Sen. Akaka, Daniel K. [D-HI

    2009-03-11

    Senate - 12/09/2009 Placed on Senate Legislative Calendar under General Orders. Calendar No. 222. (All Actions) Notes: For further action, see H.R.946, which became Public Law 111-274 on 10/13/2010. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  3. 26 CFR 1.274-2 - Disallowance of deductions for certain expenses for entertainment, amusement, recreation, or travel.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... such as commuting to and from work. On the other hand, the providing of a hotel room or an automobile... considered to be in a clear business setting. Also, entertainment which has the principal effect of a price...

  4. 26 CFR 1.274-2 - Disallowance of deductions for certain expenses for entertainment, amusement, recreation, or travel.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... such as commuting to and from work. On the other hand, the providing of a hotel room or an automobile... considered to be in a clear business setting. Also, entertainment which has the principal effect of a price...

  5. 26 CFR 1.274-2 - Disallowance of deductions for certain expenses for entertainment, amusement, recreation, or travel.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... such as commuting to and from work. On the other hand, the providing of a hotel room or an automobile... considered to be in a clear business setting. Also, entertainment which has the principal effect of a price...

  6. 26 CFR 1.274-2 - Disallowance of deductions for certain expenses for entertainment, amusement, recreation, or travel.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... such as commuting to and from work. On the other hand, the providing of a hotel room or an automobile... considered to be in a clear business setting. Also, entertainment which has the principal effect of a price...

  7. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... factor, if used, must include consideration of risk management (including mission success, safety... above the contracting officer, with the concurrence of the project manager. The rationale for any waiver shall be documented in the contract file. When safety, export control, or security are considered under...

  8. 40 CFR 52.274 - California air pollution emergency plan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false California air pollution emergency plan... pollution emergency plan. (a) Since the California Air Pollution Emergency Plan does not provide complete... District (SCAQMD). (2) Sacramento County Air Pollution Control District. (3) Monterey Bay Unified APCD...

  9. Additional Guidance and Training Needed to Improve Afghan National Army Pharmaceutical Distribution

    DTIC Science & Technology

    2012-05-07

    capacity for Afghan-led security. To help accomplish part of that mission, CSTC-A provided oversight and mentoring of the ANA pharmaceutical...National Military Hospital Ketamine 4575 4755 180 Tramadol 1650 1700 50 Insulin-Regular 274 280 6 Mebendazol 1164 1100 (64

  10. 5 CFR 890.102 - Coverage.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Coverage. 890.102 Section 890.102... EMPLOYEES HEALTH BENEFITS PROGRAM Administration and General Provisions § 890.102 Coverage. (a) Each.... L. 105-274 (112 Stat. 2419). (d) Paragraph (c) of this section does not deny coverage to: (1) An...

  11. Rapid Evolution of the Solar Atmosphere During the Impulsive Phase of a Microflare Observed with Hinode's EIS: Hints of Chromospheric Magnetic Reconnection

    NASA Astrophysics Data System (ADS)

    Brosius, J. W.

    2013-12-01

    We obtained rapid cadence (11.2 s) EUV stare spectra of a solar microflare with the Extreme-ultraviolet Imaging Spectrometer (EIS) aboard Hinode. The intensities of lines formed at temperatures too cool to be found in the corona brightened by factors around 16 early during this event, indicating that energy must be deposited in the chromosphere. The flare started earlier in its transition region emission than it did in its hottest emission, which rules out thermal conduction from a directly heated coronal source as the means of energy transport to the chromosphere. All of the lines showed an increase in nonthermal turbulent velocity by factors of about 3 during the flare. None of the lines exhibited systematic, significant upflows starting at flare onset. We derive the density evolution of the flare plasma at temperature around 2 MK from the intensity ratio of Fe XIV lines at 264.789 and 274.204 A. From both lines we removed the bright pre-flare quiescent emission, and from 274.204 we removed the blended emission of Si VII 274.180 based on the Si VII 274.180/275.361 intensity ratio, which varies only slightly with density. In this way the flare electron density is derived with emission from only the flare plasma. The density increased by an order of magnitude from its pre-flare quiescent average of 3.43+/-0.19 x 10^9 /cm^3 to its maximum impulsive phase value of 3.04+/-0.57 x 10^10 /cm^3 in 2 minutes. The fact that this rapid increase in density is not accompanied by systematic, large upward velocities indicates that the density increase is not due to the filling of loops with evaporated chromospheric material, but rather due to material being directly heated in the chromosphere, likely by magnetic reconnection. The density increase may be due to a progression of reconnection sites to greater depths in the chromosphere, where it has access to larger densities, or it may be due to compression of 2 MK plasma by the 10 MK plasma as it attempts to expand against the high density chromospheric plasma. The further absence of flows during the cooling phase indicates that flare plasma was not falling down (draining from heated, filled loops), but cooling locally in the chromosphere. This work was supported by NASA grant NNX10AC08G.

  12. 7 CFR 274.2 - Providing benefits to participants.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., households being moved into or out of a staggered issuance procedure, households on a fluctuating schedule within a staggered system, and households being moved from a direct-mail issuance system to an... issuances, the State agency shall divide the new issuance into two parts, with one part being issued within...

  13. 26 CFR 1.274-5A - Substantiation requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... independent contractor to his client or customer in the regular course of good business practice. (b... nature occurring during the course of a single event shall be considered a single expenditure. To... the portion of such amount which is attributable to each person participating in the event giving rise...

  14. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Contractor that consists of an accident, incident, or exposure resulting in a fatality or mission failure; or in damage to equipment or property equal to or greater than $1 million; or in any “willful” or... (including mission success, safety, security, health, export control, and damage to the environment, as...

  15. 26 CFR 1.274-5T - Substantiation requirements (temporary).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... or credit shall be allowed with respect to— (1) Traveling away from home (including meals and lodging... Cir. 1930). The decision held that, where the evidence indicated a taxpayer incurred deductible travel...) and this section contemplate that no deduction or credit shall be allowed for travel, entertainment, a...

  16. 43 CFR 2.74 - Petitions for amendment: Appeals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Assistant Secretary—Policy, Budget and Administration. (b) Time for appeal. (1) An appeal must be received no later than twenty (20) working days after the date of the decision on a petition. (2) The Assistant Secretary—Policy, Budget and Administration may, for good cause shown, extend the time for...

  17. 10 CFR 76.4 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... to the Act. Administrative controls means the provisions relating to organization and management... agreement under subsection 274b. of the Act. Non-Agreement State means any other State. Alert means events... equivalent means the sum of the products of the dose equivalent to the body organ or tissue and the weighting...

  18. 10 CFR 76.4 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... to the Act. Administrative controls means the provisions relating to organization and management... agreement under subsection 274b. of the Act. Non-Agreement State means any other State. Alert means events... equivalent means the sum of the products of the dose equivalent to the body organ or tissue and the weighting...

  19. 10 CFR 76.4 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... to the Act. Administrative controls means the provisions relating to organization and management... agreement under subsection 274b. of the Act. Non-Agreement State means any other State. Alert means events... equivalent means the sum of the products of the dose equivalent to the body organ or tissue and the weighting...

  20. 10 CFR 76.4 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... to the Act. Administrative controls means the provisions relating to organization and management... agreement under subsection 274b. of the Act. Non-Agreement State means any other State. Alert means events... equivalent means the sum of the products of the dose equivalent to the body organ or tissue and the weighting...

  1. 10 CFR 76.4 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to the Act. Administrative controls means the provisions relating to organization and management... agreement under subsection 274b. of the Act. Non-Agreement State means any other State. Alert means events... equivalent means the sum of the products of the dose equivalent to the body organ or tissue and the weighting...

  2. 10 CFR 30.4 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Commission has entered into an effective agreement under subsection 274b. of the Act. Non-agreement State... access control measures that are not related to the safe use of, or security of, radiological materials... equivalent means the sum of the products of the dose equivalent to the organ or tissue and the weighting...

  3. 7 CFR 274.2 - Providing benefits to participants.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... for both months as an aggregate (combined) allotment, or as two separate allotments, made available at... allotments. (1) State agencies may stagger issuance throughout the month, or for a shorter period. When... issuance into two parts, with one part being issued within the 40-day period, and the second part, or...

  4. 37 CFR 2.74 - Form and signature of amendment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Form and signature of... signature of amendment. (a) Form of Amendment. Amendments should be set forth clearly and completely... record. (b) Signature. A request for amendment of an application must be signed by the applicant, someone...

  5. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... immediately washed off with detergent and water. 7. Protective clothing is used in conjunction with... lightweight water and chemical resistant throw away type protective clothing that is impervious to herbicides... beneficial in reducing physical stress to applicators. Additional protection is afforded by protective skin...

  6. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... immediately washed off with detergent and water. 7. Protective clothing is used in conjunction with... lightweight water and chemical resistant throw away type protective clothing that is impervious to herbicides... beneficial in reducing physical stress to applicators. Additional protection is afforded by protective skin...

  7. Fathering and Attachment in the USA and Taiwan: Contextual Predictors and Child Outcomes

    ERIC Educational Resources Information Center

    Newland, Lisa A.; Coyl, Diana D.; Chen, Hui-Hua

    2010-01-01

    This study examined connections between fathering context (stress, social support, and fathers' internal working models), fathering dimensions, children's attachment to fathers, and children's social-emotional and academic outcomes within two culturally diverse samples in the USA and Taiwan. Participants included 274 fathers and their eight- to…

  8. Television in the Lives of the Elderly: Attitudes and Opinions.

    ERIC Educational Resources Information Center

    Davis, Richard H.; Westbrook, G. Jay

    1985-01-01

    This replication of a 1969 study surveyed audience attitudes of 274 elderly adults about television and its importance in their lives. The report focuses on the issues of television as entertainment, companionship function, influence of commercials on buying decisions, preferred programing, objectionable programing, and television's portrayal of…

  9. 8 CFR 274a.6 - State employment agencies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... this period: (i) The job order or other appropriate referral form issued by the state employment agency... the Act and the regulations issued thereunder. (ii) In the case of a telephonically authorized job... made and shall serve as evidence of the job order. The employer should retain the document containing...

  10. 26 CFR 1.274-5T - Substantiation requirements (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... which are charged directly or indirectly to the employer (for example, through credit cards) or for... directly or indirectly to the client or customer through credit card systems or otherwise. See paragraph (j... only for the driver plus a folding jump seat, (I) Dump trucks (including garbage trucks), (J) Flatbed...

  11. 17 CFR 274.13 - Form N-8B-3, registration statement of unincorporated management investment companies currently...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of unincorporated management investment companies currently issuing periodic payment plan...-8B-3, registration statement of unincorporated management investment companies currently issuing..., pursuant to section 8(b) of the Investment Company Act of 1940, by unincorporated management investment...

  12. 17 CFR 270.8b-33 - XBRL-Related Documents.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... electronic format as an exhibit to a filing on Form N-1A (§§ 239.15A and 274.11A of this chapter), Form N-CSR... separately identified. A registrant may submit such exhibit with, or in an amendment to, the Form N-CSR or...

  13. 7 CFR 274.11 - Issuance and inventory record retention, and forms security.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... processed within the State agency. The State agency shall use numbers, batching, inventory control logs, or...) Secure storage; (iii) Access limited to authorized personnel; (iv) Bulk inventory control records; (v... validation of inventory controls and records by parties not otherwise involved in maintaining control records...

  14. 76 FR 58827 - Announcement of Funding Awards; Fair Housing Initiatives Program Fiscal Year (FY) 2009

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... Street, Austin, TX (512) 474-7007 6 274,707.00 78702 San Antonio Fair Housing Council, Inc.: 4414....00 Houston, TX 77001-0292 Arizona Fair Housing Center: 615 N 5th Avenue, Phoenix, AZ 85003. (602) 548..., Cincinnati, OH 45202 [[Page 58830

  15. 75 FR 10238 - Combined Notice of Filings No. 2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ... February 4, 2010. Take notice that the Commission has received the following Natural Gas Pipeline Rate and Refund Report filings: Docket Numbers: RP04-274-022. Applicants: Kern River Gas Transmission Company...: Millennium Pipeline Co, LLC submits Substitute Second Revised Sheet No. 233 to FERC Gas Tariff, Original...

  16. 7 CFR 274.6 - Replacement issuances to households.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... recipient's signature on the authorization document matches the signature on the ID card. In a Photo ID area... matches the serial number on the recipient's ID card; (3) Issue a replacement in accordance with... other action, such as correcting the address on the master issuance file, warranted by the reported...

  17. 47 CFR 27.4 - Terms and definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... radiocommunication service licensed pursuant to this part for the frequency bands specified in § 27.5(h). Affiliate.... Assigned frequency. The center of the frequency band assigned to a station. Attended operation. Operation... frequencies permitted to be used by a station. This is normally considered to be the necessary or occupied...

  18. Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations Act, 2014

    THOMAS, 113th Congress

    Rep. Aderholt, Robert B. [R-AL-4

    2013-06-18

    House - 06/26/2013 Rule H. Res. 274 passed House. (All Actions) Notes: For further action, see H.R.3547, which became Public Law 113-76 on 1/17/2014. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  19. 7 CFR 274.8 - Responsibilities of coupon issuers, and bulk storage and claims collection points.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION...) Supporting documentation. Coupon issuers and bulk storage points shall submit to the State agency supporting... documentation shall include documents supporting coupon shipments, transfers, and issuances. In those States...

  20. 8 CFR 270.3 - Penalties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Penalties. 270.3 Section 270.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS PENALTIES FOR DOCUMENT FRAUD § 270.3 Penalties. (a) Criminal penalties. Nothing in section 274C of the Act shall be construed to diminish or...

  1. 50 CFR 216.274 - Mitigation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... properly installed and in good working order to assist in the detection of marine mammals in the vicinity...” (20x110) binoculars shall be present and in good working order to assist in the detection of marine... NMFS Office of Protected Resources Headquarters Senior Official designated in the SOCAL Range Complex...

  2. 77 FR 30998 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Government...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... of Inventory Schedules; DD Form 1639, Scrap Warranty; DD Form 1640, Request for Plant Clearance; DD... respondents, including the use of automated collection techniques or other forms of information technology... contractor inventory. a. DFARS 211.274, Item identification and valuation requirements, and the associated...

  3. 7 CFR 274.12 - Electronic Benefit Transfer issuance system approval standards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... are trained in system operation prior to implementation. Retailer training shall be offered by the... paragraph at customer service booths or other locations if appropriate. (5) The State agency shall ensure... AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ISSUANCE AND...

  4. The Critical Importance of Costs for Education Decisions. REL 2017-274

    ERIC Educational Resources Information Center

    Hollands, Fiona M.; Levin, Henry M.

    2017-01-01

    This brief provides guidance to decision makers in schools, districts, state education departments, and intermediary organizations about ways that cost analyses can help inform their decisions about program choices, budgets, and strategies. It addresses questions about: (1) why cost information matters in education; (2) what cost metrics are…

  5. Attachment, Perceived Conflict, and Couple Satisfaction: Test of a Mediational Dyadic Model

    ERIC Educational Resources Information Center

    Brassard, Audrey; Lussier, Yvan; Shaver, Phillip R.

    2009-01-01

    Attachment insecurities (anxiety and avoidance) are often associated with relationship dissatisfaction, but the mediators have been unclear. We examined the mediating role of perceived conflict in 274 French-Canadian couples who completed measures of attachment insecurities, perception of conflict, and relationship satisfaction. Partners' own…

  6. 47 CFR 27.4 - Terms and definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... product of the power supplied to the antenna and its gain relative to a half-wave dipole in a given... and the antenna gain in a given direction relative to an isotropic antenna. Fixed service. A radio... functions that could be performed at the transmitter. Satellite Digital Audio Radio Service (satellite DARS...

  7. Restoration of frictional characteristics on older Portland cement concrete pavement.

    DOT National Transportation Integrated Search

    1986-06-01

    Safety is a very important aspect o f the highway program. The Iowa DOT : initiated an inventory of the friction values of all paved primary : roadways i n 1969. This inventory, with an ASTM E-274 test unit, has : continued to the present time. The t...

  8. 40 CFR 421.274 - Standards of performance for new sources.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare Earth... Scrubber. NSPS for the Primary Rare Earth Metals Subcategory Pollutant or pollutant property Maximum for... wet rare earth chlorides Hexachlorobenzene 0.042 0.042 Chromium (total) 1.544 0.626 Lead 1.168 0.542...

  9. 40 CFR 421.274 - Standards of performance for new sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare Earth... Scrubber. NSPS for the Primary Rare Earth Metals Subcategory Pollutant or pollutant property Maximum for... wet rare earth chlorides Hexachlorobenzene 0.042 0.042 Chromium (total) 1.544 0.626 Lead 1.168 0.542...

  10. 40 CFR 421.274 - Standards of performance for new sources.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare Earth... Scrubber. NSPS for the Primary Rare Earth Metals Subcategory Pollutant or pollutant property Maximum for... wet rare earth chlorides Hexachlorobenzene 0.042 0.042 Chromium (total) 1.544 0.626 Lead 1.168 0.542...

  11. 40 CFR 421.274 - Standards of performance for new sources.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare Earth... Scrubber. NSPS for the Primary Rare Earth Metals Subcategory Pollutant or pollutant property Maximum for... wet rare earth chlorides Hexachlorobenzene 0.042 0.042 Chromium (total) 1.544 0.626 Lead 1.168 0.542...

  12. 40 CFR 421.274 - Standards of performance for new sources.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare Earth... Scrubber. NSPS for the Primary Rare Earth Metals Subcategory Pollutant or pollutant property Maximum for... wet rare earth chlorides Hexachlorobenzene 0.042 0.042 Chromium (total) 1.544 0.626 Lead 1.168 0.542...

  13. Science Teachers' Perception on Multicultural Education Literacy and Curriculum Practices

    ERIC Educational Resources Information Center

    Huang, Hsiu-Ping; Cheng, Ying-Yao; Yang, Cheng-Fu

    2017-01-01

    This study aimed to explore the current status of teachers' multicultural education literacy and multicultural curriculum practices, with a total of 274 elementary school science teachers from Taitung County as survey participants. The questionnaire used a Likert-type four-point scale which content included the teachers' perception of…

  14. 77 FR 50211 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... taxation of fringe benefits and exclusions from gross income for certain fringe Benefits, listed property...-63-88 (Final and temporary regulations) Taxation of Fringe Benefits and Exclusions From Gross Income... Code section 274(d). The regulation also provides guidance on the taxation of fringe benefits and...

  15. USAID Assistance to Afghanistan Reconstruction: $13.3 Billion Obligated Between 2002 and 2013

    DTIC Science & Technology

    2014-01-01

    Development Group 274 TAF -The Asia Foundation 157 AED-Academy for Educational Development 146 CEPPS-Consortium For Elections and Political Process...United Nations Development Program 268,825 WHO 107,337 IFDC-International Fertilizer Development Center 32,531 TAF -The Asia Foundation 24,122 DANIDA

  16. Frames of Reference and Antecedentless Anaphora in Spanish Conversation

    ERIC Educational Resources Information Center

    Blackwell, Sarah E.

    2018-01-01

    This study examines native Spanish speakers' use of anaphoric pronouns and null subjects in conversational discourse in the absence of coreferential antecedents. It also considers the adequacy of Gundel et al.'s proposal ("Language "69(2):274-307, 1993) that the cognitive status "in focus" corresponds with speakers' use of…

  17. Genetic and Epigenetic Biomarkers for Recurrent Prostate Cancer After Radiotherapy

    DTIC Science & Technology

    2015-07-01

    several distinct advantages over surgical treatment, such as no complications from surgery, and a low risk of urinary incontinence , RT treatment takes...Khorana, Tissue factor and VEGF expression in prostate carcinoma: a tissue microarray study. Cancer Invest, 2009. 27(4): p. 430-4. 7. Crawford, E.D

  18. 5 CFR 890.102 - Coverage.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Coverage. 890.102 Section 890.102... EMPLOYEES HEALTH BENEFITS PROGRAM Administration and General Provisions § 890.102 Coverage. (a) Each... by Pub. L. 105-274 (112 Stat. 2419). (d) Paragraph (c) of this section does not deny coverage to: (1...

  19. 5 CFR 890.102 - Coverage.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Coverage. 890.102 Section 890.102... EMPLOYEES HEALTH BENEFITS PROGRAM Administration and General Provisions § 890.102 Coverage. (a) Each... by Pub. L. 105-274 (112 Stat. 2419). (d) Paragraph (c) of this section does not deny coverage to: (1...

  20. An Investigation of the Relationship between Cognitive Reactivity and Rumination

    ERIC Educational Resources Information Center

    Moulds, Michelle L.; Kandris, Eva; Williams, Alishia D.; Lang, Tamara; Yap, Carol; Hoffmeister, Karolin

    2008-01-01

    Teasdale's (Teasdale, J.D. (1988). Cognitive vulnerability to persistent depression. "Cognition and Emotion," 2, 247-274) differential activation hypothesis refers to the ease with which maladaptive cognitive processes are triggered by mild dysphoria as "cognitive reactivity." Supporting this model is evidence of a differential association between…

  1. 40 CFR 761.274 - Reporting PCB concentrations in samples.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT POLYCHLORINATED BIPHENYLS (PCBs) MANUFACTURING, PROCESSING, DISTRIBUTION IN... concentrations for non-liquid PCBs on a dry weight basis as micrograms of PCBs per gram of sample (ppm by weight... quotient by the total number of micrograms of PCBs on the surface to obtain the equivalent measurement of...

  2. 40 CFR 761.274 - Reporting PCB concentrations in samples.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT POLYCHLORINATED BIPHENYLS (PCBs) MANUFACTURING, PROCESSING, DISTRIBUTION IN... concentrations for non-liquid PCBs on a dry weight basis as micrograms of PCBs per gram of sample (ppm by weight... quotient by the total number of micrograms of PCBs on the surface to obtain the equivalent measurement of...

  3. College Women's Career Self-Efficacy and Educational Environments.

    ERIC Educational Resources Information Center

    Scheye, Paula A.; Gilroy, Faith D.

    1994-01-01

    Examined relationship between composition by sex (single-sex versus coeducational) of women's (n=274) high school and college environments and sex of their selected influential teachers and their self-efficacy in traditional or nontraditional careers. Found no main effects for composition by sex of institution, or sex of influential teachers, nor…

  4. Industrialization and Household Complexity in Rural Taiwan.

    ERIC Educational Resources Information Center

    Lavely, William

    1990-01-01

    In 274 Taiwanese townships, farm household complexity in 1960 and 1970 was positively related to the proportion of the labor force in nonagricultural occupations. The close proximity of industry to family farms in Taiwan has reduced rural to urban migration usually associated with industrialization. Contains 46 references. (Author/SV)

  5. Competitive fitness of influenza B viruses with neuraminidase inhibitor-resistant substitutions in a coinfection model of the human airway epithelium.

    PubMed

    Burnham, Andrew J; Armstrong, Jianling; Lowen, Anice C; Webster, Robert G; Govorkova, Elena A

    2015-04-01

    Influenza A and B viruses are human pathogens that are regarded to cause almost equally significant disease burdens. Neuraminidase (NA) inhibitors (NAIs) are the only class of drugs available to treat influenza A and B virus infections, so the development of NAI-resistant viruses with superior fitness is a public health concern. The fitness of NAI-resistant influenza B viruses has not been widely studied. Here we examined the replicative capacity and relative fitness in normal human bronchial epithelial (NHBE) cells of recombinant influenza B/Yamanashi/166/1998 viruses containing a single amino acid substitution in NA generated by reverse genetics (rg) that is associated with NAI resistance. The replication in NHBE cells of viruses with reduced inhibition by oseltamivir (recombinant virus with the E119A mutation generated by reverse genetics [rg-E119A], rg-D198E, rg-I222T, rg-H274Y, rg-N294S, and rg-R371K, N2 numbering) or zanamivir (rg-E119A and rg-R371K) failed to be inhibited by the presence of the respective NAI. In a fluorescence-based assay, detection of rg-E119A was easily masked by the presence of NAI-susceptible virus. We coinfected NHBE cells with NAI-susceptible and -resistant viruses and used next-generation deep sequencing to reveal the order of relative fitness compared to that of recombinant wild-type (WT) virus generated by reverse genetics (rg-WT): rg-H274Y > rg-WT > rg-I222T > rg-N294S > rg-D198E > rg-E119A ≫ rg-R371K. Based on the lack of attenuated replication of rg-E119A in NHBE cells in the presence of oseltamivir or zanamivir and the fitness advantage of rg-H274Y over rg-WT, we emphasize the importance of these substitutions in the NA glycoprotein. Human infections with influenza B viruses carrying the E119A or H274Y substitution could limit the therapeutic options for those infected; the emergence of such viruses should be closely monitored. Influenza B viruses are important human respiratory pathogens contributing to a significant portion of seasonal influenza virus infections worldwide. The development of resistance to a single class of available antivirals, the neuraminidase (NA) inhibitors (NAIs), is a public health concern. Amino acid substitutions in the NA glycoprotein of influenza B virus not only can confer antiviral resistance but also can alter viral fitness. Here we used normal human bronchial epithelial (NHBE) cells, a model of the human upper respiratory tract, to examine the replicative capacities and fitness of NAI-resistant influenza B viruses. We show that virus with an E119A NA substitution can replicate efficiently in NHBE cells in the presence of oseltamivir or zanamivir and that virus with the H274Y NA substitution has a relative fitness greater than that of the wild-type NAI-susceptible virus. This study is the first to use NHBE cells to determine the fitness of NAI-resistant influenza B viruses. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  6. Burnout and Competency Development in Pre-Service Teacher Training

    ERIC Educational Resources Information Center

    Rodríguez-Hidalgo, Antonio J.; Calmaestra, Juan; Dios, Irene

    2014-01-01

    Introduction: The burnout syndrome negatively affects the students' academic performance. The relation between academic burnout and the self-perception of skills in initial teacher training is subjected to analysis. Method: A sample of 274 students (average age = 20,61 years old) from the Bachelor Degree in Early Childhood Education and the…

  7. Prevalence of Dating Violence and Victimization: Regional and Gender Differences

    ERIC Educational Resources Information Center

    Marquart, Beverly S.; Nannini, Dawn K.; Edwards, Ruth W.; Stanley, Linda R.; Wayman, Jeffrey C.

    2007-01-01

    This report examines (1) the prevalence of dating violence victimization from a national sample of rural adolescents and (2) patterns by gender and region. Analyses are based on 20,274 adolescents who reported violence victimization using the Community Drug and Alcohol Survey. The relationship of dating violence with gender and region was assessed…

  8. Candidate Pools or Puddles: Challenges and Trends in the Recruitment and Hiring of Resident Directors.

    ERIC Educational Resources Information Center

    Belch, Holley A.; Mueller, John A.

    2003-01-01

    Researchers examined the perspectives of 274 senior housing officers and 283 graduate students on the declining number of resident director candidates. Data from two separate surveys indicated that quality of life, remuneration, and interest in the residence life profession were significant issues. Implications for professional preparation,…

  9. Mother-Daughter Communication about Sex and Sexual Intercourse among Middle- to Upper-Class African American Girls

    ERIC Educational Resources Information Center

    Usher-Seriki, Kimberly K.; Bynum, Mia Smith; Callands, Tamora A.

    2008-01-01

    This study investigated linkages between various dimensions of mother-daughter communication about sex and sexual intercourse in a sample of 274 middle- to upper-income African American adolescent girls, drawn from the National Longitudinal Study of Adolescent Health. Logistic regression analysis revealed that girls who reported closer…

  10. An Analysis of the Relationship between Organizational Communication and Organizational Cynicism According to Teachers' Perceptions in Turkey

    ERIC Educational Resources Information Center

    Ayik, Ahmet

    2015-01-01

    In this study, the relations between organizational communication and organizational cynicism have been analyzed. The sample of the study consists of 274 teachers working in state secondary schools in Palandöken County of Erzurum, in 2013-2014 academic year. "Organizational Cynicism Scale" and "Organizational Communication…

  11. Engineering Gender--Gendering Engineering: What About Women in Nerd-Dom?

    ERIC Educational Resources Information Center

    Tonso, Karen L.

    This paper examines the kinds of persons that engineering education produces, focusing on cultural identities related to gender issues. It is based on survey questionnaires, interviews, and observations of 274 first-year and fourth-year engineering students at a state university known for its concern about the education of women engineers. The…

  12. Songs as an Aid for Language Acquisition

    ERIC Educational Resources Information Center

    Schon, Daniele; Boyer, Maud; Moreno, Sylvain; Besson, Mireille; Peretz, Isabelle; Kolinsky, Regine

    2008-01-01

    In previous research, Saffran and colleagues [Saffran, J. R., Aslin, R. N., & Newport, E. L. (1996). Statistical learning by 8-month-old infants. Science, 274, 1926-1928; Saffran, J. R., Newport, E. L., & Aslin, R. N. (1996). Word segmentation: The role of distributional cues. "Journal of Memory and Language," 35, 606-621.] have shown that adults…

  13. Preservice Biology Teachers' Professional Knowledge: Structure and Learning Opportunities

    ERIC Educational Resources Information Center

    Großschedl, Jörg; Harms, Ute; Kleickmann, Thilo; Glowinski, Ingrid

    2015-01-01

    What learning opportunities in higher education promote the development of content knowledge (CK), pedagogical content knowledge (PCK), and pedagogical knowledge (PK)? In order to investigate this question, a cross-sectional study with a total of 274 German preservice biology teachers (21.5% male, average age 22.8 years) was conducted in German…

  14. Attachment Style, Social Support, and Coping as Psychosocial Correlates of Happiness in Persons with Spinal Cord Injuries

    ERIC Educational Resources Information Center

    Wilson, Lisa; Catalano, Denise; Sung, Connie; Phillips, Brian; Chou, Chih-Chin; Chan, Jacob Yui Chung; Chan, Fong

    2013-01-01

    Objective: To examine the roles of attachment, social support, and coping as psychosocial correlates in predicting happiness in people with spinal cord injuries. Design: Quantitative descriptive research design using multiple regression and correlation techniques. Participants: 274 individuals with spinal cord injuries. Outcome Measures: Happiness…

  15. 76 FR 69306 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... Securities and Exchange Commission (the ``Commission'') has submitted to the Office of Management and Budget... ``Investment Company Act'') requires a registered management investment company (``fund'') to (1) file a report with the Commission on Form N-CSR (17 CFR 249.331 and 274.128) not later than 10 days after the...

  16. 17 CFR 274.128 - Form N-CSR, certified shareholder report.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-CSR, certified... Form N-CSR, certified shareholder report. This form shall be used by registered management investment... Form N-CSR, see the List of CFR Sections Affected, which appears in the Finding Aids section of the...

  17. 17 CFR 274.128 - Form N-CSR, certified shareholder report.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form N-CSR, certified... Form N-CSR, certified shareholder report. This form shall be used by registered management investment... Form N-CSR, see the List of CFR Sections Affected, which appears in the Finding Aids section of the...

  18. Eating habits among adolescents in rural Southern Appalachia.

    PubMed

    Wu, Tiejian; Stoots, James Michael; Florence, James E; Floyd, Michael R; Snider, Jeromy Blake; Ward, Ryan D

    2007-06-01

    A survey of 274 adolescents aged 14-16 years in rural Appalachia showed that unhealthy eating habits were prevalent. A few adolescents were teased about weight whereas 20.1% witnessed weight teasing almost everyday. Perception of parents' healthy eating and better social support for healthy eating were associated with healthier eating habits.

  19. The Role of Perceived Maternal Favoritism in Sibling Relations in Midlife

    ERIC Educational Resources Information Center

    Suitor, J. Jill; Sechrist, Jori; Plikuhn, Mari; Pardo, Seth T.; Gilligan, Megan; Pillemer, Karl

    2009-01-01

    Data were collected from 708 adult children nested within 274 later-life families from the Within-Family Differences Study to explore the role of perceived maternal favoritism in the quality of sibling relations in midlife. Mixed-model analyses revealed that regardless of which sibling was favored, perceptions of current favoritism and…

  20. 40 CFR 60.274 - Monitoring of operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... that is important to the performance of the total capture system (i.e., pressure sensors, dampers, and... under paragraph (d) of this section; and (4) All pressure data obtained under paragraph (f) of this... provisions of this subpart shall check and record on a once-per-shift basis furnace static pressure (if a DEC...

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