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Sample records for bornholm model set-up

  1. Setting up virgin stress conditions in discrete element models

    PubMed Central

    Rojek, J.; Karlis, G.F.; Malinowski, L.J.; Beer, G.

    2013-01-01

    In the present work, a methodology for setting up virgin stress conditions in discrete element models is proposed. The developed algorithm is applicable to discrete or coupled discrete/continuum modeling of underground excavation employing the discrete element method (DEM). Since the DEM works with contact forces rather than stresses there is a need for the conversion of pre-excavation stresses to contact forces for the DEM model. Different possibilities of setting up virgin stress conditions in the DEM model are reviewed and critically assessed. Finally, a new method to obtain a discrete element model with contact forces equivalent to given macroscopic virgin stresses is proposed. The test examples presented show that good results may be obtained regardless of the shape of the DEM domain. PMID:27087731

  2. Precision assessment of model-based RSA for a total knee prosthesis in a biplanar set-up.

    PubMed

    Trozzi, C; Kaptein, B L; Garling, E H; Shelyakova, T; Russo, A; Bragonzoni, L; Martelli, S

    2008-10-01

    Model-based Roentgen Stereophotogrammetric Analysis (RSA) was recently developed for the measurement of prosthesis micromotion. Its main advantage is that markers do not need to be attached to the implants as traditional marker-based RSA requires. Model-based RSA has only been tested in uniplanar radiographic set-ups. A biplanar set-up would theoretically facilitate the pose estimation algorithm, since radiographic projections would show more different shape features of the implants than in uniplanar images. We tested the precision of model-based RSA and compared it with that of the traditional marker-based method in a biplanar set-up. Micromotions of both tibial and femoral components were measured with both the techniques from double examinations of patients participating in a clinical study. The results showed that in the biplanar set-up model-based RSA presents a homogeneous distribution of precision for all the translation directions, but an inhomogeneous error for rotations, especially internal-external rotation presented higher errors than rotations about the transverse and sagittal axes. Model-based RSA was less precise than the marker-based method, although the differences were not significant for the translations and rotations of the tibial component, with the exception of the internal-external rotations. For both prosthesis components the precisions of model-based RSA were below 0.2 mm for all the translations, and below 0.3 degrees for rotations about transverse and sagittal axes. These values are still acceptable for clinical studies aimed at evaluating total knee prosthesis micromotion. In a biplanar set-up model-based RSA is a valid alternative to traditional marker-based RSA where marking of the prosthesis is an enormous disadvantage.

  3. Consequences of artificial deepwater ventilation in the Bornholm Basin for oxygen conditions, cod reproduction and benthic biomass - a model study

    NASA Astrophysics Data System (ADS)

    Stigebrandt, A.; Rosenberg, R.; Råman Vinnå, L.; Ödalen, M.

    2014-07-01

    We develop and use a circulation model to estimate hydrographical and ecological changes in the isolated basin water of the Bornholm Basin. By pumping well oxygenated so-called winter water, residing beneath the level of the summer thermocline, to the greatest depth of the basin, where it is forced to mix with the resident water, the rate of density reduction should increase and thereby the frequency of intrusions of new oxygen-rich deepwater. We show that pumping 1000 m3 s-1 should increase the rates of water exchange and oxygen supply by 2.5 and 3 times, respectively. The CRV (Cod Reproduction Volume), the volume of water in the isolated basin meeting the requirements for successful cod reproduction (S > 11, O2 > 2 mL L-1), should every year be greater than 54 km3, which is an immense improvement since it in certain years is currently much less. Anoxic bottoms should no longer occur in the basin and hypoxic events will become rare. This should permit extensive colonization of fauna on the earlier periodically anoxic bottoms. Increased biomass of benthic fauna should also mean increased food supply to economically valuable demersal fish like cod and flatfish. In addition, the bioturbation activity and re-oxygenation of the sediments should lead to increased phosphorus retention by the sediments.

  4. Consequences of artificial deepwater ventilation in the Bornholm Basin for oxygen conditions, cod reproduction and benthic biomass - a model study

    NASA Astrophysics Data System (ADS)

    Stigebrandt, A.; Rosenberg, R.; Råman Vinnå, L.; Ödalen, M.

    2015-01-01

    We develop and use a circulation model to estimate hydrographical and ecological changes in the isolated basin water of the Bornholm Basin. By pumping well-oxygenated so-called winter water to the greatest depth, where it is forced to mix with the resident water, the rate of deepwater density reduction increases as well as the frequency of intrusions of new oxygen-rich deepwater. We show that pumping 1000 m3 s-1 should increase the rates of water exchange and oxygen supply by 2.5 and 3 times, respectively. The CRV (cod reproduction volume), the volume of water in the isolated basin meeting the requirements for successful cod reproduction (S > 11, O2 > 2 mL L-1), should every year be greater than 54 km3, which is an immense improvement, since it has been much less in certain years. Anoxic bottoms should no longer occur in the basin, and hypoxic events will become rare. This should permit extensive colonization of fauna on the earlier periodically anoxic bottoms. Increased biomass of benthic fauna should also mean increased food supply to economically valuable demersal fish like cod and flatfish. In addition, re-oxygenation of the sediments should lead to increased phosphorus retention by the sediments.

  5. Modeling and Simulations in Time Domain of a Stimulation Set-up for Cortical Applications

    PubMed Central

    Schweigmann, Michael; Kirchhoff, Frank; Koch, Klaus P.

    2016-01-01

    Electrical stimulation is used for example to treat neuronal disorders and depression with deep brain stimulation or transcranial electrical stimulation. Depending on the application, different electrodes are used and thus different electrical characteristics exist, which have to be handled by the stimulator. Without a measuring device the user would have to rely on the stimulator being able to deliver the needed stimulation signal. Therefore, the objective of this paper is to present a method to increase the level of confidence with characterization and modelling of the electrical behavior by using the example of one channel of our stimulation device for experimental use. In several simulation studies with an electrode model with values in a typical range for cortical applications the influence of the load onto the stimulator and the possibility to pre-estimate measuring signals in complex networks are shown. PMID:27478564

  6. Setting up home-based palliative care in countries with limited resources: a model from Sarawak, Malaysia

    PubMed Central

    Devi, B. C. R.; Corbex, M.

    2008-01-01

    Background: The provision of palliative care (PC) and opioids is difficult to ensure in remote areas in low- and middle-income countries. We describe here the set up of a home-care program in Sarawak (the Malaysian part of the Borneo Island), where half the population lives in villages that are difficult to access. Methods: The establishment of this program, initiated in 1994 by the Department of Radiotherapy of Sarawak General Hospital, consisted of training, empowering nurses, simplifying referral, facilitating access to medication, and increasing awareness among public and health professionals about PC. Results: The program has been sustainable and cost efficient, serving 936 patients in 2006. The total morphine usage in the program increased from <200 g in 1993 to >1400 g in 2006. The results show that pain medication can be provided even in remote areas with effective organization and empowerment of nurses, who were the most important determinants for the set up of this program. Education of family was also a key aspect. Conclusion: The authors believe that the experience gained in Sarawak may help other regions with low or middle resources in the set up of their PC program especially for their remote rural population. PMID:18641007

  7. River Modeling in Large and Ungauged Basins: Experience of Setting up the HEC RAS Model over the Ganges-Brahmaputra-Meghna Basins

    NASA Astrophysics Data System (ADS)

    Hossain, F.; Maswood, M.

    2014-12-01

    River modeling is the processing of setting up a physically-based hydrodynamic model that can simulate the water flow dynamics of a stream network against time varying boundary conditions. Such river models are an important component of any flood forecasting system that forecasts river levels in flood prone regions. However, many large river basins in the developing world such as the Ganges, Brahmaputra, Meghna (GBM), Indus, Irrawaddy, Salween, Mekong and Niger are mostly ungauged. Such large basins lack the necessary in-situ measurements of river bed depth/slope, bathymetry (river cross section), floodplain mapping and boundary condition flows for forcing a river model. For such basins, proxy approaches relying mostly on remote sensing data from space platforms are the only alternative. In this study, we share our experience of setting up the widely-used 1-D river model over the entire GBM basin and its stream network. Good quality in-situ measurements of river hydraulics (cross section, slope, flow) was available only for the downstream and flood prone region of the basin, which comprises only 7% of the basin area. For the remaining 93% of the basin area, we resorted to the use of data from the following satellite sensors to build a workable river model: a) Shuttle Radar Topography Mission (SRTM) for deriving bed slope; b) LANDSAT/MODIS for updating river network and flow direction generated by elevation data; c) radar altimetry data to build depth versus width relationship at river locations; d) satellite precipitation based hydrologic modeling of lateral flows into main stem rivers. In addition, we referred to an extensive body of literature to estimate the prevailing baseline hydraulics of rivers in the ungauged region. We measured success of our approach by systematically testing how well the basin-wide river model could simulate river level dynamics at two measured locations inside Bangladesh. Our experience of river modeling was replete with numerous

  8. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory

    PubMed Central

    Liu, Hongjie; Li, Tianhao; Zhan, Sha; Pan, Meilan; Ma, Zhiguo; Li, Chenghua

    2016-01-01

    Aims. To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs. Methods. The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data. LR prediction model was established and the accuracy of the prediction by this model was evaluated. Results. The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties (p < 0.05), and the coefficient was 0.178 (p < 0.05); also they were related with five flavors (p < 0.05), and the coefficient was 0.145 (p < 0.05); they were not related with channel tropism (p > 0.05). There were totally 12 variables from four properties and five flavors for the LR. Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204. Conclusions. Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity. Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs.

  9. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory

    PubMed Central

    Liu, Hongjie; Li, Tianhao; Zhan, Sha; Pan, Meilan; Ma, Zhiguo; Li, Chenghua

    2016-01-01

    Aims. To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs. Methods. The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data. LR prediction model was established and the accuracy of the prediction by this model was evaluated. Results. The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties (p < 0.05), and the coefficient was 0.178 (p < 0.05); also they were related with five flavors (p < 0.05), and the coefficient was 0.145 (p < 0.05); they were not related with channel tropism (p > 0.05). There were totally 12 variables from four properties and five flavors for the LR. Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204. Conclusions. Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity. Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs. PMID:27656240

  10. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory.

    PubMed

    Liu, Hongjie; Li, Tianhao; Chen, Lingxiu; Zhan, Sha; Pan, Meilan; Ma, Zhiguo; Li, Chenghua; Zhang, Zhe

    2016-01-01

    Aims. To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs. Methods. The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data. LR prediction model was established and the accuracy of the prediction by this model was evaluated. Results. The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties (p < 0.05), and the coefficient was 0.178 (p < 0.05); also they were related with five flavors (p < 0.05), and the coefficient was 0.145 (p < 0.05); they were not related with channel tropism (p > 0.05). There were totally 12 variables from four properties and five flavors for the LR. Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204. Conclusions. Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity. Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs.

  11. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory.

    PubMed

    Liu, Hongjie; Li, Tianhao; Chen, Lingxiu; Zhan, Sha; Pan, Meilan; Ma, Zhiguo; Li, Chenghua; Zhang, Zhe

    2016-01-01

    Aims. To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs. Methods. The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data. LR prediction model was established and the accuracy of the prediction by this model was evaluated. Results. The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties (p < 0.05), and the coefficient was 0.178 (p < 0.05); also they were related with five flavors (p < 0.05), and the coefficient was 0.145 (p < 0.05); they were not related with channel tropism (p > 0.05). There were totally 12 variables from four properties and five flavors for the LR. Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204. Conclusions. Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity. Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs. PMID:27656240

  12. Shear-tensile/implosion source model vs. moment tensor: benefit in single-azimuth monitoring. Cotton Valley set-up.

    NASA Astrophysics Data System (ADS)

    Sileny, J.

    2012-12-01

    Moment tensor (MT) has become a standard for description of seismic sources, both in earthquake seismology and for various types of induced seismicity. It is a general dipole source, but for practice it may be too general, its generality causing troubles during its reconstruction from noisy data in the inverse process, which may be additionally ill-conditioned due to inexact hypocenter location or availability of a rough velocity/attenuation model only. Then, the retrieved source may be biased. It seems reasonable to assume a simpler and intuitivelly more physical source model directly describing the physical phenomena anticipated in the particular focus. A simple combination of a shear slip with tensile crack or 1D implosion (STI) may be a good model both for natural earthquakes and induced events. The model simplification introduced is crucial in cases of depleted sensor configuration when the moment tensor fails, in single-azimuth monitoring in particular. This is just the case of application in oil and gas industry, where the monitoring of seismicity induced by hydrofracturing is typically performed from single monitoring borehole. Then, MT is able to provide constrained solutions only (e.g. deviatoric), but STI detects also non-shear component correctly, providing important information on increase of permeability of the reservoir.

  13. The Objective Borderline Method (OBM): A Probability-Based Model for Setting up an Objective Pass/Fail Cut-Off Score in Medical Programme Assessments

    ERIC Educational Resources Information Center

    Shulruf, Boaz; Turner, Rolf; Poole, Phillippa; Wilkinson, Tim

    2013-01-01

    The decision to pass or fail a medical student is a "high stakes" one. The aim of this study is to introduce and demonstrate the feasibility and practicality of a new objective standard-setting method for determining the pass/fail cut-off score from borderline grades. Three methods for setting up pass/fail cut-off scores were compared: the…

  14. Guide for SDEC Set up

    SciTech Connect

    Bibby, R; Guthrie, E

    2009-01-30

    The instrument has four collection vials that must be filled with ethylene glycol before operation. Each of the four vials should be labeled 1 through 4 and the empty weights recorded. Fill each vial with 80 mL of ethylene glycol and record the weight again. In order for the instrument to operate properly, the collection vials should always have less than 160 mL of total liquid in them. After completing a sample run, remove the collection vials, use a transfer pipette to remove any liquid that might still be on the air paddler, wipe off any condensation from the exterior of the collection vial and record weight. From the instrument, record the ending volume and the time of operation. The solution mixed in the scintillation vial will be 2 ml of a 95% to 50% ethylene glycol to water mixture. To determine the efficiency of counting at all of these concentrations, a series of vials should be set up that consist of 18 ml of Ultima Gold LLT cocktail mixed with standard, regular deionized water and ethylene glycol. The efficiency curve should be counted in the 'Low Level' count mode with the Luminescence Correction ON and the Color Quench Correction ON. Once the tSIE values are determined, chart the cpm against the tSIE numbers and find the best fit for the data. The resulting equation is to be used to converting tSIE values from the collection vials to efficiency. To determine the background cpm value of the ethylene glycol, count a 2 ml sample of ethylene glycol with 18 ml of Ultima Gold for 100 minutes. To determine the total activity of the sample, take two 2 ml aliquots of sample from the first vial and place in separate scintillation vials. Record the weight of each aliquot. Determine the percentage of total sample each aliquot represents by dividing the aliquot weight by the total solution weight from the vial. Also, determine the percentage of ethylene glycol in the sample by dividing the initial solution weight by the final solution weight and multiplying by 100

  15. Setting-up an In Vitro Model of Rat Blood-brain Barrier (BBB): A Focus on BBB Impermeability and Receptor-mediated Transport

    PubMed Central

    Molino, Yves; Jabès, Françoise; Lacassagne, Emmanuelle; Gaudin, Nicolas; Khrestchatisky, Michel

    2014-01-01

    The blood brain barrier (BBB) specifically regulates molecular and cellular flux between the blood and the nervous tissue. Our aim was to develop and characterize a highly reproducible rat syngeneic in vitro model of the BBB using co-cultures of primary rat brain endothelial cells (RBEC) and astrocytes to study receptors involved in transcytosis across the endothelial cell monolayer. Astrocytes were isolated by mechanical dissection following trypsin digestion and were frozen for later co-culture. RBEC were isolated from 5-week-old rat cortices. The brains were cleaned of meninges and white matter, and mechanically dissociated following enzymatic digestion. Thereafter, the tissue homogenate was centrifuged in bovine serum albumin to separate vessel fragments from nervous tissue. The vessel fragments underwent a second enzymatic digestion to free endothelial cells from their extracellular matrix. The remaining contaminating cells such as pericytes were further eliminated by plating the microvessel fragments in puromycin-containing medium. They were then passaged onto filters for co-culture with astrocytes grown on the bottom of the wells. RBEC expressed high levels of tight junction (TJ) proteins such as occludin, claudin-5 and ZO-1 with a typical localization at the cell borders. The transendothelial electrical resistance (TEER) of brain endothelial monolayers, indicating the tightness of TJs reached 300 ohm·cm2 on average. The endothelial permeability coefficients (Pe) for lucifer yellow (LY) was highly reproducible with an average of 0.26 ± 0.11 x 10-3 cm/min. Brain endothelial cells organized in monolayers expressed the efflux transporter P-glycoprotein (P-gp), showed a polarized transport of rhodamine 123, a ligand for P-gp, and showed specific transport of transferrin-Cy3 and DiILDL across the endothelial cell monolayer. In conclusion, we provide a protocol for setting up an in vitro BBB model that is highly reproducible due to the quality assurance methods

  16. Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transport.

    PubMed

    Molino, Yves; Jabès, Françoise; Lacassagne, Emmanuelle; Gaudin, Nicolas; Khrestchatisky, Michel

    2014-01-01

    The blood brain barrier (BBB) specifically regulates molecular and cellular flux between the blood and the nervous tissue. Our aim was to develop and characterize a highly reproducible rat syngeneic in vitro model of the BBB using co-cultures of primary rat brain endothelial cells (RBEC) and astrocytes to study receptors involved in transcytosis across the endothelial cell monolayer. Astrocytes were isolated by mechanical dissection following trypsin digestion and were frozen for later co-culture. RBEC were isolated from 5-week-old rat cortices. The brains were cleaned of meninges and white matter, and mechanically dissociated following enzymatic digestion. Thereafter, the tissue homogenate was centrifuged in bovine serum albumin to separate vessel fragments from nervous tissue. The vessel fragments underwent a second enzymatic digestion to free endothelial cells from their extracellular matrix. The remaining contaminating cells such as pericytes were further eliminated by plating the microvessel fragments in puromycin-containing medium. They were then passaged onto filters for co-culture with astrocytes grown on the bottom of the wells. RBEC expressed high levels of tight junction (TJ) proteins such as occludin, claudin-5 and ZO-1 with a typical localization at the cell borders. The transendothelial electrical resistance (TEER) of brain endothelial monolayers, indicating the tightness of TJs reached 300 ohm x cm(2) on average. The endothelial permeability coefficients (Pe) for lucifer yellow (LY) was highly reproducible with an average of 0.26 ± 0.11 x 10(-3) cm/min. Brain endothelial cells organized in monolayers expressed the efflux transporter P-glycoprotein (P-gp), showed a polarized transport of rhodamine 123, a ligand for P-gp, and showed specific transport of transferrin-Cy3 and DiILDL across the endothelial cell monolayer. In conclusion, we provide a protocol for setting up an in vitro BBB model that is highly reproducible due to the quality assurance

  17. The Objective Borderline method (OBM): a probability-based model for setting up an objective pass/fail cut-off score in medical programme assessments.

    PubMed

    Shulruf, Boaz; Turner, Rolf; Poole, Phillippa; Wilkinson, Tim

    2013-05-01

    The decision to pass or fail a medical student is a 'high stakes' one. The aim of this study is to introduce and demonstrate the feasibility and practicality of a new objective standard-setting method for determining the pass/fail cut-off score from borderline grades. Three methods for setting up pass/fail cut-off scores were compared: the Regression Method, the Borderline Group Method, and the new Objective Borderline Method (OBM). Using Year 5 students' OSCE results from one medical school we established the pass/fail cut-off scores by the abovementioned three methods. The comparison indicated that the pass/fail cut-off scores generated by the OBM were similar to those generated by the more established methods (0.840 ≤ r ≤ 0.998; p < .0001). Based on theoretical and empirical analysis, we suggest that the OBM has advantages over existing methods in that it combines objectivity, realism, robust empirical basis and, no less importantly, is simple to use.

  18. A new test set-up for skull fracture characterisation.

    PubMed

    Verschueren, P; Delye, H; Depreitere, B; Van Lierde, C; Haex, B; Berckmans, D; Verpoest, I; Goffin, J; Vander Sloten, J; Van der Perre, G

    2007-01-01

    Skull fracture is a frequently observed type of severe head injury. Historically, a variety of impact test set-ups and techniques have been used for investigating skull fracture. The most frequently used are the free-fall technique, the guided fall or drop tower set-up and the piston-driven impactor set-up. This document proposes a new type of set-up for cadaver head impact testing which combines the strengths of the most frequently used techniques and devices. The set-up consists of two pendulums, which allow for a 1 degree of freedom rotational motion. The first pendulum is the impactor and is used to strike the blow. The head is attached to the second pendulum using a polyester resin. Local skull deformation and impact force are measured with a sample frequency of 65 kHz. From these data, absorbed energy until skull fracture is calculated. A set-up evaluation consisting of 14 frontal skull and head impact tests shows an accurate measurement of both force and local skull deformation until fracture of the skull. Simplified mechanical models are used to analyse the different impacting techniques from literature as well as the new proposed set-up. It is concluded that the proposed test set-up is able to accurately calculate the energy absorbed by the skull until fracture with an uncertainty interval of 10%. Second, it is concluded that skull fracture caused by blunt impact occurs before any significant motion of the head. The two-pendulum set-up is the first head impact device to allow a well-controlled measurement environment without altering the skull stress distribution.

  19. Setting-Up, Calibrating and Validating Hydrodynamic Models on the Basis of Remotely-Sensed Data Only: Are We There Yet?

    NASA Astrophysics Data System (ADS)

    Domeneghetti, A.

    2015-12-01

    The greater availability of remote sensing data stimulates the scientific community to resort to these new data sources in order to pursue a greater spatial coverage of hydraulic models, even in remote and data-sparse areas. However, the accuracy of hydrological and hydraulic models performed in absence of measured topography data suffers from the lack of knowledge of the river bathymetry, which cannot be directly inferred from satellite instruments. This work, adopting the SRTM (Shuttle Radar Topography Mission) for representing the riverbed and floodplain morphology, tests two different procedures for inferring the river bathymetry under the water surface level, thus enhancing the accuracy of space-borne digital elevation model and its suitability for hydraulic applications. Referring to a river stretch of about 140 km of the Po river, the study investigates the suitability of 1) altimetry data (i.e., ERS-2 and ENVISAT) and 2) SRTM-based river cross-sections modified according to two approaches (Channel Bankfull depth (CB) and Slope-Break (SB) approach), for the implementation and calibration of 1D numerical models. Simulation results are compared with those obtained by means of a quasi-2D model implemented with detailed topographical data (i.e. airborne LiDAR), and show that both SRTM-based models based on CB and SB approaches appear accurate enough to reproduce the hydrometric regime of the river stretch. In particular, despite the SB approach does not require any field data, it provides efficiency values (NSs) and errors of the same order of LiDAR-based model. Even though the accuracy of SRTM-based models is still not adequate for detailed analysis (i.e., local flood-risk estimate), the study further emphasizes the suitability of space-borne topography data (e.g. SRTM), combined with remotely sensed altimetry data (i.e., ERS-2 and ENVISAT), for the implementation of large-scale analysis (i.e., global flood risk analysis), even in absence of field measurements.

  20. Automatic set up of SHETRAN for catchments in Great Britain

    NASA Astrophysics Data System (ADS)

    Lewis, Elizabeth; Kilsby, Chris; Fowler, Hayley

    2014-05-01

    Physically-based spatially-distributed (PBSD) models may provide a robust framework for simulating catchment processes in ungauged catchments and under climatic variability. However, they are often overlooked in catchment studies in favour of their conceptual or lumped counterparts. This is because conceptual models are easy and rapid to set up, and can be finely tuned using historic data to give excellent simulation results. On the other hand PBSD models, such as SHETRAN developed at Newcastle University, require much more input data and take weeks or months to set up. To overcome these problems and to promote the use of SHETRAN, this project has set up an easy-to-use, accessible system of hydrological models across Great Britain to be used for both catchment scale studies and countrywide analysis of river flows under present and future conditions. An interface for this system has been developed to make the usually long and tedious setup of PBSD models quick and easy. A non-expert user can now set up a robust and reliable model for a catchment within Great Britain within 10 seconds, a process which would usually take weeks. The user can select a catchment from one of the 1457 boundaries identified in the National River Flow Archive, or they can upload their own catchment boundary as a shapefile. The system therefore has great flexibility for use in setting up models of gauged and ungauged catchments. PBSD models require a lot of data (DEM, geology, soil, land cover), often available in only an inappropriate format. The data behind this system is freely accessible under an academic licence and downloadable from various publicly funded bodies. These data layers have been converted into the correct format for use with SHETRAN, which is also freely available and is provided with every model set up.

  1. Adaptation of the pseudo-metal-oxide-semiconductor field effect transistor technique to ultrathin silicon-on-insulator wafers characterization: Improved set-up, measurement procedure, parameter extraction, and modeling

    NASA Astrophysics Data System (ADS)

    Van Den Daele, W.; Malaquin, C.; Baumel, N.; Kononchuk, O.; Cristoloveanu, S.

    2013-10-01

    This paper revisits and adapts of the pseudo-MOSFET (Ψ-MOSFET) characterization technique for advanced fully depleted silicon on insulator (FDSOI) wafers. We review the current challenges for standard Ψ-MOSFET set-up on ultra-thin body (12 nm) over ultra-thin buried oxide (25 nm BOX) and propose a novel set-up enabling the technique on FDSOI structures. This novel configuration embeds 4 probes with large tip radius (100-200 μm) and low pressure to avoid oxide damage. Compared with previous 4-point probe measurements, we introduce a simplified and faster methodology together with an adapted Y-function. The models for parameters extraction are revisited and calibrated through systematic measurements of SOI wafers with variable film thickness. We propose an in-depth analysis of the FDSOI structure through comparison of experimental data, TCAD (Technology Computed Aided Design) simulations, and analytical modeling. TCAD simulations are used to unify previously reported thickness-dependent analytical models by analyzing the BOX/substrate potential and the electrical field in ultrathin films. Our updated analytical models are used to explain the results and to extract correct electrical parameters such as low-field electron and hole mobility, subthreshold slope, and film/BOX interface traps density.

  2. Setting Up Private Practice in Psychiatry*

    PubMed Central

    De Sousa, Alan; De Sousa, Avinash

    2015-01-01

    Setting up a private practice in Mumbai is an onerous task. The present paper looks at the difficulties face by young psychiatrists when starting a private practice in psychiatry. It suggests certain guidelines to be followed to ensure the development of a successful practice. It also suggests methods to gain popularity among patients and society along with the ethics to be followed, knowledge base to be garnered, and the role of using multiple therapies and versatility in private practice. PMID:25838718

  3. Setting up the Pediatric Endoscopy Unit.

    PubMed

    Lerner, Diana G; Pall, Harpreet

    2016-01-01

    As pediatric gastrointestinal endoscopy continues to develop and evolve, pediatric gastroenterologists are more frequently called on to develop and direct a pediatric endoscopy unit. Lack of published literature and focused training in fellowship can render decision making about design, capacity, operation, equipment purchasing, and staffing challenging. To help guide management decisions, we distributed a short survey to 18 pediatric gastroenterology centers throughout the United States and Canada. This article provides practical guidance by summarizing available expert opinions on the topic of setting up a pediatric endoscopy unit. PMID:26616893

  4. Trappers set up trap for lizard

    NASA Technical Reports Server (NTRS)

    2000-01-01

    In hope of catching a large monitor lizard seen in the area, state-licensed animal trappers Dewey Kessler and James Dean (at left), with Gary Povitch (kneeling) of the U.S. Wildlife and Dan Turner (standing) set up a trap on KSC. The lizard has been spotted recently near S.R. 3, a route into the Center, by several area residents. Turner is a monitor expert. The lizard is not a native of the area, and possibly a released pet. Dean is working with the cooperation of KSC and the Merritt Island National Wildlife Refuge.

  5. Petroleum geology and play assessment, Bornholm Area, Denmark

    SciTech Connect

    Joergensen, N.B.

    1988-01-01

    The Bornholm area is in the easternmost part of the Danish license area of northwest Europe, where it is part of the mobile border zone between the stable Fennoscandian shield and the subsiding Danish-Polish trough. The Bornholm area is dominated by a complicated pattern of grabens and uplift horst blocks, of which the island of Bornholm is one. The horst blocks are parallel with the general northwest-southeast trend of the border zone, but major grabens are perpendicular to this trend. The most prominent one is the Ronne graben, in which up to 2 km of Paleozoic and Mesozoic sediment are present. Cambrian-Silurian rocks are present over most of the Bornholm area, whereas substantial thicknesses of Mesozoic sediments are more or less restricted to the southwestern part. Devonian-Early Triassic rocks are not seen in outcrop but may be present in the deeper grabens. During the Late Cretaceous-early Tertiary Laramide orogeny, part of the area was uplifted as much as 1-2 km. Source rocks are probably lower Paleozoic, high-TOC, shelf mudstones, and possibly Upper Carboniferous coal measures, and Jurassic coal measures. Due to its proximity to the Fennoscandian shield, clastic sediment has been supplied to the Bornholm area throughout geologic history. A wide range of structural traps resulted from normal extension, strike-slip faulting, and inversion. Although the Bornholm area is virtually unexplored for hydrocarbons, the presence of surrounding, structurally related oil and gas provinces makes the area a logical target for exploration today.

  6. Platform for setting up interactive virtual environments

    NASA Astrophysics Data System (ADS)

    Souza, Danilo; Dias, Paulo; Santos, Daniel; Sousa Santos, Beatriz

    2014-02-01

    This paper introduces pSIVE, a platform that allows the easy setting up of Virtual Environments, with interactive information (for instance, a video or a document about a machine that is present in the virtual world) to be accessed for different 3D elements. The main goal is to create for evaluation and training on a virtual factory - but generic enough to be applied in different contexts by non-expert users (academic and touristic for instance). We show some preliminary results obtained from two different scenarios: first a production line of a factory with contextualized information associated to different elements which aimed the training of employees. Second a testing environment, to compare and assess two different selection styles that were integrated in pSIVE and to allow different users to interact with an environment created with pSIVE to collect opinions about the system. The conclusions show that the overall satisfaction was high and the comments will be considered in further platform development.

  7. Petroleum geology and play assessment, Bornholm area, Denmark

    SciTech Connect

    Joergensen, N.B.

    1988-02-01

    The Bornholm area is dominated by a complicated pattern of grabens and uplift horst blocks, of which the island of Borhnolm is one. The horst blocks are parallel with the general northwest-southeast trend of the border zone, but major grabens arc perpendicular to this trend. The most prominent one is the Ronne graben, in which up to 2 km of Paleozoic and Mesozoic sediment are present. Cambrian-Silurian rocks are present over most of the Bornholm area, whereas substantial thicknesses of mesozoic sediments are more or less restricted to the southwestern part. Devonian-Early Triassic rocks are not seen in outcrop but may be present in the deeper grabens. During the Late Cretaceous-early Tertiary Laramide orogeny, part of the area was uplifted as much as 1-2 km. Source rocks are probably lower Paleozoic, high-TOC, shelf mudstones, and possibly Upper Carboniferous coal measures, and Jurassic coal measures. Due to its proximity to the Fennoscandian shield, clastic sediment has been supplied to the Bornholm area throughout geologic history. A wide range of structural traps resulted from normal extension, strike-slip faulting, and inversion. Although the Bornholm area is virtually unexplored for hydrocarbons, the presence of surrounding, structurally related oil and gas provinces makes the area a logical target for exploration today.

  8. Technician Setting up RCA Television Camera

    NASA Technical Reports Server (NTRS)

    1957-01-01

    A television camera is focused by NACA technician on a ramjet engine model through the schlieren optical windows of the 10 x 10 Foot Supersonic Wind Tunnel's test section. Closed-circuit television enables aeronautical research scientists to view the ramjet, used for propelling missiles, while the wind tunnel is operating at speeds from 1500 to 2500 mph. (8.570) The tests were performed at the Lewis Flight Propulsion Laboratory, now John H. Glenn Research Center.

  9. INTERIOR PERSPECTIVE, LOOKING SOUTH SOUTHWEST WITH FIELD SET UP IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR PERSPECTIVE, LOOKING SOUTH SOUTHWEST WITH FIELD SET UP IN FOOTBALL CONFIGURATION. FIELD SEATING ROTATES TO ACCOMMODATE BASEBALL GAMES. - Houston Astrodome, 8400 Kirby Drive, Houston, Harris County, TX

  10. Computer Center: Setting Up a Microcomputer Center--1 Person's Perspective.

    ERIC Educational Resources Information Center

    Duhrkopf, Richard, Ed.; Collins, Michael, A. J., Ed.

    1988-01-01

    Considers eight components to be considered in setting up a microcomputer center for use with college classes. Discussions include hardware, software, physical facility, furniture, technical support, personnel, continuing financial expenditures, and security. (CW)

  11. 9. VIEW SOUTHSOUTHEAST STERN OF JFK, SCAFFOLDING SET UP FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. VIEW SOUTH-SOUTHEAST STERN OF JFK, SCAFFOLDING SET UP FOR REMOUNTING OF PROPELLERS. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Dry Dock No. 5, League Island, Philadelphia, Philadelphia County, PA

  12. A Magnetic Set-Up to Help Teach Newton's Laws

    ERIC Educational Resources Information Center

    Panijpan, Bhinyo; Sujarittham, Thanida; Arayathanitkul, Kwan; Tanamatayarat, Jintawat; Nopparatjamjomras, Suchai

    2009-01-01

    A set-up comprising a magnetic disc, a solenoid and a mechanical balance was used to teach first-year physics students Newton's third law with the help of a free body diagram. The image of a floating magnet immobilized by the solenoid's repulsive force should help dispel a common misconception of students as regards the first law: that stationary…

  13. Guidelines for Setting Up Support Groups in the Schools.

    ERIC Educational Resources Information Center

    Spang, Bruce P.; Redding, Judith M.

    This document provides guidelines for setting up support groups in the schools designed to manage the problems associated with chemical use and abuse. Sections on group membership, the support group as a learner-centered educational experience, and purposes of the support group are presented. Sources of student referrals from the school, family,…

  14. Hands-on Science. Getting Set Up for Science.

    ERIC Educational Resources Information Center

    Kepler, Lynne

    1998-01-01

    Presents strategies for getting organized and creating a classroom environment that promotes science learning for primary students. Teachers must first decide what topics they are going to cover and what materials they need. Next, they should determine how to organize the materials. Finally, they should identify and set up areas in the classroom…

  15. Setting Up a Customer Network to Review Documentation.

    ERIC Educational Resources Information Center

    Bist, Gary; And Others

    1993-01-01

    Describes setting up a customer review network, using computer networks and fax machines, to collect customer feedback on documentation during the stages of designing and writing the information. Describes the electronic feedback from one customer in particular and how it was analyzed and used to modify the information before releasing it. (SR)

  16. Estimating the spatial distribution of evapotranspiration using the water balance model WAVE and fine spatial resolution airborne remote sensing images from the DAIS-sensor: Experimental set-up

    NASA Astrophysics Data System (ADS)

    Verstraeten, W. W.; Veroustraete, F.; Feyen, J.

    2003-04-01

    Actual evapotranspiration (ET) of agricultural land and forestland surfaces play an important role in the redistribution of water on the Earth's surface. Any change in evapotranspiration, either through change in vegetation or climate change, directly effects the available water resources. For quantifying these effects physical models need to be constructed. Most hydrological models have to deal with a lack of good spatial resolution, despite their good temporal information. Remote sensing techniques on the contrary determine the spatial pattern of landscape features and hence are very useful on large scales. The main objective of this research is the combination of the spatial pattern of remote sensing (using visible and thermal infrared spectrum) with the temporal pattern of the water balance model WAVE (Vanclooster et al., 1994 and 1996). To realise this, the following objectives are formulated: (i) relate soil and vegetation surface temperatures to actual evapotranspiration of forest and crops simulated with the water balance model WAVE using remote sensing derived parameters. Three methods will be used and mutually compared. Both airborne and satellite imagery will be implemented; (1) compare the spatial pattern of evapotranspiration, as a result of the three methods, with the energy balance model SEBAL (Bastiaanssen et al., 1998) and finally; (2) subject the up-scaled WAVE and SEBAL models to an uncertainty analysis using the GLUE-approach (Generalised Likelihood Uncertainty Estimate) (Beven en Binley, 1992). To study the behaviour of the model beyond the field-scale (micro-scale), a meso-scale study was conducted at the test-site of DURAS (50°50'38"N, 5°08'50"W, Sint-Truiden). Airborne imagery from the DAIS/ROSIS sensor are available. For the determination of the spatial pattern of actual evapotranspiration the next two methods are considered: (1) relations between surface temperature, surface albedo and vegetation indices are linked with field

  17. Essential Requirements to Setting up an Aesthetic Practice

    PubMed Central

    Sachdev, Mukta; Britto, Gillian R

    2014-01-01

    Aesthetic dermatology is becoming a vital and popular branch of medicine. This article aims to guide dermatologists to set up a professional and ethical aesthetic practice. Dermatologists should have an integrated practice of clinical dermatology, dermatosurgery and cosmetic dermatology. Ethical practice is the gold standard for any medical field, especially with dermatologists, who should avoid doing unnecessary procedures. Proper patient counselling and addressing the patients’ concerns is imperative. PMID:25538440

  18. Setting Up a Necessary Guidance Model for the Educational System

    ERIC Educational Resources Information Center

    Fang, Cai

    2005-01-01

    There are three pressures facing China's employment problems: (1) The re-employment of laid-off workers; (2) The employment of rural workers who have come to the cities from the countryside seeking work; and (3) The university students who are entering the workforce for the first time. These three pressures on the labor market have different…

  19. A dynamometer set up for simulation of a wave energy operated Wells turbine

    SciTech Connect

    Narayanan, S.S.Y.; Bose, S.

    1995-12-31

    The present trend in the world is to go for ecologically friendly methods of power generation. In this paper a dynamometer set up simulating a wave energy driven Wells turbine with proper scaling is proposed. This is a new dynamic drive test set up for evaluation of alternative generator configurations. Open loop and closed loop (P, PI and PLL controllers with speed and current feedbacks) studies are carried out on the set up. The references used as input in the closed loop simulations, vary dynamically as the data recorded at the site. The behavior of a typical wave energy operated Wells turbine is studied and simulations are also carried out with axial velocity given as input. Both steady state and d-q theory approaches are used for the modeling of the load induction generator feeding power to the grid.

  20. A magnetic set-up to help teach Newton's laws

    NASA Astrophysics Data System (ADS)

    Panijpan, Bhinyo; Sujarittham, Thanida; Arayathanitkul, Kwan; Tanamatayarat, Jintawat; Nopparatjamjomras, Suchai

    2009-11-01

    A set-up comprising a magnetic disc, a solenoid and a mechanical balance was used to teach first-year physics students Newton's third law with the help of a free body diagram. The image of a floating magnet immobilized by the solenoid's repulsive force should help dispel a common misconception of students as regards the first law: that stationary objects are not being acted on by any force at all. Dropping the magnet onto the electrified solenoid, which can change polarity, can lead to more sophisticated elaboration of the second law.

  1. Quantifying the accuracy of laboratory SIP experimental set ups

    NASA Astrophysics Data System (ADS)

    Ntarlagiannis, D.; Slater, L. D.

    2014-12-01

    Over the last decade the spectral induced polarization (SIP) method has reemerged as a promising method for subsurface investigations. The sensitivity of SIP to bulk and interfacial physicochemical properties permits a wider range of hydrogeophysical and environmental applications, including monitoring of subsurface biogeochemical transformations. Improvements in instrumentation and experimental designs, along with faster acquisition capabilities and easy access to processing routines are encouraging novel applications of the method, and support quantitative interpretation of the data acquired. Motivated by recent research that focus on small scale changes, over large frequency ranges, we performed a series of experiments to identify the accuracy of common laboratory SIP experimental set ups. We performed measurements on resistor - capacitor (RC) networks, to identify the instrumentation accuracy, and also on standard laboratory columns filled with materials of known SIP response, primarily on well characterized fluids of different conductivity. Early results show small errors in the low frequency range, attributed to electrode polarization; in higher frequencies, typically above 1000 Hz, the errors may become significant limiting the meaningful interpretation of small phase angles at these frequencies. The data will be compared with published data using comparable experimental set ups, and could be used to set realistic expectations on future SIP experiments and applications. With this work we aim at developing a best practices document that can aid the SIP user in collecting meaningful and repeatable results.

  2. Calibration of a Background Oriented Schlieren (BOS) Set-up

    NASA Astrophysics Data System (ADS)

    Porta, David; Echeverría, Carlos; Cardoso, Hiroki; Aguayo, Alejandro; Stern, Catalina

    2014-11-01

    We use two materials with different known indexes of refraction to calibrate a Background Oriented Schlieren (BOS) experimental set-up, and to validate the Lorenz-Lorentz equation. BOS is used in our experiments to determine local changes of density in the shock pattern of an axisymmetric supersonic air jet. It is important to validate, in particular, the Gladstone Dale approximation (index of refraction close to one) in our experimental conditions and determine the uncertainty of our density measurements. In some cases, the index of refraction of the material is well known, but in others the density is measured and related to the displacement field. We acknowledge support from UNAM through DGAPA PAPIIT IN117712 and the Graduate Program in Mechanical Engineering.

  3. Totally endoscopic set-up for mitral valve repair.

    PubMed

    Walcot, Nicholas; Hohenberger, Wolfgang; Lakew, Fitsum; Batz, Gerhard; Diegeler, Anno; Perier, Patrick

    2015-01-01

    Minimally invasive mitral surgery is increasingly recognized as routine. We describe here the financially economical set-up for totally endoscopic surgery, which also represents currently the smallest surgical access, limited only by prosthesis and retractor size. This allows the full range of repairs to be performed. Cannulation for cardiopulmonary bypass is performed via the groin. A cosmetic, periareolar (in males) or inframammary fold (in females) incision is made and the chest entered on bypass. An aortic cross-clamp and crystalloid cardioplegia are used via the aortic root prior to atriotomy and surgical repair. This method gives the highest level of cosmesis available and minimal discomfort, without compromising on the extremely good published results.

  4. Geochemistry and petrogenesis of Mesoproterozoic A-type granitoids from the Danish island of Bornholm, southern Fennoscandia

    NASA Astrophysics Data System (ADS)

    Johansson, Åke; Waight, Tod; Andersen, Tom; Simonsen, Siri L.

    2016-02-01

    continental shear zone as a tentative model for the Mesoproterozoic magmatism on Bornholm. However, a close relationship to the nearby Hallandian tectono-magmatic activity in southern Sweden, attributed to continental margin orogenic processes, is also evident. Intermediate magmas presumably formed by ponding of enriched mantle-derived basic magma at the crust-mantle boundary or within the lower crust, causing extensive partial melting and assimilation of mafic to intermediate crustal rocks related to the Transcandinavian Igneous Belt. The magmas then evolved to granitic compositions by removal of an assemblage similar to that seen petrographically, i.e. plagioclase, amphibole, magnetite, titanite, and late-stage K-feldspar.

  5. Traveltime tomography as part of an integrated geophysical investigation of black shales on Bornholm, Denmark

    NASA Astrophysics Data System (ADS)

    Baumann-Wilke, M.; Bauer, K.; Stiller, M.

    2011-12-01

    In October 2010 measurements using different geophysical methods were carried out on the Danish island Bornholm. They are part of a mainly seismic investigation and characterization of black shales. Black shales are sedimentary rocks with a high content of organic carbon, which leads to a dark grayish to black color. Because of their potential to contain oil or gas, black shales are of great interest for the support of the worldwide energy supply. Our general objective is to determine basic seismic properties (P-wave velocity, P/S-wave velocity ratio, attenuation) in an exposed quasi in-situ situation and to relate the results to core and downhole logging data describing reservoir properties. The results will later be used to study the relationship between reservoir properties and seismic reflection attributes. The experiments were carried out at two locations around new drill sites. Three different methods were used: geoelectrical measurements, ambient noise recordings and seismic measurements. In this context we will only concentrate on the presentation of the latter one for one location. At this location, two about 700 m long seismic profiles were measured. It is known from a drilling campaign that the top of the black shale is in about 8 m depth. First, a 1D P-wave velocity model was determined by ray tracing. This model was used as an input for a tomographic inversion to obtain a 2D velocity model. We will show first results of the traveltime tomography for both profiles. A vertical velocity profile through the final model is compared to borehole information.

  6. Numerical dosimetry for cells under millimetre-wave irradiation using Petri dish exposure set-ups.

    PubMed

    Zhao, J X

    2005-07-21

    We carried out a numerical dosimetry study for in vitro experiments on millimetre-wave (MMW) biological effects on cells. The cell layers are cultured in 35 mm Petri dishes placed in the far-field region of a rectangular horn irradiator generating a 50.0 GHz continuous sinusoidal MMW. The finite-difference time-domain (FDTD) method and the second-order approximation of the absorbing boundary conditions (ABCs) are applied in calculating the specific absorption rate (SAR) in the cells. The 0.125 mm and 0.25 mm voxel models of the Petri dish are used. The permittivity and the conductivity of the cells and those of the culture medium are obtained with Debye's dispersion equation. We measured the power pattern of the irradiator using the plane wave expansion (PWE) method, and developed a program module to calculate the FDTD-compatible incident field from the irradiator, whose position and orientation are adjustable. The MMW multiple reflection between the Petri dish and the irradiator is evaluated before being neglected. For the single-dish, double-dish and quadruple-dish exposure set-ups, the SAR intensity and the SAR uniformity are analysed and compared. The meniscus effect on the SAR distribution over the cell layer is evaluated for the single-dish set-up. The influence of the Petri dish interaction on the SAR distribution is examined for the double-dish and quadruple-dish set-ups.

  7. Early Cambrian wave-formed shoreline deposits: the Hardeberga Formation, Bornholm, Denmark

    NASA Astrophysics Data System (ADS)

    Clemmensen, Lars B.; Glad, Aslaug C.; Pedersen, Gunver K.

    2016-09-01

    During the early Cambrian, the Danish island Bornholm was situated on the northern edge of the continent Baltica with palaeolatitudes of about 35°S. An early Cambrian (Terreneuvian) transgression inundated large areas of Baltica including Bornholm creating shallow marine and coastline environments. During this period, wave-formed shoreline sediments (the Vik Member, Hardeberga Formation) were deposited on Bornholm and are presently exposed at Strøby quarry. The sediments consist of fine- and medium-grained quartz-cemented arenites in association with a few silt-rich mudstones. The presence of well-preserved subaqueous dunes and wave ripples indicates deposition in a wave-dominated upper shoreface (littoral zone) environment, and the presence of interference ripples indicates that the littoral zone environment experienced water level fluctuations due to tides and/or changing meteorological conditions. Discoidal structures (medusoids) are present in the quarry, but due to the relative poor preservation of their fine-scale structures it is difficult to determine if the discoids represent true medusae imprints or inorganic structures. The preservation of the shallow-water bedforms as well as the possible medusae imprints is related to either the formation of thin mud layers, formed during a period of calm water when winds blew offshore for a longer period, or to the growth of bacterial mats. The orientation of the wave-formed bedforms indicates a local palaeoshoreline trending NE-SW and facing a large ocean to the north.

  8. How to set up a Joint Information Center

    SciTech Connect

    Miller, M.

    1996-08-01

    Who`s in charge of communicating with the press and public during an oil spill or other emergency response incidents, and how should those communications be coordinated among all the local, state, and federal agencies and the responsible party? This paper explains how agencies and the responsible party are expected to establish a Joint Information Center (JIC) under PREP Guidelines and most Area Contingency Plans for oil spills. Unfortunately, PREP guidelines do not define the JIC`s organizational structure or standard operating procedures, nor do most area contingency plans or the responsible party`s facility or vessel response plans. This paper includes an overview of three different JIC models from the Pacific Northwest Oil Spill Public Affairs Group, Oak Ridge Institute for Science and Education, and the Federal Emergency Management Agency. The authors recommend that a multi-agency task force be created to develop a multi-hazard JIC model that can be adopted as a national standard under NlIMS and PREP guidelines.

  9. Improving oxygen conditions in the deeper parts of bornholm sea by pumped injection of winter water.

    PubMed

    Stigebrandt, Anders; Kalén, Ola

    2013-09-01

    Vertical diffusivity and oxygen consumption in the basin water, the water below the sill level at about 59 m depth, have been estimated by applying budget methods to monitoring data from hydrographical stations BY4 and BY5 for periods without water renewal. From the vertical diffusivity, the mean rate of work against the buoyancy forces below 65 m depth is estimated to about 0.10 mW m(-2). This is slightly higher than published values for East Gotland Sea. The horizontally averaged vertical diffusivity κ can be approximated by the expression κ = a 0 N (-1) where N is the buoyancy frequency and a 0 ≈ 1.25 × 10(-7) m(2) s(-2), which is similar to values for a 0 used for depths below the halocline in Baltic proper circulation models for long-term simulations. The contemporary mean rate of oxygen consumption in the basin water is about 75 g O2 m(-2) year(-1), which corresponds to an oxidation of 28 g C m(-2) year(-1). The oxygen consumption in the Bornholm Basin doubled from the 1970s to the 2000s, which qualitatively explains the observed increasing frequency and vertical extent of anoxia and hypoxia in the basin water in records from the end of the 1950s to present time. A horizontally averaged vertical advection-diffusion model of the basin water is used to calculate the effects on stratification and oxygen concentration by a forced pump-driven vertical convection. It is shown that the residence time of the basin water may be reduced by pumping down and mixing the so-called winter water into the deepwater. With the present rate of oxygen consumption, a pumped flux of about 25 km(3) year(-1) would be sufficient to keep the oxygen concentration in the deepwater above 2 mL O2 L(-1). PMID:23161366

  10. Uncertainty in patient set-up margin analysis in radiation therapy.

    PubMed

    Suzuki, Junji; Tateoka, Kunihiko; Shima, Katsumi; Yaegashi, Yuji; Fujimoto, Kazunori; Saitoh, Yuichi; Nakata, Akihiro; Abe, Tadanori; Nakazawa, Takuya; Sakata, Kouichi; Hareyama, Masato

    2012-07-01

    We investigated the uncertainty in patient set-up margin analysis with a small dataset consisting of a limited number of clinical cases over a short time period, and propose a method for determining the optimum set-up margin. Patient set-up errors from 555 registration images of 15 patients with prostate cancer were tested for normality using a quantile-quantile (Q-Q) plot and a Kolmogorov-Smirnov test with the hypothesis that the data were not normally distributed. The ranges of set-up errors include the set-up errors within the 95% interval of the entire patient data histogram, and their equivalent normal distributions were compared. The patient set-up error was not normally distributed. When the patient set-up error distribution was assumed to have a normal distribution, an underestimate of the actual set-up error occurred in some patients but an overestimate occurred in others. When using a limited dataset for patient set-up errors, which consists of only a small number of the cases over a short period of time in a clinical practice, the 2.5% and 97.5% intervals of the actual patient data histogram from the percentile method should be used for estimating the set-up margin. Since set-up error data is usually not normally distributed, these intervals should provide a more accurate estimate of set-up margin. In this way, the uncertainty in patient set-up margin analysis in radiation therapy can be reduced.

  11. Best practices sharing: Setting up a professional clinical research unit in India

    PubMed Central

    Divate, Uma; Das, Soma; Bhosale, Neelambari; Divate, Pathik

    2014-01-01

    The Drug Controller General of India has recently come up with very stringent laws to tighten the regulatory framework around clinical trials. One-way of improving the credibility of India and its researchers in the eyes of the regulators, sponsors and the general public is through professional site management team or setting up clinical research unit (CRU). The CRU acts as a bridge between the sponsor and the investigator. The CRU model has been better explained with the help of a good example of a clinical research institute. Since, a successful clinical trial needs high quality data, timeliness and clear communication between all parties, a professional CRU with a team of dedicated and trained professionals and infrastructure with written procedures and policies may be a solution to the pain and agony of poor site performance and investigator insufficiency and pressure. PMID:24551586

  12. FTIR free-jet set-up for the high resolution spectroscopic investigation of condensable species

    NASA Astrophysics Data System (ADS)

    Georges, R.; Bonnamy, A.; Benidar, A.; Decroi, M.; Boissoles, J.

    2002-05-01

    An existing experimental set-up combining Fourier transform infrared (FTIR) spectroscopy and free-jet cooling has been modified significantly to allow high resolution studies of the spectrum of monomer species which are liquid under standard conditions. Evaporation of the liquid samples is controlled by a condenser apparatus which is described. A supersonic planar expansion issuing from a narrow aperture is preferred for its very high cooling rate. Such an expansion, probed with a pitot tube, has a zone of limited temperature gradient close to the nozzle exit. The continuum isentropic model appears well suited to describing the thermodynamic properties of the flow up to a high number of nozzle diameters downstream. High resolution spectra of benzene and methanol have been recorded in the 3 µm wavelength range, and their analysis demonstrates a well defined rotational temperature in the 20-25 K range.

  13. Setting up and functioning of an Emergency Medicine Department: Lessons learned from a preliminary study

    PubMed Central

    Asish, K; Suresh, Varun

    2016-01-01

    Background and Aims: Tertiary care teaching hospitals remain referral centres for victims of trauma and mass casualty. Often specialists from various disciplines manage these crowded casualty areas. These age old casualty areas are being replaced, throughout the country by Emergency Medicine Departments (EMDs), presumed to be better planned to confront a crisis. We aimed to gather basic data contributive in setting up of an EMD at a tertiary care teaching hospital from the lessons learned from functioning existent systems. Methods: This is primarily a questionnaire-based descriptive study at tertiary care referral centres across the country, which was purposively selected. The study models included one from a hospital without designated EMD and the other four from hospitals with established EMDs. Direct observation and focus group meetings with experienced informants at these hospitals contributed to the data. In the absence of a validated hospital preparedness assessment scale, comparison was done with regard to quantitative, qualitative and corroborative parameters using descriptive analysis. Results: The EMDs at best practice models were headed by specialist in Emergency Medicine assisted by organised staff, had protocols for managing mass casualty incident (MCI), separate trauma teams, ergonomic use of infrastructure and public education programmes. In this regard, these hospitals seemed well organised to manage MCIs and disasters. Conclusion: The observation may provide a preliminary data useful in setting up an EMD. In the absence of published Indian literature, this may facilitate further research in this direction. Anaesthesiologists, presently an approved Faculty in Emergency Medicine training can provide creative input with regard to its initial organisation and functioning, thus widening our horizons in a country where there is a severe dearth of trained emergency physicians. PMID:27013749

  14. Overhauling and Regulating Schools Set Up by Migrants: The Reason for Overhaul

    ERIC Educational Resources Information Center

    Jianzhong, Ding

    2004-01-01

    The article presents information on overhauling and regulating schools set up by migrants in the Pudong New District of China. As the number of migrants has risen sharply in the Pudong New District in recent years, so has the number of migrant children. An overall investigation of the fifty-nine schools set up by migrants was conducted and the…

  15. Setting up and Running a School Library. Information Collection and Exchange Publication No. ED204

    ERIC Educational Resources Information Center

    Baird, Nicola

    2012-01-01

    This book explains how teachers can set up and run a successful school library. In it you will find advice and information on how to: (1) set up a small library and build bookshelves; (2) select books for your library; (3) make a written record of your school's books, pamphlets and other library stock such as newspapers, magazines, audio tapes and…

  16. Steps To Help Your School Set Up an AIDS Education Program. Revised.

    ERIC Educational Resources Information Center

    National Coalition of Advocates for Students, Boston, MA.

    This guide for setting up an educational program on Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) is divided into four sections: (1) "A School's Role"; (2) "How To Help Your School Set Up a Good HIV and AIDS Education Program"; (3) "A Checklist for Picking a Good HIV Curriculum"; and (4) "Resources." The first…

  17. Simulating the X-Ray Image Contrast to Set-Up Techniques with Desired Flaw Detectability

    NASA Technical Reports Server (NTRS)

    Koshti, Ajay M.

    2015-01-01

    The paper provides simulation data of previous work by the author in developing a model for estimating detectability of crack-like flaws in radiography. The methodology is being developed to help in implementation of NASA Special x-ray radiography qualification, but is generically applicable to radiography. The paper describes a method for characterizing X-ray detector resolution for crack detection. Applicability of ASTM E 2737 resolution requirements to the model are also discussed. The paper describes a model for simulating the detector resolution. A computer calculator application, discussed here, also performs predicted contrast and signal-to-noise ratio calculations. Results of various simulation runs in calculating x-ray flaw size parameter and image contrast for varying input parameters such as crack depth, crack width, part thickness, x-ray angle, part-to-detector distance, part-to-source distance, source sizes, and detector sensitivity and resolution are given as 3D surfaces. These results demonstrate effect of the input parameters on the flaw size parameter and the simulated image contrast of the crack. These simulations demonstrate utility of the flaw size parameter model in setting up x-ray techniques that provide desired flaw detectability in radiography. The method is applicable to film radiography, computed radiography, and digital radiography.

  18. Prototype electron lens set-up for the Tevatron beam-beam compensation

    SciTech Connect

    Crawford, C.; Saewert, G.; Santucci, J.; Sery, A.; Shemyakin, A.; Shiltsev, V.; Wildman, D.; Aleksandrov, A.; Arapov, L.; Kuznetsov, G.; Logachov, P.; Sharapa, A.; Skarbo, B.; Sukhina, B.

    1999-05-17

    A prototype "electron lens" for the Tevatron beam-beam compensation project is commissioned at Fermilab. We de-scribe the set-up, report results of the first tests of the elec-tron beam, and discuss future plans.

  19. Performance tolerance and boat set-up in elite sprint kayaking.

    PubMed

    Ong, Kuan; Elliott, Bruce; Ackland, Tim; Lyttle, Andrew

    2006-01-01

    The aim of this study was to examine the inter-relationship between athlete morphology, equipment set-up and performance in elite sprint kayaking. Correlations applied to data from the 2000 Olympics were used to select the most important links between morphology and boat set-up--paddle grip width and foot-bar distance. Associations between body size and the above selected equipment set-ups were calculated using a Pearson correlation matrix, to facilitate the logical selection of independent variables as input for regression analyses. Significant (p < 0.01) regression equations were developed for the prediction of foot-bar distance (r2 = 0.589: standard error of estimate (SEE) = 4.48) and paddle grip width (r2 = 0.541: SEE = 3.08). Three national-standard sprint kayakers used their preferred set-up together with modifications of their predicted set-up, derived from Olympic data, to test performance tolerance in sprint kayaking. Mean coefficients of multiple determination over three trials for the three paddlers of 0.91, 0.91 and 0.92 for left paddle force, right paddle force, and paddle angle at water entry, respectively, were recorded when using their preferred set-up. These data showed that the paddlers produce consistent patterns of motion. The intervention of altering the boat set-up resulted in varying changes to boat speed. The mean preferred speed for the three paddlers of 4.47 m/s was reduced by 0.07 and 0.10 m/s when the above boat set-up was modified to a predicted and 'predicted plus one standard deviation'respectively. These changes in boat speed were the result of alterations in the mechanics of paddling technique.

  20. New large solar photocatalytic plant: set-up and preliminary results.

    PubMed

    Malato, S; Blanco, J; Vidal, A; Fernández, P; Cáceres, J; Trincado, P; Oliveira, J C; Vincent, M

    2002-04-01

    A European industrial consortium called SOLARDETOX has been created as the result of an EC-DGXII BRITE-EURAM-III-financed project on solar photocatalytic detoxification of water. The project objective was to develop a simple, efficient and commercially competitive water-treatment technology, based on compound parabolic collectors (CPCs) solar collectors and TiO2 photocatalysis, to make possible easy design and installation. The design, set-up and preliminary results of the main project deliverable, the first European industrial solar detoxification treatment plant, is presented. This plant has been designed for the batch treatment of 2 m3 of water with a 100 m2 collector-aperture area and aqueous aerated suspensions of polycrystalline TiO2 irradiated by sunlight. Fully automatic control reduces operation and maintenance manpower. Plant behaviour has been compared (using dichloroacetic acid and cyanide at 50 mg l(-1) initial concentration as model compounds) with the small CPC pilot plants installed at the Plataforma Solar de Almería several years ago. The first results with high-content cyanide (1 g l(-1)) waste water are presented and plant treatment capacity is calculated.

  1. Validation of a calibration set-up for radiosondes to fulfil GRUAN requirements

    NASA Astrophysics Data System (ADS)

    Sairanen, H.; Heinonen, M.; Högström, R.

    2015-10-01

    Interest in the precise measurement of water vapour in the upper-air is growing along with the consciousness of climate change. Because better knowledge of high altitude humidity levels improves the accuracy of climate models and weather forecasts, the Global Climate Observing System (GCOS) is putting more effort into the quality of these measurements. The GCOS established the Reference Upper-Air Network (GRUAN) and set the requirements for its measurements accuracy and traceability to the International System of Units (SI). To fulfil these requirements, improved radiosondes and methods to calibrate them are being developed. This paper presents a new calibration system for radiosondes based on mixing air flows from two independent dew-point generators. The system operates in the air temperature range down to  -80 °C. Our results show that the new calibration set-up is able to provide calibrations for radionsondes at the uncertainty level of 2% in terms of the water vapour mixing ratio as required by GRUAN. A complete calibration covering the whole temperature and humidity range lasts less than three days. Additionally, the apparatus provides an option to characterize the behaviour of a radiosonde in changing temperatures and water vapour concentrations.

  2. Heavy ion elastic recoil detection analysis set up for electronic sputtering studies

    NASA Astrophysics Data System (ADS)

    Ghosh, S.; Avasthi, D. K.; Tripathi, A.; Kabiraj, D.; Sugathan, P.; Chaudhary, G. K.; Barua, P.

    2006-04-01

    Heavy ion elastic recoil detection analysis (ERDA) set up with a large solid angle (greater than or similar to 4.8 msr) Delta E - E position-sensitive telescope detector is developed at Inter University Accelerator Centre as a dedicated facility for the study of electronic sputtering of thin films under swift heavy ion (SHI) irradiation. The detector consists of a gas ionization chamber (Delta E ) and a solid-state surface barrier detector ( E ) housed in a same assembly. The electronic sputtering yield (atoms/ion) is determined by analyzing on-line fluence-dependent ERDA data obtained from a variety of thin films. Large erosion (> 10 5 atoms/ion) of carbon from a-C:H by 150 MeV Ag 13+ ions, evolution of nitrogen (greater than or similar to 880 atoms/ion) from copper nitride and depletion of oxygen (greater than or similar to 1000 atoms/ion) from copper oxide film under 200 MeV Au 15+ ion impact are studied and reported in this work. The electronic sputtering of these materials is discussed on the basis of the thermal spike model of SHI and solid interaction.

  3. Reconstruction of climate and environmental changes in the Bornholm Basin during the last 6000 years, based on foraminiferal assemblages

    NASA Astrophysics Data System (ADS)

    Binczewska, Anna; Polovodova Asteman, Irina; Moros, Matthias; Sławińska, Joanna

    2016-04-01

    The Baltic Sea is the largest brackish sea in the world connected to the Atlantic Ocean through the narrow and shallow Danish Straits. The hydrography of the Baltic Sea is strongly dependent on inflows from the North Sea and its environmental conditions are influenced by meteorological and anthropogenic factors. To improve our understanding of the natural variability and forcing factors driving changes in the Baltic ecosystem, detailed analyses of palaeoecological archives are needed. Here we present a high-resolution study of foraminiferal assemblages together with sediment geochemistry (LOI, TOC, TIC, CNS) from a 8-m long gravity core (GC) and a 42-cm long multi core (MUC) taken in the Bornholm Basin in 2013. Both cores were investigated in order to reconstruct bottom water mass variability during the mid- and late Holocene. Cores were dated by AMS 14C (mostly on Macoma balthica shells), 210Pb and 137Cs. Age-model allowed us to place variability of foraminiferal assemblages in time and link them with the Holocene climate extremes and the Major Baltic Inflows (MBIs). High absolute abundances (ind./g wet sed.) of foraminifera are found within a core interval corresponding to the Dark Ages and the Medieval Warm Period (~AD 400-1200). The Little Ice Age is represented by rare to absent foraminiferal shells, while significant changes of foraminiferal abundances occur in the lower part of core(~ BC 2050-2995). The dominant species found in both cores are Cribroelphidium excavatum, C. excavatum f. clavatum, C. albiumbilicatum and C. incertum, all adapted to an ecologically unstable environment with high fluctuations of salinity and oxygen. The arenaceous species Reophax dentaliniformis strongly occurs at ~ AD 1450-1600, where calcareous species were rare. Presence of agglutinated foraminifera and prevailing small size of individuals in all studied material suggest bottom water undersaturation with respect to calcium carbonate. In the Baltic Sea, bottom waters

  4. How to set up a GIS program at a Minority University/College

    NASA Astrophysics Data System (ADS)

    Mannel, S.

    2008-12-01

    This presentation provides detailed ideas on how to set up a GIS program and how to develop it for maximum benefits in the areas of education, research, and community outreach. We draw our experience from setting up the GIS program at Oglala Lakota College (OLC), Pine Ridge Reservation in South Dakota and work at the University of the Virgin Islands. GIS can be useful in many fields and is inexpensive to set up. Native Americans applied science in the past and now embrace GIS technology for everyday decision making. This presentation shows the wide range of GIS applications using OLC's GIS program as an example. We present our educational activities, research and community outreach. This presentation will give detailed advice of what works (and what doesn't) and to promote geospatial technology to other tribal or non-tribal colleges and universities.

  5. Influence of the set-up on the recording of diffractive optical elements into photopolymers

    NASA Astrophysics Data System (ADS)

    Gallego, S.; Fernández, R.; Márquez, A.; Neipp, C.; Beléndez, A.; Pascual, I.

    2014-05-01

    Photopolymers are often used as a base of holographic memories displays. Recently the capacity of photopolymers to record diffractive optical elements (DOE's) has been demonstrated. To fabricate diffractive optical elements we use a hybrid setup that is composed by three different parts: LCD, optical system and the recording material. The DOE pattern is introduced by a liquid crystal display (LCD) working in the amplitude only mode to work as a master to project optically the DOE onto the recording material. The main advantage of this display is that permit us modify the DOE automatically, we use the electronics of the video projector to send the voltage to the pixels of the LCD. The LCD is used in the amplitude-mostly modulation regime by proper orientation of the external polarizers (P); then the pattern is imaged onto the material with an increased spatial frequency (a demagnifying factor of 2) by the optical system. The use of the LCD allows us to change DOE recorded in the photopolymer without moving any mechanical part of the set-up. A diaphragm is placed in the focal plane of the relay lens so as to eliminate the diffraction orders produced by the pixelation of the LCD. It can be expected that the final pattern imaged onto the recording material will be low filtered due to the finite aperture of the imaging system and especially due to the filtering process produced by the diaphragm. In this work we analyze the effect of the visibility achieved with the LCD and the high frequency cut-off due to the diaphragm in the final DOE recorded into the photopolymer. To simulate the recording we have used the fitted values parameters obtained for PVA/AA based photopolymers and the 3 dimensional models presented in previous works.

  6. Setting up and Running a Loss and Bereavement Support Group for Adults with Learning Disabilities

    ERIC Educational Resources Information Center

    Boyden, Paul; Freeman, Adele; Offen, Liz

    2010-01-01

    Following evidence based literature, the Birmingham Clinical Psychology Service for People with Learning Disabilities ran a Loss and Bereavement Psychotherapy Group. The group consisted of five adults with mild learning disabilities, who met for 8 consecutive weeks. This paper reports the process of setting up a bereavement group for people with…

  7. Worms Eat My Garbage. How To Set Up and Maintain a Worm Composting System. First Edition.

    ERIC Educational Resources Information Center

    Appelhof, Mary

    This book is a resource for parents and teachers who want to teach about recycling and composting by setting up and maintaining a worm composting system. It is designed to be a detailed yet simple manual of vermicomposting. The manual covers the basics of vermicomposting and answers such questions as where to store a composting container, what…

  8. Set up and Operation of Video Cassette Recorders or "...How Do I Work This Thing???"

    ERIC Educational Resources Information Center

    Alaska State Dept. of Education, Juneau.

    Designed to assist Alaskans in making optimum use of the LearnAlaska TV transmitter network, this booklet provides instructions for the operation and maintenance of videocassette recorders (VCRs). After a brief introduction, which lists state film library addresses for ordering an accompanying videocassette entitled "Set Up & Operation for VCRs…

  9. A Guide To Setting Up a Creative Art Experiences Program for Older Adults with Developmental Disabilities.

    ERIC Educational Resources Information Center

    Harlan, Jane E.

    This guide is intended to help agencies serving older adults with mental retardation and other developmental disabilities in setting up a relatively inexpensive creative art program. The first section presents a rationale for creative art experiences for this population and then provides specific information on program development, including…

  10. Students' Errors in Setting up Difference Quotients and Connections to Their Conceptions of Function

    ERIC Educational Resources Information Center

    Tang, Gail

    2012-01-01

    Although finding the limits of the difference quotients in the definitions of the derivative is troubling for many students, a difficulty that preceded this confusion was observed: students were not able to correctly set up the difference quotients as required in the definitions. The purpose of this study is to uncover student errors in setting up…

  11. Nurse-led clinics: 10 essential steps to setting up a service.

    PubMed

    Hatchett, Richard

    This article outlines 10 key steps for practitioners to consider when setting up and running a nurse-led clinic. It lays emphasis on careful planning, professional development and the need to audit and evaluate the service to ensure the clinic is measurably effective. PMID:19068891

  12. Astronaut Andrew M. Allen, mission commander, sets up systems for a television downlink on the

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 ONBOARD VIEW --- Astronaut Andrew M. Allen, mission commander, sets up systems for a television downlink on the flight deck of the Space Shuttle Columbia. Allen was joined by four other astronauts and an international payload specialist for more than 16 days of research aboard Columbia. The photograph was taken with a 70mm handheld camera.

  13. Setting Up a Library: How To Begin or Begin Again. CSLA Guide No. 1.

    ERIC Educational Resources Information Center

    Smith, Ruth S.

    Designed as a simple how-to guide, this handbook presents guidelines for setting up a church or synagogue library or revitalizing an existing one. The first of 10 sections, "Begin with a Purpose," advocates thinking about the goals of the library and putting them in writing. It includes two brief sample mission statements. The second, "Establish…

  14. The Use of Instructional and Motivational Self-Talk in Setting up a Physical Education Lesson

    ERIC Educational Resources Information Center

    Zourbanos, Nikos

    2013-01-01

    The main purpose of this article is to provide guidelines to physical educators for setting up a self-talk program during their lesson. The article briefly presents definitions of self-talk and research findings in sport and physical education to highlight the important benefits of positive self-talk in enhancing task performance. It also provides…

  15. How To Set Up Your Own Small Business. Volumes I-II and Overhead Transparencies.

    ERIC Educational Resources Information Center

    Fallek, Max

    This two-volume textbook and collection of overhead transparency masters is intended for use in a course in setting up a small business. The following topics are covered in the first volume: getting off to a good start, doing market research, forecasting sales, financing a small business, understanding the different legal needs of different types…

  16. Setting Up an SSR Program in the Foreign Language Classroom: Some Questions and Answers

    ERIC Educational Resources Information Center

    Greenewald, M. Jane

    1978-01-01

    A Sustained Silent Reading (SSR) program provides a way to upgrade reading instruction by stressing self-selection, independent practice, and the use of reading as a communication tool. Guidelines are offered for setting up SSR programs, a resource library, and scheduling SSR periods. (Author/SW)

  17. Setting up spaces for collaboration in industry between researchers from the natural and social sciences.

    PubMed

    Flipse, Steven M; van der Sanden, Maarten C A; Osseweijer, Patricia

    2014-03-01

    Policy makers call upon researchers from the natural and social sciences to collaborate for the responsible development and deployment of innovations. Collaborations are projected to enhance both the technical quality of innovations, and the extent to which relevant social and ethical considerations are integrated into their development. This could make these innovations more socially robust and responsible, particularly in new and emerging scientific and technological fields, such as synthetic biology and nanotechnology. Some researchers from both fields have embarked on collaborative research activities, using various Technology Assessment approaches and Socio-Technical Integration Research activities such as Midstream Modulation. Still, practical experience of collaborations in industry is limited, while much may be expected from industry in terms of socially responsible innovation development. Experience in and guidelines on how to set up and manage such collaborations are not easily available. Having carried out various collaborative research activities in industry ourselves, we aim to share in this paper our experiences in setting up and working in such collaborations. We highlight the possibilities and boundaries in setting up and managing collaborations, and discuss how we have experienced the emergence of 'collaborative spaces.' Hopefully our findings can facilitate and encourage others to set up collaborative research endeavours.

  18. 41 CFR 102-34.285 - Where can we obtain help in setting up a maintenance program?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Where can we obtain help in setting up a maintenance program? 102-34.285 Section 102-34.285 Public Contracts and Property... obtain help in setting up a maintenance program? For help in setting up a maintenance program,...

  19. 41 CFR 102-34.285 - Where can we obtain help in setting up a maintenance program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Where can we obtain help in setting up a maintenance program? 102-34.285 Section 102-34.285 Public Contracts and Property... obtain help in setting up a maintenance program? For help in setting up a maintenance program,...

  20. 41 CFR 102-34.285 - Where can we obtain help in setting up a maintenance program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Where can we obtain help in setting up a maintenance program? 102-34.285 Section 102-34.285 Public Contracts and Property... obtain help in setting up a maintenance program? For help in setting up a maintenance program,...

  1. 41 CFR 102-34.285 - Where can we obtain help in setting up a maintenance program?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Where can we obtain help in setting up a maintenance program? 102-34.285 Section 102-34.285 Public Contracts and Property... obtain help in setting up a maintenance program? For help in setting up a maintenance program,...

  2. 41 CFR 102-34.285 - Where can we obtain help in setting up a maintenance program?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Where can we obtain help in setting up a maintenance program? 102-34.285 Section 102-34.285 Public Contracts and Property... obtain help in setting up a maintenance program? For help in setting up a maintenance program,...

  3. Spatial and temporal habitat partitioning by zooplankton in the Bornholm Basin (central Baltic Sea)

    NASA Astrophysics Data System (ADS)

    Schulz, Jan; Peck, Myron A.; Barz, Kristina; Schmidt, Jörn Oliver; Hansen, Frank C.; Peters, Janna; Renz, Jasmin; Dickmann, Miriam; Mohrholz, Volker; Dutz, Jörg; Hirche, Hans-Jürgen

    2012-12-01

    The deep basins in the Baltic Sea such as the Bornholm Basin (BB) are subject to seasonal changes in the strength of physico-chemical stratification. These depth-related changes in key abiotic factors are strong drivers of habitat partitioning by the autochthonous zooplankton community. Species-specific ecophysiological preferences often result in both seasonal and inter-annual changes in vertical abundance that, when combined with depth-specific water currents, also lead to horizontal differences in spatial distribution. The present study documented the seasonal and depth-specific changes in the abundance and species composition of zooplankton in the BB based upon broad-scale survey data: 832 vertically-resolved (10 m) multinet samples collected at nine stations between March 2002 and May 2003. Changes in the zooplankton community were significantly correlated with changes in ambient hydrography. Each of five taxa (Bosmina coregoni maritima, Acartia spp., Pseudocalanus spp., Temora longicornis, Synchaeta spp.) contributed >10% to the zooplankton community composition. The appearance of cladocerans was mainly correlated with the phenology of thermocline development in the spring. The cladoceran B. coregoni maritima was a dominant member of this community during the warmest periods, preferring the surface waters above the thermocline. Copepods exhibited distinct, ontogenetic and seasonal changes in their distribution. The rotifers (Synchaeta sp.) were the most abundant zooplankton in May. Based on a multivariate approach and the evaluation of vertical distribution patterns, five major habitat utilisation modes were identified that were based, to a large extent, on the dynamics of thermal and haline stratification of the Baltic Sea. Our statistical analysis of one of the most thorough datasets collected on Baltic zooplankton in recent decades reveals some of the factors that make this stratified system highly dynamic with respect to the spatial overlap between

  4. Observations of near-bottom currents in Bornholm Basin, Slupsk Furrow and Gdansk Deep

    NASA Astrophysics Data System (ADS)

    Bulczak, A. I.; Rak, D.; Schmidt, B.; Beldowski, J.

    2016-06-01

    Dense bottom currents are responsible for transport of the salty inflow waters from the North Sea driving ventilation and renewal of Baltic deep waters. This study characterises dense currents in three deep locations of the Baltic Proper: Bornholm Basin (BB), Gdansk Basin (GB) and Slupsk Furrow (SF). These locations are of fundamental importance for the transport and pollution associated with chemical munitions deposited in BB and GB after 2nd World War. Of further importance the sub-basins are situated along the pathway of dense inflowing water.Current velocities were measured in the majority of the water column during regular cruises of r/v Oceania and r/v Baltica in 2001-2012 (38 cruises) by 307 kHz vessel mounted (VM), downlooking ADCP. Additionally, the high-resolution CTD and oxygen profiles were collected. Three moorings measured current velocity profiles in SF and GB over the summer 2012. In addition, temperature, salinity, oxygen and turbidity were measured at about 1 m above the bottom in GB. The results showed that mean current speed across the Baltic Proper was around 12 cm s-1 and the stronger flow was characteristic to the regions located above the sills, in the Bornholm and Slupsk Channels, reaching on average about 20 cm s-1. The results suggest that these regions are important for the inflow of saline waters into the eastern Baltic and are the areas of intense vertical mixing. The VM ADCP observations indicate that the average near-bottom flow across the basin can reach 35±6 cm s-1. The mooring observations also showed similar near-bottom flow velocities. However, they showed that the increased speed of the near-bottom layer occurred frequently in SF and GB during short time periods lasting for about few to several days or 10-20% of time. The observations showed that the bottom mixed layer occupies at least 10% of the water column and the turbulent mixing induced by near-bottom currents is likely to produce sediment resuspension and transport

  5. Setting up a Grid: A Guide for Beginners by a Beginner

    NASA Technical Reports Server (NTRS)

    Welch, Clara

    2003-01-01

    A simple compute grid can be constructed for under $ 1,000 with 5 computers on a LAN for the purpose of video compression from captured digital video to MPEG file format. The process for setting up this grid will be covered in detail, including the required operating systems and hardware, the required globus software, and the required video capture and compression software. Pitfalls encountered will be discussed, and the approximate timeline for a motivated but uninformed beginner. The installation, configuration, and operation of additional software that is needed test, measure and otherwise verify that the grid components are functioning as "advertised", will also be presented. This is a true life account for setting up a grid based on instructions in Chapters 9 and 10 of Introduction to Grid Computing with Globus.

  6. Development of a grinding-specific performance test set-up.

    PubMed

    Olesen, C G; Larsen, B H; Andresen, E L; de Zee, M

    2015-01-01

    The aim of this study was to develop a performance test set-up for America's Cup grinders. The test set-up had to mimic the on-boat grinding activity and be capable of collecting data for analysis and evaluation of grinding performance. This study included a literature-based analysis of grinding demands and a test protocol developed to accommodate the necessary physiological loads. This study resulted in a test protocol consisting of 10 intervals of 20 revolutions each interspersed with active resting periods of 50 s. The 20 revolutions are a combination of both forward and backward grinding and an exponentially rising resistance. A custom-made grinding ergometer was developed with computer-controlled resistance and capable of collecting data during the test. The data collected can be used to find measures of grinding performance such as peak power, time to complete and the decline in repeated grinding performance. PMID:25367077

  7. Setting up and using the autopatcher for automated intracellular neural recording in vivo

    PubMed Central

    Kodandaramaiah, Suhasa B.; Holst, Gregory L.; Wickersham, Ian R.; Singer, Annabelle C.; Franzesi, Giovanni Talei; McKinnon, Michael L.; Forest, Craig R.; Boyden, Edward S.

    2016-01-01

    Whole cell patch clamping in vivo is an important neuroscience technique that uniquely provides access to both supra-threshold spiking and sub-threshold synaptic events of single neurons in the brain. This article describes how to set up and use the autopatcher, a robot for automatically obtaining high yield and high quality whole cell patch clamp recordings in vivo. Following this protocol, a functional experimental rig for automated whole cell patch clamping can be set up in one week. High quality surgical preparation of mice takes approximately 1 hour, and each autopatching experiment can be carried out over periods lasting several hours. Autopatching should enable in vivo intracellular investigations to be accessible by a significant number of neuroscience labs, and enable labs already doing in vivo patch clamp to scale up their efforts by reducing training time for new lab members and increasing experimental durations by handling mentally intensive tasks automatically. PMID:26938115

  8. The urban boundary-layer field campaign in marseille (ubl/clu-escompte): set-up and first results

    NASA Astrophysics Data System (ADS)

    Mestayer, P.G.; Durand, P.; Augustin, P.; Bastin, S.; Bonnefond, J.-M.; Benech, B.; Campistron, B.; Coppalle, A.; Delbarre, H.; Dousset, B.; Drobinski, P.; Druilhet, A.; Frejafon, E.; Grimmond, C.S.B.; Groleau, D.; Irvine, M.; Kergomard, C.; Kermadi, S.; Lagouarde, J.-P.; Lemonsu, A.; Lohou, F.; Long, N.; Masson, V.; Moppert, C.; Noilhan, J.; Offerle, B.; Oke, T.R.; Pigeon, G.; Puygrenier, V.; Roberts, S.; Rosant, J.-M.; Sanid, F.; Salmond, J.; Talbaut, M.; Voogt, J.

    The UBL/CLU (urban boundary layer/couche limite urbaine) observation and modelling campaign is a side-project of the regional photochemistry campaign ESCOMPTE. UBL/CLU focuses on the dynamics and thermodynamics of the urban boundary layer of Marseille, on the Mediterranean coast of France. The objective of UBL/CLU is to document the four-dimensional structure of the urban boundary layer and its relation to the heat and moisture exchanges between the urban canopy and the atmosphere during periods of low wind conditions, from June 4 to July 16, 2001. The project took advantage of the comprehensive observational set-up of the ESCOMPTE campaign over the Berre-Marseille area, especially the ground-based remote sensing, airborne measurements, and the intensive documentation of the regional meteorology. Additional instrumentation was installed as part of UBL/CLU. Analysis objectives focus on (i) validation of several energy balance computational schemes such as LUMPS, TEB and SM2-U, (ii) ground truth and urban canopy signatures suitable for the estimation of urban albedos and aerodynamic surface temperatures from satellite data, (iii) high resolution mapping of urban land cover, land-use and aerodynamic parameters used in UBL models, and (iv) testing the ability of high resolution atmospheric models to simulate the structure of the UBL during land and sea breezes, and the related transport and diffusion of pollutants over different districts of the city. This paper presents initial results from such analyses and details of the overall experimental set-up.

  9. Air fluorescence efficiency measurements for AIRWATCH based mission: Experimental set-up

    SciTech Connect

    Biondo, B.; Catalano, O.; Celi, F.; Fazio, G.; Giarrusso, S.; La Rosa, G.; Mangano, A.; Bonanno, G.; Cosentino, R.; Di Benedetto, R.; Scuderi, S.; Richiusa, G.; Gregorio, A.

    1998-06-15

    In the framework of the AIRWATCH project we present an experimental set-up to measure the efficiency of the UV fluorescence production of the air using hard X-ray stimulus. The measures will be carried out at different pressure and temperature to emulate the same condition of the upper layers of the atmosphere where X-ray and gamma ray photons of Gamma Ray Bursts are absorbed.

  10. Broadband short pulse measurement by autocorrelation with a sum-frequency generation set-up

    SciTech Connect

    Glotin, F.; Jaroszynski, D.; Marcouille, O.

    1995-12-31

    Previous spectral and laser pulse length measurements carried out on the CLIO FEL at wavelength {lambda}=8.5 {mu}m suggested that very short light pulses could be generated, about 500 fs wide (FWHM). For these measurements a Michelson interferometer with a Te crystal, as a non-linear detector, was used as a second order autocorrelation device. More recent measurements in similar conditions have confirmed that the laser pulses observed are indeed single: they are not followed by other pulses distant by the slippage length N{lambda}. As the single micropulse length is likely to depend on the slippage, more measurements at different wavelengths would be useful. This is not directly possible with our actual interferometer set-up, based on a phase-matched non-linear crystal. However, we can use the broadband non-linear medium provided by one of our users` experiments: Sum-Frequency Generation over surfaces. With such autocorrelation set-up, interference fringes are no more visible, but this is largely compensated by the frequency range provided. First tests at 8 {mu}m have already been performed to validate the technic, leading to results similar to those obtained with our previous Michelson set-up.

  11. Load test set-up for the Airmass Sunburst Ultra-Light Aircraft

    NASA Technical Reports Server (NTRS)

    Krug, Daniel W.; Smith, Howard W.

    1993-01-01

    The purpose of this project was to set up, instrument, and test a Sunburst Ultra-Light aircraft. The intentions of the project were that the aircraft would need to be suspended from the test stand, leveled in the stand, the strain gauges tested and wired to the test equipment, and finally, the aircraft would be destroyed to obtain the failing loads. All jobs were completed, except for the destruction of the aircraft. This notebook shows the group's progress as these tasks were completed, and the following section attempts to explain the photographs in the notebook.

  12. [Approaches to setting up the Center for identification of exhumed bodies in Chechen Republic].

    PubMed

    Klevno, V A; Ivanov, P L

    2007-01-01

    The authors participated in the activity of a group of European experts who visited Moscow, Rostov-on-Don and Grozny in September 2005 to clarify situation with identification of exhumed unknown dead bodies of the civil population. The European experts recommend to set up Center for Identification in Chechen Republic (in Grozny). The authors propose to make DNA identification tests in the Russian Federation Center for Forensic Medical Evaluation in Moscow which has much experience and staff skilled in identification of unknown exhumed bodies and can solve the problem of genetic identification of unidentified bodies of people missed in the Chechen Republic more effectively.

  13. A practical tutorial to set up NMR diffusometry equipment: application to liquid crystals.

    PubMed

    Cifelli, M

    2014-10-01

    NMR diffusometry is nowadays a well-established and powerful technique to investigate molecular translation in fluid materials. Standard NMR diffusometry approaches are based on pulsed field gradients generated by specific hardware and specially designed NMR probes. Here, we present an alternative set-up that exploits the static gradient present in the fringe field of any commercial superconducting magnet. This stray field diffusometry technique can be particularly useful to study diffusional processes in fast-relaxing and slow-diffusing systems, such as thermotropic liquid crystals, ionic liquids and polymer melts. PMID:25042779

  14. The effect of different foot and hand set-up positions on backstroke start performance.

    PubMed

    de Jesus, Karla; de Jesus, Kelly; Abraldes, J Arturo; Mourão, Luis; Borgonovo-Santos, Márcio; Medeiros, Alexandre I A; Gonçalves, Pedro; Chainok, Phornpot; Fernandes, Ricardo J; Vaz, Mário A P; Vilas-Boas, João Paulo

    2016-11-01

    Foot and hand set-up position effects were analysed on backstroke start performance. Ten swimmers randomly completed 27 starts grouped in trials (n = 3) of each variation, changing foot (totally immersed, partially and totally emerged) and hand (lowest, highest horizontal and vertical) positioning. Fifteen cameras recorded kinematics, and four force plates collected hands and feet kinetics. Standardised mean difference and 95% confidence intervals were used. Variations with feet immersed have shown lower vertical centre of mass (CM) set-up position (0.16 m), vertical impulse exerted at the hands, horizontal and vertical impulse exerted at the feet (0.28, 0.41, 0.16 N/BW.s, respectively) than feet emerged with hands horizontal and vertically positioned. Most variations with feet partially emerged exhibited higher and lesser vertical impulse exerted at hands than feet immersed and emerged (e.g. vertical handgrip, 0.13, 0.15 N/BW.s, respectively). Variation with feet emerged and hands on the lowest horizontal handgrip depicted shorter horizontal (0.23, 0.26 m) and vertical CM positioning at flight (0.16, 0.15 m) than the highest horizontal and vertical handgrip, respectively. Start variations have not affected 15-m time. Variations with feet partially or totally emerged depicted advantages, but focusing on the entry and underwater biomechanics is relevant for a shorter start time.

  15. Set Up of an Automatic Water Quality Sampling System in Irrigation Agriculture

    PubMed Central

    Heinz, Emanuel; Kraft, Philipp; Buchen, Caroline; Frede, Hans-Georg; Aquino, Eugenio; Breuer, Lutz

    2014-01-01

    We have developed a high-resolution automatic sampling system for continuous in situ measurements of stable water isotopic composition and nitrogen solutes along with hydrological information. The system facilitates concurrent monitoring of a large number of water and nutrient fluxes (ground, surface, irrigation and rain water) in irrigated agriculture. For this purpose we couple an automatic sampling system with a Wavelength-Scanned Cavity Ring Down Spectrometry System (WS-CRDS) for stable water isotope analysis (δ2H and δ18O), a reagentless hyperspectral UV photometer (ProPS) for monitoring nitrate content and various water level sensors for hydrometric information. The automatic sampling system consists of different sampling stations equipped with pumps, a switch cabinet for valve and pump control and a computer operating the system. The complete system is operated via internet-based control software, allowing supervision from nearly anywhere. The system is currently set up at the International Rice Research Institute (Los Baños, The Philippines) in a diversified rice growing system to continuously monitor water and nutrient fluxes. Here we present the system's technical set-up and provide initial proof-of-concept with results for the isotopic composition of different water sources and nitrate values from the 2012 dry season. PMID:24366178

  16. Test set up description and performances for HAWAII-2RG detector characterization at ESTEC

    NASA Astrophysics Data System (ADS)

    Crouzet, P.-E.; ter Haar, J.; de Wit, F.; Beaufort, T.; Butler, B.; Smit, H.; van der Luijt, C.; Martin, D.

    2012-07-01

    In the frame work of the European Space Agency's Cosmic Vision program, the Euclid mission has the objective to map the geometry of the Dark Universe. Galaxies and clusters of galaxies will be observed in the visible and near-infrared wavelengths by an imaging and spectroscopic channel. For the Near Infrared Spectrometer instrument (NISP), the state-of-the-art HAWAII-2RG detectors will be used, associated with the SIDECAR ASIC readout electronic which will perform the image frame acquisitions. To characterize and validate the performance of these detectors, a test bench has been designed, tested and validated. This publication describes the pre-tests performed to build the set up dedicated to dark current measurements and tests requiring reasonably uniform light levels (such as for conversion gain measurements). Successful cryogenic and vacuum tests on commercial LEDs and photodiodes are shown. An optimized feed through in stainless steel with a V-groove to pot the flex cable connecting the SIDECAR ASIC to the room temperature board (JADE2) has been designed and tested. The test set up for quantum efficiency measurements consisting of a lamp, a monochromator, an integrating sphere and set of cold filters, and which is currently under construction will ensure a uniform illumination across the detector with variations lower than 2%. A dedicated spot projector for intra-pixel measurements has been designed and built to reach a spot diameter of 5 μm at 920nm with 2nm of bandwidth [1].

  17. The effect of different foot and hand set-up positions on backstroke start performance.

    PubMed

    de Jesus, Karla; de Jesus, Kelly; Abraldes, J Arturo; Mourão, Luis; Borgonovo-Santos, Márcio; Medeiros, Alexandre I A; Gonçalves, Pedro; Chainok, Phornpot; Fernandes, Ricardo J; Vaz, Mário A P; Vilas-Boas, João Paulo

    2016-11-01

    Foot and hand set-up position effects were analysed on backstroke start performance. Ten swimmers randomly completed 27 starts grouped in trials (n = 3) of each variation, changing foot (totally immersed, partially and totally emerged) and hand (lowest, highest horizontal and vertical) positioning. Fifteen cameras recorded kinematics, and four force plates collected hands and feet kinetics. Standardised mean difference and 95% confidence intervals were used. Variations with feet immersed have shown lower vertical centre of mass (CM) set-up position (0.16 m), vertical impulse exerted at the hands, horizontal and vertical impulse exerted at the feet (0.28, 0.41, 0.16 N/BW.s, respectively) than feet emerged with hands horizontal and vertically positioned. Most variations with feet partially emerged exhibited higher and lesser vertical impulse exerted at hands than feet immersed and emerged (e.g. vertical handgrip, 0.13, 0.15 N/BW.s, respectively). Variation with feet emerged and hands on the lowest horizontal handgrip depicted shorter horizontal (0.23, 0.26 m) and vertical CM positioning at flight (0.16, 0.15 m) than the highest horizontal and vertical handgrip, respectively. Start variations have not affected 15-m time. Variations with feet partially or totally emerged depicted advantages, but focusing on the entry and underwater biomechanics is relevant for a shorter start time. PMID:27268463

  18. A digital holography set-up for 3D vortex flow dynamics

    NASA Astrophysics Data System (ADS)

    Lebon, Benoît; Perret, Gaële; Coëtmellec, Sébastien; Godard, Gilles; Gréhan, Gérard; Lebrun, Denis; Brossard, Jérôme

    2016-06-01

    In the present paper, a digital in-line holography (DIH) set-up, with a converging beam, is used to take three-dimensional (3D) velocity measurements of vortices. The vortices are formed periodically at the edges of a submerged horizontal plate submitted to regular waves. They take the form of vortex filaments that extend from side to side of the channel. They undergo strongly three-dimensional instability mechanisms that remain very complicated to characterize experimentally. The experiments are performed in a 10 × 0.3 × 0.3 m3 wave flume. The DIH set-up is performed using a modulated laser diode emitting at the wavelength of 640 nm and a lensless CCD camera. The beam crosses the channel side to side. To reveal the flow dynamics, 30-μm hydrogen bubbles are generated at the edge of the plate to serve as tracers. Their locations are recorded on the holograms multiple times to access the dynamics of the flow. This method leads to an accuracy in the order of 100 μm on the axial location. Those measurements have been validated with stereo-PIV measurements. A very good agreement is found on time-averaged velocity fields between the two techniques.

  19. Methodological issues in setting up a surveillance system for birth defects in India.

    PubMed

    Suresh, Seshadri; Thangavel, Gurusamy; Sujatha, Jagadeesh; Indrani, Suresh

    2005-01-01

    India is undergoing an epidemiological transition--communicable diseases are on the decline due to better living conditions and healthcare delivery. On the other hand, the relative increase in the prevalence of non-communicable, chronic and genetic diseases threatens to be a public health problem in India. One such group of disorders is congenital malformations. Though several studies have been done on congenital malformations in India since the early 1960s, coinciding with the thalidomide tragedy in the West, no uniform methods are available for the surveillance of birth defects. Each study has come out with varying results, not only because of the geographic variation in birth defects but also due to the varying standards adopted by each study in data collection, case definition and other methodological issues. Setting up a mechanism to understand the extent and nature of birth defects would involve the creation of a birth defects registry. The goals and objectives of such a registry should be formulated before it is set up. There are three types of registries-descriptive, analytical and preventive. These can also be classified as population- or hospital-based. Whether a registry is population- or hospital-based depends largely on the movement of mothers for delivery, registration of vital events in an area defined by the programme, as well as the resources available to the registry. Data can be collected in a passive or active manner, which also depends on the resources available to the registry. Every registry should have its own working definition of eligible cases to be reported, depending on the diagnostic services available in that area, and multiple sources of information should be used to improve the ascertainment rate. All the diagnostic terms should be coded and the information collected should be stored in a well-constructed database, preferably a relational type. Registries must evaluate their methods of data collection periodically to estimate the

  20. Internal movement, set-up accuracy and margins for stereotactic body radiotherapy using a stereotactic body frame.

    PubMed

    Hansen, Anders T; Petersen, Jørgen B; Høyer, Morten

    2006-01-01

    The aim of this study was to evaluate the uncertainty of patient immobilization within the Elekta body frame (SBF) used for stereotactic body radiotherapy (SBRT) and to suggest margins sufficient to ensure dose coverage to the gross target volume (GTV). The study was based on the evaluation of repeated CT-scans of 30 patients treated by SBRT. The overall uncertainty was divided between uncertainty related to internal movement of the tumor and uncertainty in the patient set-up. Standard deviations of the overall tumor displacement were 2 mm, 3 mm and 4 mm in medial-lateral (m-l), anterior-posterior (a-p), and cranio-caudal (c-c) directions, respectively. In a model based on the data, an ellipsoid planned target volume (PTV) corresponding to the standard deviations in the orthogonal directions and a scaling factor, K defined a 3-dimentional (3-D) probability density. According to the model, a 90% probability of full dose coverage of the GTV was secured using margins of 9 mm (m-l), 9 mm (a-p) and 13 mm (c-c), respectively. The overall uncertainty was dominated by internal tumor movements whereas the set-up uncertainty of the patient in the SBF was less pronounced. It was concluded that the Elekta SBF is useful for immobilisation of patients for SBRT. However, due to internal movement conventional margins of 5 mm in m-l and a-p and 10 mm in the c-c directions may be insufficient for full dose coverage. PMID:16982562

  1. Suggested set-up and layout of instruments and equipment for advanced operative laparoscopy.

    PubMed

    Winer, W K; Lyons, T L

    1995-02-01

    Crucial elements that ensure the organization and smoothness of a laparoscopic procedure are clear communication among well-trained endoscopy team members, properly maintained equipment, and a sensible layout of the instruments. The team consists of the surgeon, surgical assistant, circulator, scrub nurse, laser nurse, and anesthesiologist. To promote continuity and interaction and to ensure a systematic, pleasant pace for laparoscopic procedures, the team should establish a specific routine, as well as set-up and layout of tables, equipment, and instruments. Key ingredients for advanced operative laparoscopy to be performed with optimum efficiency and effectiveness are the best organization and placement of the equipment, instrumentation, and team in a particular setting in the operating room. PMID:9050565

  2. Error control in the set-up of stereo camera systems for 3d animal tracking

    NASA Astrophysics Data System (ADS)

    Cavagna, A.; Creato, C.; Del Castello, L.; Giardina, I.; Melillo, S.; Parisi, L.; Viale, M.

    2015-12-01

    Three-dimensional tracking of animal systems is the key to the comprehension of collective behavior. Experimental data collected via a stereo camera system allow the reconstruction of the 3d trajectories of each individual in the group. Trajectories can then be used to compute some quantities of interest to better understand collective motion, such as velocities, distances between individuals and correlation functions. The reliability of the retrieved trajectories is strictly related to the accuracy of the 3d reconstruction. In this paper, we perform a careful analysis of the most significant errors affecting 3d reconstruction, showing how the accuracy depends on the camera system set-up and on the precision of the calibration parameters.

  3. Setting up a regulatory compliance standard in today`s economy

    SciTech Connect

    Colbert, R.R.

    1994-12-31

    The economy, particularly in California, has forced the regulated community to begin streamlining and re-organization. The focus of industry today is survival. This translates into a lean staff with the dilemma of implementing and maintaining regulatory compliance on a low budget. In some instances financial resources have been absolved. Such circumstances allow innovation to excel to its highest peak. Setting up a compliance standard for an organization will allow the organization to effectively manage regulatory programs. Such a standard will define the regulatory obligations of the organization, particularly recognizing when you have exceeded the requirements. Compliance standards are intended to breed consistency among staff, while confirming that regulatory requirements have been met (particularly valuable in the mist of an external inspection).

  4. Specific heat measurement set-up for quench condensed thin superconducting films.

    PubMed

    Poran, Shachaf; Molina-Ruiz, Manel; Gérardin, Anne; Frydman, Aviad; Bourgeois, Olivier

    2014-05-01

    We present a set-up designed for the measurement of specific heat of very thin or ultra-thin quench condensed superconducting films. In an ultra-high vacuum chamber, materials of interest can be thermally evaporated directly on a silicon membrane regulated in temperature from 1.4 K to 10 K. On this membrane, a heater and a thermometer are lithographically fabricated, allowing the measurement of heat capacity of the quench condensed layers. This apparatus permits the simultaneous thermal and electrical characterization of successively deposited layers in situ without exposing the deposited materials to room temperature or atmospheric conditions, both being irreversibly harmful to the samples. This system can be used to study specific heat signatures of phase transitions through the superconductor to insulator transition of quench condensed films. PMID:24880383

  5. Three axis vector magnet set-up for cryogenic scanning probe microscopy.

    PubMed

    Galvis, J A; Herrera, E; Guillamón, I; Azpeitia, J; Luccas, R F; Munuera, C; Cuenca, M; Higuera, J A; Díaz, N; Pazos, M; García-Hernandez, M; Buendía, A; Vieira, S; Suderow, H

    2015-01-01

    We describe a three axis vector magnet system for cryogenic scanning probe microscopy measurements. We discuss the magnet support system and the power supply, consisting of a compact three way 100 A current source. We obtain tilted magnetic fields in all directions with maximum value of 5T along z-axis and of 1.2T for XY-plane magnetic fields. We describe a scanning tunneling microscopy-spectroscopy (STM-STS) set-up, operating in a dilution refrigerator, which includes a new high voltage ultralow noise piezodrive electronics and discuss the noise level due to vibrations. STM images and STS maps show atomic resolution and the tilted vortex lattice at 150 mK in the superconductor β-Bi2Pd. We observe a strongly elongated hexagonal lattice, which corresponds to the projection of the tilted hexagonal vortex lattice on the surface. We also discuss Magnetic Force Microscopy images in a variable temperature insert.

  6. Specific heat measurement set-up for quench condensed thin superconducting films.

    PubMed

    Poran, Shachaf; Molina-Ruiz, Manel; Gérardin, Anne; Frydman, Aviad; Bourgeois, Olivier

    2014-05-01

    We present a set-up designed for the measurement of specific heat of very thin or ultra-thin quench condensed superconducting films. In an ultra-high vacuum chamber, materials of interest can be thermally evaporated directly on a silicon membrane regulated in temperature from 1.4 K to 10 K. On this membrane, a heater and a thermometer are lithographically fabricated, allowing the measurement of heat capacity of the quench condensed layers. This apparatus permits the simultaneous thermal and electrical characterization of successively deposited layers in situ without exposing the deposited materials to room temperature or atmospheric conditions, both being irreversibly harmful to the samples. This system can be used to study specific heat signatures of phase transitions through the superconductor to insulator transition of quench condensed films.

  7. Three axis vector magnet set-up for cryogenic scanning probe microscopy

    SciTech Connect

    Galvis, J. A.; Herrera, E.; Buendía, A.; Guillamón, I.; Vieira, S.; Suderow, H.; Azpeitia, J.; Luccas, R. F.; Munuera, C.; García-Hernandez, M.; and others

    2015-01-15

    We describe a three axis vector magnet system for cryogenic scanning probe microscopy measurements. We discuss the magnet support system and the power supply, consisting of a compact three way 100 A current source. We obtain tilted magnetic fields in all directions with maximum value of 5T along z-axis and of 1.2T for XY-plane magnetic fields. We describe a scanning tunneling microscopy-spectroscopy (STM-STS) set-up, operating in a dilution refrigerator, which includes a new high voltage ultralow noise piezodrive electronics and discuss the noise level due to vibrations. STM images and STS maps show atomic resolution and the tilted vortex lattice at 150 mK in the superconductor β-Bi{sub 2}Pd. We observe a strongly elongated hexagonal lattice, which corresponds to the projection of the tilted hexagonal vortex lattice on the surface. We also discuss Magnetic Force Microscopy images in a variable temperature insert.

  8. Setting up your own business. Facing the future as an entrepreneur.

    PubMed

    Brent, N J

    1990-01-01

    Other areas of setting up and running a business also are important to explore, especially if the business plans to use employees. You will become an employer, and you must be familiar with rules and regulations that include areas such as the employee's right to a safe workplace, worker's compensation laws, unemployment compensation laws and tax liabilities, antidiscrimination laws, and wage and tax laws. If independent contractors are going to be used, you must recognize that well-developed contracts are a necessity. If you are going to market a new product, consult with an attorney whose practice concentrates in trademark and patent law before the product is shared with others. Being well informed about the proposed business venture, not only before its establishment but as it develops and grows, can help you be in the best position to have a successful business. PMID:2301936

  9. Three axis vector magnet set-up for cryogenic scanning probe microscopy.

    PubMed

    Galvis, J A; Herrera, E; Guillamón, I; Azpeitia, J; Luccas, R F; Munuera, C; Cuenca, M; Higuera, J A; Díaz, N; Pazos, M; García-Hernandez, M; Buendía, A; Vieira, S; Suderow, H

    2015-01-01

    We describe a three axis vector magnet system for cryogenic scanning probe microscopy measurements. We discuss the magnet support system and the power supply, consisting of a compact three way 100 A current source. We obtain tilted magnetic fields in all directions with maximum value of 5T along z-axis and of 1.2T for XY-plane magnetic fields. We describe a scanning tunneling microscopy-spectroscopy (STM-STS) set-up, operating in a dilution refrigerator, which includes a new high voltage ultralow noise piezodrive electronics and discuss the noise level due to vibrations. STM images and STS maps show atomic resolution and the tilted vortex lattice at 150 mK in the superconductor β-Bi2Pd. We observe a strongly elongated hexagonal lattice, which corresponds to the projection of the tilted hexagonal vortex lattice on the surface. We also discuss Magnetic Force Microscopy images in a variable temperature insert. PMID:25638089

  10. How To Set Up Your Own Small Business. Service Company Case Study. Manufacturing Firm Case Study. Retail Store Case Study.

    ERIC Educational Resources Information Center

    Fallek, Max

    This collection of case studies is intended for use in a course in setting up a small business. The first, a case study of the process of setting up a service company, covers analyzing the pros and cons of starting one's own business, assessing the competition and local market, and selecting a site for and financing the business. The principal…

  11. The experimental set-up of the RIB in-flight facility EXOTIC

    NASA Astrophysics Data System (ADS)

    Pierroutsakou, D.; Boiano, A.; Boiano, C.; Di Meo, P.; La Commara, M.; Manea, C.; Mazzocco, M.; Nicoletto, M.; Parascandolo, C.; Signorini, C.; Soramel, F.; Strano, E.; Toniolo, N.; Torresi, D.; Tortone, G.; Anastasio, A.; Bettini, M.; Cassese, C.; Castellani, L.; Corti, D.; Costa, L.; De Fazio, B.; Galet, G.; Glodariu, T.; Grebosz, J.; Guglielmetti, A.; Molini, P.; Pontoriere, G.; Rocco, R.; Romoli, M.; Roscilli, L.; Sandoli, M.; Stroe, L.; Tessaro, M.; Zatti, P. G.

    2016-10-01

    We describe the experimental set-up of the Radioactive Ion Beam (RIB) in-flight facility EXOTIC consisting of: (a) two position-sensitive Parallel Plate Avalanche Counters (PPACs), dedicated to the event-by-event tracking of the produced RIBs and to time of flight measurements and (b) the new high-granularity compact telescope array EXPADES (EXotic PArticle DEtection System), designed for nuclear physics and nuclear astrophysics experiments employing low-energy light RIBs. EXPADES consists of eight ΔE -Eres telescopes arranged in a cylindrical configuration around the target. Each telescope is made up of two Double Sided Silicon Strip Detectors (DSSSDs) with a thickness of 40/60 μm and 300 μm for the ΔE and Eres layer, respectively. Additionally, eight ionization chambers were constructed to be used as an alternative ΔE stage or, in conjunction with the entire DSSSD array, to build up more complex triple telescopes. New low-noise multi-channel charge-sensitive preamplifiers and spectroscopy amplifiers, associated with constant fraction discriminators, peak-and-hold and Time to Amplitude Converter circuits were developed for the electronic readout of the ΔE stage. Application Specific Integrated Circuit-based electronics was employed for the treatment of the Eres signals. An 8-channel, 12-bit multi-sampling 50 MHz Analog to Digital Converter, a Trigger Supervisor Board for handling the trigger signals of the whole experimental set-up and an ad hoc data acquisition system were also developed. The performance of the PPACs, EXPADES and of the associated electronics was obtained offline with standard α calibration sources and in-beam by measuring the scattering process for the systems 17O+58Ni and 17O+208Pb at incident energies around their respective Coulomb barriers and, successively, during the first experimental runs with the RIBs of the EXOTIC facility.

  12. Portable and low cost fluorescence set-up for in-situ screening of Ochratoxin A.

    PubMed

    Bueno, Diana; Mishra, Rupesh K; Hayat, Akhtar; Catanante, Gaëlle; Sharma, Vinay; Muñoz, Roberto; Marty, Jean-Louis

    2016-10-01

    The present article describes a portable and low cost fluorescence set-up designed and characterized for in-situ screening of Ochratoxin A (OTA) in cocoa samples at field settings. The sensing module (the set up) consists of a LED with the wavelength of 370-380nm and a color complementary metal oxide semiconductor (CMOS) micro-camera inbuilt at upright position of a black box to obtain an image of the sensing molecule. It allows the user to get an image of the sensing analytes under excitation conditions and process the image in order to predict the toxicity of the samples. The image capturing and processing of the system was based on the OTA concentration in the sample and analyzed data can be presented as RGB values. For each concentration of the OTA, the R, G, B co-ordinates were obtained and plotted to quantify actual OTA presents in the sample. Moreover, the system was tested for real sample analysis using cocoa contaminated with OTA. The system could detect OTA as low as 1.25ng/ml with the maximum recovery of 87.5% in cocoa samples. The OTA was extracted in 1% NaHCO3 and cleaned up using molecular imprinted polymer column (MIP). The method demonstrated a good linear range between 1.25 and 10ng/ml. The obtained results were cross validated using chromatographic method HPLC and also compared with commercially available fluorescence instrument. The developed fluorescence setup is simple, economical, and portable with added advantages of digital image processing. The system could be deployable to cocoa fields for monitoring of OTA in quick successions. It is noteworthy to mention that this is the first report of such portable fluorescence setup where, OTA sensing was explored.

  13. Quantum efficiency test set up performances for NIR detector characterization at ESTEC

    NASA Astrophysics Data System (ADS)

    Crouzet, P.-E.; Duvet, L.; De Wit, F.; Beaufort, T.; Blommaert, S.; Butler, B.; Van Duinkerken, G.; ter Haar, J.; Heijnen, J.; van der Luijt, K.; Smit, H.; Viale, T.

    2014-07-01

    The Payload Technology Validation Section (Future mission preparation Office) at ESTEC is in charge of specific mission oriented validation activities, for science and robotic exploration missions, aiming at reducing development risks in the implementation phase. These activities take place during the early mission phases or during the implementation itself. In this framework, a test set up to characterize the quantum efficiency of near infrared detectors has been developed. The first detector to be tested will an HAWAII-2RG detector with a 2.5μm cut off, it will be used as commissioning device in preparation to the tests of prototypes European detectors developed under ESA funding. The capability to compare on the same setup detectors from different manufacturers will be a unique asset for the future mission preparation office. This publication presents the performances of the quantum efficiency test bench to prepare measurements on the HAWAII-2RG detector. A SOFRADIR Saturn detector has been used as a preliminary test vehicle for the bench. A test set up with a lamp, chopper, monochromator, pinhole and off axis mirrors allows to create a spot of 1mm diameter between 700nm and 2.5μm.The shape of the beam has been measured to match the rms voltage read by the Merlin Lock -in amplifier and the amplitude of the incoming signal. The reference detectors have been inter-calibrated with an uncertainty up to 3 %. For the measurement with HAWAII-2RG detector, the existing cryostat [1] has been modified to adapt cold black baffling, a cold filter wheel and a sapphire window. An statistic uncertainty of +/-2.6% on the quantum efficiency on the detector under test measurement is expected.

  14. Setting up a STAR Tier 2 Site at Golias/Prague Farm

    NASA Astrophysics Data System (ADS)

    Chaloupka, Petr; Jakl, Pavel; Kapitán, Jan; Zerola, Michal; Lauret, Jérôme; STAR Collaboration

    2010-04-01

    High Energy Nuclear Physics (HENP) collaborations' experience show that the computing resources available at a single site are often neither sufficient nor satisfy the need of remote collaborators eager to carry their analysis in the fastest and most convenient way. From latencies in the network connectivity to the lack of interactivity, work at distant computing centers is often inefficient. Having fully functional software stack on local resources is a strong enabler of science opportunities for any local group who can afford the time investment. The situation becomes more complex as vast amount of data are often needed to perform meaningful analysis. Prague's heavy-ions group participating in STAR experiment at RHIC has been a strong advocate of local computing as the most efficient means of data processing and physics analyses. To create an environment where science can freely thrive, a Tier 2 computing center was set up at a Regional Computing Center for Particle Physics called "Golias". It is the biggest farm in the Czech Republic fully dedicated for particle physics experiments. We report on our experience in setting up a fully functional Tier 2 center leveraging the minimal locally available human and financial resources. We discuss the solutions chosen to address storage space and analysis issues and the impact on the farms overall functionality. This includes a locally built STAR analysis framework, integration with a local DPM system (a cost effective storage solution), the influence of the availability and quality of the network connection to Tier 0 via a dedicated CESNET/ESnet link and the development of light-weight yet fully automated data transfer tools allowing the movement of entire datasets from BNL (Tier 0) to Golias (Tier 2). We will summarize the impact of the gained computing performance on the efficiency of the local physics group at offline physics analysis and show the feasibility of such a solution that can used by other groups as well.

  15. Barriers for setting up a pulmonary rehabilitation program in the Eastern Province of Saudi Arabia

    PubMed Central

    Alsubaiei, Mohammed E.; Cafarella, Paul A.; Frith, Peter A.; McEvoy, R. Doug; Effing, Tanja W.

    2016-01-01

    BACKGROUND: Pulmonary rehabilitation (PR) programs proven to be one of the most effective treatment options for respiratory diseases; yet, they are not well-established in hospitals in Saudi Arabia. AIM: To determine the main barriers for setting up PR programs in Saudi Arabia. METHODS: A cross-sectional study was conducted in the Eastern Province of Saudi Arabia. Health care providers involved in treatment of chronic obstructive pulmonary disease (COPD) patients were recruited from 22 general government hospitals. Data were collected using questionnaires: Full version if they had heard about PR before the study, and a short version if they had not heard about PR before. RESULTS: A total of 123 health care providers were recruited (physicians [n = 44], nurses [n = 49], and respiratory therapists/technicians [n = 30]). Only 3.2% of the recruited health care providers had heard about PR programs before. According to the health care providers, the main barriers for setting up PR programs were a lack of (1) hospital capacity (75.6%), (2) trained health care providers (72.4%), and (3) funds (48.0%). There were significant differences in barriers reported by the health care providers. Compared to physicians, nurses were more likely to nominate the PR costs as a barrier (18.0% vs. 38.8%; P < 0.05). CONCLUSION: There is a worrisome lack of knowledge regarding content and benefits of PR programs among Saudi health care providers treating COPD patients. These findings imply that improving awareness and increasing education of the health care providers regarding PR will be required before PR can be more widely implemented as an integral treatment modality for patients with COPD in Saudi Arabia. PMID:27168860

  16. First Steps Toward a Motor Imagery Based Stroke BCI: New Strategy to Set up a Classifier.

    PubMed

    Kaiser, Vera; Kreilinger, Alex; Müller-Putz, Gernot R; Neuper, Christa

    2011-01-01

    A new approach in motor rehabilitation after stroke is to use motor imagery (MI). To give feedback on MI performance brain-computer interface (BCIs) can be used. This requires a fast and easy acquisition of a reliable classifier. Usually, for training a classifier, electroencephalogram (EEG) data of MI without feedback is used, but it would be advantageous if we could give feedback right from the beginning. The sensorimotor EEG changes of the motor cortex during active and passive movement (PM) and MI are similar. The aim of this study is to explore, whether it is possible to use EEG data from active or PM to set up a classifier for the detection of MI in a group of elderly persons. In addition, the activation patterns of the motor cortical areas of elderly persons were analyzed during different motor tasks. EEG was recorded from three Laplacian channels over the sensorimotor cortex in a sample of 19 healthy elderly volunteers. Participants performed three different tasks in consecutive order, passive, active hand movement, and hand MI. Classifiers were calculated with data of every task. These classifiers were then used to detect event-related desynchronization (ERD) in the MI data. ERD values, related to the different tasks, were calculated and analyzed statistically. The performance of classifiers calculated from passive and active hand movement data did not differ significantly regarding the classification accuracy for detecting MI. The EEG patterns of the motor cortical areas during the different tasks was similar to the patterns normally found in younger persons but more widespread regarding localization and frequency range of the ERD. In this study, we have shown that it is possible to use classifiers calculated with data from passive and active hand movement to detect MI. Hence, for working with stroke patients, a physiotherapy session could be used to obtain data for classifier set up and the BCI-rehabilitation training could start immediately.

  17. Portable and low cost fluorescence set-up for in-situ screening of Ochratoxin A.

    PubMed

    Bueno, Diana; Mishra, Rupesh K; Hayat, Akhtar; Catanante, Gaëlle; Sharma, Vinay; Muñoz, Roberto; Marty, Jean-Louis

    2016-10-01

    The present article describes a portable and low cost fluorescence set-up designed and characterized for in-situ screening of Ochratoxin A (OTA) in cocoa samples at field settings. The sensing module (the set up) consists of a LED with the wavelength of 370-380nm and a color complementary metal oxide semiconductor (CMOS) micro-camera inbuilt at upright position of a black box to obtain an image of the sensing molecule. It allows the user to get an image of the sensing analytes under excitation conditions and process the image in order to predict the toxicity of the samples. The image capturing and processing of the system was based on the OTA concentration in the sample and analyzed data can be presented as RGB values. For each concentration of the OTA, the R, G, B co-ordinates were obtained and plotted to quantify actual OTA presents in the sample. Moreover, the system was tested for real sample analysis using cocoa contaminated with OTA. The system could detect OTA as low as 1.25ng/ml with the maximum recovery of 87.5% in cocoa samples. The OTA was extracted in 1% NaHCO3 and cleaned up using molecular imprinted polymer column (MIP). The method demonstrated a good linear range between 1.25 and 10ng/ml. The obtained results were cross validated using chromatographic method HPLC and also compared with commercially available fluorescence instrument. The developed fluorescence setup is simple, economical, and portable with added advantages of digital image processing. The system could be deployable to cocoa fields for monitoring of OTA in quick successions. It is noteworthy to mention that this is the first report of such portable fluorescence setup where, OTA sensing was explored. PMID:27474323

  18. Set Up of an Automatic Water Quality Sampling System in Irrigation Agriculture

    NASA Astrophysics Data System (ADS)

    Heinz, Emanuel; Kraft, Philipp; Buchen, Caroline; Frede, Hans-Georg; Aquino, Eugenio; Breuer, Lutz

    2014-05-01

    Climate change has already a large impact on the availability of water resources. Many regions in South-East Asia are assumed to receive less water in the future, dramatically impacting the production of the most important staple food: rice (Oryza sativa L.). Rice is the primary food source for nearly half of the World's population, and is the only cereal that can grow under wetland conditions. Especially anaerobic (flooded) rice fields require high amounts of water but also have higher yields than aerobic produced rice. In the past different methods were developed to reduce the water use in rice paddies, like alternative wetting and drying or the use of mixed cropping systems with aerobic (non-flooded) rice and alternative crops such as maize. A more detailed understanding of water and nutrient cycling in rice-based cropping systems is needed to reduce water use, and requires the investigation of hydrological and biochemical processes as well as transport dynamics at the field scale. New developments in analytical devices permit monitoring parameters at high temporal resolutions and at acceptable costs without much necessary maintenance or analysis over longer periods. Here we present a new type of automatic sampling set-up that facilitates in situ analysis of hydrometric information, stable water isotopes and nitrate concentrations in spatially differentiated agricultural fields. The system facilitates concurrent monitoring of a large number of water and nutrient fluxes (ground, surface, irrigation and rain water) in irrigated agriculture. For this purpose we couple an automatic sampling system with a Wavelength-Scanned Cavity Ring Down Spectrometry System (WS-CRDS) for stable water isotope analysis (δ2H and δ18O), a reagentless hyperspectral UV photometer for monitoring nitrate content and various water level sensors for hydrometric information. The whole system is maintained with special developed software for remote control of the system via internet. We

  19. Straight ladder inclined angle in a field environment: the relationship among actual angle, method of set-up and knowledge

    PubMed Central

    Chang, Wen-Ruey; Huang, Yueng-Hsiang; Chang, Chien-Chi; Brunette, Christopher; Fallentin, Nils

    2016-01-01

    Abstract Ladder inclined angle is a critical factor that could lead to a slip at the base of portable straight ladders, a major cause of falls from heights. Despite several methods established to help workers achieve the recommended 75.5° angle for ladder set-up, it remains unclear if these methods are used in practice. This study explored ladder set-up behaviours in a field environment. Professional installers of a company in the cable and other pay TV industry were observed for ladder set-up at their worksites. The results showed that the actual angles of 265 ladder set-ups by 67 participants averaged 67.3° with a standard deviation of 3.22°. Although all the participants had training on recommended ladder set-up methods, only 3 out of 67 participants applied these methods in their daily work and even they failed to achieve the desired 75.5° angle. Therefore, ladder set-up remains problematic in real-world situations. Practitioner Summary: Professional installers of a cable company were observed for portable straight ladder set-up at their worksites. The ladder inclined angle averaged 67.3° with a standard deviation of 3.22°, while the recommended angle is 75.5°. Only a few participants used the methods that they learned during training in their daily work. PMID:26672809

  20. Straight ladder inclined angle in a field environment: the relationship among actual angle, method of set-up and knowledge.

    PubMed

    Chang, Wen-Ruey; Huang, Yueng-Hsiang; Chang, Chien-Chi; Brunette, Christopher; Fallentin, Nils

    2016-08-01

    Ladder inclined angle is a critical factor that could lead to a slip at the base of portable straight ladders, a major cause of falls from heights. Despite several methods established to help workers achieve the recommended 75.5° angle for ladder set-up, it remains unclear if these methods are used in practice. This study explored ladder set-up behaviours in a field environment. Professional installers of a company in the cable and other pay TV industry were observed for ladder set-up at their worksites. The results showed that the actual angles of 265 ladder set-ups by 67 participants averaged 67.3° with a standard deviation of 3.22°. Although all the participants had training on recommended ladder set-up methods, only 3 out of 67 participants applied these methods in their daily work and even they failed to achieve the desired 75.5° angle. Therefore, ladder set-up remains problematic in real-world situations. Practitioner Summary: Professional installers of a cable company were observed for portable straight ladder set-up at their worksites. The ladder inclined angle averaged 67.3° with a standard deviation of 3.22°, while the recommended angle is 75.5°. Only a few participants used the methods that they learned during training in their daily work.

  1. A set-up for a biased electrode experiment in ADITYA Tokamak

    NASA Astrophysics Data System (ADS)

    Dhyani, Pravesh; Ghosh, Joydeep; Sathyanarayana, K.; Praveenlal, V. E.; Gautam, Pramila; Shah, Minsha; Tanna, R. L.; Kumar, Pintu; Chavda, C.; Patel, N. C.; Panchal, V.; Gupta, C. N.; Jadeja, K. A.; Bhatt, S. B.; Kumar, S.; Raju, D.; Atrey, P. K.; Joisa, S.; Chattopadhyay, P. K.; Saxena, Y. C.

    2014-10-01

    An experimental set-up to investigate the effect of a biased electrode introduced in the edge region on ADITYA tokamak discharges is presented. A specially designed double-bellow mechanical assembly is fabricated for controlling the electrode location as well as its exposed length inside the plasma. The cylindrical molybdenum electrode is powered by a capacitor-bank based pulsed power supply (PPS) using a semiconductor controlled rectifier (SCR) as a switch with forced commutation. A Langmuir probe array for radial profile measurements of plasma potential and density is fabricated and installed. Standard results of improvement of global confinement have been obtained using a biased electrode. In addition to that, in this paper we show for the first time that the same biasing system can be used to avoid disruptions through stabilisation of magnetohydrodynamic (MHD) modes. Real time disruption control experiments have also been carried out by triggering the bias-voltage on the electrode automatically when the Mirnov probe signal exceeds a preset threshold value using a uniquely designed electronic comparator circuit. Most of the results related to the improved confinement and disruption mitigation are obtained in case of the electrode tip being kept at ~3 cm inside the last closed flux surface (LCFS) with an exposed length of ~20 mm in typical discharges of ADITYA tokamak.

  2. [Set up of a protocol for heparin use in special patients].

    PubMed

    Manresa Ramón, N; Nájera Pérez, Ma D; Page del Pozo, Ma Ángeles; Sánchez Martínez, I; Sánchez Catalicio, Ma del M; Roldán Schilling, V

    2014-04-01

    Low-molecular weight (LMW) heparins bring a series of advantages as compared to non-fractionated heparin (NFH), such as safety, efficacy, bioavailability, fewer monitoring, and persistent anti-coagulant response. There exist, however, a concern about their use in particular patients that may require a special control, such as those with renal failure, age over 75 years, obesity, and pregnancy. The aim of this study was the set up between the department of Pharmacy, Hematology, and Internal Medicine of a consensus protocol for the follow-up ad monitoring of LMWH in patients requiring a special control. For this purpose, we carried out a bibliographical review of the different heparins used under de above mentioned conditions. Based on the evidence available and the consensus among the members of the working group, we established a protocol that contained recommendations on prophylaxis, management and monitoring by means of the determination of anti-Xa factor. Besides, we included some clues on the therapeutic figures of anti-Xa and administration schedules for obtaining anti-Xa values within the range. Enoxaparin was the selected heparin given the evidence and its availability at our center.

  3. Ultra-sensitive γ-ray spectroscopy set-up for investigating primordial lithium problem

    NASA Astrophysics Data System (ADS)

    Gervino, G.; Gustavino, C.; Trezzi, D.; Aliotta, M.; Anders, M.; Boeltzig, A.; Bemmerer, D.; Best, A.; Broggini, C.; Bruno, C.; Caciolli, A.; Cavanna, F.; Corvisiero, P.; Davinson, T.; Depalo, R.; DiLeva, A.; Elekes, Z.; Ferraro, F.; Formicola, A.; Fülöp, Zs.; Guglielmetti, A.; Gyürky, Gy.; Imbriani, G.; Junker, M.; Menegazzo, R.; Prati, P.; Scott, D. A.; Straniero, O.; Szücs, T.

    2016-07-01

    To precisely determine BBN 6Li production, the cross-section of the nuclear reaction 2H(α, γ)6Li must be directly measured within the astrophysical energy range of 30-400 keV. This measure requires an ultra-low γ-ray background in the experimental set-up. We have realized the conditions matching these very strict requirements at LUNA, the deep underground accelerator laboratory active in the INFN Gran Sasso National Laboratory (LNGS), Italy: the γ-ray spectrometer background has been reduced down to reach unmatched low levels, comparable to the good ones experienced in dedicated off-line underground ultra low γ counting rate. We present and discuss the γ-ray background reduction reached in the HpGe spectrometer, where most of the remaining γ-ray background seen in the spectra are coming from the energetic deuterons scattered in the gas target by the α beam. Thanks to the low neutron environmental background at LUNA, the effect of this weak flux of 2-3 MeV neutrons on HpGe detectors has been studied in details and the results are presented and discussed.

  4. Set-up and methods for SiPM Photo-Detection Efficiency measurements

    NASA Astrophysics Data System (ADS)

    Zappalà, G.; Acerbi, F.; Ferri, A.; Gola, A.; Paternoster, G.; Zorzi, N.; Piemonte, C.

    2016-08-01

    In this work, a compact set-up and three different methods to measure the Photo-Detection Efficiency (PDE) of Silicon Photomultipliers (SiPMs) and Single-Photon Avalanche Diodes (SPADs) are presented. The methods, based on either continuous or pulsed light illumination, are discussed in detail and compared in terms of measurement precision and time. For the SiPM, these methods have the feature of minimizing the effect of both the primary and correlated noise on the PDE estimation. The PDE of SiPMs (produced at FBK, Trento, Italy) was measured in a range from UV to NIR, obtaining similar results with all the methods. Furthermore, the advantages of measuring, when possible, the PDE of SPADs (of the same technology and with the same layout of a single SiPM cell) instead of larger devices are also discussed and a direct comparison between measurement results is shown. Using a SPAD, it is possible to reduce the measurement complexity and uncertainty since the correlated noise sources are reduced with respect to the SiPM case.

  5. Carbon Ion Radiotherapy at the Gunma University Heavy Ion Medical Center: New Facility Set-up

    PubMed Central

    Ohno, Tatsuya; Kanai, Tatsuaki; Yamada, Satoru; Yusa, Ken; Tashiro, Mutsumi; Shimada, Hirofumi; Torikai, Kota; Yoshida, Yukari; Kitada, Yoko; Katoh, Hiroyuki; Ishii, Takayoshi; Nakano, Takashi

    2011-01-01

    Carbon ion radiotherapy (C-ion RT) offers superior dose conformity in the treatment of deep-seated tumors compared with conventional X-ray therapy. In addition, carbon ion beams have a higher relative biological effectiveness compared with protons or X-ray beams. C-ion RT for the first patient at Gunma University Heavy Ion Medical Center (GHMC) was initiated in March of 2010. The major specifications of the facility were determined based on the experience of clinical treatments at the National Institute of Radiological Sciences (NIRS), with the size and cost being reduced to one-third of those at NIRS. The currently indicated sites of cancer treatment at GHMC are lung, prostate, head and neck, liver, rectum, bone and soft tissue. Between March 2010 and July 2011, a total of 177 patients were treated at GHMC although a total of 100 patients was the design specification during the period in considering the optimal machine performance. In the present article, we introduce the facility set-up of GHMC, including the facility design, treatment planning systems, and clinical preparations. PMID:24213124

  6. Learning the hard way! Setting up an RCT of aromatherapy massage for patients with advanced cancer.

    PubMed

    Westcombe, A M; Gambles, M A; Wilkinson, S M; Barnes, K; Fellowes, D; Maher, E J; Young, T; Love, S B; Lucey, R A; Cubbin, S; Ramirez, A J

    2003-06-01

    Aromatherapy massage is used in cancer palliative care to improve quality of life but there is little evidence for its effectiveness. A large pragmatic multicentre randomized controlled trial was set up to examine the effectiveness of aromatherapy in improving psychological distress and quality of life in patients with cancer. This paper examines the challenges encountered in the design and execution of the study. The original design, i) focused on palliative care patients with advanced disease; ii) had both a no-intervention and a treatment control group (relaxation therapy); and iii) adopted 90% power for sample size calculations. A varied measurement strategy was employed. Recruitment proved difficult, referrers were 'gate-keeping', patients were often too ill to approach and others declined. The trial was modified to ensure viability. Eligibility was extended to all patients with cancer irrespective of stage, the relaxation group was removed and the power reduced to 80%. Although it is not generally good practice to change a study design once recruitment has started, the changes were consistent with the original basic study aims and design principles. The data collection phase was successfully completed in July 2002. PMID:12822844

  7. The new dedicated PIXE set-up at the National Environmental Research Institute, Denmark

    NASA Astrophysics Data System (ADS)

    Kemp, Kâre; Waahlin, Peter

    1999-06-01

    The Niels Bohr Institute in Copenhagen was in the beginning of the 70'es one of the early places for PIXE. Contributions were made to the theoretical interpretation of the PIXE spectra as well as the practical application. The home-made 4 MV van de Graaff accelerator at the Niels Bohr Institute was an excellent tool for PIXE. The accelerator, which was used for many years, has now found its place on a museum after more than 40 years of active service. A dedicated PIXE set-up has now been established at the National Environmental Research Institute using a new 1.7 MV Tandem Pelletron (5SDH) from NEC. The main application is elemental analysis of outdoor aerosols. The main work is unsophisticated macro analyses, which do not push the equipment to its limits. This enables automated analysis of about 10,000 samples per year using very limited manpower resources. The research focuses on the contribution from various source types to the atmosphere over Europe, the North Atlantic and Greenland. Source compositions and their temporal variations are studied.

  8. Twelve tips on how to set up postgraduate training via remote clinical supervision.

    PubMed

    Wearne, Susan; Dornan, Tim; Teunissen, Pim W; Skinner, Timothy

    2013-11-01

    Doctors-in-training can now be supervised remotely by specialist clinicians using information and communication technology. This provides an intermediate stage of professional development between on-site supervision and independent medical practice. Remote supervision could increase training capacity, particularly in underserved areas and ensure doctors are willing and able to practice where they are needed once qualified. Remotely supervised doctors learn via virtual autonomy in clinical decision making and working at the limits of their abilities. It suits experienced registrars with resilience, insight into their strengths and weaknesses, capacity to self-monitor and correct, and willingness to seek help. These doctors benefit from remote supervisors who facilitate their learning, monitor their well-being, and support them holistically. Educational organisations need to oversee remote placements and match the right registrar, to the right placement with the right supervisor. We outline in our twelve tips how to set up remote supervision in order to maximise the educational benefits and minimise the risks.

  9. Probabilistic multiscale image segmentation: set-up and first results (Proceedings Only)

    NASA Astrophysics Data System (ADS)

    Vincken, Koen L.; Koster, Andre S.; Viergever, Max A.

    1992-09-01

    We have developed a method to segment two- and three-dimensional images using a multiscale (hyperstack) approach with probabilistic linking. A hyperstack is a voxel-based multiscale data structure containing linkages between voxels at different scales. The scale-space is constructed by repeatedly applying a discrete convolution with a Gaussian kernel to the original input image. Between these levels of increasing scale we establish child-parent linkages according to a linkage scheme that is based on affection. In the resulting tree-like data structure roots are formed to indicate the most plausible locations in scale-space where objects (of different sizes) are actually defined by a single voxel. Tracing the linkages back from every root to the ground level produces a segmented image. The present paper deals with probabilistic linking, i.e., a set-up in which a child voxel can be linked to more than one parent voxel. The output of the thus constructed hyperstack -- a list of object probabilities per voxel -- can be directly related to the opacities used in volume renderers.

  10. The influence of the IMRT QA set-up error on the 2D and 3D gamma evaluation method as obtained by using Monte Carlo simulations

    NASA Astrophysics Data System (ADS)

    Kim, Kyeong-Hyeon; Kim, Dong-Su; Kim, Tae-Ho; Kang, Seong-Hee; Cho, Min-Seok; Suh, Tae Suk

    2015-11-01

    The phantom-alignment error is one of the factors affecting delivery quality assurance (QA) accuracy in intensity-modulated radiation therapy (IMRT). Accordingly, a possibility of inadequate use of spatial information in gamma evaluation may exist for patient-specific IMRT QA. The influence of the phantom-alignment error on gamma evaluation can be demonstrated experimentally by using the gamma passing rate and the gamma value. However, such experimental methods have a limitation regarding the intrinsic verification of the influence of the phantom set-up error because experimentally measuring the phantom-alignment error accurately is impossible. To overcome this limitation, we aimed to verify the effect of the phantom set-up error within the gamma evaluation formula by using a Monte Carlo simulation. Artificial phantom set-up errors were simulated, and the concept of the true point (TP) was used to represent the actual coordinates of the measurement point for the mathematical modeling of these effects on the gamma. Using dose distributions acquired from the Monte Carlo simulation, performed gamma evaluations in 2D and 3D. The results of the gamma evaluations and the dose difference at the TP were classified to verify the degrees of dose reflection at the TP. The 2D and the 3D gamma errors were defined by comparing gamma values between the case of the imposed phantom set-up error and the TP in order to investigate the effect of the set-up error on the gamma value. According to the results for gamma errors, the 3D gamma evaluation reflected the dose at the TP better than the 2D one. Moreover, the gamma passing rates were higher for 3D than for 2D, as is widely known. Thus, the 3D gamma evaluation can increase the precision of patient-specific IMRT QA by applying stringent acceptance criteria and setting a reasonable action level for the 3D gamma passing rate.

  11. Bushmeat genetics: setting up a reference framework for the DNA typing of African forest bushmeat.

    PubMed

    Gaubert, Philippe; Njiokou, Flobert; Olayemi, Ayodeji; Pagani, Paolo; Dufour, Sylvain; Danquah, Emmanuel; Nutsuakor, Mac Elikem K; Ngua, Gabriel; Missoup, Alain-Didier; Tedesco, Pablo A; Dernat, Rémy; Antunes, Agostinho

    2015-05-01

    The bushmeat trade in tropical Africa represents illegal, unsustainable off-takes of millions of tons of wild game - mostly mammals - per year. We sequenced four mitochondrial gene fragments (cyt b, COI, 12S, 16S) in >300 bushmeat items representing nine mammalian orders and 59 morphological species from five western and central African countries (Guinea, Ghana, Nigeria, Cameroon and Equatorial Guinea). Our objectives were to assess the efficiency of cross-species PCR amplification and to evaluate the usefulness of our multilocus approach for reliable bushmeat species identification. We provide a straightforward amplification protocol using a single 'universal' primer pair per gene that generally yielded >90% PCR success rates across orders and was robust to different types of meat preprocessing and DNA extraction protocols. For taxonomic identification, we set up a decision pipeline combining similarity- and tree-based approaches with an assessment of taxonomic expertise and coverage of the GENBANK database. Our multilocus approach permitted us to: (i) adjust for existing taxonomic gaps in GENBANK databases, (ii) assign to the species level 67% of the morphological species hypotheses and (iii) successfully identify samples with uncertain taxonomic attribution (preprocessed carcasses and cryptic lineages). High levels of genetic polymorphism across genes and taxa, together with the excellent resolution observed among species-level clusters (neighbour-joining trees and Klee diagrams) advocate the usefulness of our markers for bushmeat DNA typing. We formalize our DNA typing decision pipeline through an expert-curated query database - DNA BUSHMEAT - that shall permit the automated identification of African forest bushmeat items.

  12. Potentials and Limitations of Guiding Liver Stereotactic Body Radiation Therapy Set-Up on Liver-Implanted Fiducial Markers

    SciTech Connect

    Wunderink, Wouter; Mendez Romero, Alejandra; Seppenwoolde, Yvette; Boer, Hans de; Levendag, Peter; Heijmen, Ben

    2010-08-01

    Purpose: We investigated the potentials and limitations of guiding liver stereotactic body radiation therapy (SBRT) set-up on liver-implanted fiducial markers. Methods and Materials: Twelve patients undergoing compression-supported SBRT in a stereotactic body frame received fluoroscopy at treatment preparation and before each treatment fraction. In fluoroscopic videos we localized the markers and diaphragm tip at expiration and the spine (measurements on free-breathing and abdominal compression). Day-to-day displacements, rotations (markers only), and deformations were determined. Marker guidance was compared to conventional set-up strategies in treatment set-up simulations. Results: For compression, day-to-day motion of markers with respect to their centers of mass (COM) was {sigma} = 0.9 mm (random error SD), {Sigma} = 0.4 mm (systematic error SD), and <2.1 mm (maximum). Consequently, assuming that markers were closely surrounding spherical tumors, marker COM-guided set-up would have required safety margins of {approx}2 mm. Using marker COM as the gold standard, other set-up methods (using no correction, spine registration, and diaphragm tip craniocaudal registration) resulted in set-up errors of 1.4 mm < {sigma} < 2.8 mm, 2.6 mm < {Sigma} < 5.1 mm, and 6.3 mm < max < 12.4 mm. Day-to-day intermarker motion of <16.7%, 2.2% median, and rotations between 3.5{sup o} and 7.2{sup o} were observed. For markers not surrounding the tumor, e.g., 5 cm between respective COMs, these changes could effect residual tumor set-up errors up to 8.4 mm, 1.1 mm median (deformations), and 3.1 mm to 6.3 mm (rotations). Compression did not systematically contribute to deformations and rotations, since similar results were observed for free-breathing. Conclusions: If markers can be implanted near and around the tumor, residual set-up errors by marker guidance are small compared to those of conventional set-up methods, allowing high-precision tumor radiation set-up. However, substantial

  13. In vitro investigations of repulsion during laser lithotripsy using a pendulum set-up.

    PubMed

    Sroka, Ronald; Haseke, Nicolas; Pongratz, Thomas; Hecht, Volkmar; Tilki, Derya; Stief, Christian G; Bader, Markus Jürgen

    2012-05-01

    Ureteroscopic laser lithotripsy is a commonly used technique to treat ureteral calculi.The type of energy source used is one of the main influences of retrograd calculi propulsion. Using a momentum pendulum under-water set-up the induced momentum and the initial velocity were investigated. Pulsed laser light from three different clinically available laser systems, including a Ho:YAG laser, a frequency-doubled double-pulse (second harmonic generation, SHG) Nd:YAG laser and a flash-lamp pumped dye (FLPD) laser, were transmitted via flexible fibres of different core diameter to the front of the pendulum sinker. Single pulses at variable pulse energy, according to the clinical laser parameter settings, were applied to the target sinker, thus causing a repulsion-induced deflection which was documented by video recording. The maximum deflection was determined. Solving the differential equation of a pendulum gives the initial velocity, the laser-induced momentum and the efficiency of momentum transfer. The induced deflection as well as the starting velocity of the two short-duration pulsed laser systems (SHG Nd:YAG, FLPD) were similar (s (max) = 2-3.6 cm and v (0) = 150-200 mm/s, respectively), whereas both values were lower using the Ho:YAG laser with a long pulse duration (s (max) = 0.9--1.6 cm and v (0) = 60-105 mm/s, respectively). The momentum I induced by the Ho:YAG laser was only 50% and its transfer efficacy η (Repuls) was reduced to less than 5% of the values of the two short-pulsed laser systems. This investigation clearly showed the variable parts and amounts of repulsion using different pulsed lasers in an objective and reproducible manner. The momentum transfer efficiency could be determined without any physical friction problems. Further investigations are needed to compare stone fragmentation techniques with respect to laser repulsion and its clinical impact.

  14. How to set-up a program of minimally-invasive surgery for congenital heart defects

    PubMed Central

    Pérez-Caballero, Ramón; Pita-Fernández, Ana; González-López, María-Teresa; Sánchez, Jairo; De Agustín, Juan-Carlos

    2016-01-01

    Background Mid-line sternotomy is the commonest incision for cardiac surgery. Alternative approaches are becoming fashionable in many centres, amidst some reluctance because of learning curves and overall complexity. Our recent experience in starting a new program on minimally invasive pediatric cardiac surgery is presented. The rationale for a stepwise onset and the short-medium term results for a three-year span are displayed. Methods A three-step schedule is planned: First, an experienced surgeon (A) starts performing simple cases. Second, new surgeons (B, C, D, E) are introduced to the minimally invasive techniques according to their own proficiency and skills. Third, the new adopters are enhanced to suggest and develop further minimally invasive approaches. Two quality markers are defined: conversion rate and complications. Results In part one, surgeon A performs sub-mammary, axillary and lower mini-sternotomy approaches for simple cardiac defects. In part two, surgeons B, C, D and E are customly introduced to such incisions. In part three, new approaches such as upper mini-sternotomy, postero-lateral thoracotomy and video-assisted mini-thoracotomy are introduced after being suggested and developed by surgeons B, C and E, as well as an algorithm to match cardiac conditions and age/weight to a given alternative approach. The conversion rate is one out of 148 patients. Two major complications were recorded, none of them related to our alternative approach. Four minor complications linked to the new incision were registered. The minimally invasive to mid-line sternotomy ratio rose from 20% in the first year to 40% in the third year. Conclusions Minimally invasive pediatric cardiac surgery is becoming a common procedure worldwide. Our schedule to set up a program proves beneficial. The three-step approach has been successful in our experience, allowing a tailored training for every new surgeon and enhancing the enthusiasm in developing further strategies on their

  15. Influence of experimental set-up on the infiltration characteristics during managed aquifer recharge operation

    NASA Astrophysics Data System (ADS)

    Fichtner, Thomas; Vanzella de Melo, Julio Augusto; Stefan, Catalin

    2016-04-01

    The main focus during operation of managed aquifer recharge (MAR) is on clogging processes, specifically on the changes of infiltration capacities and degradation of infiltrated organic substances including vadose zone oxygen dynamics. Lab scale experiments are one opportunity to understand and characterize these processes under different drying and wetting cycles and infiltration rates. However, the multitude of assumptions and scale-related limitations of downscale investigations often lead to over- or underestimations, rendering their results useless when translated to field-like conditions. Therefore, the specific objective of this investigation is to compare the results obtained from two different experimental set-ups with different scales: a 3D, rectangular shaped, stainless steel lysimeter (1.5 x 1.0 x 1.0 m) with an infiltration basin installed in the centre of its surface and a 1D soil column (1m, ᴓ 0.15 m) with the infiltration over the complete column surface. The study focuses on the influence of the experimental setup conditions on the soil clogging, water flow pattern, oxygen dynamics and degradation of organic substances. The results should allow making statements about the suitability of these lab experiments for the investigation of processes taking place in the unsaturated soil zone during operation of MAR. Both experimental units were packed with the same soil and equipped with tensiometers, TDR-probes, oxygen probes and suction cups in two depths for the estimation of spatial and temporal distribution of soil moisture, oxygen and infiltrated substances. The lysimeter and the column were placed inside of a fully automatic climate tent, which facilitates the exact control of air temperature and humidity. The first results confirm that both infiltration units are suitable to simulate the clogging and the oxidation of easily degradable organic substances. However, the velocity of water transport is higher in the column compared with the lysimeter

  16. Different sedimentological and thermal evolution of three north-pyrenean basins during their set-up

    NASA Astrophysics Data System (ADS)

    Chelalou, Roman; Nalpas, Thierry; Bousquet, Romain; Lahfid, Abdeltif

    2015-04-01

    out to be good places where to study the evolution of passive margin analogue and also to be a good example where the sediments were metamorphosed during the basin set up.

  17. In vitro investigations of repulsion during laser lithotripsy using a pendulum set-up.

    PubMed

    Sroka, Ronald; Haseke, Nicolas; Pongratz, Thomas; Hecht, Volkmar; Tilki, Derya; Stief, Christian G; Bader, Markus Jürgen

    2012-05-01

    Ureteroscopic laser lithotripsy is a commonly used technique to treat ureteral calculi.The type of energy source used is one of the main influences of retrograd calculi propulsion. Using a momentum pendulum under-water set-up the induced momentum and the initial velocity were investigated. Pulsed laser light from three different clinically available laser systems, including a Ho:YAG laser, a frequency-doubled double-pulse (second harmonic generation, SHG) Nd:YAG laser and a flash-lamp pumped dye (FLPD) laser, were transmitted via flexible fibres of different core diameter to the front of the pendulum sinker. Single pulses at variable pulse energy, according to the clinical laser parameter settings, were applied to the target sinker, thus causing a repulsion-induced deflection which was documented by video recording. The maximum deflection was determined. Solving the differential equation of a pendulum gives the initial velocity, the laser-induced momentum and the efficiency of momentum transfer. The induced deflection as well as the starting velocity of the two short-duration pulsed laser systems (SHG Nd:YAG, FLPD) were similar (s (max) = 2-3.6 cm and v (0) = 150-200 mm/s, respectively), whereas both values were lower using the Ho:YAG laser with a long pulse duration (s (max) = 0.9--1.6 cm and v (0) = 60-105 mm/s, respectively). The momentum I induced by the Ho:YAG laser was only 50% and its transfer efficacy η (Repuls) was reduced to less than 5% of the values of the two short-pulsed laser systems. This investigation clearly showed the variable parts and amounts of repulsion using different pulsed lasers in an objective and reproducible manner. The momentum transfer efficiency could be determined without any physical friction problems. Further investigations are needed to compare stone fragmentation techniques with respect to laser repulsion and its clinical impact. PMID:22011742

  18. Novel Set-Up for Low-Disturbance Sampling of Volatile and Non-volatile Compounds from Plant Roots.

    PubMed

    Eilers, Elisabeth J; Pauls, Gerhard; Rillig, Matthias C; Hansson, Bill S; Hilker, Monika; Reinecke, Andreas

    2015-03-01

    Most studies on rhizosphere chemicals are carried out in substrate-free set-ups or in artificial substrates using sampling methods that require an air flow and may thus cause disturbance to the rhizosphere. Our study aimed to develop a simplified and inexpensive system that allows analysis of rhizosphere chemicals at experimentally less disturbed conditions. We designed a mesocosm in which volatile rhizosphere chemicals were sampled passively (by diffusion) without air- and water flow on polydimethylsiloxane-(PDMS) tubes. Dandelion (Taraxacum sect. ruderalia) was used as model plant; roots were left undamaged. Fifteen volatiles were retrieved from the sorptive material by thermal desorption for analysis by gas chromatography/mass spectrometry (GC/MS). Furthermore, three sugars were collected from the rhizosphere substrate by aqueous extraction and derivatized prior to GC/MS analysis. In order to study how the quantity of detected rhizosphere compounds depends on the type of soil or substrate, we determined the matrix-dependent recovery of synthetic rhizosphere chemicals. Furthermore, we compared sorption of volatiles on PDMS tubes with and without direct contact to the substrate. The results show that the newly designed mesocosm is suitable for low-invasive extraction of volatile and non-volatile compounds from rhizospheres. We further highlight how strongly the type of substrate and contact of PDMS tubes to the substrate affect the detectability of compounds from rhizospheres. PMID:25795090

  19. An experimental set-up to analyse the oxygen consumption of elastomers during ageing by using a differential oxygen analyser

    NASA Astrophysics Data System (ADS)

    Herzig, Alexander; Johlitz, Michael; Lion, Alexander

    2015-11-01

    Ageing of polymers becomes more and more important. This can be seen by the increasing number of research projects dealing with this topic. However, the influence of oxygen on changes in the mechanical performance is undisputable and important with respect to the lifetime of polymer products. Therefore, a respirometer offers the potential to detect the smallest amounts of oxygen changes in the polymers' ambient air. It will be used to analyse the oxygen consumption of rubber which is exposed for different times to elevated temperatures. In this contribution, virgin rubber samples are aged for various times in a sealed chamber at temperatures of 60, 80 and 100°C. The decline of the oxygen concentration in the ambient air is measured by flushing the chamber with dried and cleaned air which is conducted into the respirometer. The oxygen concentration is compared with that in a reference chamber, which is exposed to the same ageing conditions as the sample under investigation. The absorbed oxygen is relevant for ageing and a considerable factor for further investigations. For this reason, an experimental set-up using a differential oxygen analyser is developed, which allows for ageing several samples simultaneously in external climate chambers. The comparison of the change in the mechanical material behaviour after ageing can provide an important contribution for improving constitutive models or ongoing researches on the fatigue strength of polymers. This work shows the development of an improved method for combining mechanical testing and the measurement of oxygen consumption.

  20. Medium-term cost-effectiveness of an automated non-invasive ventilation outpatient set-up versus a standard fixed level non-invasive ventilation inpatient set-up in obese patients with chronic respiratory failure: a protocol description

    PubMed Central

    Mandal, S; Arbane, G; Murphy, P; Elliott, M W; Janssens, J P; Pepin, J L; Muir, J F; Cuvelier, A; Polkey, M; Parkin, D; Douiri, A; Hart, N

    2015-01-01

    Introduction Obesity is an escalating issue, with an accompanying increase in referrals of patients with obesity-related respiratory failure. Currently, these patients are electively admitted to hospital for initiation of non-invasive ventilation (NIV), but it is unknown whether outpatient initiation is as effective as inpatient set-up. We hypothesise that outpatient set-up using an autotitrating NIV device will be more cost-effective than a nurse-led inpatient titration and set-up. Methods and analysis We will undertake a multinational, multicentre randomised controlled trial. Participants will be randomised to receive the usual inpatient set-up, which will include nurse-led initiation of NIV or outpatient set-up with an automated NIV device. They will be stratified according to the trial site, gender and previous use of NIV or continuous positive airway pressure. Assuming a 10% dropout rate, a total sample of 82 patients will be required. Cost-effectiveness will be evaluated using standard treatment costs and health service utilisation as well as health-related quality of life measures (severe respiratory insufficiency (SRI) and EuroQol-5 dimensions (EQ-5D)). A change in the SRI questionnaire will be based on the analysis of covariance adjusting for the baseline measurements between the two arms of patients. Ethics and dissemination This study has been approved by the Westminster National Research Ethics Committee (11/LO/0414) and is the trial registered on the UKCRN portfolio. The trial is planned to start in January 2015 with publication of the trial results in 2017. Trial registration number ISRCTN 51420481. PMID:25908673

  1. Organizational development trajectory of a large academic radiotherapy department set up similarly to a prospective clinical trial: the MAASTRO experience

    PubMed Central

    Boersma, L; Dekker, A; Hermanns, E; Houben, R; Govers, M; van Merode, F; Lambin, P

    2015-01-01

    Objective: To simultaneously improve patient care processes and clinical research activities by starting a hypothesis-driven reorganization trajectory mimicking the rigorous methodology of a prospective clinical trial. Methods: The design of this reorganization trajectory was based on the model of a prospective trial. It consisted of (1) listing problems and analysing their potential causes, (2) defining interventions, (3) defining end points and (4) measuring the effect of the interventions (i.e. at baseline and after 1 and 2 years). The primary end point for patient care was the number of organizational root causes of incidents/near incidents; for clinical research, it was the number of patients in trials. There were several secondary end points. We analysed the data using two sample z-tests, χ2 test, a Mann–Whitney U test and the one-way analysis of variance with Bonferroni correction. Results: The number of organizational root causes was reduced by 27% (p < 0.001). There was no effect on the percentage of patients included in trials. Conclusion: The reorganizational trajectory was successful for the primary end point of patient care and had no effect on clinical research. Some confounding events hampered our ability to draw strong conclusions. Nevertheless, the transparency of this approach can give medical professionals more confidence in moving forward with other organizational changes in the same way. Advances in knowledge: This article is novel because managerial interventions were set up similarly to a prospective clinical trial. This study is the first of its kind in radiotherapy, and this approach can contribute to discussions about the effectiveness of managerial interventions. PMID:25679320

  2. IRMA-2 at SOLEIL: a set-up for magnetic and coherent scattering of polarized soft x-rays

    NASA Astrophysics Data System (ADS)

    Sacchi, M.; Popescu, H.; Gaudemer, R.; Jaouen, N.; Avila, A.; Delaunay, R.; Fortuna, F.; Maier, U.; Spezzani, C.

    2013-03-01

    We have designed, built and tested a new instrument for soft x-ray scattering experiments. IRMA-2 is a UHV set-up for elastic and coherent scattering experiments developed at the SEXTANTS beamline of the SOLEIL synchrotron. Applications will be in the field of solid state physics, with emphasis on the investigation of the magnetic properties of artificially structured materials.

  3. Setting up a Low-Cost Lab Management System for a Multi-Purpose Computing Laboratory Using Virtualisation Technology

    ERIC Educational Resources Information Center

    Mok, Heng Ngee; Lee, Yeow Leong; Tan, Wee Kiat

    2012-01-01

    This paper describes how a generic computer laboratory equipped with 52 workstations is set up for teaching IT-related courses and other general purpose usage. The authors have successfully constructed a lab management system based on decentralised, client-side software virtualisation technology using Linux and free software tools from VMware that…

  4. A new training set-up for trans-apical aortic valve replacement.

    PubMed

    Abdel-Sayed, Philippe; Kalejs, Martins; von Segesser, Ludwig Karl

    2009-06-01

    Trans-apical aortic valve replacement (AVR) is a new and rapidly growing therapy. However, there are only few training opportunities. The objective of our work is to build an appropriate artificial model of the heart that can replace the use of animals for surgical training in trans-apical AVR procedures. To reduce the necessity for fluoroscopy, we pursued the goal of building a translucent model of the heart that has nature-like dimensions. A simplified 3D model of a human heart with its aortic root was created in silico using the SolidWorks Computer-Aided Design (CAD) program. This heart model was printed using a rapid prototyping system developed by the Fab@Home project and dip-coated two times with dispersion silicone. The translucency of the heart model allows the perception of the deployment area of the valved-stent without using heavy imaging support. The final model was then placed in a human manikin for surgical training on trans-apical AVR procedure. Trans-apical AVR with all the necessary steps (puncture, wiring, catheterization, ballooning etc.) can be realized repeatedly in this setting.

  5. "Set Up to Fail": Institutional Racism and the Sabotage of School Improvement

    ERIC Educational Resources Information Center

    Taylor, Dianne L.; Clark, Menthia P.

    2009-01-01

    Data from two previous studies are reanalyzed using the lens of institutional racism to examine district decisions that undermined, or sabotaged, improvement efforts at schools attended by students of color. Opportunities to rectify the sabotage were available but not pursued. A model portrays the interaction between decision-maker intent,…

  6. Digital dental surface registration with laser scanner for orthodontics set-up planning

    NASA Astrophysics Data System (ADS)

    Alcaniz-Raya, Mariano L.; Albalat, Salvador E.; Grau Colomer, Vincente; Monserrat, Carlos A.

    1997-05-01

    We present an optical measuring system based on laser structured light suitable for its diary use in orthodontics clinics that fit four main requirements: (1) to avoid use of stone models, (2) to automatically discriminate geometric points belonging to teeth and gum, (3) to automatically calculate diagnostic parameters used by orthodontists, (4) to make use of low cost and easy to use technology for future commercial use. Proposed technique is based in the use of hydrocolloids mould used by orthodontists for stone model obtention. These mould of the inside of patient's mouth are composed of very fluent materials like alginate or hydrocolloids that reveal fine details of dental anatomy. Alginate mould are both very easy to obtain and very low costly. Once captured, alginate moulds are digitized by mean of a newly developed and patented 3D dental scanner. Developed scanner is based in the optical triangulation method based in the projection of a laser line on the alginate mould surface. Line deformation gives uncalibrated shape information. Relative linear movements of the mould with respect to the sensor head gives more sections thus obtaining a full 3D uncalibrated dentition model. Developed device makes use of redundant CCD in the sensor head and servocontrolled linear axis for mould movement. Last step is calibration to get a real and precise X, Y, Z image. All the process is done automatically. The scanner has been specially adapted for 3D dental anatomy capturing in order to fulfill specific requirements such as: scanning time, accuracy, security and correct acquisition of 'hidden points' in alginate mould. Measurement realized on phantoms with known geometry quite similar to dental anatomy present errors less than 0,1 mm. Scanning of global dental anatomy is 2 minutes, and generation of 3D graphics of dental cast takes approximately 30 seconds in a Pentium-based PC.

  7. How to Set up an Effective Food Tax? Comment on "Food Taxes: A New Holy Grail?".

    PubMed

    Bonnet, Céline

    2013-09-01

    Whereas public information campaigns have failed to reverse the rising trend in obesity, economists support food taxes as they suggest they can force individuals to change their eating behavior and make the agro-food industry think more about healthy food products. Excise taxes based on the unhealthy nutrient content would be more effective since they impact more on unhealthy food products than VAT (value-added-tax) taxes. Taxes based only on junk food products would avoid perverse effects on healthy nutrient. However, as eating behavior of consumers is complex, a modeling analysis would allow to assess unexpected effects on other unhealthy nutrients or products. PMID:24596873

  8. Estimating resources for setting up an HV service for postnatal depression.

    PubMed

    Fuggle, P; Haydon, K

    2000-07-01

    Postnatal depression (PND) presents a significant health burden for mothers and their offspring. Research has indicated that screening for PND increases detection (Holden et al, 1989) and also that counselling by health visitors (HVs) is an effective intervention. This article describes a pilot PND screening and treatment project which aimed to assess the resource and organizational implications of introducing new health visiting services modelled on research findings compared with existing practice. The pilot project included approximately 400 new mothers in an inner city multicultural area and confirmed previous findings regarding prevalence of PND (19%) and the effectiveness of brief counselling interventions. It resulted in significantly reduced estimates of the HV resources that would be required to introduce screening as part of the core health-visiting programme. The project also revised expected training requirements and challenged existing concerns about its appropriateness for minority cultural groups. PMID:12271224

  9. Set up an Arc Welding Code with Enthalpy Method in Upwind Scheme

    SciTech Connect

    Ho, J.-E.

    2010-05-21

    In this study, a numerical code with enthalpy method in upwind scheme is proposed to estimate the distribution of thermal stress in the molten pool, which is primarily determined by the type of the input power and travel speed of heating source. To predict the cracker deficit inside the workpiece, a simulated program satisfying the diagonal domination and Scarborough criterion provides a stable iteration. Meantime, an experimental performance, operated by robot arm 'DR-400' to provide a steady and continuous arc welding, was also conducted to verify the simulated result. By surveying the consistence of molten pool bounded by contrast shade and simulated melting contour on the surface of workpiece, the validity of model proposed to predict the thermal cracker has been successfully identified.

  10. Superconducting quantum interference devices based set-up for probing current noise and correlations in three-terminal devices

    SciTech Connect

    Pfeffer, A. H.; Kaviraj, B.; Coupiac, O.; Lefloch, F.

    2012-11-15

    We have implemented a new experimental set-up for precise measurements of current fluctuations in three-terminal devices. The system operates at very low temperatures (30 mK) and is equipped with three superconducting quantum interference devices (SQUIDs) as low noise current amplifiers. A SQUID input coil is connected to each terminal of a sample allowing the acquisition of time-dependent current everywhere in the circuit. From these traces, we can measure the current mean value, the noise, and cross-correlations between different branches of a device. In this paper, we present calibration results of noise and cross-correlations obtained using low impedance macroscopic resistors. From these results, we can extract the noise level of the set-up and show that there are no intrinsic correlations due to the measurement scheme. We also studied noise and correlations as a function of a dc current and estimated the electronic temperature of various macroscopic resistors.

  11. Monitoring of spectroscopic changes of a single trapped fission yeast cell by using a Raman tweezers set-up

    NASA Astrophysics Data System (ADS)

    Başar, G.; Kın, S.

    2008-10-01

    We demonstrate an improvement of the sensitivity of a Raman tweezers set-up, which combines optical tweezers with Raman spectroscopy. The system was tested by taking the Raman spectrum of a 4.6 μm diameter polystyrene sphere trapped in an aqueous solution. The improvement of sensitivity of the set-up was achieved by adjusting the trap depth for maximum signal to noise ratio (SNR). The maximum SNR was obtained by investigating the Raman peak of a trapped polystyrene sphere at 1001 cm -1 according to trap depth. With this system, a single trapped living Schizosaccharomyces Pombe yeast cell was sensitively monitored by taking the kinetic Raman spectra for more than 2 h. The relative intensity decrease in amide I and amide III bands, frequency increase in amide I band together with alterations in tyrosine marker band around 850 cm -1 was observed, which indicates alterations in the hydration state of protein by time progressing.

  12. Design of the Testing Set-up for a Nuclear Fuel Rod by Neutron Radiography at CARR

    NASA Astrophysics Data System (ADS)

    Wei, Guohai; Han, Songbai; Wang, Hongli; Hao, Lijie; Wu, Meimei; He, Linfeng; Wang, Yu; Liu, Yuntao; Sun, Kai; Chen, Dongfeng

    In this paper, an experimental set-up dedicated to non-destructively test a 15cm-long Pressurized Water Reactor (PWR) nuclear fuel rod by neutron radiography (NR) is described. It consists of three parts: transport container, imaging block and steel support. The design of the transport container was optimized with Monte-Carlo Simulation by the MCNP code. The material for the shell of the transport container was chosen to be lead with the thickness of 13 cm. Also, the mechanical devices were designed to control fuel rod movement inside the container. The imaging block was designed as the exposure platform, with three openings for the neutron beam, neutron converter foil, and specimen. Development and application of this experimental set-up will help gain much experience for investigating the actual irradiated fuel rod by neutron radiography at CARR in the future.

  13. Study of di-electron production in quasi-free n-p interactions at HADES set-up

    NASA Astrophysics Data System (ADS)

    Jerusalimov, A. P.; Lykasov, G. I.

    2015-11-01

    The study of e+e--pairs production in n-p interactions was carried out at HADES set-up due to irradiation of proton target by deuteron beam at Tkind = 2.5 AGeV. The momentum and angular distributions of proton-spectator an effective masses of e+e--pairs were satisfactory described by a sum of various reactions of quasi-free n-p and p-p interactions.

  14. Evaluation of RSA set-up from a clinical biplane fluoroscopy system for 3D joint kinematic analysis

    PubMed Central

    BONANZINGA, TOMMASO; SIGNORELLI, CECILIA; BONTEMPI, MARCO; RUSSO, ALESSANDRO; ZAFFAGNINI, STEFANO; MARCACCI, MAURILIO; BRAGONZONI, LAURA

    2016-01-01

    Purpose dinamic roentgen stereophotogrammetric analysis (RSA), a technique currently based only on customized radiographic equipment, has been shown to be a very accurate method for detecting three-dimensional (3D) joint motion. The aim of the present work was to evaluate the applicability of an innovative RSA set-up for in vivo knee kinematic analysis, using a biplane fluoroscopic image system. To this end, the Authors describe the set-up as well as a possible protocol for clinical knee joint evaluation. The accuracy of the kinematic measurements is assessed. Methods the Authors evaluated the accuracy of 3D kinematic analysis of the knee in a new RSA set-up, based on a commercial biplane fluoroscopy system integrated into the clinical environment. The study was organized in three main phases: an in vitro test under static conditions, an in vitro test under dynamic conditions reproducing a flexion-extension range of motion (ROM), and an in vivo analysis of the flexion-extension ROM. For each test, the following were calculated, as an indication of the tracking accuracy: mean, minimum, maximum values and standard deviation of the error of rigid body fitting. Results in terms of rigid body fitting, in vivo test errors were found to be 0.10±0.05 mm. Phantom tests in static and kinematic conditions showed precision levels, for translations and rotations, of below 0.1 mm/0.2° and below 0.5 mm/0.3° respectively for all directions. Conclusions the results of this study suggest that kinematic RSA can be successfully performed using a standard clinical biplane fluoroscopy system for the acquisition of slow movements of the lower limb. Clinical relevance a kinematic RSA set-up using a clinical biplane fluoroscopy system is potentially applicable and provides a useful method for obtaining better characterization of joint biomechanics. PMID:27602352

  15. Initial experience in setting up a medical student first responder scheme in South Central England.

    PubMed

    Seligman, William H; Ganatra, Sameer; England, David; Black, John J M

    2016-02-01

    Prehospital emergency medicine (PHEM) is a recently recognised subspecialty of emergency medicine, and anaesthetics, intensive care and acute medicine, in the UK, and yet it receives little to no mention in many undergraduate medical curricula. However, there is growing interest in PHEM among medical students and junior doctors. Several programmes are in existence across the UK that serve to provide teaching and exposure of prehospital care to medical students and junior doctors. However, relatively few students are able to gain significant first-hand experience of treating patients in the prehospital phase. In this short report, we discuss our experience of launching the student first responder (SFR) scheme across three counties in the Thames Valley. Medical students are trained by the regional ambulance service and respond to life-threatening medical emergencies in an ambulance response vehicle. The scheme is likely to benefit the ambulance service by providing a wider pool of trained volunteer first responders able to attend to emergency calls, to benefit patients by providing a quick response at their time of need, and to benefit medical students by providing first-hand experience of medical emergencies in the community. In its first 15 months of operation, SFRs were dispatched to 343 incidents. This scheme can serve as a training model for other ambulance services and medical schools across the UK.

  16. Crisis into opportunity: setting up community mental health services in post-tsunami Aceh.

    PubMed

    Jones, L M; Ghani, H A; Mohanraj, A; Morrison, S; Smith, P; Stube, D; Asare, J

    2007-01-01

    The Asian Tsunami killed more than 130,000 people and made 400,000 homeless in Aceh, an area in Indonesia already affected by over thirty years of conflict. This paper examines an approach taken by an International Non-Governmental Organisation (INGO) to address emergency mental health and psychosocial needs in an integrated way, by providing a continuum of care incorporating psychosocial support for the wider community and clinical services for the more severely affected. The model included outreach to the indigenous system. Psychosocial activities were developed in partnership with the local communities. Community-based clinical mental health services were established by identifying and building locally-based capacity at the primary health care level, and potentially sustainable services were established in collaboration with the Ministry of Health. By December 2005, four hundred and eighty three patients had been seen. More than one third suffered from serious mental disorders that predated the Tsunami. Thus, crisis provided an opportunity to address longstanding community mental health needs. The lessons learned from this approach are also discussed.

  17. Setting Up the Speech Production Network: How Oscillations Contribute to Lateralized Information Routing

    PubMed Central

    Gehrig, Johannes; Wibral, Michael; Arnold, Christiane; Kell, Christian A.

    2012-01-01

    Speech production involves widely distributed brain regions. This MEG study focuses on the spectro-temporal dynamics that contribute to the setup of this network. In 21 participants performing a cue-target reading paradigm, we analyzed local oscillations during preparation for overt and covert reading in the time-frequency domain and localized sources using beamforming. Network dynamics were studied by comparing different dynamic causal models of beta phase coupling in and between hemispheres. While a broadband low frequency effect was found for any task preparation in bilateral prefrontal cortices, preparation for overt speech production was specifically associated with left-lateralized alpha and beta suppression in temporal cortices and beta suppression in motor-related brain regions. Beta phase coupling in the entire speech production network was modulated by anticipation of overt reading. We propose that the processes underlying the setup of the speech production network connect relevant brain regions by means of beta synchronization and prepare the network for left-lateralized information routing by suppression of inhibitory alpha and beta oscillations. PMID:22685442

  18. Objectives and applications of phenotyping network set-up for livestock.

    PubMed

    Hocquette, Jean-François; Capel, Carine; David, Valérie; Guémené, Daniel; Bidanel, Joël; Ponsart, Claire; Gastinel, Pierre-Louis; Bail, Pierre-Yves Le; Monget, Philippe; Mormède, Pierre; Barbezant, Maurice; Guillou, Florian; Peyraud, Jean-Louis

    2012-07-01

    Providing phenotypic information, which is accurate, reliable, repeatable and comparable across countries or laboratories, is critical to gain a better understanding of the relationship between genes and phenotypes. So far, it is indeed extremely difficult to combine different sources of phenotypic data from multiple origins, partly because of the variability in the methods of phenotyping. The phenotyping program of livestock involves the definition of complex phenotypes obtained from data integration at different levels (from molecules to herds), the implementation of the latest technologies to accurately characterize at high speed and low cost, the greatest number of animals in a better characterized environment, and the development and sharing of large databases for data analysis and modeling. Such a program also involves the construction of a coordinated network of research and professional facilities and a common language with shared definition of unambiguous animal traits and of methods to assess them. To this end, it will build on the 'Animal Trait Ontology of Livestock' (ATOL) project with the objective of defining precisely the phenotypes of interest for farm animals. Then, it will be necessary to combine an environmental information system related to animal husbandry and associated methods to capture the phenotypic differences between animals.

  19. The Interaction Between Dynamics and Chemistry of Ozone in the Set-up Phase of the Northern Hemisphere Polar Vortex

    NASA Technical Reports Server (NTRS)

    Kawa, S. R.; Bevilacqua, R.; Margitan, J. J.; Douglass, A. R.; Schoeberl, M. R.; Hoppel, K.; Sen, B.; Bhartia, P. K. (Technical Monitor)

    2001-01-01

    The morphology and evolution of the stratospheric ozone (O3) distribution at high latitudes in the Northern Hemisphere (NH) are examined for the late summer and fall seasons of 1999. This time period sets the O3 initial condition for the SOLVE/THESEO field mission performed during winter 1999-2000. In situ and satellite data are used along with a three-dimensional model of chemistry and transport (CTM) to determine the key processes that control the distribution of O3 in the lower-to-middle stratosphere. O3 in the vortex at the beginning of the winter season is found to be nearly constant from 500 to above 800 K with a value at 3 ppmv +/- approx. 10%. Values outside the vortex are up to a factor of 2 higher and increase significantly with potential temperature. The seasonal time series of data from POAM shows that relatively low O3 mixing ratios, which characterize the vortex in late fall, are already present at high latitudes at the end of summer before the vortex circulation sets up. Analysis of the CTM output shows that the minimum O3 and increase in variance in late summer are the result of: 1) stirring of polar concentric O3 gradients by nascent wave-driven transport, and 2) an acceleration of net photochemical loss with decreasing solar illumination. The segregation of low O3 mixing ratios into the vortex as the circulation strengthens through the fall suggests a possible feedback role between O3 chemistry and the vortex formation dynamics. Trajectory calculations from O3 sample points early in the fall, however, show only a weak correlation between initial O3 mixing ratio and potential vorticity later in the season consistent with order-of-magnitude calculations for the relative importance of O3 in the fall radiative balance at high latitudes. The possible connection between O3 chemistry and the dynamics of vortex formation does suggest that these feedbacks and sensitivities need to be better understood in order to make confident predictions of the recovery

  20. Swell-generated Set-up and Infragravity Wave Propagation Over a Fringing Coral Reef: Implications for Wave-driven Inundation of Atoll Islands

    NASA Astrophysics Data System (ADS)

    Cheriton, O. M.; Storlazzi, C. D.; Rosenberger, K. J.; Quataert, E.; van Dongeren, A.

    2014-12-01

    The Republic of the Marshall Islands is comprised of 1156 islands on 29 low-lying atolls with a mean elevation of 2 m that are susceptible to sea-level rise and often subjected to overwash during large wave events. A 6-month deployment of wave and tide gauges across two shore-normal sections of north-facing coral reef on the Roi-Namur Island on Kwajalein Atoll was conducted during 2013-2014 to quantify wave dynamics and wave-driven water levels on the fringing coral reef. Wave heights and periods on the reef flat were strongly correlated to the water levels. On the fore reef, the majority of wave energy was concentrated in the incident band (5-25 s); due to breaking at the reef crest, however, the wave energy over the reef flat was dominated by infragravity-band (25-250 s) motions. Two large wave events with heights of 6-8 m at 15 s over the fore reef were observed. During these events, infragravity-band wave heights exceeded the incident band wave heights and approximately 1.0 m of set-up was established over the innermost reef flat. This set-up enabled the propagation of large waves across the reef flat, reaching maximum heights of nearly 2 m on the innermost reef flat adjacent to the toe of the beach. XBEACH models of the instrument transects were able to replicate the incident waves, infragravity waves, and wave-driven set-up across the reef when the hydrodynamic roughness of the reef was correctly parameterized. These events led to more than 3 m of wave-driven run-up and inundation of the island that drove substantial morphological change to the beach face.

  1. Comparison of prostate set-up accuracy and margins with off-line bony anatomy corrections and online implanted fiducial-based corrections.

    PubMed

    Greer, P B; Dahl, K; Ebert, M A; Wratten, C; White, M; Denham, J W

    2008-10-01

    The aim of the study was to determine prostate set-up accuracy and set-up margins with off-line bony anatomy-based imaging protocols, compared with online implanted fiducial marker-based imaging with daily corrections. Eleven patients were treated with implanted prostate fiducial markers and online set-up corrections. Pretreatment orthogonal electronic portal images were acquired to determine couch shifts and verification images were acquired during treatment to measure residual set-up error. The prostate set-up errors that would result from skin marker set-up, off-line bony anatomy-based protocols and online fiducial marker-based corrections were determined. Set-up margins were calculated for each set-up technique using the percentage of encompassed isocentres and a margin recipe. The prostate systematic set-up errors in the medial-lateral, superior-inferior and anterior-posterior directions for skin marker set-up were 2.2, 3.6 and 4.5 mm (1 standard deviation). For our bony anatomy-based off-line protocol the prostate systematic set-up errors were 1.6, 2.5 and 4.4 mm. For the online fiducial based set-up the results were 0.5, 1.4 and 1.4 mm. A prostate systematic error of 10.2 mm was uncorrected by the off-line bone protocol in one patient. Set-up margins calculated to encompass 98% of prostate set-up shifts were 11-14 mm with bone off-line set-up and 4-7 mm with online fiducial markers. Margins from the van Herk margin recipe were generally 1-2 mm smaller. Bony anatomy-based set-up protocols improve the group prostate set-up error compared with skin marks; however, large prostate systematic errors can remain undetected or systematic errors increased for individual patients. The margin required for set-up errors was found to be 10-15 mm unless implanted fiducial markers are available for treatment guidance.

  2. The effect of systematic set-up deviations on the absorbed dose distribution for left-sided breast cancer treated with respiratory gating

    NASA Astrophysics Data System (ADS)

    Edvardsson, A.; Ceberg, S.

    2013-06-01

    The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive maximum likelihood factor for the gating patients resulted in better set-up. When the uncorrected set-up deviations were simulated the average mean absorbed dose was increased from 1.38 to 2.21 Gy for the heart, 4.17 to 8.86 Gy to the left anterior descending coronary artery and 5.80 to 7.64 Gy to the left lung. Respiratory gating can induce systematic set-up deviations which would result in increased mean absorbed dose to the OARs if not corrected for and should therefore be corrected for by an appropriate correction strategy.

  3. Performance of the AGATA γ-ray spectrometer in the PreSPEC set-up at GSI

    NASA Astrophysics Data System (ADS)

    Lalović, N.; Louchart, C.; Michelagnoli, C.; Perez-Vidal, R. M.; Ralet, D.; Gerl, J.; Rudolph, D.; Arici, T.; Bazzacco, D.; Clément, E.; Gadea, A.; Kojouharov, I.; Korichi, A.; Labiche, M.; Ljungvall, J.; Lopez-Martens, A.; Nyberg, J.; Pietralla, N.; Pietri, S.; Stezowski, O.

    2016-01-01

    In contemporary nuclear physics, the European Advanced GAmma Tracking Array (AGATA) represents a crucial detection system for cutting-edge nuclear structure studies. AGATA consists of highly segmented high-purity germanium crystals and uses the pulse-shape analysis technique to determine both the position and the energy of the γ-ray interaction points in the crystals. It is the tracking algorithms that deploy this information and enable insight into the sequence of interactions, providing information on the full or partial absorption of the γ ray. A series of dedicated performance measurements for an AGATA set-up comprising 21 crystals is described. This set-up was used within the recent PreSPEC-AGATA experimental campaign at the GSI Helmholtzzentrum für Schwerionenforschung. Using the radioactive sources 56Co, 60Co and 152Eu, absolute and normalized efficiencies and the peak-to-total of the array were measured. These quantities are discussed using different data analysis procedures. The quality of the pulse-shape analysis and the tracking algorithm are evaluated. The agreement between the experimental data and the Geant4 simulations is also investigated.

  4. The influence of laboratory set-up in usability tests: effects on user performance, subjective ratings and physiological measures.

    PubMed

    Sonderegger, Andreas; Sauer, Juergen

    2009-11-01

    This article examines the influences of situational factors on user behaviour in usability tests. Sixty participants carried out two tasks on a computer-simulated prototype of a mobile phone. Employing a 3 x 2 mixed experimental design, laboratory set-up was varied as a between-subjects variable (presence of facilitator and two non-interactive observers, presence of facilitator or no person present) while task difficulty was manipulated as a within-subjects variable (low vs. high). Performance data, subjective measures and physiological parameters (e.g. heart rate variability) were taken. The results showed that the presence of non-interactive observers during a usability test led to a physiological stress response, decreased performance on some measures and affected the emotional state of test participants. The presence of a facilitator (i.e. a participating observer) also influenced the emotional state of the test participant. Practitioners involved in usability testing need to be aware of undue influences of observers, in particular, if the observers are non-interactive. The findings presented in this paper have implications for the practice of usability testing. They indicated a considerable influence of observers on test participants (physiology and emotions) and on the outcomes of usability tests (performance measures). This should be considered when selecting the set-up of a usability testing procedure.

  5. Setting up of in-vacuum PIXE system for direct elemental analysis of thick solid environmental samples.

    PubMed

    Rihawy, M S; Ismail, I M; Halloum, D

    2016-04-01

    Experimental set-up, development, characterization, and calibration of an in-vacuum PIXE system at the tandem accelerator facility of the Atomic Energy Commission of Syria (AECS) is described. The PIXE system calibration involved experimental characterization of the X-ray detector parameters and careful determination of the H-values that control dependence of the detector solid angle with the X-ray energies and correct imperfect values of the detector efficiency. Setting up of an electron flood gun to compensate charge built up and utilization of a beam profile monitor to perform indirect measurement of the beam charge, provide a direct PIXE measurement of thick insulating samples in-vacuum. The PIXE system has been subsequently examined to verify its ability to perform direct PIXE measurements on geological materials. A combination of minimum sample preparation procedures and specific experimental conditions applied enables simple and accurate elemental analysis. Elemental concentrations of several elements heavier than sodium in different reference geological samples, at about 5-10% absolute accuracy for most elements, have been determined. Comprehensive discussion of the obtained elemental concentration values, for most elements of visible X-ray peaks in the PIXE spectra, has been considered. PMID:26803668

  6. Parallel aligned liquid crystal on silicon display based optical set-up for the generation of polarization spatial distributions

    NASA Astrophysics Data System (ADS)

    Estévez, Irene; Lizana, Angel; Zheng, Xuejie; Peinado, Alba; Ramírez, Claudio; Martínez, Jose Luis; Márquez, Andrés.; Moreno, Ignacio; Campos, Juan

    2015-06-01

    Liquid Crystals on Silicon (LCOS) displays are a type of LCDs that work in reflection. Such devices, due to the double pass that the light beam performs through the LC cells, lead to larger phase modulation than transmissive LCDs with the same thickness. By taking advantage of this modulation capability exhibited by LCOS displays, we propose a new experimental set-up which is able to provide customized state of polarization spatial distributions just by means of a single LCOS display. To this aim, a double reflection on different halves of the display is properly performed. This fact is achieved by including a compact optical system that steers the light and performs a proper polarization plane rotation. The set-up has been experimentally implemented and some experimental concerns are discussed. The suitability of the system is provided by generating different experimental spatial distributions of polarization. In this regard, well-known polarization distributions, as axial, azimuthal or spiral linear polarization patterns are here provided. Based on the excellent results obtained, the suitability of the system to generate different spatially variant distributions of polarization is validated.

  7. GARFIELD + RCo digital upgrade: A modern set-up for mass and charge identification of heavy-ion reaction products

    NASA Astrophysics Data System (ADS)

    Bruno, M.; Gramegna, F.; Marchi, T.; Morelli, L.; Pasquali, G.; Casini, G.; Abbondanno, U.; Baiocco, G.; Bardelli, L.; Barlini, S.; Bini, M.; Carboni, S.; Cinausero, M.; D'Agostino, M.; Degerlier, M.; Kravchuk, V. L.; Geraci, E.; Mastinu, P. F.; Ordine, A.; Piantelli, S.; Poggi, G.; Moroni, A.

    2013-10-01

    An upgraded GARFIELD + Ring Counter (RCo) apparatus is presented with improved performances as far as electronics and detectors are concerned. On the one hand fast sampling digital read out has been extended to all detectors, allowing for an important simplification of the signal processing chain together with an enriched extracted information. On the other hand a relevant improvement has been made in the forward part of the set-up (RCo): an increased granularity of the CsI(Tl) crystals and a higher homogeneity in the silicon detector resistivity. The renewed performances of the GARFIELD + RCo array make it suitable for nuclear reaction measurements both with stable and with Radioactive Ion Beams (RIB), like the ones planned for the SPES facility, where the physics of isospin can be studied.

  8. Do you think you have what it takes to set up a long-term video monitoring unit?

    PubMed

    Smith, Sheila L

    2006-03-01

    The single most important factor when setting up a long-term video monitoring unit is research. Research all vendors by traveling to other sites and calling other facilities. Considerations with equipment include the server, acquisition units, review units, cameras, software, and monitors as well as other factors including Health Insurance Portability and Accountability Act (HIPAA) compliance. Research customer support including both field and telephone support. Involve your Clinical Engineering Department in your investigations. Be sure to obtain warranty information. Researching placement of the equipment is essential. Communication with numerous groups is vital. Administration, engineers, clinical engineering, physicians, infection control, environmental services, house supervisors, security, and all involved parties should be involved in the planning.

  9. Beam patterns in an optical parametric oscillator set-up employing walk-off compensating beta barium borate crystals

    NASA Astrophysics Data System (ADS)

    Kaucikas, M.; Warren, M.; Michailovas, A.; Antanavicius, R.; van Thor, J. J.

    2013-02-01

    This paper describes the investigation of an optical parametric oscillator (OPO) set-up based on two beta barium borate (BBO) crystals, where the interplay between the crystal orientations, cut angles and air dispersion substantially influenced the OPO performance, and especially the angular spectrum of the output beam. Theory suggests that if two BBO crystals are used in this type of design, they should be of different cuts. This paper aims to provide an experimental manifestation of this fact. Furthermore, it has been shown that air dispersion produces similar effects and should be taken into account. An x-ray crystallographic indexing of the crystals was performed as an independent test of the above conclusions.

  10. Controls on Water Storage, Mixing and Release in a Nested Catchment Set-up with Clean and Mixed Physiographic Characteristics

    NASA Astrophysics Data System (ADS)

    Pfister, L.; McDonnell, J.; Hissler, C.; Martínez-Carreras, N.; Klaus, J.

    2015-12-01

    With catchment water storage being only rarely determined, storage dynamics remain largely unknown to date. However, storage bears considerable potential for catchment inter-comparison exercises, as well as it is likely to have an important role in regulating catchment functions. Catchment comparisons across a wide range of environments and scales will help to increase our understanding of relationships between storage dynamics and catchment processes. With respect to the potential of catchment storage for bringing new momentum to catchment classification and catchment processes understanding we currently investigate spatial and temporal variability of dynamic storage in a nested catchment set-up (16 catchments) of the Alzette River basin (Luxembourg, Europe), covering a wide range of geological settings, catchment areas, contrasted landuse, and hydro-meteorological and tracer series. We define catchment storage as the total amount of water stored in a control volume, delimited by the catchment's topographical boundaries and depth of saturated and unsaturated zones. Complementary storage assessments (via input-output dynamics of natural tracers, geographical sounding, groundwater level measurements, soil moisture measurements, hydrometry) are carried out for comparison purposes. In our nested catchment set-up we have (1) assessed dependencies between geology, catchment permeability and winter runoff coefficients, (2) calculated water balance derived catchment storage and mixing potential and quantified how dynamic storage differs between catchments and scales, and (3) examined how stream baseflow dD (as a proxy for baseflow transit time) and integrated flow measures (like the flow duration curve) relate to bedrock geology. Catchments with higher bedrock permeability exhibited larger storage capacities and eventually lower average winter runoff coefficients. Over a time-span of 11 years, all catchments re-produced the same winter runoff coefficients year after year

  11. High temperature measurement set-up for the electro-mechanical characterization of robust thin film systems

    NASA Astrophysics Data System (ADS)

    Fricke, S.; Friedberger, A.; Seidel, H.; Schmid, U.

    2014-01-01

    Due to economic and environmental requirements there is a strong need both to increase the efficiency and to monitor the actual status of gas turbines, rocket engines and deep drilling systems. For these applications, micromachined pressure sensors based on a robust substrate material (e.g. sapphire) as well as strain gauges made of platinum for long-term stable operation are regarded as most promising to withstand harsh environments such as high temperature levels, aggressive media and/or high pressure loads. For pre-evaluation purposes, a novel, custom-built measurement set-up is presented allowing the determination of electro-mechanical thin film properties up to 850 °C. Key components of the measurement set-up are the one-sided clamped beam made of Al2O3 ceramics which is deflected by a quartz rod and a high precision encoder-controlled dc motor to drive the quartz rod. The specific arrangement of the infrared halogen heaters in combination with the gold coated quartz half shells ensures a high degree of temperature homogeneity along the beam axis. When exposed to tensile as well as compressive load conditions, the corresponding gauge factor values of 1 µm thick platinum thin films show a good comparison at room temperature and in the temperature range from 600 up to 850 °C where the effects originating from grain boundaries or from the film surfaces are negligible. Between 150 and 600 °C, however, a strong deviation in the gauge factor determination depending on the mechanical load condition is observed, which is attributed to the gliding of adjacent grains.

  12. Detection of actinides and rare earths in natural matrices with the AGLAE new, high sensitivity detection set-up

    NASA Astrophysics Data System (ADS)

    Zucchiatti, Alessandro; Alonso, Ursula; Lemasson, Quentin; Missana, Tiziana; Moignard, Brice; Pacheco, Claire; Pichon, Laurent; Camarena de la Mora, Sandra

    2014-08-01

    A series of granite samples (Grimsel and Äspö) enriched by sorption with natU (10-3 M, 10-4 M, 10-5 M in solution) and La (10-3 M, 10-4 M in solution) has been scanned by PIXE over a surface of 1920 × 1920 mm2 together with non-enriched Grimsel and Äspö granites and a glass standard. An assessment of minimum detection limits, MDL's, for several elements has been performed with the use of standard materials. Due to mapping and the high sensitivity of the new AGLAE detection system, U levels around 30 ppm can be detected from the whole PIXE spectrum (one low energy detector and four summed filtered detectors) while U reach grains, inhomogeneously distributed over the surface can be clearly identified through the multi elemental maps and analyzed separately. Even the nominally enriched samples have La levels below the MDL, probably because precipitation of the element (and not adsorption) mostly took place, and precipitates were eliminated after surface cleaning carried out before PIXE analyses. A multi detector system that implies a PIXE detection solid angle much wider than in any other similar set-up (a factor of 2-5); a higher events selectivity, given by the possibility of filtering individually up to 4 PIXE detectors; a double RBS detector, the new Ion Beam Induced Luminescence (IBIL) spectrometry and gamma spectrometry. Full mapping capability in air, assisted by a powerful event by event reconstruction software. These features allow lower Minimum Detection Limits (MDL) which are highly beneficial to the analysis of cultural heritage objects, meaning generally a reduction of irradiation time. Paintings will then be studied without any damage to the pigments that have color change tendencies which is a major drawback of the previous system. Alternatively they could allow an increase in information collected at equal time, particularly considering the detector's fast response and therefore the potential for high beam currents when sample damage can be

  13. A simplified edge illumination set-up for quantitative phase contrast mammography with synchrotron radiation at clinical doses

    NASA Astrophysics Data System (ADS)

    Longo, Mariaconcetta; Rigon, Luigi; Lopez, Frances C. M.; Chen, Rongchang; Dreossi, Diego; Zanconati, Fabrizio; Longo, Renata

    2015-02-01

    This work presents the first study of x-ray phase contrast imaging based on a simple implementation of the edge illumination method (EIXPCi) in the field of mammography with synchrotron radiation. A simplified EIXPCi set-up was utilized to study a possible application in mammography at clinical doses. Moreover, through a novel algorithm capable of separating and quantifying absorption and phase perturbations of images acquired in EIXPCi modality, it is possible to extract quantitative information on breast images, allowing an accurate tissue identification. The study was carried out at the SYRMEP beamline of Elettra synchrotron radiation facility (Trieste, Italy), where a mastectomy specimen was investigated with the EIXPCi technique. The sample was exposed at three different energies suitable for mammography with synchrotron radiation in order to test the validity of the novel algorithm in extracting values of linear attenuation coefficients integrated over the sample thickness. It is demonstrated that the quantitative data are in good agreement with the theoretical values of linear attenuation coefficients calculated on the hypothesis of the breast with a given composition. The results are promising and encourage the current efforts to apply the method in mammography with synchrotron radiation.

  14. TWINNING between Institutions in developed and less developed countries: an ideal way to set-up an astrophysics program

    NASA Astrophysics Data System (ADS)

    Carignan, Claude

    2015-03-01

    It is very difficult to start from scratch a new Astrophysics program in a country with very little or no researchers in the field. In 2007, we began to set-up an Astrophysics program by TWINNING the Université de Ouagadougou with the Université de Montréal in Canada, the Université de Provence in France and the University of Cape Town in South Africa. Already, courses are given at the undergraduate and Master levels and a teaching Observatory has been built. A 1m research telescope was also moved from the La Silla Observatory in Chile to Burkina Faso and the infrastructure is being built at the moment on mount Djaogari in the north-eastern part of the country. In the meantime, 6 students are doing their PhD in Astrophysics overseas (Canada, France and South Africa) and will become the core of the research group at the Université de Ouagadougou. An engineer is also doing his PhD in Astronomical Instrumentation to help with the maintenance of the equipment on the Research Telescope.

  15. An experimental set-up to study carbon, water, and nitrate uptake rates by hydroponically grown plants.

    PubMed

    Andriolo, J L; Le Bot, J; Gary, C; Sappe, G; Orlando, P; Brunel, B; Sarrouy, C

    1996-01-01

    The experimental system described allows concomitant hourly measurements of CO2, H2O, and NO3 uptake rates by plants grown hydroponically in a greenhouse. Plants are enclosed in an airtight chamber through which air flows at a controlled speed. Carbon dioxide exchange and transpiration rates are determined from respective differences of concentrations of CO2 and water vapor of the air at the system inlet and outlet. This set-up is based on the "open-system" principle with improvements made on existing systems. For instance, propeller anemometers are used to monitor air flow rates in the chamber. From their signal it is possible to continuously adjust air speed to changing environmental conditions and plant activity. The air temperature inside the system therefore never rises above that outside. Water and NO3 uptake rates are calculated at time intervals from changes in the volume and the NO3 concentration of the nutrient solution in contact with the roots. The precise measurement of the volume of solution is achieved using a balance which has a higher precision than any liquid level sensors. Nitrate concentration is determined in the laboratory from aliquots of solution sampled at time intervals. A number of test runs are reported which validate the measurements and confirm undisturbed conditions within the system. Results of typical diurnal changes in CO2, H2O, and NO3 uptake rates by fruiting tomato plants are also presented.

  16. The upgraded external-beam PIXE/PIGE set-up at LABEC for very fast measurements on aerosol samples

    NASA Astrophysics Data System (ADS)

    Lucarelli, F.; Calzolai, G.; Chiari, M.; Giannoni, M.; Mochi, D.; Nava, S.; Carraresi, L.

    2014-01-01

    At the 3 MV Tandetron accelerator of the LABEC laboratory of INFN in Florence, an external beam facility is fully dedicated to measurements of elemental composition of atmospheric aerosol. The experimental set-up hitherto used for this kind of applications has been upgraded with the replacement of a traditional Si(Li) detector for the detection of medium-high Z elements with a silicon drift detector (SDD) with a big active area (80 mm2) and 450 μm thickness, with the aim of obtaining better minimum detection limits (MDL) and reduce measuring times. The Upilex extraction window has been replaced by a more resistant one (Si3N4). A comparison between the old Si(Li) and the new SDD for aerosol samples collected on different substrata like Teflon, Kapton and Nuclepore evidenced the better performances of the SDD. It allows obtaining better results (higher counting statistics, lower MDLs) even in shorter measuring times, thus allowing very fast analysis of both daily and hourly samples.

  17. Linking mathematics with engineering applications at an early stage - implementation, experimental set-up and evaluation of a pilot project

    NASA Astrophysics Data System (ADS)

    Rooch, Aeneas; Junker, Philipp; Härterich, Jörg; Hackl, Klaus

    2016-03-01

    Too difficult, too abstract, too theoretical - many first-year engineering students complain about their mathematics courses. The project MathePraxis aims to resolve this disaffection. It links mathematical methods as they are taught in the first semesters with practical problems from engineering applications - and thereby shall give first-year engineering students a vivid and convincing impression of where they will need mathematics in their later working life. But since real applications usually require more than basic mathematics and first-year engineering students typically are not experienced with construction, mensuration and the use of engineering software, such an approach is hard to realise. In this article, we show that it is possible. We report on the implementation of MathePraxis at Ruhr-Universität Bochum. We describe the set-up and the implementation of a course on designing a mass damper which combines basic mathematical techniques with an impressive experiment. In an accompanying evaluation, we have examined the students' motivation relating to mathematics. This opens up new perspectives how to address the need for a more practically oriented mathematical education in engineering sciences.

  18. Set-up of debris-flow monitoring stations in the Eastern Pyrenees. Preliminary results and first experiences.

    NASA Astrophysics Data System (ADS)

    Hürlimann, Marcel; Abancó, Claudia; Moya, Jose; Chevalier, Guillaume; Raïmat, Carles; Luis-Fonseca, Roberto

    2010-05-01

    Direct observations of debris flows in the field by monitoring stations are of great importance to improve understandings of triggering, flow behaviour and accumulation of debris flows. Upon the knowledge of the authors, in Europe debris-flow monitoring stations are only situated in the Alps (Italy and Switzerland), while no test site is located in a catchment affected by Mediterranean climate. In 2005, the first monitoring system was set up by GEOBRUGG IBERICA SA in the Erill catchment, situated in the Axial Pyrenees. A flexible ring net VX160-H4 with load-cells was installed together with a video camera and four geophones. In addition, a meteorological station completed the instrumentation. During 2009, the monitoring of two additional catchments has been set up; Senet in the Axial Pyrenees and Ensija in the Pre-Pyrenees. Four geophones and one ultrasonic device are installed along the torrent in order to determine the flow velocity and flow depth/discharge of the events. As in Erill, a meteorological station completes the devices and measures rainfall and temperature. The main objective of the three monitoring stations is to get some insights on how the Mediterranean climate influences the critical rainfall for debris-flow initiation. The flow behaviour of debris flows is another major goal, while the Erill test site focuses basically on the effectiveness of flexible ring nets. In addition, the Erill installation also acts as protection for the village located on the fan. The calibration, installation and analysis during the testing phase showed that a correct implementation of the different sensors is not an easy task and needs knowledge in geophysics, electronics, telecommunications etc. Especially geophones and ultrasonic devices need special attentions. Geophone outputs are strongly affected by the type of underground and the distance to the torrent, while the measures of the ultrasonic sensor clearly depend on the temperature. To simplify the data storage

  19. Contrast-Enhanced Proton Radiography for Patient Set-up by Using X-Ray CT Prior Knowledge

    SciTech Connect

    Spadea, Maria Francesca; Fassi, Aurora; Zaffino, Paolo; Riboldi, Marco; Baroni, Guido; Depauw, Nicolas; Seco, Joao

    2014-11-01

    Purpose: To obtain a contrasted image of the tumor region during the setup for proton therapy in lung patients, by using proton radiography and x-ray computed tomography (CT) prior knowledge. Methods and Materials: Six lung cancer patients' CT scans were preprocessed by masking out the gross tumor volume (GTV), and digitally reconstructed radiographs along the planned beam's eye view (BEV) were generated, for a total of 27 projections. Proton radiographies (PR) were also computed for the same BEV through Monte Carlo simulations. The digitally reconstructed radiograph was subtracted from the corresponding proton image, resulting in a contrast-enhanced proton radiography (CEPR). Michelson contrast analysis was performed both on PR and CEPR. The tumor region was then automatically segmented on CEPR and compared to the ground truth (GT) provided by physicians in terms of Dice coefficient, accuracy, precision, sensitivity, and specificity. Results: Contrast on CEPR was, on average, 4 times better than on PR. For 10 lateral projections (±45° off of 90° or 270°), although it was not possible to distinguish the tumor region in the PR, CEPR offers excellent GTV visibility. The median ± quartile values of Dice, precision, and accuracy indexes were 0.86 ± 0.03, 0.86 ± 0.06, and 0.88 ± 0.02, respectively, thus confirming the reliability of the method in highlighting tumor boundaries. Sensitivity and specificity analysis demonstrated that there is no systematic over- or underestimation of the tumor region. Identification of the tumor boundaries using CEPR resulted in a more accurate and precise definition of GTV compared to that obtained from pretreatment CT. Conclusions: In most proton centers, the current clinical protocol is to align the patient using kV imaging with bony anatomy as a reference. We demonstrated that CEPR can significantly improve tumor visualization, allowing better patient set-up and permitting image guided proton therapy (IGPT)

  20. Decompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set up.

    PubMed

    Papadopoulou, Virginie; Evgenidis, Sotiris; Eckersley, Robert J; Mesimeris, Thodoris; Balestra, Costantino; Kostoglou, Margaritis; Tang, Meng-Xing; Karapantsios, Thodoris D

    2015-05-01

    Vascular gas bubbles are routinely observed after scuba dives using ultrasound imaging, however the precise formation mechanism and site of these bubbles are still debated and growth from decompression in vivo has not been extensively studied, due in part to imaging difficulties. An experimental set-up was developed for optical recording of bubble growth and density on tissue surface area during hyperbaric decompression. Muscle and fat tissues (rabbits, ex vivo) were covered with nitrogen saturated distilled water and decompression experiments performed, from 3 to 0bar, at a rate of 1bar/min. Pictures were automatically acquired every 5s from the start of the decompression for 1h with a resolution of 1.75μm. A custom MatLab analysis code implementing a circular Hough transform was written and shown to be able to track bubble growth sequences including bubble center, radius, contact line and contact angles over time. Bubble density, nucleation threshold and detachment size, as well as coalescence behavior, were shown significantly different for muscle and fat tissues surfaces, whereas growth rates after a critical size were governed by diffusion as expected. Heterogeneous nucleation was observed from preferential sites on the tissue substrate, where the bubbles grow, detach and new bubbles form in turn. No new nucleation sites were observed after the first 10min post decompression start so bubble density did not vary after this point in the experiment. In addition, a competition for dissolved gas between adjacent multiple bubbles was demonstrated in increased delay times as well as slower growth rates for non-isolated bubbles. PMID:25835147

  1. Decompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set up.

    PubMed

    Papadopoulou, Virginie; Evgenidis, Sotiris; Eckersley, Robert J; Mesimeris, Thodoris; Balestra, Costantino; Kostoglou, Margaritis; Tang, Meng-Xing; Karapantsios, Thodoris D

    2015-05-01

    Vascular gas bubbles are routinely observed after scuba dives using ultrasound imaging, however the precise formation mechanism and site of these bubbles are still debated and growth from decompression in vivo has not been extensively studied, due in part to imaging difficulties. An experimental set-up was developed for optical recording of bubble growth and density on tissue surface area during hyperbaric decompression. Muscle and fat tissues (rabbits, ex vivo) were covered with nitrogen saturated distilled water and decompression experiments performed, from 3 to 0bar, at a rate of 1bar/min. Pictures were automatically acquired every 5s from the start of the decompression for 1h with a resolution of 1.75μm. A custom MatLab analysis code implementing a circular Hough transform was written and shown to be able to track bubble growth sequences including bubble center, radius, contact line and contact angles over time. Bubble density, nucleation threshold and detachment size, as well as coalescence behavior, were shown significantly different for muscle and fat tissues surfaces, whereas growth rates after a critical size were governed by diffusion as expected. Heterogeneous nucleation was observed from preferential sites on the tissue substrate, where the bubbles grow, detach and new bubbles form in turn. No new nucleation sites were observed after the first 10min post decompression start so bubble density did not vary after this point in the experiment. In addition, a competition for dissolved gas between adjacent multiple bubbles was demonstrated in increased delay times as well as slower growth rates for non-isolated bubbles.

  2. A new particle-induced X-ray emission set-up for laterally resolved analysis over wide areas

    NASA Astrophysics Data System (ADS)

    Hanf, D.; Buchriegler, J.; Renno, A. D.; Merchel, S.; Munnik, F.; Ziegenrücker, R.; Scharf, O.; Nowak, S. H.; von Borany, J.

    2016-06-01

    The recently installed and unique PIXE (particle-induced X-ray emission) set-up at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) is mainly dedicated to applications for a detailed overview of elemental composition over large sample areas within a short time even at trace level. The so-called High-Speed-PIXE (HS-PIXE), a combination of a pnCCD-based pixel-detector with polycapillary X-ray optics, offers simultaneous imaging of sample areas up to 12 × 12 mm2 with a lateral resolution better than 100 μm. Each of the 264 × 264 individual pixels detects X-ray photons in an energy range from 2 keV to 20 keV with an energy resolution of 152 eV (@Mn-Kα). A high precision sample manipulator offers the inspection of areas up to 250 × 250 mm2. During first experiments the determined resolution is (76 ± 23) μm using a sample of well-known sharp-edged chromium patterns. Trace element analysis has been performed using a geological sample, a tin ore, with an average Ta-concentration below 0.1 at.%. Fine-zoned structures became visible in the Ta-Lα intensity map within only 45 min. The High-Speed-PIXE closes a gap in the analytical process flow chain especially for geoanalytical characterisations. It is a unique and fast detection system to identify areas of interest in comparably short time at large-area scale for further analysis.

  3. Assessment and quantification of patient set-up errors in nasopharyngeal cancer patients and their biological and dosimetric impact in terms of generalized equivalent uniform dose (gEUD), tumour control probability (TCP) and normal tissue complication probability (NTCP)

    PubMed Central

    Marcie, S; Fellah, M; Chami, S; Mekki, F

    2015-01-01

    Objective: The aim of this study is to assess and quantify patients' set-up errors using an electronic portal imaging device and to evaluate their dosimetric and biological impact in terms of generalized equivalent uniform dose (gEUD) on predictive models, such as the tumour control probability (TCP) and the normal tissue complication probability (NTCP). Methods: 20 patients treated for nasopharyngeal cancer were enrolled in the radiotherapy–oncology department of HCA. Systematic and random errors were quantified. The dosimetric and biological impact of these set-up errors on the target volume and the organ at risk (OARs) coverage were assessed using calculation of dose–volume histogram, gEUD, TCP and NTCP. For this purpose, an in-house software was developed and used. Results: The standard deviations (1SDs) of the systematic set-up and random set-up errors were calculated for the lateral and subclavicular fields and gave the following results: ∑ = 0.63 ± (0.42) mm and σ = 3.75 ± (0.79) mm, respectively. Thus a planning organ at risk volume (PRV) margin of 3 mm was defined around the OARs, and a 5-mm margin used around the clinical target volume. The gEUD, TCP and NTCP calculations obtained with and without set-up errors have shown increased values for tumour, where ΔgEUD (tumour) = 1.94% Gy (p = 0.00721) and ΔTCP = 2.03%. The toxicity of OARs was quantified using gEUD and NTCP. The values of ΔgEUD (OARs) vary from 0.78% to 5.95% in the case of the brainstem and the optic chiasm, respectively. The corresponding ΔNTCP varies from 0.15% to 0.53%, respectively. Conclusion: The quantification of set-up errors has a dosimetric and biological impact on the tumour and on the OARs. The developed in-house software using the concept of gEUD, TCP and NTCP biological models has been successfully used in this study. It can be used also to optimize the treatment plan established for our patients. Advances in knowledge: The g

  4. Fluorescence multi-scale endoscopy and its applications in the study and diagnosis of gastro-intestinal diseases: set-up design and software implementation

    NASA Astrophysics Data System (ADS)

    Gómez-García, Pablo Aurelio; Arranz, Alicia; Fresno, Manuel; Desco, Manuel; Mahmood, Umar; Vaquero, Juan José; Ripoll, Jorge

    2015-06-01

    Endoscopy is frequently used in the diagnosis of several gastro-intestinal pathologies as Crohn disease, ulcerative colitis or colorectal cancer. It has great potential as a non-invasive screening technique capable of detecting suspicious alterations in the intestinal mucosa, such as inflammatory processes. However, these early lesions usually cannot be detected with conventional endoscopes, due to lack of cellular detail and the absence of specific markers. Due to this lack of specificity, the development of new endoscopy technologies, which are able to show microscopic changes in the mucosa structure, are necessary. We here present a confocal endomicroscope, which in combination with a wide field fluorescence endoscope offers fast and specific macroscopic information through the use of activatable probes and a detailed analysis at cellular level of the possible altered tissue areas. This multi-modal and multi-scale imaging module, compatible with commercial endoscopes, combines near-infrared fluorescence (NIRF) measurements (enabling specific imaging of markers of disease and prognosis) and confocal endomicroscopy making use of a fiber bundle, providing a cellular level resolution. The system will be used in animal models exhibiting gastro-intestinal diseases in order to analyze the use of potential diagnostic markers in colorectal cancer. In this work, we present in detail the set-up design and the software implementation in order to obtain simultaneous RGB/NIRF measurements and short confocal scanning times.

  5. In Search of the Economic Sustainability of Hadron Therapy: The Real Cost of Setting Up and Operating a Hadron Facility

    SciTech Connect

    Vanderstraeten, Barbara; Verstraete, Jan; De Croock, Roger; De Neve, Wilfried; Lievens, Yolande

    2014-05-01

    Purpose: To determine the treatment cost and required reimbursement for a new hadron therapy facility, considering different technical solutions and financing methods. Methods and Materials: The 3 technical solutions analyzed are a carbon only (COC), proton only (POC), and combined (CC) center, each operating 2 treatment rooms and assumed to function at full capacity. A business model defines the required reimbursement and analyzes the financial implications of setting up a facility over time; activity-based costing (ABC) calculates the treatment costs per type of patient for a center in a steady state of operation. Both models compare a private, full-cost approach with public sponsoring, only taking into account operational costs. Results: Yearly operational costs range between €10.0M (M = million) for a publicly sponsored POC to €24.8M for a CC with private financing. Disregarding inflation, the average treatment cost calculated with ABC (COC: €29,450; POC: €46,342; CC: €46,443 for private financing; respectively €16,059, €28,296, and €23,956 for public sponsoring) is slightly lower than the required reimbursement based on the business model (between €51,200 in a privately funded POC and €18,400 in COC with public sponsoring). Reimbursement for privately financed centers is very sensitive to a delay in commissioning and to the interest rate. Higher throughput and hypofractionation have a positive impact on the treatment costs. Conclusions: Both calculation methods are valid and complementary. The financially most attractive option of a publicly sponsored COC should be balanced to the clinical necessities and the sociopolitical context.

  6. "helix Nebula - the Science Cloud", a European Science Driven Cross-Domain Initiative Implemented in via AN Active Ppp Set-Up

    NASA Astrophysics Data System (ADS)

    Lengert, W.; Mondon, E.; Bégin, M. E.; Ferrer, M.; Vallois, F.; DelaMar, J.

    2015-12-01

    Helix Nebula, a European science cross-domain initiative building on an active PPP, is aiming to implement the concept of an open science commons[1] while using a cloud hybrid model[2] as the proposed implementation solution. This approach allows leveraging and merging of complementary data intensive Earth Science disciplines (e.g. instrumentation[3] and modeling), without introducing significant changes in the contributors' operational set-up. Considering the seamless integration with life-science (e.g. EMBL), scientific exploitation of meteorological, climate, and Earth Observation data and models open an enormous potential for new big data science. The work of Helix Nebula has shown that is it feasible to interoperate publicly funded infrastructures, such as EGI [5] and GEANT [6], with commercial cloud services. Such hybrid systems are in the interest of the existing users of publicly funded infrastructures and funding agencies because they will provide "freedom and choice" over the type of computing resources to be consumed and the manner in which they can be obtained. But to offer such freedom and choice across a spectrum of suppliers, various issues such as intellectual property, legal responsibility, service quality agreements and related issues need to be addressed. Finding solutions to these issues is one of the goals of the Helix Nebula initiative. [1] http://www.egi.eu/news-and-media/publications/OpenScienceCommons_v3.pdf [2] http://www.helix-nebula.eu/events/towards-the-european-open-science-cloud [3] e.g. https://sentinel.esa.int/web/sentinel/sentinel-data-access [5] http://www.egi.eu/ [6] http://www.geant.net/

  7. The set-up for forward scattered particle detection at the external microbeam facility of the INFN-LABEC laboratory in Florence

    NASA Astrophysics Data System (ADS)

    Giuntini, L.; Massi, M.; Calusi, S.; Gelli, N.; Castelli, L.; Carraresi, L.; Czelusniak, C.; Fedi, M. E.; Gueli, A. M.; Liccioli, L.; Mandò, P. A.; Mazzinghi, A.; Palla, L.; Ruberto, C.; Taccetti, F.

    2015-04-01

    In the last few years some new implementations and upgrades have been made to the external scanning microbeam of INFN-LABEC laboratory in Florence, enriching the existing PIXE, PIGE, BS, IBIL set-up with complementary techniques, when possible allowing for simultaneous multi-technique analyses. We developed a system, compatible with the existing set-up, for the out-of-vacuum detection of the forward scattered particles. This system makes feasible the external-STIM (Scanning Transmission Ion Microscopy) and external-FS (Forward Scattering), now both available at our beamline. Test measurements are shortly presented.

  8. Sensitivity study of the UHI in the city of Szeged (Hungary) to different offline simulation set-ups using SURFEX/TEB

    NASA Astrophysics Data System (ADS)

    Zsebeházi, Gabriella; Hamdi, Rafiq; Szépszó, Gabriella

    2015-04-01

    Urbanised areas modify the local climate due to the physical properties of surface subjects and their morphology. The urban effect on local climate and regional climate change interact, resulting in more serious climate change impacts (e.g., more heatwave events) over cities. Majority of people are now living in cities and thus, affected by these enhanced changes. Therefore, targeted adaptation and mitigation strategies in cities are of high importance. Regional climate models (RCMs) are sufficient tools for estimating future climate change of an area in detail, although most of them cannot represent the urban climate characteristics, because their spatial resolution is too coarse (in general 10-50 km) and they do not use a specific urban parametrization over urbanized areas. To describe the interactions between the urban surface and atmosphere on few km spatial scale, we use the externalised SURFEX land surface scheme including the TEB urban canopy model in offline mode (i.e. the interaction is only one-way). The driving atmospheric conditions highly influence the impact results, thus the good quality of these data is particularly essential. The overall aim of our research is to understand the behaviour of the impact model and its interaction with the forcing coming from the atmospheric model in order to reduce the biases, which can lead to qualified impact studies of climate change over urban areas. As a preliminary test, several short (few-day) 1 km resolution simulations are carried out over a domain covering a Hungarian town, Szeged, which is located at the flat southern part of Hungary. The atmospheric forcing is provided by ALARO (a new version of the limited-area model of the ARPEGE-IFS system running at the Royal Meteorological Institute of Belgium) applied over Hungary. The focal point of our investigations is the ability of SURFEX to simulate the diurnal evolution and spatial pattern of urban heat island (UHI). Different offline simulation set-ups have

  9. 7 CFR Exhibit J to Subpart A of... - Manufactured Home Sites, Rental Projects and Subdivisions: Development, Installation and Set-Up

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... BEST OF THE MANUFACTURER'S KNOWLEDGE AND BELIEF THAT THIS MANUFACTURED HOME HAS BEEN INSPECTED IN... established frost line without exceeding the safe bearing capacity of the supporting soil. Set-Up. The work...: 1. Federal Manufactured Home Construction and Safety Standards, 24 CFR part 3280, mandated...

  10. The Setting-up of Multi-Site School Collaboratives: The Benefits of This Organizational Reform in Terms of Networking Opportunities and Their Effects

    ERIC Educational Resources Information Center

    Mifsud, Denise

    2015-01-01

    This article, which is set within the Maltese education scenario of unfolding decentralization through the setting-up of multi-site school collaboratives (legally termed "colleges") via a policy mandate, explores a particular aspect of this reform--that of "networking". This is examined in terms of the potential for…

  11. Construction of Synthetic Populations with Key Attributes: Simulation Set-up while Accommodating Multiple Approaches within a Flexible Simulation Platform

    SciTech Connect

    Fernandez, Steven J; Rose, Amy N; Bright, Eddie A; Beaver, Justin M; Symons, Christopher T; Omitaomu, Olufemi A

    2010-01-01

    In this paper, we describe our concept for overcoming the data barriers of building credible synthetic populations to assist the transformation between social theories and mathematical models. We specifically developed a 31-million-agent model of Afghanistan s population to demonstrate the ability to computationally control and analytically manipulate a system with the large number of agents (i.e., 108) necessary to model regions at the individual level using the LandScan Global population database. Afghanistan was selected for this case study because gathering data for Afghanistan was thought to be especially challenging. The LandScan Global population database is used by a majority of key U.S. and foreign agencies as their database system for worldwide geospatial distribution of populations. Assigning attributes to disaggregated population was achieved by fusing appropriate indicator databases using two forms of aggregation techniques geographical and categorical. A new approach of matching attributes to theoretical constructs was illustrated. The other data sources used include data on military and peacekeeper forces loyalties, readiness, and deployment collected through a combination of UN and classified force projections; economic data collected at the national level and disaggregated using data fusion techniques; data on social attitudes, beliefs, and social cleavages through anthropological studies, worldwide polling, and classified sources; and data on infrastructure and information systems and networks.

  12. Developing a virtual reality application for training nuclear power plant operators: setting up a database containing dose rates in the refuelling plant.

    PubMed

    Ródenas, J; Zarza, I; Burgos, M C; Felipe, A; Sánchez-Mayoral, M L

    2004-01-01

    Operators in Nuclear Power Plants can receive high doses during refuelling operations. A training programme for simulating refuelling operations will be useful in reducing the doses received by workers as well as minimising operation time. With this goal in mind, a virtual reality application is developed within the framework of the CIPRES project. The application requires doses, both instantaneous and accumulated, to be displayed at all times during operator training. Therefore, it is necessary to set up a database containing dose rates at every point in the refuelling plant. This database is based on radiological protection surveillance data measured in the plant during refuelling operations. Some interpolation routines have been used to estimate doses through the refuelling plant. Different assumptions have been adopted in order to perform the interpolation and obtain consistent data. In this paper, the procedures developed to set up the dose database for the virtual reality application are presented and analysed.

  13. Development of a new in-air micro-PIXE set-up with in-vacuum charge measurements in Atomki

    NASA Astrophysics Data System (ADS)

    Török, Zs.; Huszánk, R.; Csedreki, L.; Dani, J.; Szoboszlai, Z.; Kertész, Zs.

    2015-11-01

    A new external microbeam set-up has recently been installed as the extension of the existing microprobe system at the Laboratory of Ion Beam Applications of Atomki, Debrecen, Hungary. The external beam set-up, based on the system of Oxford Microbeams (OM), is equipped with two X-ray detectors for PIXE analysis, a digital microscope, two alignment lasers and a precision XYZ stage for easy and reproducible positioning of the sample. Exit windows with different thicknesses and of different materials can be used according to the actual demands, currently silicon-nitride (Si3N4) film with 200 nm thickness is employed in our laboratory. The first application was demonstrated in the field of archaeometry, on Bronze Age hoards from Hungary.

  14. Setting up a Prospective Thyroid Biobank for Translational Research: Practical Approach of a Single Institution (2004-2009, Pasteur Hospital, Nice, France).

    PubMed

    Lassalle, Sandra; Hofman, Véronique; Ilie, Marius; Butori, Catherine; Bonnetaud, Christelle; Gaziello, Marie Clotilde; Selva, Eric; Gavric-Tanga, Virginie; Guevara, Nicolas; Castillo, Laurent; Santini, José; Chabannon, Christian; Hofman, Paul

    2011-03-01

    In the last few years, conditions for setting up a human biobank in France have been upgraded by taking into account (1) the new laws and regulations that integrate the ethical and societal dimension of biobanking and delineate the risks for patients associated with the procurement of human cells and tissues, (2) the increasing request by scientists for human samples with proven biological quality and sophisticated sets of annotations, including information produced through the evergrowing use of molecular biology in pathology, and (3) establishment of procedures concerning the safety of the personnel working with biological products. For this purpose, health authorities and national research institutes in France have provided significant support for the set up of biobanks. The present work was conducted to describe how we set up a biobank targeting diseases of a specific organ (thyroid gland), with the aim of rapidly developing translational research projects. The prospective experience of a single institution (Pasteur Hospital, Nice, France) over a 6-year period (2004-2009) is presented from the practical point of view of a surgical pathology laboratory. We describe different procedures required to obtain high-quality thyroid biological resources and clinical annotations. The procedures were established for the management of biological products obtained from 1454 patients who underwent thyroid surgery. The preanalytical steps leading to the storage of frozen specimens were carried out in parallel with diagnostic procedures. As the number of international networks for research programs using biological products is steadily increasing, it is crucial to harmonize the procedures used by biobanks. In this regard, the described thyroid biobank has been set up using criteria established by the French National Cancer Institute (Institut National du Cancer) to guarantee the quality of different collections stored in biobanks. PMID:24850201

  15. Draft Genome Sequence of Bacillus simplex DSM 1321 for Setting Up Phylogenomics in Genomic Taxonomy of the Bacillus-Like Bacteria

    PubMed Central

    Liu, Guo-hong; Wang, Jie-ping; Che, Jian-mei; Chen, Qian-qian; Chen, Zheng

    2016-01-01

    Bacillus simplex DSM 1321 is a Gram-positive, spore-forming, and aerobic bacterium. Here, we report the draft genome sequence of B. simplex DSM 1321, with 6,494,937 bp, which will provide useful information for setting up phylogenomics in genomic taxonomy of the Bacillus-like bacteria as well as for the functional gene mining and application of B. simplex DSM 1321. PMID:27340061

  16. SU-E-CAMPUS-T-01: Analysis of the Precision of Patient Set-Up, and Fidelity of the Delivered Dose Distribution in Proton Therapy of Ocular Tumors

    SciTech Connect

    Trofimov, A; Carpenter, K; Shih, HA

    2014-06-15

    Purpose: To quantify daily set-up variations in fractionated proton therapy of ocular melanomas, and to assess the effect on the fidelity of delivered distribution to the plan. Methods: In a typical five-fraction course, daily set-up is achieved by matching the position of fiducial markers in orthogonal radiographs to the images generated by treatment planning program. A patient maintains the required gaze direction voluntarily, without the aid of fixation devices. Confirmation radiographs are acquired to assess intrafractional changes. For this study, daily radiographs were analyzed to determine the daily iso-center position and apparent gaze direction, which were then transferred to the planning system to calculate the dose delivered in individual fractions, and accumulated dose for the entire course. Dose-volume metrics were compared between the planned and accumulated distributions for the tumor and organs at risk, for representative cases that varied by location within the ocular globe. Results: The analysis of the first set of cases (3 posterior, 3 transequatorial and 4 anterior tumors) revealed varying dose deviation patterns, depending on the tumor location. For anterior and posterior tumors, the largest dose increases were observed in the lens and ciliary body, while for the equatorial tumors, macula, optic nerve and disk, were most often affected. The iso-center position error was below 1.3 mm (95%-confidence interval), and the standard deviation of daily polar and azimuthal gaze set-up were 1.5 and 3 degrees, respectively. Conclusion: We quantified interfractional and intrafractional set-up variation, and estimated their effect on the delivered dose for representative cases. Current safety margins are sufficient to maintain the target coverage, however, the dose delivered to critical structures often deviates from the plan. The ongoing analysis will further explore the patterns of dose deviation, and may help to identify particular treatment scenarios

  17. The Interaction Between Dynamics and Chemistry of Ozone in the Set-Up Phase of the Northern Hemisphere Polar Vortex

    NASA Technical Reports Server (NTRS)

    Kawa, S.R.; Douglass, A. R.; Bevilacqua, R.; Margitan, J. J.; Sen, B.; Einaudi, Franco (Technical Monitor)

    2000-01-01

    Understanding stratospheric ozone loss to the point of accurately predicting ozone in the future requires correctly distinguishing chemical from transport-induced changes in ozone. For example, evaluating the impact of chlorine reduction in controlling stratospheric ozone loss requires estimating the amount of ozone lost in chemical reactions in the polar winter and spring. The Northern Hemisphere winter polar region is a particularly crucial and interesting area because it appears that the Northern vortex may currently be poised near the threshold of extreme ozone destruction such as that which now occurs annually in the Antarctic ozone "hole." In this presentation we explore the interaction of ozone transport and chemistry through the Northern late summer and fall seasons as the vortex circulation becomes established. This phase of the seasonal cycle determines the starting point for heterogeneous processes and chlorine-driven loss that take control in the winter vortex. Using a combination of profile data from POAM, HALOE, and in situ measurements, we show that relatively low ozone at high latitudes in the middle stratosphere is associated with vortex airmasses and that these ozone abundances evolve photochemically from characteristically higher values at the end of the summer. The zonal variance of ozone mixing ratio also increases greatly at this time consistent with increasing wave-driven transport. Comparison with a three-dimensional chemistry-transport model is used to generalize the findings from the limited set of observations and quantify the relative roles of transport and chemistry in determining the ozone mixing ratio distributions.

  18. Setting Up an Efficient Therapeutic Hypothermia Team in Conscious ST Elevation Myocardial Infarction Patients: A UK Heart Attack Center Experience

    PubMed Central

    Islam, Shahed; Hampton-Till, James; MohdNazri, Shah; Watson, Noel; Gudde, Ellie; Gudde, Tom; Kelly, Paul A.; Tang, Kare H.

    2015-01-01

    Patients presenting with ST elevation myocardial infarction (STEMI) are routinely treated with percutaneous coronary intervention to restore blood flow in the occluded artery to reduce infarct size (IS). However, there is evidence to suggest that the restoration of blood flow can cause further damage to the myocardium through reperfusion injury (RI). Recent research in this area has focused on minimizing damage to the myocardium caused by RI. Therapeutic hypothermia (TH) has been shown to be beneficial in animal models of coronary artery occlusion in reducing IS caused by RI if instituted early in an ischemic myocardium. Data in humans are less convincing to date, although exploratory analyses suggest that there is significant clinical benefit in reducing IS if TH can be administered at the earliest recognition of ischemia in anterior myocardial infarction. The Essex Cardiothoracic Centre is the first UK center to have participated in administering TH in conscious patients presenting with STEMI as part of the COOL-AMI case series study. In this article, we outline our experience of efficiently integrating conscious TH into our primary percutaneous intervention program to achieve 18 minutes of cooling duration before reperfusion, with no significant increase in door-to-balloon times, in the setting of the clinical trial. PMID:26154447

  19. Setting up an off-site emergency mortuary facility (EMF) to deal with a DVI incident: disaster victim management (DVM).

    PubMed

    Eitzen, David; Zimmermann, Alex

    2012-06-01

    Forensic mortuaries in all Australian jurisdictions are dealing with increasing workloads, with routine cases regularly occupying greater than 50%, and often as much as 85%, of existing cold room body storage capacity, particularly over long weekends and during seasonal increases in respiratory infections. Hence the need to deal with a sudden influx of deceased persons or multiple body parts in a mass fatality incident would overwhelm most Australian forensic mortuaries, thereby requiring other means of body storage and processing. Exercise "Construct" was a joint South Australian Police (SAPol) and Forensic Science South Australia exercise designed to practice the establishment and construction of an emergency mortuary facility (EMF) to deal with a mass fatality incident and the subsequent disaster victim identification process. The aims of the exercise were to test preparedness, activation and construction processes relative to the establishment of an EMF. The exercise provided the opportunity to identify gaps in the capacity to successfully complete the tasks within the allotted time frames. The exercise reinforced the need to have a comprehensive and clearly documented process which must include a current list of suppliers who can deliver goods and services in a timely manner. The aim of this paper is to report on the exercise findings and share the experience with other jurisdictions. It will also provide other jurisdictions with the opportunity to consider whether the South Australian model will be useful to them in improving their own response when confronted with a mass fatality incident that may overwhelm existing local mortuary capacities and capabilities.

  20. Use of natural clays as sorbent materials for rare earth ions: Materials characterization and set up of the operative parameters.

    PubMed

    Iannicelli-Zubiani, Elena Maria; Cristiani, Cinzia; Dotelli, Giovanni; Gallo Stampino, Paola; Pelosato, Renato; Mesto, Ernesto; Schingaro, Emanuela; Lacalamita, Maria

    2015-12-01

    Two mineral clays of the montmorillonite group were tested as sorbents for the removal of Rare Earths (REs) from liquid solutions. Lanthanum and neodymium model solutions were used to perform uptake tests in order to: (a) verify the clays sorption capability, (b) investigate the sorption mechanisms and (c) optimize the experimental parameters, such as contact time and pH. The desorption was also studied, in order to evaluate the feasibility of REs recovery from waters. The adsorption-desorption procedure with the optimized parameters was also tested on a leaching solution obtained by dissolution of a dismantled NdFeB magnet of a hard-disk. The clays were fully characterized after REs adsorption and desorption by means of X-ray powder diffraction (XRPD) and X-ray photoelectron spectroscopy (XPS); the liquid phase was characterized via Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) analyses. The experimental results show that both clays are able to capture and release La and Nd ions, with an ion exchange mechanism. The best total efficiency (capture ≈ 50%, release ≈ 70%) is obtained when the uptake and release processes are performed at pH=5 and pH=1 respectively; in real leached scrap solutions, the uptake is around 40% but release efficiency is strongly decreased passing from a mono-ion system to a real system (from 80% to 5%). Furthermore, a strong matrix effect is found, with the matrix largely affecting both the uptake and the release of neodymium.

  1. Setting Up an Efficient Therapeutic Hypothermia Team in Conscious ST Elevation Myocardial Infarction Patients: A UK Heart Attack Center Experience.

    PubMed

    Islam, Shahed; Hampton-Till, James; MohdNazri, Shah; Watson, Noel; Gudde, Ellie; Gudde, Tom; Kelly, Paul A; Tang, Kare H; Davies, John R; Keeble, Thomas R

    2015-12-01

    Patients presenting with ST elevation myocardial infarction (STEMI) are routinely treated with percutaneous coronary intervention to restore blood flow in the occluded artery to reduce infarct size (IS). However, there is evidence to suggest that the restoration of blood flow can cause further damage to the myocardium through reperfusion injury (RI). Recent research in this area has focused on minimizing damage to the myocardium caused by RI. Therapeutic hypothermia (TH) has been shown to be beneficial in animal models of coronary artery occlusion in reducing IS caused by RI if instituted early in an ischemic myocardium. Data in humans are less convincing to date, although exploratory analyses suggest that there is significant clinical benefit in reducing IS if TH can be administered at the earliest recognition of ischemia in anterior myocardial infarction. The Essex Cardiothoracic Centre is the first UK center to have participated in administering TH in conscious patients presenting with STEMI as part of the COOL-AMI case series study. In this article, we outline our experience of efficiently integrating conscious TH into our primary percutaneous intervention program to achieve 18 minutes of cooling duration before reperfusion, with no significant increase in door-to-balloon times, in the setting of the clinical trial.

  2. The preclinical set-up at the ID17 biomedical beamline to achieve high local dose deposition using interlaced microbeams

    NASA Astrophysics Data System (ADS)

    Bräuer-Krisch, E.; Nemoz, C.; Brochard, Th; Berruyer, G.; Renier, M.; Pouyatos, B.; Serduc, R.

    2013-03-01

    Microbeam Radiation Therapy (MRT) uses spatially a fractionated "white beam" (energies 50-350 keV) irradiation from a Synchrotron Source. The typical microbeams used at ID17 are 25-100μm-thick, spaced by 200-400μm, and carry extremely high dose rates (up to about 16 kGy/s). These microbeams are well tolerated by biological tissue, i.e. up to several hundred of Gy in the peaks. When valley doses, caused by Compton scattering in between two microbeams, remain within a dose regime similar to conventional RT, a superior tumour control can be achieved with MRT than with conventional RT. The normal tissue tolerance of these microscopically small beams is outstanding and well documented in the literature. The hypothesis of a differential effect in particular on the vasculature of normal versus tumoral tissue might best be proven by using large animal models with spontaneous tumors instead of small laboratory animals with transplantable tumors, an ongoing project on ID17. An alternative approach to deposit a high dose, while preserving the feature of the spatial separation of these microbeams outside the target has opened up new applications in preclinical research. The instrumentation of this method to produce such interlaced beams is presented with an outlook on the challenges to build a treatment platform for human patients. Dose measurements using Gafchromic films exposed in interlaced geometries with their steep profiles highlight the potential to deposit radiotoxic doses in the vicinity of radiosensitive tissues.

  3. Use of natural clays as sorbent materials for rare earth ions: Materials characterization and set up of the operative parameters.

    PubMed

    Iannicelli-Zubiani, Elena Maria; Cristiani, Cinzia; Dotelli, Giovanni; Gallo Stampino, Paola; Pelosato, Renato; Mesto, Ernesto; Schingaro, Emanuela; Lacalamita, Maria

    2015-12-01

    Two mineral clays of the montmorillonite group were tested as sorbents for the removal of Rare Earths (REs) from liquid solutions. Lanthanum and neodymium model solutions were used to perform uptake tests in order to: (a) verify the clays sorption capability, (b) investigate the sorption mechanisms and (c) optimize the experimental parameters, such as contact time and pH. The desorption was also studied, in order to evaluate the feasibility of REs recovery from waters. The adsorption-desorption procedure with the optimized parameters was also tested on a leaching solution obtained by dissolution of a dismantled NdFeB magnet of a hard-disk. The clays were fully characterized after REs adsorption and desorption by means of X-ray powder diffraction (XRPD) and X-ray photoelectron spectroscopy (XPS); the liquid phase was characterized via Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) analyses. The experimental results show that both clays are able to capture and release La and Nd ions, with an ion exchange mechanism. The best total efficiency (capture ≈ 50%, release ≈ 70%) is obtained when the uptake and release processes are performed at pH=5 and pH=1 respectively; in real leached scrap solutions, the uptake is around 40% but release efficiency is strongly decreased passing from a mono-ion system to a real system (from 80% to 5%). Furthermore, a strong matrix effect is found, with the matrix largely affecting both the uptake and the release of neodymium. PMID:26403388

  4. Law sets up oceans commission

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    In an anticipated move, U.S. President Bill Clinton on August 7 signed into law the Oceans Act of 2000.The bipartisan legislation, which takes effect on January 20,2001, establishes a commission on ocean policy to examine federal ocean policy and environmental and economic trends affecting oceans and coasts.The act—which grew out of a call issued by Clinton at the National Oceans Conference in Monterey, California in 1998—requires the commission to submit recommendations to Congress and the president within 18 months of its appointment, and for the President to submit proposals to Congress about the use and stewardship of ocean and coastal resources.

  5. New paleomagnetic data from Bornholm granitoids testing whether the East-European Craton rotated during the 1.50-1.45 Ga Danopolonian orogeny

    NASA Astrophysics Data System (ADS)

    Lubnina, N.; Bogdanova, S.; Cecys, A.

    2009-04-01

    According to the palaeogeographic reconstructions, the East-European Craton (EEC) was part of the Palaeo- to Mesoproterozoic supercontinent Nuna / Columbia (Hoffman, 1997; Rogers and Santosh, 2002). Particularly important was the period between 1.5 and 1.3 Ga, when incipient break-up of this supercontinent occurred (Condie, 2002) but the EEC ("Baltica") still remained in close connection with other continental blocks. During the entire Mesoproterozoic, however, the EEC featured different geodynamic regimes in its presently western and eastern parts. In the west, these were convergent, while rifting prevailed in the east (Bogdanova et al., 2008). Previously, paleomagnetic studies of the Mesoproterozoic Ladoga Lake mafic rocks in NE Russia and the Dalarna mafic dykes in Sweden have disclosed a regular trend from the older Dalarna dykes to the younger dolerites of Lake Ladoga, suggesting an anticlockwise rotation of about 20 degrees. That rotation could either have affected the entire EEC as a result of the Danopolonian orogeny at ca. 1.50-1.45 Ga or have been associated with local block-displacement events in the Pasha-Ladoga graben (Lubnina et al., 2005, 2007). In the present study, we have tested these alternative possibilities by carrying out new paleomagnetic studies of Mesoproterozoic granitoids from the Danish island of Bornholm in the South Baltic Sea, which is a key area of the Danopolonian orogeny. On SW Bornholm, the 1.46 Ga Ronne granodiorites, which are cut by NNW trending thin dolerite dykes have been sampled in the Klippelokke quarry. Remanence measurements were performed using a 2G cryogenic magnetometer at the Palaeomagnetic Laboratory of the Department of Geology, Lund University, Sweden. Conventional progressive thermal or alternating field (AF) demagnetizations were applied to all specimens. During the stepwise thermal and AF demagnetization experiments, two components of NRM were isolated in the majority of the granitoid specimens. The low

  6. [Testing the efficacy of disinfectants during drinking water treatment. A new experimental set-up at the German EPA (Umweltbundesamt - UBA)].

    PubMed

    Grützmacher, G; Bartel, H; Althoff, H W; Clemen, S

    2007-03-01

    A set-up for experiments in the flow-through mode was constructed in order to test the efficacy of substances used for disinfecting water during drinking water treatment. A flow-through mode - in contrast to experiments under stationary conditions (so-called batch experiments) - was chosen, because this experimental design allows experiments to be carried out under constant conditions for an extended time (up to one week) and because efficacy testing is possible repeatedly, simultaneously and under exactly the same conditions for short (about 0.5 min) and also longer (about 47 min) contact times. With this experimental design the effect of biofilms along the inner pipe surfaces can be included in the observations. The construction of the experimental set-up is based on experience with laboratory flow-through systems that were installed by the UBA's drinking water department (formerly Institute for Water-, Soil- and Air Hygiene (WaBoLu) Institute) for testing disinfection with chlorine. In the first step, a test pipe for the simulation of a water works situation was installed. Water of different qualities can be mixed in large volumes beforehand so that the experimental procedure can be run with constant water quality for a minimum of one week. The kinetics of the disinfection reaction can be observed by extracting samples from eight sampling ports situated along the test pipe. In order to assign exact residence times to each of the sampling ports, tracer experiments were performed prior to testing disinfectant efficacy. This paper gives the technical details of the experimental set-up and presents the results of the tracer experiments to provide an introduction with respect to its potential.

  7. SU-C-204-06: Surface Imaging for the Set-Up of Proton Post-Mastectomy Chestwall Irradiation: Gated Images Vs Non Gated Images

    SciTech Connect

    Batin, E; Depauw, N; MacDonald, S; Lu, H

    2015-06-15

    Purpose: Historically, the set-up for proton post-mastectomy chestwall irradiation at our institution started with positioning the patient using tattoos and lasers. One or more rounds of orthogonal X-rays at gantry 0° and beamline X-ray at treatment gantry angle were then taken to finalize the set-up position. As chestwall targets are shallow and superficial, surface imaging is a promising tool for set-up and needs to be investigated Methods: The orthogonal imaging was entirely replaced by AlignRT™ (ART) images. The beamline X-Ray image is kept as a confirmation, based primarily on three opaque markers placed on skin surface instead of bony anatomy. In the first phase of the process, ART gated images were used to set-up the patient and the same specific point of the breathing curve was used every day. The moves (translations and rotations) computed for each point of the breathing curve during the first five fractions were analyzed for ten patients. During a second phase of the study, ART gated images were replaced by ART non-gated images combined with real-time monitoring. In both cases, ART images were acquired just before treatment to access the patient position compare to the non-gated CT. Results: The average difference between the maximum move and the minimum move depending on the chosen breathing curve point was less than 1.7 mm for all translations and less than 0.7° for all rotations. The average position discrepancy over the course of treatment obtained by ART non gated images combined to real-time monitoring taken before treatment to the planning CT were smaller than the average position discrepancy obtained using ART gated images. The X-Ray validation images show similar results with both ART imaging process. Conclusion: The use of ART non gated images combined with real time imaging allows positioning post-mastectomy chestwall patients in less than 3 mm / 1°.

  8. A study on contralateral breast surface dose for various tangential field techniques and the impact of set-up error on this dose.

    PubMed

    Prabhakar, R; Haresh, K P; Julka, P K; Ganesh, T; Rath, G K; Joshi, R C; Sasindran, M; Naik, K K; Sridhar, P S

    2007-03-01

    The risk of inducing contralateral breast (CLB) cancer in patients undergoing tangential field irradiation for the treatment of breast cancer is a serious concern in radiation oncology. A bilateral breast phantom made of wax attached onto the Alderson Rando phantom was used for studying the CLB dose for techniques using physical wedges, EDWs, IMRT and open fields. The skin dose to the CLB was measured at four different points (3 cm from the medial border of the tangential field (P1), nipple (P3), axilla (P4), midpoint between P3 and P1 (P2)). The highest measured dose occurred at P1 with the 60 degrees physical wedges; it was 15.3% of the dose at isocentre. Similarly, the dose measured at P3 (nipple) with 60 degrees physical wedges was 1.90 times higher than the dose with 60 degrees EDWs. The dose at P1 for IMRT (7.8%) was almost the same as that for the open field (8.7%). The skin dose measured at the nipple was 2.1 - 10.9 % of the isocentre dose. The highest CLB doses were contributed by medial wedged fields. The dose to the CLB can be reduced by using IMRT or avoiding wedging the medial tangential fields. A set-up error in the longitudinal direction has little impact on the CLB dose. Set-up errors > 1 cm in the vertical and lateral directions have significant impact on the CLB dose. PMID:17508600

  9. Focus stacking: Comparing commercial top-end set-ups with a semi-automatic low budget approach. A possible solution for mass digitization of type specimens

    PubMed Central

    Brecko, Jonathan; Mathys, Aurore; Dekoninck, Wouter; Leponce, Maurice; VandenSpiegel, Didier; Semal, Patrick

    2014-01-01

    Abstract In this manuscript we present a focus stacking system, composed of commercial photographic equipment. The system is inexpensive compared to high-end commercial focus stacking solutions. We tested this system and compared the results with several different software packages (CombineZP, Auto-Montage, Helicon Focus and Zerene Stacker). We tested our final stacked picture with a picture obtained from two high-end focus stacking solutions: a Leica MZ16A with DFC500 and a Leica Z6APO with DFC290. Zerene Stacker and Helicon Focus both provided satisfactory results. However, Zerene Stacker gives the user more possibilities in terms of control of the software, batch processing and retouching. The outcome of the test on high-end solutions demonstrates that our approach performs better in several ways. The resolution of the tested extended focus pictures is much higher than those from the Leica systems. The flash lighting inside the Ikea closet creates an evenly illuminated picture, without struggling with filters, diffusers, etc. The largest benefit is the price of the set-up which is approximately € 3,000, which is 8 and 10 times less than the LeicaZ6APO and LeicaMZ16A set-up respectively. Overall, this enables institutions to purchase multiple solutions or to start digitising the type collection on a large scale even with a small budget. PMID:25589866

  10. Detection performance assessment of hand-held mine detection systems in a procurement process: test set-up for MDs and MD/GPRs

    NASA Astrophysics Data System (ADS)

    Schoolderman, Arnold J.; Roosenboom, Jacques H. J.

    2005-06-01

    The Engineers Centre of Expertise of the Royal Netherlands Army (RNLA) has conducted a study on countermine in peace operations. This study, finished in 2002, concluded that the final solution to countermine will depend in the first place on better detection of buried low-metal mines, e.g. by direct detection of the explosive components in mines. Until such detection systems are available, intermediate solutions are necessary in order to assure freedom of movement in peace operations. Because countermine operations consist of a number of different activities (area preparation, detection, clearance, etc) and the suitability of the different types of available equipment depends on the scenario, the toolbox concept for countermine equipment was adopted. In 2003 a procurement process was started in order to fill this toolbox with commercial-off-the-shelf and military-off-the-shelf equipment. The paper gives a concise description of the study on countermine operations and the procurement process, and subsequently focuses on the set-up of the tests that were conducted in the framework of the procurement of hand-held mine detection systems, like metal detectors and dual-sensor mine detectors. Programs of requirements for these systems were drawn up, aiming at systems for general use and special purpose systems. Blind tests to check the compliancy to the detection performance requirements were designed and conducted in the short timeframe that was available in the procurement process. These tests are discussed in this paper, including the set-up of the test lanes, the targets used and their depths, and the role of the operator. The tests of the capability of the detectors to discriminate small targets adjacent to large targets were conducted according the guidelines of the CEN Workshop Agreement on metal detector tests. Although the results of the tests are commercially confidential, conclusions and lessons learned from the execution of these tests are presented.

  11. Setting Up a Bioluminescence Resonance Energy Transfer High throughput Screening Assay to Search for Protein/Protein Interaction Inhibitors in Mammalian Cells

    PubMed Central

    Couturier, Cyril; Deprez, Benoit

    2012-01-01

    Each step of the cell life and its response or adaptation to its environment are mediated by a network of protein/protein interactions termed “interactome.” Our knowledge of this network keeps growing due to the development of sensitive techniques devoted to study these interactions. The bioluminescence resonance energy transfer (BRET) technique was primarily developed to allow the dynamic monitoring of protein/protein interactions (PPI) in living cells, and has widely been used to study receptor activation by intra- or extra-molecular conformational changes within receptors and activated complexes in mammal cells. Some interactions are described as crucial in human pathological processes, and a new class of drugs targeting them has recently emerged. The BRET method is well suited to identify inhibitors of PPI and here is described why and how to set up and optimize a high throughput screening assay based on BRET to search for such inhibitory compounds. The different parameters to take into account when developing such BRET assays in mammal cells are reviewed to give general guidelines: considerations on the targeted interaction, choice of BRET version, inducibility of the interaction, kinetic of the monitored interaction, and of the BRET reading, influence of substrate concentration, number of cells and medium composition used on the Z′ factor, and expected interferences from colored or fluorescent compounds. PMID:22973258

  12. Awareness assessment of harmful effects of mercury in a health care set-up in India: A survey-based study.

    PubMed

    Halder, Nabanita; Peshin, Sharda Shah; Pandey, Ravindra Mohan; Gupta, Yogendra Kumar

    2015-12-01

    Mercury, one of the most toxic heavy metals, is ubiquitous in environment. The adverse health impact of mercury on living organisms is well known. The health care facilities are one of the important sources of mercury release into the atmosphere as mercury items are extensively used in hospitals. To assess the awareness about mercury toxicity and the knowledge of proper handling and disposal of mercury-containing items in health care set-up, a questionnaire-based survey was carried out amongst doctors (n = 835), nurses (n = 610) and technicians (n = 393) in government hospitals, corporate hospitals and primary health care centres in the Indian states of Delhi, Uttar Pradesh and Haryana. The study was conducted using a tool-containing pretested structured multiple-choice questionnaire. Analysis of the results using STATA 11.1 software highlighted that overall awareness was more in corporate sector. However, percentage range of knowledge of respondents irrespective of health care sector was only between 20 and 40%. Despite the commitment of various hospitals to be mercury free, mercury containing-thermometer/sphygmomanometer are still preferred by health professionals. The likely reasons are availability, affordability, accuracy and convenience in use. There is an urgent need for source reduction, recycling and waste minimization. Emphasis must be laid on mercury alternative products, education and training of health personnel and public at large, about correct handling and proper clean up of spills.

  13. Cold test with a benchtop set-up for fluidized bed reactor using quartz sand to simulate gasification of coal cokes by concentrated solar radiation

    NASA Astrophysics Data System (ADS)

    Gokon, Nobuyuki; Tanabe, Tomoaki; Shimizu, Tadaaki; Kodama, Tatsuya

    2016-05-01

    The impacts of internal circulation of a mixture of coal-coke particles and quartz sand on the fluidization state in a fluidized bed reactor are investigated by a cold test with a benchtop set-up in order to design 10-30 kWth scale prototype windowed fluidized-bed reactor. Firstly, a basic relationship between pressure loss of inlet gas and gas velocity was experimentally examined using quartz sand with different particle sizes by a small-scale quartz tube with a distributor at ambient pressure and temperature. Based on the results, an appropriate particle range of quartz sand and layer height/layer diameter ratio (L/D ratio) was determined for a design of the fluidized bed reactor. Secondly, a windowed reactor mock-up was designed and fabricated for solar coke gasification using quartz sand as a bed material. The pressure loss between the inlet and outlet gases was examined, and descending cokes and sand particles on the sidewall of the reactor was observed in the reactor mock-up. The moving velocity and distance of descending particles/sands from the top to bottom of fluidized bed were measured by the visual observation of the colored tracer particles on outside wall of the reactor.

  14. A Controlled Design of Aligned and Random Nanofibers for 3D Bi-functionalized Nerve Conduits Fabricated via a Novel Electrospinning Set-up

    PubMed Central

    Kim, Jeong In; Hwang, Tae In; Aguilar, Ludwig Erik; Park, Chan Hee; Kim, Cheol Sang

    2016-01-01

    Scaffolds made of aligned nanofibers are favorable for nerve regeneration due to their superior nerve cell attachment and proliferation. However, it is challenging not only to produce a neat mat or a conduit form with aligned nanofibers but also to use these for surgical applications as a nerve guide conduit due to their insufficient mechanical strength. Furthermore, no studies have been reported on the fabrication of aligned nanofibers and randomly-oriented nanofibers on the same mat. In this study, we have successfully produced a mat with both aligned and randomly-oriented nanofibers by using a novel electrospinning set up. A new conduit with a highly-aligned electrospun mat is produced with this modified electrospinning method, and this proposed conduit with favorable features, such as selective permeability, hydrophilicity and nerve growth directional steering, were fabricated as nerve guide conduits (NGCs). The inner surface of the nerve conduit is covered with highly aligned electrospun nanofibers and is able to enhance the proliferation of neural cells. The central part of the tube is double-coated with randomly-oriented nanofibers over the aligned nanofibers, strengthening the weak mechanical strength of the aligned nanofibers. PMID:27021221

  15. Validation of an original incubator set-up for the exposure of human astrocyte cells to X-band microwaves in a GTEM-chamber.

    PubMed

    Pérez-Bruzón, R N; Del Moral, A; Pérez-Castejón, C; Llorente, M; Vera, A; Azanza, M J

    2011-09-01

    A current concern about the biological effects of electromagnetic fields (EMF) is increasing with the wide spread use of X-band microwaves (MW, 8-10 GHz range). Gigahertz transverse electromagnetic (GTEM) field flat transmission lines are currently being used for experimental exposure of biological samples to high frequency EMF. Experiments carried out on human cells in culture require optimal growing temperature conditions, i.e. 37 °C, 5% CO2 in a humidified atmosphere. The aim of our work has been: i) to built up an original incubator set-up, the so called GTEM-incubator, for exposure of human cells in culture to MW inside a GTEM-chamber, under optimal growing physical conditions; ii) to make the validation of the GTEM-incubator by growing cell samples inside the non-energized GTEM-chamber (test sample) comparing the results with the ones obtained from cell samples grown inside a standard incubator (control samples). The features for comparison were: cell morphology, expression and distribution of cytoskeleton proteins, genotoxicity, viability and cell cycle progression. Any variation in any of the studied parameters would allow for detecting any possible failure or misconception in our GTEM-incubator working test. The results obtained in control and test incubators showed non-significant differences in the development of both cell populations for any of the studied parameters. Thereby our GTEM-incubator is considered valid for our purposes of human cell exposures to X-band MW.

  16. Experimental illumination of natural habitat—an experimental set-up to assess the direct and indirect ecological consequences of artificial light of different spectral composition

    PubMed Central

    Spoelstra, Kamiel; van Grunsven, Roy H. A.; Donners, Maurice; Gienapp, Phillip; Huigens, Martinus E.; Slaterus, Roy; Berendse, Frank; Visser, Marcel E.; Veenendaal, Elmar

    2015-01-01

    Artificial night-time illumination of natural habitats has increased dramatically over the past few decades. Generally, studies that assess the impact of artificial light on various species in the wild make use of existing illumination and are therefore correlative. Moreover, studies mostly focus on short-term consequences at the individual level, rather than long-term consequences at the population and community level—thereby ignoring possible unknown cascading effects in ecosystems. The recent change to LED lighting has opened up the exciting possibility to use light with a custom spectral composition, thereby potentially reducing the negative impact of artificial light. We describe here a large-scale, ecosystem-wide study where we experimentally illuminate forest-edge habitat with different spectral composition, replicated eight times. Monitoring of species is being performed according to rigid protocols, in part using a citizen-science-based approach, and automated where possible. Simultaneously, we specifically look at alterations in behaviour, such as changes in activity, and daily and seasonal timing. In our set-up, we have so far observed that experimental lights facilitate foraging activity of pipistrelle bats, suppress activity of wood mice and have effects on birds at the community level, which vary with spectral composition. Thus far, we have not observed effects on moth populations, but these and many other effects may surface only after a longer period of time. PMID:25780241

  17. Experimental and Numerical Investigation of Mixed-Mode Interlaminar Fracture of Carbon-Polyester Laminated Woven Composite by Using Arcan Set-up

    NASA Astrophysics Data System (ADS)

    Heydari, Mohammad Hossein; Choupani, Naghdali; Shameli, Moharram

    2011-12-01

    Composite materials are widely used in marine, aerospace and automobile industries. These materials are often subjected to defects and damages from both in-service and manufacturing process. Delamination is the most important of these defects. This paper reports investigation of mixed-mode fracture toughness in carbon-polyester composite by using numerical and experimental methods. All tests were performed by Arcan set-up. By changing the loading angle, α, from 0° to 90° at 15° intervals, mode-I, mixed-mode and mode-II fracture data were obtained. Correction factors for various conditions were obtained by using ABAQUS software. Effects of the crack length and the loading angle on fracture were also studied. The interaction j-integral method was used to separate the mixed-mode stress intensity factors at the crack tip under different loading conditions. As the result, it can be seen that the shearing mode interlaminar fracture toughness is larger than the opening mode interlaminar fracture toughness. This means that interlaminar cracked specimen is tougher in shear loading condition and weaker in tensile loading condition.

  18. Measurement of maximum skin dose in interventional radiology and cardiology and challenges in the set-up of European alert thresholds.

    PubMed

    Farah, J; Trianni, A; Carinou, E; Ciraj-Bjelac, O; Clairand, I; Dabin, J; De Angelis, C; Domienik, J; Jarvinen, H; Kopec, R; Majer, M; Malchair, F; Negri, A; Novák, L; Siiskonen, T; Vanhavere, F; Knežević, Ž

    2015-04-01

    To help operators acknowledge patient dose during interventional procedures, EURADOS WG-12 focused on measuring patient skin dose using XR-RV3 gafchromic films, thermoluminescent detector (TLD) pellets or 2D TL foils and on investigating possible correlation to the on-line dose indicators such as fluoroscopy time, Kerma-area product (KAP) and cumulative air Kerma at reference point (CK). The study aims at defining non-centre-specific European alert thresholds for skin dose in three interventional procedures: chemoembolization of the liver (CE), neuroembolization (NE) and percutaneous coronary interventions (PCI). Skin dose values of >3 Gy (ICRP threshold for skin injuries) were indeed measured in these procedures confirming the need for dose indicators that correlate with maximum skin dose (MSD). However, although MSD showed fairly good correlation with KAP and CK, several limitations were identified challenging the set-up of non-centre-specific European alert thresholds. This paper presents preliminary results of this wide European measurement campaign and focuses on the main challenges in the definition of European alert thresholds.

  19. A novel 15N tracer approach for the quantification of N2 and N2O emissions from soil incubations in a completely automated laboratory set up

    NASA Astrophysics Data System (ADS)

    Scheer, Clemens; Dannenmann, Michael; Meier, Rudolf

    2015-04-01

    The microbial mediated production of nitrous oxide (N2O) and its reduction to dinitrogen (N2) via denitrification represents a loss of nitrogen (N) from fertilised agro-ecosystems to the atmosphere. Although denitrification has received great interest by biogeochemists in the last decades, the magnitude of N2lossesand related N2:N2O ratios from soils still are largely unknown due to methodical constraints. We present a novel 15N tracer approach, based on a previous developed tracer method to study denitrification in pure bacterial cultures which was modified for the use on soil incubations in a completely automated laboratory set up. The method uses a background air in the incubation vessels that is replaced with a helium-oxygen gas mixture with a 50-fold reduced N2 background (2 % v/v). This method allows for a direct and sensitive quantification of the N2 and N2O emissions from the soil with isotope-ratio mass spectrometry after 15N labelling of denitrification N substrates and minimises the sensitivity to the intrusion of atmospheric N2 at the same time. The incubation set up was used to determine the influence of different soil moisture levels on N2 and N2O emissions from a sub-tropical pasture soil in Queensland/Australia. The soil was labelled with an equivalent of 50 μg-N per gram dry soil by broadcast application of KNO3solution (4 at.% 15N) and incubated for 3 days at 80% and 100% water filled pore space (WFPS), respectively. The headspace of the incubation vessel was sampled automatically over 12hrs each day and 3 samples (0, 6, and 12 hrs after incubation start) of headspace gas analysed for N2 and N2O with an isotope-ratio mass spectrometer (DELTA V Plus, Thermo Fisher Scientific, Bremen, Germany(. In addition, the soil was analysed for 15N NO3- and NH4+ using the 15N diffusion method, which enabled us to obtain a complete N balance. The method proved to be highly sensitive for N2 and N2O emissions detecting N2O emissions ranging from 20 to 627 μN kg

  20. SU-E-J-172: Bio-Physical Effects of Patients Set-Up Errors According to Whole Breast Irradiation Techniques

    SciTech Connect

    Lee, S; Suh, T; Park, S; Kim, M; Lee, M; Park, J

    2015-06-15

    Purpose: The dose-related effects of patient setup errors on biophysical indices were evaluated for conventional wedge (CW) and field-in-field (FIF) whole breast irradiation techniques. Methods: The treatment plans for 10 patients receiving whole left breast irradiation were retrospectively selected. Radiobiological and physical effects caused by dose variations were evaluated by shifting the isocenters and gantry angles of the treatment plans. Dose-volume histograms of the planning target volume (PTV), heart, and lungs were generated, and conformity index (CI), homogeneity index (HI), tumor control probability (TCP), and normal tissue complication probability (NTCP) were determined. Results: For “isocenter shift plan” with posterior direction, the D95 of the PTV decreased by approximately 15% and the TCP of the PTV decreased by approximately 50% for the FIF technique and by 40% for the CW; however, the NTCPs of the lungs and heart increased by about 13% and 1%, respectively, for both techniques. Increasing the gantry angle decreased the TCPs of the PTV by 24.4% (CW) and by 34% (FIF). The NTCPs for the two techniques differed by only 3%. In case of CW, the CIs and HIs were much higher than that of the FIF in all cases. It had a significant difference between two techniques (p<0.01). According to our results, however, the FIF had more sensitive response by set up errors rather than CW in bio-physical aspects. Conclusions: The radiobiological-based analysis can detect significant dosimetric errors then, can provide a practical patient quality assurance method to guide the radiobiological and physical effects.

  1. Analysis of sewage sludge using an experimental prompt gamma neutron activation analysis (pgnaa) set-up with an am-be source

    NASA Astrophysics Data System (ADS)

    Idiri, Z.; Redjem, F.; Beloudah, N.

    2016-09-01

    An experimental PGNAA set-up using a 1 Ci Am-Be source has been developed and used for analysis of bulk sewage sludge samples issued from a wastewater treatment plant situated in an industrial area of Algiers. The sample dimensions were optimized using thermal neutron flux calculations carried out with the MCNP5 Monte Carlo Code. A methodology is then proposed to perform quantitative analysis using the absolute method. For this, average thermal neutron flux inside the sludge samples is deduced using average thermal neutron flux in reference water samples and thermal flux measurements with the aid of a 3He neutron detector. The average absolute gamma detection efficiency is determined using the prompt gammas emitted by chlorine dissolved in a water sample. The gamma detection efficiency is normalized for sludge samples using gamma attenuation factors calculated with the MCNP5 code for water and sludge. Wet and dehydrated sludge samples were analyzed. Nutritive elements (Ca, N, P, K) and heavy metals elements like Cr and Mn were determined. For some elements, the PGNAA values were compared to those obtained using Atomic Absorption Spectroscopy (AAS) and Inductively Coupled Plasma (ICP) methods. Good agreement is observed between the different values. Heavy element concentrations are very high compared to normal values; this is related to the fact that the wastewater treatment plant is treating not only domestic but also industrial wastewater that is probably rejected by industries without removal of pollutant elements. The detection limits for almost all elements of interest are sufficiently low for the method to be well suited for such analysis.

  2. An experimental set-up to apply polarization modulation to infrared reflection absorption spectroscopy for improved in situ studies of atmospheric corrosion processes

    SciTech Connect

    Wiesinger, R.; Schade, U.; Kleber, Ch.; Schreiner, M.

    2014-06-15

    A new set-up for improved monitoring of atmospheric corrosion processes in situ and in real-time is presented. To characterize chemical structures of thin films on metal surfaces surface sensitive analytical techniques are required. One possible technique is Infrared Reflection Absorption Spectroscopy (IRRAS) which has become an established method to investigate surface corrosion films of thicknesses less than 200 nm. However, there are limitations related to the sensitivity of these measurements, in case of investigating ultrathin films or absorption bands of interest, surface species are superimposed by atmospheric background absorption, which changes during in situ measurements in ambient atmospheres. These difficulties of in situ surface reflection measurements can be eliminated by availing the polarization selectivity of adsorbed surface species. At grazing angles of incidence the absorption of p-polarized infrared radiation by thin surface films on metals is enhanced, while the absorption of s-polarized light by this film is nearly zero. This different behavior of the polarization properties leads to strong selection rules at the surface and can therefore be used to identify molecules adsorbed on metal surfaces. Polarization Modulation (PM) of the infrared (IR) light takes advantage of this disparity of polarization on sample surfaces and in combination with IRRAS yielding a very sensitive and surface-selective method for obtaining IR spectra of ultra-thin films on metal surfaces. An already existing in situ IRRAS/Quartz Crystal Microbalance weathering cell was combined with PM and evaluated according to its applicability to study in situ atmospheric corrosion processes. First real-time measurements on silver samples exposed to different atmospheres were performed showing the advantage of PM-IRRAS compared to conventional IRRAS for such investigations.

  3. Lessons learned from setting up the Nahuche Health and Demographic Surveillance System in the resource-constrained context of northern Nigeria

    PubMed Central

    Alabi, Olatunji; Doctor, Henry V.; Afenyadu, Godwin Y.; Findley, Sally E.

    2014-01-01

    Background The present time reflects a period of intense effort to get the most out of public health interventions, with an emphasis on health systems reform and implementation research. Population health approaches to determine which combinations are better at achieving the goals of improved health and well-being are needed to provide a ready response to the need for timely and real-world piloting of promising interventions. Objective This paper describes the steps needed to establish a population health surveillance site in order to share the lessons learned from our experience launching the Nahuche Health and Demographic Surveillance System (HDSS) in a relatively isolated, rural district in Zamfara, northern Nigeria, where strict Muslim observance of gender separation and seclusion of women must be respected by any survey operation. Discussion Key to the successful launch of the Nahuche HDSS was the leadership's determination, stakeholder participation, support from state and local government areas authorities, technical support from the INDEPTH Network, and international academic partners. Solid funding from our partner health systems development programme during the launch period was also essential, and provided a base from which to secure long-term sustainable funding. Perhaps the most difficult challenges were the adaptations needed in order to conduct the requisite routine population surveillance in the communities, where strict Muslim observance of gender separation and seclusion of women, especially young women, required recruitment of female interviewers, which was in turn difficult due to low female literacy levels. Local community leaders were key in overcoming the population's apprehension of the fieldwork and modern medicine, in general. Continuous engagement and sensitisation of all stakeholders was a critical step in ensuring sustainability. While the experiences of setting up a new HDSS site may vary globally, the experiences in northern Nigeria

  4. The eastern Gulf of Aden: A case study for the setting up of the deep-sea gravity sedimentation on a young continental margin

    NASA Astrophysics Data System (ADS)

    Baurion, Celine; Zaragosi, Sebastien; Leroy, Sylvie; Gorini, Christian; Lucazeau, Francis; Migeon, Sebastien; Garlan, Thierry

    2013-04-01

    The study of sedimentary processes across a young and segmented passive margin under the influence of the Asian monsoon-climate, provide a potential record of tectonic, climatic and high-resolution eustatic events. The northern margin of the eastern Gulf of Aden is one of the world rare examples to study the setting up of gravity sedimentation in a deep basin and the related control parameters. Using multibeam data, Chirp profiles, and sediment cores, we show that this gravity sedimentation highlights the importance of flooding of wadis on the sediment transfer from onshore to the deep basin. The drainage network is not mature on this starved margin, which is affected by post-rift uplift. The main channelized turbidite systems are localized in the western part of the margin, while mass-transport deposits and sheet turbidite deposits are concentrated along the eastern part of the margin affected by a late post-rift uplift. The deep-basin sedimentation is composed of many coarse-grained carbonate turbidites that are related to the lithology of the onshore sedimentary cover. The central part of the uplifted margin does not exhibit coarse-grained turbidites since about 70 ka BP, while the eastern part displays turbidites until recently. This monsoon-influenced margin is characterized by strong along-strike variability in tectonics and fluvial input distribution that might directly influence and segment the gravity sedimentation: (i) the western channelized turbidite system formation depend mainly of the wide catchment area onshore in combination with the geometry of the deep basin; (ii) the starved part of the margin, characterized by mass-transport deposits is mainly controlled by the post-rift uplift; (iii) along the eastern part of the uplifted margin, the unchannelized turbidite deposits seem to be primarily controlled by the presence of a well-developed continental shelf combined to the late uplift impact on the sedimentary supply.

  5. An experimental set-up to apply polarization modulation to infrared reflection absorption spectroscopy for improved in situ studies of atmospheric corrosion processes.

    PubMed

    Wiesinger, R; Schade, U; Kleber, Ch; Schreiner, M

    2014-06-01

    A new set-up for improved monitoring of atmospheric corrosion processes in situ and in real-time is presented. To characterize chemical structures of thin films on metal surfaces surface sensitive analytical techniques are required. One possible technique is Infrared Reflection Absorption Spectroscopy (IRRAS) which has become an established method to investigate surface corrosion films of thicknesses less than 200 nm. However, there are limitations related to the sensitivity of these measurements, in case of investigating ultrathin films or absorption bands of interest, surface species are superimposed by atmospheric background absorption, which changes during in situ measurements in ambient atmospheres. These difficulties of in situ surface reflection measurements can be eliminated by availing the polarization selectivity of adsorbed surface species. At grazing angles of incidence the absorption of p-polarized infrared radiation by thin surface films on metals is enhanced, while the absorption of s-polarized light by this film is nearly zero. This different behavior of the polarization properties leads to strong selection rules at the surface and can therefore be used to identify molecules adsorbed on metal surfaces. Polarization Modulation (PM) of the infrared (IR) light takes advantage of this disparity of polarization on sample surfaces and in combination with IRRAS yielding a very sensitive and surface-selective method for obtaining IR spectra of ultra-thin films on metal surfaces. An already existing in situ IRRAS/Quartz Crystal Microbalance weathering cell was combined with PM and evaluated according to its applicability to study in situ atmospheric corrosion processes. First real-time measurements on silver samples exposed to different atmospheres were performed showing the advantage of PM-IRRAS compared to conventional IRRAS for such investigations.

  6. An experimental set-up to apply polarization modulation to infrared reflection absorption spectroscopy for improved in situ studies of atmospheric corrosion processes

    NASA Astrophysics Data System (ADS)

    Wiesinger, R.; Schade, U.; Kleber, Ch.; Schreiner, M.

    2014-06-01

    A new set-up for improved monitoring of atmospheric corrosion processes in situ and in real-time is presented. To characterize chemical structures of thin films on metal surfaces surface sensitive analytical techniques are required. One possible technique is Infrared Reflection Absorption Spectroscopy (IRRAS) which has become an established method to investigate surface corrosion films of thicknesses less than 200 nm. However, there are limitations related to the sensitivity of these measurements, in case of investigating ultrathin films or absorption bands of interest, surface species are superimposed by atmospheric background absorption, which changes during in situ measurements in ambient atmospheres. These difficulties of in situ surface reflection measurements can be eliminated by availing the polarization selectivity of adsorbed surface species. At grazing angles of incidence the absorption of p-polarized infrared radiation by thin surface films on metals is enhanced, while the absorption of s-polarized light by this film is nearly zero. This different behavior of the polarization properties leads to strong selection rules at the surface and can therefore be used to identify molecules adsorbed on metal surfaces. Polarization Modulation (PM) of the infrared (IR) light takes advantage of this disparity of polarization on sample surfaces and in combination with IRRAS yielding a very sensitive and surface-selective method for obtaining IR spectra of ultra-thin films on metal surfaces. An already existing in situ IRRAS/Quartz Crystal Microbalance weathering cell was combined with PM and evaluated according to its applicability to study in situ atmospheric corrosion processes. First real-time measurements on silver samples exposed to different atmospheres were performed showing the advantage of PM-IRRAS compared to conventional IRRAS for such investigations.

  7. Fish welfare assurance system: initial steps to set up an effective tool to safeguard and monitor farmed fish welfare at a company level.

    PubMed

    van de Vis, J W; Poelman, M; Lambooij, E; Bégout, M-L; Pilarczyk, M

    2012-02-01

    The objective was to take a first step in the development of a process-oriented quality assurance (QA) system for monitoring and safeguarding of fish welfare at a company level. A process-oriented approach is focused on preventing hazards and involves establishment of critical steps in a process that requires careful control. The seven principles of the Hazard Analysis Critical Control Points (HACCP) concept were used as a framework to establish the QA system. HACCP is an internationally agreed approach for management of food safety, which was adapted for the purpose of safeguarding and monitoring the welfare of farmed fish. As the main focus of this QA system is farmed fish welfare assurance at a company level, it was named Fish Welfare Assurance System (FWAS). In this paper we present the initial steps of setting up FWAS for on growing of sea bass (Dicentrarchus labrax), carp (Cyprinus carpio) and European eel (Anguilla anguilla). Four major hazards were selected, which were fish species dependent. Critical Control Points (CCPs) that need to be controlled to minimize or avoid the four hazards are presented. For FWAS, monitoring of CCPs at a farm level is essential. For monitoring purposes, Operational Welfare Indicators (OWIs) are needed to establish whether critical biotic, abiotic, managerial and environmental factors are controlled. For the OWIs we present critical limits/target values. A critical limit is the maximum or minimum value to which a factor must be controlled at a critical control point to prevent, eliminate or reduce a hazard to an acceptable level. For managerial factors target levels are more appropriate than critical limits. Regarding the international trade of farmed fish products, we propose that FWAS needs to be standardized in aquaculture chains. For this standardization a consensus on the concept of fish welfare, methods to assess welfare objectively and knowledge on the needs of farmed fish are required.

  8. Accuracy and efficiency of an infrared based positioning and tracking system for patient set-up and monitoring in image guided radiotherapy

    NASA Astrophysics Data System (ADS)

    Jia, Jing; Xu, Gongming; Pei, Xi; Cao, Ruifen; Hu, Liqin; Wu, Yican

    2015-03-01

    An infrared based positioning and tracking (IPT) system was introduced and its accuracy and efficiency for patient setup and monitoring were tested for daily radiotherapy treatment. The IPT system consists of a pair of floor mounted infrared stereoscopic cameras, passive infrared markers and tools used for acquiring localization information as well as a custom controlled software which can perform the positioning and tracking functions. The evaluation of IPT system characteristics was conducted based on the AAPM 147 task report. Experiments on spatial drift and reproducibility as well as static and dynamic localization accuracy were carried out to test the efficiency of the IPT system. Measurements of known translational (up to 55.0 mm) set-up errors in three dimensions have been performed on a calibration phantom. The accuracy of positioning was evaluated on an anthropomorphic phantom with five markers attached to the surface; the precision of the tracking ability was investigated through a sinusoidal motion platform. For the monitoring of the respiration, three volunteers contributed to the breathing testing in real time. The spatial drift of the IPT system was 0.65 mm within 60 min to be stable. The reproducibility of position variations were between 0.01 and 0.04 mm. The standard deviation of static marker localization was 0.26 mm. The repositioning accuracy was 0.19 mm, 0.29 mm, and 0.53 mm in the left/right (L/R), superior/inferior (S/I) and anterior/posterior (A/P) directions, respectively. The measured dynamic accuracy was 0.57 mm and discrepancies measured for the respiratory motion tracking was better than 1 mm. The overall positioning accuracy of the IPT system was within 2 mm. In conclusion, the IPT system is an accurate and effective tool for assisting patient positioning in the treatment room. The characteristics of the IPT system can successfully meet the needs for real time external marker tracking and patient positioning as well as respiration

  9. Polymerization of rod-like macromolecular monomers studied by stopped-flow, multiangle light scattering: set-up, data processing, and application to fibrin formation.

    PubMed Central

    Bernocco, S; Ferri, F; Profumo, A; Cuniberti, C; Rocco, M

    2000-01-01

    Many biological supramolecular structures are formed by polymerization of macromolecular monomers. Light scattering techniques can provide structural information from such systems, if suitable procedures are used to collect the data and then to extract the relevant parameters. We present an experimental set-up in which a commercial multiangle laser light scattering photometer is linked to a stopped-flow mixer, allowing, in principle, the time-resolved extrapolation of the weight-average molecular weight M(w) and of the z-average square radius of gyration (z) of the polymers from Zimm-like plots. However, if elongated structures are formed as the polymerization proceeds, curved plots rapidly arise, from which M(w) and (z) cannot be recovered by linear fitting. To verify the correctness of a polynomial fitting procedure, polydisperse collections of rod-like or worm-like particles of different lengths, generated at various stages during bifunctional polycondensations of rod-like macromolecular monomers, were considered. Then, the angular dependence of their time-averaged scattered intensity was calculated in the Rayleigh-Gans-Debye approximation, with random and systematic noise also added to the data. For relatively narrow size distributions, a third-degree polynomial fitting gave satisfactory results across a broad range of conversion degrees, yielding M(w) and (z) values within 2% and no greater than 10-20%, respectively, of the calculated values. When more broad size distributions were analyzed, the procedure still performed well for semiflexible polymers, but started to seriously underestimate both M(w) and (z) when rigid rod-like particles were analyzed, even at relatively low conversion degrees. The data were also analyzed in the framework of the Casassa approximation, from which the mass per unit length of the polymers can be derived. These procedures were applied to a set of data taken on the early stages of the thrombin

  10. Options in Education, Transcript for February 16, 1976: National Commitment to Equal Rights & Equal Educational Opportunity, Racial Conflict in the Classroom, Setting Up a Publishing Business, and Women in Education (Mathematics and Sex).

    ERIC Educational Resources Information Center

    George Washington Univ., Washington, DC. Inst. for Educational Leadership.

    "Options in Education" is a radio news program which focuses on issues and developments in education. This transcript contains discussions of the national commitment to desegregated education, racial conflict in the classroom, learning how to set up a publishing business, women in education (mathematics and sex) and education news highlights.…

  11. Guidelines for Setting Up an Extended Field Trip to Florida and the Florida Keys: An Interactive Experiential Training Field Biology Program Consisting of Pretrip Instruction, Search Image Training, Field Exercises, and Observations of Tropical Habitats and Coral Reefs.

    ERIC Educational Resources Information Center

    Baker, Claude D.; And Others

    The importance of experiential aspects of biological study is addressed using multi-dimensional classroom and field classroom approaches to student learning. This document includes a guide to setting up this style of field experience. Several teaching innovations are employed to introduce undergraduate students to the literature, techniques, and…

  12. Setting up a wide panel of patient-derived tumor xenografts of non-small cell lung cancer by improving the preanalytical steps.

    PubMed

    Ilie, Marius; Nunes, Manoel; Blot, Lydia; Hofman, Véronique; Long-Mira, Elodie; Butori, Catherine; Selva, Eric; Merino-Trigo, Ana; Vénissac, Nicolas; Mouroux, Jérôme; Vrignaud, Patricia; Hofman, Paul

    2015-02-01

    With the ongoing need to improve therapy for non-small cell lung cancer (NSCLC) there has been increasing interest in developing reliable preclinical models to test novel therapeutics. Patient-derived tumor xenografts (PDX) are considered to be interesting candidates. However, the establishment of such model systems requires highly specialized research facilities and introduces logistic challenges. We aimed to establish an extensive well-characterized panel of NSCLC xenograft models in the context of a long-distance research network after careful control of the preanalytical steps. One hundred fresh surgically resected NSCLC specimens were shipped in survival medium at room temperature from a hospital-integrated biobank to animal facilities. Within 24 h post-surgery, tumor fragments were subcutaneously xenografted into immunodeficient mice. PDX characterization was performed by histopathological, immunohistochemical, aCGH and next-generation sequencing approaches. For this model system, the tumor take rate was 35%, with higher rates for squamous carcinoma (60%) than for adenocarcinoma (13%). Patients for whom PDX tumors were obtained had a significantly shorter disease-free survival (DFS) compared to patients for whom no PDX tumors (P = 0.039) were obtained. We established a large panel of PDX NSCLC models with a high frequency of mutations (29%) in EGFR, KRAS, NRAS, MEK1, BRAF, PTEN, and PI3KCA genes and with gene amplification (20%) of c-MET and FGFR1. This new patient-derived NSCLC xenograft collection, established regardless of the considerable time required and the distance between the clinic and the animal facilities, recapitulated the histopathology and molecular diversity of NSCLC and provides stable and reliable preclinical models for human lung cancer research.

  13. 7 CFR Exhibit J to Subpart A of... - Manufactured Home Sites, Rental Projects and Subdivisions: Development, Installation and Set-Up

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CONSTRUCTION AND REPAIR Planning and Performing Construction and Other Development Pt. 1924, Subpt. A, Exh. J... One- and Two-Family Dwellings or Model Building Codes acceptable to FmHA or its successor agency under... the economical and orderly development and utilization of land for planning and development...

  14. Field-based density measurements as tool to identify preeruption dome structure: set-up and first results from Unzen volcano, Japan

    NASA Astrophysics Data System (ADS)

    Kueppers, Ulrich; Scheu, Bettina; Spieler, Oliver; Dingwell, Donald B.

    2005-03-01

    For an improvement in the quality of conduit flow and dome-related explosive eruption models, knowledge of the preeruption or precollapse density of the rocks involved is necessary. As close investigation is impossible during eruption, the best substitute comes from quantitative investigation of the eruption deposits. The porosity of volcanic rocks is of primary importance for the eruptive behaviour and, accordingly, a key-parameter for realistic models of dome stability and conduit flow. Fortunately, this physical property may be accurately determined via density measurements. We developed a robust, battery-powered device for rapid and reliable density measurements of dry rock samples in the field. The density of the samples (sealed in plastic bags at 250 mbar) is determined using the Archimedean principle. We have tested the device on the deposits of the 1990-1995 eruption of Unzen volcano, Japan. Short setup and operation times allow up to 60 measurements per day under fieldwork conditions. The rapid accumulation of correspondingly large data sets has allowed us to acquire the first statistically significant data set of clast density distribution in block-and-ash flow deposits. More than 1100 samples with a total weight of 2.2 tons were measured. The data set demonstrates that the deposits of the last eruptive episode at Unzen display a bimodal density distribution, with peaks at 2.0±0.1 and 2.3±0.1 g/cm 3, corresponding to open porosity values of 20 and 8 vol.%, respectively. We use this data set to link the results of laboratory-based fragmentation experiments to field studies at recently active lava domes.

  15. The FAMoUS toolbox goes to Yasur: field test of a FAst, MUltiparametric Set-up for real-time observation of explosive eruptions

    NASA Astrophysics Data System (ADS)

    Freda, C.; Taddeucci, J.; Scarlato, P.; Rao, S.; Salvaterra, C.; Gaeta, M.; Palladino, D. M.

    2012-04-01

    juvenile vs. lithic bombs. 3) The generation and propagation of acoustic and shock waves was visualized in large-field videos and compared with microphone recordings. 4) The settling velocity of ash- to lapilli-sized pyroclasts was measured using high-speed videos, to be coupled with the thermal information on respective plumes and component/size distribution of collected samples. Results from this first test illustrate the potential of FAMoUS for, e.g.,: i) tracking pyroclast ejection velocity and jet-plume development at a broad range of volcanic eruptions; ii) interpreting signals from infrasonic monitoring networks; iii) illuminating the development and thermal history of pyroclastic density currents; and iv) measuring the settling velocity and sedimentation rate of fallout pyroclasts [1]. Fast deploying and portability of FAMoUS could enhance the quasi-real time incorporation of such information into hazard mitigation eruption models. [1] Taddeucci et al. (2011) Geology, 39; 891-894.

  16. The FAMoUS toolbox goes to Yasur: field test of a FAst, MUltiparametric Set-up for real-time observation of explosive eruptions

    NASA Astrophysics Data System (ADS)

    Taddeucci, J.; Freda, C.; Scarlato, P.; Rao, S.; Salvaterra, C.; Gaeta, M.; Palladino, D. M.

    2011-12-01

    juvenile vs. lithic bombs. 3) The generation and propagation of acoustic and shock waves was visualized in large-field videos and compared with microphone recordings. 4) The settling velocity of ash- to lapilli-sized pyroclasts was measured using high-speed videos, to be coupled with the thermal information on respective plumes and component/size distribution of collected samples. Results from this first test illustrate the potential of FAMoUS for, e.g.: i) tracking pyroclast ejection velocity and jet-plume development at a broad range of volcanic eruptions; ii) interpreting signals from infrasonic monitoring networks; iii) illuminating the development and thermal history of pyroclastic density currents; and iv) measuring the settling velocity and sedimentation rate of fallout pyroclasts [1]. Fast deploying and portability of FAMoUS could enhance the quasi-real time incorporation of such information into hazard mitigation eruption models. [1] Taddeucci et al. (2011) Geology, 39; 891-894.

  17. Setting up of ambulatory hysteroscopy service.

    PubMed

    Kolhe, Shilpa

    2015-10-01

    There is an obvious trend towards developing ambulatory procedures in gynaecology with ambulatory hysteroscopy as its mainstay. In the recent years, the fast pace of modern technological advances in gynaecologic endoscopy, and particularly in the field of hysteroscopy, have been both thrilling and spectacular. Despite this, the uptake of operative hysteroscopy in ambulatory settings has been relatively slow. There is some apprehension amongst gynaecologists to embark on therapeutic outpatient hysteroscopy, and an organisational change is required to alter the mindset. Although there are best practice guidelines for outpatient hysteroscopy, there are unresolved issues around adequate training and accreditation of future hysteroscopists. Virtual-reality simulation training for operative hysteroscopy has shown promising preliminary results, and it is being aggressively evaluated and validated. This review article is an attempt to provide a useful practical guide to all those who wish to implement ambulatory hysteroscopy services in their outpatient departments. PMID:25979350

  18. [Setting up situated learning in vascular rehabilitation].

    PubMed

    Mathe, Nathalie; Lascoux, Léa; Puchault, Hélène

    2014-01-01

    A pedagogical tool as well as a concept, situated learning describes the skills used in a situation in a given context, structuring the reflection, analysis and choice of nursing procedures, based on theoretical knowledge, know-how and interpersonal skills. A vascular rehabilitation team has chosen to formalise two situations from among the most common care procedures carried out in the department: the changing of complex dressings and ensuring the personal hygiene and comfort of a dependent patient with skin wounds.

  19. Setting Up a Preventive Maintenance Program.

    ERIC Educational Resources Information Center

    Dwyer, Michael J., Jr.

    1980-01-01

    The steps of a preventive maintenance program are to determine what equipment will fall within the program; to determine what tasks are necessary to perform the required maintenance, and the frequency of each task; and to build a workable schedule. (Author/MLF)

  20. NSF Sets Up Regional Instrument Centers.

    ERIC Educational Resources Information Center

    Rawls, Rebecca L.

    1979-01-01

    Explains the aims behind the first six regional facilities that are being established at universities that already have strong state-of-the art programs in the areas of their grants. Gives a brief look at the facilities and what each has to offer. (GA)

  1. Setting Up a Small School: Information Pack.

    ERIC Educational Resources Information Center

    Carnie, Fiona

    A growing number of families are looking for alternative ways to educate their children, as discontent with mainstream schooling rises. Human Scale Education sees the problem with the education system in the United Kingdom as one of size and believes that most schools and classes are too large for children to be known individually by their…

  2. NEP advocates urged: set up needle exchange.

    PubMed

    1995-12-01

    The Point Defiance AIDS Projects, founded in 1988, is a successful needle exchange program (NEP) in Tacoma, WA. Program director David Purchase's approach to potential community resistance is based on the theory that it is better to seek forgiveness than to beg permission. Since its inception, the program has faced two legal battles that have been resolved in favor of Point Defiance. The Washington State Supreme Court ruled that exchange programs should be exempted from state paraphernalia laws. Point Defiance employs three full-time staff members experienced with the drug-using community to conduct on-site exchanges. HIV seroprevalence among injection drug users has remained below five percent over the last five years. PMID:11362933

  3. Setting up Uncertified Teachers to Succeed

    ERIC Educational Resources Information Center

    Sterling, Donna R.; Frazier, Wendy M.

    2011-01-01

    A study of new teachers with science degrees but little or no training in education found that coaches who spent time in their classrooms provided the most effective support for new teachers. Science methods courses provided by a university also were very helpful for the new teacher. But academic mentors for science content and teacher mentors who…

  4. Setting up Conditions for Negotiation in Science

    ERIC Educational Resources Information Center

    Yoon, Sae Yeol; Bennett, William; Mendez, Claudia Aguirre; Hand, Brian

    2010-01-01

    When using an argument based inquiry approach like the Science Writing Heuristic (SWH) approach, argumentation between peers and with a teacher will provide great opportunities for students to experience negotiation of meaning in relation to science content. However, students do not automatically engage in dialogue and argumentation with…

  5. Setting up a crisis recovery plan.

    PubMed

    Phelps, N L

    1986-01-01

    When companies, institutions, or for that matter even nations suddenly find themselves face to face with a disaster, more often than not the necessary forces can be quickly marshaled to deal with the matter at hand. However, when the dust begins to settle, the after shocks are often more devastating and costly to the organization over the long term than the original crisis. That is why crisis recovery planning should be a part of any strategic planning process.

  6. Japan sets up program for biological research

    SciTech Connect

    Lepkowski, W.

    1988-05-16

    Japanese officials have put final touches on plans for a global biological research program, called the Human Frontier Science Program, that they hope will launch their country into a new era of international science. Japan will establish a nongovernmental secretariat for the program and will manage it through an international governing council. Almost all the funding in the countries involved- Japan, the U.S., Canada, and the European Community countries- will be provided by Japan, at least at first. In its present design, the program consists of two thrusts- one in the neurosciences with emphasis on brain function, the other on the chemistry and molecular biology of gene expression. The program in the first year would consist of 30 to 50 direct research grants to researchers working in teams, 100 to 200 postdoctoral fellowships, and 10 to 20 workshops. Young researchers would be favored for funding. The average annual grant size would total $500,000, and postdoctoral awards would average $50,000.

  7. Setting up a Death Row Psychiatry Program.

    PubMed

    Yanofski, Jason

    2011-02-01

    Death row psychiatry contains a complex set of clinical, ethical, and legal questions. This Forensic Files column makes a case for correctional institutions starting death row programs to address these issues through uniform policies. A list of the relevant issues is provided. Specific issues discussed include death row psychiatric assessment, considering "justifiable" depression, treating for competency to be executed, and balancing boundaries between clinical and forensic work.

  8. Setting up a clinical engineering department.

    PubMed

    Guignon, E

    1980-01-01

    The problems of cost, personnel qualifications, task assignment, and productivity involved in establishing a clinical engineering department are addressed in this paper. A basic department consisting of a Clinical Engineer, a Biomedical Equipment Technician, a Testing Technician and a Clerical Assistant can provide a full range of clinical engineering services to a hospital with 225 instruments. The annual cost of such a department, including materials, would be approximately $90,000. The average capital investment in a selection of 225 instruments would be on the order of $860,000. This paper discusses levels of skills within a clinical engineering department, and the services that a hospital could expect from a four-man department. PMID:10246340

  9. Setting up a life course questionnaire.

    PubMed

    Sampogna, Francesca

    2013-01-01

    In order to give a practical meaning to a concept, it is necessary to measure it. In this chapter, some guidelines for the creation of a life course questionnaire are given, starting from the concept of measurement and all the properties (validity, reliability, responsiveness and interpretability) that an instrument must have, to be defined as a measurement tool. The first step is to define the construct to be measured. Cumulative life course impairment (CLCI) assumes impairment over time of the life course of individuals; key concepts of CLCI are accumulation of risk as well as timing of risk exposure. CLCI is a longitudinal construct, and in order to measure it, it is imperative to take the role of time into account. Questionnaires administered at a certain moment during the patient's life will investigate the impact the disease had on his/her life from the beginning until that moment. Items to be assessed in patients suffering from chronic condition will be, among others, physical and psychological comorbidities, feelings of stigmatization and coping style. Together with the given personality, and other personal and clinical characteristics, they may contribute to changes in the life trajectory compared to a hypothetical 'unaffected average life course'. At the end of the chapter, an example of life course questionnaire is proposed.

  10. Setting up a Death Row Psychiatry Program.

    PubMed

    Yanofski, Jason

    2011-02-01

    Death row psychiatry contains a complex set of clinical, ethical, and legal questions. This Forensic Files column makes a case for correctional institutions starting death row programs to address these issues through uniform policies. A list of the relevant issues is provided. Specific issues discussed include death row psychiatric assessment, considering "justifiable" depression, treating for competency to be executed, and balancing boundaries between clinical and forensic work. PMID:21468293

  11. Setting up an HIV screening program.

    PubMed

    Williams, A; Dodd, R Y

    1989-01-01

    Human immunodeficiency virus-1 (HIV-1) screening programs currently are based primarily on the detection of specific HIV-1 antibodies by the commercially available enzyme immunoassay (EIA) combined with highly specific confirmation procedures. Factors to be considered in establishing a screening program include test performance characteristics, economy, confidentiality and notification procedures, legal and regulatory issues, proficiency and quality control measures, and laboratory safety. Commercial EIA screening in conjunction with a licensed Western blot assay permits the classification of all but a few serum samples into HIV-1-positive and HIV-1-negative categories. The occasional indeterminate results often can be resolved by following a defined retesting/resampling algorithm or by using research-level test procedures that may become available for diagnostic use in the future. Although screening of patient populations with an increased risk of HIV-1 exposure will improve the predictive accuracy of an initial screening assay, confirmation testing should nonetheless be performed for all EIA reactive sera regardless of the source. Local HIV-1 screening programs that meet minimum-volume requirements can result in considerable savings and flexibility for a moderate-size institution. However, before this type of program is undertaken, numerous technical and ethical considerations need to be addressed.

  12. Setting up a CFO Trust Fund

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2011-01-01

    Understanding the importance of a solid relationship with the head of finance is critical to success, both for the IT department and the institution as a whole. Never has this been truer than in today's bleak economy, as CFOs become increasingly cautious about initiatives that involve significant expense, yet information technology can help…

  13. Assessment of three-dimensional set-up errors using megavoltage computed tomography (MVCT) during image-guided intensity-modulated radiation therapy (IMRT) for craniospinal irradiation (CSI) on helical tomotherapy (HT).

    PubMed

    Gupta, Tejpal; Upasani, Maheshkumar; Master, Zubin; Patil, Anita; Phurailatpam, Reena; Nojin, Siji; Kannan, Sadhana; Godasastri, Jayant; Jalali, Rakesh

    2015-02-01

    The purpose of this study was to assess three-dimensional (3D) set-up errors using megavoltage computed tomography (MVCT) during image-guided intensity-modulated radiation therapy (IMRT) for supine craniospinal irradiation (CSI) on helical tomotherapy (HT). Patients were immobilized in a customized 4-clamp thermoplastic head mask with or without whole-body vacuum cradle. Set-up was based primarily on a set of cranial fiducial markers. MVCT scans were acquired and co-registered with planning scan separately at three different levels (brain, upper, and lower spine) at every fraction. Only translational displacements were analysed, wherein positive sign denotes deviation in anterior, left, and superior direction; while negative sign denotes deviation in posterior, right, and inferior direction. Mean displacements, systematic, and random errors of the study population were calculated at all three levels separately. Local residual uncertainty of the upper and lower spine was also derived assuming perfect co-registration of the skull. Set-up margins for clinical target volume (CTV) to planning target volume (PTV) were derived at these three levels separately using published margin recipes. Data from 1868 co-registrations in 674 fractions on 33 patients was included. The mean displacements in the lateral, longitudinal, and vertical directions were -1.21, -1.36, and 1.38 mm; -1.25, -0.34, and 0.65 mm; and -1.47, -2.78, and 0.22 mm for the brain; upper spine; and lumbar spine respectively. The corresponding 3D vector of displacement was 2.28; 1.45; and 3.15 mm respectively. There was a distinct systematic trend towards increasing inaccuracy from the brain towards the lower spine. Using Stroom's formula, the minimum recommended CTV to PTV margins in absence of daily image-guidance were 6.5; 7.0; and 9.5 mm for the brain; upper spine; and lower spine respectively. This increased to 7.5; 8.5; and 11.5 mm using van Herk's formula. Subset and sensitivity analyses

  14. Reliable set-up for in-loop ¹¹C-carboxylations using Grignard reactions for the preparation of [carbonyl-¹¹C]WAY-100635 and [¹¹C]-(+)-PHNO.

    PubMed

    Rami-Mark, Christina; Ungersboeck, Johanna; Haeusler, Daniela; Nics, Lukas; Philippe, Cecile; Mitterhauser, Markus; Willeit, Matthaeus; Lanzenberger, Rupert; Karanikas, Georgios; Wadsak, Wolfgang

    2013-12-01

    Aim of this work was the implementation of a generalized in-loop synthesis for (11)C-carboxylations and subsequent (11)C-acylations on the TRACERlab FxC Pro platform. The set-up was tested using [carbonyl-(11)C]WAY-100635 and, for the first time, [(11)C]-(+)-PHNO. Its general applicability could be demonstrated and both [carbonyl-(11)C]WAY-100635 and [(11)C]-(+)-PHNO were prepared with high reliability and satisfying outcome. PMID:23974301

  15. A multiprocessor coupled ice-ocean model for the Baltic Sea: Application to salt inflow

    NASA Astrophysics Data System (ADS)

    Meier, H. E. Markus; DöScher, Ralf; FaxéN, Torgny

    2003-08-01

    Within the Swedish Regional Climate Modeling Program, SWECLIM, a three-dimensional (3-D) coupled ice-ocean model for the Baltic Sea has been developed to simulate physical processes on timescales of hours to decades. The code has been developed based on the massively parallel version of the Ocean Circulation Climate Advanced Modeling (OCCAM) project of the Bryan-Cox-Semtner model. An elastic-viscous-plastic ice rheology is employed, resulting in a fully explicit numerical scheme that improves computational efficiency. An improved two-equation turbulence model has been embedded to simulate the seasonal cycle of surface mixed layer depths as well as deepwater mixing on decadal timescale. The model has open boundaries in the northern Kattegat and is forced with realistic atmospheric fields and river runoff. Optimized computational performance and advanced algorithms to calculate processor maps make the code fast and suitable for multi-year, high-resolution simulations. As test cases, the major salt water inflow event in January 1993 and the stagnation period 1980-1992, have been selected. The agreement between model results and observations is regarded as good. Especially, the time evolution of the halocline in the Baltic proper is realistically simulated also for the longer period without flux correction, data assimilation, or reinitialization. However, in particular, smaller salt water inflows into the Bornholm Basin are underestimated, independent of the horizontal model resolution used. It is suggested that the mixing parameterization still needs improvements. In addition, a series of process studies of the inflow period 1992/1993 have been performed to show the impact of river runoff, wind speed, and sea level in Kattegat. Natural interannual runoff variations control salt water inflows into the Bornholm Basin effectively. The effect of wind speed variation on the salt water flux from the Arkona Basin to the Bornholm Basin is minor.

  16. Further considerations for the setting up of a low background whole-body counter for internal dosimetry at Waste Isolation Pilot Plant (WIPP) Carlsbad, NM, USA: transmitted photon component.

    PubMed

    Pillalamarri, Ila; Jagam, P

    2015-04-01

    One of the further considerations in the present work, while setting up a low background whole-body counter (WBC) underground at the Waste Isolation Pilot Plant (WIPP) is to reduce the background in the energy region of interest <100 keV. The goal of the present work is to determine the adequacy of a chamber located underground at WIPP of dimensions 1.83 m × 1.22 m at the base, 1.83 m high, with 15 cm thick pre-world-war II steel shielding. The objective of the present work is to estimate the transmitted photon flux into this chamber for setting up the low background WBC. The transmitted photon flux is simulated with the GEANT code for an incident photon flux consisting only of 1461 keV photons. The results are discussed with respect to a detector of choice for detecting <50 mBq emitting photons in the energy region <100 keV.

  17. Spawning areas of eastern Baltic cod revisited: Using hydrodynamic modelling to reveal spawning habitat suitability, egg survival probability, and connectivity patterns

    NASA Astrophysics Data System (ADS)

    Hinrichsen, H.-H.; Lehmann, A.; Petereit, C.; Nissling, A.; Ustups, D.; Bergström, U.; Hüssy, K.

    2016-04-01

    In the highly variable environment of the Baltic Sea two genetically distinct cod stocks exist, one west of the island of Bornholm, which is referred to as the western stock, and one to the east of Bornholm, the eastern stock. A hydrodynamic model combined with a Lagrangian particle tracking technique was utilised to provide spatially and temporally resolved long-term information on environmentally-related (i) spawning habitat size, (ii) egg/yolk-sac larval survival, (iii) separation of causes of mortality, and (iv) connectivity between spawning areas of eastern Baltic cod. Simulations were performed to quantify processes generating heterogeneity in spatial distribution of cod eggs and yolk sac larvae up to the first-feeding stage. The spatial extent of cod eggs represented as virtual drifters is primarily determined by oxygen and salinity conditions at spawning, which define the habitat requirement to which cod's physiology is suited for egg development. The highest habitat suitability occurred in the Bornholm Basin, followed by the Gdansk Deep, while relatively low habitat suitability was obtained for the Arkona and the Gotland Basin. During drift egg and yolk sac larval survival is to a large extent affected by sedimentation. Eggs initially released in the western spawning grounds (Arkona and Bornholm Basin) were more affected by sedimentation than those released in the eastern spawning grounds (Gdansk Deep and Gotland Basin). Highest relative survival of eastern Baltic cod eggs occurred in the Bornholm Basin, with a pronounced decrease towards the Gdansk Deep and the Gotland Basin. Relatively low survival rates in the Gdansk Deep and in the Gotland Basin were attributable to oxygen-dependent mortality. Low oxygen content had almost no impact on survival in the Arkona Basin. For all spawning areas temperature dependent mortality was only evident after severe winters. Egg buoyancy in relation to topographic features like bottom sills and strong bottom slopes

  18. Community and connectivity: summary of a community based monitoring program set up to assess the movement of nutrients and sediments into the Great Barrier Reef during high flow events.

    PubMed

    Devlin, M; Waterhouse, J; Brodie, J

    2001-01-01

    The Great Barrier Reef (GBR) system encompasses the largest system of corals and related life forms anywhere in the world. The health of this extensive system, particularly the inshore area, is dependent on the relationship between the GBR and adjacent coastal catchments. The major impact of agricultural practices on the GBR is the degradation of water quality in receiving (rivers) waters, caused by increased inputs of nutrients, suspended sediments and other pollutants. For the past three years, the Great Barrier Reef Marine Park Authority (GBRMPA) has been involved with the co-ordination of a river-monitoring program, specifically targeting the sampling of rivers during flood events. Representative sites were set up along two North Queensland rivers, the Russell-Mulgrave and Barron Rivers. This monitoring program is run in conjunction with the Queensland Department of Natural Resources' Waterwatch program. The program involves intensive sampling of first flush, extreme flow and post flood conditions over the two rivers. Extreme flow conditions are sampled over a limited time span (48 hours) with trained volunteers at 4-hour intervals. Concentrations measured in the flood events are dependent on land use characteristic, and extent of flow. Concentrations of dissolved and particulate nutrients are higher if the extreme flow event is part of the first flush cycle. Concentrations of DIN and DIP measured before, during and after a major flood event suggest that there is a large storage of inorganic material within the Barron and Russell-Mulgrave agricultural subcatchments that move over a period of days, and perhaps weeks. This program created a forum in which GBRMPA liased with the Barron and Russell-Mulgrave community about the connectivity existing between the river and the Great Barrier Reef lagoon.

  19. A new set-up for simultaneous high-precision measurements of CO2, δ13C-CO2 and δ18O-CO2 on small ice core samples

    NASA Astrophysics Data System (ADS)

    Jenk, Theo Manuel; Rubino, Mauro; Etheridge, David; Ciobanu, Viorela Gabriela; Blunier, Thomas

    2016-08-01

    Palaeoatmospheric records of carbon dioxide and its stable carbon isotope composition (δ13C) obtained from polar ice cores provide important constraints on the natural variability of the carbon cycle. However, the measurements are both analytically challenging and time-consuming; thus only data exist from a limited number of sampling sites and time periods. Additional analytical resources with high analytical precision and throughput are thus desirable to extend the existing datasets. Moreover, consistent measurements derived by independent laboratories and a variety of analytical systems help to further increase confidence in the global CO2 palaeo-reconstructions. Here, we describe our new set-up for simultaneous measurements of atmospheric CO2 mixing ratios and atmospheric δ13C and δ18O-CO2 in air extracted from ice core samples. The centrepiece of the system is a newly designed needle cracker for the mechanical release of air entrapped in ice core samples of 8-13 g operated at -45 °C. The small sample size allows for high resolution and replicate sampling schemes. In our method, CO2 is cryogenically and chromatographically separated from the bulk air and its isotopic composition subsequently determined by continuous flow isotope ratio mass spectrometry (IRMS). In combination with thermal conductivity measurement of the bulk air, the CO2 mixing ratio is calculated. The analytical precision determined from standard air sample measurements over ice is ±1.9 ppm for CO2 and ±0.09 ‰ for δ13C. In a laboratory intercomparison study with CSIRO (Aspendale, Australia), good agreement between CO2 and δ13C results is found for Law Dome ice core samples. Replicate analysis of these samples resulted in a pooled standard deviation of 2.0 ppm for CO2 and 0.11 ‰ for δ13C. These numbers are good, though they are rather conservative estimates of the overall analytical precision achieved for single ice sample measurements. Facilitated by the small sample requirement

  20. Set-up of a multivariate approach based on serum biomarkers as an alternative strategy for the screening evaluation of the potential abuse of growth promoters in veal calves

    PubMed Central

    Pirro, Valentina; Girolami, Flavia; Spalenza, Veronica; Gardini, Giulia; Badino, Paola; Nebbia, Carlo

    2015-01-01

    A chemometric class modelling strategy (unequal dispersed classes – UNEQ) was applied for the first time as a possible screening method to monitor the abuse of growth promoters in veal calves. Five serum biomarkers, known to reflect the exposure to classes of compounds illegally used as growth promoters, were determined from 50 untreated animals in order to design a model of controls, representing veal calves reared under good, safe and highly standardised breeding conditions. The class modelling was applied to 421 commercially bred veal calves to separate them into ‘compliant’ and ‘non-compliant’ with respect to the modelled controls. Part of the non-compliant animals underwent further histological and chemical examinations to confirm the presence of either alterations in target tissues or traces of illegal substances commonly administered for growth-promoting purposes. Overall, the congruence between the histological or chemical methods and the UNEQ non-compliant outcomes was approximately 58%, likely underestimated due to the blindness nature of this examination. Further research is needed to confirm the validity of the UNEQ model in terms of sensitivity in recognising untreated animals as compliant to the controls, and specificity in revealing deviations from ideal breeding conditions, for example due to the abuse of growth promoters. PMID:25730172

  1. Emerging organisms in a tertiary healthcare set up

    PubMed Central

    Khan, Inam Danish; Sahni, Ajay Kumar; Bharadwaj, Reena; Lall, Mahima; Jindal, A.K.; Sashindran, V.K.

    2013-01-01

    Background One-tenth of all infectious diseases are attributable to emerging organisms. As emerging organisms sporadically affect a relatively small percentage of population they are not studied at large. This study was aimed at studying the characteristics of emerging organisms encountered from various clinical samples in an apex tertiary care multispeciality teaching and research hospital. Methods 16,918 positive isolates obtained from 66,323 culture samples processed in the clinical microbiology lab of an apex multispeciality hospital during 2011–2012 were included after a pilot study. Both manual and automated systems were used for identification and antimicrobial susceptibility. The frequency of isolation, sources, referring centers, resistance and susceptibility profiles, phenotypic characteristics and number of reports in PubMed were studied. Results Out of 16,918 isolates, 13,498 (79.78%) were Gram negative bacteria, 3254 (19.23%) were Gram positive bacteria and 166 (0.98%) were yeasts. A total of 483 (2.85%, 95% CI 2.6%–3.1%) emerging organisms including 116 (0.69%, 95% CI 0.57%–0.81%) emerging species were identified comprising 54 genera. Conclusion Emerging organisms are likely to evade routine identification or be disregarded as non-contributory. Astute efforts directed at identification of emerging isolates, decisions by clinical microbiologists and treating physicians and containment of infection are required. PMID:24843199

  2. Setting up an in-office independent medical examination company.

    PubMed

    Hamilton, Martha

    2002-04-01

    In a time of declining reimbursement for patient care services, establishing an in-office IME company enables orthopedic practices to generate additional revenue to subsidize clinical activities without compromising the credibility and integrity of their physicians; however, the decision to enter the medical/legal consultation business should be considered carefully. A thorough analysis of the industry, applicable laws, costs-versus-benefits, and the local marketplace is critical in helping the practice to evaluate the feasibility of establishing the new business and develop a product that is well differentiated. The practice should approach the day-to-day management of the IME company with the same careful attention that it pays to the management of its orthopedic service. This includes creating a staffing and information technology infrastructure that supports the new business and allows for its growth. An attitude of continuous learning whereby the physician-reviewer seeks out information about the customer's needs and market shifts enables the practice to respond swiftly to these needs and shifts and further position itself as an innovative provider of medical/legal services.

  3. The Setting Up of a Resources Centre. 3: Retrieval Systems.

    ERIC Educational Resources Information Center

    Malcolm, Adam H., Ed.

    Assembled to aid educators and administrators in Scotland in selecting and applying appropriate information retrieval systems in learning resources centers, this collection contains an introductory essay and four articles on the characteristics and features of some basic information retrieval systems. The articles include (1) a discussion of the…

  4. SETTING UP A LABORATORY AB INITIO IN A REMOTE LOCATION

    EPA Science Inventory

    For many years the USEPA's National Risk Management Research Laboratory in Cincinnati, OH has operated a pilot plant approximately 5 kilometers from its main research facility. Originally, this Tet and Evaluation (T&E) facility was sited to be adjacent to the City of Cincinnati's...

  5. Setting up a breast cancer family history clinic.

    PubMed Central

    Saunders, C.; Vijay, V.; Stein, J.; Baum, M.

    1999-01-01

    Breast cancer causes around 21,000 deaths per year in the UK, the vast majority of these occurring in women aged over 50 years with no genetic predisposition to the disease. Screening and symptomatic services for these women, although by no means perfect or homogeneous, have gradually improved over the last 10 years and, perhaps as a result of this, together with increased use of adjuvant systemic therapy, mortality in this group has fallen. Despite this reassuring state of affairs, media interest in the disease and patients' perception of their risk of developing breast cancer have risen. Part of this is undoubtedly due to the new scientific developments in cancer genetics and, in particular, identification of the BRCA1 gene in 1994 and BRCA2 gene shortly afterwards. These genes are dominantly inherited with up to 80% penetrance; thus, women (and occasionally men) inherit these genes and have a high lifetime risk of developing breast cancer, usually at a younger age than average and possibly of a more aggressive phenotype. Unaffected family members can now be screened and, if they prove carriers, screening for early detection and prevention strategies such as bilateral prophylactic mastectomy can be offered. Because of the high risk of ovarian cancer in BRCA1 carriers, screening or prophylactic ovariectomy may also be considered. PMID:10655892

  6. The Setting Up of a Resources Centre. 1: Basic Ideas.

    ERIC Educational Resources Information Center

    Malcolm, Adam H.

    This guidebook reviews the basic educational role of learning resources centers in elementary-secondary education, and outlines the facility requirements, material requirements, and functions of a basic resources center. The educational issues surrounding the development of resources centers are briefly addressed, including resource-based…

  7. Setting-up tension in the style of Marantaceae.

    PubMed

    Pischtschan, E; Classen-Bockhoff, R

    2008-07-01

    The Marantaceae stand out from other plant families through their unique style movement which is combined with a highly derived form of secondary pollen presentation. Although known for a long time, the mechanism underlying the movement is not yet understood. In this paper, we report an investigation into the biomechanical principles of this movement. For the first time we experimentally confirm that, in Maranta noctiflora, longitudinal growth of the maturing style within the 'straitjacket' of the hooded staminode involves both arresting of the style before tripping and building up of potential for the movement. The longer the style grows in relation to the enclosing hooded staminode, the more does its capacity for curling increase. We distinguish between the basic tension that a growing style builds up normally, even when the hooded staminode is removed beforehand, and the induced tension which comes about only under the pressure of a too short hooded staminode and which enables the movement. The results of our investigations are discussed in relation to previous interpretations, ranging from biomechanical to electrophysiological mechanisms. PMID:18557904

  8. Setting Up a Preventive Maintenance Program: Part 2.

    ERIC Educational Resources Information Center

    Dwyer, Michael J., Jr.

    1980-01-01

    Outlines how a good preventive maintenance program can be scheduled and followed up to insure that the inspections have been performed. Both manually operated and computerized preventive maintenance programs are discussed. (MLF)

  9. SETTING UP FARM RECORDS TO PROVIDE FOR ANALYSIS.

    ERIC Educational Resources Information Center

    Illinois Univ., Urbana. Coll. of Agriculture.

    RESOURCE MATERIAL ON FARM RECORD ANALYSIS FOR USE IN HIGH SCHOOL VOCATIONAL AGRICULTURE AND ADULT FARMER CLASSES WAS DESIGNED BY SUBJECT MATTER SPECIALISTS, TEACHER EDUCATORS, SUPERVISORS, AND TEACHERS TO PROVIDE TEXTUAL MATERIAL FOR STUDENTS ON THE PURPOSES OF RECORDS, ANALYSIS MEASURES, INVENTORIES, DEPRECIATION SCHEDULES, FINANCIAL TRANSACTION…

  10. It's COWANBUNGA Time: Setting up Shop in a Foreign Country

    ERIC Educational Resources Information Center

    McKay, Ruth B.; Chung, Ed

    2008-01-01

    What happens to business negotiations when culture gets in the way? Participants are about to find out. This game is an international negotiation simulation for the classroom. Participants learn, through role-playing and observation, how cross-cultural differences complicate international business negotiations. Students are formed into pairs of…

  11. Setting Up an Exchange Operation in the Small Special Library.

    ERIC Educational Resources Information Center

    Carter, Harriet H.

    1978-01-01

    Describes the planning process and the procedures established to get the Fels Research Institute Library started in exchange activities through the ALA Duplicates Exchange Union and the MLA Exchange. Methods for evaluating the success of these programs after one year are explained. (Author/MBR)

  12. Setting-up tension in the style of Marantaceae.

    PubMed

    Pischtschan, E; Classen-Bockhoff, R

    2008-07-01

    The Marantaceae stand out from other plant families through their unique style movement which is combined with a highly derived form of secondary pollen presentation. Although known for a long time, the mechanism underlying the movement is not yet understood. In this paper, we report an investigation into the biomechanical principles of this movement. For the first time we experimentally confirm that, in Maranta noctiflora, longitudinal growth of the maturing style within the 'straitjacket' of the hooded staminode involves both arresting of the style before tripping and building up of potential for the movement. The longer the style grows in relation to the enclosing hooded staminode, the more does its capacity for curling increase. We distinguish between the basic tension that a growing style builds up normally, even when the hooded staminode is removed beforehand, and the induced tension which comes about only under the pressure of a too short hooded staminode and which enables the movement. The results of our investigations are discussed in relation to previous interpretations, ranging from biomechanical to electrophysiological mechanisms.

  13. Urodynamic testing: physiological background, setting-up, calibration and artefacts.

    PubMed

    Raz, Orit; Tse, Vincent; Chan, Lewis

    2014-11-01

    Urodynamics (UDS) is an interactive diagnostic study of lower urinary tract function. It is composed of several tests that can be used to obtain functional information about urine storage and expulsion. Its main goal is to reproduce the patients' symptoms and determine their cause. The present article is a review of the physiological concepts behind UDS, and explains the various normal and abnormal forces and parameters that are measured and used during the tests to assist the physician in making a diagnosis. It outlines the importance and methods of the calibration of UDS equipment to optimise diagnostic accuracy and reliability, which would have a crucial impact over the treatment's decision, and consequently the patient's outcome.

  14. [Setting up supportive care in oncology: reflexions and suggestions.].

    PubMed

    Colombat, P; Antoun, S; Aubry, R; Banterla-Dadon, I; Barruel, F; Bonel, J-M; Bonnin, J-C; Chassignol, L; Chollet, A; Chvetzoff, G; D'Hérouville, D; Drouart, M; Gaillet, H; Ganem, G; Krakowski, I; Morigault, M-O; Nallet, G; Rolland, J; Suc, A

    2009-09-01

    A group of 19 health professionals implicated in supportive care wanted to suggest some reflexions for organization, setting and evaluation of the supportive care in institutions and health territories. The suggested organization must be applicable to any cancer patient and the place of the care whatever the age, the stage of the disease; in the future, must be applicable to any patient with serious chronic illness. This organization must allow to optimize the accompaniment and the care of the patients and their close relations by 1) precise and regular analysis of their needs; 2) the respect of the continuity of the health care; 3) the setting of collaborative practice and transversality in the care. It is not a new medical speciality but a coordination of competences for patients and their families. PMID:19903599

  15. Engelhard and IFP/Procatalyse set up worldwide catalysts venture

    SciTech Connect

    Hunter, D.

    1992-12-02

    The new joint venture between Engelhard (Iselin, N) and Procatalyse (Paris), jointly owned by process licenser Institut Francais de Petrole (IFP; Rueil Malmaison, France) and Rhone-Poulenc (RP; Paris), marks the latest episode in the worldwide catalyst industry's restructuring. The operation will combine Engelhard's catalyst line, apart from its fluid catalytic cracking (FCC) and emission catalysts, with Procatalyse's offering. To be launched at the beginning of 1993, the venture will have annual sales of about $75 million. Reforming catalysts will be the biggest part of the venture's lineup at the outset, making it number three in the US, behind UOP - which dominates the sector - and Criterion. IFP is starting to establish a presence in North America with its reforming technology. But flat gasoline demand and reductions on aromatics in gasoline limit requirements for new reforming units, comments one competitor. Although lower sulfur specifications are putting some new demand into the hydrodesulfurization (HDS) catalyst market, both partners play down their prospects. The sector, whose leaders are Akzo and Crtierion, is continuing to suffer from severe overcapacity. Procatalyse's HDS business is mainly linked to IFP licensees, while Engelhard is due to mothball its Salt Lake City HDS catalyst plant by year-end, transferring output to Elyria.

  16. Setting Up Computer Workstations in Classrooms and Libraries.

    ERIC Educational Resources Information Center

    Anderson, Glenn

    1996-01-01

    Explains the benefits of computer workstations in schools and describes various components, including projection tools such as LCD (liquid crystal display) projectors, printers, Internet connections, tape drives, digitizers, scanners, laserdisc players, and CD-i (interactive) players. (LRW)

  17. The Setting Up of a Resources Centre. 2: Planning & Staffing.

    ERIC Educational Resources Information Center

    Tucker, Richard N.

    Produced for use by educators and administrators in Scotland involved in planning and developing learning resources centers in elementary and secondary schools, this guide contains: (1) examples and discussion of the allocation of space for resources centers in schools with different architectural layouts, (2) three case studies of schools which…

  18. Prerequisites for Setting Up Management System in Municipal Retail Trade

    ERIC Educational Resources Information Center

    Suraeva, Maria O.; Grigoryants, Igor A.; Karpova, Galina A.; Khoreva, Lyubov V.; Schreyer, Alexander V.; Sirotkin, Victor A.

    2016-01-01

    The relevance of the research problem Urban district, management, trade, sales network is determined by the number of complex problems that exist in present Samara municipal retail trade system, which is manifested in the lack of regulation, a glut of sales area, and poorly developed infrastructure. The purpose of this article is to form a…

  19. Justifying Differential Derivations when Setting Up Definite Integrals

    ERIC Educational Resources Information Center

    Tarvainen, K.

    2008-01-01

    This paper addresses the forming of integral expressions such as [integral][superscript b][subscript a]f(x)dx by differential or infinitesimal derivations. A rigorous justification of these handy informal derivations is a major pedagogical problem in calculus. In this paper, checks are presented by which one can usually verify--with clear…

  20. Modeling Steady-State Groundwater Flow Using Microcomputer Spreadsheets.

    ERIC Educational Resources Information Center

    Ousey, John Russell, Jr.

    1986-01-01

    Describes how microcomputer spreadsheets are easily adapted for use in groundwater modeling. Presents spreadsheet set-ups and the results of five groundwater models. Suggests that this approach can provide a basis for demonstrations, laboratory exercises, and student projects. (ML)

  1. Towards bridging biogeochemical and fish-production models

    NASA Astrophysics Data System (ADS)

    Fennel, Wolfgang

    The paper presents a theoretical approach to formulate a model which comprises the full food web. The lower part of the food web is represented by a biogeochemical model which interacts explicitly with a fish-production model. The fish-production model component builds on existing theories but was substantially reformulated in order to facilitate the model coupling. The dynamics of the fish-production model is basically driven by the predator-prey interaction. We use the example of the Baltic Sea, which has a relatively simple foodweb structure. The fish biomass is dominated by three groups, sprat, herring and cod, which represent about 80% of fish biomass in the Baltic. The zooplanktivors sprat and herring are eaten by cod. In this paper we start the construction of the model as a simple box system, which can be considered as an isolated water column of 10 × 10 km 2 times the water depth in the central Bornholm basin of the Baltic Sea. The stepwise building up of the model is illustrated by example simulations, which allow to assess the consistence of the theoretical approach and the choices of parameters. As last step we introduce a simple biogeochemical model and link it with the fish model. The resulting model system is strictly mass conserving without unspecified sources of food or so. We conduct experiments with the model system and show that it can reproduce features such as interannual variation in fish catches and trophic cascades.

  2. Random Models in the Classroom 1: An Example

    ERIC Educational Resources Information Center

    Selkirk, Keith

    1973-01-01

    A mathematical model of a soccer-league competition results is set up and investigated using simple randomization techniques. The hypothesis that winning the league championship was purely luck was statistically tested. (JP)

  3. Take the Reins on Model Quality with ModelCHECK and Gatekeeper

    NASA Technical Reports Server (NTRS)

    Jones, Corey

    2012-01-01

    Model quality and consistency has been an issue for us due to the diverse experience level and imaginative modeling techniques of our users. Fortunately, setting up ModelCHECK and Gatekeeper to enforce our best practices has helped greatly, but it wasn't easy. There were many challenges associated with setting up ModelCHECK and Gatekeeper including: limited documentation, restrictions within ModelCHECK, and resistance from end users. However, we consider ours a success story. In this presentation we will describe how we overcame these obstacles and present some of the details of how we configured them to work for us.

  4. Advanced flight design systems subsystem performance models. Sample model: Environmental analysis routine library

    NASA Technical Reports Server (NTRS)

    Parker, K. C.; Torian, J. G.

    1980-01-01

    A sample environmental control and life support model performance analysis using the environmental analysis routines library is presented. An example of a complete model set up and execution is provided. The particular model was synthesized to utilize all of the component performance routines and most of the program options.

  5. Microtron Modelling and Control

    SciTech Connect

    Krist, Pavel; Bila, Jiri

    2010-01-05

    The article describes the design of the mathematical model and automatic control system of the microtron (high frequency cyclic electron accelerator). This type of accelerator was controlled manually till now. The critical values have been set up empirically on the basis of the previous operational experiences. The designed automatic control system with fuzzy controller should increase the accelerated electrons current value and improve the beam stability.

  6. Unstructured-grid model for the North Sea and Baltic Sea: Validation against observations

    NASA Astrophysics Data System (ADS)

    Zhang, Yinglong J.; Stanev, E. V.; Grashorn, S.

    2016-01-01

    A new unstructured-grid model and its application to the North Sea and Baltic Sea are described. The research focus is on the dynamics in the two basins and in the multiple straits connecting them and more specifically on how the model replicates the temporal and spatial variability of physical processes. The comparison against observed data indicates the realism in the simulations of the exchange flows. The simulations demonstrated that in contrast to the tidal variability which decreases in the strait, the role of the barotropic forcing due to weather systems increases. In this zone reversal of transport is well manifested by the increased difference between the surface and bottom salinity values. Small sub-basins like Arkona and Bornholm play the role of reservoirs for denser water which under specific conditions cascades on its way to the Gotland Deep. Unlike the intermediate and deep water salinity in the Baltic Sea, which is strongly affected by fluxes in the straits, the simulated winter-refill and evolution of cold intermediate water are rather driven by surface cooling and processes in the upper mixed layer.

  7. Using Multilevel Modeling in Counseling Research

    ERIC Educational Resources Information Center

    Lynch, Martin F.

    2012-01-01

    This conceptual and practical overview of multilevel modeling (MLM) for researchers in counseling and development provides guidelines on setting up SPSS to perform MLM and an example of how to present the findings. It also provides a discussion on how counseling and developmental researchers can use MLM to address their own research questions.…

  8. Model of Adult Career Education in Corrections.

    ERIC Educational Resources Information Center

    Ryan, T. A.; And Others

    The model was designed to provide a guide for systematic planning, implementation, and evaluation of adult career education in correctional settings, utilizing a systems approach. It consists of seven chapters and a flowchart presenting seven major functions which must be carried out: (1) establishing a conceptual framework, (2) setting up an…

  9. Institutionalizing Innovation in an Organization: A Model and Case Study.

    ERIC Educational Resources Information Center

    Slawski, Carl

    A policy systems theoretical analysis of the problem of institutionalizing innovation in an organization is summarized in a flow diagram. The model is presented in terms of specific hypotheses, and then illustrated with a case of frustrated innovation, the 1968-69 crisis and strike at San Francisco State College. The model is set up (1) to help…

  10. Eutrophication status of the North Sea, Skagerrak, Kattegat and the Baltic Sea in present and future climates: A model study

    NASA Astrophysics Data System (ADS)

    Skogen, Morten D.; Eilola, Kari; Hansen, Jørgen L. S.; Meier, H. E. Markus; Molchanov, Mikhail S.; Ryabchenko, Vladimir A.

    2014-04-01

    A method to combine observations and an ensemble of ecological models has been used to assess eutrophication. Using downscaled forcing from two GCMs under the A1B emission scenario, an assessment of the eutrophication status was made for a control (1970-2000) and a future climate (2070-2100) period. By using validation results from a hindcast to compute individual weights between the models, an assessment of eutrophication is done using a set of threshold values. The final classification distinguishes between three categories: problem area, potential problem area, and non-problem area, in accordance with current management practice as suggested by the Oslo and Paris Commissions (OSPAR) and the Helsinki Commission (HELCOM). For the control run the assessment indicates that the Kattegat, the Danish Straits, the Gulf of Finland, the Gotland Basin as well as main parts of the Arkona Basin, the Bornholm Basin, and the Baltic proper may be classified as problem areas. The main part of the North Sea and also the Skagerrak are non-problem areas while the main parts of the Gulf of Bothnia, Gulf of Riga and the entire southeastern continental coast of the North Sea may be classified as potential problem areas. In the future climate scenarios most of the previous potential problem areas in the Baltic Sea have become problem areas, except for the Bothnian Bay where the situation remain fairly unchanged. In the North Sea there seems to be no obvious changes in eutrophication status in the projected future climate.

  11. An Adaptive Sequential Design for Model Discrimination and Parameter Estimation in Non-Linear Nested Models

    SciTech Connect

    Tommasi, C.; May, C.

    2010-09-30

    The DKL-optimality criterion has been recently proposed for the dual problem of model discrimination and parameter estimation, for the case of two rival models. A sequential version of the DKL-optimality criterion is herein proposed in order to discriminate and efficiently estimate more than two nested non-linear models. Our sequential method is inspired by the procedure of Biswas and Chaudhuri (2002), which is however useful only in the set up of nested linear models.

  12. Setting up Academies, Campaigning against Them: An Analysis of a Contested Policy Process

    ERIC Educational Resources Information Center

    Hatcher, Richard

    2009-01-01

    Academies have proved to be one of the most contentious of the Labour government's education policies. The education policies of the Labour government, including Academies, have been the subject of a large body of academic research and analysis, much of it critical. However, it has tended to neglect popular dissent and movements of opposition.…

  13. Primary Care in a Rural Set Up in Nepal: Perspectives of a Generalist

    PubMed Central

    Basnyat, Amogh

    2013-01-01

    This article deals with the author's personal perspectives while having to serve as a generalist in a rural hospital in one of the most underdeveloped and far away regions of Nepal. Having been deputed in Kalikot District Hospital (KDH) through Nick Simons Institute's (NSI) Rural Staff Support Program (RSSP), the author mentions the technical hardships and resource constraints of the government hospital. Highlighting the improvement in the hospital profile after the arrival of the RSSP, the article cursorily mentions the modalities of primary care spanning the common clinical presentations. Particularly, the difficulties related to the provision of Comprehensive Emergency Obstetric Care (CEOC) services are highlighted. Also, a brief introduction as to the NSI, Kathmandu is provided. PMID:24479086

  14. Throttle control linkage for internal combustion engines and method of set-up

    SciTech Connect

    Hendron, S.S.; Williams, N.E.

    1992-10-06

    This patent describes throttle control linkage for an internal combustion engine having a pivotally-mounted injector lever for movement between a first predetermined position and a second predetermined position to control a fuel injector pump; It comprises: a throttle control lever mounted for movement between a first predetermined position and a second predetermined position; a pivotally-mounted bellcrank having an arcuate slot formed therein; first linkage means operatively connected between the arcuate slot and the pivotally-mounted injector lever; the arcuate slot formed along a predetermined radius from the connection of the second linkage means on the pivotally-mounted injector lever when the throttle control lever and the pivotally-mounted injector lever are positioned in the first predetermined position.

  15. Pipeline hub project sets up gas service for U. S. West Coast markets

    SciTech Connect

    Murdock, P.J. )

    1990-08-06

    This paper reports how a major reconfiguration of a West Texas pipeline hub will allow the operator significant flexibility in transporting natural gas either to U.S. West Coast markets or to similar pipeline hubs in central and East Texas for movement to midwestern or eastern U.S. markets. The pipeline system is configured to transport natural gas between three major pipeline hubs in Texas: Carthage (Panola County), Katy (Waller County), and Waha (Pecos County).

  16. Imaging in bariatric surgery: service set-up, post-operative anatomy and complications

    PubMed Central

    Shah, S; Shah, V; Ahmed, A R; Blunt, D M

    2011-01-01

    Obesity is an increasingly prevalent and costly problem faced by the healthcare system. The role of bariatric surgery in managing obesity has also increased with evidence showing a reduction in long-term morbidity and mortality. There are unique challenges faced by the radiology department in providing an imaging service for this population of patients, from technical and staffing requirements through to the interpretation of challenging post-surgical images. We describe these challenges and provide an overview of the most frequently performed procedures, normal post-operative imaging findings and the appearance of common complications. PMID:21045066

  17. A Fully Immersive Set-Up for Remote Interaction and Neurorehabilitation Based on Virtual Body Ownership

    PubMed Central

    Perez-Marcos, Daniel; Solazzi, Massimiliano; Steptoe, William; Oyekoya, Oyewole; Frisoli, Antonio; Weyrich, Tim; Steed, Anthony; Tecchia, Franco; Slater, Mel; Sanchez-Vives, Maria V.

    2012-01-01

    Although telerehabilitation systems represent one of the most technologically appealing clinical solutions for the immediate future, they still present limitations that prevent their standardization. Here we propose an integrated approach that includes three key and novel factors: (a) fully immersive virtual environments, including virtual body representation and ownership; (b) multimodal interaction with remote people and virtual objects including haptic interaction; and (c) a physical representation of the patient at the hospital through embodiment agents (e.g., as a physical robot). The importance of secure and rapid communication between the nodes is also stressed and an example implemented solution is described. Finally, we discuss the proposed approach with reference to the existing literature and systems. PMID:22787454

  18. Setting up Suicide Prevention Plans at the Local Level: The Methodology of Focus Groups with Stakeholders

    ERIC Educational Resources Information Center

    Poma, Stefano Zanone; Grossi, Antonello; Venturini, Monica; Cristina, Contessa; Toniolo, Emanuele

    2011-01-01

    In the prevention of suicide, there is a need to transform clinical studies into health promotion by a cooperation with territorial agencies. A survey on a group of stakeholders was performed with the methodology of focus group. The evaluation criteria used by the participants were practical and not methodological and were closely linked to the…

  19. Setting up a Rayleigh Scattering Based Flow Measuring System in a Large Nozzle Testing Facility

    NASA Technical Reports Server (NTRS)

    Panda, Jayanta; Gomez, Carlos R.

    2002-01-01

    A molecular Rayleigh scattering based air density measurement system has been built in a large nozzle testing facility at NASA Glenn Research Center. The technique depends on the light scattering by gas molecules present in air; no artificial seeding is required. Light from a single mode, continuous wave laser was transmitted to the nozzle facility by optical fiber, and light scattered by gas molecules, at various points along the laser beam, is collected and measured by photon-counting electronics. By placing the laser beam and collection optics on synchronized traversing units, the point measurement technique is made effective for surveying density variation over a cross-section of the nozzle plume. Various difficulties associated with dust particles, stray light, high noise level and vibration are discussed. Finally, a limited amount of data from an underexpanded jet are presented and compared with expected variations to validate the technique.

  20. LINC-NIRVANA for the LBT: setting up the world's largest NIR binoculars for astronomy

    NASA Astrophysics Data System (ADS)

    Hofferbert, Ralph; Baumeister, Harald; Bertram, Thomas; Berwein, Jürgen; Bizenberger, Peter; Böhm, Armin; Böhm, Michael; Borelli, José Luis; Brangier, Matthieu; Briegel, Florian; Conrad, Albert; De Bonis, Fulvio; Follert, Roman; Herbst, Tom; Huber, Armin; Kittmann, Frank; Kürster, Martin; Laun, Werner; Mall, Ulrich; Meschke, Daniel; Mohr, Lars; Naranjo, Vianak; Pavlov, Aleksei; Pott, Jörg-Uwe; Rix, Hans-Walter; Rohloff, Ralf-Rainer; Schinnerer, Eva; Storz, Clemens; Trowitzsch, Jan; Yan, Zhaojun; Zhang, Xianyu; Eckart, Andreas; Horrobin, Matthew; Rost, Steffen; Straubmeier, Christian; Wank, Imke; Zuther, Jens; Beckmann, Udo; Connot, Claus; Heininger, Matthias; Hofmann, Karl-Heinz; Kröner, Tim; Nussbaum, Eddy; Schertl, Dieter; Weigelt, Gerd; Bergomi, Maria; Brunelli, Alessandro; Dima, Marco; Farinato, Jacopo; Magrin, Demetrio; Marafatto, Luca; Ragazzoni, Roberto; Viotto, Valentina; Arcidiacono, Carmelo; Bregoli, Giovanni; Ciliegi, Paolo; Cosentino, Guiseppe; Diolaiti, Emiliano; Foppiani, Italo; Lombini, Matteo; Schreiber, Laura; D'Alessio, Francesco; Li Causi, Gianluca; Lorenzetti, Dario; Vitali, Fabrizio; Bertero, Mario; Boccacci, Patrizia; La Camera, Andrea

    2012-10-01

    LINC-NIRVANA (LN) is the near-infrared, Fizeau-type imaging interferometer for the Large Binocular Telescope (LBT) on Mt. Graham, Arizona, USA (3267m of elevation). The instrument is currently being built by a consortium of German and Italian institutes under the leadership of the Max Planck Institute for Astronomy (MPIA) in Heidelberg, Germany. It will combine the radiation from both 8.4m primary mirrors of LBT in such a way that the sensitivity of a 11.9m telescope and the spatial resolution of a 22.8m telescope will be obtained within a 10.5arcsec x 10.5arcsec scientific field of view. Interferometric fringes of the combined beams are tracked in an oval field with diameters of 1 and 1.5arcmin. In addition, both incoming beams are individually corrected by LN's multi-conjugate adaptive optics (MCAO) system to reduce atmospheric image distortion over a circular field of up to 6arcmin in diameter. This paper gives a comprehensive technical overview of the instrument comprising the detailed design of LN's four major systems for interferometric imaging and fringe tracking, both in the NIR range of 1 - 2.4μm, as well as atmospheric turbulence correction at two altitudes, both in the visible range of 0.6 - 0.9μm. The resulting performance capabilities and a short outlook of some of the major science goals will be presented. In addition, the roadmap for the related assembly, integration and verification (AIV) process will be discussed. To avoid late interface-related risks, strategies for early hardware as well as software interactions with the telescope have been elaborated. The goal is to ship LN to the LBT in 2014.

  1. A Python tool to set up relative free energy calculations in GROMACS.

    PubMed

    Klimovich, Pavel V; Mobley, David L

    2015-11-01

    Free energy calculations based on molecular dynamics (MD) simulations have seen a tremendous growth in the last decade. However, it is still difficult and tedious to set them up in an automated manner, as the majority of the present-day MD simulation packages lack that functionality. Relative free energy calculations are a particular challenge for several reasons, including the problem of finding a common substructure and mapping the transformation to be applied. Here we present a tool, alchemical-setup.py, that automatically generates all the input files needed to perform relative solvation and binding free energy calculations with the MD package GROMACS. When combined with Lead Optimization Mapper (LOMAP; Liu et al. in J Comput Aided Mol Des 27(9):755-770, 2013), recently developed in our group, alchemical-setup.py allows fully automated setup of relative free energy calculations in GROMACS. Taking a graph of the planned calculations and a mapping, both computed by LOMAP, our tool generates the topology and coordinate files needed to perform relative free energy calculations for a given set of molecules, and provides a set of simulation input parameters. The tool was validated by performing relative hydration free energy calculations for a handful of molecules from the SAMPL4 challenge (Mobley et al. in J Comput Aided Mol Des 28(4):135-150, 2014). Good agreement with previously published results and the straightforward way in which free energy calculations can be conducted make alchemical-setup.py a promising tool for automated setup of relative solvation and binding free energy calculations. PMID:26487189

  2. Quality of healthcare related software applications--setting up an accreditation system in Hungary.

    PubMed

    Lakner, G; Balkányi, L; Surján, G; Kovács, J

    1997-01-01

    Meeting expectations of high quality health care, the safe and secure operation of medical information systems is a "must". However for healthcare software nationwide quality control systems are not widely used. A quality control project of health care applications in Hungary has been launched in 1996 by the Hungarian Society of Healthcare Informatics (MEIT) and Medico-Biological Section of Johann Neumann Society of Computing (NJSZT) by establishing a joint Healthcare Informatics Applications Accreditation Board (Board ESAB). The Board developed an evaluation methodology and a legal procedure to test health care software application modules. The evaluation method is based on international standards as ISO-9126 and on emerging European standards of CEN/TC 251. First rounds of accreditation already proved that there is a need among providers and users for the accreditation process. The authors hope that establishing an accreditation system will lead to a more balanced health care software market where users have an opportunity to inform themselves by the opinion of independent experts on the product they intend to purchase.

  3. Setting up the On-Site Marriage and Family Therapy Clinical Training Course

    ERIC Educational Resources Information Center

    Ratanasiripong, Paul; Ghafoori, Bita

    2009-01-01

    The first clinical training experience or practicum for graduate students in a Marriage and Family Therapy (MFT) program is one of the most important aspects of the entire training program. After a year-long journey through textbook and classroom knowledge, students have the opportunity to finally apply their skills to real life environments with…

  4. Two Ways to Set Up Wireless Hotspot: Comparing Apples and Oranges

    ERIC Educational Resources Information Center

    Mutch, Andrew; Ventura, Karen

    2006-01-01

    Every place has it--coffee shops, bookstores, universities ... and now libraries are offering wireless Internet access too. At the Waterford Township Public Library (Waterford, Michigan), Andrew Mutch created a wide-open wireless network using Public IP open source software. About 20 miles away, at the Novi Public Library (Novi, Michigan), Karen…

  5. Setting up the drying regimes based on the theory of moisture migration during drying

    NASA Astrophysics Data System (ADS)

    Vasić, M.; Radojević, Z.

    2016-08-01

    Drying is energy intensive process which has important effect on the quality of the clay tiles that are dried commercially. Chamber and tunnel dryers are constantly improving. Better technical equipment and operational strategies have lead to higher quality of the dried clay products. The moisture migration during isothermal drying process can be visually traced on the curve that represents the relationship between variable effective moisture diffusivity (MR) with time (t). Proposed non isothermal drying regimes were consisted from several isothermal segments. For the first time, the choice of isothermal segments specification and its duration was not specified by experience or by trial-and-error method. It was detected from the isothermal curves Deff - MR in accordance with the theory of moisture migration during drying. Proposed drying regimes were tested. Clay roofing tiles were dried without cracks. Dried clay roofing tiles has satisfied all requirements defined in EN 1304 norm related to the shape regularity and mechanical properties.

  6. CTEPP STANDARD OPERATING PROCEDURE FOR SETTING UP A HOUSEHOLD SAMPLING SCHEDULE (SOP-2.10)

    EPA Science Inventory

    This SOP describes the method for scheduling study subjects for field sampling activities in North Carolina (NC) and Ohio (OH). There are three field sampling teams with two staff members on each team. Two field sampling teams collect the field data simultaneously. A third fiel...

  7. Tenure Track Athletic Training Educators: Are They Being Set Up to Fail?

    ERIC Educational Resources Information Center

    Dewald, Lori; Walsh, Katie

    2009-01-01

    Issues faced by tenure track AT education faculty are addressed and suggestions for those who are considering appointments as AT faculty are given. Literature and research from other allied health professions are provided as insights to AT faculty. We also suggest future research ideas related to AT educators. Finally, we consider future…

  8. External beam IBA set-up with large-area thin Si3N4 window

    NASA Astrophysics Data System (ADS)

    Palonen, V.; Mizohata, K.; Nissinen, T.; Räisänen, J.

    2016-08-01

    A compact external beam setup has been constructed for Particle Induced X-ray Emission (PIXE) and Nuclear Reaction (NRA) analyses. The key issue in the design has been to obtain a wide beam spot size with maximized beam current utilizing a thin Si3N4 exit window. The employed specific exit window support enables use of foils with thickness of 100 nm for a beam spot size of 4 mm in diameter. The durable thin foil and the large beam spot size will be especially important for the complementary external beam NRA measurements. The path between the exit foil and sample is filled with flowing helium to minimize radiation hazard as well as energy loss and straggling, and to cool the samples. For sample-independent beam current monitoring and irradiation fluence measurement, indirect charge integration, based on secondary electron current measurement from a beam profilometer, is utilized.

  9. Setting up the critical rainfall line for debris flows via support vector machines

    NASA Astrophysics Data System (ADS)

    Tsai, Y. F.; Chan, C. H.; Chang, C. H.

    2015-10-01

    The Chi-Chi earthquake in 1999 caused tremendous landslides which triggered many debris flows and resulted in significant loss of public lives and property. To prevent the disaster of debris flow, setting a critical rainfall line for each debris-flow stream is necessary. Firstly, 8 predisposing factors of debris flow were used to cluster 377 streams which have similar rainfall lines into 7 groups via the genetic algorithm. Then, support vector machines (SVM) were applied to setup the critical rainfall line for debris flows. SVM is a machine learning approach proposed based on statistical learning theory and has been widely used on pattern recognition and regression. This theory raises the generalized ability of learning mechanisms according to the minimum structural risk. Therefore, the advantage of using SVM can obtain results of minimized error rates without many training samples. Finally, the experimental results confirm that SVM method performs well in setting a critical rainfall line for each group of debris-flow streams.

  10. How to Set Up a Resource Center to be Compatible with an Outdoor Program.

    ERIC Educational Resources Information Center

    Stilson, Jan

    A materials collection can provide indirect experiences that will supplement the direct learning experiences offered by an outdoor education nature center. The Instructional Materials Center at Lorado Taft Field Campus provides such multiple learning experiences as it offers print media as well as slides, films, tapes, and projection and field…

  11. How to Set Up Simulations for Designing Light-Weight Personalised Recommender Systems

    NASA Astrophysics Data System (ADS)

    Nadolski, Rob; van den Berg, Bert; Berlanga, Adriana; Hummel, Hans; Drachsler, Hendrik; Koper, Rob; Sloep, Peter

    For effective competence acquisition, professionals should have a clear overview of what learning actions (LAs) are relevant to them. LAs can use any type of learning resource or events (like a course, assignment, discussion, lesson, website, blog) that intends to help learners to acquire a certain competence when participating in a LN. Such learners need advice in choosing from a large and dynamic collection of LAs those that best fit their current needs and accomplishments. In short, they need support to find their way in a LN.

  12. Setting Up a Special Collection on Water Pollution in a University Library

    ERIC Educational Resources Information Center

    Friedlander, Janet

    1974-01-01

    The establishment of a special collection within the university library, the complexities of identifying and collecting reports in the environmental area, locating agencies concerned with water pollution, and recording the location of other local collections of data are described. (Author)

  13. Fretting-corrosion in Hip Implant Modular Junctions: New Experimental Set-up and Initial Outcome

    PubMed Central

    Royhman, D.; Patel, M.; Runa, M.J.; Jacobs, J.J.; Hallab, N.J.; Wimmer, M.A.; Mathew, M.T.

    2015-01-01

    Modern hip prostheses feature a modular implant design with at least one tapered junction. This design can lead to several complications due to the introduction of additional interfaces, which are subjected to various loading conditions and micromotion. The main objective of current study is to develop a fretting corrosion apparatus, which is able characterize the mechanical and electrochemical behaviour of various existing metal alloy couples during fretting motion. This study describes the design and the main considerations during the development of a novel fretting corrosion apparatus, as well as determination of the machine compliance and the initial testing results. Machine compliance considerations and frictional interactions of the couples are discussed in detail. For the preliminary tests, metal alloy pins, made of Ti6Al4V and wrought high-carbon CoCrMo were mechanically polished to a surface roughness of less than 20nm. 2 pins (Diameter = 11mm) of either Ti6Al4V or CoCrMo were loaded onto a Ti6Al4V alloy rod at a normal force of 200N. The interface types included: Ti6Al4V-Ti6Al4V-Ti6Al4V, Ti6Al4V-Ti6Al4V-CoCrMo, and CoCrMo-Ti6Al4V-CoCrMo. The Ti6Al4V rod articulated against the metal alloy pins in a sinusoidal fretting motion with a displacement amplitude of ±50μm. Bovine calf serum (30g/L of protein content) was selected as a lubricant and tested at 2 different pH levels (pH 3.0 and 7.6). In all cases, current and friction energy were monitored during the fretting process. The results indicated distinct, material-specific current evolutions and friction energies. No significant differences were observed in electrochemical or mechanical behaviour in response to pH change. In general, Ti6Al4V-Ti6Al4V-Ti6Al4V couples displayed the earliest passivation and superior electrochemical behaviour compared to Ti6Al4V-Ti6Al4V-CoCrMo and CoCrMo-Ti6Al4V-CoCrMo under fretting conditions. In addition, fluctuations in current were observed in specific regions at all instances where Ti6Al4V was coupled with Ti6Al4V. These fluctuations were not observed in instances where Ti6Al4V was coupled with CoCrMo. These findings suggest transitions in the degradation mechanisms at the modular junction as a function of material couples/contacts. The findings may assist in improving the current hip modular junctions. PMID:26405372

  14. Constrained set-up of the tGAP structure for progressive vector data transfer

    NASA Astrophysics Data System (ADS)

    Haunert, Jan-Henrik; Dilo, Arta; van Oosterom, Peter

    2009-11-01

    A promising approach to submit a vector map from a server to a mobile client is to send a coarse representation first, which then is incrementally refined. We consider the problem of defining a sequence of such increments for areas of different land-cover classes in a planar partition. In order to submit well-generalised datasets, we propose a method of two stages: First, we create a generalised representation from a detailed dataset, using an optimisation approach that satisfies certain cartographic constraints. Second, we define a sequence of basic merge and simplification operations that transforms the most detailed dataset gradually into the generalised dataset. The obtained sequence of gradual transformations is stored without geometrical redundancy in a structure that builds up on the previously developed tGAP (topological Generalised Area Partitioning) structure. This structure and the algorithm for intermediate levels of detail (LoD) have been implemented in an object-relational database and tested for land-cover data from the official German topographic dataset ATKIS at scale 1:50 000 to the target scale 1:250 000. Results of these tests allow us to conclude that the data at lowest LoD and at intermediate LoDs is well generalised. Applying specialised heuristics the applied optimisation method copes with large datasets; the tGAP structure allows users to efficiently query and retrieve a dataset at a specified LoD. Data are sent progressively from the server to the client: First a coarse representation is sent, which is refined until the requested LoD is reached.

  15. An RFI investigation for setting up a VLBI station below 2.8 GHz in Malaysia

    NASA Astrophysics Data System (ADS)

    Abidin, Zamri Zainal; Ibrahim, Zainol Abidin; Rosli, Zulfazli; Malim, Siti Fatin Fathinah; Anim, Norsuzian Mohd; Noorazlan, Noorkhallaf

    2012-02-01

    In this paper, we investigated the radio frequency interference (RFI) that future Very Long Baseline Interferometer (VLBI) observations in Malaysia may encounter. Four frequency windows below 2.8 GHz were chosen for this study and their spectra were measured at four sites. The frequency windows are 322-328 MHz, 608-614 MHz, 1660-1660.5 MHz and 1660.5-1668.4 MHz. The measured averaged RFI floor noise levels in these windows are -99.992 (±0.570) dBm, -99.907 (±0.639) dBm, -100.220 (±0.4941) dBm and -100.359 (±0.110) dBm, respectively. We found that only two bands below 2.8 GHz are permitted for the purpose of radio astronomy in Malaysia. They are 608-614 MHz and 1660-1660.5 MHz. The RFI levels in these permissible bands at the best site (Langkawi) were also measured and concluded to be relatively low. Main sources of RFI in these bands in Malaysia were identified. We also reviewed several current VLBI observations in these two bands.

  16. Characterisation of the half-field beam penumbra for a variety of blocking set-ups

    NASA Astrophysics Data System (ADS)

    Smith, S. T.; Kairn, T.; Crowe, S. B.; Asena, A.; Trapp, J. V.

    2015-01-01

    Measurements of half-field beam penumbra were taken using EBT2 film for a variety of blocking techniques. It was shown that minimizing the SSD reduces the penumbra as the effects of beam divergence are diminished. The addition of a lead block directly on the surface provides optimal results with a 10-90% penumbra of 0.53 ± 0.02 cm. To resolve the uncertainties encountered in film measurements, future Monte Carlo measurements of halffield penumbras are to be conducted.

  17. A Python tool to set up relative free energy calculations in GROMACS.

    PubMed

    Klimovich, Pavel V; Mobley, David L

    2015-11-01

    Free energy calculations based on molecular dynamics (MD) simulations have seen a tremendous growth in the last decade. However, it is still difficult and tedious to set them up in an automated manner, as the majority of the present-day MD simulation packages lack that functionality. Relative free energy calculations are a particular challenge for several reasons, including the problem of finding a common substructure and mapping the transformation to be applied. Here we present a tool, alchemical-setup.py, that automatically generates all the input files needed to perform relative solvation and binding free energy calculations with the MD package GROMACS. When combined with Lead Optimization Mapper (LOMAP; Liu et al. in J Comput Aided Mol Des 27(9):755-770, 2013), recently developed in our group, alchemical-setup.py allows fully automated setup of relative free energy calculations in GROMACS. Taking a graph of the planned calculations and a mapping, both computed by LOMAP, our tool generates the topology and coordinate files needed to perform relative free energy calculations for a given set of molecules, and provides a set of simulation input parameters. The tool was validated by performing relative hydration free energy calculations for a handful of molecules from the SAMPL4 challenge (Mobley et al. in J Comput Aided Mol Des 28(4):135-150, 2014). Good agreement with previously published results and the straightforward way in which free energy calculations can be conducted make alchemical-setup.py a promising tool for automated setup of relative solvation and binding free energy calculations.

  18. Setting Up a Library Accessible Area for the Blind or Visually Impaired: Considerations.

    ERIC Educational Resources Information Center

    Henson, Dawn

    1997-01-01

    Discusses library planning for services for blind and visually impaired users, including access needs of patrons, available library space, appropriate adaptive technology, equipment costs and budget resources, Internet access, and staff training. A list of pertinent resources is appended. (LRW)

  19. Setting up a mobile Lidar (DIAL) system for detecting chemical warfare agents

    NASA Astrophysics Data System (ADS)

    Kavosh Tehrani, M.; Mohammad, M. Malek; Jaafari, E.; Mobashery, A.

    2015-03-01

    The mobile light detection and ranging DIAL system of Malek Ashtar University of Technology has been developed for the detection of chemical warfare agents whose absorption wavelengths are in the range of 9.2-10.8 μm tunable CO2 lasers of the system. In this paper, this system is first described and then ammonia detection is analyzed experimentally. Also, experimental results of detecting a sarin agent simulant, dimethyl-methyl phosphonate (DMMP), are presented. The power levels received from different ranges to detect specific concentrations of NH3 and DMMP have been measured and debated. The primary test results with a 150 ns clipped pulse width by passive pinhole plasma shutter indicate that the system is capable of monitoring several species of pollutants in the range of about 1 km, with a 20 m spatial and 2 min temporal resolution.

  20. HPC in a HEP lab: lessons learned from setting up cost-effective HPC clusters

    NASA Astrophysics Data System (ADS)

    Husejko, Michal; Agtzidis, Ioannis; Baehler, Pierre; Dul, Tadeusz; Evans, John; Himyr, Nils; Meinhard, Helge

    2015-12-01

    In this paper we present our findings gathered during the evaluation and testing of Windows Server High-Performance Computing (Windows HPC) in view of potentially using it as a production HPC system for engineering applications. The Windows HPC package, an extension of Microsofts Windows Server product, provides all essential interfaces, utilities and management functionality for creating, operating and monitoring a Windows-based HPC cluster infrastructure. The evaluation and test phase was focused on verifying the functionalities of Windows HPC, its performance, support of commercial tools and the integration with the users work environment. We describe constraints imposed by the way the CERN Data Centre is operated, licensing for engineering tools and scalability and behaviour of the HPC engineering applications used at CERN. We will present an initial set of requirements, which were created based on the above constraints and requests from the CERN engineering user community. We will explain how we have configured Windows HPC clusters to provide job scheduling functionalities required to support the CERN engineering user community, quality of service, user- and project-based priorities, and fair access to limited resources. Finally, we will present several performance tests we carried out to verify Windows HPC performance and scalability.

  1. [Experience in setting up a morbid anatomy bureau in the Gomel Region, Republic of Belarus].

    PubMed

    Golubev, O A

    2006-01-01

    A diversity of the clinical and morphological manifestations pf melanoma determines the great importance of each description of manifestation of this most malignant tumor. In this connection, there is a worldwide increasing rise in the number of patients with melanoma whose diagnosis present well-known difficulties, the authors describe a case of this tumor progression, which masked as uterine carcinoma.

  2. Set Up and Test Results for a Vibrating Wire System for Quadrupole Fiducialization

    SciTech Connect

    Not Available

    2010-11-29

    Quadrupoles will be placed between the undulator segments in LCLS to keep the electron beam focused as it passes through. The quadrupoles will be assembled with their respective undulator segments prior to being placed into the tunnel. Beam alignment will be used to center the quadrupoles, along with the corresponding undulators, on the beam. If there is any displacement between the undulator and the quadrupole axes in the assemblies, the beam will deviate from the undulator axis. If it deviates by more than 80{micro}m in vertical or 140{micro}m in horizontal directions, the undulator will not perform as required by LCLS. This error is divided between three sources: undulator axis fiducialization, quadrupole magnetic axis fiducialization, and assembly of the two parts. In particular, it was calculated that the quadrupole needs to be fiducialized to within 25{micro}m in both vertical and horizontal directions. A previous study suggested using a vibrating wire system for finding the magnetic axis of a quadrupole. The study showed that the method has high sensitivity (up to 1{micro}m) and laid out guidelines for constructing it. There are 3 steps in fiducializing the quadrupole with the vibrating wire system. They are positioning the wire at the magnet center (step 1), finding the wire with position detectors (step 2), and finding the quadrupole tooling ball positions relative to the position detector tooling balls (step 3). The following break up of error was suggested for the fiducialization steps: 10{micro}m for step 1 (finding the center), 20{micro}m for step 2 (finding the wire), and 10{micro}m for step 3 (tooling ball measurements). The purpose of this study is to investigate whether the vibrating wire system meets the requirements for LCLS. In particular, if it can reliably fiducialize a quadrupole magnetic center to within 25{micro}m in both vertical and horizontal directions. The behavior of individual system components is compared to the expected performance. A vibrating wire system was constructed to fiducialize the quadrupoles between undulator segments in the LCLS. This note studies the ability of the system to fulfill the fiducialization requirements.

  3. Set Up and Test Results for a Vibrating Wire System for Quadrupole Fiducialization

    SciTech Connect

    Levashov, Michael Y.

    2010-12-01

    Quadrupoles will be placed between the undulator segments in LCLS to keep the electron beam focused as it passes through. The quadrupoles will be assembled with their respective undulator segments prior to being placed into the tunnel. Beam alignment will be used to center the quadrupoles, along with the corresponding undulators, on the beam. If there is any displacement between the undulator and the quadrupole axes in the assemblies, the beam will deviate from the undulator axis. If it deviates by more than 80{micro}m in vertical or 140{micro}m in horizontal directions, the undulator will not perform as required by LCLS. This error is divided between three sources: undulator axis fiducialization, quadrupole magnetic axis fiducialization, and assembly of the two parts. In particular, it was calculated that the quadrupole needs to be fiducialized to within 25{micro}m in both vertical and horizontal directions. A previous study suggested using a vibrating wire system for finding the magnetic axis of a quadrupole. The study showed that the method has high sensitivity (up to 1{micro}m) and laid out guidelines for constructing it. There are 3 steps in fiducializing the quadrupole with the vibrating wire system. They are positioning the wire at the magnet center (step 1), finding the wire with position detectors (step 2), and finding the quadrupole tooling ball positions relative to the position detector tooling balls (step 3). The following break up of error was suggested for the fiducialization steps: 10{micro}m for step 1 (finding the center), 20{micro}m for step 2 (finding the wire), and 10{micro}m for step 3 (tooling ball measurements). The purpose of this study is to investigate whether the vibrating wire system meets the requirements for LCLS. In particular, if it can reliably fiducialize a quadrupole magnetic center to within 25{micro}m in both vertical and horizontal directions. The behavior of individual system components is compared to the expected performance. A vibrating wire system was constructed to fiducialize the quadrupoles between undulator segments in the LCLS. This note studies the ability of the system to fulfill the fiducialization requirements.

  4. STS-35 Payload Specialist Parise sets up SAREX on OV-102's middeck

    NASA Technical Reports Server (NTRS)

    1990-01-01

    STS-35 Payload Specialist Ronald A. Parise enters data into the payload and general support computer (PGSC) in preparation for Earth communication via the Shuttle Amateur Radio Experiment (SAREX) aboard Columbia, Orbiter Vehicle (OV) 102. The SAREX equipment is secured to the middeck starboard sleep station. SAREX provided radio transmissions between ground based amateur radio operators around the world and Parise, a licensed amateur radio operator. The experiment enabled students to communicate with an astronaut in space, as Parise (call-sign WA4SIR) devoted some of his off-duty time to that purpose. Displayed on the forward lockers beside Parise is a AMSAT (Amateur Radio Satellite Corporation) / ARRL (American Radio Relay League) banner. Food items and checklists are attached to the lockers. In locker position MF43G, the Development Test Objective (DTO) Trash Compaction and Retention System Demonstration extended duration orbiter (EDO) compactor is visible.

  5. [Three types of brand name loyalty strategies set up by drug manufacturers].

    PubMed

    PréMont, Marie-Claude; Gagnon, Marc-André

    2014-11-01

    The recent restructuring of the pharmaceutical industry has led to three new types of promotional strategies to build patient loyalty to brand name drugs: loyalty through rebates, patient support, and compassion programs. Loyalty through rebates seeks to keep patients on a brand name drug and prevent their switch to the generic equivalent. Loyalty through patient support provides aftersales services to help and support patients (by phone or home visits) in order to improve adherence to their treatments. Finally, compassion programs offer patients access to drugs still awaiting regulatory approval or reimbursement by insurers. When and if the approval process is successful, the manufacturer puts an end to the compassion program and benefits from a significant cohort of patients already taking a very expensive drug for which reimbursement is assured. The impact of these programs on public policies and patients' rights raises numerous concerns, among which the direct access to patients and their health information by drug manufacturers and upward pressure on costs for drug insurance plans. PMID:25617517

  6. A Guide to Setting up a College Bereavement Group: Using Monologue, Soliloquy, and Dialogue

    ERIC Educational Resources Information Center

    Prior, Alexandra

    2015-01-01

    Childhood grief disrupts and reshapes a developing child's primary attachments, emotional regulation system, and identity formation. Bereft college students have to build their grief identity simultaneously with their social, academic, vocational, and sexual identities. This article describes a bereavement group to help students work on these…

  7. Cooperation between Japanese and Cambodian Dietitians in Setting up a Hospital Diet Management System.

    PubMed

    Ly, Koung Ry; Saito, Shino; Kusama, Kaoru

    2015-01-01

    Cambodia faces a considerably high percentage of the stunted under 5 (Unicef, 2014). Despite the National Nutrition Strategy Launched by the Ministry of Health in cooperation with development partners, nutrition improvement projects have not always been effective. It is generally said these issues are addressed in many other developing nations, and the literature largely documented that successful nutrition programmes are community-based programmes because of their sustainability and the intensive communications between health workers and beneficiaries. Learning from the past experiences, the Foundation for International Development/Relief organized a project team with a Cambodian dietitian and an experienced Japanese dietitian to implement a hospital diet programme for children from April 2006 to March 2014 in the National Pediatric Hospital (NPH) in Cambodia. The project has two objectives: establishing a hospital diet management system, and developing the capacity of NPH staff. Hospital food menus were created paying particular attention to Cambodian culture, eating habits and accessibility to the ingredients for the purpose of continuous supply. We have also put emphasis on the communication between dietitians and family members of the children to let them understand the importance of a nutritious diet. After 8 y of project implementation, the hospital diet management system was established providing 7 types of menu with nutritious diets. The final evaluation of the project showed that NPH staff have the intention to continue hospital food supply with their acquired knowledge and capacity. In practice, a Cambodian dietitian currently takes the initiative for a continuous nutritional diet in NPH. The key to this success is the collaboration between Japanese dietitians with experience and Cambodian dietitians with knowledge of Cambodian eating habits. Taking our experience into account, it is highly recommended to educate Cambodian dietitians, as they are extremely scarce, and to increase the awareness of health care staff towards the importance of nutrition management. PMID:26598888

  8. Recent developments in the setting up of the Malta Seismic Network

    NASA Astrophysics Data System (ADS)

    Agius, Matthew; Galea, Pauline; D'Amico, Sebastiano

    2015-04-01

    Weak to moderate earthquakes in the Sicily Channel have until now been either poorly located or left undetected. The number of seismic stations operated by various networks: Italy (INGV), Tunisia (TT), and Libya (LNSN) have now improved considerably, however most of the seismicity occurs offshore, in the central part of the Channel, away from the mainland stations. Seismic data availability from island stations across the Channel has been limited or had intermittent transmission hindering proper real-time earthquake monitoring and hypocentre relocation. In order to strengthen the seismic monitoring of the Sicily Channel, in particular the central parts of the Channel, the Seismic Monitoring and Research Unit (SMRU), University of Malta, has, in the last year, been installing a permanent seismic network across the Maltese archipelago: the Malta Seismic Network (ML). Furthermore the SMRU has upgraded its IT facilities to run a virtual regional seismic network composed of the stations on Pantelleria and Lampedusa, together with all the currently publicly available stations in the region. Selected distant seismic stations found elsewhere in the Mediterranean and across the globe have also been incorporated in the system in order to enhance the overall performance of the monitoring and to detect potentially damaging regional earthquakes. Data acquisition and processing of the seismic networks are run by SeisComP. The new installations are part of the project SIMIT (B1-2.19/11) funded by the Italia-Malta Operational Programme 2007-2013. The new system allows the SMRU to rapidly perform more accurate hypocentre locations in the region, and issue automatic SMS alert for potentially felt events in the Sicily Channel detected by the network and for strong earthquakes elsewhere. Within the SIMIT project, the alert system will include civil protection departments in Malta and Sicily. We present the recent developments of the real and virtual seismic network, and discuss the performance of each of the new stations, the general operation of the SMRU, and the alert system. New web features soon available on the SMRU website will be presented.

  9. Pain management: setting up a nurse-led femoral nerve block service.

    PubMed

    Layzell, Mandy

    Managing pain following a fractured neck of femur is challenging for a number of reasons. This group of patients are typically older people and frail with multiple co-morbidities and are often on numerous medications. In addition to a hip fracture, they commonly present with acute medical problems. Fractures cause significant pain, which can be difficult to manage safely and effectively with the traditional analgesics. A femoral nerve block has been shown to be a safe and effective preoperative intervention for managing pain in this patient group while they wait for surgery. This article describes how an acute pain team have developed protocols and training to establish a nurse-led service for providing preoperative femoral nerve blocks to patients with fractured neck of femur. PMID:17851357

  10. Design, set-up and utility of the UK facioscapulohumeral muscular dystrophy patient registry.

    PubMed

    Evangelista, Teresinha; Wood, Libby; Fernandez-Torron, Roberto; Williams, Maggie; Smith, Debbie; Lunt, Peter; Hudson, Judith; Norwood, Fiona; Orrell, Richard; Willis, Tracey; Hilton-Jones, David; Rafferty, Karen; Guglieri, Michela; Lochmüller, Hanns

    2016-07-01

    Facioscapulohumeral dystrophy (FSHD) is a rare inherited neuromuscular disease estimated to affect 1/15,000 people. Through basic research, remarkable progress has been made towards the development of targeted therapies. Patient identification, through registries or other means is essential for trial-readiness. The UK FSHD Patient Registry is a patient initiated registry that collects standardised and internationally agreed dataset of self-reported clinical details combined with professionally verified genetic information. It includes four additional questionnaires to capture patient reported outcomes related to pain, quality of life and scapular fixation. Between 2013 and 2015, 518 patients registered 243 males, 241 females with a mean age of 47.8 years. Most of the patients have FSHD type 1 (91.7 %), and weakness of the facial (59.2 %) was the most prevalent symptom at onset, followed by shoulder-girdle muscles (53.3 %) and distal (22.45 %) or proximal lower limb weakness (14.8 %). 85.57 % patients were ambulant or ambulant with assistance at the time of registration, 7.9 % report respiratory insufficiency. The registry has demonstrated utility with the recruitment of patients for a natural history study of infantile onset FSHD, and the longitudinal analysis of patient-related outcomes will provide much-needed baseline information to power future trials. The internationally agreed core dataset enables national registries to participate in a "Global FSHD registry". We suggest that the registry's ability to interoperate with other large datasets will be instrumental for sharing and exploiting data globally. PMID:27159994

  11. Setting up a scientific community by means of a small grants program: the Latin American experience.

    PubMed

    Briceño-León, R

    1994-08-01

    The study of tropical diseases in Latin America has been dominated by the biomedical sciences, and whilst recently social science health research has been developed, there has been little collaboration between the two. The Latin American Small Grants Programme for Social and Economic Aspects of Tropical Diseases, launched by WHO/TDR in 1990, aimed to attract junior researchers into the area of social sciences and tropical diseases, and to create among them a scientific community. The program is unique in that it has involved the transfer of decision-making power from an international organisation (WHO/TDR) to a regional group. This article discusses the organisational structure of the program, the methods by which the program handled proposals, the evaluation process, the types of research proposals received, a profile of applicants, and the results of the applications. There was a balance of biomedical and social science applications. We conclude that the Small Grants Programme has been successful in fulfilling its objectives, due to the design of the grants scheme itself.

  12. Setting-up a European Cross-Provider Data Collection on Open Online Courses

    ERIC Educational Resources Information Center

    Kalz, Marco; Kreijns, Karel; Walhout, Jaap; Castaño-Munoz, Jonatan; Espasa, Anna; Tovar, Edmundo

    2015-01-01

    While MOOCS have emerged as a new form of open online education around the world, research is stilling lagging behind to come up with a sound theoretical basis that can cover the impact of socio-economic background variables, ICT competences, prior experiences and lifelong learning profile, variance in intentions, environmental influences, outcome…

  13. Careers Using Languages: How to Set up a Conference for Schools

    ERIC Educational Resources Information Center

    Hayes, Alison

    2016-01-01

    Since 2011, York St John University (YSJU) has run an annual one-day "Careers using Languages" conference for schools in Yorkshire and Humberside. It has the aim of demonstrating to school students the opportunities in life that speaking a foreign language opens up as well as showing how they will be able to offer an added bonus to their…

  14. Set-up of a new TDCR counter at IRA-METAS.

    PubMed

    Nedjadi, Youcef; Bailat, Claude; Caffari, Yvan; Cassette, Philippe; Bochud, François

    2015-03-01

    A triple-to-double coincidence ratio (TDCR) counter was recently constructed at IRA-METAS for liquid scintillation based primary activity standardisations. A description of its optical chamber, efficiency change tools, photomultiplier tubes (PMTs) and electronics is given. This TDCR system was validated by measuring several standard solutions of beta emitters including (45)Ca, (14)C, (63)Ni and (3)H. The activity concentrations, obtained from these measurements and efficiencies computed with a FORTRAN code we developed for symmetric and asymmetric PMTs, agree with the certified values within uncertainties. PMID:25569200

  15. Serving to different locations: set-up, toss, and racket kinematics of the professional tennis serve.

    PubMed

    Reid, Machar; Whiteside, David; Elliott, Bruce

    2011-11-01

    The serve, as the most important stroke in tennis, has attracted considerable biomechanical interest. Of its component parts, the swing has received disproportionate research attention and consequently, little is known regarding toss kinematics. Indeed, the age-old question of whether players serve to different parts of the court from the same toss remains unanswered. Six right-handed professionally ranked players hit first serves (FSs) and second serves (SSs) to three 2 x 1 m target areas reflecting the landing locations of T, body and wide serves, respectively, on the deuce court. A 22 camera, 250 Hz VICON MX motion analysis system captured racket, ball, foot, and h and kinematics. Repeated measures ANOVAs assessed within-player differences in foot, racket, and ball kinematics within the FS and SS as a function of landing location. The positions of the front foot, ball zenith, and ball impact were significantly different in the FS, while kinematics across all SS were consistent. Front foot position was closer to the centre mark in the T FS and players impacted the ball further left in the wide FS compared to the T FS. This study discusses the findings in the context of the development of the serve as well as potential implications for the return.

  16. How to Set up Oral Homework: A Case of Limited Technology

    ERIC Educational Resources Information Center

    Mendez, Elba

    2010-01-01

    Homework usually consists of the learners' written account of how they interpreted a task set by the teacher, and is generally defined as out-of-class assignments that are handed in for the instructor to grade. Learners may work individually or with partners to answer simple or challenging linguistic exercises, sketch out a mind map, or develop a…

  17. Set-up and demonstration of a Low Energy Electron Magnetometer (LEEM)

    NASA Technical Reports Server (NTRS)

    Rayborn, G. H.

    1986-01-01

    Described are the design, construction and test results of a Low Energy Electron Magnetometer (LEEM). The electron source is a commercial electron gun capable of providing several microamperes of electron beam. These electrons, after acceleration through a selected potential difference of 100-300 volts, are sent through two 30 degree second-order focussing parallel plate electrostatic analyzers. The first analyzer acts as a monochromator located in the field-free space. It is capable of providing energy resolution of better than 10 to the -3 power. The second analyzer, located in the test field region, acts as the detector for electrons deflected by the test field. The entire magnetometer system is expected to have a resolution of 1 part in 1000 or better.

  18. [Three types of brand name loyalty strategies set up by drug manufacturers].

    PubMed

    PréMont, Marie-Claude; Gagnon, Marc-André

    2014-11-01

    The recent restructuring of the pharmaceutical industry has led to three new types of promotional strategies to build patient loyalty to brand name drugs: loyalty through rebates, patient support, and compassion programs. Loyalty through rebates seeks to keep patients on a brand name drug and prevent their switch to the generic equivalent. Loyalty through patient support provides aftersales services to help and support patients (by phone or home visits) in order to improve adherence to their treatments. Finally, compassion programs offer patients access to drugs still awaiting regulatory approval or reimbursement by insurers. When and if the approval process is successful, the manufacturer puts an end to the compassion program and benefits from a significant cohort of patients already taking a very expensive drug for which reimbursement is assured. The impact of these programs on public policies and patients' rights raises numerous concerns, among which the direct access to patients and their health information by drug manufacturers and upward pressure on costs for drug insurance plans.

  19. State of the art: how to set up a pulmonary rehabilitation program.

    PubMed

    Jenkins, Sue; Hill, Kylie; Cecins, Nola M

    2010-11-01

    Pulmonary rehabilitation plays an essential role in the management of symptomatic patients with COPD. The benefits of rehabilitation include a decrease in dyspnoea and fatigue, and improvements in exercise tolerance and health-related quality of life. Importantly, rehabilitation reduces hospitalization for acute exacerbations and is cost-effective. Although most of the evidence for pulmonary rehabilitation has been obtained in patients with COPD, symptomatic individuals with other respiratory diseases have been shown to benefit. In this review we outline a stepwise approach to establish, deliver and evaluate a pulmonary rehabilitation program (PRP) that would be feasible in most settings. Throughout the review we have specified the minimum requirements for a PRP to facilitate the establishment of programs using limited resources. Recommendations for staffing and other resources required for a PRP are presented in the first section. Exercise training is a focus of the section on program delivery as this is the component of rehabilitation that has the strongest level of evidence for benefit. Program considerations for patients with respiratory conditions other than COPD are described. Different approaches for delivering the education component of a PRP are outlined and recommendations are made regarding topics for group and individual sessions. The problems commonly encountered in pulmonary rehabilitation, together with recommendations to avoid these problems and strategies to assist in their resolution, are discussed. The review concludes with recommendations for evaluating a PRP. PMID:20920127

  20. A rapid slide agglutination test for the diagnosis of neurocysticercosis in the rural health set up

    PubMed Central

    Biswas, Rakhi; Parija, Subhash Chandra

    2011-01-01

    Background: Simple and rapid latex-based diagnostic tests have been used for detecting specific antigens or antibodies in several diseases. Aims: The aim of the present study was to standardize and evaluate the latex agglutination test (LAT) for the detection of Taenia solium metacestode antigen in the cerebrospinal fluid (CSF) and serum for the diagnosis of neurocysticercosis (NCC). Settings and Design: The study was conducted at Department of Microbiology, Jawaharlal Institute of Post graduate medical education and research after obtaining informed consent from the study subjects. Materials and Methods: In the present study, CSF and serum samples were collected from clinically suspected NCC, CT/MRI proven cases of NCC, non-cysticercal central nervous system infection control and from healthy control subjects. CSF was not collected from healthy controls. Polyclonal antisera raised in rabbits against porcine T. solium metacestode complete homogenate antigen, was used in the LAT to detect the antigen in the specimens. Statistical Analysis Used: The statistical analysis was carried out using Epi Info. The sensitivity, specificity, positive predictive value, and negative predictive value of the LAT were calculated. Results: The LAT exhibited sensitivity of 64.7% and specificity of 85.7% with CSF samples and sensitivity of 52.08% and specificity of 96% with serum samples. Conclusions: Results of the present study shows that the LAT can be employed as a moderately sensitive and specific test for the detection of T. solium metacestode antigen in the CSF and serum specimens for the diagnosis of NCC in poorly equipped laboratories. PMID:23508849

  1. The antibiotics of choice for the treatment of melioidosis in Indian set up.

    PubMed

    Shaw, T; Tellapragada, C; Eshwara, V K; Bhat, H V; Mukhopadhyay, C

    2016-01-01

    Therapeutic options for the treatment of melioidosis caused by Burkholderia pseudomallei are limited due to the inherent resistance conferred by this pathogen to various groups of antibiotics. Witnessing an increase in the number of microbiological culture-confirmed cases of melioidosis at our settings in the past few years, we undertook this study to estimate the minimum inhibitory concentrations of clinical isolates of B. pseudomallei against the four commonly employed antimicrobial agents in the patient management at our settings, namely, ceftazidime, meropenem, trimethoprim-sulfamethoxazole and doxycycline. All isolates were susceptible to the antibiotics tested, except for one isolate which showed resistance to doxycycline (minimum inhibitory concentration [MIC]: 32 μg/ml). MIC50 and 90 for all the four antibiotics were estimated. From this study, we conclude that the clinical isolates of B. pseudomallei from the southern part of India are well susceptible to the commonly employed antimicrobial agents for therapy. PMID:27514960

  2. Setting Up CD-ROM Work Areas. Part I: Ergonomic Considerations, User Furniture, Location.

    ERIC Educational Resources Information Center

    Vasi, John; LaGuardia, Cheryl

    1992-01-01

    The first of a two-part series on design of CD-ROM work areas in libraries discusses (1) space and location considerations; (2) ergonomics, including work surface, chairs, lighting, printers, other accessories, and security; and (3) other considerations, including staff assistance, reference tools, literature racks, and promotional materials. (MES)

  3. GEO vs. LEO Space Telecommunication Systems Commercial Set Up, Finance &Economics

    NASA Astrophysics Data System (ADS)

    Kreisel, Joerg

    2002-01-01

    Space-based commercial telecommunication systems - especially in GEO - still represent the big volume segment in commercial space and probably will do so for a while. Although such end-to-end systems both in GEO and LEO are using satellites, ground stations, and service centers, etc., their commercial genesis differs significantly. Based on existing and planned space telecommunication businesses, this paper deals with prime characteristics of commercial GEO and LEO systems and their differences. In a tutorial way the stages of development of both LEO- and GEO-type business ventures are presented. The entire commercial development path is covered (concept, business plan, financing, partnership, growth, etc.). Focus is to understand what drives space telecommunication business and what it takes to start such new commercial space ventures. The perspective given is also based on the author's longstanding background in space commercialization and experiences made as a venture capitalist.

  4. Cooperation between Japanese and Cambodian Dietitians in Setting up a Hospital Diet Management System.

    PubMed

    Ly, Koung Ry; Saito, Shino; Kusama, Kaoru

    2015-01-01

    Cambodia faces a considerably high percentage of the stunted under 5 (Unicef, 2014). Despite the National Nutrition Strategy Launched by the Ministry of Health in cooperation with development partners, nutrition improvement projects have not always been effective. It is generally said these issues are addressed in many other developing nations, and the literature largely documented that successful nutrition programmes are community-based programmes because of their sustainability and the intensive communications between health workers and beneficiaries. Learning from the past experiences, the Foundation for International Development/Relief organized a project team with a Cambodian dietitian and an experienced Japanese dietitian to implement a hospital diet programme for children from April 2006 to March 2014 in the National Pediatric Hospital (NPH) in Cambodia. The project has two objectives: establishing a hospital diet management system, and developing the capacity of NPH staff. Hospital food menus were created paying particular attention to Cambodian culture, eating habits and accessibility to the ingredients for the purpose of continuous supply. We have also put emphasis on the communication between dietitians and family members of the children to let them understand the importance of a nutritious diet. After 8 y of project implementation, the hospital diet management system was established providing 7 types of menu with nutritious diets. The final evaluation of the project showed that NPH staff have the intention to continue hospital food supply with their acquired knowledge and capacity. In practice, a Cambodian dietitian currently takes the initiative for a continuous nutritional diet in NPH. The key to this success is the collaboration between Japanese dietitians with experience and Cambodian dietitians with knowledge of Cambodian eating habits. Taking our experience into account, it is highly recommended to educate Cambodian dietitians, as they are extremely scarce, and to increase the awareness of health care staff towards the importance of nutrition management.

  5. Setting up High Gradient Magnetic Separation for combating eutrophication of inland waters.

    PubMed

    Merino-Martos, A; de Vicente, J; Cruz-Pizarro, L; de Vicente, I

    2011-02-28

    To find new approaches to devise technologies for handling with eutrophication of inland waters is a global challenge. Separation of the P from water under conditions of continuous flow is proposed as an alternative and effective method. This work is based on using highly magnetic particles as the seeding adsorbent material and their later removal from solution by High Gradient Magnetic Separation (HGMS). Contrast to other methods based on batch conditions, large volumes of water can be easily handled by HGMS because of decreasing retention times. This study identifies the best working conditions for removing P from solution by investigating the effects of a set of four different experimental variables: sonication time, flow rate (as it determines the retention time of particles in the magnetic field), magnetic field strength and the iron (Fe) particles/P concentration ratio. Additionally, the change of P removal efficiency with time (build up effect) and the possibility of reusing magnetic particles were also studied. Our results evidenced that while flow rate does not significantly affect P removal efficiency in the range 0.08-0.36 mL s(-1), sonication time, magnetic field strength and the Fe particles/P concentration ratio are the main factors controlling magnetic separation process.

  6. Multiplicity of inhabited worlds and the problem of setting up contacts among them

    NASA Technical Reports Server (NTRS)

    Shklovskiy, I. S.

    1974-01-01

    The numerous planetary systems in our galaxy appear to a high degree of probability to contain some planets with a biosphere similar to earth' environment. The possibility of communicating with those extraterrestrial alien planetary civilizations centers on the high level of technological development that is required to overcome the problem of distance. It is conceivable that advanced civilizations can produce energy at a level of 10 to the 43rd power erg/year and that an artificial biosphere can be developed within the limits of 10 to the 22nd power to 10 to the 23rd power cm.

  7. Setting up a Fee-Based Information Service in an Academic Library

    ERIC Educational Resources Information Center

    Cloutier, C.

    2005-01-01

    In response to local demand, the University of Calgary Library established a fee-based information service for non-university clientele. The benefits from this service have been both intangible and financial. This article reviews the planning and implementation of the service and its future directions.

  8. The implementation of tissue banking experiences for setting up a cGMP cell manufacturing facility.

    PubMed

    Arjmand, Babak; Emami-Razavi, Seyed Hassan; Larijani, Bagher; Norouzi-Javidan, Abbas; Aghayan, Hamid Reza

    2012-12-01

    Cell manufacturing for clinical applications is a unique form of biologics manufacturing that relies on maintenance of stringent work practices designed to ensure product consistency and prevent contamination by microorganisms or by another patient's cells. More extensive, prolonged laboratory processes involve greater risk of complications and possibly adverse events for the recipient, and so the need for control is correspondingly greater. To minimize the associate risks of cell manufacturing adhering to international quality standards is critical. Current good tissue practice (cGTP) and current good manufacturing practice (cGMP) are examples of general standards that draw a baseline for cell manufacturing facilities. In recent years, stem cell researches have found great public interest in Iran and different cell therapy projects have been started in country. In this review we described the role of our tissue banking experiences in establishing a new cGMP cell manufacturing facility. The authors concluded that, tissue banks and tissue banking experts can broaden their roles from preparing tissue grafts to manufacturing cell and tissue engineered products for translational researches and phase I clinical trials. Also they can collaborate with cell processing laboratories to develop SOPs, implement quality management system, and design cGMP facilities.

  9. Setting up a microneurosurgical skull base lab: technical and operational considerations.

    PubMed

    Salma, Asem; Chow, Andrew; Ammirati, Mario

    2011-07-01

    Microneurosurgical cadaveric dissections have become popular due to their usefulness in obtaining a working knowledge of the microneurosurgical anatomy in a controlled environment. This same controlled environment is also conducive to experiment with new surgical approaches. These factors have increased the number of microneurosurgical anatomic laboratories. Despite the increase in microneurosurgical laboratories, there is very little literature regarding the logistics of starting and maintaining a new neurosurgical laboratory. The aim of this paper is to provide a general road map and basic guidelines in starting and running a microneurosurgical dissection laboratory. The information in this paper is based on a review of the literature and on the experience we gained in organizing and managing the Dardinger Microneurosurgical Skull Base Laboratory at The Ohio State University.

  10. Case Study: Setting up and Running a Production Linux Cluster at Pacific Northwest National Laboratory

    SciTech Connect

    Skouson, Gary B.; Braby, Ryan L.

    2001-05-02

    With the low price and increasing performance of commodity computer hardware, it is important to study the viability of using clusters of relatively inexpensive computers to produce a stable system, capable of the current demands for high performance massively parallel computing. A 192-processor cluster was installed to test and develop methods that would make the PC cluster a workable alternative to using other commercial systems for use in scientific research. By comparing PC clusters with the cluster systems sold commercially, it became apparent that the tools to manage the PC cluster as a single system were not as robust or as well integrated as in many commercial systems. This paper is focused on the problems encountered and solutions used to stabilize this cluster for both production and development use. This included the use of extra hardware such as remote power control units and multi-port adapters to provide remote access to both the system console and system power. A Giganet cLAN fabric was also used to provide a high-speed, low-latency interconnect. Software solutions were used for resource management, job scheduling and accounting, parallel filesystems, remote network installation and system monitoring. Although there are still some tools missing for debugging hardware problems, the PC cluster continues to be very stable and useful for users.

  11. U.S. Judge's Ruling Sets Up New Battle over Care of Lab Animals.

    ERIC Educational Resources Information Center

    Burd, Stephen

    1993-01-01

    A federal court decision overturning federal regulations requiring research institutions to present plans for care and use of laboratory animals has renewed debate over laboratory animal welfare. University scientists fear new, stricter Department of Agriculture regulations will result. (MSE)

  12. Using Video Streaming: Setting Up a Cheap System for Distributing Information to Teachers and Students

    ERIC Educational Resources Information Center

    McNeal, Thomas, Jr.; Kearns, Landon

    2005-01-01

    Video streaming can be a very useful tool for educators. It is now possible for a school?s technical specialist or classroom teacher to create a streaming server with tools that are available in many classrooms. In this article we describe how we created our video streamer using free software, older computers, and borrowed hardware. The system…

  13. Setting up an ethics of ecosystem research structure based on the precautionary principle.

    PubMed

    Farmer, Michael C

    2013-01-01

    Ethical practices in ecological field research differ from those in laboratory research in more than the technical setting and the important distinction between population-level and individual-based concerns. The number of stakeholders affected by the conduct of field research is far larger; private landholders, public water utilities, public land managers, local industries, and communities large and small are only some of those who may be impacted. As research review boards move to establish specific ethical practices for field biologists, the process of identifying appropriate standards will affect the degree to which research will ultimately be disrupted. Standards that lead to research protocols that alienate key interests are not likely to be sustainable. Already, standards that have conflicted with the primary values of a key interest have resulted in disruptions to research and scientific progress. One way to manage this problem of deeply competing interests is to avoid the deepest offenses to any relevant interest group in the design of a proposed study. This is an application of the precautionary principle and is likely to generate a more sustainable balance among competing interests. Unfortunately, this process is also likely to be a never-ending, consensus-seeking process. Fortunately, scientists can have enormous influence on the process if they choose to engage in it early. If scientists use their expertise to function as honest brokers among affected interests, their own interest in scientific research progress is likely to be better met.

  14. Trying to set up the flavanolic phases during grape seed ripening: A spectral and chemical approach.

    PubMed

    Quijada-Morín, Natalia; García-Estévez, Ignacio; Nogales-Bueno, Julio; Rodríguez-Pulido, Francisco J; Heredia, Francisco J; Rivas-Gonzalo, Julián C; Escribano-Bailón, M Teresa; Hernández-Hierro, José Miguel

    2016-11-01

    Grape seeds were collected in ten different dates and classified in seven groups according to their individual hyperspectral imaging characteristics. Proanthocyanidin composition was studied using HPLC-MS for oligomers and acid catalyzed cleavage for polymers characterization. The combination of both analysis provided a complete description of the flavanols. Chemometric analysis was performed to summarize the analytical results. None of the considered variables presented statistical differences among all groups. From one to five groups were found for each variable, while three was the most frequent value, consequently three putative stages might be considered the real number of different analytical stages since it is the number of statistically significant groups for the majority of the compounds. This classification could be considered as the first step to optimize the use of seeds in winemaking to minimize the gap between sugar and phenolic maturities, consequence of the global climate change, mainly observed in warm climate. PMID:27591650

  15. Left-handed cardiac surgery: tips from set up to closure for trainees and their trainers.

    PubMed

    Burdett, Clare; Dunning, Joel; Goodwin, Andrew; Theakston, Maureen; Kendall, Simon

    2016-09-01

    There are certain obstacles which left-handed surgeons can face when training but these are not necessary and often perpetuated by a lack of knowledge. Most have been encountered and overcome at some point but unless recorded and disseminated they will have to be resolved repeatedly by each trainee and their trainers. This article highlights difficulties that the left-hander may encounter in cardiac surgery and gives practical operative advice for both trainees and their trainers to help overcome them.

  16. Experimental set up of a magnetoelectric measuring system operating at different temperatures

    NASA Astrophysics Data System (ADS)

    Gil, K.; Gil, J.; Cruz, B.; Ramirez, A.; Medina, M.; Torres, J.

    2016-02-01

    The magnetoelectric effect is the phenomenon whereby through a magnetic stimulation can be produced an electrical response or vice versa. We implement a magnetoelectric voltage measuring device through the dynamic method for a different range of temperatures. The system was split into an electric set and an instrumentation and control set. Design and element selection criteria that the experimenter must take into account are presented, with special emphasis in the design of the sample holder, which is the fundamental component that differentiates the system operating at high temperature and the one operating at room temperature. The experimental equipment consists of an electromagnet with DC magnetic flux density (B) in a range of (0.0 to 1.6) KOe, a Helmholtz coil which operates with a sinusoidal B between (0.0 and 0.016) KOe and a PT100 temperature sensor. A tubular heating resistance, a Checkman temperature control and an SSR 40A were used for controlling the temperature. As an application of the system, the transverse and longitudinal magnetoelectric coefficient was measured for a thin film of BiFeO3 at room temperature and 307K. It was observed that the behaviour of the longitudinal and transverse magnetoelectric coefficient matches the reported value and decreased with increasing temperature.

  17. Districts Weigh Benefits and Drawbacks of Setting Up Student E-Mail Accounts

    ERIC Educational Resources Information Center

    Ash, Katie

    2008-01-01

    Some school districts hoping to improve communication and student engagement in learning are taking a step many educators still view warily: providing students with their own e-mail accounts. However, making e-mail a regular part of students' school lives raises a host of concerns about inappropriate use. In addition, many teachers doubt that the…

  18. Setting Up a Grid-CERT: Experiences of an Academic CSIRT

    ERIC Educational Resources Information Center

    Moller, Klaus

    2007-01-01

    Purpose: Grid computing has often been heralded as the next logical step after the worldwide web. Users of grids can access dynamic resources such as computer storage and use the computing resources of computers under the umbrella of a virtual organisation. Although grid computing is often compared to the worldwide web, it is vastly more complex…

  19. Exact diagonalization: the Bose-Hubbard model as an example

    NASA Astrophysics Data System (ADS)

    Zhang, J. M.; Dong, R. X.

    2010-05-01

    We take the Bose-Hubbard model to illustrate exact diagonalization techniques in a pedagogical way. We follow the route of first generating all the basis vectors, then setting up the Hamiltonian matrix with respect to this basis and finally using the Lanczos algorithm to solve low lying eigenstates and eigenvalues. Emphasis is placed on how to enumerate all the basis vectors and how to use the hashing trick to set up the Hamiltonian matrix or matrices corresponding to other quantities. Although our route is not necessarily the most efficient one in practice, the techniques and ideas introduced are quite general and may find use in many other problems.

  20. Model simulations of dense bottom currents in the Western Baltic Sea

    NASA Astrophysics Data System (ADS)

    Burchard, Hans; Janssen, Frank; Bolding, Karsten; Umlauf, Lars; Rennau, Hannes

    2009-01-01

    Only recently, medium intensity inflow events into the Baltic Sea have gained more awareness because of their potential to ventilate intermediate layers in the Southern Baltic Sea basins. With the present high-resolution model study of the Western Baltic Sea a first attempt is made to obtain model based realistic estimates of turbulent mixing in this area where dense bottom currents resulting from medium intensity inflow events are weakened by turbulent entrainment. The numerical model simulation which is carried out using the General Estuarine Transport Model (GETM) during nine months in 2003 and 2004 is first validated by means of three automatic stations at the Drogden and Darss Sills and in the Arkona Sea. In order to obtain good agreement between observations and model results, the 0.5×0.5 nautical mile bathymetry had to be adjusted in order to account for the fact that even at that scale many relevant topographic features are not resolved. Current velocity, salinity and turbulence observations during a medium intensity inflow event through the Øresund are then compared to the model results. Given the general problems of point to point comparisons between observations and model simulations, the agreement is fairly good with the characteristic features of the inflow event well represented by the model simulations. Two different bulk measures for mixing activity are then introduced, the vertically integrated decay of salinity variance, which is equal to the production of micro-scale salinity variance, and the vertically integrated turbulent salt flux, which is related to an increase of potential energy due to vertical mixing of stably stratified flow. Both measures give qualitatively similar results and identify the Drogden and Darss Sills as well as the Bornholm Channel as mixing hot spots. Further regions of strong mixing are the dense bottom current pathways from these sills into the Arkona Sea, areas around Kriegers Flak (a shoal in the western Arkona Sea

  1. A Cost Free Counseling Model for High Risk Elementary Students.

    ERIC Educational Resources Information Center

    Albaum, Jean Stirling

    A cost-free counseling model was developed to meet the changing needs of elementary school students in a small college city in California. A training program for graduate students was set up within the public school setting and was clinically supervised. Marriage, Family, and Child Counselor and Licensed Educational Psychologist internships were…

  2. Neuron model-free PID control

    NASA Astrophysics Data System (ADS)

    Wang, Ning; Zhang, Li; Wang, Shuqing

    2001-09-01

    Based on the neuron model and learning strategy, the neuron intelligent PID control system is set up in this paper. The neuron model-free PID control method is posed. The simulation tests with an example of a hydraulic turbine generator unit are made. The result show that god control performances are obtained. This new intelligent controller is very simple and has very strong adaptability and robustness. It can be used directly in practice.

  3. Development of a novel in vitro onychomycosis model for the evaluation of topical antifungal activity.

    PubMed

    Sleven, Reindert; Lanckacker, Ellen; Boulet, Gaëlle; Delputte, Peter; Maes, Louis; Cos, Paul

    2015-05-01

    A novel in vitro onychomycosis model was developed to easily predict the topical activity potential of novel antifungal drugs. The model encompasses drug activity and diffusion through bovine hoof slices in a single experimental set-up. Results correspond well with the antifungal susceptibility assay and Franz cell diffusion test.

  4. LDV Measurements in an Annular Combustor Model

    NASA Technical Reports Server (NTRS)

    Barron, Dean A.

    1996-01-01

    This thesis covers the design and setup of a laser doppler velocimeter (LDV) system used to take velocity measurements in an annular combustor model. The annular combustor model is of contemporary design using 60 degree flat vane swirlers, producing a strong recirculation zone. Detailed measurements are taken of the swirler inlet air flow and of the downstream enclosed swirling flow. The laser system used is a two color, two component system set up in forward scatter. Detailed are some of the special considerations needed for LDV use in the confined turbulent flow of the combustor model. LDV measurements in a single swirler rig indicated that the flow changes radically in the first duct height. After this, a flow profile is set up and remains constant in shape. The magnitude of the velocities gradually decays due to viscous damping.

  5. Flow characteristics in a crowded transport model

    NASA Astrophysics Data System (ADS)

    Burger, Martin; Pietschmann, Jan-Frederik

    2016-11-01

    The aim of this paper is to discuss the appropriate modelling of in- and outflow boundary conditions for nonlinear drift-diffusion models for the transport of particles including size exclusion and their effect on the behaviour of solutions. We use a derivation from a microscopic asymmetric exclusion process and its extension to particles entering or leaving on the boundaries. This leads to specific Robin-type boundary conditions for inflow and outflow, respectively. For the stationary equation we prove the existence of solutions in a suitable set-up. Moreover, we investigate the flow characteristics for a small diffusion parameter \\varepsilon , which yields the occurrence of a maximal current phase in addition to well-known one-sided boundary layer effects for linear drift-diffusion problems. In a 1D set-up we provide rigorous estimates in terms of ε, which confirm three different phases. Finally, we derive a numerical approach to solve the problem also in multiple dimensions.

  6. Advocating for School Psychologists in Response to the APA's Proposed "Model Act for State Licensure of Psychologists"

    ERIC Educational Resources Information Center

    Skalski, Anastasia Kalamaros

    2009-01-01

    On March 6, 2009, the APA Model Licensure Act Task Force released its second draft of the policy document known as the proposed "Model Act for State Licensure of Psychologists". This policy document serves as guidance to state legislatures for how they should set up their psychology licensing laws. The general expectations promoted in the model…

  7. Modeling, system identification, and control of ASTREX

    NASA Technical Reports Server (NTRS)

    Abhyankar, Nandu S.; Ramakrishnan, J.; Byun, K. W.; Das, A.; Cossey, Derek F.; Berg, J.

    1993-01-01

    The modeling, system identification and controller design aspects of the ASTREX precision space structure are presented in this work. Modeling of ASTREX is performed using NASTRAN, TREETOPS and I-DEAS. The models generated range from simple linear time-invariant models to nonlinear models used for large angle simulations. Identification in both the time and frequency domains are presented. The experimental set up and the results from the identification experiments are included. Finally, controller design for ASTREX is presented. Simulation results using this optimal controller demonstrate the controller performance. Finally the future directions and plans for the facility are addressed.

  8. Modeling, system identification, and control of ASTREX

    NASA Astrophysics Data System (ADS)

    Abhyankar, Nandu S.; Ramakrishnan, J.; Byun, K. W.; Das, A.; Cossey, Derek F.; Berg, J.

    1993-02-01

    The modeling, system identification and controller design aspects of the ASTREX precision space structure are presented in this work. Modeling of ASTREX is performed using NASTRAN, TREETOPS and I-DEAS. The models generated range from simple linear time-invariant models to nonlinear models used for large angle simulations. Identification in both the time and frequency domains are presented. The experimental set up and the results from the identification experiments are included. Finally, controller design for ASTREX is presented. Simulation results using this optimal controller demonstrate the controller performance. Finally the future directions and plans for the facility are addressed.

  9. Development of an Interactive Computer-Based Learning Strategy to Assist in Teaching Water Quality Modelling

    ERIC Educational Resources Information Center

    Zigic, Sasha; Lemckert, Charles J.

    2007-01-01

    The following paper presents a computer-based learning strategy to assist in introducing and teaching water quality modelling to undergraduate civil engineering students. As part of the learning strategy, an interactive computer-based instructional (CBI) aid was specifically developed to assist students to set up, run and analyse the output from a…

  10. The Modeling Analysis of Huangshan Tourism Data

    NASA Astrophysics Data System (ADS)

    Hu, Shanfeng; Yan, Xinhu; Zhu, Hongbing

    2016-06-01

    Tourism is the major industry in Huangshan city. This paper analyzes time series of tourism data to Huangshan from 2000 to 2013. The Yearly data set comprises the total arrivals of tourists, total income, Urban Resident Disposable Income Per Capital and Net Income Per Peasant. A mathematical model which is based on the binomial approximation and inverse quadratic radial basis function (RBF) is set up to model the tourist arrivals. The total income and urban resident disposable income per capital and net income per peasant are also modeled. It is shown that the established mathematical model can be used to forecast some tourism information and achieve a good management for Huangshan tourism.

  11. Numerical modelling of POC yearly dynamics in the southern Baltic under variable scenarios of nutrients, light and temperature

    NASA Astrophysics Data System (ADS)

    Dzierzbicka-Glowacka, L.; Kuliński, K.; Maciejewska, A.; Jakacki, J.; Pempkowiak, J.

    2011-03-01

    This paper presents various scenarios of the particulate organic carbon (POC) in the southern Baltic Sea. The study is based on a one-dimensional Particulate Organic Carbon model (1-D POC). Mathematically, the pelagic variables of 1-D POC model are described by a second-order partial differential equations of the diffusion type with biogeochemical sources and sinks. The POC concentration is determined as the sum of phytoplankton, zooplankton and dead organic matter (detritus) concentrations. The temporal changes in the phytoplankton biomass are caused by primary production, mortality, grazing by zooplankton and sinking. The zooplankton biomass is affected by ingestion, excretion, faecal production, mortality, and carnivorous grazing. The changes in the pelagic detritus concentration are determined by input of: dead phytoplankton and zooplankton, natural mortality of predators, faecal pellets, and sinks: sedimentation, zooplankton grazing and biochemical decomposition. The 1-D POC model was used to simulate temporal dynamics of POC in the southern Baltic Sea (Gdansk Deep, Bornholm Deep and Gotland Deep) under scenarios characterized by different temperature, nutrients and light. Daily, monthly, seasonal and annual variabilities of POC in the upper water layer are presented for the different scenarios. The starting-point of the numerical simulations was assumed as average values of the investigated pelagic variables for 1965-1998 period. Two- to three-fold increases of POC concentrations in late spring were revealed as well as the shift towards postponed maximum POC concentration. It is speculated that, due to POC increase, oxygenation of under-halocline water layer will decrease, while supply of food to organisms from higher trophic level should increase.

  12. On the Dual Nature of the Functional Discourse Grammar Model: Context, the Language System/Language Use Distinction, and Indexical Reference in Discourse

    ERIC Educational Resources Information Center

    Cornish, Francis

    2013-01-01

    The Functional Discourse Grammar model has a twofold objective: on the one hand, to provide a descriptively, psychologically and pragmatically adequate account of the forms made available by a typologically diverse range of languages; and on the other, to provide a model of language which is set up to reflect, at one remove, certain of the stages…

  13. Quantitative comparisons of analogue models of brittle wedge dynamics

    NASA Astrophysics Data System (ADS)

    Schreurs, Guido

    2010-05-01

    Analogue model experiments are widely used to gain insights into the evolution of geological structures. In this study, we present a direct comparison of experimental results of 14 analogue modelling laboratories using prescribed set-ups. A quantitative analysis of the results will document the variability among models and will allow an appraisal of reproducibility and limits of interpretation. This has direct implications for comparisons between structures in analogue models and natural field examples. All laboratories used the same frictional analogue materials (quartz and corundum sand) and prescribed model-building techniques (sieving and levelling). Although each laboratory used its own experimental apparatus, the same type of self-adhesive foil was used to cover the base and all the walls of the experimental apparatus in order to guarantee identical boundary conditions (i.e. identical shear stresses at the base and walls). Three experimental set-ups using only brittle frictional materials were examined. In each of the three set-ups the model was shortened by a vertical wall, which moved with respect to the fixed base and the three remaining sidewalls. The minimum width of the model (dimension parallel to mobile wall) was also prescribed. In the first experimental set-up, a quartz sand wedge with a surface slope of ˜20° was pushed by a mobile wall. All models conformed to the critical taper theory, maintained a stable surface slope and did not show internal deformation. In the next two experimental set-ups, a horizontal sand pack consisting of alternating quartz sand and corundum sand layers was shortened from one side by the mobile wall. In one of the set-ups a thin rigid sheet covered part of the model base and was attached to the mobile wall (i.e. a basal velocity discontinuity distant from the mobile wall). In the other set-up a basal rigid sheet was absent and the basal velocity discontinuity was located at the mobile wall. In both types of experiments

  14. One Small Step for Creo Modelers, One Giant Leap for "Grey Beards": Using MBD Methodologies to Launch Astronauts and Hardware to Near-Earth Objects such as Asteroids, the Moon and Mars

    NASA Technical Reports Server (NTRS)

    Jones, Corey; LaPha, Steven

    2013-01-01

    This presentation will focus on the modernization of design and engineering practices through the use of Model Based Definition methodology. By gathering important engineering data into one 3D digital data set, applying model annotations, and setting up model view states directly in the 3D CAD model, model-specific information can be published to Windchill and CreoView for use during the Design Review Process. This presentation will describe the methods that have been incorporated into the modeling.

  15. Study of boron detection limit using the in-air PIGE set-up at LAMFI-USP

    NASA Astrophysics Data System (ADS)

    Moro, M. V.; Silva, T. F.; Trindade, G. F.; Added, N.; Tabacniks, M. H.

    2014-11-01

    The quantification of small amounts of boron in materials is of extreme importance in different areas of materials science. Boron is an important contaminant and also a silicon dopant in the semiconductor industry. Boron is also extensively used in nuclear power plants, either for neutron shielding or for safety control and boron is an essential nutrient for life, either vegetable or animal. The production of silicon solar cells, by refining metallurgical-grade silicon (MG-Si) requires the control and reduction of several silicon contaminants to very low concentration levels. Boron is one of the contaminants of solar-grade silicon (SG-Si) that must be controlled and quantified at sub-ppm levels. In the metallurgical purification, boron quantification is usually made by Inductive Coupled Plasma Mass Spectrometry, (ICP-MS) but the results need to be verified by an independent analytical method. In this work we present the results of the analysis of silicon samples by Particle Induced Gamma-Ray Emission (PIGE) aiming the quantification of low concentrations of boron. PIGE analysis was carried out using the in-air external beam line of the Laboratory for Materials Analysis with Ion Beans (LAMFI-USP) by the 10B ( p ,αγ(7Be nuclear reaction, and measuring the 429 keV γ-ray. The in-air PIGE measurements at LAMFI have a quantification limit of the order of 1016 at/cm2.

  16. SU-E-I-58: Experiences in Setting Up An Online Fluoroscopy Tracking System in a Large Healthcare System

    SciTech Connect

    Fisher, R; Wunderle, K; Lingenfelter, M

    2015-06-15

    Purpose: Transitioning from a paper based to an online system for tracking fluoroscopic case information required by state regulation and to conform to NCRP patient dose tracking suggestions. Methods: State regulations require documentation of operator, equipment, and some metric of tube output for fluoroscopy exams. This information was previously collected in paper logs, which was cumbersome and inefficient for the large number of fluoroscopic units across multiple locations within the system. The “tech notes” feature within Siemens’ Syngo workflow RIS was utilized to create an entry form for technologists to input case information, which was sent to a third party vendor for archiving and display though an online web based portal. Results: Over 55k cases were logged in the first year of implementation, with approximately 6,500 cases per month once fully online. A system was built for area managers to oversee and correct data, which has increased the accuracy of inputted values. A high-dose report was built to automatically send notifications when patients exceed trigger levels. In addition to meeting regulatory requirements, the new system allows for larger scale QC in fluoroscopic cases by allowing comparison of data from specific procedures, locations, equipment, and operators so that instances that fall outside of reference levels can be identified for further evaluation. The system has also drastically improved identification of operators without documented equipment specific training. Conclusion: The transition to online fluoroscopy logs has improved efficiency in meeting state regulatory requirements as well as allowed for identification of particular procedures, equipment, and operators in need of additional attention in order to optimize patient and personnel doses, while high dose alerts improve patient care and follow up. Future efforts are focused on incorporating case information from outside of radiology, as well as on automating processes for increased efficiencies.

  17. Assessment of drinking water radioactivity content by liquid scintillation counting: set up of high sensitivity and emergency procedures.

    PubMed

    Rusconi, R; Azzellino, A; Bellinzona, S; Forte, M; Gallini, R; Sgorbati, G

    2004-05-01

    In our institute, different procedures have been developed to measure the radioactivity content of drinking water both in normal and in emergency situations, such as those arising from accidental and terrorist events. A single radiometric technique, namely low level liquid scintillation counting (LSC), has been used. In emergency situations a gross activity screening is carried out without any sample treatment by a single and quick liquid scintillation counting. Alpha and beta activities can be measured in more than one hundred samples per day with sensitivities of a few Bq/L. Higher sensitivity gross alpha and beta, uranium and radium measurements can be performed on water samples after specific sample treatments. The sequential method proposed is designed in such a way that the same water sample can be used in all the stages, with slight modifications. This sequential procedure was applied in a survey of the Lombardia district. At first tap waters of the 13 largest towns were examined, then a more detailed monitoring was carried out in the surroundings of Milano and Lodi towns. The high sensitivity method for the determination of uranium isotopes was used to check the presence of depleted uranium in Lake Garda. Reduced equipment requirements and relative readiness of radiochemical procedures make LSC an attractive technique which can also be applied by laboratories lacking specific radiochemistry facilities and experience.

  18. Designing an optical set-up of differential laser triangulation for oil film thickness measurement on water.

    PubMed

    Ge, Baozhene; Sun, Jingbin; Liu, Pengcheng; Lü, Qieni; Wu, Di

    2013-01-01

    Based on the differential laser triangulation principle, an optical system configuration for measuring the oil film thickness on water is designed and developed. A semiconductor laser of 650 nm wavelength with the maximum power of 5 mW is used as a light source, the magnification of the imaging system is 1.4; the range of the measurement is 0.1 mm-10 mm; the resolution is 2.3 μm and the measurement accuracy is 10 μm theoretically. Experiments are conducted with block gauges and feeler gauges, and the experimental results, with absolute error less than ±25 μm and the maximal measurable thickness 12 mm, indicate that this system presented in this paper can fulfill high accuracy.

  19. On-line diagnostics of washing machines: design issues for the optimization of the measurement set-up

    NASA Astrophysics Data System (ADS)

    Agostinelli, G.; Paone, N.; Cristalli, C.; Torcianti, B.

    2008-06-01

    This paper discusses some of the relevant aspects that a designer of an on-line test station for washing machine diagnostics based on a single-point laser Doppler vibrometer should consider. In particular, the paper presents a series of experiments useful to answer the two following questions: a) Where to locate the measurement point? b) Does the test need to be done with an external load to be inserted into the rotating drum? Tests have been done on a "good" washing machine and on a machine exhibiting the most frequent defects to be detected in production line. The study of the Operating Deflection Shapes (ODS) of the machine has been used to determine the best area of the machine cabinet where to position the single point laser vibrometer for on-line diagnostics. In order to support the decision whether or not to employ an artificial unbalance load inserted into the drum during the dynamic test, measurements have been repeated with and without load. Results have been analysed to highlight pros and cons of the use of an external load.

  20. Spectroscopy of transfermium nuclei using the GABRIELA set up at the focal plane of the VASSILISSA recoil separator

    SciTech Connect

    Hauschild, K.; Lopez-Martens, A.; Dorvaux, O.; Piot, J.; Curien, D.; Gall, B.; Yeremin, A. V.; Chelnokov, M. L.; Chepigin, V. I.; Isaev, A. V.; Izosimov, I. N.; Kabachenko, A. P.; Katrasev, D. E.; Kuznetsov, A. N.; Malyshev, O. N.; Popeko, A. G.; Sokol, E. A.; Svirikhin, A. I.; Wiborg-Hagen, T.; Nyhus, H. T

    2010-06-01

    An IN2P3-JINR collaboration has launched a project called GABRIELA at the Flerov Laboratory for Nuclear Reactions (FLNR) within the Joint Institute for Nuclear Research (JINR) in Dubna (Russia). The goal of the project is to perform gamma-ray and internal conversion electron spectroscopy of heavy nuclei produced in fusion-evaporation reactions and transported to the focal plane of the recoil separator VASSILISSA. During five experimental campaigns of GABRIELA, the detection system has gained in sensitivity and new spectroscopic information has been obtained for {sup 249}Fm, {sup 251}Fm, {sup 253}No and {sup 255}Lr. In this contribution new results for {sup 253}No will be discussed.

  1. Utilization of Medicines Available at Home by General Population of Rural and Urban Set Up of Western India

    PubMed Central

    Ganguly, Barna

    2016-01-01

    Introduction In India, medicines are procured with prescription or without prescription by patients, which are kept at home and often are utilized in inappropriate manner. It may remain unused, get expired or may be repeated in the way of self medication. So there remains an increase chance of self-medication compared to prescribed drugs. Aim This study was aimed to explore the utilization pattern of medicines available at home with special attention to the types of medicine (with or without prescription) and their appropriate utilization (dosage compliance) and intended self-medication. Materials and Methods A cross-sectional study was conducted in Anand district of Gujarat, India during the year 2012- 2014 after Human Research Ethics Committee (HREC) approval. Data were collected from 800 houses, 400 each from urban and rural areas and then analysed for the details of medicines available in the house as: (i) number of homes having medicines; (ii) number of formulations with and without prescriptions; (iii) number of formulations with package inserts & expired formulations; (iv) Dosage forms of medicines; (v) pharmacological class wise distribution of medicines; (vi) status of the medicine use whether for current use, future use or leftover; and (vii) Appropriateness of medicines with and without prescription in relation to dose and duration of treatment. Results Medicines were available in 93.75% houses. More medicine formulations (16.76%) were found without prescription in urban area than in rural (11.82%). Highest number of dosage forms found, were that of tablets (62%). Among the prescribed medicines, majority of medicines were from cardiovascular disease (19.88%) and from without prescription medicines, Non-Steroidal Antiinflammatory Drugs (NSAIDs) were the major group available at houses (35.13%). The leftover medicines with prescription were 20.39% and without prescription medicines were 13.37%. Appropriate dose and duration of medicines were followed more significantly by urban people than the rural. Only 2.91% medicines were found along with package inserts and 2.94% crossed the expiry dates. Conclusion The evaluation of utilization of medicines, in urban and rural population describes high drug storage, higher leftover medicines and inappropriate use of medicines and many self medicated by patients which suggests the need to educate the patients about proper and rational use of medicines. PMID:27656460

  2. Public Relations Guide. Featuring PR Tools, PR Techniques, How To Set Up a PR Seminar. Revised Edition.

    ERIC Educational Resources Information Center

    Procter and Gamble Educational Services, Cincinnati, OH.

    The goal of this guide is two-fold: (1) to equip readers with practical guidelines for establishing communications plans and making those plans work; and (2) to develop information for implementing a public relations seminar targeted at designing workshops that reach a broad segment of members. Five topics are addressed: (1) the basic public…

  3. Radiation Monitoring using an Unmanned Helicopter in the Evacuation Zone Set up by the Fukushima Daiichi NPP Accident.

    NASA Astrophysics Data System (ADS)

    Torii, Tatsuo; Sanada, Yukihisa; Nishizawa, Yukiyasu; Kondo, Atsuya; Shoji, Yasunori; ikeda, Kazutaka

    2013-04-01

    By the nuclear accident of the Fukushima Daiichi Nuclear Power Plant (NPP) caused by the East Japan earthquake and the following tsunami occurred on March 11, 2011, a large amount of radioactive materials was released from the NPP. In recent years, technologies for an unmanned helicopter have been developed and applied to natural disasters. In expectation of the application of the unmanned helicopter to airborne radiation monitoring, we had developed a radiation monitoring system using an autonomous unmanned helicopter (AUH). Then, we measured the ambient dose-rate at the height of 1-m above the ground and the soil deposition of radioactive cesium (Cs-134, Cs-137) by using the AUH system in the evacuation zone of residents around the NPP. Here, we report on the measurement technique and the result. As a result measured around a river at 10-km away from the NPP, high contaminated areas compared with the circumstance are detected along the dry riverbed. It was seemed that it had flowed along the river from highly contaminated areas in the upper stream.

  4. Set-up and application of an analytical approach for the quality control of purified colostrum as food supplement.

    PubMed

    Altomare, Alessandra; Regazzoni, Luca; Parra, Ximena Maria Paredes; Selmin, Francesca; Rumio, Cristiano; Carini, Marina; Aldini, Giancarlo

    2016-08-15

    A validated analytical procedure is here described for the quality control of the protein fraction of purified bovine colostrum used in food supplements. The proposed procedure starts with 1D and 2D-gel electrophoresis. The sample is then separated into two fractions by protein G affinity chromatography: the IgG enriched and the IgG depleted fraction (IgG-d). A size exclusion chromatography coupled to UV is then applied to the IgG and IgG-d fractions for the quantitative analysis of IgG and IgM, respectively. The IgG-d fraction is then analysed by HPLC-MS analysis for the quantitative analysis of β-lactoglobulins and α-lactoalbumin. The next step is to quantitatively measure a set of bioactive proteins selected from the bovine colostrum data bank on the basis of their claimed health benefits. The enzymatic activities of lactoperoxidase and xanthine dehydrogenase/oxidase are then tested as an index of protein functionality. PMID:27341426

  5. Effect of Patient Set-up and Respiration motion on Defining Biological Targets for Image-Guided Targeted Radiotherapy

    NASA Astrophysics Data System (ADS)

    McCall, Keisha C.

    Identification and monitoring of sub-tumor targets will be a critical step for optimal design and evaluation of cancer therapies in general and biologically targeted radiotherapy (dose-painting) in particular. Quantitative PET imaging may be an important tool for these applications. Currently radiotherapy planning accounts for tumor motion by applying geometric margins. These margins create a motion envelope to encompass the most probable positions of the tumor, while also maintaining the appropriate tumor control and normal tissue complication probabilities. This motion envelope is effective for uniform dose prescriptions where the therapeutic dose is conformed to the external margins of the tumor. However, much research is needed to establish the equivalent margins for non-uniform fields, where multiple biological targets are present and each target is prescribed its own dose level. Additionally, the size of the biological targets and close proximity make it impractical to apply planning margins on the sub-tumor level. Also, the extent of high dose regions must be limited to avoid excessive dose to the surrounding tissue. As such, this research project is an investigation of the uncertainty within quantitative PET images of moving and displaced dose-painting targets, and an investigation of the residual errors that remain after motion management. This included characterization of the changes in PET voxel-values as objects are moved relative to the discrete sampling interval of PET imaging systems (SPECIFIC AIM 1). Additionally, the repeatability of PET distributions and the delineating dose-painting targets were measured (SPECIFIC AIM 2). The effect of imaging uncertainty on the dose distributions designed using these images (SPECIFIC AIM 3) has also been investigated. This project also included analysis of methods to minimize motion during PET imaging and reduce the dosimetric impact of motion/position-induced imaging uncertainty (SPECIFIC AIM 4).

  6. Modulated heterodyne light scattering set-up for measuring long relaxation time at small and wide angle

    SciTech Connect

    Leone, Nancy; Villari, Valentina; Micali, Norberto

    2012-08-15

    We present a simple, compact, and versatile experimental setup working in the heterodyne detection mode with modulation of the reference beam. The system is implemented with a collection optics based on a unimodal optical fiber coupler. This choice allows the heterodyne to be used in a wide range of scattering angles, even for very small ones, without losing the optical beating. The apparatus can be successfully used to study translational diffusive dynamics of dispersed particles at scattering angles smaller than 5 Degree-Sign and it is suitable for exploring slow relaxation processes in sub-Hertz frequency domain, for example, in glass-forming systems. It is also possible to measure the electrophoretic mobility by applying an electric field into a charged particles solution.

  7. SETTING UP TRIAGE SERVICES IN THE EMERGENCY DEPARTMENT: EXPERIENCE FROM A TERTIARY CARE INSTITUTE OF PAKISTAN. A JOURNEY TOWARD EXCELLENCE.

    PubMed

    Khursheed, Munawar; Fayyaz, Jabeen; Jamil, Ahsan

    2015-01-01

    The history of triage started from the French battle field for prioritizing patients. Emergency triage was started in early 1950's in USA in order to treat the sickest first. It has now become an integral component of all emergency departments (ED). The basic aim of triage is not only to sort out patients according to the criticality of their illness, but it also serves to streamline the patient flow. This will ultimately enable the ED physician to provide right management at the right time to the right patient in the available resources. In turn has a positive impact in reducing the ED overcrowding. The history of triage at AKUH-ED dated back in 2000. In the beginning physicians and nurse both were assigned to triage desk where they use to sort out the patient according to presenting complaints. At that time the documentation was manual with locally developed triage priorities. With the expansion of ED in 2008, responsibility of triage was shifted to nursing services. Triage policy was established and implemented. Specific triage protocols were developed for guidance and uniformity of care. Manual recording system was replaced by computerized triage data entry software. Enabling the department to monitor patient quality care indicators like total number of patients triaged, triage category, lag time reports and left without being seen by physicians. PMID:26721057

  8. Isocapnic hyperpnea with a portable device in Cystic Fibrosis: an agreement study between two different set-up modalities.

    PubMed

    Gambazza, Simone; Ceruti, Clara; Brivio, Anna; Piaggi, Giancarlo; Karapanagiotis, Solon; Colombo, Carla

    2015-10-01

    To evaluate the bias and precision of the respiratory muscle training device formulas to predict respiratory minute volume (RMV) and volume of the reservoir bag (BV) on a cohort of subjects with Cystic Fibrosis (CF). CF patients with available pulmonary function tests and maximal voluntary manoeuvres were included in the study. Vital capacity and maximal voluntary ventilation were extracted from subjects' records and then inserted to the manufacturer's formulas to obtain RMV and BV (measured setting). RMV and BV were compared according to standard and measured formulas in males and females. Sample was described and then processed using Bland-Altman analysis. Bland-Altman analysis for RMV revealed a bias and precision of 8.8 ± 29 L/min in males and 28.8 ± 16 L/min in females; 0.4 ± 0.5 L in males and 0.7 ± 0.4 L in females for BV. Concordance correlation coefficients for RMV were -0.03 in males and 0.02 in females; 0.22 in males and 0.03 in females for BV, reinforcing an unsatisfactory concordance between measured and manufacturer setting. This study shows considerable discrepancies between the two methods, making the degree of agreement not clinically acceptable. This might cause inappropriate setting and disservice to patients with CF. PMID:25348833

  9. Safe Cockroach Control: A Guide to Setting Up an Integrated Pest Management Program within a School System.

    ERIC Educational Resources Information Center

    Cowles, Kathleen Letcher; And Others

    Integrated Pest Management (IPM) is a decision-making approach to pest control that has been used successfully on farms, city parks, offices, homes, and schools. IPM programs help individuals decide when treatments are necessary, where treatment would be most helpful, and what combinations of tactics would be most effective, safe, and inexpensive…

  10. Comparing FTIR and RAPD techniques in the typing of C. albicans in a clinical set-up

    NASA Astrophysics Data System (ADS)

    Sandt, Christophe L.; Sockalingum, Ganesh D.; Toubas, Dominique; Aubert, Dominique; Lepan, Herve; Lepouse, Claire; Jaussaud, Maryse; Leon, Alain; Pinon, Jean-Michel; Manfait, Michel

    2002-03-01

    Candida albicans is an opportunistic pathogen, generally though to be of endogenous origin, with however reported outbreaks. Epidemilogy of C. albicans has been studied so far by genotypic methods mainly, including the classical RAPD analysis. Albeit powerful, genotypic techniques are expensive, time consuming and complex to implement. FTIR spectroscopy is simple, rapid, inexpensive and an increasingly used technique for the identification of microorganisms. As a phenotypic method, it provides rapid whole cells 'fingerprinting' using few consumables and can detect very subtle differences between strains of the same species. In this study, C. albicans strains isolated from 50 patients from six hospital units were collected and studied by FTIR spectroscopy and RAPD-PCR. Discrimination of strains was computed using classification algorithms on selected features of the spectral data. Results from 10 patients, for whom iterative sampling was possible, are presented and discussed. Emphasis was laid on the reproducibility of dat for strain-level identification. FTIR analysis shows that (a) the C. albicans spectra were different from one patient to another, (b) seven patients exhibit each a homogeneous group while three patients display each two groups of strains. RAPD-PCR and FTIR analyses correlate quite well showing that FTIR spectroscopy could be a potential epidemiological tool in the control of nosocomial fungal infections.

  11. SETTING UP TRIAGE SERVICES IN THE EMERGENCY DEPARTMENT: EXPERIENCE FROM A TERTIARY CARE INSTITUTE OF PAKISTAN. A JOURNEY TOWARD EXCELLENCE.

    PubMed

    Khursheed, Munawar; Fayyaz, Jabeen; Jamil, Ahsan

    2015-01-01

    The history of triage started from the French battle field for prioritizing patients. Emergency triage was started in early 1950's in USA in order to treat the sickest first. It has now become an integral component of all emergency departments (ED). The basic aim of triage is not only to sort out patients according to the criticality of their illness, but it also serves to streamline the patient flow. This will ultimately enable the ED physician to provide right management at the right time to the right patient in the available resources. In turn has a positive impact in reducing the ED overcrowding. The history of triage at AKUH-ED dated back in 2000. In the beginning physicians and nurse both were assigned to triage desk where they use to sort out the patient according to presenting complaints. At that time the documentation was manual with locally developed triage priorities. With the expansion of ED in 2008, responsibility of triage was shifted to nursing services. Triage policy was established and implemented. Specific triage protocols were developed for guidance and uniformity of care. Manual recording system was replaced by computerized triage data entry software. Enabling the department to monitor patient quality care indicators like total number of patients triaged, triage category, lag time reports and left without being seen by physicians.

  12. Investigation of Forming Strategies to Set up Mechanical Properties of Parts Made by Incremental Sheet Bulk Rolling

    NASA Astrophysics Data System (ADS)

    Plugge, B.; Schunck, S.; Kwiatkowski, L.; Brosius, A.; Tekkaya, A. E.

    2011-05-01

    Load-adapted parts with an increasing number of functions become more and more interesting in order to reduce the weight of all kinds of mechanical constructions. Such parts require varying mechanical properties and towards they are cost-expensive. One approach to reduce the costs is the application of cheap semi-finished parts. To process such parts, especially in thickness direction, bulk-forming operations are requested. This leads to high forming forces. A feasible approach to reduce the forces is the application of incremental forming techniques. In this paper an incremental rolling process is presented. The sequential order of forming operations during incremental rolling allows an individual adjustment of mechanical and the geometrical properties. In the presented study a sheet with a thickness of 2 mm made of mild steel is formed using a roller ball with a diameter of 13 mm. Main objective of the investigation is to manufacture parts with equal values for thickness but different values of the local surface hardness. The investigation is supported by Finite-Element-Analysis (FEA) to determine the distribution of the strains over the part's thickness. The results show that it is possible to manufacture parts with the same thickness and different surface hardness by applying different forming strategies. Keeping the entire process parameters constant but rolling the part alternating at both surfaces will result in a higher hardness on the surface in comparison to a one-sided rolling.

  13. Do-It-Yourself Guide to: A Land Use Seminar. Construction Plans, Use Guidelines and Set-Up Information.

    ERIC Educational Resources Information Center

    Buck, Harry L.

    The land use seminar described involves the use of 12 stations containing displays relating to land use. Each student is provided a data sheet and instructed to answer questions requiring the obtaining of data from the displays. Discussion questions are also included for later attention. The guide provides instructions for the construction of each…

  14. Employing injection-locked FP LDs to set up a hybrid CATV/MW/MMW WDM light wave transmission system.

    PubMed

    Lin, Chun-Yu; Lu, Hai-Han; Li, Chung-Yi; Wu, Po-Yi; Peng, Peng-Chun; Jhang, Tai-Wei; Lin, Che-Yu

    2014-07-01

    A hybrid cable television (CATV)/microwave (MW)/millimeter-wave (MMW) wavelength-division-multiplexing (WDM) light wave transmission system based on injection-locked Fabry-Perot laser diodes (FP LDs) is proposed and demonstrated. Different from conventional hybrid WDM light wave transmission systems, which need wavelength-selected distributed feedback laser diodes to support various services, the proposed systems employ injection-locked FP LDs to provide multiple applications. Over a 40 km single-mode fiber transport, impressive performances of carrier-to-noise ratio/composite second-order/composite triple-beat/bit error rate are obtained for 550 MHz CATV/20 GHz MW/40 GHz MMW/60 GHz MMW signal transmissions. Such a hybrid WDM light wave transmission system would be attractive for fiber links to provide broadband integrated services.

  15. A new set-up for the simultaneous measurement of neutron-induced capture and fission reactions

    SciTech Connect

    Guerrero, C.; Berthoumieux, E.; Cano-Ott, D.; Gunsing, F.; Andriamonje, S.

    2011-07-01

    The measurement of the capture cross section of fissile elements, of upmost importance for the design of innovative nuclear reactors and the management of nuclear waste, involves particular difficulties related to the {gamma}-ray background produced in the fission reactions. These difficulties are the reason why five out of the six actinide {sigma}(n,{gamma}) measurements in the NEA High Request Priority List are fissile isotopes. At n-TOF we have combined the Total Absorption Calorimeter capture detector with a set of three {sup 235}U loaded MicroMegas fission detectors for measuring simultaneously the two reactions: capture and fission. In a first test measurement we have succeeded in measuring simultaneously with high efficiency the {sup 235}U capture and fission cross sections, disentangling accurately the two types of reactions. (authors)

  16. Machine Tool Technology. Automatic Screw Machine Troubleshooting & Set-Up Training Outlines [and] Basic Operator's Skills Set List.

    ERIC Educational Resources Information Center

    Anoka-Hennepin Technical Coll., Minneapolis, MN.

    This set of two training outlines and one basic skills set list are designed for a machine tool technology program developed during a project to retrain defense industry workers at risk of job loss or dislocation because of conversion of the defense industry. The first troubleshooting training outline lists the categories of problems that develop…

  17. Study of boron detection limit using the in-air PIGE set-up at LAMFI-USP

    SciTech Connect

    Moro, M. V.; Silva, T. F.; Trindade, G. F.; Added, N.; Tabacniks, M. H.

    2014-11-11

    The quantification of small amounts of boron in materials is of extreme importance in different areas of materials science. Boron is an important contaminant and also a silicon dopant in the semiconductor industry. Boron is also extensively used in nuclear power plants, either for neutron shielding or for safety control and boron is an essential nutrient for life, either vegetable or animal. The production of silicon solar cells, by refining metallurgical-grade silicon (MG-Si) requires the control and reduction of several silicon contaminants to very low concentration levels. Boron is one of the contaminants of solar-grade silicon (SG-Si) that must be controlled and quantified at sub-ppm levels. In the metallurgical purification, boron quantification is usually made by Inductive Coupled Plasma Mass Spectrometry, (ICP-MS) but the results need to be verified by an independent analytical method. In this work we present the results of the analysis of silicon samples by Particle Induced Gamma-Ray Emission (PIGE) aiming the quantification of low concentrations of boron. PIGE analysis was carried out using the in-air external beam line of the Laboratory for Materials Analysis with Ion Beams (LAMFI-USP) by the {sup 10}B(p,αγ({sup 7}Be nuclear reaction, and measuring the 429 keV γ-ray. The in-air PIGE measurements at LAMFI have a quantification limit of the order of 10{sup 16} at/cm{sup 2}.

  18. Elastic and inelastic electrons in the double-slit experiment: A variant of Feynman's which-way set-up.

    PubMed

    Frabboni, Stefano; Gazzadi, Gian Carlo; Grillo, Vincenzo; Pozzi, Giulio

    2015-07-01

    Modern nanotechnology tools allowed us to prepare slits of 90 nm width and 450 nm spacing in a screen almost completely opaque to 200 keV electrons. Then by covering both slits with a layer of amorphous material and carrying out the experiment in a conventional transmission electron microscope equipped with an energy filter we can demonstrate that the diffraction pattern, taken by selecting the elastically scattered electrons, shows the presence of interference fringes, but with a bimodal envelope which can be accounted for by taking into account the non-constant thickness of the deposited layer. However, the intensity of the inelastically scattered electrons in the diffraction plane is very broad and at the limit of detectability. Therefore the experiment was repeated using an aluminum film and a microscope also equipped with a Schottky field emission gun. It was thus possible to observe also the image due to the inelastically scattered electron, which does not show interference phenomena both in the Fraunhofer or Fresnel regimes. If we assume that inelastic scattering through the thin layer covering the slits provides the dissipative process of interaction responsible for the localization mechanism, then these experiments can be considered a variant of the Feynman which-way thought experiment. PMID:25799917

  19. Elastic and inelastic electrons in the double-slit experiment: A variant of Feynman's which-way set-up.

    PubMed

    Frabboni, Stefano; Gazzadi, Gian Carlo; Grillo, Vincenzo; Pozzi, Giulio

    2015-07-01

    Modern nanotechnology tools allowed us to prepare slits of 90 nm width and 450 nm spacing in a screen almost completely opaque to 200 keV electrons. Then by covering both slits with a layer of amorphous material and carrying out the experiment in a conventional transmission electron microscope equipped with an energy filter we can demonstrate that the diffraction pattern, taken by selecting the elastically scattered electrons, shows the presence of interference fringes, but with a bimodal envelope which can be accounted for by taking into account the non-constant thickness of the deposited layer. However, the intensity of the inelastically scattered electrons in the diffraction plane is very broad and at the limit of detectability. Therefore the experiment was repeated using an aluminum film and a microscope also equipped with a Schottky field emission gun. It was thus possible to observe also the image due to the inelastically scattered electron, which does not show interference phenomena both in the Fraunhofer or Fresnel regimes. If we assume that inelastic scattering through the thin layer covering the slits provides the dissipative process of interaction responsible for the localization mechanism, then these experiments can be considered a variant of the Feynman which-way thought experiment.

  20. Development of a multipurpose beam foil spectroscopy set-up for the low cross-section measurements

    NASA Astrophysics Data System (ADS)

    Sharma, Gaurav; Nandi, T.; Berry, H. G.; Puri, Nitin K.

    2016-08-01

    A multipurpose facility for low cross section measurements has been developed at Inter University Accelerator Centre, New Delhi, India. The facility consists of a multipurpose miniature chamber equipped with 1 m focal length normal incidence Monochromator and charge coupled device based detection system which has been aligned to realize the best resolution of the spectrometer. The chamber in this facility collects radiation 100 times more efficiently from the older system, without using any extra focusing mirror assembly. It is ensured to have the provision of mounting an X-ray detector and the spectrometer transverse to the beam direction simultaneously in the same chamber. The atomic spectroscopic studies can be performed by interaction of ions beams with both thin foil and gas targets. Provision for using photomultiplier tube instead of charge coupled device, is employed in the system depending on the condition of the source strength or other detection issues. We observed the essence of a very weak atomic phenomenon, a triply excited autoionizing forbidden transition, using the above facility to demonstrate its capability for measuring such low cross section phenomena. The present developed facility covers a large spectroscopic region from X-rays to the near infrared (0.1-10,000 Å).

  1. A novel set-up to investigate the low-frequency spectra of aqueous solutions at high hydrostatic pressure

    NASA Astrophysics Data System (ADS)

    Knake, L.; Vondracek, H.; Havenith, M.

    2016-10-01

    We present a novel setup to investigate the low frequency (THz/FIR) spectra of an aqueous solution under high hydrostatic pressure (HHP). By integration of a diamond anvil cell into a THz Fourier transform spectrometer, we are able to record the absorption of bulk water in the pressure range from 1 bar to 10 kbar. The difference in intensity can directly be compared to the difference in extinction coefficients. The spectroscopic data reveal a blue shift of the H-bond stretch vibration at 180 cm-1, which is evidence of changes in the H-bond network dynamics.

  2. Determinants of symptom profile and severity of conduct disorder in a tertiary level pediatric care set up: A pilot study

    PubMed Central

    Jayaprakash, R.; Rajamohanan, K.; Anil, P.

    2014-01-01

    Background: Conduct disorders (CDs) are one of the most common causes for referral to child and adolescent mental health centers. CD varies in its environmental factors, symptom profile, severity, co-morbidity, and functional impairment. Aims: The aim was to analyze the determinants of symptom profile and severity among childhood and adolescent onset CD. Settings and Design: Clinic based study with 60 consecutive children between 6 and 18 years of age satisfying International Classification of Disease-10 Development Control Rules guidelines for CD, attending behavioral pediatrics unit outpatient. Materials and Methods: The family psychopathology, symptom severity, and functional level were assessed using parent interview schedule, revised behavioral problem checklist and Children's Global Assessment Scale. Statistical Analysis: The correlation and predictive power of the variables were analyzed using SPSS 16.0 version. Results: There was significant male dominance (88.3%) with boy girl ratio 7.5:1. Most common comorbidity noticed was hyperkinetic disorders (45%). Childhood onset group was more predominant (70%). Prevalence of comorbidity was more among early onset group (66.7%) than the late-onset group (33.3%). The family psychopathology, symptom severity, and the functional impairment were significantly higher in the childhood onset group. Conclusion: The determinants of symptom profile and severity are early onset (childhood onset CD), nature, and quantity of family psychopathology, prevalence, and type of comorbidity and nature of symptom profile itself. The family psychopathology is positively correlated with the symptom severity and negatively correlated with the functional level of the children with CD. The symptom severity was negatively correlated with the functional level of the child with CD. PMID:25568472

  3. Cone Beam CT Image Guidance for Intracranial Stereotactic Treatments: Comparison With a Frame Guided Set-Up

    SciTech Connect

    Masi, Laura Casamassima, Franco; Polli, Caterina; Menichelli, Claudia; Bonucci, Ivano; Cavedon, Carlo

    2008-07-01

    Purpose: An analysis is performed of the setup errors measured by a kV cone beam computed tomography (CBCT) for intracranial stereotactic radiotherapy (SRT) patients immobilized by a thermoplastic mask and a bite-block and positioned using stereotactic coordinates. We evaluated the overall positioning precision and accuracy of the immobilizing and localizing systems. The potential of image-guided radiotherapy to replace stereotactic methods is discussed. Methods and Materials: Fifty-seven patients received brain SRT. After a frame-guided setup, before each fraction (131 fractions), a CBCT was acquired and the detected displacements corrected online. Translational and rotational errors were analyzed calculating overall mean and standard deviation. A separate analysis was performed for bite-block (in conjunction with mask) and for simple thermoplastic mask. Interobserver variability for CBCT three-dimensional registration was assessed. The residual error after correction and intrafractional motion were calculated. Results: The mean module of the three-dimensional displacement vector was 3.0 {+-} 1.4 mm. Setup errors for bite block and mask were smaller (2.9 {+-} 1.3 mm) than those for thermoplastic mask alone (3.2 {+-} 1.5 mm), but statistical significance was not reached (p = 0.15). Interobserver variability was negligible. The maximum margin calculated for residual errors and intra fraction motion was small but not negligible (1.57 mm). Conclusions: Considering the detected setup errors, daily image guidance is essential for the efficacy of SRT treatments when mask immobilization is used, and even when a bite-block is used in conjunction. The frame setup is still used as a starting point for the opportunity of rotational corrections. Residual margins after on-line corrections must be evaluated.

  4. A Treatment Planning Investigation Into the Dosimetric Effects of Systematic Prostate Patient Rotational Set-Up Errors

    SciTech Connect

    Cranmer-Sargison, Gavin

    2008-10-01

    The purpose of this study was to investigate the potential dosimetric effects of systematic rotational setup errors on prostate patients planned according to the RTOG P-0126 protocol, and to identify rotational tolerances about either the anterior-posterior (AP) or left-right (LR) axis, under which no correction in setup is required. Eight 3-dimensional conformal radiation therapy (3D-CRT) treatment plans were included in the study, half planned to give 7020 cGy in 39 fractions (P-0126 Arm 1) and the other half planned to give 7920 cGy in 44 fractions (P-0126 Arm 2). Systematic rotations of the pelvic anatomy were simulated in a commercial treatment planning system by rotating opposing apertures in the opposite direction to the simulated anatomy rotation. Rotations were incremented in steps of 2.5 deg. to a maximum of {+-}5.0 deg. and {+-}10.0 deg. the AP and LR axis respectively. Dose distributions were evaluated with respect to the planning objectives set out in the P-0126 protocol. For patients on Arm 2 of the study, maintaining the prescribed dose to 98% of the PTV was found to be problematic for superior-end-posterior rotations beyond 5.0 deg. The results also show that maintaining a rectal dose less than 7500 cGy to 15% of the volume can become problematic for cases of small rectal volume and large superior-end-anterior rotations. We found that setting rotational tolerances will depend on which Arm of the protocol the patient is, and how well the initial plan meets the protocol objectives. In general, we conclude that for rotations about the AP axis, no tolerance level is required; however, cases presenting extreme rotations should be investigated as routine practice. For rotations about the LR axis, we conclude that a tolerance level for patients on Arm 2 of the protocol should be set at {+-}5.0 deg. This tolerance represents the systematic setup error which would require correction if a variation to the initial plan was deemed unacceptable.

  5. Analysis of Fine and Coarse mode Aerosol Distributions from AERONET's mini-DRAGON Set-up at Singapore 2012

    NASA Astrophysics Data System (ADS)

    Salinas Cortijo, S. V.; Chew, B. N.; Muller, A.; Liew, S.

    2013-12-01

    Aerosol optical depth combined with the Angstrom exponent and its derivative, are often used as a qualitative indicator of aerosol type and particle size regime. In Singapore, the sources of aerosols are mostly from fossil fuel burning (energy stations, incinerators, urban transport etc.) and from industrial and urban areas. However, depending on the time of the year (July-October), there can be a strong bio-mass component originated from uncontrolled forest/plantation fires from the neighboring land masses of Sumatra and Borneo. Unlike urban/fossil fuel aerosols, smoke or bio-mass related aerosol particles are typically characterized by showing a large optical depth and small, sub-micron particle size distributions. Trans-boundary smoke episodes has become an annual phenomenon in this region. Severe episodes were recorded in 1997 and 2006 and other minor episodes happened during 2002, 2004, 2010 and more recently on 2013. On August-September 2012, as part of CRISP participation on the August-September ground campaign of the Southeast Asia Composition, Cloud Climate Coupling Regional Study (SEAC4RS), a Distributed Regional Aerosol Gridded Observation Networks (DRAGON) set of six CIMEL CE-318A automatic Sun-tracking photometers have been deployed at sites located at North (Yishun ITE), East (Temasek Poly), West (NUS and Pandan Reservoir), Central (NEA) and South (St. John's island) of Singapore. In order to fully discriminate bio-mass burning events over other local sources, we perform a spectral discrimination of fine/coarse mode particle regime to all DRAGON sites; subsequently, the fine mode parameters such as optical depth, optical ratio and fine mode Angstrom exponent are used to identify possible bio-mass related events within the data set. Spatio-temporal relationship between sites are also investigated.

  6. Enzymatic Cleavage of Glycosidic Bonds: Strategies on How to Set Up and Control a QM/MM Metadynamics Simulation.

    PubMed

    Raich, L; Nin-Hill, A; Ardèvol, A; Rovira, C

    2016-01-01

    Carbohydrates play crucial roles in many biological processes, from cell-cell adhesion to chemical signaling. Their complexity and diversity, related to α/β anomeric configuration, ring substituents, and conformational variations, require a diverse set of enzymes for their processing. Among them, glycoside hydrolases (GHs) are responsible for the hydrolysis of one of the strongest bonds in nature: the glycosidic bond. These highly specialized biological catalysts select particular conformations their carbohydrate substrates to enhance catalysis. The evolution of this conformation during the reaction of glycosidic bond cleavage, known as the conformational catalytic itinerary, is of fundamental interest in glycobiology, with impact on inhibitor and drug design. Here we review some of the aspects and the main strategies one needs to take into account when simulating a reaction in a GH enzyme using QM/MM metadynamics. Several specific aspects are highlighted, from the importance of the distortion of the substrate at the Michaelis complex to the variable control during the metadynamics simulation or the analysis of the reaction mechanism and conformational itinerary. The increasing speed of computer power and methodological advances have added a vital tool to the study of GH mechanisms, as shown here and recent reviews. It is hoped that this chapter will serve as a first guide for those attempting to perform a metadynamics simulation of these relevant and fascinating enzymes. PMID:27498638

  7. [Breast cancer: end of treatment issues and set up of nursing follow up in the Italian Switzerland Breast Unit].

    PubMed

    Pedrazzani, Carla; Anelli, Simona; Manganiello, Lucia

    2013-01-01

    It's widely recognized the important role that nurses can have in identifying and managing problems of various kinds resulting from the illness and treatment in survivor cancer patients, so that clinical nursing follow-up programs for cancer patients are now widely diffused internationally. The aim of the following study is the detection of the main physical, emotional, social-familial problems of women with breast cancer followed by the Italian Switzerland Breast Unit, after the end of treatment in order to better target the activation of a nursing follow-up program. This is a descriptive study. Data were collected through a questionnaire mailed to all patients who underwent surgery in the Breast Unit from 2005 to 2009 for a total of 527 patients. The statistical analysis of data was carried out on a total of 202 patients. Fatigue is the physical problem most highlighted by the sample of women (52%), followed by bone pain and / or muscle pain (45.5%) and hot flushes (44.1%). On an emotional level, fear and worry are reported by 40.1% of women, followed by sadness reported by 31.3% of women. Regarding the socio-familial aspect, one of 5 women shows working difficulties (21.2%). Statistically significant correlations are highlighted between some problems and some contextual variables (age, type of treatment, time from the end of treatment). The study has allowed to characterize this population in the specific context and to structure a nursing follow-up program which is active since January 2012.

  8. Utilizing Gaussian Markov random field properties of Bayesian animal models.

    PubMed

    Steinsland, Ingelin; Jensen, Henrik

    2010-09-01

    In this article, we demonstrate how Gaussian Markov random field properties give large computational benefits and new opportunities for the Bayesian animal model. We make inference by computing the posteriors for important quantitative genetic variables. For the single-trait animal model, a nonsampling-based approximation is presented. For the multitrait model, we set up a robust and fast Markov chain Monte Carlo algorithm. The proposed methodology was used to analyze quantitative genetic properties of morphological traits of a wild house sparrow population. Results for single- and multitrait models were compared.

  9. Visual setup of logical models of signaling and regulatory networks with ProMoT

    PubMed Central

    Saez-Rodriguez, Julio; Mirschel, Sebastian; Hemenway, Rebecca; Klamt, Steffen; Gilles, Ernst Dieter; Ginkel, Martin

    2006-01-01

    Background The analysis of biochemical networks using a logical (Boolean) description is an important approach in Systems Biology. Recently, new methods have been proposed to analyze large signaling and regulatory networks using this formalism. Even though there is a large number of tools to set up models describing biological networks using a biochemical (kinetic) formalism, however, they do not support logical models. Results Herein we present a flexible framework for setting up large logical models in a visual manner with the software tool ProMoT. An easily extendible library, ProMoT's inherent modularity and object-oriented concept as well as adaptive visualization techniques provide a versatile environment. Both the graphical and the textual description of the logical model can be exported to different formats. Conclusion New features of ProMoT facilitate an efficient set-up of large Boolean models of biochemical interaction networks. The modeling environment is flexible; it can easily be adapted to specific requirements, and new extensions can be introduced. ProMoT is freely available from . PMID:17109765

  10. LDV measurements in an annular combustor model. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Barron, Dean A.

    1986-01-01

    The design and setup of a Laser Doppler Velocimeter (LDV) system used to take velocity measurements in an annular combustor model are covered. The annular combustor model is of contemporary design using 60 degree flat vane swirlers, producing a strong recirculation zone. Detailed measurements are taken of the swirler inlet air flow and of the downstream enclosed swirling flow. The laser system used is a two color, two component system set up in forward scatter. Detailed are some of the special considerations needed for LDV use in the confined turbulent flow of the combustor model. The LDV measurements in a single swirler rig indicated that the flow changes radically in the first duct height. After this, a flow profile is set up and remains constant in shape. The magnitude of the velocities gradually decays due to viscous damping.

  11. The Antares computing model

    NASA Astrophysics Data System (ADS)

    Kopper, Claudio; Antares Collaboration

    2013-10-01

    Completed in 2008, Antares is now the largest water Cherenkov neutrino telescope in the Northern Hemisphere. Its main goal is to detect neutrinos from galactic and extra-galactic sources. Due to the high background rate of atmospheric muons and the high level of bioluminescence, several on-line and off-line filtering algorithms have to be applied to the raw data taken by the instrument. To be able to handle this data stream, a dedicated computing infrastructure has been set up. The paper covers the main aspects of the current official Antares computing model. This includes an overview of on-line and off-line data handling and storage. In addition, the current usage of the “IceTray” software framework for Antares data processing is highlighted. Finally, an overview of the data storage formats used for high-level analysis is given.

  12. Modeling

    SciTech Connect

    Loth, E.; Tryggvason, G.; Tsuji, Y.; Elghobashi, S. E.; Crowe, Clayton T.; Berlemont, A.; Reeks, M.; Simonin, O.; Frank, Th; Onishi, Yasuo; Van Wachem, B.

    2005-09-01

    Slurry flows occur in many circumstances, including chemical manufacturing processes, pipeline transfer of coal, sand, and minerals; mud flows; and disposal of dredged materials. In this section we discuss slurry flow applications related to radioactive waste management. The Hanford tank waste solids and interstitial liquids will be mixed to form a slurry so it can be pumped out for retrieval and treatment. The waste is very complex chemically and physically. The ARIEL code is used to model the chemical interactions and fluid dynamics of the waste.

  13. Earth System Chemistry integrated Modelling (ESCiMo) with the Modular Earth Submodel System (MESSy) version 2.51

    NASA Astrophysics Data System (ADS)

    Jöckel, Patrick; Tost, Holger; Pozzer, Andrea; Kunze, Markus; Kirner, Oliver; Brenninkmeijer, Carl A. M.; Brinkop, Sabine; Cai, Duy S.; Dyroff, Christoph; Eckstein, Johannes; Frank, Franziska; Garny, Hella; Gottschaldt, Klaus-Dirk; Graf, Phoebe; Grewe, Volker; Kerkweg, Astrid; Kern, Bastian; Matthes, Sigrun; Mertens, Mariano; Meul, Stefanie; Neumaier, Marco; Nützel, Matthias; Oberländer-Hayn, Sophie; Ruhnke, Roland; Runde, Theresa; Sander, Rolf; Scharffe, Dieter; Zahn, Andreas

    2016-03-01

    Three types of reference simulations, as recommended by the Chemistry-Climate Model Initiative (CCMI), have been performed with version 2.51 of the European Centre for Medium-Range Weather Forecasts - Hamburg (ECHAM)/Modular Earth Submodel System (MESSy) Atmospheric Chemistry (EMAC) model: hindcast simulations (1950-2011), hindcast simulations with specified dynamics (1979-2013), i.e. nudged towards ERA-Interim reanalysis data, and combined hindcast and projection simulations (1950-2100). The manuscript summarizes the updates of the model system and details the different model set-ups used, including the on-line calculated diagnostics. Simulations have been performed with two different nudging set-ups, with and without interactive tropospheric aerosol, and with and without a coupled ocean model. Two different vertical resolutions have been applied. The on-line calculated sources and sinks of reactive species are quantified and a first evaluation of the simulation results from a global perspective is provided as a quality check of the data. The focus is on the intercomparison of the different model set-ups. The simulation data will become publicly available via CCMI and the Climate and Environmental Retrieval and Archive (CERA) database of the German Climate Computing Centre (DKRZ). This manuscript is intended to serve as an extensive reference for further analyses of the Earth System Chemistry integrated Modelling (ESCiMo) simulations.

  14. User’s guide and reference to Ash3d: a three-dimensional model for Eulerian atmospheric tephra transport and deposition

    USGS Publications Warehouse

    Mastin, Larry G.; Randall, Michael J.; Schwaiger, Hans F.; Denlinger, Roger P.

    2013-01-01

    Ash3d is a three-dimensional Eulerian atmospheric model for tephra transport, dispersal, and deposition, written by the authors to study and forecast hazards of volcanic ash clouds and tephra fall. In this report, we explain how to set up simulations using both a web interface and an ASCII input file, and how to view and interpret model output. We also summarize the architecture of the model and some of its properties.

  15. A New Model for Food Chain

    NASA Astrophysics Data System (ADS)

    Liu, Chung-Chu; Liu, Xia-Shi

    2002-01-01

    An experiment for a new model of food chain was studied. In this special circulating system we succeeded in integrating animal, fish and plant production into a new model of food chain. The advantages of the new model are as follows: A. The new model of food chain was under special water circulating system. Hence water consumption was minimized and it would be possible to be use the model in the area where water shortage. B. Output of this model was ten times more than that of output in the conventional production system, for example the products obtained from new model in an area of 66m3 exceeded same amount of products obtained from conventional production system in an area of 660m3. It may be possible to raise the output up to 20-fold if better management is made. In that case, such high output and high water use efficiency may be a hopeful base for the study to set up a new biosphere on Moon and Mars. C. Growth of the plant in this model will mainly depend on its own circulation without add fertilizer and pesticide except for supplementary certain food to feed the animal and fish product, Hence, the products from this model will be no pollution food. In our primary experiment shows that rice, celery, water convolvulus, water spinach and tomato growing well in this model. D. By use of water circulating system there will be no pollution to ecosystem. E. Based on this new model of food chain, it is possible to start the experiment on setting up the artificial biosphere No.. Key words: Food chain, Water circulating system, Artificial biosphere

  16. The research for means of image appraisal and simulation model

    NASA Astrophysics Data System (ADS)

    Liu, Kailong; Lv, Xvliang; Zhu, Jinsong; Sun, Xiangjun

    2004-03-01

    During the course of image effect evaluation, random and fuzzy factors are both included. Traditional effect evaluation theory adopts classical probability statistical method, which only shows the random factors of remote sensing exploration system, and does not show the influential factors of psycho-physics and psycho-physiology, which are fuzzy factors, hard to be described and quantized exactly. The image effect evaluation method and computer simulation model are set up based on the interaction of mathematical model and probability statistics, and on the Hamming distance. The technology and thinking method can be applied to solve the problem of image effect evaluation in other similar systems.

  17. Marine-current power generation model for smart grids

    NASA Astrophysics Data System (ADS)

    Vlachogiannis, John G.

    2014-03-01

    This short communication introduces the first marine-current power generation model to be integrated into power flow studies of smart grids. The stochastic aspect of marine-current velocity affecting the real power output of marine-current generators is provided by a closed formula. Also, a new closed formula for power coefficient of marine-current generators versus marine-current velocities is set up. The introduced marine-current power generation model is validated on real measurements obtained in the sub-sea areas of Alderney Race (Channel Islands) in UK and Gun-barrel passage in Fiji.

  18. Application of the Chameleon Model to EM Field Momentum

    NASA Astrophysics Data System (ADS)

    Robertson, Glen A.

    2008-01-01

    The Chameleon scalar field model proposed by Khoury and Weltman presents an alternative mechanism for circumventing the constraints from local tests of gravity by mediating a fifth force for cosmological expansion, which could result in experimental signatures detectable through modest improvements of current laboratory set-ups in the vicinity of oscillating matter. In this paper, the oscillation of a dielectric by a crossed EM field is investigated in light of the Chameleon model. An EM excited Chameleon field-force equation is developed and compared to several EM experiments using the Barium Titanate based dielectric material.

  19. Landsat analysis of tropical forest succession employing a terrain model

    NASA Technical Reports Server (NTRS)

    Barringer, T. H.; Robinson, V. B.; Coiner, J. C.; Bruce, R. C.

    1980-01-01

    Landsat multispectral scanner (MSS) data have yielded a dual classification of rain forest and shadow in an analysis of a semi-deciduous forest on Mindonoro Island, Philippines. Both a spatial terrain model, using a fifth side polynomial trend surface analysis for quantitatively estimating the general spatial variation in the data set, and a spectral terrain model, based on the MSS data, have been set up. A discriminant analysis, using both sets of data, has suggested that shadowing effects may be due primarily to local variations in the spectral regions and can therefore be compensated for through the decomposition of the spatial variation in both elevation and MSS data.

  20. Development and applications of a multi-level strain energy method for detecting finite element modeling errors

    NASA Technical Reports Server (NTRS)

    Hashemi-Kia, Mostafa; Kilroy, Kevin L.; Parker, G.

    1990-01-01

    A computational procedure is described which can be used efficiently in identifying modeling errors which may arise from development of a structural finite element model. The procedure, which is referred to as the multi-level strain energy check, is set up in the form of a set of NASTRAN DMAP alters which provide sufficient information about the modeling errors at G-Set, N-Set, and F-Set levels. This technique was applied to two NASTRAN models, namely, the AH-64A and AH-1G models. Two modeling errors were identified for the AH-1G, which were then corrected.

  1. RIMBAY - a multi-approximation 3D ice-dynamics model for comprehensive applications: model description and examples

    NASA Astrophysics Data System (ADS)

    Thoma, M.; Grosfeld, K.; Barbi, D.; Determann, J.; Goeller, S.; Mayer, C.; Pattyn, F.

    2014-01-01

    Glaciers and ice caps exhibit currently the largest cryospheric contributions to sea level rise. Modelling the dynamics and mass balance of the major ice sheets is therefore an important issue to investigate the current state and the future response of the cryosphere in response to changing environmental conditions, namely global warming. This requires a powerful, easy-to-use, versatile multi-approximation ice dynamics model. Based on the well-known and established ice sheet model of Pattyn (2003) we develop the modular multi-approximation thermomechanic ice model RIMBAY, in which we improve the original version in several aspects like a shallow ice-shallow shelf coupler and a full 3D-grounding-line migration scheme based on Schoof's (2007) heuristic analytical approach. We summarise the full Stokes equations and several approximations implemented within this model and we describe the different numerical discretisations. The results are cross-validated against previous publications dealing with ice modelling, and some additional artificial set-ups demonstrate the robustness of the different solvers and their internal coupling. RIMBAY is designed for an easy adaption to new scientific issues. Hence, we demonstrate in very different set-ups the applicability and functionality of RIMBAY in Earth system science in general and ice modelling in particular.

  2. Research Results Ultra-fast Energy Transfer from Monomer to Dimer within a Trimeric Molecule New Progress in Heterogeneous Catalysis Research Key Progress in Research on Terrestrial Carbon Cycle in China A New Progress in Research on the Mechanism of Bio-Invasion New Findings in Anti-viral infection and Control of Inflammation Major Headway in Avian Origin Research New Progress in Gold-Nanoparticle-Based Biochips Topological Insulator Research Made Important Progress Major Progress in Biodiversity Achieved New Developments of Direct Methods in Protein Crystallography Major Progress in China-UK Collaboration on the Causal Relationship between Volcanic Activity and Biological Distinction News in Brief: NSFC set up "Research Fund for Young Foreign Scholars" How Often Does Human DNA Mutate? Research Progress on Colossal Anisotropic Magneto Resistive Effect

    NASA Astrophysics Data System (ADS)

    2009-01-01

    Ultra-fast Energy Transfer from Monomer to Dimer within a Trimeric Molecule New Progress in Heterogeneous Catalysis Research Key Progress in Research on Terrestrial Carbon Cycle in China A New Progress in Research on the Mechanism of Bio-Invasion New Findings in Anti-viral infection and Control of Inflammation Major Headway in Avian Origin Research New Progress in Gold-Nanoparticle-Based Biochips Topological Insulator Research Made Important Progress Major Progress in Biodiversity Achieved New Developments of Direct Methods in Protein Crystallography Major Progress in China-UK Collaboration on the Causal Relationship between Volcanic Activity and Biological Distinction News in Brief: NSFC set up "Research Fund for Young Foreign Scholars" How Often Does Human DNA Mutate? Research Progress on Colossal Anisotropic Magneto Resistive Effect

  3. The Inter-Sectoral Impact Model Intercomparison Project (ISI–MIP): Project framework

    PubMed Central

    Warszawski, Lila; Frieler, Katja; Huber, Veronika; Piontek, Franziska; Serdeczny, Olivia; Schewe, Jacob

    2014-01-01

    The Inter-Sectoral Impact Model Intercomparison Project offers a framework to compare climate impact projections in different sectors and at different scales. Consistent climate and socio-economic input data provide the basis for a cross-sectoral integration of impact projections. The project is designed to enable quantitative synthesis of climate change impacts at different levels of global warming. This report briefly outlines the objectives and framework of the first, fast-tracked phase of Inter-Sectoral Impact Model Intercomparison Project, based on global impact models, and provides an overview of the participating models, input data, and scenario set-up. PMID:24344316

  4. Ameliorating GM (1, 1) Model Based on the Structure of the Area under Trapezium

    NASA Astrophysics Data System (ADS)

    Li, Cuifeng

    According to the research on the structure of background value in the GM(1,1) model, the structure method of background value, a exact formula about the background value of χ (1)(t) in the region [k,k + 1],which is used when establishing GM(1,1), is established by integrating χ (1)(t) from k to k + 1 .The modeling precision and prediction precision of the ameliorating background value can be advanced. Moreover, the application area of GM(1,1) model can be enlarged. At last, the model of Chinese per-power is set up. Simulation examples show the effectiveness of the proposed approach.

  5. The Inter-Sectoral Impact Model Intercomparison Project (ISI-MIP): project framework.

    PubMed

    Warszawski, Lila; Frieler, Katja; Huber, Veronika; Piontek, Franziska; Serdeczny, Olivia; Schewe, Jacob

    2014-03-01

    The Inter-Sectoral Impact Model Intercomparison Project offers a framework to compare climate impact projections in different sectors and at different scales. Consistent climate and socio-economic input data provide the basis for a cross-sectoral integration of impact projections. The project is designed to enable quantitative synthesis of climate change impacts at different levels of global warming. This report briefly outlines the objectives and framework of the first, fast-tracked phase of Inter-Sectoral Impact Model Intercomparison Project, based on global impact models, and provides an overview of the participating models, input data, and scenario set-up.

  6. Shuttle cryogenics supply system optimization study. Volume 5, B-3, part 2: Appendix to programmers manual for math model

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A computer programmer's manual for a digital computer which will permit rapid and accurate parametric analysis of current and advanced attitude control propulsion systems is presented. The concept is for a cold helium pressurized, subcritical cryogen fluid supplied, bipropellant gas-fed attitude control propulsion system. The cryogen fluids are stored as liquids under low pressure and temperature conditions. The mathematical model provides a generalized form for the procedural technique employed in setting up the analysis program.

  7. On the use of inexact, pruned hardware in atmospheric modelling

    PubMed Central

    Düben, Peter D.; Joven, Jaume; Lingamneni, Avinash; McNamara, Hugh; De Micheli, Giovanni; Palem, Krishna V.; Palmer, T. N.

    2014-01-01

    Inexact hardware design, which advocates trading the accuracy of computations in exchange for significant savings in area, power and/or performance of computing hardware, has received increasing prominence in several error-tolerant application domains, particularly those involving perceptual or statistical end-users. In this paper, we evaluate inexact hardware for its applicability in weather and climate modelling. We expand previous studies on inexact techniques, in particular probabilistic pruning, to floating point arithmetic units and derive several simulated set-ups of pruned hardware with reasonable levels of error for applications in atmospheric modelling. The set-up is tested on the Lorenz ‘96 model, a toy model for atmospheric dynamics, using software emulation for the proposed hardware. The results show that large parts of the computation tolerate the use of pruned hardware blocks without major changes in the quality of short- and long-time diagnostics, such as forecast errors and probability density functions. This could open the door to significant savings in computational cost and to higher resolution simulations with weather and climate models. PMID:24842031

  8. On the use of inexact, pruned hardware in atmospheric modelling.

    PubMed

    Düben, Peter D; Joven, Jaume; Lingamneni, Avinash; McNamara, Hugh; De Micheli, Giovanni; Palem, Krishna V; Palmer, T N

    2014-06-28

    Inexact hardware design, which advocates trading the accuracy of computations in exchange for significant savings in area, power and/or performance of computing hardware, has received increasing prominence in several error-tolerant application domains, particularly those involving perceptual or statistical end-users. In this paper, we evaluate inexact hardware for its applicability in weather and climate modelling. We expand previous studies on inexact techniques, in particular probabilistic pruning, to floating point arithmetic units and derive several simulated set-ups of pruned hardware with reasonable levels of error for applications in atmospheric modelling. The set-up is tested on the Lorenz '96 model, a toy model for atmospheric dynamics, using software emulation for the proposed hardware. The results show that large parts of the computation tolerate the use of pruned hardware blocks without major changes in the quality of short- and long-time diagnostics, such as forecast errors and probability density functions. This could open the door to significant savings in computational cost and to higher resolution simulations with weather and climate models.

  9. Model of adaptive temporal development of structured finite systems

    NASA Astrophysics Data System (ADS)

    Patera, Jiri; Shaw, Gordon L.; Slansky, Richard; Leng, Xiaodan

    1989-07-01

    The weight systems of level-zero representations of affine Kac-Moody algebras provide an appropriate kinematical framework for studying structured finite systems with adaptive temporal development. Much of the structure is determined by Lie algebra theory, so it is possible to restrict greatly the connection space and analytic results are possible. The time development of these systems often evolves to cyclic temporal-spatial patterns, depending on the definition of the dynamics. The purpose of this paper is to set up the mathematical formalism for this ``memory in Lie algebras'' class of models. An illustration is used to show the kinds of complex behavior that occur in simple cases.

  10. Virtual building environments (VBE) - Applying information modeling to buildings

    SciTech Connect

    Bazjanac, Vladimir

    2004-06-21

    A Virtual Building Environment (VBE) is a ''place'' where building industry project staffs can get help in creating Building Information Models (BIM) and in the use of virtual buildings. It consists of a group of industry software that is operated by industry experts who are also experts in the use of that software. The purpose of a VBE is to facilitate expert use of appropriate software applications in conjunction with each other to efficiently support multidisciplinary work. This paper defines BIM and virtual buildings, and describes VBE objectives, set-up and characteristics of operation. It informs about the VBE Initiative and the benefits from a couple of early VBE projects.

  11. Wall stress and deformation analysis in a numerical model of pulse wave propagation.

    PubMed

    He, Fan; Hua, Lu; Gao, Lijian

    2015-01-01

    To simulate pulse wave propagation, we set up a wave propagation model using blood-wall interaction in previous work. In this paper, our purpose is to investigate wall stress and deformation of the wave propagation model. The finite element method is employed for solving the governing equations of blood and wall. Our results suggest that there are two peaks in the circumferential stress and strain distributions of the normal model. The stress and strain values change with the varieties of different factors, such as wall thickness and vessel diameter. The results indicate that different parameters of fluid and tube wall have remarked impact on wall stress and deformation. PMID:26406044

  12. Macroscopic Conduction Models by Volume Averaging for Two-Phase Systems

    NASA Astrophysics Data System (ADS)

    Goyeau, Benoît

    The aim here is to describe macroscopic models of conductive heat transfer within systems comprising two solid phases, using the method of volume averaging. The presentation of this technique largely stems from work by Carbonell, Quintard, and Whitaker [1-3]. The macroscopic conservation equations are set up under the assumption of local thermal equilibrium, leading to a model governed by a single equation. The effective thermal conductivity of the equivalent medium is obtained by solving the associated closure problems. The case where thermal equilibrium does not pertain, leading to a model with two energy conservation equations, is discussed briefly.

  13. Wall stress and deformation analysis in a numerical model of pulse wave propagation.

    PubMed

    He, Fan; Hua, Lu; Gao, Lijian

    2015-01-01

    To simulate pulse wave propagation, we set up a wave propagation model using blood-wall interaction in previous work. In this paper, our purpose is to investigate wall stress and deformation of the wave propagation model. The finite element method is employed for solving the governing equations of blood and wall. Our results suggest that there are two peaks in the circumferential stress and strain distributions of the normal model. The stress and strain values change with the varieties of different factors, such as wall thickness and vessel diameter. The results indicate that different parameters of fluid and tube wall have remarked impact on wall stress and deformation.

  14. STEPS: Modeling and Simulating Complex Reaction-Diffusion Systems with Python.

    PubMed

    Wils, Stefan; De Schutter, Erik

    2009-01-01

    We describe how the use of the Python language improved the user interface of the program STEPS. STEPS is a simulation platform for modeling and stochastic simulation of coupled reaction-diffusion systems with complex 3-dimensional boundary conditions. Setting up such models is a complicated process that consists of many phases. Initial versions of STEPS relied on a static input format that did not cleanly separate these phases, limiting modelers in how they could control the simulation and becoming increasingly complex as new features and new simulation algorithms were added. We solved all of these problems by tightly integrating STEPS with Python, using SWIG to expose our existing simulation code. PMID:19623245

  15. Turbulence by Design: How to Initialize a Turbulence Model in the Case of the Rayleigh-Taylor Instability

    SciTech Connect

    Rollin, Bertrand; Andrews, Malcolm J.

    2012-07-17

    Importance of initial conditions for turbulence 'design' and prediction are that initial conditions could affect 'late-time' turbulent transport and mixing effectiveness. Hence, a challenge for prediction, but also an opportunity for turbulence 'design'. The objective is to provide a rational basis for setting up initial conditions in turbulence models. Conclusions are: (1) We constructed a modal model for multimode RT; (2) We use a two-fluid formulation for generating profiles of turbulence model variables in the self-similar regime; and (3) We defined an approach to remove any guess from initializing a turbulence model for Rayleigh-Taylor turbulent mixing.

  16. Hybrid modeling of tumor-induced angiogenesis

    NASA Astrophysics Data System (ADS)

    Bonilla, L. L.; Capasso, V.; Alvaro, M.; Carretero, M.

    2014-12-01

    When modeling of tumor-driven angiogenesis, a major source of analytical and computational complexity is the strong coupling between the kinetic parameters of the relevant stochastic branching-and-growth of the capillary network, and the family of interacting underlying fields. To reduce this complexity, we take advantage of the system intrinsic multiscale structure: we describe the stochastic dynamics of the cells at the vessel tip at their natural mesoscale, whereas we describe the deterministic dynamics of the underlying fields at a larger macroscale. Here, we set up a conceptual stochastic model including branching, elongation, and anastomosis of vessels and derive a mean field approximation for their densities. This leads to a deterministic integropartial differential system that describes the formation of the stochastic vessel network. We discuss the proper capillary injecting boundary conditions and include the results of relevant numerical simulations.

  17. Inhalational model of cocaine exposure in mice: neuroteratological effects.

    PubMed

    He, Fang; Lidow, Irina A; Lidow, Michael S

    2006-01-01

    We developed a novel inhalation-based mouse model of prenatal cocaine exposure. This model approximates cocaine abuse via smoking, the preferred route of cocaine administration by heavy drug users. The model is also characterized by (i) absence of procedural stress from drug administration, (ii) long-term drug exposure starting weeks before pregnancy and continuing throughout the entire gestation, and (iii) self-administration of cocaine in multi-hour daily sessions reminiscent of drug binges, which allows animals to set up the levels of their own drug consumption. The offspring of female mice inhaling cocaine in our model displayed no gross alterations in their cortical cytoarchitecture. These offspring, however, showed significant impairments in sustained attention and spatial working memory. We hope that the introduction of the present model will lead to a significant increase in our understanding of outcomes of prenatal cocaine exposure. PMID:16414242

  18. Cosmological perturbations in SFT inspired non-local scalar field models

    NASA Astrophysics Data System (ADS)

    Koshelev, Alexey S.; Vernov, Sergey Yu.

    2012-10-01

    We study cosmological perturbations in models with a single non-local scalar field originating from the string field theory description of the rolling tachyon dynamics. We construct the equation for the energy density perturbations of the non-local scalar field and explicitly prove that for the free field it is identical to a system of local cosmological perturbation equations in a particular model with multiple (maybe infinitely many) local free scalar fields. We also show that vector and tensor perturbations are absent in this set-up.

  19. Multi-physics modelling approach for oscillatory microengines: application for a microStirling generator design

    NASA Astrophysics Data System (ADS)

    Formosa, F.; Fréchette, L. G.

    2015-12-01

    An electrical circuit equivalent (ECE) approach has been set up allowing elementary oscillatory microengine components to be modelled. They cover gas channel/chamber thermodynamics, viscosity and thermal effects, mechanical structure and electromechanical transducers. The proposed tool has been validated on a centimeter scale Free Piston membrane Stirling engine [1]. We propose here new developments taking into account scaling effects to establish models suitable for any microengines. They are based on simplifications derived from the comparison of the hydraulic radius with respect to the viscous and thermal penetration depths respectively).

  20. P80 SRM low torque flex-seal development - thermal and chemical modeling of molding process

    NASA Astrophysics Data System (ADS)

    Descamps, C.; Gautronneau, E.; Rousseau, G.; Daurat, M.

    2009-09-01

    The development of the flex-seal component of the P80 nozzle gave the opportunity to set up new design and manufacturing process methods. Due to the short development lead time required by VEGA program, the usual manufacturing iterative tests work flow, which is usually time consuming, had to be enhanced in order to use a more predictive approach. A newly refined rubber vulcanization description was built up and identified on laboratory samples. This chemical model was implemented in a thermal analysis code. The complete model successfully supports the manufacturing processes. These activities were conducted with the support of ESA/CNES Research & Technologies and DGA (General Delegation for Armament).

  1. MEAD (part I)--a mathematical model of the long-term dispersion of radioactivity in shelf sea environments.

    PubMed

    Goshawk, J A; Clarke, S; Smith, C N; McDonald, P

    2003-01-01

    A mathematical model (MEAD) that simulates the transport of radioactivity in shelf-sea environments is presented. In the model it is assumed that the radioactivity can be present in three phases and transport both within and between the phases is captured. The set-up of the model for the Irish Sea is described and results from a simple discharge scenario are presented for (137)Cs and (239)Pu. From these results it appears that MEAD provides a good representation of the transport of radionuclides in the Irish Sea.

  2. Picturing and modelling catchments by representative hillslopes

    NASA Astrophysics Data System (ADS)

    Loritz, Ralf; Hassler, Sibylle; Jackisch, Conrad; Zehe, Erwin

    2016-04-01

    Hydrological modelling studies often start with a qualitative sketch of the hydrological processes of a catchment. These so-called perceptual models are often pictured as hillslopes and are generalizations displaying only the dominant and relevant processes of a catchment or hillslope. The problem with these models is that they are prone to become too much predetermined by the designer's background and experience. Moreover it is difficult to know if that picture is correct and contains enough complexity to represent the system under study. Nevertheless, because of their qualitative form, perceptual models are easy to understand and can be an excellent tool for multidisciplinary exchange between researchers with different backgrounds, helping to identify the dominant structures and processes in a catchment. In our study we explore whether a perceptual model built upon an intensive field campaign may serve as a blueprint for setting up representative hillslopes in a hydrological model to reproduce the functioning of two distinctly different catchments. We use a physically-based 2D hillslope model which has proven capable to be driven by measured soil-hydrological parameters. A key asset of our approach is that the model structure itself remains a picture of the perceptual model, which is benchmarked against a) geo-physical images of the subsurface and b) observed dynamics of discharge, distributed state variables and fluxes (soil moisture, matric potential and sap flow). Within this approach we are able to set up two behavioral model structures which allow the simulation of the most important hydrological fluxes and state variables in good accordance with available observations within the 19.4 km2 large Colpach catchment and the 4.5 km2 large Wollefsbach catchment in Luxembourg without the necessity of calibration. This corroborates, contrary to the widespread opinion, that a) lower mesoscale catchments may be modelled by representative hillslopes and b) physically

  3. On The Heat and Salt Exchange Between The Deep Basins of The Baltic Sea

    NASA Astrophysics Data System (ADS)

    Lehmann, A.; Hinrichsen, H.-H.

    Fluxes of volume, heat and salt have been calculated from numerical model simula- tions for different sections in areas which are important for the deep water exchange in the Baltic Sea. The calculated deep water flow in the Arkona basin is in accordance with independent estimations obtained from profile data. It is found that the strength of the upper layer low saline flow in the Arkona Basin which is on average directed to the west, opposite to the mean wind direction, is compensated by a highly saline flow in deeper layers. Increasing upper layer flow will result in an increased lower layer flow in opposite direction indicating a baroclinic control. The annual mean flow is negatively correlated with the annual mean runoff to the Baltic Sea. In accordance to the mean circulation, the flow through the Bornholm Gat is on average directed to the east, and south of Bornholm the flow is directed to the west indicating an import of heat and salt to the Bornholm Basin through the Bornholm Gat and an export south of Bornholm. Flux characteristics change further downstream in the Stolpe Trench. The volume flow in the upper layer shows a strong seasonal signal. During autumn to spring the flow is mainly directed to the east, in summer the flow direction is reversed. Flow in westerly directions is related to increased lower layer flow in easterly direc- tions. On average the net flow through the Stolpe channel is directed to the east which is in accordance with the mean circulation. The calculated fluxes show high intra- and interannual variability with no obvious trend during the simulation period.

  4. Pan-European modelling of riverine nutrient concentrations - spatial patterns, source detection, trend analyses, scenario modelling

    NASA Astrophysics Data System (ADS)

    Bartosova, Alena; Arheimer, Berit; Capell, Rene; Donnelly, Chantal; Strömqvist, Johan

    2016-04-01

    Nutrient transport models are important tools for large scale assessments of macro-nutrient fluxes (nitrogen, phosphorus) and thus can serve as support tool for environmental assessment and management. Results from model applications over large areas, i.e. from major river basin to continental scales can fill a gap where monitoring data is not available. Here, we present results from the pan-European rainfall-runoff and nutrient transfer model E-HYPE, which is based on open data sources. We investigate the ability of the E-HYPE model to replicate the spatial and temporal variations found in observed time-series of riverine N and P concentrations, and illustrate the model usefulness for nutrient source detection, trend analyses, and scenario modelling. The results show spatial patterns in N concentration in rivers across Europe which can be used to further our understanding of nutrient issues across the European continent. E-HYPE results show hot spots with highest concentrations of total nitrogen in Western Europe along the North Sea coast. Source apportionment was performed to rank sources of nutrient inflow from land to sea along the European coast. An integrated dynamic model as E-HYPE also allows us to investigate impacts of climate change and measure programs, which was illustrated in a couple of scenarios for the Baltic Sea. Comparing model results with observations shows large uncertainty in many of the data sets and the assumptions used in the model set-up, e.g. point source release estimates. However, evaluation of model performance at a number of measurement sites in Europe shows that mean N concentration levels are generally well simulated. P levels are less well predicted which is expected as the variability of P concentrations in both time and space is higher. Comparing model performance with model set-ups using local data for the Weaver River (UK) did not result in systematically better model performance which highlights the complexity of model

  5. Wave model downscaling for coastal applications

    NASA Astrophysics Data System (ADS)

    Valchev, Nikolay; Davidan, Georgi; Trifonova, Ekaterina; Andreeva, Nataliya

    2010-05-01

    Downscaling is a suitable technique for obtaining high-resolution estimates from relatively coarse-resolution global models. Dynamical and statistical downscaling has been applied to the multidecadal simulations of ocean waves. Even as large-scale variability might be plausibly estimated from these simulations, their value for the small scale applications such as design of coastal protection structures and coastal risk assessment is limited due to their relatively coarse spatial and temporal resolutions. Another advantage of the high resolution wave modeling is that it accounts for shallow water effects. Therefore, it can be used for both wave forecasting at specific coastal locations and engineering applications that require knowledge about extreme wave statistics at or near the coastal facilities. In the present study downscaling is applied to both ECMWF and NCEP/NCAR global reanalysis of atmospheric pressure over the Black Sea with 2.5 degrees spatial resolution. A simplified regional atmospheric model is employed for calculation of the surface wind field at 0.5 degrees resolution that serves as forcing for the wave models. Further, a high-resolution nested WAM/SWAN wave model suite of nested wave models is applied for spatial downscaling. It aims at resolving the wave conditions in a limited area at the close proximity to the shore. The pilot site is located in the northern part the Bulgarian Black Sea shore. The system involves the WAM wave model adapted for basin scale simulation at 0.5 degrees spatial resolution. The WAM output for significant wave height, mean wave period and mean angle of wave approach is used in terms of external boundary conditions for the SWAN wave model, which is set up for the western Black Sea shelf at 4km resolution. The same model set up on about 400m resolution is nested to the first SWAN run. In this case the SWAN 2D spectral output provides boundary conditions for the high-resolution model run. The models are implemented for a

  6. An integrated system for nonpoint source pollution modelling and management.

    PubMed

    Zhang, D; Chen, J; Du, P; He, W

    2006-01-01

    Modelling the impact of nonpoint source pollution (NSP) is a complex problem that has troubled water resource managers for many years when trying to set up proper management practices in catchment areas. In this paper, an integrated decision support system, NPSDSS (nonpoint source decision support system), was introduced to resolve this problem in a relatively easy way. The system was developed in a unique platform and integrated with the IMPULSE (integrated model of nonpoint source pollution processes) model, a stand alone geographic information system (GIS) toolbox, a well-structured database, a measure screening model, and an expert system, as well. The system has been applied in the Dianchi Lake catchment area and shown to give a good perspective on providing useful recommendations for appropriate NSP management.

  7. Numerical Modelling of Drawbeads for Forming of Aluminium Alloys

    NASA Astrophysics Data System (ADS)

    Joshi, Y.; Christiansen, P.; Masters, I.; Bay, N.; Dashwood, R.

    2016-08-01

    The drawbeads in stamping tools are usually designed based on experience from the forming of steel. However, aluminium alloys display different forming behaviour to steels, which is not reflected in the drawbead design for tools used for stamping aluminium. This paper presents experimental results from different semi-circular drawbead geometries commonly encountered in automotive dies and compares them to those obtained from Stoughton's analytical drawbead model and the 2D plane strain drawbead model set up using LS-DYNA. The study was conducted on lubricated NG5754 strips. The results presented are in terms of drawbead restraining force versus strip displacement, as a function of drawbead depth. The FE drawbead model agrees well with the experiments whereas the analytical model overpredicted the drawbead forces.

  8. Applying simulation and logistics modeling to tansportation issues

    SciTech Connect

    Funkhouser, B.R.; Ballweg, E.L.; Mackoy, R.D.

    1995-08-15

    This paper describes an application where transportation logistics and simulation tools are integrated to create a modeling environment for transportation planning. The Transportation Planning Model (TPM) is a tool developed for the Department of Energy (DOE) to aid in the long-term planning of their transportation resources. The focus of the tool is to aid DOE and Sandia National Laboratory analysts in the planning of future fleet sizes, driver and support personnel sizes, base site locations, and resource balancing among the base sites. The design approach is to develop a rapid modeling environment which integrates graphical user interfaces, logistics optimizing tools, and simulation modeling. Using the TPM an analyst can easily set up a shipment scenario and perform multiple ``What If`` evaluations. The TPM has been developed on personal computers using commercial off-the-shelf software tools under the WINDOW{reg_sign} operating environment.

  9. GENERIC MODEL FOR MAGNETIC EXPLOSIONS APPLIED TO SOLAR FLARES

    SciTech Connect

    Melrose, D. B.

    2012-04-10

    An accepted model for magnetospheric substorms is proposed as the basis for a generic model for magnetic explosions and is applied to solar flares. The model involves widely separated energy-release and particle-acceleration regions, with energy transported Alfvenically between them. On a global scale, these regions are coupled by a large-scale current that is set up during the explosion by redirection of pre-existing current associated with the stored magnetic energy. The explosion-related current is driven by an electromotive force (EMF) due to the changing magnetic flux enclosed by this current. The current path and the EMF are identified for an idealized quadrupolar model for a flare.

  10. Development and testing of a distributed urban storm runoff event model with a vector-based catchment delineation

    NASA Astrophysics Data System (ADS)

    Amaguchi, H.; Kawamura, A.; Olsson, J.; Takasaki, T.

    2012-02-01

    SummaryThe recent advances in GIS technology as well as data availability open up new possibilities concerning urban storm runoff modeling. In this paper, a vector-based distributed storm event runoff model - the Tokyo Storm Runoff (TSR) model - is developed and tested for urban runoff analysis using two historical storm events. The set-up of this model is based on urban landscape GIS delineation that faithfully describes the complicated urban land use features in detail. The flow between single spatial elements is based on established hydraulic and hydrological models with equations that describe all aspects of storm runoff generation in an urban environment. The model was set up and evaluated for the small urban lower Ekota catchment in Tokyo Metropolis, Japan. No calibration or tuning was performed, but the general model formulation was used with standard parameter values obtained from the literature. The runoff response to two storm events were simulated; one minor event resulting only in a small-scale flood wave and one major event which inundated parts of the catchment. For both events, the simulated water levels closely reproduced the observed ones. For the major event, also the reported inundation area was well described by the model. It was also demonstrated how the model can be used to evaluate the flow conditions in specific components of the urban hydrological system, which facilitates e.g. evaluation of flood-preventive measures.

  11. Bayesian spatio-temporal random coefficient time series (BaST-RCTS) model of infectious disease.

    PubMed

    Zhang, Tao; Zhang, Xingyu; Ma, Yue; Zhou, Xiaohua Andrew; Liu, Yuanyuan; Feng, Zijian; Li, Xiaosong

    2014-12-01

    This paper proposes a new method, using Bayesian approach, to analyze time series data of infectious diseases which have both temporal and spatial variational structures. Standard ways to model heteroscedastic time series are the ARCH-type models. However, from an empirical standpoint, there is a need to include spatial effect into time series analysis to make allowance for confounder and ecological biases. On the basis of random coefficient autoregressive model, our model takes account of spatial correlated/uncorrelated heterogeneity. To assure the applicability of our model, we set up hypothesis framework before analyzing. It was proved that our model could provide the first two conditional moments of ARCH-type models. The empirical study of bacillary dysentery data also illustrated that our model could make accurate and precise approximations.

  12. Modeling study of the ABS relay valve

    NASA Astrophysics Data System (ADS)

    Lei, Ming; Lin, Min; Guo, Bin; Luo, Zai; Xu, Weidong

    2011-05-01

    The ABS (anti-lock braking system) relay valve is the key component of anti-lock braking system in most commercial vehicles such as trucks, tractor-trailers, etc. In this paper, structure of ABS relay valve and its work theory were analyzed. Then a mathematical model of ABS relay valve, which was investigated by dividing into electronic part, magnetic part, pneumatic part and mechanical part, was set up. The displacement of spools and the response of pressure increasing, holding, releasing of ABS relay valve were simulated and analyzed under conditions of control pressure 500 KPa, braking pressure 600 KPa, atmospheric pressure 100 KPa and air temperature 310 K. Thisarticle provides reliable theory for improving the performance and efficiency of anti-lock braking system of vehicles.

  13. Modeling study of the ABS relay valve

    NASA Astrophysics Data System (ADS)

    Lei, Ming; Lin, Min; Guo, Bin; Luo, Zai; Xu, Weidong

    2010-12-01

    The ABS (anti-lock braking system) relay valve is the key component of anti-lock braking system in most commercial vehicles such as trucks, tractor-trailers, etc. In this paper, structure of ABS relay valve and its work theory were analyzed. Then a mathematical model of ABS relay valve, which was investigated by dividing into electronic part, magnetic part, pneumatic part and mechanical part, was set up. The displacement of spools and the response of pressure increasing, holding, releasing of ABS relay valve were simulated and analyzed under conditions of control pressure 500 KPa, braking pressure 600 KPa, atmospheric pressure 100 KPa and air temperature 310 K. Thisarticle provides reliable theory for improving the performance and efficiency of anti-lock braking system of vehicles.

  14. First principles cable braid electromagnetic penetration model

    SciTech Connect

    Warne, Larry Kevin; Langston, William L.; Basilio, Lorena I.; Johnson, William A.

    2016-01-01

    The model for penetration of a wire braid is rigorously formulated. Integral formulas are developed from energy principles for both self and transfer immittances in terms of potentials for the fields. The detailed boundary value problem for the wire braid is also set up in a very efficient manner; the braid wires act as sources for the potentials in the form of a sequence of line multi-poles with unknown coefficients that are determined by means of conditions arising from the wire surface boundary conditions. Approximations are introduced to relate the local properties of the braid wires to a simplified infinite periodic planar geometry. Furthermore, this is used to treat nonuniform coaxial geometries including eccentric interior coaxial arrangements and an exterior ground plane.

  15. First principles cable braid electromagnetic penetration model

    DOE PAGES

    Warne, Larry Kevin; Langston, William L.; Basilio, Lorena I.; Johnson, William A.

    2016-01-01

    The model for penetration of a wire braid is rigorously formulated. Integral formulas are developed from energy principles for both self and transfer immittances in terms of potentials for the fields. The detailed boundary value problem for the wire braid is also set up in a very efficient manner; the braid wires act as sources for the potentials in the form of a sequence of line multi-poles with unknown coefficients that are determined by means of conditions arising from the wire surface boundary conditions. Approximations are introduced to relate the local properties of the braid wires to a simplified infinitemore » periodic planar geometry. Furthermore, this is used to treat nonuniform coaxial geometries including eccentric interior coaxial arrangements and an exterior ground plane.« less

  16. Aging mechanism in model Pickering emulsion

    NASA Astrophysics Data System (ADS)

    Fouilloux, Sarah; Malloggi, Florent; Daillant, Jean; Thill, Antoine

    We study the stability of a model Pickering emulsion system. A special counter-flow microfluidics set-up was used to prepare monodisperse Pickering emulsions, with oil droplets in water. The wettability of the monodisperse silica nanoparticles (NPs) could be tuned by surface grafting and the surface coverage of the droplets was controlled using the microfluidics setup. A surface coverage as low as 23$\\%$ is enough to stabilize the emulsions and we evidence a new regime of Pickering emulsion stability where the surface coverage of emulsion droplets of constant size increases in time, in coexistence with a large amount of dispersed phase. Our results demonstrate that the previously observed limited coalescence regime where surface coverage tends to control the average size of the final droplets must be put in a broader perspective.

  17. Hydrological modeling in alpine catchments: sensing the critical parameters towards an efficient model calibration.

    PubMed

    Achleitner, S; Rinderer, M; Kirnbauer, R

    2009-01-01

    For the Tyrolean part of the river Inn, a hybrid model for flood forecast has been set up and is currently in its test phase. The system is a hybrid system which comprises of a hydraulic 1D model for the river Inn, and the hydrological models HQsim (Rainfall-runoff-discharge model) and the snow and ice melt model SES for modeling the rainfall runoff form non-glaciated and glaciated tributary catchment respectively. Within this paper the focus is put on the hydrological modeling of the totally 49 connected non-glaciated catchments realized with the software HQsim. In the course of model calibration, the identification of the most sensitive parameters is important aiming at an efficient calibration procedure. The indicators used for explaining the parameter sensitivities were chosen specifically for the purpose of flood forecasting. Finally five model parameters could be identified as being sensitive for model calibration when aiming for a well calibrated model for flood conditions. In addition two parameters were identified which are sensitive in situations where the snow line plays an important role.

  18. Hydrological modeling in alpine catchments: sensing the critical parameters towards an efficient model calibration.

    PubMed

    Achleitner, S; Rinderer, M; Kirnbauer, R

    2009-01-01

    For the Tyrolean part of the river Inn, a hybrid model for flood forecast has been set up and is currently in its test phase. The system is a hybrid system which comprises of a hydraulic 1D model for the river Inn, and the hydrological models HQsim (Rainfall-runoff-discharge model) and the snow and ice melt model SES for modeling the rainfall runoff form non-glaciated and glaciated tributary catchment respectively. Within this paper the focus is put on the hydrological modeling of the totally 49 connected non-glaciated catchments realized with the software HQsim. In the course of model calibration, the identification of the most sensitive parameters is important aiming at an efficient calibration procedure. The indicators used for explaining the parameter sensitivities were chosen specifically for the purpose of flood forecasting. Finally five model parameters could be identified as being sensitive for model calibration when aiming for a well calibrated model for flood conditions. In addition two parameters were identified which are sensitive in situations where the snow line plays an important role. PMID:19759453

  19. The correction of the distortion of human face based on three-dimensional modeling methods

    NASA Astrophysics Data System (ADS)

    Ye, Qingmin; Chen, Kuo; Feng, Huajun; Xu, Zhihai; Li, Qi

    2015-08-01

    When the human face is on the edge of field of the camera which has a large view, serious deformation will be captured. To correct the distortion of the human face, we present an approach based on setting up a 3D model. Firstly, we construct 3D target face modeling by using the data and depth information of the standard human face, which is set up by the three-dimensional model with three-dimensional Gaussian function with sectional type. According to the size of the face in the image and the parameters of the camera, we can obtain the information of relative position and depth of the human face. Then by translating the virtual camera axis to the center of the face, we can achieve the goal to correct the distortion of the face based on the theory of three-dimensional imaging. Finally, we have made a lot of experiments, and we study the influence of parameters of the 3D model of human face. The result indicates that the method presented by this paper can play an effective role in correcting the distortion of the face in the edge of the view, and we can get better results if the model appreciates the real human face.

  20. An EMTP system level model of the PMAD DC test bed

    NASA Technical Reports Server (NTRS)

    Dravid, Narayan V.; Kacpura, Thomas J.; Tam, Kwa-Sur

    1991-01-01

    A power management and distribution direct current (PMAD DC) test bed was set up at the NASA Lewis Research Center to investigate Space Station Freedom Electric Power Systems issues. Efficiency of test bed operation significantly improves with a computer simulation model of the test bed as an adjunct tool of investigation. Such a model is developed using the Electromagnetic Transients Program (EMTP) and is available to the test bed developers and experimenters. The computer model is assembled on a modular basis. Device models of different types can be incorporated into the system model with only a few lines of code. A library of the various model types is created for this purpose. Simulation results and corresponding test bed results are presented to demonstrate model validity.

  1. ADM Analysis of gravity models within the framework of bimetric variational formalism

    SciTech Connect

    Golovnev, Alexey; Karčiauskas, Mindaugas; Nyrhinen, Hannu J. E-mail: mindaugas.karciauskas@helsinki.fi

    2015-05-01

    Bimetric variational formalism was recently employed to construct novel bimetric gravity models. In these models an affine connection is generated by an additional tensor field which is independent of the physical metric. In this work we demonstrate how the ADM decomposition can be applied to study such models and provide some technical intermediate details. Using ADM decomposition we are able to prove that a linear model is unstable as has previously been indicated by perturbative analysis. Moreover, we show that it is also very difficult if not impossible to construct a non-linear model which is ghost-free within the framework of bimetric variational formalism. However, we demonstrate that viable models are possible along similar lines of thought. To this end, we consider a set up in which the affine connection is a variation of the Levi-Civita one. As a proof of principle we construct a gravity model with a massless scalar field obtained this way.

  2. Java Web Simulation (JWS); a web based database of kinetic models.

    PubMed

    Snoep, J L; Olivier, B G

    2002-01-01

    Software to make a database of kinetic models accessible via the internet has been developed and a core database has been set up at http://jjj.biochem.sun.ac.za/. This repository of models, available to everyone with internet access, opens a whole new way in which we can make our models public. Via the database, a user can change enzyme parameters and run time simulations or steady state analyses. The interface is user friendly and no additional software is necessary. The database currently contains 10 models, but since the generation of the program code to include new models has largely been automated the addition of new models is straightforward and people are invited to submit their models to be included in the database.

  3. Simiyu River catchment parameterization using SWAT model

    NASA Astrophysics Data System (ADS)

    Mulungu, Deogratias M. M.; Munishi, Subira E.

    The paper presents advances in hydrologic modelling of the Simiyu River catchment using the soil and water assessment tool (SWAT). In this study, the SWAT model set-up and subsequent application to the catchment was based on high-resolution data such as land use from 30 m LandSat TM Satellite, 90 m Digital Elevation Model and Soil from Soil and Terrain Database for Southern Africa (SOTERSAF). The land use data were reclassified based on some ground truth maps using IDRISI Kilimanjaro software. The Soil data were also reclassified manually to represent different soil hydrologic groups, which are important for the SWAT model set-up and simulations. The SWAT application first involved analysis of parameter sensitivity, which was then used for model auto-calibration that followed hierarchy of sensitive model parameters. The analysis of sensitive parameters and auto-calibration was achieved by sensitivity analysis and auto-calibration options, which are new in the recent version of SWAT, SWAT 2005. The paper discusses the results of sensitivity and auto-calibration analyses, and present optimum model parameters, which are important for operation and water/land management studies (e.g. rain-fed agriculture and erosion/sediment and pollutant transport) in the catchment using SWAT. The river discharge estimates from this and a previous study were compared so as to evaluate performances of the recent hydrologic simulations in the catchment. Results showed that surface water model parameters are the most sensitive and have more physical meaning especially CN2 (the most sensitive) and SOL_K. Simulation results showed more or less same estimate of river flow at Ndagalu gauging station. The model efficiencies ( R2%) in this and in the pervious study during calibration and validation periods were, respectively, 13.73, 14.22 and 40.54, 36.17. The low level of model performance achieved in these studies showed that other factors than the spatial land data are greatly important for

  4. Simple analytical model of evapotranspiration in the presence of roots

    NASA Astrophysics Data System (ADS)

    Cejas, Cesare; Castaing, Jean-Christophe; Hough, Larry; Fretigny, Christian; Dreyfus, Remi; Compass Team

    2015-03-01

    Water is essential for plant growth. The loss of water via evaporation in soil remains to be an important limiting factor for root growth and consists of well-debated mechanisms. The presence of a plant also provides an additional pathway for water transport in the form of transpiration. Prediction of total evapotranspiration flux permits estimation of the remaining quantity of water in the soil. Using a controlled visual 2D model set-up, we perform evaporation experiments with real root systems under different relative humidity conditions. We use the results on mass loss and evaporation front positions to develop a simple model, based on basic principles of evaporation flux, which predicts the position of the evaporating front and the total mass of water that is lost from the evapotranspiration of water out of the granular medium. The model also helps predict the lifetime of the plant - an important application in agriculture.

  5. Membrane set up combined with photoionization-ion mobility spectrometer to improve analytical performance and avoid humidity interference on the determination of aromatics in gaseous samples.

    PubMed

    Criado-García, L; Arce, L; Valcárcel, M

    2016-01-29

    UV-ion mobility spectrometry (UV-IMS) is a reliable and inexpensive technique which allows efficient monitoring of BTX (benzene, toluene, m-xylene, o-xylene and p-xylene) in different air samples. Water molecules are unavoidably present in every on-field measurement affecting sensitivity and selectivity of the UV-IMS method. For this reason, the influence of humidity on the mobility spectra when measuring BTX is discussed here. Furthermore, a polydimethyl siloxane (PDMS) membrane assembled on an ad-hoc designed membrane holder coupled to UV-IMS was proposed for online measurement of analytes in humid gaseous samples without sample preparation/pre-treatment steps. The use of this membrane reduces the moisture of the gaseous sample before entering into the IMS, and the consequent distortion of the signal. The limit of detection (LOD) and the limit of quantification (LOQ) achieved with the method proposed were in the range of 0.49-1.21mgL(-1) and 1.63-4.03mgL(-1), respectively for all analytes. The precision of the method was evaluated in terms of repeatability and reproducibility obtaining values lower than 1.1% for drift time and 12.0% for peak height when the membrane was used coupled to the UV-IMS for all target analytes in the humidity range of 10-75% RH. Thus, BTX can be determined directly and quantified unequivocally with the membrane system in ambient air even at humid condition.

  6. Bis-methionyl Coordination in the Crystal Structure of the Set up a citation RSS feed (Opens new window) Citation Feed

    SciTech Connect

    Aranda IV, Roman; Worley, Chad E.; Liu, Mengyao; Bitto, Eduard; Cates, M. Susan; Olson, John S.; Lei, Benfang; Phillips, Jr., George N.

    2010-01-07

    Surface proteins Shr, Shp, and the ATP-binding cassette (ABC) transporter HtsABC are believed to make up the machinery for heme uptake in Streptococcus pyogenes. Shp transfers its heme to HtsA, the lipoprotein component of HtsABC, providing the only experimentally demonstrated example of direct heme transfer from a surface protein to an ABC transporter in Gram-positive bacteria. To understand the structural basis of heme transfer in this system, the heme-binding domain of Shp (Shp{sup 180}) was crystallized, and its structure determined to a resolution of 2.1 {angstrom}. Shp{sup 180} exhibits an immunoglobulin-like {beta}-sandwich fold that has been recently found in other pathogenic bacterial cell surface heme-binding proteins, suggesting that the mechanisms of heme acquisition are conserved. Shp shows minimal amino acid sequence identity to these heme-binding proteins and the structure of Shp{sup 180} reveals a unique heme-iron coordination with the axial ligands being two methionine residues from the same Shp molecule. A negative electrostatic surface of protein structure surrounding the heme pocket may serve as a docking interface for heme transfer from the more basic outer cell wall heme receptor protein Shr. The crystal structure of Shp{sup 180} reveals two exogenous, weakly bound hemins, which form a large interface between the two Shp{sup 180} molecules in the asymmetric unit. These 'extra' hemins form a stacked pair with a structure similar to that observed previously for free hemin dimers in aqueous solution. The propionates of the protein-bound heme coordinate to the iron atoms of the exogenous hemin dimer, contributing to the stability of the protein interface. Gel filtration and analytical ultracentrifugation studies indicate that both full-length Shp and Shp{sup 180} are monomeric in dilute aqueous solution.

  7. An experiment proposed and set up by the readers will be flying on board the Shuttle; these are the rules of the game; the experiments of others

    NASA Technical Reports Server (NTRS)

    Pazzano, P.; Masini, G.

    1982-01-01

    The 400th round trip ticket to space via the space shuttle is booked in the name of an Italian journal. Students from that country are offered an opportunity to propose an experiment for NASA's Get Away Special program. The dimensional characteristics of the container, as specified by NASA, are given as well as limitations of weight, volume, diameter, and height for the experiment. The types of experiments in the OSS-1 payload and their operation are described.

  8. An Optimized Table-Top Small-Angle X-ray Scattering Set-up for the Nanoscale Structural Analysis of Soft Matter

    NASA Astrophysics Data System (ADS)

    Sibillano, T.; de Caro, L.; Altamura, D.; Siliqi, D.; Ramella, M.; Boccafoschi, F.; Ciasca, G.; Campi, G.; Tirinato, L.; di Fabrizio, E.; Giannini, C.

    2014-11-01

    The paper shows how a table top superbright microfocus laboratory X-ray source and an innovative restoring-data algorithm, used in combination, allow to analyze the super molecular structure of soft matter by means of Small Angle X-ray Scattering ex-situ experiments. The proposed theoretical approach is aimed to restore diffraction features from SAXS profiles collected from low scattering biomaterials or soft tissues, and therefore to deal with extremely noisy diffraction SAXS profiles/maps. As biological test cases we inspected: i) residues of exosomes' drops from healthy epithelial colon cell line and colorectal cancer cells; ii) collagen/human elastin artificial scaffolds developed for vascular tissue engineering applications; iii) apoferritin protein in solution. Our results show how this combination can provide morphological/structural nanoscale information to characterize new artificial biomaterials and/or to get insight into the transition between healthy and pathological tissues during the progression of a disease, or to morphologically characterize nanoscale proteins, based on SAXS data collected in a room-sized laboratory.

  9. Set-up of an infrared fast behavioral assay using zebrafish (Danio rerio) larvae, and its application in compound biotoxicity screening.

    PubMed

    Bichara, Darío; Calcaterra, Nora B; Arranz, Silvia; Armas, Pablo; Simonetta, Sergio H

    2014-02-01

    Zebrafish (Danio rerio) is increasingly employed for evaluating toxicity and drug discovery assays. Commonly experimental approaches for biotoxicity assessment are based on visual inspection or video recording. However, these techniques are limited for large-scale assays, as they demand either a time-consuming detailed inspection of the animals or intensive computing resources in order to analyze a considerable amount of screenshots. Recently, we have developed a simple methodology for tracking the locomotor activity of small animals cultured in microtiter plates. In this work, we implemented this automatic methodology, based on infrared (IR) microbeam scattering, for measuring behavioral activity in zebrafish larvae. We determined the appropriate culture conditions, number of animals and stage of development to get robust results. Furthermore, we validated this methodology as a rapid test for evaluating toxicity. By measuring the effects of reference compounds on larvae activity, we were able to estimate the concentration that could cause a 50% decrease in activity events values (AEC₅₀), showing a strong linear correlation (R²  = 0.91) with the LC₅₀ values obtained with the standard DarT test. The toxicity order of the measured compounds was CuSO4  > 2,4-dinitrophenol > 3,4-dichloroaniline > SDS > sodium benzoate > EDTA > K₂CrO4 ; regarding solvents, EtOH ≈ DMSO. In this study, we demonstrate that global swimming behavior could be a simple readout for toxicity, easy to scale-up in automated experiments. This approach is potentially applicable for fast ecotoxicity assays and whole-organism high-throughput compound screening, reducing the time and money required to evaluate unknown samples and to identify leading pharmaceutical compounds. PMID:23401233

  10. Pitfalls and Challenges to Consider before Setting up a Lung Cancer Intensity-modulated Radiotherapy Service: A Review of the Reported Clinical Experience.

    PubMed

    Shrimali, R K; Mahata, A; Reddy, G D; Franks, K N; Chatterjee, S

    2016-03-01

    Intensity-modulated radiotherapy (IMRT) is being increasingly used for the treatment of non-small cell lung cancer (NSCLC), despite the absence of published randomised controlled trials. Planning studies and retrospective series have shown a decrease in known predictors of lung toxicity (V20 and mean lung dose) and the maximum spinal cord dose. Potential dosimetric advantages, accessibility of technology, a desire to escalate dose or a need to meet normal organ dose constraints are some of the factors recognised as supporting the use of IMRT. However, IMRT may not be appropriate for all patients being treated with radical radiotherapy. Unique problems with using IMRT for NSCLC include organ and tumour motion because of breathing and the potential toxicity from low doses of radiotherapy to larger amounts of lung tissue. Caution should be exercised as there is a paucity of prospective data regarding the efficacy and safety of IMRT in lung cancer when compared with three-dimensional conformal radiotherapy and IMRT data from other cancer sites should not be extrapolated. This review looks at the use of IMRT in NSCLC, addresses the challenges and highlights the potential benefits of using this complex radiotherapy technique.

  11. Impact of Specialist Home-Based Palliative Care Services in a Tertiary Oncology Set Up: A Prospective Non-Randomized Observational Study

    PubMed Central

    Dhiliwal, Sunil R; Muckaden, Maryann

    2015-01-01

    Background: Home-based specialist palliative care services are developed to meet the needs of the patients in advanced stage of cancer at home with physical symptoms and distress. Specialist home care services are intended to improve symptom control and quality of life, enable patients to stay at home, and avoid unnecessary hospital admission. Materials and Methods: Total 690 new cases registered under home-based palliative care service in the year 2012 were prospectively studied to assess the impact of specialist home-based services using Edmonton symptom assessment scale (ESAS) and other parameters. Results: Out of the 690 registered cases, 506 patients received home-based palliative care. 50.98% patients were cared for at home, 28.85% patients needed hospice referral and 20.15% patients needed brief period of hospitalization. All patients receiving specialist home care had good relief of physical symptoms (P < 0.005). 83.2% patients received out of hours care (OOH) through liaising with local general practitioners; 42.68% received home based bereavement care and 91.66% had good bereavement outcomes. Conclusion: Specialist home-based palliative care improved symptom control, health-related communication and psychosocial support. It promoted increased number of home-based death, appropriate and early hospice referral, and averted needless hospitalization. It improved bereavement outcomes, and caregiver satisfaction. PMID:25709182

  12. Laser-Assisted Bending of Sharp Angles With Small Fillet Radius on Stainless Steel Sheets: Analysis of Experimental Set-Up and Processing Parameters

    NASA Astrophysics Data System (ADS)

    Gisario, Annamaria; Barletta, Massimiliano; Venettacci, Simone; Veniali, Francesco

    2015-06-01

    Achievement of sharp bending angles with small fillet radius on stainless steel sheets by mechanical bending requires sophisticated bending device and troublesome operational procedures, which can involve expensive molds, huge presses and large loads. In addition, springback is always difficult to control, thus often leading to final parts with limited precision and accuracy. In contrast, laser-assisted bending of metals is an emerging technology, as it often allows to perform difficult and multifaceted manufacturing tasks with relatively small efforts. In the present work, laser-assisted bending of stainless steel sheets to achieve sharp angles is thus investigated. First, bending trials were performed by combining laser irradiation with an auxiliary bending device triggered by a pneumatic actuator and based on kinematic of deformable quadrilaterals. Second, laser operational parameters, that is, scanning speed, power and number of passes, were varied to identify the most suitable processing settings. Bending angles and fillet radii were measured by coordinate measurement machine. Experimental data were elaborated by combined ANalysis Of Mean (ANOM) and ANalysis Of VAriance (ANOVA). Based on experimental findings, the best strategy to achieve an aircraft prototype from a stainless steel sheet was designed and implemented.

  13. Set-up of a high-resolution 300 mK atomic force microscope in an ultra-high vacuum compatible (3)He/10 T cryostat.

    PubMed

    von Allwörden, H; Ruschmeier, K; Köhler, A; Eelbo, T; Schwarz, A; Wiesendanger, R

    2016-07-01

    The design of an atomic force microscope with an all-fiber interferometric detection scheme capable of atomic resolution at about 500 mK is presented. The microscope body is connected to a small pumped (3)He reservoir with a base temperature of about 300 mK. The bakeable insert with the cooling stage can be moved from its measurement position inside the bore of a superconducting 10 T magnet into an ultra-high vacuum chamber, where the tip and sample can be exchanged in situ. Moreover, single atoms or molecules can be evaporated onto a cold substrate located inside the microscope. Two side chambers are equipped with standard surface preparation and surface analysis tools. The performance of the microscope at low temperatures is demonstrated by resolving single Co atoms on Mn/W(110) and by showing atomic resolution on NaCl(001). PMID:27475560

  14. Set-up of a high-resolution 300 mK atomic force microscope in an ultra-high vacuum compatible 3He/10 T cryostat

    NASA Astrophysics Data System (ADS)

    von Allwörden, H.; Ruschmeier, K.; Köhler, A.; Eelbo, T.; Schwarz, A.; Wiesendanger, R.

    2016-07-01

    The design of an atomic force microscope with an all-fiber interferometric detection scheme capable of atomic resolution at about 500 mK is presented. The microscope body is connected to a small pumped 3He reservoir with a base temperature of about 300 mK. The bakeable insert with the cooling stage can be moved from its measurement position inside the bore of a superconducting 10 T magnet into an ultra-high vacuum chamber, where the tip and sample can be exchanged in situ. Moreover, single atoms or molecules can be evaporated onto a cold substrate located inside the microscope. Two side chambers are equipped with standard surface preparation and surface analysis tools. The performance of the microscope at low temperatures is demonstrated by resolving single Co atoms on Mn/W(110) and by showing atomic resolution on NaCl(001).

  15. 7 CFR Exhibit J to Subpart A of... - Manufactured Home Sites, Rental Projects and Subdivisions: Development, Installation and Set-Up

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...: 1. Federal Manufactured Home Construction and Safety Standards, 24 CFR part 3280, mandated by... of part 1940, “Environmental Program.” 4. 7 CFR part 3550, “Direct Single Family Housing Loans and... manufactured home lots (scattered sites and subdivision) shall be determined by 7 CFR part 3550 and subpart...

  16. 7 CFR Exhibit J to Subpart A of... - Manufactured Home Sites, Rental Projects and Subdivisions: Development, Installation and Set-Up

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...: 1. Federal Manufactured Home Construction and Safety Standards, 24 CFR part 3280, mandated by... of part 1940, “Environmental Program.” 4. 7 CFR part 3550, “Direct Single Family Housing Loans and... manufactured home lots (scattered sites and subdivision) shall be determined by 7 CFR part 3550 and subpart...

  17. 7 CFR Exhibit J to Subpart A of... - Manufactured Home Sites, Rental Projects and Subdivisions: Development, Installation and Set-Up

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...: 1. Federal Manufactured Home Construction and Safety Standards, 24 CFR part 3280, mandated by... of part 1940, “Environmental Program.” 4. 7 CFR part 3550, “Direct Single Family Housing Loans and... manufactured home lots (scattered sites and subdivision) shall be determined by 7 CFR part 3550 and subpart...

  18. Set-up and calibration of an outdoor nozzle-type rainfall simulator for soil erosion studies at the Masse experimental station (central Italy)

    NASA Astrophysics Data System (ADS)

    Vergni, Lorenzo; Todisco, Francesca

    2016-04-01

    This contribution describes the technical characteristics and the preliminary calibration of a rainfall simulator recently installed by the Department of Agricultural, Food and Environmental Sciences (Perugia University) at the Masse experimental station located 20 km south of Perugia, in the region of Umbria (central Italy). The site includes some USLE plots of different length λ = 11 and 22 m and width w = 2, 4 and 8 m, oriented parallel to a 16 % slope and kept free of vegetation by frequent ploughing. Since 2008, the station enabled to collect data from more than 80 erosive events, that were mainly used to investigate the relationship between rainfall characteristics and soil loss. The relevant soil loss variability that characterizes erosive storm events with similar overall characteristics (duration and/or depth) can be explained by the different rainfall profile of erosive storms and by the different antecedent soil aggregate stability. To analyse in more detail these aspects, recently, the Masse experimental station has been equipped with a semi-portable rainfall simulator placed over two micro-plots of 1x1 m each, having the same topographic and pedologic conditions of the adjacent USLE plots. The rainfall simulator consists of four full-cone spray nozzles for each micro-plot, placed at the angles of a 0.18-m square, centred over the plot at a height of 2.7 m above the ground. The operating pressure is regulated by pressure regulating valves and checked by pressure gauges mounted in correspondence of each nozzle. An electronic control unit regulates the start and stop of the inlet solenoid valves. A range of rainfall intensities can be achieved, by activating different combinations of nozzles (15 different intensities) also during the same simulation trial. The particular design of the plots allows to collect separately the runoff volume deriving from the plots and the water volume fallen outside of the plot. In this way it is possible to derive, by difference, the actual infiltration volume. The experiments are carried out simultaneously on the two adjacent micro-plots. In particular, this contribution reports the results of the first experimental trials aimed to assess the uniformity attainable by single nozzles and its reproducibility (between plots and in time). The interferences between adjacent nozzles (when they work simultaneously) were also evaluated.

  19. A comprehensive dose evaluation project concerning animals affected by the Fukushima Daiichi Nuclear Power Plant accident: its set-up and progress

    PubMed Central

    Takahashi, Shintaro; Inoue, Kazuya; Suzuki, Masatoshi; Urushihara, Yusuke; Kuwahara, Yoshikazu; Hayashi, Gohei; Shiga, Soichiro; Fukumoto, Motoi; Kino, Yasushi; Sekine, Tsutomu; Abe, Yasuyuki; Fukuda, Tomokazu; Isogai, Emiko; Yamashiro, Hideaki; Fukumoto, Manabu

    2015-01-01

    It is not an exaggeration to say that, without nuclear accidents or the analysis of radiation therapy, there is no way in which we are able to quantify radiation effects on humans. Therefore, the livestock abandoned in the ex-evacuation zone and euthanized due to the Fukushima Daiichi Nuclear Power Plant (FNPP) accident are extremely valuable for analyzing the environmental pollution, its biodistribution, the metabolism of radionuclides, dose evaluation and the influence of internal exposure. We, therefore, sought to establish an archive system and to open it to researchers for increasing our understanding of radiation biology and improving protection against radiation. The sample bank of animals affected by the FNPP accident consists of frozen tissue samples, formalin-fixed paraffin-embedded specimens, dose of radionuclides deposited, etc., with individual sampling data. PMID:26687285

  20. Documentation and Instructions for Running Two Python Scripts that Aid in Setting up 3D Measurements using the Polytec 3D Scanning Laser Doppler Vibrometer.

    SciTech Connect

    Rohe, Daniel Peter

    2015-08-24

    Sandia National Laboratories has recently purchased a Polytec 3D Scanning Laser Doppler Vibrometer for vibration measurement. This device has proven to be a very nice tool for making vibration measurements, and has a number of advantages over traditional sensors such as accelerometers. The non-contact nature of the laser vibrometer means there is no mass loading due to measuring the response. Additionally, the laser scanning heads can position the laser spot much more quickly and accurately than placing an accelerometer or performing a roving hammer impact. The disadvantage of the system is that a significant amount of time must be invested to align the lasers with each other and the part so that the laser spots can be accurately positioned. The Polytec software includes a number of nice tools to aid in this procedure; however, certain portions are still tedious. Luckily, the Polytec software is readily extensible by programming macros for the system, so tedious portions of the procedure can be made easier by automating the process. The Polytec Software includes a WinWrap (similar to Visual Basic) editor and interface to run macros written in that programming language. The author, however, is much more proficient in Python, and the latter also has a much larger set of libraries that can be used to create very complex macros, while taking advantage of Python’s inherent readability and maintainability.

  1. Adoptive T-cell immunotherapy from third-party donors: characterization of donors and set up of a T-cell donor registry

    PubMed Central

    Eiz-Vesper, Britta; Maecker-Kolhoff, Britta; Blasczyk, Rainer

    2013-01-01

    Infection with and reactivation of human cytomegalovirus (CMV), Epstein-Barr virus (EBV), and adenovirus (ADV) are frequent and severe complications in immunocompromised recipients after hematopoietic stem cell transplantation (HSCT) or solid organ transplantation (SOT). These serious adverse events are associated with significant morbidity and mortality. Donor lymphocyte infusions (DLIs) are often used to treat both viral infections and leukemia relapses after transplantation but are associated with potentially life-threatening graft-versus-host disease (GvHD). Adoptive immunotherapy with virus-specific cytotoxic effector T cells (CTLs) derived from seropositive donors can rapidly reconstitute antiviral immunity after HSCT and organ transplantation. Therefore, it can effectively prevent the clinical manifestation of these viruses with no significant acute toxicity or increased risk of GvHD. In conditions, where patients receiving an allogeneic cord blood (CB) transplant or a transplant from a virus-seronegative donor and since donor blood is generally not available for solid organ recipients, allogeneic third party T-cell donors would offer an alternative option. Recent studies showed that during granulocyte colony-stimulating factor (G-CSF) mobilization, the functional activity of antiviral memory T cells is impaired for a long period. This finding suggests that even stem cell donors may not be the best source of T cells. Under these circumstances, partially human leukocyte antigen (HLA)-matched virus-specific CTLs from healthy seropositive individuals may be a promising option. Therefore, frequency assessments of virus-specific memory T cells in HLA-typed healthy donors as well as in HSCT/SOT donors using a high throughput T-cell assay were performed over a period of 4 years at Hannover Medical School. This chapter will address the relevance and potential of a third-party T-cell donor registry and will discuss its clinical implication for adoptive T-cell immunotherapy. PMID:23372567

  2. A Laboratory Test Setup for in Situ Measurements of the Dielectric Properties of Catalyst Powder Samples under Reaction Conditions by Microwave Cavity Perturbation: Set up and Initial Tests

    PubMed Central

    Dietrich, Markus; Rauch, Dieter; Porch, Adrian; Moos, Ralf

    2014-01-01

    The catalytic behavior of zeolite catalysts for the ammonia-based selective catalytic reduction (SCR) of nitrogen oxides (NOX) depends strongly on the type of zeolite material. An essential precondition for SCR is a previous ammonia gas adsorption that occurs on acidic sites of the zeolite. In order to understand and develop SCR active materials, it is crucial to know the amount of sorbed ammonia under reaction conditions. To support classical temperature-programmed desorption (TPD) experiments, a correlation of the dielectric properties with the catalytic properties and the ammonia sorption under reaction conditions appears promising. In this work, a laboratory test setup, which enables direct measurements of the dielectric properties of catalytic powder samples under a defined gas atmosphere and temperature by microwave cavity perturbation, has been developed. Based on previous investigations and computational simulations, a resonator cavity and a heating system were designed, installed and characterized. The resonator cavity is designed to operate in its TM010 mode at 1.2 GHz. The first measurement of the ammonia loading of an H-ZSM-5 zeolite confirmed the operating performance of the test setup at constant temperatures of up to 300 °C. It showed how both real and imaginary parts of the relative complex permittivity are strongly correlated with the mass of stored ammonia. PMID:25211199

  3. Impact of different eddy covariance sensors and set-up on the annual balance of CO2 and fluxes of CH4 and latent heat in the Arctic

    NASA Astrophysics Data System (ADS)

    Goodrich, J. P.; Zona, D.; Gioli, B.; Murphy, P.; Burba, G. G.; Oechel, W. C.

    2015-12-01

    Expanding eddy covariance measurements of CO2 and CH4 fluxes in the Arctic is critical for refining the global C budget. Continuous measurements are particularly challenging because of the remote locations, low power availability, and extreme weather conditions. The necessity for tailoring instrumentation at different sites further complicates the interpretation of results and may add uncertainty to estimates of annual CO2 budgets. We investigated the influence of different sensor combinations on FCO2, latent heat (LE), and FCH4, and assessed the differences in annual FCO2 estimated with different instrumentation at the same sites. Using data from four sites across the North Slope of Alaska, we resolved FCO2 and FCH4 to within 5% using different combinations of open- and closed-path gas analyzers and within 10% using heated and non-heated anemometers. A continuously heated anemometer increased data coverage relative to non-heated anemometers while resulting in comparable annual FCO2, despite over-estimating sensible heat fluxes by 15%. We also implemented an intermittent heating strategy whereby activation only when ice or snow blockage of the transducers was detected. This resulted in comparable data coverage (~ 60%) to the continuously heated anemometer, while avoiding potential over-estimation of sensible heat and gas fluxes. We found good agreement in FCO2 and FCH4 from two closed-path and one open-path gas analyzer, despite the need for large spectral corrections of closed-path fluxes and density and temperature corrections to open-path sensors. However, data coverage was generally greater when using closed-path, especially during cold seasons (36-40% vs 10-14% for the open path), when fluxes from Arctic regions are particularly uncertain and potentially critical to annual C budgets. Measurement of Arctic LE remains a challenge due to strong attenuation along sample tubes, even when heated, that could not be accounted for with spectral corrections.

  4. A comprehensive dose evaluation project concerning animals affected by the Fukushima Daiichi Nuclear Power Plant accident: its set-up and progress.

    PubMed

    Takahashi, Shintaro; Inoue, Kazuya; Suzuki, Masatoshi; Urushihara, Yusuke; Kuwahara, Yoshikazu; Hayashi, Gohei; Shiga, Soichiro; Fukumoto, Motoi; Kino, Yasushi; Sekine, Tsutomu; Abe, Yasuyuki; Fukuda, Tomokazu; Isogai, Emiko; Yamashiro, Hideaki; Fukumoto, Manabu

    2015-12-01

    It is not an exaggeration to say that, without nuclear accidents or the analysis of radiation therapy, there is no way in which we are able to quantify radiation effects on humans. Therefore, the livestock abandoned in the ex-evacuation zone and euthanized due to the Fukushima Daiichi Nuclear Power Plant (FNPP) accident are extremely valuable for analyzing the environmental pollution, its biodistribution, the metabolism of radionuclides, dose evaluation and the influence of internal exposure. We, therefore, sought to establish an archive system and to open it to researchers for increasing our understanding of radiation biology and improving protection against radiation. The sample bank of animals affected by the FNPP accident consists of frozen tissue samples, formalin-fixed paraffin-embedded specimens, dose of radionuclides deposited, etc., with individual sampling data. PMID:26687285

  5. Innovation in Indian Higher Education: Seminar on the Problems Involved in Setting Up New Types of Higher Education Institutions and Programmes in Developing Countries and Regions.

    ERIC Educational Resources Information Center

    Bordia, Anil

    UNESCO has a long record of support for innovative activities in different countries. In India, UNESCO provides assistance for several activities in the field of technical and higher education. This paper describes the effort made in India to render higher education more relevant to the needs of the country and the extent to which the different…

  6. An Optimized Table-Top Small-Angle X-ray Scattering Set-up for the Nanoscale Structural Analysis of Soft Matter

    PubMed Central

    Sibillano, T.; De Caro, L.; Altamura, D.; Siliqi, D.; Ramella, M.; Boccafoschi, F.; Ciasca, G.; Campi, G.; Tirinato, L.; Di Fabrizio, E.; Giannini, C.

    2014-01-01

    The paper shows how a table top superbright microfocus laboratory X-ray source and an innovative restoring-data algorithm, used in combination, allow to analyze the super molecular structure of soft matter by means of Small Angle X-ray Scattering ex-situ experiments. The proposed theoretical approach is aimed to restore diffraction features from SAXS profiles collected from low scattering biomaterials or soft tissues, and therefore to deal with extremely noisy diffraction SAXS profiles/maps. As biological test cases we inspected: i) residues of exosomes' drops from healthy epithelial colon cell line and colorectal cancer cells; ii) collagen/human elastin artificial scaffolds developed for vascular tissue engineering applications; iii) apoferritin protein in solution. Our results show how this combination can provide morphological/structural nanoscale information to characterize new artificial biomaterials and/or to get insight into the transition between healthy and pathological tissues during the progression of a disease, or to morphologically characterize nanoscale proteins, based on SAXS data collected in a room-sized laboratory. PMID:25382272

  7. A comprehensive dose evaluation project concerning animals affected by the Fukushima Daiichi Nuclear Power Plant accident: its set-up and progress.

    PubMed

    Takahashi, Shintaro; Inoue, Kazuya; Suzuki, Masatoshi; Urushihara, Yusuke; Kuwahara, Yoshikazu; Hayashi, Gohei; Shiga, Soichiro; Fukumoto, Motoi; Kino, Yasushi; Sekine, Tsutomu; Abe, Yasuyuki; Fukuda, Tomokazu; Isogai, Emiko; Yamashiro, Hideaki; Fukumoto, Manabu

    2015-12-01

    It is not an exaggeration to say that, without nuclear accidents or the analysis of radiation therapy, there is no way in which we are able to quantify radiation effects on humans. Therefore, the livestock abandoned in the ex-evacuation zone and euthanized due to the Fukushima Daiichi Nuclear Power Plant (FNPP) accident are extremely valuable for analyzing the environmental pollution, its biodistribution, the metabolism of radionuclides, dose evaluation and the influence of internal exposure. We, therefore, sought to establish an archive system and to open it to researchers for increasing our understanding of radiation biology and improving protection against radiation. The sample bank of animals affected by the FNPP accident consists of frozen tissue samples, formalin-fixed paraffin-embedded specimens, dose of radionuclides deposited, etc., with individual sampling data.

  8. Practical aspects involved in the design and set up of a 0.15 T, 6-coil resistive magnet, whole body NMR imaging facility.

    PubMed

    Thomas, S R; Ackerman, J L; Kereiakes, J G

    1984-01-01

    Many technical and logistical questions must be addressed when planning the installation of an NMR imaging system. These considerations become particularly significant when the facility is being established within an existing medical center complex. This paper presents a report on the practical aspects and experience obtained in siting a 6-coil 0.15 T resistive magnet system. The topics discussed include: floor loading; ferromagnetic environment; the effect of iron on the magnet field strength and homogeneity characteristics; shimming procedures; temperature stability requirements; rf shielding; and effects of the magnetic field on common medical instrumentation and magnetic media. It was found that the field shift as a function of the distance of a steel mass from the center of the magnet exhibited an (1/r)5.2 +/- 0.5 to (1/r) 4.2 +/- 0.3 dependence for axial and radial positions respectively which, as expected, is somewhat weaker than the (1/r)6 dependence expected by point dipole approximations. Field distortions caused by the presence of ferromagnetic material in radial positions may be essentially fully compensated with first order transverse shim coils (most conveniently, the x and y imaging gradient coils could be used). Axially distributed material requires, in addition to first order z-gradient correction, higher order axial shim compensation. The temperature stability of the magnet system over the scan period must be better than 0.2 degrees C to insure that temperature-induced field fluctuations are less than the intrinsic static inhomogeneity: and, ideally, below 0.01 degrees C to reduce these fluctuations to less than those caused by power supply instability.

  9. The Setting Up of National, Regional and Sector Targets as a Tool for Reforming the System. Report of the Subgroup A Meeting, 23-24, May, Turin.

    ERIC Educational Resources Information Center

    Loveman, S.

    This paper aims to give partner states of the European Training Foundation material to help them assess the potential value of targets as a tool for reform. It begins with a definition of terms and a brief statement of the potential benefits of target setting. The 10 potential benefits are as follows: provide a focus for planning and action; test…

  10. Exploring Relationships between Setting Up Complex Tasks and Opportunities to Learn in Concluding Whole-Class Discussions in Middle-Grades Mathematics Instruction

    ERIC Educational Resources Information Center

    Jackson, Kara; Garrison, Anne; Wilson, Jonee; Gibbons, Lynsey; Shahan, Emily

    2013-01-01

    This article specifies how the setup, or introduction, of cognitively demanding tasks is a crucial phase of middle-grades mathematics instruction. The authors report on an empirical study of 165 middle-grades mathematics teachers' instruction that focused on how they introduced tasks and the relationship between how they introduced tasks and…

  11. Set-up of a passive Bonner sphere system for neutron spectrometry at mixed fields with predominant photon component based on activation detector.

    PubMed

    Amgarou, K; Lacoste, V; Muller, H; Fernández, F

    2007-01-01

    A passive Bonner sphere system (BSS), based on thermal neutron activation detectors, was developed to perform neutron spectrometry in pulsed and very intense (n-gamma) fields with predominant photon component, as those produced by high energy (>10 MV) medical linear electron accelerators. In this paper, a description of the new system is presented together with an experimental characterisation of a portable Sodium Iodide (NaI) detector and a fixed high-purity Germanium one, both used to measure the induced gamma-activity of the activated materials, respectively, in situ and in the laboratory. The choice of the activated materials is justified according to pre-established practical considerations and physical criteria. The response functions of the entire passive BSS were calculated using the MCNPX code. A preliminary experimental validation with a bare (252)Cf source is given as well.

  12. A survey of current ostrich handling and transport practices in North America with reference to ostrich welfare and transportation guidelines set up in other countries.

    PubMed

    Bejaei, M; Cheng, K M

    2014-02-01

    Appropriate management of an ostrich's exposure to stressors during preslaughter handling and transport practices can improve its well-being and product quality. Because of the lack of information about ostrich farming and transportation in North America and lack of developed Codes of Practice for ratite transport in Canada and the United States, the first objective of our research was to identify current preslaughter handling and transport practices of the ostrich industry in Canada and the United States, and to identify potential welfare issues based on the current practices. The second objective of this research was to review ostrich transport welfare standards and guidelines from Australia, European Union, New Zealand, and South Africa to investigate if those guidelines are applicable to Canadian and American ostrich production systems. Preliminary producer interviews, on-farm visits, and literature review information sources were used to design a producer questionnaire that was used to survey producers by Internet and mail surveying methods to identify existing ostrich transport norms in Canada and the United States. Based on the results of our producer survey and review of the transport standards and guidelines, we conclude that following factors are potential ostrich handling and transport welfare issues in Canada and the United States: lack of scientific information about welfare of ostriches during handling and transport; unfamiliarity of handlers and birds with handling and transport practices; not considering birds' social bounds, sex, behavior, and physical state in mixing them during handling and transport process; lack of an established specific maximum water and feed withdrawal duration for ostrich transport in Canada and the United States; lack of a specific vehicle designed for ratite transportation in Canada and the United States considering different physical body characteristics of ostriches compared with other species; exposure of birds to natural light during transport inside the trailer; overcrowding; and long transportation in Canada and the United States. Results of this research will contribute toward developing Codes of Practice for preslaughter handling, transportation, and slaughter of ostriches in Canada and the United States.

  13. Setting up a CFO Trust Fund: Forging a Bond with Your Director of Finance Will Reap Rewards for Your Institution--And Your Department

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2011-01-01

    While it would be naive to think that every CIO can achieve a rapport with his CFO, understanding the importance of a solid relationship with the head of finance is critical to success, both for the IT department and the institution as a whole. Never has this been truer than in today's bleak economy, as CFOs become increasingly cautious about…

  14. The RAM Studies 1, 2, 3, and 4: A Description of the Thinking, Set-up, and Planning of the Studies. Working Paper.

    ERIC Educational Resources Information Center

    Dollerup, Cay; And Others

    An initial study (Ram 1) in Denmark in 1970 determined whether methods could be developed to assess the effect of textual passages on readers' experiences of a short story. Subjects, 717 Danish secondary students, were given a questionnaire to check on the effect of specific auctorial techniques and to chart readers' attitudes and the way they…

  15. Dosimetry of a set-up for the exposure of newborn mice to 2.45-GHZ WiFi frequencies.

    PubMed

    Pinto, R; Lopresto, V; Galloni, P; Marino, C; Mancini, S; Lodato, R; Pioli, C; Lovisolo, G A

    2010-08-01

    This work describes the dosimetry of a two waveguide cell system designed to expose newborn mice to electromagnetic fields associated with wireless fidelity signals in the frequency band of 2.45 GHz. The dosimetric characterisation of the exposure system was performed both numerically and experimentally. Specific measures were adopted with regard to the increase in both weight and size of the biological target during the exposure period. The specific absorption rate (SAR, W kg(-1)) for 1 W of input power vs. weight curve was assessed. The curve evidenced an SAR pattern varying from <1 W kg(-1) to >6 W kg(-1) during the first 5 weeks of the life of mice, with a peak resonance phenomenon at a weight around 5 g. This curve was used to set the appropriate level of input power during experimental sessions to expose the growing mice to a defined and constant dose.

  16. Setting Up the Next Generation Biofeedback Program for Stress and Anxiety Management for College Students: A Simple and Cost-Effective Approach

    ERIC Educational Resources Information Center

    Ratanasiripong, Paul; Sverduk, Kevin; Hayashino, Diane; Prince, Judy

    2010-01-01

    The increasing prevalence of stress and anxiety on college campuses along with limited resources and budget reductions for many campuses has prompted the need for innovative approaches to help students effectively manage their stress and anxiety. With college students becoming more and more technology-savvy, the authors present an innovative…

  17. How much additional model complexity do the use of catchment hydrological signatures, additional data and expert knowledge warrant?

    NASA Astrophysics Data System (ADS)

    Hrachowitz, M.; Fovet, O.; RUIZ, L.; Gascuel-odoux, C.; Savenije, H.

    2013-12-01

    In the frequent absence of sufficient suitable data to constrain hydrological models, it is not uncommon to represent catchments at a range of scales by lumped model set-ups. Although process heterogeneity can average out on the catchment scale to generate simple catchment integrated responses whose general flow features can frequently be reproduced by lumped models, these models often fail to get details of the flow pattern as well as catchment internal dynamics, such as groundwater level changes, right to a sufficient degree, resulting in considerable predictive uncertainty. Traditionally, models are constrained by only one or two objectives functions, which does not warrant more than a handful of parameters to avoid elevated predictive uncertainty, thereby preventing more complex model set-ups accounting for increased process heterogeneity. In this study it was tested how much additional process heterogeneity is warranted in models when optimizing the model calibration strategy, using additional data and expert knowledge. Long-term timeseries of flow and groundwater levels for small nested experimental catchments in French Brittany with considerable differences in geology, topography and flow regime were used in this study to test which degree of model process heterogeneity is warranted with increased availability of information. In a first step, as a benchmark, the system was treated as one lumped entity and the model was trained based only on its ability to reproduce the hydrograph. Although it was found that the overall modelled flow generally reflects the observed flow response quite well, the internal system dynamics could not be reproduced. In further steps the complexity of this model was gradually increased, first by adding a separate riparian reservoir to the lumped set-up and then by a semi-distributed set-up, allowing for independent, parallel model structures, representing the contrasting nested catchments. Although calibration performance increased

  18. Experimental approaches for gene regulatory network construction: the chick as a model system

    PubMed Central

    Streit, Andrea; Tambalo, Monica; Chen, Jingchen; Grocott, Timothy; Anwar, Maryam; Sosinsky, Alona; Stern, Claudio D.

    2012-01-01

    Setting up the body plan during embryonic development requires the coordinated action of many signals and transcriptional regulators in a precise temporal sequence and spatial pattern. The last decades have seen an explosion of information describing the molecular control of many developmental processes. The next challenge is to integrate this information into logic ‘wiring diagrams’ that visualise gene actions and outputs, have predictive power and point to key control nodes. Here we provide an experimental workflow on how to construct gene regulatory networks using the chick as model system. Keywords: transcription factors, transcriptome analysis, conserved regulatory elements PMID:23174848

  19. Reactive Flow Modeling of Liquid Explosives via ALE3D/Cheetah Simulations

    SciTech Connect

    Kuo, I W; Bastea, S; Fried, L E

    2010-03-10

    We carried out reactive flow simulations of liquid explosives such as nitromethane using the hydrodynamic code ALE3D coupled with equations of state and reaction kinetics modeled by the thermochemical code Cheetah. The simulation set-up was chosen to mimic cylinder experiments. For pure unconfined nitromethane we find that the failure diameter and detonation velocity dependence on charge diameter are in agreement with available experimental results. Such simulations are likely to be useful for determining detonability and failure behavior for a wide range of experimental conditions and explosive compounds.

  20. Charge Transport in Conjugated Materials: From Theoretical Models to Experimental Systems

    NASA Astrophysics Data System (ADS)

    Olivier, Yoann; Muccioli, Luca; Zannoni, Claudio; Cornil, Jérôme

    2008-09-01

    Charge carrier mobility is the key quantity to characterize the charge transport properties in devices. Based on earlier work of Bässler and co-workers, we set up a Monte-Carlo approach that allows us to calculate mobility using transfer rates derived from Marcus theory. The parameters entering into the rate expression are evaluated by means of different quantum-chemical techniques. Our approach is applied here to a model one-dimensional system made of pentacene molecules as well as to real systems such as crystalline structures and columnar liquid crystal phases.